76 FR 73494 - Airworthiness Directives; Turbomeca S.A. Arriel 2B Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... identified in the MCAI. The one-time functional test required by the service bulletin is not a normal engine run-up test: the one-time functional test involves additional requirements including mode switching, that are not part of a normal engine run-up after start. FAA's Determination and Requirements of This...

20 CFR 404.1283 - Exceptions to the time limitations on credits or refunds-for wages paid prior to 1987.

Code of Federal Regulations, 2010 CFR

2010-04-01

... or refunds-for wages paid prior to 1987. 404.1283 Section 404.1283 Employees' Benefits SOCIAL... known error which require additional time to complete; or (iii) The Social Security Administration is... additional time is needed to make a determination; or (iv) The Social Security Administration has not issued...

20 CFR 404.1283 - Exceptions to the time limitations on credits or refunds-for wages paid prior to 1987.

Code of Federal Regulations, 2011 CFR

2011-04-01

... or refunds-for wages paid prior to 1987. 404.1283 Section 404.1283 Employees' Benefits SOCIAL... known error which require additional time to complete; or (iii) The Social Security Administration is... additional time is needed to make a determination; or (iv) The Social Security Administration has not issued...

26 CFR 301.6110-5 - Notice and time requirements; actions to restrain disclosure; actions to obtain additional...

Code of Federal Regulations, 2010 CFR

2010-04-01

...) any third-party communication notations required to be placed pursuant to § 301.6110-4(a) on the face... a written determination on which a third-party communication notation has been placed pursuant to... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Notice and time requirements; actions to...

7 CFR 3430.42 - Special award conditions.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) General. CSREES may, with respect to any award, impose additional conditions prior to or at the time of... needed; the time allowed for completing the corrective actions; and the method for requesting reconsideration of the additional requirements imposed. (c) Form CSREES-2009, Award Face Sheet. These special...

47 CFR 25.111 - Additional information.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or any...

47 CFR 25.111 - Additional information.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 2 2012-10-01 2012-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or any...

47 CFR 25.111 - Additional information.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or any...

78 FR 42323 - Pilot Certification and Qualification Requirements for Air Carrier Operations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-15

... sufficient. \\4\\ In addition, military PIC time (up to 500 hours) in a multiengine turbine-powered, fixed-wing... aerodynamic stall (insufficient airflow over the wings). The flightcrew's response to the stall warning system.... Military PIC time in a multiengine turbine-powered, fixed-wing airplane in an operation requiring more than...

Can We Apply TAM in Computer-Based Classes?

ERIC Educational Resources Information Center

Williams, David; Williams, Denise

2013-01-01

While students may struggle in any classroom and consequently require help beyond the schedule meeting time and place of the class, computer-based courses pose the additional hurdle of requiring ready access to hardware and software that may be unavailable or inconvenient for students outside of the classroom and its scheduled meeting time. This…

75 FR 41438 - Stainless Steel Bar from India: Extension of Time Limit for the Final Results of the 2008-2009...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

..., following the preliminary results, the Department received additional cost information from Venus, as... a comprehensive cost analysis, significantly delaying the briefing schedule. See Memorandum from..., the Department requires additional time to review and address the detail and complexity of the cost...

The Cassini project: Lessons learned through operations

NASA Astrophysics Data System (ADS)

McCormick, Egan D.

1998-01-01

The Cassini space probe requires 180 238Pu Light-weight Radioisotopic Heater Units (LWRHU) and 216 238Pu General Purpose Heat Source (GPHS) pellets. Additional LWRHU and GPHS pellets required for non-destructive (NDA) and destructive assay purposes were fabricated bringing the original pellet requirement to 224 LWRHU and 252 GPHS. Due to rejection of pellets resulting from chemical impurities in the fuel and/or failure to meet dimensional specifications a total of 320 GPHS pellets were fabricated for the mission. Initial plans called for LANL to process a total of 30 kg of oxide powder for pressing into monolithic ceramic pellets. The original 30 kg commitment was processed within the time frame allotted; an additional 8 kg were required to replace fuel lost due to failure to meet Quality Assurance specifications for impurities and dimensions. During the time frame allotted for pellet production, operations were impacted by equipment failure, unacceptable fuel impurities levels, and periods of extended down time, >30 working days during which little or no processing occurred. Throughout the production process, the reality of operations requirements varied from the theory upon which production schedules were based.

Running DNA Mini-Gels in 20 Minutes or Less Using Sodium Boric Acid Buffer

ERIC Educational Resources Information Center

Jenkins, Kristin P.; Bielec, Barbara

2006-01-01

Providing a biotechnology experience for students can be challenging on several levels, and time is a real constraint for many experiments. Many DNA based methods require a gel electrophoresis step, and although some biotechnology procedures have convenient break points, gel electrophoresis does not. In addition to the time required for loading…

An analysis of thermal response factors and how to reduce their computational time requirement

NASA Technical Reports Server (NTRS)

Wiese, M. R.

1982-01-01

Te RESFAC2 version of the Thermal Response Factor Program (RESFAC) is the result of numerous modifications and additions to the original RESFAC. These modifications and additions have significantly reduced the program's computational time requirement. As a result of this work, the program is more efficient and its code is both readable and understandable. This report describes what a thermal response factor is; analyzes the original matrix algebra calculations and root finding techniques; presents a new root finding technique and streamlined matrix algebra; supplies ten validation cases and their results.

A Geometric Analysis to Protect Manned Assets from Newly Launched Objects - Cola Gap Analysis

NASA Technical Reports Server (NTRS)

Hametz, Mark E.; Beaver, Brian A.

2013-01-01

A safety risk was identified for the International Space Station (ISS) by The Aerospace Corporation, where the ISS would be unable to react to a conjunction with a newly launched object following the end of the launch Collision Avoidance (COLA) process. Once an object is launched, there is a finite period of time required to track, catalog, and evaluate that new object as part of standard onorbit COLA screening processes. Additionally, should a conjunction be identified, there is an additional period of time required to plan and execute a collision avoidance maneuver. While the computed prelaunch probability of collision with any object is extremely low, NASA/JSC has requested that all US launches take additional steps to protect the ISS during this "COLA gap" period. This paper details a geometric-based COLA gap analysis method developed by the NASA Launch Services Program to determine if launch window cutouts are required to mitigate this risk. Additionally, this paper presents the results of several missions where this process has been used operationally.

The Requirements Generation System: A tool for managing mission requirements

NASA Technical Reports Server (NTRS)

Sheppard, Sylvia B.

1994-01-01

Historically, NASA's cost for developing mission requirements has been a significant part of a mission's budget. Large amounts of time have been allocated in mission schedules for the development and review of requirements by the many groups who are associated with a mission. Additionally, tracing requirements from a current document to a parent document has been time-consuming and costly. The Requirements Generation System (RGS) is a computer-supported cooperative-work tool that assists mission developers in the online creation, review, editing, tracing, and approval of mission requirements as well as in the production of requirements documents. This paper describes the RGS and discusses some lessons learned during its development.

Dredging Research Program. Dredge Mooring Study, Recommended Design, Phase 2 Report

DTIC Science & Technology

1992-05-01

describes the amount of dock space and staging area required (250 ft by 300 ft of dock space), crane requirements (a 50- to 60-ton crane ), and time and...including a diver) in 1 week or less (5 days minimum). With the addition of a second crane and second anchor handling vessel, the assembly and installation...describes the amount of dock space and staging area required (250 ft by 300 ft of dock space), crane requirements (a 50- to 60-ton crane ), and time and

30 CFR 71.701 - Sampling; general requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Sampling; general requirements. 71.701 Section... MINES Airborne Contaminants § 71.701 Sampling; general requirements. (a) Air samples will be taken by... operator shall conduct any additional air sampling tests and analyses as the Secretary may from time to...

30 CFR 71.701 - Sampling; general requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Sampling; general requirements. 71.701 Section... MINES Airborne Contaminants § 71.701 Sampling; general requirements. (a) Air samples will be taken by... operator shall conduct any additional air sampling tests and analyses as the Secretary may from time to...

40 CFR 79.5 - Periodic reporting requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 17 2014-07-01 2014-07-01 false Periodic reporting requirements. 79.5...) REGISTRATION OF FUELS AND FUEL ADDITIVES General Provisions § 79.5 Periodic reporting requirements. (a) Fuel... table: Table 1 to § 79.5—Quarterly Reporting Deadlines Calendar quarter Time period covered Quartely...

33 CFR 148.107 - What additional information may be required?

Code of Federal Regulations, 2010 CFR

2010-07-01

... HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Application for a License § 148.107...), in coordination with MARAD, may determine whether compliance with the requirement is important to processing the application within the time prescribed by the Act. (3) If the requirement is important to...

10 CFR 810.14 - Additional information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The Department of Energy may at any time require a person engaging in any generally or specifically authorized...

10 CFR 810.14 - Additional information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The Department of Energy may at any time require a person engaging in any generally or specifically authorized...

10 CFR 810.14 - Additional information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The Department of Energy may at any time require a person engaging in any generally or specifically authorized...

10 CFR 810.14 - Additional information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The Department of Energy may at any time require a person engaging in any generally or specifically authorized...

75 FR 17378 - Stainless Steel Sheet and Strip in Coils from Taiwan: Notice of Extension of Time Limits for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

...). On July 28, 2009, Chia Far Industrial Factory Co., Ltd. (Chia Far) requested an administrative review..., 2009, the petitioners\\1\\ requested a review with respect to Chia Far and 22 additional companies. \\1... Act because we require additional time to analyze and verify the data submitted by Chia Far, the sole...

A study of the additional costs of dispensing workers' compensation prescriptions.

PubMed

Schafermeyer, Kenneth W

2007-03-01

Although there is a significant amount of additional work involved in dispensing workers' compensation prescriptions, these costs have not been quantified. A study of the additional costs to dispense a workers' compensation prescription is needed to measure actual costs and to help determine the reasonableness of reimbursement for prescriptions dispensed under workers' compensation programs. The purpose of this study was to determine the minimum additional time and costs required to dispense workers' compensation prescriptions in Texas. A convenience sample of 30 store-level pharmacy staff members involved in submitting and processing prescription claims for the Texas Mutual workers' compensation program were interviewed by telephone. Data collected to determine the additional costs of dispensing a workers' compensation prescription included (1) the amount of additional time and personnel costs required to dispense and process an average workers' compensation prescription claim, (2) the difference in time required for a new versus a refilled prescription, (3) overhead costs for processing workers' compensation prescription claims by experienced experts at a central processing facility, (4) carrying costs for workers' compensation accounts receivable, and (5) bad debts due to uncollectible workers' compensation claims. The median of the sample pharmacies' additional costs for dispensing a workers' compensation prescription was estimated to be at least $9.86 greater than for a cash prescription. This study shows that the estimated costs for workers' compensation prescriptions were significantly higher than for cash prescriptions. These costs are probably much more than most employers, workers' compensation payers, and pharmacy managers would expect. It is recommended that pharmacy managers should estimate their own costs and compare these costs to actual reimbursement when considering the reasonableness of workers' compensation prescriptions and whether to accept these prescriptions.

76 FR 44305 - Honey From Argentina: Extension of Time Limit for Preliminary Results of Antidumping Duty New...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

...: Extension of Time Limit for Preliminary Results of Antidumping Duty New Shipper Review AGENCY: Import... results of this review is July 24, 2011. Extension of Time Limits for Preliminary Results of Review... time to complete the preliminary results. Specifically, the Department requires additional time to...

43 CFR 3430.4-2 - Additional information.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Additional information. 3430.4-2 Section... Leases § 3430.4-2 Additional information. (a) If the applicant for a preference right lease has submitted timely, some, but not all of the information required in § 3430.4-1 of this title, the authorized officer...

Reentry Vehicle On-Site Inspection Technology Study

DTIC Science & Technology

1994-11-01

masking Image Additional required* generated information required/wquied Pasive radiation Neutron scanning Neutron dose rate PNS Yes No SRS/BMO Yes...considerations for RVOSI techbologles. Inspection methods Instrument Setup Data Host support proximity time collection (m) (hr) time (hir) Pasive radiation...The unwillingness of our own services to allow equipment in close proximity to missile front ends is a matter which will have to be considered if a

Engineering and fabrication cost considerations for cryogenic wind tunnel models

NASA Technical Reports Server (NTRS)

Boykin, R. M., Jr.; Davenport, J. B., Jr.

1983-01-01

Design and fabrication cost drivers for cryogenic transonic wind tunnel models are defined. The major cost factors for wind tunnel models are model complexity, tolerances, surface finishes, materials, material validation, and model inspection. The cryogenic temperatures require the use of materials with relatively high fracture toughness but at the same time high strength. Some of these materials are very difficult to machine, requiring extensive machine hours which can add significantly to the manufacturing costs. Some additional engineering costs are incurred to certify the materials through mechanical tests and nondestructive evaluation techniques, which are not normally required with conventional models. When instrumentation such as accelerometers and electronically scanned pressure modules is required, temperature control of these devices needs to be incorporated into the design, which requires added effort. Additional thermal analyses and subsystem tests may be necessary, which also adds to the design costs. The largest driver to the design costs is potentially the additional static and dynamic analyses required to insure structural integrity of the model and support system.

Virtual Surgical Planning for Inferior Alveolar Nerve Reconstruction.

PubMed

Miloro, Michael; Markiewicz, Michael R

2017-11-01

The purpose of this study was to assess the outcomes after preoperative virtual surgical planning (VSP) for inferior alveolar nerve (IAN) reconstruction in ablative mandibular surgery. We performed a retrospective evaluation of consecutive surgical cases using standard VSP for hard tissue resection and reconstructive surgery in addition to IAN VSP performed simultaneously during surgery. Cases were assessed regarding the planning time, additional costs involved, surgeon's subjective impression of the process, accuracy of the prediction during surgery, and operative time during surgery compared with cases performed without VSP. The study sample was composed of 5 cases of mandibular resection for benign disease, with bony, soft tissue, and neural reconstruction with the use of VSP. The addition of IAN reconstruction to the VSP session added no additional expense to the planning session but resulted in an additional 22.5 minutes (±7.5 minutes) for the webinar session. From a subjective standpoint, IAN VSP provided the surgeon with a discreet plan for surgery. From an objective standpoint, IAN VSP provided the exact length and diameter of nerve graft required for surgery, facilitated the surgeon's ability to visualize the actual nerve graft procedure, and limited the additional time required for simultaneous nerve reconstruction. Despite perceived prejudice against simultaneous IAN reconstruction with complex mandibular resection and reconstruction, the use of IAN VSP may facilitate the actual surgical procedure and result in considerably improved patient outcomes without considerable additional time or cost associated with this protocol. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Teaching Online: Where Do Faculty Spend Their Time?

ERIC Educational Resources Information Center

Mandernach, B. Jean; Holbeck, Rick

2016-01-01

An understanding of online teaching time requirements provides essential information to inform scheduling, course size and instructor workload; in addition, awareness of the distribution of time across online teaching tasks provides insight to focus faculty efforts and tailor professional development to target instructional needs. The purpose of…

Additional requirements for charitable hospitals; community health needs assessments for charitable hospitals; requirement of a section 4959 excise tax return and time for filing the return. Final regulations and removal of temporary regulations.

PubMed

2014-12-31

This document contains final regulations that provide guidance regarding the requirements for charitable hospital organizations added by the Patient Protection and Affordable Care Act of 2010. The regulations will affect charitable hospital organizations

76 FR 36610 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

... rather than by series; (b) adopt a $5 quotation spread parameter; and (c) amend the quoting requirement... additional time to adapt to the enhancements. \\4\\ The Exchange has also filed other proposed rule changes in... additional time to adapt to the enhancements. \\8\\ 15 U.S.C. 78f(b). \\9\\ 15 U.S.C. 78f(b)(5). B. Self...

Time Manager Software for a Flight Processor

NASA Technical Reports Server (NTRS)

Zoerne, Roger

2012-01-01

Data analysis is a process of inspecting, cleaning, transforming, and modeling data to highlight useful information and suggest conclusions. Accurate timestamps and a timeline of vehicle events are needed to analyze flight data. By moving the timekeeping to the flight processor, there is no longer a need for a redundant time source. If each flight processor is initially synchronized to GPS, they can freewheel and maintain a fairly accurate time throughout the flight with no additional GPS time messages received. How ever, additional GPS time messages will ensure an even greater accuracy. When a timestamp is required, a gettime function is called that immediately reads the time-base register.

Removal torque of nail interlocking screws is related to screw proximity to the fracture and screw breakage.

PubMed

White, Alexander A; Kubacki, Meghan R; Samona, Jason; Telehowski, Paul; Atkinson, Patrick J

2016-06-01

Studies have shown that titanium implants can be challenging to explant due to the material's excellent biocompatibility and resulting osseointegration. Clinically, titanium alloy nail interlocking screws may require removal to dynamize a construct or revise the nail due to nonunion, infection, pain, or periprosthetic fracture. This study was designed to determine what variables influence the removal torque for titanium alloy interlocking screws. An intramedullary nail with four interlocking screws was used to stabilize a 1-cm segmental femoral defect in a canine model for 16 weeks. The animals were observed to be active following a several-day recovery after surgery. In six animals, the femora and implanted nail/screws were first tested to failure in torsion to simulate periprosthetic fracture of an implant after which the screws were then removed. In four additional animals, the screws were removed without mechanical testing. Both intraoperative insertional and extraction torques were recorded for all screws. Mechanical testing to failure broke 10/24 screws. On average, the intact screws required 70% of the insertional torque during removal while broken screws only required 16% of the insertional torque (p < 0.001). In addition, intact screws closer to the fracture required 2.8 times more removal torque than the outboard distal screw (p < 0.005). On average, the angle of rotation to peak torque was ∼80°. The peak axial load did not significantly correlate with the torque required to remove the screws. On average, the removal torque was lower than at the time of insertion, and less torque was required to remove broken screws and screws remote to the fracture. However, broken screws will require additional time to retrieve the remaining screw fragment. This study suggests that broken screws and screws in prematurely active patients will require less torque to remove. © IMechE 2016.

29 CFR 515.5 - Additional requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS UTILIZATION... such supplements to or provisions thereof as may be issued from time to time by the Division or the... of the Division and the Secretary of Labor may at any time, upon notifying the State agency, make...

29 CFR 515.5 - Additional requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS UTILIZATION... such supplements to or provisions thereof as may be issued from time to time by the Division or the... of the Division and the Secretary of Labor may at any time, upon notifying the State agency, make...

75 FR 44763 - Certain Circular Welded Non-Alloy Steel Pipe From Mexico; Extension of Time Limit for Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-29

...-Alloy Steel Pipe From Mexico; Extension of Time Limit for Preliminary Results of Antidumping Duty... review of the antidumping duty order on certain circular welded non- alloy steel pipe from Mexico. We... preliminary results of this review within the original time frame because we require additional time with...

30 CFR 250.803 - Additional production system requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... pressure vessels at any time when there is a change in operating pressures that requires new settings for... significant change in operating pressures. The most recent pressure-recorder charts used to determine... subfreezing climates, the lessee shall furnish evidence to the District Manager that the firefighting system...

30 CFR 250.803 - Additional production system requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... pressure vessels at any time when there is a change in operating pressures that requires new settings for... significant change in operating pressures. The most recent pressure-recorder charts used to determine... subfreezing climates, the lessee shall furnish evidence to the District Manager that the firefighting system...

30 CFR 250.803 - Additional production system requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pressure vessels at any time when there is a change in operating pressures that requires new settings for... significant change in operating pressures. The most recent pressure-recorder charts used to determine... subfreezing climates, the lessee shall furnish evidence to the District Manager that the firefighting system...

40 CFR 80.75 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... reformulated gasoline or RBOB produced or imported during the following time periods: (i) The first quarterly... to gasoline produced or imported during 1994 shall be included in the first quarterly report in 1995...) REGULATION OF FUELS AND FUEL ADDITIVES Reformulated Gasoline § 80.75 Reporting requirements. Any refiner or...

48 CFR 811.602 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... requirement as stated in the solicitation or offer. (6) The additional time the contractor claims is necessary... materials. (8) If applicable, a statement that the item required is for use in a construction contract that was authorized by the Director, Office of Construction and Facilities Management, to be awarded and...

48 CFR 811.602 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirement as stated in the solicitation or offer. (6) The additional time the contractor claims is necessary... materials. (8) If applicable, a statement that the item required is for use in a construction contract that was authorized by the Director, Office of Construction and Facilities Management, to be awarded and...

Ahead of the Times in Murfreesboro.

ERIC Educational Resources Information Center

Jones, John Hodge

1994-01-01

Murfreesboro (Tennessee) City Schools extended the school day and year with no additional cost to taxpayers. Implementation was arduous and faced great resistance. Eventual solution made better use of the school system's capital assets and human resources, rearranged Chapter 1 money, required additional business support and parents' willingness to…

75 FR 68702 - Regulation SHO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-09

... extended compliance period will give industry participants additional time for programming and testing for... time for programming and testing for compliance with the Rule's requirements. We have been informed that there have been some delays in the programming process, due in part to certain information, which...

40 CFR 63.1255 - Standards: Equipment leaks.

Code of Federal Regulations, 2014 CFR

2014-07-01

... considered part of this 3 month period. The monitoring required by this paragraph is in addition to the... needed, within 90 calendar days or by the next Periodic Report following the end of the monitoring period... a period of time for completion of required tasks (e.g., weekly, monthly, quarterly, annual) refer...

24 CFR 3286.307 - Process for obtaining trainer's qualification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... verification of the experience required in § 3286.305. This verification may be in the form of statements by past or present employers or a self-certification that the applicant meets those experience requirements, but HUD may contact the applicant for additional verification at any time. The applicant must...

76 FR 41056 - Amendment to Rule Filing Requirements for Dually-Registered Clearing Agencies

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-13

... we receive and intend to respond as necessary or appropriate. I. Introduction A. Background on... successor entity of ICE Trust (``ICE Trust'') will become Registered Clearing Agencies solely for the... rule amendments that, among other things, present novel or complex issues that require additional time...

30 CFR 250.803 - Additional production system requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ranges of pressure vessels at any time when there is a change in operating pressures that requires new... significant change in operating pressures. The most recent pressure-recorder charts used to determine... prominent place on the facility or structure. (v) For operations in subfreezing climates, the lessee shall...

Presidential Survival in Tough Times.

ERIC Educational Resources Information Center

Bowen, Raymond C.

Surviving the position of college president requires the development of a presidential survival kit filled with idiosyncratic items not normally associated with formal educational training. Strength, agility, control, and the ability to improvise are some of the talents required of a college president. In addition, the longevity and success of a…

76 FR 58495 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... required under the standards enable EPA to identify coating formulations manufactured, imported or... records. In addition, regulated entities are required to submit triennial reports of formulation data and... period. Burden means the total time, effort, or financial resources expended by persons to generate...

17 CFR 1.23 - Interest of futures commission merchant in segregated futures customer funds; additions and...

Code of Federal Regulations, 2014 CFR

2014-04-01

... any and all futures customers' accounts from becoming undersegregated at any time. (2) If a futures commission merchant discovers at any time that it is holding insufficient funds in segregated accounts to... with the segregated funds requirements at all times. Each futures commission merchant shall establish...

78 FR 71695 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-29

... inquiries and investigations. The current approach of requiring members to report the reference time instead... proposing amendments to the equity trade reporting rules relating to reporting (i) an additional time field for specified trades, (ii) execution time in milliseconds, (iii) reversals, (iv) trades executed on...

7 CFR 279.6 - Legal advice and extensions of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Legal advice and extensions of time. 279.6 Section 279.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE... discretion, additional time is required for the firm to fully present information in support of its position...

Modulation of Response Timing in ADHD, Effects of Reinforcement Valence and Magnitude

ERIC Educational Resources Information Center

Luman, Marjolein; Oosterlaan, Jaap; Sergeant, Joseph A.

2008-01-01

The present study investigated the impact of reinforcement valence and magnitude on response timing in children with ADHD. Children were required to estimate a 1-s interval, and both the median response time (response tendency) and the intrasubject-variability (response stability) were investigated. In addition, heart rate and skin conductance…

12 CFR 1238.8 - Additional implementing action.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Additional implementing action. 1238.8 Section 1238.8 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ENTITY REGULATIONS STRESS TESTING OF REGULATED..., require any regulated entity not subject to this part to conduct stress testing hereunder; and from time...

Capabilities needed for the next generation of thermo-hydraulic codes for use in real time applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arndt, S.A.

1997-07-01

The real-time reactor simulation field is currently at a crossroads in terms of the capability to perform real-time analysis using the most sophisticated computer codes. Current generation safety analysis codes are being modified to replace simplified codes that were specifically designed to meet the competing requirement for real-time applications. The next generation of thermo-hydraulic codes will need to have included in their specifications the specific requirement for use in a real-time environment. Use of the codes in real-time applications imposes much stricter requirements on robustness, reliability and repeatability than do design and analysis applications. In addition, the need for codemore » use by a variety of users is a critical issue for real-time users, trainers and emergency planners who currently use real-time simulation, and PRA practitioners who will increasingly use real-time simulation for evaluating PRA success criteria in near real-time to validate PRA results for specific configurations and plant system unavailabilities.« less

SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-14-259/260/261 AND MCU-14-315/316/317: APRIL AND MAY 2014 MONTHLY SAMPLES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fondeur, F.; Taylor-Pashow, K.

2014-08-05

SRNL received two sets of SHT samples (MCU-14-259/260/261 in April 2014 and MCU-14- 315/316/317 in May 2014) for analysis. The samples were analyzed for composition. Both samples have similar chemical composition. As with the previous solvent sample results, these analyses indicate that the solvent does not require Isopar® L trimming at this time. Since an addition of TiDG and MaxCalix to the SHT was added in early July 2014, the solvent does not require TiDG addition at this time. The current TiDG level (1.5 mM) is above the minimum recommended operating level of 1 mM.

Welfare Reform: With TANF Flexibility, States Vary in How They Implement Work Requirements and Time Limits. Report to the Chairman, Subcommittee on Human Resources, Committee on Ways and Means, House of Representatives.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC.

In this report, the General Accounting Office (GAO) examined how different states are implementing the work requirements and time limits called for by the Temporary Assistance for Needy Families (TANF) program. Data were collected from site visits in 4 states, telephone interviews with TANF officials in 8 additional states, and a survey…

78 FR 40351 - Procedural Rule To Establish Supervisory Authority Over Certain Nonbank Covered Persons Based on...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

...) Origination, brokerage, or servicing of loans secured by real estate for use by consumers primarily for... the construction of time limits, change of time limits, and effect of deadlines. Under the final rule... covered persons potentially subject to the final rule should not require additional time to come into...

75 FR 18413 - 2009-2010 Refuge-Specific Hunting and Sport Fishing Regulations-Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... near the time of acquisition. These regulations ensure that we make the determinations required by... result of this comment. Comment 2: The same commenter asked for an extension of time to further comment... maximize the time available for public review. We believe that a 30-day comment period, through the broader...

75 FR 1335 - Circular Welded Carbon Steel Pipes and Tubes from Taiwan; Extension of Time Limit for Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... DEPARTMENT OF COMMERCE International Trade Administration [A-583-008] Circular Welded Carbon Steel... review of the antidumping duty order on circular welded carbon steel pipes and tubes from Taiwan.\\1\\ On... review within the original time frame because we require additional time to obtain information from the...

20 CFR 411.180 - What is timely progress toward self-supporting employment?

Code of Federal Regulations, 2010 CFR

2010-04-01

... certificate or vocational or technical training that will enhance your ability to return to work. In addition...-secondary education requirement or vocational or technical training requirement in the applicable progress... this 12-month period; or (iv) You must have been enrolled in a vocational or technical training program...

40 CFR 60.5225 - What are the monitoring and calibration requirements for compliance with my operating limits?

Code of Federal Regulations, 2012 CFR

2012-07-01

... SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule... monitoring system according to your monitoring plan required under § 60.4880. Additionally: (i) For carrier gas flow rate monitors (for activated carbon injection), during the performance test conducted...

A Framework for Examining the Utility of Technology-Enhanced Items

ERIC Educational Resources Information Center

Russell, Michael

2016-01-01

Interest in and use of technology-enhanced items has increased over the past decade. Given the additional time required to administer many technology-enhanced items and the increased expense required to develop them, it is important for testing programs to consider the utility of technology-enhanced items. The Technology-Enhanced Item Utility…

20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.

Code of Federal Regulations, 2011 CFR

2011-04-01

... MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Requirements for Entitlement... years after the miner's death, whichever is later, or it is shown to the satisfaction of the... chapter), at the time of the miner's death. (c) In addition to the requirements set forth in paragraphs (a...

Relativistic Velocity Addition Law from Machine Gun Analogy

ERIC Educational Resources Information Center

Rothenstein, Bernhard; Popescu, Stefan

2009-01-01

Many derivations of the relativistic addition law of parallel velocities without use of the Lorentz transformations (LT) are known. Some of them are based on thought experiments that require knowledge of the time dilation and the length contraction effects. Other derivations involve the Doppler effect in the optic domain considered from three…

13 CFR 115.65 - General PSB procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... information for the term of the bond, plus such additional time as may be required to settle any claims of the Surety for reimbursement from SBA and to attempt salvage or other recovery, plus an additional 3 years... the Surety has established or added to a claim reserve; of the recovery of any amounts on the...

13 CFR 115.65 - General PSB procedures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... information for the term of the bond, plus such additional time as may be required to settle any claims of the Surety for reimbursement from SBA and to attempt salvage or other recovery, plus an additional 3 years... the Surety has established or added to a claim reserve; of the recovery of any amounts on the...

7 CFR 1435.102 - Eligibility requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Sugar Loan Program § 1435.102... sugar beets or sugarcane, including share rent landowners, at both the time of harvest and the time of... CFR part 718. (b) In addition to all other provisions of this part, a sugar beet or sugarcane...

7 CFR 1435.102 - Eligibility requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Sugar Loan Program § 1435.102... sugar beets or sugarcane, including share rent landowners, at both the time of harvest and the time of... CFR part 718. (b) In addition to all other provisions of this part, a sugar beet or sugarcane...

77 FR 4992 - Chlorinated Isocyanurates From the People's Republic of China: Extension of Time Limit for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... DEPARTMENT OF COMMERCE International Trade Administration [A-570-898] Chlorinated Isocyanurates... duty order on chlorinated isocyanurates (chlorinated isos) from the People's Republic of China (PRC... requires additional time to complete the preliminary results of the administrative review of chlorinated...

7 CFR 1435.102 - Eligibility requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Sugar Loan Program § 1435.102... sugar beets or sugarcane, including share rent landowners, at both the time of harvest and the time of... CFR part 718. (b) In addition to all other provisions of this part, a sugar beet or sugarcane...

7 CFR 1435.102 - Eligibility requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Sugar Loan Program § 1435.102... sugar beets or sugarcane, including share rent landowners, at both the time of harvest and the time of... CFR part 718. (b) In addition to all other provisions of this part, a sugar beet or sugarcane...

7 CFR 1435.102 - Eligibility requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Sugar Loan Program § 1435.102... sugar beets or sugarcane, including share rent landowners, at both the time of harvest and the time of... CFR part 718. (b) In addition to all other provisions of this part, a sugar beet or sugarcane...

78 FR 65180 - Airworthiness Directives; MD Helicopters, Inc., Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

... reducing the retirement life of each tail rotor blade (blade), performing a one-time visual inspection of... required reporting information to the FAA within 24 hours following the one-time inspection. Since we... pitting and the shot peen surface's condition in addition to cracks and corrosion, and adds certain part...

5 CFR 1631.8 - Prompt response.

Code of Federal Regulations, 2010 CFR

2010-01-01

... so advise the requester within 5 work days. The time limit for processing such a request will not... receipt of the request, unless additional time is required for one of the following reasons: (1) It is... the office processing the request (e.g., the record keeper); (2) It is necessary to search for...

Design and performance analysis of solid-propellant rocket motors using a simplified computer program

NASA Technical Reports Server (NTRS)

Sforzini, R. H.

1972-01-01

An analysis and a computer program are presented which represent a compromise between the more sophisticated programs using precise burning geometric relations and the textbook type of solutions. The program requires approximately 900 computer cards including a set of 20 input data cards required for a typical problem. The computer operating time for a single configuration is approximately 1 minute and 30 seconds on the IBM 360 computer. About l minute and l5 seconds of the time is compilation time so that additional configurations input at the same time require approximately 15 seconds each. The program uses approximately 11,000 words on the IBM 360. The program is written in FORTRAN 4 and is readily adaptable for use on a number of different computers: IBM 7044, IBM 7094, and Univac 1108.

A generic template for automated bioanalytical ligand-binding assays using modular robotic scripts in support of discovery biotherapeutic programs.

PubMed

Duo, Jia; Dong, Huijin; DeSilva, Binodh; Zhang, Yan J

2013-07-01

Sample dilution and reagent pipetting are time-consuming steps in ligand-binding assays (LBAs). Traditional automation-assisted LBAs use assay-specific scripts that require labor-intensive script writing and user training. Five major script modules were developed on Tecan Freedom EVO liquid handling software to facilitate the automated sample preparation and LBA procedure: sample dilution, sample minimum required dilution, standard/QC minimum required dilution, standard/QC/sample addition, and reagent addition. The modular design of automation scripts allowed the users to assemble an automated assay with minimal script modification. The application of the template was demonstrated in three LBAs to support discovery biotherapeutic programs. The results demonstrated that the modular scripts provided the flexibility in adapting to various LBA formats and the significant time saving in script writing and scientist training. Data generated by the automated process were comparable to those by manual process while the bioanalytical productivity was significantly improved using the modular robotic scripts.

49 CFR 231.2 - Hopper cars and high-side gondolas with fixed ends.

Code of Federal Regulations, 2010 CFR

2010-10-01

... which time they must be made to comply with the standards prescribed. (iv) Carriers are not required to... within 12 inches of a vertical plane parallel with end of car and passing through the inside face of... outer face of buffer block. (2) Carriers are not required to make changes to secure additional end...

26 CFR 1.7519-2T - Required payments-procedures and administration (temporary).

Code of Federal Regulations, 2011 CFR

2011-04-01

... should type or legibly print “zero” on the appropriate line of the prescribed form. (3) Time and place... termination of the section 444 election. (d) Negligence and fraud penalties made applicable. For purposes of section 6653, relating to additions to tax for negligence and fraud, any payment required by this section...

High School Graduation Requirements in a Time of College and Career Readiness. CSAI Report

ERIC Educational Resources Information Center

Center on Standards and Assessments Implementation, 2016

2016-01-01

Ensuring that students graduate high school prepared for college and careers has become a national priority in the last decade. To support this goal, states have adopted rigorous college and career readiness (CCR) standards in English language arts (ELA) and mathematics. Additionally, states have begun to require students to pass assessments, in…

On-board attitude determination for the Explorer Platform satellite

NASA Technical Reports Server (NTRS)

Jayaraman, C.; Class, B.

1992-01-01

This paper describes the attitude determination algorithm for the Explorer Platform satellite. The algorithm, which is baselined on the Landsat code, is a six-element linear quadratic state estimation processor, in the form of a Kalman filter augmented by an adaptive filter process. Improvements to the original Landsat algorithm were required to meet mission pointing requirements. These consisted of a more efficient sensor processing algorithm and the addition of an adaptive filter which acts as a check on the Kalman filter during satellite slew maneuvers. A 1750A processor will be flown on board the satellite for the first time as a coprocessor (COP) in addition to the NASA Standard Spacecraft Computer. The attitude determination algorithm, which will be resident in the COP's memory, will make full use of its improved processing capabilities to meet mission requirements. Additional benefits were gained by writing the attitude determination code in Ada.

31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

75 FR 60135 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; 1018-0092...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... governments. Respondent's Obligation: Required to obtain or retain a benefit. Frequency of Collection: On... of annual Completion time per Annual burden Activity respondents responses response hours 3-200-2... under the license, and any additional sale or transfer of the wildlife or wildlife products. In addition...

PFP Emergency Lighting Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

BUSCH, M.S.

2000-02-02

NFPA 101, section 5-9 mandates that, where required by building classification, all designated emergency egress routes be provided with adequate emergency lighting in the event of a normal lighting outage. Emergency lighting is to be arranged so that egress routes are illuminated to an average of 1.0 footcandle with a minimum at any point of 0.1 footcandle, as measured at floor level. These levels are permitted to drop to 60% of their original value over the required 90 minute emergency lighting duration after a power outage. The Plutonium Finishing Plant (PFP) has two designations for battery powered egress lights ''Emergencymore » Lights'' are those battery powered lights required by NFPA 101 to provide lighting along officially designated egress routes in those buildings meeting the correct occupancy requirements. Emergency Lights are maintained on a monthly basis by procedure ZSR-12N-001. ''Backup Lights'' are battery powered lights not required by NFPA, but installed in areas where additional light may be needed. The Backup Light locations were identified by PFP Safety and Engineering based on several factors. (1) General occupancy and type of work in the area. Areas occupied briefly during a shiftly surveillance do not require backup lighting while a room occupied fairly frequently or for significant lengths of time will need one or two Backup lights to provide general illumination of the egress points. (2) Complexity of the egress routes. Office spaces with a standard hallway/room configuration will not require Backup Lights while a large room with several subdivisions or irregularly placed rooms, doors, and equipment will require Backup Lights to make egress safer. (3) Reasonable balance between the safety benefits of additional lighting and the man-hours/exposure required for periodic light maintenance. In some plant areas such as building 236-Z, the additional maintenance time and risk of contamination do not warrant having Backup Lights installed in all rooms. Sufficient light for egress is provided by existing lights located in the hallways.« less

A Model of Batch Scheduling for a Single Batch Processor with Additional Setups to Minimize Total Inventory Holding Cost of Parts of a Single Item Requested at Multi-due-date

NASA Astrophysics Data System (ADS)

Hakim Halim, Abdul; Ernawati; Hidayat, Nita P. A.

2018-03-01

This paper deals with a model of batch scheduling for a single batch processor on which a number of parts of a single items are to be processed. The process needs two kinds of setups, i. e., main setups required before processing any batches, and additional setups required repeatedly after the batch processor completes a certain number of batches. The parts to be processed arrive at the shop floor at the times coinciding with their respective starting times of processing, and the completed parts are to be delivered at multiple due dates. The objective adopted for the model is that of minimizing total inventory holding cost consisting of holding cost per unit time for a part in completed batches, and that in in-process batches. The formulation of total inventory holding cost is derived from the so-called actual flow time defined as the interval between arrival times of parts at the production line and delivery times of the completed parts. The actual flow time satisfies not only minimum inventory but also arrival and delivery just in times. An algorithm to solve the model is proposed and a numerical example is shown.

HEVC real-time decoding

NASA Astrophysics Data System (ADS)

Bross, Benjamin; Alvarez-Mesa, Mauricio; George, Valeri; Chi, Chi Ching; Mayer, Tobias; Juurlink, Ben; Schierl, Thomas

2013-09-01

The new High Efficiency Video Coding Standard (HEVC) was finalized in January 2013. Compared to its predecessor H.264 / MPEG4-AVC, this new international standard is able to reduce the bitrate by 50% for the same subjective video quality. This paper investigates decoder optimizations that are needed to achieve HEVC real-time software decoding on a mobile processor. It is shown that HEVC real-time decoding up to high definition video is feasible using instruction extensions of the processor while decoding 4K ultra high definition video in real-time requires additional parallel processing. For parallel processing, a picture-level parallel approach has been chosen because it is generic and does not require bitstreams with special indication.

Space Transportation System Availability Relationships to Life Cycle Cost

NASA Technical Reports Server (NTRS)

Rhodes, Russel E.; Donahue, Benjamin B.; Chen, Timothy T.

2009-01-01

Future space transportation architectures and designs must be affordable. Consequently, their Life Cycle Cost (LCC) must be controlled. For the LCC to be controlled, it is necessary to identify all the requirements and elements of the architecture at the beginning of the concept phase. Controlling LCC requires the establishment of the major operational cost drivers. Two of these major cost drivers are reliability and maintainability, in other words, the system's availability (responsiveness). Potential reasons that may drive the inherent availability requirement are the need to control the number of unique parts and the spare parts required to support the transportation system's operation. For more typical space transportation systems used to place satellites in space, the productivity of the system will drive the launch cost. This system productivity is the resultant output of the system availability. Availability is equal to the mean uptime divided by the sum of the mean uptime plus the mean downtime. Since many operational factors cannot be projected early in the definition phase, the focus will be on inherent availability which is equal to the mean time between a failure (MTBF) divided by the MTBF plus the mean time to repair (MTTR) the system. The MTBF is a function of reliability or the expected frequency of failures. When the system experiences failures the result is added operational flow time, parts consumption, and increased labor with an impact to responsiveness resulting in increased LCC. The other function of availability is the MTTR, or maintainability. In other words, how accessible is the failed hardware that requires replacement and what operational functions are required before and after change-out to make the system operable. This paper will describe how the MTTR can be equated to additional labor, additional operational flow time, and additional structural access capability, all of which drive up the LCC. A methodology will be presented that provides the decision makers with the understanding necessary to place constraints on the design definition. This methodology for the major drivers will determine the inherent availability, safety, reliability, maintainability, and the life cycle cost of the fielded system. This methodology will focus on the achievement of an affordable, responsive space transportation system. It is the intent of this paper to not only provide the visibility of the relationships of these major attribute drivers (variables) to each other and the resultant system inherent availability, but also to provide the capability to bound the variables, thus providing the insight required to control the system's engineering solution. An example of this visibility is the need to provide integration of similar discipline functions to allow control of the total parts count of the space transportation system. Also, selecting a reliability requirement will place a constraint on parts count to achieve a given inherent availability requirement, or require accepting a larger parts count with the resulting higher individual part reliability requirements. This paper will provide an understanding of the relationship of mean repair time (mean downtime) to maintainability (accessibility for repair), and both mean time between failure (reliability of hardware) and the system inherent availability.

Delay to Reconstruction of the Adolescent Anterior Cruciate Ligament: The Socioeconomic Impact on Treatment.

PubMed

Newman, Justin T; Carry, Patrick M; Terhune, Elizabeth B; Spruiell, Murray; Heare, Austin; Mayo, Meredith; Vidal, Armando F

2014-08-01

A delay in pediatric and adolescent anterior cruciate ligament (ACL) reconstruction is associated with an increase in the number of concomitant meniscal and chondral injuries. Factors that contribute to this delay have not been well described. Socioeconomic and demographic factors are related to ACL surgery timing. Cohort study; Level of evidence, 3. All subjects who underwent primary ACL reconstruction at a single tertiary pediatric hospital between 2005 and 2012 were retrospectively reviewed. Variables included concomitant knee injuries (cartilage or meniscus injuries requiring additional operative treatment) and chronologic, demographic, and socioeconomic factors. Multivariable Cox proportional-hazards analyses were used to identify factors related to ACL surgery timing. The mean age of the 272 subjects was 15.2 ± 2.12 years. Time to surgery was significantly different among subjects who required multiple additional surgical procedures at time of ACL reconstruction (median, 3.3 months) compared with subjects with 1 (median, 2.0 months) or no additional injuries (median, 1.6 months). Subjects underwent ACL reconstruction significantly sooner if they were older at the time of injury (hazard ratio [HR], 1.2 per 1 year; 95% CI, 1.1-1.2; P < .0001) or were covered by a commercial insurance plan (HR, 2.0; 95% CI, 1.6-2.6; P < .0001). Median time to ACL surgery was 1.5 months (95% CI, 1.3-1.7) for subjects with commercial insurance plans compared with 3.0 months (95% CI, 2.3-3.3) for subjects with noncommercial insurance coverage. The risk of delayed ACL surgery was significantly higher among pediatric and adolescent subjects who were less affluent, who were covered by a noncommercial insurance plan, and who were younger. This study also confirms previous studies that have reported an association between a delay in ACL surgery and the presence of additional knee injuries requiring operative treatment, accentuating the importance of timely care. Access to care is a current area of research interest and health policy formation. Information in this arena drives 2 important aspects of health: most immediately, care provided to patients, and over a broader scope, the policy that directs health care. The orthopaedic surgeon should be aware of the association between socioeconomic and demographic factors and ACL surgery timing to optimize outcomes.

