Science.gov

Sample records for address basic science

  1. A prescription that addresses the decline of basic science education in medical school.

    PubMed

    Miller, Daniel; Thornton, Christina S; Keough, Michael B; Roberts, Jodie I; Yipp, Bryan; Hollenberg, Morley; Bau, Jason T; Peplowski, Michael A; Beck, Paul L

    2014-10-04

    Over 30 years ago a cry rang out through the proverbial halls of academia; "The clinician scientist is an endangered species." These prophetic words have been reverberated in the ears of every specialty and every general medical organization in deafening tones. Why is the role of the clinician scientist or clinician investigator so important that this phrase has been repeated subsequently in medical and educational journals? Simply put, the clinician scientist bridges the ravine between the ever-growing mountain of scientific knowledge and the demanding patient centered clinical care. Here, we describe the current educational model established by the University of Calgary, Leaders in Medicine Program. Our program seeks to train future physicians and clinician scientists by incorporating training in basic science, translational and clinical research with clinical and medical education in a longitudinal program to students of traditional MD/PhD, MD/MSc or MD/MBA stream as well as interested Doctor of Medicine students.

  2. Basic Science.

    ERIC Educational Resources Information Center

    Mercer County Community Coll., Trenton, NJ.

    Instructional materials are provided for a course that covers basic concepts of physics and chemistry. Designed for use in a workplace literacy project developed by Mercer County Community College (New Jersey) and its partners, the course describes applications of these concepts to real-life situations, with an emphasis on applications of…

  3. A model for integrating clinical care and basic science research, and pitfalls of performing complex research projects for addressing a clinical challenge.

    PubMed

    Steck, R; Epari, D R; Schuetz, M A

    2010-07-01

    The collaboration of clinicians with basic science researchers is crucial for addressing clinically relevant research questions. In order to initiate such mutually beneficial relationships, we propose a model where early career clinicians spend a designated time embedded in established basic science research groups, in order to pursue a postgraduate qualification. During this time, clinicians become integral members of the research team, fostering long term relationships and opening up opportunities for continuing collaboration. However, for these collaborations to be successful there are pitfalls to be avoided. Limited time and funding can lead to attempts to answer clinical challenges with highly complex research projects characterised by a large number of "clinical" factors being introduced in the hope that the research outcomes will be more clinically relevant. As a result, the complexity of such studies and variability of its outcomes may lead to difficulties in drawing scientifically justified and clinically useful conclusions. Consequently, we stress that it is the basic science researcher and the clinician's obligation to be mindful of the limitations and challenges of such multi-factorial research projects. A systematic step-by-step approach to address clinical research questions with limited, but highly targeted and well defined research projects provides the solid foundation which may lead to the development of a longer term research program for addressing more challenging clinical problems. Ultimately, we believe that it is such models, encouraging the vital collaboration between clinicians and researchers for the work on targeted, well defined research projects, which will result in answers to the important clinical challenges of today.

  4. Basic Science Training Program.

    ERIC Educational Resources Information Center

    Brummel, Clete

    These six learning modules were developed for Lake Michigan College's Basic Science Training Program, a workshop to develop good study skills while reviewing basic science. The first module, which was designed to provide students with the necessary skills to study efficiently, covers the following topics: time management; an overview of a study…

  5. Basic Science and The NIH

    PubMed Central

    Varmus, Harold

    1994-01-01

    The following is an edited version of the Keynote Speech delivered at the Annual Meeting of the American Society for Cell Biology by Harold Varmus, Director of the National Institutes of Health. The address, entitled Basic Science and the NIH, was given at the opening of the meeting in New Orleans on December 11, 1993. It was Varmus' first public policy talk as NIH Director. PMID:8049519

  6. Basic sciences: an alternative career?

    PubMed

    Khatri, R

    2013-01-01

    Career selection is a crucial and a complex process which is also true for the medical profession. In the context of our country, due to the limited opportunity and proper guidance, migration of medical graduates to foreign countries is increasing. Though, clinical subjects have a huge attraction, basic science field has failed to impress our medical graduates. In current scenario, basic science field seems to be a dumping site for the incompetent as the candidates who have failed trying their luck elsewhere stumble upon basic science careers though it is not true for all. Moreover, a very few medical graduates are interested in developing their career as a basic scientist. Therefore, to motivate today's young medical graduates, there is a need of a good mentor along with a proper career guidance which can help them to understand the basic science field as an alternative career.

  7. Basic Physics Questions Addressed by Astrophysics

    NASA Technical Reports Server (NTRS)

    Mather, John C.

    2009-01-01

    Dark matter, dark energy, the Big Bang, testing relativity -- all are physics questions accessible to astrophysicists -- but all require new equipment. As Harwit's "Cosmic Discovery" pointed out, almost all great surprises in astronomy came from new equipment or new uses of equipment designed for other purposes, and many of those had military applications. I will outline prospects for new equipment and discuss how that equipment can be developed and built. Bigger and lighter mirrors, wavefront sensing and control, new detector technology, cryogenics -- each has its own social network, its own special possibilities, and its own funding sources outside science. I will discuss some examples drawn from real-life experience with the James Webb Space Telescope, a telescope that was said to have a "giggle factor" when it was proposed in 1995. Now each of the 10 major technologies has been brought to maturity, flight hardware is being built, and launch is planned for 2014. As an instrument builder all my life, I will speculate a little on what may be within our reach over the next few decades.

  8. Basic science of osteoarthritis.

    PubMed

    Cucchiarini, Magali; de Girolamo, Laura; Filardo, Giuseppe; Oliveira, J Miguel; Orth, Patrick; Pape, Dietrich; Reboul, Pascal

    2016-12-01

    Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large population worldwide and for which there is no definitive cure. This review provides critical insights into the basic knowledge on OA that may lead to innovative end efficient new therapeutic regimens. While degradation of the articular cartilage is the hallmark of OA, with altered interactions between chondrocytes and compounds of the extracellular matrix, the subchondral bone has been also described as a key component of the disease, involving specific pathomechanisms controlling its initiation and progression. The identification of such events (and thus of possible targets for therapy) has been made possible by the availability of a number of animal models that aim at reproducing the human pathology, in particular large models of high tibial osteotomy (HTO). From a therapeutic point of view, mesenchymal stem cells (MSCs) represent a promising option for the treatment of OA and may be used concomitantly with functional substitutes integrating scaffolds and drugs/growth factors in tissue engineering setups. Altogether, these advances in the fundamental and experimental knowledge on OA may allow for the generation of improved, adapted therapeutic regimens to treat human OA.

  9. Basic science of pain.

    PubMed

    DeLeo, Joyce A

    2006-04-01

    The origin of the theory that the transmission of pain is through a single channel from the skin to the brain can be traced to the philosopher and scientist René Descartes. This simplified scheme of the reflex was the beginning of the development of the modern doctrine of reflexes. Unfortunately, Descartes' reflex theory directed both the study and treatment of pain for more than 330 years. It is still described in physiology and neuroscience textbooks as fact rather than theory. The gate control theory proposed by Melzack and Wall in 1965 rejuvenated the field of pain study and led to further investigation into the phenomena of spinal sensitization and central nervous system plasticity, which are the potential pathophysiologic correlates of chronic pain. The processing of pain takes place in an integrated matrix throughout the neuroaxis and occurs on at least three levels-at peripheral, spinal, and supraspinal sites. Basic strategies of pain control monopolize on this concept of integration by attenuation or blockade of pain through intervention at the periphery, by activation of inhibitory processes that gate pain at the spinal cord and brain, and by interference with the perception of pain. This article discusses each level of pain modulation and reviews the mechanisms of action of opioids and potential new analgesics. A brief description of animal models frames a discussion about recent advances regarding the role of glial cells and central nervous system neuroimmune activation and innate immunity in the etiology of chronic pain states. Future investigation into the discovery and development of novel, nonopioid drug therapy may provide needed options for the millions of patients who suffer from chronic pain syndromes, including syndromes in which the pain originates from peripheral nerve, nerve root, spinal cord, bone, muscle, and disc.

  10. Office of Basic Energy Sciences

    NASA Astrophysics Data System (ADS)

    1991-09-01

    Basic research is an important investment in the future and will help the U.S. maintain and enhance its economic strength. The U.S. Department of Energy Office of Basic Energy Sciences (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals (energy self-sufficiency, improved health and quality of life for all, economic growth, national security) depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions. The program has two distinct interrelated parts: research and facilities operations and development. In the pursuit of forefront research results, BES designs, builds and operates certain large, complex advanced scientific facilities such as neutron sources and synchrotron radiation sources. These facilities not only provide BES with unique instruments, but these instruments are also made available to all qualified users, even those not supported by BES. Thus, the facilities actually leverage a great deal more research from the national effort. The BES program conducts basic research that will most likely help the Nation's long-term energy goals. BES implements a broad strategy for conducting basic research and contributes strongly towards national energy goals and to national goals of maintaining and enhancing scientific leadership, technological innovation, and economic strength.

  11. CROI 2016: Basic Science Review.

    PubMed

    Stevenson, Mario

    2016-01-01

    The 2016 Conference on Retroviruses and Opportunistic Infections continued to maintain balance in the representation of different areas of research related to HIV/AIDS. The basic science category encompasses research on viral reservoirs and HIV cure, on cellular factors regulating the interplay between virus and host, and on factors that influence viral pathogenicity. Basic research on factors that influence the interaction between the virus and the host cell continues to unearth surprises with the identification of a new host antiviral factor. Further, research into the mechanisms of viral persistence reveals that there is much to learn about how HIV-1 is able to persist in the face of antiviral suppression.

  12. Basic sciences agonize in Turkey!

    NASA Astrophysics Data System (ADS)

    Akdemir, Fatma; Araz, Asli; Akman, Ferdi; Durak, Rıdvan

    2016-04-01

    In this study, changes from past to present in the departments of physics, chemistry, biology and mathematics, which are considered as the basic sciences in Turkey, are shown. The importance of basic science for the country emphasized and the status of our country was discussed with a critical perspective. The number of academic staff, the number of students, opened quotas according to years for these four departments at universities were calculated and analysis of the resulting changes were made. In examined graphics changes to these four departments were similar. Especially a significant change was observed in the physics department. Lack of jobs employing young people who have graduated from basic science is also an issue that must be discussed. There are also qualitative results of this study that we have discussed as quantitative. Psychological problems caused by unemployment have become a disease among young people. This study was focused on more quantitative results. We have tried to explain the causes of obtained results and propose solutions.

  13. CROI 2014: Basic science review.

    PubMed

    Stevenson, Mario

    2014-05-01

    In the HIV basic science categories of the 2014 Conference on Retroviruses and Opportunistic Infections, research examining obstacles to viral eradication continued to be a major component. This research encompassed areas of activity from the identification of where virus resides in individuals on suppressive antiretroviral therapy to studies aimed at eliminating long-lived viral reservoirs that persist in the face of therapy. In the area of antiviral restrictions, a number of presentations highlighted the ability of host factors to profoundly shape the interplay between virus and host and, in particular, how innate immune response opposes viral infection through the induction of antiviral restrictions.

  14. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, Hans; Balogh, Werner

    2014-05-01

    The basic space science initiative was a long-term effort for the development of astronomy and space science through regional and international cooperation in this field on a worldwide basis, particularly in developing nations. Basic space science workshops were co-sponsored and co-organized by ESA, JAXA, and NASA. A series of workshops on basic space science was held from 1991 to 2004 (India 1991, Costa Rica and Colombia 1992, Nigeria 1993, Egypt 1994, Sri Lanka 1995, Germany 1996, Honduras 1997, Jordan 1999, France 2000, Mauritius 2001, Argentina 2002, and China 2004; http://neutrino.aquaphoenix.com/un-esa/) and addressed the status of astronomy in Asia and the Pacific, Latin America and the Caribbean, Africa, and Western Asia. Through the lead of the National Astronomical Observatory Japan, astronomical telescope facilities were inaugurated in seven developing nations and planetariums were established in twenty developing nations based on the donation of respective equipment by Japan.Pursuant to resolutions of the Committee on the Peaceful Uses of Outer Space of the United Nations (COPUOS) and its Scientific and Technical Subcommittee, since 2005, these workshops focused on the preparations for and the follow-ups to the International Heliophysical Year 2007 (UAE 2005, India 2006, Japan 2007, Bulgaria 2008, South Korea 2009; www.unoosa.org/oosa/SAP/bss/ihy2007/index.html). IHY's legacy is the current operation of 16 worldwide instrument arrays with more than 1000 instruments recording data on solar-terrestrial interaction from coronal mass ejections to variations of the total electron content in the ionosphere (http://iswisecretariat.org/). Instruments are provided to hosting institutions by entities of Armenia, Brazil, France, Israel, Japan, Switzerland, and the United States. Starting in 2010, the workshops focused on the International Space Weather Initiative (ISWI) as mandated in a three-year-work plan as part of the deliberations of COPUOS. Workshops on ISWI

  15. CROI 2013: Basic science review.

    PubMed

    Stevenson, Mario

    2013-01-01

    The 20th Conference on Retroviruses and Opportunistic Infections was held in Atlanta, Georgia, and featured strong coverage in several basic science categories. Presentations on viral reservoir and cure research covered a variety of topics, including approaches to gauge viral reservoir size in patients on suppressive antiretroviral therapy, approaches to reactivate latently infected cells, and the role of residual replication in viral persistence under antiretroviral therapy. Research on viral restriction factors remains a strong feature of the conference, and presentations on the impact of viral restrictions on the establishment of viral reservoirs, as well as strategies that harness the antiviral potential of cellular restrictions, generated a lot of interest. Several studies on the nature of proviral latency left us with the sobering message that elimination of the latent viral pool is going to be an even greater challenge than previously suspected.

  16. CROI 2015: Basic Science Review.

    PubMed

    Stevenson, Mario

    2015-01-01

    The 2015 Conference on Retroviruses and Opportunistic Infections (CROI) represents a forum that encompasses all facets of research on HIV/AIDS and its complications. CROI is a valuable venue for scientific and public health researchers, clinicians, policy makers, and community representatives to be updated on the latest advances in their specific areas of interest and beyond. CROI 2015 continued to surprise. New insights into the viral reservoirs that persist in the face of antiretroviral therapy were prominently featured, as were therapeutic approaches aimed at curtailing and eliminating persistent viral reservoirs in HIV-infected individuals. Basic science is providing surrogates that could be valuable in how viral reservoirs are measured and, ultimately, in how to gauge if they are being effectively eliminated.

  17. Basic space sciences in Africa

    NASA Astrophysics Data System (ADS)

    Abiodun, Adigun Ade; Odingo, Richard S.

    Through space applications, a number of social and economic programmes in education, communications, agro-climatology, weather forecasting and remote sensing are being realized within the African continent. Regional and international organizations and agencies such as the African Remote Sensing Council, the Pan-African Telecommunication Union and the United Nations system have been instrumental in making Africa conscious of the impact and implications of space science and technology on its peoples. The above notwithstanding, discernible interests in space research, to date, in Africa, have been limited to the work on the solar system and on interplanetary matters including satellite tracking, and to the joint African-Indian proposal for the establishment of an International Institute for Space Sciences and Electronics (INISSE) and the construction, in Kenya, of a Giant Equatorial Radio Telescope (GERT). During this ``Transport and Communications Decade in Africa,'' Africa's basic space research efforts would need to initially focus on the appropriateness, modification and adaptation of existing technologies for African conditions with a view to providing economic, reliable and functional services for the continent. These should include elements of electronics, communications, structural and tooling industries, and upper-atmosphere research. The experience of and collaborative work with India, Brazil and Argentina, as well as the roles of African scientists, are examined.

  18. Basic Energy Sciences Program Update

    SciTech Connect

    None, None

    2016-01-04

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) supports fundamental research to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels to provide the foundations for new energy technologies and to support DOE missions in energy, environment, and national security. The research disciplines covered by BES—condensed matter and materials physics, chemistry, geosciences, and aspects of physical biosciences— are those that discover new materials and design new chemical processes. These disciplines touch virtually every aspect of energy resources, production, conversion, transmission, storage, efficiency, and waste mitigation. BES also plans, constructs, and operates world-class scientific user facilities that provide outstanding capabilities for imaging and spectroscopy, characterizing materials of all kinds ranging from hard metals to fragile biological samples, and studying the chemical transformation of matter. These facilities are used to correlate the microscopic structure of materials with their macroscopic properties and to study chemical processes. Such experiments provide critical insights to electronic, atomic, and molecular configurations, often at ultrasmall length and ultrafast time scales.

  19. Addressing the Public About Science and Religion

    NASA Astrophysics Data System (ADS)

    Peshkin, Murray

    2010-03-01

    Attacks on the integrity of science teaching in our public schools have recently become increasingly threatening. Geology and Darwinian evolution are the primary targets and cosmology is at risk. Up to now, the Supreme Court has excluded teachings based on religion from public schools for constitutional, not scientific, reasons. But now the incumbent Supreme Court seem less committed to strict separation of church and state than were their predecessors, and federal courts are beginning to judge the science itself. In this situation, we need to create a climate of public opinion favorable to the protection of good science by explaining the issues both to students and to others. I have been trying to do that by addressing audiences such as church groups, other community groups, and high school and college classes. I do not seek to convert committed anti-evolutionists. I am trying to inform the reasonable majority who do not really know what science is and does, or what a theory is and how we know when it's right, or why we tell them that all knowledge is provisional but still insist that we are teaching the right science. Many have been advised by their religious teachers that there is no conflict between science and their religious beliefs but do not see how that can be. I try to explain how they are disjoint discussions. I also discuss the likely consequences for our country if we degrade the teaching of science in the public schools. My audiences have generally been receptive. Here I will relate some lessons I have learned from my experience with such talks. Without doubt, the most important lesson is that most Americans have religious beliefs that are important to them and are willing to consider what I say only because they know I respect their beliefs. This work was partially supported by the U.S. Dept. of Energy, Office of Nuclear Physics, under contract DE-AC02-06CH11357.

  20. Addressing Science Use Cases with HELIO

    NASA Astrophysics Data System (ADS)

    Bentley, R. D.; Aboudarham, J.; Csillaghy, A.; Jacquey, C.; Hapgood, M. A.; Messerotti, M.; Gallagher, P.; Bocchialini, K.; Hurlburt, N. E.; Roberts, D.; Sanchez Duarte, L.

    2009-12-01

    The Heliophysics Integrated Observatory (HELIO) is a new VO project funded under the EC's Seventh Framework Programme (FP7). It includes thirteen partners scattered over six countries and is led by University College London. HELIO is designed to support the heliophysics community and is based on a Service Oriented Architecture. The services developed by and integrated into HELIO can be used to address a wide range of science problems; they can be used individually or as part of a work-flow driven search engine that can use a propagation (or other) model to help locate obervations that describe interesting phenomena. We will describe and discuss how the components of HELIO could be used to address science use cases, particularly how a user can adapt the work flow to their own science interests. Networking is one of the three Activities of the HELIO Integrated Infrastructure Initiatives (I3) project. Within this activity we plan to involve the community in all aspects of the design and testing of the HELIO system, including determining which data and metadata should be included, how the quality and content of metadata can be included, etc. We are investigating ways of making HELIO "domain-aware" so that researchers who are specialists in one of the communities that constitute heliophysics can easily identify, access and use data they need from the other communities. We will discuss how the community can help us develop this capability.

  1. Basic Energy Sciences FY 2012 Research Summaries

    SciTech Connect

    2012-01-01

    This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  2. Basic Energy Sciences FY 2011 Research Summaries

    SciTech Connect

    2011-01-01

    This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  3. Basic Energy Sciences FY 2014 Research Summaries

    SciTech Connect

    2014-01-01

    This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  4. Clinical Science-linking basic science to disease mechanisms.

    PubMed

    Touyz, Rhian M

    2017-04-01

    For more than 50 years, Clinical Science has been at the interface linking basic science to disease mechanisms. Here, Rhian Touyz, the Editor-in-Chief, describes the journal, its aims and scope, and recent developments.

  5. Preparing Science Teachers to Address Contentious and Sensitive Science Topics

    ERIC Educational Resources Information Center

    Ado, Gustave

    2015-01-01

    Purpose: Despite high HIV prevalence rates in Ivory Coast, the formal K-12 curriculum was not developed to address HIV/AIDS information completely for many African students. The purpose of this study was to identify factors that influenced Ivorian teachers' teaching of the HIV/AIDS curriculum in middle school science curricula in nine middle…

  6. Basic Principles of Animal Science. Reprinted.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    The reference book is designed to fulfill the need for organized subject matter dealing with basic principles of animal science to be incorporated into the high school agriculture curriculum. The material presented is scientific knowledge basic to livestock production. Five units contain specific information on the following topics: anatomy and…

  7. Radiological Dispersion Devices and Basic Radiation Science

    ERIC Educational Resources Information Center

    Bevelacqua, Joseph John

    2010-01-01

    Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous…

  8. USGS Science: Addressing Our Nation's Challenges

    USGS Publications Warehouse

    Larson, Tania M.

    2009-01-01

    With 6.6 billion people already living on Earth, and that number increasing every day, human influence on our planet is ever more apparent. Changes to the natural world combined with increasing human demands threaten our health and safety, our national security, our economy, and our quality of life. As a planet and a Nation, we face unprecedented challenges: loss of critical and unique ecosystems, the effects of climate change, increasing demand for limited energy and mineral resources, increasing vulnerability to natural hazards, the effects of emerging diseases on wildlife and human health, and growing needs for clean water. The time to respond to these challenges is now, but policymakers and decisionmakers face difficult choices. With competing priorities to balance, and potentially serious - perhaps irreversible - consequences at stake, our leaders need reliable scientific information to guide their decisions. As the Nation's earth and natural science agency, the USGS monitors and conducts scientific research on natural hazards and resources and how these elements and human activities influence our environment. Because the challenges we face are complex, the science needed to better understand and deal with these challenges must reflect the complex interplay among natural and human systems. With world-class expertise in biology, geology, geography, hydrology, geospatial information, and remote sensing, the USGS is uniquely capable of conducting the comprehensive scientific research needed to better understand the interdependent interactions of Earth's systems. Every day, the USGS helps decisionmakers to minimize loss of life and property, manage our natural resources, and protect and enhance our quality of life. This brochure provides examples of the challenges we face and how USGS science helps decisionmakers to address these challenges.

  9. Basic Energy Sciences: Summary of Accomplishments

    DOE R&D Accomplishments Database

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy-related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user'' facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  10. Basic energy sciences: Summary of accomplishments

    NASA Astrophysics Data System (ADS)

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  11. FWP executive summaries: Basic energy sciences materials sciences programs

    SciTech Connect

    Samara, G.A.

    1996-02-01

    This report provides an Executive Summary of the various elements of the Materials Sciences Program which is funded by the Division of Materials Sciences, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico.

  12. PROJECT SUCCESS: Marine Science. (Introductory Packet, Basic Marine Science Laboratory Techniques, Oceanographic Instruments, Individual Projects, Bibliography).

    ERIC Educational Resources Information Center

    Demaray, Bryan

    Five packets comprise the marine science component of an enrichment program for gifted elementary students. Considered in the introductory section are identification (pre/post measure) procedures. Remaining packets address the following topics (subtopics in parentheses): basic marine science laboratory techniques (microscope techniques and metric…

  13. In defense of basic science funding: today's scientific discovery is tomorrow's medical advance.

    PubMed

    Tessier-Lavigne, Marc

    2013-06-01

    In this address, I will discuss the importance of basic science in tackling our health problems. I will also describe how the funding cuts are damaging our economic competitiveness and turning our young people away from science.

  14. Preparation of Basic and Clinical Sciences Faculty.

    ERIC Educational Resources Information Center

    Adams, Anthony J.

    1995-01-01

    A discussion of basic and clinical science teaching in optometry in the next decade looks at the changing role of primary care and specialist optometrists, the training needs of current and future faculty, recommended curriculum changes, and decision making about delivery of this training. The roles of graduate training, residencies, and…

  15. Basic Physical Science. Apprentice Related Training Module.

    ERIC Educational Resources Information Center

    Rice, Eric

    One in a series of core instructional materials for apprentices to use during the first or second years of apprentice-related subjects training, this booklet deals with basic physical science. The first section consists of an outline of the content and scope of the core materials as well as a self-assessment pretest. Covered in the four…

  16. Integration of Basic Sciences in Health's Courses

    ERIC Educational Resources Information Center

    Azzalis, L. A.; Giavarotti, L.; Sato, S. N.; Barros, N. M. T.; Junqueira, V. B. C.; Fonseca, F. L. A.

