Science.gov

Sample records for additional protocol ratification

  1. Developments in Assisting Countries in Implementing the IAEA Additional Protocol

    SciTech Connect

    Killinger, Mark H.; Hansen, Linda H.; Cain, Ronald A.; Kovacic, Don N.; Apt, Kenneth E.; VanSickle, Matthew

    2010-08-11

    In 2008, the U.S. Department of Energy (DOE) began assisting selected non-nuclear weapon states in planning and preparing for implementation of the International Atomic Energy Agency’s Additional Protocol (AP). Since then, the AP international implementation program has contributed to the substantial progress made by Vietnam, Thailand, Iraq, and Malaysia in preparing for entry-into-force of the AP. An overall engagement plan has been developed with components designed to train government AP implementing agencies, inform policy makers, conduct outreach to industry and universities, make AP reporting software available and useful, and plan a detailed approach for implementing the declaration and complementary access provisions of the AP. DOE recently began collaborating with Indonesia, which has already entered the AP into force, requiring a second method of engagement somewhat different from that taken with countries that have not entered the AP into force. The AP international implementation program, administered by the International Nuclear Safeguards and Engagement Program, is working more closely with DOE’s International Nonproliferation Export Control Program to ensure countries are aware of and prepared to implement the export/import provisions of the AP. As the AP implementation program matures and helps move countries closer to entry-into-force or improved AP implementation, it is identifying characteristics of a country’s “end-state” that indicate that DOE assistance is no longer required. The U.S. AP Implementation Act and Senate Resolution of Ratification require the Administration to report annually to Congress on measures taken to achieve the adoption of the AP in non-nuclear weapon states. DOE’s AP international implementation program is a significant part of these measures. This paper describes recent developments to increase the scope and effectiveness of the program.

  2. CREATION OF THE MODEL ADDITIONAL PROTOCOL

    SciTech Connect

    Houck, F.; Rosenthal, M.; Wulf, N.

    2010-05-25

    In 1991, the international nuclear nonproliferation community was dismayed to discover that the implementation of safeguards by the International Atomic Energy Agency (IAEA) under its NPT INFCIRC/153 safeguards agreement with Iraq had failed to detect Iraq's nuclear weapon program. It was now clear that ensuring that states were fulfilling their obligations under the NPT would require not just detecting diversion but also the ability to detect undeclared materials and activities. To achieve this, the IAEA initiated what would turn out to be a five-year effort to reappraise the NPT safeguards system. The effort engaged the IAEA and its Member States and led to agreement in 1997 on a new safeguards agreement, the Model Protocol Additional to the Agreement(s) between States and the International Atomic Energy Agency for the Application of Safeguards. The Model Protocol makes explicit that one IAEA goal is to provide assurance of the absence of undeclared nuclear material and activities. The Model Protocol requires an expanded declaration that identifies a State's nuclear potential, empowers the IAEA to raise questions about the correctness and completeness of the State's declaration, and, if needed, allows IAEA access to locations. The information required and the locations available for access are much broader than those provided for under INFCIRC/153. The negotiation was completed in quite a short time because it started with a relatively complete draft of an agreement prepared by the IAEA Secretariat. This paper describes how the Model Protocol was constructed and reviews key decisions that were made both during the five-year period and in the actual negotiation.

  3. DOE Preparation for U.S. Implementation of the Additional Protocol

    SciTech Connect

    Killinger, Mark H.; Hendrickson, Paul L.; Curtis, Michael M.; Mcrae, Larry P.; Kovacic, Donald; Wrenn, George E.; Bedke, Michael L.

    2004-07-01

    The United States signed the International Atomic Energy Agency (IAEA) Additional Protocol (AP) to the Safeguards Agreement in 1998. President Bush submitted the AP to the U.S. Senate for advice and consent to ratification, and the Senate gave that consent unanimously in March 2004. The only remaining major step before implementation is for the President to declare entry into force. For several years, the Department of Energy has been planning for the potential ratification of the AP and its implementation in the DOE Complex. Preparations are taking place in four task areas: directives development, computer reporting system, field trials, and information sessions. Directives development consists of revising DOE Order 142.2 and developing a new associated Manual to incorporate AP provisions. The revised Order describes the AP-related responsibilities of relevant DOE offices, and the Manual provides additional detail on those responsibilities. The AP Reporting System will be a tool to receive and manage declarations that DOE makes to the IAEA. The Reporting System will be computer-based and will be used by DOE headquarters staff, field offices, and contractors. Field trials are intended to test existing AP preparations in the DOE Complex and to discover further actions that are necessary for DOE to be fully prepared for actual AP implementation. An initial field trial was held in November 2003. Information sessions are being designed to explain AP provisions and responsibilities to DOE headquarters and field office staff and to DOE contractors. This paper describes the four tasks and their current status.

  4. Feasibility of a simplified fuel additive evaluation protocol

    SciTech Connect

    Lister, S.J.; Hunzinger, R.D.; Taghizadeh, A.

    1998-12-31

    This report describes the work carried out during the four stages of the first phase of a project that involved the determination of the feasibility of replacing the Association of American Railroads Recommended Practice (ARRP) 503 protocol for testing diesel fuel oil additives with a new procedure using the single cylinder research engine SCRE-251 as the laboratory test engine, which tests for both engine performance as well as emissions compliance. The report begins with a review of the literature on fuel additive testing, then reviews the new US Environmental Protection Agency regulations regarding locomotive diesel emissions. This is followed by a review of the ARRP 503 protocol and the proposed new procedure, a comparison of the ARRP 503 test engines and the SCRE-251, and a study of the SCRE-251`s ability to represent a multi-cylinder medium-speed diesel engine. Appendices include fuel additive manufacturers` information sheets.

  5. The role of additional pulses in electropermeabilization protocols.

    PubMed

    Suárez, Cecilia; Soba, Alejandro; Maglietti, Felipe; Olaiz, Nahuel; Marshall, Guillermo

    2014-01-01

    Electropermeabilization (EP) based protocols such as those applied in medicine, food processing or environmental management, are well established and widely used. The applied voltage, as well as tissue electric conductivity, are of utmost importance for assessing final electropermeabilized area and thus EP effectiveness. Experimental results from literature report that, under certain EP protocols, consecutive pulses increase tissue electric conductivity and even the permeabilization amount. Here we introduce a theoretical model that takes into account this effect in the application of an EP-based protocol, and its validation with experimental measurements. The theoretical model describes the electric field distribution by a nonlinear Laplace equation with a variable conductivity coefficient depending on the electric field, the temperature and the quantity of pulses, and the Penne's Bioheat equation for temperature variations. In the experiments, a vegetable tissue model (potato slice) is used for measuring electric currents and tissue electropermeabilized area in different EP protocols. Experimental measurements show that, during sequential pulses and keeping constant the applied voltage, the electric current density and the blackened (electropermeabilized) area increase. This behavior can only be attributed to a rise in the electric conductivity due to a higher number of pulses. Accordingly, we present a theoretical modeling of an EP protocol that predicts correctly the increment in the electric current density observed experimentally during the addition of pulses. The model also demonstrates that the electric current increase is due to a rise in the electric conductivity, in turn induced by temperature and pulse number, with no significant changes in the electric field distribution. The EP model introduced, based on a novel formulation of the electric conductivity, leads to a more realistic description of the EP phenomenon, hopefully providing more accurate

  6. The Role of Additional Pulses in Electropermeabilization Protocols

    PubMed Central

    Suárez, Cecilia; Soba, Alejandro; Maglietti, Felipe; Olaiz, Nahuel; Marshall, Guillermo

    2014-01-01

    Electropermeabilization (EP) based protocols such as those applied in medicine, food processing or environmental management, are well established and widely used. The applied voltage, as well as tissue electric conductivity, are of utmost importance for assessing final electropermeabilized area and thus EP effectiveness. Experimental results from literature report that, under certain EP protocols, consecutive pulses increase tissue electric conductivity and even the permeabilization amount. Here we introduce a theoretical model that takes into account this effect in the application of an EP-based protocol, and its validation with experimental measurements. The theoretical model describes the electric field distribution by a nonlinear Laplace equation with a variable conductivity coefficient depending on the electric field, the temperature and the quantity of pulses, and the Penne's Bioheat equation for temperature variations. In the experiments, a vegetable tissue model (potato slice) is used for measuring electric currents and tissue electropermeabilized area in different EP protocols. Experimental measurements show that, during sequential pulses and keeping constant the applied voltage, the electric current density and the blackened (electropermeabilized) area increase. This behavior can only be attributed to a rise in the electric conductivity due to a higher number of pulses. Accordingly, we present a theoretical modeling of an EP protocol that predicts correctly the increment in the electric current density observed experimentally during the addition of pulses. The model also demonstrates that the electric current increase is due to a rise in the electric conductivity, in turn induced by temperature and pulse number, with no significant changes in the electric field distribution. The EP model introduced, based on a novel formulation of the electric conductivity, leads to a more realistic description of the EP phenomenon, hopefully providing more accurate

  7. The role of additional pulses in electropermeabilization protocols.

    PubMed

    Suárez, Cecilia; Soba, Alejandro; Maglietti, Felipe; Olaiz, Nahuel; Marshall, Guillermo

    2014-01-01

    Electropermeabilization (EP) based protocols such as those applied in medicine, food processing or environmental management, are well established and widely used. The applied voltage, as well as tissue electric conductivity, are of utmost importance for assessing final electropermeabilized area and thus EP effectiveness. Experimental results from literature report that, under certain EP protocols, consecutive pulses increase tissue electric conductivity and even the permeabilization amount. Here we introduce a theoretical model that takes into account this effect in the application of an EP-based protocol, and its validation with experimental measurements. The theoretical model describes the electric field distribution by a nonlinear Laplace equation with a variable conductivity coefficient depending on the electric field, the temperature and the quantity of pulses, and the Penne's Bioheat equation for temperature variations. In the experiments, a vegetable tissue model (potato slice) is used for measuring electric currents and tissue electropermeabilized area in different EP protocols. Experimental measurements show that, during sequential pulses and keeping constant the applied voltage, the electric current density and the blackened (electropermeabilized) area increase. This behavior can only be attributed to a rise in the electric conductivity due to a higher number of pulses. Accordingly, we present a theoretical modeling of an EP protocol that predicts correctly the increment in the electric current density observed experimentally during the addition of pulses. The model also demonstrates that the electric current increase is due to a rise in the electric conductivity, in turn induced by temperature and pulse number, with no significant changes in the electric field distribution. The EP model introduced, based on a novel formulation of the electric conductivity, leads to a more realistic description of the EP phenomenon, hopefully providing more accurate

  8. Department of Energy Efforts to Promote Universal Adherence to the IAEA Additional Protocol

    SciTech Connect

    Killinger, Mark H.; Hansen, Linda H.; Kovacic, Don N.; VanSickle, Matthew; Apt, Kenneth E.

    2009-10-06

    Entry-into-force of the U.S. Additional Protocol (AP) in January 2009 continues to demonstrate the ongoing commitment by the United States to promote universal adherence to the AP. The AP is a critical tool for improving the International Atomic Energy Agency’s (IAEA) capabilities to detect undeclared activities that indicate a clandestine nuclear weapons program. This is because States Parties are required to provide information about, and access to, nuclear fuel cycle activities beyond their traditional safeguards reporting requirements. As part of the U.S. AP Implementation Act and Senate Resolution of Ratification, the Administration is required to report annually to Congress on measures taken to achieve the adoption of the AP in non-nuclear weapon states, as well as assistance to the IAEA to promote the effective implementation of APs in those states. A key U.S. effort in this area is being managed by the International Nuclear Safeguards and Engagement Program (INSEP) of the U.S. Department of Energy (DOE). Through new and existing bilateral cooperation agreements, INSEP has initiated technical assistance projects for AP implementation with selected non-weapon states. States with which INSEP is currently cooperating include Vietnam and Thailand, with Indonesia, Algeria, Morocco, and other countries as possible future collaborators in the area of AP implementation. The INSEP collaborative model begins with a joint assessment with our partners to identify specific needs they may have regarding entering the AP into force and any impediments to successful implementation. An action plan is then developed detailing and prioritizing the necessary joint activities. Such assistance may include: advice on developing legal frameworks and regulatory documents; workshops to promote understanding of AP requirements; training to determine possible declarable activities; assistance in developing a system to collect and submit declarations; performing industry outreach to

  9. International Workshops to Foster Implementation of the IAEA Additional Protocol

    SciTech Connect

    Killinger, Mark H.; Coates, Cameron W.; Bedke, Michael L.

    2003-07-14

    A country’s adherence to the International Atomic Energy Agency’s (IAEA) Additional Protocol is an important statement to the world of that country’s commitment to nuclear nonproliferation. Without the Additional Protocol (AP) it is possible, as demonstrated in Iraq, for a country party to the Non-Proliferation Treaty (NPT) to clandestinely work toward nuclear weapons and be undetected by the IAEA. This is because classical safeguards under the NPT are directed at diversion of nuclear material from declared activities. But a country may instead build undeclared activities to produce weapons-grade nuclear material. The AP is directed at detecting those undeclared activities. As of May 2003, 73 countries had signed the AP, but only 35 have entered into force. To further adherence to the AP, the IAEA has held regional, high-level seminars in Japan, South Africa, Kazakhstan, Peru, Romania, and Malaysia to explain AP provisions. To supplement these policy-level seminars, the U.S. Department of Energy (DOE) has undertaken to develop a set of modules of technical competencies required to implement the AP. The intent is to work closely with the IAEA by providing these technical competencies to countries as well as to complement the IAEA’s regional seminars and other outreach efforts. This paper briefly describes the technical competency modules.

  10. Recommended Protocol for Round Robin Studies in Additive Manufacturing

    PubMed Central

    Moylan, Shawn; Brown, Christopher U.; Slotwinski, John

    2016-01-01

    One way to improve confidence and encourage proliferation of additive manufacturing (AM) technologies and parts is by generating more high quality data describing the performance of AM processes and parts. Many in the AM community see round robin studies as a way to generate large data sets while distributing the cost among the participants, thereby reducing the cost to individual users. The National Institute of Standards and Technology (NIST) has conducted and participated in several of these AM round robin studies. While the results of these studies are interesting and informative, many of the lessons learned in conducting these studies concern the logistics and methods of the study and unique issues presented by AM. Existing standards for conducting interlaboratory studies of measurement methods, along with NIST’s experience, form the basis for recommended protocols for conducting AM round robin studies. The role of round robin studies in AM qualification, some of the limitations of round robin studies, and the potential benefit of less formal collaborative experiments where multiple factors, AM machine being only one, are varied simultaneously are also discussed. PMID:27274602

  11. 48 CFR 2801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Authority, and Responsibilities 2801.602-3 Ratification of unauthorized commitments. The HCA may delegate... will be determined by the HCA. Copies of all ratifications are to be provided to the PE....

  12. 48 CFR 301.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... that clearly states that ratification of a previously unauthorized act is intended. (2) The HCA is the... HCA may redelegate ratification authority for actions up to $100,000 to the Chief of the Contracting... legal review is necessary, the HCA or CCO shall coordinate the request for ratification with the...

  13. Explaining patterns in the ratification of global environmental treaties

    NASA Technical Reports Server (NTRS)

    Cook, David W.

    1991-01-01

    A study was made of the ratification behavior of 160 countries with respect to 38 global environmental treaties. The study identifies and explains patterns in the ratification of treaties, providing two means of assessing the likelihood that any given country will support global environmental treaties. National ratification totals reveal a pattern of high ratification by countries in Western Europe, North America, Japan, Australia, and New Zealand. A country's standing within the range of high to low ratification rates can be explained by the statistical model developed in the study. This research allows one to identify countries likely to support global environmental treaties.

  14. 48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol....

  15. 48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol....

  16. 48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol....

  17. 48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol....

  18. 48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol....

  19. 48 CFR 1352.201-71 - Ratification release.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Ratification release. As prescribed in 48 CFR 1301.602-3, insert the following clause: Ratification Release (APR 2010) (a) The Government agrees to pay the contractor $____ for the following items/services: (b... out of the performance of this contract, which are not known to the Contractor on the date of...

  20. 12 CFR 1278.6 - Ratification by Bank members.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Ratification by Bank members. 1278.6 Section 1278.6 Banks and Banking FEDERAL HOUSING FINANCE AGENCY FEDERAL HOME LOAN BANKS VOLUNTARY MERGERS OF FEDERAL HOME LOAN BANKS § 1278.6 Ratification by Bank members. (a) Requirements for member vote. No...

  1. 12 CFR 1278.6 - Ratification by Bank Members.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Ratification by Bank Members. 1278.6 Section 1278.6 Banks and Banking FEDERAL HOUSING FINANCE AGENCY FEDERAL HOME LOAN BANKS VOLUNTARY MERGERS OF FEDERAL HOME LOAN BANKS § 1278.6 Ratification by Bank Members. (a) Requirements for member vote. No...

  2. 12 CFR 1278.6 - Ratification by Bank Members.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Ratification by Bank Members. 1278.6 Section 1278.6 Banks and Banking FEDERAL HOUSING FINANCE AGENCY FEDERAL HOME LOAN BANKS VOLUNTARY MERGERS OF FEDERAL HOME LOAN BANKS § 1278.6 Ratification by Bank Members. (a) Requirements for member vote. No...

  3. 48 CFR 901.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... paragraph (b)(2) of this section is delegated to the Head of the Contracting Activity (HCA) for individual unauthorized commitments of $25,000 or under. The ratification authority of the HCA is nondelegable....

  4. Diffusion of Innovations Theory Applied to Global Tobacco Control Treaty Ratification

    PubMed Central

    Valente, Thomas W.; Dyal, Stephanie R.; Chu, Kar-Hai; Wipfli, Heather; Fujimoto, Kayo

    2015-01-01

    This study applies diffusion of innovations theory to understand network influences on country ratification of an international health treaty, the Framework Convention for Tobacco Control (FCTC). From 2003 to 2014 approximately 90% of United Nations member countries ratified the FCTC. We hypothesized that communication between tobacco control advocates on GLOBALink, a 7,000-member online communication forum in existence from 1992 to 2012, would be associated with the timing of treaty ratification. We further hypothesized dynamic network influences such that external influence decreased over time, internal influence increased over time, and the role of opinion leader countries varied over time. In addition we develop two concepts: Susceptibility and influence that uncover the micro-level dynamics of network influence. Statistical analyses lend support to the influence of co-subscriptions on GLOBALink providing a conduit for inter-country influences on treaty ratification and some support for the dynamic hypotheses. Analyses of susceptibility and infection indicated particularly influential countries. These results have implications for the study of policy diffusion as well as dynamic models of behavior change. PMID:26460508

  5. 25 CFR 81.7 - Adoption, ratification, or revocation by majority vote.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Adoption, ratification, or revocation by majority vote... TRIBAL REORGANIZATION UNDER A FEDERAL STATUTE § 81.7 Adoption, ratification, or revocation by majority... those actually voting are in favor of adoption, ratification, or revocation. The total vote...

  6. 25 CFR 81.7 - Adoption, ratification, or revocation by majority vote.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Adoption, ratification, or revocation by majority vote... TRIBAL REORGANIZATION UNDER A FEDERAL STATUTE § 81.7 Adoption, ratification, or revocation by majority... those actually voting are in favor of adoption, ratification, or revocation. The total vote...

  7. 25 CFR 81.7 - Adoption, ratification, or revocation by majority vote.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Adoption, ratification, or revocation by majority vote... TRIBAL REORGANIZATION UNDER A FEDERAL STATUTE § 81.7 Adoption, ratification, or revocation by majority... those actually voting are in favor of adoption, ratification, or revocation. The total vote...

  8. 25 CFR 81.7 - Adoption, ratification, or revocation by majority vote.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Adoption, ratification, or revocation by majority vote. 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.7 Adoption, ratification, or revocation by majority vote. Except as... voting are in favor of adoption, ratification, or revocation. The total vote cast, however, must be...

  9. 25 CFR 81.7 - Adoption, ratification, or revocation by majority vote.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Adoption, ratification, or revocation by majority vote... TRIBAL REORGANIZATION UNDER A FEDERAL STATUTE § 81.7 Adoption, ratification, or revocation by majority... those actually voting are in favor of adoption, ratification, or revocation. The total vote...

  10. 48 CFR 701.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 701.602-3 Section 701.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career Development,...

  11. 48 CFR 1201.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 1201.602-3 Section 1201.602-3 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority...

  12. 48 CFR 3401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 3401.602-3 Section 3401.602-3 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Career Development,...

  13. 48 CFR 2901.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Ratification of unauthorized commitments. 2901.602-3 Section 2901.602-3 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL DEPARTMENT OF LABOR ACQUISITION REGULATION SYSTEM Career Development,...

  14. 48 CFR 1.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Ratification of unauthorized commitments. 1.602-3 Section 1.602-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority,...

  15. 48 CFR 701.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Ratification of unauthorized commitments. 701.602-3 Section 701.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career Development,...

  16. 48 CFR 901.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 901.602-3 Section 901.602-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority,...

  17. 48 CFR 801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 801.602-3 Section 801.602-3 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career...

  18. 48 CFR 301.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Ratification of unauthorized commitments. 301.602-3 Section 301.602-3 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority,...

  19. 48 CFR 1401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Ratification of unauthorized commitments. 1401.602-3 Section 1401.602-3 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Career...

  20. 48 CFR 2401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Ratification of unauthorized commitments. 2401.602-3 Section 2401.602-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career...

  1. 48 CFR 701.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Ratification of unauthorized commitments. 701.602-3 Section 701.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career Development,...

  2. 48 CFR 2401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Ratification of unauthorized commitments. 2401.602-3 Section 2401.602-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career...

  3. 48 CFR 1.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Ratification of unauthorized commitments. 1.602-3 Section 1.602-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority,...

  4. 48 CFR 701.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Ratification of unauthorized commitments. 701.602-3 Section 701.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career Development,...

  5. 48 CFR 801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Ratification of unauthorized commitments. 801.602-3 Section 801.602-3 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career...

  6. 48 CFR 2801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Ratification of unauthorized commitments. 2801.602-3 Section 2801.602-3 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE GENERAL DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Career Development,...

  7. 48 CFR 2801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Ratification of unauthorized commitments. 2801.602-3 Section 2801.602-3 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE GENERAL DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Career Development,...

  8. 48 CFR 801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... who lack contracting authority. (b) A contracting officer must not ratify unauthorized commitments... unauthorized commitments. 801.602-3 Section 801.602-3 Federal Acquisition Regulations System DEPARTMENT OF..., Contracting Authority, and Responsibilities 801.602-3 Ratification of unauthorized commitments. (a)...

  9. Effect of Tax Ratification Elections on Student Achievement

    ERIC Educational Resources Information Center

    Groppel, Lance

    2013-01-01

    This dissertation examines the impact a Tax Ratification Election has on student achievement in Texas. Texas schools continue to struggle with shrinking budgets and increasing standards of student achievement (Equity Center, 2011). This study will provide greater insight into whether school districts that have completed a TRE have created a…

  10. 48 CFR 2401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 2401.602-3 Section 2401.602-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career...

  11. 48 CFR 2801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 2801.602-3 Section 2801.602-3 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE GENERAL DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Career Development,...

  12. 48 CFR 2901.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Ratification of unauthorized commitments. 2901.602-3 Section 2901.602-3 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL DEPARTMENT OF LABOR ACQUISITION REGULATION SYSTEM Career Development,...

  13. 48 CFR 2401.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Ratification of unauthorized commitments. 2401.602-3 Section 2401.602-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Career...

  14. 48 CFR 2801.602-3 - Ratification of unauthorized commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Ratification of unauthorized commitments. 2801.602-3 Section 2801.602-3 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Career Development,...

  15. Implementation of the IAEA Additional Protocol in the Philippines: USDOE/PNRI Cooperation

    SciTech Connect

    Sequis, Julietta E.; Cain, Ronald A.; Burbank, Roberta L.; Hansen, Linda H.; VanSickle, Matthew; Killinger, Mark H.; Elkhamri, Oksana O.

    2011-07-19

    The Philippines entered into force the International Atomic Energy Agency (IAEA) Additional Protocol (AP) in February 2010. The Philippine Nuclear Research Institute (PNRI) is the government agency responsible for implementing the AP. In June 2010 the IAEA invited the U.S. Department of Energy (DOE) to help conduct a joint national training seminar on the AP. DOE presented to PNRI its AP international technical assistance program, administered by the International Nuclear Safeguards and Engagement Program (INSEP), which helps partner countries implement the AP. In coordination with the IAEA, DOE established this program in 2008 to complement IAEA AP seminars with long-term country-specific cooperation from the perspective of a Member State. The US version of the AP is the same version as that of non-nuclear weapon states except for the addition of a national security exclusion. Due to this, DOE cooperation with other countries enables the sharing of valuable lessons learned in implementing the AP. DOE/INSEP described to PNRI the various areas of cooperation it offers to interested countries, whether they are preparing for entry into force or already implementing the AP. Even countries that have entered the AP into force are sometimes not fully prepared to implement it well, and welcome cooperation to improve their implementation process. PNRI and DOE/INSEP subsequently agreed to cooperate in several areas to enhance the efficiency and effectiveness of the Philippines AP implementation. These areas include providing working-level training to PNRI staff and preparing an information document that details that training for future reference, assisting with the development of an outreach program and procedures for AP reporting and complementary access, and identifying Annex II equipment and non-nuclear materials whose export must be reported under the AP. DOE laboratory representatives, funded by INSEP, met again with PNRI in February 2011 to provide training for PNRI AP

  16. 48 CFR 49.108-4 - Authorization for subcontract settlements without approval or ratification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.108-4 Authorization for subcontract settlements without approval or ratification. (a)(1)...

  17. 75 FR 4323 - Additional Quantitative Fit-testing Protocols for the Respiratory Protection Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... performed particle counts on samples collected during the Study. Table 1 provides the exercise and sampling... revised PortaCount quantitative fit-testing protocols are not sufficiently accurate or reliable to include...) to Appendix A of ] its Respiratory Protection Standard (see 69 FR 46986). OSHA also published...

  18. 10 CFR 205.14 - Ratification of prior directives, orders, and actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Ratification of prior directives, orders, and actions. 205.14 Section 205.14 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS General Provisions § 205.14 Ratification of prior directives, orders, and actions. All interpretations,...

  19. The Ratification of Spain of the European Charter for Regional or Minority Languages. Mercator Working Papers.

    ERIC Educational Resources Information Center

    Surribas, Santiago Castella

    This report describes the development and approval of the European Charter for Regional or Minority Languages. After discussing the expression of consent to the European Charter, the report focuses on the ratification process of and obligations assumed by Spain. Although Spain was one of the first signatories in 1992, the ratification was not…

  20. 48 CFR 49.108-4 - Authorization for subcontract settlements without approval or ratification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... subparagraph (4) below, the TCO shall accept, as part of the prime contractor's settlement proposal... subcontract settlements without approval or ratification. 49.108-4 Section 49.108-4 Federal Acquisition... Principles 49.108-4 Authorization for subcontract settlements without approval or ratification. (a)(1)...

  1. Does ratification of human-rights treaties have effects on population health?

    PubMed

    Palmer, Alexis; Tomkinson, Jocelyn; Phung, Charlene; Ford, Nathan; Joffres, Michel; Fernandes, Kimberly A; Zeng, Leilei; Lima, Viviane; Montaner, Julio S G; Guyatt, Gordon H; Mills, Edward J

    2009-06-01

    Human-rights treaties indicate a country's commitment to human rights. Here, we assess whether ratification of human-rights treaties is associated with improved health and social indicators. Data for health (including HIV prevalence, and maternal, infant, and child [<5 years] mortalities) and social indicators (child labour, human development index, sex gap, and corruption index), gathered from 170 countries, showed no consistent associations between ratification of human-rights treaties and health or social outcomes. Established market economy states had consistently improved health compared with less wealthy settings, but this was not associated with treaty ratification. The status of treaty ratification alone is not a good indicator of the realisation of the right to health. We suggest the need for stringent requirements for ratification of treaties, improved accountability mechanisms to monitor compliance of states with treaty obligations, and financial assistance to support the realisation of the right to health.

  2. A comparison of the additional protocols of the five nuclear weapon states and the ensuing safeguards benefits to international nonproliferation efforts

    SciTech Connect

    Uribe, Eva C; Sandoval, M Analisa; Sandoval, Marisa N; Boyer, Brian D; Leitch, Rosalyn M

    2009-01-01

    With the 6 January 2009 entry into force of the Additional Protocol by the United States of America, all five declared Nuclear Weapon States that are part of the Nonproliferation Treaty have signed, ratified, and put into force the Additional Protocol. This paper makes a comparison of the strengths and weaknesses of the five Additional Protocols in force by the five Nuclear Weapon States with respect to the benefits to international nonproliferation aims. This paper also documents the added safeguards burden to the five declared Nuclear Weapon States that these Additional Protocols put on the states with respect to access to their civilian nuclear programs and the hosting of complementary access activities as part of the Additional Protocol.

  3. 76 FR 24854 - Proposed Information Collection; Comment Request; Additional Protocol Report Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... International Atomic Energy Agency (IAEA) on a number of commercial nuclear and nuclear-related items, materials... for a nuclear weapons program. These forms provides the IAEA with information about additional aspects...; buildings on sites of facilities selected by the IAEA from the U.S. Eligible Facilities List;...

  4. Additives

    NASA Technical Reports Server (NTRS)

    Smalheer, C. V.

    1973-01-01

    The chemistry of lubricant additives is discussed to show what the additives are chemically and what functions they perform in the lubrication of various kinds of equipment. Current theories regarding the mode of action of lubricant additives are presented. The additive groups discussed include the following: (1) detergents and dispersants, (2) corrosion inhibitors, (3) antioxidants, (4) viscosity index improvers, (5) pour point depressants, and (6) antifouling agents.

  5. [ILO conventions on occupational safety and health with reference to ratification status of Japan].

    PubMed

    Takahashi, K; Okubo, T

    1995-07-01

    This paper grouped together recent ILO conventions relevant to occupational safety and health (OSH) in order to clarify their characteristics and form an overview. There are 13 such conventions adopted by ILO during the period 1960-1993. Each of these conventions have distinct goals to cover respective areas of OSH, which was contrasted with each other. Conventions are subject to ratification, thus the ratification status of Japan was statistically compared to that of ILO and OECD member states. As at June 1993, Japan ratified three of such conventions, which was slightly higher than the average number ratified by all ILO member states and ranked 11th among 24 OECD member states. The relative ratification status of Japan on ILO Conventions fared better with those relevant to OSH than others. ILO Conventions are inter-related by reference and note, thus ratification of basic conventions such as C. 155 (Occupational Safety and Health Convention) and C. 148 (Working Environment Convention), neither of which is ratified by Japan, should be prioritized to further promote ratification status in the OSH area.

  6. Lessons Learned at the Idaho National Laboratory for the Entry into Force of the U.S. Additional Protocol

    SciTech Connect

    Jeffrey C. Joe; Shauna A. Hoiland

    2009-07-01

    For a number of years, the Idaho National Laboratory (INL) has been preparing for the entry into force of the U.S. Additional Protocol (AP). These preparations included attending training, participating in tabletop exercises, preparing draft declarations, developing INL-specific guidance documents, preparing for and hosting a mock complementary access visit, and preparing declarations for official submittal. All of these activities, the training materials, and software developed by other U.S. DOE national laboratories (PNNL, ORNL, LANL, and BNL) were very helpful in preparing for the entry into force of the AP. As with any endeavor of this size and complexity, however, there are always instances where even the best preparations and advanced planning do not anticipate every challenge. As the DOE's lead nuclear energy research and development facility, the INL faced many unique challenges. The majority of research conducted at the INL is nuclear fuel cycle related, most of which is not protected by the National Security Exclusion. This paper describes the lessons learned from the INL’s experience of preparing for the entry into force of the AP, specifically how translating and implementing general principles into actual activities proved to be one of many challenges, and provides general suggestions on how to respond effectively and efficiently to routine annual data calls and other AP requests.

  7. 77 FR 15231 - Delegation of Responsibility Under the Senate Resolution of Advice and Consent to Ratification of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ..., Washington, March 6, 2012 [FR Doc. 2012-6449 Filed 3-14-12; 8:45 am] Billing code 4710-10-P ... Under the Senate Resolution of Advice and Consent to Ratification of the Treaty Between the Government..., consistent with section 2 of the Senate Resolution of Advice and Consent to Ratification of the Treaty,...

  8. Challenges of the Harmonization and Ratification of Convention on the Rights of Persons with Disabilities by Japan

    ERIC Educational Resources Information Center

    Osamu, Nagase

    2013-01-01

    There are 130 ratifications by national governments around the world of the Convention on the Rights of Persons with Disabilities (CRPD), adopted by the United Nations in December 2006. However, Japan has yet to ratify the CRPD. The author examined the social, political, and legal context in Japan, affecting the ratification of the CRPD and…

  9. Lessons learned during the training exercise for the entry into force of the U.S. additional protocol in the DOE complex

    SciTech Connect

    Boyer, Brian D

    2009-01-01

    In 2008 in anticipation of the United States bringing into force the Additional Protocol in early 2009 DOE/NNSA planned and executed training exercises in the conduct of Additional Protocol complementary access activities. Brookhaven National Laboratory and Los Alamos National Laboratory together produced the exercises designed to prepare the following types of DOE laboratories for complementary access - weapons laboratories, nuclear engineering laboratories, and science laboratories. This panel provides a forum to discuss and summarize the results and lessons learned from the 2008 exercise.

  10. The Writing and Ratification of the U.S. Constitution: A Bibliography. Education and Training Series.

    ERIC Educational Resources Information Center

    Wheeler, Russell R.

    This bibliography focuses on the origins and development of the United States Constitution. This single bibliography is organized into two versions: (1) The Abbreviated Bibliography provides a long catalog of some major sources for a basic understanding of the events and ideas of the writing and ratification of the Constitution; and (2) the…

  11. The Ratification of the Constitution. The U.S. Army Bicentennial Series, No. 26.

    ERIC Educational Resources Information Center

    Army Center of Military History, Washington, DC.

    After 38 of the 41 delegates signed it on September 17, 1787, the U.S. Constitution was sent to the Continental Congress in New York where a vote was taken to pass the document to the 13 states for ratification. The process began with a struggle in Congress between those who favored the document, or the Federalists, and those who opposed it, or…

  12. Remote Sensing and the Kyoto Protocol: A Workshop Summary

    NASA Technical Reports Server (NTRS)

    Rosenqvist, Ake; Imhoff, Marc; Milne, Anthony; Dobson, Craig

    2000-01-01

    The Kyoto Protocol to the United Nations Framework Convention on Climate Change contains quantified, legally binding commitments to limit or reduce greenhouse gas emissions to 1990 levels and allows carbon emissions to be balanced by carbon sinks represented by vegetation. The issue of using vegetation cover as an emission offset raises a debate about the adequacy of current remote sensing systems and data archives to both assess carbon stocks/sinks at 1990 levels, and monitor the current and future global status of those stocks. These concerns and the potential ratification of the Protocol among participating countries is stimulating policy debates and underscoring a need for the exchange of information between the international legal community and the remote sensing community. On October 20-22 1999, two working groups of the International Society for Photogrammetry and Remote Sensing (ISPRS) joined with the University of Michigan (Michigan, USA) to convene discussions on how remote sensing technology could contribute to the information requirements raised by implementation of, and compliance with, the Kyoto Protocol. The meeting originated as a joint effort between the Global Monitoring Working Group and the Radar Applications Working Group in Commission VII of the ISPRS, co-sponsored by the University of Michigan. Tile meeting was attended by representatives from national government agencies and international organizations and academic institutions. Some of the key themes addressed were: (1) legal aspects of transnational remote sensing in the context of the Kyoto Protocol; (2) a review of the current and future and remote sensing technologies that could be applied to the Kyoto Protocol; (3) identification of areas where additional research is needed in order to advance and align remote sensing technology with the requirements and expectations of the Protocol; and 94) the bureaucratic and research management approaches needed to align the remote sensing

  13. In Brief: Kyoto Protocol moves forward

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2004-10-01

    The Russian cabinet's 30 September endorsement of the Kyoto Protocol to the United Nations Framework Convention on Climate Change (UNFCCC) likely clears the way for the treaty's ratification by that country's parliament and for its entry into force. The protocol enters into force when not less than 55 Parties to the Convention, including industrialized countries (so called ``Annex I Parties'') which accounted in total for at least 55 % of the total carbon dioxide emissions for 1990 from that group, officially have agreed to the treaty.

  14. The Kyoto Protocol: A business perspective

    SciTech Connect

    Malin, C.B.

    1998-01-19

    Governments have made a tentative start in responding to climate change. In marathon negotiating sessions that extended into an extra day Dec. 1--11 in Kyoto, Japan, representatives from more than 160 governments hammered out the Kyoto Protocol to the United Nations Framework Convention on Climate Change (FCCC). The protocol calls for developed countries to reduce emissions of greenhouse gases (GHGs) on averaged by 5.2% below 1990 levels by the years 2008--2012. Developing countries have no new obligations. The paper discusses the agreement, ratification, future questions, business role, and the challenge.

  15. Global warming and environmental production efficiency ranking of the Kyoto Protocol nations.

    PubMed

    Feroz, Ehsan H; Raab, Raymond L; Ulleberg, Gerald T; Alsharif, Kamal

    2009-02-01

    This paper analyzes the United Nations Organization's Kyoto Protocol nations to address two questions. First, what are the environmental production efficiency rankings of these nations? Second, is there a relationship between a nation's ratification status and its environmental production efficiency ranking? Our findings suggest that the nations that have ratified the Kyoto Protocol are more likely to be environmentally production efficient as compared to the nations that have not ratified the Protocol.

  16. Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2008).

    PubMed

    Carstens, E B; Ball, L A

    2009-01-01

    In accordance with the Statutes of the International Committee of Taxonomy of Viruses (ICTV), the final stage in the process of making changes to the Universal Scheme of Virus Classification is the ratification of taxonomic proposals by ICTV Members. This can occur either at a Plenary meeting of ICTV, held during an International Congress of Virology meeting, or by circulation of proposals by mail followed by a ballot. Therefore, a list of proposals that had been subjected to the full, multi-stage review process was prepared and presented on the ICTVonline web pages in March 2008. This review process involved input from the ICTV Study Groups and Subcommittees, other interested virologists, and the ICTV Executive Committee. For the first time, the ratification process was performed entirely by email. The proposals were sent electronically via email on 18 March 2008 to ICTV Life Members (11), ICTV Subcommittee Members (74), and ICTV National Representatives (53).

  17. Removing the deadline for the ratification of the equal rights amendment.

    THOMAS, 113th Congress

    Rep. Andrews, Robert E. [D-NJ-1

    2013-05-09

    03/12/2014 Ms. Speier asked unanimous consent that she be considered the first sponsor of H.J. Res. 43, removing the deadline for the ratification of the equal rights amendment, a bill originally introduced by Representative Robert Andrews of New Jersey, for the purposes of adding... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  18. REVIEW OF THE NEGOTIATION OF THE MODEL PROTOCOL ADDITIONAL TO THE AGREEMENT(S) BETWEEN STATE(S) AND THE INTERNATIONAL ATOMIC ENERGY AGENCY FOR THE APPLICATION OF SAFEGUARDS, INFCIRC/540 (Corrected) VOLUME II/III IAEA COMMITTEE 24, Major Issues Underlying the Model Additional Protocol (1996-1997).

    SciTech Connect

    Rosenthal, M.D.; Saum-Manning, L.; Houck, F.

    2010-01-01

    Volume I of this Review traces the origins of the Model Additional Protocol. It covers the period from 1991, when events in Iraq triggered an intensive review of the safeguards system, until 1996, when the IAEA Board of Governors established Committee 24 to negotiate a new protocol to safeguards agreement. The period from 1991-1996 set the stage for this negotiation and shaped its outcome in important ways. During this 5-year period, many proposals for strengthening safeguards were suggested and reviewed. Some proposals were dropped, for example, the suggestion by the IAEA Secretariat to verify certain imports, and others were refined. A rough consensus was established about the directions in which the international community wanted to go, and this was reflected in the draft of an additional protocol that was submitted to the IAEA Board of Governors on May 6, 1996 in document GOV/2863, Strengthening the Effectiveness and Improving the Efficiency of the Safeguards System - Proposals For Implementation Under Complementary Legal Authority, A Report by the Director General. This document ended with a recommendation that, 'the Board, through an appropriate mechanism, finalize the required legal instrument taking as a basis the draft protocol proposed by the Secretariat and the explanation of the measures contained in this document.'

  19. The ratification status of ILO conventions related to occupational safety and health and its relationship with reported occupational fatality rates.

    PubMed

    Wilson, Donald J; Takahashi, Ken; Sakuragi, Sonoko; Yoshino, Masako; Hoshuyama, Tsutomu; Imai, Teppei; Takala, Jukka

    2007-01-01

    The aim of this study was to assess the relationship between the ratification status of occupational safety and health (OSH)-related ILO conventions and reported occupational fatality rates of ILO member countries, while controlling for possible confounding factors. ILO member states were divided into 4 levels of income status, based on the gross national income per capita. Seventeen conventions designated as OSH-related were examined. Reported country occupational fatality rates were compared according to the ratification status of these 17 conventions and multiple regression analyses were conducted to assess the relationship between the fatality rates, ratification status, income level and length of ILO membership. Fatality rates were inversely and significantly related to income levels. In general, non-ratifying countries had higher work-related fatality rates than ratifying countries. A statistical model for identifying predictors of fatal injury rates showed that a larger number of conventions ratified was significantly associated with lower fatality rates. The fact that non-ratifying countries generally have higher fatality rates than ratifying ones supports the notion that all countries should promote ratification of ILO conventions aimed at improving OSH conditions.

  20. Patient rights in EU Member States after the ratification of the Convention on Human Rights and Biomedicine.

    PubMed

    Nys, Herman; Stultiëns, Loes; Borry, Pascal; Goffin, Tom; Dierickx, Kris

    2007-10-01

    The European Convention on Human Rights and Biomedicine was adopted by the Committee of Ministers of the Council of Europe on 19 November 1996 and opened for signature in Oviedo, Spain, on 4 April 1997. As of the moment of writing 11 Member States of the EU have ratified the Convention: Cyprus, Czech Republic, Denmark, Estonia, Greece, Hungary, Lithuania, Portugal, Slovakia, Slovenia and Spain. The overall purpose of this article is to analyze whether these ratifying EU Member States have fulfilled their obligation provided for in article 1 of Section 2 of the Convention ("each Party shall take in its internal law the necessary measures to give effect to the provisions of this Convention"). We further explored the legal consequences of ratification of the Convention. We analysed for each ratifying Member State whether and how the ratification of the Convention has influenced patient rights legislation and policies. Finally, we concluded by dividing the 11 Member States into 4 categories depending upon the already existing patient rights legislation at the moment of ratification and the constitutional provisions related to the ratification of an international treaty in general in a given Member State.

  1. A Twist of Principles: Presumption and Burden of Proof in the Virginia Ratification Debates on the Federal Constitution.

    ERIC Educational Resources Information Center

    Einhorn, Lois J.

    1990-01-01

    Examines how the timing of Virginia's Ratification Convention twisted the principles of presumption and burden of proof in favor of the Federalists. Applies Richard Whately's rhetorical constructs to actual debates to analyze rhetorical strategies and voting behavior. Argues the need to modify the meaning of presumption and burden of proof. (KEH)

  2. Addressing the tobacco epidemic in the Philippines: progress since ratification of the WHO FCTC.

    PubMed

    Bellew, B; Antonio, M; Limpin, M; Alzona, L; Trinidad, F; Dorotheo, U; Yapchiongco, R; Garcia, R; Anden, A; Alday, J

    2013-06-21

    Tobacco use is the leading cause of preventable death, and is estimated to kill more than 5 million persons each year worldwide. Tobacco use and exposure to second-hand smoke pose a major public health problem in the Philippines. Effective tobacco control policies are enshrined in the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC), a legally binding international treaty that was ratified by the Philippines in 2005. Since 2007, Bloomberg Philanthropies has supported the accelerated reduction of tobacco use in many countries, including the Philippines. Progress in the Philippines is discussed with particular emphasis on the period since ratification of the WHO FCTC, and with particular focus on the grants programme funded by the Bloomberg Initiative. Despite considerable progress, significant challenges are identified that must be addressed in future if the social, health and economic burden from the tobacco epidemic is to be alleviated.

  3. Addressing the tobacco epidemic in the Philippines: progress since ratification of the WHO FCTC

    PubMed Central

    Antonio, M.; Limpin, M.; Alzona, L.; Trinidad, F.; Dorotheo, U.; Yapchiongco, R.; Garcia, R.; Anden, A.; Alday, J.

    2013-01-01

    Tobacco use is the leading cause of preventable death, and is estimated to kill more than 5 million persons each year worldwide. Tobacco use and exposure to second-hand smoke pose a major public health problem in the Philippines. Effective tobacco control policies are enshrined in the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC), a legally binding international treaty that was ratified by the Philippines in 2005. Since 2007, Bloomberg Philanthropies has supported the accelerated reduction of tobacco use in many countries, including the Philippines. Progress in the Philippines is discussed with particular emphasis on the period since ratification of the WHO FCTC, and with particular focus on the grants programme funded by the Bloomberg Initiative. Despite considerable progress, significant challenges are identified that must be addressed in future if the social, health and economic burden from the tobacco epidemic is to be alleviated. PMID:26393010

  4. Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016).

    PubMed

    Adams, Michael J; Lefkowitz, Elliot J; King, Andrew M Q; Harrach, Balázs; Harrison, Robert L; Knowles, Nick J; Kropinski, Andrew M; Krupovic, Mart; Kuhn, Jens H; Mushegian, Arcady R; Nibert, Max; Sabanadzovic, Sead; Sanfaçon, Hélène; Siddell, Stuart G; Simmonds, Peter; Varsani, Arvind; Zerbini, Francisco Murilo; Gorbalenya, Alexander E; Davison, Andrew J

    2016-10-01

    This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2016.Changes to virus taxonomy (the Universal Scheme of Virus Classification of the International Committee on Taxonomy of Viruses [ICTV]) now take place annually and are the result of a multi-stage process. In accordance with the ICTV Statutes ( http://www.ictvonline.org/statutes.asp ), proposals submitted to the ICTV Executive Committee (EC) undergo a review process that involves input from the ICTV Study Groups (SGs) and Subcommittees (SCs), other interested virologists, and the EC. After final approval by the EC, proposals are then presented for ratification to the full ICTV membership by publication on an ICTV web site ( http://www.ictvonline.org/ ) followed by an electronic vote. The latest set of proposals approved by the EC was made available on the ICTV website by January 2016 ( https://talk.ictvonline.org/files/proposals/ ). A list of these proposals was then emailed on 28 March 2016 to the 148 members of ICTV, namely the EC Members, Life Members, ICTV Subcommittee Members (including the SG chairs) and ICTV National Representatives. Members were then requested to vote on whether to ratify the taxonomic proposals (voting closed on 29 April 2016).

  5. Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016).

    PubMed

    Adams, Michael J; Lefkowitz, Elliot J; King, Andrew M Q; Harrach, Balázs; Harrison, Robert L; Knowles, Nick J; Kropinski, Andrew M; Krupovic, Mart; Kuhn, Jens H; Mushegian, Arcady R; Nibert, Max; Sabanadzovic, Sead; Sanfaçon, Hélène; Siddell, Stuart G; Simmonds, Peter; Varsani, Arvind; Zerbini, Francisco Murilo; Gorbalenya, Alexander E; Davison, Andrew J

    2016-10-01

    This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2016.Changes to virus taxonomy (the Universal Scheme of Virus Classification of the International Committee on Taxonomy of Viruses [ICTV]) now take place annually and are the result of a multi-stage process. In accordance with the ICTV Statutes ( http://www.ictvonline.org/statutes.asp ), proposals submitted to the ICTV Executive Committee (EC) undergo a review process that involves input from the ICTV Study Groups (SGs) and Subcommittees (SCs), other interested virologists, and the EC. After final approval by the EC, proposals are then presented for ratification to the full ICTV membership by publication on an ICTV web site ( http://www.ictvonline.org/ ) followed by an electronic vote. The latest set of proposals approved by the EC was made available on the ICTV website by January 2016 ( https://talk.ictvonline.org/files/proposals/ ). A list of these proposals was then emailed on 28 March 2016 to the 148 members of ICTV, namely the EC Members, Life Members, ICTV Subcommittee Members (including the SG chairs) and ICTV National Representatives. Members were then requested to vote on whether to ratify the taxonomic proposals (voting closed on 29 April 2016). PMID:27424026

  6. Locoregionally Advanced Head and Neck Cancer Treated With Primary Radiotherapy: A Comparison of the Addition of Cetuximab or Chemotherapy and the Impact of Protocol Treatment

    SciTech Connect

    Caudell, Jimmy J.; Sawrie, Stephen M.; Spencer, Sharon A.; Desmond, Renee A.; Carroll, William R.; Peters, Glenn E.; Nabell, Lisle M.; Meredith, Ruby F.; Bonner, James A.

    2008-07-01

    Purpose: The addition of platinum-based chemotherapy (ChRT) or cetuximab (ExRT) to concurrent radiotherapy (RT) has resulted in improved survival in Phase III studies for locoregionally advanced head and neck cancer (LAHNC). However the optimal treatment regimen has not been defined. A retrospective study was performed to compare outcomes in patients who were treated definitively with ExRT or ChRT. Methods: Cetuximab with concurrent RT was used to treat 29 patients with LAHNC, all of whom had tumors of the oral cavity, oropharynx, or larynx. All patients were T2 to T4 and overall American Joint Committee on Cancer Stage III to IVB, with a Karnofsky Performance Status (KPS) score of 60 or greater. ChRT was used to treat 103 patients with similar characteristics. Patients were evaluated for locoregional control (LRC), distant metastasis-free survival (DMFS), disease-specific survival (DSS), and overall survival (OS). Median follow-up for patients alive at last contact was 83 months for those treated with ExRT and 53 months for those treated with ChRT. Cox proportional hazard models were used to assess independent prognostic factors. Results: The LRC, DMFS, and DSS were not significantly different, with 3-year rates of 70.7%, 92.4%, and 78.6% for ExRT and 74.7%, 86.6%, and 76.5% for ChRT, respectively. The OS was significantly different between the two groups (p = 0.02), with 3-year rates of 75.9% for ExRT and 61.3% for ChRT. OS was not significant when patients who were on protocol treatments of ExRT or ChRT were compared. Also, OS was not significant when multivariate analysis was used to control for potential confounding factors. Conclusion: In our single-institution retrospective review of patients treated with ExRT or ChRT, no significant differences were found in LRC, DMFS, DSS, or OS.

  7. Carbon emissions. The economic benefits of the Kyoto Protocol.

    PubMed

    De Leo, G A; Rizzi, L; Caizzi, A; Gatto, M

    2001-10-01

    The third Conference of the Parties in Kyoto set the target of reducing greenhouse-gas emissions by an average of 5.3% with respect to 1990 values by 2008-2012. One of the main objections to the protocol's ratification is that compliance would pose an unbearable economic burden on the countries involved. But we show here that this is not the case if costs apart from the direct costs of energy production are also considered. Costs are also incurred in rectifying damage to human health, material goods, agriculture and the environment related to greenhouse-gas emissions.