Supportability Technologies for Future Exploration Missions

NASA Technical Reports Server (NTRS)

Watson, Kevin; Thompson, Karen

2007-01-01

Future long-duration human exploration missions will be challenged by resupply limitations and mass and volume constraints. Consequently, it will be essential that the logistics footprint required to support these missions be minimized and that capabilities be provided to make them highly autonomous from a logistics perspective. Strategies to achieve these objectives include broad implementation of commonality and standardization at all hardware levels and across all systems, repair of failed hardware at the lowest possible hardware level, and manufacture of structural and mechanical replacement components as needed. Repair at the lowest hardware levels will require the availability of compact, portable systems for diagnosis of failures in electronic systems and verification of system functionality following repair. Rework systems will be required that enable the removal and replacement of microelectronic components with minimal human intervention to minimize skill requirements and training demand for crews. Materials used in the assembly of electronic systems (e.g. solders, fluxes, conformal coatings) must be compatible with the available repair methods and the spacecraft environment. Manufacturing of replacement parts for structural and mechanical applications will require additive manufacturing systems that can generate near-net-shape parts from the range of engineering alloys employed in the spacecraft structure and in the parts utilized in other surface systems. These additive manufacturing processes will need to be supported by real-time non-destructive evaluation during layer-additive processing for on-the-fly quality control. This will provide capabilities for quality control and may serve as an input for closed-loop process control. Additionally, non-destructive methods should be available for material property determination. These nondestructive evaluation processes should be incorporated with the additive manufacturing process - providing an in-process capability to ensure that material deposited during layer-additive processing meets required material property criteria.

31 CFR 203.20 - Investment account requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... obligations will be in the form of open-ended interest-bearing notes, or in the case of term investments, interest-bearing notes maintained for a predetermined period of time, and additions and reductions will be... in the form of interest-bearing notes payable upon a predetermined period of time not to exceed 90...

31 CFR 203.20 - Investment account requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... obligations will be in the form of open-ended interest-bearing notes, or in the case of term investments, interest-bearing notes maintained for a predetermined period of time, and additions and reductions will be... in the form of interest-bearing notes payable upon a predetermined period of time not to exceed 90...

The Effect of Amount and Timing of Human Resources Data on Subsystem Design.

ERIC Educational Resources Information Center

Meister, David; And Others

Human resources data (HRD) inputs often fail to influence system development. This study investigated the possibility that these inputs are sometimes deficient in quantity or timing. In addition, the effect upon design of different personnel quality and quantity requirements was analyzed. Equipment and HRD inputs which were produced during actual…

12 CFR 229.18 - Additional disclosure requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... consumer accounts a notice that sets forth the time periods applicable to the availability of funds deposited in a consumer account. (c) Automated teller machines. (1) A depositary bank shall post or provide... than two times each week, as described in § 229.19(a)(4), shall disclose at or on the ATM the days on...

12 CFR 229.18 - Additional disclosure requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... deposits to consumer accounts a notice that sets forth the time periods applicable to the availability of funds deposited in a consumer account. (c) Automated teller machines. (1) A depositary bank shall post... removed not more than two times each week, as described in § 229.19(a)(4), shall disclose at or on the ATM...

76 FR 60086 - Proposed Extension of the Approval of Information Collection Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-28

... of an employee and necessary accommodations; first aid and safety personnel may be informed, when... circumstances of the particular case. When an employee seeks leave for the first time for an FMLA-qualifying... qualifying exigency to certify the need for leave. In addition, the first time an employee requests leave for...

Checkpoint repair for high-performance out-of-order execution machines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwu, W.M.W.; Patt, Y.N.

Out-or-order execution and branch prediction are two mechanisms that can be used profitably in the design of supercomputers to increase performance. Proper exception handling and branch prediction miss handling in an out-of-order execution machine to require some kind of repair mechanism which can restore the machine to a known previous state. In this paper the authors present a class of repair mechanisms using the concept of checkpointing. The authors derive several properties of checkpoint repair mechanisms. In addition, they provide algorithms for performing checkpoint repair that incur little overhead in time and modest cost in hardware, which also require nomore » additional complexity or time for use with write-back cache memory systems than they do with write-through cache memory systems, contrary to statements made by previous researchers.« less

ANNIE - INTERACTIVE PROCESSING OF DATA BASES FOR HYDROLOGIC MODELS.

USGS Publications Warehouse

Lumb, Alan M.; Kittle, John L.

1985-01-01

ANNIE is a data storage and retrieval system that was developed to reduce the time and effort required to calibrate, verify, and apply watershed models that continuously simulate water quantity and quality. Watershed models have three categories of input: parameters to describe segments of a drainage area, linkage of the segments, and time-series data. Additional goals for ANNIE include the development of software that is easily implemented on minicomputers and some microcomputers and software that has no special requirements for interactive display terminals. Another goal is for the user interaction to be based on the experience of the user so that ANNIE is helpful to the inexperienced user and yet efficient and brief for the experienced user. Finally, the code should be designed so that additional hydrologic models can easily be added to ANNIE.

Polymerization-based signal amplification under ambient conditions with thirty-five second reaction times.

PubMed

Kaastrup, Kaja; Sikes, Hadley D

2012-10-21

Although polymerization-based amplification (PBA) has demonstrated promise as an inexpensive technique for use in molecular diagnostics, oxygen inhibition of radical photopolymerization has hindered its implementation in point-of-care devices. The addition of 0.3-0.7 μM eosin to an aqueous acrylate monomer solution containing a tertiary amine allows an interfacial polymerization reaction to proceed in air only near regions of a test surface where additional eosin initiators coupled to proteins have been localized as a function of molecular recognition events. The dose of light required for the reaction is inversely related to eosin concentration. This system achieves sensitivities comparable to those reported for inert gas-purged systems and requires significantly shorter reaction times. We provide several comparisons of this system with other implementations of polymerization-based amplification.

System-Level Logistics for Dual Purpose Canister Disposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalinina, Elena A.

2014-06-03

The analysis presented in this report investigated how the direct disposal of dual purpose canisters (DPCs) may be affected by the use of standard transportation aging and disposal canisters (STADs), early or late start of the repository, and the repository emplacement thermal power limits. The impacts were evaluated with regard to the availability of the DPCs for emplacement, achievable repository acceptance rates, additional storage required at an interim storage facility (ISF) and additional emplacement time compared to the corresponding repackaging scenarios, and fuel age at emplacement. The result of this analysis demonstrated that the biggest difference in the availability ofmore » UNF for emplacement between the DPC-only loading scenario and the DPCs and STADs loading scenario is for a repository start date of 2036 with a 6 kW thermal power limit. The differences are also seen in the availability of UNF for emplacement between the DPC-only loading scenario and the DPCs and STADs loading scenario for the alternative with a 6 kW thermal limit and a 2048 start date, and for the alternatives with a 10 kW thermal limit and 2036 and 2048 start dates. The alternatives with disposal of UNF in both DPCs and STADs did not require additional storage, regardless of the repository acceptance rate, as compared to the reference repackaging case. In comparison to the reference repackaging case, alternatives with the 18 kW emplacement thermal limit required little to no additional emplacement time, regardless of the repository start time, the fuel loading scenario, or the repository acceptance rate. Alternatives with the 10 kW emplacement thermal limit and the DPCs and STADs fuel loading scenario required some additional emplacement time. The most significant decrease in additional emplacement time occurred in the alternative with the 6 kW thermal limit and the 2036 repository starting date. The average fuel age at emplacement ranges from 46 to 88 years. The maximum fuel age at emplacement ranges from 81 to 146 years. The difference in the average and maximum age of fuel at emplacement between the DPC-only and the DPCs and STADs fuel loading scenarios becomes less significant as the repository thermal limit increases and as the repository start date increases. In general, the role of STADs is to store young (30 year or younger) high burnup (45 GWD/MTU or higher) fuel. Recommendations for future study include detailed evaluation of the feasible alternatives with regard to the costs and factors not considered in this analysis, such as worker dose, dose to members of the public, and economic benefits to host entities. It is also recommended to conduct an additional analysis to evaluate the assumption regarding the transportability and disposability of DPCs for the next iteration of the direct disposal of DPCs study.« less

Assessment of flat rolling theories for the use in a model-based controller for high-precision rolling applications

NASA Astrophysics Data System (ADS)

Stockert, Sven; Wehr, Matthias; Lohmar, Johannes; Abel, Dirk; Hirt, Gerhard

2017-10-01

In the electrical and medical industries the trend towards further miniaturization of devices is accompanied by the demand for smaller manufacturing tolerances. Such industries use a plentitude of small and narrow cold rolled metal strips with high thickness accuracy. Conventional rolling mills can hardly achieve further improvement of these tolerances. However, a model-based controller in combination with an additional piezoelectric actuator for high dynamic roll adjustment is expected to enable the production of the required metal strips with a thickness tolerance of +/-1 µm. The model-based controller has to be based on a rolling theory which can describe the rolling process very accurately. Additionally, the required computing time has to be low in order to predict the rolling process in real-time. In this work, four rolling theories from literature with different levels of complexity are tested for their suitability for the predictive controller. Rolling theories of von Kármán, Siebel, Bland & Ford and Alexander are implemented in Matlab and afterwards transferred to the real-time computer used for the controller. The prediction accuracy of these theories is validated using rolling trials with different thickness reduction and a comparison to the calculated results. Furthermore, the required computing time on the real-time computer is measured. Adequate results according the prediction accuracy can be achieved with the rolling theories developed by Bland & Ford and Alexander. A comparison of the computing time of those two theories reveals that Alexander's theory exceeds the sample rate of 1 kHz of the real-time computer.

Comparing bandwidth requirements for digital baseband signals.

NASA Technical Reports Server (NTRS)

Houts, R. C.; Green, T. A.

1972-01-01

This paper describes the relative bandwidth requirements of the common digital baseband signaling techniques used for data transmission. Bandwidth considerations include the percentage of total power in a properly encoded PN sequence passed at bandwidths of 0.5, 1, 2 and 3 times the reciprocal of the bit interval. The signals considered in this study are limited to the binary class. The study compares such signaling techniques as delay modulation, bipolar, biternary, duobinary, pair selected ternary and time polarity control in addition to the conventional NRZ, RZ and BI-phi schemes.

Critical care nursing interventions and the time required for their completion in Intensive Care Units: A Delphi study.

PubMed

Palomar-Aumatell, Xavier; Subirana-Casacuberta, Mireia; Mila-Villarroel, Raimon

2017-12-01

To determine which interventions within the Nursing Interventions Classification are most often applied in intensive care units and to validate the time required for each. A three-stage e-Delphi was conducted; 21 panelists were recruited, seven manager nurses and 14 clinical nurses with higher degrees and more than five years experience in intensive care nursing. The first round explored the most common interventions applied. Additionally, panelists were asked to propose others. In the second round, participants reflected on the interventions where no consensus was reached as well as to estimate the time required for each intervention. In the third, panelists were queried about the time required for the interventions for which consensus regarding the time was not reached. A total of 183 interventions were included; 50% of the "Physiological: Complex" domain. The list included 52 (90%) of the 58 "core interventions for critical care nursing" identified in the Nursing Interventions Classification. The time required for 89.1% of the interventions was the same as in the Nursing Interventions Classification seminal work recommendations. Results provide a clear picture of nursing activity in general intensive care units, allows to tailor the Nursing Intervetions Classification in Catalonia context and to confirm findings of previous studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

31 CFR 1020.320 - Reports by banks of suspicious transactions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... bank may delay filing a SAR for an additional 30 calendar days to identify a suspect. In no case shall... enforcement authority in addition to filing timely a SAR. (c) Exceptions. A bank is not required to file a SAR... authorized in this paragraph (e). For purposes of this paragraph (e) only, a SAR shall include any suspicious...

31 CFR 1020.320 - Reports by banks of suspicious transactions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... bank may delay filing a SAR for an additional 30 calendar days to identify a suspect. In no case shall... enforcement authority in addition to filing timely a SAR. (c) Exceptions. A bank is not required to file a SAR... authorized in this paragraph (e). For purposes of this paragraph (e) only, a SAR shall include any suspicious...

31 CFR 1020.320 - Reports by banks of suspicious transactions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... bank may delay filing a SAR for an additional 30 calendar days to identify a suspect. In no case shall... enforcement authority in addition to filing timely a SAR. (c) Exceptions. A bank is not required to file a SAR... authorized in this paragraph (e). For purposes of this paragraph (e) only, a SAR shall include any suspicious...

31 CFR 1020.320 - Reports by banks of suspicious transactions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... bank may delay filing a SAR for an additional 30 calendar days to identify a suspect. In no case shall... enforcement authority in addition to filing timely a SAR. (c) Exceptions. A bank is not required to file a SAR... authorized in this paragraph (e). For purposes of this paragraph (e) only, a SAR shall include any suspicious...

Immobilization techniques to avoid enzyme loss from oxidase-based biosensors: a one-year study.

PubMed

House, Jody L; Anderson, Ellen M; Ward, W Kenneth

2007-01-01

Continuous amperometric sensors that measure glucose or lactate require a stable sensitivity, and glutaraldehyde crosslinking has been used widely to avoid enzyme loss. Nonetheless, little data is published on the effectiveness of enzyme immobilization with glutaraldehyde. A combination of electrochemical testing and spectrophotometric assays was used to study the relationship between enzyme shedding and the fabrication procedure. In addition, we studied the relationship between the glutaraldehyde concentration and sensor performance over a period of one year. The enzyme immobilization process by glutaraldehyde crosslinking to glucose oxidase appears to require at least 24-hours at room temperature to reach completion. In addition, excess free glucose oxidase can be removed by soaking sensors in purified water for 20 minutes. Even with the addition of these steps, however, it appears that there is some free glucose oxidase entrapped within the enzyme layer which contributes to a decline in sensitivity over time. Although it reduces the ultimate sensitivity (probably via a change in the enzyme's natural conformation), glutaraldehyde concentration in the enzyme layer can be increased in order to minimize this instability. After exposure of oxidase enzymes to glutaraldehyde, effective crosslinking requires a rinse step and a 24-hour incubation step. In order to minimize the loss of sensor sensitivity over time, the glutaraldehyde concentration can be increased.

Design requirements and development of an airborne descent path definition algorithm for time navigation

NASA Technical Reports Server (NTRS)

Izumi, K. H.; Thompson, J. L.; Groce, J. L.; Schwab, R. W.

1986-01-01

The design requirements for a 4D path definition algorithm are described. These requirements were developed for the NASA ATOPS as an extension of the Local Flow Management/Profile Descent algorithm. They specify the processing flow, functional and data architectures, and system input requirements, and recommended the addition of a broad path revision (reinitialization) function capability. The document also summarizes algorithm design enhancements and the implementation status of the algorithm on an in-house PDP-11/70 computer. Finally, the requirements for the pilot-computer interfaces, the lateral path processor, and guidance and steering function are described.

Evaluation of DUII Sentencing Practices in Oregon.

DOT National Transportation Integrated Search

1997-10-01

Oregon law requires motorists driving under the influence of intoxicants (DUII) to be sentenced with some sanctions, and allows judges the use of additional sanctions. Sanctions including drug/alcohol treatment, jail time, community service, etc., ar...

17 CFR 140.96 - Delegation of authority to publish in the Federal Register.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., and rule amendments, when there exists novel or complex issues that require additional time to analyze, an inadequate explanation by the submitting registered entity, or a potential inconsistency with the...

17 CFR 140.96 - Delegation of authority to publish in the Federal Register.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., and rule amendments, when there exists novel or complex issues that require additional time to analyze, an inadequate explanation by the submitting registered entity, or a potential inconsistency with the...

14 CFR 91.1017 - Amending program manager's management specifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... applicant for the amendment to become effective, unless a shorter time is approved, in cases such as mergers, acquisitions of operational assets that require an additional showing of safety (for example, proving tests or...

Validating the Use of Deep Learning Neural Networks for Correction of Large Hydrometric Datasets

NASA Astrophysics Data System (ADS)

Frazier, N.; Ogden, F. L.; Regina, J. A.; Cheng, Y.

2017-12-01

Collection and validation of Earth systems data can be time consuming and labor intensive. In particular, high resolution hydrometric data, including rainfall and streamflow measurements, are difficult to obtain due to a multitude of complicating factors. Measurement equipment is subject to clogs, environmental disturbances, and sensor drift. Manual intervention is typically required to identify, correct, and validate these data. Weirs can become clogged and the pressure transducer may float or drift over time. We typically employ a graphical tool called Time Series Editor to manually remove clogs and sensor drift from the data. However, this process is highly subjective and requires hydrological expertise. Two different people may produce two different data sets. To use this data for scientific discovery and model validation, a more consistent method is needed to processes this field data. Deep learning neural networks have proved to be excellent mechanisms for recognizing patterns in data. We explore the use of Recurrent Neural Networks (RNN) to capture the patterns in the data over time using various gating mechanisms (LSTM and GRU), network architectures, and hyper-parameters to build an automated data correction model. We also explore the required amount of manually corrected training data required to train the network for reasonable accuracy. The benefits of this approach are that the time to process a data set is significantly reduced, and the results are 100% reproducible after training is complete. Additionally, we train the RNN and calibrate a physically-based hydrological model against the same portion of data. Both the RNN and the model are applied to the remaining data using a split-sample methodology. Performance of the machine learning is evaluated for plausibility by comparing with the output of the hydrological model, and this analysis identifies potential periods where additional investigation is warranted.

Real-Time Aerodynamic Flow and Data Visualization in an Interactive Virtual Environment

NASA Technical Reports Server (NTRS)

Schwartz, Richard J.; Fleming, Gary A.

2005-01-01

Significant advances have been made to non-intrusive flow field diagnostics in the past decade. Camera based techniques are now capable of determining physical qualities such as surface deformation, surface pressure and temperature, flow velocities, and molecular species concentration. In each case, extracting the pertinent information from the large volume of acquired data requires powerful and efficient data visualization tools. The additional requirement for real time visualization is fueled by an increased emphasis on minimizing test time in expensive facilities. This paper will address a capability titled LiveView3D, which is the first step in the development phase of an in depth, real time data visualization and analysis tool for use in aerospace testing facilities.

Neurosurgery simulation using non-linear finite element modeling and haptic interaction

NASA Astrophysics Data System (ADS)

Lee, Huai-Ping; Audette, Michel; Joldes, Grand R.; Enquobahrie, Andinet

2012-02-01

Real-time surgical simulation is becoming an important component of surgical training. To meet the realtime requirement, however, the accuracy of the biomechancial modeling of soft tissue is often compromised due to computing resource constraints. Furthermore, haptic integration presents an additional challenge with its requirement for a high update rate. As a result, most real-time surgical simulation systems employ a linear elasticity model, simplified numerical methods such as the boundary element method or spring-particle systems, and coarse volumetric meshes. However, these systems are not clinically realistic. We present here an ongoing work aimed at developing an efficient and physically realistic neurosurgery simulator using a non-linear finite element method (FEM) with haptic interaction. Real-time finite element analysis is achieved by utilizing the total Lagrangian explicit dynamic (TLED) formulation and GPU acceleration of per-node and per-element operations. We employ a virtual coupling method for separating deformable body simulation and collision detection from haptic rendering, which needs to be updated at a much higher rate than the visual simulation. The system provides accurate biomechancial modeling of soft tissue while retaining a real-time performance with haptic interaction. However, our experiments showed that the stability of the simulator depends heavily on the material property of the tissue and the speed of colliding objects. Hence, additional efforts including dynamic relaxation are required to improve the stability of the system.

Identification of periods of clear sky irradiance in time series of GHI measurements

DOE PAGES

Reno, Matthew J.; Hansen, Clifford W.

2016-01-18

In this study, we present a simple algorithm for identifying periods of time with broadband global horizontal irradiance (GHI) similar to that occurring during clear sky conditions from a time series of GHI measurements. Other available methods to identify these periods do so by identifying periods with clear sky conditions using additional measurements, such as direct or diffuse irradiance. Our algorithm compares characteristics of the time series of measured GHI with the output of a clear sky model without requiring additional measurements. We validate our algorithm using data from several locations by comparing our results with those obtained from amore » clear sky detection algorithm, and with satellite and ground-based sky imagery.« less

Identification of periods of clear sky irradiance in time series of GHI measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reno, Matthew J.; Hansen, Clifford W.

In this study, we present a simple algorithm for identifying periods of time with broadband global horizontal irradiance (GHI) similar to that occurring during clear sky conditions from a time series of GHI measurements. Other available methods to identify these periods do so by identifying periods with clear sky conditions using additional measurements, such as direct or diffuse irradiance. Our algorithm compares characteristics of the time series of measured GHI with the output of a clear sky model without requiring additional measurements. We validate our algorithm using data from several locations by comparing our results with those obtained from amore » clear sky detection algorithm, and with satellite and ground-based sky imagery.« less

Quantifying Economic and Environmental Impacts of Transportation Network Disruptions with Dynamic Traffic Simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shekar, Venkateswaran; Fiondella, Lance; Chatterjee, Samrat

Several transportation network vulnerability models have been proposed. However, most only consider disruptions as a static snapshot in time and the impact on total travel time. These approaches cannot consider the time-varying nature of travel demand nor other undesirable outcomes that follow from transportation network disruptions. This paper proposes an algorithmic approach to assess the vulnerability of a transportation network that considers the time-varying demand with an open source dynamic transportation simulation tool. The open source nature of the tool allows us to systematically consider many disruption scenarios and quantitatively compare their relative criticality. This is far more efficient thanmore » traditional approaches which would require days or weeks of a transportation engineers time to manually set up, run, and assess these simulations. In addition to travel time, we also collect statistics on additional fuel consumed and the corresponding carbon dioxide emissions. Our approach, thus provides a more systematic approach that is both time-varying and can consider additional negative consequences of disruptions for decision makers to evaluate.« less

Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes.

PubMed

Thurber, Brian W; Carmody, David; Tadie, Elizabeth C; Pastore, Ashley N; Dickens, Jazzmyne T; Wroblewski, Kristen E; Naylor, Rochelle N; Philipson, Louis H; Greeley, Siri Atma W

2015-07-01

Individuals with heterozygous activating mutations of the KCNJ11 gene encoding a subunit of the ATP-sensitive potassium channel (KATP) can usually be treated with oral sulfonylurea (SU) pills in lieu of insulin injections. The aim of this study was to test our hypothesis that younger age at the time of initiation of SU therapy is correlated with lower required doses of SU therapy, shorter transition time and decreased likelihood of requiring additional diabetes medications. We performed a retrospective cohort study using data on 58 individuals with neonatal diabetes due to KCNJ11 mutations identified through the University of Chicago Monogenic Diabetes Registry ( http://monogenicdiabetes.uchicago.edu/registry ). We assessed the influence of age at initiation of SU therapy on treatment outcomes. HbA1c fell from an average of 8.5% (69 mmol/mol) before transition to 6.2% (44 mmol/mol) after SU therapy (p < 0.001). Age of initiation of SU correlated with the dose (mg kg(-1) day(-1)) of SU required at follow-up (r = 0.80, p < 0.001). Similar associations were observed across mutation subtypes. Ten participants required additional glucose-lowering medications and all had initiated SU at age 13 years or older. No serious adverse events were reported. Earlier age at initiation of SU treatment is associated with improved response to SU therapy. Declining sensitivity to SU may be due to loss of beta cell mass over time in those treated with insulin. Our data support the need for early genetic diagnosis and appropriate personalised treatment in all cases of neonatal diabetes.

75 FR 5248 - Requirements and Procedures for Consumer Assistance To Recycle and Save Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... time will allow the public to benefit from the availability of lower cost used vehicle parts from... CARS program. The additional time would allow the public to benefit from the availability of lower cost... public benefit of having cheaper used vehicle parts from the vehicles traded in under the CARS program...

26 CFR 1.1445-3 - Adjustments to amount required to be withheld pursuant to withholding certificate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... applicant, by the 45th day after receipt of the application, that additional processing time will be... property interest to be transferred. The application must set forth information concerning the U.S. real... application, the time within which the Service must act upon the amended application shall be extended by 60...

In Swimming Branch, Identification of Family Burden of Families of Mentally Disabled Athletes

ERIC Educational Resources Information Center

Nacar, Eyyup; Karahuseyinoglu, M. Fatih; Karatas, Baykal; Altungul, Oguzhan

2017-01-01

The families of individuals with Down-syndrome, autism, and mental problem who need for special requirements experience physical problems, tiredness, and antisocial life, which bring additional cost to family budget, from time to time due to difficulties of their children The aim of this study is to identify family burdens charged by kids with…

The Experiences of Blacks Who Obtained Doctorates from Predominantly White Institutions

ERIC Educational Resources Information Center

Nickelberry, Tressie A.

2012-01-01

Being in a doctoral program requires a substantial amount of one's time, energy, and commitment. Doctoral students face many challenges while pursuing their degrees. For example, some may be on financial aid, work full-time, and/or have a family. While doctoral students face many hurdles, Black doctoral students face additional barriers. The…

Integrating O/S models during conceptual design, part 3

NASA Technical Reports Server (NTRS)

Ebeling, Charles E.

1994-01-01

Space vehicles, such as the Space Shuttle, require intensive ground support prior to, during, and after each mission. Maintenance is a significant part of that ground support. All space vehicles require scheduled maintenance to ensure operability and performance. In addition, components of any vehicle are not one-hundred percent reliable so they exhibit random failures. Once detected, a failure initiates unscheduled maintenance on the vehicle. Maintenance decreases the number of missions which can be completed by keeping vehicles out of service so that the time between the completion of one mission and the start of the next is increased. Maintenance also requires resources such as people, facilities, tooling, and spare parts. Assessing the mission capability and resource requirements of any new space vehicle, in addition to performance specification, is necessary to predict the life cycle cost and success of the vehicle. Maintenance and logistics support has been modeled by computer simulation to estimate mission capability and resource requirements for evaluation of proposed space vehicles. The simulation was written with Simulation Language for Alternative Modeling II (SLAM II) for execution on a personal computer. For either one or a fleet of space vehicles, the model simulates the preflight maintenance checks, the mission and return to earth, and the post flight maintenance in preparation to be sent back into space. THe model enables prediction of the number of missions possible and vehicle turn-time (the time between completion of one mission and the start of the next) given estimated values for component reliability and maintainability. The model also facilitates study of the manpower and vehicle requirements for the proposed vehicle to meet its desired mission rate. This is the 3rd part of a 3 part technical report.

Production scheduling with discrete and renewable additional resources

NASA Astrophysics Data System (ADS)

Kalinowski, K.; Grabowik, C.; Paprocka, I.; Kempa, W.

2015-11-01

In this paper an approach to planning of additional resources when scheduling operations are discussed. The considered resources are assumed to be discrete and renewable. In most research in scheduling domain, the basic and often the only type of regarded resources is a workstation. It can be understood as a machine, a device or even as a separated space on the shop floor. In many cases, during the detailed scheduling of operations the need of using more than one resource, required for its implementation, can be indicated. Resource requirements for an operation may relate to different resources or resources of the same type. Additional resources are most often referred to these human resources, tools or equipment, for which the limited availability in the manufacturing system may have an influence on the execution dates of some operations. In the paper the concept of the division into basic and additional resources and their planning method was shown. A situation in which sets of basic and additional resources are not separable - the same additional resource may be a basic resource for another operation is also considered. Scheduling of operations, including greater amount of resources can cause many difficulties, depending on whether the resource is involved in the entire time of operation, only in the selected part(s) of operation (e.g. as auxiliary staff at setup time) or cyclic - e.g. when an operator supports more than one machine, or supervises the execution of several operations. For this reason the dates and work times of resources participation in the operation can be different. Presented issues are crucial when modelling of production scheduling environment and designing of structures for the purpose of scheduling software development.

75 FR 48629 - Electronic Tariff Filing System (ETFS)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-11

...In this document, the Federal Communications Commission (Commission) seeks comment on extending the electronic tariff filing requirement for incumbent local exchange carriers to all carriers that file tariffs and related documents. Additionally, the Commission seeks comment on the appropriate time frame for implementing this proposed requirement. The Commission also seeks comment on the proposal that the Chief of the Wireline Competition Bureau administer the adoption of this extended electronic filing requirement. Also, the Commission seeks comment on proposed rule changes to implement mandatory electronic tariff filing.

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

DEET

MedlinePlus

... of designated critical habitat for all currently registered uses of DEET. EPA issued an Interim Decision for DEET in September 2014. We concluded that: no additional data are required at this time; and no changes to the affected registrations or their labeling are ...

Ultrasonication aided in-situ transesterification of microbial lipids to biodiesel.

PubMed

Zhang, Xiaolei; Yan, Song; Tyagi, Rajeshwar Dayal; Surampalli, Rao Y; Valéro, Jose R

2014-10-01

In-situ transesterification of microbial lipid to biodiesel has been paid substantial attention due to the fact that the lipid extraction and transesterification can be conducted in one-stage process. To improve the feasibility of in-situ transesterification, ultrasonication was employed to reduce methanol requirement and reaction time. The results showed that the use of ultrasonication could achieve high conversion of lipid to FAMEs (92.1% w lipid conversion/w total lipids) with methanol to lipid molar ratio 60:1 and NaOH addition 1% w/w lipid in 20 min, while methanol to lipid molar ratio 360:1, NaOH addition 1% w/w lipid, and reaction time 12h was required to obtain similar yield in in-situ transesterification without ultrasonication. The compositions of FAMEs obtained in case of ultrasonication aided in-situ transesterification were similar as that of two-stage extraction followed by transesterification processes. Copyright © 2014. Published by Elsevier Ltd.

Microbiological and Corrosivity Characterizations of Biodiesels and Advanced Diesel Fuels

DTIC Science & Technology

2009-01-01

hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...including corrosion inhibitors. Requirements for microbial growth are water and nutrients. In addition to carbon , all organisms require nitrogen...microbial mineralization of fuel to generate a water phase for further proliferation. For example, Cladosporium resinae grew in 80 mg water per liter

The use of AntiMisting Kerosene (AMK) in turbojet engines

NASA Technical Reports Server (NTRS)

Schmidt, H. W.

1981-01-01

The effect of antimisting kerosene (AMK) flow characteristics on fan jet engines and the impact of degradation requirements on the fuel system was evaluated. It was determined from the present program that AMK fuel cannot be used without predegradation, although some degradation occurs throughout the fuel feed system, expecially in the fuel pumps. There is a tendency toward FM-9 AMK additive agglomeration and gel formation when the liquid flows at a critical velocity through very small passages. The data indicate this phenomenon to be a function of the degree of degradation, the passage size, the differential pressure, the fluid temperature, and the accumulated flow time. Additionally, test results indicate that the long term cumulative effects of this phenomenon may require more degradation than the theoretical requirement determined from short term tests.

Implications caused by SARex on the implementation of the IMO polar code on survival at sea

NASA Astrophysics Data System (ADS)

Solberg, K. E.

2017-12-01

The International Code for Ships Operating in Polar waters goes into effect on 01 January 2018 for all ships. This puts additional strain on vessel owners and operators as they will have to comply with an additional set of requirements. This includes the functional requirement of a minimum of 5 days survival time. The SARex exercise has elaborated on the issue of survival in close cooperation with the different stakeholders associated with the marine industry. Being an objective third party is important when organizing and executing these activities as all of the stakeholders has different agendas and priorities. Developing sustainable solutions is a balancing act, incorporating economic and political aspects as well as technology and requires a mutual common understanding of the mechanism involved.

Reticles, write time, and the need for speed

NASA Astrophysics Data System (ADS)

Ackmann, Paul W.; Litt, Lloyd C.; Ning, Guo Xiang

2014-10-01

Historical data indicates reticle write times are increasing node-to-node. The cost of mask sets is increasing driven by the tighter requirements and more levels. The regular introduction of new generations of mask patterning tools with improved performance is unable to fully compensate for the increased data and complexity required. Write time is a primary metric that drives mask fabrication speed. Design (Raw data) is only the first step in the process and many interactions between mask and wafer technology such as OPC used, OPC efficiency for writers, fracture engines, and actual field size used drive total write time. Yield, technology, and inspection rules drive the remaining raw cycle time. Yield can be even more critical for speed of delivery as it drives re-writes and wasted time. While intrinsic process yield is important, repair capability is the reason mask delivery is still able to deliver 100% good reticles to the fab. Advanced nodes utilizing several layers of multiple patterning may require mask writer tool dedication to meet image placement specifications. This will increase the effective mask cycle time for a layer mask set and drive the need for additional mask write capability in order to deliver masks at the rate required by the wafer fab production schedules.

Real-Time Simulation of Ares I Launch Vehicle

NASA Technical Reports Server (NTRS)

Tobbe, Patrick; Matras, Alex; Wilson, Heath; Alday, Nathan; Walker, David; Betts, Kevin; Hughes, Ryan; Turbe, Michael

2009-01-01

The Ares Real-Time Environment for Modeling, Integration, and Simulation (ARTEMIS) has been developed for use by the Ares I launch vehicle System Integration Laboratory (SIL) at the Marshall Space Flight Center (MSFC). The primary purpose of the Ares SIL is to test the vehicle avionics hardware and software in a hardware-in-the-loop (HWIL) environment to certify that the integrated system is prepared for flight. ARTEMIS has been designed to be the real-time software backbone to stimulate all required Ares components through high-fidelity simulation. ARTEMIS has been designed to take full advantage of the advances in underlying computational power now available to support HWIL testing. A modular real-time design relying on a fully distributed computing architecture has been achieved. Two fundamental requirements drove ARTEMIS to pursue the use of high-fidelity simulation models in a real-time environment. First, ARTEMIS must be used to test a man-rated integrated avionics hardware and software system, thus requiring a wide variety of nominal and off-nominal simulation capabilities to certify system robustness. The second driving requirement - derived from a nationwide review of current state-of-the-art HWIL facilities - was that preserving digital model fidelity significantly reduced overall vehicle lifecycle cost by reducing testing time for certification runs and increasing flight tempo through an expanded operational envelope. These two driving requirements necessitated the use of high-fidelity models throughout the ARTEMIS simulation. The nature of the Ares mission profile imposed a variety of additional requirements on the ARTEMIS simulation. The Ares I vehicle is composed of multiple elements, including the First Stage Solid Rocket Booster (SRB), the Upper Stage powered by the J- 2X engine, the Orion Crew Exploration Vehicle (CEV) which houses the crew, the Launch Abort System (LAS), and various secondary elements that separate from the vehicle. At launch, the integrated vehicle stack is composed of these stages, and throughout the mission, various elements separate from the integrated stack and tumble back towards the earth. ARTEMIS must be capable of simulating the integrated stack through the flight as well as propagating each individual element after separation. In addition, abort sequences can lead to other unique configurations of the integrated stack as the timing and sequence of the stage separations are altered.

Some evidentiary considerations for physician billing.

PubMed

Rooks, Franklin J

2011-01-01

In a criminal prosecution for medical billing fraud alleging up-coding and overbilling, the government's evidence may encompass the practice's entire billings and draw inferences from them. In addition, fraud may be demonstrated through statistical analysis comparing a physician's billings relative to other providers of the same specialty. The Federal Rules of Evidence govern the admissibility of evidence during a trial, to provide fairness for both the prosecution and the defense. Physicians and practice managers should be well versed in the billing requirements and particularly careful when CPT codes are expressed in terms of "required times" as opposed to "typical times."

Simulation Evaluation of Pilot Inputs for Real Time Modeling During Commercial Flight Operations

NASA Technical Reports Server (NTRS)

Martos, Borja; Ranaudo, Richard; Oltman, Ryan; Myhre, Nick

2017-01-01

Aircraft dynamics characteristics can only be identified from flight data when the aircraft dynamics are excited sufficiently. A preliminary study was conducted into what types and levels of manual piloted control excitation would be required for accurate Real-Time Parameter IDentification (RTPID) results by commercial airline pilots. This includes assessing the practicality for the pilot to provide this excitation when cued, and to further understand if pilot inputs during various phases of flight provide sufficient excitation naturally. An operationally representative task was evaluated by 5 commercial airline pilots using the NASA Ice Contamination Effects Flight Training Device (ICEFTD). Results showed that it is practical to use manual pilot inputs only as a means of achieving good RTPID in all phases of flight and in flight turbulence conditions. All pilots were effective in satisfying excitation requirements when cued. Much of the time, cueing was not even necessary, as just performing the required task provided enough excitation for accurate RTPID estimation. Pilot opinion surveys reported that the additional control inputs required when prompted by the excitation cueing were easy to make, quickly mastered, and required minimal training.

5 CFR 1312.36 - Appeal procedure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES CLASSIFICATION, DOWNGRADING... is declassified and otherwise releasable. If continued classification is required, the requestor... normally be made within 60 working days following receipt. If additional time is needed, the requestor will...

5 CFR 1312.36 - Appeal procedure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES CLASSIFICATION, DOWNGRADING... is declassified and otherwise releasable. If continued classification is required, the requestor... normally be made within 60 working days following receipt. If additional time is needed, the requestor will...

77 FR 4848 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-31

... unavailable due to sickness, vacation or other reason, the ATP Holder is required to pay for an additional ATP... such time as the absent Floor Market Maker returns. When a Floor Market Maker is or will be absent, an... filed, or such shorter time as the Commission may designate, if consistent with the protection of...

7 CFR 500.22 - Fees and conditions for use of facilities and grounds.

Code of Federal Regulations, 2013 CFR

2013-01-01

... is committed, including time used to set up before and clean up after an event. For after-hours usage of sites or facilities, an additional $40/hour will be added for supervision for each required staff... the planned use or event. (4) A 50 percent non-refundable deposit will be due at the time of a booking...

7 CFR 500.22 - Fees and conditions for use of facilities and grounds.

Code of Federal Regulations, 2014 CFR

2014-01-01

... is committed, including time used to set up before and clean up after an event. For after-hours usage of sites or facilities, an additional $40/hour will be added for supervision for each required staff... the planned use or event. (4) A 50 percent non-refundable deposit will be due at the time of a booking...

7 CFR 500.22 - Fees and conditions for use of facilities and grounds.

Code of Federal Regulations, 2011 CFR

2011-01-01

... is committed, including time used to set up before and clean up after an event. For after-hours usage of sites or facilities, an additional $40/hour will be added for supervision for each required staff... the planned use or event. (4) A 50 percent non-refundable deposit will be due at the time of a booking...

7 CFR 500.22 - Fees and conditions for use of facilities and grounds.

Code of Federal Regulations, 2012 CFR

2012-01-01

... is committed, including time used to set up before and clean up after an event. For after-hours usage of sites or facilities, an additional $40/hour will be added for supervision for each required staff... the planned use or event. (4) A 50 percent non-refundable deposit will be due at the time of a booking...

Predictable repair of provisional restorations.

PubMed

Hammond, Barry D; Cooper, Jeril R; Lazarchik, David A

2009-01-01

The importance of provisional restorations is often downplayed, as they are thought of by some as only "temporaries." As a result, a less-than-ideal provisional is sometimes fabricated, in part because of the additional chair time required to make provisional modifications when using traditional techniques. Additionally, in many dental practices, these provisional restorations are often fabricated by auxillary personnel who may not be as well trained in the fabrication process. Because provisionals play an important role in achieving the desired final functional and esthetic result, a high-quality provisional restoration is essential to fabricating a successful definitive restoration. This article describes a method for efficiently and predictably repairing both methacrylate and bis-acryl provisional restorations using flowable composite resin. By use of this relatively simple technique, provisional restorations can now be modified or repaired in a timely and productive manner to yield an exceptional result. Successful execution of esthetic and restorative dentistry requires attention to detail in every aspect of the case. Fabrication of high-quality provisional restorations can, at times, be challenging and time consuming. The techniques for optimizing resin provisional restorations as described in this paper are pragmatic and will enhance the delivery of dental treatment.

Interactive real time flow simulations

NASA Technical Reports Server (NTRS)

Sadrehaghighi, I.; Tiwari, S. N.

1990-01-01

An interactive real time flow simulation technique is developed for an unsteady channel flow. A finite-volume algorithm in conjunction with a Runge-Kutta time stepping scheme was developed for two-dimensional Euler equations. A global time step was used to accelerate convergence of steady-state calculations. A raster image generation routine was developed for high speed image transmission which allows the user to have direct interaction with the solution development. In addition to theory and results, the hardware and software requirements are discussed.

Real-time and high accuracy frequency measurements for intermediate frequency narrowband signals

NASA Astrophysics Data System (ADS)

Tian, Jing; Meng, Xiaofeng; Nie, Jing; Lin, Liwei

2018-01-01

Real-time and accurate measurements of intermediate frequency signals based on microprocessors are difficult due to the computational complexity and limited time constraints. In this paper, a fast and precise methodology based on the sigma-delta modulator is designed and implemented by first generating the twiddle factors using the designed recursive scheme. This scheme requires zero times of multiplications and only half amounts of addition operations by using the discrete Fourier transform (DFT) and the combination of the Rife algorithm and Fourier coefficient interpolation as compared with conventional methods such as DFT and Fast Fourier Transform. Experimentally, when the sampling frequency is 10 MHz, the real-time frequency measurements with intermediate frequency and narrowband signals have a measurement mean squared error of ±2.4 Hz. Furthermore, a single measurement of the whole system only requires approximately 0.3 s to achieve fast iteration, high precision, and less calculation time.

Measuring Attention in Rodents: Comparison of a Modified Signal Detection Task and the 5-Choice Serial Reaction Time Task

PubMed Central

Turner, Karly M.; Peak, James; Burne, Thomas H. J.

2016-01-01

Neuropsychiatric research has utilized cognitive testing in rodents to improve our understanding of cognitive deficits and for preclinical drug development. However, more sophisticated cognitive tasks have not been as widely exploited due to low throughput and the extensive training time required. We developed a modified signal detection task (SDT) based on the growing body of literature aimed at improving cognitive testing in rodents. This study directly compares performance on the modified SDT with a traditional test for measuring attention, the 5-choice serial reaction time task (5CSRTT). Adult male Sprague-Dawley rats were trained on either the 5CSRTT or the SDT. Briefly, the 5CSRTT required rodents to pay attention to a spatial array of five apertures and respond with a nose poke when an aperture was illuminated. The SDT required the rat to attend to a light panel and respond either left or right to indicate the presence of a signal. In addition, modifications were made to the reward delivery, timing, control of body positioning, and the self-initiation of trials. It was found that less training time was required for the SDT, with both sessions to criteria and daily session duration significantly reduced. Rats performed with a high level of accuracy (>87%) on both tasks, however omissions were far more frequent on the 5CSRTT. The signal duration was reduced on both tasks as a manipulation of task difficulty relevant to attention and a similar pattern of decreasing accuracy was observed on both tasks. These results demonstrate some of the advantages of the SDT over the traditional 5CSRTT as being higher throughput with reduced training time, fewer omission responses and their body position was controlled at stimulus onset. In addition, rats performing the SDT had comparable high levels of accuracy. These results highlight the differences and similarities between the 5CSRTT and a modified SDT as tools for assessing attention in preclinical animal models. PMID:26834597

U.S. Army Military Police: The Force of Choice for Defense Support to Civil Authorities

DTIC Science & Technology

2014-05-22

nearly identical to the qualifications and standards required for first responders and emergency managers. Additionally, within a military police...and first responders requires trust and a common professional language. Through the Police Officer Standards and Training program and Federal Law...away some of their own precious free time to review my work. The excellent research librarians at the Combined Arms Research Library were invaluable

Towards a Cloud Computing Environment: Near Real-time Cloud Product Processing and Distribution for Next Generation Satellites

NASA Astrophysics Data System (ADS)

Nguyen, L.; Chee, T.; Minnis, P.; Palikonda, R.; Smith, W. L., Jr.; Spangenberg, D.