    2012-01-01

    Concepts from disciplines such as Biochemistry, Genetics, Cellular and Molecular Biology are essential to the understanding and treatment of an elevated number of illnesses, but often they are studied separately, with no integration between them. This article proposes a model for basic sciences integration based on problem-based learning (PBL) and…

  17. Speaking of food: connecting basic and applied plant science.

    PubMed

    Gross, Briana L; Kellogg, Elizabeth A; Miller, Allison J

    2014-10-01

    The Food and Agriculture Organization (FAO) predicts that food production must rise 70% over the next 40 years to meet the demands of a growing population that is expected to reach nine billion by the year 2050. Many facets of basic plant science promoted by the Botanical Society of America are important for agriculture; however, more explicit connections are needed to bridge the gap between basic and applied plant research. This special issue, Speaking of Food: Connecting Basic and Applied Plant Science, was conceived to showcase productive overlaps of basic and applied research to address the challenges posed by feeding billions of people and to stimulate more research, fresh connections, and new paradigms. Contributions to this special issue thus illustrate some interactive areas of study in plant science-historical and modern plant-human interaction, crop and weed origins and evolution, and the effects of natural and artificial selection on crops and their wild relatives. These papers provide examples of how research integrating the basic and applied aspects of plant science benefits the pursuit of knowledge and the translation of that knowledge into actions toward sustainable production of crops and conservation of diversity in a changing climate.

  18. Advanced Cyberinfrastructure Investments Addressing Earth Science Challenges

    NASA Astrophysics Data System (ADS)

    Walton, A. L.; Spengler, S. J.; Zanzerkia, E. E.

    2014-12-01

    The National Science Foundation supports infrastructure development and research into Big Data challenges as part of its long-term cyberinfrastructure strategy. This strategy highlights the critical need to leverage and partner with other agencies, resources and service providers to the U.S. research community. The current cyberinfrastructure and research activities within NSF support advanced technology development, pilot demonstrations of new capabilities for the scientific community in general, and integration and interoperability of data resources across the Geoscience community. These activities include the Data Infrastructure Building Blocks, Big Data and EarthCube programs, among others. Investments are competitively solicited; the resulting portfolio of high performance computing, advanced information systems, new software capabilities, analytics and modeling supports a range of science disciplines. This presentation provides an overview of these research programs, highlighting some of the key investments in advanced analytics, coupled modeling, and seamless collaboration. Examples related to the geosciences, computer-aided discovery and hypothesis generation are highlighted.

  19. Limitations on diversity in basic science departments.

    PubMed

    Leboy, Phoebe S; Madden, Janice F

    2012-08-01

    It has been over 30 years since the beginning of efforts to improve diversity in academia. We can identify four major stages: (1) early and continuing efforts to diversify the pipeline by increasing numbers of women and minorities getting advanced degrees, particularly in science, technology, engineering, and math (STEM); (2) requiring academic institutions to develop their own "affirmative action plans" for hiring and promotion; (3) introducing mentoring programs and coping strategies to help women and minorities deal with faculty practices from an earlier era; (4) asking academic institutions to rethink their practices and policies with an eye toward enabling more faculty diversity, a process known as institutional transformation. The thesis of this article is that research-intensive basic science departments of highly ranked U.S. medical schools are stuck at stage 3, resulting in a less diverse tenured and tenure-track faculty than seen in well-funded science departments of major universities. A review of Web-based records of research-intensive departments in universities with both medical school and nonmedical school departments indicates that the proportion of women and Black faculty in science departments of medical schools is lower than the proportion in similarly research-intensive university science departments. Expectations for faculty productivity in research-intensive medical school departments versus university-based departments may lead to these differences in faculty diversity.

  20. Basic Science for a Secure Energy Future

    NASA Astrophysics Data System (ADS)

    Horton, Linda

    2010-03-01

    Anticipating a doubling in the world's energy use by the year 2050 coupled with an increasing focus on clean energy technologies, there is a national imperative for new energy technologies and improved energy efficiency. The Department of Energy's Office of Basic Energy Sciences (BES) supports fundamental research that provides the foundations for new energy technologies and supports DOE missions in energy, environment, and national security. The research crosses the full spectrum of materials and chemical sciences, as well as aspects of biosciences and geosciences, with a focus on understanding, predicting, and ultimately controlling matter and energy at electronic, atomic, and molecular levels. In addition, BES is the home for national user facilities for x-ray, neutron, nanoscale sciences, and electron beam characterization that serve over 10,000 users annually. To provide a strategic focus for these programs, BES has held a series of ``Basic Research Needs'' workshops on a number of energy topics over the past 6 years. These workshops have defined a number of research priorities in areas related to renewable, fossil, and nuclear energy -- as well as cross-cutting scientific grand challenges. These directions have helped to define the research for the recently established Energy Frontier Research Centers (EFRCs) and are foundational for the newly announced Energy Innovation Hubs. This overview will review the current BES research portfolio, including the EFRCs and user facilities, will highlight past research that has had an impact on energy technologies, and will discuss future directions as defined through the BES workshops and research opportunities.

  1. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    Pursuant to recommendations of the United Nations Conference on the Exploration and Peaceful Uses of Outer Space UNISPACE III and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space UNCOPUOS annual UN European Space Agency workshops on basic space science have been held around the world since 1991 These workshops contribute to the development of astrophysics and space science particularly in developing nations Following a process of prioritization the workshops identified the following elements as particularly important for international cooperation in the field i operation of astronomical telescope facilities implementing TRIPOD ii virtual observatories iii astrophysical data systems iv concurrent design capabilities for the development of international space missions and v theoretical astrophysics such as applications of nonextensive statistical mechanics Beginning in 2005 the workshops focus on preparations for the International Heliophysical Year 2007 IHY2007 The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost ground-based world-wide instrument arrays as lead by the IHY secretariat Further information Wamsteker W Albrecht R and Haubold H J Developing Basic Space Science World-Wide A Decade of UN ESA Workshops Kluwer Academic Publishers Dordrecht 2004 http ihy2007 org http www oosa unvienna org SAP bss ihy2007 index html http www cbpf br GrupPesq StatisticalPhys biblio htm

  2. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    2006-08-01

    Pursuant to recommendations of the United Nations Conference on the Exploration and Peaceful Uses of Outer Space (UNISPACE III) and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS), annual UN/ European Space Agency workshops on basic space science have been held around the world since 1991. These workshops contribute to the development of astrophysics and space science, particularly in developing nations. Following a process of prioritization, the workshops identified the following elements as particularly important for international cooperation in the field: (i) operation of astronomical telescope facilities implementing TRIPOD, (ii) virtual observatories, (iii) astrophysical data systems, (iv) concurrent design capabilities for the development of international space missions, and (v) theoretical astrophysics such as applications of nonextensive statistical mechanics. Beginning in 2005, the workshops focus on preparations for the International Heliophysical Year 2007 (IHY2007). The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost, ground-based, world-wide instrument arrays as lead by the IHY secretariat. Wamsteker, W., Albrecht, R. and Haubold, H.J.: Developing Basic Space Science World-Wide: A Decade of UN/ESA Workshops. Kluwer Academic Publishers, Dordrecht 2004. http://ihy2007.org http://www.unoosa.org/oosa/en/SAP/bss/ihy2007/index.html http://www.cbpf.br/GrupPesq/StatisticalPhys/biblio.htm

  3. Assessing what to address in science communication

    PubMed Central

    Bruine de Bruin, Wändi; Bostrom, Ann

    2013-01-01

    As members of a democratic society, individuals face complex decisions about whether to support climate change mitigation, vaccinations, genetically modified food, nanotechnology, geoengineering, and so on. To inform people’s decisions and public debate, scientific experts at government agencies, nongovernmental organizations, and other organizations aim to provide understandable and scientifically accurate communication materials. Such communications aim to improve people’s understanding of the decision-relevant issues, and if needed, promote behavior change. Unfortunately, existing communications sometimes fail when scientific experts lack information about what people need to know to make more informed decisions or what wording people use to describe relevant concepts. We provide an introduction for scientific experts about how to use mental models research with intended audience members to inform their communication efforts. Specifically, we describe how to conduct interviews to characterize people’s decision-relevant beliefs or mental models of the topic under consideration, identify gaps and misconceptions in their knowledge, and reveal their preferred wording. We also describe methods for designing follow-up surveys with larger samples to examine the prevalence of beliefs as well as the relationships of beliefs with behaviors. Finally, we discuss how findings from these interviews and surveys can be used to design communications that effectively address gaps and misconceptions in people’s mental models in wording that they understand. We present applications to different scientific domains, showing that this approach leads to communications that improve recipients’ understanding and ability to make informed decisions. PMID:23942122

  4. Assessing what to address in science communication.

    PubMed

    Bruine de Bruin, Wändi; Bostrom, Ann

    2013-08-20

    As members of a democratic society, individuals face complex decisions about whether to support climate change mitigation, vaccinations, genetically modified food, nanotechnology, geoengineering, and so on. To inform people's decisions and public debate, scientific experts at government agencies, nongovernmental organizations, and other organizations aim to provide understandable and scientifically accurate communication materials. Such communications aim to improve people's understanding of the decision-relevant issues, and if needed, promote behavior change. Unfortunately, existing communications sometimes fail when scientific experts lack information about what people need to know to make more informed decisions or what wording people use to describe relevant concepts. We provide an introduction for scientific experts about how to use mental models research with intended audience members to inform their communication efforts. Specifically, we describe how to conduct interviews to characterize people's decision-relevant beliefs or mental models of the topic under consideration, identify gaps and misconceptions in their knowledge, and reveal their preferred wording. We also describe methods for designing follow-up surveys with larger samples to examine the prevalence of beliefs as well as the relationships of beliefs with behaviors. Finally, we discuss how findings from these interviews and surveys can be used to design communications that effectively address gaps and misconceptions in people's mental models in wording that they understand. We present applications to different scientific domains, showing that this approach leads to communications that improve recipients' understanding and ability to make informed decisions.

  5. Annual report, Basic Sciences Branch, FY 1991

    SciTech Connect

    Not Available

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  6. Annual report, Basic Sciences Branch, FY 1991

    SciTech Connect

    Not Available

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  7. Basic Science Living Skills for Today's World. Teacher's Edition.

    ERIC Educational Resources Information Center

    Zellers (Robert W.) Educational Services, Johnstown, PA.

    This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…

  8. 75 FR 41838 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee...; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown Building, 1000 Independence...

  9. 78 FR 6088 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Basic Energy Sciences, U.S. Department of Energy; SC-22/Germantown Building, 1000 Independence Avenue...

  10. 77 FR 5246 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. ] SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory... Perine; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown Building,...

  11. Student Perceptions of Using Games to Address Science Literacy

    ERIC Educational Resources Information Center

    Keller, Cara M.

    2012-01-01

    The purpose of this qualitative evaluative case study was to gain insight into how students perceived the efficacy of using games to address their science literacy concerns. Scientists in the United States are concerned with the lack of science literacy. The No Child Left Behind Act of 2001 requires proficiency in reading, mathematics, language…

  12. Basic Sciences Branch annual report, FY 1990

    SciTech Connect

    Not Available

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  13. Basic Sciences Branch annual report, FY 1990

    SciTech Connect

    Not Available

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  14. Clinical competencies and the basic sciences: an online case tutorial paradigm for delivery of integrated clinical and basic science content.

    PubMed

    DiLullo, Camille; Morris, Harry J; Kriebel, Richard M

    2009-10-01

    Understanding the relevance of basic science knowledge in the determination of patient assessment, diagnosis, and treatment is critical to good medical practice. One method often used to direct students in the fundamental process of integrating basic science and clinical information is problem-based learning (PBL). The faculty facilitated small group discussion format traditionally used for PBL is a significant challenge for faculty and facilities with a large class. To provide inductive learning to a large class early in the preclerkship curriculum, a series of online, case-based tutorials was created using the method of inquiry-based learning. The tutorial paradigm is designed to challenge students through a guided inquiry process in which clinical skills and basic science information are seamlessly joined. The psychosocial dimension of patient care is added to the documented case presentation of the tutorials in the form of patient/physician history taking and physical examination videos. These videos augment the written case with additional information providing the student with visual exposure in methods of patient communication and appropriate professional patient/physician interactions that address competencies of patient care, communication, and professionalism. The tutorials were made available via learning management system course sites. The study tracked usage of the tutorials by 270 first-year medical students.

  15. 78 FR 47677 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of... Sciences Advisory Committee's (BESAC) charter will be renewed for a two-year period. The Committee will provide advice and recommendations to the Office of Science on the Basic Energy Sciences...

  16. 76 FR 48147 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of renewal of the Basic Energy Sciences Advisory Committee. SUMMARY: Pursuant to Section 14(a)(2)(A) of...

  17. 76 FR 41234 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  18. 77 FR 41395 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  19. 78 FR 38696 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  20. Developing Basic Space Science World-Wide

    NASA Astrophysics Data System (ADS)

    Wamsteker, W.; Albrecht, Rudolf; Haubold, Hans J.

    2004-03-01

    When the first United Nations/European Space Agency Workshop for Basic Space Science was planned to be held in Bangalore, India (1991) on the invitation of ISRO, few of those involved could expect that a unique forum was going to be created for scientific dialogue between scientists from developing and industrialized nations. As the format of the first workshop was on purpose left free with time for presentations, working sessions, and plenary discussions, the workshop was left to find its own dynamics. After a decade of UN/ESA Workshops, this book brings together the historical activities, the plans which have been developed over the past decade in the different nations, and the results which have materialized during this time in different developing nations. It aims to achieve for development agencies to be assisted in ways to find more effective tools for the application of development aid. The last section of the book contains a guide for teachers to introduce astrophysics into university physics courses. This will be of use to teachers in many nations. Everything described in this book is the result of a truly collective effort from all involved in all UN/ESA workshops. The mutual support from the participants has helped significantly to implement some of the accomplishments described in the book. Rather than organizing this book in a subject driven way, it is essentially organized according to the common economic regions of the world, as defined by the United Nations (Africa, Asia and the Pacific, Europe, Latin America and the Caribbean, Western Asia). This allows better recognition of the importance of a regional (and at times) global approach to basic space science for the developing nation's world wide. It highlights very specific scientific investigations which have been completed successfully in the various developing nations. The book supplements the published ten volumes of workshop proceedings containing scientific papers presented in the workshops

  1. Student Perceptions of Using Games to Address Science Literacy

    NASA Astrophysics Data System (ADS)

    Keller, Cara M.

    The purpose of this qualitative evaluative case study was to gain insight into how students perceived the efficacy of using games to address their science literacy concerns. Scientists in the United States are concerned with the lack of science literacy. The No Child Left Behind Act of 2001 requires proficiency in reading, mathematics, language arts, and science by the completion of the 2013--2014 school year. The high school participating in this study received substandard test scores on both the 2009 state graduation test and the science portion of the ACT test. The research question included understanding how students perceive the use of games in addressing their science literacy needs. The data from the student journals, field notes, and transcribed class discussions were analyzed using a 6 step method that included coding the data into main themes. The triangulated data were used to both gain insight into student perspective and inform game development. Constructivist theories formed the conceptual framework of the study. The findings of the study suggested that games may prove a valuable tool in science literacy attainment. The study indicated that games were perceived by the students to be effective tools in meeting their learning needs. Implications for positive social change included providing students, educators, and administrators with game resources that can be used to meet the science learning needs of struggling students, thereby improving science scores on high stakes tests.

  2. Strategic Science to Address Current and Future Space Weather Needs

    NASA Astrophysics Data System (ADS)

    Mannucci, A. J.; Schwadron, N.; Antiochos, S. K.; Bhattacharjee, A.; Bisi, M. M.; Gopalswamy, N.; Kamalabadi, F.; Pulkkinen, A. A.; Tobiska, W. K.; Weimer, D. R.; Withers, P.

    2014-12-01

    NASA's Living With a Star (LWS) program has contributed a wealth of scientific knowledge that is relevant to space weather and user needs. A targeted approach to science questions has resulted in leveraging new scientific knowledge to improve not only our understanding of the Heliophysics domain, but also to develop predictive capabilities in key areas of LWS science. This fascinating interplay between science and applications promises to benefit both domains. Scientists providing feedback to the LWS program are now discussing an evolution of the targeted approach that explicitly considers how new science improves, or enables, predictive capability directly. Long-term program goals are termed "Strategic Science Areas" (SSAs) that address predictive capabilities in six specific areas: geomagnetically induced currents, satellite drag, solar energetic particles, ionospheric total electron content, radio frequency scintillation induced by the ionosphere, and the radiation environment. SSAs are organized around user needs and the impacts of space weather on society. Scientists involved in the LWS program identify targeted areas of research that reference (or bear upon) societal needs. Such targeted science leads to new discoveries and is one of the valid forms of exploration. In this talk we describe the benefits of targeted science, and how addressing societal impacts in an appropriate way maintains the strong science focus of LWS, while also leading to its broader impacts.

  3. Exploring the basic science of prolapse meshes

    PubMed Central

    Liang, Rui; Knight, Katrina; Abramowitch, Steve; Moalli, Pamela A.

    2016-01-01

    Purpose of review Polypropylene mesh has been widely used in the surgical repair of pelvic organ prolapse. However, low but persistent rates of complications related to mesh, most commonly mesh exposure and pain, have hampered its use. Complications are higher following transvaginal implantation prompting the Food and Drug Administration to release two public health notifications warning of complications associated with transvaginal mesh use (PHN 2008 and 2011) and to upclassify transvaginal prolapse meshes from Class II to Class III devices. Although there have been numerous studies to determine the incidence and management of mesh complications as well as impact on quality of life, few studies have focused on mechanisms. Recent findings In this review, we summarize the current understanding of how mesh textile properties and mechanical behavior impact vaginal structure and function, as well as the local immune response. We also discuss how mesh properties change in response to loading. Summary We highlight a few areas of current and future research to emphasize collaborative strategies that incorporate basic science research to improve patient outcomes. PMID:27517341

  4. 76 FR 8358 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Energy Sciences; U.S. Department of Energy; Germantown Building, 1000 Independence Avenue,...

  5. 75 FR 6369 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Energy Sciences; U.S. Department of Energy; Germantown Building, Independence Avenue, Washington,...

  6. Basic Science Research and the Protection of Human Research Participants

    NASA Astrophysics Data System (ADS)

    Eiseman, Elisa

    2001-03-01

    Technological advances in basic biological research have been instrumental in recent biomedical discoveries, such as in the understanding and treatment of cancer, HIV/AIDS, and heart disease. However, many of these advances also raise several new ethical challenges. For example, genetic research may pose no physical risk beyond that of obtaining the initial blood sample, yet it can pose significant psychological and economic risks to research participants, such as stigmatization, discrimination in insurance and employment, invasion of privacy, or breach of confidentiality. These harms may occur even when investigators do not directly interact with the person whose DNA they are studying. Moreover, this type of basic research also raises broader questions, such as what is the definition of a human subject, and what kinds of expertise do Institutional Review Boards (IRBs) need to review the increasingly diverse types of research made possible by these advances in technology. The National Bioethics Advisory Commission (NBAC), a presidentially appointed federal advisory committee, has addressed these and other ethical, scientific and policy issues that arise in basic science research involving human participants. Two of its six reports, in particular, have proposed recommendations in this regard. "Research Involving Human Biological Materials: Ethical and Policy Guidance" addresses the basic research use of human tissues, cells and DNA and the protection of human participants in this type of research. In "Ethical and Policy Issues in the Oversight of Human Research" NBAC proposes a definition of research involving human participants that would apply to all scientific disciplines, including physical, biological, and social sciences, as well as the humanities and related professions, such as business and law. Both of these reports make it clear that the protection of research participants is key to conducting ethically sound research. By ensuring that all participants in

  7. Addressing the “Major Unrest” in science

    NASA Astrophysics Data System (ADS)

    Simarski, Lynn Teo

    “The politics of science and technology has returned with a vengeance—or perhaps it never left,” Mary Good, head of the National Science Board, told a gathering of Washington scientists and policy-makers on March 30. Good addressed a spectrum of U.S. science issues, providing a chance to take the pulse of an important science policy- maker. The 24-member board that she chairs sets policy for the National Science Foundation.Good strongly criticized current attempts in Congress and elsewhere to create one over-arching policy for science, technology, and competitiveness. “We need to get these three areas separated out,” Good said. “They are truly three different subjects.” The issue is part of an on-going debate in Congress over the character of U.S. industrial policy. Congressional committees often ask how a science program under scrutiny will contribute to the nation's ability to compete in the world marketplace. “My cohorts in industry say that the one thing we must have from the universities is quality manpower; that's the first priority,” Good said. Second on the list is to forge links between academia and industry to keep industry's “in-house talent” at the cutting edge.

  8. Basic research supported by the Office of Basic Energy Sciences, U.S. Department of Energy

    SciTech Connect

    Kelley, R.D.

    1995-08-01

    This presentation will outline the basic research activities of the Office of Basic Energy Sciences (BES) of the U.S. Department of Energy. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department`s mission. Of particular focus in the presentation are the research programs, amounting to about $10 million, supported by the Materials Sciences Division and the Chemical Sciences Division which are fairly directly related to electrochemical technologies.

  9. NEW APPROACHES: Addressing students' common difficulties in basic electricity by qualitative simulation-based activities

    NASA Astrophysics Data System (ADS)

    Ronen, M.; Eliahu, M.

    1997-11-01

    Simulation-based activities provide students with an opportunity to compare their physical intuition with the behaviour of the model and can sometimes offer unique advantages over other methods. This article presents various approaches to the development of qualitative simulation- based activities and describes how these activities can be addressed to students' common difficulties in basic electricity.

  10. Researchers warn of neglect to basic science

    NASA Astrophysics Data System (ADS)

    Banks, Michael

    2010-03-01

    Russia is losing its standing as a scientific powerhouse and its science is in a state of decline, according to a new report by the information-services provider Thomson Reuters. Entitled "The New Geography of Science: Research and Collaboration in Russia", the report warns that the country's research base "has a problem, and it shows little sign of a solution".

  11. Populations. Basic Edition. Science for Micronesia.

    ERIC Educational Resources Information Center

    Trust Territory of the Pacific Islands Dept. of Education, Saipan.

    This teacher's guide is for an elementary school science unit designed for use with third grade (or older) children in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of…

  12. TEACHING PHYSICS: Visual Basic science simulations

    NASA Astrophysics Data System (ADS)

    Evans, J. G.

    2000-01-01

    We are exploring the use of science simulation/modelling programs for teaching a variety of science concepts across the age range. The programs have been converted from the original RMBasic thanks to technological advances in equipment. We find that the programs complement practical work and allow in-depth analysis using multi-tasking with other programs.

  13. Integrating basic science without integrating basic scientists: reconsidering the place of individual teachers in curriculum reform.

    PubMed

    Hopkins, Robin; Pratt, Daniel; Bowen, Judith L; Regehr, Glenn

    2015-02-01

    The call for integration of the basic and clinical sciences plays prominently in recent conversations about curricular change in medical education; however, history shows that, like other concepts related to curricular reform, integration has been continually revisited, leading to incremental change but no meaningful transformation. To redress this cycle of "change without difference," the medical education community must reexamine the approach that dominates medical education reform efforts and explore alternative perspectives that may help to resolve the cyclical "problem" of recommending but not effecting integration. To provide a different perspective on implementing integration, the authors of this Perspective look to the domain of educational change as an approach to examining the transitions that occur within complex and evolving environments. This area of literature both acknowledges the multiple levels involved in change and emphasizes the need not only to address systemic structure but also to prioritize individuals during times of transition. The struggle to implement curricular integration in medical education may stem from the fact that reform efforts appear to focus largely on transformation at the level of curricular structure as opposed to considering what learning needs to occur at each level of change and highlighting the individual as the educational change literature suggests. To bring appropriate attention to the place of individual educators, especially basic scientists, the medical education community should explore how the mandate to integrate clinically relevant material may impact these faculty and the teaching of their domains.

  14. BASIC STEPS IN DESIGNING SCIENCE LABORATORIES.

    ERIC Educational Resources Information Center

    WHITNEY, FRANK L.

    PLANNERS OF CURRENT UNIVERSITY LABORATORIES OFTEN MAKE THE SAME MISTAKES MADE BY INDUSTRIAL LABORATORIES 20 YEARS AGO. THIS CAN BE REMEDIED BY INCREASED COMMUNICATION BETWEEN SCIENTISTS AND DESIGNERS IN SEMINARS DEFINING THE BASIC NEEDS OF A PARTICULAR LABORATORY SITUATION. ELECTRONIC AND MECHANICAL EQUIPMENT ACCOUNT FOR OVER 50 PER CENT OF TOTAL…

  15. [Basic areas of medical science in Uzbekistan].