  8. NGSI student activities in open source information analysis in support of the training program of the U.S. DOE laboratories for the entry into force of the additional protocol

    SciTech Connect

    Sandoval, M Analisa; Uribe, Eva C; Sandoval, Marisa N; Boyer, Brian D; Stevens, Rebecca S

    2009-01-01

    In 2008 a joint team from Los Alamos National Laboratory (LANL) and Brookhaven National Laboratory (BNL) consisting of specialists in training of IAEA inspectors in the use of complementary access activities formulated a training program to prepare the U.S. Doe laboratories for the entry into force of the Additional Protocol. As a major part of the support of the activity, LANL summer interns provided open source information analysis to the LANL-BNL mock inspection team. They were a part of the Next Generation Safeguards Initiative's (NGSI) summer intern program aimed at producing the next generation of safeguards specialists. This paper describes how they used open source information to 'backstop' the LANL-BNL team's effort to construct meaningful Additional Protocol Complementary Access training scenarios for each of the three DOE laboratories, Lawrence Livermore National Laboratory, Idaho National Laboratory, and Oak Ridge National Laboratory.

  9. U.S. ratification of the CRC and reducing child poverty: can we get there from here?

    PubMed

    Aber, J Lawrence; Hammond, Andrew S; Thompson, Scott M

    2010-01-01

    If the United States finally ratifies the United Nations Convention of the Rights of the Child (CRC), will it improve the country's to effectively combat child poverty and thereby improve child well-being? This article addresses this and related questions in two ways. First, the authors examine how ratification of the CRC has influenced the efforts of other wealthy Anglophone countries to reduce child poverty. Second, they draw on lessons learned from these other countries' efforts to generate predictions about America's postratification future. The authors conclude that, while the CRC is a compelling, practical tool, a communications strategy and business plan are necessary complements to achieve desired results. PMID:21361163

  10. The ADDITION-Cambridge trial protocol: a cluster – randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

    PubMed Central

    Echouffo-Tcheugui, Justin B; Simmons, Rebecca K; Williams, Kate M; Barling, Roslyn S; Prevost, A Toby; Kinmonth, Ann Louise; Wareham, Nicholas J; Griffin, Simon J

    2009-01-01

    Background The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type 2 diabetes could reduce this growing burden. However, the benefits of such a strategy remain uncertain. Methods and design The ADDITION-Cambridge study aims to evaluate the effectiveness and cost-effectiveness of (i) a stepwise screening strategy for type 2 diabetes; and (ii) intensive multifactorial treatment for people with screen-detected diabetes in primary care. 63 practices in the East Anglia region participated. Three undertook the pilot study, 33 were allocated to three groups: no screening (control), screening followed by intensive treatment (IT) and screening plus routine care (RC) in an unbalanced (1:3:3) randomisation. The remaining 27 practices were randomly allocated to IT and RC. A risk score incorporating routine practice data was used to identify people aged 40–69 years at high-risk of undiagnosed diabetes. In the screening practices, high-risk individuals were invited to take part in a stepwise screening programme. In the IT group, diabetes treatment is optimised through guidelines, target-led multifactorial treatment, audit, feedback, and academic detailing for practice teams, alongside provision of educational materials for newly diagnosed participants. Primary endpoints are modelled cardiovascular risk at one year, and cardiovascular mortality and morbidity at five years after diagnosis of diabetes. Secondary endpoints include all-cause mortality, development of renal and visual impairment, peripheral neuropathy, health service costs, self-reported quality of life, functional status and health utility. Impact of the screening programme at the population level is also assessed through measures of mortality, cardiovascular morbidity, health status and health service use among high-risk individuals. Discussion ADDITION-Cambridge is conducted in a defined high-risk group accessible through primary

  11. Communications protocol

    NASA Technical Reports Server (NTRS)

    Zhou, Xiaoming (Inventor); Baras, John S. (Inventor)

    2010-01-01

    The present invention relates to an improved communications protocol which increases the efficiency of transmission in return channels on a multi-channel slotted Alohas system by incorporating advanced error correction algorithms, selective retransmission protocols and the use of reserved channels to satisfy the retransmission requests.

  12. Optimising corticosteroid injection for lateral epicondylalgia with the addition of physiotherapy: A protocol for a randomised control trial with placebo comparison

    PubMed Central

    Coombes, Brooke K; Bisset, Leanne; Connelly, Luke B; Brooks, Peter; Vicenzino, Bill

    2009-01-01

    Background Corticosteroid injection and physiotherapy are two commonly prescribed interventions for management of lateral epicondylalgia. Corticosteroid injections are the most clinically efficacious in the short term but are associated with high recurrence rates and delayed recovery, while physiotherapy is similar to injections at 6 weeks but with significantly lower recurrence rates. Whilst practitioners frequently recommend combining physiotherapy and injection to overcome harmful effects and improve outcomes, study of the benefits of this combination of treatments is lacking. Clinicians are also faced with the paradox that the powerful anti-inflammatory corticosteroid injections work well, albeit in the short term, for a non-inflammatory condition like lateral epicondylalgia. Surprisingly, these injections have not been rigorously tested against placebo injections. This study primarily addresses both of these issues. Methods A randomised placebo-controlled clinical trial with a 2 × 2 factorial design will evaluate the clinical efficacy, cost-effectiveness and recurrence rates of adding physiotherapy to an injection. In addition, the clinical efficacy and adverse effects of corticosteroid injection beyond that of a placebo saline injection will be studied. 132 participants with a diagnosis of lateral epicondylalgia will be randomly assigned by concealed allocation to one of four treatment groups – corticosteroid injection, saline injection, corticosteroid injection with physiotherapy or saline injection with physiotherapy. Physiotherapy will comprise 8 sessions of elbow manipulation and exercise over an 8 week period. Blinded follow-up assessments will be conducted at baseline, 4, 8, 12, 26 and 52 weeks after randomisation. The primary outcome will be a participant rating of global improvement, from which measures of success and recurrence will be derived. Analyses will be conducted on an intention-to-treat basis using linear mixed and logistic regression

  13. [International regulation of ethics committees on biomedical research as protection mechanisms for people: analysis of the Additional Protocol to the Convention on Human Rights and Biomedicine, concerning Biomedical Research of the Council of Europe].

    PubMed

    de Lecuona, Itziar

    2013-01-01

    The article explores and analyses the content of the Council of Europe's Additional Protocol to the Convention on Human Rights and Biomedicine concerning Biomedical Research regarding the standard legal instrument in biomedical research, issued by an international organization with leadership in bioethics. This implies ethics committees are mechanisms of protection of humans in biomedical research and not mere bureaucratic agencies and that a sound inescapable international regulatory framework exists for States to regulate biomedical research. The methodology used focuses on the analysis of the background, the context in which it is made and the nature and scope of the Protocol. It also identifies and analyses the characteristics and functions of ethics committees in biomedical research and, in particular, the information that should be provided to this bodies to develop their functions previously, during and at the end of research projects. This analysis will provide guidelines, suggestions and conclusions for the awareness and training of members of these committees in order to influence the daily practice. This paper may also be of interest to legal practitioners who work in different areas of biomedical research. From this practical perspective, the article examines the legal treatment of the Protocol to meet new challenges and classic issues in research: the treatment of human biological samples, the use of placebos, avoiding double standards, human vulnerability, undue influence and conflicts of interest, among others. Also, from a critical view, this work links the legal responses to develop work procedures that are required for an effective performance of the functions assigned of ethics committees in biomedical research. An existing international legal response that lacks doctrinal standards and provides little support should, however, serve as a guide and standard to develop actions that allow ethics committees -as key bodies for States- to advance in

  14. Satellite Communications Using Commercial Protocols

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.; Griner, James H.; Dimond, Robert; Frantz, Brian D.; Kachmar, Brian; Shell, Dan

    2000-01-01

    NASA Glenn Research Center has been working with industry, academia, and other government agencies in assessing commercial communications protocols for satellite and space-based applications. In addition, NASA Glenn has been developing and advocating new satellite-friendly modifications to existing communications protocol standards. This paper summarizes recent research into the applicability of various commercial standard protocols for use over satellite and space- based communications networks as well as expectations for future protocol development. It serves as a reference point from which the detailed work can be readily accessed. Areas that will be addressed include asynchronous-transfer-mode quality of service; completed and ongoing work of the Internet Engineering Task Force; data-link-layer protocol development for unidirectional link routing; and protocols for aeronautical applications, including mobile Internet protocol routing for wireless/mobile hosts and the aeronautical telecommunications network protocol.

  15. Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: Pipeline Pilot protocols, xls file with the output of the Pipeline Pilot protocols, KNIME workflows, and supplementary figures showing the Pipeline Pilot protocols. See DOI: 10.1039/c6md00065g Click here for additional data file.

    PubMed Central

    Zdrazil, B.; Neefs, J.-M.; Van Vlijmen, H.; Herhaus, C.; Caracoti, A.; Brea, J.; Roibás, B.; Loza, M. I.; Queralt-Rosinach, N.; Furlong, L. I.; Gaulton, A.; Bartek, L.; Senger, S.; Chichester, C.; Engkvist, O.; Evelo, C. T.; Franklin, N. I.; Marren, D.; Ecker, G. F.

    2016-01-01

    Phenotypic screening is in a renaissance phase and is expected by many academic and industry leaders to accelerate the discovery of new drugs for new biology. Given that phenotypic screening is per definition target agnostic, the emphasis of in silico and in vitro follow-up work is on the exploration of possible molecular mechanisms and efficacy targets underlying the biological processes interrogated by the phenotypic screening experiments. Herein, we present six exemplar computational protocols for the interpretation of cellular phenotypic screens based on the integration of compound, target, pathway, and disease data established by the IMI Open PHACTS project. The protocols annotate phenotypic hit lists and allow follow-up experiments and mechanistic conclusions. The annotations included are from ChEMBL, ChEBI, GO, WikiPathways and DisGeNET. Also provided are protocols which select from the IUPHAR/BPS Guide to PHARMACOLOGY interaction file selective compounds to probe potential targets and a correlation robot which systematically aims to identify an overlap of active compounds in both the phenotypic as well as any kinase assay. The protocols are applied to a phenotypic pre-lamin A/C splicing assay selected from the ChEMBL database to illustrate the process. The computational protocols make use of the Open PHACTS API and data and are built within the Pipeline Pilot and KNIME workflow tools. PMID:27774140

  16. Optimisation thermique de moules d'injection construits par des processus génératifs

    NASA Astrophysics Data System (ADS)

    Boillat, E.; Glardon, R.; Paraschivescu, D.

    2002-12-01

    Une des potentialités les plus remarquables des procédés de production génératifs, comme le frittage sélectif par laser, est leur capacité à fabriquer des moules pour l'injection plastique équipés directement de canaux de refroidissement conformes, parfaitement adaptés aux empreintes Pour que l'industrie de l'injection puisse tirer pleinement parti de cette nouvelle opportunité, il est nécessaire de mettre à la disposition des moulistes des logiciels de simulation capables d'évaluer les gains de productivité et de qualité réalisables avec des systèmes de refroidissement mieux adaptés. Ces logiciels devraient aussi être capables, le cas échéant, de concevoir le système de refroidissement optimal dans des situations où l'empreinte d'injection est complexe. Devant le manque d'outils disponibles dans ce domaine, le but de cet article est de proposer un modèle simple de moules d'injection. Ce modèle permet de comparer différentes stratégies de refroidissement et peut être couplé avec un algorithme d'optimisation.

  17. The efficacy of the addition of the Pilates method over a minimal intervention in the treatment of chronic nonspecific low back pain: a study protocol of a randomized controlled trial☆

    PubMed Central

    Miyamoto, Gisela C.; Costa, Leonardo O.P.; Galvanin, Thalissa; Cabral, Cristina M.N.

    2011-01-01

    Objective There is little high-quality evidence on the efficacy of the Pilates-based exercises for the treatment of chronic nonspecific low back pain. Therefore, the objective of this paper is to present a study protocol to investigate the efficacy of adding Pilates-based exercises to a minimum intervention in patients with chronic non-specific low back pain. Methods This randomized controlled trial will recruit 86 patients of both sexes, aged between 18 and 60 years, with chronic non-specific low back pain. The participants will be randomly allocated into 2 treatment groups: the Booklet Group, which will receive a booklet with postural orientations, and the Pilates Group, which will receive the same booklet in addition to a Pilates-based exercises program. The general and specific functional capacities of the patient, kinesiophobia, pain intensity, and the global perceived effect will be evaluated by a blinded assessor before randomization and at 6 weeks and 6 months after randomization. In addition, the expectations of the participants and their confidence in the treatment will be evaluated before the randomization and after the first treatment session, respectively. Conclusions It is hoped that the results of this study will provide high-quality evidence on the usefulness of Pilates-based exercises in the treatment of chronic non-specific low back pain. PMID:22654682

  18. Rational Protocols

    NASA Astrophysics Data System (ADS)

    Cachin, Christian

    Security research continues to provide a plethora of new protocols and mechanisms; these solutions patch either existing vulnerabilities found in practical systems or solve hypothetical security problems in the sense that the problem is often conceived at the same time when the first solution is proposed. Yet only a very small fraction of this research is relevant to ordinary users in the sense that they are willing to actually deploy the technology.

  19. A study protocol of a randomised controlled trial incorporating a health economic analysis to investigate if additional allied health services for rehabilitation reduce length of stay without compromising patient outcomes

    PubMed Central

    2010-01-01

    controlled trial. Discussion This paper outlines the study protocol for the first fully powered randomised controlled trial incorporating a health economic analysis to establish if additional Saturday allied health services for rehabilitation inpatients reduces length of stay without compromising discharge outcomes. If successful, this trial will have substantial health benefits for the patients and for organizations delivering rehabilitation services. Clinical trial registration number Australian and New Zealand Clinical Trials Registry ACTRN12609000973213 PMID:21073703

  20. Indoor air quality investigation protocols

    SciTech Connect

    Greene, R.E.; Williams, P.L.

    1996-10-01

    Over the past 10 to 15 years, an increasing number of complaints about discomfort and health effects related to indoor air quality (IAQ) have been reported. The increase in complaints has been accompanied by an increase in requests for IAQ investigations. This study presents an overview of the many IAQ investigation protocols published since 1984. For analysis, the protocols are divided into four categories: solution-oriented, building diagnostics, industrial hygiene, and epidemiology. In general, the protocols begin with general observations, proceed to collect more specific data as indicated, and end with conclusions and recommendations. A generic IAQ protocol is presented that incorporates the common aspects of the various protocols. All of the current protocols place heavy emphasis on the ventilation system during the investigation. A major problem affecting all of the current protocols is the lack of generally accepted IAQ standards. IN addition, the use of questionnaires, occupant interviews, and personal diaries (as well as the point in the investigation at which they are administered) differs among the protocols. Medical evaluations and verification procedures also differ among the protocols.

  1. Nonblocking and orphan free message logging protocols

    NASA Technical Reports Server (NTRS)

    Alvisi, Lorenzo; Hoppe, Bruce; Marzullo, Keith

    1992-01-01

    Currently existing message logging protocols demonstrate a classic pessimistic vs. optimistic tradeoff. We show that the optimistic-pessimistic tradeoff is not inherent to the problem of message logging. We construct a message-logging protocol that has the positive features of both optimistic and pessimistic protocol: our protocol prevents orphans and allows simple failure recovery; however, it requires no blocking in failure-free runs. Furthermore, this protocol does not introduce any additional message overhead as compared to one implemented for a system in which messages may be lost but processes do not crash.

  2. Mars Communication Protocols

    NASA Technical Reports Server (NTRS)

    Kazz, G. J.; Greenberg, E.

    2000-01-01

    Over the next decade, international plans and commitments are underway to develop an infrastructure at Mars to support future exploration of the red planet. The purpose of this infrastructure is to provide reliable global communication and navigation coverage for on-approach, landed, roving, and in-flight assets at Mars. The claim is that this infrastructure will: 1) eliminate the need of these assets to carry Direct to Earth (DTE) communications equipment, 2) significantly increase data return and connectivity, 3) enable small mission exploration of Mars without DTE equipment, 4) provide precision navigation i.e., 10 to 100m position resolution, 5) supply timing reference accurate to 10ms. This paper in particular focuses on two CCSDS recommendations for that infrastructure: CCSDS Proximity-1 Space Link Protocol and CCSDS File Delivery Protocol (CFDP). A key aspect of Mars exploration will be the ability of future missions to interoperate. These protocols establish a framework for interoperability by providing standard communication, navigation, and timing services. In addition, these services include strategies to recover gracefully from communication interruptions and interference while ensuring backward compatibility with previous missions from previous phases of exploration.

  3. Delay Tolerant Networking - Bundle Protocol Simulation

    NASA Technical Reports Server (NTRS)

    SeGui, John; Jenning, Esther

    2006-01-01

    In this paper, we report on the addition of MACHETE models needed to support DTN, namely: the Bundle Protocol (BP) model. To illustrate the useof MACHETE with the additional DTN model, we provide an example simulation to benchmark its performance. We demonstrate the use of the DTN protocol and discuss statistics gathered concerning the total time needed to simulate numerous bundle transmissions.

  4. [Diagnostic protocol and special tests].

    PubMed

    Bellia, M; Pennarola, R

    2008-01-01

    Diagnostic protocol and special tests to ionizing radiations have a preventive function in the medical surveillance of the exposed worker. This protocol must be provided with laboratory and special test assessing fitness for working at the risk of ionizing radiations. The health of workers must be compatible with working conditions and radiation risk. This healthiness of workers is evalued in the time to give an assessment fitness for working at ionizing radiations. For this purpose the basic diagnostic protocol must guarantee minimum information about state of organs and apparatus in addition to the normality of the metabolisms. The diagnostic protocol of the exposed worker to ionizing radiations must be adapted to the specific clinical situation so as to finally make a costs-benefits balance sheet. PMID:19288808

  5. Effective Protocols for Mobile Communications and Networking

    SciTech Connect

    Espinoza, J.; Sholander, P.; Van Leeuwen, B,

    1998-12-01

    This report examines methods of mobile communications with an emphasis on mobile computing and wireless communications. Many of the advances in communications involve the use of Internet Protocol (IP), Asynchronous Transfer Mode (ATM), and ad hoc network protocols. However, many of the advances in these protocols have been focused on wired communications. Recently much focus has been directed at advancing communication technology in the area of mobile wireless networks. This report discusses various protocols used in mobile communications and proposes a number of extensions to existing protocols. A detailed discussion is also included on desirable protocol characteristics and evaluation criteria. In addition, the report includes a discussion on several network simulation tools that maybe used to evaluate network protocols.

  6. Methow and Columbia Rivers studies: summary of data collection, comparison of database structure and habitat protocols, and impact of additional PIT tag interrogation systems to survival estimates, 2008-2012

    USGS Publications Warehouse

    Martens, Kyle D.; Tibbits, Wesley T.; Watson, Grace A.; Newsom, Michael A.; Connolly, Patrick J.

    2014-01-01

    designed to show some initial analysis and to disseminate summary information that could potentially be used in ongoing modeling efforts by USGS, Reclamation, and University of Idaho. The second chapter documents the database of fish and habitat data collected by USGS from 2004 through 2012 and compares USGS habitat protocols to the Columbia Habitat Monitoring Program (CHaMP) protocol. The third chapter is a survival analysis of fish moving through Passive Integrated Transponder (PIT) tag interrogation systems in the Methow and Columbia Rivers. It examines the effects of adding PIT tags and/or PIT tag interrogation systems on survival estimates of juvenile steelhead and Chinook salmon.

  7. Licklider Transmission Protocol Implementation

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.; Krupiarz, Chris

    2011-01-01

    This software is an implementation of the Licklider Transmission Protocol (LTP), a communications protocol intended to support the Bundle Protocol in Delay-Tolerant Network (DTN) operations. LTP is designed to provide retransmission-based reliability over links characterized by extremely long message round-trip times and/or frequent interruptions in connectivity. Communication in interplanetary space is the most prominent example of this sort of environment, and LTP is principally aimed at supporting long-haul reliable transmission over deep-space RF links. Like any reliable transport service employing ARQ (Automatic Repeat re-Quests), LTP is stateful. In order to assure the reception of a block of data it has sent, LTP must retain for possible retransmission all portions of that block which might not have been received yet. In order to do so, it must keep track of which portions of the block are known to have been received so far, and which are not, together with any additional information needed for purposes of retransmitting part, or all, of the block. Long round-trip times mean substantial delay between the transmission of a block of data and the reception of an acknowledgement from the block s destination, signaling arrival of the block. If LTP postponed transmission of additional blocks of data until it received acknowledgement of the arrival of all prior blocks, valuable opportunities to use what little deep space transmission bandwidth is available would be forever lost. For this reason, LTP is based in part on a notion of massive state retention. Any number of requested transmission conversations (sessions) may be concurrently in flight at various displacements along the link between two LTP engines, and the LTP engines must necessarily retain transmission status and retransmission resources for all of them. Moreover, if any of the data of a given block are lost en route, it will be necessary to retain the state of that transmission during an additional

  8. Economic analysis of a phase III clinical trial evaluating the addition of total androgen suppression to radiation versus radiation alone for locally advanced prostate cancer (Radiation Therapy Oncology Group protocol 86-10)

    SciTech Connect

    Konski, Andre . E-mail: a_konski@fccc.edu; Sherman, Eric; Krahn, Murray; Bremner, Karen; Beck, J. Robert; Watkins-Bruner, Deborah; Pilepich, Michael

    2005-11-01

    Purpose: To evaluate the cost-effectiveness of adding hormone therapy to radiation for patients with locally advanced prostate cancer, using a Monte Carlo simulation of a Markov Model. Methods and Materials: Radiation Therapy Oncology Group (RTOG) protocol 86-10 randomized patients to receive radiation therapy (RT) alone or RT plus total androgen suppression (RTHormones) 2 months before and during RT for the treatment of locally advanced prostate cancer. A Markov model was designed with Data Pro (TreeAge Software, Williamstown, MA). The analysis took a payer's perspective. Transition probabilities from one state of health (i.e., with no disease progression or with hormone-responsive metastatic disease) to another were calculated from published rates pertaining to RTOG 86-10. Patients remained in one state of health for 1 year. Utility values for each health state and treatment were obtained from the literature. Distributions were sampled at random from the treatment utilities according to a second-order Monte Carlo simulation technique. Results: The mean expected cost for the RT-only treatments was $29,240 (range, $29,138-$29,403). The mean effectiveness for the RT-only treatment was 5.48 quality-adjusted life years (QALYs) (range, 5.47-5.50). The mean expected cost for RTHormones was $31,286 (range, $31,058-$31,555). The mean effectiveness was 6.43 QALYs (range, 6.42-6.44). Incremental cost-effectiveness analysis showed RTHormones to be within the range of cost-effectiveness at $2,153/QALY. Cost-effectiveness acceptability curve analysis resulted in a >80% probability that RTHormones is cost-effective. Conclusions: Our analysis shows that adding hormonal treatment to RT improves health outcomes at a cost that is within the acceptable cost-effectiveness range.

  9. Alternative parallel ring protocols

    NASA Technical Reports Server (NTRS)

    Mukkamala, R.; Foudriat, E. C.; Maly, Kurt J.; Kale, V.

    1990-01-01

    Communication protocols are know to influence the utilization and performance of communication network. The effect of two token ring protocols on a gigabit network with multiple ring structure is investigated. In the first protocol, a mode sends at most one message on receiving a token. In the second protocol, a mode sends all the waiting messages when a token is received. The behavior of these protocols is shown to be highly dependent on the number of rings as well as the load in the network.

  10. Training program to prepare the U.S. DOE laboratories for the entry into force of the protocol additional to the agreement between the United States of America and the International Atomic Energy Agency for the application of safeguards in the United

    SciTech Connect

    Boyer, Brian David; Stevens, Rebecca C; Uribe, Eva C; Sandoval, M Analisa; Valente, John N; Valente, John U; Jo, Jae H; Sellen, Joana

    2009-01-01

    In 2008, a joint team from Brookhaven National Laboratory (BNL) and Los Alamos National Laboratory (LANL) consisting of specialists in training IAEA inspectors in the use of complementary access activities formulated a training program to prepare the U.S DOE laboratories for the entry into force of the U.S. Additional Protocol. Since the U.S. Additional Protocol would allow for IAEA access to the DOE laboratories under the aegis of complementary access activities, the DOE laboratories would need to prepare for such visits. The goal of the training was to ensure that the DOE laboratories would successfully host an IAEA complementary access. In doing so, the labs must be able to provide the IAEA with the information that the IAEA would need to resolve its questions about the U.S. Declaration and declared activities at the lab, and also protect certain equities, as provided under the U.S. Additional Protocol Article 1.b and c. which set forth a 'National Security Exclusion.' This 'NSE' states that the AP provisions apply within the United States 'excluding only instances where its application would result in access by the Agency to activities with direct national security significance to the United States or to location or information associated with such activities.' These activities are referred to collectively as DNSS-direct national security significance. Furthermore, the U.S. has a specific right to employ managed access, without prejudice to the right under Article 1.b, in connection with activities of DNSS. The provisions in Articles 1.b and 1.c are unique to the U.S. AP, and are additional to the more general right, under Article 7, to use managed access to protect from disclosure proprietary and/or proliferation-sensitive information, and to meet safety and security requirements, that is incorporated directly from the Model Additional Protocol. The BNL-LANL team performed training at Lawrence Livermore National Laboratory, Idaho National Laboratory, and Oak

  11. To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised trial

    PubMed Central

    2011-01-01

    Background Recently, there has been mounting interest in scaling-up vector control against malaria in Africa. It needs to be determined if indoor residual spraying (IRS with DDT) will provide significant marginal protection against malaria over current best practice of long-lasting insecticidal nets (LLINs) and prompt treatment in a controlled trial, given that DDT is currently the most persistent insecticide for IRS. Methods A 2 armed cluster-randomised controlled trial will be conducted to assess whether DDT IRS and LLINs combined provide better protection against clinical malaria in children than LLINs alone in rural Gambia. Each cluster will be a village, or a group of small adjacent villages; all clusters will receive LLINs and half will receive IRS in addition. Study children, aged 6 months to 13 years, will be enrolled from all clusters and followed for clinical malaria using passive case detection to estimate malaria incidence for 2 malaria transmission seasons in 2010 and 2011. This will be the primary endpoint. Exposure to malaria parasites will be assessed using light and exit traps followed by detection of Anopheles gambiae species and sporozoite infection. Study children will be surveyed at the end of each transmission season to estimate the prevalence of Plasmodium falciparum infection and the prevalence of anaemia. Discussion Practical issues concerning intervention implementation, as well as the potential benefits and risks of the study, are discussed. Trial Registration ISRCTN01738840 - Spraying And Nets Towards malaria Elimination (SANTE) PMID:21663656

  12. Food additives

    PubMed Central

    Spencer, Michael

    1974-01-01

    Food additives are discussed from the food technology point of view. The reasons for their use are summarized: (1) to protect food from chemical and microbiological attack; (2) to even out seasonal supplies; (3) to improve their eating quality; (4) to improve their nutritional value. The various types of food additives are considered, e.g. colours, flavours, emulsifiers, bread and flour additives, preservatives, and nutritional additives. The paper concludes with consideration of those circumstances in which the use of additives is (a) justified and (b) unjustified. PMID:4467857

  13. The RTS2 protocol

    NASA Astrophysics Data System (ADS)

    Kubánek, Petr; Jelínek, Martin; French, John; Prouza, Michal; Vítek, Stanislav; Castro-Tirado, Alberto J.; Reglero, Victor

    2008-07-01

    Remote Telescope System 2nd version (RTS2) is an open source project aimed at developing a software environment to control a fully robotic observatory. RTS2 consists of various components, which communicate via an ASCII based protocol. As the protocol was from the beginning designed as an observatory control system, it provides some unique features, which are hard to find in the other communication systems. These features include advanced synchronisation mechanisms and strategies for setting variables. This presentation describes the protocol and its unique features. It also assesses protocol performance, and provides examples how the RTS2 library can be used to quickly build an observatory control system.

  14. Military veterans with mental health problems: a protocol for a systematic review to identify whether they have an additional risk of contact with criminal justice systems compared with other veterans groups

    PubMed Central

    2012-01-01

    Background There is concern that some veterans of armed forces, in particular those with mental health, drug or alcohol problems, experience difficulty returning to a civilian way of life and may subsequently come into contact with criminal justice services and imprisonment. The aim of this review is to examine whether military veterans with mental health problems, including substance use, have an additional risk of contact with criminal justice systems when compared with veterans who do not have such problems. The review will also seek to identify veterans’ views and experiences on their contact with criminal justice services, what contributed to or influenced their contact and whether there are any differences, including international and temporal, in incidence, contact type, veteran type, their presenting health needs and reported experiences. Methods/design In this review we will adopt a methodological model similar to that previously used by other researchers when reviewing intervention studies. The model, which we will use as a framework for conducting a review of observational and qualitative studies, consists of two parallel synthesis stages within the review process; one for quantitative research and the other for qualitative research. The third stage involves a cross study synthesis, enabling a deeper understanding of the results of the quantitative synthesis. A range of electronic databases, including MEDLINE, PsychINFO, CINAHL, will be systematically searched, from 1939 to present day, using a broad range of search terms that cover four key concepts: mental health, military veterans, substance misuse, and criminal justice. Studies will be screened against topic specific inclusion/exclusion criteria and then against a smaller subset of design specific inclusion/exclusion criteria. Data will be extracted for those studies that meet the inclusion criteria, and all eligible studies will be critically appraised. Included studies, both quantitative and

  15. National Sample Assessment Protocols

    ERIC Educational Resources Information Center

    Ministerial Council on Education, Employment, Training and Youth Affairs (NJ1), 2012

    2012-01-01

    These protocols represent a working guide for planning and implementing national sample assessments in connection with the national Key Performance Measures (KPMs). The protocols are intended for agencies involved in planning or conducting national sample assessments and personnel responsible for administering associated tenders or contracts,…

  16. Montreal protocol: Business opportunites

    SciTech Connect

    1998-12-31

    The Montreal Protocol on Substances that Deplete the Ozone Layer was signed by 24 countries in 1987, establishing measures for controlling the production and consumption of ozone-depleting substances. This publication begins with some background information on ozone depletion and the history of the Protocol. It then describes aspects of the Protocol`s Multilateral Fund, created to assist developing countries to meet Protocol deadlines: Its administration, structure, and how projects are initiated. Names, addresses, and phone/fax numbers of Fund contacts are provided. Canadian projects under the Fund are then reviewed and opportunities for Canadian environmental companies are noted. Finally, information sheets are presented which summarize Fund-related Canadian bilateral projects undertaken to date.

  17. Reliable broadcast protocols

    NASA Technical Reports Server (NTRS)

    Joseph, T. A.; Birman, Kenneth P.

    1989-01-01

    A number of broadcast protocols that are reliable subject to a variety of ordering and delivery guarantees are considered. Developing applications that are distributed over a number of sites and/or must tolerate the failures of some of them becomes a considerably simpler task when such protocols are available for communication. Without such protocols the kinds of distributed applications that can reasonably be built will have a very limited scope. As the trend towards distribution and decentralization continues, it will not be surprising if reliable broadcast protocols have the same role in distributed operating systems of the future that message passing mechanisms have in the operating systems of today. On the other hand, the problems of engineering such a system remain large. For example, deciding which protocol is the most appropriate to use in a certain situation or how to balance the latency-communication-storage costs is not an easy question.

  18. Broadening and Simplifying the First SETI Protocol

    NASA Astrophysics Data System (ADS)

    Michaud, M. A. G.

    The Declaration of Principles Concerning Activities Following the Detection of Extraterrestrial Intelligence, known informally as the First SETI Protocol, is the primary existing international guidance on this subject. During the fifteen years since the document was issued, several people have suggested revisions or additional protocols. This article proposes a broadened and simplified text that would apply to the detection of alien technology in our solar system as well as to electromagnetic signals from more remote sources.

  19. Reliable multicast protocol specifications protocol operations

    NASA Technical Reports Server (NTRS)

    Callahan, John R.; Montgomery, Todd; Whetten, Brian

    1995-01-01

    This appendix contains the complete state tables for Reliable Multicast Protocol (RMP) Normal Operation, Multi-RPC Extensions, Membership Change Extensions, and Reformation Extensions. First the event types are presented. Afterwards, each RMP operation state, normal and extended, is presented individually and its events shown. Events in the RMP specification are one of several things: (1) arriving packets, (2) expired alarms, (3) user events, (4) exceptional conditions.

  20. Per-packet reservation MAC protocols

    NASA Astrophysics Data System (ADS)

    Hrasnica, Halid

    2006-10-01

    Recent and future communications networks have to provide QoS guarantees for a rapidly growing number of various telecommunications services. Therefore, various communications systems, such as wireless and fixed access networks, apply reservation MAC protocols, providing a good network utilization, which is particularly important access networks with typically limited data rates, and ensuring realization of different QoS guarantees for various telecommunications services. This is important because of a hard competition among communications technologies applied in the access area. The considered MAC protocols apply a per-packet reservation method to avoid the transmission gaps caused by per-burst reservation, and accordingly to achieve a better network utilization. However, the per-packet reservation increases the network load caused by the signaling, which calls for an efficient resource sharing strategy in the signaling channel. There are two basic solutions for capacity sharing in the signaling channel: random access, usually using slotted ALOHA, and dedicated access, realized by a polling method. Performance improvement of basic protocols can be carried out in different ways; by protocol extensions, a combination of different protocol solutions, and the application of adaptive protocols providing a change of access parameters according to the current network status. The best network performance is achieved by application of two-step reservation protocol, which combined with additional features, such as appropriate signaling procedure, priority and fairness mechanisms, and combined reservation domains, can fulfill requirements of services with high QoS demands.

  1. Phosphazene additives

    DOEpatents

    Harrup, Mason K; Rollins, Harry W

    2013-11-26

    An additive comprising a phosphazene compound that has at least two reactive functional groups and at least one capping functional group bonded to phosphorus atoms of the phosphazene compound. One of the at least two reactive functional groups is configured to react with cellulose and the other of the at least two reactive functional groups is configured to react with a resin, such as an amine resin of a polycarboxylic acid resin. The at least one capping functional group is selected from the group consisting of a short chain ether group, an alkoxy group, or an aryloxy group. Also disclosed are an additive-resin admixture, a method of treating a wood product, and a wood product.

  2. Potlining Additives

    SciTech Connect

    Rudolf Keller

    2004-08-10

    In this project, a concept to improve the performance of aluminum production cells by introducing potlining additives was examined and tested. Boron oxide was added to cathode blocks, and titanium was dissolved in the metal pool; this resulted in the formation of titanium diboride and caused the molten aluminum to wet the carbonaceous cathode surface. Such wetting reportedly leads to operational improvements and extended cell life. In addition, boron oxide suppresses cyanide formation. This final report presents and discusses the results of this project. Substantial economic benefits for the practical implementation of the technology are projected, especially for modern cells with graphitized blocks. For example, with an energy savings of about 5% and an increase in pot life from 1500 to 2500 days, a cost savings of $ 0.023 per pound of aluminum produced is projected for a 200 kA pot.

  3. Routing protocols in wireless sensor networks.

    PubMed

    Villalba, Luis Javier García; Orozco, Ana Lucila Sandoval; Cabrera, Alicia Triviño; Abbas, Cláudia Jacy Barenco

    2009-01-01

    The applications of wireless sensor networks comprise a wide variety of scenarios. In most of them, the network is composed of a significant number of nodes deployed in an extensive area in which not all nodes are directly connected. Then, the data exchange is supported by multihop communications. Routing protocols are in charge of discovering and maintaining the routes in the network. However, the appropriateness of a particular routing protocol mainly depends on the capabilities of the nodes and on the application requirements. This paper presents a review of the main routing protocols proposed for wireless sensor networks. Additionally, the paper includes the efforts carried out by Spanish universities on developing optimization techniques in the area of routing protocols for wireless sensor networks. PMID:22291515

  4. Routing Protocols in Wireless Sensor Networks

    PubMed Central

    Villalba, Luis Javier García; Orozco, Ana Lucila Sandoval; Cabrera, Alicia Triviño; Abbas, Cláudia Jacy Barenco

    2009-01-01

    The applications of wireless sensor networks comprise a wide variety of scenarios. In most of them, the network is composed of a significant number of nodes deployed in an extensive area in which not all nodes are directly connected. Then, the data exchange is supported by multihop communications. Routing protocols are in charge of discovering and maintaining the routes in the network. However, the appropriateness of a particular routing protocol mainly depends on the capabilities of the nodes and on the application requirements. This paper presents a review of the main routing protocols proposed for wireless sensor networks. Additionally, the paper includes the efforts carried out by Spanish universities on developing optimization techniques in the area of routing protocols for wireless sensor networks. PMID:22291515

  5. Climate change in Latin America and the Caribbean. A review of the Bonn and Marrakech decisions and their effect on the clean development mechanism of the Kyoto protocol

    SciTech Connect

    Maggiora, C. della

    2002-04-01

    The objective of this document is to present an overview of recent climate change developments, in particular with regards to carbon markets under the Clean Development Mechanism (CDM). The document is divided into three sections. The first section describes the history of the climate change negotiations. Section two presents an overview of the recent decisions adopted at the last international meetings (Bonn Agreements and Marrakech Accord), which have improved the odds of ratification of the Kyoto Protocol by 2002. The third section analyzes the carbon credit market. The first part of this section briefly presents the available information regarding real carbon credit transactions, while the second section focuses on the literature review of several theoretical models and presents the theoretical estimates of the price and size of the carbon market.

  6. Precise clock synchronization protocol

    NASA Astrophysics Data System (ADS)

    Luit, E. J.; Martin, J. M. M.

    1993-12-01

    A distributed clock synchronization protocol is presented which achieves a very high precision without the need for very frequent resynchronizations. The protocol tolerates failures of the clocks: clocks may be too slow or too fast, exhibit omission failures and report inconsistent values. Synchronization takes place in synchronization rounds as in many other synchronization protocols. At the end of each round, clock times are exchanged between the clocks. Each clock applies a convergence function (CF) to the values obtained. This function estimates the difference between its clock and an average clock and corrects its clock accordingly. Clocks are corrected for drift relative to this average clock during the next synchronization round. The protocol is based on the assumption that clock reading errors are small with respect to the required precision of synchronization. It is shown that the CF resynchronizes the clocks with high precision even when relatively large clock drifts are possible. It is also shown that the drift-corrected clocks remain synchronized until the end of the next synchronization round. The stability of the protocol is proven.

  7. Variable bandwidth broadcasting protocol for video-on-demand

    NASA Astrophysics Data System (ADS)

    Paris, Jehan-Francois; Long, Darrell D. E.

    2003-01-01

    We present the first broadcasting protocol that can alter the number of channels allocated to a given video without inconveniencing the viewer and without causing any temporary bandwidth surge. Our variable bandwidth broadcasting (VBB) protocol assigns to each video a minimum number of channels whose bandwidths are all equal to the video consumption rate. Additional channels can be assigned to the video at any time to reduce the customer waiting time or retaken to free server bandwidth. The cost of this additional flexibility is quite reasonable as the bandwidth requirements of our VBB fall between those of the fast broadcasting protocol and the new pagoda broadcasting protocol.

  8. InterGroup Protocols

    2003-04-02

    Existing reliable ordered group communication protocols have been developed for local-area networks and do not in general scale well to a large number of nodes and wide-area networks. The InterGroup suite of protocols is a scalable group communication system that introduces an unusual approach to handling group membership, and supports a receiver-oriented selection of service. The protocols are intended for a wide-area network, with a large number of nodes, that has highly variable delays andmore » a high message loss rate, such as the Internet. The levels of the message delivery service range from unreliable unordered to reliable timestamp ordered.« less

  9. Minority Languages of the Russian Federation: Perspectives for a Ratification of the European Charter of Regional and Minority Languages. Mercator Working Papers = Las lenguas minoritarias de la Federacion Rusa Perspectivas para una ratificacion de la Carta Europea de las Lenguas Regionales y Minoritarias. Mercator Documentos de trabajo.

    ERIC Educational Resources Information Center

    Vieytez, Eduardo J. Ruiz

    This paper describes the linguistic plurality of the Russian Federation, assessing the impact that the hypothetical ratification of the European Charter of Regional and Minority Languages could have on it. Four sections focus on the following: (1) "Introduction"; (2) "Part 1--The Linguistic Plurality of the Russian Federation": the linguistic…

  10. Formal Analysis of Two Buyer-Seller Watermarking Protocols

    NASA Astrophysics Data System (ADS)

    Williams, David M.; Treharne, Helen; Ho, Anthony T. S.; Waller, Adrian

    In this paper we demonstrate how the formal model constructed in our previous work [1], can be modified in order to analyse additional Buyer-Seller Watermarking Protocols, identifying which specific sections of the CSP scripts remain identical and which require modification. First, we model the protocol proposed by Memon and Wong [2], an examplar of the Offline Watermarking Authority (OFWA) Model, defined in the framework by Poh and Martin [3]. Second, we model the Shao protocol [4] as an example of a protocol fitting the Online Watermarking Authority (ONWA) Model. Our analysis of the protocols reaffirms the unbinding attack described by Lei et al.[5] on the Memon and Wong protocol and we identify a new unbinding attack on the protocol proposed by Shao.

  11. Optimal protocols for nonlocality distillation

    SciTech Connect

    Hoeyer, Peter; Rashid, Jibran

    2010-10-15

    Forster et al. recently showed that weak nonlocality can be amplified by giving the first protocol that distills a class of nonlocal boxes (NLBs) [Phys. Rev. Lett. 102, 120401 (2009)] We first show that their protocol is optimal among all nonadaptive protocols. We next consider adaptive protocols. We show that the depth-2 protocol of Allcock et al. [Phys. Rev. A 80, 062107 (2009)] performs better than previously known adaptive depth-2 protocols for all symmetric NLBs. We present a depth-3 protocol that extends the known region of distillable NLBs. We give examples of NLBs for which each of the Forster et al., the Allcock et al., and our protocols perform best. The understanding we develop is that there is no single optimal protocol for NLB distillation. The choice of which protocol to use depends on the noise parameters for the NLB.

  12. WOODSTOVE DURABILITY TESTING PROTOCOL

    EPA Science Inventory

    The report discusses the development of an accelerated laboratory test to simulate in-home woodstove aging and degradation. nown as a stress test, the protocol determines the long-term durability of woodstove models in a 1- to 2-week time frame. wo avenues of research have been t...

  13. The implications of Articles 37 and 40 of the Convention on the Rights of the Child for U.S. juvenile justice and U.S. ratification of the convention.

    PubMed

    Mlyniec, Wallace J

    2010-01-01

    The Convention on the Rights of the Child (CRC) guarantees that children accused of crimes will have the right to fair court procedures and humane sentences. Current U.S. laws concerning the child's age when a court has jurisdiction, and others concerning sentencing practices and the place of confinement, contravene the provisions of the CRC. Some U.S. laws are consistent with the treaty but are nonetheless not enforced. Recent developments, including increasing understanding of brain development, U.S. Supreme Court decisions on the constitutionality of punishments for children, and the Committee on the Rights of the Child General Comment 10, will have substantial impacts on U.S. ratification. This article discusses Articles 37 and 40 of the CRC and their effect on U.S. practices if the treaty is ratified.

  14. Protocols for distributive scheduling

    NASA Technical Reports Server (NTRS)

    Richards, Stephen F.; Fox, Barry

    1993-01-01

    The increasing complexity of space operations and the inclusion of interorganizational and international groups in the planning and control of space missions lead to requirements for greater communication, coordination, and cooperation among mission schedulers. These schedulers must jointly allocate scarce shared resources among the various operational and mission oriented activities while adhering to all constraints. This scheduling environment is complicated by such factors as the presence of varying perspectives and conflicting objectives among the schedulers, the need for different schedulers to work in parallel, and limited communication among schedulers. Smooth interaction among schedulers requires the use of protocols that govern such issues as resource sharing, authority to update the schedule, and communication of updates. This paper addresses the development and characteristics of such protocols and their use in a distributed scheduling environment that incorporates computer-aided scheduling tools. An example problem is drawn from the domain of space shuttle mission planning.

  15. Generalized teleportation protocol

    SciTech Connect

    Gordon, Goren; Rigolin, Gustavo

    2006-04-15

    A generalized teleportation protocol (GTP) for N qubits is presented, where the teleportation channels are nonmaximally entangled and all the free parameters of the protocol are considered: Alice's measurement basis, her sets of acceptable results, and Bob's unitary operations. The full range of fidelity (F) of the teleported state and the probability of success (P{sub suc}) to obtain a given fidelity are achieved by changing these free parameters. A channel efficiency bound is found, where one can determine how to divide it between F and P{sub suc}. A one-qubit formulation is presented and then expanded to N qubits. A proposed experimental setup that implements the GTP is given using linear optics.

  16. Experimental eavesdropping attack against Ekert's protocol based on Wigner's inequality

    SciTech Connect

    Bovino, F. A.; Colla, A. M.; Castagnoli, G.; Castelletto, S.; Degiovanni, I. P.; Rastello, M. L.

    2003-09-01

    We experimentally implemented an eavesdropping attack against the Ekert protocol for quantum key distribution based on the Wigner inequality. We demonstrate a serious lack of security of this protocol when the eavesdropper gains total control of the source. In addition we tested a modified Wigner inequality which should guarantee a secure quantum key distribution.

  17. Dysphonia risk screening protocol

    PubMed Central

    Nemr, Katia; Simões-Zenari, Marcia; da Trindade Duarte, João Marcos; Lobrigate, Karen Elena; Bagatini, Flavia Alves

    2016-01-01

    OBJECTIVE: To propose and test the applicability of a dysphonia risk screening protocol with score calculation in individuals with and without dysphonia. METHOD: This descriptive cross-sectional study included 365 individuals (41 children, 142 adult women, 91 adult men and 91 seniors) divided into a dysphonic group and a non-dysphonic group. The protocol consisted of 18 questions and a score was calculated using a 10-cm visual analog scale. The measured value on the visual analog scale was added to the overall score, along with other partial scores. Speech samples allowed for analysis/assessment of the overall degree of vocal deviation and initial definition of the respective groups and after six months, the separation of the groups was confirmed using an acoustic analysis. RESULTS: The mean total scores were different between the groups in all samples. Values ranged between 37.0 and 57.85 in the dysphonic group and between 12.95 and 19.28 in the non-dysphonic group, with overall means of 46.09 and 15.55, respectively. High sensitivity and specificity were demonstrated when discriminating between the groups with the following cut-off points: 22.50 (children), 29.25 (adult women), 22.75 (adult men), and 27.10 (seniors). CONCLUSION: The protocol demonstrated high sensitivity and specificity in differentiating groups of individuals with and without dysphonia in different sample groups and is thus an effective instrument for use in voice clinics. PMID:27074171

  18. Robust Optimization of Biological Protocols

    PubMed Central

    Flaherty, Patrick; Davis, Ronald W.

    2015-01-01

    When conducting high-throughput biological experiments, it is often necessary to develop a protocol that is both inexpensive and robust. Standard approaches are either not cost-effective or arrive at an optimized protocol that is sensitive to experimental variations. We show here a novel approach that directly minimizes the cost of the protocol while ensuring the protocol is robust to experimental variation. Our approach uses a risk-averse conditional value-at-risk criterion in a robust parameter design framework. We demonstrate this approach on a polymerase chain reaction protocol and show that our improved protocol is less expensive than the standard protocol and more robust than a protocol optimized without consideration of experimental variation. PMID:26417115

  19. A Weak Value Based QKD Protocol Robust Against Detector Attacks

    NASA Astrophysics Data System (ADS)

    Troupe, James

    2015-03-01

    We propose a variation of the BB84 quantum key distribution protocol that utilizes the properties of weak values to insure the validity of the quantum bit error rate estimates used to detect an eavesdropper. The protocol is shown theoretically to be secure against recently demonstrated attacks utilizing detector blinding and control and should also be robust against all detector based hacking. Importantly, the new protocol promises to achieve this additional security without negatively impacting the secure key generation rate as compared to that originally promised by the standard BB84 scheme. Implementation of the weak measurements needed by the protocol should be very feasible using standard quantum optical techniques.

  20. Overview of wideband packet protocols

    NASA Astrophysics Data System (ADS)

    Sherif, M. H.

    1992-10-01

    Wideband packet networks operate at rates equal to, or higher than, 64 kb/s, but lower than the basic broadband rate of 150 Mb/s, on cables or satellite links. Wideband packet protocols are the transmission protocols for these networks. They define open interfaces that can be used for public and private ISDNs. The protocols are defined in CCITT Recommendations G.764 and G.765. This paper describes the objectives of the wideband protocols, and how the objectives were achieved.

  1. From Postpartum Haemorrhage Guideline to Local Protocol: A Study of Protocol Quality.

    PubMed

    Woiski, Mallory D; van Vugt, Helena C; Dijkman, Anneke; Grol, Richard P; Marcus, Abraham; Middeldorp, Johanna M; Mol, Ben W; Mols, Femke; Oudijk, Martijn A; Porath, Martina; Scheepers, Hubertina J; Hermens, Rosella P

    2016-10-01

    Objective Postpartum hemorrhage (PPH) has a continuously rising incidence worldwide, suggesting suboptimal care. An important step in optimizing care is the translation of evidence-based guidelines into comprehensive hospital protocols. However, knowledge about the quality of these protocols is lacking. The objective of this study was to evaluate the quality of PPH-protocols on structure and content in the Netherlands. Methods We performed an observational multicenter study. Eighteen PPH-protocols from 3 University Hospitals (UH), 8 Teaching Hospitals (TH) and 7 Non-Teaching hospitals (NTH) throughout the Netherlands were acquired. The structure of the PPH-protocols was assessed using the Appraisal of Guidelines for Research and Evaluation (AGREE-II) Instrument. The content was appraised using previously developed quality indicators, based on international guidelines and Advance-Trauma-Life-Support (ATLS)-based course instructions. Results The quality of the protocols for postpartum hemorrhage for both structure and content varied widely between different hospitals, but all of them showed room for improvement. The protocols scored mainly below average on the different items of the AGREE-II instrument (8 of the 10 items scored <4 on a 1-7 scale). Regarding the content, adoption of guideline recommendations in protocols was 46 %. In addition, a timely indication of 'when to perform' a recommendation was lacking in three-fourths of the items. Conclusion This study shows that the quality of the PPH-protocols for both structure and content in the Netherlands is suboptimal. This makes adherence to the guideline and ATLS-based course instructions difficult. PMID:27395381

  2. A Survey on Underwater Acoustic Sensor Network Routing Protocols.

    PubMed

    Li, Ning; Martínez, José-Fernán; Meneses Chaus, Juan Manuel; Eckert, Martina

    2016-03-22

    Underwater acoustic sensor networks (UASNs) have become more and more important in ocean exploration applications, such as ocean monitoring, pollution detection, ocean resource management, underwater device maintenance, etc. In underwater acoustic sensor networks, since the routing protocol guarantees reliable and effective data transmission from the source node to the destination node, routing protocol design is an attractive topic for researchers. There are many routing algorithms have been proposed in recent years. To present the current state of development of UASN routing protocols, we review herein the UASN routing protocol designs reported in recent years. In this paper, all the routing protocols have been classified into different groups according to their characteristics and routing algorithms, such as the non-cross-layer design routing protocol, the traditional cross-layer design routing protocol, and the intelligent algorithm based routing protocol. This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. In addition, in this paper, we investigate the development trends of UASN routing protocols, which can provide researchers with clear and direct insights for further research.