2016-12-01

The NASA LaRC Satellite ClOud and Radiative Property retrieval System (SatCORPS) processes and derives near real-time (NRT) global cloud products from operational geostationary satellite imager datasets. These products are being used in NRT to improve forecast model, aircraft icing warnings, and support aircraft field campaigns. Next generation satellites, such as the Japanese Himawari-8 and the upcoming NOAA GOES-R, present challenges for NRT data processing and product dissemination due to the increase in temporal and spatial resolution. The volume of data is expected to increase to approximately 10 folds. This increase in data volume will require additional IT resources to keep up with the processing demands to satisfy NRT requirements. In addition, these resources are not readily available due to cost and other technical limitations. To anticipate and meet these computing resource requirements, we have employed a hybrid cloud computing environment to augment the generation of SatCORPS products. This paper will describe the workflow to ingest, process, and distribute SatCORPS products and the technologies used. Lessons learn from working on both AWS Clouds and GovCloud will be discussed: benefits, similarities, and differences that could impact decision to use cloud computing and storage. A detail cost analysis will be presented. In addition, future cloud utilization, parallelization, and architecture layout will be discussed for GOES-R.

Immobilization Techniques to Avoid Enzyme Loss from Oxidase-Based Biosensors: A One-Year Study

PubMed Central

House, Jody L.; Anderson, Ellen M.; Ward, W. Kenneth

2007-01-01

Background Continuous amperometric sensors that measure glucose or lactate require a stable sensitivity, and glutaraldehyde crosslinking has been used widely to avoid enzyme loss. Nonetheless, little data is published on the effectiveness of enzyme immobilization with glutaraldehyde. Methods A combination of electrochemical testing and spectrophotometric assays was used to study the relationship between enzyme shedding and the fabrication procedure. In addition, we studied the relationship between the glutaraldehyde concentration and sensor performance over a period of one year. Results The enzyme immobilization process by glutaraldehyde crosslinking to glucose oxidase appears to require at least 24-hours at room temperature to reach completion. In addition, excess free glucose oxidase can be removed by soaking sensors in purified water for 20 minutes. Even with the addition of these steps, however, it appears that there is some free glucose oxidase entrapped within the enzyme layer which contributes to a decline in sensitivity over time. Although it reduces the ultimate sensitivity (probably via a change in the enzyme's natural conformation), glutaraldehyde concentration in the enzyme layer can be increased in order to minimize this instability. Conclusions After exposure of oxidase enzymes to glutaraldehyde, effective crosslinking requires a rinse step and a 24-hour incubation step. In order to minimize the loss of sensor sensitivity over time, the glutaraldehyde concentration can be increased. PMID:19888375

A Web-based Multimedia Program Before Colonoscopy Increased Knowledge and Decreased Anxiety, Sedation Requirement, and Procedure Time.

PubMed

Parker, Siddhartha; Zipursky, Jonathan; Ma, Helen; Baumblatt, Geri-Lynn; Siegel, Corey A

2018-07-01

Assess the impact of a web-based multimedia patient engagement program on patient anxiety, perception and knowledge about the colonoscopy in addition to procedure outcomes. The success of patients coming for a colonoscopy for colorectal cancer screening is dependent in part on patients' understanding of the preparation and of the procedure. Patients were randomized to use either our institution's standard preprocedure colonoscopy packet or a web-based multimedia patient engagement program (Emmi Solutions) before their scheduled procedure. On the day of colonoscopy, all participants completed a survey including questions to assess knowledge and perception of colonoscopy, in addition to the State Trait Anxiety Inventory. We also collected procedure data including medication doses and procedure time. Patients in the experimental group correctly answered knowledge questions (82%) more often than the control group (74%) (P=0.0003). More than half (58%) of patients in the experimental group felt this intervention reduced their anxiety about the procedure, and the State Trait Anxiety Inventory anxiety score was lower in the experimental group (P=0.026). Patients who viewed the program required less midazolam (3.66 vs. 4.46 mg, P=0.0035) and total procedure time was shorter (24.8 vs. 29 min, P=0.024). A web-based multimedia patient engagement program watched before colonoscopy decreased patient anxiety, medication requirements, and procedure time while increasing knowledge. This intervention could help patients understand and feel more comfortable about colonoscopy leading to increased screening rates while increasing efficiency and decreasing recovery time.

Gateway Portal

DTIC Science & Technology

2004-03-01

using standard Internet technologies with no additional client software required. Furthermore, using a portable...Wilkerson Computational and Information Sciences Directorate, ARL Approved for public release... information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and

Lead Time Study,

DTIC Science & Technology

1982-05-01

1979, the number of titanium fabrications dropped from 16 to 4, primarily because of the sponge shortage and EPA and OSHA requirements. Non-military...East - Taiwan, Korea, Singapore, Malaysia and Hong Kong. In addition, a significant amount of ceramic parts, lead frames and high technology

Advanced order management in ERM systems: the tic-tac-toe algorithm

NASA Astrophysics Data System (ADS)

Badell, Mariana; Fernandez, Elena; Puigjaner, Luis

2000-10-01

The concept behind improved enterprise resource planning systems (ERP) systems is the overall integration of the whole enterprise functionality into the management systems through financial links. Converting current software into real management decision tools requires crucial changes in the current approach to ERP systems. This evolution must be able to incorporate the technological achievements both properly and in time. The exploitation phase of plants needs an open web-based environment for collaborative business-engineering with on-line schedulers. Today's short lifecycles of products and processes require sharp and finely tuned management actions that must be guided by scheduling tools. Additionally, such actions must be able to keep track of money movements related to supply chain events. Thus, the necessary outputs require financial-production integration at the scheduling level as proposed in the new approach of enterprise management systems (ERM). Within this framework, the economical analysis of the due date policy and its optimization become essential to manage dynamically realistic and optimal delivery dates with price-time trade-off during the marketing activities. In this work we propose a scheduling tool with web-based interface conducted by autonomous agents when precise economic information relative to plant and business actions and their effects are provided. It aims to attain a better arrangement of the marketing and production events in order to face the bid/bargain process during e-commerce. Additionally, management systems require real time execution and an efficient transaction-oriented approach capable to dynamically adopt realistic and optimal actions to support marketing management. To this end the TicTacToe algorithm provides sequence optimization with acceptable tolerances in realistic time.

Rapid on-site assessment of specimens by biomedical scientists improves the quality of head and neck fine needle aspiration cytology.

PubMed

Breeze, J; Poller, D N; Gibson, D; Tilley, E A; Cooke, L; Soar, E; Repanos, C

2014-10-01

Immediate rapid on-site assessment (ROSA) of fine needle aspiration cytology (FNAC) specimens by biomedical scientists (BMS), the UK equivalent of cytotechnologists, or by pathologists may improve specimen quality and cellular adequacy rates for lymph node, head and neck and thyroid FNAC. The aim of this study was to evaluate the effect of introducing ROSA by BMS in an outpatient clinic setting. The adequacy rate and sensitivity of histological diagnosis for lymph node, thyroid and salivary gland FNAC samples were determined before and after the introduction of BMS ROSA. The additional financial costs and time required to perform this service were also estimated. Thirty-one patients underwent ultrasound (US)-guided FNAC with ROSA and 151 without. ROSA reduced the number of FNAC insufficient in quality for diagnosis from 43% to 19% (P = 0.0194). The estimated additional cost for pathology per patient for ROSA was between £52.05 and £70.74, equivalent to €65.40/US $83.90 and €88.89/US $114.0, respectively, an increase of between 28% and 49% from the original cost. ROSA necessitated an additional 6 minutes clinic time per patient, reducing the number of patients that could be seen in an average clinic from 13 to 10 as well as requiring increased laboratory time for FNAC slide assessment. ROSA by suitably trained biomedical scientists and with appropriate consultant pathologist support can improve the quality of FNAC sampling for head and neck lesions. Although ROSA resulted in both additional financial and time costs, these are more than likely to be offset by a reduction in patients returning to clinic for repeat FNAC or undergoing unnecessary surgery. © 2013 John Wiley & Sons Ltd.

Ketamine versus alfentanil combined with propofol for sedation in colonoscopy procedures: a randomized prospective study.

PubMed

Türk, Hacer Şebnem; Aydoğmuş, Meltem; Ünsal, Oya; Işıl, Canan Tülay; Citgez, Bülent; Oba, Sibel; Açık, Mehmet Eren

2014-12-01

Different drug combinations are used for sedation in colonoscopy procedures. A ketamine-propofol (ketofol) mixture provides effective sedation and has minimal adverse effects. Alfentanil also provides anesthesia for short surgical procedures by incremental injection as an adjunct. However, no study has investigated the use of ketofol compared with an opioid-propofol combination in colonoscopic procedures. A total of 70 patients, ASA physical status I-II, scheduled to undergo elective colonoscopy, were enrolled in this prospective randomized study and allocated to two groups. After premedication, sedation induction was performed with 0.5 mg/kg ketamine +1 mg/kg propofol in Group KP, and 10 mg/kg alfentanil +1 mg/kg propofol in Group AP. Propofol was added when required. Demographic data, colonoscopy duration, recovery time, discharge time, mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation, Ramsey Sedation Scale values, colonoscopy patients' satisfaction scores, and complications were recorded. The need for additional propofol doses was significantly higher in Group AP than in Group KP. MAP at minute 1 and 5, Ramsey Sedation Scale at minute 5, and discharge time were significantly higher in Group KP than in Group AP. Additional propofol doses and total propofol dose were significantly lower in Group KP than in Group AP. Ketofol provided better hemodynamic stability and quality of sedation compared with alfentanil-propofol combination in elective colonoscopy, and required fewer additional propofol; however, it prolonged discharge time. Both combinations can safely be used in colonoscopy sedation.

Ultrafast detection in particle physics and positron emission tomography using SiPMs

NASA Astrophysics Data System (ADS)

Dolenec, R.; Korpar, S.; Križan, P.; Pestotnik, R.

2017-12-01

Silicon photomultiplier (SiPM) photodetectors perform well in many particle and medical physics applications, especially where good efficiency, insensitivity to magnetic field and precise timing are required. In Cherenkov time-of-flight positron emission tomography the requirements for photodetector performance are especially high. On average only a couple of photons are available for detection and the best possible timing resolution is needed. Using SiPMs as photodetectors enables good detection efficiency, but the large sensitive area devices needed have somewhat limited time resolution for single photons. We have observed an additional degradation of the timing at very low light intensities due to delayed events in distribution of signals resulting from multiple fired micro cells. In this work we present the timing properties of AdvanSiD ASD-NUV3S-P-40 SiPM at single photon level picosecond laser illumination and a simple modification of the time-walk correction algorithm, that resulted in reduced degradation of timing resolution due to the delayed events.

Competency-based education in anesthesiology: history and challenges.

PubMed

Ebert, Thomas J; Fox, Chris A

2014-01-01

The Accreditation Council for Graduate Medical Education is transitioning to a competency-based system with milestones to measure progress and define success of residents. The confines of the time-based residency will be relaxed. Curriculum must be redesigned and assessments will need to be precise and in-depth. Core anesthesiology faculty will be identified and will be the "trained observers" of the residents' progress. There will be logistic challenges requiring creative management by program directors. There may be residents who achieve "expert" status earlier than the required 36 months of clinical anesthesia education, whereas others may struggle to achieve acceptable status and will require additional education time. Faculty must accept both extremes without judgment. Innovative new educational opportunities will need to be created for fast learners. Finally, it will be important that residents embrace this change. This will require programs to clearly define the specific aims and measurement endpoints for advancement and success.

Concurrent access to a virtual microscope using a web service oriented architecture

NASA Astrophysics Data System (ADS)

Corredor, Germán.; Iregui, Marcela; Arias, Viviana; Romero, Eduardo

2013-11-01

Virtual microscopy (VM) facilitates visualization and deployment of histopathological virtual slides (VS), a useful tool for education, research and diagnosis. In recent years, it has become popular, yet its use is still limited basically because of the very large sizes of VS, typically of the order of gigabytes. Such volume of data requires efficacious and efficient strategies to access the VS content. In an educative or research scenario, several users may require to access and interact with VS at the same time, so, due to large data size, a very expensive and powerful infrastructure is usually required. This article introduces a novel JPEG2000-based service oriented architecture for streaming and visualizing very large images under scalable strategies, which in addition need not require very specialized infrastructure. Results suggest that the proposed architecture enables transmission and simultaneous visualization of large images, while it is efficient using resources and offering users proper response times.

Lossless data compression for improving the performance of a GPU-based beamformer.

PubMed

Lok, U-Wai; Fan, Gang-Wei; Li, Pai-Chi

2015-04-01

The powerful parallel computation ability of a graphics processing unit (GPU) makes it feasible to perform dynamic receive beamforming However, a real time GPU-based beamformer requires high data rate to transfer radio-frequency (RF) data from hardware to software memory, as well as from central processing unit (CPU) to GPU memory. There are data compression methods (e.g. Joint Photographic Experts Group (JPEG)) available for the hardware front end to reduce data size, alleviating the data transfer requirement of the hardware interface. Nevertheless, the required decoding time may even be larger than the transmission time of its original data, in turn degrading the overall performance of the GPU-based beamformer. This article proposes and implements a lossless compression-decompression algorithm, which enables in parallel compression and decompression of data. By this means, the data transfer requirement of hardware interface and the transmission time of CPU to GPU data transfers are reduced, without sacrificing image quality. In simulation results, the compression ratio reached around 1.7. The encoder design of our lossless compression approach requires low hardware resources and reasonable latency in a field programmable gate array. In addition, the transmission time of transferring data from CPU to GPU with the parallel decoding process improved by threefold, as compared with transferring original uncompressed data. These results show that our proposed lossless compression plus parallel decoder approach not only mitigate the transmission bandwidth requirement to transfer data from hardware front end to software system but also reduce the transmission time for CPU to GPU data transfer. © The Author(s) 2014.

Development of microsatellite markers in Parthenium ssp.

USDA-ARS?s Scientific Manuscript database

Molecular markers provide the most efficient means to study genetic diversity within and among species of a particular genus. In addition, molecular markers can facilitate breeding efforts by providing tools necessary to reduce the time required to obtain recombinant genotypes with improved agricu...

USE OF TAQMAN TO ENUMERATE ENTEROCOCCUS FAECALIS IN WATER

EPA Science Inventory

The Polymerase Chain Reaction (PCR) has become a useful tool in the detection of microorganisms. However, conventional PCR is somewhat time-consuming considering that additional steps (e.g., gel electrophoresis and gene sequencing) are required to confirm the presence of the tar...

22 CFR 41.103 - Filing an application.

Code of Federal Regulations, 2010 CFR

2010-04-01

... to appear for a personal interview must provide a biometric, which will serve to authenticate... time of interview. The consular officer may require the submission of additional necessary information or question an alien on any relevant matter whenever the consular officer believes that the...

22 CFR 41.103 - Filing an application.

Code of Federal Regulations, 2011 CFR

2011-04-01

... to appear for a personal interview must provide a biometric, which will serve to authenticate... time of interview. The consular officer may require the submission of additional necessary information or question an alien on any relevant matter whenever the consular officer believes that the...

Examination of Calcium Silicate Cements with Low-Viscosity Methyl Cellulose or Hydroxypropyl Cellulose Additive.

PubMed

Baba, Toshiaki; Tsujimoto, Yasuhisa

2016-01-01

The purpose of this study was to improve the operability of calcium silicate cements (CSCs) such as mineral trioxide aggregate (MTA) cement. The flow, working time, and setting time of CSCs with different compositions containing low-viscosity methyl cellulose (MC) or hydroxypropyl cellulose (HPC) additive were examined according to ISO 6876-2012; calcium ion release analysis was also conducted. MTA and low-heat Portland cement (LPC) including 20% fine particle zirconium oxide (ZO group), LPC including zirconium oxide and 2 wt% low-viscosity MC (MC group), and HPC (HPC group) were tested. MC and HPC groups exhibited significantly higher flow values and setting times than other groups ( p < 0.05). Additionally, flow values of these groups were higher than the ISO 6876-2012 reference values; furthermore, working times were over 10 min. Calcium ion release was retarded with ZO, MC, and HPC groups compared with MTA. The concentration of calcium ions was decreased by the addition of the MC or HPC group compared with the ZO group. When low-viscosity MC or HPC was added, the composition of CSCs changed, thus fulfilling the requirements for use as root canal sealer. Calcium ion release by CSCs was affected by changing the CSC composition via the addition of MC or HPC.

Examination of Calcium Silicate Cements with Low-Viscosity Methyl Cellulose or Hydroxypropyl Cellulose Additive

PubMed Central

Tsujimoto, Yasuhisa

2016-01-01

The purpose of this study was to improve the operability of calcium silicate cements (CSCs) such as mineral trioxide aggregate (MTA) cement. The flow, working time, and setting time of CSCs with different compositions containing low-viscosity methyl cellulose (MC) or hydroxypropyl cellulose (HPC) additive were examined according to ISO 6876-2012; calcium ion release analysis was also conducted. MTA and low-heat Portland cement (LPC) including 20% fine particle zirconium oxide (ZO group), LPC including zirconium oxide and 2 wt% low-viscosity MC (MC group), and HPC (HPC group) were tested. MC and HPC groups exhibited significantly higher flow values and setting times than other groups (p < 0.05). Additionally, flow values of these groups were higher than the ISO 6876-2012 reference values; furthermore, working times were over 10 min. Calcium ion release was retarded with ZO, MC, and HPC groups compared with MTA. The concentration of calcium ions was decreased by the addition of the MC or HPC group compared with the ZO group. When low-viscosity MC or HPC was added, the composition of CSCs changed, thus fulfilling the requirements for use as root canal sealer. Calcium ion release by CSCs was affected by changing the CSC composition via the addition of MC or HPC. PMID:27981048

Clinical usefulness of augmented reality using infrared camera based real-time feedback on gait function in cerebral palsy: a case study.

PubMed

Lee, Byoung-Hee

2016-04-01

[Purpose] This study investigated the effects of real-time feedback using infrared camera recognition technology-based augmented reality in gait training for children with cerebral palsy. [Subjects] Two subjects with cerebral palsy were recruited. [Methods] In this study, augmented reality based real-time feedback training was conducted for the subjects in two 30-minute sessions per week for four weeks. Spatiotemporal gait parameters were used to measure the effect of augmented reality-based real-time feedback training. [Results] Velocity, cadence, bilateral step and stride length, and functional ambulation improved after the intervention in both cases. [Conclusion] Although additional follow-up studies of the augmented reality based real-time feedback training are required, the results of this study demonstrate that it improved the gait ability of two children with cerebral palsy. These findings suggest a variety of applications of conservative therapeutic methods which require future clinical trials.

Laser Synthesis of Supported Catalysts for Carbon Nanotubes

NASA Technical Reports Server (NTRS)

VanderWal, Randall L.; Ticich, Thomas M.; Sherry, Leif J.; Hall, Lee J.; Schubert, Kathy (Technical Monitor)

2003-01-01

Four methods of laser assisted catalyst generation for carbon nanotube (CNT) synthesis have been tested. These include pulsed laser transfer (PLT), photolytic deposition (PLD), photothermal deposition (PTD) and laser ablation deposition (LABD). Results from each method are compared based on CNT yield, morphology and structure. Under the conditions tested, the PLT was the easiest method to implement, required the least time and also yielded the best pattemation. The photolytic and photothermal methods required organometallics, extended processing time and partial vacuums. The latter two requirements also held for the ablation deposition approach. In addition to control of the substrate position, controlled deposition duration was necessary to achieve an active catalyst layer. Although all methods were tested on both metal and quartz substrates, only the quartz substrates proved to be inactive towards the deposited catalyst particles.

Structures and materials technology issues for reusable launch vehicles

NASA Technical Reports Server (NTRS)

Dixon, S. C.; Tenney, D. R.; Rummler, D. R.; Wieting, A. R.; Bader, R. M.

1985-01-01

Projected space missions for both civil and defense needs require significant improvements in structures and materials technology for reusable launch vehicles: reductions in structural weight compared to the Space Shuttle Orbiter of up to 25% or more, a possible factor of 5 or more increase in mission life, increases in maximum use temperature of the external surface, reusable containment of cryogenic hydrogen and oxygen, significant reductions in operational costs, and possibly less lead time between technology readiness and initial operational capability. In addition, there is increasing interest in hypersonic airbreathing propulsion for launch and transmospheric vehicles, and such systems require regeneratively cooled structure. The technology issues are addressed, giving brief assessments of the state-of-the-art and proposed activities to meet the technology requirements in a timely manner.

A Systematic Method for Verification and Validation of Gyrokinetic Microstability Codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bravenec, Ronald

My original proposal for the period Feb. 15, 2014 through Feb. 14, 2017 called for an integrated validation and verification effort carried out by myself with collaborators. The validation component would require experimental profile and power-balance analysis. In addition, it would require running the gyrokinetic codes varying the input profiles within experimental uncertainties to seek agreement with experiment before discounting a code as invalidated. Therefore, validation would require a major increase of effort over my previous grant periods which covered only code verification (code benchmarking). Consequently, I had requested full-time funding. Instead, I am being funded at somewhat less thanmore » half time (5 calendar months per year). As a consequence, I decided to forego the validation component and to only continue the verification efforts.« less

Transfers between libration-point orbits in the elliptic restricted problem

NASA Astrophysics Data System (ADS)

Hiday, L. A.; Howell, K. C.

The present time-fixed impulsive transfers between 3D libration point orbits in the vicinity of the interior L(1) libration point of the sun-earth-moon barycenter system are 'optimal' in that the total characteristic velocity required for implementation of the transfer exhibits a local minimum. The conditions necessary for a time-fixed, two-impulse transfer trajectory to be optimal are stated in terms of the primer vector, and the conditions necessary for satisfying the local optimality of a transfer trajectory containing additional impulses are addressed by requiring continuity of the Hamiltonian and the derivative of the primer vector at all interior impulses.

Widefield Two-Photon Excitation without Scanning: Live Cell Microscopy with High Time Resolution and Low Photo-Bleaching

PubMed Central

Amor, Rumelo; McDonald, Alison; Trägårdh, Johanna; Robb, Gillian; Wilson, Louise; Abdul Rahman, Nor Zaihana; Dempster, John; Amos, William Bradshaw; Bushell, Trevor J.; McConnell, Gail

2016-01-01

We demonstrate fluorescence imaging by two-photon excitation without scanning in biological specimens as previously described by Hwang and co-workers, but with an increased field size and with framing rates of up to 100 Hz. During recordings of synaptically-driven Ca2+ events in primary rat hippocampal neurone cultures loaded with the fluorescent Ca2+ indicator Fluo-4 AM, we have observed greatly reduced photo-bleaching in comparison with single-photon excitation. This method, which requires no costly additions to the microscope, promises to be useful for work where high time-resolution is required. PMID:26824845

The workload analysis in welding workshop

NASA Astrophysics Data System (ADS)

Wahyuni, D.; Budiman, I.; Tryana Sembiring, M.; Sitorus, E.; Nasution, H.

2018-03-01

This research was conducted in welding workshop which produces doors, fences, canopies, etc., according to customer’s order. The symptoms of excessive workload were seen from the fact of employees complaint, requisition for additional employees, the lateness of completion time (there were 11 times of lateness from 28 orders, and 7 customers gave complaints). The top management of the workshop assumes that employees’ workload was still a tolerable limit. Therefore, it was required workload analysis to determine the number of employees required. The Workload was measured by using a physiological method and workload analysis. The result of this research can be utilized by the workshop for a better workload management.

Zone plate method for electronic holographic display using resolution redistribution technique.

PubMed

Takaki, Yasuhiro; Nakamura, Junya

2011-07-18

The resolution redistribution (RR) technique can increase the horizontal viewing-zone angle and screen size of electronic holographic display. The present study developed a zone plate method that would reduce hologram calculation time for the RR technique. This method enables calculation of an image displayed on a spatial light modulator by performing additions of the zone plates, while the previous calculation method required performing the Fourier transform twice. The derivation and modeling of the zone plate are shown. In addition, the look-up table approach was introduced for further reduction in computation time. Experimental verification using a holographic display module based on the RR technique is presented.

Nursing home medication administration cost minimization analysis.

PubMed

Hamrick, Irene; Nye, Ann Marie; Gardner, Casey K

2007-03-01

To assess the time it takes nurses to administer medications in the nursing home setting, to calculate nursing cost of medication administration, and to determine whether using extended-release products are justified by decreasing nursing costs. Cost-minimization analysis using observational data from a time-motion analysis. Two 150-bed nursing homes in rural eastern North Carolina. Nurses working during first and second shifts. Nurses were timed as they each administered medications to 12 patients. The mean time required to administer each dosage form was calculated. The cost of nursing time was based on the average nursing staff salary of $20.45 per hour as reported by the directors of nursing. Time and cost to dispense one more medication during an existing medication pass and an additional medication pass are calculated. The time to administer an additional dose of an oral medication to one patient was 45.01 seconds during an already scheduled medication pass and 63.05 seconds during a new medication pass. The cost of adding an oral medication once a day for a patient will cost $7.67 per month if administered at the same time as other medications or $10.74 per month if a new medication pass is required. The administration of other dosage forms, such as crushed, percutaneous enteroscopic gastrostomy, injection, and patch was more time involved and, thus, costlier. Formulas are provided to calculate medication administration cost based on local salary. Nursing time and costs for medication administration in the nursing home are great and should be considered when selecting a product. This may justify the selection of higher cost extended-release products.

2013 mask industry survey

NASA Astrophysics Data System (ADS)

Malloy, Matt

2013-09-01

A comprehensive survey was sent to merchant and captive mask shops to gather information about the mask industry as an objective assessment of its overall condition. 2013 marks the 12th consecutive year for this process. Historical topics including general mask profile, mask processing, data and write time, yield and yield loss, delivery times, maintenance, and returns were included and new topics were added. Within each category are multiple questions that result in a detailed profile of both the business and technical status of the mask industry. While each year's survey includes minor updates based on feedback from past years and the need to collect additional data on key topics, the bulk of the survey and reporting structure have remained relatively constant. A series of improvements is being phased in beginning in 2013 to add value to a wider audience, while at the same time retaining the historical content required for trend analyses of the traditional metrics. Additions in 2013 include topics such as top challenges, future concerns, and additional details in key aspects of mask masking, such as the number of masks per mask set per ground rule, minimum mask resolution shipped, and yield by ground rule. These expansions beyond the historical topics are aimed at identifying common issues, gaps, and needs. They will also provide a better understanding of real-life mask requirements and capabilities for comparison to the International Technology Roadmap for Semiconductors (ITRS).

Additive Manufacturing of Tooling for Refrigeration Cabinet Foaming Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Post, Brian K; Nuttall, David; Cukier, Michael

The primary objective of this project was to leverage the Big Area Additive Manufacturing (BAAM) process and materials into a long term, quick change tooling concept to drastically reduce product lead and development timelines and costs. Current refrigeration foam molds are complicated to manufacture involving casting several aluminum parts in an approximate shape, machining components of the molds and post fitting and shimming of the parts in an articulated fixture. The total process timeline can take over 6 months. The foaming process is slower than required for production, therefore multiple fixtures, 10 to 27, are required per refrigerator model. Moldsmore » are particular to a specific product configuration making mixed model assembly challenging for sequencing, mold changes or auto changeover features. The initial goal was to create a tool leveraging the ORNL materials and additive process to build a tool in 4 to 6 weeks or less. A secondary goal was to create common fixture cores and provide lightweight fixture sections that could be revised in a very short time to increase equipment flexibility reduce lead times, lower the barriers to first production trials, and reduce tooling costs.« less

Assessing direct analysis in real-time-mass spectrometry (DART-MS) for the rapid identification of additives in food packaging.

PubMed

Ackerman, L K; Noonan, G O; Begley, T H

2009-12-01

The ambient ionization technique direct analysis in real time (DART) was characterized and evaluated for the screening of food packaging for the presence of packaging additives using a benchtop mass spectrometer (MS). Approximate optimum conditions were determined for 13 common food-packaging additives, including plasticizers, anti-oxidants, colorants, grease-proofers, and ultraviolet light stabilizers. Method sensitivity and linearity were evaluated using solutions and characterized polymer samples. Additionally, the response of a model additive (di-ethyl-hexyl-phthalate) was examined across a range of sample positions, DART, and MS conditions (temperature, voltage and helium flow). Under optimal conditions, molecular ion (M+H+) was the major ion for most additives. Additive responses were highly sensitive to sample and DART source orientation, as well as to DART flow rates, temperatures, and MS inlet voltages, respectively. DART-MS response was neither consistently linear nor quantitative in this setting, and sensitivity varied by additive. All additives studied were rapidly identified in multiple food-packaging materials by DART-MS/MS, suggesting this technique can be used to screen food packaging rapidly. However, method sensitivity and quantitation requires further study and improvement.

Comparison between open and laparoscopic repair of perforated peptic ulcer disease.

PubMed

Bhogal, Ricky H; Athwal, Ruvinder; Durkin, Damien; Deakin, Mark; Cheruvu, Chandra N V

2008-11-01

The place of laparoscopic repair of perforated peptic ulcer followed by peritoneal toilet has been established, although it is not routinely practiced. This prospective study compared laparoscopic and open repair of perforated peptic ulcer disease. We evaluated whether the early results from laparoscopic repair resulted in improved patient outcome compared with conventional open repair. All patients who underwent repair of perforated peptic ulcer disease during a 12-month period in our unit were included in the study. The primary end points that were evaluated were total operative time, nasogastric tube utilisation, intravenous fluid requirement, total time of urinary catheter and abdominal drainage usage, time taken to return to normal diet, intravenous/intramuscular opiate use, time to full mobilization, and total in-patient hospital stay. Thirty-three patients underwent surgical repair of perforated peptic ulcer disease (19 laparoscopic repairs and 14 open repairs; mean age, 54.2 (range, 32-82) years). There was no increase in total operative time in patients who had undergone laparoscopic repair (mean: 61 minutes laparoscopic versus 57 minutes open). There was significantly less requirement for intravenous/intramuscular opiate analgesia in patients who had undergone laparoscopic repair (mean time to oral analgesia: 1.2 days laparoscopic versus 3.8 days open). In addition there was a significant decrease in the time that the nasogastric tube (mean: 2.1 days laparoscopic versus 3.1 days open), urinary catheter (mean: 2.3 days laparoscopic versus 3.7 days open) and abdominal drain (mean: 2.2 days laparoscopic versus 3.8 days open) were required during the postoperative period. Patients who had undergone laparoscopic repair required less intravenous fluids (mean: 1.4 days laparoscopic versus 3.1 days open) and returned to normal diet (mean: 2.3 days laparoscopic versus 4.8 days open) and full mobilization significantly earlier than those who had undergone open repair (mean: 2.3 days laparoscopic versus 3.3 days open). In addition, patients who had undergone laparoscopic repair required a shorter in-patient hospital stay (mean: 3.1 days laparoscopic versus 4.3 days open). Laparoscopic repair is a viable and safe surgical option for patients with perforated peptic ulcer disease and should be considered for all patients, providing that the necessary expertise is available.

A Simple and Inexpensive Device for Slow, Controlled Addition of a Solution to a Reaction Mixture

NASA Astrophysics Data System (ADS)

Osvath, Peter

1995-07-01

A number of reactions require the slow and controlled addition of a solution containing one reagent to another. Attempting to control the flow rate over a number of hours using a conventional constant pressure addition funnel is a frustrating exercise; commercially available constant volume addition funnels are expensive and must be adjusted by trial and error each time a reaction is carried out. The use of an (expensive) peristaltic pump or syringe pump overcomes these problems but can introduce other complications. We have recently had occasion to carry out the synthesis of thioether macrocycles and cages requiring the slow and controlled addition of DMF solutions of (offensively odoriferous) thiols or (air-sensitive) thiolates to a reactant solution under nitrogen(1), Although the use of a syringe pump was called for, there are obvious difficulties associated with purging the solution and assembling such an apparatus under nitrogen, and we report a simple and inexpensive solution. A Male Luer Lock tip (recovered from a broken syringe) was sweated onto the flattened tip of a pressure-equalizing addition funnel and a syringe needle was attached. Judicious selection of needle length, bore size, and reactant volume can be used to control the addition time simply and reproducibly. With a 250-mL funnel, the flow rate changes by <25% from the beginning to the end of the addition. (In fact, a reduction in the rate of addition may even be advantageous as the reaction proceeds, the reagent in the receiving flask is consumed, its concentration drops, and the rate of reaction will decrease). A piece of fine Teflon tubing of appropriate length attached to the needle can be used to reduce the flow rate even further, but this is only necessary for very slow rates of addition. For example, the time of addition of 200 mL, of an ethanolic solution could be varied from approximately 5 minutes (150mm/17 gauge) to approximately 5 h (200mm/22 gauge), and once the addition time for a particular needle length/bore is determined, the tap on the addition funnel is turned fully on, so no adjustment is necessary. When needles with a particularly fine bore are used, a small plug of glass wool should be inserted in the constriction above the tap, to filter the solution and prevent blockage of the needle. An inert atmosphere is readily maintained throughout the system. The elimination of atmospheric contamination, containment of odors and controlled slow addition have led to improved yields and less complaints from fellow inhabitants of the laboratory! Literature Cited 1. Osvath, P.; Sargeson, A. M.; Skelton, B. W.; White, A. H. J. Chem. Soc., Chem. Commun. 1991, 1036. Osvath. P.; Sargeson, A. J. Chem. Soc., Chem. Commun. 1993, 40.

A controlled investigation of propofol, thiopentone and methohexitone.

PubMed

Gold, M I; Abraham, E C; Herrington, C

1987-09-01

This was a randomized study of 180 ASA physical status I and II patients, 60 in each group who received propofol (PROP), 2.5 mg . kg-1, thiopentone (THIO), 4 mg . kg-1, or methohexitone (METH), 1.5 mg . kg-1. Control values, followed by changes after induction and during a 3-min delay before intubation were recorded for the following parameters: heart rate (HR), systolic and diastolic blood pressures (SBP, DBP), respiratory rate (RR), end-tidal CO2 (PETCO2), and induction time (IT). In addition, the incidence of adverse reactions and time for recovery from anaesthesia were noted. The IT (mean +/- SE) was 35 +/- 1 sec for propofol, 35 +/- 1.2 sec for thiopentone and 34 +/- 1.4 sec for methohexitone. Ninety-three per cent of the PROP group fell asleep with one dose and required no additional doses. Fifty per cent of each of the THIO and METH groups required additional agents (p less than 0.05). METH was associated with the highest elevation in HR, PROP the least (p less than 0.05). PROP was associated with the most decrease in SBP and DBP and in addition respiratory depression (p less than 0.05). The incidence of injection pain or excitatory activity was equal in the three groups with the exception that 14 patients who received METH developed hiccoughs while none did in the other groups. PROP was associated with the most rapid recovery, particularly with respect to the orientation time. We conclude that PROP is an effective alternative to barbiturate induction and that the published recommended doses of THIO and METH are often ineffective.

Patient expectations and costs of immediate reporting of screening mammography: talk isn't cheap.

PubMed

Raza, S; Rosen, M P; Chorny, K; Mehta, T S; Hulka, C A; Baum, J K

2001-09-01

Our purpose was to determine whether patients prefer immediate or delayed results of screening mammography and to determine the cost of immediate reporting at our institution. A survey was anonymously and randomly distributed to 129 women who were 35-70 years old during a visit to their primary care physician, asking the women's preference for receiving mammography results by one of two systems: by letter with a return visit for any additional tests; or by speaking at once with the radiologist, with the option of additional tests being performed during the same visit. Patients' willingness to pay for the latter service was also determined. A cost identification model was constructed using commercially available software. We considered the impact on radiologists' and technologists' time and the need for additional equipment and space, and we analyzed the effect on the cost of immediate reporting. One hundred twenty (93%) surveys were completed. Eighty women (67%) preferred immediate reporting, and 62 (78%) of these 80 patients would wait 30-60 min. The additional cost of immediate reporting is $28.22 per patient. Only 11% of patients were willing to pay this additional cost. When new equipment and space were not required, the cost would increase by $4.38. This cost was most influenced by the time required to give patients normal results. Most surveyed patients preferred speaking with a radiologist immediately but were unwilling to pay additional fees. Radiologists, hospital administrators, and health care planners must be aware of the costs of immediate reporting and must factor these costs into any change in hospital or national policy.

Impact of Interlayer Dwell Time on Microstructure and Mechanical Properties of Nickel and Titanium Alloys

NASA Astrophysics Data System (ADS)

Foster, B. K.; Beese, A. M.; Keist, J. S.; McHale, E. T.; Palmer, T. A.

2017-09-01

Path planning in additive manufacturing (AM) processes has an impact on the thermal histories experienced at discrete locations in simple and complex AM structures. One component of path planning in directed energy deposition is the time required for the laser or heat source to return to a given location to add another layer of material. As structures become larger and more complex, the length of this interlayer dwell time can significantly impact the resulting thermal histories. The impact of varying dwell times between 0 and 40 seconds on the microstructural and mechanical properties of Inconel® 625 and Ti-6Al-4V builds has been characterized. Even though these materials display different microstructures and solid-state phase transformations, the addition of an interlayer dwell generally led to a finer microstructure in both materials that impacted the resulting mechanical properties. With the addition of interlayer dwell times up to 40 seconds in the Inconel® 625 builds, finer secondary dendrite arm spacing values, produced by changes in the thermal history, correspond to increased yield and tensile strengths. These mechanical properties did not appear to change significantly, however, for dwell times greater than 20 seconds in the Inconel® 625 builds, indicating that longer dwell times have a minimal impact. The addition of interlayer dwell times in Ti-6Al-4V builds resulted in a slight decrease in the measured alpha lath widths and a much more noticeable decrease in the width of prior beta grains. In addition, the yield and tensile values continued to increase, nearly reaching the values observed in the rolled plate substrate material with dwell times up to 40 seconds.

10 CFR 431.17 - Determination of efficiency.

Code of Federal Regulations, 2011 CFR

2011-01-01

... different horsepowers without duplication; (C) The basic models should be of different frame number series... be produced over a reasonable period of time (approximately 180 days), then each unit shall be tested... design may be substituted without requiring additional testing if the represented measures of energy...

Precision agriculture in large-scale mechanized farming

USDA-ARS?s Scientific Manuscript database

Precision agriculture involves a great deal of technologies and requires additional investments of money and time, but it can be practiced at different levels depending on the specific field and crop conditions and the resources and technology services available to the farmer. If practiced properly,...

All-season flash flood forecasting system for real-time operations

USDA-ARS?s Scientific Manuscript database

Flash floods can cause extensive damage to both life and property, especially because they are difficult to predict. Flash flood prediction requires high-resolution meteorologic observations and predictions, as well as calibrated hydrologic models in addition to extensive data handling. We have de...

SO2 SCRUBBING TECHNOLOGIES: A REVIEW

EPA Science Inventory

Electricity generating units may use sulfur dioxide (SO2) scrubbers to meet the requirements of Phase II of the Acid Rain S02 Reduction Program. Additionally, the use of scrubbers can result in reduction of mercury emissions. It is timely, therefore, to review the commercially av...

Revolution in Military Manpower: The Citizen-Warrior Total Career Continuum Construct

DTIC Science & Technology

2014-02-13

stressed career-fields, professional military education, and other situations to provide additional 12 incentives for desired behaviors and force...authorized telecommuting workload. 33 An example of an accrued service obligation would be required active service for a specified period of time after

48 CFR 7.107 - Additional requirements for acquisitions involving bundling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the Government. However, because of the potential impact on small business participation, the head of... performance or efficiency, reduction in acquisition cycle times, better terms and conditions, and any other...; and (2) The acquisition strategy provides for maximum practicable participation by small business...

Compatibility of aggregate, asphalt cement and antistrip materials : final report.

DOT National Transportation Integrated Search

1995-12-01

Studies undertaken for the FHWA revealed a significant moisture damage problem in Louisiana hot mix pavements. At that time an antistrip additive from a qualified products list was required at the set rate of 0.5 percent weight of asphalt cement. The...

On-patient see-through augmented reality based on visual SLAM.

PubMed

Mahmoud, Nader; Grasa, Óscar G; Nicolau, Stéphane A; Doignon, Christophe; Soler, Luc; Marescaux, Jacques; Montiel, J M M

2017-01-01

An augmented reality system to visualize a 3D preoperative anatomical model on intra-operative patient is proposed. The hardware requirement is commercial tablet-PC equipped with a camera. Thus, no external tracking device nor artificial landmarks on the patient are required. We resort to visual SLAM to provide markerless real-time tablet-PC camera location with respect to the patient. The preoperative model is registered with respect to the patient through 4-6 anchor points. The anchors correspond to anatomical references selected on the tablet-PC screen at the beginning of the procedure. Accurate and real-time preoperative model alignment (approximately 5-mm mean FRE and TRE) was achieved, even when anchors were not visible in the current field of view. The system has been experimentally validated on human volunteers, in vivo pigs and a phantom. The proposed system can be smoothly integrated into the surgical workflow because it: (1) operates in real time, (2) requires minimal additional hardware only a tablet-PC with camera, (3) is robust to occlusion, (4) requires minimal interaction from the medical staff.

"Boldness be my friend" (Shakespeare; Cymbeline).

PubMed

Altman, Jessica K; Tallman, Martin S

2011-12-15

Au et al report in this issue of Blood that oral arsenic trioxide (ATO) may be safely used in maintenance therapy in acute promyelocytic leukemia (APL). This is a major improvement in convenience given that intravenous (IV)ATO requires daily administration for weeks at a time. In addition, the oral formulation may be less toxic. The time seems right to carefully explore the introduction of oral ATO earlier in treatment of the disease.

Required and Elective Experiences During the 4th Year: An Analysis of ACGME Accredited Psychiatry Residency Program Websites.

PubMed

Vestal, Heather S; Belitsky, Richard; Bernstein, Carol A; Chaukos, Deanna; Cohen, Mitchell B; Dickstein, Leah J; Hilty, Donald M; Hutner, Lucy; Sakman, Ferda; Scheiber, Stephen C; Wrzosek, Marika I; Silberman, Edward K

2016-10-01

The objective of this study was to assess and describe required and elective components of the 4th post-graduate year (PGY4) in psychiatry residency programs. We reviewed the websites of all 193 2014-2015 ACGME accredited psychiatry residency programs for content describing the specific components of the PGY4 year. Nearly all residency programs (99 %) had some form of required experiences during the PGY4 year. Ninety-four percent had clinical requirements for PGY4 residents, with longitudinal outpatient clinic being the most common (77 %). All programs offered some elective time during PGY4, but the amount of time ranged from 2 months to 100 %. Virtually all residency programs include some requirements in the 4th year (most commonly didactics and outpatient clinic) in addition to a broad array of elective experiences. Although 3 years may suffice for residents to complete ACGME requirements, a variety of factors may motivate programs to include required 4th year curricula. Future studies should explore the rationales for and possible benefits of programmatic requirements throughout 4 versus only 3 years of psychiatric training.