    PubMed

    Abdullakhodzhaeva, M S

    2016-01-01

    The paper considers the issues of medicine development in the Republic of Uzbekistan and the contribution made by prominent scientists developing effective methods for diagnosing and treating different diseases in medical science. A great part is assigned to medical science advances in our country. To solve the urgent problems of public health, much attention is given to the training of scientific manpower, the setting up of specialized research and practical medical centers of different profile, research laboratories of medical higher educational establishments as a base for conducting researches and investigations, which will be able to improve the quality of medical care to the population and corresponds to a health care reform program.

  16. Office of Basic Energy Sciences 1990 summary report

    SciTech Connect

    Not Available

    1990-10-01

    Basic research is an important investment in the future which will help the US maintain and enhance its economic strength. The Office of Basic Energy Sciences (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals -- energy self-sufficiency, improved health and quality of life for all, economic growth, national security -- depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions.

  17. Office of Basic Energy Sciences 1990 summary report

    NASA Astrophysics Data System (ADS)

    1990-10-01

    Basic research is an important investment in the future which will help the U.S. maintain and enhance its economic strength. The Office of Basic Energy Sciences' (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals -- energy self-sufficiency, improved health and quality of life for all, economic growth, national security -- depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions.

  18. Keynote Address: Science Since the Medicean Stars and the Beagle

    NASA Astrophysics Data System (ADS)

    Partridge, B.; Hillenbrand, L. A.; Grinspoon, D.

    2010-08-01

    In 2009, the world celebrates both the International Year of Astronomy (IYA), commemorating the 400th anniversary of Galileo's first observations of the heavens with his telescope, and the 200th anniversary of the birth of Charles Darwin and the 150th anniversary of the publication of his Origin of Species, a key impetus for the 2009 Year of Science. In this keynote address, the three presenters (distinguished scientists themselves) will reflect on how these recent centuries of astronomical and scientific discovery have changed our perspectives about the universe, the natural world, and ourselves—and underpin our education and public outreach efforts to help ensure continued scientific advance in the future.

  19. Teaching Basic Probability in Undergraduate Statistics or Management Science Courses

    ERIC Educational Resources Information Center

    Naidu, Jaideep T.; Sanford, John F.

    2017-01-01

    Standard textbooks in core Statistics and Management Science classes present various examples to introduce basic probability concepts to undergraduate business students. These include tossing of a coin, throwing a die, and examples of that nature. While these are good examples to introduce basic probability, we use improvised versions of Russian…

  20. Parsesciencing: A Basic Science Mode of Inquiry.

    PubMed

    Parse, Rosemarie Rizzo

    2016-10-01

    The purpose of this article is to introduce the language for the mode of inquiry, now known as Parsesciencing. The language for the Humanbecoming Hermeneutic Sciencing was introduced in an earlier volume of Nursing Science Quarterly. Language both reflects and cocreates meaning. The language of sciencing is everchanging; it is an evolutionary emergent, shifting as new ideas cocreate horizons beyond. The language set forth here is to articulate more explicitly meanings of the modes of inquiry consistent with the humanbecoming paradigm and distinct from modes of inquiry in other disciplines. In dwelling with the findings of published and unpublished studies that were guided by humanbecoming, new insights arose, and with creative conceptualizing these new insights gave birth to new meanings, thus different language. The language introduced here includes the following: Parsesciencing as coming to know the meanings of universal humanuniverse living experiences, horizon of inquiry, foreknowings, inquiry stance, mode of inquiry, historians, dialoging-engaging, scholar, distilling-fusing, discerning extant moment, transmogrifying, transsubstantiating, and newknowings. Note: an example of the new language with a Parsesciencing inquiry on the universal humanuniverse living experience of feeling unsure by Sandra Bunkers appears later in this issue.

  1. The Museum of Science and Industry Basic List of Children's Science Books, 1986.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    This first supplement to the Museum of Science and Industry Basic List of Children's Science Books contains books received for the museum's 13th annual children's science book fair. Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; environment/conservation;…

  2. Science and the Nonscience Major: Addressing the Fear Factor in the Chemical Arena Using Forensic Science

    ERIC Educational Resources Information Center

    Labianca, Dominick A.

    2007-01-01

    This article describes an approach to minimizing the "fear factor" in a chemistry course for the nonscience major, and also addresses relevant applications to other science courses, including biology, geology, and physics. The approach emphasizes forensic science and affords students the opportunity to hone their analytical skills in an…

  3. The Basic Mathematics of Astronomy: A Sourcebook for Science Teachers.

    ERIC Educational Resources Information Center

    Therkelsen, Edward Robert

    An attempt was made in this study to determine if there was a need for a sourcebook of the basic mathematics of astronomy for secondary school science teachers. Science teachers involved and interested in the teaching of astronomy were located through letters to the superintendents of the 400 largest school districts in the United States. Names…

  4. Family Science Activities for Adult Basic and Literacy Education.

    ERIC Educational Resources Information Center

    Community Action Southwest, Waynesburg, PA.

    A staff development project created a series of family science activities to be used in adult basic and literacy education (ABLE) and family literacy programs and a training guide for staff and volunteers. The training guide provides background principles and concepts for science activities. The activities identify materials and indicate ways the…

  5. Review of basic science advances in HIV.

    PubMed

    Stevenson, Mario

    2012-01-01

    The Conference on Retroviruses and Opportunistic Infections (CROI) is held annually to provide a forum for scientists to hear the most recent advances in the field of HIV and AIDS research. Although the conference has a primary mission to showcase advances in the prevention and management of HIV-1 infection and opportunistic infections (in particular, tuberculosis and hepatitis C virus [HCV]), there continues to be a strong basic research component. Research on cellular factors that influence the interplay between the virus and the host cell, and especially, cellular factors that antagonize viral replication, had the greatest presence at the conference. In the area of retroviral pathogenesis, research on viral reservoirs and mechanisms of viral persistence in the face of antiretroviral therapy generated considerable interest. Research on mechanisms of viral persistence is beginning to reveal strategies, some of which were the focus of presentations at CROI, to eliminate long-lived viral reservoirs.

  6. Welding As Science: Applying Basic Engineering Principles to the Discipline

    NASA Technical Reports Server (NTRS)

    Nunes, A. C., Jr.

    2010-01-01

    This Technical Memorandum provides sample problems illustrating ways in which basic engineering science has been applied to the discipline of welding. Perhaps inferences may be drawn regarding optimal approaches to particular welding problems, as well as for the optimal education for welding engineers. Perhaps also some readers may be attracted to the science(s) of welding and may make worthwhile contributions to the discipline.

  7. Brown Superfund Basic research Program: a multistakeholder partnership addresses real-world problems in contaminated communities.

    PubMed

    Senier, Laura; Hudson, Benjamin; Fort, Sarah; Hoover, Elizabeth; Tillson, Rebecca; Brown, Phil

    2008-07-01

    The NIEHS funds several basic and applied research programs, many of which also require research translation or outreach. This paper reports on a project by the Brown University Superfund Basic Research Program (SBRP), in which outreach and research translation teams collaborated with state regulatory agency personnel and community activists on a legislative initiative to mitigate the financial impacts of living in a contaminated community. The Environmentally Compromised Home Ownership (ECHO) program makes home equity loans of up to $25,000 available to qualified applicants. This collaboration provides a case study in community engagement and demonstrates how research translation and outreach activities that are clearly differentiated yet well-integrated can improve a suite of basic and applied research. Although engaging diverse constituencies can be difficult community-engaged translation and outreach have the potential to make research findings more useful to communities, address some of the social impacts of contamination, and empower stakeholders to pursue their individual and collectively held goals for remediation. The NIEHS has recently renewed its commitment to community-engaged research and advocacy, making this an optimal time to reflect on how basic research programs that engage stakeholders through research translation and outreach can add value to the overall research enterprise.

  8. National Institutes of Health addresses the science of diversity.

    PubMed

    Valantine, Hannah A; Collins, Francis S

    2015-10-06

    The US biomedical research workforce does not currently mirror the nation's population demographically, despite numerous attempts to increase diversity. This imbalance is limiting the promise of our biomedical enterprise for building knowledge and improving the nation's health. Beyond ensuring fairness in scientific workforce representation, recruiting and retaining a diverse set of minds and approaches is vital to harnessing the complete intellectual capital of the nation. The complexity inherent in diversifying the research workforce underscores the need for a rigorous scientific approach, consistent with the ways we address the challenges of science discovery and translation to human health. Herein, we identify four cross-cutting diversity challenges ripe for scientific exploration and opportunity: research evidence for diversity's impact on the quality and outputs of science; evidence-based approaches to recruitment and training; individual and institutional barriers to workforce diversity; and a national strategy for eliminating barriers to career transition, with scientifically based approaches for scaling and dissemination. Evidence-based data for each of these challenges should provide an integrated, stepwise approach to programs that enhance diversity rapidly within the biomedical research workforce.

  9. National Institutes of Health addresses the science of diversity

    PubMed Central

    Valantine, Hannah A.; Collins, Francis S.

    2015-01-01

    The US biomedical research workforce does not currently mirror the nation’s population demographically, despite numerous attempts to increase diversity. This imbalance is limiting the promise of our biomedical enterprise for building knowledge and improving the nation’s health. Beyond ensuring fairness in scientific workforce representation, recruiting and retaining a diverse set of minds and approaches is vital to harnessing the complete intellectual capital of the nation. The complexity inherent in diversifying the research workforce underscores the need for a rigorous scientific approach, consistent with the ways we address the challenges of science discovery and translation to human health. Herein, we identify four cross-cutting diversity challenges ripe for scientific exploration and opportunity: research evidence for diversity’s impact on the quality and outputs of science; evidence-based approaches to recruitment and training; individual and institutional barriers to workforce diversity; and a national strategy for eliminating barriers to career transition, with scientifically based approaches for scaling and dissemination. Evidence-based data for each of these challenges should provide an integrated, stepwise approach to programs that enhance diversity rapidly within the biomedical research workforce. PMID:26392553

  10. The Museum of Science and Industry Basic List of Children's Science Books, 1987.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    Presented is the second annual supplement to the Museum of Science and Industry Basic List of Children's Science Books 1973-1984. In this supplement, children's science books are listed under the headings of animals, astronomy, aviation and space, biography, earth sciences, encyclopedias and reference books, environment and conservation, fiction,…

  11. Addressing Earth Science Data Access Challenges through User Experience Research

    NASA Astrophysics Data System (ADS)

    Hemmings, S. N.; Banks, B.; Kendall, J.; Lee, C. M.; Irwin, D.; Toll, D. L.; Searby, N. D.

    2013-12-01

    The NASA Capacity Building Program (Earth Science Division, Applied Sciences Program) works to enhance end-user capabilities to employ Earth observation and Earth science (EO/ES) data in decision-making. Open data access and user-tailored data delivery strategies are critical elements towards this end. User Experience (UX) and User Interface (UI) research methods can offer important contributions towards addressing data access challenges, particularly at the interface of science application/product development and product transition to end-users. This presentation focuses on developing nation contexts and describes methods, results, and lessons learned from two recent UX/UI efforts conducted in collaboration with NASA: the SERVIRglobal.net redesign project and the U.S. Water Partnership (USWP) Portal development effort. SERVIR, a collaborative venture among NASA, USAID, and global partners, seeks to improve environmental management and climate change response by helping governments and other stakeholders integrate EO and geospatial technologies into decision-making. The USWP, a collaboration among U.S. public and private sectors, harnesses U.S.-based resources and expertise to address water challenges in developing nations. SERVIR's study, conducted from 2010-2012, assessed and tested user needs, preferences, and online experiences to generate a more user-friendly online data portal at SERVIRglobal.net. The portal provides a central access interface to data and products from SERVIR's network of hubs in East Africa, the Hindu Kush Himalayas, and Mesoamerica. The second study, conducted by the USWP Secretariat and funded by the U.S. Department of State, seeks to match U.S.-based water information resources with developing nation stakeholder needs. The USWP study utilizes a multi-pronged approach to identify key design requirements and to understand the existing water data portal landscape. Adopting UX methods allows data distributors to design customized UIs that

  12. XVII International AIDS Conference: From Evidence to Action - Basic science

    PubMed Central

    2009-01-01

    This article focuses on the sessions in which basic science research was presented at the XVII International AIDS Conference (AIDS 2008). It also provides an analysis of basic science issues which generated significant discussion and debate at the conference and are likely to have implications for future laboratory and clinical research. Data presented at AIDS 2008 confirmed the speed with which HIV establishes latent viral reservoirs following infection and the resulting challenges to viral eradication given how effectively HIV proviral RNA inserts itself into human DNA within these reservoirs. Studies also raised questions about the source of residual viremia and how these might be targeted by novel therapeutic approaches. PMID:19811669

  13. Contributions of Basic Sciences to Science of Education. Studies in Educational Administration.

    ERIC Educational Resources Information Center

    Lall, Bernard M.

    The science of education has been influenced by the basic sciences to the extent that educational research now has been able to modernize its approach by accepting and using the basic scientific methodology and experimental techniques. Using primarily the same steps of scientific investigations, education today holds a place of much greater esteem…

  14. Science for What Public? Addressing Equity in American Science Museums and Science Centers

    ERIC Educational Resources Information Center

    Feinstein, Noah Weeth; Meshoulam, David

    2014-01-01

    Science museums and science centers exist (in large part) to bring science to the public. But what public do they serve? The challenge of equity is embodied by the gulf that separates a museum's actual public and the more diverse publics that comprise our society. Yet despite growing scholarly interest in museums and science centers, few…

  15. Curriculum Considerations for Correlating Basic and Clinical Sciences.

    ERIC Educational Resources Information Center

    Mackenzie, Richard S.

    1980-01-01

    Six ways a dentist can profit from the basic sciences are: (1) increased sensitivity to the environment, (2) improved judgment, (3) better explanations to patients, (4) enhanced ability to learn, (5) improved communication with health professionals, and (6) greater role diversity. Literature is reviewed related to mental processes. (Author/MLW)

  16. Pima College Students' Knowledge of Selected Basic Physical Science Concepts.

    ERIC Educational Resources Information Center

    Iadevaia, David G.

    In 1989 a study was conducted at Pima Community College (PCC) to assess students' knowledge of basic physical science concepts. A three-part survey instrument was administered to students in a second semester sociology class, a first semester astronomy class, a second semester Spanish class, and a first semester physics class. The survey…

  17. A brief simulation intervention increasing basic science and clinical knowledge

    PubMed Central

    Sheakley, Maria L.; Gilbert, Gregory E.; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    Background The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. Purpose To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. Methods This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (nl=515) and the intervention group received lecture plus a simulation exercise (nl+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Results Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Discussion Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum. PMID:27060102

  18. BASIC ELECTRICITY. SCIENCE IN ACTION SERIES, NUMBER 14.

    ERIC Educational Resources Information Center

    CASSEL, RICHARD

    THIS TEACHING GUIDE, INVOLVING ACTIVITIES FOR DEVELOPING AN UNDERSTANDING OF BASIC ELECTRICITY, EMPHASIZES STUDENT INVESTIGATIONS RATHER THAN FACTS, AND IS BASED ON THE PREMISE THAT THE MAJOR GOAL IN SCIENCE TEACHING IS THE DEVELOPMENT OF THE INVESTIGATIVE ATTITUDE IN THE STUDENT. ACTIVITIES SUGGESTED INVOLVE SIMPLE DEMONSTRATIONS AND EXPERIMENTS…

  19. Nutrition in pediatrics: basic science and clinical applications

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The first edition of Nutrition in Pediatrics: Basic Science and Clinical Applications was published in 1985 to "...offer a comprehensive review of general concepts of nutrition as they pertain to pediatrics as well as relevant information on the nutritional management of specific disease states." A ...

  20. One Man's Approach to a Basic Course in Geological Sciences.

    ERIC Educational Resources Information Center

    Gould, Stephen Jay

    1984-01-01

    Presents a twofold approach to teaching basic geology based on five principles to make science accessible to students who think they are bored with or afraid of the subject. The approach focuses on: appealing to the mind (to attack boredom) and appealing to the emotions (to attack fear). (BC)

  1. The New Millennium and an Education That Captures the Basic Spirit of Science.

    ERIC Educational Resources Information Center

    Bybee, Rodger W.

    This document discusses reflections of the old and new millennium on education that capture the basic spirit of science. The explanation includes basic scientific ideas in physical sciences, earth systems, solar system and space; living systems; basic scientific thinking; the basic distinction between science and technology; basic connections…

  2. Basic Research in Materials Science and Economic Sustainable Growth

    NASA Astrophysics Data System (ADS)

    Habermeier, H.-U.

    2000-09-01

    The necessity of public funding of basic research has been proclaimed by V. Bush 1945 in the `social contract for science' and this concept has been unanimously accepted as a vital prerequisite for the wealth of nations during the past 50 years. Recent developments gave rise to a paradigm shift away from the Bush's concept. In this paper this development is critically explored and the economical impact of research is discussed. Current evolution in knowledge generation and a change of the political boundary conditions require a new concept for an integrated research system. Examples taken from the semiconductor industry serve as an indicator of the enabling importance of materials science and condensed matter physics in the past. Basic research in materials science of functional ceramics generated new developments that are believed to have similar impact in the future. Already appearing and in the years ahead more emphasized nature of materials science as an multidisciplinary activity serves a model for the proposal of the vision of an integrated system of basic research and education. This is a prerequisite to master the challenges we are facind in the next century. A science based winning culture is the model for the future.

  3. FWP executive summaries: basic energy sciences materials sciences and engineering program (SNL/NM).

    SciTech Connect

    Samara, George A.; Simmons, Jerry A.

    2006-07-01

    This report presents an Executive Summary of the various elements of the Materials Sciences and Engineering Program which is funded by the Division of Materials Sciences and Engineering, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico. A general programmatic overview is also presented.

  4. Integration of basic sciences and clinical sciences in oral radiology education for dental students.

    PubMed

    Baghdady, Mariam T; Carnahan, Heather; Lam, Ernest W N; Woods, Nicole N

    2013-06-01

    Educational research suggests that cognitive processing in diagnostic radiology requires a solid foundation in the basic sciences and knowledge of the radiological changes associated with disease. Although it is generally assumed that dental students must acquire both sets of knowledge, little is known about the most effective way to teach them. Currently, the basic and clinical sciences are taught separately. This study was conducted to compare the diagnostic accuracy of students when taught basic sciences segregated or integrated with clinical features. Predoctoral dental students (n=51) were taught four confusable intrabony abnormalities using basic science descriptions integrated with the radiographic features or taught segregated from the radiographic features. The students were tested with diagnostic images, and memory tests were performed immediately after learning and one week later. On immediate and delayed testing, participants in the integrated basic science group outperformed those from the segregated group. A main effect of learning condition was found to be significant (p<0.05). The results of this study support the critical role of integrating biomedical knowledge in diagnostic radiology and shows that teaching basic sciences integrated with clinical features produces higher diagnostic accuracy in novices than teaching basic sciences segregated from clinical features.

  5. Opportunities for Computational Discovery in Basic Energy Sciences

    NASA Astrophysics Data System (ADS)

    Pederson, Mark

    2011-03-01

    An overview of the broad-ranging support of computational physics and computational science within the Department of Energy Office of Science will be provided. Computation as the third branch of physics is supported by all six offices (Advanced Scientific Computing, Basic Energy, Biological and Environmental, Fusion Energy, High-Energy Physics, and Nuclear Physics). Support focuses on hardware, software and applications. Most opportunities within the fields of~condensed-matter physics, chemical-physics and materials sciences are supported by the Officeof Basic Energy Science (BES) or through partnerships between BES and the Office for Advanced Scientific Computing. Activities include radiation sciences, catalysis, combustion, materials in extreme environments, energy-storage materials, light-harvesting and photovoltaics, solid-state lighting and superconductivity.~ A summary of two recent reports by the computational materials and chemical communities on the role of computation during the next decade will be provided. ~In addition to materials and chemistry challenges specific to energy sciences, issues identified~include a focus on the role of the domain scientist in integrating, expanding and sustaining applications-oriented capabilities on evolving high-performance computing platforms and on the role of computation in accelerating the development of innovative technologies. ~~

  6. Storytelling in Earth sciences: The eight basic plots

    NASA Astrophysics Data System (ADS)

    Phillips, Jonathan

    2012-11-01

    Reporting results and promoting ideas in science in general, and Earth science in particular, is treated here as storytelling. Just as in literature and drama, storytelling in Earth science is characterized by a small number of basic plots. Though the list is not exhaustive, and acknowledging that multiple or hybrid plots and subplots are possible in a single piece, eight standard plots are identified, and examples provided: cause-and-effect, genesis, emergence, destruction, metamorphosis, convergence, divergence, and oscillation. The plots of Earth science stories are not those of literary traditions, nor those of persuasion or moral philosophy, and deserve separate consideration. Earth science plots do not conform those of storytelling more generally, implying that Earth scientists may have fundamentally different motivations than other storytellers, and that the basic plots of Earth Science derive from the characteristics and behaviors of Earth systems. In some cases preference or affinity to different plots results in fundamentally different interpretations and conclusions of the same evidence. In other situations exploration of additional plots could help resolve scientific controversies. Thus explicit acknowledgement of plots can yield direct scientific benefits. Consideration of plots and storytelling devices may also assist in the interpretation of published work, and can help scientists improve their own storytelling.

  7. Making evolutionary biology a basic science for medicine

    PubMed Central

    Nesse, Randolph M.; Bergstrom, Carl T.; Ellison, Peter T.; Flier, Jeffrey S.; Gluckman, Peter; Govindaraju, Diddahally R.; Niethammer, Dietrich; Omenn, Gilbert S.; Perlman, Robert L.; Schwartz, Mark D.; Thomas, Mark G.; Stearns, Stephen C.; Valle, David

    2010-01-01

    New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease. PMID:19918069

  8. Beyond Evolution: Addressing Broad Interactions Between Science and Religion in Science Teacher Education

    NASA Astrophysics Data System (ADS)

    Shane, Joseph W.; Binns, Ian C.; Meadows, Lee; Hermann, Ronald S.; Benus, Matthew J.

    2016-03-01

    Science and religion are two indisputably profound and durable cultural forces with a complex history of interaction. As ASTE members are aware, these interactions often manifest themselves in classrooms and in the surrounding communities. In this essay, we encourage science teacher educators to broaden their perspectives of science-religion interactions so that they may better assist pre- and in-service science teachers with addressing topics such as the age and origins of the universe and biological evolution in an appropriate manner. We first introduce some foundational scholarship into the historical interactions between science and religion as well as current efforts to maintain healthy dialogue between perspectives that are frequently characterized as innately in conflict with or mutually exclusive of one another. Given that biological evolution is the dominant science-religion issue of our day, in particular in the USA, we next summarize the origins and strategies of anti-evolution movements via the rise and persistence of Christian Fundamentalism. We then summarize survey and qualitative sociological research indicating disparities between academic scientists and the general public with regard to religious beliefs to help us further understand our students' worldviews and the challenges they often face in campus-to-classroom transitions. We conclude the essay by providing resources and practical suggestions, including legal considerations, to assist science teacher educators with their curriculum and outreach.

  9. Enlivening basic-science learning with current journal articles.

    PubMed

    Beresford, W A

    1996-01-01

    Pre-clinical medical students are often unconvinced that the basic sciences are clinically valuable. Also, they are hesitant about formulating ideas on their own from non-textbook sources. First-year medical students taking histology or neurobiology were persuaded to consult articles from the current biomedical literature. I set brief short-answer and labeled-sketch questions well before the course theoretical examinations, where the answers counted toward the score. The answers could only be found by reading in articles made available in the laboratory. The articles were chosen to display basic-science knowledge in action in clinical contexts. The questions offer an additional curriculum that can be steered toward, for example, concerns of family practice, mechanisms of common diseases, and topics of fast-increasing clinical importance.

  10. Math Science Partnerships: Addressing the Recommendations of the Glenn Commission

    NASA Astrophysics Data System (ADS)

    Rosen, L. P.

    2002-05-01

    In September, 2000 the National Commission on Mathematics and Science Teaching for the 21st Century released "Before It?s Too Late," a report on the quality of science and mathematics teaching in the nations K-12 classrooms. The report draws three major conclusions: 1) our future well-being depends on how well we educate our children in mathematics and science; 2) we are not doing the job that we should or can do in teaching our children to understand and use ideas from these fields; 3) the most powerful instrument for improving science and mathematics education is to improve teaching in these fields. Based on this analysis, three specific goals were recommended: 1) establish an ongoing system to improve the quality of mathematics and science teaching in grades K-12; 2) increase significantly the number of mathematics and science teachers and improve the quality of their preparation; and 3) improve the working environment and make the teaching profession more attractive for K-12 mathematics and science teachers. This talk will provide an overview of the report and discuss the role of the Math Science Partnership program in meeting its goals.