  3. A Survey on Underwater Acoustic Sensor Network Routing Protocols

    PubMed Central

    Li, Ning; Martínez, José-Fernán; Meneses Chaus, Juan Manuel; Eckert, Martina

    2016-01-01

    Underwater acoustic sensor networks (UASNs) have become more and more important in ocean exploration applications, such as ocean monitoring, pollution detection, ocean resource management, underwater device maintenance, etc. In underwater acoustic sensor networks, since the routing protocol guarantees reliable and effective data transmission from the source node to the destination node, routing protocol design is an attractive topic for researchers. There are many routing algorithms have been proposed in recent years. To present the current state of development of UASN routing protocols, we review herein the UASN routing protocol designs reported in recent years. In this paper, all the routing protocols have been classified into different groups according to their characteristics and routing algorithms, such as the non-cross-layer design routing protocol, the traditional cross-layer design routing protocol, and the intelligent algorithm based routing protocol. This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. In addition, in this paper, we investigate the development trends of UASN routing protocols, which can provide researchers with clear and direct insights for further research. PMID:27011193

  4. A Survey on Underwater Acoustic Sensor Network Routing Protocols.

    PubMed

    Li, Ning; Martínez, José-Fernán; Meneses Chaus, Juan Manuel; Eckert, Martina

    2016-01-01

    Underwater acoustic sensor networks (UASNs) have become more and more important in ocean exploration applications, such as ocean monitoring, pollution detection, ocean resource management, underwater device maintenance, etc. In underwater acoustic sensor networks, since the routing protocol guarantees reliable and effective data transmission from the source node to the destination node, routing protocol design is an attractive topic for researchers. There are many routing algorithms have been proposed in recent years. To present the current state of development of UASN routing protocols, we review herein the UASN routing protocol designs reported in recent years. In this paper, all the routing protocols have been classified into different groups according to their characteristics and routing algorithms, such as the non-cross-layer design routing protocol, the traditional cross-layer design routing protocol, and the intelligent algorithm based routing protocol. This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. In addition, in this paper, we investigate the development trends of UASN routing protocols, which can provide researchers with clear and direct insights for further research. PMID:27011193

  5. Collaborative patient care protocols: a development process.

    PubMed

    Blaufuss, J; Wynn, J; Hujcs, M

    1993-01-01

    Computerization of these protocols is in progress. This project is funded for one year with projected completion in January 1994. This study will form a framework in which further research can be completed. Utilizing protocols will allow the measurement of nursing decision making by testing relationships between parameters and interventions and by identifying rules for decision making. For example, questions that may be answered include which physiologic parameters do clinicians treat and in what order or priority, as well as what is the impact on patient outcomes in regard to cost of care and complications. Computerized patient care protocols can be further developed to meet patient-specific needs. A computerized data base will facilitate managing large amounts of patient data and tailoring instructions to these patients. One of the goals of this project was to measure the feasibility of developing computerized patient care protocols and implementing them in a critical care setting. Eventually, this experience will facilitate implementing computerized protocols at other sites. An additional benefit is the ability to implement continuous quality improvement strategies in a prospective manner rather than by retrospective review. PMID:10171735

  6. Communication complexity protocols for qutrits

    SciTech Connect

    Tamir, Boaz

    2007-03-15

    Consider a function where its entries are distributed among many parties. Suppose each party is allowed to send only a limited amount of information to a referee. The referee can use a classical protocol to compute the value of the global function. Is there a quantum protocol improving the results of all classical protocols? In a recent work Brukner et al. showed the deep connection between such problems and the theory of Bell inequalities. Here we generalize the theory to trits. There, the best classical protocol fails whereas the quantum protocol yields the correct answer.

  7. Protocol for Communication Networking for Formation Flying

    NASA Technical Reports Server (NTRS)

    Jennings, Esther; Okino, Clayton; Gao, Jay; Clare, Loren

    2009-01-01

    An application-layer protocol and a network architecture have been proposed for data communications among multiple autonomous spacecraft that are required to fly in a precise formation in order to perform scientific observations. The protocol could also be applied to other autonomous vehicles operating in formation, including robotic aircraft, robotic land vehicles, and robotic underwater vehicles. A group of spacecraft or other vehicles to which the protocol applies could be characterized as a precision-formation- flying (PFF) network, and each vehicle could be characterized as a node in the PFF network. In order to support precise formation flying, it would be necessary to establish a corresponding communication network, through which the vehicles could exchange position and orientation data and formation-control commands. The communication network must enable communication during early phases of a mission, when little positional knowledge is available. Particularly during early mission phases, the distances among vehicles may be so large that communication could be achieved only by relaying across multiple links. The large distances and need for omnidirectional coverage would limit communication links to operation at low bandwidth during these mission phases. Once the vehicles were in formation and distances were shorter, the communication network would be required to provide high-bandwidth, low-jitter service to support tight formation-control loops. The proposed protocol and architecture, intended to satisfy the aforementioned and other requirements, are based on a standard layered-reference-model concept. The proposed application protocol would be used in conjunction with conventional network, data-link, and physical-layer protocols. The proposed protocol includes the ubiquitous Institute of Electrical and Electronics Engineers (IEEE) 802.11 medium access control (MAC) protocol to be used in the datalink layer. In addition to its widespread and proven use in

  8. PROFILE: Environmental Impact Assessment Under the National Environmental Policy Act and the Protocol on Environmental Protection to the Antarctic Treaty.

    PubMed

    Ensminger; McCold; Webb

    1999-07-01

    / Antarctica has been set aside by the international community for protection as a natural reserve and a place for scientific research. Through the Antarctic Treaty of 1961, the signing nations agreed to cooperate in protecting the antarctic environment, in conducting scientific studies, and in abstaining from the exercise of territorial claims. The 1991 signing of the Protocol on Environmental Protection to the Antarctic Treaty (Protocol) by representatives of the 26 nations comprising the Antarctic Treaty Consultative Parties (Parties) significantly strengthened environmental protection measures for the continent. The Protocol required ratification by each of the governments individually prior to official implementation. The US government ratified the Protocol by passage of the Antarctic Science, Tourism, and Conservation Act of 1997. Japan completed the process by ratifying the Protocol on December 15, 1997. US government actions undertaken in Antarctica are subject to the requirements of both the Protocol and the US National Environmental Policy Act (NEPA). There are differences in the scope and intent of the Protocol and NEPA; however, both require environmental impact assessment (EIA) as part of the planning process for proposed actions that have the potential for environmental impacts. In this paper we describe the two instruments and highlight key similarities and differences with particular attention to EIA. Through this comparison of the EIA requirements of NEPA and the Protocol, we show how the requirements of each can be used in concert to provide enhanced environmental protection for the antarctic environment. NEPA applies only to actions of the US government; therefore, because NEPA includes certain desirable attributes that have been refined and clarified through numerous court cases, and because the Protocol is just entering implementation internationally, some recommendations are made for strengthening the procedural requirements of the Protocol

  9. Optical Circuit Switched Protocol

    NASA Technical Reports Server (NTRS)

    Monacos, Steve P. (Inventor)

    2000-01-01

    The present invention is a system and method embodied in an optical circuit switched protocol for the transmission of data through a network. The optical circuit switched protocol is an all-optical circuit switched network and includes novel optical switching nodes for transmitting optical data packets within a network. Each optical switching node comprises a detector for receiving the header, header detection logic for translating the header into routing information and eliminating the header, and a controller for receiving the routing information and configuring an all optical path within the node. The all optical path located within the node is solely an optical path without having electronic storage of the data and without having optical delay of the data. Since electronic storage of the header is not necessary and the initial header is eliminated by the first detector of the first switching node. multiple identical headers are sent throughout the network so that subsequent switching nodes can receive and read the header for setting up an optical data path.

  10. Protocol Architecture Model Report

    NASA Technical Reports Server (NTRS)

    Dhas, Chris

    2000-01-01

    NASA's Glenn Research Center (GRC) defines and develops advanced technology for high priority national needs in communications technologies for application to aeronautics and space. GRC tasked Computer Networks and Software Inc. (CNS) to examine protocols and architectures for an In-Space Internet Node. CNS has developed a methodology for network reference models to support NASA's four mission areas: Earth Science, Space Science, Human Exploration and Development of Space (REDS), Aerospace Technology. This report applies the methodology to three space Internet-based communications scenarios for future missions. CNS has conceptualized, designed, and developed space Internet-based communications protocols and architectures for each of the independent scenarios. The scenarios are: Scenario 1: Unicast communications between a Low-Earth-Orbit (LEO) spacecraft inspace Internet node and a ground terminal Internet node via a Tracking and Data Rela Satellite (TDRS) transfer; Scenario 2: Unicast communications between a Low-Earth-Orbit (LEO) International Space Station and a ground terminal Internet node via a TDRS transfer; Scenario 3: Multicast Communications (or "Multicasting"), 1 Spacecraft to N Ground Receivers, N Ground Transmitters to 1 Ground Receiver via a Spacecraft.

  11. Protocol for a Delay-Tolerant Data-Communication Network

    NASA Technical Reports Server (NTRS)

    Torgerson, Jordan; Hooke, Adrian; Burleigh, Scott; Fall, Kevin

    2004-01-01

    As its name partly indicates, the Delay-Tolerant Networking (DTN) Bundle Protocol is a protocol for delay-tolerant transmission of data via communication networks. This protocol was conceived as a result of studies of how to adapt Internet protocols so that Internet-like services could be provided across interplanetary distances in support of deep-space exploration. The protocol, and software to implement the protocol, is being developed in collaboration among experts at NASA's Jet Propulsion Laboratory and other institutions. No current Internet protocols can accommodate long transmission delay times or intermittent link connectivity. The DTN Bundle Protocol represents a departure from the standard Internet assumption that a continuous path is available from a host computer to a client computer: It provides for routing of data through networks that may be disjointed and may be characterized by long transmission delays. In addition to networks that include deepspace communication links, examples of such networks include terrestrial ones within which branches are temporarily disconnected. The protocol is based partly on the definition of a message-based overlay above the transport layers of the networks on which it is hosted.

  12. Canine adenovirus downstream processing protocol.

    PubMed

    Puig, Meritxell; Piedra, Jose; Miravet, Susana; Segura, María Mercedes

    2014-01-01

    Adenovirus vectors are efficient gene delivery tools. A major caveat with vectors derived from common human adenovirus serotypes is that most adults are likely to have been exposed to the wild-type virus and exhibit active immunity against the vectors. This preexisting immunity limits their clinical success. Strategies to circumvent this problem include the use of nonhuman adenovirus vectors. Vectors derived from canine adenovirus type 2 (CAV-2) are among the best-studied representatives. CAV-2 vectors are particularly attractive for the treatment of neurodegenerative disorders. In addition, CAV-2 vectors have shown great promise as oncolytic agents in virotherapy approaches and as vectors for recombinant vaccines. The rising interest in CAV-2 vectors calls for the development of scalable GMP compliant production and purification strategies. A detailed protocol describing a complete scalable downstream processing strategy for CAV-2 vectors is reported here. Clarification of CAV-2 particles is achieved by microfiltration. CAV-2 particles are subsequently concentrated and partially purified by ultrafiltration-diafiltration. A Benzonase(®) digestion step is carried out between ultrafiltration and diafiltration operations to eliminate contaminating nucleic acids. Chromatography purification is accomplished in two consecutive steps. CAV-2 particles are first captured and concentrated on a propyl hydrophobic interaction chromatography column followed by a polishing step using DEAE anion exchange monoliths. Using this protocol, high-quality CAV-2 vector preparations containing low levels of contamination with empty viral capsids and other inactive vector forms are typically obtained. The complete process yield was estimated to be 38-45 %. PMID:24132487

  13. Clinical Protocol Information System

    PubMed Central

    Wirtschafter, David D.; Gams, Richard; Ferguson, Carol; Blackwell, William; Boackle, Paul

    1980-01-01

    The Clinical Protocol Information System (CPIS) supports the clinical research and patient care objectives of the SouthEastern Cancer Study Group (SEG). The information system goals are to improve the evaluability of clinical trials, decrease the frequency of adverse patient events, implement drug toxicity surveillance, improve the availability of study data and demonstrate the criteria for computer networks that can impact on the general medical care of the community. Nodes in the network consist of Data General MicroNova MP-100 minicomputers that drive the interactive data dialogue and communicate with the network concentrator (another DG MicroNova) in Birmingham. Functions supported include: source data editing, care “advice,” care “audit,” care “explanation,” and treatment note printing. The complete database is updated nightly and resides on UAB's IBM 370/158-AP.

  14. A Hybrid Quorum Protocol for Improved Availability, Capacity, Load and Reduced Overhead

    NASA Astrophysics Data System (ADS)

    Pandey, Parul; Tripathi, Maheshwari

    2016-06-01

    Data replication is playing a vital role in the design of distributed information systems. This paper presents a novel and efficient distributed algorithm for managing replicated data and for better performance and availability. This paper presents an extension to existing wheel protocol for improved performance. Wheel protocol imposes a logical wheel structure on the set of copies of an object and gives smallest read quorum. In addition to small read quorum size for read intensive applications, it is necessary to have good write availability as well. This paper proposes two hybrid wheel protocols, which superimpose logarithmic and ring protocols on top of the wheel protocol. It shows that, both protocols help in improving write availability, read capacity, load and message overhead and also compare their performances with wheel and other protocols. Hybrid protocols expand usage of wheel protocol to different type of applications.

  15. A Hybrid Quorum Protocol for Improved Availability, Capacity, Load and Reduced Overhead

    NASA Astrophysics Data System (ADS)

    Pandey, Parul; Tripathi, Maheshwari

    2016-12-01

    Data replication is playing a vital role in the design of distributed information systems. This paper presents a novel and efficient distributed algorithm for managing replicated data and for better performance and availability. This paper presents an extension to existing wheel protocol for improved performance. Wheel protocol imposes a logical wheel structure on the set of copies of an object and gives smallest read quorum. In addition to small read quorum size for read intensive applications, it is necessary to have good write availability as well. This paper proposes two hybrid wheel protocols, which superimpose logarithmic and ring protocols on top of the wheel protocol. It shows that, both protocols help in improving write availability, read capacity, load and message overhead and also compare their performances with wheel and other protocols. Hybrid protocols expand usage of wheel protocol to different type of applications.

  16. A Bayesian approach to optimizing cryopreservation protocols.

    PubMed

    Sambu, Sammy

    2015-01-01

    Cryopreservation is beset with the challenge of protocol alignment across a wide range of cell types and process variables. By taking a cross-sectional assessment of previously published cryopreservation data (sample means and standard errors) as preliminary meta-data, a decision tree learning analysis (DTLA) was performed to develop an understanding of target survival using optimized pruning methods based on different approaches. Briefly, a clear direction on the decision process for selection of methods was developed with key choices being the cooling rate, plunge temperature on the one hand and biomaterial choice, use of composites (sugars and proteins as additional constituents), loading procedure and cell location in 3D scaffolding on the other. Secondly, using machine learning and generalized approaches via the Naïve Bayes Classification (NBC) method, these metadata were used to develop posterior probabilities for combinatorial approaches that were implicitly recorded in the metadata. These latter results showed that newer protocol choices developed using probability elicitation techniques can unearth improved protocols consistent with multiple unidimensionally-optimized physical protocols. In conclusion, this article proposes the use of DTLA models and subsequently NBC for the improvement of modern cryopreservation techniques through an integrative approach.

  17. APFBC repowering could help meet Kyoto Protocol CO{sub 2} reduction goals[Advanced Pressurized Fluidized Bed Combustion

    SciTech Connect

    Weinstein, R.E.; Tonnemacher, G.C.

    1999-07-01

    The Clinton Administration signed the 1997 Kyoto Protocol agreement that would limit US greenhouse gas emissions, of which carbon dioxide (CO{sub 2}) is the most significant. While the Kyoto Protocol has not yet been submitted to the Senate for ratification, in the past, there have been few proposed environmental actions that had continued and wide-spread attention of the press and environmental activists that did not eventually lead to regulation. Since the Kyoto Protocol might lead to future regulation, its implications need investigation by the power industry. Limiting CO{sub 2} emissions affects the ability of the US to generate reliable, low cost electricity, and has tremendous potential impact on electric generating companies with a significant investment in coal-fired generation, and on their customers. This paper explores the implications of reducing coal plant CO{sub 2} by various amounts. The amount of reduction for the US that is proposed in the Kyoto Protocol is huge. The Kyoto Protocol would commit the US to reduce its CO{sub 2} emissions to 7% below 1990 levels. Since 1990, there has been significant growth in US population and the US economy driving carbon emissions 34% higher by year 2010. That means CO{sub 2} would have to be reduced by 30.9%, which is extremely difficult to accomplish. The paper tells why. There are, however, coal-based technologies that should be available in time to make significant reductions in coal-plant CO{sub 2} emissions. Th paper focuses on one plant repowering method that can reduce CO{sub 2} per kWh by 25%, advanced circulating pressurized fluidized bed combustion combined cycle (APFBC) technology, based on results from a recent APFBC repowering concept evaluation of the Carolina Power and Light Company's (CP and L) L.V. Sutton steam station. The replacement of the existing 50-year base of power generating units needed to meet proposed Kyoto Protocol CO{sub 2} reduction commitments would be a massive undertaking. It is

  18. The importance of the Montreal Protocol in protecting climate

    PubMed Central

    Velders, Guus J. M.; Andersen, Stephen O.; Daniel, John S.; Fahey, David W.; McFarland, Mack

    2007-01-01

    The 1987 Montreal Protocol on Substances that Deplete the Ozone Layer is a landmark agreement that has successfully reduced the global production, consumption, and emissions of ozone-depleting substances (ODSs). ODSs are also greenhouse gases that contribute to the radiative forcing of climate change. Using historical ODSs emissions and scenarios of potential emissions, we show that the ODS contribution to radiative forcing most likely would have been much larger if the ODS link to stratospheric ozone depletion had not been recognized in 1974 and followed by a series of regulations. The climate protection already achieved by the Montreal Protocol alone is far larger than the reduction target of the first commitment period of the Kyoto Protocol. Additional climate benefits that are significant compared with the Kyoto Protocol reduction target could be achieved by actions under the Montreal Protocol, by managing the emissions of substitute fluorocarbon gases and/or implementing alternative gases with lower global warming potentials. PMID:17360370

  19. The importance of the Montreal Protocol in protecting climate.

    PubMed

    Velders, Guus J M; Andersen, Stephen O; Daniel, John S; Fahey, David W; McFarland, Mack

    2007-03-20

    The 1987 Montreal Protocol on Substances that Deplete the Ozone Layer is a landmark agreement that has successfully reduced the global production, consumption, and emissions of ozone-depleting substances (ODSs). ODSs are also greenhouse gases that contribute to the radiative forcing of climate change. Using historical ODSs emissions and scenarios of potential emissions, we show that the ODS contribution to radiative forcing most likely would have been much larger if the ODS link to stratospheric ozone depletion had not been recognized in 1974 and followed by a series of regulations. The climate protection already achieved by the Montreal Protocol alone is far larger than the reduction target of the first commitment period of the Kyoto Protocol. Additional climate benefits that are significant compared with the Kyoto Protocol reduction target could be achieved by actions under the Montreal Protocol, by managing the emissions of substitute fluorocarbon gases and/or implementing alternative gases with lower global warming potentials.

  20. Experimental Demonstration of a Quantum Protocol for Byzantine Agreement and Liar Detection

    NASA Astrophysics Data System (ADS)

    Gaertner, Sascha; Bourennane, Mohamed; Kurtsiefer, Christian; Cabello, Adán; Weinfurter, Harald

    2008-02-01

    We introduce a new quantum protocol for solving detectable Byzantine agreement (also called detectable broadcast) between three parties, and also for solving the detectable liar detection problem. The protocol is suggested by the properties of a four-qubit entangled state, and the classical part of the protocol is simpler than that of previous proposals. In addition, we present an experimental implementation of the protocol using four-photon entanglement.

  1. Experimental demonstration of a quantum protocol for byzantine agreement and liar detection.

    PubMed

    Gaertner, Sascha; Bourennane, Mohamed; Kurtsiefer, Christian; Cabello, Adán; Weinfurter, Harald

    2008-02-22

    We introduce a new quantum protocol for solving detectable Byzantine agreement (also called detectable broadcast) between three parties, and also for solving the detectable liar detection problem. The protocol is suggested by the properties of a four-qubit entangled state, and the classical part of the protocol is simpler than that of previous proposals. In addition, we present an experimental implementation of the protocol using four-photon entanglement.

  2. PROTOCOL FOR EXAMINATION OF THE INNER CAN CLOSURE WELD REGION FOR 3013 DE CONTAINERS

    SciTech Connect

    Mickalonis, J.

    2014-09-16

    The protocol for the examination of the inner can closure weld region (ICCWR) for 3013 DE containers is presented within this report. The protocol includes sectioning of the inner can lid section, documenting the surface condition, measuring corrosion parameters, and storing of samples. This protocol may change as the investigation develops since findings may necessitate additional steps be taken. Details of the previous analyses, which formed the basis for this protocol, are also presented.

  3. Publishing protocols for partnered research.

    PubMed

    Hysong, Sylvia J; Woodard, LeChauncy; Garvin, Jennifer H; Murawsky, Jeffrey; Petersen, Laura A

    2014-12-01

    Published scientific protocols are advocated as a means of controlling bias in research reporting. Indeed, many journals require a study protocol with manuscript submission. However, publishing protocols of partnered research (PPR) can be challenging in light of the research model's dynamic nature, especially as no current reporting standards exist. Nevertheless, as these protocols become more prevalent, a priori documentation of methods in partnered research studies becomes increasingly important. Using as illustration a suite of studies aimed at improving coordination and communication in the primary care setting, we sought to identify challenges in publishing PPR relative to traditional designs, present alternative solutions to PPR publication, and propose an initial checklist of content to be included in protocols of partnered research. Challenges to publishing PPR include reporting details of research components intended to be co-created with operational partners, changes to sampling and entry strategy, and alignment of scientific and operational goals. Proposed solutions include emulating reporting standards of qualitative research, participatory action research, and adaptive trial designs, as well as embracing technological tools that facilitate publishing adaptive protocols, with version histories that are able to be updated as major protocol changes occur. Finally, we present a proposed checklist of reporting elements for partnered research protocols. PMID:25355092

  4. The simulation of communication protocols

    NASA Astrophysics Data System (ADS)

    de Carvalho Viola, F. E.

    1985-12-01

    Simulators for communication protocols specified in the ESTELLE and LC/1 languages are developed. The general principles of protocol simulation are reviewed; ESTELLE and LC/1 are characterized; a prototype LC/1 simulator based on predicate Petri nets is described; and a detailed specification for a driving interface for an ESTELLE simulator is given.

  5. Publishing protocols for partnered research.

    PubMed

    Hysong, Sylvia J; Woodard, LeChauncy; Garvin, Jennifer H; Murawsky, Jeffrey; Petersen, Laura A

    2014-12-01

    Published scientific protocols are advocated as a means of controlling bias in research reporting. Indeed, many journals require a study protocol with manuscript submission. However, publishing protocols of partnered research (PPR) can be challenging in light of the research model's dynamic nature, especially as no current reporting standards exist. Nevertheless, as these protocols become more prevalent, a priori documentation of methods in partnered research studies becomes increasingly important. Using as illustration a suite of studies aimed at improving coordination and communication in the primary care setting, we sought to identify challenges in publishing PPR relative to traditional designs, present alternative solutions to PPR publication, and propose an initial checklist of content to be included in protocols of partnered research. Challenges to publishing PPR include reporting details of research components intended to be co-created with operational partners, changes to sampling and entry strategy, and alignment of scientific and operational goals. Proposed solutions include emulating reporting standards of qualitative research, participatory action research, and adaptive trial designs, as well as embracing technological tools that facilitate publishing adaptive protocols, with version histories that are able to be updated as major protocol changes occur. Finally, we present a proposed checklist of reporting elements for partnered research protocols.

  6. Protocol for determining bull trout presence

    USGS Publications Warehouse

    Peterson, James; Dunham, Jason B.; Howell, Philip; Thurow, Russell; Bonar, Scott

    2002-01-01

    The Western Division of the American Fisheries Society was requested to develop protocols for determining presence/absence and potential habitat suitability for bull trout. The general approach adopted is similar to the process for the marbled murrelet, whereby interim guidelines are initially used, and the protocols are subsequently refined as data are collected. Current data were considered inadequate to precisely identify suitable habitat but could be useful in stratifying sampling units for presence/absence surveys. The presence/absence protocol builds on previous approaches (Hillman and Platts 1993; Bonar et al. 1997), except it uses the variation in observed bull trout densities instead of a minimum threshold density and adjusts for measured differences in sampling efficiency due to gear types and habitat characteristics. The protocol consists of: 1. recommended sample sizes with 80% and 95% detection probabilities for juvenile and resident adult bull trout for day and night snorkeling and electrofishing adjusted for varying habitat characteristics for 50m and 100m sampling units, 2. sampling design considerations, including possible habitat characteristics for stratification, 3. habitat variables to be measured in the sampling units, and 3. guidelines for training sampling crews. Criteria for habitat strata consist of coarse, watershed-scale characteristics (e.g., mean annual air temperature) and fine-scale, reach and habitat-specific features (e.g., water temperature, channel width). The protocols will be revised in the future using data from ongoing presence/absence surveys, additional research on sampling efficiencies, and development of models of habitat/species occurrence.

  7. Apples to apples: the origin and magnitude of differences in asbestos cancer risk estimates derived using varying protocols.

    PubMed

    Berman, D Wayne

    2011-08-01

    Given that new protocols for assessing asbestos-related cancer risk have recently been published, questions arise concerning how they compare to the "IRIS" protocol currently used by regulators. The newest protocols incorporate findings from 20 additional years of literature. Thus, differences between the IRIS and newer Berman and Crump protocols are examined to evaluate whether these protocols can be reconciled. Risks estimated by applying these protocols to real exposure data from both laboratory and field studies are also compared to assess the relative health protectiveness of each protocol. The reliability of risks estimated using the two protocols are compared by evaluating the degree with which each potentially reproduces the known epidemiology study risks. Results indicate that the IRIS and Berman and Crump protocols can be reconciled; while environment-specific variation within fiber type is apparently due primarily to size effects (not addressed by IRIS), the 10-fold (average) difference between amphibole asbestos risks estimated using each protocol is attributable to an arbitrary selection of the lowest of available mesothelioma potency factors in the IRIS protocol. Thus, the IRIS protocol may substantially underestimate risk when exposure is primarily to amphibole asbestos. Moreover, while the Berman and Crump protocol is more reliable than the IRIS protocol overall (especially for predicting amphibole risk), evidence is presented suggesting a new fiber-size-related adjustment to the Berman and Crump protocol may ultimately succeed in reconciling the entire epidemiology database. However, additional data need to be developed before the performance of the adjusted protocol can be fully validated.

  8. A Secure Authenticated Key Exchange Protocol for Credential Services

    NASA Astrophysics Data System (ADS)

    Shin, Seonghan; Kobara, Kazukuni; Imai, Hideki

    In this paper, we propose a leakage-resilient and proactive authenticated key exchange (called LRP-AKE) protocol for credential services which provides not only a higher level of security against leakage of stored secrets but also secrecy of private key with respect to the involving server. And we show that the LRP-AKE protocol is provably secure in the random oracle model with the reduction to the computational Difie-Hellman problem. In addition, we discuss about some possible applications of the LRP-AKE protocol.

  9. Protocols.io: Virtual Communities for Protocol Development and Discussion.

    PubMed

    Teytelman, Leonid; Stoliartchouk, Alexei; Kindler, Lori; Hurwitz, Bonnie L

    2016-08-01

    The detailed know-how to implement research protocols frequently remains restricted to the research group that developed the method or technology. This knowledge often exists at a level that is too detailed for inclusion in the methods section of scientific articles. Consequently, methods are not easily reproduced, leading to a loss of time and effort by other researchers. The challenge is to develop a method-centered collaborative platform to connect with fellow researchers and discover state-of-the-art knowledge. Protocols.io is an open-access platform for detailing, sharing, and discussing molecular and computational protocols that can be useful before, during, and after publication of research results.

  10. Internet-Protocol-Based Satellite Bus Architecture Designed

    NASA Technical Reports Server (NTRS)

    Slywczak, Richard A.

    2004-01-01

    NASA is designing future complex satellite missions ranging from single satellites and constellations to space networks and sensor webs. These missions require more interoperability, autonomy, and coordination than previous missions; in addition, a desire exists to have scientists retrieve data directly from the satellite rather than a central distribution source. To meet these goals, NASA has been studying the possibility of extending the Transmission Control Protocol/Internet Protocol (TCP/IP) suite for spacebased applications.

  11. A Self-Stabilizing Synchronization Protocol for Arbitrary Digraphs

    NASA Technical Reports Server (NTRS)

    Malekpour, Mahyar R.

    2011-01-01

    This paper presents a self-stabilizing distributed clock synchronization protocol in the absence of faults in the system. It is focused on the distributed clock synchronization of an arbitrary, non-partitioned digraph ranging from fully connected to 1-connected networks of nodes while allowing for differences in the network elements. This protocol does not rely on assumptions about the initial state of the system, other than the presence of at least one node, and no central clock or a centrally generated signal, pulse, or message is used. Nodes are anonymous, i.e., they do not have unique identities. There is no theoretical limit on the maximum number of participating nodes. The only constraint on the behavior of the node is that the interactions with other nodes are restricted to defined links and interfaces. This protocol deterministically converges within a time bound that is a linear function of the self-stabilization period. We present an outline of a deductive proof of the correctness of the protocol. A bounded model of the protocol was mechanically verified for a variety of topologies. Results of the mechanical proof of the correctness of the protocol are provided. The model checking results have verified the correctness of the protocol as they apply to the networks with unidirectional and bidirectional links. In addition, the results confirm the claims of determinism and linear convergence. As a result, we conjecture that the protocol solves the general case of this problem. We also present several variations of the protocol and discuss that this synchronization protocol is indeed an emergent system.

  12. EPA Protocol Gas Verification Program

    EPA Science Inventory

    Accurate compressed gas calibration standards are needed to calibrate continuous emission monitors (CEMs) and ambient air quality monitors that are being used for regulatory purposes. US Environmental Protection Agency (EPA) established its traceability protocol to ensure that co...

  13. QUALITY CONTROL - VARIABILITY IN PROTOCOLS

    EPA Science Inventory

    The EPA Risk Reduction Engineering Laboratory’s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

  14. On the Cost of Prioritized Atomic Multicast Protocols

    NASA Astrophysics Data System (ADS)

    Miedes, Emili; Muñoz-Escoí, Francesc D.

    A prioritized atomic multicast protocol allows an application to tag messages with a priority that expresses their urgency and tries to deliver first those with a higher priority. For instance, such a service can be used in a database replication context, to reduce the transaction abort rate when integrity constraints are used. We present a study of the three most important and well-known classes of atomic multicast protocols in which we evaluate the cost imposed by the prioritization mechanisms, in terms of additional latency overhead, computational cost and memory use. This study reveals that the behavior of the protocols depends on the particular properties of the setting (number of nodes, message sending rates, etc.) and that the extra work done by a prioritized protocol does not introduce any additional latency overhead in most of the evaluated settings. This study is also a performance comparison of these classes of total order protocols and can be used by system designers to choose the proper prioritized protocol for a given deployment.

  15. A Voting Protocol Based on the Controlled Quantum Operation Teleportation

    NASA Astrophysics Data System (ADS)

    Tian, Juan-Hong; Zhang, Jian-Zhong; Li, Yan-Ping

    2016-05-01

    Based on the controlled quantum operation teleportation, a secure voting protocol is proposed in this paper. Genuine four-qubit entangled state functions as the quantum channel. The eligible voter's quantum operation which represents his vote information can be transmitted to the tallyman Bob with the help of the scrutineer Charlie. Voter's quantum identity authentication provides the anonymity of voters'ID, which is ensured by a zero-knowledge proof of the notary organization CA. Charlie's supervision in the whole voting process can make the protocol satisfy verifiability and non-reusability so as to avoid Bob's dishonest behaviour. The security analysis shows that the voting protocol satisfies unforgeability, and has great advantages over some relevant researches. Additionally, the quantum operation can be transmitted successfully with the probability 1, which can make the protocol reliable and practical.

  16. Early action to reduce greenhouse gas emissions before the commitment period of the Kyoto protocol: advantages and disadvantages.

    PubMed

    Michaelowa, A; Rolfe, C

    2001-09-01

    Current "business as usual" projections suggest greenhouse gas emissions from industrialized nations will grow substantially over the next decade. However, if it comes into force, the Kyoto Protocol will require industrialized nations to reduce emissions to an average of 5% below 1990 levels in the 2008-2012 period. Taking early action to close this gap has a number of advantages. It reduces the risks of passing thresholds that trigger climate change "surprises." Early action also increases future generations' ability to choose greater levels of climate protection, and it leads to faster reductions of other pollutants. From an economic sense, early action is important because it allows shifts to less carbon-intensive technologies during the course of normal capital stock turnover. Moreover, many options for emission reduction have negative costs, and thus are economically worthwhile, because of paybacks in energy costs, healthcare costs, and other benefits. Finally, early emission reductions enhance the probability of successful ratification and lower the risk of noncompliance with the protocol. We discuss policy approaches for the period prior to 2008. Disadvantages of the current proposals for Credit for Early Action are the possibility of adverse selection due to problematic baseline calculation methods as well as the distributionary impacts of allocating a part of the emissions budget already before 2008. One simple policy without drawbacks is the so-called baseline protection, which removes the disincentive to early action due to the expectation that businesses may, in the future, receive emission rights in proportion to past emissions. It is particularly important to adopt policies that shift investment in long-lived capital stock towards less carbon-intensive technologies and to encourage innovation and technology development that will reduce future compliance costs.

  17. Protocols.io: Virtual Communities for Protocol Development and Discussion

    PubMed Central

    Stoliartchouk, Alexei; Kindler, Lori; Hurwitz, Bonnie L.

    2016-01-01

    The detailed know-how to implement research protocols frequently remains restricted to the research group that developed the method or technology. This knowledge often exists at a level that is too detailed for inclusion in the methods section of scientific articles. Consequently, methods are not easily reproduced, leading to a loss of time and effort by other researchers. The challenge is to develop a method-centered collaborative platform to connect with fellow researchers and discover state-of-the-art knowledge. Protocols.io is an open-access platform for detailing, sharing, and discussing molecular and computational protocols that can be useful before, during, and after publication of research results. PMID:27547938

  18. Protocols.io: Virtual Communities for Protocol Development and Discussion.

    PubMed

    Teytelman, Leonid; Stoliartchouk, Alexei; Kindler, Lori; Hurwitz, Bonnie L

    2016-08-01

    The detailed know-how to implement research protocols frequently remains restricted to the research group that developed the method or technology. This knowledge often exists at a level that is too detailed for inclusion in the methods section of scientific articles. Consequently, methods are not easily reproduced, leading to a loss of time and effort by other researchers. The challenge is to develop a method-centered collaborative platform to connect with fellow researchers and discover state-of-the-art knowledge. Protocols.io is an open-access platform for detailing, sharing, and discussing molecular and computational protocols that can be useful before, during, and after publication of research results. PMID:27547938

  19. Lightweight Distance Bounding Protocol against Relay Attacks

    NASA Astrophysics Data System (ADS)

    Kim, Jin Seok; Cho, Kookrae; Yum, Dae Hyun; Hong, Sung Je; Lee, Pil Joong

    Traditional authentication protocols are based on cryptographic techniques to achieve identity verification. Distance bounding protocols are an enhanced type of authentication protocol built upon both signal traversal time measurement and cryptographic techniques to accomplish distance verification as well as identity verification. A distance bounding protocol is usually designed to defend against the relay attack and the distance fraud attack. As there are applications to which the distance fraud attack is not a serious threat, we propose a streamlined distance bounding protocol that focuses on the relay attack. The proposed protocol is more efficient than previous protocols and has a low false acceptance rate under the relay attack.

  20. Protocol for Uniformly Measuring and Expressing the Performance of Energy Storage Systems

    SciTech Connect

    Conover, David R.; Crawford, Aladsair J.; Viswanathan, Vilayanur V.; Ferreira, Summer; Schoenwald, David

    2014-06-01

    The Protocol for Uniformly Measuring and Expressing the Performance of Energy Storage Systems (PNNL-22010) was first issued in November 2012 as a first step toward providing a foundational basis for developing an initial standard for the uniform measurement and expression of energy storage system (ESS) performance. Its subsequent use in the field and review by the protocol working group and most importantly the users’ subgroup and the thermal subgroup has led to the fundamental modifications reflected in this update of the 2012 Protocol. As an update of the 2012 Protocol, this document (the June 2014 Protocol) is intended to supersede its predecessor and be used as the basis for measuring and expressing ESS performance. The foreword provides general and specific details about what additions, revisions, and enhancements have been made to the 2012 Protocol and the rationale for them in arriving at the June 2014 Protocol.

  1. A Simple XML Producer-Consumer Protocol

    NASA Technical Reports Server (NTRS)

    Smith, Warren; Gunter, Dan; Quesnel, Darcy

    2000-01-01

    This document describes a simple XML-based protocol that can be used for producers of events to communicate with consumers of events. The protocol described here is not meant to be the most efficient protocol, the most logical protocol, or the best protocol in any way. This protocol was defined quickly and it's intent is to give us a reasonable protocol that we can implement relatively easily and then use to gain experience in distributed event services. This experience will help us evaluate proposals for event representations, XML-based encoding of information, and communication protocols. The next section of this document describes how we represent events in this protocol and then defines the two events that we choose to use for our initial experiments. These definitions are made by example so that they are informal and easy to understand. The following section then proceeds to define the producer-consumer protocol we have agreed upon for our initial experiments.

  2. Developing protocols for obstetric emergencies.

    PubMed

    Roth, Cheryl K; Parfitt, Sheryl E; Hering, Sandra L; Dent, Sarah A

    2014-01-01

    There is potential for important steps to be missed in emergency situations, even in the presence of many health care team members. Developing a clear plan of response for common emergencies can ensure that no tasks are redundant or omitted, and can create a more controlled environment that promotes positive health outcomes. A multidisciplinary team was assembled in a large community hospital to create protocols that would help ensure optimum care and continuity of practice in cases of postpartum hemorrhage, shoulder dystocia, emergency cesarean surgical birth, eclamptic seizure and maternal code. Assignment of team roles and responsibilities led to the evolution of standardized protocols for each emergency situation.

  3. FTP Extensions for Variable Protocol Specification

    NASA Technical Reports Server (NTRS)

    Allman, Mark; Ostermann, Shawn

    2000-01-01

    The specification for the File Transfer Protocol (FTP) assumes that the underlying network protocols use a 32-bit network address and a 16-bit transport address (specifically IP version 4 and TCP). With the deployment of version 6 of the Internet Protocol, network addresses will no longer be 32-bits. This paper species extensions to FTP that will allow the protocol to work over a variety of network and transport protocols.

  4. Internet Protocol Enhanced over Satellite Networks

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    1999-01-01

    Extensive research conducted by the Satellite Networks and Architectures Branch of the NASA Lewis Research Center led to an experimental change to the Internet's Transmission Control Protocol (TCP) that will increase performance over satellite channels. The change raises the size of the initial burst of data TCP can send from 1 packet to 4 packets or roughly 4 kilobytes (kB), whichever is less. TCP is used daily by everyone on the Internet for e-mail and World Wide Web access, as well as other services. TCP is one of the feature protocols used in computer communications for reliable data delivery and file transfer. Increasing TCP's initial data burst from the previously specified single segment to approximately 4 kB may improve data transfer rates by up to 27 percent for very small files. This is significant because most file transfers in wide-area networks today are small files, 4 kilobytes or less. In addition, because data transfers over geostationary satellites can take 5 to 20 times longer than over typical terrestrial connections, increasing the initial burst of data that can be sent is extremely important. This research along with research from other institutions has led to the release of two new Request for Comments from the Internet Engineering Task Force (IETF, the international body that sets Internet standards). In addition, two studies of the implications of this mechanism were also funded by NASA Lewis.

  5. Design and Verification of a Distributed Communication Protocol

    NASA Technical Reports Server (NTRS)

    Munoz, Cesar A.; Goodloe, Alwyn E.

    2009-01-01

    The safety of remotely operated vehicles depends on the correctness of the distributed protocol that facilitates the communication between the vehicle and the operator. A failure in this communication can result in catastrophic loss of the vehicle. To complicate matters, the communication system may be required to satisfy several, possibly conflicting, requirements. The design of protocols is typically an informal process based on successive iterations of a prototype implementation. Yet distributed protocols are notoriously difficult to get correct using such informal techniques. We present a formal specification of the design of a distributed protocol intended for use in a remotely operated vehicle, which is built from the composition of several simpler protocols. We demonstrate proof strategies that allow us to prove properties of each component protocol individually while ensuring that the property is preserved in the composition forming the entire system. Given that designs are likely to evolve as additional requirements emerge, we show how we have automated most of the repetitive proof steps to enable verification of rapidly changing designs.

  6. Extensible Authentication Protocol Overview and Its Applications

    NASA Astrophysics Data System (ADS)

    Youm, Heung Youl

    The Extensible Authentication Protocol (EAP) is an authentication framework that supports multiple authentication mechanisms [38] between a peer and an authentication server in a data communication network. EAP is used as a useful tool for enabling user authentication and distribution of session keys. There are numerous EAP methods that have been developed by global SDOs such as IETF, IEEE, ITU-T, and 3GPP. In this paper, we analyze the most widely deployed EAP methods ranging from the EAP-TLS [27] to the EAP-PSK [25]. In addition, we derive the security requirements of EAP methods meet, evaluate the typical EAP methods in terms of the security requirements, and discuss the features of the existing widely-deployed EAP methods. In addition, we identify two typical use cases for the EAP methods. Finally, recent global standardization activities in this area are reviewed.

  7. Biocoder: A programming language for standardizing and automating biology protocols

    PubMed Central

    2010-01-01

    Background Published descriptions of biology protocols are often ambiguous and incomplete, making them difficult to replicate in other laboratories. However, there is increasing benefit to formalizing the descriptions of protocols, as laboratory automation systems (such as microfluidic chips) are becoming increasingly capable of executing them. Our goal in this paper is to improve both the reproducibility and automation of biology experiments by using a programming language to express the precise series of steps taken. Results We have developed BioCoder, a C++ library that enables biologists to express the exact steps needed to execute a protocol. In addition to being suitable for automation, BioCoder converts the code into a readable, English-language description for use by biologists. We have implemented over 65 protocols in BioCoder; the most complex of these was successfully executed by a biologist in the laboratory using BioCoder as the only reference. We argue that BioCoder exposes and resolves ambiguities in existing protocols, and could provide the software foundations for future automation platforms. BioCoder is freely available for download at http://research.microsoft.com/en-us/um/india/projects/biocoder/. Conclusions BioCoder represents the first practical programming system for standardizing and automating biology protocols. Our vision is to change the way that experimental methods are communicated: rather than publishing a written account of the protocols used, researchers will simply publish the code. Our experience suggests that this practice is tractable and offers many benefits. We invite other researchers to leverage BioCoder to improve the precision and completeness of their protocols, and also to adapt and extend BioCoder to new domains. PMID:21059251

  8. FIELD SAMPLING PROTOCOLS AND ANALYSIS

    EPA Science Inventory

    I have been asked to speak again to the environmental science class regarding actual research scenarios related to my work at Kerr Lab. I plan to discuss sampling protocols along with various field analyses performed during sampling activities. Many of the students have never see...

  9. A Student Teamwork Induction Protocol

    ERIC Educational Resources Information Center

    Kamau, Caroline; Spong, Abigail

    2015-01-01

    Faulty group processes have harmful effects on performance but there is little research about intervention protocols to pre-empt them in higher education. This naturalistic experiment compared a control cohort with an inducted cohort. The inducted cohort attended a workshop, consultations, elected a leader and used tools (a group log and group…

  10. Bundle Security Protocol for ION

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.; Birrane, Edward J.; Krupiarz, Christopher

    2011-01-01

    This software implements bundle authentication, conforming to the Delay-Tolerant Networking (DTN) Internet Draft on Bundle Security Protocol (BSP), for the Interplanetary Overlay Network (ION) implementation of DTN. This is the only implementation of BSP that is integrated with ION.

  11. Quantum cryptography: individual eavesdropping with the knowledge of the error-correcting protocol

    SciTech Connect

    Horoshko, D B

    2007-12-31

    The quantum key distribution protocol BB84 combined with the repetition protocol for error correction is analysed from the point of view of its security against individual eavesdropping relying on quantum memory. It is shown that the mere knowledge of the error-correcting protocol changes the optimal attack and provides the eavesdropper with additional information on the distributed key. (fifth seminar in memory of d.n. klyshko)

  12. An Improved RSA Based User Authentication and Session Key Agreement Protocol Usable in TMIS.

    PubMed

    Amin, Ruhul; Biswas, G P

    2015-08-01

    Recently, Giri et al.'s proposed a RSA cryptosystem based remote user authentication scheme for telecare medical information system and claimed that the protocol is secure against all the relevant security attacks. However, we have scrutinized the Giri et al.'s protocol and pointed out that the protocol is not secure against off-line password guessing attack, privileged insider attack and also suffers from anonymity problem. Moreover, the extension of password guessing attack leads to more security weaknesses. Therefore, this protocol needs improvement in terms of security before implementing in real-life application. To fix the mentioned security pitfalls, this paper proposes an improved scheme over Giri et al.'s scheme, which preserves user anonymity property. We have then simulated the proposed protocol using widely-accepted AVISPA tool which ensures that the protocol is SAFE under OFMC and CL-AtSe models, that means the same protocol is secure against active and passive attacks including replay and man-in-the-middle attacks. The informal cryptanalysis has been also presented, which confirmed that the proposed protocol provides well security protection on the relevant security attacks. The performance analysis section compares the proposed protocol with other existing protocols in terms of security and it has been observed that the protocol provides more security and achieves additional functionalities such as user anonymity and session key verification.

  13. An Improved RSA Based User Authentication and Session Key Agreement Protocol Usable in TMIS.

    PubMed

    Amin, Ruhul; Biswas, G P

    2015-08-01

    Recently, Giri et al.'s proposed a RSA cryptosystem based remote user authentication scheme for telecare medical information system and claimed that the protocol is secure against all the relevant security attacks. However, we have scrutinized the Giri et al.'s protocol and pointed out that the protocol is not secure against off-line password guessing attack, privileged insider attack and also suffers from anonymity problem. Moreover, the extension of password guessing attack leads to more security weaknesses. Therefore, this protocol needs improvement in terms of security before implementing in real-life application. To fix the mentioned security pitfalls, this paper proposes an improved scheme over Giri et al.'s scheme, which preserves user anonymity property. We have then simulated the proposed protocol using widely-accepted AVISPA tool which ensures that the protocol is SAFE under OFMC and CL-AtSe models, that means the same protocol is secure against active and passive attacks including replay and man-in-the-middle attacks. The informal cryptanalysis has been also presented, which confirmed that the proposed protocol provides well security protection on the relevant security attacks. The performance analysis section compares the proposed protocol with other existing protocols in terms of security and it has been observed that the protocol provides more security and achieves additional functionalities such as user anonymity and session key verification. PMID:26123833

  14. 21 CFR 660.46 - Samples; protocols; official release.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Samples; protocols; official release. 660.46 Section 660.46 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B...

  15. 21 CFR 660.46 - Samples; protocols; official release.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Samples; protocols; official release. 660.46 Section 660.46 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B...

  16. 21 CFR 660.6 - Samples; protocols; official release.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Samples; protocols; official release. 660.6 Section 660.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Antibody to Hepatitis...

  17. 21 CFR 660.46 - Samples; protocols; official release.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Samples; protocols; official release. 660.46 Section 660.46 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B...

  18. 21 CFR 660.46 - Samples; protocols; official release.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Samples; protocols; official release. 660.46 Section 660.46 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B...

  19. 21 CFR 660.46 - Samples; protocols; official release.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Samples; protocols; official release. 660.46 Section 660.46 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B...

  20. Bell Inequalities, Experimental Protocols and Contextuality

    NASA Astrophysics Data System (ADS)

    Kupczynski, Marian

    2015-07-01

    In this paper we give additional arguments in favor of the point of view that the violation of Bell, CHSH and CH inequalities is not due to a mysterious non locality of nature. We concentrate on an intimate relation between a protocol of a random experiment and a probabilistic model which is used to describe it. We discuss in a simple way differences between attributive joint probability distributions and generalized joint probability distributions of outcomes from distant experiments which depend on how the pairing of these outcomes is defined. We analyze in detail experimental protocols implied by local realistic and stochastic hidden variable models and show that they are incompatible with the protocols used in spin polarization correlation experiments. We discuss also the meaning of "free will", differences between quantum and classical filters, contextuality of Kolmogorov models, contextuality of quantum theory (QT) and show how this contextuality has to be taken into account in probabilistic models trying to explain in an intuitive way the predictions of QT. The long range imperfect correlations between the clicks of distant detectors can be explained by partially preserved correlations between the signals created by a source. These correlations can only be preserved if the clicks are produced in a local and deterministic way depending on intrinsic parameters describing signals and measuring devices in the moment of the measurement. If an act of a measurement was irreducibly random they would be destroyed. It seems to indicate that QT may be in fact emerging from some underlying more detailed theory of physical phenomena. If this was a case then there is a chance to find in time series of experimental data some fine structures not predicted by QT. This would be a major discovery because it would not only prove that QT does not provide a complete description of individual physical systems but it would prove that it is not predictably complete.

  1. Real-Time QoS Routing Protocols in Wireless Multimedia Sensor Networks: Study and Analysis.

    PubMed

    Alanazi, Adwan; Elleithy, Khaled

    2015-09-02

    Many routing protocols have been proposed for wireless sensor networks. These routing protocols are almost always based on energy efficiency. However, recent advances in complementary metal-oxide semiconductor (CMOS) cameras and small microphones have led to the development of Wireless Multimedia Sensor Networks (WMSN) as a class of wireless sensor networks which pose additional challenges. The transmission of imaging and video data needs routing protocols with both energy efficiency and Quality of Service (QoS) characteristics in order to guarantee the efficient use of the sensor nodes and effective access to the collected data. Also, with integration of real time applications in Wireless Senor Networks (WSNs), the use of QoS routing protocols is not only becoming a significant topic, but is also gaining the attention of researchers. In designing an efficient QoS routing protocol, the reliability and guarantee of end-to-end delay are critical events while conserving energy. Thus, considerable research has been focused on designing energy efficient and robust QoS routing protocols. In this paper, we present a state of the art research work based on real-time QoS routing protocols for WMSNs that have already been proposed. This paper categorizes the real-time QoS routing protocols into probabilistic and deterministic protocols. In addition, both categories are classified into soft and hard real time protocols by highlighting the QoS issues including the limitations and features of each protocol. Furthermore, we have compared the performance of mobility-aware query based real-time QoS routing protocols from each category using Network Simulator-2 (NS2). This paper also focuses on the design challenges and future research directions as well as highlights the characteristics of each QoS routing protocol.