Combined effects of night warming and light pollution on predator-prey interactions.

PubMed

Miller, Colleen R; Barton, Brandon T; Zhu, Likai; Radeloff, Volker C; Oliver, Kerry M; Harmon, Jason P; Ives, Anthony R

2017-10-11

Interactions between multiple anthropogenic environmental changes can drive non-additive effects in ecological systems, and the non-additive effects can in turn be amplified or dampened by spatial covariation among environmental changes. We investigated the combined effects of night-time warming and light pollution on pea aphids and two predatory ladybeetle species. As expected, neither night-time warming nor light pollution changed the suppression of aphids by the ladybeetle species that forages effectively in darkness. However, for the more-visual predator, warming and light had non-additive effects in which together they caused much lower aphid abundances. These results are particularly relevant for agriculture near urban areas that experience both light pollution and warming from urban heat islands. Because warming and light pollution can have non-additive effects, predicting their possible combined consequences over broad spatial scales requires knowing how they co-occur. We found that night-time temperature change since 1949 covaried positively with light pollution, which has the potential to increase their non-additive effects on pea aphid control by 70% in US alfalfa. Our results highlight the importance of non-additive effects of multiple environmental factors on species and food webs, especially when these factors co-occur. © 2017 The Author(s).

Timing of decontamination and treatment in case of percutaneous VX poisoning: a mini review.

PubMed

Joosen, Marloes J A; van der Schans, Marcel J; Kuijpers, Willem C; van Helden, Herman P M; Noort, Daan

2013-03-25

Low volatile organophosphorous nerve agents such as VX, will most likely enter the body via the skin. The pharmacokinetics of drugs such as oximes, atropine and diazepam, are not aligned with the variable and persistent toxicokinetics of the agent. Repeated administration of these drugs showed to improve treatment efficacy compared to a single injection treatment. Because of the effectiveness of continuous treatment, it was investigated to what extent a subchronic pretreatment with carbamate (pyridostigmine or physostigmine combined with either procyclidine or scopolamine) would protect against percutaneous VX exposure. Inclusion of scopolamine in the pretreatment prevented seizures in all animals, but none of the pretreatments affected survival time or the onset time of cholinergic signs. These results indicate that percutaneous poisoning with VX requires additional conventional treatment in addition to the current pretreatment regimen. Decontamination of VX-exposed skin is one of the most important countermeasures to mitigate the effects of the exposure. To evaluate the window of opportunity for decontamination, the fielded skin decontaminant Reactive Skin Decontaminant Lotion (RSDL) was tested at different times in hairless guinea pigs percutaneously challenged with 4× LD50 VX in IPA. The results showed that RSDL decontamination at 15 min after exposure could not prevent progressive blood cholinesterase inhibition and therefore would still require additional treatment. A similar decontamination regimen with RSDL at 90 min showed that it still might effectively increase the time window of opportunity for treatment. In conclusion, the delay in absorption presents a window of opportunity for decontamination and treatment. The continuous release of VX from the skin presents a significant challenge for efficacious therapy, which should ideally consist of thorough decontamination and continuous treatment. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

The ALMA Band 3 (84-116 GHz) receiver production plan

NASA Astrophysics Data System (ADS)

Yeung, Keith; Claude, Stéphane; Loop, David

2008-07-01

The NRC Herzberg Institute of Astrophysics (NRC-HIA) is currently responsible to contribute Band 3 (84-116 GHz) receivers to the international ALMA project - a partnership involving North America, Europe and, now, Asia. Not only are the technical requirements for these receivers far more stringent than those for any existing radio astronomy receivers operating at these frequencies, but the delivery schedule for these receivers is equally challenging. Since the Asian partnership joined the ALMA project in 2006, NRC-HIA has been asked to deliver an additional 11 cartridges, for a total of 73 units. Some of these new cartridges will be used for the ALMA Compact Array (ACA) and others as spares. Moreover, the project has also requested that these additional cartridges be delivered in the same time period as the original 62 units. To meet this requirement, production must increase from the existing rate of one unit every four weeks to one every two, taxing the existing production infrastructure at NRC-HIA. Additional test facilities and human resources must be planned to sustain the required production rate over the next several years. Industrial involvement is one of the important elements in our production plan. In order to supplement the existing human resources at NRC-HIA, we are planning to outsource a number of low-risk and labor-intensive tasks to industry. However, NRC-HIA will retain overall project management responsibility and will conduct all the cartridge integration and acceptance test activities in-house. This paper focuses on the resource estimation, planning and project management required to deliver the Band 3 receivers to the ALMA project on time and on budget.

Empirical Analysis of the Variability of Wind Generation in India: Implications for Grid Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phadke, Amol; Abhyankar, NIkit; Rao, Poorvi

We analyze variability in load and wind generation in India to assess its implications for grid integration of large scale wind projects using actual wind generation and load data from two states in India, Karnataka and Tamil Nadu. We compare the largest variations in load and net load (load ?wind, i.e., load after integrating wind) that the generation fleet has to meet. In Tamil Nadu, where wind capacity is about 53percent of the peak demand, we find that the additional variation added due to wind over the current variation in load is modest; if wind penetration reaches 15percent and 30percentmore » by energy, the additional hourly variation is less than 0.5percent and 4.5percent of the peak demand respectively for 99percent of the time. For wind penetration of 15percent by energy, Tamil Nadu system is found to be capable of meeting the additional ramping requirement for 98.8percent of the time. Potential higher uncertainty in net load compared to load is found to have limited impact on ramping capability requirements of the system if coal plants can me ramped down to 50percent of their capacity. Load and wind aggregation in Tamil Nadu and Karnataka is found to lower the variation by at least 20percent indicating the benefits geographic diversification. These findings suggest modest additional flexible capacity requirements and costs for absorbing variation in wind power and indicate that the potential capacity support (if wind does not generate enough during peak periods) may be the issue that has more bearing on the economics of integrating wind« less

Development of small scale cluster computer for numerical analysis

NASA Astrophysics Data System (ADS)

Zulkifli, N. H. N.; Sapit, A.; Mohammed, A. N.

2017-09-01

In this study, two units of personal computer were successfully networked together to form a small scale cluster. Each of the processor involved are multicore processor which has four cores in it, thus made this cluster to have eight processors. Here, the cluster incorporate Ubuntu 14.04 LINUX environment with MPI implementation (MPICH2). Two main tests were conducted in order to test the cluster, which is communication test and performance test. The communication test was done to make sure that the computers are able to pass the required information without any problem and were done by using simple MPI Hello Program where the program written in C language. Additional, performance test was also done to prove that this cluster calculation performance is much better than single CPU computer. In this performance test, four tests were done by running the same code by using single node, 2 processors, 4 processors, and 8 processors. The result shows that with additional processors, the time required to solve the problem decrease. Time required for the calculation shorten to half when we double the processors. To conclude, we successfully develop a small scale cluster computer using common hardware which capable of higher computing power when compare to single CPU processor, and this can be beneficial for research that require high computing power especially numerical analysis such as finite element analysis, computational fluid dynamics, and computational physics analysis.

Costs of measuring leaf area index of corn

NASA Technical Reports Server (NTRS)

Daughtry, C. S. T.; Hollinger, S. E.

1984-01-01

The magnitude of plant-to-plant variability of leaf area of corn plants selected from uniform plots was examined and four representative methods for measuring leaf area index (LAI) were evaluated. The number of plants required and the relative costs for each sampling method were calculated to detect 10, 20, and 50% differences in LAI using 0.05 and 0.01 tests of significance and a 90% probability of success (beta = 0.1). The natural variability of leaf area per corn plant was nearly 10%. Additional variability or experimental error may be introduced by the measurement technique employed and by nonuniformity within the plot. Direct measurement of leaf area with an electronic area meter had the lowest CV, required that the fewest plants be sampled, but required approximately the same amount of time as the leaf area/weight ratio method to detect comparable differences. Indirect methods based on measurements of length and width of leaves required more plants but less total time than the direct method. Unless the coefficients for converting length and width to area are verified frequently, the indirect methods may be biased. When true differences in LAI among treatments exceed 50% of mean, all four methods are equal. The method of choice depends on the resources available, the differences to be detected, and what additional information, such as leaf weight or stalk weight, is also desired.

Floor Covering and Surface Identification for Assistive Mobile Robotic Real-Time Room Localization Application

PubMed Central

Gillham, Michael; Howells, Gareth; Spurgeon, Sarah; McElroy, Ben

2013-01-01

Assistive robotic applications require systems capable of interaction in the human world, a workspace which is highly dynamic and not always predictable. Mobile assistive devices face the additional and complex problem of when and if intervention should occur; therefore before any trajectory assistance is given, the robotic device must know where it is in real-time, without unnecessary disruption or delay to the user requirements. In this paper, we demonstrate a novel robust method for determining room identification from floor features in a real-time computational frame for autonomous and assistive robotics in the human environment. We utilize two inexpensive sensors: an optical mouse sensor for straightforward and rapid, texture or pattern sampling, and a four color photodiode light sensor for fast color determination. We show how data relating floor texture and color obtained from typical dynamic human environments, using these two sensors, compares favorably with data obtained from a standard webcam. We show that suitable data can be extracted from these two sensors at a rate 16 times faster than a standard webcam, and that these data are in a form which can be rapidly processed using readily available classification techniques, suitable for real-time system application. We achieved a 95% correct classification accuracy identifying 133 rooms' flooring from 35 classes, suitable for fast coarse global room localization application, boundary crossing detection, and additionally some degree of surface type identification. PMID:24351647

Floor covering and surface identification for assistive mobile robotic real-time room localization application.

PubMed

Gillham, Michael; Howells, Gareth; Spurgeon, Sarah; McElroy, Ben

2013-12-17

Assistive robotic applications require systems capable of interaction in the human world, a workspace which is highly dynamic and not always predictable. Mobile assistive devices face the additional and complex problem of when and if intervention should occur; therefore before any trajectory assistance is given, the robotic device must know where it is in real-time, without unnecessary disruption or delay to the user requirements. In this paper, we demonstrate a novel robust method for determining room identification from floor features in a real-time computational frame for autonomous and assistive robotics in the human environment. We utilize two inexpensive sensors: an optical mouse sensor for straightforward and rapid, texture or pattern sampling, and a four color photodiode light sensor for fast color determination. We show how data relating floor texture and color obtained from typical dynamic human environments, using these two sensors, compares favorably with data obtained from a standard webcam. We show that suitable data can be extracted from these two sensors at a rate 16 times faster than a standard webcam, and that these data are in a form which can be rapidly processed using readily available classification techniques, suitable for real-time system application. We achieved a 95% correct classification accuracy identifying 133 rooms' flooring from 35 classes, suitable for fast coarse global room localization application, boundary crossing detection, and additionally some degree of surface type identification.

ZERODUR thermo-mechanical modelling and advanced dilatometry for the ELT generation

NASA Astrophysics Data System (ADS)

Jedamzik, Ralf; Kunisch, Clemens; Westerhoff, Thomas

2016-07-01

Large amounts of low thermal expansion material are required for the upcoming ELT projects. The main mirror is designed using several hundreds of hexagonal 1.4 m sized mirror blanks. The M2 and M3 are monolithic 4 m class mirror blanks. The mirror blank material needs to fulfill tight requirements regarding CTE specification and homogeneity. Additionally the mirror blanks need to be dimensionally stable for more than 30 years. In particular, stress effects due to the changes in the environment shall not entail shape variation of more than 0.5 μm PV within 30 years. In 2010 SCHOTT developed a physically based model to describe the thermal and mechanical long time behavior of ZERODUR. The model enables simulation of the long time behavior of ZERODUR mirror blanks under realistic mechanical and thermal constraints. This presentation shows FEM simulation results on the long time behavior of the ELT M1, M2 and M3 mirror blanks under different loading conditions. Additionally the model results will be compared to an already 15 years lasting long time measurement of a ZERODUR sample at the German federal physical standardization institute (PTB). In recent years SCHOTT pushed the push rod dilatometer measurement technology to its limit. With the new Advanced Dilatometer CTE measurement accuracies of +- 3 ppb/K and reproducibilities of better 1 ppb/K have been achieved. The new Advanced Dilatometer exhibits excellent long time stability.

Benefits of xiphoidectomy in total gastrectomy: Technical note

PubMed Central

Mihmanlı, Mehmet; Köksal, Hakan Mustafa; Demir, Uygar; Işıl, Rıza Gürhan

2016-01-01

Objective: The esophago-gastric junction may be challenging during total gastrectomy due to gastric cancer. This situation may compromise the security of both the dissection and anastomosis. The purpose of this study was to investigate the usefulness of xiphoidectomy to overcome this issue. Material and Methods: The files of patients who underwent total gastrectomy + D2 lymph node dissection due to proximal gastric cancer or cardia cancer between April 2002–December 2013 were retrospectively evaluated. We assessed the outcome in patients with xiphoidectomy in addition to the midline incision in terms of xiphoidectomy technique, xiphoidectomy time, and operative and postoperative complications. Results: Thirty cases were identified to undergo xiphoidectomy. Nineteen patients were male and 11 were female, with a mean age of 51 (21–80) years. The time required for xiphoidectomy was 7–15 minutes (mean 8.7 minutes). The mean additional time required for the closure of the incision in cases with xiphoidectomy was 2 minutes. There was minimal arterial bleeding from the diaphragmatic surface in one patient, which was controlled by electrocautery. Only two patients developed wound infection. Conclusion: Performing xiphoidectomy is quite easy, after a certain learning phase. The operative time was 7–15 minutes longer due to excision of xiphoid and closure of the related defect. Minor hemorrhage was a problem during surgery. There were no early or late post-operative complications. We suggest that the procedure is beneficial in selected cases with requirement of a wider operative field or better exposure of the esophago-gastric junction during total gastrectomy for gastric cancer, and recommend removal of the xiphoid bone PMID:26985158

Benefits of xiphoidectomy in total gastrectomy: Technical note.

PubMed

Mihmanlı, Mehmet; Köksal, Hakan Mustafa; Demir, Uygar; Işıl, Rıza Gürhan

2016-01-01

The esophago-gastric junction may be challenging during total gastrectomy due to gastric cancer. This situation may compromise the security of both the dissection and anastomosis. The purpose of this study was to investigate the usefulness of xiphoidectomy to overcome this issue. The files of patients who underwent total gastrectomy + D2 lymph node dissection due to proximal gastric cancer or cardia cancer between April 2002-December 2013 were retrospectively evaluated. We assessed the outcome in patients with xiphoidectomy in addition to the midline incision in terms of xiphoidectomy technique, xiphoidectomy time, and operative and postoperative complications. Thirty cases were identified to undergo xiphoidectomy. Nineteen patients were male and 11 were female, with a mean age of 51 (21-80) years. The time required for xiphoidectomy was 7-15 minutes (mean 8.7 minutes). The mean additional time required for the closure of the incision in cases with xiphoidectomy was 2 minutes. There was minimal arterial bleeding from the diaphragmatic surface in one patient, which was controlled by electrocautery. Only two patients developed wound infection. Performing xiphoidectomy is quite easy, after a certain learning phase. The operative time was 7-15 minutes longer due to excision of xiphoid and closure of the related defect. Minor hemorrhage was a problem during surgery. There were no early or late post-operative complications. We suggest that the procedure is beneficial in selected cases with requirement of a wider operative field or better exposure of the esophago-gastric junction during total gastrectomy for gastric cancer, and recommend removal of the xiphoid bone.

48 CFR 217.208-70 - Additional clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Foreign Military Sales Commitments, when an option may be used for foreign military sale requirements. (1) Use Alternate I when the foreign military sale country is not known at the time of solicitation or..., Surge Option, in solicitations and contracts. (1) Insert the percentage of increase the option...

76 FR 54813 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

... provisions. In addition, the rule requires an independent public accountant to examine the fund's assets in... independent public accountant verify the fund's assets three times each year and prepare the certificate of examination. Commission staff estimates the annual cost for an independent public accountant to perform this...

Why Service-Learning?

ERIC Educational Resources Information Center

Speck, Bruce W.

2001-01-01

Describes two significant theoretical approaches to service learning (philanthropic and civil) so that professors are aware of two different impulses that inform service learning. In addition, addresses three critical concerns about service learning: it takes too much time and too many resources, it should not be required, and it should be…

47 CFR 18.117 - Report of interference investigation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false Report of interference investigation. 18.117 Section 18.117 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... report may be extended by the Engineer in Charge when additional time is required to put into effect the...

47 CFR 18.117 - Report of interference investigation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Report of interference investigation. 18.117 Section 18.117 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... report may be extended by the Engineer in Charge when additional time is required to put into effect the...

The President’s Budget: Overview of Structure and Timing of Submission to Congress

DTIC Science & Technology

2013-07-25

Nuclear Facilities Safety Board, Securities and Exchange Commission, and National Transportation Safety Board) are required by statute to submit...Research Service 4 Governors of the Federal Reserve System, and Federal National Mortgage Association).22 Additionally, certain agencies (e.g., Defense

14 CFR 121.523 - Flight time limitations: Crew of three or more pilots and additional airmen as required.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... It shall also provide adequate sleeping quarters on the airplane whenever an airman is scheduled to... may be aloft as a flight crewmember for more than 350 hours in any 90 consecutive days. [Doc. No. 6258...

14 CFR 121.523 - Flight time limitations: Crew of three or more pilots and additional airmen as required.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... It shall also provide adequate sleeping quarters on the airplane whenever an airman is scheduled to... may be aloft as a flight crewmember for more than 350 hours in any 90 consecutive days. [Doc. No. 6258...

14 CFR 121.523 - Flight time limitations: Crew of three or more pilots and additional airmen as required.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... It shall also provide adequate sleeping quarters on the airplane whenever an airman is scheduled to... may be aloft as a flight crewmember for more than 350 hours in any 90 consecutive days. [Doc. No. 6258...

14 CFR 121.523 - Flight time limitations: Crew of three or more pilots and additional airmen as required.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... It shall also provide adequate sleeping quarters on the airplane whenever an airman is scheduled to... may be aloft as a flight crewmember for more than 350 hours in any 90 consecutive days. [Doc. No. 6258...

14 CFR 121.523 - Flight time limitations: Crew of three or more pilots and additional airmen as required.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... It shall also provide adequate sleeping quarters on the airplane whenever an airman is scheduled to... may be aloft as a flight crewmember for more than 350 hours in any 90 consecutive days. [Doc. No. 6258...

In-Situ monitoring and modeling of metal additive manufacturing powder bed fusion

NASA Astrophysics Data System (ADS)

Alldredge, Jacob; Slotwinski, John; Storck, Steven; Kim, Sam; Goldberg, Arnold; Montalbano, Timothy

2018-04-01

One of the major challenges in metal additive manufacturing is developing in-situ sensing and feedback control capabilities to eliminate build errors and allow qualified part creation without the need for costly and destructive external testing. Previously, many groups have focused on high fidelity numerical modeling and true temperature thermal imaging systems. These approaches require large computational resources or costly hardware that requires complex calibration and are difficult to integrate into commercial systems. In addition, due to the rapid change in the state of the material as well as its surface properties, getting true temperature is complicated and difficult. Here, we describe a different approach where we implement a low cost thermal imaging solution allowing for relative temperature measurements sufficient for detecting unwanted process variability. We match this with a faster than real time qualitative model that allows the process to be rapidly modeled during the build. The hope is to combine these two, allowing for the detection of anomalies in real time, enabling corrective action to potentially be taken, or parts to be stopped immediately after the error, saving material and time. Here we describe our sensor setup, its costs and abilities. We also show the ability to detect in real time unwanted process deviations. We also show that the output of our high speed model agrees qualitatively with experimental results. These results lay the groundwork for our vision of an integrated feedback and control scheme that combines low cost, easy to use sensors and fast modeling for process deviation monitoring.

A Theory of Information Quality and a Framework for its Implementation in the Requirements Engineering Process

NASA Astrophysics Data System (ADS)

Grenn, Michael W.

This dissertation introduces a theory of information quality to explain macroscopic behavior observed in the systems engineering process. The theory extends principles of Shannon's mathematical theory of communication [1948] and statistical mechanics to information development processes concerned with the flow, transformation, and meaning of information. The meaning of requirements information in the systems engineering context is estimated or measured in terms of the cumulative requirements quality Q which corresponds to the distribution of the requirements among the available quality levels. The requirements entropy framework (REF) implements the theory to address the requirements engineering problem. The REF defines the relationship between requirements changes, requirements volatility, requirements quality, requirements entropy and uncertainty, and engineering effort. The REF is evaluated via simulation experiments to assess its practical utility as a new method for measuring, monitoring and predicting requirements trends and engineering effort at any given time in the process. The REF treats the requirements engineering process as an open system in which the requirements are discrete information entities that transition from initial states of high entropy, disorder and uncertainty toward the desired state of minimum entropy as engineering effort is input and requirements increase in quality. The distribution of the total number of requirements R among the N discrete quality levels is determined by the number of defined quality attributes accumulated by R at any given time. Quantum statistics are used to estimate the number of possibilities P for arranging R among the available quality levels. The requirements entropy H R is estimated using R, N and P by extending principles of information theory and statistical mechanics to the requirements engineering process. The information I increases as HR and uncertainty decrease, and the change in information AI needed to reach the desired state of quality is estimated from the perspective of the receiver. The HR may increase, decrease or remain steady depending on the degree to which additions, deletions and revisions impact the distribution of R among the quality levels. Current requirements trend metrics generally treat additions, deletions and revisions the same and simply measure the quantity of these changes over time. The REF evaluates the quantity of requirements changes over time, distinguishes between their positive and negative effects by calculating their impact on HR, Q, and AI, and forecasts when the desired state will be reached, enabling more accurate assessment of the status and progress of the requirements engineering effort. Results from random variable simulations suggest the REF is an improved leading indicator of requirements trends that can be readily combined with current methods. The increase in I, or decrease in H R and uncertainty, is proportional to the engineering effort E input into the requirements engineering process. The REF estimates the AE needed to transition R from their current state of quality to the desired end state or some other interim state of interest. Simulation results are compared with measured engineering effort data for Department of Defense programs published in the SE literature, and the results suggest the REF is a promising new method for estimation of AE.

The strong Bell inequalities: A proposed experimental test

NASA Technical Reports Server (NTRS)

Fry, Edward S.

1994-01-01

All previous experimental tests of Bell inequalities have required additional assumptions. The strong Bell inequalities (i.e. those requiring no additional assumptions) have never been tested. An experiment has been designed that can, for the first time, provide a definitive test of the strong Bell inequalities. Not only will the detector efficiency loophole be closed; but the locality condition will also be rigorously enforced. The experiment involves producing two Hg-199 atoms by a resonant Raman dissociation of a mercury dimer ((199)Hg2) that is in an electronic and nuclear spin singlet state. Bell inequalities can be tested by measuring angular momentum correlations between the spin one-half nuclei of the two Hg-199 atoms. The method used to make these latter measurements will be described.

[Expenditure on the Care of COPD Patients Under Everyday Conditions in Pneumological Practices Differentiated According to Patients in Chronic Care and New Patients and Severity of the Illness].

PubMed

Hellmann, A; Hering, T; Andres, J

2018-06-01

New patients in the secondary respiratory care require more time for the first consultation and place a higher diagnostic and therapeutic demand if compared to patients already in chronic care. More diagnostic procedures and patient's education by the team are required. No such burden is observed regarding differential degrees of severity of respiratory diseases, e. g. COPD. The overall demands add up to twice the demands of patients already in care. Thus the time required for the treatment of 50 new patients allows consultations for 100 patients already known in the office.As additional time and effort for new patients is not adequately represented in the German medical tax (EBM) a trend to risk selection and a preference for control patients is observed. In contrast incentives to foster treatment of new patients could be an effective measure to dramatically reduce waiting time for visits with pulmonologists. This should be achieved by changes in the German medical tax (EBM). © Georg Thieme Verlag KG Stuttgart · New York.

The 3D dynamics of the Cosserat rod as applied to continuum robotics

NASA Astrophysics Data System (ADS)

Jones, Charles Rees

2011-12-01

In the effort to simulate the biologically inspired continuum robot's dynamic capabilities, researchers have been faced with the daunting task of simulating---in real-time---the complete three dimensional dynamics of the "beam-like" structure which includes the three "stiff" degrees-of-freedom transverse and dilational shear. Therefore, researchers have traditionally limited the difficulty of the problem with simplifying assumptions. This study, however, puts forward a solution which makes no simplifying assumptions and trades off only the real-time requirement of the desired solution. The solution is a Finite Difference Time Domain method employing an explicit single step method with cheap right hands sides. The cheap right hand sides are the result of a rather ingenious formulation of the classical beam called the Cosserat rod by, first, the Cosserat brothers and, later, Stuart S. Antman which results in five nonlinear but uncoupled equations that require only multiplication and addition. The method is therefore suitable for hardware implementation thus moving the real-time requirement from a software solution to a hardware solution.

Rational reduction of periodic propagators for off-period observations.

PubMed

Blanton, Wyndham B; Logan, John W; Pines, Alexander

2004-02-01

Many common solid-state nuclear magnetic resonance problems take advantage of the periodicity of the underlying Hamiltonian to simplify the computation of an observation. Most of the time-domain methods used, however, require the time step between observations to be some integer or reciprocal-integer multiple of the period, thereby restricting the observation bandwidth. Calculations of off-period observations are usually reduced to brute force direct methods resulting in many demanding matrix multiplications. For large spin systems, the matrix multiplication becomes the limiting step. A simple method that can dramatically reduce the number of matrix multiplications required to calculate the time evolution when the observation time step is some rational fraction of the period of the Hamiltonian is presented. The algorithm implements two different optimization routines. One uses pattern matching and additional memory storage, while the other recursively generates the propagators via time shifting. The net result is a significant speed improvement for some types of time-domain calculations.

Novel priming and crosslinking systems for use with isocyanatomethacrylate dental adhesives.

PubMed

Chappelow, C C; Power, M D; Bowles, C Q; Miller, R G; Pinzino, C S; Eick, J D

2000-11-01

(a) to design, formulate and evaluate prototype primers and a crosslinking agent for use with isocyanatomethacrylate-based comonomer adhesives and (b) to establish correlations between bond strength and solubility parameter differences between the adhesives and etched dentin, and the permeability coefficients of the adhesives. Equimolar mixtures of 2-isocyanatoethyl methacrylate (IEM) and a methacrylate comonomer were formulated with tri-n-butyl borane oxide (TBBO) as the free radical initiator to have cure times of 6-10 min. Shear bond strengths to dentin were determined for each adhesive mixture (n = 7) using standard testing protocols. Shear bond strengths for the three systems were also determined after application of "reactive primers" to the dentin surface. The "reactive primers" contained 10-20 parts by weight of the respective comonomer mixture and 3.5 parts by weight TBBO in acetone. Solubility parameters difference values (delta delta) and permeability coefficients (P) were approximated for each adhesive system and correlated with shear bond strength values. Additionally, a crosslinking agent was prepared by bulk reaction of an equimolar mixture containing IEM and a methacrylate comonomer. The effects of crosslinker addition on: (a) the setting time of IEM; and (b) the setting times and initiator requirements of selected IEM/comonomer mixtures were determined. Shear bond strength values (MPa): IEM/HEMA 13.6 +/- 2.0 (no primer), 20.1 +/- 2.0 (with primer); IEM/HETMA 9.3 +/- 3.3 (no primer), 20.8 +/- 8.1 (with primer); IEM/AAEMA 13.6 +/- 1.9 (no primer), 17.3 +/- 3.2 (with primer). Also, approximated permeability coefficients showed a significant correlation (r = +0.867, p < 0.001) with shear bond strength values. Crosslinker addition studies with IEM/4-META: (a) at 5-9 mol% reduced the setting time of IEM polymerization by 79%; and (b) at 6 mol% reduced initiator level requirements 60-70% to achieve a comparable setting time, and decreased setting times by ca. 75% for a given initiator level with selected IEM/methacrylate adhesive systems. The shear bond strengths of isocyanatomethacrylate-based dental adhesives can be enhanced by using reactive primers; their setting times and initiator requirements can be improved using a dimethacrylate crosslinker. Approximated permeability coefficients may be useful as indicators of bonding performance for dentin adhesive systems.

An astrometric facility for planetary detection on the space station

NASA Technical Reports Server (NTRS)

Nishioka, Kenji; Scargle, Jeffrey D.; Givens, John J.

1987-01-01

An Astrometric Telescope Facility (ATF) for planetary detection is being studied as a potential space station initial operating capability payload. The primary science objective of this mission is the detection and study of planetary systems around other stars. In addition, the facility will be capable of other astrometric measurements such as stellar motions of other galaxies and highly precise direct measurement of stellar distance within the Milky Way Galaxy. The results of a recently completed ATF preliminary systems definition study are summarized. Results of this study indicate that the preliminary concept for the facility is fully capable of meeting the science objective without the development of any new technologies. A simple straightforward operations approach was developed for the ATF. A real-time facility control is not normally required, but does maintain a near real-time ground monitoring capability for the facility and science data stream on a full-time basis. Facility observational sequences are normally loaded once a week. In addition, the preliminary system is designed to be fail-safe and single-fault tolerant. Routine interactions by the space station crew with the ATF will not be necessary, but onboard controls are provided for crew override as required for emergencies and maintenance.

46 CFR 15.525 - Additional manning requirements for tank vessels.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Additional manning requirements for tank vessels. 15.525... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.525 Additional manning requirements for tank vessels. Parts 31 and 35 of this chapter contain additional manning requirements applicable to...

Wearable technologies for soldier first responder assessment and remote monitoring (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lee, Stephen

2017-05-01

Embedded combat medical personnel require accurate and timely biometric data to ensure appropriate life saving measures. Injured warfighter's operating in remote environments require both assessment and monitoring often while still engaged with enemy forces. Small wearable devices that can be placed on injured personnel capable of collecting essential biometric data, including the capacity to remotely deliver collected data in real-time, would allow additional medical monitoring and triage that will greatly help the medic in the battlefield. These new capabilities will provide a force multiplier through remote assessment, increased survivability, and in freeing engaged warfighter's from direct monitoring thus improving combat effectiveness and increasing situational awareness. Key questions around what information does the medic require and how effective it can be relayed to support personnel are at their early stages of development. A low power biometric wearable device capable of reliable electrocardiogram (EKG) rhythm, temperature, pulse, and other vital data collection which can provide real-time remote monitoring are in development for the Soldier.

Optimization-based manufacturing scheduling with multiple resources and setup requirements

NASA Astrophysics Data System (ADS)

Chen, Dong; Luh, Peter B.; Thakur, Lakshman S.; Moreno, Jack, Jr.

1998-10-01

The increasing demand for on-time delivery and low price forces manufacturer to seek effective schedules to improve coordination of multiple resources and to reduce product internal costs associated with labor, setup and inventory. This study describes the design and implementation of a scheduling system for J. M. Product Inc. whose manufacturing is characterized by the need to simultaneously consider machines and operators while an operator may attend several operations at the same time, and the presence of machines requiring significant setup times. The scheduling problem with these characteristics are typical for many manufacturers, very difficult to be handled, and have not been adequately addressed in the literature. In this study, both machine and operators are modeled as resources with finite capacities to obtain efficient coordination between them, and an operator's time can be shared by several operations at the same time to make full use of the operator. Setups are explicitly modeled following our previous work, with additional penalties on excessive setups to reduce setup costs and avoid possible scraps. An integer formulation with a separable structure is developed to maximize on-time delivery of products, low inventory and small number of setups. Within the Lagrangian relaxation framework, the problem is decomposed into individual subproblems that are effectively solved by using dynamic programming with additional penalties embedded in state transitions. Heuristics is then developed to obtain a feasible schedule following on our previous work with new mechanism to satisfy operator capacity constraints. The method has been implemented using the object-oriented programming language C++ with a user-friendly interface, and numerical testing shows that the method generates high quality schedules in a timely fashion. Through simultaneous consideration of machines and operators, machines and operators are well coordinated to facilitate the smooth flow of parts through the system. The explicit modeling of setups and the associated penalties let parts with same setup requirements clustered together to avoid excessive setups.

A collaborative approach to lean laboratory workstation design reduces wasted technologist travel.

PubMed

Yerian, Lisa M; Seestadt, Joseph A; Gomez, Erron R; Marchant, Kandice K

2012-08-01

Lean methodologies have been applied in many industries to reduce waste. We applied Lean techniques to redesign laboratory workstations with the aim of reducing the number of times employees must leave their workstations to complete their tasks. At baseline in 68 workflows (aggregates or sequence of process steps) studied, 251 (38%) of 664 tasks required workers to walk away from their workstations. After analysis and redesign, only 59 (9%) of the 664 tasks required technologists to leave their workstations to complete these tasks. On average, 3.4 travel events were removed for each workstation. Time studies in a single laboratory section demonstrated that workers spend 8 to 70 seconds in travel each time they step away from the workstation. The redesigned workstations will allow employees to spend less time travelling around the laboratory. Additional benefits include employee training in waste identification, improved overall laboratory layout, and identification of other process improvement opportunities in our laboratory.

A Spatial-frequency Method for Analyzing Antenna-to-Probe Interactions in Near-field Antenna Measurements.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brock, Billy C.

The measurement of the radiation characteristics of an antenna on a near-field range requires that the antenna under test be located very close to the near-field probe. Although the direct coupling is utilized for characterizing the near field, this close proximity also presents the opportunity for significant undesired interactions (for example, reflections) to occur between the antenna and the near-field probe. When uncompensated, these additional interactions will introduce error into the measurement, increasing the uncertainty in the final gain pattern obtained through the near-field-to-far-field transformation. Quantifying this gain-uncertainty contribution requires quantifying the various additional interactions. A method incorporating spatial-frequency analysismore » is described which allows the dominant interaction contributions to be easily identified and quantified. In addition to identifying the additional antenna-to-probe interactions, the method also allows identification and quantification of interactions with other nearby objects within the measurement room. Because the method is a spatial-frequency method, wide-bandwidth data is not required, and it can be applied even when data is available at only a single temporal frequency. This feature ensures that the method can be applied to narrow-band antennas, where a similar time-domain analysis would not be possible. - 3 - - 4 -« less

Random phase detection in multidimensional NMR.

PubMed

Maciejewski, Mark W; Fenwick, Matthew; Schuyler, Adam D; Stern, Alan S; Gorbatyuk, Vitaliy; Hoch, Jeffrey C

2011-10-04

Despite advances in resolution accompanying the development of high-field superconducting magnets, biomolecular applications of NMR require multiple dimensions in order to resolve individual resonances, and the achievable resolution is typically limited by practical constraints on measuring time. In addition to the need for measuring long evolution times to obtain high resolution, the need to distinguish the sign of the frequency constrains the ability to shorten measuring times. Sign discrimination is typically accomplished by sampling the signal with two different receiver phases or by selecting a reference frequency outside the range of frequencies spanned by the signal and then sampling at a higher rate. In the parametrically sampled (indirect) time dimensions of multidimensional NMR experiments, either method imposes an additional factor of 2 sampling burden for each dimension. We demonstrate that by using a single detector phase at each time sample point, but randomly altering the phase for different points, the sign ambiguity that attends fixed single-phase detection is resolved. Random phase detection enables a reduction in experiment time by a factor of 2 for each indirect dimension, amounting to a factor of 8 for a four-dimensional experiment, albeit at the cost of introducing sampling artifacts. Alternatively, for fixed measuring time, random phase detection can be used to double resolution in each indirect dimension. Random phase detection is complementary to nonuniform sampling methods, and their combination offers the potential for additional benefits. In addition to applications in biomolecular NMR, random phase detection could be useful in magnetic resonance imaging and other signal processing contexts.

Long-term outcomes after primary failures of artificial urinary sphincter implantation.

PubMed

Wang, Rou; McGuire, Edward J; He, Chang; Faerber, Gary J; Latini, Jerilyn M

2012-04-01

To assess our institutional outcomes after primary artificial urinary sphincter (AUS) failures. From 1985 to 2010, a total of 149 patients underwent 318 primary and additional AUS procedures. We classified additional procedures as revisions, replacements, or explantations. At a median of 52 months (range, 6-250 months), 53% of patients had required at least 1 additional procedure beyond their initial implantation. These included 106 (63%) revisions, 42 (24.9%) explantations, and 21 (12.4%) replacements. The most common revision was reservoir upsizing (37/106). Reasons for first revision included recurrent incontinence (56.7%), mechanical malfunction (22%), and infection or erosion (18.6%). Explantations were performed primarily for infection and erosion (64.3%). Median time to first revision was 20.1 months (range, 0.1-173 months) after implantation, with a median of 9.5 months (range, 1-102 months) between revisions. Explantation occurred at a median of 22 months (range, 1-221 months) after implant, and subsequent replacement at a median of 33.6 months (range, 2-138 months). At 5 years, 28/83 (33.7%) patients had undergone no additional procedures. Patients with previous radiation were more likely to experience infection (P = .03; OR 3.99; 95% CI 1.03-15.42). Patients with previous myocardial infarction were more likely to experience erosion (P = .04; OR 2.29; 95% CI 1.05-5.02), and obese patients were more likely to experience mechanical malfunction (P = .04; OR 2.62; 95% CI 1.07-6.4). More than half of patients with an AUS will require additional procedures, most likely revision. Radiation, previous myocardial infarction, and obesity are linked to complications. Median time to first revision or explantation is slightly less than 2 years, indicating that long-term follow-up is required after initial implantation. Copyright © 2012 Elsevier Inc. All rights reserved.

Ladder operators for the Klein-Gordon equation with a scalar curvature term

NASA Astrophysics Data System (ADS)

Mück, Wolfgang

2018-01-01

Recently, Cardoso, Houri and Kimura constructed generalized ladder operators for massive Klein-Gordon scalar fields in space-times with conformal symmetry. Their construction requires a closed conformal Killing vector, which is also an eigenvector of the Ricci tensor. Here, a similar procedure is used to construct generalized ladder operators for the Klein-Gordon equation with a scalar curvature term. It is proven that a ladder operator requires the existence of a conformal Killing vector, which must satisfy an additional property. This property is necessary and sufficient for the construction of a ladder operator. For maximally symmetric space-times, the results are equivalent to those of Cardoso, Houri and Kimura.

Microwave Protocols for Paraffin Microtechnique and In Situ Localization in Plants

NASA Astrophysics Data System (ADS)

Schichnes, Denise; Nemson, Jeff; Sohlberg, Lorraine; Ruzin, Steven E.

1998-10-01

: We have developed a microwave protocol for a paraffin-embedding microtechnique of the shoot apical meristem of ZEA MAYS and have successfully applied this protocol to other plant tissues. This protocol decreases the time required for all aspects of microtechnique tissue processing, including fixation (24 hr to 15 min), dehydration (73 hr to 10 min), and infiltration (96 hr to 3 hr). Additionally, the time required to adhere paraffin ribbons to gelatin-coated slides and for the Johanson's safranin O, fast green FCF staining protocol has been significantly decreased. Using this technique, the quality of tissue preservation and subsequent in situ localization of KNOTTED mRNA was increased by using microwaves.

Towards Solving the Mixing Problem in the Decomposition of Geophysical Time Series by Independent Component Analysis

NASA Technical Reports Server (NTRS)

Aires, Filipe; Rossow, William B.; Chedin, Alain; Hansen, James E. (Technical Monitor)

2000-01-01

The use of the Principal Component Analysis technique for the analysis of geophysical time series has been questioned in particular for its tendency to extract components that mix several physical phenomena even when the signal is just their linear sum. We demonstrate with a data simulation experiment that the Independent Component Analysis, a recently developed technique, is able to solve this problem. This new technique requires the statistical independence of components, a stronger constraint, that uses higher-order statistics, instead of the classical decorrelation a weaker constraint, that uses only second-order statistics. Furthermore, ICA does not require additional a priori information such as the localization constraint used in Rotational Techniques.

The MGTX Experience: Challenges in Planning and Executing an International, Multicenter Clinical Trial

PubMed Central

Aban, Inmaculada B.; Wolfe, Gil I.; Cutter, Gary R.; Kaminski, Henry J.; Jaretzki, Alfred; Minisman, Greg; Conwit, Robin; Newsom-Davis, John

2008-01-01

We present our experience planning and launching a multinational, NIH/NINDS funded study of thymectomy in myasthenia gravis. We highlight the additional steps required for international sites and analyze and contrast the time investment required to bring U.S. and non-U.S. sites into full regulatory compliance. Results show the mean time for non- U.S. centers to achieve regulatory approval was significantly longer (mean 13.4 ± 0.96 months) than for U.S. sites (9.67 ± 0.74 months; p = 0.003, t-test). The delay for non- U.S. sites was mainly attributable to Federalwide Assurance certification and State Department clearance. PMID:18675464

An integrated decision support system for diagnosing and managing patients with community-acquired pneumonia.

PubMed Central

Aronsky, D.; Haug, P. J.

1999-01-01

Decision support systems that integrate guidelines have become popular applications to reduce variation and deliver cost-effective care. However, adverse characteristics of decision support systems, such as additional and time-consuming data entry or manually identifying eligible patients, result in a "behavioral bottleneck" that prevents decision support systems to become part of the clinical routine. This paper describes the design and the implementation of an integrated decision support system that explores a novel approach for bypassing the behavioral bottleneck. The real-time decision support system does not require health care providers to enter additional data and consists of a diagnostic and a management component. Images Fig. 1 Fig. 2 Fig. 3 PMID:10566348

Separating OR, SUM, and XOR Circuits.

PubMed

Find, Magnus; Göös, Mika; Järvisalo, Matti; Kaski, Petteri; Koivisto, Mikko; Korhonen, Janne H

2016-08-01

Given a boolean n × n matrix A we consider arithmetic circuits for computing the transformation x ↦ Ax over different semirings. Namely, we study three circuit models: monotone OR-circuits, monotone SUM-circuits (addition of non-negative integers), and non-monotone XOR-circuits (addition modulo 2). Our focus is on separating OR-circuits from the two other models in terms of circuit complexity: We show how to obtain matrices that admit OR-circuits of size O ( n ), but require SUM-circuits of size Ω( n 3/2 /log 2 n ).We consider the task of rewriting a given OR-circuit as a XOR-circuit and prove that any subquadratic-time algorithm for this task violates the strong exponential time hypothesis.

The impact of preventable disruption on the operative time for minimally invasive surgery.

PubMed

Al-Hakim, Latif

2011-10-01

Current ergonomic studies show that disruption exposes surgical teams to stress and musculoskeletal disorders. This study considers minimally invasive surgery as a sociotechnical process subjected to a variety of disruption events other than those recognized by ergonomic science. The research takes into consideration the impact of preventable disruption on operating time rather than on the physical and emotional status of the surgical team. Events inside operating rooms that disturbed operative time were recorded for 17 minimally invasive surgeries. The disruption events were classified into four main areas: prerequisite requirements, work design, communication during surgery, and other. Each area was further classified according to sources of disruption. Altogether, 11 sources of disruption were identified: patient record, protocol and policy, surgical requirements and surgeon preferences, operating table and patient positioning, arrangement of instruments, lighting, monitor, clothing, surgical teamwork, coordination, and other. Disruption prolonged operative time by more than 32%. Teamwork forms the main source of disruption followed by operating table and patient positioning and arrangement of instruments. These three sources represented approximately 20% of operative time. Failure to follow principles of work design had a significant negative impact, lengthening operative time by approximately 15%. Although lighting and monitors had a relatively small impact on operative time, these factors could create inconvenience and stress within the surgical teams. In addition, the effect of failure to follow surgical protocols and policies or having incomplete patient records may have a limited effect on operative time but could have serious consequences. This report demonstrates that preventable disruption caused an increase in operative time and forced surgeons and patients to endure unnecessary delay of more than 32%. Such additional time could be used to deal with the pressure of emergency cases and to reduce waiting lists for elective surgery.