  11. Addressing Three Common Myths about the Next Generation Science Standards

    ERIC Educational Resources Information Center

    Huff, Kenneth L.

    2016-01-01

    Science education is central to the lives of all Americans. Students face a world where they will frequently be required to make important decisions on issues that range from health care to the environment. Achieving literacy in science will require coherence at all levels and across components of the system including curriculum, assessment, and…

  12. An Integrated Survey System for Addressing Abuse and Misconduct Toward Air Force Trainees During Basic Military Training

    DTIC Science & Technology

    2015-01-01

    An Integrated Survey System for Addressing Abuse and Misconduct Toward Air Force Trainees During Basic Military Training Kirsten M. Keller, Laura...00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE An Integrated Survey System for Addressing Abuse and Misconduct Toward Air Force Trainees During...RAND Project AIR FORCE to help develop an integrated survey system to help address abuse and misconduct toward trainees in the BMT environment. This

  13. Adult Basic Education and Self-Esteem: Practical Strategies for Addressing Self-Esteem Problems among Basic Skills Students.

    ERIC Educational Resources Information Center

    Kirstein, Kurt D.

    The strategies used by practicing adult basic education (ABE) teachers to retain students with poor self-esteem were examined through an Internet survey that was sent to 115 ABE instructors at community colleges in Washington. The survey, which contained questions about the prevalence of poor self-esteem among ABE dropouts, specific behaviors…

  14. "Science Citation Index" Data as a Safety Net for Basic Science Books Considered for Weeding.

    ERIC Educational Resources Information Center

    Burdick, Amrita J.

    1989-01-01

    Describes the use of the "Science Citation Index" in deciding whether to keep older basic science books that have failed to meet other criteria for collection retention. It is concluded that manual searching of the indexes proved feasible and reliable, while the lack of book titles on the online version reduced reliability of weeding…

  15. A hybrid model of mathematics support for science students emphasizing basic skills and discipline relevance

    NASA Astrophysics Data System (ADS)

    Jackson, Deborah C.; Johnson, Elizabeth D.

    2013-09-01

    The problem of students entering university lacking basic mathematical skills is a critical issue in the Australian higher-education sector and relevant globally. The Maths Skills programme at La Trobe University has been developed to address under preparation in the first-year science cohort in the absence of an institutional mathematics support centre. The programme was delivered through first-year science and statistics subjects with large enrolments and focused on basic mathematical skills relevant to each science discipline. The programme offered a new approach to the traditional mathematical support centre or class. It was designed through close collaboration between science subject coordinators and the project leader, a mathematician, and includes resources relevant to science and mathematics questions written in context. Evaluation of the programme showed it improved the confidence of the participating students who found it helpful and relevant. The programme was delivered through three learning modes to allow students to select activities most suitable for them, which was appreciated by students. Mathematics skills appeared to increase following completion of the programme and student participation in the programme correlated positively and highly with academic grades in their relevant science subjects. This programme offers an alternative model for mathematics support tailored to science disciplines.

  16. U.S. Congress addresses risky science business

    NASA Astrophysics Data System (ADS)

    Wakefield, Julie

    A new breed of risk analysis may be coming to the rule-making process, if Republican lawmakers get their way. The Republican Contract with America, among other things, entails a new regulatory contract for America, which may impact on how federal agencies conduct science in the future.The regulatory contract is one chunk of the Republican Contract that the Science Committee has a lot to say about, with primary jurisdiction over Title III of HR9, the Job Creation and Wage Enhancement Act of 1995, which tackles risk assessment head on. Accordingly, hearings were already under way last week before both the Science and Commerce committees in keeping with the timetable of the promised 100-day deadline. The risk assessment section of the bill, Title III, likely will be marked up this week, congressional sources say, if few snags arise during the Administration's testimony, which was slated for last Thursday and Friday.

  17. Basic Science Considerations in Primary Total Hip Replacement Arthroplasty

    PubMed Central

    Mirza, Saqeb B; Dunlop, Douglas G; Panesar, Sukhmeet S; Naqvi, Syed G; Gangoo, Shafat; Salih, Saif

    2010-01-01

    Total Hip Replacement is one of the most common operations performed in the developed world today. An increasingly ageing population means that the numbers of people undergoing this operation is set to rise. There are a numerous number of prosthesis on the market and it is often difficult to choose between them. It is therefore necessary to have a good understanding of the basic scientific principles in Total Hip Replacement and the evidence base underpinning them. This paper reviews the relevant anatomical and biomechanical principles in THA. It goes on to elaborate on the structural properties of materials used in modern implants and looks at the evidence base for different types of fixation including cemented and uncemented components. Modern bearing surfaces are discussed in addition to the scientific basis of various surface engineering modifications in THA prostheses. The basic science considerations in component alignment and abductor tension are also discussed. A brief discussion on modular and custom designs of THR is also included. This article reviews basic science concepts and the rationale underpinning the use of the femoral and acetabular component in total hip replacement. PMID:20582240

  18. Nutritional biology: a neglected basic discipline of nutritional science.

    PubMed

    Döring, Frank; Ströhle, Alexander

    2015-11-01

    On the basis of a scientific-philosophical analysis, this paper tries to show that the approaches in current nutritional science-including its subdisciplines which focus on molecular aspects-are predominantly application-oriented. This becomes particularly evident through a number of conceptual problems characterized by the triad of 'dearth of theoretical foundation,' 'particularist research questions,' and 'reductionist understanding of nutrition.' The thesis presented here is that an interpretive framework based on nutritional biology is able to shed constructive light on the fundamental problems of nutritional science. In this context, the establishment of 'nutritional biology' as a basic discipline in research and education would be a first step toward recognizing the phenomenon of 'nutrition' as an oecic process as a special case of an organism-environment interaction. Modern nutritional science should be substantively grounded on ecological-and therefore systems biology as well as organismic-principles. The aim of nutritional biology, then, should be to develop near-universal 'law statements' in nutritional science-a task which presents a major challenge for the current science system.

  19. Applied social and behavioral science to address complex health problems.

    PubMed

    Livingood, William C; Allegrante, John P; Airhihenbuwa, Collins O; Clark, Noreen M; Windsor, Richard C; Zimmerman, Marc A; Green, Lawrence W

    2011-11-01

    Complex and dynamic societal factors continue to challenge the capacity of the social and behavioral sciences in preventive medicine and public health to overcome the most seemingly intractable health problems. This paper proposes a fundamental shift from a research approach that presumes to identify (from highly controlled trials) universally applicable interventions expected to be implemented "with fidelity" by practitioners, to an applied social and behavioral science approach similar to that of engineering. Such a shift would build on and complement the recent recommendations of the NIH Office of Behavioral and Social Science Research and require reformulation of the research-practice dichotomy. It would also require disciplines now engaged in preventive medicine and public health practice to develop a better understanding of systems thinking and the science of application that is sensitive to the complexity, interactivity, and unique elements of community and practice settings. Also needed is a modification of health-related education to ensure that those entering the disciplines develop instincts and capacities as applied scientists.

  20. Characteristics of physicians engaged in basic science: a questionnaire survey of physicians in basic science departments of a medical school in Japan.

    PubMed

    Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji

    2012-01-01

    The number of physicians engaged in basic science and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study aimed to determine the characteristics of physicians who are engaged in basic science in efforts to recruit talent. A questionnaire was distributed to all 30 physicians in the basic science departments of Juntendo University School of Medicine. Question items inquired about sex, years since graduation, years between graduation and time entering basic science, clinical experience, recommending the career to medical students, expected obstacles to students entering basic science, efforts to inspire students in research, increased number of lectures and practical training sessions on research, and career choice satisfaction. Correlations between the variables were examined using χ(2) tests. Overall, 26 physicians, including 7 female physicians, returned the questionnaire (response rate 86.7%). Most physicians were satisfied with their career choice. Medical students were deemed not to choose basic science as their future career, because they aimed to become clinicians and because they were concerned about salary. Women physicians in basic science departments were younger than men. Women physicians also considered themselves to make more efforts in inspiring medical students to be interested in research. Moreover, physicians who became basic scientists earlier in their career wanted more research-related lectures in medical education. Improving physicians' salaries in basic science is important to securing talent. In addition, basic science may be a good career path for women physicians to follow.

  1. A straightforward guide to the basic science behind arrhythmogenesis.

    PubMed

    Dumotier, Berengere M

    2014-12-01

    The underlying mechanisms behind cardiac arrhythmias are described in this manuscript. In clinical practice, significant arrhythmias are unpredictable, and under some conditions, potentially life-threatening. How can basic science help improve our understanding of molecular entities and factors behind the arrhythmia to advance, develop, adapt or deliver available medications? Structural heart disease and remodelling (eg, heart failure, cardiomyopathy), the presence of modulating factors (ie, diabetes mellitus, autonomic nervous system), genetic predispositions (ie, channelopathies) are considerable preconditions, and influence the development of an arrhythmia. Cardiac arrhythmias may indeed share common basic mechanisms, while elements and substrates perpetuating these may be different and ultimately manifest as various ECG abnormalities. This article lists cellular and subcellular iatrogenic disorders responsible for abnormal impulse generation, or conduction disturbances, including the latest development in theories and biological research, for a better understanding of cellular disorders behind arrhythmogenesis.

  2. Science for Energy Technology: Strengthening the Link Between Basic Research and Industry

    SciTech Connect

    2010-04-01

    The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding.Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a real and immediate impact on cost, reliability, and performance of technology, and ultimately a transformative impact on our economy. With its broad research base and unique scientific user facilities, the DOE Office of Basic Energy Sciences (BES) is ideally positioned to address these needs. BES has laid

  3. The United Nations Basic Space Science Initiative for IHY 2007

    NASA Astrophysics Data System (ADS)

    Gopalswamy, N.; Davila, J. M.; Thompson, B. J.; Haubold, H.

    2006-08-01

    The United Nations, in cooperation with national and international space-related agencies and organizations, has been organizing annual workshops since 1990 on basic space science, particularly for the benefit of scientists and engineers from developing nations. The United Nations Office for Outer Space Affairs, through the IHY Secretariat and the United Nations Basic Space Science Initiative (UNBSSI) will assist scientists and engineers from all over the world in participating in the International Heliophysical Year (IHY) 2007. A major thrust of the IHY/UNBSSI program is to deploy arrays of small, inexpensive instruments such as magnetometers, radio telescopes, GPS receivers, all-sky cameras, etc. around the world to provide global measurements of ionospheric and heliospheric phenomena. The small instrument program is envisioned as a partnership between instrument providers, and instrument hosts in developing countries. The lead scientist will provide the instruments (or fabrication plans for instruments) in the array; the host country will provide manpower, facilities, and operational support to obtain data with the instrument typically at a local university. Funds are not available through the IHY to build the instruments; these must be obtained through the normal proposal channels. However all instrument operational support for local scientists, facilities, data acquisition, etc will be provided by the host nation. It is our hope that the IHY/UNBSSI program can facilitate the deployment of several of these networks world wide. Existing data bases and relevant software tools that can will be identified to promote space science activities in developing countries. Extensive data on space science have been accumulated by a number of space missions. Similarly, long-term data bases are available from ground based observations. These data can be utilized in ways different from originally intended for understanding the heliophysical processes. This paper provides an

  4. Computer animation and improved student comprehension of basic science concepts.

    PubMed

    Thatcher, Jack D

    2006-01-01

    Many medical students have difficulty learning basic science, either because they find the material challenging to comprehend or because they believe it has limited clinical application. Computer-assisted instruction (CAI)--ie, computer animation--can clarify instruction by allowing students to visualize complex, dynamic processes in an interesting presentation. At West Virginia School of Osteopathic Medicine (WVSOM) in Lewisburg, a series of computer animations have been developed to present concepts in molecular and cellular biology. The author conducted an investigation to compare the efficacy of one representative computer animation with that of traditional textbook material. The subjects were 22 students who had been admitted to WVSOM but who had not yet begun classes. The experimental design of the study consisted of a prelesson test, a lesson, and a postlesson test. The lesson explained the process of deoxyribonucleic acid (DNA) replication using either a computer animation (n=12) or a chapter from a textbook (n=10). Lesson comprehension as measured by the tests was significantly higher for subjects who used the computer animation than for subjects who used the textbook (P<.01). Furthermore, reviewing the text after studying with the computer animation did not raise test scores, suggesting that the animation was sufficient for learning and the text was unnecessary. After the study, a majority of subjects indicated a preference for the animation over the text. These results demonstrate that CAI can be an effective tool for relating basic science to medical students by improving comprehension and eliciting interest in the lessons.

  5. Opportunities for discovery: Theory and computation in Basic Energy Sciences

    SciTech Connect

    Harmon, Bruce; Kirby, Kate; McCurdy, C. William

    2005-01-11

    New scientific frontiers, recent advances in theory, and rapid increases in computational capabilities have created compelling opportunities for theory and computation to advance the scientific mission of the Office of Basic Energy Sciences (BES). The prospects for success in the experimental programs of BES will be enhanced by pursuing these opportunities. This report makes the case for an expanded research program in theory and computation in BES. The Subcommittee on Theory and Computation of the Basic Energy Sciences Advisory Committee was charged with identifying current and emerging challenges and opportunities for theoretical research within the scientific mission of BES, paying particular attention to how computing will be employed to enable that research. A primary purpose of the Subcommittee was to identify those investments that are necessary to ensure that theoretical research will have maximum impact in the areas of importance to BES, and to assure that BES researchers will be able to exploit the entire spectrum of computational tools, including leadership class computing facilities. The Subcommittee s Findings and Recommendations are presented in Section VII of this report.

  6. Adult-Rated Oceanography Part 1: A Project Integrating Ocean Sciences into Adult Basic Education Programs.

    NASA Astrophysics Data System (ADS)

    Cowles, S.; Collier, R.; Torres, M. K.

    2004-12-01

    Busy scientists seek opportunities to implement education and outreach efforts, but often don't know where to start. One easy and tested method is to form collaborations with federally-funded adult education and adult literacy programs. These programs exist in every U.S. state and territory and serve underrepresented populations through such major initiatives as adult basic education, adult secondary education (and GED preparation), and English language acquisition. These students are workers, consumers, voters, parents, grandparents, and members of every community. They have specific needs that are often overlooked in outreach activities. This presentation will describe the steps by which the Oregon Ocean Science and Math Collaborative program was developed. It is based on a partnership between the Oregon Department of Community Colleges and Workforce Development, Oregon State University College of Oceanic and Atmospheric Sciences, Oregon Sea Grant, and the OSU Hatfield Marine Science Center. It includes professional development through instructor institutes; teachers at sea and informal education opportunities; curriculum and web site development. Through the partnership described here, instructors in adult basic education programs participate in a yearlong experience in which they develop, test, and adapt innovative instructional strategies to meet the specific needs of adult learners. This, in turn, leads to new prospects for study in the areas of ocean science and math and introduces non-academic careers in marine science to a new community. Working directly with instructors, we have identified expertise level, instructional environment, instructor background and current teaching strategies used to address science literacy and numeracy goals of the adult learners in the State of Oregon. Preliminary evaluation of our ongoing project in meeting these goals will be discussed. These efforts contribute to national goals of science literacy for all, by providing

  7. Truth in basic biomedical science will set future mankind free.

    PubMed

    Ling, Gilbert N

    2011-01-01

    It is self-evident that continued wellbeing and prosperity of our species in time to come depends upon a steady supply of major scientific and technologic innovations. However, major scientific and technical innovations are rare. As a rule, they grow only in the exceptionally fertile minds of men and women, who have fully mastered the underlying basic sciences. To waken their interest in science at an early critical age and to nurture and enhance that interest afterward, good textbooks at all level of education that accurately portray the relevant up-to-date knowledge are vital. As of now, the field of science that offers by far the greatest promise for the future of humanity is the science of life at the most basic cell and below-cell level. Unfortunately, it is precisely this crucial part of the (standardized) biological textbooks for all high schools and colleges in the US and abroad that have become, so to speak, fossilized. As a result, generation after generation of (educated) young men and women have been and are still being force-fed as established scientific truth an obsolete membrane (pump) theory, which has been categorically disproved half a century ago (see Endnote 1.) To reveal this Trojan horse of a theory for what it really is demands the concerted efforts of many courageous individuals especially young biology teachers who take themselves and their career seriously. But even the most courageous and the most resourceful won't find the task easy. To begin with, they would find it hard to access the critical scientific knowledge, with which to convert the skeptic and to rally the friendly. For the wealth of mutually supportive evidence against the membrane (pump) theory are often hidden in inaccessible publications and/or in languages other than English. To overcome this seemingly trivial but in fact formidable obstacle and to reveal the beauty and coherence of the existing but untaught truth, I put together in this small package a collection of the

  8. Learning basic science alongside veterinary students: creating an interactive classroom.

    PubMed

    Brown, Scott A

    2004-01-01

    Dr. Scott Brown's dedication and contribution to the instructional programs of the University of Georgia College of Veterinary Medicine have been exceptionally meritorious. In the last eight years, he has served with the leadership among faculty in the design and approval of a new curriculum, and as chair of the curriculum committee he led the College in its implementation. Throughout this period his research productivity, mentorship of professional and graduate students, and professional development continued. Dr. Brown instills energy, broadens learning experiences from personal and professional development to basic science, and, in all probability, provides positive, life-changing experiences for his students. I am very pleased that he was recognized in 2003 with the Carl J. Norden National Distinguished Teacher Award.

  9. Corneal gene therapy: basic science and translational perspective.

    PubMed

    Mohan, Rajiv R; Rodier, Jason T; Sharma, Ajay

    2013-07-01

    Corneal blindness is the third leading cause of blindness worldwide. Gene therapy is an emerging technology for corneal blindness due to the accessibility and immune-privileged nature of the cornea, ease of vector administration and visual monitoring, and ability to perform frequent noninvasive corneal assessment. Vision restoration by gene therapy is contingent upon vector and mode of therapeutic gene introduction into targeted cells/tissues. Numerous efficacious vectors, delivery techniques, and approaches have evolved in the last decade for developing gene-based interventions for corneal diseases. Maximizing the potential benefits of gene therapy requires efficient and sustained therapeutic gene expression in target cells, low toxicity, and a high safety profile. This review describes the basic science associated with many gene therapy vectors and the present progress of gene therapy carried out for various ocular surface disorders and diseases.

  10. Corneal Gene Therapy: Basic Science and Translational Perspective

    PubMed Central

    Mohan, Rajiv R.; Rodier, Jason T.; Sharma, Ajay

    2013-01-01

    Corneal blindness is the third leading cause of blindness worldwide. Gene therapy is an emerging technology for corneal blindness due to the accessibility and immune-privileged nature of the cornea, ease of vector administration and visual monitoring, and ability to perform frequent noninvasive corneal assessment. Vision restoration by gene therapy is contingent upon vector and mode of therapeutic gene introduction into targeted cells/tissues. Numerous efficacious vectors, delivery techniques, and approaches have evolved in last decade for developing gene-based interventions for corneal diseases. Maximizing the potential benefits of gene therapy requires efficient and sustained therapeutic gene expression in target cells, low toxicity, and a high safety profile. This review describes the basic science associated with many gene therapy vectors and the present progress of gene therapy carried out for various ocular surface disorders and diseases. PMID:23838017

  11. Basic research needs to assure a secure energy future. A report from the Basic Energy Sciences Advisory Committee

    SciTech Connect

    2003-02-01

    This report has highlighted many of the possible fundamental research areas that will help our country avoid a future energy crisis. The report may not have adequately captured the atmosphere of concern that permeated the discussions at the workshop. The difficulties facing our nation and the world in meeting our energy needs over the next several decades are very challenging. It was generally felt that traditional solutions and approaches will not solve the total energy problem. Knowledge that does not exist must be obtained to address both the quantity of energy needed to increase the standard of living world-wide and the quality of energy generation needed to preserve the environment. In terms of investments, it was clear that there is no single research area that will secure the future energy supply. A diverse range of economic energy sources will be required--and a broad range of fundamental research is needed to enable these. Many of the issues fall into the traditional materials and chemical sciences research areas, but with specific emphasis on understanding mechanisms, energy related phenomena, and pursuing novel directions in, for example, nanoscience and integrated modeling. An important result from the discussions, which is hopefully apparent from the brief presentations above, is that the problems that must be dealt with are truly multidisciplinary. This means that they require the participation of investigators with different skill sets. Basic science skills have to be complemented by awareness of the overall nature of the problem in a national and world context, and with knowledge of the engineering, design, and control issues in any eventual solution. It is necessary to find ways in which this can be done while still preserving the ability to do first-class basic science. The traditional structure of research, with specific disciplinary groupings, will not be sufficient. This presents great challenges and opportunities for the funders of the

  12. Alternative Methods by Which Basic Science Pharmacy Faculty Can Relate to Clinical Practice.

    ERIC Educational Resources Information Center

    Kabat, Hugh F.; And Others

    1982-01-01

    A panel of pharmacy faculty ranked a broad inventory of basic pharmaceutical science topics in terms of their applicability to clinical pharmacy practice. The panel concluded that basic pharmaceutical sciences are essentially applications of foundation areas in biological, physical, and social sciences. (Author/MLW)

  13. The Reorganization of Basic Science Departments in U.S. Medical Schools, 1980-1999.

    ERIC Educational Resources Information Center

    Mallon, William T.; Biebuyck, Julien F.; Jones, Robert F.

    2003-01-01

    Constructed a longitudinal database to examine how basic science departments have been reorganized at U.S. medical schools. Found that there were fewer basic science departments in the traditional disciplines of anatomy, biochemistry, microbiology, pharmacology, and physiology in 1999 than in 1980. But as biomedical science has developed in an…

  14. 75 FR 65363 - Basic Behavioral and Social Science Opportunity Network (OppNet)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... HUMAN SERVICES National Institutes of Health Basic Behavioral and Social Science Opportunity Network... promote and publicize the Basic Behavioral and Social Science Opportunity Network (OppNet) initiative... Behavioral and Social Science Opportunity Network (OppNet) is a trans-NIH initiative to expand the...

  15. A Case Study on Science Teacher Leadership to Address Diversity and Equity Through Professional Development

    NASA Astrophysics Data System (ADS)

    Doraiswamy, Nithya

    This qualitative case study focused on the multifaceted issue of exploring science teacher leaders understanding and addressing of issues of diversity and equity with peers through professional development. The purpose of the study was to highlight the opportunities and barriers to the addressing of issues of diversity and equity through the work of a community of teachers leaders in science professional development. To frame this study, the researcher drew from the interdisciplinary field of multicultural education, transformative learning, and teacher leadership. In drawing out the connections from these vast bodies of literature, the study speaks to the need of both, creating teacher leaders in science education who are capable of meeting the twin demands of excellence and equity, and also attending to the challenges in the professional learning continuums of teachers leaders and their peers towards addressing issues of diversity and equity in science education.

  16. Basic Research Policy of the Department of Defense: Report of the Defense Science Board Task Force

    DTIC Science & Technology

    1968-02-20

    Classification) Basic Research Policy of the Department of Defense, Report of the Defense Science Board Task Force, UNCLASSIFIED 12 PERSONAL AUTHOR(S) N/A...obsolete. SECURITY CLASSIFICATION OF THIS PAGE — In wcnssrnw BASIC RESEARCH POLICY OF THE DEPARTMENT OF DEFENSE Report of the Defense Science Board Task...BOARD SUBJECT: Report of Task Force on Basic Research Policy The Task Force of the Defense Science Board, appointed at the request of the

  17. The HelCat basic plasma science device

    NASA Astrophysics Data System (ADS)

    Gilmore, M.; Lynn, A. G.; Desjardins, T. R.; Zhang, Y.; Watts, C.; Hsu, S. C.; Betts, S.; Kelly, R.; Schamiloglu, E.

    2015-01-01

    The Helicon-Cathode(HelCat) device is a medium-size linear experiment suitable for a wide range of basic plasma science experiments in areas such as electrostatic turbulence and transport, magnetic relaxation, and high power microwave (HPM)-plasma interactions. The HelCat device is based on dual plasma sources located at opposite ends of the 4 m long vacuum chamber - an RF helicon source at one end and a thermionic cathode at the other. Thirteen coils provide an axial magnetic field B >= 0.220 T that can be configured individually to give various magnetic configurations (e.g. solenoid, mirror, cusp). Additional plasma sources, such as a compact coaxial plasma gun, are also utilized in some experiments, and can be located either along the chamber for perpendicular (to the background magnetic field) plasma injection, or at one of the ends for parallel injection. Using the multiple plasma sources, a wide range of plasma parameters can be obtained. Here, the HelCat device is described in detail and some examples of results from previous and ongoing experiments are given. Additionally, examples of planned experiments and device modifications are also discussed.