  2. Real-Time QoS Routing Protocols in Wireless Multimedia Sensor Networks: Study and Analysis

    PubMed Central

    Alanazi, Adwan; Elleithy, Khaled

    2015-01-01

    Many routing protocols have been proposed for wireless sensor networks. These routing protocols are almost always based on energy efficiency. However, recent advances in complementary metal-oxide semiconductor (CMOS) cameras and small microphones have led to the development of Wireless Multimedia Sensor Networks (WMSN) as a class of wireless sensor networks which pose additional challenges. The transmission of imaging and video data needs routing protocols with both energy efficiency and Quality of Service (QoS) characteristics in order to guarantee the efficient use of the sensor nodes and effective access to the collected data. Also, with integration of real time applications in Wireless Senor Networks (WSNs), the use of QoS routing protocols is not only becoming a significant topic, but is also gaining the attention of researchers. In designing an efficient QoS routing protocol, the reliability and guarantee of end-to-end delay are critical events while conserving energy. Thus, considerable research has been focused on designing energy efficient and robust QoS routing protocols. In this paper, we present a state of the art research work based on real-time QoS routing protocols for WMSNs that have already been proposed. This paper categorizes the real-time QoS routing protocols into probabilistic and deterministic protocols. In addition, both categories are classified into soft and hard real time protocols by highlighting the QoS issues including the limitations and features of each protocol. Furthermore, we have compared the performance of mobility-aware query based real-time QoS routing protocols from each category using Network Simulator-2 (NS2). This paper also focuses on the design challenges and future research directions as well as highlights the characteristics of each QoS routing protocol. PMID:26364639

  3. Implementation and evaluation of a protocol management system for automated review of CT protocols.

    PubMed

    Grimes, Joshua; Leng, Shuai; Zhang, Yi; Vrieze, Thomas; McCollough, Cynthia

    2016-09-08

    Protocol review is important to decrease the risk of patient injury and increase the consistency of CT image quality. A large volume of CT protocols makes manual review labor-intensive, error-prone, and costly. To address these challenges, we have developed a software system for automatically managing and monitoring CT proto-cols on a frequent basis. This article describes our experiences in the implementation and evaluation of this protocol monitoring system. In particular, we discuss various strategies for addressing each of the steps in our protocol-monitoring workflow, which are: maintaining an accurate set of master protocols, retrieving protocols from the scanners, comparing scanner protocols to master protocols, reviewing flagged differences between the scanner and master protocols, and updating the scanner and/or master protocols. In our initial evaluation focusing only on abdo-men and pelvis protocols, we detected 309 modified protocols in a 24-week trial period. About one-quarter of these modified protocols were determined to contain inappropriate (i.e., erroneous) protocol parameter modifications that needed to be corrected on the scanner. The most frequently affected parameter was the series description, which was inappropriately modified 47 times. Two inappropriate modifications were made to the tube current, which is particularly important to flag as this parameter impacts both radiation dose and image quality. The CT protocol changes detected in this work provide strong motivation for the use of an automated CT protocol quality control system to ensure protocol accuracy and consistency.

  4. Implementation and evaluation of a protocol management system for automated review of CT protocols.

    PubMed

    Grimes, Joshua; Leng, Shuai; Zhang, Yi; Vrieze, Thomas; McCollough, Cynthia

    2016-01-01

    Protocol review is important to decrease the risk of patient injury and increase the consistency of CT image quality. A large volume of CT protocols makes manual review labor-intensive, error-prone, and costly. To address these challenges, we have developed a software system for automatically managing and monitoring CT proto-cols on a frequent basis. This article describes our experiences in the implementation and evaluation of this protocol monitoring system. In particular, we discuss various strategies for addressing each of the steps in our protocol-monitoring workflow, which are: maintaining an accurate set of master protocols, retrieving protocols from the scanners, comparing scanner protocols to master protocols, reviewing flagged differences between the scanner and master protocols, and updating the scanner and/or master protocols. In our initial evaluation focusing only on abdo-men and pelvis protocols, we detected 309 modified protocols in a 24-week trial period. About one-quarter of these modified protocols were determined to contain inappropriate (i.e., erroneous) protocol parameter modifications that needed to be corrected on the scanner. The most frequently affected parameter was the series description, which was inappropriately modified 47 times. Two inappropriate modifications were made to the tube current, which is particularly important to flag as this parameter impacts both radiation dose and image quality. The CT protocol changes detected in this work provide strong motivation for the use of an automated CT protocol quality control system to ensure protocol accuracy and consistency. PMID:27685112

  5. Mutagenesis protocols in Saccharomyces cerevisiae by in vivo overlap extension.

    PubMed

    Alcalde, Miguel

    2010-01-01

    A high recombination frequency and its ease of manipulation has made Saccharomyces cerevisiae a unique model eukaryotic organism to study homologous recombination. Indeed, the well-developed recombination machinery in S. cerevisiae facilitates the construction of mutant libraries for directed evolution experiments. In this context, in vivo overlap extension (IVOE) is a particularly attractive protocol that takes advantage of the eukaryotic apparatus to carry out combinatorial saturation mutagenesis, site-directed recombination or site-directed mutagenesis, avoiding ligation steps and additional PCR reactions that are common to standard in vitro protocols. PMID:20676972

  6. Numerical analysis of decoy state quantum key distribution protocols

    SciTech Connect

    Harrington, Jim W; Rice, Patrick R

    2008-01-01

    Decoy state protocols are a useful tool for many quantum key distribution systems implemented with weak coherent pulses, allowing significantly better secret bit rates and longer maximum distances. In this paper we present a method to numerically find optimal three-level protocols, and we examine how the secret bit rate and the optimized parameters are dependent on various system properties, such as session length, transmission loss, and visibility. Additionally, we show how to modify the decoy state analysis to handle partially distinguishable decoy states as well as uncertainty in the prepared intensities.

  7. Chapter 14: Chiller Evaluation Protocol

    SciTech Connect

    Tiessen, A.

    2014-09-01

    This protocol defines a chiller measure as a project that directly impacts equipment within the boundary of a chiller plant. A chiller plant encompasses a chiller--or multiple chillers--and associated auxiliary equipment. This protocol primarily covers electric-driven chillers and chiller plants. It does not include thermal energy storage and absorption chillers fired by natural gas or steam, although a similar methodology may be applicable to these chilled water system components. Chillers provide mechanical cooling for commercial, institutional, multiunit residential, and industrial facilities. Cooling may be required for facility heating, ventilation, and air conditioning systems or for process cooling loads (e.g., data centers, manufacturing process cooling). The vapor compression cycle, or refrigeration cycle, cools water in the chilled water loop by absorbing heat and rejecting it to either a condensing water loop (water cooled chillers) or to the ambient air (air-cooled chillers).

  8. Neonatal euthanasia: The Groningen Protocol.

    PubMed

    Vizcarrondo, Felipe E

    2014-11-01

    For the past thirty years, voluntary euthanasia and physician-assisted suicide of adult patients have been common practice in the Netherlands. Neonatal euthanasia was recently legalized in the Netherlands and the Groningen Protocol (GP) was developed to regulate the practice. Supporters claim compliance with the GP criteria makes neonatal euthanasia ethically permissible. An examination of the criteria used by the Protocol to justify the euthanasia of seriously ill neonates reveals the criteria are not based on firm moral principles. The taking of the life of a seriously ill person is not the solution to the pain and suffering of the dying process. It is the role of the medical professional to care for the ailing patient with love and compassion, always preserving the person's dignity. Neonatal euthanasia is not ethically permissible. PMID:25473136

  9. Building America House Simulation Protocols

    SciTech Connect

    Hendron, Robert; Engebrecht, Cheryn

    2010-09-01

    The House Simulation Protocol document was developed to track and manage progress toward Building America's multi-year, average whole-building energy reduction research goals for new construction and existing homes, using a consistent analytical reference point. This report summarizes the guidelines for developing and reporting these analytical results in a consistent and meaningful manner for all home energy uses using standard operating conditions.

  10. Multiple protocol fluorometer and method

    DOEpatents

    Kolber, Zbigniew S.; Falkowski, Paul G.

    2000-09-19

    A multiple protocol fluorometer measures photosynthetic parameters of phytoplankton and higher plants using actively stimulated fluorescence protocols. The measured parameters include spectrally-resolved functional and optical absorption cross sections of PSII, extent of energy transfer between reaction centers of PSII, F.sub.0 (minimal), F.sub.m (maximal) and F.sub.v (variable) components of PSII fluorescence, photochemical and non-photochemical quenching, size of the plastoquinone (PQ) pool, and the kinetics of electron transport between Q.sub.a and PQ pool and between PQ pool and PSI. The multiple protocol fluorometer, in one embodiment, is equipped with an excitation source having a controlled spectral output range between 420 nm and 555 nm and capable of generating flashlets having a duration of 0.125-32 .mu.s, an interval between 0.5 .mu.s and 2 seconds, and peak optical power of up to 2 W/cm.sup.2. The excitation source is also capable of generating, simultaneous with the flashlets, a controlled continuous, background illumination.

  11. The reliable multicast protocol application programming interface

    NASA Technical Reports Server (NTRS)

    Montgomery , Todd; Whetten, Brian

    1995-01-01

    The Application Programming Interface for the Berkeley/WVU implementation of the Reliable Multicast Protocol is described. This transport layer protocol is implemented as a user library that applications and software buses link against.

  12. Integrating protocol schedules with patients' personal calendars.

    PubMed

    Civan, Andrea; Gennari, John H; Pratt, Wanda

    2006-01-01

    We propose a new approach for integrating protocol care schedules into patients' personal calendars. This approach could provide patients with greater control over their current and future scheduling demands as they seek and receive protocol-based care. PMID:17238511

  13. A Wiki Based CT Protocol Management System.

    PubMed

    Szczykutowicz, Timothy P; Rubert, Nicholas; Belden, Daryn; Ciano, Amanda; Duplissis, Andrew; Hermanns, Ashley; Monette, Stephen; Saldivar, Elliott Janssen

    2015-01-01

    At the University of Wisconsin Madison Department of Radiology, CT protocol management requires maintenance of thousands of parameters for each scanner. Managing CT protocols is further complicated by the unique configurability of each scanner. Due to recent Joint Commission requirements, now all CT protocol changes must be documented and reviewed by a site's CT protocol optimization team. The difficulty of managing the CT protocols was not in assembling the protocols, but in managing and implementing changes. This is why a wiki based solution for protocol management was implemented. A wiki inherently keeps track of all changes, logging who made the changes and when, allowing for editing and viewing permissions to be controlled, as well as allowing protocol changes to be instantly relayed to all scanner locations.

  14. Developing family planning nurse practitioner protocols.

    PubMed

    Hawkins, J W; Roberto, D

    1984-01-01

    This article focuses on the process of development of protocols for family planning nurse practitioners. A rationale for the use of protocols, a definition of the types and examples, and the pros and cons of practice with protocols are presented. A how-to description for the development process follows, including methods and a suggested tool for critique and evaluation. The aim of the article is to assist nurse practitioners in developing protocols for their practice.

  15. Protocols for the In Silico Design of RNA Nanostructures

    NASA Astrophysics Data System (ADS)

    Shapiro, Bruce A.; Bindewald, Eckart; Kasprzak, Wojciech; Yingling, Yaroslava

    Recent developments in the field of nanobiology have significantly expanded the possibilities for new modalities in the treatment of many diseases, including cancer. Ribonucleic acid (RNA) represents a relatively new molecular material for the development of these biologically oriented nanodevices. In addition, RNA nanobiology presents a relatively new approach for the development of RNA-based nanoparticles that can be used as crystallization substrates and scaffolds for RNA-based nanoarrays. Presented in this chapter are some methodological shaped-based protocols for the design of such RNA nanostructures. Included are descriptions and background materials describing protocols that use a database of three-dimensional RNA structure motifs; designed RNA secondary structure motifs; and a combination of the two approaches. An example is also given illustrating one of the protocols.

  16. Message Protocols for Provisioning and Usage of Computing Services

    NASA Astrophysics Data System (ADS)

    Borissov, Nikolay; Caton, Simon; Rana, Omer; Levine, Aharon

    The commercial availability of computational resources enable consumers to scale their applications on-demand. However, it is necessary for both consumers and providers of computational resources to express their technical and economic preferences using common language protocols. Ultimately, this requires clear, flexible and pragmatic communication protocols and policies for the expression of bids and resulting generation of service level agreements (SLAs). Further standardization efforts in such description languages will foster the specification of common interfaces and matching rules for establishing SLAs. Grid middleware are not compatible with market-orientated resource provisioning. We aim to reduce this gap by defining extensions to a standardized specification such as JSDL. Furthermore, we present a methodology for matchmaking consumer bids and provider offers and map the additional economic attributes into a SLA. We demonstrate the usage of the message protocols in an application scenario.

  17. Future directions in packet radio architectures and protocols

    NASA Astrophysics Data System (ADS)

    Shacham, Nachum; Westcott, Jil

    1987-01-01

    The technology of packet switching over multihop, multiple-access channels has evolved to the point at which its protocols can now support internetwork operation of medium-size networks whose nodes possess some degree of mobility. As regards the needs and challenges of the future operating environment, it is clear that these can be met only by enhancing the packet radio architecture and its protocols. Several enhancements that allow the organization of large, dynamic networks that can operate over multiple channels, adapt to varying conditions, and possess self-monitoring and self-control capabilities are discussed. As these areas are examined, the attendant issues and tradeoffs are discussed; in addition, some protocols and information regarding their performance are presented.

  18. A Signcryption based Light Weight Key Exchange Protocol

    NASA Astrophysics Data System (ADS)

    Feng, Yong; Wei, Qian; Zhang, Xing

    Traditional cryptography based authenticated Diffie-Hellman key exchange protocols expose the problems of efficiency and privacy since signature-then-encryption is heavy to wireless communication special for flexible dynamic deployment, i.e., wireless mesh networks, wireless sensor networks, mobile ad hoc networks, etc., in computational cost and communicational overhead and traditional digital signature allows anyone to verify its validity using the corresponding public key. In this paper, we propose a signcryption based light weight key exchange protocol named SLWKE which can provide resistance to traditional attacks, i.e., eavesdropping, deducing, replaying, interleaving, forging and repudiating, and unknown key-share attack and save computational cost by three modular calculations, i.e., one modular inversion, one modular addition and one modular multiplicative, included in a signature s and communicational overhead by secure length of IqI in comparison to signcryption based direct key exchange using a time-stamp protocol termed Dkeuts.

  19. Identity-based authenticated key exchange protocols from the Tate pairing

    NASA Astrophysics Data System (ADS)

    Shen, Jun; Jin, Hong; Yang, Zhiyong; Cui, Xiang

    2011-12-01

    Key agreement protocols are designed to establish a session keys between two or multiple entities oven an insecure network and the session key is used to assure confidentiality thought encryption. With the advantages of identity-based (ID-based) cryptography, there have been many ID-based key agreement protocols proposed. However, most of them are based on Weil pairing, which is more cost of computation compared with Tate paring. In this paper, we propose a newly ID-based key agreement protocol from the Tate pairing. Compared with previous protocols, the new protocol minimizes the cost of computation with no extra message exchange time. In addition, the proposed protocol provides known key security, no key control, no key-compromise impersonation and perfect forward secrecy.

  20. Building a flexible protocol information system with ready for use' web-technology.

    PubMed

    Vissers, M C; Hasman, A

    1999-01-01

    This paper describes how web technology, currently available, can be used to build a fast and easy flexible protocol information system. The interface design and functionalities of the system were based on experiences with a previous version of a protocol information system (ProtoVIEW). A wide range of diagnostic or therapeutic protocols could be retrieved and viewed with ProtoVIEW. The Web-based version contains all functionalities of the non web-based version plus several new functionalities. The web version contains an X-ray viewer and a great deal of interactivity such as validation of electronic patient data forms. The most important additional function is the context sensitive protocol support that may lead to improved protocol adherence. Finally, the web-based version can be accessed from any working place since patient data and protocols are stored centrally.

  1. 40 CFR 792.120 - Protocol.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false Protocol. 792.120 Section 792.120 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Protocol for and Conduct of A Study § 792.120 Protocol. (a)...

  2. Cryptanalysis on Cheng et al. protocol

    NASA Astrophysics Data System (ADS)

    Thakur, Tejeshwari

    2016-06-01

    Deployment of new node in any wireless sensor network is a sensitive task. This is the reason why, an Access Control Protocol is required in WSN. In this paper, we demonstrate that Access Control Protocol proposed by Cheng et al.[1] for Wireless Sensor Network is insecure. The reason is that this protocol fails to resist the active attack.

  3. 21 CFR 312.83 - Treatment protocols.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Treatment protocols. 312.83 Section 312.83 Food...-debilitating Illnesses § 312.83 Treatment protocols. If the preliminary analysis of phase 2 test results appears promising, FDA may ask the sponsor to submit a treatment protocol to be reviewed under...

  4. 21 CFR 312.83 - Treatment protocols.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Treatment protocols. 312.83 Section 312.83 Food...-debilitating Illnesses § 312.83 Treatment protocols. If the preliminary analysis of phase 2 test results appears promising, FDA may ask the sponsor to submit a treatment protocol to be reviewed under...

  5. 21 CFR 312.83 - Treatment protocols.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Treatment protocols. 312.83 Section 312.83 Food...-debilitating Illnesses § 312.83 Treatment protocols. If the preliminary analysis of phase 2 test results appears promising, FDA may ask the sponsor to submit a treatment protocol to be reviewed under...

  6. 21 CFR 312.83 - Treatment protocols.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Treatment protocols. 312.83 Section 312.83 Food...-debilitating Illnesses § 312.83 Treatment protocols. If the preliminary analysis of phase 2 test results appears promising, FDA may ask the sponsor to submit a treatment protocol to be reviewed under...

  7. New practical treadmill protocol for clinical use.

    PubMed

    Wolthuis, R A; Froelicher, V F; Fischer, J; Noguera, I; Davis, G; Stewart, A J; Triebwasser, J H

    1977-05-01

    A new continuous treadmill protocol (USAFSAM) has been designed using a constant treadmill speed (3.3 miles/hour) and regular equal increments in treadmill grade (5%/3min). The constant treadmill speed requires only initial adaptation in patient stride, reduces technician adjustments and produces less electrocardiographic motion artifact than do protocols using multiple or higher treadmill speeds, or both. The regular equal increments in treadmill grade are easy to implement and provide a larger number of work loads than do protocols that are discontinuous or require larger changes in work load. The USAFSAM protocol was compared with the older Balke-Ware protocol in 26 healthy men (aged 30 to 59 years). Each fasting subject completed two maximal treadmill tests from each protocol. Measurements included minute heart rate from the electrocardiogram, auscultatory blood pressures and oxygen consumption obtained with standard techniques. Similarities in between-protocol measurements for submaximal and maximal treadmill efforts were impressive; differences were small and unimportant. Further, both protocols showed equal reproducibility for the measurements noted. Importantly, time to maximal effort was reduced by 24% with the USAFSAM protocol. The USAFSAM treadmill protocol has since been used in more than 500 clinical and screening examinations, thus confirming its advantages and practicality for routine clinical stress testing. Normal reference values previously established for the Balke-Ware protocol are shown to apply to the new USAFSAM protocol as well. PMID:857630

  8. Phenology monitoring protocol: Northeast Temperate Network

    USGS Publications Warehouse

    Tierney, Geri; Mitchell, Brian; Miller-Rushing, Abraham J.; Katz, Jonathan; Denny, Ellen; Brauer, Corinne; Donovan, Therese; Richardson, Andrew D.; Toomey, Michael; Kozlowski, Adam; Weltzin, Jake F.; Gerst, Kathy; Sharron, Ed; Sonnentag, Oliver; Dieffenbach, Fred

    2013-01-01

    historical parks and national historic sites in the northeastern US. This protocol was developed in collaboration with and relies upon the procedures and infrastructure of the USA National Phenology Network (USA-NPN), including Nature’s Notebook, USA-NPN’s online plant and animal phenology observation program (www.nn.usanpn.org). Organized in 2007, USA-NPN is a nation-wide partnership among federal agencies, schools and universities, citizen volunteers, and others to monitor and understand the influence of seasonal cycles on the nation’s biological resources. The overall goal of NETN’s phenology monitoring program is to determine trends in the phenology of key species in order to assist park managers with the detection and mitigation of the effects of climate change on park resources. An additional programmatic goal is to interest and educate park visitors and staff, as well as a cadre of volunteer monitors.

  9. [Food additives and healthiness].

    PubMed

    Heinonen, Marina

    2014-01-01

    Additives are used for improving food structure or preventing its spoilage, for example. Many substances used as additives are also naturally present in food. The safety of additives is evaluated according to commonly agreed principles. If high concentrations of an additive cause adverse health effects for humans, a limit of acceptable daily intake (ADI) is set for it. An additive is a risk only when ADI is exceeded. The healthiness of food is measured on the basis of nutrient density and scientifically proven effects.

  10. On the vulnerability of basic quantum key distribution protocols and three protocols stable to attack with 'blinding' of avalanche photodetectors

    SciTech Connect

    Molotkov, S. N.

    2012-05-15

    The fundamental quantum mechanics prohibitions on the measurability of quantum states allow secure key distribution between spatially remote users to be performed. Experimental and commercial implementations of quantum cryptography systems, however, use components that exist at the current technology level, in particular, one-photon avalanche photodetectors. These detectors are subject to the blinding effect. It was shown that all the known basic quantum key distribution protocols and systems based on them are vulnerable to attacks with blinding of photodetectors. In such attacks, an eavesdropper knows all the key transferred, does not produce errors at the reception side, and remains undetected. Three protocols of quantum key distribution stable toward such attacks are suggested. The security of keys and detection of eavesdropping attempts are guaranteed by the internal structure of protocols themselves rather than additional technical improvements.

  11. Low-cost, low-input RNA-seq protocols perform nearly as well as high-input protocols

    PubMed Central

    Eisen, Michael B.

    2015-01-01

    Recently, a number of protocols extending RNA-sequencing to the single-cell regime have been published. However, we were concerned that the additional steps to deal with such minute quantities of input sample would introduce serious biases that would make analysis of the data using existing approaches invalid. In this study, we performed a critical evaluation of several of these low-volume RNA-seq protocols, and found that they performed slightly less well in per-gene linearity of response, but with at least two orders of magnitude less sample required. We also explored a simple modification to one of these protocols that, for many samples, reduced the cost of library preparation to approximately $20/sample. PMID:25834775

  12. Reactive broadcasting protocol for video on demand

    NASA Astrophysics Data System (ADS)

    Paris, Jehan-Francois; Carter, Steven W.; Long, Darrell D. E.

    1999-12-01

    We propose a reactive broadcasting protocol that addresses the problem of distributing moderately popular videos in a more efficient fashion. Like all efficient broadcasting protocols, reactive broadcasting assumes that the customer set-top box has enough local storage to store at least one half of each video being watched. Unlike other broadcasting protocols, reactive broadcasting only broadcasts the later portions of each video. the initial segment of each video is distributed on demand using a stream tapping protocol. Our simulations show that reactive broadcasting outperforms both conventional broadcasting protocols and pure stream tapping for a wide range of video request rates.

  13. INEEL AIR MODELING PROTOCOL ext

    SciTech Connect

    C. S. Staley; M. L. Abbott; P. D. Ritter

    2004-12-01

    Various laws stemming from the Clean Air Act of 1970 and the Clean Air Act amendments of 1990 require air emissions modeling. Modeling is used to ensure that air emissions from new projects and from modifications to existing facilities do not exceed certain standards. For radionuclides, any new airborne release must be modeled to show that downwind receptors do not receive exposures exceeding the dose limits and to determine the requirements for emissions monitoring. For criteria and toxic pollutants, emissions usually must first exceed threshold values before modeling of downwind concentrations is required. This document was prepared to provide guidance for performing environmental compliance-driven air modeling of emissions from Idaho National Engineering and Environmental Laboratory facilities. This document assumes that the user has experience in air modeling and dose and risk assessment. It is not intended to be a "cookbook," nor should all recommendations herein be construed as requirements. However, there are certain procedures that are required by law, and these are pointed out. It is also important to understand that air emissions modeling is a constantly evolving process. This document should, therefore, be reviewed periodically and revised as needed. The document is divided into two parts. Part A is the protocol for radiological assessments, and Part B is for nonradiological assessments. This document is an update of and supersedes document INEEL/INT-98-00236, Rev. 0, INEEL Air Modeling Protocol. This updated document incorporates changes in some of the rules, procedures, and air modeling codes that have occurred since the protocol was first published in 1998.

  14. Planetary Protection Alternate Protocol Certification

    NASA Astrophysics Data System (ADS)

    Baker, Amy; Barengoltz, Jack; Tisdale, David

    The talk presents a standardized approach for new method certification or alterative testing protocol (ATP) certification against the existing U.S. Planetary Protection Standards. In consideration of new method certification there are two phases of activities that are relevant to the certification process. The first is sample acquisition which typically incorporates swab or wipes sampling on relevant hardware, associated facilities and ground support equipment. The sampling methods introduce considerations of field sampling efficiency as it relates to spore distribution on the spacecraft, spacecraft material influences on the ability of the swab or wipe to remove spores from the hardware, the types of swabs and wipes used (polyester, cotton, macrofoam), and human sampling influences. The second portion of a new protocol certification looks specifically at the lab work-up or analysis of the samples provided to the laboratory. Variables in this process include selection of appropriate biomarkers, extraction efficiencies (removal of spores or constituents of interest from the sampling device), and a method's ability to accurately determine the number of spores present in the sample with a statistically valid level of confidence as described by parameters such as precision, accuracy, robustness, specificity and sensitivity. Considerations for alternative testing protocols such as those which utilize bioburden reduction techniques include selection of appropriate biomarkers for testing, test materials and a defined statistical approach that provides sufficient scientific data to support the modification of an existing NASA specification or the generation of a new NASA specification. Synergies between the U.S. and European Space Agency approaches will also be discussed.

  15. Protocolized Resuscitation of Burn Patients.

    PubMed

    Cancio, Leopoldo C; Salinas, Jose; Kramer, George C

    2016-10-01

    Fluid resuscitation of burn patients is commonly initiated using modified Brooke or Parkland formula. The fluid infusion rate is titrated up or down hourly to maintain adequate urine output and other endpoints. Over-resuscitation leads to morbid complications. Adherence to paper-based protocols, flow sheets, and clinical practice guidelines is associated with decreased fluid resuscitation volumes and complications. Computerized tools assist providers. Although completely autonomous closed-loop control of resuscitation has been demonstrated in animal models of burn shock, the major advantages of open-loop and decision-support systems are identifying trends, enhancing situational awareness, and encouraging burn team communication. PMID:27600131

  16. A structured data transfer protocol

    NASA Technical Reports Server (NTRS)

    Barrett, P.; Rots, A.

    1992-01-01

    The transfer of data between different computers and programs can be a major obstacle during data analysis. We present a new data transfer protocol which is based on a simple structure containing a value, an error, and a unit. Each of these members can be arrays or another structure. The ability to nest structures allows for the concept of objects. When using an object-oriented language such as C++, reference can be made to the object name instead of each element explicitly. Prototype code has been written which implements the basic design with enhancements planned for the future.

  17. Mars Sample Quarantine Protocol Workshop

    NASA Technical Reports Server (NTRS)

    DeVincenzi, Donald L. (Editor); Bagby, John (Editor); Race, Margaret (Editor); Rummel, John (Editor)

    1999-01-01

    The Mars Sample Quarantine Protocol (QP) Workshop was convened to deal with three specific aspects of the initial handling of a returned Mars sample: 1) biocontainment, to prevent uncontrolled release of sample material into the terrestrial environment; 2) life detection, to examine the sample for evidence of live organisms; and 3) biohazard testing, to determine if the sample poses any threat to terrestrial life forms and the Earth's biosphere. During the first part of the Workshop, several tutorials were presented on topics related to the workshop in order to give all participants a common basis in the technical areas necessary to achieve the objectives of the Workshop.

  18. Analyzing the effect of routing protocols on media access control protocols in radio networks

    SciTech Connect

    Barrett, C. L.; Drozda, M.; Marathe, A.; Marathe, M. V.

    2002-01-01

    We study the effect of routing protocols on the performance of media access control (MAC) protocols in wireless radio networks. Three well known MAC protocols: 802.11, CSMA, and MACA are considered. Similarly three recently proposed routing protocols: AODV, DSR and LAR scheme 1 are considered. The experimental analysis was carried out using GloMoSim: a tool for simulating wireless networks. The main focus of our experiments was to study how the routing protocols affect the performance of the MAC protocols when the underlying network and traffic parameters are varied. The performance of the protocols was measured w.r.t. five important parameters: (i) number of received packets, (ii) average latency of each packet, (iii) throughput (iv) long term fairness and (v) number of control packets at the MAC layer level. Our results show that combinations of routing and MAC protocols yield varying performance under varying network topology and traffic situations. The result has an important implication; no combination of routing protocol and MAC protocol is the best over all situations. Also, the performance analysis of protocols at a given level in the protocol stack needs to be studied not locally in isolation but as a part of the complete protocol stack. A novel aspect of our work is the use of statistical technique, ANOVA (Analysis of Variance) to characterize the effect of routing protocols on MAC protocols. This technique is of independent interest and can be utilized in several other simulation and empirical studies.

  19. Protocols for calibrating multibeam sonar.

    PubMed

    Foote, Kenneth G; Chu, Dezhang; Hammar, Terence R; Baldwin, Kenneth C; Mayer, Larry A; Hufnagle, Lawrence C; Jech, J Michael

    2005-04-01

    Development of protocols for calibrating multibeam sonar by means of the standard-target method is documented. Particular systems used in the development work included three that provide the water-column signals, namely the SIMRAD SM2000/90- and 200-kHz sonars and RESON SeaBat 8101 sonar, with operating frequency of 240 kHz. Two facilities were instrumented specifically for the work: a sea well at the Woods Hole Oceanographic Institution and a large, indoor freshwater tank at the University of New Hampshire. Methods for measuring the transfer characteristics of each sonar, with transducers attached, are described and illustrated with measurement results. The principal results, however, are the protocols themselves. These are elaborated for positioning the target, choosing the receiver gain function, quantifying the system stability, mapping the directionality in the plane of the receiving array and in the plane normal to the central axis, measuring the directionality of individual beams, and measuring the nearfield response. General preparations for calibrating multibeam sonars and a method for measuring the receiver response electronically are outlined. Advantages of multibeam sonar calibration and outstanding problems, such as that of validation of the performance of multibeam sonars as configured for use, are mentioned.

  20. Toward Synthesis, Analysis, and Certification of Security Protocols

    NASA Technical Reports Server (NTRS)

    Schumann, Johann

    2004-01-01

    Implemented security protocols are basically pieces of software which are used to (a) authenticate the other communication partners, (b) establish a secure communication channel between them (using insecure communication media), and (c) transfer data between the communication partners in such a way that these data only available to the desired receiver, but not to anyone else. Such an implementation usually consists of the following components: the protocol-engine, which controls in which sequence the messages of the protocol are sent over the network, and which controls the assembly/disassembly and processing (e.g., decryption) of the data. the cryptographic routines to actually encrypt or decrypt the data (using given keys), and t,he interface to the operating system and to the application. For a correct working of such a security protocol, all of these components must work flawlessly. Many formal-methods based techniques for the analysis of a security protocols have been developed. They range from using specific logics (e.g.: BAN-logic [4], or higher order logics [12] to model checking [2] approaches. In each approach, the analysis tries to prove that no (or at least not a modeled intruder) can get access to secret data. Otherwise, a scenario illustrating the &tack may be produced. Despite the seeming simplicity of security protocols ("only" a few messages are sent between the protocol partners in order to ensure a secure communication), many flaws have been detected. Unfortunately, even a perfect protocol engine does not guarantee flawless working of a security protocol, as incidents show. Many break-ins and security vulnerabilities are caused by exploiting errors in the implementation of the protocol engine or the underlying operating system. Attacks using buffer-overflows are a very common class of such attacks. Errors in the implementation of exception or error handling can open up additional vulnerabilities. For example, on a website with a log-in screen

  1. An Enhanced Biometric Based Authentication with Key-Agreement Protocol for Multi-Server Architecture Based on Elliptic Curve Cryptography

    PubMed Central

    Reddy, Alavalapati Goutham; Das, Ashok Kumar; Odelu, Vanga; Yoo, Kee-Young

    2016-01-01

    Biometric based authentication protocols for multi-server architectures have gained momentum in recent times due to advancements in wireless technologies and associated constraints. Lu et al. recently proposed a robust biometric based authentication with key agreement protocol for a multi-server environment using smart cards. They claimed that their protocol is efficient and resistant to prominent security attacks. The careful investigation of this paper proves that Lu et al.’s protocol does not provide user anonymity, perfect forward secrecy and is susceptible to server and user impersonation attacks, man-in-middle attacks and clock synchronization problems. In addition, this paper proposes an enhanced biometric based authentication with key-agreement protocol for multi-server architecture based on elliptic curve cryptography using smartcards. We proved that the proposed protocol achieves mutual authentication using Burrows-Abadi-Needham (BAN) logic. The formal security of the proposed protocol is verified using the AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our protocol can withstand active and passive attacks. The formal and informal security analyses and performance analysis demonstrates that the proposed protocol is robust and efficient compared to Lu et al.’s protocol and existing similar protocols. PMID:27163786

  2. An Enhanced Biometric Based Authentication with Key-Agreement Protocol for Multi-Server Architecture Based on Elliptic Curve Cryptography.

    PubMed

    Reddy, Alavalapati Goutham; Das, Ashok Kumar; Odelu, Vanga; Yoo, Kee-Young

    2016-01-01

    Biometric based authentication protocols for multi-server architectures have gained momentum in recent times due to advancements in wireless technologies and associated constraints. Lu et al. recently proposed a robust biometric based authentication with key agreement protocol for a multi-server environment using smart cards. They claimed that their protocol is efficient and resistant to prominent security attacks. The careful investigation of this paper proves that Lu et al.'s protocol does not provide user anonymity, perfect forward secrecy and is susceptible to server and user impersonation attacks, man-in-middle attacks and clock synchronization problems. In addition, this paper proposes an enhanced biometric based authentication with key-agreement protocol for multi-server architecture based on elliptic curve cryptography using smartcards. We proved that the proposed protocol achieves mutual authentication using Burrows-Abadi-Needham (BAN) logic. The formal security of the proposed protocol is verified using the AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our protocol can withstand active and passive attacks. The formal and informal security analyses and performance analysis demonstrates that the proposed protocol is robust and efficient compared to Lu et al.'s protocol and existing similar protocols.

  3. An Enhanced Biometric Based Authentication with Key-Agreement Protocol for Multi-Server Architecture Based on Elliptic Curve Cryptography.

    PubMed

    Reddy, Alavalapati Goutham; Das, Ashok Kumar; Odelu, Vanga; Yoo, Kee-Young

    2016-01-01

    Biometric based authentication protocols for multi-server architectures have gained momentum in recent times due to advancements in wireless technologies and associated constraints. Lu et al. recently proposed a robust biometric based authentication with key agreement protocol for a multi-server environment using smart cards. They claimed that their protocol is efficient and resistant to prominent security attacks. The careful investigation of this paper proves that Lu et al.'s protocol does not provide user anonymity, perfect forward secrecy and is susceptible to server and user impersonation attacks, man-in-middle attacks and clock synchronization problems. In addition, this paper proposes an enhanced biometric based authentication with key-agreement protocol for multi-server architecture based on elliptic curve cryptography using smartcards. We proved that the proposed protocol achieves mutual authentication using Burrows-Abadi-Needham (BAN) logic. The formal security of the proposed protocol is verified using the AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our protocol can withstand active and passive attacks. The formal and informal security analyses and performance analysis demonstrates that the proposed protocol is robust and efficient compared to Lu et al.'s protocol and existing similar protocols. PMID:27163786

  4. Model Checking a Byzantine-Fault-Tolerant Self-Stabilizing Protocol for Distributed Clock Synchronization Systems

    NASA Technical Reports Server (NTRS)

    Malekpour, Mahyar R.

    2007-01-01

    This report presents the mechanical verification of a simplified model of a rapid Byzantine-fault-tolerant self-stabilizing protocol for distributed clock synchronization systems. This protocol does not rely on any assumptions about the initial state of the system. This protocol tolerates bursts of transient failures, and deterministically converges within a time bound that is a linear function of the self-stabilization period. A simplified model of the protocol is verified using the Symbolic Model Verifier (SMV) [SMV]. The system under study consists of 4 nodes, where at most one of the nodes is assumed to be Byzantine faulty. The model checking effort is focused on verifying correctness of the simplified model of the protocol in the presence of a permanent Byzantine fault as well as confirmation of claims of determinism and linear convergence with respect to the self-stabilization period. Although model checking results of the simplified model of the protocol confirm the theoretical predictions, these results do not necessarily confirm that the protocol solves the general case of this problem. Modeling challenges of the protocol and the system are addressed. A number of abstractions are utilized in order to reduce the state space. Also, additional innovative state space reduction techniques are introduced that can be used in future verification efforts applied to this and other protocols.

  5. A Self-Stabilizing Distributed Clock Synchronization Protocol for Arbitrary Digraphs

    NASA Technical Reports Server (NTRS)

    Malekpour, Mahyar R.

    2011-01-01

    This report presents a self-stabilizing distributed clock synchronization protocol in the absence of faults in the system. It is focused on the distributed clock synchronization of an arbitrary, non-partitioned digraph ranging from fully connected to 1-connected networks of nodes while allowing for differences in the network elements. This protocol does not rely on assumptions about the initial state of the system, other than the presence of at least one node, and no central clock or a centrally generated signal, pulse, or message is used. Nodes are anonymous, i.e., they do not have unique identities. There is no theoretical limit on the maximum number of participating nodes. The only constraint on the behavior of the node is that the interactions with other nodes are restricted to defined links and interfaces. We present an outline of a deductive proof of the correctness of the protocol. A model of the protocol was mechanically verified using the Symbolic Model Verifier (SMV) for a variety of topologies. Results of the mechanical proof of the correctness of the protocol are provided. The model checking results have verified the correctness of the protocol as they apply to the networks with unidirectional and bidirectional links. In addition, the results confirm the claims of determinism and linear convergence. As a result, we conjecture that the protocol solves the general case of this problem. We also present several variations of the protocol and discuss that this synchronization protocol is indeed an emergent system.

  6. Evaluation and application of the strand-specific protocol for next-generation sequencing.

    PubMed

    Tsai, Kuo-Wang; Chang, Bill; Pan, Cheng-Tsung; Lin, Wei-Chen; Chen, Ting-Wen; Li, Sung-Chou

    2015-01-01

    Next-generation sequencing (NGS) has become a powerful sequencing tool, applied in a wide range of biological studies. However, the traditional sample preparation protocol for NGS is non-strand-specific (NSS), leading to biased estimates of expression for transcripts overlapped at the antisense strand. Strand-specific (SS) protocols have recently been developed. In this study, we prepared the same RNA sample by using the SS and NSS protocols, followed by sequencing with Illumina HiSeq platform. Using real-time quantitative PCR as a standard, we first proved that the SS protocol more precisely estimates gene expressions compared with the NSS protocol, particularly for those overlapped at the antisense strand. In addition, we also showed that the sequence reads from the SS protocol are comparable with those from conventional NSS protocols in many aspects. Finally, we also mapped a fraction of sequence reads back to the antisense strand of the known genes, originally without annotated genes located. Using sequence assembly and PCR validation, we succeeded in identifying and characterizing the novel antisense genes. Our results show that the SS protocol performs more accurately than the traditional NSS protocol and can be applied in future studies.

  7. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Fletcher, James C. (Inventor); Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1992-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  8. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1993-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of the additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  9. Protocols development for security and privacy of radio frequency identification systems

    NASA Astrophysics Data System (ADS)

    Sabbagha, Fatin

    There are benefits to adopting radio frequency identification (RFID) technology, although there are methods of attack that can compromise the system. This research determined how that may happen and what possible solutions can keep that from happening. Protocols were developed to implement better security. In addition, new topologies were developed to handle the problems of the key management. Previously proposed protocols focused on providing mutual authentication and privacy between readers and tags. However, those protocols are still vulnerable to be attacked. These protocols were analyzed and the disadvantages shown for each one. Previous works assumed that the channels between readers and the servers were secure. In the proposed protocols, a compromised reader is considered along with how to prevent tags from being read by that reader. The new protocols provide mutual authentication between readers and tags and, at the same time, remove the compromised reader from the system. Three protocols are proposed. In the first protocol, a mutual authentication is achieved and a compromised reader is not allowed in the network. In the second protocol, the number of times a reader contacts the server is reduced. The third protocol provides authentication and privacy between tags and readers using a trusted third party. The developed topology is implemented using python language and simulates work to check the efficiency regarding the processing time. The three protocols are implemented by writing codes in C language and then compiling them in MSP430. IAR Embedded workbench is used, which is an integrated development environment with the C/C++ compiler to generate a faster code and to debug the microcontroller. In summary, the goal of this research is to find solutions for the problems on previously proposed protocols, handle a compromised reader, and solve key management problems.

  10. Additional Types of Neuropathy

    MedlinePlus

    ... A A Listen En Español Additional Types of Neuropathy Charcot's Joint Charcot's Joint, also called neuropathic arthropathy, ... can stop bone destruction and aid healing. Cranial Neuropathy Cranial neuropathy affects the 12 pairs of nerves ...

  11. Food Additives and Hyperkinesis

    ERIC Educational Resources Information Center

    Wender, Ester H.

    1977-01-01

    The hypothesis that food additives are causally associated with hyperkinesis and learning disabilities in children is reviewed, and available data are summarized. Available from: American Medical Association 535 North Dearborn Street Chicago, Illinois 60610. (JG)

  12. Smog control fuel additives

    SciTech Connect

    Lundby, W.

    1993-06-29

    A method is described of controlling, reducing or eliminating, ozone and related smog resulting from photochemical reactions between ozone and automotive or industrial gases comprising the addition of iodine or compounds of iodine to hydrocarbon-base fuels prior to or during combustion in an amount of about 1 part iodine per 240 to 10,000,000 parts fuel, by weight, to be accomplished by: (a) the addition of these inhibitors during or after the refining or manufacturing process of liquid fuels; (b) the production of these inhibitors for addition into fuel tanks, such as automotive or industrial tanks; or (c) the addition of these inhibitors into combustion chambers of equipment utilizing solid fuels for the purpose of reducing ozone.

  13. A Unified Fault-Tolerance Protocol

    NASA Technical Reports Server (NTRS)

    Miner, Paul; Gedser, Alfons; Pike, Lee; Maddalon, Jeffrey

    2004-01-01

    Davies and Wakerly show that Byzantine fault tolerance can be achieved by a cascade of broadcasts and middle value select functions. We present an extension of the Davies and Wakerly protocol, the unified protocol, and its proof of correctness. We prove that it satisfies validity and agreement properties for communication of exact values. We then introduce bounded communication error into the model. Inexact communication is inherent for clock synchronization protocols. We prove that validity and agreement properties hold for inexact communication, and that exact communication is a special case. As a running example, we illustrate the unified protocol using the SPIDER family of fault-tolerant architectures. In particular we demonstrate that the SPIDER interactive consistency, distributed diagnosis, and clock synchronization protocols are instances of the unified protocol.

  14. [The research protocol. Part I].

    PubMed

    Miranda-Novales, María Guadalupe; Villasís-Keever, Miguel Ángel

    2015-01-01

    One of the principal aims in research is the publication of the study in scientific journals. This implies two challenges: the first one, the election of an adequate research design, and the second one, the concrete and simple wording of the results for the study to be accepted in the most appropriate journal according to the scope. Despite numerous supporting documents are available for both issues, the publication process is long, tiresome, and can discourage the most enthusiastic researcher. This is the first of a series of articles with the objective to describe the steps from the research question to the publication of the study. First of all, the importance of the research design will be addressed. The structure of the protocol is essential to achieve the objectives, and provides a way to organize the investigation in a logic, comprehensible and efficient manner.

  15. [Climate change and Kyoto protocol].

    PubMed

    Ergasti, G; Pippia, V; Murzilli, G; De Luca D'Alessandro, E

    2009-01-01

    Due to industrial revolution and the heavy use of fossil fuels, the concentration of greenhouse gases in the atmosphere has increased dramatically during the last hundred years, and this has lead to an increase in mean global temperature. The environmental consequences of this are: the melting of the ice caps, an increase in mean sea-levels, catastrophic events such as floodings, hurricanes and earthquakes, changes to the animal and vegetable kingdoms, a growth in vectors and bacteria in water thus increasing the risk of infectious diseases and damage to agriculture. The toxic effects of the pollution on human health are both acute and chronic. The Kyoto Protocol is an important step in the campaign against climatic changes but it is not sufficient. A possible solution might be for the States which produce the most of pollution to adopt a better political stance for the environment and to use renewable resources for the production of energy.

  16. Layered protocols in voice interaction with computers

    NASA Astrophysics Data System (ADS)

    Taylor, M. M.

    1987-02-01

    The Layered Protocol model for human computer interfaces is described, with special reference to the problems of voice input and output. In a layered protocol, each level passes virtual messages back and forth between human and computer. These virtual messages are realized in the form of interchanges at the level below. The protocol at a level is analogous to the syntax of a sentence, in that it is the method by which the content of a message can be given an agreed interpretation. Each protocol can be designed or evaluated independently of all the others in an interface. The stability of a protocol is determined by its response delays and by the channel capacity of the lower level protocols that support its messages. Sometimes an unstable protocol can be stabilized and speeded by reducing the message rate of the supporting protocols. Users have been observed to do this intuitively. Voice input provides special problems because of the relatively high error probability inherent in the recognizer: errors in other modalities are likely to be due to operator fault. This tends to lead to unwarranted distrust of voice input, and to demands for types of feedback that are probably inappropriate to the level of protocol to which the recognizer is suited. Voice output can be used by the computer to initiate protocols, or to provide a response channel for protocols under conditions where the user's eyes are otherwise occupied. Consideration of protocol demands helps to clarify the requirements for precision in recognition, and for the characteristics of computer responses to voice input; it helps also in judging appropriate conditions for the use of voice output.

  17. Status Report on the UNIDROIT Space Protocol

    NASA Astrophysics Data System (ADS)

    Larsen, Paul B.

    2002-01-01

    In my status report on the UNIDROIT Space Protocol I will describe the history and purpose of the Space Protocol; I will state the Protocol's relationship to the UNIDROIT Convention on International Interests in Mobile Equipment in particular after the 2001 Cape Town Diplomatic Conference on the Convention. I will describe the COPUOS study of possible conflicts with the existing space law treaties and explain UNIDROIT's objective of avoiding conflicts between existing space law and the Space Protocol. Finally I will describe future steps to be taken.

  18. Quantum three-pass cryptography protocol

    NASA Astrophysics Data System (ADS)

    Yang, Li; Wu, Ling-An; Liu, Songhao

    2002-09-01

    We present a new kind of quantum cryptography protocol based on Shamir's three-pass protocol of classical cryptography, which allows the transmission of qubits directly and secretly via the aid of an unjammable classical channel. In this protocol we implement the encryption and decryption transformations via rotations on the Poincare sphere of the photons polarization parameters. The key technique is that Bob's encryption rotation must be commutative with Alice s decryption rotation; this means that the axes of these two rotations must be parallel. We also present a security analysis of the protocol under a man-in-the-middle attack.

  19. Additive Manufacturing Infrared Inspection

    NASA Technical Reports Server (NTRS)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  20. Designing an Exploration Atmosphere Prebreathe Protocol

    NASA Technical Reports Server (NTRS)

    Conkin, Johnny; Feiveson, A. H.; Gernhardt, M. L.; Norcross, J. R.; Wessel, J. H., III

    2015-01-01

    Extravehicular activities (EVAs) at remote locations must maximize limited resources such as oxygen (O2) and also minimize the risk of decompression sickness (DCS). A proposed remote denitrogenation (prebreathe) protocol requires astronauts to live in a mildly hypoxic atmosphere at 8.2 psia while periodically performing EVAs at 4.3 psia. Empirical data are required to confirm that the protocol meets the current accept requirements: less than or equal to 15% incidence of Type I DCS, less than or equal to 20% incidence of Grade IV venous gas emboli (VGE), both at 95% statistical confidence, with no Type II DCS symptom during the validation trial. METHODS: A repeated measures statistical design is proposed in which groups of 6 subjects with physical characteristics similar to active-duty astronauts would first become equilibrated to an 8.2 psia atmosphere in a hypobaric chamber containing 34% O2 and 66% N2, over 48 h, and then perform 4 simulated EVAs at 4.3 psia over the next 9 days. In the equilibration phase, subjects undergo a 3-h 100% O2 mask prebreathe prior to and during a 5-min ascent to 8.2 psia to prevent significant tissue N2 supersaturation on reaching 8.2 psia. Masks would be removed once 34% O2 is established at 8.2 psia, and subjects would then equilibrate to this atmosphere for 48 h. The hypoxia is equivalent to breathing air at 1,220 meters (4,000 ft) altitude, just as was experienced in the shuttle 10.2 psia - 26.5% O2 staged denitrogenation protocol and the current ISS campout denitrogenation protocol. For simulated EVAs, each subject dons a mask and breathes 85% O2 and 15% N2 during a 3-min depressurization to 6.0 psia, holds for 15 min, and then completes a 3-min depressurization to 4.3 psia. The simulated EVA period starts when 6.0 psia is reached and continues for a total of 240 min (222 min at 4.3 psia). During this time, subjects will follow a prescribed repetitive activity against loads in the upper and lower body with mean metabolic rate

  1. Phenylethynyl Containing Reactive Additives

    NASA Technical Reports Server (NTRS)

    Connell, John W. (Inventor); Smith, Joseph G., Jr. (Inventor); Hergenrother, Paul M. (Inventor)

    2002-01-01

    Phenylethynyl containing reactive additives were prepared from aromatic diamine, containing phenylethvnvl groups and various ratios of phthalic anhydride and 4-phenylethynviphthalic anhydride in glacial acetic acid to form the imide in one step or in N-methyl-2-pvrrolidinone to form the amide acid intermediate. The reactive additives were mixed in various amounts (10% to 90%) with oligomers containing either terminal or pendent phenylethynyl groups (or both) to reduce the melt viscosity and thereby enhance processability. Upon thermal cure, the additives react and become chemically incorporated into the matrix and effect an increase in crosslink density relative to that of the host resin. This resultant increase in crosslink density has advantageous consequences on the cured resin properties such as higher glass transition temperature and higher modulus as compared to that of the host resin.