Geometry and Grid Modeling for Numerical Simulation

DTIC Science & Technology

2005-06-01

which makes them particularly vexing to beginners . In addition, they are expensive in terms of memory requirements and compile times. 3.1.4 TSTT The...F77, Python , or Fortran90 (beta). It supports drivers written in C, C++, F77, Python , Java or Fortran90 (beta). It is supported currently on

21 CFR 1311.116 - Additional requirements for biometrics.

Code of Federal Regulations, 2011 CFR

2011-04-01

... controlled substances. (f) The biometric subsystem must store device ID data at enrollment (i.e., biometric registration) with the biometric data and verify the device ID at the time of authentication to the electronic prescription application. (g) The biometric subsystem must protect the biometric data (raw data or templates...

21 CFR 1311.116 - Additional requirements for biometrics.

Code of Federal Regulations, 2010 CFR

2010-04-01

... controlled substances. (f) The biometric subsystem must store device ID data at enrollment (i.e., biometric registration) with the biometric data and verify the device ID at the time of authentication to the electronic prescription application. (g) The biometric subsystem must protect the biometric data (raw data or templates...

13 CFR 127.504 - What additional requirements must a concern satisfy to submit an offer on an EDWOSB or WOSB...

Code of Federal Regulations, 2012 CFR

2012-01-01

... certifications on ORCA are accurate and complete at the time it submits its offer to the contracting officer... NAICS code assigned to the contract; (2) It is listed on CCR and ORCA as an EDWOSB or WOSB; and (3...

13 CFR 127.504 - What additional requirements must a concern satisfy to submit an offer on an EDWOSB or WOSB...

Code of Federal Regulations, 2013 CFR

2013-01-01

... certifications on ORCA are accurate and complete at the time it submits its offer to the contracting officer... NAICS code assigned to the contract; (2) It is listed on CCR and ORCA as an EDWOSB or WOSB; and (3...

A Meta-Analysis of Individualized Instruction in Dental Education.

ERIC Educational Resources Information Center

Dacanay, Lakshmi S; Cohen, Peter A.

1992-01-01

Meta-analysis of 34 comparative studies on conventional vs. individualized instruction (II) found most favored the latter but with small-moderate overall effect. Pacing had significant effect, with teacher-pacing more effective than student-paced learning. On average, II required less time than conventional teaching. Additional research on this…

Real-Time Computer-Mediated Communication: Email and Instant Messaging Simulation

ERIC Educational Resources Information Center

Newman, Amy

2007-01-01

As computer-mediated communication becomes increasingly prevalent in the workplace, students need to apply effective writing principles to today's technologies. Email, in particular, requires interns and new hires to manage incoming messages, use an appropriate tone, and craft clear, concise messages. In addition, with instant messaging (IM)…

46 CFR 62.50-30 - Additional requirements for periodically unattended machinery plants.

Code of Federal Regulations, 2013 CFR

2013-10-01

... automatically and continuously charged. (e) Assistance-needed alarm. The engineer's assistance-needed alarm (see... period of time necessary for an engineer to respond at the ECC from the machinery spaces or engineers... engineers' accommodations. Other than fire or flooding alarms, this may be accomplished by summarized visual...

46 CFR 62.50-30 - Additional requirements for periodically unattended machinery plants.

Code of Federal Regulations, 2011 CFR

2011-10-01

... automatically and continuously charged. (e) Assistance-needed alarm. The engineer's assistance-needed alarm (see... period of time necessary for an engineer to respond at the ECC from the machinery spaces or engineers... engineers' accommodations. Other than fire or flooding alarms, this may be accomplished by summarized visual...

46 CFR 62.50-30 - Additional requirements for periodically unattended machinery plants.

Code of Federal Regulations, 2012 CFR

2012-10-01

... automatically and continuously charged. (e) Assistance-needed alarm. The engineer's assistance-needed alarm (see... period of time necessary for an engineer to respond at the ECC from the machinery spaces or engineers... engineers' accommodations. Other than fire or flooding alarms, this may be accomplished by summarized visual...

46 CFR 62.50-30 - Additional requirements for periodically unattended machinery plants.

Code of Federal Regulations, 2010 CFR

2010-10-01

... automatically and continuously charged. (e) Assistance-needed alarm. The engineer's assistance-needed alarm (see... period of time necessary for an engineer to respond at the ECC from the machinery spaces or engineers... engineers' accommodations. Other than fire or flooding alarms, this may be accomplished by summarized visual...

40 CFR 26.1101 - To what does this subpart apply?

Code of Federal Regulations, 2012 CFR

2012-07-01

... HUMAN SUBJECTS Basic Ethical Requirements for Third-Party Human Research for Pesticides Involving... initiated after April 7, 2006 involving intentional exposure of a human subject if, at any time prior to... additional protections for human subjects. (e) This subpart does not affect any State or local laws or...

40 CFR 26.1101 - To what does this subpart apply?

Code of Federal Regulations, 2011 CFR

2011-07-01

... HUMAN SUBJECTS Basic Ethical Requirements for Third-Party Human Research for Pesticides Involving... initiated after April 7, 2006 involving intentional exposure of a human subject if, at any time prior to... additional protections for human subjects. (e) This subpart does not affect any State or local laws or...

78 FR 76888 - MAP-21 Comprehensive Truck Size and Weight Limits Study Materials

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

... Weight Limits Study Materials AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of...) Comprehensive Truck Size and Weight Limits Study, which were referenced in a notice published on November 29... commenting additional time to submit comments while maintaining the schedule required to deliver this study...

Classroom Activities and Demonstrations for Use in Behavioral Science Courses.

ERIC Educational Resources Information Center

Cology, Lorry J.

This compilation provides descriptions of and resource materials for 25 classroom activities or demonstrations for behavioral science courses. For each activity, the following information is provided: subject area, source, time required and materials needed. In addition, discussion questions and comments on the value and use of the activities are…

FLUE GAS DESULFURIZATION: THE STATE OF THE ART

EPA Science Inventory

Coal-fired electricity-generating plants may use SO2 scrubbers to meet the requirements of Phase II of the Acid Rain SO2 Reduction Program. Additionally, the use of scrubbers can result in reduction of Hg and other emissions from combustion sources. It is timely, therefore, to ex...

76 FR 43960 - NARA Records Reproduction Fees

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... transferred to NARA and maintain its fee schedule on NARA's Web site http://www.archives.gov . The proposed... document is faint or too dark, it requires additional time to obtain a readable image. In TABLE 1 below... our Web site ( http://www.archives.gov ) annually when announcing that records reproduction fees will...

Developing Study Stations on Your School Site.

ERIC Educational Resources Information Center

Ohio State Dept. of Natural Resources, Columbus. Office of Information and Education.

The school site is a convenient location for study stations since it is available for short periods of time and can be used consistently. Special preparations, such as transportation, required for off-site fieldtrips can be eliminated. In addition, on-site activities provide students with concrete experiences necessary to understand difficult…

Timing and Spectroscopy Requirements for a Plastic Scintillating Fiber Bundle Time-of-Flight Neutron Spectrometer

DTIC Science & Technology

2013-12-01

tight aluminum box internal view. Each SiPMT is held securely in each aluminum jig with nylon washers and screws. The threaded rod extends length-wise...hole in the aluminum jig located between the threaded rod and nylon screw is the hole where the single BCF-12 scintillating fiber would be placed to...additional pixel firing from the SiPMT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 42 A typical Hamamatsu

NATOs Relevance to United States Enduring National Interests Time to Remove the Training Wheels but Continue to Hold the Handle Bars

DTIC Science & Technology

2016-06-10

shift in the United States’ view of its role within the alliance in the future. Additional research of published documentation on the current and...the Joint Advanced Warfighting School in partial satisfaction of the requirements of a Master of Science Degree in Joint Campaign Planning and...resources so I could conduct the detailed research required for this thesis. Lastly, a special thanks to the “Bulldogs” of Seminar 3, your thoughts

Requirements and Architecture Specification of the Joint Multi-Role (JMR) Joint Common Architecture (JCA) Demonstration System

DTIC Science & Technology

2015-12-01

response time re- quirements and in additional calibration requirements for DCFM that may create unexpected la - tency and latency jitter that can...manage the flight path of the aircraft. For more information about sensor correlation and fusion processes, the Air University New World Vistas ...request/reply actions. We specify its la - tency as a minimum and maximum of 300 ms.  SADataServiceProtocol: an abstraction of the SA data service as a

The Algorithm Theoretical Basis Document for Level 1A Processing

NASA Technical Reports Server (NTRS)

Jester, Peggy L.; Hancock, David W., III

2012-01-01

The first process of the Geoscience Laser Altimeter System (GLAS) Science Algorithm Software converts the Level 0 data into the Level 1A Data Products. The Level 1A Data Products are the time ordered instrument data converted from counts to engineering units. This document defines the equations that convert the raw instrument data into engineering units. Required scale factors, bias values, and coefficients are defined in this document. Additionally, required quality assurance and browse products are defined in this document.

Elective change of surgeon during the OR day has an operationally negligible impact on turnover time.

PubMed

Austin, Thomas M; Lam, Humphrey V; Shin, Naomi S; Daily, Bethany J; Dunn, Peter F; Sandberg, Warren S

2014-08-01

To compare turnover times for a series of elective cases with surgeons following themselves with turnover times for a series of previously scheduled elective procedures for which the succeeding surgeon differed from the preceding surgeon. Retrospective cohort study. University-affiliated teaching hospital. The operating room (OR) statistical database was accessed to gather 32 months of turnover data from a large academic institution. Turnover time data for the same-surgeon and surgeon-swap groups were batched by month to minimize autocorrelation and achieve data normalization. Two-way analysis of variance (ANOVA) using the monthly batched data was performed with surgeon swapping and changes in procedure category as variables of turnover time. Similar analyses were performed using individual surgical services, hourly time intervals during the surgical day, and turnover frequency per OR as additional covariates to surgeon swapping. The mean (95% confidence interval [CI]) same-surgeon turnover time was 43.6 (43.2 - 44.0) minutes versus 51.0 (50.5 - 51.6) minutes for a planned surgeon swap (P < 0.0001). This resulted in a difference (95% CI) of 7.4 (6.8 - 8.1) minutes. The exact increase in turnover time was dependent on surgical service, change in subsequent procedure type, time of day when the turnover occurred, and turnover frequency. The investigated institution averages 2.5 cases per OR per day. The cumulative additional turnover time (far less than one hour per OR per day) for switching surgeons definitely does not allow the addition of another elective procedure if the difference could be eliminated. A flexible scheduling policy allowing surgeon swapping rather than requiring full blocks incurs minimal additional staffed time during the OR day while allowing the schedule to be filled with available elective cases. Copyright © 2014 Elsevier Inc. All rights reserved.

Enzymatic hydrolysis and fermentation of corn for fuel alcohol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mullins, J.T.

1985-01-01

The integration of enzyme saccharification with fermentation reduces the total time required to produce acceptable levels of ethanol. The use of a more concentrated mash (84.8 L total mash/bu corn) results in a 26.6% increase in ethanol productivity and a 21.4% increase in beer ethanol concentration compared to standard corn mash (96.6 L total mash/bu corn). Thus, the energy requirement and cost of distillation can be reduced. The addition of waste cola syrup at 30 g invert sugar/L total mash gave a 19% increase in ethanol concentration in the final beer and required only a small increase in period ofmore » fermentation. Surplus laundry starch can replace 30-50% of the weight of corn normally used in fermentation without influencing ethanol production or the time required for fermentation. Both of these waste materials reduce the unit cost of ethanol and demonstrate the value of such substances in ethanol systems.« less

The implementation of multiple interprofessional integrated modules by health sciences faculty in Chile.

PubMed

Castillo-Parra, Silvana; Oyarzo Torres, Sandra; Espinoza Barrios, Mónica; Rojas-Serey, Ana María; Maya, Juan Diego; Sabaj Diez, Valeria; Aliaga Castillo, Verónica; Castillo Niño, Manuel; Romero Romero, Luis; Foster, Jennifer; Hawes Barrios, Gustavo

2017-11-01

Multiple interprofessional integrated modules (MIIM) 1 and 2 are two required, cross-curricular courses developed by a team of health professions faculty, as well as experts in education, within the Faculty of Medicine of the University of Chile. MIIM 1 focused on virtual cases requiring team decision-making in real time. MIIM 2 focused on a team-based community project. The evaluation of MIIM included student, teacher, and coordinator perspectives. To explore the perceptions of this interprofessional experience quantitative data in the form of standardised course evaluations regarding teaching methodology, interpersonal relations and the course organisation and logistics were gathered. In addition, qualitative perceptions were collected from student focus groups and meetings with tutors and coordinators. Between 2010 and 2014, 881 students enrolled in MIIM. Their evaluation scores rated interpersonal relations most highly, followed by organisation and logistics, and then teaching methodology. A key result was the learning related to interprofessional team work by the teaching coordinators, as well as the participating faculty. The strengths of this experience included student integration and construction of new knowledge, skill development in making decisions, and collective self-learning. Challenges included additional time management and tutors' role. This work requires valuation of an alternative way of learning, which is critical for the performance of future health professionals.

Clinical usefulness of augmented reality using infrared camera based real-time feedback on gait function in cerebral palsy: a case study

PubMed Central

Lee, Byoung-Hee

2016-01-01

[Purpose] This study investigated the effects of real-time feedback using infrared camera recognition technology-based augmented reality in gait training for children with cerebral palsy. [Subjects] Two subjects with cerebral palsy were recruited. [Methods] In this study, augmented reality based real-time feedback training was conducted for the subjects in two 30-minute sessions per week for four weeks. Spatiotemporal gait parameters were used to measure the effect of augmented reality-based real-time feedback training. [Results] Velocity, cadence, bilateral step and stride length, and functional ambulation improved after the intervention in both cases. [Conclusion] Although additional follow-up studies of the augmented reality based real-time feedback training are required, the results of this study demonstrate that it improved the gait ability of two children with cerebral palsy. These findings suggest a variety of applications of conservative therapeutic methods which require future clinical trials. PMID:27190489

Real-time simulation of a Doubly-Fed Induction Generator based wind power system on eMEGASimRTM Real-Time Digital Simulator

NASA Astrophysics Data System (ADS)

Boakye-Boateng, Nasir Abdulai

The growing demand for wind power integration into the generation mix prompts the need to subject these systems to stringent performance requirements. This study sought to identify the required tools and procedures needed to perform real-time simulation studies of Doubly-Fed Induction Generator (DFIG) based wind generation systems as basis for performing more practical tests of reliability and performance for both grid-connected and islanded wind generation systems. The author focused on developing a platform for wind generation studies and in addition, the author tested the performance of two DFIG models on the platform real-time simulation model; an average SimpowerSystemsRTM DFIG wind turbine, and a detailed DFIG based wind turbine using ARTEMiSRTM components. The platform model implemented here consists of a high voltage transmission system with four integrated wind farm models consisting in total of 65 DFIG based wind turbines and it was developed and tested on OPAL-RT's eMEGASimRTM Real-Time Digital Simulator.

Achieving Ships Mission Flexibility Through Designing, Printing And Operating Unmanned Systems With Additive Manufacturing And Delayed Differentiation

DTIC Science & Technology

2016-09-01

the UAV’s reliability in fulfilling the mission as well as the build- time of the UAV. 14. SUBJECT TERMS design , print and operate, DPO...previously. There are opportunities to work on the design of the UAV to reduce the cognitive workload of the service member and time required to “print” and...the need arises to tailor the UAV for the specific mission. The modification of an existing design is expected to take a much shorter time than the

Additive Manufacturing in Production: A Study Case Applying Technical Requirements

NASA Astrophysics Data System (ADS)

Ituarte, Iñigo Flores; Coatanea, Eric; Salmi, Mika; Tuomi, Jukka; Partanen, Jouni

Additive manufacturing (AM) is expanding the manufacturing capabilities. However, quality of AM produced parts is dependent on a number of machine, geometry and process parameters. The variability of these parameters affects the manufacturing drastically and therefore standardized processes and harmonized methodologies need to be developed to characterize the technology for end use applications and enable the technology for manufacturing. This research proposes a composite methodology integrating Taguchi Design of Experiments, multi-objective optimization and statistical process control, to optimize the manufacturing process and fulfil multiple requirements imposed to an arbitrary geometry. The proposed methodology aims to characterize AM technology depending upon manufacturing process variables as well as to perform a comparative assessment of three AM technologies (Selective Laser Sintering, Laser Stereolithography and Polyjet). Results indicate that only one machine, laser-based Stereolithography, was feasible to fulfil simultaneously macro and micro level geometrical requirements but mechanical properties were not at required level. Future research will study a single AM system at the time to characterize AM machine technical capabilities and stimulate pre-normative initiatives of the technology for end use applications.

Effect of calcium formate as an additive on desulfurization in power plants.

PubMed

Li, Zhenhua; Xie, Chunfang; Lv, Jing; Zhai, Ruiguo

2018-05-01

SO 2 in flue gas needs to be eliminated to alleviate air pollution. As the quality of coal decreases and environmental standard requirements become more stringent, the high-efficiency desulfurization of flue gas faces more and more challenges. As an economical and environmentally friendly solution, the effect of calcium formate as an additive on desulfurization efficiency in the wet flue gas desulfurization (WFGD) process was studied for the first time. Improvement of the desulfurization efficiency was achieved with limited change in pH after calcium formate was added into the reactor, and it was found to work better than other additives tested. The positive effects were further verified in a power plant, which showed that adding calcium formate could promote the dissolution of calcium carbonate, accelerate the growth of gypsum crystals and improve the efficiency of desulfurization. Thus, calcium formate was proved to be an effective additive and can potentially be used to reduce the amount of limestone slurry required, as well as the energy consumption and operating costs in industrial desulfurization. Copyright © 2017. Published by Elsevier B.V.

Incremental analysis of the reengineering of an outpatient billing process: an empirical study in a public hospital

PubMed Central

2013-01-01

Background A smartcard is an integrated circuit card that provides identification, authentication, data storage, and application processing. Among other functions, smartcards can serve as credit and ATM cards and can be used to pay various invoices using a ‘reader’. This study looks at the unit cost and activity time of both a traditional cash billing service and a newly introduced smartcard billing service in an outpatient department in a hospital in Taipei, Taiwan. Methods The activity time required in using the cash billing service was determined via a time and motion study. A cost analysis was used to compare the unit costs of the two services. A sensitivity analysis was also performed to determine the effect of smartcard use and number of cashier windows on incremental cost and waiting time. Results Overall, the smartcard system had a higher unit cost because of the additional service fees and business tax, but it reduced patient waiting time by at least 8 minutes. Thus, it is a convenient service for patients. In addition, if half of all outpatients used smartcards to pay their invoices, along with four cashier windows for cash payments, then the waiting time of cash service users could be reduced by approximately 3 minutes and the incremental cost would be close to breaking even (even though it has a higher overall unit cost that the traditional service). Conclusions Traditional cash billing services are time consuming and require patients to carry large sums of money. Smartcard services enable patients to pay their bill immediately in the outpatient clinic and offer greater security and convenience. The idle time of nurses could also be reduced as they help to process smartcard payments. A reduction in idle time reduces hospital costs. However, the cost of the smartcard service is higher than the cash service and, as such, hospital administrators must weigh the costs and benefits of introducing a smartcard service. In addition to the obvious benefits of the smartcard service, there is also scope to extend its use in a hospital setting to include the notification of patient arrival and use in other departments. PMID:23763904

Incremental analysis of the reengineering of an outpatient billing process: an empirical study in a public hospital.

PubMed

Chu, Kuan-Yu; Huang, Chunmin

2013-06-13

A smartcard is an integrated circuit card that provides identification, authentication, data storage, and application processing. Among other functions, smartcards can serve as credit and ATM cards and can be used to pay various invoices using a 'reader'. This study looks at the unit cost and activity time of both a traditional cash billing service and a newly introduced smartcard billing service in an outpatient department in a hospital in Taipei, Taiwan. The activity time required in using the cash billing service was determined via a time and motion study. A cost analysis was used to compare the unit costs of the two services. A sensitivity analysis was also performed to determine the effect of smartcard use and number of cashier windows on incremental cost and waiting time. Overall, the smartcard system had a higher unit cost because of the additional service fees and business tax, but it reduced patient waiting time by at least 8 minutes. Thus, it is a convenient service for patients. In addition, if half of all outpatients used smartcards to pay their invoices, along with four cashier windows for cash payments, then the waiting time of cash service users could be reduced by approximately 3 minutes and the incremental cost would be close to breaking even (even though it has a higher overall unit cost that the traditional service). Traditional cash billing services are time consuming and require patients to carry large sums of money. Smartcard services enable patients to pay their bill immediately in the outpatient clinic and offer greater security and convenience. The idle time of nurses could also be reduced as they help to process smartcard payments. A reduction in idle time reduces hospital costs. However, the cost of the smartcard service is higher than the cash service and, as such, hospital administrators must weigh the costs and benefits of introducing a smartcard service. In addition to the obvious benefits of the smartcard service, there is also scope to extend its use in a hospital setting to include the notification of patient arrival and use in other departments.

A Semiquantitative Framework for Gene Regulatory Networks: Increasing the Time and Quantitative Resolution of Boolean Networks

PubMed Central

Kerkhofs, Johan; Geris, Liesbet

2015-01-01

Boolean models have been instrumental in predicting general features of gene networks and more recently also as explorative tools in specific biological applications. In this study we introduce a basic quantitative and a limited time resolution to a discrete (Boolean) framework. Quantitative resolution is improved through the employ of normalized variables in unison with an additive approach. Increased time resolution stems from the introduction of two distinct priority classes. Through the implementation of a previously published chondrocyte network and T helper cell network, we show that this addition of quantitative and time resolution broadens the scope of biological behaviour that can be captured by the models. Specifically, the quantitative resolution readily allows models to discern qualitative differences in dosage response to growth factors. The limited time resolution, in turn, can influence the reachability of attractors, delineating the likely long term system behaviour. Importantly, the information required for implementation of these features, such as the nature of an interaction, is typically obtainable from the literature. Nonetheless, a trade-off is always present between additional computational cost of this approach and the likelihood of extending the model’s scope. Indeed, in some cases the inclusion of these features does not yield additional insight. This framework, incorporating increased and readily available time and semi-quantitative resolution, can help in substantiating the litmus test of dynamics for gene networks, firstly by excluding unlikely dynamics and secondly by refining falsifiable predictions on qualitative behaviour. PMID:26067297

Degradable transportation network with the addition of electric vehicles: Network equilibrium analysis

PubMed Central

Zhang, Rui; Yao, Enjian; Yang, Yang

2017-01-01

Introducing electric vehicles (EVs) into urban transportation network brings higher requirement on travel time reliability and charging reliability. Specifically, it is believed that travel time reliability is a key factor influencing travelers’ route choice. Meanwhile, due to the limited cruising range, EV drivers need to better learn about the required energy for the whole trip to make decisions about whether charging or not and where to charge (i.e., charging reliability). Since EV energy consumption is highly related to travel speed, network uncertainty affects travel time and charging demand estimation significantly. Considering the network uncertainty resulted from link degradation, which influences the distribution of travel demand on transportation network and the energy demand on power network, this paper aims to develop a reliability-based network equilibrium framework for accommodating degradable road conditions with the addition of EVs. First, based on the link travel time distribution, the mean and variance of route travel time and monetary expenses related to energy consumption are deduced, respectively. And the charging time distribution of EVs with charging demand is also estimated. Then, a nested structure is considered to deal with the difference of route choice behavior derived by the different uncertainty degrees between the routes with and without degradable links. Given the expected generalized travel cost and a psychological safety margin, a traffic assignment model with the addition of EVs is formulated. Subsequently, a heuristic solution algorithm is developed to solve the proposed model. Finally, the effects of travelers’ risk attitude, network degradation degree, and EV penetration rate on network performance are illustrated through an example network. The numerical results show that the difference of travelers’ risk attitudes does have impact on the route choice, and the widespread adoption of EVs can cut down the total system travel cost effectively when the transportation network is more reliable. PMID:28886167

Degradable transportation network with the addition of electric vehicles: Network equilibrium analysis.

PubMed

Zhang, Rui; Yao, Enjian; Yang, Yang

2017-01-01

Introducing electric vehicles (EVs) into urban transportation network brings higher requirement on travel time reliability and charging reliability. Specifically, it is believed that travel time reliability is a key factor influencing travelers' route choice. Meanwhile, due to the limited cruising range, EV drivers need to better learn about the required energy for the whole trip to make decisions about whether charging or not and where to charge (i.e., charging reliability). Since EV energy consumption is highly related to travel speed, network uncertainty affects travel time and charging demand estimation significantly. Considering the network uncertainty resulted from link degradation, which influences the distribution of travel demand on transportation network and the energy demand on power network, this paper aims to develop a reliability-based network equilibrium framework for accommodating degradable road conditions with the addition of EVs. First, based on the link travel time distribution, the mean and variance of route travel time and monetary expenses related to energy consumption are deduced, respectively. And the charging time distribution of EVs with charging demand is also estimated. Then, a nested structure is considered to deal with the difference of route choice behavior derived by the different uncertainty degrees between the routes with and without degradable links. Given the expected generalized travel cost and a psychological safety margin, a traffic assignment model with the addition of EVs is formulated. Subsequently, a heuristic solution algorithm is developed to solve the proposed model. Finally, the effects of travelers' risk attitude, network degradation degree, and EV penetration rate on network performance are illustrated through an example network. The numerical results show that the difference of travelers' risk attitudes does have impact on the route choice, and the widespread adoption of EVs can cut down the total system travel cost effectively when the transportation network is more reliable.

Energy and time modelling of kerbside waste collection: Changes incurred when adding source separated food waste.

PubMed

Edwards, Joel; Othman, Maazuza; Burn, Stewart; Crossin, Enda

2016-10-01

The collection of source separated kerbside municipal FW (SSFW) is being incentivised in Australia, however such a collection is likely to increase the fuel and time a collection truck fleet requires. Therefore, waste managers need to determine whether the incentives outweigh the cost. With literature scarcely describing the magnitude of increase, and local parameters playing a crucial role in accurately modelling kerbside collection; this paper develops a new general mathematical model that predicts the energy and time requirements of a collection regime whilst incorporating the unique variables of different jurisdictions. The model, Municipal solid waste collect (MSW-Collect), is validated and shown to be more accurate at predicting fuel consumption and trucks required than other common collection models. When predicting changes incurred for five different SSFW collection scenarios, results show that SSFW scenarios require an increase in fuel ranging from 1.38% to 57.59%. There is also a need for additional trucks across most SSFW scenarios tested. All SSFW scenarios are ranked and analysed in regards to fuel consumption; sensitivity analysis is conducted to test key assumptions. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Extracellular space preservation aids the connectomic analysis of neural circuits.

PubMed

Pallotto, Marta; Watkins, Paul V; Fubara, Boma; Singer, Joshua H; Briggman, Kevin L

2015-12-09

Dense connectomic mapping of neuronal circuits is limited by the time and effort required to analyze 3D electron microscopy (EM) datasets. Algorithms designed to automate image segmentation suffer from substantial error rates and require significant manual error correction. Any improvement in segmentation error rates would therefore directly reduce the time required to analyze 3D EM data. We explored preserving extracellular space (ECS) during chemical tissue fixation to improve the ability to segment neurites and to identify synaptic contacts. ECS preserved tissue is easier to segment using machine learning algorithms, leading to significantly reduced error rates. In addition, we observed that electrical synapses are readily identified in ECS preserved tissue. Finally, we determined that antibodies penetrate deep into ECS preserved tissue with only minimal permeabilization, thereby enabling correlated light microscopy (LM) and EM studies. We conclude that preservation of ECS benefits multiple aspects of the connectomic analysis of neural circuits.

77 FR 29935 - 2012 Technical Corrections, Clarifying and Other Amendments to the Greenhouse Gas Reporting Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

...The EPA is proposing to amend specific provisions of the Greenhouse Gas Reporting Rule to provide greater clarity and flexibility to facilities subject to reporting emissions from certain source categories. These source categories will report greenhouse gas (GHG) data for the first time in September of 2012. The proposed changes are not expected to significantly change the overall calculation and monitoring requirements of the Greenhouse Gas Reporting Rule or add additional requirements for reporters, but are expected to correct errors and clarify existing requirements in order to facilitate accurate and timely reporting. The EPA is also proposing confidentiality determinations for four new data elements for the fluorinated gas production source category of the Greenhouse Gas Reporting Rule. Lastly, we are proposing an amendment to Table A-7 of the general provisions to add a data element used as an input to an emission equation in the fluorinated gas production source category.

Study of V/STOL aircraft implementation. Volume 1: Summary

NASA Technical Reports Server (NTRS)

Portenier, W. J.; Webb, H. M.

1973-01-01

A high density short haul air market which by 1980 is large enough to support the introduction of an independent short haul air transportation system is discussed. This system will complement the existing air transportation system and will provide relief of noise and congestion problems at conventional airports. The study has found that new aircraft, exploiting V/STOL and quiet engine technology, can be available for implementing these new services, and they can operate from existing reliever and general aviation airports. The study has also found that the major funding requirements for implementing new short haul services could be borne by private capital, and that the government funding requirement would be minimal and/or recovered through the airline ticket tax. In addition, a suitable new short haul aircraft would have a market potential for $3.5 billion in foreign sales. The long lead times needed for aircraft and engine technology development will require timely actions by federal agencies.

A 'digital' technique for manual extraction of data from aerial photography

NASA Technical Reports Server (NTRS)

Istvan, L. B.; Bondy, M. T.

1977-01-01

The interpretation procedure described uses a grid cell approach. In addition, a random point is located in each cell. The procedure required that the cell/point grid be established on a base map, and identical grids be made to precisely match the scale of the photographic frames. The grid is then positioned on the photography by visual alignment to obvious features. Several alignments on one frame are sometimes required to make a precise match of all points to be interpreted. This system inherently corrects for distortions in the photography. Interpretation is then done cell by cell. In order to meet the time constraints, first order interpretation should be maintained. The data is put onto coding forms, along with other appropriate data, if desired. This 'digital' manual interpretation technique has proven to be efficient, and time and cost effective, while meeting strict requirements for data format and accuracy.

Integrated Medical Model (IMM) 4.0 Enhanced Functionalities

NASA Technical Reports Server (NTRS)

Young, M.; Keenan, A. B.; Saile, L.; Boley, L. A.; Walton, M. E.; Shah, R. V.; Kerstman, E. L.; Myers, J. G.

2015-01-01

The Integrated Medical Model is a probabilistic simulation model that uses input data on 100 medical conditions to simulate expected medical events, the resources required to treat, and the resulting impact to the mission for specific crew and mission characteristics. The newest development version of IMM, IMM v4.0, adds capabilities that remove some of the conservative assumptions that underlie the current operational version, IMM v3. While IMM v3 provides the framework to simulate whether a medical event occurred, IMMv4 also simulates when the event occurred during a mission timeline. This allows for more accurate estimation of mission time lost and resource utilization. In addition to the mission timeline, IMMv4.0 features two enhancements that address IMM v3 assumptions regarding medical event treatment. Medical events in IMMv3 are assigned the untreated outcome if any resource required to treat the event was unavailable. IMMv4 allows for partially treated outcomes that are proportional to the amount of required resources available, thus removing the dichotomous treatment assumption. An additional capability IMMv4 is to use an alternative medical resource when the primary resource assigned to the condition is depleted, more accurately reflecting the real-world system. The additional capabilities defining IMM v4.0the mission timeline, partial treatment, and alternate drug result in more realistic predicted mission outcomes. The primary model outcomes of IMM v4.0 for the ISS6 mission, including mission time lost, probability of evacuation, and probability of loss of crew life, are be compared to those produced by the current operational version of IMM to showcase enhanced prediction capabilities.

Automated Flight Dynamics Product Generation for the EOS AM-1 Spacecraft

NASA Technical Reports Server (NTRS)

Matusow, Carla

1999-01-01

As part of NASA's Earth Science Enterprise, the Earth Observing System (EOS) AM-1 spacecraft is designed to monitor long-term, global, environmental changes. Because of the complexity of the AM-1 spacecraft, the mission operations center requires more than 80 distinct flight dynamics products (reports). To create these products, the AM-1 Flight Dynamics Team (FDT) will use a combination of modified commercial software packages (e.g., Analytical Graphic's Satellite ToolKit) and NASA-developed software applications. While providing the most cost-effective solution to meeting the mission requirements, the integration of these software applications raises several operational concerns: (1) Routine product generation requires knowledge of multiple applications executing on variety of hardware platforms. (2) Generating products is a highly interactive process requiring a user to interact with each application multiple times to generate each product. (3) Routine product generation requires several hours to complete. (4) User interaction with each application introduces the potential for errors, since users are required to manually enter filenames and input parameters as well as run applications in the correct sequence. Generating products requires some level of flight dynamics expertise to determine the appropriate inputs and sequencing. To address these issues, the FDT developed an automation software tool called AutoProducts, which runs on a single hardware platform and provides all necessary coordination and communication among the various flight dynamics software applications. AutoProducts, autonomously retrieves necessary files, sequences and executes applications with correct input parameters, and deliver the final flight dynamics products to the appropriate customers. Although AutoProducts will normally generate pre-programmed sets of routine products, its graphical interface allows for easy configuration of customized and one-of-a-kind products. Additionally, AutoProducts has been designed as a mission-independent tool, and can be easily reconfigured to support other missions or incorporate new flight dynamics software packages. After the AM-1 launch, AutoProducts will run automatically at pre-determined time intervals . The AutoProducts tool reduces many of the concerns associated with the flight dynamics product generation. Although AutoProducts required a significant effort to develop because of the complexity of the interfaces involved, its use will provide significant cost savings through reduced operator time and maximum product reliability. In addition, user satisfaction is significantly improved and flight dynamics experts have more time to perform valuable analysis work. This paper will describe the evolution of the AutoProducts tool, highlighting the cost savings and customer satisfaction resulting from its development. It will also provide details about the tool including its graphical interface and operational capabilities.

10 CFR 20.2302 - Additional requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Additional requirements. 20.2302 Section 20.2302 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Exemptions and Additional Requirements § 20.2302 Additional requirements. The Commission may, by rule, regulation, or order, impose...

10 CFR 20.2302 - Additional requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Additional requirements. 20.2302 Section 20.2302 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Exemptions and Additional Requirements § 20.2302 Additional requirements. The Commission may, by rule, regulation, or order, impose...

10 CFR 20.2302 - Additional requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Additional requirements. 20.2302 Section 20.2302 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Exemptions and Additional Requirements § 20.2302 Additional requirements. The Commission may, by rule, regulation, or order, impose...

Just-in-time Design and Additive Manufacture of Patient-specific Medical Implants

NASA Astrophysics Data System (ADS)

Shidid, Darpan; Leary, Martin; Choong, Peter; Brandt, Milan

Recent advances in medical imaging and manufacturing science have enabled the design and production of complex, patient-specific orthopaedic implants. Additive Manufacture (AM) generates three-dimensional structures layer by layer, and is not subject to the constraints associated with traditional manufacturing methods. AM provides significant opportunities for the design of novel geometries and complex lattice structures with enhanced functional performance. However, the design and manufacture of patient-specific AM implant structures requires unique expertise in handling various optimization platforms. Furthermore, the design process for complex structures is computationally intensive. The primary aim of this research is to enable the just-in-time customisation of AM prosthesis; whereby AM implant design and manufacture be completed within the time constraints of a single surgical procedure, while minimising prosthesis mass and optimising the lattice structure to match the stiffness of the surrounding bone tissue. In this research, a design approach using raw CT scan data is applied to the AM manufacture of femoral prosthesis. Using the proposed just-in-time concept, the mass of the prosthesis was rapidly designed and manufactured while satisfying the associated structural requirements. Compressive testing of lattice structures manufactured using proposed method shows that the load carrying capacity of the resected composite bone can be recovered by up to 85% and the compressive stiffness of the AM prosthesis is statistically indistinguishable from the stiffness of the initial bone.

Adaptation of the Carter-Tracy water influx calculation to groundwater flow simulation

USGS Publications Warehouse

Kipp, Kenneth L.

1986-01-01

The Carter-Tracy calculation for water influx is adapted to groundwater flow simulation with additional clarifying explanation not present in the original papers. The Van Everdingen and Hurst aquifer-influence functions for radial flow from an outer aquifer region are employed. This technique, based on convolution of unit-step response functions, offers a simple but approximate method for embedding an inner region of groundwater flow simulation within a much larger aquifer region where flow can be treated in an approximate fashion. The use of aquifer-influence functions in groundwater flow modeling reduces the size of the computational grid with a corresponding reduction in computer storage and execution time. The Carter-Tracy approximation to the convolution integral enables the aquifer influence function calculation to be made with an additional storage requirement of only two times the number of boundary nodes more than that required for the inner region simulation. It is a good approximation for constant flow rates but is poor for time-varying flow rates where the variation is large relative to the mean. A variety of outer aquifer region geometries, exterior boundary conditions, and flow rate versus potentiometric head relations can be used. The radial, transient-flow case presented is representative. An analytical approximation to the functions of Van Everdingen and Hurst for the dimensionless potentiometric head versus dimensionless time is given.

13 CFR 127.504 - What additional requirements must a concern satisfy to submit an offer on an EDWOSB or WOSB...

Code of Federal Regulations, 2014 CFR

2014-01-01

... certifications in SAM (or any successor system) are accurate and complete at the time it submits its offer to the... corresponding to the NAICS code assigned to the contract; (2) It is listed in SAM (or any successor system) as...

Species Profiles. Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (Gulf of Mexico). GRASS SHRIMP.

DTIC Science & Technology

1985-03-01

8 Salinity .................................................... 8 Brackish-Water shrimp...names ........ Palaemonetes Order ..................... Decapoda p!. ; P. vulgaris; P. intermedius; Family ................. Palaemonidae P.paludosus...Spawning may produce an additional brood, depending on the species or time of The spawning season of grass spawning (Broad and Hubschman 1963; shrimp

EvoBuild: A Quickstart Toolkit for Programming Agent-Based Models of Evolutionary Processes

ERIC Educational Resources Information Center

Wagh, Aditi; Wilensky, Uri

2018-01-01

Extensive research has shown that one of the benefits of programming to learn about scientific phenomena is that it facilitates learning about mechanisms underlying the phenomenon. However, using programming activities in classrooms is associated with costs such as requiring additional time to learn to program or students needing prior experience…

76 FR 79141 - List of Rules To Be Reviewed Pursuant to the Regulatory Flexibility Act

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... initial notice within a reasonable time after establishing a customer relationship in two additional..., requires an agency to review its rules that have a significant economic impact upon a substantial number of... be amended or rescinded * * * to minimize any significant economic impact of the rules upon a...

Water Quality in the Production of Containerized Longleaf Pine Seedlings

Treesearch

David J. Moorhead; John M. Ruter

2002-01-01

The consistent production of quality container grown seedlings requires that key production variables be identified and controlled; otherwise, quality and the percentage of marketable plants will be erratic (Garber and Ruter 1993a). Additionally, production times and costs may increase unless production variables are monitored and managed throughout the production...

78 FR 8273 - Approval of Air Quality Implementation Plans; Navajo Nation; Regional Haze Requirements for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

... in significant visibility improvement that is well-balanced with the cost of those controls. For a... visibility benefits over time and that there may be changes in energy demand, supply or other developments... encourages a robust public discussion of our proposed BART determination and alternative, the additional...

"Counting" Serially Presented Stimuli by Human and Nonhuman Primates and Pigeons

ERIC Educational Resources Information Center

Roberts, William A.

2010-01-01

Much of Stewart Hulse's career was spent analyzing how animals can extract patterned information from sequences of stimuli. Yet an additional form of information contained in a sequence may be the number of times different elements occurred. Experiments that required numerical discrimination between different stimulus items presented in sequence…

7 CFR Appendix A to Subpart B of... - Review Rating Summary, RUS Form 300

Code of Federal Regulations, 2012 CFR

2012-01-01

...—ENGINEERING 11. System Load Conditions and Losses a. Annual System Loses, ____%—Rating:____ b. Annual Load..., RUS Form 300 Borrower Designation ____ Date Prepared ____ Ratings on form are: 0: Unsatisfactory—no... recommendations 3: Satisfactory—no additional action required at this time N/A: Not applicable PART I—TRANSMISSION...

7 CFR Appendix A to Subpart B of... - Review Rating Summary, RUS Form 300

Code of Federal Regulations, 2013 CFR

2013-01-01

...—ENGINEERING 11. System Load Conditions and Losses a. Annual System Loses, ____%—Rating:____ b. Annual Load..., RUS Form 300 Borrower Designation ____ Date Prepared ____ Ratings on form are: 0: Unsatisfactory—no... recommendations 3: Satisfactory—no additional action required at this time N/A: Not applicable PART I—TRANSMISSION...

7 CFR Appendix A to Subpart B of... - Review Rating Summary, RUS Form 300

Code of Federal Regulations, 2010 CFR

2010-01-01

...—ENGINEERING 11. System Load Conditions and Losses a. Annual System Loses, ____%—Rating:____ b. Annual Load..., RUS Form 300 Borrower Designation ____ Date Prepared ____ Ratings on form are: 0: Unsatisfactory—no... recommendations 3: Satisfactory—no additional action required at this time N/A: Not applicable PART I—TRANSMISSION...

7 CFR Appendix A to Subpart B of... - Review Rating Summary, RUS Form 300

Code of Federal Regulations, 2011 CFR

2011-01-01

...—ENGINEERING 11. System Load Conditions and Losses a. Annual System Loses, ____%—Rating:____ b. Annual Load..., RUS Form 300 Borrower Designation ____ Date Prepared ____ Ratings on form are: 0: Unsatisfactory—no... recommendations 3: Satisfactory—no additional action required at this time N/A: Not applicable PART I—TRANSMISSION...

76 FR 52862 - Time for Payment of Certain Excise Taxes, and Quarterly Excise Tax Payments for Small Alcohol...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-24

... 40 Cigars and cigarettes, Claims, Electronic fund transfers, Excise taxes, Labeling, Packaging and... that are not required to pay taxes through electronic funds transfer (EFT), this first payment period..., Electronic funds transfers, Excise taxes, Exports, Food additives, Fruit juices, Labeling, Liquors, Packaging...

34 CFR 650.33 - What is the duration of a fellowship?

Code of Federal Regulations, 2011 CFR

2011-07-01

... for a doctoral degree program of study for a total of 48 months or the time required for receiving the... application and that the fellow has attained satisfactory progress in the fellow's academic studies; and (iii) A recommendation from the institution that the additional period of fellowship support for...

34 CFR 650.33 - What is the duration of a fellowship?

Code of Federal Regulations, 2010 CFR

2010-07-01

... for a doctoral degree program of study for a total of 48 months or the time required for receiving the... application and that the fellow has attained satisfactory progress in the fellow's academic studies; and (iii) A recommendation from the institution that the additional period of fellowship support for...

14 CFR Appendix P to Part 121 - Requirements for ETOPS and Polar Operations

Code of Federal Regulations, 2013 CFR

2013-01-01

... the airplane's time-limited systems may not be less than 138 minutes calculated in accordance with... addition to the equipment specified in the certificate holder's MEL for 180-minute ETOPS, the following... electrical and pneumatic supply and operating to the APU's designed capability). (iii) The auto throttle...