  18. Basic science behind the cardiovascular benefits of exercise.

    PubMed

    Wilson, Mathew G; Ellison, Georgina M; Cable, N Tim

    2016-01-01

    Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause mortality, with increases in cardiorespiratory fitness associated with corresponding decreases in CV disease risk. The effects of exercise upon the myocardium and vascular system are dependent upon the frequency, intensity and duration of the exercise itself. Following a prolonged period (≥6 months) of regular intensive exercise in previously untrained individuals, resting and submaximal exercising heart rates are typically 5-20 beats lower, with an increase in stroke volume of ∼20% and enhanced myocardial contractility. Structurally, all four heart chambers increase in volume with mild increases in wall thickness, resulting in greater cardiac mass due to increased myocardial cell size. With this in mind, the present paper aims to review the basic science behind the CV benefits of exercise. Attention will be paid to understanding (1) the relationship between exercise and cardiac remodelling; (2) the cardiac cellular and molecular adaptations in response to exercise, including the examination of molecular mechanisms of physiological cardiac growth and applying these mechanisms to identify new therapeutic targets to prevent or reverse pathological remodelling and heart failure; and (3) vascular adaptations in response to exercise. Finally, this review will briefly examine how to optimise the CV benefits of exercise by considering how much and how intense exercise should be.

  19. Basic science behind the cardiovascular benefits of exercise.

    PubMed

    Wilson, Mathew G; Ellison, Georgina M; Cable, N Tim

    2015-05-15

    Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause mortality, with increases in cardiorespiratory fitness associated with corresponding decreases in CV disease risk. The effects of exercise upon the myocardium and vascular system are dependent upon the frequency, intensity and duration of the exercise itself. Following a prolonged period (≥6 months) of regular intensive exercise in previously untrained individuals, resting and submaximal exercising heart rates are typically 5-20 beats lower, with an increase in stroke volume of ∼20% and enhanced myocardial contractility. Structurally, all four heart chambers increase in volume with mild increases in wall thickness, resulting in greater cardiac mass due to increased myocardial cell size. With this in mind, the present paper aims to review the basic science behind the CV benefits of exercise. Attention will be paid to understanding (1) the relationship between exercise and cardiac remodelling; (2) the cardiac cellular and molecular adaptations in response to exercise, including the examination of molecular mechanisms of physiological cardiac growth and applying these mechanisms to identify new therapeutic targets to prevent or reverse pathological remodelling and heart failure; and (3) vascular adaptations in response to exercise. Finally, this review will briefly examine how to optimise the CV benefits of exercise by considering how much and how intense exercise should be.

  20. Myocardial ischemia reperfusion injury: from basic science to clinical bedside.

    PubMed

    Frank, Anja; Bonney, Megan; Bonney, Stephanie; Weitzel, Lindsay; Koeppen, Michael; Eckle, Tobias

    2012-09-01

    Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the heart causes an imbalance between oxygen demand and supply, named ischemia (from the Greek isch, restriction; and haema, blood), resulting in damage or dysfunction of the cardiac tissue. Instinctively, early and fast restoration of blood flow has been established to be the treatment of choice to prevent further tissue injury. Indeed, the use of thrombolytic therapy or primary percutaneous coronary intervention is the most effective strategy for reducing the size of a myocardial infarct and improving the clinical outcome. Unfortunately, restoring blood flow to the ischemic myocardium, named reperfusion, can also induce injury. This phenomenon was therefore termed myocardial ischemia reperfusion injury. Subsequent studies in animal models of acute myocardial infarction suggest that myocardial ischemia reperfusion injury accounts for up to 50% of the final size of a myocardial infarct. Consequently, many researchers aim to understand the underlying molecular mechanism of myocardial ischemia reperfusion injury to find therapeutic strategies ultimately reducing the final infarct size. Despite the identification of numerous therapeutic strategies at the bench, many of them are just in the process of being translated to bedside. The current review discusses the most striking basic science findings made during the past decades that are currently under clinical evaluation, with the ultimate goal to treat patients who are suffering from myocardial ischemia reperfusion-associated tissue injury.

  1. Cancer Pharmacogenomics: Integrating Discoveries in Basic, Clinical and Population Sciences to Advance Predictive Cancer Care

    Cancer.gov

    Cancer Pharmacogenomics: Integrating Discoveries in Basic, Clinical and Population Sciences to Advance Predictive Cancer Care, a 2010 workshop sponsored by the Epidemiology and Genomics Research Program.

  2. PNNL Highlights for the Office of Basic Energy Sciences (July 2013-July 2014)

    SciTech Connect

    Anderson, Benjamin; Warren, Pamela M.; Manke, Kristin L.

    2014-08-13

    This report includes research highlights of work funded in part or whole by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences as well as selected leadership accomplishments.

  3. Beyond Evolution: Addressing Broad Interactions between Science and Religion in Science Teacher Education

    ERIC Educational Resources Information Center

    Shane, Joseph W.; Binns, Ian C.; Meadows, Lee; Hermann, Ronald S.; Benus, Matthew J.

    2016-01-01

    Science and religion are two indisputably profound and durable cultural forces with a complex history of interaction. As ASTE members are aware, these interactions often manifest themselves in classrooms and in the surrounding communities. In this essay, we encourage science teacher educators to broaden their perspectives of science-religion…

  4. The Brown Superfund Basic Research Program: A Multistakeholder Partnership Addresses Real-World Problems in Contaminated Communities

    PubMed Central

    Senier, Laura; Hudson, Benjamin; Fort, Sarah; Hoover, Elizabeth; Tillson, Rebecca; Brown, Phil

    2008-01-01

    The NIEHS funds several basic and applied research programs, many of which also require research translation or outreach. This paper reports on a project by the Brown University Superfund Basic Research Program (SBRP), in which outreach and research translation teams collaborated with state regulatory agency personnel and community activists on a legislative initiative to mitigate the financial impacts of living in a contaminated community. The Environmentally Compromised Home Ownership (ECHO) program makes home equity loans of up to $25,000 available to qualified applicants. This collaboration provides a case study in community engagement and demonstrates how research translation and outreach activities that are clearly differentiated yet well integrated can improve a suite of basic and applied research. Although engaging diverse constituencies can be difficult, community-engaged translation and outreach have the potential to make research findings more useful to communities, address some of the social impacts of contamination, and empower stakeholders to pursue their individual and collectively-held goals for remediation. The NIEHS has recently renewed its commitment to community-engaged research and advocacy, making this an optimal time to reflect on how basic research programs that engage stakeholders through research translation and outreach can add value to the overall research enterprise. PMID:18677987

  5. Japanese medical students' interest in basic sciences: a questionnaire survey of a medical school in Japan.

    PubMed

    Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji

    2013-01-01

    The number of physicians engaged in basic sciences and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study investigated medical students' interest in basic sciences in efforts to recruit talent. A questionnaire distributed to 501 medical students in years 2 to 6 of Juntendo University School of Medicine inquired about sex, grade, interest in basic sciences, interest in research, career path as a basic science physician, faculties' efforts to encourage students to conduct research, increases in the number of lectures, and practical training sessions on research. Associations between interest in basic sciences and other variables were examined using χ(2) tests. From among the 269 medical students (171 female) who returned the questionnaire (response rate 53.7%), 24.5% of respondents were interested in basic sciences and half of them considered basic sciences as their future career. Obstacles to this career were their original aim to become a clinician and concerns about salary. Medical students who were likely to be interested in basic sciences were fifth- and sixth-year students, were interested in research, considered basic sciences as their future career, considered faculties were making efforts to encourage medical students to conduct research, and wanted more research-related lectures. Improving physicians' salaries in basic sciences is important for securing talent. Moreover, offering continuous opportunities for medical students to experience research and encouraging advanced-year students during and after bedside learning to engage in basic sciences are important for recruiting talent.

  6. Science Serving the Nation: The Impact of Basic Research

    SciTech Connect

    None, None

    2012-01-01

    Impacts: The BES program supports basic research that underpins a broad range of energy technologies. Research in materials sciences and engineering leads to the development of materials that improve the efficiency, economy, environmental acceptability, and safety of energy generation, conversion, transmission, storage, and use. For example, advances in superconductivity have been introduced commercially in a number of demonstration projects around the country. Improvements in alloy design for high temperature applications are used in commercial furnaces and in green technologies such as lead-free solder. Research in chemistry has led to advances such as efficient combustion systems with reduced emissions of pollutants; new solar photoconversion processes; improved catalysts for the production of fuels and chemicals; and better separations and analytical methods for applications in energy processes, environmental remediation, and waste management. Research in geosciences results in advanced monitoring and measurement techniques for reservoir definition and an understanding of the fluid dynamics of complex fluids through porous and fractured subsurface rock. Research in the molecular and biochemical nature of photosynthesis aids the development of solar photo-energy conversion. The BES program also plays a major role in enabling the nanoscale revolution. The importance of nanoscience to future energy technologies is clearly reflected by the fact that all of the elementary steps of energy conversion (e.g., charge transfer, molecular rearrangement, and chemical reactions) take place on the nanoscale. The development of new nanoscale materials, as well as the methods to characterize, manipulate, and assemble them, create an entirely new paradigm for developing new and revolutionary energy technologies.

  7. Science Awareness and Science Literacy through the Basic Physics Course: Physics with a bit of Metaphysics?

    NASA Astrophysics Data System (ADS)

    Rusli, Aloysius

    2016-08-01

    Until the 1980s, it is well known and practiced in Indonesian Basic Physics courses, to present physics by its effective technicalities: The ideally elastic spring, the pulley and moving blocks, the thermodynamics of ideal engine models, theoretical electrostatics and electrodynamics with model capacitors and inductors, wave behavior and its various superpositions, and hopefully closed with a modern physics description. A different approach was then also experimented with, using the Hobson and Moore texts, stressing the alternative aim of fostering awareness, not just mastery, of science and the scientific method. This is hypothesized to be more in line with the changed attitude of the so-called Millenials cohort who are less attentive if not interested, and are more used to multi-tasking which suits their shorter span of attention. The upside is increased awareness of science and the scientific method. The downside is that they are getting less experience of the scientific method which intensely bases itself on critical observation, analytic thinking to set up conclusions or hypotheses, and checking consistency of the hypotheses with measured data. Another aspect is recognition that the human person encompasses both the reasoning capacity and the mental- spiritual-cultural capacity. This is considered essential, as the world grows even smaller due to increased communication capacity, causing strong interactions, nonlinear effects, and showing that value systems become more challenging and challenged due to physics / science and its cosmology, which is successfully based on the scientific method. So students should be made aware of the common basis of these two capacities: the assumptions, the reasoning capacity and the consistency assumption. This shows that the limits of science are their set of basic quantifiable assumptions, and the limits of the mental-spiritual-cultural aspects of life are their set of basic metaphysical (non-quantifiable) assumptions. The

  8. Back to Basics for Science Teachers in Rural India.

    ERIC Educational Resources Information Center

    Waldron, Nick

    1998-01-01

    Describes how practical science can be taught using locally-collected junk materials and encourages a new approach to science teaching in rural India. Emphasizes science relevant to the villages to which children will return to when they leave school. (DDR)

  9. The Role of Basic Sciences in Patient Care and Clinical Teaching.

    ERIC Educational Resources Information Center

    White, Raymond P.

    1986-01-01

    More can be done to incorporate basic biological science into clinical dental teaching, including increased early basic science instruction by clinical faculty, establishment of departments of oral biology, the grand rounds format, case presentation in clinical settings, and continuing education involving practicing dentists and dental students.…

  10. Progress in the utilization of high-fidelity simulation in basic science education.

    PubMed

    Helyer, Richard; Dickens, Peter

    2016-06-01

    High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress.

  11. Progress in the Utilization of High-Fidelity Simulation in Basic Science Education

    ERIC Educational Resources Information Center

    Helyer, Richard; Dickens, Peter

    2016-01-01

    High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress.

  12. A Simulation for Teaching the Basic and Clinical Science of Fluid Therapy

    ERIC Educational Resources Information Center

    Rawson, Richard E.; Dispensa, Marilyn E.; Goldstein, Richard E.; Nicholson, Kimberley W.; Vidal, Noni Korf

    2009-01-01

    The course "Management of Fluid and Electrolyte Disorders" is an applied physiology course taught using lectures and paper-based cases. The course approaches fluid therapy from both basic science and clinical perspectives. While paper cases provide a basis for application of basic science concepts, they lack key components of genuine clinical…

  13. Acquisition of Basic Science Process Skills among Malaysian Upper Primary Students

    ERIC Educational Resources Information Center

    Ong, Eng Tek; Ramiah, Puspa; Ruthven, Kenneth; Salleh, Sabri Mohd; Yusuff, Nik Azmah Nik; Mokhsein, Siti Eshah

    2015-01-01

    This study aims to determine whether there are significant differences in the acquisition of basic science process skills by gender, school location and by grade levels among upper primary school students. Using an established 36-item Basic Science Process Skills test that assesses the skills of observing, communicating, classifying, measuring,…

  14. Basic Research Needs for Advanced Nuclear Systems. Report of the Basic Energy Sciences Workshop on Basic Research Needs for Advanced Nuclear Energy Systems, July 31-August 3, 2006

    SciTech Connect

    Roberto, J.; Diaz de la Rubia, T.; Gibala, R.; Zinkle, S.; Miller, J.R.; Pimblott, S.; Burns, C.; Raymond, K.; Grimes, R.; Pasamehmetoglu, K.; Clark, S.; Ewing, R.; Wagner, A.; Yip, S.; Buchanan, M.; Crabtree, G.; Hemminger, J.; Poate, J.; Miller, J.C.; Edelstein, N.; Fitzsimmons, T.; Gruzalski, G.; Michaels, G.; Morss, L.; Peters, M.; Talamini, K.

    2006-10-01

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  15. Development and Validation of the Life Sciences Assessment: A Measure of Preschool Children's Conceptions of Basic Life Sciences

    ERIC Educational Resources Information Center

    Maherally, Uzma Nooreen

    2014-01-01

    The purpose of this study was to develop and validate a science assessment tool termed the Life Sciences Assessment (LSA) in order to assess preschool children's conceptions of basic life sciences. The hypothesis was that the four sub-constructs, each of which can be measured through a series of questions on the LSA, will make a significant…

  16. President Barack Obama addresses the 146th Annual Meeting of the National Academy of Sciences

    PubMed Central

    2009-01-01

    On April 27, 2009, President Barack Obama addressed members of the National Academy of Sciences (NAS) gathered at its 146th annual meeting in Washington, D.C. In his speech, the president shared his plans to give science and technology a central role in the nation's future and an immediate place in America's economic renewal. He outlined steps he is taking to increase research spending, achieve energy independence, and improve science education. Included was what Mr. Obama cited as the largest commitment to scientific research in American history—devoting more than 3% of our gross domestic product to research and development. “Next, we are restoring science to its rightful place,” Mr. Obama told a packed NAS auditorium audience. “Under my administration, the days of science taking a backseat to ideology are over.” He appealed to scientists' sense of personal responsibility to reach and educate young Americans: “I want to challenge you to use your love and knowledge of science to spark a sense of wonder and excitement in a new generation.” President Obama was welcomed to the National Academy of Sciences by President Ralph J. Cicerone and John P. Holdren, Assistant to the President for Science and Technology and Director of the White House Office of Science and Technology Policy. The following is a transcript of that speech.* PMID:19502426

  17. President Barack Obama addresses the 146th annual meeting of the National Academy of Sciences.

    PubMed

    2009-06-16

    On April 27, 2009, President Barack Obama addressed members of the National Academy of Sciences (NAS) gathered at its 146th annual meeting in Washington, D.C. In his speech, the president shared his plans to give science and technology a central role in the nation's future and an immediate place in America's economic renewal. He outlined steps he is taking to increase research spending, achieve energy independence, and improve science education. Included was what Mr. Obama cited as the largest commitment to scientific research in American history-devoting more than 3% of our gross domestic product to research and development. "Next, we are restoring science to its rightful place," Mr. Obama told a packed NAS auditorium audience. "Under my administration, the days of science taking a backseat to ideology are over." He appealed to scientists' sense of personal responsibility to reach and educate young Americans: "I want to challenge you to use your love and knowledge of science to spark a sense of wonder and excitement in a new generation." President Obama was welcomed to the National Academy of Sciences by President Ralph J. Cicerone and John P. Holdren, Assistant to the President for Science and Technology and Director of the White House Office of Science and Technology Policy. The following is a transcript of that speech.

  18. Addressing Controversies in Science Education: A Pragmatic Approach to Evolution Education

    ERIC Educational Resources Information Center

    Hildebrand, David; Bilica, Kimberly; Capps, John

    2008-01-01

    Science education controversies typically prove more intractable than those in scientific research because they involve a wider range of considerations (e.g., epistemic, social, ethical, political, and religious). How can educators acknowledge central issues in a controversy (such as evolution)? How can such problems be addressed in a way that is…

  19. Identifying and Addressing Student Difficulties and Misconceptions: Examples from Physics and from Materials Science and Engineering

    ERIC Educational Resources Information Center

    Rosenblatt, Rebecca

    2012-01-01

    Here I present my work identifying and addressing student difficulties with several materials science and physics topics. In the first part of this thesis, I present my work identifying student difficulties and misconceptions about the directional relationships between net force, velocity, and acceleration in one dimension. This is accomplished…

  20. Race and Science: Using a Comprehensive Interdisciplinary Approach To Address Complex Issues.

    ERIC Educational Resources Information Center

    Eisen, Arri; Cimino, Ashley; Aparicio, Hugo; Marsteller, Patricia; Kushner, Howard

    2003-01-01

    Describes an interdisciplinary approach that integrates the strengths of a research and teaching institution to address issues in a complex problem: the study of race, science, and health. The model involved a feedback loop among two undergraduate courses and a weekly seminar. (SLD)

  1. The Relationship between Immediate Relevant Basic Science Knowledge and Clinical Knowledge: Physiology Knowledge and Transthoracic Echocardiography Image Interpretation

    ERIC Educational Resources Information Center

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-01-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent…

  2. The Impact of Hands-On-Approach on Student Academic Performance in Basic Science and Mathematics

    ERIC Educational Resources Information Center

    Ekwueme, Cecilia O.; Ekon, Esther E.; Ezenwa-Nebife, Dorothy C.

    2015-01-01

    Children can learn mathematics and sciences effectively even before being exposed to formal school curriculum if basic Mathematics and Sciences concepts are communicated to them early using activity oriented (Hands-on) method of teaching. Mathematics and Science are practical and activity oriented and can best be learnt through inquiry (Okebukola…

  3. Science Teachers' Use of Mass Media to Address Socio-Scientific and Sustainability Issues

    NASA Astrophysics Data System (ADS)

    Klosterman, Michelle L.; Sadler, Troy D.; Brown, Julie

    2012-01-01

    The currency, relevancy and changing nature of science makes it a natural topic of focus for mass media outlets. Science teachers and students can capitalize on this wealth of scientific information to explore socio-scientific and sustainability issues; however, without a lens on how those media are created and how representations of science are constructed through media, the use of mass media in the science classroom may be risky. Limited research has explored how science teachers naturally use mass media to explore scientific issues in the classroom or how mass media is used to address potential overlaps between socio-scientific-issue based instruction and education for sustainability. This naturalistic study investigated the reported and actual classroom uses of mass media by secondary science teachers' to explore socio-scientific and sustainability issues as well as the extent to which their instructional approaches did or did not overlap with frameworks for SSI-based instruction, education for sustainability, and media literacy education. The results of this study suggest that secondary science teachers use mass media to explore socio-scientific and sustainability issues, but their use of frameworks aligned with SSI-based, education for sustainability, and media literacy education was limited. This paper provides suggestions for how we, as science educators and researchers, can advance a teaching and learning agenda for encouraging instruction that more fully utilizes the potential of mass media to explore socio-scientific issues in line with perspectives from education for sustainability.

  4. Addressing conflicts of interest in the research paper: a societal demand in contemporary science?

    PubMed Central

    Vasconcelos, S.M.R.; Cassimiro, M.C.; Martins, M.F.M.; Palácios, M.

    2013-01-01

    In the last decade, dialogue between science and society has found a forum in an increasing number of publications on topics such as public engagement with science and public trust in science. Concerning the latter, issues that include cases of research misconduct, accountability in research, and conflicts of interest (COIs) have shaped global discussions on the communication of science. In the publication setting, the perception that hiding COIs and/or not managing them well may affect public trust in the research record has grown among editors. We conducted a search for editorials addressing COIs between 1989 and 2011, using four major databases: Medline/PubMed, Embase, Scopus, and Web of Knowledge. We explored the content of these editorials and the relationship they established between COIs and the public trust in science. Our results demonstrate that the relationship between disclosure of COIs and public trust in science has become a major concern among editors. We, thus, argue that COIs should be discussed more openly and frequently in graduate courses in the sciences, around the globe, not only in biomedical but also in non-biomedical areas. This is a critical issue in contemporary science, as graduate students are the future voices and decision-makers of the research community. Therefore, COIs, especially in the broader context of science and society, merit closer attention from policymakers, researchers, and educators. At times of great expectations for public engagement with science, mishandling of COIs may have undesirable consequences for public engagement with science and confidence in the scientific endeavor. PMID:24345908

  5. Basic science research and education: a priority for training and capacity building in developing countries.

    PubMed

    Deckelbaum, Richard J; Ntambi, James M; Wolgemuth, Debra J

    2011-09-01

    This article provides evidence that basic science research and education should be key priorities for global health training, capacity building, and practice. Currently, there are tremendous gaps between strong science education and research in developed countries (the North) as compared to developing countries (the South). In addition, science research and education appear as low priorities in many developing countries. The need to stress basic science research beyond the typical investment of infectious disease basic service and research laboratories in developing areas is significant in terms of the benefits, not only to education, but also for economic strengthening and development of human resources. There are some indications that appreciation of basic science research education and training is increasing, but this still needs to be applied more rigorously and strengthened systematically in developing countries.

  6. Basic science and energy research sector profile: Background for the National Energy Strategy

    SciTech Connect

    March, F.; Ashton, W.B.; Kinzey, B.R.; McDonald, S.C.; Lee, V.E.

    1990-11-01

    This Profile report provides a general perspective on the role of basic science in the spectrum of research and development in the United States, and basic research's contributions to the goals of the National Energy Strategy (NES). It includes selected facts, figures, and analysis of strategic issues affecting the future of science in the United States. It is provided as background for people from government, the private sector, academia, and the public, who will be reviewing the NES in the coming months; and it is intended to serve as the basis for discussion of basic science issues within the context of the developing NES.

  7. Teaching Basic Science Environmentally, The Concept: The cell is basic unit of structure of most organisms.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1985-01-01

    Suggests simple ways to introduce students to the concept that the cell is the basic unit of structure of most organisms. Mentions materials for microscope study that are readily available and easy to handle, e.g., membranes from between the scales of the onion bulb, thin-leaved plants, pond water, and pollen. (JHZ)

  8. DOI Climate Science Centers--Regional science to address management priorities

    USGS Publications Warehouse

    O'Malley, Robin

    2012-01-01

    Our Nation's lands, waters, and ecosystems and the living and cultural resources they contain face myriad challenges from invasive species, the effects of changing land and water use, habitat fragmentation and degradation, and other influences. These challenges are compounded by increasing influences from a changing climate—higher temperatures, increasing droughts, floods, and wildfires, and overall increasing variability in weather and climate. The Department of the Interior (DOI) has established eight regional Climate Science Centers (CSC) (fig. 1) that will provide scientific information and tools to natural and cultural resource managers as they plan for conserving these resources in a changing world. The U.S. Geological Survey (USGS) National Climate Change and Wildlife Science Center (NCCWSC) is managing the CSCs on behalf of the DOI.

  9. Obama Emphasizes Science and Innovation in State of the Union Address

    NASA Astrophysics Data System (ADS)

    Tretkoff, Ernie

    2011-02-01

    U.S. president Barack Obama emphasized innovation and competitiveness in his State of the Union address on 25 January. He also raised science and technology early in the hour-long speech, noting that nations like China and India are focusing on math and science education and investing in research and technology. To be competitive with those countries, “we need to out-innovate, out-educate, and out-build the rest of the world,” Obama said. “The first step in winning the future is encouraging American innovation.”