  2. Protocols for Image Processing based Underwater Inspection of Infrastructure Elements

    NASA Astrophysics Data System (ADS)

    O'Byrne, Michael; Ghosh, Bidisha; Schoefs, Franck; Pakrashi, Vikram

    2015-07-01

    Image processing can be an important tool for inspecting underwater infrastructure elements like bridge piers and pile wharves. Underwater inspection often relies on visual descriptions of divers who are not necessarily trained in specifics of structural degradation and the information may often be vague, prone to error or open to significant variation of interpretation. Underwater vehicles, on the other hand can be quite expensive to deal with for such inspections. Additionally, there is now significant encouragement globally towards the deployment of more offshore renewable wind turbines and wave devices and the requirement for underwater inspection can be expected to increase significantly in the coming years. While the merit of image processing based assessment of the condition of underwater structures is understood to a certain degree, there is no existing protocol on such image based methods. This paper discusses and describes an image processing protocol for underwater inspection of structures. A stereo imaging image processing method is considered in this regard and protocols are suggested for image storage, imaging, diving, and inspection. A combined underwater imaging protocol is finally presented which can be used for a variety of situations within a range of image scenes and environmental conditions affecting the imaging conditions. An example of detecting marine growth is presented of a structure in Cork Harbour, Ireland.

  3. Chapter 19: HVAC Controls (DDC/EMS/BAS) Evaluation Protocol

    SciTech Connect

    Romberger, J.

    2014-11-01

    The HVAC Controls Evaluation Protocol is designed to address evaluation issues for direct digital controls/energy management systems/building automation systems (DDC/EMS/BAS) that are installed to control heating, ventilation, and air-conditioning (HVAC) equipment in commercial and institutional buildings. (This chapter refers to the DDC/EMS/BAS measure as HVAC controls.) This protocol may also be applicable to industrial facilities such as clean rooms and labs, which have either significant HVAC equipment or spaces requiring special environmental conditions. This protocol addresses only HVAC-related equipment and the energy savings estimation methods associated with installing such control systems as an energy efficiency measure. The affected equipment includes: Air-side equipment (air handlers, direct expansion systems, furnaces, other heating- and cooling-related devices, terminal air distribution equipment, and fans); Central plant equipment (chillers, cooling towers, boilers, and pumps). These controls may also operate or affect other end uses, such as lighting, domestic hot water, irrigation systems, and life safety systems such as fire alarms and other security systems. Considerable nonenergy benefits, such as maintenance scheduling, system component troubleshooting, equipment failure alarms, and increased equipment lifetime, may also be associated with these systems. When connected to building utility meters, these systems can also be valuable demand-limiting control tools. However, this protocol does not evaluate any of these additional capabilities and benefits.

  4. Packet Drop Avoidance for High-speed network transmission protocol

    SciTech Connect

    Jin, Guojun

    2004-05-01

    As network bandwidth continues to grow and longer paths are used to exchange large scientific data between storage systems and GRID computation, it has become increasingly obvious that there is a need to deploy a packet drop avoidance mechanism into network transmission protocols. Current end-to-end congestion avoidance mechanisms used in Transmission Control Protocol (TCP) have worked well on low bandwidth delay product networks, but with newer high-bandwidth delay networks they have shown to be inefficient and prone to unstable. This is largely due to increased network bandwidth coupled with changes in internet traffic patterns. These changes come from a variety of new network applications that are being developed to take advantage of the increased network bandwidth. This paper will examine the end-to-end congestion avoidance mechanism and perform a step-by-step analysis of its theory. In addition we will propose an alternative approach developed as part of a new network transmission protocol. Our alternative protocol uses a packet drop avoidance (PDA) mechanism built on top of the maximum burst size (MBS) theory combined with a real-time available bandwidth algorithm.

  5. Rapid Ultrasound in Shock (RUSH) Velocity-Time Integral: A Proposal to Expand the RUSH Protocol.

    PubMed

    Blanco, Pablo; Aguiar, Francisco Miralles; Blaivas, Michael

    2015-09-01

    Ultrasound assessment of patients in shock is becoming the standard of care in emergency and critical care settings worldwide. One of the most common protocols used for this assessment is the rapid ultrasound in shock (RUSH) examination. The RUSH protocol is a rapid evaluation of cardiac function, key vascular structures, and likely sources of hypotension. Stroke volume is an established important value to assess in the setting of shock, allowing the provider to predict the patient's response to treatment. However, the calculation of stroke volume or its surrogates is not part of any protocol, including RUSH. We propose the addition of ultrasound calculation of stroke volume or surrogates to the RUSH protocol and provide support for its utility and relative ease of calculation. The resulting product would be the RUSH velocity-time integral protocol.

  6. Simulation and research on security enhancement policies of space network protocols

    NASA Astrophysics Data System (ADS)

    Ma, Hengtai; Hong, Zhiguo; Zhu, Dengke; Zheng, Gang

    2007-11-01

    In this paper, the state of the art of network protocols and security problems of space networks are firstly introduced. Then, it analyzes some security protocols that can be applicable to satellite networks. To validate the effect of security protocols in space networks, we use Stochastic Petri Nets (SPN) to model the communication process of Border Gateway Protocol - Satellite version (BGP-S). Furthermore, by comparison and analysis, the effect of three security protocols on average time delay is also analyzed from the SPN model with Stochastic Petri Net Package (SPNP) 6.0. What's more, the policies on choosing security shemes are discussed. Finally, a NS-2-based simulation for BGP-S is implemented and with the addition of security data flow test is made by comparison and analysis. Simulation results are basically in accordance with the numerical results of the SPN model.

  7. Rapid Ultrasound in Shock (RUSH) Velocity-Time Integral: A Proposal to Expand the RUSH Protocol.

    PubMed

    Blanco, Pablo; Aguiar, Francisco Miralles; Blaivas, Michael

    2015-09-01

    Ultrasound assessment of patients in shock is becoming the standard of care in emergency and critical care settings worldwide. One of the most common protocols used for this assessment is the rapid ultrasound in shock (RUSH) examination. The RUSH protocol is a rapid evaluation of cardiac function, key vascular structures, and likely sources of hypotension. Stroke volume is an established important value to assess in the setting of shock, allowing the provider to predict the patient's response to treatment. However, the calculation of stroke volume or its surrogates is not part of any protocol, including RUSH. We propose the addition of ultrasound calculation of stroke volume or surrogates to the RUSH protocol and provide support for its utility and relative ease of calculation. The resulting product would be the RUSH velocity-time integral protocol. PMID:26283755

  8. GENERIC VERIFICATION PROTOCOL: DISTRIBUTED GENERATION AND COMBINED HEAT AND POWER FIELD TESTING PROTOCOL

    EPA Science Inventory

    This report is a generic verification protocol by which EPA’s Environmental Technology Verification program tests newly developed equipment for distributed generation of electric power, usually micro-turbine generators and internal combustion engine generators. The protocol will ...

  9. EXACT2: the semantics of biomedical protocols

    PubMed Central

    2014-01-01

    Background The reliability and reproducibility of experimental procedures is a cornerstone of scientific practice. There is a pressing technological need for the better representation of biomedical protocols to enable other agents (human or machine) to better reproduce results. A framework that ensures that all information required for the replication of experimental protocols is essential to achieve reproducibility. Methods We have developed the ontology EXACT2 (EXperimental ACTions) that is designed to capture the full semantics of biomedical protocols required for their reproducibility. To construct EXACT2 we manually inspected hundreds of published and commercial biomedical protocols from several areas of biomedicine. After establishing a clear pattern for extracting the required information we utilized text-mining tools to translate the protocols into a machine amenable format. We have verified the utility of EXACT2 through the successful processing of previously 'unseen' (not used for the construction of EXACT2) protocols. Results The paper reports on a fundamentally new version EXACT2 that supports the semantically-defined representation of biomedical protocols. The ability of EXACT2 to capture the semantics of biomedical procedures was verified through a text mining use case. In this EXACT2 is used as a reference model for text mining tools to identify terms pertinent to experimental actions, and their properties, in biomedical protocols expressed in natural language. An EXACT2-based framework for the translation of biomedical protocols to a machine amenable format is proposed. Conclusions The EXACT2 ontology is sufficient to record, in a machine processable form, the essential information about biomedical protocols. EXACT2 defines explicit semantics of experimental actions, and can be used by various computer applications. It can serve as a reference model for for the translation of biomedical protocols in natural language into a semantically

  10. Multifunctional fuel additives

    SciTech Connect

    Baillargeon, D.J.; Cardis, A.B.; Heck, D.B.

    1991-03-26

    This paper discusses a composition comprising a major amount of a liquid hydrocarbyl fuel and a minor low-temperature flow properties improving amount of an additive product of the reaction of a suitable diol and product of a benzophenone tetracarboxylic dianhydride and a long-chain hydrocarbyl aminoalcohol.

  11. Biobased lubricant additives

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Fully biobased lubricants are those formulated using all biobased ingredients, i.e. biobased base oils and biobased additives. Such formulations provide the maximum environmental, safety, and economic benefits expected from a biobased product. Currently, there are a number of biobased base oils that...

  12. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Weapons (NPT). ITAR. The International Traffic in Arms Regulations (22 CFR Parts 120-130), which are... collection of environmental samples (e.g., air, water, vegetation, soil, smears) at, and in the...

  13. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... United States of America and the International Atomic Energy Agency for the Application of Safeguards in... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Commission (NRC) has entered into an effective agreement under Subsection 274b of the Atomic Energy Act...

  14. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... United States of America and the International Atomic Energy Agency for the Application of Safeguards in... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Commission (NRC) has entered into an effective agreement under Subsection 274b of the Atomic Energy Act...

  15. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... United States of America and the International Atomic Energy Agency for the Application of Safeguards in... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Commission (NRC) has entered into an effective agreement under Subsection 274b of the Atomic Energy Act...

  16. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... United States of America and the International Atomic Energy Agency for the Application of Safeguards in... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Commission (NRC) has entered into an effective agreement under Subsection 274b of the Atomic Energy Act...

  17. 21 CFR 1301.18 - Research protocols.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... to 21 U.S.C. 355(i) and 21 CFR 130.3, I, (Name and Address of IND Sponsor) submitted a Notice of... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A...

  18. STANDARD MEASUREMENT PROTOCOLS - FLORIDA RADON RESEARCH PROGRAM

    EPA Science Inventory

    The manual, in support of the Florida Radon Research Program, contains standard protocols for key measurements where data quality is vital to the program. t contains two sections. he first section, soil measurements, contains field sampling protocols for soil gas permeability and...

  19. Open commit protocols tolerating commission failures

    SciTech Connect

    Rothermel, K.; Pappe, S. )

    1993-06-01

    To ensure atomicity of transactions in disturbed systems so-called 2-phase commit (2PC) protocols have been proposed. The basic assumption of these protocols is that the processing nodes involved in transactions are [open quotes]sane,[close quotes] i.e., they only fail with omission failures, and nodes eventually recover from failures. Unfortunately, this assumption is not realistic for so-called Open Distributed Systems (ODSs), in which nodes may have totally different reliability characteristics. In ODSs, nodes can be classified into trusted nodes (e.g., a banking server) and nontrusted nodes (e.g., a home PC requesting a remote banking service). While trusted nodes are assumed to be sane, nontrusted nodes may fail permanently and even cause commission failures to occur. In this paper, we propose a family of 2PC protocols that tolerate any number of omission failures at trusted nodes and any number of commission and omission failures at nontrusted nodes. The proposed protocols ensure that (at least) the trusted nodes participating in a transaction eventually terminate the transaction in a consistent manner. Unlike Byzantine commit protocols, our protocols do not incorporate mechanisms for achieving Byzantine agreement, which has advantages in terms of complexity: Our protocols have the same or only a slightly higher message complexity than traditional 2PC protocols. 31 refs., 10 figs., 3 tabs.

  20. Communication protocol standards for space data systems

    NASA Technical Reports Server (NTRS)

    Hooke, Adrian J.; Desjardins, Richard

    1990-01-01

    The main elements and requirements of advanced space data networks are identified. The communication protocol standards for use on space missions during the coming decades are described. In particular, the blending of high-performance space-unique data transmission techniques with off-the-shelf open systems interconnection (OSI) protocols is described.

  1. 21 CFR 1301.18 - Research protocols.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Research protocols. 1301.18 Section 1301.18 Food... duration of the project. (v) Location where the research will be conducted. (vi) Statement of the security... security provisions (as proscribed in paragraph (a)(2)(vi) of this section for a research protocol) to,...

  2. 21 CFR 1301.18 - Research protocols.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Research protocols. 1301.18 Section 1301.18 Food... duration of the project. (v) Location where the research will be conducted. (vi) Statement of the security... security provisions (as proscribed in paragraph (a)(2)(vi) of this section for a research protocol) to,...

  3. Massive transfusion and massive transfusion protocol

    PubMed Central

    Patil, Vijaya; Shetmahajan, Madhavi

    2014-01-01

    Haemorrhage remains a major cause of potentially preventable deaths. Rapid transfusion of large volumes of blood products is required in patients with haemorrhagic shock which may lead to a unique set of complications. Recently, protocol based management of these patients using massive transfusion protocol have shown improved outcomes. This section discusses in detail both management and complications of massive blood transfusion. PMID:25535421

  4. 16 CFR 1212.4 - Test protocol.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Test protocol. 1212.4 Section 1212.4... STANDARD FOR MULTI-PURPOSE LIGHTERS Requirements for Child-Resistance § 1212.4 Test protocol. (a) Child test panel. (1) The test to determine if a multi-purpose lighter is resistant to successful...

  5. 16 CFR 1210.4 - Test protocol.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Test protocol. 1210.4 Section 1210.4... STANDARD FOR CIGARETTE LIGHTERS Requirements for Child Resistance § 1210.4 Test protocol. (a) Child test panel. (1) The test to determine if a lighter is resistant to successful operation by children uses...

  6. Massive transfusion and massive transfusion protocol.

    PubMed

    Patil, Vijaya; Shetmahajan, Madhavi

    2014-09-01

    Haemorrhage remains a major cause of potentially preventable deaths. Rapid transfusion of large volumes of blood products is required in patients with haemorrhagic shock which may lead to a unique set of complications. Recently, protocol based management of these patients using massive transfusion protocol have shown improved outcomes. This section discusses in detail both management and complications of massive blood transfusion.

  7. Comparison of different stimulation protocols used in in vitro fertilization: a review

    PubMed Central

    Shrestha, Deekshya; Feng, Huai L.

    2015-01-01

    Infertility is one of the major medical problems in the western world caused by genetic or epigenetic factors, or both, which has led to continuous research and advancements in the field of assisted reproductive technology (ART). Many stimulation protocols are available for controlled ovarian hyperstimulation (COH) in in vitro fertilization (IVF). This review compares the agonist long protocol, antagonist protocol and minimal stimulation protocol. Gonadotropin-releasing hormone (GnRH) antagonist and minimal stimulation protocol has shorter duration of treatment and less gonadotropin use. GnRH agonist long protocol is better in folliculogenesis and pregnancy rate, which is the imperative goal of COH. Despite its costly and lengthy approach, GnRH agonist long protocol has delivered satisfactory results in most women. On the other hand, patients with poor ovarian reserve may have greater advantage when considering minimal stimulation protocol. Evidently, it is crucial to have a larger scale studies with more focused comparisons, which take into account the differences in patients’ response criteria and additional confounding variables (age, BMI, previous IVF outcomes etc.), in order to reach to a more definite conclusions. PMID:26207230

  8. Comparison of a standard and a detailed postmortem protocol for detecting Mycobacterium bovis in badgers.

    PubMed

    Crawshaw, T R; Griffiths, I B; Clifton-Hadley, R S

    2008-10-18

    A standard postmortem protocol, consisting of gross pathology, culture for mycobacteria and limited selective histopathology, was used in the randomised badger culling trial in Great Britain to detect Mycobacterium bovis infection. This standard protocol was compared with a more detailed protocol in which more tissues were examined grossly, more tissues were cultured, more culture slopes were seeded, the culture period was extended and tissues were examined routinely by histopathology. The standard protocol was more sensitive in badgers with gross visible lesions than in badgers with no gross visible lesions. When applied to the study population of badgers, the overall sensitivity of the standard protocol relative to the more detailed protocol was estimated to be 54.6 per cent (95 per cent confidence interval 44.9 to 69.8 per cent). Badgers with tuberculosis (tb) detected by the standard protocol had a mean of 7.6 tissues with microscopic lesions suspicious of tb. The additional badgers detected by the detailed protocol had a mean of 4.4 tissues with microscopic lesions suspicious of tb.

  9. Online protocol annotation: a method to enhance undergraduate laboratory research skills.

    PubMed

    Ruble, Julie E; Lom, Barbara

    2008-01-01

    A well-constructed, step-by-step protocol is a critical starting point for teaching undergraduates new techniques, an important record of a lab's standard procedures, and a useful mechanism for sharing techniques between labs. Many research labs use websites to archive and share their protocols for these purposes. Here we describe our experiences developing and using a protocol website for the additional purpose of enhancing undergraduate research training. We created our lab's protocol website in a message board format that allows undergraduates to post comments on protocols describing the lessons they learned, questions that arose, and/or insights they gained while learning to execute specific research protocols. Encouraging and expecting students to comment on the protocols they are learning to execute is beneficial for both the student and for the lab in which they are training. For the student, annotations encourage active reflection on their execution of techniques and emphasize the important message that attending to and understanding details of a protocol is a critical factor in producing reliable data. For the lab, annotations capture valuable insights for future generations of researchers by describing missing details, hints, and common hurdles for newcomers.

  10. Vinyl capped addition polyimides

    NASA Technical Reports Server (NTRS)

    Vannucci, Raymond D. (Inventor); Malarik, Diane C. (Inventor); Delvigs, Peter (Inventor)

    1991-01-01

    Polyimide resins (PMR) are generally useful where high strength and temperature capabilities are required (at temperatures up to about 700 F). Polyimide resins are particularly useful in applications such as jet engine compressor components, for example, blades, vanes, air seals, air splitters, and engine casing parts. Aromatic vinyl capped addition polyimides are obtained by reacting a diamine, an ester of tetracarboxylic acid, and an aromatic vinyl compound. Low void materials with improved oxidative stability when exposed to 700 F air may be fabricated as fiber reinforced high molecular weight capped polyimide composites. The aromatic vinyl capped polyimides are provided with a more aromatic nature and are more thermally stable than highly aliphatic, norbornenyl-type end-capped polyimides employed in PMR resins. The substitution of aromatic vinyl end-caps for norbornenyl end-caps in addition polyimides results in polymers with improved oxidative stability.

  11. Tackifier for addition polyimides

    NASA Technical Reports Server (NTRS)

    Butler, J. M.; St.clair, T. L.

    1980-01-01

    A modification to the addition polyimide, LaRC-160, was prepared to improve tack and drape and increase prepeg out-time. The essentially solventless, high viscosity laminating resin is synthesized from low cost liquid monomers. The modified version takes advantage of a reactive, liquid plasticizer which is used in place of solvent and helps solve a major problem of maintaining good prepeg tack and drape, or the ability of the prepeg to adhere to adjacent plies and conform to a desired shape during the lay up process. This alternate solventless approach allows both longer life of the polymer prepeg and the processing of low void laminates. This approach appears to be applicable to all addition polyimide systems.

  12. Electrophilic addition of astatine

    SciTech Connect

    Norseev, Yu.V.; Vasaros, L.; Nhan, D.D.; Huan, N.K.

    1988-03-01

    It has been shown for the first time that astatine is capable of undergoing addition reactions to unsaturated hydrocarbons. A new compound of astatine, viz., ethylene astatohydrin, has been obtained, and its retention numbers of squalane, Apiezon, and tricresyl phosphate have been found. The influence of various factors on the formation of ethylene astatohydrin has been studied. It has been concluded on the basis of the results obtained that the univalent cations of astatine in an acidic medium is protonated hypoastatous acid.

  13. Cryptanalysis of the arbitrated quantum signature protocols

    SciTech Connect

    Gao Fei; Qin Sujuan; Guo Fenzhuo; Wen Qiaoyan

    2011-08-15

    As a new model for signing quantum messages, arbitrated quantum signature (AQS) has recently received a lot of attention. In this paper we study the cryptanalysis of previous AQS protocols from the aspects of forgery and disavowal. We show that in these protocols the receiver, Bob, can realize existential forgery of the sender's signature under known message attack. Bob can even achieve universal forgery when the protocols are used to sign a classical message. Furthermore, the sender, Alice, can successfully disavow any of her signatures by simple attack. The attack strategies are described in detail and some discussions about the potential improvements of the protocols are given. Finally we also present several interesting topics on AQS protocols that can be studied in future.

  14. Accuracy of NHANES periodontal examination protocols.

    PubMed

    Eke, P I; Thornton-Evans, G O; Wei, L; Borgnakke, W S; Dye, B A

    2010-11-01

    This study evaluates the accuracy of periodontitis prevalence determined by the National Health and Nutrition Examination Survey (NHANES) partial-mouth periodontal examination protocols. True periodontitis prevalence was determined in a new convenience sample of 454 adults ≥ 35 years old, by a full-mouth "gold standard" periodontal examination. This actual prevalence was compared with prevalence resulting from analysis of the data according to the protocols of NHANES III and NHANES 2001-2004, respectively. Both NHANES protocols substantially underestimated the prevalence of periodontitis by 50% or more, depending on the periodontitis case definition used, and thus performed below threshold levels for moderate-to-high levels of validity for surveillance. Adding measurements from lingual or interproximal sites to the NHANES 2001-2004 protocol did not improve the accuracy sufficiently to reach acceptable sensitivity thresholds. These findings suggest that NHANES protocols produce high levels of misclassification of periodontitis cases and thus have low validity for surveillance and research.

  15. Security Weaknesses in Arbitrated Quantum Signature Protocols

    NASA Astrophysics Data System (ADS)

    Liu, Feng; Zhang, Kejia; Cao, Tianqing

    2014-01-01

    Arbitrated quantum signature (AQS) is a cryptographic scenario in which the sender (signer), Alice, generates the signature of a message and then a receiver (verifier), Bob, can verify the signature with the help of a trusted arbitrator, Trent. In this paper, we point out there exist some security weaknesses in two AQS protocols. Our analysis shows Alice can successfully disavow any of her signatures by a simple attack in the first protocol. Furthermore, we study the security weaknesses of the second protocol from the aspects of forgery and disavowal. Some potential improvements of this kind of protocols are given. We also design a new method to authenticate a signature or a message, which makes AQS protocols immune to Alice's disavowal attack and Bob's forgery attack effectively.

  16. Cryptanalysis of the arbitrated quantum signature protocols

    NASA Astrophysics Data System (ADS)

    Gao, Fei; Qin, Su-Juan; Guo, Fen-Zhuo; Wen, Qiao-Yan

    2011-08-01

    As a new model for signing quantum messages, arbitrated quantum signature (AQS) has recently received a lot of attention. In this paper we study the cryptanalysis of previous AQS protocols from the aspects of forgery and disavowal. We show that in these protocols the receiver, Bob, can realize existential forgery of the sender's signature under known message attack. Bob can even achieve universal forgery when the protocols are used to sign a classical message. Furthermore, the sender, Alice, can successfully disavow any of her signatures by simple attack. The attack strategies are described in detail and some discussions about the potential improvements of the protocols are given. Finally we also present several interesting topics on AQS protocols that can be studied in future.

  17. The EXACT description of biomedical protocols

    PubMed Central

    Soldatova, Larisa N.; Aubrey, Wayne; King, Ross D.; Clare, Amanda

    2008-01-01

    Motivation: Many published manuscripts contain experiment protocols which are poorly described or deficient in information. This means that the published results are very hard or impossible to repeat. This problem is being made worse by the increasing complexity of high-throughput/automated methods. There is therefore a growing need to represent experiment protocols in an efficient and unambiguous way. Results: We have developed the Experiment ACTions (EXACT) ontology as the basis of a method of representing biological laboratory protocols. We provide example protocols that have been formalized using EXACT, and demonstrate the advantages and opportunities created by using this formalization. We argue that the use of EXACT will result in the publication of protocols with increased clarity and usefulness to the scientific community. Availability: The ontology, examples and code can be downloaded from http://www.aber.ac.uk/compsci/Research/bio/dss/EXACT/ Contact: Larisa Soldatova lss@aber.ac.uk PMID:18586727

  18. Functional Generalized Additive Models.

    PubMed

    McLean, Mathew W; Hooker, Giles; Staicu, Ana-Maria; Scheipl, Fabian; Ruppert, David

    2014-01-01

    We introduce the functional generalized additive model (FGAM), a novel regression model for association studies between a scalar response and a functional predictor. We model the link-transformed mean response as the integral with respect to t of F{X(t), t} where F(·,·) is an unknown regression function and X(t) is a functional covariate. Rather than having an additive model in a finite number of principal components as in Müller and Yao (2008), our model incorporates the functional predictor directly and thus our model can be viewed as the natural functional extension of generalized additive models. We estimate F(·,·) using tensor-product B-splines with roughness penalties. A pointwise quantile transformation of the functional predictor is also considered to ensure each tensor-product B-spline has observed data on its support. The methods are evaluated using simulated data and their predictive performance is compared with other competing scalar-on-function regression alternatives. We illustrate the usefulness of our approach through an application to brain tractography, where X(t) is a signal from diffusion tensor imaging at position, t, along a tract in the brain. In one example, the response is disease-status (case or control) and in a second example, it is the score on a cognitive test. R code for performing the simulations and fitting the FGAM can be found in supplemental materials available online.

  19. UNFINISHED BUSINESS: The Economics of The Kyoto Protocol

    SciTech Connect

    JA Edmonds; CN MacCracken; RD Sands; SH Kim

    2000-07-06

    The Kyoto Protocol to the Framework Convention on Climate Change (FCCC) was completed on the morning of December 11, 1997, following over two years of negotiations. The product of these deliberations is a complex and incomplete document knitting together the diversity of interests and perspectives represented by the more than 150 delegations. Because the document is complex, its implications are not immediately obvious. If it enters into force, the Kyoto Protocol will have far-reaching implications for all nations--both nations with obligations under the Protocol and those without obligations. National energy systems, and the world's energy system, could be forever changed. In this paper the authors develop an assessment of the energy and economic implications of achieving the goals of the Kyoto Protocol. They find that many of the details of the Protocol that remain to be worked out introduce critical uncertainties affecting the cost of compliance. There are also a variety of uncertainties that further complicate the analysis. These include future non-CO{sub 2} greenhouse gas emissions and the cost of their mitigation. Other uncertainties include the resolution of negotiations to establish rules for determining and allocating land-use emissions rights, mechanisms for Annex 1 trading, and participation by non-Annex 1 members in the Clean Development Mechanism. In addition, there are economic uncertainties, such as the behavior of Eastern Europe and the former Soviet Union in supplying emissions credits under Annex 1 trading. These uncertainties in turn could affect private sector investments in anticipation of the Protocol's entrance into force. The longer the nature of future obligations remains unclear, the less able decision makers will be to incorporate these rules into their investment decisions. They find that the cost of implementing the Protocol in the US can vary by more than an order of magnitude. The marginal cost could be as low as $26 per tonne of

  20. A polymerase chain reaction protocol for the detection of various geographical isolates of white spot virus.

    PubMed

    Tapay, L M; Nadala, E C; Loh, P C

    1999-09-01

    Polymerase chain reaction (PCR) primers were designed based on the sequence of a cloned fragment of the white spot virus (WSV) genome and were used to detect at least four geographic isolates of WSV from both experimentally- and naturally-infected shrimp. In addition to high specificity, the one-step and two-step PCR protocols were determined to have sensitivities of 10-100 pg and 100 femtograms respectively. The two-step PCR protocol is recommended as a very sensitive and specific alternative protocol to Western blot assay for the detection of WSV.

  1. A Simple XML Producer-Consumer Protocol

    NASA Technical Reports Server (NTRS)

    Smith, Warren; Gunter, Dan; Quesnel, Darcy; Biegel, Bryan (Technical Monitor)

    2001-01-01

    There are many different projects from government, academia, and industry that provide services for delivering events in distributed environments. The problem with these event services is that they are not general enough to support all uses and they speak different protocols so that they cannot interoperate. We require such interoperability when we, for example, wish to analyze the performance of an application in a distributed environment. Such an analysis might require performance information from the application, computer systems, networks, and scientific instruments. In this work we propose and evaluate a standard XML-based protocol for the transmission of events in distributed systems. One recent trend in government and academic research is the development and deployment of computational grids. Computational grids are large-scale distributed systems that typically consist of high-performance compute, storage, and networking resources. Examples of such computational grids are the DOE Science Grid, the NASA Information Power Grid (IPG), and the NSF Partnerships for Advanced Computing Infrastructure (PACIs). The major effort to deploy these grids is in the area of developing the software services to allow users to execute applications on these large and diverse sets of resources. These services include security, execution of remote applications, managing remote data, access to information about resources and services, and so on. There are several toolkits for providing these services such as Globus, Legion, and Condor. As part of these efforts to develop computational grids, the Global Grid Forum is working to standardize the protocols and APIs used by various grid services. This standardization will allow interoperability between the client and server software of the toolkits that are providing the grid services. The goal of the Performance Working Group of the Grid Forum is to standardize protocols and representations related to the storage and distribution of

  2. Exploring Shared Memory Protocols in FLASH

    SciTech Connect

    Horowitz, Mark; Kunz, Robert; Hall, Mary; Lucas, Robert; Chame, Jacqueline

    2007-04-01

    improvements of 18% on average using the non-coherent version. We also present data on the SpecOMP benchmarks, showing that the protocols have a modest overhead of less than 3% in applications where the alternative mechanisms are not needed. In addition to the selective coherence studies on the FLASH machine, in the last six months of this project ISI performed research on compiler technology for the transactional memory (TM) programming model being developed at Stanford. As part of this research ISI developed a compiler that recognizes transactional memory “pragmas” and automatically generates parallel code for the TM programming model

  3. H1 photonic crystal cavities for hybrid quantum information protocols.

    PubMed

    Hagemeier, Jenna; Bonato, Cristian; Truong, Tuan-Anh; Kim, Hyochul; Beirne, Gareth J; Bakker, Morten; van Exter, Martin P; Luo, Yunqiu; Petroff, Pierre; Bouwmeester, Dirk

    2012-10-22

    Hybrid quantum information protocols are based on local qubits, such as trapped atoms, NV centers, and quantum dots, coupled to photons. The coupling is achieved through optical cavities. Here we demonstrate far-field optimized H1 photonic crystal membrane cavities combined with an additional back reflection mirror below the membrane that meet the optical requirements for implementing hybrid quantum information protocols. Using numerical optimization we find that 80% of the light can be radiated within an objective numerical aperture of 0.8, and the coupling to a single-mode fiber can be as high as 92%. We experimentally prove the unique external mode matching properties by resonant reflection spectroscopy with a cavity mode visibility above 50%. PMID:23187235

  4. H1 photonic crystal cavities for hybrid quantum information protocols

    NASA Astrophysics Data System (ADS)

    Hagemeier, Jenna; Bonato, Cristian; Truong, Tuan-Anh; Kim, Hyochul; Beirne, Gareth J.; Bakker, Morten; van Exter, Martin P.; Luo, Yunqiu; Petroff, Pierre; Bouwmeester, Dirk

    2012-10-01

    Hybrid quantum information protocols are based on local qubits, such as trapped atoms, NV centers, and quantum dots, coupled to photons. The coupling is achieved through optical cavities. Here we demonstrate far-field optimized H1 photonic crystal membrane cavities combined with an additional back reflection mirror below the membrane that meet the optical requirements for implementing hybrid quantum information protocols. Using numerical optimization we find that 80% of the light can be radiated within an objective numerical aperture of 0.8, and the coupling to a single-mode fiber can be as high as 92%. We experimentally prove the unique external mode matching properties by resonant reflection spectroscopy with a cavity mode visibility above 50%.

  5. Some Protocols For Optical-Fiber Digital Communications

    NASA Technical Reports Server (NTRS)

    Yeh, Cavour; Gerla, Mario

    1989-01-01

    One works best in heavy traffic, another, in light traffic. Three protocols proposed for digital communications among stations connected by passive taps to pair of uni-directional optical-fiber buses. Mediate round-robin, bounded-delay access to buses by all stations and particularly suited to fast transmission. Partly because transmission medium passive (no relay stations) and partly because protocols distribute control of network among all stations with provision for addition and deletion of stations (no control stations), communication network able to resist and recover from failures. Implicit token propagates in one direction on one bus and in opposite direction on other bus, minimizing interval of silence between end of one round and beginning of next.

  6. STANDARD OPERATING PROTOCOLS FOR DECOMMISSIONING

    SciTech Connect

    Foss, D. L.; Stevens, J. L.; Gerdeman, F. W.

    2002-02-25

    Decommissioning projects at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites are conducted under project-specific decision documents, which involve extensive preparation time, public comment periods, and regulatory approvals. Often, the decision documents must be initiated at least one year before commencing the decommissioning project, and they are expensive and time consuming to prepare. The Rocky Flats Environmental Technology Site (RFETS) is a former nuclear weapons production plant at which hazardous substances and wastes were released or disposed during operations. As a result of the releases, RFETS was placed on the National Priorities List in 1989, and is conducting cleanup activities under a federal facilities compliance agreement. Working closely with interested stakeholders and state and federal regulatory agencies, RFETS has developed and implemented an improved process for obtaining the approvals. The key to streamlining the approval process has been the development of sitewide decision documents called Rocky Flats Cleanup Agreement Standard Operating Protocols or ''RSOPs.'' RSOPs have broad applicability, and could be used instead of project-specific documents. Although no two decommissioning projects are exactly the same and they may vary widely in contamination and other hazards, the basic steps taken for cleanup are usually similar. Because of this, using RSOPs is more efficient than preparing a separate project-specific decision documents for each cleanup action. Over the Rocky Flats cleanup life cycle, using RSOPs has the potential to: (1) Save over 5 million dollars and 6 months on the site closure schedule; (2) Eliminate preparing one hundred and twenty project-specific decision documents; and (3) Eliminate writing seventy-five closure description documents for hazardous waste unit closure and corrective actions.

  7. Investigation and Implementation of T-DMB Protocol in NCTUns Simulator

    NASA Astrophysics Data System (ADS)

    Zuyeva, Tatiana; Cabani, Adnane; Mouzna, Joseph

    Investigation of T-DMB protocol forced us to create simulation model. NCTUns simulator which is open source software and allows addition of new protocols was chosen for implementation. This is one of the first steps of research process. Here we would like to give small overview of T-DMB (DAB) system, describe proposed simulation model and problems which we have met during the work.

  8. Analysis on Imai-Shin's LR-AKE Protocol for Wireless Network Security

    NASA Astrophysics Data System (ADS)

    Wang, Yingjie; Luo, Wei; Shen, Changxiang

    In 2005 Imai and Shin proposed a leakage-resilient authenticated key exchange protocol(LR-AKE) for wireless network security. For simplicity, the protocol is based on password authentication plus additional secrets to fit wireless environment (e.g., computation constraint). In this paper we show that Imai-Shin’s scheme is vulnerable to both client and server impersonation attacks and needs to be improved to provide strong security for wireless network.

  9. New logistics protocols for distributed interactive simulation

    NASA Astrophysics Data System (ADS)

    Taylor, Darrin; Morrison, John; Katz, Warren; Felton, Erik; Herman, Deborah A.

    1995-06-01

    In today's environment, the transportation and maintenance of military forces is nearly as important as combat operations. Rapid deployment to regions of low-intensity conflict will become a very common training scenario for the U.S. military. Thus it is desirable to apply distributed simulation technology to train logistics personnel in their combat support roles. Currently, distributed interactive simulation (DIS) only contains rudimentary logistics protocols. This paper introduces new protocols designed to handle the logistics problem. The Newtonian protocol takes a physics-based approach to modeling interactions on the simulation network. This protocol consists of a family of protocol data units (PDUs) which are used to communicate forces in different circumstances. The protocol implements a small set of physical relations. This represents a flexible and general mechanism to describe battlefield interactions between network entities. The migratory object protocol (MOP) family addresses the transfer of control. General mechanisms provide the means to simulate resupply, repair, and maintenance of entities at any level of abstraction (individual soldier to division). It can also increase the fidelity of mine laying, enable handover of weapons for terminal guidance, allow for the distribution of aggregate-level simulation entities, provide capabilities for the simulation of personnel, etc.

  10. Snakebite management in Iran: Devising a protocol

    PubMed Central

    Monzavi, Seyed Mostafa; Dadpour, Bita; Afshari, Reza

    2014-01-01

    Background: Snakebite in Iran has been a health concern. However, management of snakebite is not standardized and varies from center to center. This study is aimed at devising an evidence-based comprehensive protocol for snakebite management in Iran, to reduce unnecessary variations in practice. Materials and Methods: A narrative search in electronic databases was performed. Fifty peer-reviewed articles, guidelines, and textbooks were reviewed and practical details were extracted. Our currently used protocol in the Mashhad Toxicology Center was supplemented with this information. Consequently an improved wide-range protocol was developed. The protocol was then discussed and amended within a focus group comprised of medical toxicologists and internal medicine specialists. The amended version was finally discussed with expert physicians specialized in different areas of medicine, to be optimized by supplementing other specific considerations. Results: During a one-year process, the protocol was finalized. The final version of the protocol, which was designed in six steps, comprised of three components: A schematic algorithm, a severity grading scale, and instructions for supportive and adjunctive treatments. The algorithm pertains to both Viperidae and Elapidae snakebite envenomations and consists of a planned course of action and dosing of antivenom, based on the severity of the envenomation. Conclusion: Snakebite envenomation is a clinical toxicologic emergency, which needs to be treated in a timely and organized manner. Hence, a multi-aspect protocol was designed to improve the clinical outcomes, reduce unnecessary administration of antivenom, and help physicians make more proper clinical judgments. PMID:24778670

  11. Performance Boosting Additive

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Mainstream Engineering Corporation was awarded Phase I and Phase II contracts from Goddard Space Flight Center's Small Business Innovation Research (SBIR) program in early 1990. With support from the SBIR program, Mainstream Engineering Corporation has developed a unique low cost additive, QwikBoost (TM), that increases the performance of air conditioners, heat pumps, refrigerators, and freezers. Because of the energy and environmental benefits of QwikBoost, Mainstream received the Tibbetts Award at a White House Ceremony on October 16, 1997. QwikBoost was introduced at the 1998 International Air Conditioning, Heating, and Refrigeration Exposition. QwikBoost is packaged in a handy 3-ounce can (pressurized with R-134a) and will be available for automotive air conditioning systems in summer 1998.

  12. Sewage sludge additive

    NASA Technical Reports Server (NTRS)

    Kalvinskas, J. J.; Mueller, W. A.; Ingham, J. D. (Inventor)

    1980-01-01

    The additive is for a raw sewage treatment process of the type where settling tanks are used for the purpose of permitting the suspended matter in the raw sewage to be settled as well as to permit adsorption of the dissolved contaminants in the water of the sewage. The sludge, which settles down to the bottom of the settling tank is extracted, pyrolyzed and activated to form activated carbon and ash which is mixed with the sewage prior to its introduction into the settling tank. The sludge does not provide all of the activated carbon and ash required for adequate treatment of the raw sewage. It is necessary to add carbon to the process and instead of expensive commercial carbon, coal is used to provide the carbon supplement.

  13. Perspectives on Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  14. Sarks as additional fermions

    NASA Astrophysics Data System (ADS)

    Agrawal, Jyoti; Frampton, Paul H.; Jack Ng, Y.; Nishino, Hitoshi; Yasuda, Osamu

    1991-03-01

    An extension of the standard model is proposed. The gauge group is SU(2) X ⊗ SU(3) C ⊗ SU(2) S ⊗ U(1) Q, where all gauge symmetries are unbroken. The colour and electric charge are combined with SU(2) S which becomes strongly coupled at approximately 500 GeV and binds preons to form fermionic and vector bound states. The usual quarks and leptons are singlets under SU(2) X but additional fermions, called sarks. transform under it and the electroweak group. The present model explains why no more than three light quark-lepton families can exist. Neutral sark baryons, called narks, are candidates for the cosmological dark matter having the characteristics designed for WIMPS. Further phenomenological implications of sarks are analyzed i including electron-positron annihilation. Z 0 decay, flavor-changing neutral currents. baryon-number non-conservation, sarkonium and the neutron electric dipole moment.

  15. Quantum key distribution protocol using random bases

    NASA Astrophysics Data System (ADS)

    Meslouhi, A.; Amellal, H.; Hassouni, Y.; El Baz, M.; El Allati, A.

    2016-04-01

    In order to enhance the quantum key distribution (QKD) security, a new protocol, “QKDPRB” based on random bases is proposed. It consists of using standard encoding bases moving circularly with a variable rotational angle α which depends on angular velocity ω(t); thus, the traditional bases turn into relative ones. To prove the security and the efficiency of the protocol, we present a universal demonstration which proves a high level security of the proposed protocol, even in the presence of the intercept and resend attack. Finally, the QKDPRB may improve the security of QKD.

  16. Performance evaluation of TCP over ABT protocols

    NASA Astrophysics Data System (ADS)

    Ata, Shingo; Murata, Masayuki; Miyahara, Hideo

    1998-10-01

    ABT is promising for effectively transferring a highly bursty data traffic in ATM networks. Most of past studies focused on the data transfer capability of ABT within the ATM layer. In actual, however, we need to consider the upper layer transport protocol since the transport layer protocol also supports a network congestion control mechanism. One such example is TCP, which is now widely used in the Internet. In this paper, we evaluate the performance of TCP over ABT protocols. Simulation results show that the retransmission mechanism of ABT can effectively overlay the TCP congestion control mechanism so that TCP operates in a stable fashion and works well only as an error recovery mechanism.

  17. Tandem bis-aza-Michael addition reaction of amines in aqueous medium promoted by polystyrenesulfonic Acid

    EPA Science Inventory

    An efficient and environmentally benign tandem bis-aza-Michael addition of amines catalyzed by polystyrene sulfonic acid (PSSA) is described. This operationally simple high yielding microwave assisted synthetic protocol proceeded in water in the absence of any organic solvent.

  18. Additive lattice kirigami

    PubMed Central

    Castle, Toen; Sussman, Daniel M.; Tanis, Michael; Kamien, Randall D.

    2016-01-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes. PMID:27679822

  19. Additive lattice kirigami

    PubMed Central

    Castle, Toen; Sussman, Daniel M.; Tanis, Michael; Kamien, Randall D.

    2016-01-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes.

  20. Protocol dependence of the jamming transition

    NASA Astrophysics Data System (ADS)

    Bertrand, Thibault; Behringer, Robert P.; Chakraborty, Bulbul; O'Hern, Corey S.; Shattuck, Mark D.

    2016-01-01

    We propose a theoretical framework for predicting the protocol dependence of the jamming transition for frictionless spherical particles that interact via repulsive contact forces. We study isostatic jammed disk packings obtained via two protocols: isotropic compression and simple shear. We show that for frictionless systems, all jammed packings can be obtained via either protocol. However, the probability to obtain a particular jammed packing depends on the packing-generation protocol. We predict the average shear strain required to jam initially unjammed isotropically compressed packings from the density of jammed packings, shape of their basins of attraction, and path traversed in configuration space. We compare our predictions to simulations of shear strain-induced jamming and find quantitative agreement. We also show that the packing fraction range, over which shear strain-induced jamming occurs, tends to zero in the large system limit for frictionless packings with overdamped dynamics.

  1. Authentication Protocol using Quantum Superposition States

    SciTech Connect

    Kanamori, Yoshito; Yoo, Seong-Moo; Gregory, Don A.; Sheldon, Frederick T

    2009-01-01

    When it became known that quantum computers could break the RSA (named for its creators - Rivest, Shamir, and Adleman) encryption algorithm within a polynomial-time, quantum cryptography began to be actively studied. Other classical cryptographic algorithms are only secure when malicious users do not have sufficient computational power to break security within a practical amount of time. Recently, many quantum authentication protocols sharing quantum entangled particles between communicators have been proposed, providing unconditional security. An issue caused by sharing quantum entangled particles is that it may not be simple to apply these protocols to authenticate a specific user in a group of many users. An authentication protocol using quantum superposition states instead of quantum entangled particles is proposed. The random number shared between a sender and a receiver can be used for classical encryption after the authentication has succeeded. The proposed protocol can be implemented with the current technologies we introduce in this paper.

  2. Protocol to Exploit Waiting Resources for UASNs.

    PubMed

    Hung, Li-Ling; Luo, Yung-Jeng

    2016-01-01

    The transmission speed of acoustic waves in water is much slower than that of radio waves in terrestrial wireless sensor networks. Thus, the propagation delay in underwater acoustic sensor networks (UASN) is much greater. Longer propagation delay leads to complicated communication and collision problems. To solve collision problems, some studies have proposed waiting mechanisms; however, long waiting mechanisms result in low bandwidth utilization. To improve throughput, this study proposes a slotted medium access control protocol to enhance bandwidth utilization in UASNs. The proposed mechanism increases communication by exploiting temporal and spatial resources that are typically idle in order to protect communication against interference. By reducing wait time, network performance and energy consumption can be improved. A performance evaluation demonstrates that when the data packets are large or sensor deployment is dense, the energy consumption of proposed protocol is less than that of existing protocols as well as the throughput is higher than that of existing protocols.

  3. NREL Test-to-Failure Protocol (Presentation)

    SciTech Connect

    Hacke, P.

    2012-03-01

    The presentation describes the test-to-failure protocol that was developed and piloted at NREL, stressing PV modules with multiple applications of damp heat (with bias) and thermal cycling until they fail.

  4. Protocol to Exploit Waiting Resources for UASNs.

    PubMed

    Hung, Li-Ling; Luo, Yung-Jeng

    2016-01-01

    The transmission speed of acoustic waves in water is much slower than that of radio waves in terrestrial wireless sensor networks. Thus, the propagation delay in underwater acoustic sensor networks (UASN) is much greater. Longer propagation delay leads to complicated communication and collision problems. To solve collision problems, some studies have proposed waiting mechanisms; however, long waiting mechanisms result in low bandwidth utilization. To improve throughput, this study proposes a slotted medium access control protocol to enhance bandwidth utilization in UASNs. The proposed mechanism increases communication by exploiting temporal and spatial resources that are typically idle in order to protect communication against interference. By reducing wait time, network performance and energy consumption can be improved. A performance evaluation demonstrates that when the data packets are large or sensor deployment is dense, the energy consumption of proposed protocol is less than that of existing protocols as well as the throughput is higher than that of existing protocols. PMID:27005624

  5. Oncotherapy: A System for Requesting Chemotherapy Protocols.

    PubMed

    Righi, Laura Vera

    2015-01-01

    A clinical decision support system is able to provide oncologists with suitable treatment options at the moment of decision making regarding which chemotherapy protocol is the best to apply to a particular oncological case. The National Cancer Institute has created a Guidelines Committee that establishes therapeutical options for each clinical case. The Health Informatics Department has developed Oncotherapy, a knowledge database that incorporates information provided by the Guidelines Committee. Oncotherapy includes a tailored information repository to provide oncologists in the public health system with the chemotherapy protocols available given three types of data: clinical diagnosis, clinical stage and therapy criteria. The protocol selected by the treating oncologist is sent back to Oncotherapy, which may create new knowledge that can be incorporated into the knowledge database. In this way, the system supports making the best decision according to the chemotherapy protocol options available. Furthermore, it can warn of errors that could result from mistakenly chosen therapies. PMID:26262420

  6. 21 CFR 58.120 - Protocol.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., body weight range, sex, source of supply, species, strain, substrain, and age of the test system. (5... methods to be used. (b) All changes in or revisions of an approved protocol and the reasons...

  7. Evolution of Natural Attenuation Evaluation Protocols

    EPA Science Inventory

    Traditionally the evaluation of the efficacy of natural attenuation was based on changes in contaminant concentrations and mass reduction. Statistical tools and models such as Bioscreen provided evaluation protocols which now are being approached via other vehicles including m...

  8. A practical quantum bit commitment protocol

    NASA Astrophysics Data System (ADS)

    Arash Sheikholeslam, S.; Aaron Gulliver, T.

    2012-01-01

    In this paper, we introduce a new quantum bit commitment protocol which is secure against entanglement attacks. A general cheating strategy is examined and shown to be practically ineffective against the proposed approach.

  9. Putting the Human Back in the Protocol

    NASA Astrophysics Data System (ADS)

    Christianson, Bruce

    Hello, everyone, and welcome to the 14th International Security Protocols Workshop. I’m going to start with a quotation from someone who, at least in principle, is in charge of a very different security community than ours:

  10. A Look Back at the Montreal Protocol

    NASA Video Gallery

    The Montreal Protocol is an international treaty designed to protect the ozone layer. This video takes a look back at how scientists, industry leaders, and policy makers came together to regulate C...

  11. Protocol dependence of the jamming transition.

    PubMed

    Bertrand, Thibault; Behringer, Robert P; Chakraborty, Bulbul; O'Hern, Corey S; Shattuck, Mark D

    2016-01-01

    We propose a theoretical framework for predicting the protocol dependence of the jamming transition for frictionless spherical particles that interact via repulsive contact forces. We study isostatic jammed disk packings obtained via two protocols: isotropic compression and simple shear. We show that for frictionless systems, all jammed packings can be obtained via either protocol. However, the probability to obtain a particular jammed packing depends on the packing-generation protocol. We predict the average shear strain required to jam initially unjammed isotropically compressed packings from the density of jammed packings, shape of their basins of attraction, and path traversed in configuration space. We compare our predictions to simulations of shear strain-induced jamming and find quantitative agreement. We also show that the packing fraction range, over which shear strain-induced jamming occurs, tends to zero in the large system limit for frictionless packings with overdamped dynamics. PMID:26871137

  12. Intermolecular Atom Transfer Radical Addition to Olefins Mediated by Oxidative Quenching of Photoredox Catalysts

    PubMed Central

    Nguyen, John D.; Tucker, Joseph W.; Konieczynska, Marlena D.; Stephenson, Corey R. J.

    2011-01-01

    Atom transfer radical addition of haloalkanes and α-halocarbonyls to olefins is efficiently performed with the photocatalyst Ir[(dF(CF3)ppy)2(dtbbpy)]PF6. This protocol is characterized by excellent yields, mild conditions, low catalyst loading, and broad scope. In addition, the atom transfer protocol can be used to quickly and efficiently introduce vinyl trifluoromethyl groups to olefins and access 1,1-cyclopropane diesters. PMID:21381734

  13. Protocol Development | Division of Cancer Prevention

    Cancer.gov

    The chemoprevention Phase I and II consortia must submit Letters of Intent for review and approval prior to the submission and review of the protocol. Letter of Intent (LOI) Process The chemoprevention Phase I and II consortia must submit Letters of Intent for review and approval prior to the submission and review of the protocol. DCP will solicit Letters of Intent from investigators who want to conduct clinical trials with specific agents. |

  14. Field Monitoring Protocol: Heat Pump Water Heaters

    SciTech Connect

    Sparn, B.; Earle, L.; Christensen, D.; Maguire, J.; Wilson, E.; Hancock, E.