14 CFR Appendix P to Part 121 - Requirements for ETOPS and Polar Operations

Code of Federal Regulations, 2014 CFR

2014-01-01

... the airplane's time-limited systems may not be less than 138 minutes calculated in accordance with... addition to the equipment specified in the certificate holder's MEL for 180-minute ETOPS, the following... electrical and pneumatic supply and operating to the APU's designed capability). (iii) The auto throttle...

14 CFR Appendix P to Part 121 - Requirements for ETOPS and Polar Operations

Code of Federal Regulations, 2012 CFR

2012-01-01

... the airplane's time-limited systems may not be less than 138 minutes calculated in accordance with... addition to the equipment specified in the certificate holder's MEL for 180-minute ETOPS, the following... electrical and pneumatic supply and operating to the APU's designed capability). (iii) The auto throttle...

14 CFR Appendix P to Part 121 - Requirements for ETOPS and Polar Operations

Code of Federal Regulations, 2011 CFR

2011-01-01

... the airplane's time-limited systems may not be less than 138 minutes calculated in accordance with... addition to the equipment specified in the certificate holder's MEL for 180-minute ETOPS, the following... electrical and pneumatic supply and operating to the APU's designed capability). (iii) The auto throttle...

14 CFR Appendix P to Part 121 - Requirements for ETOPS and Polar Operations

Code of Federal Regulations, 2010 CFR

2010-01-01

... the airplane's time-limited systems may not be less than 138 minutes calculated in accordance with... addition to the equipment specified in the certificate holder's MEL for 180-minute ETOPS, the following... electrical and pneumatic supply and operating to the APU's designed capability). (iii) The auto throttle...

The New Literacies of Online Reading Comprehension: Expanding the Literacy and Learning Curriculum

ERIC Educational Resources Information Center

Leu, Donald J.; McVerry, J. Gregory; O'Byrne, W. Ian; Kiili, Carita; Zawilinski, Lisa; Everett-Cacopardo, Heidi; Kennedy, Clint; Forzani, Elena

2011-01-01

This commentary explores a central issue for our times, online reading comprehension. It first defines three issues that have largely gone unnoticed as the Internet enters our classrooms: (1) literacy has become deictic; (2) effective online information use requires additional online reading comprehension practices, skills, and dispositions; and…

76 FR 28383 - Occupational Injury and Illness Recording and Reporting Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-17

...., involves days away from work, restricted work, or medical treatment beyond first aid). The only additional... establishment the first year and 67 cents in future years). The costs represent the time that establishments would need to become familiar with the rule (5 minutes per establishment the first year) and to...

78 FR 33193 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

.... In addition, BMS 8-39 fire retardant properties, which deteriorate over time, can provide a fuel... flight deck and cargo compartments), with seals made of BMS 8-39 urethane foam, a material with fire-retardant properties that deteriorate with age. This AD requires replacing certain seals made of BMS 8-39...

30 CFR 250.434 - What are the recordkeeping requirements for diverter actuations and tests?

Code of Federal Regulations, 2010 CFR

2010-07-01

... diverter actuations and tests? 250.434 Section 250.434 Mineral Resources MINERALS MANAGEMENT SERVICE... for diverter actuations and tests? You must record the time, date, and results of all diverter actuations and tests in the driller's report. In addition, you must: (a) Record the diverter pressure test on...

A high-current rail-type gas switch with preionization by an additional corona discharge

NASA Astrophysics Data System (ADS)

Antipov, E. I.; Belozerov, O. S.; Krastelev, E. G.

2016-12-01

The characteristics of a high-current rail-type gas switch with preionization of the gas (air) in a spark gap by an additional corona discharge are investigated. The experiments were performed in a voltage range of 10-45 kV using a two-electrode switch consisting of two cylindrical electrodes with a diameter of 22 mm and a length of 100 mm and a set of laterally located corona-discharge needles. The requirements for the position and size of the needles are defined for which a corona discharge is ignited before a breakdown of the main gap and does not change to a sparking form, and the entire length of the rail electrodes is efficiently used. The fulfillment of these requirements ensures stable operation of the switch with a small variation of the pulse breakdown voltage, which is not more than 1% for a fixed voltage-pulse rise time in the range from 150 ns to 3.5 μs. A short delay time of the switch breakdown makes it possible to control the two-electrode switch by an overvoltage pulse of nanosecond duration.

On the age of the Nele asteroid family

NASA Astrophysics Data System (ADS)

Carruba, V.; Vokrouhlický, D.; Nesvorný, D.; Aljbaae, S.

2018-06-01

The Nele group, formerly known as the Iannini family, is one of the youngest asteroid families in the main belt. Previously, it has been noted that the pericentre longitudes ϖ and nodal longitudes Ω of its largest member asteroids are clustered at the present time, therefore suggesting that the collisional break-up of parent body must have happened recently. Here, we verify this conclusion by detailed orbit-propagation of a synthetic Nele family and show that the current level of clustering of secular angles of the largest Nele family members requires an approximate age limit of 4.5 Myr. Additionally, we make use of an updated and largely extended Nele membership to obtain, for the first time, an age estimate of this family using the backward integration method. Convergence of the secular angles in a purely gravitational model and in a model including the non-gravitational forces caused by the Yarkovsky effect are both compatible with an age younger than 7 Myr. More accurate determination of the Nele family age would require additional data about the spin state of its members.

Stability of human sera collected for clinical chemistry determinations

NASA Technical Reports Server (NTRS)

Townsend, F. M.

1969-01-01

Problems in collecting and shipping human sera for clinical chemical analyses affect their stability and require proper preservation methods. It is shown that glutamic pyruvate transaminase is very unstable and serum cannot be shipped unless the shipping time is carefully controlled and is less than two days under refrigeration. A limit of four days handling time and avoidance of light exposure are required in bilirubin testing of specimens. Addition of 11 mg of a 10 to 1 mixture of finely powdered sodium fluoride and thymol per ml of blood to preserve specimen stability en route to a central laboratory prevents glycolysis. A citrate buffer at pH 6.2 in serum to be tested for alkaline phosphatase lessens decline at room temperature.

Water tribology on graphene.

PubMed

N'guessan, Hartmann E; Leh, Aisha; Cox, Paris; Bahadur, Prashant; Tadmor, Rafael; Patra, Prabir; Vajtai, Robert; Ajayan, Pulickel M; Wasnik, Priyanka

2012-01-01

Classical experiments show that the force required to slide liquid drops on surfaces increases with the resting time of the drop, t(rest), and reaches a plateau typically after several minutes. Here we use the centrifugal adhesion balance to show that the lateral force required to slide a water drop on a graphene surface is practically invariant with t(rest). In addition, the drop's three-phase contact line adopts a peculiar micrometric serrated form. These observations agree well with current theories that relate the time effect to deformation and molecular re-orientation of the substrate surface. Such molecular re-orientation is non-existent on graphene, which is chemically homogenous. Hence, graphene appears to provide a unique tribological surface test bed for a variety of liquid drop-surface interactions.

Parametric State Space Structuring

NASA Technical Reports Server (NTRS)

Ciardo, Gianfranco; Tilgner, Marco

1997-01-01

Structured approaches based on Kronecker operators for the description and solution of the infinitesimal generator of a continuous-time Markov chains are receiving increasing interest. However, their main advantage, a substantial reduction in the memory requirements during the numerical solution, comes at a price. Methods based on the "potential state space" allocate a probability vector that might be much larger than actually needed. Methods based on the "actual state space", instead, have an additional logarithmic overhead. We present an approach that realizes the advantages of both methods with none of their disadvantages, by partitioning the local state spaces of each submodel. We apply our results to a model of software rendezvous, and show how they reduce memory requirements while, at the same time, improving the efficiency of the computation.

Process analysis of an in store production of knitted clothing

NASA Astrophysics Data System (ADS)

Buecher, D.; Kemper, M.; Schmenk, B.; Gloy, Y.-S.; Gries, T.

2017-10-01

In the textile and clothing industry, global value-added networks are widespread for textile and clothing production. As a result of global networking, the value chain is fragmented and a great deal of effort is required to coordinate the production processes [1]. In addition, the planning effort on the quantity and design of the goods is high and risky. Today the fashion industry is facing an increasing customer demand for individual and customizable products in addition to short delivery times [2]. These challenges are passed down to the textile and clothing industry decreasing batch sizes and production times. Conventional clothing production cannot fulfill those demands especially when combined with more and more individual or customizable designs. Hence new production concepts have to be developed.

Separating OR, SUM, and XOR Circuits☆

PubMed Central

Find, Magnus; Göös, Mika; Järvisalo, Matti; Kaski, Petteri; Koivisto, Mikko; Korhonen, Janne H.

2017-01-01

Given a boolean n × n matrix A we consider arithmetic circuits for computing the transformation x ↦ Ax over different semirings. Namely, we study three circuit models: monotone OR-circuits, monotone SUM-circuits (addition of non-negative integers), and non-monotone XOR-circuits (addition modulo 2). Our focus is on separating OR-circuits from the two other models in terms of circuit complexity: We show how to obtain matrices that admit OR-circuits of size O(n), but require SUM-circuits of size Ω(n3/2/log2n).We consider the task of rewriting a given OR-circuit as a XOR-circuit and prove that any subquadratic-time algorithm for this task violates the strong exponential time hypothesis. PMID:28529379

10 CFR 55.7 - Additional requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Additional requirements. 55.7 Section 55.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) OPERATORS' LICENSES General Provisions § 55.7 Additional requirements. The Commission may, by rule, regulation, or order, impose upon any licensee such requirements, in addition to...

10 CFR 55.7 - Additional requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Additional requirements. 55.7 Section 55.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) OPERATORS' LICENSES General Provisions § 55.7 Additional requirements. The Commission may, by rule, regulation, or order, impose upon any licensee such requirements, in addition to...

Convolutional code performance in planetary entry channels

NASA Technical Reports Server (NTRS)

Modestino, J. W.

1974-01-01

The planetary entry channel is modeled for communication purposes representing turbulent atmospheric scattering effects. The performance of short and long constraint length convolutional codes is investigated in conjunction with coherent BPSK modulation and Viterbi maximum likelihood decoding. Algorithms for sequential decoding are studied in terms of computation and/or storage requirements as a function of the fading channel parameters. The performance of the coded coherent BPSK system is compared with the coded incoherent MFSK system. Results indicate that: some degree of interleaving is required to combat time correlated fading of channel; only modest amounts of interleaving are required to approach performance of memoryless channel; additional propagational results are required on the phase perturbation process; and the incoherent MFSK system is superior when phase tracking errors are considered.

Orbital transfer vehicle launch operations study. Volume 2: Detailed summary

NASA Technical Reports Server (NTRS)

1986-01-01

A series of Operational Design Drivers were identified. Several of these could have significant impact(s) on program costs. These recommendations, for example, include such items as: complete factory assembly and checkout prior to shipment to the ground launch site to make significant reductions in time required at the launch site as well as overall manpower required to do this work; minimize use of nonstandard equipment when orbiter provided equipment is available; and require commonality (or interchangeability) of subsystem equipment elements that are common to the space station, Orbit Maneuvering Vehicles, and/or Orbit Transfer Vehicles. Several additional items were identified that will require a significant amount of management attention (and direction) to resolve. Key elements of the space based processing plans are discussed.

Field validation of protocols developed to evaluate in-line mastitis detection systems.

PubMed

Kamphuis, C; Dela Rue, B T; Eastwood, C R

2016-02-01

This paper reports on a field validation of previously developed protocols for evaluating the performance of in-line mastitis-detection systems. The protocols outlined 2 requirements of these systems: (1) to detect cows with clinical mastitis (CM) promptly and accurately to enable timely and appropriate treatment and (2) to identify cows with high somatic cell count (SCC) to manage bulk milk SCC levels. Gold standard measures, evaluation tests, performance measures, and performance targets were proposed. The current study validated the protocols on commercial dairy farms with automated in-line mastitis-detection systems using both electrical conductivity (EC) and SCC sensor systems that both monitor at whole-udder level. The protocol for requirement 1 was applied on 3 commercial farms. For requirement 2, the protocol was applied on 6 farms; 3 of them had low bulk milk SCC (128×10(3) cells/mL) and were the same farms as used for field evaluation of requirement 1. Three farms with high bulk milk SCC (270×10(3) cells/mL) were additionally enrolled. The field evaluation methodology and results were presented at a workshop including representation from 7 international suppliers of in-line mastitis-detection systems. Feedback was sought on the acceptance of standardized performance evaluation protocols and recommended refinements to the protocols. Although the methodology for requirement 1 was relatively labor intensive and required organizational skills over an extended period, no major issues were encountered during the field validation of both protocols. The validation, thus, proved the protocols to be practical. Also, no changes to the data collection process were recommended by the technology supplier representatives. However, 4 recommendations were made to refine the protocols: inclusion of an additional analysis that ignores small (low-density) clot observations in the definition of CM, extension of the time window from 4 to 5 milkings for timely alerts for CM, setting a maximum number of 10 milkings for the time window to detect a CM episode, and presentation of sensitivity for a larger range of false alerts per 1,000 milkings replacing minimum performance targets. The recommended refinements are discussed with suggested changes to the original protocols. The information presented is intended to inform further debate toward achieving international agreement on standard protocols to evaluate performance of in-line mastitis-detection systems. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

High pulmonary vascular resistance in addition to low right ventricular stroke work index effectively predicts biventricular assist device requirement.

PubMed

Imamura, Teruhiko; Kinugawa, Koichiro; Kinoshita, Osamu; Nawata, Kan; Ono, Minoru

2016-03-01

Although the right ventricular stroke work index (RVSWI) is a good index for RV function, a low RVSWI is not necessarily an indicator for the need for a right ventricular assist device at the time of left VAD implantation. We here aimed to determine a more precise indicator for the need for a biventricular assist device (BiVAD). In total, 116 patients (mean age, 38 ± 14 years), who underwent hemodynamic assessments preoperatively including 12 BiVAD patients, and had been followed at our institute from 2003 to 2015, were included. Multivariate logistic regression analysis indicated that RVSWI and pulmonary vascular resistance (PVR) were independent predictors of BiVAD requirement (P < 0.05 for both). In addition, all patients were classified into 4 groups: (1) normal (RVSWI > 5 g/m, PVR < 3.7 WU), (2) pulmonary hypertension (RVSWI > 5, PVR > 3.7), (3) RV failure (RVSWI < 5, PVR < 3.7), and (4) both pulmonary hypertension and RV failure (RVSWI < 5, PVR > 3.7), and examined. Most of the patients in Group 4 (75 %), with acutely depressed hemodynamics and inflammatory responses in the myocardium, required BiVAD. Overall, patients with BiVAD had a worse survival rate as compared with those with LVAD alone. In conclusion, high PVR in addition to low RVSWI effectively predicts BiVAD requirement.

Field Application of a Rapid Spectrophotometric Method for Determination of Persulfate in Soil

PubMed Central

Cunningham, Colin J.; Pitschi, Vanessa; Anderson, Peter; Barry, D. A.; Patterson, Colin; Peshkur, Tanya A.

2013-01-01

Remediation of hydrocarbon contaminated soils can be performed both in situ and ex situ using chemical oxidants such as sodium persulfate. Standard methods for quantifying persulfate require either centrifugation or prolonged settling times. An optimized soil extraction procedure was developed for persulfate involving simple water extraction using a modified disposable syringe. This allows considerable saving of time and removes the need for centrifugation. The extraction time was reduced to only 5 min compared to 15 min for the standard approach. A comparison of the two approaches demonstrated that each provides comparable results. Comparisons were made using high (93 g kg−1 soil) and low (9.3 g kg−1 soil) additions of sodium persulfate to a petroleum hydrocarbon-contaminated soil, as well as sand spiked with diesel. Recoveries of 95±1% and 96±10% were observed with the higher application rate in the contaminated soil and spiked sand, respectively. Corresponding recoveries of 86±5% and 117±19% were measured for the lower application rate. Results were obtained in only 25 min and the method is well suited to batch analyses. In addition, it is suitable for application in a small field laboratory or even a mobile, vehicle-based system, as it requires minimal equipment and reagents. PMID:23776446

Programming and reprogramming sequence timing following high and low contextual interference practice.

PubMed

Wright, David L; Magnuson, Curt E; Black, Charles B

2005-09-01

Individuals practiced two unique discrete sequence production tasks that differed in their relative time profile in either a blocked or random practice schedule. Each participant was subsequently administered a "precuing" protocol to examine the cost of initially compiling or modifying the plan for an upcoming movement's relative timing. The findings indicated that, in general, random practice facilitated the programming of the required movement timing, and this was accomplished while exhibiting greater accuracy in movement production. Participants exposed to random practice exhibited the greatest motor programming benefit, when a modification to an already prepared movement timing profile was required. When movement timing was only partially constructed prior to the imperative signal, the individuals who were trained in blocked and random practice formats accrued a similar cost to complete the programming process. These data provide additional support for the recent claim of Immink & Wright (2001) that at least some of the benefit from experience in a random as opposed to blocked training context can be localized to superior development and implementation of the motor programming process before executing the movement.

Development of a real-time microchip PCR system for portable plant disease diagnosis.

PubMed

Koo, Chiwan; Malapi-Wight, Martha; Kim, Hyun Soo; Cifci, Osman S; Vaughn-Diaz, Vanessa L; Ma, Bo; Kim, Sungman; Abdel-Raziq, Haron; Ong, Kevin; Jo, Young-Ki; Gross, Dennis C; Shim, Won-Bo; Han, Arum

2013-01-01

Rapid and accurate detection of plant pathogens in the field is crucial to prevent the proliferation of infected crops. Polymerase chain reaction (PCR) process is the most reliable and accepted method for plant pathogen diagnosis, however current conventional PCR machines are not portable and require additional post-processing steps to detect the amplified DNA (amplicon) of pathogens. Real-time PCR can directly quantify the amplicon during the DNA amplification without the need for post processing, thus more suitable for field operations, however still takes time and require large instruments that are costly and not portable. Microchip PCR systems have emerged in the past decade to miniaturize conventional PCR systems and to reduce operation time and cost. Real-time microchip PCR systems have also emerged, but unfortunately all reported portable real-time microchip PCR systems require various auxiliary instruments. Here we present a stand-alone real-time microchip PCR system composed of a PCR reaction chamber microchip with integrated thin-film heater, a compact fluorescence detector to detect amplified DNA, a microcontroller to control the entire thermocycling operation with data acquisition capability, and a battery. The entire system is 25 × 16 × 8 cm(3) in size and 843 g in weight. The disposable microchip requires only 8-µl sample volume and a single PCR run consumes 110 mAh of power. A DNA extraction protocol, notably without the use of liquid nitrogen, chemicals, and other large lab equipment, was developed for field operations. The developed real-time microchip PCR system and the DNA extraction protocol were used to successfully detect six different fungal and bacterial plant pathogens with 100% success rate to a detection limit of 5 ng/8 µl sample.

Development of a Real-Time Microchip PCR System for Portable Plant Disease Diagnosis

PubMed Central

Kim, Hyun Soo; Cifci, Osman S.; Vaughn-Diaz, Vanessa L.; Ma, Bo; Kim, Sungman; Abdel-Raziq, Haron; Ong, Kevin; Jo, Young-Ki; Gross, Dennis C.; Shim, Won-Bo; Han, Arum

2013-01-01

Rapid and accurate detection of plant pathogens in the field is crucial to prevent the proliferation of infected crops. Polymerase chain reaction (PCR) process is the most reliable and accepted method for plant pathogen diagnosis, however current conventional PCR machines are not portable and require additional post-processing steps to detect the amplified DNA (amplicon) of pathogens. Real-time PCR can directly quantify the amplicon during the DNA amplification without the need for post processing, thus more suitable for field operations, however still takes time and require large instruments that are costly and not portable. Microchip PCR systems have emerged in the past decade to miniaturize conventional PCR systems and to reduce operation time and cost. Real-time microchip PCR systems have also emerged, but unfortunately all reported portable real-time microchip PCR systems require various auxiliary instruments. Here we present a stand-alone real-time microchip PCR system composed of a PCR reaction chamber microchip with integrated thin-film heater, a compact fluorescence detector to detect amplified DNA, a microcontroller to control the entire thermocycling operation with data acquisition capability, and a battery. The entire system is 25×16×8 cm3 in size and 843 g in weight. The disposable microchip requires only 8-µl sample volume and a single PCR run consumes 110 mAh of power. A DNA extraction protocol, notably without the use of liquid nitrogen, chemicals, and other large lab equipment, was developed for field operations. The developed real-time microchip PCR system and the DNA extraction protocol were used to successfully detect six different fungal and bacterial plant pathogens with 100% success rate to a detection limit of 5 ng/8 µl sample. PMID:24349341

Maintenance energy requirements of odor detection, explosive detection and human detection working dogs.

PubMed

Mullis, Rebecca A; Witzel, Angela L; Price, Joshua

2015-01-01

Despite their important role in security, little is known about the energy requirements of working dogs such as odor, explosive and human detection dogs. Previous researchers have evaluated the energy requirements of individual canine breeds as well as dogs in exercise roles such as sprint racing. This study is the first to evaluate the energy requirements of working dogs trained in odor, explosive and human detection. This retrospective study evaluated twenty adult dogs who maintained consistent body weights over a six month period. During this time, the average energy consumption was [Formula: see text] or two times the calculated resting energy requirement ([Formula: see text]). No statistical differences were found between breeds, age or sex, but a statistically significant association (p = 0.0033, R-square = 0.0854) was seen between the number of searches a dog performs and their energy requirement. Based on this study's population, it appears that working dogs have maintenance energy requirements similar to the 1974 National Research Council's (NRC) maintenance energy requirement of [Formula: see text] (National Research Council (NRC), 1974) and the [Formula: see text] reported for young laboratory beagles (Rainbird & Kienzle, 1990). Additional research is needed to determine if these data can be applied to all odor, explosive and human detection dogs and to determine if other types of working dogs (tracking, search and rescue etc.) have similar energy requirements.

Solution-Based 3D Printing of Polymers of Intrinsic Microporosity.

PubMed

Zhang, Fengyi; Ma, Yao; Liao, Jianshan; Breedveld, Victor; Lively, Ryan P

2018-05-28

Current additive manufacturing methods have significant limitations in the classes of compatible polymers. Many polymers of significant technological interest cannot currently be 3D printed. Here, a generalizable method for 3D printing of viscous tenary polymer solutions (polymer/solvent/nonsolvent) is applied to both "intrinsically porous" (a polymer of intrinsic microporosity, PIM-1) and "intrinsically nonporous" (cellulose acetate) polymers. Successful ternary ink formulations require balancing of solution thermodynamics (phase separation), mass transfer (solvent evaporation), and rheology. As a demonstration, a microporous polymer (PIM-1) incompatible with current additive manufacturing technologies is 3D printed into a high-efficiency mass transfer contactor exhibiting hierarchical porosity ranging from sub-nanometer to millimeter pores. Short contactors (1.27 cm) can fully purify (<1 ppm) toluene vapor (1000 ppm) in N 2 gas for 1.7 h, which is six times longer than PIM-1 in traditional structures, and more than 4000 times the residence time of gas in the contactor. This solution-based additive manufacturing approach greatly extends the range of 3D-printable materials. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Multi-trip vehicle routing and scheduling problem with time window in real life

NASA Astrophysics Data System (ADS)

Sze, San-Nah; Chiew, Kang-Leng; Sze, Jeeu-Fong

2012-09-01

This paper studies a manpower scheduling problem with multiple maintenance operations and vehicle routing considerations. Service teams located at a common service centre are required to travel to different customer sites. All customers must be served within given time window, which are known in advance. The scheduling process must take into consideration complex constraints such as a meal break during the team's shift, multiple travelling trips, synchronisation of service teams and working shifts. The main objective of this study is to develop a heuristic that can generate high quality solution in short time for large problem instances. A Two-stage Scheduling Heuristic is developed for different variants of the problem. Empirical results show that the proposed solution performs effectively and efficiently. In addition, our proposed approximation algorithm is very flexible and can be easily adapted to different scheduling environments and operational requirements.

Switching between simple cognitive tasks: the interaction of top-down and bottom-up factors

NASA Technical Reports Server (NTRS)

Ruthruff, E.; Remington, R. W.; Johnston, J. C.

2001-01-01

How do top-down factors (e.g., task expectancy) and bottom-up factors (e.g., task recency) interact to produce an overall level of task readiness? This question was addressed by factorially manipulating task expectancy and task repetition in a task-switching paradigm. The effects of expectancy and repetition on response time tended to interact underadditively, but only because the traditional binary task-repetition variable lumps together all switch trials, ignoring variation in task lag. When the task-recency variable was scaled continuously, all 4 experiments instead showed additivity between expectancy and recency. The results indicated that expectancy and recency influence different stages of mental processing. One specific possibility (the configuration-execution model) is that task expectancy affects the time required to configure upcoming central operations, whereas task recency affects the time required to actually execute those central operations.

Development of composite calibration standard for quantitative NDE by ultrasound and thermography

NASA Astrophysics Data System (ADS)

Dayal, Vinay; Benedict, Zach G.; Bhatnagar, Nishtha; Harper, Adam G.

2018-04-01

Inspection of aircraft components for damage utilizing ultrasonic Non-Destructive Evaluation (NDE) is a time intensive endeavor. Additional time spent during aircraft inspections translates to added cost to the company performing them, and as such, reducing this expenditure is of great importance. There is also great variance in the calibration samples from one entity to another due to a lack of a common calibration set. By characterizing damage types, we can condense the required calibration sets and reduce the time required to perform calibration while also providing procedures for the fabrication of these standard sets. We present here our effort to fabricate composite samples with known defects and quantify the size and location of defects, such as delaminations, and impact damage. Ultrasonic and Thermographic images are digitally enhanced to accurately measure the damage size. Ultrasonic NDE is compared with thermography.

Applications of magnetostrictive materials in the real-time monitoring of vehicle suspension components

NASA Astrophysics Data System (ADS)

Estrada, Raul

The purpose of this project is to explore applications of magnetostrictive materials for real-time monitoring of railroad suspension components, in particular bearings. Monitoring of such components typically requires the tracking of temperature vibration and load. In addition, real-time, long-term monitoring can be greatly facilitated through the use of wireless, self-powered sensors. Magnetostrictive materials, such as Terfenol-D, have the potential to address both requirements. Currently, piezoelectrics are used for many load and energy harvesting applications; however, they are fragile and are difficult to use for static load measurements. Magnetostrictive metals are tougher, and their property of variable permeability when stressed can be utilized to measure static loads. A prototype load sensor was successfully fabricated and characterized yielding less than 10% error under normal operating conditions. Energy harvesting experiments generated a little over 80 mW of power, which is sufficient to run low-power condition monitoring systems.

46 CFR 11.502 - Additional requirements for engineer endorsements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Additional requirements for engineer endorsements. 11... SEAMEN REQUIREMENTS FOR OFFICER ENDORSEMENTS Professional Requirements for Engineer Officer § 11.502 Additional requirements for engineer endorsements. (a) For all original and raise of grade of engineer...

46 CFR 11.502 - Additional requirements for engineer endorsements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Additional requirements for engineer endorsements. 11... SEAMEN REQUIREMENTS FOR OFFICER ENDORSEMENTS Professional Requirements for Engineer Officer § 11.502 Additional requirements for engineer endorsements. (a) For all original and raise of grade of engineer...

46 CFR 11.502 - Additional requirements for engineer endorsements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Additional requirements for engineer endorsements. 11... SEAMEN REQUIREMENTS FOR OFFICER ENDORSEMENTS Professional Requirements for Engineer Officer § 11.502 Additional requirements for engineer endorsements. (a) For all original and raise of grade of engineer...

46 CFR 11.502 - Additional requirements for engineer endorsements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Additional requirements for engineer endorsements. 11... SEAMEN REQUIREMENTS FOR OFFICER ENDORSEMENTS Professional Requirements for Engineer Officer § 11.502 Additional requirements for engineer endorsements. (a) For all original and raise of grade of engineer...

Bariatric surgery insurance requirements independently predict surgery dropout.

PubMed

Love, Kaitlin M; Mehaffey, J Hunter; Safavian, Dana; Schirmer, Bruce; Malin, Steven K; Hallowell, Peter T; Kirby, Jennifer L

2017-05-01

Many insurance companies have considerable prebariatric surgery requirements despite a lack of evidence for improved clinical outcomes. The hypothesis of this study is that insurance-specific requirements will be associated with a decreased progression to surgery and increased delay in time to surgery. Retrospective data collection was performed for patients undergoing bariatric surgery evaluation from 2010-2015. Patients who underwent surgery (SGY; n = 827; mean body mass index [BMI] 49.1) were compared with those who did not (no-SGY; n = 648; mean BMI: 49.4). Univariate and multivariate analysis were performed to identify specific co-morbidity and insurance specific predictors of surgical dropout and time to surgery. A total of 1475 patients using 12 major insurance payors were included. Univariate analysis found insurance requirements associated with surgical drop out included longer median diet duration (no-SGY = 6 mo; SGY = 3 mo; P<.001); primary care physician letter of necessity (P<.0001); laboratory testing (P = .019); and evaluation by cardiology (P<.001), pulmonology (P<.0001), or psychiatry (P = .0003). Using logistic regression to control for co-morbidities, longer diet requirement (odds ratio [OR] .88, P<.0001), primary care physician letter (OR .33, P<.0001), cardiology evaluation (OR .22, P = .038), and advanced laboratory testing (OR 5.75, P = .019) independently predicted surgery dropout. Additionally, surgical patients had an average interval between initial visit and surgery of 5.8±4.6 months with significant weight gain (2.1 kg, P<.0001). Many prebariatric surgery insurance requirements were associated with lack of patient progression to surgery in this study. In addition, delays in surgery were associated with preoperative weight gain. Although prospective and multicenter studies are needed, these findings have major policy implications suggesting insurance requirements may need to be reconsidered to improve medical care. Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Pathwise upper semi-continuity of random pullback attractors along the time axis

NASA Astrophysics Data System (ADS)

Cui, Hongyong; Kloeden, Peter E.; Wu, Fuke

2018-07-01

The pullback attractor of a non-autonomous random dynamical system is a time-indexed family of random sets, typically having the form {At(ṡ) } t ∈ R with each At(ṡ) a random set. This paper is concerned with the nature of such time-dependence. It is shown that the upper semi-continuity of the mapping t ↦At(ω) for each ω fixed has an equivalence relationship with the uniform compactness of the local union ∪s∈IAs(ω) , where I ⊂ R is compact. Applied to a semi-linear degenerate parabolic equation with additive noise and a wave equation with multiplicative noise we show that, in order to prove the above locally uniform compactness and upper semi-continuity, no additional conditions are required, in which sense the two properties appear to be general properties satisfied by a large number of real models.

Microlaparoscopic technique for partial salpingectomy using bipolar electrocoagulation.

PubMed

Siegle, J C; Cartmell, L W; Rayburn, W F

2001-07-01

To describe a technique of performing a partial salpingectomy using a small-diameter (2-mm) laparoscope and bipolar electrocoagulation. Sixty consecutive women desiring permanent sterilization underwent laparoscopic partial salpingectomy using a 2-mm transumbilical laparoscope and secondary midline sites suprapubically and midway above the pubis. A midportion of the tube was coagulated using Kleppinger forceps, transected with scissors and removed using grasping forceps. Additional time to remove both coagulated tubal segments averaged 4 minutes (range, 3-10). Each segment (mean, 1.5 cm; range, 0.9-2.4 cm) was confirmed in the operating room, then histologically. The transected tubal edges were separated with no thermal injury to nearby structures and with no mesosalpingeal hemorrhage. No cases required conversion from microlaparoscopy to a traditional method, and recovery time was not prolonged. The puncture sites healed well without sutures. Successful removal of electrocoagulated tubal segments with histologic confirmation was undertaken microlaparoscopically, with minimal additional operative time.

An Assessment of the IMEF Depot-Level Corrosion Prevention and Control Program and the Viability of Making it More Efficient and/or Outsourcing the Requirements through Private Sector Initiatives

DTIC Science & Technology

2002-12-01

as follows, with A being the simplest and C being the most inclusive: • Category A: Surface preparation, paint and undercoating; no bodywork . (This... bodywork due to the corrosion replacement or repair of corroded components such as door, battery boxes, or fenders with time of work not to exceed...8 hours. • Category C: Includes everything listed in category B in addition to some component disassembly required to treat corrosion. Bodywork

Characterization of quantum well structures using a photocathode electron microscope

NASA Technical Reports Server (NTRS)

Spencer, Michael G.; Scott, Craig J.

1989-01-01

Present day integrated circuits pose a challenge to conventional electronic and mechanical test methods. Feature sizes in the submicron and nanometric regime require radical approaches in order to facilitate electrical contact to circuits and devices being tested. In addition, microwave operating frequencies require careful attention to distributed effects when considering the electrical signal paths within and external to the device under test. An alternative testing approach which combines the best of electrical and optical time domain testing is presented, namely photocathode electron microscope quantitative voltage contrast (PEMQVC).

Potential of laser for SPS power transmission

NASA Technical Reports Server (NTRS)

Bain, C. N.

1978-01-01

Research on the feasibility of using a laser subsystem as an additional option for the transmission of the satellite power system (STS) power is presented. Current laser work and predictions for future laser performance provide a level of confidence that the development of a laser power transmission system is technologically feasible in the time frame required to develop the SBS. There are significant economic advantages in lower ground distribution costs and a reduction of more than two orders of magnitude in real estate requirements for ground based receiving/conversion sites.

Estimating net rainfall, evaporation and water storage of a bare soil from sequential L-band emissivities

NASA Technical Reports Server (NTRS)

Stroosnijder, L.; Lascano, R. J.; Newton, R. W.; Vanbavel, C. H. M.

1984-01-01

A general method to use a time series of L-band emissivities as an input to a hydrological model for continuously monitoring the net rainfall and evaporation as well as the water content over the entire soil profile is proposed. The model requires a sufficiently accurate and general relation between soil emissivity and surface moisture content. A model which requires the soil hydraulic properties as an additional input, but does not need any weather data was developed. The method is shown to be numerically consistent.

A novel adaptive finite time controller for bilateral teleoperation system

NASA Astrophysics Data System (ADS)

Wang, Ziwei; Chen, Zhang; Liang, Bin; Zhang, Bo

2018-03-01

Most bilateral teleoperation researches focus on the system stability within time-delays. However, practical teleoperation tasks require high performances besides system stability, such as convergence rate and accuracy. This paper investigates bilateral teleoperation controller design with transient performances. To ensure the transient performances and system stability simultaneously, an adaptive non-singular fast terminal mode controller is proposed to achieve practical finite-time stability considering system uncertainties and time delays. In addition, a novel switching scheme is introduced, in which way the singularity problem of conventional terminal sliding manifold is avoided. Finally, numerical simulations demonstrate the effectiveness and validity of the proposed method.

Space shuttle solid rocket booster cost-per-flight analysis technique

NASA Technical Reports Server (NTRS)

Forney, J. A.

1979-01-01

A cost per flight computer model is described which considers: traffic model, component attrition, hardware useful life, turnaround time for refurbishment, manufacturing rates, learning curves on the time to perform tasks, cost improvement curves on quantity hardware buys, inflation, spares philosophy, long lead, hardware funding requirements, and other logistics and scheduling constraints. Additional uses of the model include assessing the cost per flight impact of changing major space shuttle program parameters and searching for opportunities to make cost effective management decisions.

Recent advances in phase shifted time averaging and stroboscopic interferometry

NASA Astrophysics Data System (ADS)

Styk, Adam; Józwik, Michał

2016-08-01

Classical Time Averaging and Stroboscopic Interferometry are widely used for MEMS/MOEMS dynamic behavior investigations. Unfortunately both methods require an extensive measurement and data processing strategies in order to evaluate the information on maximum amplitude at a given load of vibrating object. In this paper the modified strategies of data processing in both techniques are introduced. These modifications allow for fast and reliable calculation of searched value, without additional complication of measurement systems. Through the paper the both approaches are discussed and experimentally verified.

Usage Automata

NASA Astrophysics Data System (ADS)

Bartoletti, Massimo

Usage automata are an extension of finite stata automata, with some additional features (e.g. parameters and guards) that improve their expressivity. Usage automata are expressive enough to model security requirements of real-world applications; at the same time, they are simple enough to be statically amenable, e.g. they can be model-checked against abstractions of program usages. We study here some foundational aspects of usage automata. In particular, we discuss about their expressive power, and about their effective use in run-time mechanisms for enforcing usage policies.

XPAR-2 Search Mode Initial Design

DTIC Science & Technology

2013-11-01

by an azimuth sector, an elevation sector, and out to a required maximum range. The frame-time, which is defined as the time it takes the antenna beam...continues its scan, more targets are detected and the measurements are used to form their track files, which are then updated when the beam scans over...every additional target to be tracked. Although the track update rate can be made much faster than that in the TWS mode, it is obvious that there is a

User's manual for three dimensional FDTD version A code for scattering from frequency-independent dielectric materials

NASA Technical Reports Server (NTRS)

Beggs, John H.; Luebbers, Raymond J.; Kunz, Karl S.

1991-01-01

The Finite Difference Time Domain Electromagnetic Scattering Code Version A is a three dimensional numerical electromagnetic scattering code based upon the Finite Difference Time Domain Technique (FDTD). This manual provides a description of the code and corresponding results for the default scattering problem. In addition to the description, the operation, resource requirements, version A code capabilities, a description of each subroutine, a brief discussion of the radar cross section computations, and a discussion of the scattering results.

Methionine toxicity in chicks and poults.

PubMed

Hafez, Y S; Chavez, E; Vohra, P; Kratzer, F H

1978-05-01

In feeding experiments with poults, 2% DL-methionine caused a marked growth depression which could be alleviated by the addition of glycine. Homocystine at an equimolar level depressed growth to a lesser degree than methionine, and this growth depression could be alleviated by glycine. Betaine could alleviate the growth depression of homocystine but not that of methionine. Methionine-fed poults developed a cervical paralysis similar to that of a folic acid deficiency, but the addition of this vitamin at several times the requirement was ineffective in counteracting the toxicity of methionine in either chicks or poults.

2,2'-Biphenols via protecting group-free thermal or microwave-accelerated Suzuki-Miyaura coupling in water.

PubMed

Schmidt, Bernd; Riemer, Martin; Karras, Manfred

2013-09-06

User-friendly protocols for the protecting group-free synthesis of 2,2'-biphenols via Suzuki-Miyaura coupling of o-halophenols and o-boronophenol are presented. The reactions proceed in water in the presence of simple additives such as K2CO3, KOH, KF, or TBAF and with commercially available Pd/C as precatalyst. Expensive or laboriously synthesized ligands or other additives are not required. In the case of bromophenols, efficient rate acceleration and short reaction times were accomplished by microwave irradiation.

46 CFR 42.09-30 - Additional survey requirements for steel-hull vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 2 2011-10-01 2011-10-01 false Additional survey requirements for steel-hull vessels...-30 Additional survey requirements for steel-hull vessels. (a) In addition to the requirements in § 42..., peaks, bilges, machinery spaces, and bunkers shall be examined to determine the condition of the framing...

46 CFR 42.09-30 - Additional survey requirements for steel-hull vessels.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 2 2012-10-01 2012-10-01 false Additional survey requirements for steel-hull vessels. 42.09-30 Section 42.09-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD...-30 Additional survey requirements for steel-hull vessels. (a) In addition to the requirements in § 42...

46 CFR 42.09-30 - Additional survey requirements for steel-hull vessels.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 2 2014-10-01 2014-10-01 false Additional survey requirements for steel-hull vessels. 42.09-30 Section 42.09-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD...-30 Additional survey requirements for steel-hull vessels. (a) In addition to the requirements in § 42...

46 CFR 42.09-30 - Additional survey requirements for steel-hull vessels.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 2 2013-10-01 2013-10-01 false Additional survey requirements for steel-hull vessels. 42.09-30 Section 42.09-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD...-30 Additional survey requirements for steel-hull vessels. (a) In addition to the requirements in § 42...

The cost of sustaining a patient-centered medical home: experience from 2 states.

PubMed

Magill, Michael K; Ehrenberger, David; Scammon, Debra L; Day, Julie; Allen, Tatiana; Reall, Andreu J; Sides, Rhonda W; Kim, Jaewhan

2015-09-01

As medical practices transform to patient-centered medical homes (PCMHs), it is important to identify the ongoing costs of maintaining these "advanced primary care" functions. A key required input is personnel effort. This study's objective was to assess direct personnel costs to practices associated with the staffing necessary to deliver PCMH functions as outlined in the National Committee for Quality Assurance Standards. We developed a PCMH cost dimensions tool to assess costs associated with activities uniquely required to maintain PCMH functions. We interviewed practice managers, nurse supervisors, and medical directors in 20 varied primary care practices in 2 states, guided by the tool. Outcome measures included categories of staff used to perform various PCMH functions, time and personnel costs, and whether practices were delivering PCMH functions. Costs per full-time equivalent primary care clinician associated with PCMH functions varied across practices with an average of $7,691 per month in Utah practices and $9,658 in Colorado practices. PCMH incremental costs per encounter were $32.71 in Utah and $36.68 in Colorado. The average estimated cost per member per month for an assumed panel of 2,000 patients was $3.85 in Utah and $4.83 in Colorado. Identifying costs of maintaining PCMH functions will contribute to effective payment reform and to sustainability of transformation. Maintenance and ongoing support of PCMH functions require additional time and new skills, which may be provided by existing staff, additional staff, or both. Adequate compensation for ongoing and substantial incremental costs is critical for practices to sustain PCMH functions. © 2015 Annals of Family Medicine, Inc.

The Cost of Sustaining a Patient-Centered Medical Home: Experience From 2 States

PubMed Central

Magill, Michael K.; Ehrenberger, David; Scammon, Debra L.; Day, Julie; Allen, Tatiana; Reall, Andreu J.; Sides, Rhonda W.; Kim, Jaewhan

2015-01-01

PURPOSE As medical practices transform to patient-centered medical homes (PCMHs), it is important to identify the ongoing costs of maintaining these “advanced primary care” functions. A key required input is personnel effort. This study’s objective was to assess direct personnel costs to practices associated with the staffing necessary to deliver PCMH functions as outlined in the National Committee for Quality Assurance Standards. METHODS We developed a PCMH cost dimensions tool to assess costs associated with activities uniquely required to maintain PCMH functions. We interviewed practice managers, nurse supervisors, and medical directors in 20 varied primary care practices in 2 states, guided by the tool. Outcome measures included categories of staff used to perform various PCMH functions, time and personnel costs, and whether practices were delivering PCMH functions. RESULTS Costs per full-time equivalent primary care clinician associated with PCMH functions varied across practices with an average of $7,691 per month in Utah practices and $9,658 in Colorado practices. PCMH incremental costs per encounter were $32.71 in Utah and $36.68 in Colorado. The average estimated cost per member per month for an assumed panel of 2,000 patients was $3.85 in Utah and $4.83 in Colorado. CONCLUSIONS Identifying costs of maintaining PCMH functions will contribute to effective payment reform and to sustainability of transformation. Maintenance and ongoing support of PCMH functions require additional time and new skills, which may be provided by existing staff, additional staff, or both. Adequate compensation for ongoing and substantial incremental costs is critical for practices to sustain PCMH functions. PMID:26371263

Effect of adding acid solution on setting time and compressive strength of high calcium fly ash based geopolymer

NASA Astrophysics Data System (ADS)

Antoni, Herianto, Jason Ghorman; Anastasia, Evelin; Hardjito, Djwantoro

2017-09-01

Fly ash with high calcium oxide content when used as the base material in geopolymer concrete could cause flash setting or rapid hardening. However, it might increase the compressive strength of geopolymer concrete. This rapid hardening could cause problems if the geopolymer concrete is used on a large scale casting that requires a long setting time. CaO content can be indicated by pH values of the fly ash, while higher pH is correlated with the rapid setting time of fly ash-based geopolymer. This study investigates the addition of acid solution to reduce the initial pH of the fly ash and to prolong the setting time of the mixture. The acids used in this study are hydrochloric acid (HCl), sulfuric acid (H2 SO4), nitric acid (HNO3) and acetic acid (CH3 COOH). It was found that the addition of acid solution in fly ash was able to decrease the initial pH of fly ash, however, the initial setting time of geopolymer was not reduced. It was even faster than that of the control mixture. The acid type causes various influence, depending on the fly ash properties. In addition, the use of acid solution in fly ash reduces the compressive strength of geopolymer mortar. It is concluded that the addition of acid solution cannot prolong the rapid hardening of high calcium fly ash geopolymer, and it causes adverse effect on the compressive strength.