  10. The Integration of Nutrition Education in the Basic Biomedical Sciences

    ERIC Educational Resources Information Center

    Raw, Isaias

    1977-01-01

    At the Center for Biomedical Education at the City University of New York, nutrition is integrated into the chemistry-biochemistry sequence of a six-year B.S.-M.D. program. Students perform an actual analysis of a sample of their own food, learning basic techniques and concepts, and also carry on experiments with rats on other diets. (Editor/LBH)

  11. Teaching Basic Classification through an Elementary Science Unit on Food.

    ERIC Educational Resources Information Center

    Schubert, Nancy A.

    Five lesson plans are included in this unit designed to teach basic classification skills through the study of food. Each lesson plan contains an objective, list of materials needed, statement of the lesson problem, instructional strategies, learning outcomes, and evaluation method(s). Objectives of the lessons include: (1) grouping common animals…

  12. Dilemmas with Dilemmas...Exploring the Suitability of Dilemma Stories as a Way of Addressing Ethical Issues in Science Education.

    ERIC Educational Resources Information Center

    Settelmaier, Elisabeth

    Traditionally, many science educators have taught science without addressing ethical questions. However, the inclusion of moral discourse in science teaching may help educators to bring to the fore problematic issues in relation to science, and it may offer an opportunity for students to practice their future engagement in the public discourse…

  13. Using Soils to Teach Basic Concepts in Science and Art

    NASA Astrophysics Data System (ADS)

    Lindbo, David L.; Kozlowski, Deborah; Robinson, Clay; Chapman, Susan

    2014-05-01

    Teaching primary and secondary school students (K-12) about science and art, although absolutely critical, can be difficult. Teachers have specific standards or subject matters that they are required to cover and often soils and soil science is not included in that list. We have struggled with ways to bring soil science information to the larger audience as the direct approach meets with resistance due to the time commitments to other standards. Our approach now is to use soils as a media or vehicle to teach key concepts in broad subject areas. We have developed several lesson plans in science, geography, math and art that focus on a concept but use soils to convey it. For example students make "mini" monoliths of a state soil. During this exercise students need to use skills in geography to find where their state soil occurs in their state and in the country. They need to understand colors in order to choose the correct colors to use to make their monolith. Finally, they must understand how scales work in order to make the monolith accurate in terms of horizon depths. Throughout the exercise discussion on my certain colors occur in the soil can be discussed. This discussion can lead to a qualitative understanding of chemistry and biology. This presentation will demonstrate this lesson and several others that have been developed and available through the Soil Science Society of America's K12 Education Committee.

  14. Mi-STAR: Designing Integrated Science Curriculum to Address the Next Generation Science Standards and Their Foundations

    NASA Astrophysics Data System (ADS)

    Gochis, E. E.; Huntoon, J. E.

    2015-12-01

    Mi-STAR (Michigan Science Teaching and Assessment Reform, http://mi-star.mtu.edu/) was funded by the Herbert H. and Grace A. Dow Foundation to reform K-12 science education to present science as an integrated body of knowledge that is applied to address societal issues. To achieve this goal, Mi-STAR is developing an integrated science curriculum for the middle grades that will be aligned with the Next Generation Science Standards (NGSS). Similar to the geosciences, the curriculum requires the integration of science, engineering and math content to explore 21st-century issues and demonstrates how these concepts can be used in service of society. The curriculum is based on the Mi-STAR Unit Specification Chart which pairs interdisciplinary themes with bundled NGSS Performance Expectations. Each unit is developed by a collaborative team of K-12 teachers, university STEM content experts and science education experts. Prior to developing a unit, each member on the team attends the on-line Mi-STAR Academy, completing 18+ hours of professional development (PD). This on-line PD program familiarizes teachers and experts with necessary pedagogical and content background knowledge, including NGSS and three-dimensional learning. With this background, teams use a staged, backwards design process to craft a multi-week unit based on a series of performance based tasks, or 'challenges' that engage students in actively doing science and engineering. Each unit includes Disciplinary Core Ideas from multiple disciplines, which focus on local and familiar examples that demonstrate the relevance of science in student's lives. Performance-based assessments are interwoven throughout the unit. Mi-STAR units will go through extensive pilot testing in several school districts across the state of Michigan. Additionally, the Mi-STAR program will develop teacher professional development programs to support implementation of the curriculum and design a pre-service teacher program in integrated

  15. Funding the Foundation: Basic Science at the Crossroads

    ERIC Educational Resources Information Center

    Hughes, Kent, Ed.; Sha, Lynn, Ed.

    2006-01-01

    These proceedings from a conference with leading experts examines the hugely successful American model of technological and scientific innovation. They stress the critical importance of government funding of physical science for the realms of national security, education, and industry. Kent Hughes and Frederick M. Bush, both of the Woodrow Wilson…

  16. Strengthening Faculty Recruitment for Health Professions Training in Basic Sciences in Zambia

    PubMed Central

    Simuyemba, Moses; Talib, Zohray; Michelo, Charles; Mutale, Wilbroad; Zulu, Joseph; Andrews, Ben; Katubulushi, Max; Njelesani, Evariste; Bowa, Kasonde; Maimbolwa, Margaret; Mudenda, John; Mulla, Yakub

    2014-01-01

    Zambia is facing a crisis in its human resources for health (HRH), with deficits in the number and skill mix of health workers. The University of Zambia School of Medicine (UNZA SOM) was the only medical school in the country for decades, but recently it was joined by three new medical schools—two private and one public. In addition to expanding medical education, the government has also approved several allied health programs, including pharmacy, physiotherapy, biomedical sciences, and environmental health. This expansion has been constrained by insufficient numbers of faculty. Through a grant from the Medical Education Partnership Initiative (MEPI), UNZA SOM has been investing in ways to address faculty recruitment, training, and retention. The MEPI-funded strategy involves directly sponsoring a cohort of faculty at UNZA SOM during the five-year grant, as well as establishing more than a dozen new master’s programs, with the goal that all sponsored faculty are locally trained and retained. Because the issue of limited basic science faculty plagues medical schools throughout Sub-Saharan Africa, this strategy of using seed funding to build sustainable local capacity to recruit, train, and retain faculty could be a model for the region. PMID:25072591

  17. Strengthening faculty recruitment for health professions training in basic sciences in Zambia.

    PubMed

    Simuyemba, Moses; Talib, Zohray; Michelo, Charles; Mutale, Wilbroad; Zulu, Joseph; Andrews, Ben; Nzala, Selestine; Katubulushi, Max; Njelesani, Evariste; Bowa, Kasonde; Maimbolwa, Margaret; Mudenda, John; Mulla, Yakub

    2014-08-01

    Zambia is facing a crisis in its human resources for health, with deficits in the number and skill mix of health workers. The University of Zambia School of Medicine (UNZA SOM) was the only medical school in the country for decades, but recently it was joined by three new medical schools--two private and one public. In addition to expanding medical education, the government has also approved several allied health programs, including pharmacy, physiotherapy, biomedical sciences, and environmental health. This expansion has been constrained by insufficient numbers of faculty. Through a grant from the Medical Education Partnership Initiative (MEPI), UNZA SOM has been investing in ways to address faculty recruitment, training, and retention. The MEPI-funded strategy involves directly sponsoring a cohort of faculty at UNZA SOM during the five-year grant, as well as establishing more than a dozen new master's programs, with the goal that all sponsored faculty are locally trained and retained. Because the issue of limited basic science faculty plagues medical schools throughout Sub-Saharan Africa, this strategy of using seed funding to build sustainable local capacity to recruit, train, and retain faculty could be a model for the region.

  18. Teaching population health as a basic science at Harvard Medical School.

    PubMed

    Finkelstein, Jonathan A; McMahon, Graham T; Peters, Antoinette; Cadigan, Rebecca; Biddinger, Paul; Simon, Steven R

    2008-04-01

    In 2006-2007, Harvard Medical School implemented a new, required course for first-year medical and dental students entitled Clinical Epidemiology and Population Health. Conceived of as a "basic science" course, its primary goal is to allow students to develop an understanding of caring for individuals and promoting the health of populations as a continuum of strategies, all requiring the engagement of physicians. In the course's first iteration, topical content accessible to first-year students was selected to exemplify physicians' roles in addressing current threats to population health. Methodological areas included domains of clinical epidemiology, decision sciences, population-level prevention and health promotion, physicians' roles in the public health system, and population-level surveillance and intervention strategies. Large-group settings were selectively used to frame the relevance of each topic, and conceptual learning of statistical and epidemiologic methods occurred in conference groups of 24 students. Finally, tutorials of eight students and one or two faculty were used for critical reading of published studies, review of problem sets, and group discussion of population health issues. To help students appreciate the structure and function of the public health system and physicians' role in public health emergencies, the course included a role-playing exercise simulating response to an influenza pandemic. The first iteration of the course was well received, and assessment of students suggested mastery of basic skills. Preclinical courses represent a progressive step in developing a workforce of physicians who embrace their responsibility to improve the health of the population as a whole, as well as the health of the patient in front of them.

  19. The Museum of Science and Industry Basic List of Children's Science Books 1973-1984.

    ERIC Educational Resources Information Center

    Richter, Bernice; Wenzel, Duane

    Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; encyclopedias and reference books; environment and conservation; fiction; general science; life sciences; marine life; mathematics and computer science; medical and health sciences; physics and chemistry; plant…

  20. Why our patients (and we) need basic science research

    PubMed Central

    2013-01-01

    In times of fiscal austerity, the tendency is to seek instant, inexpensive gratification. In the case of biomedical research, this means the shortest path to practical clinical implementation. But fueling the translational pipeline with discovery depends critically on allowing the biomedical research community to follow their science where it takes them. Fiscal constraints carry with them the risk of squelching creativity and forfeiting the power of serendipity to provide the substrate for the translational engine in the future. PMID:23713087

  1. Development and Validation of a Project Package for Junior Secondary School Basic Science

    ERIC Educational Resources Information Center

    Udofia, Nsikak-Abasi

    2014-01-01

    This was a Research and Developmental study designed to develop and validate projects for Junior Secondary School Basic Science instruction and evaluation. The projects were developed using the project blueprint and sent for validation by experts in science education and measurement and evaluation; using a project validation scale. They were to…

  2. Science and Nonscience Students' Ideas about Basic Astronomy Concepts in Preservice Training for Elementary School Teachers

    ERIC Educational Resources Information Center

    Kalkan, Huseyin; Kiroglu, Kasim

    2007-01-01

    A 14-item questionnaire was given to 100 students in preservice training to become primary and secondary education faculty. Results showed that science and non-science majors held a series of misconceptions about several basic topics central to astronomy. The changes in astronomy misconceptions were analyzed by means of a written questionnaire…

  3. Large Scale Computing and Storage Requirements for Basic Energy Sciences Research

    SciTech Connect

    Gerber, Richard; Wasserman, Harvey

    2011-03-31

    The National Energy Research Scientific Computing Center (NERSC) is the leading scientific computing facility supporting research within the Department of Energy's Office of Science. NERSC provides high-performance computing (HPC) resources to approximately 4,000 researchers working on about 400 projects. In addition to hosting large-scale computing facilities, NERSC provides the support and expertise scientists need to effectively and efficiently use HPC systems. In February 2010, NERSC, DOE's Office of Advanced Scientific Computing Research (ASCR) and DOE's Office of Basic Energy Sciences (BES) held a workshop to characterize HPC requirements for BES research through 2013. The workshop was part of NERSC's legacy of anticipating users future needs and deploying the necessary resources to meet these demands. Workshop participants reached a consensus on several key findings, in addition to achieving the workshop's goal of collecting and characterizing computing requirements. The key requirements for scientists conducting research in BES are: (1) Larger allocations of computational resources; (2) Continued support for standard application software packages; (3) Adequate job turnaround time and throughput; and (4) Guidance and support for using future computer architectures. This report expands upon these key points and presents others. Several 'case studies' are included as significant representative samples of the needs of science teams within BES. Research teams scientific goals, computational methods of solution, current and 2013 computing requirements, and special software and support needs are summarized in these case studies. Also included are researchers strategies for computing in the highly parallel, 'multi-core' environment that is expected to dominate HPC architectures over the next few years. NERSC has strategic plans and initiatives already underway that address key workshop findings. This report includes a brief summary of those relevant to issues

  4. Pharmacotherapy of cardiac arrhythmias--basic science for clinicians.

    PubMed

    Shu, Juan; Zhou, Jun; Patel, Chinmay; Yan, Gan-Xin

    2009-11-01

    Cardiac arrhythmias occur in approximately 5.3% of the population and contribute substantially to morbidity and mortality. Pharmacological therapy still remains the major approach in management of patients with nearly every form of cardiac arrhythmia. Effective and safe management of cardiac arrhythmias with antiarrhythmic drugs requires understanding of basic mechanisms for various cardiac arrhythmias, clinical diagnosis of an arrhythmia and identification of underlying cardiac diseases, pharmacokinetics, and antiarrhythmic properties of each individual antiarrhythmic drug. Most cardiac arrhythmias occur via one of the two mechanisms: abnormal impulse formation and reentry or both. Antiarrhythmic drugs primarily work via influencing cardiac automaticity or triggered activity or by their effects on effective refractoriness of cardiac cells. Proarrhythmic effects of antiarrhythmic drugs are also briefly discussed in this review article.

  5. Complex biomedical systems: from basic science to translation.

    PubMed

    Grzywacz, Norberto M

    2012-07-01

    The Department of Biomedical Engineering (BME) of the University of Southern California (BME@USC) has a longstanding tradition of advancing biomedicine through the development and application of novel engineering ideas. More than 80 primary and affiliated faculty members conduct cutting-edge research in a wide variety of areas, such as neuroengineering, biosystems and biosignal analysis, medical devices (including biomicroelectromechanical systems (bioMEMS) and bionanotechnology), biomechanics, bioimaging, and imaging informatics. Currently, the department hosts six internationally recognized research centers: the Biomimetic MicroElectronic Systems Engineering Research Center (funded by the National Science Foundation), the Biomedical Simulations Resource [funded by the National Institutes of Health (NIH)], the Medical Ultrasonic Transducer Center (funded by NIH), the Center for Neural Engineering, the Center for Vision Science and Technology (funded by an NIH Bioengineering Research Partnership Grant), and the Center for Genomic and Phenomic Studies in Autism (funded by NIH). BME@USC ranks in the top tier of all U.S. BME departments in terms of research funding per faculty.

  6. Is basic science disappearing from medicine? The decline of biomedical research in the medical literature.

    PubMed

    Steinberg, Benjamin E; Goldenberg, Neil M; Fairn, Gregory D; Kuebler, Wolfgang M; Slutsky, Arthur S; Lee, Warren L

    2016-02-01

    Explosive growth in our understanding of genomics and molecular biology have fueled calls for the pursuit of personalized medicine, the notion of harnessing biologic variability to provide patient-specific care. This vision will necessitate a deep understanding of the underlying pathophysiology in each patient. Medical journals play a pivotal role in the education of trainees and clinicians, yet we suspected that the amount of basic science in the top medical journals has been in decline. We conducted an automated search strategy in PubMed to identify basic science articles and calculated the proportion of articles dealing with basic science in the highest impact journals for 8 different medical specialties from 1994 to 2013. We observed a steep decline (40-60%) in such articles over time in almost all of the journals examined. This rapid decline in basic science from medical journals is likely to affect practitioners' understanding of and interest in the basic mechanisms of disease and therapy. In this Life Sciences Forum, we discuss why this decline may be occurring and what it means for the future of science and medicine.

  7. Japanese representation in leading general medicine and basic science journals: a comparison of two decades.

    PubMed

    Fukui, Tsuguya; Takahashi, Osamu; Rahman, Mahbubur

    2013-01-01

    During 1991-2000, Japan contribution to the top general medicine journals was very small although the contribution to the top basic science journals was sizeable. However, it has not been examined whether the contribution to the top general medicine and basic science journals has changed during the last decade (2001-2010). The objective of this study was to compare Japan representation in high-impact general medicine and basic science journals between the years 1991-2000 and 2001-2010. We used PubMed database to examine the frequency of articles originated from Japan and published in 7 high-impact general medicine and 6 high-impact basic science journals. Several Boolean operators were used to connect name of the journal, year of publication and corresponding authors' affiliation in Japan. Compared to the 1991-2000 decade, Japan contribution to the top general medicine journals did not increase over the 2001-2010 period (0.66% vs. 0.74%, P = 0.255). However, compared to the same period, its contribution to the top basic science journals increased during 2001-2010 (2.51% vs. 3.60%, P < 0.001). Japan representation in basic science journals showed an upward trend over the 1991-2000 period (P < 0.001) but remained flat during 2001-2010 (P = 0.177). In contrast, the trend of Japan representation in general medicine journals remained flat both during 1991-2000 (P = 0.273) and 2001-2010 (P = 0.073). Overall, Japan contribution to the top general medicine journals has remained small and unchanged over the last two decades. However, top basic science journals had higher Japan representation during 2001-2010 compared to 1991-2000.

  8. Etiology of cicatricial alopecias: a basic science point of view.

    PubMed

    McElwee, Kevin J

    2008-01-01

    This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by a folliculocentric inflammation. However, the specific nature of the inflammatory interference in hair follicle growth is open to question. A popular hypothesis of lymphocyte-mediated scarring alopecia development involves autoimmune targeting of hair follicle-specific self-antigens, although there is no direct evidence in support of such a view. Alternative hypotheses focus on defects in sebaceous gland function, destruction of hair follicle stem cells, and interference in the communication between hair follicle mesenchyme and epithelium. Many questions arise from these hypotheses, and addressing them with a systematic research approach may enable significant advances in understanding cicatricial alopecia etiology.

  9. Using the Planetary Science Institute’s Meteorite Mini-Kits to Address the Nature of Science

    NASA Astrophysics Data System (ADS)

    Lebofsky, Larry A.; Cañizo, Thea L.; Buxner, Sanlyn

    2014-11-01

    Hands-on learning allows students to understand science concepts by directly observing and experiencing the topics they are studying. The Planetary Science Institute (PSI) has created instructional rock kits that have been introduced to elementary and middle school teachers in Tucson, in our professional development workshops. PSI provides teachers with supporting material and training so that they can use the kits as tools for students’ hands-on learning. Use of these kits provides an important experience with natural materials that is essential to instruction in Earth and Space Science. With a stronger knowledge of science content and of how science is actually conducted, the workshops and kits have instilled greater confidence in teachers’ ability to teach science content. The Next Generation Science Standards (NGSS) Performance Expectations includes: “What makes up our solar system?” NGSS emphasizes the Crosscutting Concepts—Patterns Scale, Portion, and Quantity; and Systems and System Models. NGSS also states that the Nature of Science (NOS) should be an “essential part” of science education. NOS topics include understanding that scientific investigations use a variety of methods, that scientific knowledge is based on empirical evidence, that scientific explanations are open to revision in light of new evidence, and an understanding of the nature of scientific models.Addressing a need expressed by teachers for borrowing kits less expensive than our $2000 option, we created a Meteorite Mini-Kit. Each Mini-Kit contains eight rocks: an iron-bearing chondrite, a sliced chondrite (showing iron and chondrules), a tektite, a common Tucson rock, a river-polished rock, pumice, a small iron, and a rounded obsidian rock (false tektite). Also included in the Mini-Kits are magnets and a magnifier. The kits cost $40 to $50, depending on the sizes of the chondrites. A teacher can check out a classroom set of these which contains either 10 or 20 Mini-Kits. Each

  10. NASA DEVELOP Program: Students Extending Earth Science Research to Address Community Needs

    NASA Astrophysics Data System (ADS)

    Richards, A. L.; Ross, A. L.

    2006-12-01

    Eight years ago, several students at NASA Langley Research Center launched the DEVELOP Program. DEVELOP is now at six NASA centers and is a program element of the NASA Applied Sciences Human Capital Development Program that extends the use of Earth observation sources to address Earth science issues in local communities. Students in the program strengthen their leadership and academic skills by analyzing scientific data, experimenting with novel technology, and engaging in cooperative interactions. Graduate, undergraduate and high school students from across the United States collaborate to integrate NASA space-based Earth observation sources and partner agencies' science data, models and decision support tools. Information from these collaborations result in rapid prototype projects addressing local policy and environmental issues. Following a rigorous 10-week term, DEVELOP students present visual products demonstrating the application of NASA scientific information to community leaders at scientific and public policy forums such as the American Geophysical Union (AGU), the American Meteorological Society (AMS), and the Southern Growth Policies Board (SGPB). Submission of written products to peer-reviewed scientific publications and other public databases is also done. Student experiences and interactions working with NASA data, advanced technological programs and community leaders have, and continue to prove, beneficial to student professional development. DEVELOP's human capital development focus affords students real world experience, making them a valuable asset to the scientific and global community and to the continuation of a scientifically aware society. NASA's DEVELOP Program is more than scientific exploration and valuable results; DEVELOP fosters human capital development by bridging the gap between NASA science research and federal, state, local and tribal resource managers.

  11. What's hot, what's new at WTC--basic science.

    PubMed

    Bromberg, J S

    2015-02-01

    The World Transplant Congress of 2014 presented a broad swath of science that touched on many disparate aspects of cell and organ transplantation, molecular and cellular immunology, systems biology, development, technology and translation into humans. A number of themes emerged this year. B cell biology and antibody chemistry were prominent, as they have been for several years. T cells, co-stimulatory blockade and regulatory T cells continue to dominate many aspects of immune research. Many new aspects of monocyte, macrophage, NK cell and NK T cell development, biology and regulation are now being explored. Diverse aspects of organ injury and the acute and chronic responses to injury are being investigated with new techniques, new targets and a resurgent vigor. Novel advances in xenotransplantation and experimental tolerance garnered much attention. Newer investigations in microbiota and nanotechnology promise significant gains in the near future. Lastly the 'omics of DNA, RNA, proteins, metabolites, bacteria and enzyme actions promise new understanding in biological systems and how to control those systems.

  12. Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy

    PubMed Central

    Viero, Cedric; Shibuya, Izumi; Kitamura, Naoki; Verkhratsky, Alexei; Fujihara, Hiroaki; Katoh, Akiko; Ueta, Yoichi; Zingg, Hans H; Chvatal, Alexandr; Sykova, Eva; Dayanithi, Govindan

    2010-01-01

    Is oxytocin the hormone of happiness? Probably not. However, this small nine amino acid peptide is involved in a wide variety of physiological and pathological functions such as sexual activity, penile erection, ejaculation, pregnancy, uterus contraction, milk ejection, maternal behavior, osteoporosis, diabetes, cancer, social bonding, and stress, which makes oxytocin and its receptor potential candidates as targets for drug therapy. In this review, we address the issues of drug design and specificity and focus our discussion on recent findings on oxytocin and its heterotrimeric G protein-coupled receptor OTR. In this regard, we will highlight the following topics: (i) the role of oxytocin in behavior and affectivity, (ii) the relationship between oxytocin and stress with emphasis on the hypothalamo–pituitary–adrenal axis, (iii) the involvement of oxytocin in pain regulation and nociception, (iv) the specific action mechanisms of oxytocin on intracellular Ca2+ in the hypothalamo neurohypophysial system (HNS) cell bodies, (v) newly generated transgenic rats tagged by a visible fluorescent protein to study the physiology of vasopressin and oxytocin, and (vi) the action of the neurohypophysial hormone outside the central nervous system, including the myometrium, heart and peripheral nervous system. As a short nine amino acid peptide, closely related to its partner peptide vasopressin, oxytocin appears to be ideal for the design of agonists and antagonists of its receptor. In addition, not only the hormone itself and its binding to OTR, but also its synthesis, storage and release can be endogenously and exogenously regulated to counteract pathophysiological states. Understanding the fundamental physiopharmacology of the effects of oxytocin is an important and necessary approach for developing a potential pharmacotherapy. PMID:20626426

  13. Earth Institute at Columbia University ADVANCE Program: Addressing Needs for Women in Earth and Environmental Sciences

    NASA Astrophysics Data System (ADS)

    Bell, R. E.; Cane, M.; Mutter, J.; Miller, R.; Pfirman, S.; Laird, J.