    2013-02-01

    This document provides a standard field monitoring protocol for evaluating the installed performance of Heat Pump Water Heaters in residential buildings. The report is organized to be consistent with the chronology of field test planning and execution. Research questions are identified first, followed by a discussion of analysis methods, and then the details of measuring the required information are laid out. A field validation of the protocol at a house near the NREL campus is included for reference.

  15. Protocol for communications in potentially noisy environments

    DOEpatents

    Boyd, Gerlad M.; Farrow, Jeffrey

    2016-02-09

    A communications protocol that is designed for transmission of data in networks that are subjected to harsh conditions is described herein. A network includes a plurality of devices, where the devices comprise respective nodes. The nodes are in communication with one another by way of a central network hub. The protocol causes the nodes to transmit data over a network bus at different data rates depending upon whether the nodes are operating normally or an arbitration procedure has been invoked.

  16. Field Monitoring Protocol. Heat Pump Water Heaters

    SciTech Connect

    Sparn, B.; Earle, L.; Christensen, D.; Maguire, J.; Wilson, E.; Hancock, C. E.

    2013-02-01

    This document provides a standard field monitoring protocol for evaluating the installed performance of Heat Pump Water Heaters in residential buildings. The report is organized to be consistent with the chronology of field test planning and execution. Research questions are identified first, followed by a discussion of analysis methods, and then the details of measuring the required information are laid out. A field validation of the protocol at a house near the NREL campus is included for reference.

  17. A verification system of RMAP protocol controller

    NASA Astrophysics Data System (ADS)

    Khanov, V. Kh; Shakhmatov, A. V.; Chekmarev, S. A.

    2015-01-01

    The functional verification problem of IP blocks of RMAP protocol controller is considered. The application of the verification method using fully- functional models of the processor and the internal bus of a system-on-chip is justified. Principles of construction of a verification system based on the given approach are proposed. The practical results of creating a system of verification of IP block of RMAP protocol controller is presented.

  18. The impacts of electricity dispatch protocols on the emission reductions due to wind power and carbon tax.

    PubMed

    Yu, Yang; Rajagopal, Ram

    2015-02-17

    Two dispatch protocols have been adopted by electricity markets to deal with the uncertainty of wind power but the effects of the selection between the dispatch protocols have not been comprehensively analyzed. We establish a framework to compare the impacts of adopting different dispatch protocols on the efficacy of using wind power and implementing a carbon tax to reduce emissions. We suggest that a market has high potential to achieve greater emission reduction by adopting the stochastic dispatch protocol instead of the static protocol when the wind energy in the market is highly uncertain or the market has enough adjustable generators, such as gas-fired combustion generators. Furthermore, the carbon-tax policy is more cost-efficient for reducing CO2 emission when the market operates according to the stochastic protocol rather than the static protocol. An empirical study, which is calibrated according to the data from the Electric Reliability Council of Texas market, confirms that using wind energy in the Texas market results in a 12% CO2 emission reduction when the market uses the stochastic dispatch protocol instead of the 8% emission reduction associated with the static protocol. In addition, if a 6$/ton carbon tax is implemented in the Texas market operated according to the stochastic protocol, the CO2 emission is similar to the emission level from the same market with a 16$/ton carbon tax operated according to the static protocol. Correspondingly, the 16$/ton carbon tax associated with the static protocol costs 42.6% more than the 6$/ton carbon tax associated with the stochastic protocol. PMID:25607824

  19. The impacts of electricity dispatch protocols on the emission reductions due to wind power and carbon tax.

    PubMed

    Yu, Yang; Rajagopal, Ram

    2015-02-17

    Two dispatch protocols have been adopted by electricity markets to deal with the uncertainty of wind power but the effects of the selection between the dispatch protocols have not been comprehensively analyzed. We establish a framework to compare the impacts of adopting different dispatch protocols on the efficacy of using wind power and implementing a carbon tax to reduce emissions. We suggest that a market has high potential to achieve greater emission reduction by adopting the stochastic dispatch protocol instead of the static protocol when the wind energy in the market is highly uncertain or the market has enough adjustable generators, such as gas-fired combustion generators. Furthermore, the carbon-tax policy is more cost-efficient for reducing CO2 emission when the market operates according to the stochastic protocol rather than the static protocol. An empirical study, which is calibrated according to the data from the Electric Reliability Council of Texas market, confirms that using wind energy in the Texas market results in a 12% CO2 emission reduction when the market uses the stochastic dispatch protocol instead of the 8% emission reduction associated with the static protocol. In addition, if a 6$/ton carbon tax is implemented in the Texas market operated according to the stochastic protocol, the CO2 emission is similar to the emission level from the same market with a 16$/ton carbon tax operated according to the static protocol. Correspondingly, the 16$/ton carbon tax associated with the static protocol costs 42.6% more than the 6$/ton carbon tax associated with the stochastic protocol.

  20. The Variable Rate Intravenous Insulin Infusion Protocol.

    PubMed

    Collard, Benjamin; Sturgeon, Jonathan; Patel, Natasha; Asharia, Shabbar

    2014-01-01

    Insulin use among inpatients is high and associated with severe and regular medication errors. An initial baseline audit showed a wide variation in the prescription of intravenous insulin within the trust. These included variation in the choice of fluid prescribed, electrolyte levels not consistently checked, handwritten illegible prescriptions, and varying parameters set for adjustment of the prescription. A Variable Rate Intravenous Insulin Infusion protocol (VRIII)) was introduced to standardize intravenous insulin prescription throughout the trust by all members of the clinical team. We looked at and measured uptake and effects of the VRIII protocol in improving standardization of insulin prescription for inpatients on insulin at St George's NHS trust. The protocol was uploaded to the intranet to allow access 24 hours a day and the staff educated about it. The VRIII protocol was routinely used successfully throughout the trust. Any initial problems were addressed through education of clinical staff. The protocol has shown decreased prescribing and administrative errors, whilst demonstrating good glucose and electrolyte control. Use of a standardized protocol helps reduce medication errors and demonstrates good glycaemic control. Regular and continued education of clinical staff is necessary to maintain its efficacy. PMID:26734228

  1. Security enhanced user authentication protocol for wireless sensor networks using elliptic curves cryptography.

    PubMed

    Choi, Younsung; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Nam, Junghyun; Won, Dongho

    2014-06-10

    Wireless sensor networks (WSNs) consist of sensors, gateways and users. Sensors are widely distributed to monitor various conditions, such as temperature, sound, speed and pressure but they have limited computational ability and energy. To reduce the resource use of sensors and enhance the security of WSNs, various user authentication protocols have been proposed. In 2011, Yeh et al. first proposed a user authentication protocol based on elliptic curve cryptography (ECC) for WSNs. However, it turned out that Yeh et al.'s protocol does not provide mutual authentication, perfect forward secrecy, and key agreement between the user and sensor. Later in 2013, Shi et al. proposed a new user authentication protocol that improves both security and efficiency of Yeh et al.'s protocol. However, Shi et al.'s improvement introduces other security weaknesses. In this paper, we show that Shi et al.'s improved protocol is vulnerable to session key attack, stolen smart card attack, and sensor energy exhausting attack. In addition, we propose a new, security-enhanced user authentication protocol using ECC for WSNs.

  2. A Neural Networks-Based Hybrid Routing Protocol for Wireless Mesh Networks

    PubMed Central

    Kojić, Nenad; Reljin, Irini; Reljin, Branimir

    2012-01-01

    The networking infrastructure of wireless mesh networks (WMNs) is decentralized and relatively simple, but they can display reliable functioning performance while having good redundancy. WMNs provide Internet access for fixed and mobile wireless devices. Both in urban and rural areas they provide users with high-bandwidth networks over a specific coverage area. The main problems affecting these networks are changes in network topology and link quality. In order to provide regular functioning, the routing protocol has the main influence in WMN implementations. In this paper we suggest a new routing protocol for WMN, based on good results of a proactive and reactive routing protocol, and for that reason it can be classified as a hybrid routing protocol. The proposed solution should avoid flooding and creating the new routing metric. We suggest the use of artificial logic—i.e., neural networks (NNs). This protocol is based on mobile agent technologies controlled by a Hopfield neural network. In addition to this, our new routing metric is based on multicriteria optimization in order to minimize delay and blocking probability (rejected packets or their retransmission). The routing protocol observes real network parameters and real network environments. As a result of artificial logic intelligence, the proposed routing protocol should maximize usage of network resources and optimize network performance. PMID:22969360

  3. Security enhanced user authentication protocol for wireless sensor networks using elliptic curves cryptography.

    PubMed

    Choi, Younsung; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Nam, Junghyun; Won, Dongho

    2014-01-01

    Wireless sensor networks (WSNs) consist of sensors, gateways and users. Sensors are widely distributed to monitor various conditions, such as temperature, sound, speed and pressure but they have limited computational ability and energy. To reduce the resource use of sensors and enhance the security of WSNs, various user authentication protocols have been proposed. In 2011, Yeh et al. first proposed a user authentication protocol based on elliptic curve cryptography (ECC) for WSNs. However, it turned out that Yeh et al.'s protocol does not provide mutual authentication, perfect forward secrecy, and key agreement between the user and sensor. Later in 2013, Shi et al. proposed a new user authentication protocol that improves both security and efficiency of Yeh et al.'s protocol. However, Shi et al.'s improvement introduces other security weaknesses. In this paper, we show that Shi et al.'s improved protocol is vulnerable to session key attack, stolen smart card attack, and sensor energy exhausting attack. In addition, we propose a new, security-enhanced user authentication protocol using ECC for WSNs. PMID:24919012

  4. Security Enhanced User Authentication Protocol for Wireless Sensor Networks Using Elliptic Curves Cryptography

    PubMed Central

    Choi, Younsung; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Nam, Junghyun; Won, Dongho

    2014-01-01

    Wireless sensor networks (WSNs) consist of sensors, gateways and users. Sensors are widely distributed to monitor various conditions, such as temperature, sound, speed and pressure but they have limited computational ability and energy. To reduce the resource use of sensors and enhance the security of WSNs, various user authentication protocols have been proposed. In 2011, Yeh et al. first proposed a user authentication protocol based on elliptic curve cryptography (ECC) for WSNs. However, it turned out that Yeh et al.'s protocol does not provide mutual authentication, perfect forward secrecy, and key agreement between the user and sensor. Later in 2013, Shi et al. proposed a new user authentication protocol that improves both security and efficiency of Yeh et al.'s protocol. However, Shi et al.'s improvement introduces other security weaknesses. In this paper, we show that Shi et al.'s improved protocol is vulnerable to session key attack, stolen smart card attack, and sensor energy exhausting attack. In addition, we propose a new, security-enhanced user authentication protocol using ECC for WSNs. PMID:24919012

  5. A neural networks-based hybrid routing protocol for wireless mesh networks.

    PubMed

    Kojić, Nenad; Reljin, Irini; Reljin, Branimir

    2012-01-01

    The networking infrastructure of wireless mesh networks (WMNs) is decentralized and relatively simple, but they can display reliable functioning performance while having good redundancy. WMNs provide Internet access for fixed and mobile wireless devices. Both in urban and rural areas they provide users with high-bandwidth networks over a specific coverage area. The main problems affecting these networks are changes in network topology and link quality. In order to provide regular functioning, the routing protocol has the main influence in WMN implementations. In this paper we suggest a new routing protocol for WMN, based on good results of a proactive and reactive routing protocol, and for that reason it can be classified as a hybrid routing protocol. The proposed solution should avoid flooding and creating the new routing metric. We suggest the use of artificial logic-i.e., neural networks (NNs). This protocol is based on mobile agent technologies controlled by a Hopfield neural network. In addition to this, our new routing metric is based on multicriteria optimization in order to minimize delay and blocking probability (rejected packets or their retransmission). The routing protocol observes real network parameters and real network environments. As a result of artificial logic intelligence, the proposed routing protocol should maximize usage of network resources and optimize network performance. PMID:22969360

  6. Proposed testing protocols for commercial kitchen ventilation research

    SciTech Connect

    Parikh, J.S. )

    1991-03-01

    Commercial kitchen ventilation systems significantly impact energy use and peak energy demand in foodservice establishments. However, the amount of ventilation exhaust required by different building codes and standards varies widely. Moreover, there is no industry-wide accepted testing procedure that quantifies and verifies exhaust capture and addresses the various types of cooking equipment used in commercial kitchens. This report provides a review of some requirements and practices which are currently in use. Proposals aimed at developing a more uniform approach to ventilation are discussed, including proposals for cooking and ventilation test protocols. Information obtained through a literature search and solicitation of information from cooking appliance and ventilation equipment manufacturers supports the conclusion that additional research and testing is needed to develop methods to establish ventilation requirements of commercial cooking equipment. Based on information gathered, and a meeting with industry representatives, draft test protocols were developed. The proposed protocols call for separate testing of cooking equipment and exhaust hoods. Tests of cooking equipment would be intended to characterize the effluent produced by specific equipment and cooking processes, and to facilitate equipment categorization with respect to cooking surface temperature and effluent generation rates. Using this information on cooking equipment, ventilation hoods would be tested to develop test procedures to determine ventilation requirements for specific hood and cooking equipment combinations. 12 refs., 7 tabs.

  7. Simple Line Access Protocol Version 1.0

    NASA Astrophysics Data System (ADS)

    Osuna, Pedro; Salgado, Jesus; Guainazzi, Matteo; Barbarisi, Isa; Dubernet, Marie-Lise; Tody, Doug; Osuna, Pedro; Salgado, Jesus

    2010-12-01

    The Simple Line Access Protocol (SLAP) is an IVOA Data Access protocol which defines a protocol for retrieving spectral lines coming from various Spectral Line Data Collections through a uniform interface within the VO framework. These lines can be either observed or theoretical and will be typically used to identify emission or absorption features in astronomical spectra. It makes use of the Simple Spectral Line Data Model (SSLDM [1]) to characterize spectral lines through the use of uTypes [14]. Physical quantities of units are described by using the standard Units DM [15]. SLAP services can be registered in an IVOA Registry of Resources using the VOResource [12] Extension standard, having a unique ResourceIdentifier [13] in the Registry. The SLAP interface is meant to be reasonably simple to implement by service providers. A basic query will be done in a wavelength range for the different services. The service returns a list of spectral lines formatted as a VOTable. Thus, an implementation of the service may support additional search parameters (some which may be custom to that particular service) to more finely control the selection of spectral lines. The specification also describes how the search on extra parameters has to be done, making use of the support provided by the Simple Spectral Line Data Model (SSLDM [1])

  8. 17 CFR 37.7 - Additional requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... descriptions, terms and conditions or trading protocols or providing for a new system product functionality, by... description, trading protocol or description of the system functionality or by electronic notification of the... trading protocol or system functionality. (b) Material modifications. Notwithstanding the provisions...

  9. 17 CFR 37.7 - Additional requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... descriptions, terms and conditions or trading protocols or providing for a new system product functionality, by... description, trading protocol or description of the system functionality or by electronic notification of the... trading protocol or system functionality. (b) Material modifications. Notwithstanding the provisions...

  10. Implementation of two-party protocols in the noisy-storage model

    SciTech Connect

    Wehner, Stephanie; Curty, Marcos; Schaffner, Christian; Lo, Hoi-Kwong

    2010-05-15

    The noisy-storage model allows the implementation of secure two-party protocols under the sole assumption that no large-scale reliable quantum storage is available to the cheating party. No quantum storage is thereby required for the honest parties. Examples of such protocols include bit commitment, oblivious transfer, and secure identification. Here, we provide a guideline for the practical implementation of such protocols. In particular, we analyze security in a practical setting where the honest parties themselves are unable to perform perfect operations and need to deal with practical problems such as errors during transmission and detector inefficiencies. We provide explicit security parameters for two different experimental setups using weak coherent, and parametric down-conversion sources. In addition, we analyze a modification of the protocols based on decoy states.

  11. Implementation of two-party protocols in the noisy-storage model

    NASA Astrophysics Data System (ADS)

    Wehner, Stephanie; Curty, Marcos; Schaffner, Christian; Lo, Hoi-Kwong

    2010-05-01

    The noisy-storage model allows the implementation of secure two-party protocols under the sole assumption that no large-scale reliable quantum storage is available to the cheating party. No quantum storage is thereby required for the honest parties. Examples of such protocols include bit commitment, oblivious transfer, and secure identification. Here, we provide a guideline for the practical implementation of such protocols. In particular, we analyze security in a practical setting where the honest parties themselves are unable to perform perfect operations and need to deal with practical problems such as errors during transmission and detector inefficiencies. We provide explicit security parameters for two different experimental setups using weak coherent, and parametric down-conversion sources. In addition, we analyze a modification of the protocols based on decoy states.

  12. Microwave Protocols for Paraffin Microtechnique and In Situ Localization in Plants

    NASA Astrophysics Data System (ADS)

    Schichnes, Denise; Nemson, Jeff; Sohlberg, Lorraine; Ruzin, Steven E.

    1998-10-01

    : We have developed a microwave protocol for a paraffin-embedding microtechnique of the shoot apical meristem of ZEA MAYS and have successfully applied this protocol to other plant tissues. This protocol decreases the time required for all aspects of microtechnique tissue processing, including fixation (24 hr to 15 min), dehydration (73 hr to 10 min), and infiltration (96 hr to 3 hr). Additionally, the time required to adhere paraffin ribbons to gelatin-coated slides and for the Johanson's safranin O, fast green FCF staining protocol has been significantly decreased. Using this technique, the quality of tissue preservation and subsequent in situ localization of KNOTTED mRNA was increased by using microwaves.

  13. Mutagenesis in Newts: Protocol for Iberian Ribbed Newts.

    PubMed

    Hayashi, Toshinori; Takeuchi, Takashi

    2016-01-01

    Newts have the remarkable capability of organ/tissue regeneration, and have been used as a unique experimental model for regenerative biology. The Iberian ribbed newt (Pleurodeles waltl) is suitable as a model animal. We have established methods for artificial insemination and efficient transgenesis using P. waltl newts. In addition to the transgenic technique, development of TALENs enables targeting mutagenesis in the newts. We have reported that TALENs efficiently disrupted targeted genes in newt embryos. In this chapter, we introduce a protocol for TALEN-mediated gene targeting in Iberian ribbed newts. PMID:26443218

  14. SP-NET: A draft signal processor network protocol

    NASA Astrophysics Data System (ADS)

    Burns, David M.

    SP-net, a synchronous high-speed switched network that has been designed for signal processor backplanes, is discussed. The network uses bit-slicing to improve fault tolerance and to allow growth in the width of the data path. In addition, single-bit error detection has been included in the protocol. Although no company at present is building a network to the draft SP-net specifications, SP-net has several similarities to signal processor network designs by major defense contractors.

  15. Mutagenesis in Newts: Protocol for Iberian Ribbed Newts.

    PubMed

    Hayashi, Toshinori; Takeuchi, Takashi

    2016-01-01

    Newts have the remarkable capability of organ/tissue regeneration, and have been used as a unique experimental model for regenerative biology. The Iberian ribbed newt (Pleurodeles waltl) is suitable as a model animal. We have established methods for artificial insemination and efficient transgenesis using P. waltl newts. In addition to the transgenic technique, development of TALENs enables targeting mutagenesis in the newts. We have reported that TALENs efficiently disrupted targeted genes in newt embryos. In this chapter, we introduce a protocol for TALEN-mediated gene targeting in Iberian ribbed newts.

  16. Generation of Insulin-Producing Cells from Human Bone Marrow-Derived Mesenchymal Stem Cells: Comparison of Three Differentiation Protocols

    PubMed Central

    Gabr, Mahmoud M.; Zakaria, Mahmoud M.; Refaie, Ayman F.; Khater, Sherry M.; Ashamallah, Sylvia A.; Ismail, Amani M.; El-Badri, Nagwa; Ghoneim, Mohamed A.

    2014-01-01

    Introduction. Many protocols were utilized for directed differentiation of mesenchymal stem cells (MSCs) to form insulin-producing cells (IPCs). We compared the relative efficiency of three differentiation protocols. Methods. Human bone marrow-derived MSCs (HBM-MSCs) were obtained from three insulin-dependent type 2 diabetic patients. Differentiation into IPCs was carried out by three protocols: conophylline-based (one-step protocol), trichostatin-A-based (two-step protocol), and β-mercaptoethanol-based (three-step protocol). At the end of differentiation, cells were evaluated by immunolabeling for insulin production, expression of pancreatic endocrine genes, and release of insulin and c-peptide in response to increasing glucose concentrations. Results. By immunolabeling, the proportion of generated IPCs was modest (≃3%) in all the three protocols. All relevant pancreatic endocrine genes, insulin, glucagon, and somatostatin, were expressed. There was a stepwise increase in insulin and c-peptide release in response to glucose challenge, but the released amounts were low when compared with those of pancreatic islets. Conclusion. The yield of functional IPCs following directed differentiation of HBM-MSCs was modest and was comparable among the three tested protocols. Protocols for directed differentiation of MSCs need further optimization in order to be clinically meaningful. To this end, addition of an extracellular matrix and/or a suitable template should be attempted. PMID:24818157

  17. The Space Communications Protocol Standards Program

    NASA Astrophysics Data System (ADS)

    Jeffries, Alan; Hooke, Adrian J.

    1994-11-01

    In the fall of 1992 NASA and the Department of Defense chartered a technical team to explore the possibility of developing a common set of space data communications standards for potential dual-use across the U.S. national space mission support infrastructure. The team focused on the data communications needs of those activities associated with on-lined control of civil and military aircraft. A two-pronged approach was adopted: a top-down survey of representative civil and military space data communications requirements was conducted; and a bottom-up analysis of available standard data communications protocols was performed. A striking intersection of civil and military space mission requirements emerged, and an equally striking consensus on the approach towards joint civil and military space protocol development was reached. The team concluded that wide segments of the U.S. civil and military space communities have common needs for: (1) an efficient file transfer protocol; (2) various flavors of underlying data transport service; (3) an optional data protection mechanism to assure end-to-end security of message exchange; and (4) an efficient internetworking protocol. These recommendations led to initiating a program to develop a suite of protocols based on these findings. This paper describes the current status of this program.

  18. Standardized North American marsh bird monitoring protocol

    USGS Publications Warehouse

    Conway, Courtney J.

    2011-01-01

    Little is known about the population status of many marsh-dependent birds in North America but recent efforts have focused on collecting more reliable information and estimates of population trends. As part of that effort, a standardized survey protocol was developed in 1999 that provided guidance for conducting marsh bird surveys throughout North America such that data would be consistent among locations. The original survey protocol has been revised to provide greater clarification on many issues as the number of individuals using the protocol has grown. The Standardized North American Marsh Bird Monitoring Protocol instructs surveyors to conduct an initial 5-minute passive point-count survey followed by a series of 1-minute segments during which marsh bird calls are broadcast into the marsh following a standardized approach. Surveyors are instructed to record each individual bird from the suite of 26 focal species that are present in their local area on separate lines of a datasheet and estimate the distance to each bird. Also, surveyors are required to record whether each individual bird was detected within each 1-minute subsegment of the survey. These data allow analysts to use several different approaches for estimating detection probability. The Standardized North American Marsh Bird Monitoring Protocol provides detailed instructions that explain the field methods used to monitor marsh birds in North America.

  19. Sensitive localized surface plasmon resonance multiplexing protocols.

    PubMed

    Jia, Kun; Bijeon, Jean L; Adam, Pierre M; Ionescu, Rodica E

    2012-09-18

    Herein are reported two new protocols to obtain different zones of localized surface plasmon resonance (LSPR) gold nanostructures on single glass substrate by using a vacuum evaporation technique followed by a high-temperature annealing (550 °C). The thickness of the gold film, considered as the essential parameter to determine specific LSPR properties, is successfully modulated. In the first protocol, a metal mask is integrated onto the glass substrate during vacuum evaporation to vary the gold film thickness by a "shadowing effect", while in the second protocol several evaporation cycles (up to four cycles) at predefined areas onto the single substrate are performed. The resulting gold-modified samples are characterized using a transmission UV-vis extinction optical setup and scanning electron microscopy (SEM). The size distribution histograms of nanoparticles are also acquired. By employing the first protocol, thanks to the presence of different zones of gold nanoparticles on a single substrate, optimized LSPR responses to different (bio)functionalization zones are rapidly screened. Independently, the second protocol exhibited an excellent correlation between the nominative evaporated gold film thickness, gold nanoparticle sizes, and plasmonic properties (resonant wavelength and peak amplitude). Such substrates are further used in the construction of LSPR immunosensors for the detection of atrazine herbicide.

  20. The Interplanetary Overlay Networking Protocol Accelerator

    NASA Technical Reports Server (NTRS)

    Pang, Jackson; Torgerson, Jordan L.; Clare, Loren P.

    2008-01-01

    A document describes the Interplanetary Overlay Networking Protocol Accelerator (IONAC) an electronic apparatus, now under development, for relaying data at high rates in spacecraft and interplanetary radio-communication systems utilizing a delay-tolerant networking protocol. The protocol includes provisions for transmission and reception of data in bundles (essentially, messages), transfer of custody of a bundle to a recipient relay station at each step of a relay, and return receipts. Because of limitations on energy resources available for such relays, data rates attainable in a conventional software implementation of the protocol are lower than those needed, at any given reasonable energy-consumption rate. Therefore, a main goal in developing the IONAC is to reduce the energy consumption by an order of magnitude and the data-throughput capability by two orders of magnitude. The IONAC prototype is a field-programmable gate array that serves as a reconfigurable hybrid (hardware/ firmware) system for implementation of the protocol. The prototype can decode 108,000 bundles per second and encode 100,000 bundles per second. It includes a bundle-cache static randomaccess memory that enables maintenance of a throughput of 2.7Gb/s, and an Ethernet convergence layer that supports a duplex throughput of 1Gb/s.

  1. STATISTICAL PRINCIPLES FOR PROSPECTIVE STUDY PROTOCOLS:

    PubMed Central

    Langberg, Henning

    2012-01-01

    In the design of scientific studies it is essential to decide on which scientific questions one aims to answer, just as it is important to decide on the correct statistical methods to use to answer these questions. The correct use of statistical methods is crucial in all aspects of research to quantify relationships in data. Despite an increased focus on statistical content and complexity of biomedical research these topics remain difficult for most researchers. Statistical methods enable researchers to condense large spreadsheets with data into means, proportions, and difference between means, risk differences, and other quantities that convey information. One of the goals in biomedical research is to develop parsimonious models ‐ meaning as simple as possible. This approach is valid if the subsequent research report (the article) is written independent of whether the results are “statistically significant” or not. In the present paper we outline the considerations and suggestions on how to build a trial protocol, with an emphasis on having a rigorous protocol stage, always leading to a full article manuscript, independent of statistical findings. We conclude that authors, who find (rigorous) protocol writing too troublesome, will realize that they have already written the first half of the final paper if they follow these recommendations; authors simply need to change the protocols future tense into past tense. Thus, the aim of this clinical commentary is to describe and explain the statistical principles for trial protocols in terms of design, analysis, and reporting of findings. PMID:23091782

  2. Collection protocol for human pancreas.

    PubMed

    Campbell-Thompson, Martha L; Montgomery, Emily L; Foss, Robin M; Kolheffer, Kerwin M; Phipps, Gerald; Schneider, Lynda; Atkinson, Mark A

    2012-05-23

    This dissection and sampling procedure was developed for the Network for Pancreatic Organ Donors with Diabetes (nPOD) program to standardize preparation of pancreas recovered from cadaveric organ donors. The pancreas is divided into 3 main regions (head, body, tail) followed by serial transverse sections throughout the medial to lateral axis. Alternating sections are used for fixed paraffin and fresh frozen blocks and remnant samples are minced for snap frozen sample preparations, either with or without RNAse inhibitors, for DNA, RNA, or protein isolation. The overall goal of the pancreas dissection procedure is to sample the entire pancreas while maintaining anatomical orientation. Endocrine cell heterogeneity in terms of islet composition, size, and numbers is reported for human islets compared to rodent islets. The majority of human islets from the pancreas head, body and tail regions are composed of insulin-containing β-cells followed by lower proportions of glucagon-containing α-cells and somatostatin-containing δ-cells. Pancreatic polypeptide-containing PP cells and ghrelin-containing epsilon cells are also present but in small numbers. In contrast, the uncinate region contains islets that are primarily composed of pancreatic polypeptide-containing PP cells. These regional islet variations arise from developmental differences. The pancreas develops from the ventral and dorsal pancreatic buds in the foregut and after rotation of the stomach and duodenum, the ventral lobe moves and fuses with the dorsal. The ventral lobe forms the posterior portion of the head including the uncinate process while the dorsal lobe gives rise to the rest of the organ. Regional pancreatic variation is also reported with the tail region having higher islet density compared to other regions and the dorsal lobe-derived components undergoing selective atrophy in type 1 diabetes. Additional organs and tissues are often recovered from the organ donors and include pancreatic lymph

  3. Collection Protocol for Human Pancreas

    PubMed Central

    Campbell-Thompson, Martha L.; Montgomery, Emily L.; Foss, Robin M.; Kolheffer, Kerwin M.; Phipps, Gerald; Schneider, Lynda; Atkinson, Mark A.

    2012-01-01

    This dissection and sampling procedure was developed for the Network for Pancreatic Organ Donors with Diabetes (nPOD) program to standardize preparation of pancreas recovered from cadaveric organ donors. The pancreas is divided into 3 main regions (head, body, tail) followed by serial transverse sections throughout the medial to lateral axis. Alternating sections are used for fixed paraffin and fresh frozen blocks and remnant samples are minced for snap frozen sample preparations, either with or without RNAse inhibitors, for DNA, RNA, or protein isolation. The overall goal of the pancreas dissection procedure is to sample the entire pancreas while maintaining anatomical orientation. Endocrine cell heterogeneity in terms of islet composition, size, and numbers is reported for human islets compared to rodent islets 1. The majority of human islets from the pancreas head, body and tail regions are composed of insulin-containing β-cells followed by lower proportions of glucagon-containing α-cells and somatostatin-containing δ-cells. Pancreatic polypeptide-containing PP cells and ghrelin-containing epsilon cells are also present but in small numbers. In contrast, the uncinate region contains islets that are primarily composed of pancreatic polypeptide-containing PP cells 2. These regional islet variations arise from developmental differences. The pancreas develops from the ventral and dorsal pancreatic buds in the foregut and after rotation of the stomach and duodenum, the ventral lobe moves and fuses with the dorsal 3. The ventral lobe forms the posterior portion of the head including the uncinate process while the dorsal lobe gives rise to the rest of the organ. Regional pancreatic variation is also reported with the tail region having higher islet density compared to other regions and the dorsal lobe-derived components undergoing selective atrophy in type 1 diabetes4,5. Additional organs and tissues are often recovered from the organ donors and include pancreatic

  4. Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.

    PubMed

    Li, Rebecca H; Wacholtz, Mary C; Barnes, Mark; Boggs, Liam; Callery-D'Amico, Susan; Davis, Amy; Digilova, Alla; Forster, David; Heffernan, Kate; Luthin, Maeve; Lynch, Holly Fernandez; McNair, Lindsay; Miller, Jennifer E; Murphy, Jacquelyn; Van Campen, Luann; Wilenzick, Mark; Wolf, Delia; Woolston, Cris; Aldinger, Carmen; Bierer, Barbara E

    2016-04-01

    A novel Protocol Ethics Tool Kit ('Ethics Tool Kit') has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval. PMID:26811365

  5. Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees

    PubMed Central

    Li, Rebecca H; Wacholtz, Mary C; Barnes, Mark; Boggs, Liam; Callery-D'Amico, Susan; Davis, Amy; Digilova, Alla; Forster, David; Heffernan, Kate; Luthin, Maeve; Lynch, Holly Fernandez; McNair, Lindsay; Miller, Jennifer E; Murphy, Jacquelyn; Van Campen, Luann; Wilenzick, Mark; Wolf, Delia; Woolston, Cris; Aldinger, Carmen; Bierer, Barbara E

    2016-01-01

    A novel Protocol Ethics Tool Kit (‘Ethics Tool Kit’) has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval. PMID:26811365

  6. Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.

    PubMed

    Li, Rebecca H; Wacholtz, Mary C; Barnes, Mark; Boggs, Liam; Callery-D'Amico, Susan; Davis, Amy; Digilova, Alla; Forster, David; Heffernan, Kate; Luthin, Maeve; Lynch, Holly Fernandez; McNair, Lindsay; Miller, Jennifer E; Murphy, Jacquelyn; Van Campen, Luann; Wilenzick, Mark; Wolf, Delia; Woolston, Cris; Aldinger, Carmen; Bierer, Barbara E

    2016-04-01

    A novel Protocol Ethics Tool Kit ('Ethics Tool Kit') has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval.

  7. Minimization of Hypoglycemia as an Adverse Event During Insulin Infusion: Further Refinement of the Yale Protocol

    PubMed Central

    Inzucchi, Silvio E.; Besterman, Brian J.

    2016-01-01

    Abstract Background: The management of hyperglycemia in the intensive care unit has been a controversial topic for more than a decade, with target ranges varying from 80–110 mg/dL to <200 mg/dL. Multiple insulin infusion protocols exist, including several computerized protocols, which have attempted to achieve these targets. Importantly, compliance with these protocols has not been a focus of clinical studies. Methods: GlucoCare™, a Food and Drug Administration (FDA)-cleared insulin-dosing calculator, was originally designed based on the Yale Insulin Infusion Protocol to target 100–140 mg/dL and has undergone several modifications to reduce hypoglycemia. The original Yale protocol was modified from 100–140 mg/dL to a range of 120–140 mg/dL (GlucoCare 120–140) and then to 140 mg/dL (GlucoCare 140, not a range but a single blood glucose [BG] level target) in an iterative and evidence-based manner to eliminate hypoglycemia <70 mg/dL. The final modification [GlucoCare 140(B)] includes the addition of bolus insulin “midprotocol” during an insulin infusion to reduce peak insulin rates for insulin-resistant patients. This study examined the results of these protocol modifications and evaluated the role of compliance with the protocol in the incidence of hypoglycemia <70 mg/dL. Results: Protocol modifications resulted in mean BG levels of 133.4, 136.4, 143.8, and 146.4 mg/dL and hypoglycemic BG readings <70 mg/dL of 0.998%, 0.367%, 0.256%, and 0.04% for the 100–140, 120–140, 140, and 140(B) protocols, respectively (P < 0.001). Adherence to the glucose check interval significantly reduced the incidence of hypoglycemia (P < 0.001). Protocol modifications led to a reduction in peak insulin infusion rates (P < 0.001) and the need for dextrose-containing boluses (P < 0.001). Conclusion: This study demonstrates that refinements in protocol design can improve glucose control in critically ill patients and that the use of

  8. Image guidance protocols: balancing imaging parameters against scan time

    PubMed Central

    Scaife, J E; Tudor, G S J; Jena, R; Romanchikova, M; Dean, J C; Hoole, A C F; Simmons, M P D; Burnet, N G

    2013-01-01

    Objective: Optimisation of imaging protocols is essential to maximise the use of image-guided radiotherapy. This article evaluates the time for daily online imaging with TomoTherapy® (Accuray®, Sunnyvale, CA), separating mechanical scan acquisition from radiographer-led image matching, to estimate the time required for a clinical research study (VoxTox). Methods: Over 5 years, 18 533 treatments were recorded for 3 tumour sites of interest (prostate, head and neck and central nervous system). Data were collected for scan length, number of CT slices, slice thickness, scan acquisition time and image matching time. Results: The proportion of coarse thickness scans increased over time, with a move of making coarse scans as the default. There was a strong correlation between scan time and scan length. Scan acquisition requires 40 s of processing time. For coarse scans, each additional centimetre requires 8 s for acquisition. Image matching takes approximately 1.5 times as long, so each additional centimetre needs 20 s extra in total. Modest changes to the imaging protocol have minimal impact over the course of the day. Conclusion: This work quantified the effect of changes to clinical protocols required for research. The results have been found to be reassuring in the busy National Institutes of Health department. Advances in knowledge This novel method of data collection and analysis provides evidence of the minimal impact of research on clinical turnover. Whilst the data relate specifically to TomoTherapy, some aspects may apply to other platforms in the future. PMID:24128423

  9. Automated plan-recognition of chemotherapy protocols

    PubMed Central

    Bhatia, Haresh; Levy, Mia

    2011-01-01

    Cancer patients are often treated with multiple sequential chemotherapy protocols ranging in complexity from simple to highly complex patterns of multiple repeating drugs. Clinical documentation procedures that focus on details of single drug events, however, make it difficult for providers and systems to efficiently abstract the sequence and nature of treatment protocols. We have developed a data driven method for cancer treatment plan recognition that takes as input pharmacy chemotherapy dispensing records and produces the sequence of identified chemotherapy protocols. Compared to a manually annotated gold standard, our method was 75% accurate and 80% precise for a breast cancer testing set (110 patients, 2,029 drug events), and 54% accurate and 63% precise for a lung cancer testing set (53 patients, 670 drug events). This method for cancer treatment plan recognition may provide clinicians and systems an abstracted view of the patient’s treatment history. PMID:22195061

  10. Efficient Controlled Quantum Secure Direct Communication Protocols

    NASA Astrophysics Data System (ADS)

    Patwardhan, Siddharth; Moulick, Subhayan Roy; Panigrahi, Prasanta K.

    2016-07-01

    We study controlled quantum secure direct communication (CQSDC), a cryptographic scheme where a sender can send a secret bit-string to an intended recipient, without any secure classical channel, who can obtain the complete bit-string only with the permission of a controller. We report an efficient protocol to realize CQSDC using Cluster state and then go on to construct a (2-3)-CQSDC using Brown state, where a coalition of any two of the three controllers is required to retrieve the complete message. We argue both protocols to be unconditionally secure and analyze the efficiency of the protocols to show it to outperform the existing schemes while maintaining the same security specifications.

  11. Chapter 22: Compressed Air Evaluation Protocol

    SciTech Connect

    Benton, N.

    2014-11-01

    Compressed-air systems are used widely throughout industry for many operations, including pneumatic tools, packaging and automation equipment, conveyors, and other industrial process operations. Compressed-air systems are defined as a group of subsystems composed of air compressors, air treatment equipment, controls, piping, pneumatic tools, pneumatically powered machinery, and process applications using compressed air. A compressed-air system has three primary functional subsystems: supply, distribution, and demand. Air compressors are the primary energy consumers in a compressed-air system and are the primary focus of this protocol. The two compressed-air energy efficiency measures specifically addressed in this protocol are: high-efficiency/variable speed drive (VSD) compressor replacing modulating compressor; compressed-air leak survey and repairs. This protocol provides direction on how to reliably verify savings from these two measures using a consistent approach for each.

  12. Chapter 15: Commercial New Construction Protocol

    SciTech Connect

    Keates, S.

    2014-09-01

    This protocol is intended to describe the recommended method when evaluating the whole-building performance of new construction projects in the commercial sector. The protocol focuses on energy conservation measures (ECMs) measures (or packages of measures) where evaluators can best analyze impacts using building simulation. These ECMs typically require the use of calibrated building simulations under Option D of the International Performance Measurement and Verification Protocol. Examples of such measures include Leadership in Energy and Environmental Design building certification, novel and/or efficient heating, ventilation, and air conditioning system designs, and extensive building controls systems. In general, it is best to evaluate any ECM (or set of measures) expected to significantly interact with other systems within the building and with savings sensitive to seasonal variations in weather.

  13. An object-oriented communication protocol

    NASA Astrophysics Data System (ADS)

    Chapman, Lee J.

    1990-08-01

    OOC is a high-level (OSI application layer and above) controls communication protocol. While natural languages are too complex for the controls environment, computer protocols are often insufficiently expressive. OOC is an attempt to balance simplicity and expressivity, and is sufficiently flexible to express data acquisition, control requests, alarm messages and error messages in a straightforward generic way. OOC supports dynamic creation of objects. It can be used in networks, for intertask and even for intratask communication. OOC, the protocol, is supported by OOC, the code, written in portable C. The lower level of this code supports a tagged-data scheme, with tags as elementary as INTEGER and BOOLEAN and as complex as OBJECT and MESSAGE. These tagged data can be evaluated in a LISP-like way.

  14. A class-chest for deriving transport protocols

    SciTech Connect

    Strayer, W.T.

    1996-10-01

    Development of new transport protocols or protocol algorithms suffers from the complexity of the environment in which they are intended to run. Modeling techniques attempt to avoid this by simulating the environment. Another approach to promoting rapid prototyping of protocols and protocol algorithms is to provide a pre-built infrastructure that is common to transport protocols, so that the focus is placed on the protocol-specific aspects. The Meta-Transport Library is a library of C++ base classes that implement or abstract out the mundane functions of a protocol, new protocol implementations are derived from base classes. The result is a fully viable user- level transport protocol implementation, with emphasis on modularity. The collection of base classes form a ``class-chest`` of tools .from which protocols can be developed and studied with as little change to a normal UNIX environment as possible.

  15. Cryptanalysis of the Quantum Group Signature Protocols

    NASA Astrophysics Data System (ADS)

    Zhang, Ke-Jia; Sun, Ying; Song, Ting-Ting; Zuo, Hui-Juan

    2013-11-01

    Recently, the researches of quantum group signature (QGS) have attracted a lot of attentions and some typical protocols have been designed for e-payment system, e-government, e-business, etc. In this paper, we analyze the security of the quantum group signature with the example of two novel protocols. It can be seen that both of them cannot be implemented securely since the arbitrator cannot solve the disputes fairly. In order to show that, some possible attack strategies, which can be used by the malicious participants, are proposed. Moreover, the further discussions of QGS are presented finally, including some insecurity factors and improved ideas.

  16. A Protocol for Evaluating Contextual Design Principles

    PubMed Central

    Stamps, Arthur

    2014-01-01

    This paper explains how scientific data can be incorporated into urban design decisions, such as evaluating contextual design principles. The recommended protocols are based on the Cochrane Reviews that have been widely used in medical research. The major concepts of a Cochrane Review are explained, as well as the underlying mathematics. The underlying math is meta-analysis. Data are reported for three applications and seven contextual design policies. It is suggested that use of the Cochrane protocols will be of great assistance to planners by providing scientific data that can be used to evaluate the efficacies of contextual design policies prior to implementing those policies. PMID:25431448

  17. Building multiservice Internet protocol virtual private networks

    NASA Astrophysics Data System (ADS)

    Cheung, William

    1999-11-01

    Multiservice Internet Protocol-based Virtual Private Networks (MIP- VPNs) with Quality of Service (QoS) are becoming a reality due to the availability of new standards from the Internet Engineering Task Force (IETF). This paper describes how components including security models, IP tunneling protocols, and service differentiation schemes fit together in order to construct such a VPN. First, the concept and rationale of VPN is presented, followed by a discussion of its supporting components. A comparison is made among the various VPN technologies.

  18. Social Protocols for Agile Virtual Teams

    NASA Astrophysics Data System (ADS)

    Picard, Willy

    Despite many works on collaborative networked organizations (CNOs), CSCW, groupware, workflow systems and social networks, computer support for virtual teams is still insufficient, especially support for agility, i.e. the capability of virtual team members to rapidly and cost efficiently adapt the way they interact to changes. In this paper, requirements for computer support for agile virtual teams are presented. Next, an extension of the concept of social protocol is proposed as a novel model supporting agile interactions within virtual teams. The extended concept of social protocol consists of an extended social network and a workflow model.

  19. The Parasol Protocol for computational mutagenesis.

    PubMed

    Aronica, P G A; Verma, C; Popovic, B; Leatherbarrow, R J; Gould, I R

    2016-07-01

    To aid in the discovery and development of peptides and proteins as therapeutic agents, a virtual screen can be used to predict trends and direct workflow. We have developed the Parasol Protocol, a dynamic method implemented using the AMBER MD package, for computational site-directed mutagenesis. This tool can mutate between any pair of amino acids in a computationally expedient, automated manner. To demonstrate the potential of this methodology, we have employed the protocol to investigate a test case involving stapled peptides, and have demonstrated good agreement with experiment. PMID:27255759

  20. NADA protocol: integrative acupuncture in addictions.

    PubMed

    Carter, Kenneth; Olshan-Perlmutter, Michelle

    2014-01-01

    National Acupuncture Detoxification Association (NADA) acupuncture is a simple, standardized, 1- to 5-point auricular needling protocol that originated as a grass-roots response to the opiate epidemic of the 1970s. NADA acupuncture is increasingly recognized as a universally useful intervention in the treatment of addictions specifically and in behavior health more generally. It is recognized as a best practice in the treatment of substance use disorders. Integrative programs using the NADA protocol are likely to see improvements in engagement, retention, decreased drug cravings, anxiety, and less physical symptoms.

  1. Quantum Private Comparison Protocol with Linear Optics

    NASA Astrophysics Data System (ADS)

    Luo, Qing-bin; Yang, Guo-wu; She, Kun; Li, Xiaoyu

    2016-09-01

    In this paper, we propose an innovative quantum private comparison(QPC) protocol based on partial Bell-state measurement from the view of linear optics, which enabling two parties to compare the equality of their private information with the help of a semi-honest third party. Partial Bell-state measurement has been realized by using only linear optical elements in experimental measurement-device-independent quantum key distribution(MDI-QKD) schemes, which makes us believe that our protocol can be realized in the near future. The security analysis shows that the participants will not leak their private information.

  2. The Trier Social Stress Test protocol for inducing psychological stress.

    PubMed

    Birkett, Melissa A

    2011-10-19

    This article demonstrates a psychological stress protocol for use in a laboratory setting. Protocols that allow researchers to study the biological pathways of the stress response in health and disease are fundamental to the progress of research in stress and anxiety. Although numerous protocols exist for inducing stress response in the laboratory, many neglect to provide a naturalistic context or to incorporate aspects of social and psychological stress. Of psychological stress protocols, meta-analysis suggests that the Trier Social Stress Test (TSST) is the most useful and appropriate standardized protocol for studies of stress hormone reactivity. In the original description of the TSST, researchers sought to design and evaluate a procedure capable of inducing a reliable stress response in the majority of healthy volunteers. These researchers found elevations in heart rate, blood pressure and several endocrine stress markers in response to the TSST (a psychological stressor) compared to a saline injection (a physical stressor). Although the TSST has been modified to meet the needs of various research groups, it generally consists of a waiting period upon arrival, anticipatory speech preparation, speech performance, and verbal arithmetic performance periods, followed by one or more recovery periods. The TSST requires participants to prepare and deliver a speech, and verbally respond to a challenging arithmetic problem in the presence of a socially evaluative audience. Social evaluation and uncontrollability have been identified as key components of stress induction by the TSST. In use for over a decade, the goal of the TSST is to systematically induce a stress response in order to measure differences in reactivity, anxiety and activation of the hypothalamic-pituitary-adrenal (HPA) or sympathetic-adrenal-medullary (SAM) axis during the task. Researchers generally assess changes in self-reported anxiety, physiological measures (e.g. heart rate), and

  3. Interpolation of recurrence and hashing entanglement distillation protocols

    SciTech Connect

    Vollbrecht, Karl Gerd H.; Verstraete, Frank

    2005-06-15

    We construct interesting entanglement distillation protocols by interpolating between the recurrence and hashing protocols. This leads to asymptotic two-way distillation protocols, resulting in an improvement of the distillation rate for all mixed Bell diagonal entangled states, even for the ones with very high fidelity. We also present a method for how entanglement-assisted distillation protocol can be converted into nonentanglement-assisted protocols with the same yield.

  4. A blueprint for a sepsis protocol.

    PubMed

    Shapiro, Nathan I; Howell, Michael; Talmor, Daniel

    2005-04-01

    Despite numerous advances in medicine, sepsis remains an unconquered challenge. Although outcomes have improved slightly over decades, the unacceptably high mortality rate of 30%-50% for severe sepsis and septic shock continues. However, after years of unsuccessful clinical trials, several investigations over the last few years have reported survival benefit in the treatment of sepsis. Physicians now have several proven therapies to treat sepsis, but have yet to implement them on a widespread, systematic basis. This led 11 international professional societies spanning multiple specialties and continents to come together to create the Surviving Sepsis Campaign. The product of their work is an international effort organized to improve care of patients with sepsis and includes consensus, evidence-based guidelines for care that improves survival in septic patients, and an action plan for change. Given the clear role of early identification and treatment in stopping the sepsis cascade, therapy must start early in the emergency department (ED) and continue throughout the hospital course. The first of the recommendations by the Surviving Sepsis Campaign is the aggressive resuscitation strategy of early goal-directed therapy (EGDT). EGDT is reported to reduce absolute mortality by a staggering 16%. The use of recombinant activated protein C was demonstrated to confer a 6% absolute survival benefit. Steroid supplementation in adrenal insufficiency produced a 10% benefit. Additionally, early and appropriate use of antibiotics remains a cornerstone of therapy. Although no randomized trial will be performed, the effects are undisputed. Finally, although predominantly intensive care unit therapies, tight glucose control and low-tidal-volume ventilation strategies have also led to improved survival. Armed with these new therapies, the medical community must rise to this call to action. Clinicians must change the approach to this disease, as well as the way the septic patient is

  5. Effect of an additional atropine injection during dobutamine infusion for myocardial SPET.

    PubMed

    Caner, B; Karanfil, A; Uysal, U; Tokgozoglu, L; Aksoyek, S; Ugur, O; Ciftci, I; Atalar, E; Kes, S; Bekdik, C

    1997-06-01

    The aim of this study was to examine the value of an additional atropine injection in patients who do not achieve an adequate heart rate during dobutamine infusion for myocardial perfusion SPET (single photon emission tomography). Patients undergoing dobutamine myocardial SPET who failed to achieve > or = 85% of their age-predicted maximal heart rate at the end of dobutamine infusion (D protocol) had a second dobutamine myocardial SPET study on a separate day with the addition of an atropine injection during the dobutamine infusion (D + A protocol). Twenty-nine patients were studied. 201Tl was used in 27 patients and 99Tc(m)-MIBI in two patients. All patients underwent coronary angiography and significant coronary artery disease was found in 19 of 29 patients. The mean heart rate obtained at the peak of dobutamine infusion in the D + A protocol was significantly higher than that in the D protocol (153.8 +/- 13.8 vs 117.5 +/- 15.3 beats min[-1]). The D + A protocol resulted in a higher diagnostic sensitivity for the detection of stenosed coronaries compared with the D protocol (87 vs 80%, P > 0.05) without changing the specificity (89% for both protocols). On the other hand, the frequency of side-effects and ECG changes during the D + A protocol was higher than that with the D protocol (32 vs 47). In conclusion, the addition of an atropine injection during dobutamine infusion resulted in a higher diagnostic sensitivity for identifying stenosed coronaries compared to dobutamine alone.