Recovery of photoinduced reversible dark States utilized for molecular diffusion measurements.

PubMed

Chmyrov, Andriy; Sandén, Tor; Widengren, Jerker

2010-12-15

For a spatially restricted excitation volume, the effective modulation of the excitation in time is influenced by the passage times of the molecules through the excitation volume. By applying an additional time-modulated excitation, the buildup of photoinduced reversible dark states in fluorescent molecules can be made to vary significantly with their passage times through the excitation volume. The variations in the dark state populations are reflected by the time-averaged fluorescence intensity, which thus can be used to characterize the mobilities of the molecules. The concept was experimentally verified by measuring the fluorescence response of freely diffusing cyanine fluorophores (Cy5), undergoing trans-cis isomerization when subject to time-modulated excitation in a focused laser beam. From the fluorescence response, and by applying a simple photodynamic model, the transition times of the Cy5 molecules could be well reproduced when applying different laminar flow speeds through the detection volume. The presented approach puts no constraints on sample concentration, no requirements for high time resolution or sensitivity in the detection, nor requires a high fluorescence brightness of the characterized molecules. This can make the concept useful for a broad range of biomolecular mobility studies.

MagPy: A Python toolbox for controlling Magstim transcranial magnetic stimulators.

PubMed

McNair, Nicolas A

2017-01-30

To date, transcranial magnetic stimulation (TMS) studies manipulating stimulation parameters have largely used blocked paradigms. However, altering these parameters on a trial-by-trial basis in Magstim stimulators is complicated by the need to send regular (1Hz) commands to the stimulator. Additionally, effecting such control interferes with the ability to send TMS pulses or simultaneously present stimuli with high-temporal precision. This manuscript presents the MagPy toolbox, a Python software package that provides full control over Magstim stimulators via the serial port. It is able to maintain this control with no impact on concurrent processing, such as stimulus delivery. In addition, a specially-designed "QuickFire" serial cable is specified that allows MagPy to trigger TMS pulses with very low-latency. In a series of experimental simulations, MagPy was able to maintain uninterrupted remote control over the connected Magstim stimulator across all testing sessions. In addition, having MagPy enabled had no effect on stimulus timing - all stimuli were presented for precisely the duration specified. Finally, using the QuickFire cable, MagPy was able to elicit TMS pulses with sub-millisecond latencies. The MagPy toolbox allows for experiments that require manipulating stimulation parameters from trial to trial. Furthermore, it can achieve this in contexts that require tight control over timing, such as those seeking to combine TMS with fMRI or EEG. Together, the MagPy toolbox and QuickFire serial cable provide an effective means for controlling Magstim stimulators during experiments while ensuring high-precision timing. Copyright © 2016 Elsevier B.V. All rights reserved.

Approximate matching of regular expressions.

PubMed

Myers, E W; Miller, W

1989-01-01

Given a sequence A and regular expression R, the approximate regular expression matching problem is to find a sequence matching R whose optimal alignment with A is the highest scoring of all such sequences. This paper develops an algorithm to solve the problem in time O(MN), where M and N are the lengths of A and R. Thus, the time requirement is asymptotically no worse than for the simpler problem of aligning two fixed sequences. Our method is superior to an earlier algorithm by Wagner and Seiferas in several ways. First, it treats real-valued costs, in addition to integer costs, with no loss of asymptotic efficiency. Second, it requires only O(N) space to deliver just the score of the best alignment. Finally, its structure permits implementation techniques that make it extremely fast in practice. We extend the method to accommodate gap penalties, as required for typical applications in molecular biology, and further refine it to search for sub-strings of A that strongly align with a sequence in R, as required for typical data base searches. We also show how to deliver an optimal alignment between A and R in only O(N + log M) space using O(MN log M) time. Finally, an O(MN(M + N) + N2log N) time algorithm is presented for alignment scoring schemes where the cost of a gap is an arbitrary increasing function of its length.

EliXR-TIME: A Temporal Knowledge Representation for Clinical Research Eligibility Criteria.

PubMed

Boland, Mary Regina; Tu, Samson W; Carini, Simona; Sim, Ida; Weng, Chunhua

2012-01-01

Effective clinical text processing requires accurate extraction and representation of temporal expressions. Multiple temporal information extraction models were developed but a similar need for extracting temporal expressions in eligibility criteria (e.g., for eligibility determination) remains. We identified the temporal knowledge representation requirements of eligibility criteria by reviewing 100 temporal criteria. We developed EliXR-TIME, a frame-based representation designed to support semantic annotation for temporal expressions in eligibility criteria by reusing applicable classes from well-known clinical temporal knowledge representations. We used EliXR-TIME to analyze a training set of 50 new temporal eligibility criteria. We evaluated EliXR-TIME using an additional random sample of 20 eligibility criteria with temporal expressions that have no overlap with the training data, yielding 92.7% (76 / 82) inter-coder agreement on sentence chunking and 72% (72 / 100) agreement on semantic annotation. We conclude that this knowledge representation can facilitate semantic annotation of the temporal expressions in eligibility criteria.

Colorado Water Watch: real-time groundwater monitoring for possible contamination from oil and gas activities.

PubMed

Son, Ji-Hee; Hanif, Asma; Dhanasekar, Ashwin; Carlson, Kenneth H

2018-02-13

Currently, only a few states in the USA (e.g., Colorado and Ohio) require mandatory baseline groundwater sampling from nearby groundwater wells prior to drilling a new oil or gas well. Colorado is the first state to regulate groundwater testing before and after drilling, which requires one pre-drilling sample and two additional post-drilling samples within 6-12 months and 5-6 years of drilling. However, the monitoring method is limited to the state's regulatory agency and to ex situ sampling, which offers only a snapshot in time. To overcome the limitations and increase monitoring performance, a new groundwater monitoring system, Colorado Water Watch (CWW), was introduced as a decision-making tool to support the state's regulatory agency and also to provide real-time groundwater quality data to both the industry and the public. The CWW uses simple in situ water quality sensors based on the surrogate sensing technology that employs an event detection system to screen the incoming data in near real-time.

GPS Moving Vehicle Experiment

NASA Technical Reports Server (NTRS)

Oaks, O. J.; Reid, Wilson; Wright, James; Duffey, Christopher; Williams, Charles; Warren, Hugh; Zeh, Tom; Buisson, James

1996-01-01

The Naval Research Laboratory (NRL) in the development of timing systems for remote locations, had a technical requirement for a Y code (SA/AS) Global Positioning System (GPS) precise time transfer receiver (TTR) which could be used both in a stationary mode or mobile mode. A contract was awarded to the Stanford Telecommunication Corporation (STEL) to build such a device. The Eastern Range (ER) als had a requirement for such a receiver and entered into the contract with NRL for the procurement of additional receivers. The Moving Vehicle Experiment (MVE) described in this paper is the first in situ test of the STEL Model 5401C Time Transfer System in both stationary and mobile operations. The primary objective of the MVE was to test the timing accuracy of the newly developed GPS TTR aboard a moving vessel. To accomplish this objective, a joint experiment was performed with personnel from NRL and the er at the Atlantic Undersea Test and Evaluation Center (AUTEC) test range at Andros Island. Results and discussion of the test are presented in this paper.

40 CFR 80.1613 - Standards and other requirements for gasoline additive manufacturers and blenders.

Code of Federal Regulations, 2014 CFR

2014-07-01

... gasoline additive manufacturers and blenders. 80.1613 Section 80.1613 Protection of Environment... Gasoline Sulfur § 80.1613 Standards and other requirements for gasoline additive manufacturers and blenders. Gasoline additive manufacturers and blenders must meet the following requirements: (a) Gasoline additive...

A Regularized Volumetric Fusion Framework for Large-Scale 3D Reconstruction

NASA Astrophysics Data System (ADS)

Rajput, Asif; Funk, Eugen; Börner, Anko; Hellwich, Olaf

2018-07-01

Modern computational resources combined with low-cost depth sensing systems have enabled mobile robots to reconstruct 3D models of surrounding environments in real-time. Unfortunately, low-cost depth sensors are prone to produce undesirable estimation noise in depth measurements which result in either depth outliers or introduce surface deformations in the reconstructed model. Conventional 3D fusion frameworks integrate multiple error-prone depth measurements over time to reduce noise effects, therefore additional constraints such as steady sensor movement and high frame-rates are required for high quality 3D models. In this paper we propose a generic 3D fusion framework with controlled regularization parameter which inherently reduces noise at the time of data fusion. This allows the proposed framework to generate high quality 3D models without enforcing additional constraints. Evaluation of the reconstructed 3D models shows that the proposed framework outperforms state of art techniques in terms of both absolute reconstruction error and processing time.

Time to Evolve? Potential Evolutionary Responses of Fraser River Sockeye Salmon to Climate Change and Effects on Persistence

PubMed Central

Reed, Thomas E.; Schindler, Daniel E.; Hague, Merran J.; Patterson, David A.; Meir, Eli; Waples, Robin S.; Hinch, Scott G.

2011-01-01

Evolutionary adaptation affects demographic resilience to climate change but few studies have attempted to project changes in selective pressures or quantify impacts of trait responses on population dynamics and extinction risk. We used a novel individual-based model to explore potential evolutionary changes in migration timing and the consequences for population persistence in sockeye salmon Oncorhynchus nerka in the Fraser River, Canada, under scenarios of future climate warming. Adult sockeye salmon are highly sensitive to increases in water temperature during their arduous upriver migration, raising concerns about the fate of these ecologically, culturally, and commercially important fish in a warmer future. Our results suggest that evolution of upriver migration timing could allow these salmon to avoid increasingly frequent stressful temperatures, with the odds of population persistence increasing in proportion to the trait heritability and phenotypic variance. With a simulated 2°C increase in average summer river temperatures by 2100, adult migration timing from the ocean to the river advanced by ∼10 days when the heritability was 0.5, while the risk of quasi-extinction was only 17% of that faced by populations with zero evolutionary potential (i.e., heritability fixed at zero). The rates of evolution required to maintain persistence under simulated scenarios of moderate to rapid warming are plausible based on estimated heritabilities and rates of microevolution of timing traits in salmon and related species, although further empirical work is required to assess potential genetic and ecophysiological constraints on phenological adaptation. These results highlight the benefits to salmon management of maintaining evolutionary potential within populations, in addition to conserving key habitats and minimizing additional stressors where possible, as a means to build resilience to ongoing climate change. More generally, they demonstrate the importance and feasibility of considering evolutionary processes, in addition to ecology and demography, when projecting population responses to environmental change. PMID:21738573

Cleaner emissions from a DI diesel engine fueled with waste plastic oil derived from municipal solid waste under the influence of n-pentanol addition, cold EGR, and injection timing.

PubMed

Damodharan, Dillikannan; Sathiyagnanam, Amudhavalli Paramasivam; Rajesh Kumar, Babu; Ganesh, Kuttalam Chidambaradhanu

2018-05-01

Urban planning and development is a decisive factor that increases the automobile numbers which leads to increased energy demand across the globe. In order to meet the escalating requirements of energy, it is necessary to find viable alternatives. Waste plastic oil (WPO) is one such alternative which has dual benefits as it reduces the environmental pollution caused by plastic waste and it could possibly meet the energy requirement along with fossil fuels. The study attempted to reduce emissions from a DI diesel engine fueled with WPO using 30% by volume of n-pentanol with fossil diesel (WPO70P30). EGR (10, 20, and 30%) and injection timing modifications were made with the intention to find optimum engine operating conditions. The experimental results indicated that addition of renewable component like n-pentanol had improved the combustion characteristics by igniting WPO more homogeneously producing a higher premixed combustion phase. Smoke density for WPO70P30 was found to be twice lower than that of neat WPO at standard injection timing of 23°CA bTDC at any given EGR rate, NOx emissions were slightly on the higher side about 12% for WPO70P30 blend against WPO at same operating conditions. WPO70P30 showed lowest smoke and carbon monoxide emissions than diesel and WPO while delivering BTE's higher than WPO and closer to diesel at all EGR and injection timings. However NOx and HC emissions increased with n-pentanol addition. The use of EGR reduced NOx emissions but was found to aggravate other emissions. It was concluded WPO70P30 can be favorably used in a DI diesel engine at the engines advanced injection timing for better performance than diesel with a slight penalty in NOx emissions.

Real-Time Processing of ASL Signs: Delayed First Language Acquisition Affects Organization of the Mental Lexicon

ERIC Educational Resources Information Center

Lieberman, Amy M.; Borovsky, Arielle; Hatrak, Marla; Mayberry, Rachel I.

2015-01-01

Sign language comprehension requires visual attention to the linguistic signal and visual attention to referents in the surrounding world, whereas these processes are divided between the auditory and visual modalities for spoken language comprehension. Additionally, the age-onset of first language acquisition and the quality and quantity of…

76 FR 59241 - Foreign Futures and Options Contracts on a Non-Narrow-Based Security Index; Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-26

... controls on trading; information and data relating to the index, including the design, computation and... futures contract raises novel or complex issues that require additional time for review, or if the foreign... composition, computation, or method of selection of component entities of an index referenced and defined in...

26 CFR 1.1244(d)-3 - Stock dividend, recapitalizations, changes in name, etc.

Code of Federal Regulations, 2010 CFR

2010-04-01

... time of the issuance. In 1960, C purchases an additional 200 shares of such stock from another... will be treated as meeting such requirements. Assuming all the shares with respect to which the dividend is received have equal rights to dividends, such part is the number of shares which bears the same...

75 FR 6237 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... additional one hour after the decision making cut off time of 5:30 p.m. to submit a CEA to the various.... The Exchange will continue to enforce the 5:30 p.m. decision making requirement, while also allowing..., processing information with respect to, and facilitating transactions in securities, to remove impediments to...

49 CFR 173.302a - Additional requirements for shipment of nonliquefied (permanent) compressed gases in...

Code of Federal Regulations, 2011 CFR

2011-10-01

... elastic expansion was determined at the time of the last test or retest by the water jacket method. (3) Either the average wall stress or the maximum wall stress does not exceed the wall stress limitation shown in the following table: Type of steel Average wall stress limitation Maximum wall stress...

29 CFR 1926.251 - Rigging equipment for material handling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... splices, the U-bolt shall be applied so that the “U” section is in contact with the dead end of the rope... laid grommets and endless slings shall have a minimum circumferential length of 96 times their body... body of the rope using at least two additional tucks (which will require a tail length of approximately...

Coral Reefs, Convicts, Cadavers, Coffee Shops and Couture: Customizing Experiential Learning to Increase Comfort and Engagement

ERIC Educational Resources Information Center

Grabowsky, Gail L.; Hargis, Jace; Davidson, Janet; Paynter, Allison; Suh, Junghwa; Wright, Claire

2017-01-01

Experiential learning (EL) can offer a high impact educational opportunity that benefits students from diverse backgrounds, creating an inclusive learning environment. Barriers to the generalization of EL can include a lack of institutional support, risk avoidance, time, and faculty instructional ability. As well EL require additional efforts from…

20 CFR 645.230 - What general fiscal and administrative rules apply to the use of Federal funds?

Code of Federal Regulations, 2011 CFR

2011-04-01

... Acquisition Regulation (FAR) at 48 CFR Part 31. (d) Information technology costs. In addition to the allowable cost provisions identified in § 645.235 of this subpart, the costs of information technology—computer... compliant.” To meet this requirement, information technology must be able to accurately process date/time...

20 CFR 645.230 - What general fiscal and administrative rules apply to the use of Federal funds?

Code of Federal Regulations, 2014 CFR

2014-04-01

... Acquisition Regulation (FAR) at 48 CFR Part 31. (d) Information technology costs. In addition to the allowable cost provisions identified in § 645.235 of this subpart, the costs of information technology—computer... compliant.” To meet this requirement, information technology must be able to accurately process date/time...

20 CFR 645.230 - What general fiscal and administrative rules apply to the use of Federal funds?

Code of Federal Regulations, 2012 CFR

2012-04-01

... Acquisition Regulation (FAR) at 48 CFR Part 31. (d) Information technology costs. In addition to the allowable cost provisions identified in § 645.235 of this subpart, the costs of information technology—computer... compliant.” To meet this requirement, information technology must be able to accurately process date/time...

20 CFR 645.230 - What general fiscal and administrative rules apply to the use of Federal funds?

Code of Federal Regulations, 2013 CFR

2013-04-01

... Acquisition Regulation (FAR) at 48 CFR Part 31. (d) Information technology costs. In addition to the allowable cost provisions identified in § 645.235 of this subpart, the costs of information technology—computer... compliant.” To meet this requirement, information technology must be able to accurately process date/time...

20 CFR 645.230 - What general fiscal and administrative rules apply to the use of Federal funds?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Acquisition Regulation (FAR) at 48 CFR Part 31. (d) Information technology costs. In addition to the allowable cost provisions identified in § 645.235 of this subpart, the costs of information technology—computer... compliant.” To meet this requirement, information technology must be able to accurately process date/time...

Idea Generation and Exploration: Benefits and Limitations of the Policy Delphi Research Method

ERIC Educational Resources Information Center

Franklin, Kathy K.; Hart, Jan K.

2007-01-01

Researchers use the policy Delphi method to explore a complex topic with little historical context that requires expert opinion to fully understand underlying issues. The benefit of this research technique is the use of experts who have more timely information than can be gleamed from extant literature. Additionally, those experts place…

A Quantitative Study of the Resultant Differences between Additive Practices and Reductive Practices in Data Requirements Gathering

ERIC Educational Resources Information Center

Johnson, Gerald

2016-01-01

With the increase in technology in all facets of our lives and work, there is an ever increasing set of expectations that people have regarding information availability, response time, and dependability. While expectations are affected by gender, age, experience, industry, and other factors, people have expectations of technology, and from…

75 FR 59935 - Investigational New Drug Safety Reporting Requirements for Human Drug and Biological Products and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... safety reporting for human drug products: Janet Norden, Center for Drug Evaluation and Research, Food and... for Biologics Evaluation and Research, Food and Drug Administration,1401 Rockville Pike, suite 200N..., 2003. At the request of industry, and to provide all interested persons additional time to comment, the...

The Challenges to Human Resources Development of Libraries in Times of Radical and Generational Changes.

ERIC Educational Resources Information Center

Muller, Uta

Librarianship has undergone a radical change in recent years, which will be continued in the future. Whereas previously the administration of media was most important, nowadays an ever increasing willingness to provide a service is required. In addition to the essential restructuring of libraries, a generational change is taking place within the…

Comprehensive K-3 Reading Policy: Fundamental Principles. ExcelinEd Policy Toolkit, 2017

ERIC Educational Resources Information Center

Foundation for Excellence in Education, 2017

2017-01-01

A Comprehensive K-3 Reading Policy establishes intensive reading intervention for K-3 students to ensure they read on grade level by the end of third grade. The policy then requires third grade students to demonstrate sufficient reading skills for promotion to fourth grade. Retention provides struggling readers the additional time and intensive…

Assurance of lubricant supply in wet-lubricated space bearings

NASA Technical Reports Server (NTRS)

Glassow, F. A.

1976-01-01

Conventional lubrication techniques appear to be satisfactory, but rigorous proof of meeting a ten-year life requirement is lacking. One approach provides additional lubricant only when commanded from ground control, while the other passively augments lubrication at all times. Each technique has specific advantages, and selection should be related to the application to obtain optimum performance.

English for New Citizens: Contributions of a Learner-Centered Vocational ESL Framework

ERIC Educational Resources Information Center

Arnold, Lynnette

2014-01-01

As immigration reform is on the table for the first time in two decades, proposals are being made involving a path to citizenship for the 12 million undocumented immigrants now in the country. This article suggests that, in addition to helping these immigrants meet the English-language requirement for citizenship, comprehensive immigration reform…

The Power Dynamics and Politics of Survey Design: Measuring Workload Associated with Teaching, Administering and Supporting Work-Integrated Learning Courses

ERIC Educational Resources Information Center

Clark, Lindie; Rowe, Anna; Cantori, Alex; Bilgin, Ayse; Mukuria, Valentine

2016-01-01

Work-integrated learning (WIL) courses can be more time consuming and resource intensive to design, teach, administer and support than classroom-based courses, as they generally require different curricula and pedagogical approaches as well as additional administrative and pastoral responsibilities. Workload and resourcing issues are reported as…

A Rotating Space Interferometer with Variable Baselines and Low Power Consumption

NASA Technical Reports Server (NTRS)

Gezari, Daniel Y.

1999-01-01

A new concept is presented here for a large, rotating space interferometer which would achieve full u, v plane coverage with reasonably uniform integration times, yet once set in motion no additional energy would be required to change collector separations, maintain constant baseline rotation rates, or to counteract centrifugal forces on the collectors.

Novel microwave readout for phase qubits

NASA Astrophysics Data System (ADS)

Kumar, Shwetank; Steffen, Matthias; Rothwell, Mary-Beth; Rozen, James; Keefe, George; Ketchen, Mark

2010-03-01

We present a novel microwave based readout for a phase qubit which circumvents loss mechanisms that have been shown to impact qubit coherence times. Additionally, this new technique facilitates multiplexing of qubits thereby reducing the number of cryogenic wires required for operating the qubits. The basic operation of the circuit will be discussed and compared with experimental data.

Live Action Role Play and the Development of Teacher Competences: Evaluation of "Everyday Life in the Classroom"

ERIC Educational Resources Information Center

Imhof, Margarete; Starker, Ulrike; Spaude, Elena

2016-01-01

Building on Dörner's (1996) theory of complex problem-solving, a learning scenario for teacher students was created and tested. Classroom management is interpreted as a complex problem, which requires the integration of competing interests and tackling multiple, simultaneous tasks under time pressure and with limited information. In addition,…

A cavity radiometer for Earth albedo measurement, phase 1

NASA Technical Reports Server (NTRS)

1987-01-01

Radiometric measurements of the directional albedo of the Earth requires a detector with a flat response from 0.2 to 50 microns, a response time of about 2 seconds, a sensitivity of the order of 0.02 mw/sq cm, and a measurement uncertainty of less than 5 percent. Absolute cavity radiometers easily meet the spectral response and accuracy requirements for Earth albedo measurements, but the radiometers available today lack the necessary sensitivity and response time. The specific innovations addressed were the development of a very low thermal mass cavity and printed/deposited thermocouple sensing elements which were incorporated into the radiometer design to produce a sensitive, fast response, absolute radiometer. The cavity is applicable to the measurement of the reflected and radiated fluxes from the Earth surface and lower atmosphere from low Earth orbit satellites. The effort consisted of requirements and thermal analysis; design, construction, and test of prototype elements of the black cavity and sensor elements to show proof-of-concept. The results obtained indicate that a black body cavity sensor that has inherently a flat response from 0.2 to 50 microns can be produced which has a sensitivity of at least 0.02 mw/sq cm per micro volt ouput and with a time constant of less than two seconds. Additional work is required to develop the required thermopile.

Risk-based requirements management framework with applications to assurance cases

NASA Astrophysics Data System (ADS)

Feng, D.; Eyster, C.

The current regulatory approach for assuring device safety primarily focuses on compliance with prescriptive safety regulations and relevant safety standards. This approach, however, does not always lead to a safe system design even though safety regulations and standards have been met. In the medical device industry, several high profile recalls involving infusion pumps have prompted the regulatory agency to reconsider how device safety should be managed, reviewed and approved. An assurance case has been cited as a promising tool to address this growing concern. Assurance cases have been used in safety-critical systems for some time. Most assurance cases, if not all, in literature today are developed in an ad hoc fashion, independent from risk management and requirement development. An assurance case is a resource-intensive endeavor that requires additional effort and documentation from equipment manufacturers. Without a well-organized requirements infrastructure in place, such “ additional effort” can be substantial, to the point where the cost of adoption outweighs the benefit of adoption. In this paper, the authors present a Risk-Based Requirements and Assurance Management (RBRAM) methodology. The RBRAM is an elaborate framework that combines Risk-Based Requirements Management (RBRM) with assurance case methods. Such an integrated framework can help manufacturers leverage an existing risk management to present a comprehensive assurance case with minimal additional effort while providing a supplementary means to reexamine the integrity of the system design in terms of the mission objective. Although the example used is from the medical industry, the authors believe that the RBRAM methodology underlines the fundamental principle of risk management, and offers a simple, yet effective framework applicable to aerospace industry, perhaps, to any industry.

46 CFR 42.09-35 - Additional survey requirements for wood-hull vessels.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 2 2013-10-01 2013-10-01 false Additional survey requirements for wood-hull vessels. 42.09-35 Section 42.09-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES... Additional survey requirements for wood-hull vessels. (a) In addition to the requirements in § 42.09-25, the...

46 CFR 42.09-35 - Additional survey requirements for wood-hull vessels.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 2 2012-10-01 2012-10-01 false Additional survey requirements for wood-hull vessels. 42.09-35 Section 42.09-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES... Additional survey requirements for wood-hull vessels. (a) In addition to the requirements in § 42.09-25, the...

46 CFR 42.09-35 - Additional survey requirements for wood-hull vessels.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 2 2014-10-01 2014-10-01 false Additional survey requirements for wood-hull vessels. 42.09-35 Section 42.09-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES... Additional survey requirements for wood-hull vessels. (a) In addition to the requirements in § 42.09-25, the...

46 CFR 42.09-35 - Additional survey requirements for wood-hull vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Additional survey requirements for wood-hull vessels. 42.09-35 Section 42.09-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES... Additional survey requirements for wood-hull vessels. (a) In addition to the requirements in § 42.09-25, the...

46 CFR 42.09-30 - Additional survey requirements for steel-hull vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Additional survey requirements for steel-hull vessels...-30 Additional survey requirements for steel-hull vessels. (a) In addition to the requirements in § 42...) When the vessel is in drydock, the hull plating, etc., shall be examined. (c) The holds, 'tween decks...

46 CFR 35.03-25 - Additional requirements for hybrid work vests.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Additional requirements for hybrid work vests. 35.03-25 Section 35.03-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Work Vests § 35.03-25 Additional requirements for hybrid work vests. (a) In addition to the other requirements in...

46 CFR 35.03-25 - Additional requirements for hybrid work vests.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Additional requirements for hybrid work vests. 35.03-25 Section 35.03-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Work Vests § 35.03-25 Additional requirements for hybrid work vests. (a) In addition to the other requirements in...

46 CFR 35.03-25 - Additional requirements for hybrid work vests.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Additional requirements for hybrid work vests. 35.03-25 Section 35.03-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Work Vests § 35.03-25 Additional requirements for hybrid work vests. (a) In addition to the other requirements in...

46 CFR 35.03-25 - Additional requirements for hybrid work vests.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Additional requirements for hybrid work vests. 35.03-25 Section 35.03-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Work Vests § 35.03-25 Additional requirements for hybrid work vests. (a) In addition to the other requirements in...

46 CFR 35.03-25 - Additional requirements for hybrid work vests.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Additional requirements for hybrid work vests. 35.03-25 Section 35.03-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Work Vests § 35.03-25 Additional requirements for hybrid work vests. (a) In addition to the other requirements in...

46 CFR 42.09-35 - Additional survey requirements for wood-hull vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 2 2011-10-01 2011-10-01 false Additional survey requirements for wood-hull vessels. 42.09-35 Section 42.09-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES... Additional survey requirements for wood-hull vessels. (a) In addition to the requirements in § 42.09-25, the...

Psychological distress following a motor vehicle crash: evidence from a statewide retrospective study examining settlement times and costs of compensation claims.

PubMed

Guest, Rebecca; Tran, Yvonne; Gopinath, Bamini; Cameron, Ian D; Craig, Ashley

2017-09-05

To determine whether psychological distress associated with musculoskeletal injuries sustained in a motor vehicle crash (MVC), regardless of time of onset, impacts compensation outcomes such as claim settlement times and costs. Second, to identify factors routinely collected by insurance companies that contribute to psychological distress during the compensation process. Statewide retrospective study. Analysis of the New South Wales statewide (Australia) injury register for MVC survivors who lodged a compensation claim from 2011 to 2013. 6341 adults who sustained a musculoskeletal injury and who settled a claim for injury after an MVC. Participants included those diagnosed with psychological distress (n=607) versus those not (n=5734). Time to settlement and total costs of claims, as well as socio-demographic and injury characteristics that may contribute to elevated psychological distress, such as socio-economic disadvantage, and injury severity. Psychological distress in those with a musculoskeletal injury was associated with significantly longer settlement times (an additional 17 weeks) and considerably higher costs (an additional $A41 575.00 or 4.3 times more expensive). Multivariate logistic regression analysis identified risk factors for psychological distress including being female, social disadvantage, unemployment prior to the claim, not being at fault in the MVC, requiring ambulance transportation and rehabilitation as part of recovery. Results provide compelling evidence that psychological distress has an adverse impact on people with musculoskeletal injury as they progress through compensation. Findings suggest that additional resources should be directed toward claimants who are at risk (eg, the socially disadvantaged or those unemployed prior to the claim), the major aim being to reduce risk of psychological distress, such as post-traumatic stress disorder, and associated risk of increased settlement times and claim costs. Prospective studies are now required that investigate treatment strategies for those at risk of psychological distress associated with an MVC. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Optimal management of perimenopausal depression

PubMed Central

Parry, Barbara L

2010-01-01

Only recently has the perimenopause become recognized as a time when women are at risk for new onset and recurrence of major depression. Untreated depression at this time not only exacerbates the course of a depressive illness, but also puts women at increased risk for sleep disorders, cardiovascular disease, diabetes, and osteoporosis. Although antidepressant medication is the mainstay of treatment, adjunctive therapy, especially with estrogen replacement, may be indicated in refractory cases, and may speed the onset of antidepressant action. Many, but not all, studies, report that progesterone antagonizes the beneficial effects of estrogen. Although some antidepressants improve vasomotor symptoms, in general they are not as effective as estrogen alone for relieving these symptoms. Estrogen alone, however, does not generally result in remission of major depression in most (but not all) studies, but may provide benefit to some women with less severe symptoms if administered in therapeutic ranges. The selective serotonin reuptake inhibitors (SSRIs) in addition to estrogen are usually more beneficial in improving mood than SSRIs or estrogen treatment alone for major depression, whereas the selective norepinephrine and serotonin reuptake inhibitors do not require the addition of estrogen to exert their antidepressant effects in menopausal depression. In addition to attention to general health, hormonal status, and antidepressant treatment, the optimal management of perimenopausal depression also requires attention to the individual woman’s psychosocial and spiritual well being. PMID:21072307

Multipurpose Vacuum Induction Processing System

NASA Astrophysics Data System (ADS)

Govindaraju, M.; Kulkarni, Deepak; Balasubramanian, K.

2012-11-01

Multipurpose vacuum processing systems are cost effective; occupy less space, multiple functional under one roof and user friendly. A multipurpose vacuum induction system was designed, fabricated and installed in a record time of 6 months time at NFTDC Hyderabad. It was designed to function as a) vacuum induction melting/refining of oxygen free electronic copper/pure metals, b) vacuum induction melting furnace for ferrous materials c) vacuum induction melting for non ferrous materials d) large vacuum heat treatment chamber by resistance heating (by detachable coil and hot zone) e) bottom discharge vacuum induction melting system for non ferrous materials f) Induction heat treatment system and g) directional solidification /investment casting. It contains provision for future capacity addition. The attachments require to manufacture multiple shaped castings and continuous rod casting can be added whenever need arises. Present capacity is decided on the requirement for 10years of development path; presently it has 1.2 ton liquid copper handling capacity. It is equipped with provision for capacity addition up to 2 ton liquid copper handling capacity in future. Provision is made to carry out the capacity addition in easy steps quickly. For easy operational maintenance and troubleshooting, design was made in easily detachable sections. High vacuum system is also is detachable, independent and easily movable which is first of its kind in the country. Detailed design parameters, advantages and development history are presented in this paper.

Pediatric procedural sedation with ketamine: time to discharge after intramuscular versus intravenous administration.

PubMed

Ramaswamy, Preeti; Babl, Franz E; Deasy, Conor; Sharwood, Lisa N

2009-02-01

Ketamine is an attractive agent for pediatric procedural sedation. There are limited data on time to discharge comparing intramuscular (IM) vs. intravenous (IV) ketamine. The authors set out to determine whether IM or IV ketamine leads to quicker discharge from the emergency department (ED) and how side effect profiles compare. All patients who had received ketamine IM or IV at a tertiary children's hospital ED during the 3-year study period (2004-2007) were identified. Prospective sedation registry data, retrospective medical records, and administrative data were reviewed for drug dosages, use of additional agents, time of drug administration to discharge, total ED time (triage to discharge), and adverse events. A subgroup analysis for patients requiring five or fewer sutures (short suture group) was performed. A total of 229 patients were enrolled (60% male) with median age of 2.8 years (IQR =1.8-4.3 years) and median weight of 15.7 kg (range = 8.7-74 kg). Ketamine was most frequently employed for laceration repair (80%) and foreign body removal (9%). Overall, 48% received ketamine IM and 52% received it IV. In the short-suture subgroup, 52% received ketamine IM, while 48% received it IV. Multivariate linear regression analysis determined time from drug administration to patient discharge as 21 minutes shorter for IV compared with IM administration, adjusted for age and number of additional doses (R(2) = -0.35; 95% CI = -0.5 to -0.19; p < 0.001). Total time in the ED (triage to discharge) comparing IV versus IM administration, adjusting for age and gender and number of additional doses, was not significantly different (p = 0.16). In the short-suture subgroup, time to discharge from administration was also shorter in the IV ketamine group (R(2) = -0.454; 95%CI = -0.66 to -0.25; p < 0.001) but similar for total time in ED (p = 0.16). Overall, adverse events occurred in 35% (95% CI = 27% to 45%) of the IM group and 20% (95% CI = 13% to 28%) of the IV group (p = 0.01). Only one patient required brief bag-mask ventilation. In this institution, time from drug injection to discharge was shorter in the IV compared to IM ketamine group, both overall and for the short-suture group. However, time from triage to discharge was similar.

Discontinuous Spectral Difference Method for Conservation Laws on Unstructured Grids

NASA Technical Reports Server (NTRS)

Liu, Yen; Vinokur, Marcel

2004-01-01

A new, high-order, conservative, and efficient discontinuous spectral finite difference (SD) method for conservation laws on unstructured grids is developed. The concept of discontinuous and high-order local representations to achieve conservation and high accuracy is utilized in a manner similar to the Discontinuous Galerkin (DG) and the Spectral Volume (SV) methods, but while these methods are based on the integrated forms of the equations, the new method is based on the differential form to attain a simpler formulation and higher efficiency. Conventional unstructured finite-difference and finite-volume methods require data reconstruction based on the least-squares formulation using neighboring point or cell data. Since each unknown employs a different stencil, one must repeat the least-squares inversion for every point or cell at each time step, or to store the inversion coefficients. In a high-order, three-dimensional computation, the former would involve impractically large CPU time, while for the latter the memory requirement becomes prohibitive. In addition, the finite-difference method does not satisfy the integral conservation in general. By contrast, the DG and SV methods employ a local, universal reconstruction of a given order of accuracy in each cell in terms of internally defined conservative unknowns. Since the solution is discontinuous across cell boundaries, a Riemann solver is necessary to evaluate boundary flux terms and maintain conservation. In the DG method, a Galerkin finite-element method is employed to update the nodal unknowns within each cell. This requires the inversion of a mass matrix, and the use of quadratures of twice the order of accuracy of the reconstruction to evaluate the surface integrals and additional volume integrals for nonlinear flux functions. In the SV method, the integral conservation law is used to update volume averages over subcells defined by a geometrically similar partition of each grid cell. As the order of accuracy increases, the partitioning for 3D requires the introduction of a large number of parameters, whose optimization to achieve convergence becomes increasingly more difficult. Also, the number of interior facets required to subdivide non-planar faces, and the additional increase in the number of quadrature points for each facet, increases the computational cost greatly.

MO-FG-CAMPUS-JeP3-01: A Statistical Model for Analyzing the Rotational Error of Single Iso-Center Technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, J; Dept of Radiation Oncology, New York Weill Cornell Medical Ctr, New York, NY

Purpose: To develop a generalized statistical model that incorporates the treatment uncertainty from the rotational error of single iso-center technique, and calculate the additional PTV (planning target volume) margin required to compensate for this error. Methods: The random vectors for setup and additional rotation errors in the three-dimensional (3D) patient coordinate system were assumed to follow the 3D independent normal distribution with zero mean, and standard deviations σx, σy, σz, for setup error and a uniform σR for rotational error. Both random vectors were summed, normalized and transformed to the spherical coordinates to derive the chi distribution with 3 degreesmore » of freedom for the radical distance ρ. PTV margin was determined using the critical value of this distribution for 0.05 significant level so that 95% of the time the treatment target would be covered by ρ. The additional PTV margin required to compensate for the rotational error was calculated as a function of σx, σy, σz and σR. Results: The effect of the rotational error is more pronounced for treatments that requires high accuracy/precision like stereotactic radiosurgery (SRS) or stereotactic body radiotherapy (SBRT). With a uniform 2mm PTV margin (or σx =σy=σz=0.7mm), a σR=0.32mm will decrease the PTV coverage from 95% to 90% of the time, or an additional 0.2mm PTV margin is needed to prevent this loss of coverage. If we choose 0.2 mm as the threshold, any σR>0.3mm will lead to an additional PTV margin that cannot be ignored, and the maximal σR that can be ignored is 0.0064 rad (or 0.37°) for iso-to-target distance=5cm, or 0.0032 rad (or 0.18°) for iso-to-target distance=10cm. Conclusions: The rotational error cannot be ignored for high-accuracy/-precision treatments like SRS/SBRT, particularly when the distance between the iso-center and target is large.« less

Atlas-Based Segmentation Improves Consistency and Decreases Time Required for Contouring Postoperative Endometrial Cancer Nodal Volumes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, Amy V.; Department of Radiation Oncology, St. Luke's-Roosevelt Hospital, New York, NY; Wortham, Angela

2011-03-01

Purpose: Accurate target delineation of the nodal volumes is essential for three-dimensional conformal and intensity-modulated radiotherapy planning for endometrial cancer adjuvant therapy. We hypothesized that atlas-based segmentation ('autocontouring') would lead to time savings and more consistent contours among physicians. Methods and Materials: A reference anatomy atlas was constructed using the data from 15 postoperative endometrial cancer patients by contouring the pelvic nodal clinical target volume on the simulation computed tomography scan according to the Radiation Therapy Oncology Group 0418 trial using commercially available software. On the simulation computed tomography scans from 10 additional endometrial cancer patients, the nodal clinical targetmore » volume autocontours were generated. Three radiation oncologists corrected the autocontours and delineated the manual nodal contours under timed conditions while unaware of the other contours. The time difference was determined, and the overlap of the contours was calculated using Dice's coefficient. Results: For all physicians, manual contouring of the pelvic nodal target volumes and editing the autocontours required a mean {+-} standard deviation of 32 {+-} 9 vs. 23 {+-} 7 minutes, respectively (p = .000001), a 26% time savings. For each physician, the time required to delineate the manual contours vs. correcting the autocontours was 30 {+-} 3 vs. 21 {+-} 5 min (p = .003), 39 {+-} 12 vs. 30 {+-} 5 min (p = .055), and 29 {+-} 5 vs. 20 {+-} 5 min (p = .0002). The mean overlap increased from manual contouring (0.77) to correcting the autocontours (0.79; p = .038). Conclusion: The results of our study have shown that autocontouring leads to increased consistency and time savings when contouring the nodal target volumes for adjuvant treatment of endometrial cancer, although the autocontours still required careful editing to ensure that the lymph nodes at risk of recurrence are properly included in the target volume.« less

Advanced Chemistry Collection, 2nd Edition

NASA Astrophysics Data System (ADS)

2001-11-01

Software requirements are given in Table 3. Some programs have additional special requirements. Please see the individual program abstracts at JCE Online or the documentation included on the CD-ROM for more specific information. Table 3. General software requirements for the Advanced Chemistry Collection.

Literature Cited

1. General Chemistry Collection, 5th ed.; J. Chem. Educ. Software, 2001, SP16.
2. Advanced Chemistry Collection; J. Chem. Educ. Software, 2001, SP28.

Unsupervised markerless 3-DOF motion tracking in real time using a single low-budget camera.

PubMed

Quesada, Luis; León, Alejandro J

2012-10-01

Motion tracking is a critical task in many computer vision applications. Existing motion tracking techniques require either a great amount of knowledge on the target object or specific hardware. These requirements discourage the wide spread of commercial applications based on motion tracking. In this paper, we present a novel three degrees of freedom motion tracking system that needs no knowledge on the target object and that only requires a single low-budget camera that can be found installed in most computers and smartphones. Our system estimates, in real time, the three-dimensional position of a nonmodeled unmarked object that may be nonrigid, nonconvex, partially occluded, self-occluded, or motion blurred, given that it is opaque, evenly colored, enough contrasting with the background in each frame, and that it does not rotate. Our system is also able to determine the most relevant object to track in the screen. Our proposal does not impose additional constraints, therefore it allows a market-wide implementation of applications that require the estimation of the three position degrees of freedom of an object.