    2004-12-01

    The Earth Institute has received a major NSF ADVANCE grant targeted at increasing the participation and advancement of women scientists and engineers in the Academy through institutional transformation. The Earth Institute at Columbia University includes 9 research institutes including Lamont-Doherty Earth Observatory, Center for Environmental Research and Conservation (CERC), Center for International Earth Science Information Network (CIESIN), International Research Institute (IRI) for Climate Prediction, Earth Engineering Center, NASA-Goddard Institute for Space Studies, Center for Risks and Hazards, Center for Globalization and Sustainable Development, and Center for Global Health and Economic Development and six academic departments including Ecology, Evolution and Environmental Biology (E3B, School of Arts and Sciences), Earth and Environmental Engineering (DEEE, School of Engineering and Applied Sciences), Department of Environmental Health (School of Public Health), Department of Earth and Environmental Sciences (DEES, School of Arts and Sciences), Department of International and Public Affairs (School of International and Policy Affairs), and Barnard College Department of Environmental Science. The Earth Institute at Columbia University's ADVANCE program is based both on a study of the status of women at Columbia and research on the progression of women in science elsewhere. The five major targets of the Columbia ADVANCE program are to (1) change the demographics of the faculty through intelligent hiring practices, (2) provide support to women scientists through difficult life transitions including elder care and adoption or birth of a child, (3) enhance mentoring and networking opportunities, (4) implement transparent promotion procedures and policies, and (5) conduct an institutional self study. The Earth Institute ADVANCE program is unique in that it addresses issues that tend to manifest themselves in the earth and environmental fields, such as extended

  14. An international basic science and clinical research summer program for medical students.

    PubMed

    Ramjiawan, Bram; Pierce, Grant N; Anindo, Mohammad Iffat Kabir; Alkukhun, Abedalrazaq; Alshammari, Abdullah; Chamsi, Ahmad Talal; Abousaleh, Mohannad; Alkhani, Anas; Ganguly, Pallab K

    2012-03-01

    An important part of training the next generation of physicians is ensuring that they are exposed to the integral role that research plays in improving medical treatment. However, medical students often do not have sufficient time to be trained to carry out any projects in biomedical and clinical research. Many medical students also fail to understand and grasp translational research as an important concept today. In addition, since medical training is often an international affair whereby a medical student/resident/fellow will likely train in many different countries during his/her early training years, it is important to provide a learning environment whereby a young medical student experiences the unique challenges and value of an international educational experience. This article describes a program that bridges the gap between the basic and clinical research concepts in a unique international educational experience. After completing two semester curricula at Alfaisal University in Riyadh, Kingdom of Saudi Arabia, six medical students undertook a summer program at St. Boniface Hospital Research Centre, in Winnipeg, MB, Canada. The program lasted for 2 mo and addressed advanced training in basic science research topics in medicine such as cell isolation, functional assessment, and molecular techniques of analysis and manipulation as well as sessions on the conduct of clinical research trials, ethics, and intellectual property management. Programs such as these are essential to provide a base from which medical students can decide if research is an attractive career choice for them during their clinical practice in subsequent years. An innovative international summer research course for medical students is necessary to cater to the needs of the medical students in the 21st century.

  15. Neutron Capture Reactions for Stockpile Stewardship and Basic Science

    SciTech Connect

    Parker, W; Agvaanluvsan, U; Becker, J; Wilk, P; Wu, C; Bredeweg, T; Couture, A; Haight, R; Jandel, M; O'Donnell, J; Reifarth, R; Rundberg, R; Ullmann, J; Vieira, D; Wouters, J; Sheets, S; Mitchell, G; Becvar, F; Krticka, M

    2007-08-04

    The capture process is a nuclear reaction in which a target atom captures an incident projectile, e.g. a neutron. The excited-state compound nucleus de-excites by emitting photons. This process creates an atom that has one more neutron than the target atom, so it is a different isotope of the same element. With low energy (slow) neutron projectiles, capture is the dominant reaction, other than elastic scattering. However, with very heavy nuclei, fission competes with capture as a method of de-excitation of the compound nucleus. With higher energy (faster) incident neutrons, additional reactions are also possible, such as emission of protons or emission of multiple neutrons. The probability of a particular reaction occurring (such as capture) is referred to as the cross section for that reaction. Cross sections are very dependent on the incoming neutron's energy. Capture reactions can be studied either using monoenergetic neutron sources or 'white' neutron sources. A 'white' neutron source has a wide range of neutron energies in one neutron beam. The advantage to the white neutron source is that it allows the study of cross sections as they depend on neutron energies. The Los Alamos Neutron Science Center, located at Los Alamos National Laboratory, provides an intense white neutron source. Neutrons there are created by a high-energy proton beam from a linear accelerator striking a heavy metal (tungsten) target. The neutrons range in energy from subthermal up to very fast - over 100 MeV in energy. Low-energy neutron reaction cross sections fluctuate dramatically from one target to another, and they are very difficult to predict by theoretical modeling. The cross sections for particular capture reactions are important for defense sciences, advanced reactor concepts, transmutation of radioactive wastes and nuclear astrophysics. We now have a strong collaboration between Lawrence Livermore National Laboratory, Los Alamos National Laboratory, North Carolina State

  16. The challenge for basic science education in problem-based medical curricula.

    PubMed

    Sweeney, G

    1999-02-01

    There has been intense debate about medical curriculum reform since the early 1950s. The last 25 years have seen a steady shift ward problem-based learning curriculum design in schools of medicine and allied health sciences. This trend has been less challenging for clinical departments than for departments of basic science, where it has often evoked anxiety, antipathy, lack of cooperation, and general mistrust. This appears paradoxical, as problem-based learning (PBL) is promoted as an improved method of integrating scientific concepts, and the advances that drive much of modern medical practice are advances in the basic sciences. While proponents of PBL argue that the approach promotes better integration and use of scientific concepts, the evidence, such as it is, is against this. As well, other evidence suggests that clinicians do not use basic science concepts extensively in their practice. This then questions the utility of scientific knowledge in a medical curriculum. This article examines this notion of utility (the quality or state of being useful), to establish some ground rules for what does, and does not, possess utility, and to present strategies to develop specific objectives from general statements concerning utility. Understanding of biologic and pathologic processes becomes of central importance and arguably possesses utility. If it is both required and evaluated, such understanding necessitates mastery of basic science concepts. Previously, the presentation of the basic sciences in medical curricula has emphasized the acquisition of knowledge rather than its use. Such learning has been perceived to lack utility; strategies to enhance the value of studying basic science concepts are suggested. If the importance of objectives in the basic medical sciences is accepted, these objectives should be achieved early in training, maintained at exit from medical school, and revisited in continuing medical education. The process of change in medical education

  17. Earth-Science Research for Addressing the Water-Energy Nexus

    NASA Astrophysics Data System (ADS)

    Healy, R. W.; Alley, W. M.; Engle, M.; McMahon, P. B.; Bales, J. D.

    2013-12-01

    In the coming decades, the United States will face two significant and sometimes competing challenges: preserving sustainable supplies of fresh water for humans and ecosystems, and ensuring available sources of energy. This presentation provides an overview of the earth-science data collection and research needed to address these challenges. Uncertainty limits our understanding of many aspects of the water-energy nexus. These aspects include availability of water, water requirements for energy development, energy requirements for treating and delivering fresh water, effects of emerging energy development technologies on water quality and quantity, and effects of future climates and land use on water and energy needs. Uncertainties can be reduced with an integrated approach that includes assessments of water availability and energy resources; monitoring of surface water and groundwater quantity and quality, water use, and energy use; research on impacts of energy waste streams, hydraulic fracturing, and other fuel-extraction processes on water quality; and research on the viability and environmental footprint of new technologies such as carbon capture and sequestration and conversion of cellulosic material to ethanol. Planning for water and energy development requires consideration of factors such as economics, population trends, human health, and societal values; however, sound resource management must be grounded on a clear understanding of the earth-science aspects of the water-energy nexus. Information gained from an earth-science data-collection and research program can improve our understanding of water and energy issues and lay the ground work for informed resource management.

  18. Discrimination, developmental science, and the law: addressing dramatic shifts in civil rights jurisprudence.

    PubMed

    Levesque, Roger J R

    2014-01-01

    The civil rights movement fostered dramatic shifts in legal responses to discrimination based on race, gender, and a host of other group characteristics. The legal system now evinces yet another dramatic shift, as it moves from considering difference to focusing on neutrality, from efforts that seek to counter subjugation to those that adopt a "color-blind" approach. The shifting approach already has reached laws regulating responses to the group that spurred massive civil rights reform: minority youth. The shift requires a different body of empirical evidence to address it and a new look at equality jurisprudence. This article notes the need to turn to the current understanding of prejudice and discrimination for guidance, and uses, as illustration, developmental science to shed light on the development, manifestation, and alleviation of invidious discrimination. Using that understanding, the analysis details how the legal system can benefit from that research and better address discrimination in light of dramatic changes in law. The article articulates the need to address discrimination by recognizing and enlisting the law's inculcative powers through multiple sites of inculcation, ranging from families, schools, health and justice systems to religious and community groups. The discussion concludes with brief suggestions for reform benefiting from understandings of prejudice and its expression.

  19. Lost in Translation—Basic Science in the Era of Translational Research ▿

    PubMed Central

    Fang, Ferric C.; Casadevall, Arturo

    2010-01-01

    The concept of translational research, which aims to facilitate the application of basic scientific discoveries in clinical and community settings, is currently in vogue. While there are powerful forces driving this trend, support for translational research must be accompanied by a robust investment in basic science, which provides the essential raw material for translation and continues to represent humanity's best hope to meet a wide range of public health challenges. PMID:20038540

  20. The Right to Basic Education for All: Addressing the Educational Needs and Barriers of Immigrant Learners in South Africa

    ERIC Educational Resources Information Center

    Marishane, Nylon

    2013-01-01

    The South African Constitution guarantees the right to basic education for all learners, including children of immigrants from across the country's borders. In view of this constitutional imperative, the Department of Basic Education is mandated to provide quality education to all learners, irrespective of their socio-economic and other…

  1. Bench to bedside: integrating advances in basic science into daily clinical practice.

    PubMed

    McGoldrick, Rory B; Hui, Kenneth; Chang, James

    2014-08-01

    This article focuses on the initial steps of commercial development of a patentable scientific discovery from an academic center through to marketing a clinical product. The basics of partnering with a technology transfer office (TTO) and the complex process of patenting are addressed, followed by a discussion on marketing and licensing the patent to a company in addition to starting a company. Finally, the authors address the basic principles of obtaining clearance from the Food and Drugs Administration, production in a good manufacturing practice (GMP) facility, and bringing the product to clinical trial.

  2. Clinical and basic science teachers' opinions about the required depth of biomedical knowledge for medical students.

    PubMed

    Koens, Franciska; Custers, Eugène J F M; ten Cate, Olle T J

    2006-05-01

    The aim of the present study was to investigate whether basic scientists and physicians agree on the required depth of biomedical knowledge of medical students at graduation. A selection of basic science and clinical teachers rated the relevance of biomedical topics for students at graduation, illustrated by 80 example items. The items were derived from ten organ systems and designed at four levels: clinical, organ, cellular and molecular. Respondents were asked to identify for each item to what extent recently graduated medical students should have knowledge about it. In addition, they were asked to indicate whether the content of the item should be included in the medical curriculum. Analysis showed that basic scientists and physicians do not diverge at the clinical level. At the organ, cellular and molecular levels however, basic scientists judge that medical students should have more active knowledge. As expected, basic scientists also indicate that more deep level content should be included. Explanations for this phenomenon will be discussed.

  3. Data and Communications in Basic Energy Sciences: Creating a Pathway for Scientific Discovery

    SciTech Connect

    Nugent, Peter E.; Simonson, J. Michael

    2011-10-24

    This report is based on the Department of Energy (DOE) Workshop on “Data and Communications in Basic Energy Sciences: Creating a Pathway for Scientific Discovery” that was held at the Bethesda Marriott in Maryland on October 24-25, 2011. The workshop brought together leading researchers from the Basic Energy Sciences (BES) facilities and Advanced Scientific Computing Research (ASCR). The workshop was co-sponsored by these two Offices to identify opportunities and needs for data analysis, ownership, storage, mining, provenance and data transfer at light sources, neutron sources, microscopy centers and other facilities. Their charge was to identify current and anticipated issues in the acquisition, analysis, communication and storage of experimental data that could impact the progress of scientific discovery, ascertain what knowledge, methods and tools are needed to mitigate present and projected shortcomings and to create the foundation for information exchanges and collaboration between ASCR and BES supported researchers and facilities. The workshop was organized in the context of the impending data tsunami that will be produced by DOE’s BES facilities. Current facilities, like SLAC National Accelerator Laboratory’s Linac Coherent Light Source, can produce up to 18 terabytes (TB) per day, while upgraded detectors at Lawrence Berkeley National Laboratory’s Advanced Light Source will generate ~10TB per hour. The expectation is that these rates will increase by over an order of magnitude in the coming decade. The urgency to develop new strategies and methods in order to stay ahead of this deluge and extract the most science from these facilities was recognized by all. The four focus areas addressed in this workshop were: Workflow Management - Experiment to Science: Identifying and managing the data path from experiment to publication. Theory and Algorithms: Recognizing the need for new tools for computation at scale, supporting large data sets and realistic

  4. The South Carolina Amazing Coast Program: Using Ocean Sciences to Address Next Generation Science Standards in Grades 3-5

    NASA Astrophysics Data System (ADS)

    Bell, E. V.; Thomas, C.; Weiss, B.; Bliss, A.; Spence, L.

    2013-12-01

    The Next Generation Science Standards (NGSS) are more inclusive of ocean sciences than the National Science Standards and respective state science standards. In response, the Center for Ocean Sciences Education Excellence-SouthEast (COSEE SE) is piloting the South Carolina's Amazing Coast (SCAC) program: a three-year initiative that incorporates ocean science concepts in grades 3-5 with the goals of addressing NGSS, STEM (science-technology-engineering-math) disciplines, and inquiry skills. The SCAC program targeted two Charleston County, South Carolina elementary schools that were demographically similar: Title 1 status (75% free or reduced lunch), > 90% African American student population, grade level size <55, and proximity to tidal salt marsh or barrier islands (< 2 miles). Fourteen teachers and approximately 240 students participated in the SCAC program between 2010 and 2013. The SCAC framework uses a scaffolding and multi-pronged approach for teacher professional development and student engagement. The scaffolding approach to curriculum implementation focuses on one grade level per year (Year 1 = 3rd; Year 2 = 4th, and Year 3 = 5th), thus building student and teacher literacy in ocean sciences. The coach-mentor model of teacher professional development was also used for the implementation of the program which differs from the traditional 'train the trainer' method in allowing for more frequent and consistent interaction by COSEE SE staff with the students and teachers during the school year. The coach mentor model enabled the creation of a community of practice where teachers served as both learners and practitioners of student learning. Methods for student engagement aligned with the NGSS and included hands-on classroom activities, use of 'hook' species such as loggerhead sea turtles (Caretta caretta), diamondback terrapins (Malaclemys terrapin) and smooth cord grass (Spartina alterniflora), field experiences to explore local ecosystems, interactions with

  5. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    ERIC Educational Resources Information Center

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2013-01-01

    Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…

  6. Improving College Faculty Instruction in the Basic and Allied Health Sciences.

    ERIC Educational Resources Information Center

    Washton, Nathan S.

    A project to improve college instruction in the basic and allied health sciences at New York Chiropractic College and the New York Institute of Technology is described. Attention was directed to: the kinds of resources colleges and professional schools provide to improve instruction; motivation of faculty to explore innovative or strategic…

  7. Pair Comparison Study of the Relevance of Nine Basic Science Courses

    ERIC Educational Resources Information Center

    Spilman, Edra L.; Spilman, Helen W.

    1975-01-01

    Reports a survey study in which basic science courses were rated according to relevance. Notes approaches for making the anatomy disciplines more relevant because results showed them of lowest relevancy compared with physiology, pathology, and pharmacology which were rated of highest relevance and with biochemistry and microbiology which fell…

  8. Evaluation of a Basic Science, Peer Tutorial Program for First- and Second-Year Medical Students.

    ERIC Educational Resources Information Center

    Trevino, Fernando M.; Eiland, D. C., Jr.

    1980-01-01

    A peer tutorial program in the basic sciences implemented at the University of Texas Medical Branch at Galveston is evaluated. The grades of students receiving peer tutorials were analyzed and questionnaires were mailed to each participant soliciting their evaluation of services received. Future cost-benefit evaluations are planned. (Author/MLW)

  9. Effects of Concept Mapping Instruction Approach on Students' Achievement in Basic Science

    ERIC Educational Resources Information Center

    Ogonnaya, Ukpai Patricia; Okafor, Gabriel; Abonyi, Okechukwu S.; Ugama, J. O.

    2016-01-01

    The study investigated the effects of concept mapping on students' achievement in basic science. The study was carried out in Ebonyi State of Nigeria. The study employed a quasi-experimental design. Specifically the pretest posttest non-equivalent control group research design was used. The sample was 122 students selected from two secondary…

  10. Using "Basic Principles" to Understand Complex Science: Nicotine Smoke Chemistry and Literature Analogies

    ERIC Educational Resources Information Center

    Seeman, Jeffrey I.

    2005-01-01

    The chemical and physical properties of nicotine and its carboxylic acid salts found in tobacco provided as an interesting example to understand basic principles of complex science. The result showed that the experimental data used were inconsistent to the conclusion made, and the transfer of nicotine smoke from tobacco to smoke cannot be…

  11. Peer-Assisted Learning: Filling the Gaps in Basic Science Education for Preclinical Medical Students

    ERIC Educational Resources Information Center

    Sammaraiee, Yezen; Mistry, Ravi D.; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth

    2016-01-01

    In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United…

  12. Integrating Basic Science and Clinical Teaching for Third-Year Medical Students.

    ERIC Educational Resources Information Center

    Croen, Lila G.; And Others

    1986-01-01

    A 2-month program for third-year students at Yeshiva's Albert Einstein College of Medicine that provides a model for integrating basic sciences and clinical training is described. It demonstrates the importance of lifelong learning in a field that constantly changes. (Author/MLW)

  13. Using a Database to Analyze Core Basic Science Content in a Problem-Based Curriculum.

    ERIC Educational Resources Information Center

    Rosen, Robert L.; And Others

    1992-01-01

    A study used computer analysis to examine distribution of basic science content in the 53 cases in the problem-based medical curriculum of Rush Medical College (Illinois) and compared it to application of that content by students and faculty. The method of analysis is recommended for reviewing curricula for omissions and redundancy. (Author/MSE)

  14. Effect of Self Regulated Learning Approach on Junior Secondary School Students' Achievement in Basic Science

    ERIC Educational Resources Information Center

    Nwafor, Chika E.; Obodo, Abigail Chikaodinaka; Okafor, Gabriel

    2015-01-01

    This study explored the effect of self-regulated learning approach on junior secondary school students' achievement in basic science. Quasi-experimental design was used for the study.Two co-educational schools were drawn for the study through simple random sampling technique. One school was assigned to the treatment group while the other was…

  15. An Analysis of Taiwanese Eighth Graders' Science Achievement, Scientific Epistemological Beliefs and Cognitive Structure Outcomes After Learning Basic Atomic Theory.

    ERIC Educational Resources Information Center

    Tsai, Chin-Chung

    1998-01-01

    Explores the interrelationships between students' general science achievement, scientific epistemological beliefs, and cognitive structure outcomes derived from instruction of basic atomic theory. Contains 19 references. (DDR)

  16. A review of strategies to address the shortage of science and mathematics educators in grades 10-12

    NASA Astrophysics Data System (ADS)

    Magano, Florence Lesedi

    For an education system to function effectively it is important that its planning functions are executed effectively and efficiently. Among others this implies that the system must know what the teacher supply and demand is and how it will change in time. If the teacher supply and demand is known it could result in sound intervention strategies being developed and implemented. Education planners will be able to plan for the number of bursaries to be awarded and in which subject fields; it will be known how many foreign teachers to employ and for which subjects. This is the basic rationale that underpins this study. This study explored the problem of teacher demand and supply in the Further Education and Training (FET) phase (Grades 10 to 12) in South Africa and offers a critical analysis of strategies adopted by Provincial Education Departments in an endeavour to diminish the demand for teachers, specifically for Mathematics and Science, in rural and poor schools. Initially the study involved a secondary data analysis to extrapolate the demand and supply of teachers in Mathematics and Science over the next ten years. The first key finding of the study was that the data needed for such an analysis does not exist in any reliable form that would facilitate the development of such a projection. What the study had to rely on was anecdotal evidence that suggests that a shortage of Mathematics and Science teachers does exist and that posts are often filled by unqualified and under-qualified staff. In the second phase of the research in which the study explored the effectiveness of strategies developed to address the shortage of Mathematics and Science teachers, a qualitative research approach was adopted within a descriptive interpretive design. The views and opinions of human resource managers responsible for post provisioning in schools were explored through in-depth interviews to understand the types of strategy adopted by the provinces, their potential to alleviate

  17. Basic research championed

    NASA Astrophysics Data System (ADS)

    Friebele, Elaine

    In April, the Office of National Science and Technology Policy released its biennial report to Congress. Science and Technology: Shaping the Twenty-First Century addresses the President's policy for maintaining U.S. leadership in science and technology, significant developments, and important national issues in science, and opportunities to use science and technology in federal programs and national goals. The administration strongly supports basic research as a sound investment and an inspiration to society. As corporate laboratories increasingly favor applied R&D projects, the federal government is becoming the dominant sponsor of long-term, basic research.

  18. United Nations/European Space Agency Workshops on Basic Space Science

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.

    1995-02-01

    In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica and Colombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.

  19. United Nations/European Space Agency Workshops on Basic Space Science

    NASA Technical Reports Server (NTRS)

    Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.

    1995-01-01

    In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica andColombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.

  20. Interconnections of basic science research and product development in medical device design.

    PubMed

    Privitera, Mary Beth; Design, M; Johnson, Jeffrey

    2009-01-01

    The relationship between basic science research and product design/development are intertwined. This paper explores the definition of basic science and design as it relates to medical device development. It is intended to serve as a reference for both researchers and device developers to assist in trans-disciplinary collaborative efforts in improving patient care as each are of equal importance. The definition of a medical device is broad and varied. This paper is aimed towards those devices which interact with tissue and are rooted in the tenets of science. Both the scientific method and the design process are compared with similarities and opposites identified. The paper concludes identifying fundamental principles of medical device development and highlights the importance of both entities.

  1. Changing educational needs of psychologists: do we need more medical knowledge, basic science and more psychological science?

    PubMed

    Belar, Cynthia D

    2008-03-01

    Psychologists of the 21st century must be highly skilled and versatile to function effectively in academic health centers (AHCs). Thus, the current paper focuses on the training psychologists receive to prepare them for their diverse roles in AHCs. The paper is framed around the question: Do we need more medical knowledge, basic science and more psychological science? posed to the author by the conference organizers of the 3rd National Association of Psychologists in Academic Health Centers (APAHC) Conference and is based on the perspective of the author.

  2. Science and scientific literacy vs science and scientific awareness through basic physics lectures: A study of wish and reality

    NASA Astrophysics Data System (ADS)

    Rusli, Aloysius

    2012-06-01

    Scientific literacy was already discussed in the 1950s, as a prerequisite for the general citizen in a world increasingly served and infused by science and technology: the so-called knowledge or learning society. This kind of literacy has been described in detail by Victor Showalter in 1975, expanded by others, and later defined succinctly by the OECD in 2003. As a complement, science literacy is described also by the National Science Digital Library (NSDL) as a content knowledge needed in setting up practical models for handling daily matters with science and engineering. These important and worthy aims were studied, and compared with reality and existing conditions. One hypothesis put forward and argued for is, that it is more realistic, considering existing trends, to aim for scientific and science awareness for the general student, while scientific and science literacy remain important and worthy aims for the common good of the global community, and important to be strived for by teachers, lecturers and intellectuals. The Basic Physics lectures can also lend themselves usefully for the more realistic aim, due to the science-based nature of the present knowledge society.

  3. Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicine.

    PubMed

    Nesse, Randolph M; Bergstrom, Carl T; Ellison, Peter T; Flier, Jeffrey S; Gluckman, Peter; Govindaraju, Diddahally R; Niethammer, Dietrich; Omenn, Gilbert S; Perlman, Robert L; Schwartz, Mark D; Thomas, Mark G; Stearns, Stephen C; Valle, David

    2010-01-26

    New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease.

  4. Operant conditioning of spinal reflexes: from basic science to clinical therapy

    PubMed Central

    Thompson, Aiko K.; Wolpaw, Jonathan R.