  6. Development of a Protocol for Simultaneous Assessment of Cognitive Functioning Under Psychosocial Stress.

    PubMed

    Marko, Martin

    2016-10-01

    This study presents a protocol for induction of moderate psychosocial stress and investigates its impact on psychological and physiological responses. The proposed procedure was designed to enable researchers to assess cognitive performance under effect of various classes of stressors. The protocol's structure contains three main periods: baseline, assessment, and recovery. The assessment stage starts with task anticipation, during which audience (three-member commission) is introduced and apparatus (cameras, microphones, lights, and physiological measuring devices) stationed. Subsequently, cognitive performance was tested. The protocol was evaluated on 56 university students that were randomly assigned to control or stress (protocol) treatment and administered three cognitive tests (working memory operation span, remote associates test, and semantic fluency). Compared to control sessions, protocol induced state anxiety, interfering worry thoughts, and disturbance during recovery period. In addition, the stress group also showed elevated levels of skin conductance, higher average heart rates, and larger drops in peripheral temperature. Even though more research is needed, these results suggest that the protocol effectively induces both psychological and physiological stress responses and therefore encourages utilization in cognitive-affective and cognitive-biological fields of research. PMID:27467447

  7. Practical security analysis of a quantum stream cipher by the Yuen 2000 protocol

    SciTech Connect

    Hirota, Osamu

    2007-09-15

    There exists a great gap between one-time pad with perfect secrecy and conventional mathematical encryption. The Yuen 2000 (Y00) protocol or {alpha}{eta} scheme may provide a protocol which covers from the conventional security to the ultimate one, depending on implementations. This paper presents the complexity-theoretic security analysis on some models of the Y00 protocol with nonlinear pseudo-random-number-generator and quantum noise diffusion mapping (QDM). Algebraic attacks and fast correlation attacks are applied with a model of the Y00 protocol with nonlinear filtering like the Toyocrypt stream cipher as the running key generator, and it is shown that these attacks in principle do not work on such models even when the mapping between running key and quantum state signal is fixed. In addition, a security property of the Y00 protocol with QDM is clarified. Consequently, we show that the Y00 protocol has a potential which cannot be realized by conventional cryptography and that it goes beyond mathematical encryption with physical encryption.

  8. LINCS Authentication Domain Interface (ADI) Logon protocol. (Preliminary specification and implementation guide)

    SciTech Connect

    Nessett, D.M.; Fletcher, J.G.

    1984-10-11

    With the development of computer networking a need has arisen for users to interact with various computers and distributed operating systems from terminals remotely located from those systems. By remotely located terminals we mean those connected to networks using a different protocol family than the computer or distributed operating system being logged onto. Each terminal is said to belong to an authentication domain (NESD84). We express the above requirement as the desirability to provide inter-authentication-domain interactive services. The problems and attendant requirements of accomplishing inter-authentication-domain interactive services are discussed in (NESD84). Readers are assumed to be familiar with the concepts and protocol defined in that document. This specification defines the Authentication Domain Interface (ADI) Logon protocol for the LINCS distributed operating system that in conjunction with the Inter-Authentication-Domain Logon protocol gives users of LINCS terminals the ability to logon to hosts that do not support LINCS. Hereafter, the Inter-Authentication-Domain Logon Protocol is called the IAD Logon protocol for the sake of brevity. In addition, it gives users of terminals connected to networks that do not directly support LINCS the ability to logon and use LINCS distributed resources.

  9. Optimization and Evaluation Strategy of Esophageal Tissue Preparation Protocols for Metabolomics by LC-MS.

    PubMed

    Wang, Huiqing; Xu, Jing; Chen, Yanhua; Zhang, Ruiping; He, Jiuming; Wang, Zhonghua; Zang, Qingce; Wei, Jinfeng; Song, Xiaowei; Abliz, Zeper

    2016-04-01

    Sample preparation is a critical step in tissue metabolomics. Therefore, a comprehensive and systematic strategy for the screening of tissue preparation protocols is highly desirable. In this study, we developed an Optimization and Evaluation Strategy based on LC-MS to screen for a high-extractive efficiency and reproducible esophageal tissue preparation protocol for different types of endogenous metabolites (amino acids, carnitines, cholines, etc.), with a special focus on low-level metabolites. In this strategy, we first selected a large number of target metabolites based on literature survey, previous work in our lab, and known metabolic pathways. For these target metabolites, we tested different solvent extraction methods (biphasic solvent extraction, two-step [TS], stepwise [SW], all-in one [AO]; single-phase solvent extraction, SP) and esophageal tissue disruption methods (homogenized wet tissue [HW], ground wet tissue [GW], and ground dry tissue [GD]). A protocol involving stepwise addition of solvents and a homogenized wet tissue protocol (SWHW) was superior to the others. Finally, we evaluated the stability of endogenous metabolites in esophageal tissues and the sensitivity, reproducibility, and recovery of the optimal protocol. The results proved that the SWHW protocol was robust and adequate for bioanalysis. This strategy will provide important guidance for the standardized and scientific investigation of tissue metabolomics.

  10. Development of a Canadian Standardized Protocol for Subtyping Methicillin-Resistant Staphylococcus aureus Using Pulsed-Field Gel Electrophoresis

    PubMed Central

    Mulvey, M. R.; Chui, L.; Ismail, J.; Louie, L.; Murphy, C.; Chang, N.; Alfa, M.

    2001-01-01

    A panel of 24 methicillin-resistant Staphylococcus aureus strains was distributed to 15 laboratories in Canada to evaluate their in-house pulsed-field gel electrophoresis (PFGE) protocols and interpretation criteria. Attempts to compare fingerprint images using computer-aided analysis were not successful due to variability in individual laboratory PFGE protocols. In addition, individual site interpretation of the fingerprint patterns was inadequate, as 7 of 13 sites (54%) made at least one error in interpreting the fingerprints from the panel. A 2-day standardized PFGE protocol (culture to gel image) was developed and distributed to all of the sites. Each site was requested to use the standardized protocol on five strains from the original panel. Thirteen sites submitted gel images for comparisons. The protocol demonstrated excellent reproducibility and allowed interlaboratory comparisons with Molecular Analyst DST software (Bio-Rad) and 1.5% band tolerance. PMID:11574559

  11. Dynamic vs. fixed bag filling: impact on cardiac output rebreathing protocol.

    PubMed

    Zavorsky, Gerald S; Beck, Kenneth C; Cass, Lauren M; Artal, Raul; Wagner, Peter D

    2010-04-15

    The purpose of this study was to compare the repeatability (2.77 multiplied by the within-subject SD)between two different rebreathing protocols on cardiac output ( ˙Q ), pulmonary diffusing capacity for carbon monoxide (DLCO) and nitric oxide (DLNO), and pulmonary capillary blood volume (Vc). This study compared two bag volume protocols [Fixed Bag Volume (FBV) = bag volume fixed at 60% of forced vital capacity; Dynamic Bag Volume (DBV) = bag volume matched to tidal volume at each stage of exercise].Ten females (age = 27±8 yrs; ˙VO2, (peak)=2.5±0.6 L/min had measurements at rest (12%), 52%, 88%, and 100% of ˙VO2, (peak) on two study days. Neither the slope nor intercept of ˙Q vs. ˙VO2 were different between either bag volume protocols. The slope of DLCO vs. ˙Q was the same but the intercept was higher for the FBV protocol. The bag volume affected the slope and the intercept between DLNO vs. ˙Q (p < 0.05).The mean repeatability was similar between both protocols for ˙Q (2.0 vs. 2.3 L/min) and DLCO (3.8 vs.5.9 mL/min/mmHg), regardless of exercise intensity. Increasing exercise intensity made the measurement error worse for Vc and DLNO (p ≤ 0.06). Measurement error was lower for Vc when using the FBV protocol (p = 0.02). Also, the pattern of bag volume used during rebreathing maneuvers affected the relation between DLNO vs. ˙Q more than it affected DLCO vs. ˙Q , or Vc vs. ˙Q. Additionally, the FBV protocol provided less measurement error for Vc compared to the DBV protocol [corrected].

  12. Evaluating Computer-Tutors: A Protocol Study.

    ERIC Educational Resources Information Center

    Strickland, James

    A protocol study investigated whether computer tutors (programs that interactively guide writers while they freewrite with a word processing program) promote or hinder a richer understanding of the composing process. The analysis focused on writers' attitudes toward computer tutors in the invention process. Data were collected by tape recording a…

  13. 16 CFR 1212.4 - Test protocol.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... results and acceptance criterion. To determine whether a surrogate multi-purpose lighter resists operation... STANDARD FOR MULTI-PURPOSE LIGHTERS Requirements for Child-Resistance § 1212.4 Test protocol. (a) Child test panel. (1) The test to determine if a multi-purpose lighter is resistant to successful...

  14. Protocols for growing plant symbioses; mycorrhiza.

    PubMed

    Schultze, Michael

    2013-01-01

    Arbuscular mycorrhizal symbiosis is receiving increased attention as a potential contributor to sustainable crop plant nutrition. This chapter details a set of protocols for plant growth to study the development and physiology of the arbuscular mycorrhizal symbiosis, and how to establish root organ cultures for the production of axenic inoculum.

  15. Reliable multicasting in the Xpress Transport Protocol

    SciTech Connect

    Atwood, J.W.; Catrina, O.; Fenton, J.; Strayer, W.T.

    1996-12-01

    The Xpress Transport Protocol (XTP) is designed to meet the needs of distributed, real-time, and multimedia systems. This paper describes the genesis of recent improvements to XTP that provide mechanisms for reliable management of multicast groups, and gives details of the mechanisms used.

  16. A Geographical Heuristic Routing Protocol for VANETs.

    PubMed

    Urquiza-Aguiar, Luis; Tripp-Barba, Carolina; Aguilar Igartua, Mónica

    2016-01-01

    Vehicular ad hoc networks (VANETs) leverage the communication system of Intelligent Transportation Systems (ITS). Recently, Delay-Tolerant Network (DTN) routing protocols have increased their popularity among the research community for being used in non-safety VANET applications and services like traffic reporting. Vehicular DTN protocols use geographical and local information to make forwarding decisions. However, current proposals only consider the selection of the best candidate based on a local-search. In this paper, we propose a generic Geographical Heuristic Routing (GHR) protocol that can be applied to any DTN geographical routing protocol that makes forwarding decisions hop by hop. GHR includes in its operation adaptations simulated annealing and Tabu-search meta-heuristics, which have largely been used to improve local-search results in discrete optimization. We include a complete performance evaluation of GHR in a multi-hop VANET simulation scenario for a reporting service. Our study analyzes all of the meaningful configurations of GHR and offers a statistical analysis of our findings by means of MANOVA tests. Our results indicate that the use of a Tabu list contributes to improving the packet delivery ratio by around 5% to 10%. Moreover, if Tabu is used, then the simulated annealing routing strategy gets a better performance than the selection of the best node used with carry and forwarding (default operation). PMID:27669254

  17. 40 CFR 161.70 - Acceptable protocols.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ingredient, mixture, or product. Accordingly, failure to follow a suggested protocol will not invalidate a... part. Readers should note, however, that certain of the OECD recommended test standards, such as test duration and selection of test species, are less restrictive than those recommended by EPA. Therefore,...

  18. 21 CFR 312.30 - Protocol amendments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Protocol amendments. 312.30 Section 312.30 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE INVESTIGATIONAL NEW DRUG APPLICATION Investigational New Drug Application (IND) §...

  19. 21 CFR 312.83 - Treatment protocols.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Treatment protocols. 312.83 Section 312.83 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE INVESTIGATIONAL NEW DRUG APPLICATION Drugs Intended to Treat Life-threatening and...

  20. The Vocational Assessment Protocol: Development and Validation.

    ERIC Educational Resources Information Center

    Thomas, Dale F.; Menz, Fredrick E.

    This report describes a 48-month project which developed, field tested, and evaluated the utility of the Vocational Assessment Protocol (VAP) for use with persons with traumatic brain injury resulting in a severe and persistent disability. The VAP is intended to assist in the community-based vocational rehabilitation of these individuals. The VAP…

  1. A Geographical Heuristic Routing Protocol for VANETs.

    PubMed

    Urquiza-Aguiar, Luis; Tripp-Barba, Carolina; Aguilar Igartua, Mónica

    2016-09-23

    Vehicular ad hoc networks (VANETs) leverage the communication system of Intelligent Transportation Systems (ITS). Recently, Delay-Tolerant Network (DTN) routing protocols have increased their popularity among the research community for being used in non-safety VANET applications and services like traffic reporting. Vehicular DTN protocols use geographical and local information to make forwarding decisions. However, current proposals only consider the selection of the best candidate based on a local-search. In this paper, we propose a generic Geographical Heuristic Routing (GHR) protocol that can be applied to any DTN geographical routing protocol that makes forwarding decisions hop by hop. GHR includes in its operation adaptations simulated annealing and Tabu-search meta-heuristics, which have largely been used to improve local-search results in discrete optimization. We include a complete performance evaluation of GHR in a multi-hop VANET simulation scenario for a reporting service. Our study analyzes all of the meaningful configurations of GHR and offers a statistical analysis of our findings by means of MANOVA tests. Our results indicate that the use of a Tabu list contributes to improving the packet delivery ratio by around 5% to 10%. Moreover, if Tabu is used, then the simulated annealing routing strategy gets a better performance than the selection of the best node used with carry and forwarding (default operation).

  2. An international computer protocol standard is essential

    SciTech Connect

    Marks, J.

    1994-02-01

    This article examines the need for the development of an international communication protocol to avoid building or buying customized interfaces or gateways in order to connect two separate vendor's devices to the same computer. The article discuss the need for standards and details one electric cooperative's experience in converting their automated mapping and facilities management system to EPRI sponsored Utility Communications Architecture.

  3. Measurement Protocols for Optimized Fuel Assembly Tags

    SciTech Connect

    Gerlach, David C.; Mitchell, Mark R.; Reid, Bruce D.; Gesh, Christopher J.; Hurley, David E.

    2008-11-01

    This report describes the measurement protocols for optimized tags that can be applied to standard fuel assemblies used in light water reactors. This report describes work performed by the authors at Pacific Northwest National Laboratory for NA-22 as part of research to identify specific signatures that can be developed to support counter-proliferation technologies.

  4. Direct data access protocols benchmarking on DPM

    NASA Astrophysics Data System (ADS)

    Furano, Fabrizio; Devresse, Adrien; Keeble, Oliver; Mancinelli, Valentina

    2015-12-01

    The Disk Pool Manager is an example of a multi-protocol, multi-VO system for data access on the Grid that went though a considerable technical evolution in the last years. Among other features, its architecture offers the opportunity of testing its different data access frontends under exactly the same conditions, including hardware and backend software. This characteristic inspired the idea of collecting monitoring information from various testbeds in order to benchmark the behaviour of the HTTP and Xrootd protocols for the use case of data analysis, batch or interactive. A source of information is the set of continuous tests that are run towards the worldwide endpoints belonging to the DPM Collaboration, which accumulated relevant statistics in its first year of activity. On top of that, the DPM releases are based on multiple levels of automated testing that include performance benchmarks of various kinds, executed regularly every day. At the same time, the recent releases of DPM can report monitoring information about any data access protocol to the same monitoring infrastructure that is used to monitor the Xrootd deployments. Our goal is to evaluate under which circumstances the HTTP-based protocols can be good enough for batch or interactive data access. In this contribution we show and discuss the results that our test systems have collected under the circumstances that include ROOT analyses using TTreeCache and stress tests on the metadata performance.

  5. 40 CFR 792.120 - Protocol.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Justification for selection of the test system. (6) Where applicable, the number, body weight, sex, source of... than established by the specifications. (10) The route of administration and the reason for its choice... changes in or revisions of an approved protocol and the reasons therefor shall be documented, signed...

  6. 40 CFR 160.120 - Protocol.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... selection of the test system. (6) Where applicable, the number, body weight range, sex, source of supply... specifications. (10) The route of administration and the reason for its choice. (11) Each dosage level, expressed... of an approved protocol and the reasons therefore shall be documented, signed by the study...

  7. 40 CFR 160.120 - Protocol.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... selection of the test system. (6) Where applicable, the number, body weight range, sex, source of supply... specifications. (10) The route of administration and the reason for its choice. (11) Each dosage level, expressed... of an approved protocol and the reasons therefore shall be documented, signed by the study...

  8. 40 CFR 160.120 - Protocol.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... selection of the test system. (6) Where applicable, the number, body weight range, sex, source of supply... specifications. (10) The route of administration and the reason for its choice. (11) Each dosage level, expressed... of an approved protocol and the reasons therefore shall be documented, signed by the study...

  9. Teledermatology protocol for screening of Skin Cancer*

    PubMed Central

    Piccoli, Maria Fernanda; Amorim, Bruna Dücker Bastos; Wagner, Harley Miguel; Nunes, Daniel Holthausen

    2015-01-01

    BACKGROUND Telemedicine refers to the use of technology as improvement of healthcare delivery to places where distance becomes an obstacle. Its use represents a great potential for dermatology, a specialty whose visual analysis phase is essential in diagnosis. OBJECTIVES To analyze the compatibility index of skin cancer diagnoses between primary care and teledermatology, and to validate a protocol for standardization of digital imaging to obtain the reports in teledermatology. METHODS An observational cross-sectional study developed through the census of 333 examination requests, received between January/2012 and July/2012, in the Center for Telemedicine and Telehealth of SES-SC. We used a protocol for photographic lesion standardization, consisting of three steps (panoramic photo, close-up with ruler and dermoscopy). After collection, the data were sent to a virtual site on the Internet, and recorded with the use of an electronic health record containing the images, the skin phototype and demographic characteristics. RESULTS The level of compatibility between the diagnosis of skin cancer in Santa Catarina's primary care and the diagnosis proposed by teledermatology was 19.02%. Proportionally, it was 21.21% for BCC, 44.44% for SCC and 6.98% for MM. The protocol was statistically significant (p <0.05), with an OR of 38.77. CONCLUSION The rate of diagnostic compatibility of skin cancer was low and the use of the protocol optimized the chance of validating requests for examination. PMID:25830990

  10. A Generic Archive Protocol and an Implementation

    NASA Astrophysics Data System (ADS)

    Jordan, J. M.; Jennings, D. G.; McGlynn, T. A.; Ruggiero, N. G.; Serlemitsos, T. A.

    1993-01-01

    Archiving vast amounts of data has become a major part of every scientific space mission today. GRASP, the Generic Retrieval/Ar\\-chive Services Protocol, addresses the question of how to archive the data collected in an environment where the underlying hardware archives and computer hosts may be rapidly changing.

  11. 16 CFR 1210.4 - Test protocol.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of children from each 100-child test panel, photograph(s) or video tape to show how the lighter was... STANDARD FOR CIGARETTE LIGHTERS Requirements for Child Resistance § 1210.4 Test protocol. (a) Child test panel. (1) The test to determine if a lighter is resistant to successful operation by children uses...

  12. 16 CFR 1210.4 - Test protocol.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of children from each 100-child test panel, photograph(s) or video tape to show how the lighter was... STANDARD FOR CIGARETTE LIGHTERS Requirements for Child Resistance § 1210.4 Test protocol. (a) Child test panel. (1) The test to determine if a lighter is resistant to successful operation by children uses...

  13. 16 CFR 1210.4 - Test protocol.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... of children from each 100-child test panel, photograph(s) or video tape to show how the lighter was... STANDARD FOR CIGARETTE LIGHTERS Requirements for Child Resistance § 1210.4 Test protocol. (a) Child test panel. (1) The test to determine if a lighter is resistant to successful operation by children uses...

  14. 16 CFR 1212.4 - Test protocol.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... STANDARD FOR MULTI-PURPOSE LIGHTERS Requirements for Child-Resistance § 1212.4 Test protocol. (a) Child... by children uses a panel of children to test a surrogate multi-purpose lighter representing the... of a child before the child participates in the test. (2) The test shall be conducted using at...

  15. 16 CFR 1212.4 - Test protocol.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... STANDARD FOR MULTI-PURPOSE LIGHTERS Requirements for Child-Resistance § 1212.4 Test protocol. (a) Child... by children uses a panel of children to test a surrogate multi-purpose lighter representing the... of a child before the child participates in the test. (2) The test shall be conducted using at...

  16. 16 CFR 1212.4 - Test protocol.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... STANDARD FOR MULTI-PURPOSE LIGHTERS Requirements for Child-Resistance § 1212.4 Test protocol. (a) Child... by children uses a panel of children to test a surrogate multi-purpose lighter representing the... of a child before the child participates in the test. (2) The test shall be conducted using at...

  17. 16 CFR 1210.4 - Test protocol.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of children from each 100-child test panel, photograph(s) or video tape to show how the lighter was... STANDARD FOR CIGARETTE LIGHTERS Requirements for Child Resistance § 1210.4 Test protocol. (a) Child test panel. (1) The test to determine if a lighter is resistant to successful operation by children uses...

  18. Montreal Protocol benefits simulated with CCM SOCOL

    NASA Astrophysics Data System (ADS)

    Egorova, T.; Rozanov, E.; Gröbner, J.; Hauser, M.; Schmutz, W.

    2012-07-01

    Ozone depletion is caused by the anthropogenic increase of halogen containing species in the atmosphere, which results in the enhancement of the concentration of reactive chlorine and bromine in the stratosphere. To reduce the influence of anthropogenic ozone-depleting substances (ODS), the Montreal Protocol was agreed by Governments in 1987, with several Amendments adopted later. In order to assess the benefits of the Montreal Protocol and its Amendments (MPA) on ozone and UV radiation, two different runs of the chemistry-climate model (CCM) SOCOL have been carried out. The first run was driven by the emission of ozone depleting substances (ODS) prescribed according to the restrictions of the Montreal Protocol and all its Amendments. For the second run we allow the ODS to grow by 3% annually. We find that the MPA would have saved up to 80% of the global annual total ozone by the end of the 21st century. Our calculations also show substantial changes in surface temperature and precipitations that could occur in the world without MPA implementations. To illustrate the changes in UV radiation at the surface and to emphasize certain features which can only be seen for some particular regions if the influence of the cloud cover changes is accounted for, we calculate geographical distribution of the erythemally weighted irradiance (Eery). For the no Montreal Protocol simulation Eery increases by factor of 4 to 16 between the 1970s and 2100. For the scenario including the Montreal Protocol it is found that UV radiation starts to decrease in 2000, with continuous decline of 5% to 10% at middle latitudes in the Northern and Southern hemispheres.

  19. Bayesian adaptive survey protocols for resource management

    USGS Publications Warehouse

    Halstead, Brian J.; Wylie, Glenn D.; Coates, Peter S.; Casazza, Michael L.

    2011-01-01

    Transparency in resource management decisions requires a proper accounting of uncertainty at multiple stages of the decision-making process. As information becomes available, periodic review and updating of resource management protocols reduces uncertainty and improves management decisions. One of the most basic steps to mitigating anthropogenic effects on populations is determining if a population of a species occurs in an area that will be affected by human activity. Species are rarely detected with certainty, however, and falsely declaring a species absent can cause improper conservation decisions or even extirpation of populations. We propose a method to design survey protocols for imperfectly detected species that accounts for multiple sources of uncertainty in the detection process, is capable of quantitatively incorporating expert opinion into the decision-making process, allows periodic updates to the protocol, and permits resource managers to weigh the severity of consequences if the species is falsely declared absent. We developed our method using the giant gartersnake (Thamnophis gigas), a threatened species precinctive to the Central Valley of California, as a case study. Survey date was negatively related to the probability of detecting the giant gartersnake, and water temperature was positively related to the probability of detecting the giant gartersnake at a sampled location. Reporting sampling effort, timing and duration of surveys, and water temperatures would allow resource managers to evaluate the probability that the giant gartersnake occurs at sampled sites where it is not detected. This information would also allow periodic updates and quantitative evaluation of changes to the giant gartersnake survey protocol. Because it naturally allows multiple sources of information and is predicated upon the idea of updating information, Bayesian analysis is well-suited to solving the problem of developing efficient sampling protocols for species of

  20. The braided single-stage protocol for quantum secure communication

    NASA Astrophysics Data System (ADS)

    Darunkar, Bhagyashri; Verma, Pramode K.

    2014-05-01

    This paper presents the concept and implementation of a Braided Single-stage Protocol for quantum secure communication. The braided single-stage protocol is a multi-photon tolerant secure protocol. This multi-photon tolerant protocol has been implemented in the laboratory using free-space optics technology. The proposed protocol capitalizes on strengths of the three-stage protocol and extends it with a new concept of braiding. This protocol overcomes the limitations associated with the three-stage protocol in the following ways: It uses the transmission channel only once as opposed to three times in the three-stage protocol, and it is invulnerable to man-in-the-middle attack. This paper also presents the error analysis resulting from the misalignment of the devices in the implementation. The experimental results validate the efficient use of transmission resources and improvement in the data transfer rate.

  1. OVERVIEW OF UIN/CEC LRTAP PROTOCOLS ON POPS AND HEAVY METALS

    EPA Science Inventory

    The purpose of this workshop was to review the current state-of-the-science for persistent organic pollutants and heavy metal compounds, especially additional developments since the conclusion of the negotiations of the Protocols on these compounds under the Convention on Long Ra...

  2. Standardized food images: A photographing protocol and image database.

    PubMed

    Charbonnier, Lisette; van Meer, Floor; van der Laan, Laura N; Viergever, Max A; Smeets, Paul A M

    2016-01-01

    The regulation of food intake has gained much research interest because of the current obesity epidemic. For research purposes, food images are a good and convenient alternative for real food because many dietary decisions are made based on the sight of foods. Food pictures are assumed to elicit anticipatory responses similar to real foods because of learned associations between visual food characteristics and post-ingestive consequences. In contemporary food science, a wide variety of images are used which introduces between-study variability and hampers comparison and meta-analysis of results. Therefore, we created an easy-to-use photographing protocol which enables researchers to generate high resolution food images appropriate for their study objective and population. In addition, we provide a high quality standardized picture set which was characterized in seven European countries. With the use of this photographing protocol a large number of food images were created. Of these images, 80 were selected based on their recognizability in Scotland, Greece and The Netherlands. We collected image characteristics such as liking, perceived calories and/or perceived healthiness ratings from 449 adults and 191 children. The majority of the foods were recognized and liked at all sites. The differences in liking ratings, perceived calories and perceived healthiness between sites were minimal. Furthermore, perceived caloric content and healthiness ratings correlated strongly (r ≥ 0.8) with actual caloric content in both adults and children. The photographing protocol as well as the images and the data are freely available for research use on http://nutritionalneuroscience.eu/. By providing the research community with standardized images and the tools to create their own, comparability between studies will be improved and a head-start is made for a world-wide standardized food image database.

  3. Microbial groundwater sampling protocol for fecal-rich environments.

    PubMed

    Harter, Thomas; Watanabe, Naoko; Li, Xunde; Atwill, Edward R; Samuels, William

    2014-09-01

    Inherently, confined animal farming operations (CAFOs) and other intense fecal-rich environments are potential sources of groundwater contamination by enteric pathogens. The ubiquity of microbial matter poses unique technical challenges in addition to economic constraints when sampling wells in such environments. In this paper, we evaluate a groundwater sampling protocol that relies on extended purging with a portable submersible stainless steel pump and Teflon(®) tubing as an alternative to equipment sterilization. The protocol allows for collecting a large number of samples quickly, relatively inexpensively, and under field conditions with limited access to capacity for sterilizing equipment. The protocol is tested on CAFO monitoring wells and considers three cross-contamination sources: equipment, wellbore, and ambient air. For the assessment, we use Enterococcus, a ubiquitous fecal indicator bacterium (FIB), in laboratory and field tests with spiked and blank samples, and in an extensive, multi-year field sampling campaign on 17 wells within 2 CAFOs. The assessment shows that extended purging can successfully control for equipment cross-contamination, but also controls for significant contamination of the well-head, within the well casing and within the immediate aquifer vicinity of the well-screen. Importantly, our tests further indicate that Enterococcus is frequently entrained in water samples when exposed to ambient air at a CAFO during sample collection. Wellbore and air contamination pose separate challenges in the design of groundwater monitoring strategies on CAFOs that are not addressed by equipment sterilization, but require adequate QA/QC procedures and can be addressed by the proposed sampling strategy.

  4. Microbial Groundwater Sampling Protocol for Fecal-Rich Environments

    PubMed Central

    Harter, Thomas; Watanabe, Naoko; Li, Xunde; Atwill, Edward R; Samuels, William

    2014-01-01

    Inherently, confined animal farming operations (CAFOs) and other intense fecal-rich environments are potential sources of groundwater contamination by enteric pathogens. The ubiquity of microbial matter poses unique technical challenges in addition to economic constraints when sampling wells in such environments. In this paper, we evaluate a groundwater sampling protocol that relies on extended purging with a portable submersible stainless steel pump and Teflon® tubing as an alternative to equipment sterilization. The protocol allows for collecting a large number of samples quickly, relatively inexpensively, and under field conditions with limited access to capacity for sterilizing equipment. The protocol is tested on CAFO monitoring wells and considers three cross-contamination sources: equipment, wellbore, and ambient air. For the assessment, we use Enterococcus, a ubiquitous fecal indicator bacterium (FIB), in laboratory and field tests with spiked and blank samples, and in an extensive, multi-year field sampling campaign on 17 wells within 2 CAFOs. The assessment shows that extended purging can successfully control for equipment cross-contamination, but also controls for significant contamination of the well-head, within the well casing and within the immediate aquifer vicinity of the well-screen. Importantly, our tests further indicate that Enterococcus is frequently entrained in water samples when exposed to ambient air at a CAFO during sample collection. Wellbore and air contamination pose separate challenges in the design of groundwater monitoring strategies on CAFOs that are not addressed by equipment sterilization, but require adequate QA/QC procedures and can be addressed by the proposed sampling strategy. PMID:24903186

  5. Microbial groundwater sampling protocol for fecal-rich environments.

    PubMed

    Harter, Thomas; Watanabe, Naoko; Li, Xunde; Atwill, Edward R; Samuels, William

    2014-09-01

    Inherently, confined animal farming operations (CAFOs) and other intense fecal-rich environments are potential sources of groundwater contamination by enteric pathogens. The ubiquity of microbial matter poses unique technical challenges in addition to economic constraints when sampling wells in such environments. In this paper, we evaluate a groundwater sampling protocol that relies on extended purging with a portable submersible stainless steel pump and Teflon(®) tubing as an alternative to equipment sterilization. The protocol allows for collecting a large number of samples quickly, relatively inexpensively, and under field conditions with limited access to capacity for sterilizing equipment. The protocol is tested on CAFO monitoring wells and considers three cross-contamination sources: equipment, wellbore, and ambient air. For the assessment, we use Enterococcus, a ubiquitous fecal indicator bacterium (FIB), in laboratory and field tests with spiked and blank samples, and in an extensive, multi-year field sampling campaign on 17 wells within 2 CAFOs. The assessment shows that extended purging can successfully control for equipment cross-contamination, but also controls for significant contamination of the well-head, within the well casing and within the immediate aquifer vicinity of the well-screen. Importantly, our tests further indicate that Enterococcus is frequently entrained in water samples when exposed to ambient air at a CAFO during sample collection. Wellbore and air contamination pose separate challenges in the design of groundwater monitoring strategies on CAFOs that are not addressed by equipment sterilization, but require adequate QA/QC procedures and can be addressed by the proposed sampling strategy. PMID:24903186

  6. Determination of the optimal therapeutic protocols in cancer immunotherapy.

    PubMed

    Cappuccio, Antonio; Castiglione, Filippo; Piccoli, Benedetto

    2007-09-01

    Cancer immunotherapy aims at eliciting an immune system response against the tumor. However, it is often characterized by toxic side-effects. Limiting the tumor growth and, concurrently, avoiding the toxicity of a drug, is the problem of protocol design. We formulate this question as an optimization problem and derive an algorithm for its solution. Unlike the standard optimal control approach, the algorithm simulates impulse-like drug administrations. It relies on an exact computation of the gradient of the cost function with respect to any protocol by means of the variational equations, that can be solved in parallel with the system. In comparison with previous versions of this method [F. Castiglione, B. Piccoli, Optimal control in a model of dendritic cell transfection cancer immunotherapy, Bull. Math. Biol. 68 (2006) 255-274; B. Piccoli, F. Castiglione, Optimal vaccine scheduling in cancer immunotherapy, Physica A. 370 (2) (2007) 672-680], we optimize both the timing and the dosage of each administration and introduce a penalty term to avoid clustering of subsequent injections, a requirement consistent with the clinical practice. In addition, we implement the optimization scheme to simulate the case of multi-therapies. The procedure works for any ODE system describing the pharmacokinetics and pharmacodynamics of an arbitrary number of therapeutic agents. In this work, it was tested for a well known model of the tumor-immune system interaction [D. Kirschner, J.C. Panetta, Modeling immunotherapy of tumor-immune interaction, J. Math. Biol. 37 (1998) 235-252]. Exploring three immunotherapeutic scenarios (CTL therapy, IL-2 therapy and combined therapy), we display the stability and efficacy of the optimization method, obtaining protocols that are successful compromises between various clinical requirements.

  7. Mitigation of hurricane potential intensity by the Montreal Protocol

    NASA Astrophysics Data System (ADS)

    Camargo, S. J.; Polvani, L. M.; Garcia, R. R.

    2014-12-01

    In the last decade, it has become apparent that the regulation ofozone depleting substances (ODS) by the Montreal Protocol has hadprofound impacts on the climate system, affecting not only surfacetemperatures but also the atmospheric circulation and the entirehydrological cycle. In this study we demonstrate that he MontrealProtocol will also be very effective in mitigating the potentialintensity (PI) of hurricanes in the coming half century. We accomplish this by comparing the projections of a standard CMIP5RCP4.5 scenario to those of the so-called "World Avoided" scenario, inwhich ODS grow unabated in the absence of regulations. For thiscomparison, we use ouput from two 3-member ensembles of WholeAtmosphere Community Climate Model (WACCM), integrated between 2005and 2065. WACCM is the most comprehensive member of the CommunityEarth System Models (CESM), and includes interactive stratosphericchemistry, in addition to coupled land, ocean, and sea-ice components, In the World Avoided projections we find that the hurricane PI issubstantially larger that in the standard RCP4.5 case. Specifically,over the decade 2056-2065, the increase in PI is comparable to the onebetween RCP4.5 and RCP8.5 for the entire multi-model mean of the CMIP5models. Similar to what is projected by the CMIP5 models forincreasing CO2, in the World Avoided scenario the increase in hurricanPI is due to a combined increase in sea surface temperature and CAPE,and a decrease in the temperature in upper levels, near 70hPa. Our WACCM simulations indicate that the mitigating effect of theMontreal Protocol is highly significant: without ODSs regulations thePI would be twice as large as currently projected by the middle ofthis century.

  8. Hybrid protocol of remote implementations of quantum operations

    SciTech Connect

    Zhao Ningbo; Wang Anmin

    2007-12-15

    We propose a protocol of remote implementations of quantum operations by hybridizing bidirectional quantum-state teleportation (BQST) [Huelga et al., Phys. Rev. A 63, 042303 (2001)] and the Wang protocol [Wang, Phys. Rev. A 74, 032317 (2006)]. The protocol is available for remote implementations of quantum operations in the restricted sets specified in the paper. We also give a proof of the protocol and point out its optimization. As an extension, this hybrid protocol can be reduced to the BQST and Wang protocols.

  9. Improved protocols for protein and RNA isolation from three-dimensional collagen sandwich cultures of primary hepatocytes.

    PubMed

    Heidebrecht, F; Schulz, I; Keller, M; Behrens, S-E; Bader, A

    2009-10-01

    The sandwich culture is the most widely used long-term culture system for functional primary hepatocytes. Despite its advantages, the currently available protocols for protein and RNA extraction are either time-consuming or contain steps that may skewer the results. This paper describes improved protocols for RNA and protein extraction from sandwich cultures that are easy to perform, require short working time, and use no additional enzymatic reactions that could change the expression profile of the cells. The quality of the RNA is excellent, allowing also applications requiring high purity such as microarrays. In general, the protocols are suited for any cells in 3D collagen culture. PMID:19539596

  10. Incorporation of additives into polymers

    DOEpatents

    McCleskey, T. Mark; Yates, Matthew Z.

    2003-07-29

    There has been invented a method for incorporating additives into polymers comprising: (a) forming an aqueous or alcohol-based colloidal system of the polymer; (b) emulsifying the colloidal system with a compressed fluid; and (c) contacting the colloidal polymer with the additive in the presence of the compressed fluid. The colloidal polymer can be contacted with the additive by having the additive in the compressed fluid used for emulsification or by adding the additive to the colloidal system before or after emulsification with the compressed fluid. The invention process can be carried out either as a batch process or as a continuous on-line process.

  11. Improving security in the Fiber Distributed Data Interface (FDDI) protocol

    NASA Astrophysics Data System (ADS)

    Jones, Benjamin E.

    1992-09-01

    The arrival of high speed packet switched fiber optic LAN's has allowed local area design architectures to be used for larger metropolitan area network (MAN) implementations. The current LAN security mechanisms used in larger and faster fiber optic LAN's and MAN's are often inappropriate or unacceptable for use with emerging applications. The protocol of the Fiber Distributed Data Interface (FDDI) standard provides a natural means for message integrity and availability verification. However, privacy in FDDI is facilitated at higher layers through a generic LAN standard. This thesis proposes a modification to the FDDI protocol implemented at the medium access control (MAC) sublayer, which integrates a confidentiality mechanism for data transfer. The modification provides a simple comprehensive security package to meet the high performance needs of current and emerging applications. In the proposed modification, the inherent properties of the ring are exploited using a unique Central Key Translator to distribute initial session keys. A symmetric bit stream cipher based on modulo2 addition is used for encryption/decryption by the transmitting and receiving stations. Part of the plain text from transmitted message frames is used as feedback to generate new session keys.

  12. Establishing a standardized therapeutic testing protocol for spinal muscular atrophy.

    PubMed

    Tsai, Li-Kai; Tsai, Ming-Shung; Lin, Tzer-Bin; Hwu, Wuh-Liang; Li, Hung

    2006-11-01

    Several mice models have been created for spinal muscular atrophy (SMA); however, there is still no standard preclinical testing system for the disease. We previously generated type III-specific SMA model mice, which might be suitable for use as a preclinical therapeutic testing system for SMA. To establish such a system and test its applicability, we first created a testing protocol and then applied it as a means to investigate the use of valproic acid (VPA) as a possible treatment for SMA. These SMA mice revealed tail/ear/foot deformity, muscle atrophy, poorer motor performances, smaller compound muscle action potential and lower spinal motoneuron density at the age of 9 to 12 months in comparison with age-matched wild-type littermate mice. In addition, VPA attenuates motoneuron death, increases spinal SMN protein level and partially normalizes motor function in SMA mice. These results suggest that the testing protocol developed here is well suited for use as a standardized preclinical therapeutic testing system for SMA.

  13. MAC protocol for an ATM-based SuperPON

    NASA Astrophysics Data System (ADS)

    Angelopoulos, John D.; Koulouris, John; Fragoulopoulos, Stratos K.

    1996-11-01

    Developments in optical amplifiers and the tendency towards fewer and larger switching stages made feasible and desirable the concept of SuperPONs with a range of 100km. Up to 15000 residential customers can share the SuperPON on a TDMA basis lowering the cost of access to B-ISDN services. Tree PONs require a MAC protocol to arbitrate the access to upstream slots among the competing customer ATM cells in a dynamic and efficient way. The protocol presented in this work combines different access mechanisms according to service quality requirements. All bursty traffic is manipulated transparently using a reservation approach with closed loop control so as to handle the unpredictability of arrivals. In contrast, voice, N-ISDN and other delay sensitive services are provided with unsolicited access permits. In addition, composite cells offered quasi- synchronous permits are used to support STM legacy traffic without echo-cancellers. So, ABR traffic which is delay tolerant and more cost sensitive, can and should be concentrated with full exploitation of multiplexing gain prospects. The permit distribution algorithm focuses on cell spacing, control of CDV, almost jitter free access for synchronous traffic and efficiency for ABR traffic.

  14. Distilled water challenges in asthmatic children. Comparison of different protocols.

    PubMed

    Eichler, I; Götz, M; Zarkovic, J; Köfinger, A

    1992-09-01

    Inhalation of ultrasonically nebulized distilled water (UNDW) appears a promising candidate for routine challenge testing in bronchial asthma. We have compared two different methods of application of UNDW in 12 asthmatic children with a positive response to methacholine provocation (MCh), in an attempt to increase UNDW sensitivity and to establish standard testing protocols. In addition, results from UNDW challenges were compared to responses to inhalation of jet-nebulized distilled water (JNDW) and cold air (CACh). Compared to MCh, the sensitivity of continuously or intermittently (iUNDW) inhaled UNDW was 67 percent or 75 percent, respectively, when a positive response was defined by a greater than or equal to 20 percent fall in FEV1, but was higher when definition of a positive response was based on results from flow volume curves. Sensitivity of continuous or intermittent inhalation of JNDW was lower than for UNDW. The UNDW inhalations were better tolerated than CACh. Following stepwise iUNDW challenge, there was a clear reaction plateau for all variables measured. Results indicate that testing protocols with iUNDW inhalations over 6 to 10 min (corresponding to 7 to 11 ml water inhalation) yield the maximum sensitivity attainable with UNDW challenges, and require a minimum of patient and investigator effort.

  15. Simple algorithm for improved security in the FDDI protocol

    NASA Astrophysics Data System (ADS)

    Lundy, G. M.; Jones, Benjamin

    1993-02-01

    We propose a modification to the Fiber Distributed Data Interface (FDDI) protocol based on a simple algorithm which will improve confidential communication capability. This proposed modification provides a simple and reliable system which exploits some of the inherent security properties in a fiber optic ring network. This method differs from conventional methods in that end to end encryption can be facilitated at the media access control sublayer of the data link layer in the OSI network model. Our method is based on a variation of the bit stream cipher method. The transmitting station takes the intended confidential message and uses a simple modulo two addition operation against an initialization vector. The encrypted message is virtually unbreakable without the initialization vector. None of the stations on the ring will have access to both the encrypted message and the initialization vector except the transmitting and receiving stations. The generation of the initialization vector is unique for each confidential transmission and thus provides a unique approach to the key distribution problem. The FDDI protocol is of particular interest to the military in terms of LAN/MAN implementations. Both the Army and the Navy are considering the standard as the basis for future network systems. A simple and reliable security mechanism with the potential to support realtime communications is a necessary consideration in the implementation of these systems. The proposed method offers several advantages over traditional methods in terms of speed, reliability, and standardization.

  16. Experimental protocol for packaging and encrypting multiple data

    NASA Astrophysics Data System (ADS)

    Fredy Barrera, John; Trejos, Sorayda; Tebaldi, Myrian; Torroba, Roberto

    2013-05-01

    We present a novel single optical packaging and encryption (SOPE) procedure for multiple inputs. This procedure is based on a merging of a 2f scheme with a digital holographic technique to achieve efficient handling of multiple data. Through the 2f system with a random phase mask attached in its input plane, and the holographic technique, we obtain each processed input. A posteriori filtering and repositioning protocol on each hologram followed by an addition of all processed data, allows storing these data to form a single package. The final package is digitally multiplied by a second random phase mask acting as an encryption mask. In this way, the final user receives only one encrypted information unit and a single key, instead of a conventional multiple-image collecting method and several keys. Processing of individual images is cast into an optimization problem. The proposed optimization aims to simplify the handling and recovery of images while packing all of them into a single unit. The decoding process does not have the usual cross-talk or noise problems involved in other methods, as filtering and repositioning precedes the encryption step. All data are recovered in just one step at the same time by applying a simple Fourier transform operation and the decoding key. The proposed protocol takes advantage of optical processing and the versatility of the digital format. Experiments have been conducted using a Mach-Zehnder interferometer. An application is subsequently demonstrated to illustrate the feasibility of the SOPE procedure.

  17. Pelvic Muscle Rehabilitation: A Standardized Protocol for Pelvic Floor Dysfunction

    PubMed Central

    Pedraza, Rodrigo; Nieto, Javier; Ibarra, Sergio; Haas, Eric M.

    2014-01-01

    Introduction. Pelvic floor dysfunction syndromes present with voiding, sexual, and anorectal disturbances, which may be associated with one another, resulting in complex presentation. Thus, an integrated diagnosis and management approach may be required. Pelvic muscle rehabilitation (PMR) is a noninvasive modality involving cognitive reeducation, modification, and retraining of the pelvic floor and associated musculature. We describe our standardized PMR protocol for the management of pelvic floor dysfunction syndromes. Pelvic Muscle Rehabilitation Program. The diagnostic assessment includes electromyography and manometry analyzed in 4 phases: (1) initial baseline phase; (2) rapid contraction phase; (3) tonic contraction and endurance phase; and (4) late baseline phase. This evaluation is performed at the onset of every session. PMR management consists of 6 possible therapeutic modalities, employed depending on the diagnostic evaluation: (1) down-training; (2) accessory muscle isolation; (3) discrimination training; (4) muscle strengthening; (5) endurance training; and (6) electrical stimulation. Eight to ten sessions are performed at one-week intervals with integration of home exercises and lifestyle modifications. Conclusions. The PMR protocol offers a standardized approach to diagnose and manage pelvic floor dysfunction syndromes with potential advantages over traditional biofeedback, involving additional interventions and a continuous pelvic floor assessment with management modifications over the clinical course. PMID:25006337

  18. [Patch-testing methods: additional specialised or additional series].

    PubMed

    Cleenewerck, M-B

    2009-01-01

    The tests in the European standard battery must occasionally be supplemented by specialised or additional batteries, particularly where the contact allergy is thought to be of occupational origin. These additional batteries cover all allergens associated with various professional activities (hairdressing, baking, dentistry, printing, etc.) and with different classes of materials and chemical products (glue, plastic, rubber...). These additional tests may also include personal items used by patients on a daily basis such as cosmetics, shoes, plants, textiles and so on.

  19. Additive manufacturing of optical components

    NASA Astrophysics Data System (ADS)

    Heinrich, Andreas; Rank, Manuel; Maillard, Philippe; Suckow, Anne; Bauckhage, Yannick; Rößler, Patrick; Lang, Johannes; Shariff, Fatin; Pekrul, Sven

    2016-08-01

    The development of additive manufacturing methods has enlarged rapidly in recent years. Thereby, the work mainly focuses on the realization of mechanical components, but the additive manufacturing technology offers a high potential in the field of optics as well. Owing to new design possibilities, completely new solutions are possible. This article briefly reviews and compares the most important additive manufacturing methods for polymer optics. Additionally, it points out the characteristics of additive manufactured polymer optics. Thereby, surface quality is of crucial importance. In order to improve it, appropriate post-processing steps are necessary (e.g. robot polishing or coating), which will be discussed. An essential part of this paper deals with various additive manufactured optical components and their use, especially in optical systems for shape metrology (e.g. borehole sensor, tilt sensor, freeform surface sensor, fisheye lens). The examples should demonstrate the potentials and limitations of optical components produced by additive manufacturing.

  20. Development of Next Generation Energy Audit Protocols for the Rapid and Advanced Analysis of Building Energy Use

    NASA Astrophysics Data System (ADS)

    Hartley, Christopher Ahlvin

    Current building energy auditing techniques are outdated and lack targeted, actionable information. These analyses only use one year's worth of monthly electricity and gas bills to define energy conservation and efficiency measures. These limited data sets cannot provide robust, directed energy reduction recommendations. The need is apparent for an overhaul of existing energy audit protocols to utilize all data that is available from the building's utility provider, installed energy management system (EMS), and sub-metering devices. This thesis analyzed the current state-of-the-art in energy audits, generated a next generation energy audit protocol, and conducted both audits types on four case study buildings to find out what additional information can be obtained from additional data sources and increased data gathering resolutions. Energy data from each case study building were collected using a variety of means including utility meters, whole building energy meters, EMS systems, and sub-metering devices. In addition to conducting an energy analysis for each case study building using the current and next generation energy audit protocols, two building energy models were created using the programs eQuest and EnergyPlus. The current and next generation energy audit protocol results were compared to one another upon completion. The results show that using the current audit protocols, only variations in season are apparent. Results from the developed next generation energy audit protocols show that in addition to seasonal variations, building heating, ventilation and air conditioning (HVAC) schedules, occupancy schedules, baseline and peak energy demand levels, and malfunctioning equipment can be found. This new protocol may also be used to quickly generate accurate building models because of the increased resolution that yields scheduling information. The developed next generation energy auditing protocol is scalable and can work for many building types across the

  1. Protocol Directed Patient Care using a Computer

    PubMed Central

    Blum, B.; Lenhard, R.; McColligan, E.

    1980-01-01

    The Johns Hopkins Oncology Center has developed a clinical information system which assists in the care of the 2,000 patients currently under treatment at the Center. The system maintains a data base containing a summary diagnostic and treatment history plus complete tabulations of laboratory results, therapies, and other clinical findings. These data are organized and displayed in formats which aid decision-making. For the past year the Center has been working with an extension to the data system which produces daily care plans for each inpatient and outpatient treated at the Center. These plans are a function of the disease, treatment protocol, and current clinical status of each patient. This paper describes the objectives, organization, and experience to date with the use of computer generated plans for protocol directed patient care.

  2. An Evaluation of UDP Transport Protocols

    SciTech Connect

    Carter, S

    2004-12-21

    Although the speed of LAN and WAN networking is growing at an exponential rate, the applications that use those networks have not followed suit. With fiber optic interconnects, gigahertz processor speeds, and 10 gigabit per second network interface cards, hardware does not seem to be the limiting factor. It is becoming increasingly obvious that the protocols that are the basis of networking today are ill-suited to a new generation of networking technology. For this reason, Oak Ridge National Laboratory is particularly interested in improving bulk transfers over high-bandwidth, high-latency networks because of its involvement in storage and in the transfer of data for cutting-edge scientific applications. This report summarizes our evaluation of a new group of protocols specifically designed to get more useful bandwidth from today's high speed, wide area networks.

  3. UV Impacts Avoided by the Montreal Protocol

    NASA Technical Reports Server (NTRS)

    Newman, Paul; McKenzie, Richard

    2010-01-01

    Temporal and geographical variabilities in the future "World Expected" UV environment are compared with the "World Avoided", which would have occurred without the Montreal Protocol on protection of the ozone layer and its subsequent amendments and adjustments. Based on calculations of clear-sky UV irradiances, the effects of the Montreal Protocol have been hugely beneficial to avoid the health risks, such as skin cancer, which are associated with high UV, while there is only a small increase in health risks, such as vitamin D deficiency, that are associated with low UV. However, interactions with climate change may lead to changes in cloud and albedo, and possibly behavioural changes which could also be important.