Response Time Analysis and Test of Protection System Instrument Channels for APR1400 and OPR1000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Chang Jae; Han, Seung; Yun, Jae Hee

2015-07-01

Safety limits are required to maintain the integrity of physical barriers designed to prevent the uncontrolled release of radioactive materials in nuclear power plants. The safety analysis establishes two critical constraints that include an analytical limit in terms of a measured or calculated variable, and a specific time after the analytical limit is reached to begin protective action. Keeping with the nuclear regulations and industry standards, satisfying these two requirements will ensure that the safety limit will not be exceeded during the design basis event, either an anticipated operational occurrence or a postulated accident. Various studies on the setpoint determinationmore » methodology for the safety-related instrumentation have been actively performed to ensure that the requirement of the analytical limit is satisfied. In particular, the protection setpoint methodology for the advanced power reactor 1400 (APP1400) and the optimized power reactor 1000 (OPR1000) has been recently developed to cover both the design basis event and the beyond design basis event. The developed setpoint methodology has also been quantitatively validated using specific computer programs and setpoint calculations. However, the safety of nuclear power plants cannot be fully guaranteed by satisfying the requirement of the analytical limit. In spite of the response time verification requirements of nuclear regulations and industry standards, it is hard to find the studies on the systematically integrated methodology regarding the response time evaluation. In cases of APR1400 and OPR1000, the response time analysis for the plant protection system is partially included in the setpoint calculation and the response time test is separately performed via the specific plant procedure. The test technique has a drawback which is the difficulty to demonstrate completeness of timing test. The analysis technique has also a demerit of resulting in extreme times that not actually possible. Thus, the establishment of the systematic response time evaluation methodology is needed to justify the conformance to the response time requirement used in the safety analysis. This paper proposes the response time evaluation methodology for APR1400 and OPR1000 using the combined analysis and test technique to confirm that the plant protection system can meet the analytical response time assumed in the safety analysis. In addition, the results of the quantitative evaluation performed for APR1400 and OPR1000 are presented in this paper. The proposed response time analysis technique consists of defining the response time requirement, determining the critical signal path for the trip parameter, allocating individual response time to each component on the signal path, and analyzing the total response time for the trip parameter, and demonstrates that the total analyzed response time does not exceed the response time requirement. The proposed response time test technique is composed of defining the response time requirement, determining the critical signal path for the trip parameter, determining the test method for each component on the signal path, performing the response time test, and demonstrates that the total test result does not exceed the response time requirement. The total response time should be tested in a single test that covers from the sensor to the final actuation device on the instrument channel. When the total channel is not tested in a single test, separate tests on groups of components or single components including the total instrument channel shall be combined to verify the total channel response. For APR1400 and OPR1000, the ramp test technique is used for the pressure and differential pressure transmitters and the step function testing technique is applied to the signal processing equipment and final actuation device. As a result, it can be demonstrated that the response time requirement is satisfied by the combined analysis and test technique. Therefore, the proposed methodology in this paper plays a crucial role in guaranteeing the safety of the nuclear power plants systematically satisfying one of two critical requirements from the safety analysis. (authors)« less

Limitations of Reliability for Long-Endurance Human Spaceflight

NASA Technical Reports Server (NTRS)

Owens, Andrew C.; de Weck, Olivier L.

2016-01-01

Long-endurance human spaceflight - such as missions to Mars or its moons - will present a never-before-seen maintenance logistics challenge. Crews will be in space for longer and be farther way from Earth than ever before. Resupply and abort options will be heavily constrained, and will have timescales much longer than current and past experience. Spare parts and/or redundant systems will have to be included to reduce risk. However, the high cost of transportation means that this risk reduction must be achieved while also minimizing mass. The concept of increasing system and component reliability is commonly discussed as a means to reduce risk and mass by reducing the probability that components will fail during a mission. While increased reliability can reduce maintenance logistics mass requirements, the rate of mass reduction decreases over time. In addition, reliability growth requires increased test time and cost. This paper assesses trends in test time requirements, cost, and maintenance logistics mass savings as a function of increase in Mean Time Between Failures (MTBF) for some or all of the components in a system. In general, reliability growth results in superlinear growth in test time requirements, exponential growth in cost, and sublinear benefits (in terms of logistics mass saved). These trends indicate that it is unlikely that reliability growth alone will be a cost-effective approach to maintenance logistics mass reduction and risk mitigation for long-endurance missions. This paper discusses these trends as well as other options to reduce logistics mass such as direct reduction of part mass, commonality, or In-Space Manufacturing (ISM). Overall, it is likely that some combination of all available options - including reliability growth - will be required to reduce mass and mitigate risk for future deep space missions.

Novel time-of-flight spectrometer for the analysis of positron annihilation induced Auger electrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hugenschmidt, Christoph; Legl, Stefan; Physik-Department E21, Technische Universitaet Muenchen, James-Franck-Strasse, 85748 Garching

2006-10-15

Positron annihilation induced Auger-electron spectroscopy (PAES) has several advantages over conventional Auger-electron spectroscopy such as extremely high surface sensitivity and outstanding signal-to-noise ratio at the Auger-transition energy. In order to benefit from these prominent features a low-energy positron beam of high intensity is required for surface sensitive PAES studies. In addition, an electron energy analyzer is required, which efficiently detects the Auger electrons with acceptable energy resolution. For this reason a novel time-of-flight (TOF) spectrometer has been developed at the intense positron source NEPOMUC that allows PAES studies within short measurement time. This TOF-PAES setup combines a trochoidal filter andmore » a flight tube in a Faraday cage in order to achieve an improved energy resolution of about 1 eV at high electron energies up to E{approx_equal}1000 eV. The electron flight time is the time between the annihilation radiation at the sample and when the electron hits a microchannel plate detector at the end of the flight tube.« less

Novel time-of-flight spectrometer for the analysis of positron annihilation induced Auger electrons

NASA Astrophysics Data System (ADS)

Hugenschmidt, Christoph; Legl, Stefan

2006-10-01

Positron annihilation induced Auger-electron spectroscopy (PAES) has several advantages over conventional Auger-electron spectroscopy such as extremely high surface sensitivity and outstanding signal-to-noise ratio at the Auger-transition energy. In order to benefit from these prominent features a low-energy positron beam of high intensity is required for surface sensitive PAES studies. In addition, an electron energy analyzer is required, which efficiently detects the Auger electrons with acceptable energy resolution. For this reason a novel time-of-flight (TOF) spectrometer has been developed at the intense positron source NEPOMUC that allows PAES studies within short measurement time. This TOF-PAES setup combines a trochoidal filter and a flight tube in a Faraday cage in order to achieve an improved energy resolution of about 1eV at high electron energies up to E ≈1000eV. The electron flight time is the time between the annihilation radiation at the sample and when the electron hits a microchannel plate detector at the end of the flight tube.

Endometrial ablation: normal appearance and complications.

PubMed

Drylewicz, Monica R; Robinson, Kathryn; Siegel, Cary Lynn

2018-03-14

Global endometrial ablation is a commonly performed, minimally invasive technique aimed at improving/resolving abnormal uterine bleeding and menorrhagia in women. As non-resectoscopic techniques have come into existence, endometrial ablation performance continues to increase due to accessibility and decreased requirements for operating room time and advanced technical training. The increased utilization of this method translates into increased imaging of patients who have undergone the procedure. An understanding of the expected imaging appearances of endometrial ablation using different modalities is important for the abdominal radiologist. In addition, the frequent usage of the technique naturally comes with complications requiring appropriate imaging work-up. We review the expected appearance of the post-endometrial ablated uterus on multiple imaging modalities and demonstrate the more common and rare complications seen in the immediate post-procedural time period and remotely.

Using time-dependent indirect CP asymmetries to measure T and CPT violation in B0-Bbar0 mixing

NASA Astrophysics Data System (ADS)

Karan, Anirban; Nayak, Abinash Kumar; Sinha, Rahul; London, David

2018-06-01

Quantum field theory, which is the basis for all of particle physics, requires that all processes respect CPT invariance. It is therefore of paramount importance to test the validity of CPT conservation. In this Letter, we show that the time-dependent, indirect CP asymmetries involving B decays to a CP eigenstate contain enough information to measure T and CPT violation in B0-Bbar0 mixing, in addition to the standard CP-violating weak phases. Entangled B0Bbar0 states are not required (so that this analysis can be carried out at LHCb, as well as at the B factories), penguin pollution need not be neglected, and the measurements can be made using Bd0 or Bs0 mesons.

Rapid phenotypic antimicrobial susceptibility testing using nanoliter arrays.

PubMed

Avesar, Jonathan; Rosenfeld, Dekel; Truman-Rosentsvit, Marianna; Ben-Arye, Tom; Geffen, Yuval; Bercovici, Moran; Levenberg, Shulamit

2017-07-18

Antibiotic resistance is a major global health concern that requires action across all sectors of society. In particular, to allow conservative and effective use of antibiotics clinical settings require better diagnostic tools that provide rapid determination of antimicrobial susceptibility. We present a method for rapid and scalable antimicrobial susceptibility testing using stationary nanoliter droplet arrays that is capable of delivering results in approximately half the time of conventional methods, allowing its results to be used the same working day. In addition, we present an algorithm for automated data analysis and a multiplexing system promoting practicality and translatability for clinical settings. We test the efficacy of our approach on numerous clinical isolates and demonstrate a 2-d reduction in diagnostic time when testing bacteria isolated directly from urine samples.

Diagravitropism in corn roots

NASA Technical Reports Server (NTRS)

Leopold, A. C.; Wettlaufer, S. H.

1988-01-01

The diagravitropic behavior of Merit corn (Zea mays L.) roots grown in darkness provides an opportunity for comparison of two qualitatively different gravitropic systems. As with positive gravitropism, diagravitropism is shown to require the presence of the root cap, have a similar time course for the onset of curvature, and a similar presentation time. In contrast with positive gravitropism, diagravitropism appears to have a more limited requirement for calcium, for it is insensitive to the elution of calcium by EGTA and insensitive to the subsequent addition of a calcium/EGTA complex. These results are interpreted as indicating that whereas the same sensing system is shared by the two types of gravitropism, separate transductive systems are involved, one for diagravitropism, which is relatively independent of calcium, and one for positive gravitropism, which is markedly dependent on calcium.

Actual Time Required for Dynamic Fluoroscopic Intraoperative Cholangiography

PubMed Central

Whitwam, Paul; Turner, David; Kennedy, Kathy; Hashmi, Syed

2005-01-01

Objectives: This study was undertaken to determine the actual amount of time a dynamic fluoroscopic intraoperative cholangiogram adds to a laparoscopic cholecystectomy. A secondary objective was to define the information gained from this procedure. Methods: A consecutive case study of 52 patients undergoing laparoscopic cholecystectomy was used. Time was recorded from placement of a laparoscopic hemoclip across the cystic duct at its junction with the gallbladder until successful completion of the intraoperative cholangiogram. The mean, median, and range of times for these cases, as well as the results and false-negative rates, were determined. Results: Cholangiography was successfully completed in 96% of patients. The mean time added to laparoscopic cholecystectomy by the addition of dynamic fluoroscopic intraoperative cholangiography was 4.3 minutes. The median time was 3.0 minutes. The times ranged from 2.0 minutes to 16.0 minutes. Choledocholithiasis was present in 15.4% of these patients. The false-positive rate was zero in this study. Conclusions: Dynamic fluoroscopic intraoperative cholangiogram was fast and efficient. The information gained was significant in that 15% of patients proceeded on to laparoscopic common bile duct exploration. We conclude that intraoperative cholangiography should be a routine addition to laparoscopic cholecystectomy. PMID:15984705

Automatic control in planetary exploration in the 1980s. [onboard spacecraft

NASA Technical Reports Server (NTRS)

Moore, J. W.

1973-01-01

Based on an examination of the planetary missions in the 1980s and their related objectives, a broad assessment of the automatic control capabilities required for these missions is presented. The ten outer-planet, terrestrial-planet, and small-body missions considered involve various operations encompassing a complex series of modes including cruise, maneuver, and powered flight control. In addition to routine navigation and attitude control, onboard control is required to point scientific instruments and antennas with respect to the vehicle and to maneuver the spacecraft in time-constrained or hazardous environments. These 1980 missions aimed at exploring new areas of the solar system will be more demanding. New design philosophies and increased performance capabilities will be required to meet the constraints imposed by science requirements and mission-cost effectiveness.

[Role of Institutional Review Boards for multi-centre studies in national health services research - a cross-sectional study of the effort to obtain secondary ethical approvals for the DACAPO study].

PubMed

Blecha, Sebastian; Thomann-Hackner, Kathrin; Brandstetter, Susanne; Dodoo-Schittko, Frank; Seboek, Philipp; Apfelbacher, Christian; Graf, Bernhard M; Bein, Thomas

2015-09-01

Health services research (HSR) is of fundamental importance for the continuous improvement of preventive, diagnostic or therapeutic measures. The conduct of multi-centre HSR studies requires that ethical approval by Institutional review boards (IRB's) is obtained. We documented the effort, the complexity and the man power necessary to obtain secondary ethical approval for a national HSR in Germany ("Surviving the Acute Respiratory Distress Syndrome" [DACAPO-study]). Having obtained a primary ethical approval by the IRB of Regensburg University, the time, correspondence, necessity for amendments, corrections, or additional costs by 34 IRB's for 64 participating study centers was documented. The complete obtainment was found to be time consuming and associated with a high workload and man power. A time span of seven month was needed to receive votes from all IRB's. The median time span was 25,5 days (25 %/75 % percentile 13 and 42 days, respectively). Requirements in terms of corrections or amendments were inhomogeneous and frequent changes were necessary. There were additional fees for secondary votes of 4328,40 €. Total costs for the study center Regensburg were 21.193,40 € (2,6 % of the grant volume). Obtaining all ethical approvals for a multi-centre observational HSR study in Germany is complex and time consuming. Various and inhomogeneous formalities may delay the plan and realization of HSR. A Homogenization and simplification of the procedure of ethics votes should be discussed. © Georg Thieme Verlag KG Stuttgart · New York.

Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation

PubMed Central

Sukenik, Shahar

2012-01-01

It is widely recognized that amyloid formation sensitively responds to conditions set by myriad cellular solutes. These cosolutes include two important classes: macromolecular crowders and compatible osmolytes. We have recently found that addition of macromolecular PEG only slightly affects fibril formation of a model peptide in vitro. Polyol osmolytes, in contrast, lengthen the lag time for aggregation, and lead to larger fibril mass at equilibrium. To further hypothesize on the molecular underpinnings of the disparate effect of the two cosolute classes, we have further analyzed the experiments using an available kinetic mechanism describing fibril aggregation. Model calculations suggest that all cosolutes similarly lengthen the time required for nucleation, possibly due to their excluded volume effect. However, PEGs may in addition promote fibril fragmentation, leading to lag times that are overall almost unvaried. Moreover, polyols effectively slow the monomer-fibril detachment rates, thereby favoring additional fibril formation. Our analysis provides first hints that cosolutes act not only by changing association or dissociation rates, but potentially also by directing the formation of fibrils of varied morphologies with different mechanical properties. Although additional experiments are needed to unambiguously resolve the action of excluded cosolutes on amyloid formation, it is becoming clear that these compounds are important to consider in the search for ways to modulate fibril formation. PMID:22453174

Improving computer security for authentication of users: influence of proactive password restrictions.

PubMed

Proctor, Robert W; Lien, Mei-Ching; Vu, Kim-Phuong L; Schultz, E Eugene; Salvendy, Gavriel

2002-05-01

Entering a username-password combination is a widely used procedure for identification and authentication in computer systems. However, it is a notoriously weak method, in that the passwords adopted by many users are easy to crack. In an attempt to improve security, proactive password checking may be used, in which passwords must meet several criteria to be more resistant to cracking. In two experiments, we examined the influence of proactive password restrictions on the time that it took to generate an acceptable password and to use it subsequently to long in. The required length was a minimum of five characters in Experiment 1 and eight characters in Experiment 2. In both experiments, one condition had only the length restriction, and the other had additional restrictions. The additional restrictions greatly increased the time it took to generate the password but had only a small effect on the time it took to use it subsequently to long in. For the five-character passwords, 75% were cracked when no other restrictions were imposed, and this was reduced to 33% with the additional restrictions. For the eight-character passwords, 17% were cracked with no other restrictions, and 12.5% with restrictions. The results indicate that increasing the minimum character length reduces crackability and increases security, regardless of whether additional restrictions are imposed.

Challenges of Achieving 2012 IECC Air Sealing Requirements in Multifamily Dwellings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klocke, S.; Faakye, O.; Puttagunta, S.

2014-10-01

While previous versions of the International Energy Conservation Code (IECC) have included provisions to improve the air tightness of dwellings, for the first time, the 2012 IECC mandates compliance verification through blower door testing. Simply completing the Air Barrier and Insulation Installation checklist through visual inspection is no longer sufficient by itself. In addition, the 2012 IECC mandates a significantly stricter air sealing requirement. In Climate Zones 3 through 8, air leakage may not exceed 3 ACH50, which is a significant reduction from the 2009 IECC requirement of 7 ACH50. This requirement is for all residential buildings, which includes low-risemore » multifamily dwellings. While this air leakage rate requirement is an important component to achieving an efficient building thermal envelope, currently, the code language doesn't explicitly address differences between single family and multifamily applications. In addition, the 2012 IECC does not provide an option to sample dwellings for larger multifamily buildings, so compliance would have to be verified on every unit. With compliance with the 2012 IECC air leakage requirements on the horizon, several of Consortium for Advanced Residential Building's (CARB’s) multifamily builder partners are evaluating how best to comply with this requirement. Builders are not sure whether it is more practical or beneficial to simply pay for guarded testing or to revise their air sealing strategies to improve compartmentalization to comply with code requirements based on unguarded blower door testing. This report summarizes CARB's research that was conducted to assess the feasibility of meeting the 2012 IECC air leakage requirements in 3 multifamily buildings.« less

Building America Case Study: Challenges of Achieving 2012 IECC Air Sealing Requirements in Multifamily Dwellings, Upstate New York (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2014-11-01

While previous versions of the International Energy Conservation Code (IECC) have included provisions to improve the air tightness of dwellings, for the first time, the 2012 IECC mandates compliance verification through blower door testing. Simply completing the Air Barrier and Insulation Installation checklist through visual inspection is no longer sufficient by itself. In addition, the 2012 IECC mandates a significantly stricter air sealing requirement. In Climate Zones 3 through 8, air leakage may not exceed 3 ACH50, which is a significant reduction from the 2009 IECC requirement of 7 ACH50. This requirement is for all residential buildings, which includes low-risemore » multifamily dwellings. While this air leakage rate requirement is an important component to achieving an efficient building thermal envelope, currently, the code language doesn't explicitly address differences between single family and multifamily applications. In addition, the 2012 IECC does not provide an option to sample dwellings for larger multifamily buildings, so compliance would have to be verified on every unit. With compliance with the 2012 IECC air leakage requirements on the horizon, several of CARB's multifamily builder partners are evaluating how best to comply with this requirement. Builders are not sure whether it is more practical or beneficial to simply pay for guarded testing or to revise their air sealing strategies to improve compartmentalization to comply with code requirements based on unguarded blower door testing. This report summarizes CARB's research that was conducted to assess the feasibility of meeting the 2012 IECC air leakage requirements in 3 multifamily buildings.« less

Challenges of Achieving 2012 IECC Air Sealing Requirements in Multifamily Dwellings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klocke, S.; Faakye, O.; Puttagunta, S.

2014-10-01

​While previous versions of the International Energy Conservation Code (IECC) have included provisions to improve the air tightness of dwellings, for the first time, the 2012 IECC mandates compliance verification through blower door testing. Simply completing the Air Barrier and Insulation Installation checklist through visual inspection is no longer sufficient by itself. In addition, the 2012 IECC mandates a significantly stricter air sealing requirement. In Climate Zones 3 through 8, air leakage may not exceed 3 ACH50, which is a significant reduction from the 2009 IECC requirement of 7 ACH50. This requirement is for all residential buildings, which includes low-risemore » multifamily dwellings. While this air leakage rate requirement is an important component to achieving an efficient building thermal envelope, currently, the code language doesn't explicitly address differences between single family and multifamily applications. In addition, the 2012 IECC does not provide an option to sample dwellings for larger multifamily buildings, so compliance would have to be verified on every unit. With compliance with the 2012 IECC air leakage requirements on the horizon, several of CARB's multifamily builder partners are evaluating how best to comply with this requirement. Builders are not sure whether it is more practical or beneficial to simply pay for guarded testing or to revise their air sealing strategies to improve compartmentalization to comply with code requirements based on unguarded blower door testing. This report summarizes CARB's research that was conducted to assess the feasibility of meeting the 2012 IECC air leakage requirements in 3 multifamily buildings.« less

Approaches and Data Quality for Global Precipitation Estimation

NASA Astrophysics Data System (ADS)

Huffman, G. J.; Bolvin, D. T.; Nelkin, E. J.

2015-12-01

The space and time scales on which precipitation varies are small compared to the satellite coverage that we have, so it is necessary to merge "all" of the available satellite estimates. Differing retrieval capabilities from the various satellites require inter-calibration for the satellite estimates, while "morphing", i.e., Lagrangian time interpolation, is used to lengthen the period over which time interpolation is valid. Additionally, estimates from geostationary-Earth-orbit infrared data are plentiful, but of sufficiently lower quality compared to low-Earth-orbit passive microwave estimates that they are only used when needed. Finally, monthly surface precipitation gauge data can be used to reduce bias and improve patterns of occurrence for monthly satellite data, and short-interval satellite estimates can be improved with a simple scaling such that they sum to the monthly satellite-gauge combination. The presentation will briefly consider some of the design decisions for practical computation of the Global Precipitation Measurement (GPM) mission product Integrated Multi-satellitE Retrievals for GPM (IMERG), then examine design choices that maximize value for end users. For example, data fields are provided in the output file that provide insight into the basis for the estimated precipitation, including error, sensor providing the estimate, precipitation phase (solid/liquid), and intermediate precipitation estimates. Another important initiative is successive computations for the same data date/time at longer latencies as additional data are received, which for IMERG is currently done at 6 hours, 16 hours, and 3 months after observation time. Importantly, users require long records for each latency, which runs counter to the data archiving practices at most archive sites. As well, the assignment of Digital Object Identifiers (DOI's) for near-real-time data sets (at 6 and 16 hours for IMERG) is not a settled issue.

Effect of additives on mineral trioxide aggregate setting reaction product formation.

PubMed

Zapf, Angela M; Chedella, Sharath C V; Berzins, David W

2015-01-01

Mineral trioxide aggregate (MTA) sets via hydration of calcium silicates to yield calcium silicate hydrates and calcium hydroxide (Ca[OH]2). However, a drawback of MTA is its long setting time. Therefore, many additives have been suggested to reduce the setting time. The effect those additives have on setting reaction product formation has been ignored. The objective was to examine the effect additives have on MTA's setting time and setting reaction using differential scanning calorimetry (DSC). MTA powder was prepared with distilled water (control), phosphate buffered saline, 5% calcium chloride (CaCl2), 3% sodium hypochlorite (NaOCl), or lidocaine in a 3:1 mixture and placed in crucibles for DSC evaluation. The setting exothermic reactions were evaluated at 37°C for 8 hours to determine the setting time. Separate samples were stored and evaluated using dynamic DSC scans (37°C→640°C at10°C/min) at 1 day, 1 week, 1 month, and 3 months (n = 9/group/time). Dynamic DSC quantifies the reaction product formed from the amount of heat required to decompose it. Thermographic peaks were integrated to determine enthalpy, which was analyzed with analysis of variance/Tukey test (α = 0.05). Isothermal DSC identified 2 main exothermal peaks occurring at 44 ± 12 and 343 ± 57 minutes for the control. Only the CaCl2 additive was an accelerant, which was observed by a greater exothermic peak at 101 ± 11 minutes, indicating a decreased setting time. The dynamic DSC scans produced an endothermic peak around 450°C-550°C attributed to Ca(OH)2 decomposition. The use of a few additives (NaOCl and lidocaine) resulted in significantly less Ca(OH)2 product formation. DSC was used to discriminate calcium hydroxide formation in MTA mixed with various additives and showed NaOCl and lidocaine are detrimental to MTA reaction product formation, whereas CaCl2 accelerated the reaction. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

40 CFR 63.504 - Additional requirements for performance testing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Additional requirements for performance... Additional requirements for performance testing. (a) Performance testing shall be conducted in accordance.... Sections 63.484 through 63.501 also contain specific testing requirements. (1) Performance tests shall be...

46 CFR 133.07 - Additional equipment and requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Additional equipment and requirements. 133.07 Section 133.07 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.07 Additional equipment and requirements. The OCMI may require an OSV to...

46 CFR 133.07 - Additional equipment and requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Additional equipment and requirements. 133.07 Section 133.07 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.07 Additional equipment and requirements. The OCMI may require an OSV to...

36 CFR 1236.24 - What are the additional requirements for managing unstructured electronic records?

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements for managing unstructured electronic records? 1236.24 Section 1236.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional Requirements for Electronic Records § 1236.24 What are the additional requirements for managing...

36 CFR 1236.24 - What are the additional requirements for managing unstructured electronic records?

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements for managing unstructured electronic records? 1236.24 Section 1236.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional Requirements for Electronic Records § 1236.24 What are the additional requirements for managing...

36 CFR 1236.24 - What are the additional requirements for managing unstructured electronic records?

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements for managing unstructured electronic records? 1236.24 Section 1236.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional Requirements for Electronic Records § 1236.24 What are the additional requirements for managing...

36 CFR 1236.24 - What are the additional requirements for managing unstructured electronic records?

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements for managing unstructured electronic records? 1236.24 Section 1236.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional Requirements for Electronic Records § 1236.24 What are the additional requirements for managing...

33 CFR 155.1125 - Additional response plan requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Additional response plan... Additional Response Plan Requirements for Tankers Loading Cargo at a Facility Permitted Under the Trans-Alaska Pipeline Authorization Act § 155.1125 Additional response plan requirements. (a) The owner or...

33 CFR 155.1125 - Additional response plan requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Additional response plan... Additional Response Plan Requirements for Tankers Loading Cargo at a Facility Permitted Under the Trans-Alaska Pipeline Authorization Act § 155.1125 Additional response plan requirements. (a) The owner or...

33 CFR 155.1125 - Additional response plan requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Additional response plan... Additional Response Plan Requirements for Tankers Loading Cargo at a Facility Permitted Under the Trans-Alaska Pipeline Authorization Act § 155.1125 Additional response plan requirements. (a) The owner or...

42 CFR 417.592 - Additional benefits requirement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Additional benefits requirement. 417.592 Section... HEALTH CARE PREPAYMENT PLANS Medicare Payment: Risk Basis § 417.592 Additional benefits requirement. (a... benefits. Provide its Medicare enrollees with additional benefits in accordance with paragraph (c) of this...

Extracellular space preservation aids the connectomic analysis of neural circuits

PubMed Central

Pallotto, Marta; Watkins, Paul V; Fubara, Boma; Singer, Joshua H; Briggman, Kevin L

2015-01-01

Dense connectomic mapping of neuronal circuits is limited by the time and effort required to analyze 3D electron microscopy (EM) datasets. Algorithms designed to automate image segmentation suffer from substantial error rates and require significant manual error correction. Any improvement in segmentation error rates would therefore directly reduce the time required to analyze 3D EM data. We explored preserving extracellular space (ECS) during chemical tissue fixation to improve the ability to segment neurites and to identify synaptic contacts. ECS preserved tissue is easier to segment using machine learning algorithms, leading to significantly reduced error rates. In addition, we observed that electrical synapses are readily identified in ECS preserved tissue. Finally, we determined that antibodies penetrate deep into ECS preserved tissue with only minimal permeabilization, thereby enabling correlated light microscopy (LM) and EM studies. We conclude that preservation of ECS benefits multiple aspects of the connectomic analysis of neural circuits. DOI: http://dx.doi.org/10.7554/eLife.08206.001 PMID:26650352

Development of polymer nano composite patterns using fused deposition modeling for rapid investment casting process

NASA Astrophysics Data System (ADS)

Vivek, Tiwary; Arunkumar, P.; Deshpande, A. S.; Vinayak, Malik; Kulkarni, R. M.; Asif, Angadi

2018-04-01

Conventional investment casting is one of the oldest and most economical manufacturing techniques to produce intricate and complex part geometries. However, investment casting is considered economical only if the volume of production is large. Design iterations and design optimisations in this technique proves to be very costly due to time and tooling cost for making dies for producing wax patterns. However, with the advent of Additive manufacturing technology, plastic patterns promise a very good potential to replace the wax patterns. This approach can be very useful for low volume production & lab requirements, since the cost and time required to incorporate the changes in the design is very low. This research paper discusses the steps involved for developing polymer nanocomposite filaments and checking its suitability for investment castings. The process parameters of the 3D printer machine are also optimized using the DOE technique to obtain mechanically stronger plastic patterns. The study is done to develop a framework for rapid investment casting for lab as well as industrial requirements.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, E.C.; Killough, S.M.; Rowe, J.C.

The purpose of the Smart Crane Ammunition Transfer System (SCATS) project is to demonstrate robotic/telerobotic controls technology for a mobile articulated crane for missile/munitions handling, delivery, and reload. Missile resupply and reload have been manually intensive operations up to this time. Currently, reload missiles are delivered by truck to the site of the launcher. A crew of four to five personnel reloads the missiles from the truck to the launcher using a hydraulic-powered crane. The missiles are handled carefully for the safety of the missiles and personnel. Numerous steps are required in the reload process and the entire reload operationmore » can take over an hour for some missile systems. Recent US Army directives require the entire operation to be accomplished in a fraction of that time. Current development of SCATS is being based primarily on reloading Patriot missiles. This paper summarizes the current status of the SCATS project at the Oak Ridge National Laboratory (ORNL). Additional information on project background and requirements has been described previously (Bradley, et al., 1995).« less

Genetic transformation of tobacco NT1 cells with Agrobacterium tumefaciens.

PubMed

Mayo, Kristin J; Gonzales, Barbara J; Mason, Hugh S

2006-01-01

This protocol is used to produce stably transformed tobacco (Nicotiana tabacum) NT1 cell lines, using Agrobacterium tumefaciens-mediated DNA delivery of a binary vector containing a gene encoding hepatitis B surface antigen and a gene encoding the kanamycin selection marker. The NT1 cultures, at the appropriate stage of growth, are inoculated with A. tumefaciens containing the binary vector. A 3-day cocultivation period follows, after which the cultures are rinsed and placed on solid selective medium. Transformed colonies ('calli') appear in approximately 4 weeks; they are subcultured until adequate material is obtained for analysis of antigen production. 'Elite' lines are selected based on antigen expression and growth characteristics. The time required for the procedure from preparation of the plant cell materials to callus development is approximately 5 weeks. Growth of selected calli to sufficient quantities for antigen screening may require 4-6 weeks beyond the initial selection. Creation of the plasmid constructs, transformation of the A. tumefaciens line, and ELISA and Bradford assays to assess protein production require additional time.

The use of a personal digital assistant for wireless entry of data into a database via the Internet.

PubMed

Fowler, D L; Hogle, N J; Martini, F; Roh, M S

2002-01-01

Researchers typically record data on a worksheet and at some later time enter it into the database. Wireless data entry and retrieval using a personal digital assistant (PDA) at the site of patient contact can simplify this process and improve efficiency. A surgeon and a nurse coordinator provided the content for the database. The computer programmer created the database, placed the pages of the database on the PDA screen, and researched and installed security measures. Designing the database took 6 months. Meeting Health Insurance Portability and Accountability Act of 1996 (HIPAA) requirements for patient confidentiality, satisfying institutional Information Services requirements, and ensuring connectivity required an additional 8 months before the functional system was complete. It is now possible to achieve wireless entry and retrieval of data using a PDA. Potential advantages include collection and entry of data at the same time, easy entry of data from multiple sites, and retrieval of data at the patient's bedside.

Building flexible real-time systems using the Flex language

NASA Technical Reports Server (NTRS)

Kenny, Kevin B.; Lin, Kwei-Jay

1991-01-01

The design and implementation of a real-time programming language called Flex, which is a derivative of C++, are presented. It is shown how different types of timing requirements might be expressed and enforced in Flex, how they might be fulfilled in a flexible way using different program models, and how the programming environment can help in making binding and scheduling decisions. The timing constraint primitives in Flex are easy to use yet powerful enough to define both independent and relative timing constraints. Program models like imprecise computation and performance polymorphism can carry out flexible real-time programs. In addition, programmers can use a performance measurement tool that produces statistically correct timing models to predict the expected execution time of a program and to help make binding decisions. A real-time programming environment is also presented.

7 CFR 1780.44 - Actions prior to loan or grant closing or start of construction, whichever occurs first.

Code of Federal Regulations, 2010 CFR

2010-01-01

... received that all signed users may not connect to the system, there will be such additional investigation made as deemed necessary to determine the number of users who will connect to the system. (c) Initial... prior to the required deposit time shall be appropriately accounted for. (e) Excess RUS loan and grant...

Integrating Popular Web Applications in Classroom Learning Environments and Its Effects on Teaching, Student Learning Motivation and Performance

ERIC Educational Resources Information Center

Lin, Yen-Ting; Jou, Min

2013-01-01

Advancements in information and communication technology (ICT) allowed several tools and systems to be proposed for improving classroom experiences to both instructors and students. However, most of these tools were brand-new and stand-alone programs that require users to invest additional time and effort to become familiar with their use. This…

Homemade Powerpoint Games: Game Design Pedagogy Aligned to the TPACK Framework

ERIC Educational Resources Information Center

Siko, Jason P.; Barbour, Michael K.

2012-01-01

While researchers are examining the role of playing games to learn, others are looking at using game design as an instructional tool. However, game-design software may require additional time to train both teachers and students. In this article, the authors discuss the use of Microsoft PowerPoint as a tool for game-design instruction and the…

A Comparative Study on Electronic versus Traditional Data Collection in a Special Education Setting

ERIC Educational Resources Information Center

Ruf, Hernan Dennis

2012-01-01

The purpose of the current study was to determine the efficiency of an electronic data collection method compared to a traditional paper-based method in the educational field, in terms of the accuracy of data collected and the time required to do it. In addition, data were collected to assess users' preference and system usability. The study…

User Data Package (UDP) for Packaged Cogeneration Systems (PCS)

DTIC Science & Technology

1990-05-01

Standards for PURPA Compliance ............ ...................... 10 1.3 Selected Commercial, Institutional, and Multi-unit Technically Feasible...percent. The Federal Energy Regulatory Commission (FERC), in accordance with Section 201 of the Public Utility Regulatory Policies Act ( PURPA ) of 1978...percent of the time the engine was running, or if 57 percent of the recovered engine heat were stored. Additional requirements for PURPA efficiency that

Creating Thoughtful Salespeople: Experiential Learning to Improve Critical Thinking Skills in Traditional and Online Sales Education

ERIC Educational Resources Information Center

Alvarez, Cecilia M. O.; Taylor, Kimberly A.; Rauseo, Nancy A.

2015-01-01

Most undergraduate marketing majors will spend at least some time in a sales role, and employers are requiring greater professionalism and more varied skill sets from their sales hires. In addition, there is an increasing demand for online and higher order learning in sales education. In response, this article proposes that sales courses using…

Form reconciles meds, but doctor buy-in difficult.

PubMed

2006-02-01

One ED has developed a medication reconciliation form to meet the National Patient Safety Goal of reconciling medications across the continuum of care. The form does require additional staff time to complete. Staff and physicians need training so they understand the importance of meeting the safety goal. Physicians may resist giving orders on previously prescribed meds and may see the form as redundant.

29 CFR 550.1 - “Talent fees” as used in section 7(e)(3)(c) of the Fair Labor Standards Act, as amended.

Code of Federal Regulations, 2014 CFR

2014-07-01

... performer on a particular commercial program or a particular series of commercial programs (including... particular series of sustaining programs; (b) In pursuance of an applicable employment agreement or... requiring additional compensation as a result of the time worked on the program if the parties agree in...

75 FR 72944 - Third Party Testing for Certain Children's Products; Mattresses, Mattress Pads, and/or Mattress...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... Standard prescribes a full-scale test using a pair of T-shaped gas burners designed to represent burning... Group sought an additional one year for manufacturers to comply with the third party testing requirement... accredited by an ILAC-MRA member at the time of the test. For firewalled conformity assessment bodies, the...

The Slippery Slope of Air Force Downsizing: A Strategy Connection

DTIC Science & Technology

2013-02-14

as the reductions continue. As an example, commanders and their Airmen are responsible for being administration, personnel, finance, communciations ... computer efficient because the expertise in their units or base has been reduced, eliminated or consolidated. This impacts the time and resources...are the areas that require additional research. • Issue: Other functional issues (Logistics, Finance, Contracting, Communications/ computers , Nuclear

5 CFR 2634.201 - General requirements, filing dates, and extensions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... report. In addition, he must file a new entrant report the first time he serves more than 60 days in a calendar year in the position, in accordance with § 2634.201(b) and § 2634.204(c)(1). (b) New entrants. (1... prior to assuming such position, left another position or office for which a public financial disclosure...

5 CFR 2634.201 - General requirements, filing dates, and extensions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... report. In addition, he must file a new entrant report the first time he serves more than 60 days in a calendar year in the position, in accordance with § 2634.201(b) and § 2634.204(c)(1). (b) New entrants. (1... prior to assuming such position, left another position or office for which a public financial disclosure...

One-step pretreatment of yellow poplar biomass using peracetic acid to enhance enzymatic digestibility.

PubMed

Lee, Hyeong Rae; Kazlauskas, Romas J; Park, Tai Hyun

2017-09-22

Pretreatment of biomass with dilute acid requires high temperatures of >160 °C to remove xylan and does not remove lignin. Here we report that the addition of peracetic acid, a strong oxidant, to mild dilute acid pretreatment reduces the temperature requirement to only 120 °C. Pretreatment of yellow poplar with peracetic acid (300 mM, 2.3 wt%) and dilute sulfuric acid (100 mM, 1.0 wt%) at 120 °C for 5 min removed 85.7% of the xylan and 90.4% of the lignin leaving a solid consisting of 75.6% glucan, 6.0% xylan and 4.7% lignin. Low enzyme loadings of 5 FPU/g glucan and 10 pNPGU/g glucan converted this solid to glucose with an 84.0% yield. This amount of glucose was 2.5 times higher than with dilute acid-pretreated solid and 13.8 times higher than with untreated yellow poplar. Thus, the addition of peracetic acid, easily generated from acetic acid and hydrogen peroxide, dramatically increases the effectiveness of dilute acid pretreatment of biomass.

A high-current rail-type gas switch with preionization by an additional corona discharge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antipov, E. I.; Belozerov, O. S.; Krastelev, E. G., E-mail: ekrastelev@yandex.ru

The characteristics of a high-current rail-type gas switch with preionization of the gas (air) in a spark gap by an additional corona discharge are investigated. The experiments were performed in a voltage range of 10–45 kV using a two-electrode switch consisting of two cylindrical electrodes with a diameter of 22 mm and a length of 100 mm and a set of laterally located corona-discharge needles. The requirements for the position and size of the needles are defined for which a corona discharge is ignited before a breakdown of the main gap and does not change to a sparking form, andmore » the entire length of the rail electrodes is efficiently used. The fulfillment of these requirements ensures stable operation of the switch with a small variation of the pulse breakdown voltage, which is not more than 1% for a fixed voltage-pulse rise time in the range from 150 ns to 3.5 μs. A short delay time of the switch breakdown makes it possible to control the two-electrode switch by an overvoltage pulse of nanosecond duration.« less

SU-E-T-97: An Analysis of Knowledge Based Planning for Stereotactic Body Radiation Therapy of the Spine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foy, J; Marsh, R; Owen, D

2015-06-15

Purpose: Creating high quality SBRT treatment plans for the spine is often tedious and time consuming. In addition, the quality of treatment plans can vary greatly between treatment facilities due to inconsistencies in planning methods. This study investigates the performance of knowledge-based planning (KBP) for spine SBRT. Methods: Treatment plans were created for 28 spine SBRT patients. Each case was planned to meet strict dose objectives and guidelines. After physician and physicist approval, the plans were added to a custom model in a KBP system (RapidPlan, Varian Eclipse v13.5). The model was then trained to be able to predict estimatedmore » DVHs and provide starting objective functions for future patients based on both generated and manual objectives. To validate the model, ten additional spine SBRT cases were planned manually as well as using the model objectives. Plans were compared based on planning time and quality (ability to meet the plan objectives, including dose metrics and conformity). Results: The average dose to the spinal cord and the cord PRV differed between the validation and control plans by <0.25% demonstrating iso-toxicity. Six out of 10 validation plans met all dose objectives without the need for modifications, and overall, target dose coverage was increased by about 4.8%. If the validation plans did not meet the dose requirements initially, only 1–2 iterations of modifying the planning parameters were required before an acceptable plan was achieved. While manually created plans usually required 30 minutes to 3 hours to create, KBP can be used to create similar quality plans in 15–20 minutes. Conclusion: KBP for spinal tumors has shown to greatly decrease the amount of time required to achieve high quality treatment plans with minimal human intervention and could feasibly be used to standardize plan quality between institutions. Supported by Varian Medical Systems.« less

Clinical Utility of the Modified Segmental Boost Technique for Treatment of the Pelvis and Inguinal Nodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moran, M.S., E-mail: meena.moran@yale.ed; Yale New Haven Hospital, New Haven, Connecticut and William W. Backus Hospital, Norwich, Connecticut; Castrucci, W.A.

2010-03-15

Purpose: Low-lying pelvic malignancies often require simultaneous radiation to pelvis and inguinal nodes. We previously reported improved homogeneity with the modified segmental boost technique (MSBT) compared to that with traditional methods, using phantom models. Here we report our institutional clinical experience with MSBT. Methods and Materials: MSBT patients from May 2001 to March 2007 were evaluated. Parameters analyzed included isocenter/multileaf collimation shifts, time per fraction (four fields), monitor units (MU)/fraction, femoral doses, maximal dose relative to body mass index, and inguinal node depth. In addition, a dosimetric comparison of the MSBT versus intensity modulated radiation therapy (IMRT) was conducted. Results:more » Of the 37 MSBT patients identified, 32 were evaluable. Port film adjustments were required in 6% of films. Median values for each analyzed parameter were as follows: MU/fraction, 298 (range, 226-348); delivery time, 4 minutes; inguinal depth, 4.5 cm; volume receiving 45 Gy (V45), 7%; V27.5, 87%; body mass index, 25 (range, 16.0-33.8). Inguinal dose was 100% in all cases; in-field inhomogeneity ranged from 111% to 118%. IMRT resulted in significantly decreased dose to normal tissue but required more time for treatment planning and a higher number of MUs (1,184 vs. 313 MU). Conclusions: In our clinical experience, the mono-isocentric MSBT provides a high degree of accuracy, improved homogeneity compared with traditional techniques, ease of simulation, treatment planning, treatment delivery, and acceptable femoral doses for pelvic/inguinal radiation fields requiring 45 to 50.4 Gy. In addition, the MSBT delivers a relatively uniform dose distribution throughout the treatment volume, despite varying body habitus. Clinical scenarios for the use of MSBT vs. intensity-modulated radiation therapy are discussed. To our knowledge, this is the first study reporting the utility of MSBT in the clinical setting.« less

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Code of Federal Regulations, 2011 CFR

2011-10-01

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46 CFR 111.105-39 - Additional requirements for vessels carrying vehicles with fuel in their tanks.

Code of Federal Regulations, 2012 CFR

2012-10-01

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Code of Federal Regulations, 2014 CFR

2014-07-01

... identification requirements for diesel fuel additives? 80.521 Section 80.521 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES... requirements for diesel fuel additives? (a) Except as provided in paragraph (b) of this section, any diesel...

40 CFR 80.521 - What are the standards and identification requirements for diesel fuel additives?

Code of Federal Regulations, 2011 CFR

2011-07-01

... identification requirements for diesel fuel additives? 80.521 Section 80.521 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES... requirements for diesel fuel additives? (a) Except as provided in paragraph (b) of this section, any diesel...

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Code of Federal Regulations, 2013 CFR

2013-07-01

... identification requirements for diesel fuel additives? 80.521 Section 80.521 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES... requirements for diesel fuel additives? (a) Except as provided in paragraph (b) of this section, any diesel...

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Code of Federal Regulations, 2010 CFR

2010-07-01

... identification requirements for diesel fuel additives? 80.521 Section 80.521 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES... requirements for diesel fuel additives? (a) Except as provided in paragraph (b) of this section, any diesel...

40 CFR 80.521 - What are the standards and identification requirements for diesel fuel additives?

Code of Federal Regulations, 2012 CFR

2012-07-01

... identification requirements for diesel fuel additives? 80.521 Section 80.521 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES... requirements for diesel fuel additives? (a) Except as provided in paragraph (b) of this section, any diesel...