  4. Da Vinci robot emergency undocking protocol.

    PubMed

    O'Sullivan, O E; O'Sullivan, S; Hewitt, M; O'Reilly, B A

    2016-09-01

    The role of robot-assisted surgery across gynaecology is evolving with increasing numbers of procedures being undertaken with varying degrees of complexity. While the risk of conversion is low at approximately 1 %, the reasons for conversion are variable. These range from technical issues with the robot, surgical complications such as haemorrhage and anaesthetics issues such as an inability to ventilate the patient adequately. While many conversions to open or laparoscopic approach are not due to life-threatening indications, it is important that the theatre staff are aware of the indication and can perform an emergency undocking as effectively, efficiently and safely as possible when the need arises. Unfortunately, there is a paucity of the literature available outlining such protocols. For this reason, we developed an emergency undocking protocol clearly outlining the role of each theatre staff member and the need for clear concise communication. PMID:27126584

  5. Multipass Steering Protocols at Jefferson Lab

    SciTech Connect

    Ryan Bodenstein; Michael Tiefenback

    2007-06-22

    The CEBAF recirculating accelerator consists of two CW superconducting RF linacs, through which an electron beam is accelerated for up to 5 passes. Focusing and steering elements affect each pass differently, requiring a multipass steering protocol to correct the orbits. Perturbations include lens misalignments (including long-term ground motion), BPM offsets, and focusing and steering from RF fields inside the cavities. A previous treatment of this problem assumed all perturbations were localized at the quadrupoles and the absence of x-y coupling. Having analyzed the problem and characterized the solutions, we developed an empirical iterative protocol to compare against previous results in the presence of skew fields and cross-plane coupling. We plan to characterize static and acceleration-dependent components of the beam line perturbations to allow systematic and rapid configuration of the accelerator at different linac energy gains.

  6. Staining protocol for organotypic hippocampal slice cultures.

    PubMed

    Gogolla, Nadine; Galimberti, Ivan; DePaola, Vincenzo; Caroni, Pico

    2006-01-01

    This protocol details a method to immunostain organotypic slice cultures from mouse hippocampus. The cultures are based on the interface method, which does not require special equipment, is easy to execute and yields slice cultures that can be imaged repeatedly, from the time of isolation at postnatal day 6-9 up to 6 months in vitro. The preserved tissue architecture facilitates the analysis of defined hippocampal synapses, cells and entire projections. Time-lapse imaging is based on transgenes expressed in the mice or on constructs introduced through transfection or viral vectors; it can reveal processes that develop over periods ranging from seconds to months. Subsequent to imaging, the slices can be processed for immunocytochemistry to collect further information about the imaged structures. This protocol can be completed in 3 d.

  7. UV impacts avoided by the Montreal Protocol.

    PubMed

    Newman, Paul A; McKenzie, Richard

    2011-07-01

    Temporal and geographical variabilities in the future "world expected" UV environment are compared with the "world avoided", which would have occurred without the Montreal Protocol on Substances That Deplete the Ozone Layer and its subsequent amendments and adjustments. Based on calculations of clear-sky UV irradiances, the effects of the Montreal Protocol have been hugely beneficial to avoid the health risks, such as skin cancer, which are associated with high UV, while there is only a small increase in health risks, such as vitamin D deficiency, that are associated with low UV. However, interactions with climate change may lead to changes in cloud and albedo, and possibly behavioural changes that could also be important.

  8. Remote Memory Access Protocol Target Node Intellectual Property

    NASA Technical Reports Server (NTRS)

    Haddad, Omar

    2013-01-01

    The MagnetoSpheric Multiscale (MMS) mission had a requirement to use the Remote Memory Access Protocol (RMAP) over its SpaceWire network. At the time, no known intellectual property (IP) cores were available for purchase. Additionally, MMS preferred to implement the RMAP functionality with control over the low-level details of the design. For example, not all the RMAP standard functionality was needed, and it was desired to implement only the portions of the RMAP protocol that were needed. RMAP functionality had been previously implemented in commercial off-the-shelf (COTS) products, but the IP core was not available for purchase. The RMAP Target IP core is a VHDL (VHSIC Hardware Description Language description of a digital logic design suitable for implementation in an FPGA (field-programmable gate array) or ASIC (application-specific integrated circuit) that parses SpaceWire packets that conform to the RMAP standard. The RMAP packet protocol allows a network host to access and control a target device using address mapping. This capability allows SpaceWire devices to be managed in a standardized way that simplifies the hardware design of the device, as well as the development of the software that controls the device. The RMAP Target IP core has some features that are unique and not specified in the RMAP standard. One such feature is the ability to automatically abort transactions if the back-end logic does not respond to read/write requests within a predefined time. When a request times out, the RMAP Target IP core automatically retracts the request and returns a command response with an appropriate status in the response packet s header. Another such feature is the ability to control the SpaceWire node or router using RMAP transactions in the extended address range. This allows the SpaceWire network host to manage the SpaceWire network elements using RMAP packets, which reduces the number of protocols that the network host needs to support.

  9. Montreal Protocol Benefits simulated with CCM SOCOL

    NASA Astrophysics Data System (ADS)

    Egorova, T.; Rozanov, E.; Gröbner, J.; Hauser, M.; Schmutz, W.

    2013-04-01

    Ozone depletion is caused by the anthropogenic increase of halogen-containing species in the atmosphere, which results in the enhancement of the concentration of reactive chlorine and bromine in the stratosphere. To reduce the influence of anthropogenic ozone-depleting substances (ODS), the Montreal Protocol was agreed by Governments in 1987, with several Amendments and Adjustments adopted later. In order to assess the benefits of the Montreal Protocol and its Amendments and Adjustments (MPA) on ozone and UV radiation, two different runs of the chemistry-climate model (CCM) SOCOL have been carried out. The first run was driven by the emission of ozone depleting substances (ODS) prescribed according to the restrictions of the MPA. For the second run we allow the ODS to grow by 3% annually. We find that the MPA would have saved up to 80% of the global annual total ozone by the end of the 21st century. Our calculations also show substantial changes of the stratospheric circulation pattern as well as in surface temperature and precipitations that could occur in the world without MPA implementations. To illustrate the changes in UV radiation at the surface and to emphasise certain features, which can only be seen for some particular regions if the influence of the cloud cover changes is accounted for, we calculate geographical distribution of the erythemally weighted irradiance (Eery). For the no Montreal Protocol simulation Eery increases by factor of 4 to 16 between the 1970s and 2100. For the scenario including the Montreal Protocol it is found that UV radiation starts to decrease in 2000, with continuous decline of 5% to 10% at middle latitudes in the both Northern and Southern Hemispheres.

  10. Mars Sample Handling Protocol Workshop Series

    NASA Technical Reports Server (NTRS)

    Rummel, John D. (Editor); Race, Margaret S. (Editor); Acevedo, Sara (Technical Monitor)

    2000-01-01

    This document is the report resulting from the first workshop of the series on development of the criteria for a Mars sample handling protocol. Workshop 1 was held in Bethesda, Maryland on March 20-22, 2000. This report serves to document the proceedings of Workshop 1; it summarizes relevant background information, provides an overview of the deliberations to date, and helps frame issues that will need further attention or resolution in upcoming workshops. Specific recommendations are not part of this report.

  11. D-RATS 2011: RAFT Protocol Overview

    NASA Technical Reports Server (NTRS)

    Utz, Hans

    2011-01-01

    A brief overview presentation on the protocol used during the D-RATS2011 field test for file transfer from the field-test robots at Black Point Lava Flow AZ to Johnson Space Center, Houston TX over a simulated time-delay. The file transfer actually uses a commercial implementation of an open communications standard. The focus of the work lies on how to make the state of the distributed system observable.

  12. Protocol for mosquito rearing (A. gambiae).

    PubMed

    Das, Suchismita; Garver, Lindsey; Dimopoulos, George

    2007-01-01

    This protocol describes mosquito rearing in the insectary. The insectary rooms are maintained at 28 degrees C and approximately 80% humidity, with a 12 hr. day/night cycle. For this procedure, you'll need mosquito cages, 10% sterile sucrose solution, paper towels, beaker, whatman filter paper, glass feeders, human blood and serum, water bath, parafilm, distilled water, clean plastic trays, mosquito food (described below), mosquito net to cover the trays, vacuum, and a collection chamber to collect adults. PMID:18979019

  13. Building America House Simulation Protocols (Revised)

    SciTech Connect

    Hendron, R.; Engebrecht, C.

    2010-10-01

    The House Simulation Protocol document was developed to track and manage progress toward Building America's multi-year, average whole-building energy reduction research goals for new construction and existing homes, using a consistent analytical reference point. This report summarizes the guidelines for developing and reporting these analytical results in a consistent and meaningful manner for all home energy uses using standard operating conditions.

  14. Avian study protocols and wind energy development

    SciTech Connect

    Fisher, K.

    1995-12-01

    This paper identifies the need to develop and use standardized avian study protocols to determine avian impacts at new and existing wind energy facilities. This will allow data collected from various sites to be correlated for better understanding wind energy related avian impacts. Factors contributing to an increased interest in wind energy facilities by electric utilities include: (1) Increased demand for electricity;(2) increased constraints on traditional electrical generating facilities (i.e. hydroelectric and nuclear power plants);(3) improved wind turbine technology. During the 1980`s generous tax credits spawned the development of wind energy facilities, known as wind farms, in California. Commercial scale wind farm proposals are being actively considered in states across the country - Washington, Oregon, Wyoming, Wisconsin, Texas, and Vermont to name a few. From the wind farms in California the unexpected issue of avian impacts, especially to birds-of-prey, or raptor, surfaced and continues to plague the wind industry. However, most of the avian studies did not followed a standardized protocol or methodology and, therefore, data is unavailable to analyze and compare impacts at different sites or with differing technologies and configurations. Effective mitigation can not be designed and applied until these differences are understood. The Bonneville Power Administration is using comparable avian study protocols to collect data for two environmental impact statements being prepared for two separate wind farm proposals. Similar protocol will be required for any other avian impact analysis performed by the agency on proposed or existing wind farms. The knowledge gained from these studies should contribute to a better understanding of avian interactions with wind energy facilities and the identification of effective mitigation measures.

  15. The CCSDS Next Generation Space Data Link Protocol (NGSLP)

    NASA Technical Reports Server (NTRS)

    Kazz, Greg J.; Greenberg, Edward

    2014-01-01

    next leap in performance for space link communications. Field Programmable Gate Arrays (FPGAs) provide the capability to incorporate high performance forward error correcting codes implemented within software transponders providing improved performance in data transfer, ranging, link security, and time correlation. Given these synergistic technological breakthroughs, the time has come to take advantage of them in applying them to both on going (e.g., command, telemetry) and emerging (e.g., space link security, optical communication) space link applications. However one of the constraining factors within the Data Link Layer in realizing these performance gains is the lack of a generic transfer frame format and common supporting services amongst the existing CCSDS link layer protocols. Currently each of the four CCSDS link layer protocols (TM, TC, AOS, and Proximity-1) have unique formats and services which prohibits their reuse across the totality of all space link applications of CCSDS member space agencies. For example, Mars missions. These missions implement their proximity data link layer using the Proximity-1 frame format and the services it supports but is still required to support the direct from Earth (TC) protocols and the Direct To Earth (AOS/TM) protocols. The prime purpose of this paper, is to describe a new general purpose CCSDS Data Link layer protocol, the NGSLP that will provide the required services along with a common transfer frame format for all the CCSDS space links (ground to/from space and space to space links) targeted for emerging missions after a CCSDS agency-wide coordinated date. This paper will also describe related options that can be included for the Coding and Synchronization sub-layer of the Data Link layer to extend the capacities of the link and additionally provide an independence of the transfer frame sub-layer from the coding sublayer. This feature will provide missions the option of running either the currently performed

  16. An improved pyrite pretreatment protocol for kinetic and isotopic studies

    NASA Astrophysics Data System (ADS)

    Mirzoyan, Natella; Kamyshny, Alexey; Halevy, Itay

    2014-05-01

    , and was capable of removing virtually all S0 from the pyrite grains. As pyrite oxidation and dissolution processes are surface-dependent, and even the slightest coating by Fe2+ or sulfide oxidation products can sharply decrease pyrite reactivity, the improved removal of S0 prevents such decreases and allows clearer insights into pyrite reaction mechanisms to be gained from experimental studies. In addition to S0 removal, the suggested method was shown not to introduce any biases in the particle size distribution. The main difference observed between the two protocols is the removal of larger amounts of surface-attached fine particles in the proposed method along with S0. This also removes a potential bias, associated with the surface area of pyrite available for chemical reaction. The suggested pyrite pretreatment protocol is more efficient in removal of S0 contamination from pyrite grains and provides multiple advantages for both kinetic and isotopic investigations of pyrite transformations under various environmental conditions.

  17. Protocols for Authorized Release of Concrete

    SciTech Connect

    Smith, Agatha Marie; Meservey, Richard Harlan; Chen, S.Y.; Powell, James Edward; PArker, F.

    2000-06-01

    Much of the clean or slightly contaminated concrete from Decontamination and Decommissioning (D&D) activities could be re-used. Currently, there is no standardized approach, or protocol, for managing the disposition of such materials. Namely, all potential disposition options for concrete, including authorized release for re-use, are generally not fully evaluated in D&D projects, so large quantities have been unduly disposed of as low-level radioactive waste. As a result, costs of D&D have become prohibitively high, hindering expedient cleanup of surplus facilities. The ability to evaluate and implement the option of authorized release of concrete from demolition would result in significant cost savings, while maintaining protection of environmental health and safety, across the Department of Energy (DOE) complex. The Idaho National Engineering and Environmental Laboratory (INEEL), Argonne National Laboratory East (ANL-E), and Vanderbilt University have teamed to develop a protocol for the authorized release of concrete, based on the existing DOE guidance of Order 5400.5, that applies across the DOE complex. The protocol will provide a streamlined method for assessing risks and costs, and reaching optimal disposal options, including re-use of the concrete within the DOE system.

  18. Analysis of Security Protocols for Mobile Healthcare.

    PubMed

    Wazid, Mohammad; Zeadally, Sherali; Das, Ashok Kumar; Odelu, Vanga

    2016-11-01

    Mobile Healthcare (mHealth) continues to improve because of significant improvements and the decreasing costs of Information Communication Technologies (ICTs). mHealth is a medical and public health practice, which is supported by mobile devices (for example, smartphones) and, patient monitoring devices (for example, various types of wearable sensors, etc.). An mHealth system enables healthcare experts and professionals to have ubiquitous access to a patient's health data along with providing any ongoing medical treatment at any time, any place, and from any device. It also helps the patient requiring continuous medical monitoring to stay in touch with the appropriate medical staff and healthcare experts remotely. Thus, mHealth has become a major driving force in improving the health of citizens today. First, we discuss the security requirements, issues and threats to the mHealth system. We then present a taxonomy of recently proposed security protocols for mHealth system based on features supported and possible attacks, computation cost and communication cost. Our detailed taxonomy demonstrates the strength and weaknesses of recently proposed security protocols for the mHealth system. Finally, we identify some of the challenges in the area of security protocols for mHealth systems that still need to be addressed in the future to enable cost-effective, secure and robust mHealth systems.

  19. Analysis of Security Protocols for Mobile Healthcare.

    PubMed

    Wazid, Mohammad; Zeadally, Sherali; Das, Ashok Kumar; Odelu, Vanga

    2016-11-01

    Mobile Healthcare (mHealth) continues to improve because of significant improvements and the decreasing costs of Information Communication Technologies (ICTs). mHealth is a medical and public health practice, which is supported by mobile devices (for example, smartphones) and, patient monitoring devices (for example, various types of wearable sensors, etc.). An mHealth system enables healthcare experts and professionals to have ubiquitous access to a patient's health data along with providing any ongoing medical treatment at any time, any place, and from any device. It also helps the patient requiring continuous medical monitoring to stay in touch with the appropriate medical staff and healthcare experts remotely. Thus, mHealth has become a major driving force in improving the health of citizens today. First, we discuss the security requirements, issues and threats to the mHealth system. We then present a taxonomy of recently proposed security protocols for mHealth system based on features supported and possible attacks, computation cost and communication cost. Our detailed taxonomy demonstrates the strength and weaknesses of recently proposed security protocols for the mHealth system. Finally, we identify some of the challenges in the area of security protocols for mHealth systems that still need to be addressed in the future to enable cost-effective, secure and robust mHealth systems. PMID:27640159

  20. 21 CFR 814.19 - Product development protocol (PDP).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.19 Product development protocol (PDP). A class III device for which a product development protocol has been declared completed by FDA...

  1. 21 CFR 814.19 - Product development protocol (PDP).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.19 Product development protocol (PDP). A class III device for which a product development protocol has been declared completed by FDA...

  2. 21 CFR 814.19 - Product development protocol (PDP).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.19 Product development protocol (PDP). A class III device for which a product development protocol has been declared completed by FDA...

  3. SPIRIT 2013 Statement: defining standard protocol items for clinical trials.

    PubMed

    Chan, An-Wen; Tetzlaff, Jennifer M; Altman, Douglas G; Laupacis, Andreas; Gøtzsche, Peter C; Krle A-Jerić, Karmela; Hrobjartsson, Asbjørn; Mann, Howard; Dickersin, Kay; Berlin, Jesse A; Dore, Caroline J; Parulekar, Wendy R; Summerskill, William S M; Groves, Trish; Schulz, Kenneth F; Sox, Harold C; Rockhold, Frank W; Rennie, Drummond; Moher, David

    2015-12-01

    The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol. The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. The checklist recommends a full description of what is planned; it does not prescribe how to design or conduct a trial. By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. Adherence to SPIRIT would also enhance the transparency and completeness of trial protocols for the benefit of investigators, trial participants, patients, sponsors, funders, research ethics committees or institutional review boards, peer reviewers, journals, trial registries, policymakers, regulators, and other key stakeholders. PMID:27440100

  4. METHODS AND ANALYSES FOR IMPLEMENTING NATURAL ATTENUATION PROTOCOLS

    EPA Science Inventory

    Technical protocols for evaluating natural attenuation at petroleum hydrocarbon and chlorinated solvent contaminated sites specify the analysis of electron acceptors and metabolic by-products for identifying and quantifying natural attenuation processes. However, these protocols ...

  5. 21 CFR 814.19 - Product development protocol (PDP).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.19 Product development protocol (PDP). A class III device for which a product development protocol has been declared completed by FDA...

  6. Programmed electrical stimulation of the ventricle: an efficient, sensitive, and specific protocol.

    PubMed

    Fisher, J D; Kim, S G; Ferrick, K J; Artoul, S G; Fink, D; Roth, J A; Johnston, D R; Williams, H R

    1992-04-01

    A relatively simple and efficient ventricular programmed electrical stimulation (PES) protocol was developed, capable of achieving high degrees of sensitivity and specificity. In a series of 481 subjects, 1, 2, and 3 extrastimuli (ES) were used successively during sinus rhythm and ventricular pacing at two drive cycle lengths, at one or more ventricular sites, together with rapid ventricular pacing, and other maneuvers such as isoproterenol infusion. Three ES were used immediately after two ES at each drive rate, rather than returning after completion of the protocol with two ES. Using the protocol, appropriate arrhythmias could be induced in 88% of all patients with ventricular fibrillation, 84% of all patients with sustained ventricular tachycardia (91% with underlying coronary disease), and 58% of patients with severe nonsustained ventricular tachycardia. There were significant differences in inducibility between patients whose ventricular arrhythmias were due to coronary artery disease and other causes. In contrast, sustained ventricular arrhythmias (all ventricular fibrillation) could be induced in only 5% of a control group of control patients, for a specificity of 95%. The protocol described is simpler and more efficient than those that use exhaustive testing of two ES before going to three ES. Three ES during sinus rhythm proved to be the most productive step, with a higher yield ratio (true: false-positives) than two ES or three ES during pacing, especially at faster rates. Greater efficiency is also achieved by leaving the timing of an extrastimulus just beyond its effective refractory period when an additional extrastimulus is to be added, compared to protocols in which the extrastimulus is moved later in the cycle and then decremented in tandem with the additional extrastimulus. Coupling intervals less than 200 msec produced some false-positives, but fewer overall than intervals greater than or equal to 200 msec, and with yield ratios comparable to

  7. A Model Based Security Testing Method for Protocol Implementation

    PubMed Central

    Fu, Yu Long; Xin, Xiao Long

    2014-01-01

    The security of protocol implementation is important and hard to be verified. Since the penetration testing is usually based on the experience of the security tester and the specific protocol specifications, a formal and automatic verification method is always required. In this paper, we propose an extended model of IOLTS to describe the legal roles and intruders of security protocol implementations, and then combine them together to generate the suitable test cases to verify the security of protocol implementation. PMID:25105163

  8. Study on the conversion and test of protocols

    NASA Astrophysics Data System (ADS)

    Choi, Y.

    1984-06-01

    The conversion of protocols nonadapted to the open systems interconnection (OSI) architecture into compatibility with the OSI system and the test of the equipment for converting protocols are studied. Specification and validation of protocols are reviewed. The test of the X-21 procedure and the test of the signal management equipment, parts of the Telecom project, are analyzed. A specification method based on extended finite state machines is developed. A test system for protocol conversion equipment is described.

  9. Implementation of a Multidisciplinary Bleeding and Transfusion Protocol Significantly Decreases Perioperative Blood Product Utilization and Improves Some Bleeding Outcomes

    PubMed Central

    Timpa, Joseph G.; O’Meara, L. Carlisle; Goldberg, Kellen G.; Phillips, Jay P.; Crawford, Jack H.; Jackson, Kimberly W.; Alten, Jeffrey A.

    2016-01-01

    Abstract: Perioperative transfusion of blood products is associated with increased morbidity and mortality after pediatric cardiac surgery. We report the results of a quality improvement project aimed at decreasing perioperative blood product administration and bleeding after pediatric cardiopulmonary bypass (CPB) surgery. A multidisciplinary team evaluated baseline data from 99 consecutive CPB patients, focusing on the variability in transfusion management and bleeding outcomes, to create a standardized bleeding and transfusion management protocol. A total of 62 subsequent patients were evaluated after implementation of the protocol: 17 with single pass hemoconcentrated (SPHC) blood transfusion and 45 with modified ultrafiltration (MUF). Implementation of the protocol with SPHC blood led to significant decrease in transfusion of every blood product in the cardiovascular operating room and first 6 hours in cardiovascular intensive care unit ([CVICU] p < .05). Addition of MUF to the protocol led to further decrease in transfusion of all blood products compared to preprotocol. Patients <2 months old had 49% decrease in total blood product administration: 155 mL/kg preprotocol, 117 mL/kg protocol plus SPHC, and 79 mL/kg protocol plus MUF (p < .01). There were significant decreases in postoperative bleeding in the first hour after CVICU admission: 6 mL/kg preprotocol, 3.8 mL/kg protocol plus SPHC, and 2 mL/kg protocol plusMUF (p = .02). There was also significantly decreased incidence of severe postoperative bleeding (>10 mL/kg) in the first CVICU hour for protocol plus MUF patients (p < .01). Implementation of a multidisciplinary bleeding and transfusion protocol significantly decreases perioperative blood product transfusion and improves some bleeding outcomes. PMID:27134303

  10. Comparison of two isometric handgrip protocols on sympathetic arousal in women

    PubMed Central

    Nielsen, Shawn E.; Mather, Mara

    2015-01-01

    Isometric handgrip is commonly used in stress research because the task reliably increases sympathetic arousal. Various handgrip protocols have been used; they vary in handgrip strength, duration of grip, and the number of cycles of handgrip and rest. However, most protocols require the calibration of a maximum voluntary contraction (MVC) prior to the handgrip task, which is not always convenient (i.e., in a functional magnetic resonance imaging study). Here, we wanted to test whether two handgrip protocols with different strength, duration and cycle protocols would reliably elicit sympathetic arousal in the absence of calibrating an MVC. Sixty-two healthy naturally cycling women and women on hormonal contraception participated in one of the two isometric handgrip protocols using a hand therapy ball of medium resistance. Women completed one of the following handgrip protocols: 1) 30% of a perceived maximum voluntary contraction for 3 minutes or 2) 3 cycles of maximum voluntary contraction for 18 seconds with one minute rest in between. All handgrip blocks were counterbalanced with a control condition. Sympathetic arousal was measured throughout the session via pupil diameter changes and salivary alpha-amylase. Results indicate that in the absence of calibrating an MVC, the handgrip tasks elicited different changes in sympathetic arousal. Pupil dilation responses increased significantly in the handgrip versus control blocks only in participants in the 18-s protocol. Additionally, more participants exhibited a salivary alpha-amylase response to the handgrip block in the 18-s condition compared to the 3-min condition. Thus, these results suggest that neuroimaging and behavioral studies with isometric handgrip should be able to successfully induce sympathetic nervous activity with the 18-s paradigm, regardless of the handgrip device and the ability to calibrate an MVC. PMID:25637170

  11. A Protocol for the Secure Linking of Registries for HPV Surveillance

    PubMed Central

    El Emam, Khaled; Samet, Saeed; Hu, Jun; Peyton, Liam; Earle, Craig; Jayaraman, Gayatri C.; Wong, Tom; Kantarcioglu, Murat; Dankar, Fida; Essex, Aleksander

    2012-01-01

    Introduction In order to monitor the effectiveness of HPV vaccination in Canada the linkage of multiple data registries may be required. These registries may not always be managed by the same organization and, furthermore, privacy legislation or practices may restrict any data linkages of records that can actually be done among registries. The objective of this study was to develop a secure protocol for linking data from different registries and to allow on-going monitoring of HPV vaccine effectiveness. Methods A secure linking protocol, using commutative hash functions and secure multi-party computation techniques was developed. This protocol allows for the exact matching of records among registries and the computation of statistics on the linked data while meeting five practical requirements to ensure patient confidentiality and privacy. The statistics considered were: odds ratio and its confidence interval, chi-square test, and relative risk and its confidence interval. Additional statistics on contingency tables, such as other measures of association, can be added using the same principles presented. The computation time performance of this protocol was evaluated. Results The protocol has acceptable computation time and scales linearly with the size of the data set and the size of the contingency table. The worse case computation time for up to 100,000 patients returned by each query and a 16 cell contingency table is less than 4 hours for basic statistics, and the best case is under 3 hours. Discussion A computationally practical protocol for the secure linking of data from multiple registries has been demonstrated in the context of HPV vaccine initiative impact assessment. The basic protocol can be generalized to the surveillance of other conditions, diseases, or vaccination programs. PMID:22768321

  12. The IMPEx Protocol - building bridges between scientific databases and online tools

    NASA Astrophysics Data System (ADS)

    Al-Ubaidi, T.; Khodachenko, M. L.; Kallio, E. J.; Génot, V.; Modolo, R.; Hess, S.; Schmidt, W.; Scherf, M.; Topf, F.; Alexeev, I. I.; Gangloff, M.; Budnik, E.; Bouchemit, M.; Renard, B.; Bourrel, N.; Penou, E.; André, N.; Belenkaya, E. S.

    2014-04-01

    The FP7-SPACE project IMPEx (http://impex-fp7.oeaw.ac.at) was established as a result of scientific collaboration between research teams from Austria, Finland, France, and Russia, working on the integration of a set of data mining, analysis and modeling tools in the field of space plasma and planetary physics. The primary goal of the project is to bridge the gap between spacecraft measurements and up-to-date computational models of planetary environments, enabling their joint operation for a better understanding of related physical phenomena. The IMPEx Protocol constitutes one of the cornerstones of the integration effort. While the IMPEx Data Model assures that the information exchanged can be 'understood' and hence processed by every participating tool or database system, the protocol provides the means to leverage specific functionalities of the respective host system in conjunction with the data provided. Examples thereof would be services for calculating field lines and particle trajectories, on-the-fly modeling runs with specific parameters and so forth. Additionally there are also utility methods available that allow to e.g. access specific data files or support search interfaces by providing ranked lists of stored modeling runs for a given set of (upstream) parameters. The presentation offers an overview of the IMPEx protocol and addresses the motivation for some of the (technical)design decisions taken during the development process. Further the resulting SOAP based web service interface is discussed and individual services and their applications are addressed specifically. Last but not least the first available implementations of the protocol are presented and a brief overview of tools already leveraging the IMPEx protocol is provided. The presentation closes with an outlook on possible future applications as well as extensions of the IMPEx protocol, including information on how to get started when implementing the IMPEx protocol, in order to join the

  13. A secure distributed logistic regression protocol for the detection of rare adverse drug events

    PubMed Central

    El Emam, Khaled; Samet, Saeed; Arbuckle, Luk; Tamblyn, Robyn; Earle, Craig; Kantarcioglu, Murat

    2013-01-01

    Background There is limited capacity to assess the comparative risks of medications after they enter the market. For rare adverse events, the pooling of data from multiple sources is necessary to have the power and sufficient population heterogeneity to detect differences in safety and effectiveness in genetic, ethnic and clinically defined subpopulations. However, combining datasets from different data custodians or jurisdictions to perform an analysis on the pooled data creates significant privacy concerns that would need to be addressed. Existing protocols for addressing these concerns can result in reduced analysis accuracy and can allow sensitive information to leak. Objective To develop a secure distributed multi-party computation protocol for logistic regression that provides strong privacy guarantees. Methods We developed a secure distributed logistic regression protocol using a single analysis center with multiple sites providing data. A theoretical security analysis demonstrates that the protocol is robust to plausible collusion attacks and does not allow the parties to gain new information from the data that are exchanged among them. The computational performance and accuracy of the protocol were evaluated on simulated datasets. Results The computational performance scales linearly as the dataset sizes increase. The addition of sites results in an exponential growth in computation time. However, for up to five sites, the time is still short and would not affect practical applications. The model parameters are the same as the results on pooled raw data analyzed in SAS, demonstrating high model accuracy. Conclusion The proposed protocol and prototype system would allow the development of logistic regression models in a secure manner without requiring the sharing of personal health information. This can alleviate one of the key barriers to the establishment of large-scale post-marketing surveillance programs. We extended the secure protocol to account for

  14. Comparison of two isometric handgrip protocols on sympathetic arousal in women.

    PubMed

    Nielsen, Shawn E; Mather, Mara

    2015-04-01

    Isometric handgrip is commonly used in stress research because the task reliably increases sympathetic arousal. Various handgrip protocols have been used; they vary in handgrip strength, duration of grip, and the number of cycles of handgrip and rest. However, most protocols require the calibration of a maximum voluntary contraction (MVC) prior to the handgrip task, which is not always convenient (i.e., in a functional magnetic resonance imaging study). Here, we wanted to test whether two handgrip protocols with different strength, duration and cycle protocols would reliably elicit sympathetic arousal in the absence of calibrating an MVC. Sixty-two healthy naturally cycling women and women on hormonal contraception participated in one of the two isometric handgrip protocols using a hand therapy ball of medium resistance. Women completed one of the following handgrip protocols: 1) 30% of a perceived maximum voluntary contraction for 3 min or 2) 3 cycles of maximum voluntary contraction for 18s with a one minute rest in between. All handgrip blocks were counterbalanced with a control condition. Sympathetic arousal was measured throughout the session via pupil diameter changes and salivary alpha-amylase. Results indicate that in the absence of calibrating an MVC, the handgrip tasks elicited different changes in sympathetic arousal. Pupil dilation responses increased significantly in the handgrip versus control blocks only in participants in the 18-s protocol. Additionally, more participants exhibited a salivary alpha-amylase response to the handgrip block in the 18-s condition compared to the 3-min condition. Thus, these results suggest that neuroimaging and behavioral studies with isometric handgrip should be able to successfully induce sympathetic nervous activity with the 18-s paradigm, regardless of the handgrip device and the ability to calibrate an MVC.

  15. An efficient and reliable geographic routing protocol based on partial network coding for underwater sensor networks.

    PubMed

    Hao, Kun; Jin, Zhigang; Shen, Haifeng; Wang, Ying

    2015-01-01

    Efficient routing protocols for data packet delivery are crucial to underwater sensor networks (UWSNs). However, communication in UWSNs is a challenging task because of the characteristics of the acoustic channel. Network coding is a promising technique for efficient data packet delivery thanks to the broadcast nature of acoustic channels and the relatively high computation capabilities of the sensor nodes. In this work, we present GPNC, a novel geographic routing protocol for UWSNs that incorporates partial network coding to encode data packets and uses sensor nodes' location information to greedily forward data packets to sink nodes. GPNC can effectively reduce network delays and retransmissions of redundant packets causing additional network energy consumption. Simulation results show that GPNC can significantly improve network throughput and packet delivery ratio, while reducing energy consumption and network latency when compared with other routing protocols.

  16. An Efficient and Reliable Geographic Routing Protocol Based on Partial Network Coding for Underwater Sensor Networks

    PubMed Central

    Hao, Kun; Jin, Zhigang; Shen, Haifeng; Wang, Ying

    2015-01-01

    Efficient routing protocols for data packet delivery are crucial to underwater sensor networks (UWSNs). However, communication in UWSNs is a challenging task because of the characteristics of the acoustic channel. Network coding is a promising technique for efficient data packet delivery thanks to the broadcast nature of acoustic channels and the relatively high computation capabilities of the sensor nodes. In this work, we present GPNC, a novel geographic routing protocol for UWSNs that incorporates partial network coding to encode data packets and uses sensor nodes’ location information to greedily forward data packets to sink nodes. GPNC can effectively reduce network delays and retransmissions of redundant packets causing additional network energy consumption. Simulation results show that GPNC can significantly improve network throughput and packet delivery ratio, while reducing energy consumption and network latency when compared with other routing protocols. PMID:26029955

  17. W-MAC: a workload-aware MAC protocol for heterogeneous convergecast in wireless sensor networks.

    PubMed

    Xia, Ming; Dong, Yabo; Lu, Dongming

    2011-01-01

    The power consumption and latency of existing MAC protocols for wireless sensor networks (WSNs) are high in heterogeneous convergecast, where each sensor node generates different amounts of data in one convergecast operation. To solve this problem, we present W-MAC, a workload-aware MAC protocol for heterogeneous convergecast in WSNs. A subtree-based iterative cascading scheduling mechanism and a workload-aware time slice allocation mechanism are proposed to minimize the power consumption of nodes, while offering a low data latency. In addition, an efficient schedule adjustment mechanism is provided for adapting to data traffic variation and network topology change. Analytical and simulation results show that the proposed protocol provides a significant energy saving and latency reduction in heterogeneous convergecast, and can effectively support data aggregation to further improve the performance.

  18. Survey of Software Problems with Impacts to 'Campout' Protocol Extravehicular Activity (EVA) Prebreathe

    NASA Technical Reports Server (NTRS)

    Diderich, Greg; Matty, Christopher M.

    2009-01-01

    During International Space Station campout protocol ExtraVehicular Activity (EVA) preparations, the crew is isolated overnight in the small airlock volume in a reduced pressure, oxygen enriched atmosphere. As such, there are special considerations for the software in terms of air composition, pressure control and emergency responses. For one, the ISS software must monitor and manage two distinct atmospheres. Also, the small airlock volume is especially sensitive to small changes in the environment, and what would be a minor emergency in the larger vehicle volume can have catastrophic results in the isolated airlock. Finally, in cases of emergency, the crew needs to rapidly egress the airlock, which requires an aggressive automatic repressurization to equalize pressure on the hatch. This paper will describe the software which is modified for the airlock campout protocol. In addition, the paper will describe the software problems and hardware problems with software workarounds which have affected campout protocol.

  19. The Impact of the Unified Protocol for Emotional Disorders on Quality of Life

    PubMed Central

    Gallagher, Matthew W.; Sauer-Zavala, Shannon E.; Boswell, James F.; Carl, Jenna R.; Bullis, Jackie; Farchione, Todd J.; Barlow, David H.

    2013-01-01

    It has become increasingly clear that mental health is more than just the absence of psychopathology and that there is clinical utility in examining positive aspects of mental health. The present study examined the effects of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders on quality of life in a randomized controlled trial that included individuals with a diverse range of emotional disorders. Results indicated that the Unified Protocol produced significant increases in quality of life when examining both within-individual effect sizes and between-conditions effect sizes compared to a waitlist condition. Furthermore, results indicated that post-treatment levels of quality of life predicted levels of functional impairment independently of diagnostic severity. These results provide further evidence of the importance of examining indicators of mental health in conjunction with markers of psychopathology and provide promising evidence that the Unified Protocol may promote improved mental health in addition to treating psychopathology. PMID:24358405

  20. Enantioselective Michael Addition of Water

    PubMed Central

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-01-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry. PMID:25529526

  1. Enantioselective Michael addition of water.

    PubMed

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-02-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry.

  2. 48 CFR 3439.701 - Internet Protocol version 6.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Internet Protocol version... Requirements for Acquisition of Information Technology 3439.701 Internet Protocol version 6. The contracting officer must insert the clause at 3452.239-70 (Internet protocol version 6 (IPv6)) in all...

  3. 48 CFR 3439.701 - Internet Protocol version 6.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Internet Protocol version 6... for Acquisition of Information Technology 3439.701 Internet Protocol version 6. The contracting officer must insert the clause at 3452.239-70 (Internet protocol version 6 (IPv6)) in all...

  4. 48 CFR 3439.701 - Internet Protocol version 6.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Internet Protocol version... Requirements for Acquisition of Information Technology 3439.701 Internet Protocol version 6. The contracting officer must insert the clause at 3452.239-70 (Internet protocol version 6 (IPv6)) in all...

  5. 48 CFR 3439.701 - Internet Protocol version 6.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Internet Protocol version... Requirements for Acquisition of Information Technology 3439.701 Internet Protocol version 6. The contracting officer must insert the clause at 3452.239-70 (Internet protocol version 6 (IPv6)) in all...

  6. 21 CFR 814.19 - Product development protocol (PDP).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Product development protocol (PDP). 814.19 Section...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.19 Product development protocol (PDP). A class III device for which a product development protocol has been declared completed by FDA...

  7. Tendencies in the development of utilization protocols, seminar report

    NASA Astrophysics Data System (ADS)

    Roveri, A.

    1983-07-01

    The open system interconnections model (OSI) structured approach to specify protocols is discussed. A stratification in seven levels characterizes the architecture of the system. Transfer level protocol characterization of utilization protocols in the OSI model, data flow control, and presentation and application levels are described.

  8. The Interlibrary Loan Protocol: An OSI Solution to ILL Messaging.

    ERIC Educational Resources Information Center

    Turner, Fay

    1990-01-01

    Discusses the interlibrary loan (ILL) protocol, a standard based on the principles of the Open Systems Interconnection (OSI) Reference Model. Benefits derived from protocol use are described, the status of the protocol as an international standard is reviewed, and steps taken by the National Library of Canada to facilitate migration to an ILL…

  9. A Biometric Authenticated Key Agreement Protocol for Secure Token

    NASA Astrophysics Data System (ADS)

    Yoon, Eun-Jun; Yoo, Kee-Young

    This letter proposes a robust biometric authenticated key agreement (BAKA) protocol for a secure token to provide strong security and minimize the computation cost of each participant. Compared with other related protocols, the proposed BAKA protocol not only is secure against well-known cryptographical attacks but also provides various functionality and performance requirements.

  10. DEVELOPMENT OF MODELING PROTOCOLS FOR USE IN DETERMINING SEDIMENT TMDLS

    EPA Science Inventory

    Modeling protocols for use in determining sediment TMDLs are being developed to provide the Office of Water, Regions and the States with assistance in determining TMDLs for sediment impaired water bodies. These protocols will supplement the protocols developed by the Office of W...

  11. Gasoline additives, emissions, and performance

    SciTech Connect

    1995-12-31

    The papers included in this publication deal with the influence of fuel, additive, and hardware changes on a variety of vehicle performance characteristics. Advanced techniques for measuring these performance parameters are also described. Contents include: Fleet test evaluation of gasoline additives for intake valve and combustion chamber deposit clean up; A technique for evaluating octane requirement additives in modern engines on dynamometer test stands; A fleet test of two additive technologies comparing their effects on tailpipe emissions; Investigation into the vehicle exhaust emissions of high percentage ethanol blends; Variability in hydrocarbon speciation measurements at low emission (ULEV) levels; and more.

  12. Spacelab system analysis: The modified free access protocol: An access protocol for communication systems with periodic and Poisson traffic

    NASA Technical Reports Server (NTRS)

    Ingels, Frank; Owens, John; Daniel, Steven

    1989-01-01

    The protocol definition and terminal hardware for the modified free access protocol, a communications protocol similar to Ethernet, are developed. A MFA protocol simulator and a CSMA/CD math model are also developed. The protocol is tailored to communication systems where the total traffic may be divided into scheduled traffic and Poisson traffic. The scheduled traffic should occur on a periodic basis but may occur after a given event such as a request for data from a large number of stations. The Poisson traffic will include alarms and other random traffic. The purpose of the protocol is to guarantee that scheduled packets will be delivered without collision. This is required in many control and data collection systems. The protocol uses standard Ethernet hardware and software requiring minimum modifications to an existing system. The modification to the protocol only affects the Ethernet transmission privileges and does not effect the Ethernet receiver.

  13. A universal data access and protocol integration mechanism for smart home

    NASA Astrophysics Data System (ADS)

    Shao, Pengfei; Yang, Qi; Zhang, Xuan

    2013-03-01

    With the lack of standardized or completely missing communication interfaces in home electronics, there is no perfect solution to address every aspect in smart homes based on existing protocols and technologies. In addition, the central control unit (CCU) of smart home system working point-to-point between the multiple application interfaces and the underlying hardware interfaces leads to its complicated architecture and unpleasant performance. A flexible data access and protocol integration mechanism is required. The current paper offers a universal, comprehensive data access and protocol integration mechanism for a smart home. The universal mechanism works as a middleware adapter with unified agreements of the communication interfaces and protocols, offers an abstraction of the application level from the hardware specific and decoupling the hardware interface modules from the application level. Further abstraction for the application interfaces and the underlying hardware interfaces are executed based on adaption layer to provide unified interfaces for more flexible user applications and hardware protocol integration. This new universal mechanism fundamentally changes the architecture of the smart home and in some way meets the practical requirement of smart homes more flexible and desirable.

  14. Landbird Monitoring Protocol for National Parks in the North Coast and Cascades Network

    USGS Publications Warehouse

    Siegel, Rodney B.; Wilkerson, Robert L.; Jenkins, Kurt J.; Kuntz, Robert C.; Boetsch, John R.; Schaberl, James P.; Happe, Patricia J.

    2007-01-01

    This protocol narrative outlines the rationale, sampling design and methods for monitoring landbirds in the North Coast and Cascades Network (NCCN) during the breeding season. The NCCN, one of 32 networks of parks in the National Park System, comprises seven national park units in the Pacific Northwest, including three large, mountainous, natural area parks (Mount Rainier [MORA] and Olympic [OLYM] National Parks, North Cascades National Park Service Complex [NOCA]), and four small historic cultural parks (Ebey's Landing National Historical Reserve [EBLA], Lewis and Clark National Historical Park [LEWI], Fort Vancouver National Historical Park [FOVA], and San Juan Island National Historical Park [SAJH]). The protocol reflects decisions made by the NCCN avian monitoring group, which includes NPS representatives from each of the large parks in the Network as well as personnel from the U.S. Geological Survey Forest and Rangeland Ecosystem Science Center (USGS-FRESC) Olympic Field Station, and The Institute for Bird Populations, at meetings held between 2000 (Siegel and Kuntz, 2000) and 2005. The protocol narrative describes the monitoring program in relatively broad terms, and its structure and content adhere to the outline and recommendations developed by Oakley and others (2003) and adopted by NPS. Finer details of the methodology are addressed in a set of standard operating procedures (SOPs) that accompany the protocol narrative. We also provide appendixes containing additional supporting materials that do not clearly belong in either the protocol narrative or the standard operating procedures.

  15. A standard protocol for describing individual-based and agent-based models

    USGS Publications Warehouse

    Grimm, Volker; Berger, Uta; Bastiansen, Finn; Eliassen, Sigrunn; Ginot, Vincent; Giske, Jarl; Goss-Custard, John; Grand, Tamara; Heinz, Simone K.; Huse, Geir; Huth, Andreas; Jepsen, Jane U.; Jorgensen, Christian; Mooij, Wolf M.; Muller, Birgit; Pe'er, Guy; Piou, Cyril; Railsback, Steven F.; Robbins, Andrew M.; Robbins, Martha M.; Rossmanith, Eva; Ruger, Nadja; Strand, Espen; Souissi, Sami; Stillman, Richard A.; Vabo, Rune; Visser, Ute; DeAngelis, Donald L.

    2006-01-01

    Simulation models that describe autonomous individual organisms (individual based models, IBM) or agents (agent-based models, ABM) have become a widely used tool, not only in ecology, but also in many other disciplines dealing with complex systems made up of autonomous entities. However, there is no standard protocol for describing such simulation models, which can make them difficult to understand and to duplicate. This paper presents a proposed standard protocol, ODD, for describing IBMs and ABMs, developed and tested by 28 modellers who cover a wide range of fields within ecology. This protocol consists of three blocks (Overview, Design concepts, and Details), which are subdivided into seven elements: Purpose, State variables and scales, Process overview and scheduling, Design concepts, Initialization, Input, and Submodels. We explain which aspects of a model should be described in each element, and we present an example to illustrate the protocol in use. In addition, 19 examples are available in an Online Appendix. We consider ODD as a first step for establishing a more detailed common format of the description of IBMs and ABMs. Once initiated, the protocol will hopefully evolve as it becomes used by a sufficiently large proportion of modellers.

  16. Direct preparation protocol to obtain mitotic chromosomes from canine mammary tumors.

    PubMed

    Morais, C S D; Affonso, P R A M; Bitencourt, J A; Wenceslau, A A

    2015-12-29

    Currently, mammary neoplasms in female canines are a serious problem in veterinary clinics. In addition, the canine species is an excellent disease model for human oncology because of the biological and genetic similarities between the species. Cytogenetics has allowed further study of the characterization of neoplasms in canines. We hypothesized that the use of a direct preparation protocol for mitotic chromosome analysis would provide a simple and low cost protocol for use in all laboratories. The objective of this method is to display in a few hours of dividing cells just like the time of collection since cell division in tissue can be obtained. Ten female canines with the spontaneous occurrence of mammary neoplasia were used to test a pioneering direct preparation protocol to obtain mitotic chromosomes. The excised breast tumor tissue fragments were subjected to the protocol consisting of treatment with colchicine, treatment with hypotonic solution, and fixation. Mitotic chromosomes were absent in cell suspensions of only two samples among the 10 materials analyzed, based on the analysis of five blades for each preparation obtained. So, the cell suspension obtained allowed for the observation of eight tissue samples viable for cytogenetic analysis, five of which had excellent numbers of mitotic chromosomes. However, the technique was unsuccessful in producing high-quality cell suspensions because of inadequate condensation and scattering of chromosomes. While adjustments to methodological procedures are needed, this protocol represents a low cost and simplified method to study the cytogenetics of canine tumors.

  17. A monitoring protocol to assess tidal restoration of salt marshes on local and regional scales

    USGS Publications Warehouse

    Neckles, H.A.; Dionne, M.D.; Burdick, D.M.; Roman, C.T.; Buchsbaum, R.; Hutchins, E.

    2002-01-01

    Assessing the response of salt marshes to tidal restoration relies on comparisons of ecosystem attributes between restored and reference marshes. Although this approach provides an objective basis for judging project success, inferences can be constrained if the high variability of natural marshes masks differences in sampled attributes between restored and reference sites. Furthermore, such assessments are usually focused on a small number of restoration projects in a local area, limiting the ability to address questions regarding the effectiveness of restoration within a broad region. We developed a hierarchical approach to evaluate the performance of tidal restorations at local and regional scales throughout the Gulf of Maine. The cornerstone of the approach is a standard protocol for monitoring restored and reference salt marshes throughout the region. The monitoring protocol was developed by consensus among nearly 50 restoration scientists and practitioners. The protocol is based on a suite of core structural measures that can be applied to any tidal restoration project. The protocol also includes additional functional measures for application to specific projects. Consistent use of the standard protocol to monitor local projects will enable pooling information for regional assessments. Ultimately, it will be possible to establish a range of reference conditions characterizing natural tidal wetlands in the region and to compare performance curves between populations of restored and reference marshes for assessing regional restoration effectiveness.

  18. Rehabilitation protocol for patellar tendinopathy applied among 16- to 19-year old volleyball players.

    PubMed

    Biernat, Ryszard; Trzaskoma, Zbigniew; Trzaskoma, Lukasz; Czaprowski, Dariusz

    2014-01-01

    The aim of the study was to investigate the efficacy of rehabilitation protocol applied during competitive period for the treatment of patellar tendinopathy. A total of 28 male volleyball players were divided into two groups. Fifteen from experimental group (E) and 13 from control group (C) fulfilled the same tests 3 times: before the training program started (first measurement), after 12 weeks (second measurement) and after 24 weeks (third measurement). The above-mentioned protocol included the following: USG imagining with color Doppler function, clinical testing, pain intensity evaluation with VISA-P questionnaire, leg muscle strength and power and jumping ability measurements. The key element of the rehabilitation program was eccentric squat on decline board with additional unstable surface. The essential factor of the protocol was a set of preventive functional exercises, with focus on eccentric exercises of hamstrings. Patellar tendinopathy was observed in 18% of the tested young volleyball players. Implementation of the presented rehabilitation protocol with eccentric squat on decline board applied during sports season lowered the pain level of the young volleyball players. Presented rehabilitation protocol applied without interrupting the competitive period among young volleyball players together with functional exercises could be an effective method for the treatment of patellar tendinopathy. PMID:23669814

  19. Single pulse frequency compounding protocol for superharmonic imaging

    NASA Astrophysics Data System (ADS)

    Danilouchkine, M. G.; van Neer, P. L. M. J.; Verweij, M. D.; Matte, G. M.; Vletter, W. B.; van der Steen, A. F. W.; de Jong, N.

    2013-07-01

    Second harmonic imaging is currently accepted as the standard in commercial echographic systems. A new imaging technique, coined as superharmonic imaging (SHI), combines the third till the fifth harmonics, arising during nonlinear sound propagation. It could further enhance the resolution and quality of echographic images. To meet the bandwidth requirement for SHI a dedicated phased array has been developed: a low frequency subarray, intended for transmission, interleaved with a high frequency subarray, used in reception. As the bandwidth of the elements is limited, the spectral gaps in between the harmonics cause multiple (ghost) reflection artifacts. A dual-pulse frequency compounding method aims at suppressing those artifacts at a price of a reduced frame rate. In this study we explore a possibility of performing frequency compounding within a single transmission. The traditional frequency compounding method suppresses the ripples by consecutively emitting two short Gaussian bursts with a slightly different center frequency. In the newly proposed method, the transmit aperture is divided into two parts: the first half is used to send a pulse at the lower center frequency, while the other half simultaneously transmits at a slightly higher center frequency. The suitability of the protocol for medical imaging applications in terms of the steering capabilities was performed in a simulation study with INCS and the hydrophone measurements. Moreover, an experimental study was carried out to find the optimal parameters for the clinical imaging protocol. The latter was subsequently used to obtain the images of a tissue mimicking phantom containing strongly reflecting wires. Additionally, the images of a human heart in the parasternal projection were acquired. The scanning aperture with the developed protocol amounts to approximately 90°, which is sufficient to capture the cardiac structures in the standard anatomical projections. The theoretically estimated and

  20. Color Addition and Subtraction Apps

    ERIC Educational Resources Information Center

    Ruiz, Frances; Ruiz, Michael J.

    2015-01-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…