    2014-01-01

    New appreciation of the adaptive capabilities of the nervous system, recent recognition that most spinal cord injuries are incomplete, and progress in enabling regeneration are generating growing interest in novel rehabilitation therapies. Here we review the 35-year evolution of one promising new approach, operant conditioning of spinal reflexes. This work began in the late 1970’s as basic science; its purpose was to develop and exploit a uniquely accessible model for studying the acquisition and maintenance of a simple behavior in the mammalian central nervous system (CNS). The model was developed first in monkeys and then in rats, mice, and humans. Studies with it showed that the ostensibly simple behavior (i.e., a larger or smaller reflex) rests on a complex hierarchy of brain and spinal cord plasticity; and current investigations are delineating this plasticity and its interactions with the plasticity that supports other behaviors. In the last decade, the possible therapeutic uses of reflex conditioning have come under study, first in rats and then in humans. The initial results are very exciting, and they are spurring further studies. At the same time, the original basic science purpose and the new clinical purpose are enabling and illuminating each other in unexpected ways. The long course and current state of this work illustrate the practical importance of basic research and the valuable synergy that can develop between basic science questions and clinical needs. PMID:24672441

  5. FWP executive summaries, Basic Energy Sciences Materials Sciences Programs (SNL/NM)

    SciTech Connect

    Samara, G.A.

    1997-05-01

    The BES Materials Sciences Program has the central theme of Scientifically Tailored Materials. The major objective of this program is to combine Sandia`s expertise and capabilities in the areas of solid state sciences, advanced atomic-level diagnostics and materials synthesis and processing science to produce new classes of tailored materials as well as to enhance the properties of existing materials for US energy applications and for critical defense needs. Current core research in this program includes the physics and chemistry of ceramics synthesis and processing, the use of energetic particles for the synthesis and study of materials, tailored surfaces and interfaces for materials applications, chemical vapor deposition sciences, artificially-structured semiconductor materials science, advanced growth techniques for improved semiconductor structures, transport in unconventional solids, atomic-level science of interfacial adhesion, high-temperature superconductors, and the synthesis and processing of nano-size clusters for energy applications. In addition, the program includes the following three smaller efforts initiated in the past two years: (1) Wetting and Flow of Liquid Metals and Amorphous Ceramics at Solid Interfaces, (2) Field-Structured Anisotropic Composites, and (3) Composition-Modulated Semiconductor Structures for Photovoltaic and Optical Technologies. The latter is a joint effort with the National Renewable Energy Laboratory. Separate summaries are given of individual research areas.

  6. What Type of Faculty and Training Are Required for a Successful Basic Sciences Program?

    ERIC Educational Resources Information Center

    Adams, Anthony

    1992-01-01

    Science education for optometry must go beyond therapeutic patient management to more preparation for biologically based care. Optometry faculty should be involved in research driven by specific patient problems and should prepare professionals to address patient quality-of-life and daily living needs. Interdisciplinary collaboration is needed.…

  7. The Presidential Address 2013: Promoting Enthusiasm, Imparting Knowledge! Science for the General Population and Science for Future Researchers Must All Start in the School Curriculum

    ERIC Educational Resources Information Center

    Rees, Martin

    2013-01-01

    This article provides a transcript of the Presidential Address delivered by Martin Rees, Lord Rees of Ludlow, to the Association for Science Education (ASE) Annual Conference at the University of Reading, January 2013. The address is divided into five sections under the following headings: (1) Three Reasons Why the ASE's Mission Is So Important;…

  8. Evaluation of Some Approved Basic Science and Technology Textbooks in Use in Junior Secondary Schools in Nigeria

    ERIC Educational Resources Information Center

    Nwafor, C. E.; Umoke, C. C.

    2016-01-01

    This study was designed to evaluate the content adequacy and readability of approved basic science and technology textbooks in use in junior secondary schools in Nigeria. Eight research questions guided the study. The sample of the study consisted of six (6) approved basic science and technology textbooks, 30 Junior Secondary Schools randomly…

  9. Extending the Purposes of Science Education: Addressing Violence within Socio-Economic Disadvantaged Communities

    ERIC Educational Resources Information Center

    Castano, Carolina

    2012-01-01

    Current discourses about science education show a wide concern towards humanisation and a more socio-cultural perspective of school science. They suggest that science education can serve diverse purposes and be responsive to social and environmental situations we currently face. However, these discourses and social approaches to science education…

  10. Defense, basic, and industrial research at the Los Alamos Neutron Science Center: Proceedings

    SciTech Connect

    Longshore, A.; Salgado, K.

    1995-10-01

    The Workshop on Defense, Basic, and Industrial Research at the Los Alamos Neutron Science Center gathered scientists from Department of Energy national laboratories, other federal institutions, universities, and industry to discuss the use of neutrons in science-based stockpile stewardship, The workshop began with presentations by government officials, senior representatives from the three weapons laboratories, and scientific opinion leaders. Workshop participants then met in breakout sessions on the following topics: materials science and engineering; polymers, complex fluids, and biomaterials; fundamental neutron physics; applied nuclear physics; condensed matter physics and chemistry; and nuclear weapons research. They concluded that neutrons can play an essential role in science-based stockpile stewardship and that there is overlap and synergy between defense and other uses of neutrons in basic, applied, and industrial research from which defense and civilian research can benefit. This proceedings is a collection of talks and papers from the plenary, technical, and breakout session presentations. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  11. PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies.

    PubMed

    Zhou, Yiqin; Wang, James H-C

    2016-01-01

    Platelet-Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is controversial. This paper focuses on reviewing the basic science studies on PRP performed under well-controlled conditions. Both in vitro and in vivo studies describe PRP's anabolic and anti-inflammatory effects on tendons. While some clinical trials support these findings, others refute them. In this review, we discuss the effectiveness of PRP to treat tendon injuries with evidence presented in basic science studies and the potential reasons for the controversial results in clinical trials. Finally, we comment on the approaches that may be required to improve the efficacy of PRP treatment for tendinopathy.

  12. PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies

    PubMed Central

    2016-01-01

    Platelet-Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is controversial. This paper focuses on reviewing the basic science studies on PRP performed under well-controlled conditions. Both in vitro and in vivo studies describe PRP's anabolic and anti-inflammatory effects on tendons. While some clinical trials support these findings, others refute them. In this review, we discuss the effectiveness of PRP to treat tendon injuries with evidence presented in basic science studies and the potential reasons for the controversial results in clinical trials. Finally, we comment on the approaches that may be required to improve the efficacy of PRP treatment for tendinopathy. PMID:27610386

  13. Research programs for Division of Chemical Sciences, Office of Basic Energy Sciences, Department of Energy

    SciTech Connect

    Not Available

    1988-01-01

    A chemical sciences review meeting was held in which research programs in chemistry were discussed. Major topics included: chemistry of actinides and fission products, interactions of solvents, solutes and surfaces in supercritical extraction, chemical and physical principles in multiphase separations, and chemical kinetics of enzyme catalyzed reactions. Individual projects are processed separately for the data bases. (CBS)

  14. Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies.

    PubMed

    Brookes, S J; Dinning, P G; Gladman, M A

    2009-12-01

    Colorectal physiology is complex and involves programmed, coordinated interaction between muscular and neuronal elements. Whilst a detailed understanding remains elusive, novel information has emerged from recent basic science and human clinical studies concerning normal sensorimotor mechanisms and the organization and function of the key elements involved in the control of motility. This chapter summarizes these observations to provide a contemporary review of the neuroanatomy and physiology of colorectal function and defaecation.

  15. Neutron transfer reactions: Surrogates for neutron capture for basic and applied nuclear science

    SciTech Connect

    Cizewski, J. A.; Jones, K. L.; Kozub, R. L.; Pain, Steven D; Peters, W. A.; Adekola, Aderemi S; Allen, J.; Bardayan, Daniel W; Becker, J.; Blackmon, Jeff C; Chae, K. Y.; Chipps, K.; Erikson, Luke; Gaddis, A. L.; Harlin, Christopher W; Hatarik, Robert; Howard, Joshua A; Jandel, M.; Johnson, Micah; Kapler, R.; Krolas, W.; Liang, J Felix; Livesay, Jake; Ma, Zhanwen; Matei, Catalin; Matthews, C.; Moazen, Brian; Nesaraja, Caroline D; O'Malley, Patrick; Patterson, N. P.; Paulauskas, Stanley; Pelham, T.; Pittman, S. T.; Radford, David C; Rogers, J.; Schmitt, Kyle; Shapira, Dan; ShrinerJr., J. F.; Sissom, D. J.; Smith, Michael Scott; Swan, T. P.; Thomas, J. S.; Vieira, D. J.; Wilhelmy, J. B.; Wilson, Gemma L

    2009-04-01

    Neutron capture reactions on unstable nuclei are important for both basic and applied nuclear science. A program has been developed at the Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory to study single-neutron transfer (d,p) reactions with rare isotope beams to provide information on neutron-induced reactions on unstable nuclei. Results from (d,p) studies on {sup 130,132}Sn, {sup 134}Te and {sup 75}As are discussed.

  16. Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials.

    PubMed

    An, G

    2001-10-01

    The management of Systemic Inflammatory Response Syndrome (SIRS)/Multiple Organ Failure (MOF) remains the greatest challenge in the field of critical care. There has been uniform difficulty in translating the results of basic science research into effective therapeutic regimes. We propose that this is due in part to a failure to account for the complex, nonlinear nature of the inflammatory process of which SIRS/MOF represents a disordered state. Attempts to manipulate this process without an understanding of the dynamics of the system may potentially produce unintended consequences. Agent-Based Computer Simulation (ABCS) provides a means to synthesize the information acquired from the linear analysis of basic science into a model that preserves the complexity of the inflammatory system. We have constructed an abstracted version of the inflammatory process using an ABCS that is based at the cellular level. Despite its abstraction, the simulation produces non-linear behavior and reproduces the dynamic structure of the inflammatory response. Furthermore, adjustment of the simulation to model one of the unsuccessful initial anti-inflammatory trials of the 1990's demonstrates the adverse outcome that was observed in those clinical trials. It must be emphasized that the current model is extremely abstract and simplified. However, it is hoped that future ABCSs of sufficient sophistication eventually may provide an important bridging tool to translate basic science discoveries into clinical applications. Creating these simulations will require a large collaborative effort, and it is hoped that this paper will stimulate interest in this form of analysis.

  17. A report of the Basic Energy Sciences Advisory Committee: 1992 review of the Basic Energy Sciences Program of the Department of Energy

    SciTech Connect

    Not Available

    1993-09-01

    The general quality of BES research at each of the 4 laboratories is high. Diversity of management at the different laboratories is beneficial as long as the primary BES mission and goals are clearly identified and effectively pursued. External sources of personnel should be encouraged. DOE has been designing a new high flux research reactor, the Advanced Neutron Source, to replace DOE`s two aging research reactors; BESAC conducted a panel evaluation of neutron sources for the future. The two new light sources, Advanced Light Source and Advanced Photon source will come on line well before all of their beamline instrumentation can be funded, developed, and installed. Appointment of a permanent director and deputy for OBES would enhance OBES effectiveness in budget planning and intra-DOE program coordination. Some DOE and DP laboratories have substantial infrastructure which match well industry development-applications needs; interlaboratory partnerships in this area are encouraged. Funding for basic science research programs should be maintained at FY1993 levels, adjusted for inflation; OBES plans should be updated and monitored to maintain the balance between basic research and facilities construction and operation. The recommendations are discussed in detail in this document.

  18. Materials Sciences Programs. Fiscal Year 1980, Office of Basic Energy Sciences

    SciTech Connect

    Not Available

    1980-09-01

    This report provides a convenient compilation index of the DOE Materials Sciences Division programs. This compilation is intended for use by administrators, managers, and scientists to help coordinate research and as an aid in selecting new programs and is divided into Sections A and B, listing all the projects, Section C, a summary of funding levels, and Section D, an index (the investigator index is in two parts - laboratory and contract research).

  19. Addressing Diversity in Health Science Students by Enhancing Flexibility through e-Learning

    ERIC Educational Resources Information Center

    Penman, Joy; Thalluri, Jyothi

    2014-01-01

    The technological advancements for teaching and learning sciences for health science students are embedded in the Thalluri-Penman Good Practice Model, which aims to improve the learning experiences of science students and increase student retention and success rates. The model also links students from urban and rural areas, studying both on-and…

  20. Science Teachers' Use of Mass Media to Address Socio-Scientific and Sustainability Issues

    ERIC Educational Resources Information Center

    Klosterman, Michelle L.; Sadler, Troy D.; Brown, Julie

    2012-01-01

    The currency, relevancy and changing nature of science makes it a natural topic of focus for mass media outlets. Science teachers and students can capitalize on this wealth of scientific information to explore socio-scientific and sustainability issues; however, without a lens on how those media are created and how representations of science are…

  1. Ozone and Interdisciplinary Science Teaching--Learning to Address the Things That Count Most.

    ERIC Educational Resources Information Center

    Hobson, Art

    1993-01-01

    Presents the ozone depletion story as an excellent case study for the integration of science-related social issues into the college science curriculum. Describes the history of ozone depletion and efforts to remedy the problem. Provides a lecture outline on ozone depletion. Discusses integrating other science-related interdisciplinary topics in…

  2. Extending the purposes of science education: addressing violence within socio-economic disadvantaged communities

    NASA Astrophysics Data System (ADS)

    Castano, Carolina

    2012-09-01

    Current discourses about science education show a wide concern towards humanisation and a more socio-cultural perspective of school science. They suggest that science education can serve diverse purposes and be responsive to social and environmental situations we currently face. However, these discourses and social approaches to science education tend to focus on global issues. They do not respond to the immediate needs and local context of some communities. I discuss in this paper why the purposes of science education need to be extended to respond to the local issue of violence. For this, I present a case study with a group of 38 students from a poor population in Bogotá, Colombia, located in one of the suburbs with highest levels of crime in the city. I examine the ways that science education contributes to and embodies its own forms of violence and explore how a new approach to science education could contribute to break the cycle of violence.

  3. Moving beyond "Those Kids": Addressing Teacher Beliefs Regarding the Role of Culture within Effective Science Pedagogy for Diverse Learners

    ERIC Educational Resources Information Center

    Johnson, Carla C.; Bolshakova, Virginia L. J.

    2015-01-01

    This study focused on intensive work within a large, urban, low-performing middle school in the southwest to address and transform teacher beliefs regarding the role of culture within their science pedagogy. Given the recent, rapid growth of numbers of students from Hispanic/Latino(a) backgrounds in the United States, it is critical that a…

  4. Basic science and its relationship to environmental restoration: Preparing for the 21. century. Summary report

    SciTech Connect

    1995-12-31

    The Department of Energy (DOE) funded the two day meeting in order to focus on ways to organize and mobilize the scientific community to effectively address the maze of global environmental problems. Using the Office of Energy Research (ER) as a Test Case, the participants were asked to address such questions as: What are the problems ER can effectively address? Is there a hierarchy of issues involved in attacking those problems? Are there new multi-disciplinary constructs that should be encouraged in the university environment, much like the applied science departments that developed at many institutions in the 1970`s and 1980`s; and/or in the national laboratories? What does it take to get the best minds in the university and national laboratory environments actively engaged in investigations of fundamental environmental problems? If such a beginning can be made, how should its significance be communicated to other agencies?

  5. Basic Science Evidence for the Link Between Erectile Dysfunction and Cardiometabolic Dysfunction

    PubMed Central

    Musicki, Biljana; Bella, Anthony J.; Bivalacqua, Trinity J.; Davies, Kelvin P.; DiSanto, Michael E.; Gonzalez-Cadavid, Nestor F.; Hannan, Johanna L.; Kim, Noel N.; Podlasek, Carol A.; Wingard, Christopher J.; Burnett, Arthur L.

    2016-01-01

    Introduction Although clinical evidence supports an association between cardiovascular/metabolic diseases (CVMD) and erectile dysfunction (ED), scientific evidence for this link is incompletely elucidated. Aim This study aims to provide scientific evidence for the link between CVMD and ED. Methods In this White Paper, the Basic Science Committee of the Sexual Medicine Society of North America assessed the current literature on basic scientific support for a mechanistic link between ED and CVMD, and deficiencies in this regard with a critical assessment of current preclinical models of disease. Results A link exists between ED and CVMD on several grounds: the endothelium (endothelium-derived nitric oxide and oxidative stress imbalance); smooth muscle (SM) (SM abundance and altered molecular regulation of SM contractility); autonomic innervation (autonomic neuropathy and decreased neuronal-derived nitric oxide); hormones (impaired testosterone release and actions); and metabolics (hyperlipidemia, advanced glycation end product formation). Conclusion Basic science evidence supports the link between ED and CVMD. The Committee also highlighted gaps in knowledge and provided recommendations for guiding further scientific study defining this risk relationship. This endeavor serves to develop novel strategic directions for therapeutic interventions. PMID:26646025

  6. Addressing sustainable contributions to GEO/GEOSS from Science and Technology Communities: the EGIDA Methodology

    NASA Astrophysics Data System (ADS)

    Mazzetti, P.; Nativi, S.

    2012-04-01

    The European Project EGIDA (Coordinating Earth and Environmental cross-disciplinary projects to promote GEOSS) co-funded by the European Commission under the Seventh Framework programme, has started in September 2010. It aims to prepare a sustainable process of contribution to GEO/GEOSS promoting coordination of activities carried out by: the GEO Science & Technology (S&T) Committee; S&T national and European initiatives; and other S&T Communities. This will be done by supporting broader implementation and effectiveness of the GEOSS S&T Roadmap and the GEOSS mission through coherent and interoperable networking of National and European projects, and International initiatives. The definition of a general methodology for a sustainable contribution to GEO/GEOSS through the implementation of a System-of-System (re-) engineering process is one of the objectives of the EGIDA Project in order to consolidate the results of the actions carried out in support of the GEO Science and Technology Committee (STC) Road Map. The EGIDA Methodology is based on several sources including GEO activities and documents, activities of the EGIDA project in support of the GEO STC Road Map, lessons learned from the initiatives and projects already contributing, in different ways, to the building of advanced infrastructures as direct or indirect part to GEO/GEOSS. The design of the EGIDA Methodology included several steps: a) an operational definition of the EGIDA Methodology, b) the identification of the target audience for the EGIDA Methodology, c) the identification of typical scenarios for the application of the EGIDA Methodology. Basing on these design activities the EGIDA Methodology is defined as a set of two activities running in parallel: Networking Activities - to identify and address the relevant S&T community(-ies) and actors (Community Engagement) - and Technical Activities: - to guide the infrastructure development and align it with the GEO/GEOSS interoperability principles

  7. The Neuropsychoanalytic Approach: Using Neuroscience as the Basic Science of Psychoanalysis

    PubMed Central

    Johnson, Brian; Flores Mosri, Daniela

    2016-01-01

    Neuroscience was the basic science behind Freud's psychoanalytic theory and technique. He worked as a neurologist for 20 years before being aware that a new approach to understand complex diseases, namely the hysterias, was needed. Solms coined the term neuropsychoanalysis to affirm that neuroscience still belongs in psychoanalysis. The neuropsychoanalytic field has continued Freud's original ideas as stated in 1895. Developments in psychoanalysis that have been created or revised by the neuropsychoanalysis movement include pain/relatedness/opioids, drive, structural model, dreams, cathexis, and dynamic unconscious. Neuroscience has contributed to the development of new psychoanalytic theory, such as Bazan's (2011) description of anxiety driven by unconscious intentions or “phantoms.” Results of adopting the “dual aspect monism” approach of idiographic psychoanalytic clinical observation combined with nomothetic investigation of related human phenomena include clarification and revision of theory, restoration of the scientific base of psychoanalysis, and improvement of clinical treatments. By imbricating psychoanalytic thinking with neuroscience, psychoanalysts are also positioned to make contributions to neuroscience research. Freud's original Project for a Scientific Psychology/Psychology for Neurologists can be carried forward in a way that moves psychoanalysis into the twenty-first century as a core contemporary science (Kandel, 1999). Neuroscience as the basic science of psychoanalysis both improves the field, and enhances its scientific and cultural status. PMID:27790160

  8. The United Nations Basic Space Science Initiative (UNBSSI): A Historical Introduction

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    2006-11-01

    Pursuant to recommendations of the Third United Nations Conference on the Exploration and Peaceful Uses of Outer Space (UNISPACE III) and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS), annual UN/European Space Agency workshops on basic space science have been held around the world since 1991. These workshops contributed to the development of astrophysics and space science, particularly in developing nations. Following a process of prioritization, the workshops identified the following elements as particularly important for international cooperation in the field: (i) operation of astronomical telescope facilities implementing TRIPOD, (ii) virtual observatories, (iii) astrophysical data systems, (iv) con-current design capabilities for the development of international space missions, and (v) theoretical astrophysics such as applications of non-extensive statistical mechanics. Beginning in 2005, the workshops are focusing on preparations for the International Heliophysical Year 2007 (IHY2007). The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost, ground-based, world- wide instrument arrays as led by the IHY secretariat. Wamsteker, W., Albrecht, R. and Haubold, H.J.: Developing Basic Space Science World-Wide: A Decade of UN/ESA Workshops: Kluwer Academic Publishers, Dordrecht 2004. http://ihy2007.org http://www.unoosa.org/oosa/en/SAP/bss/ihy2007/index.html http://www.cbpf.br/GrupPesq/StatisticalPhys/biblio.htm

  9. Addressing Nature of Science Core Tenets with the History of Science: An Example with Sickle-Cell Anemia & Malaria

    ERIC Educational Resources Information Center

    Howe, Erica M.

    2007-01-01

    The history of science (HOS) has proven to be a useful pedagogical tool to help students learn about what has come to be regarded as an agreed upon set of core nature of science (NOS) tenets. The following article illustrates an example of how teachers can instrumentally use the history of research on heterozygote protection in sickle-cell anemia…

  10. Addressing Next Generation Science Standards: A Method for Supporting Classroom Teachers

    ERIC Educational Resources Information Center

    Pellien, Tamara; Rothenburger, Lisa

    2014-01-01

    The Next Generation Science Standards (NGSS) will define science education for the foreseeable future, yet many educators struggle to see the bridge between current practice and future practices. The inquiry-based methods used by Extension professionals (Kress, 2006) can serve as a guide for classroom educators. Described herein is a method of…

  11. Workshop on Friction: Understanding and Addressing Students' Difficulties in Learning Science through a Hermeneutical Perspective

    ERIC Educational Resources Information Center

    Ha, Sangwoo; Lee, Gyoungho; Kalman, Calvin S.

    2013-01-01

    Hermeneutics is useful in science and science education by emphasizing the process of understanding. The purpose of this study was to construct a workshop based upon hermeneutical principles and to interpret students' learning in the workshop through a hermeneutical perspective. When considering the history of Newtonian mechanics, it could be…

  12. Bringing Climate Change into the Life Science Classroom: Essentials, Impacts on Life, and Addressing Misconceptions

    ERIC Educational Resources Information Center

    Hawkins, Amy J.; Stark, Louisa A.

    2016-01-01

    Climate change is at the forefront of our cultural conversation about science, influencing everything from presidential debates to Leonardo DiCaprio's 2016 Oscar acceptance speech. The topic is becoming increasingly socially and scientifically relevant but is no closer to being resolved. Most high school students take a life science course but…

  13. How Singapore Junior College Science Teachers Address Curriculum Reforms: A Theory

    ERIC Educational Resources Information Center

    Lim, Patrick; Pyvis, David

    2012-01-01

    Using grounded theory research methodology, a theory was developed to explain how Singapore junior college science teachers implement educational reforms underpinning the key initiatives of the "Thinking Schools, Learning Nation" policy. The theory suggests Singapore junior college science teachers "deal with" implementing…

  14. Mathematical Modeling in Science: Using Spreadsheets to Create Mathematical Models and Address Scientific Inquiry

    ERIC Educational Resources Information Center

    Horton, Robert M.; Leonard, William H.

    2005-01-01

    In science, inquiry is used as students explore important and interesting questions concerning the world around them. In mathematics, one contemporary inquiry approach is to create models that describe real phenomena. Creating mathematical models using spreadsheets can help students learn at deep levels in both science and mathematics, and give…

  15. The articulation of integration of clinical and basic sciences in concept maps: differences between experienced and resident groups.

    PubMed

    Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan

    2016-08-01

    To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic science concepts and these basic science concepts are expected to be used for the organization of the maps. These hypotheses are derived from studies about knowledge development of individuals. However, integrated curricula require a high degree of cooperation between clinicians and basic scientists. This study examined whether there are consistent variations regarding the articulation of integration when groups of experienced clinicians and basic scientists and groups of residents and basic scientists-in-training construct concept maps. Seven groups of three clinicians and basic scientists on experienced level and seven such groups on resident level constructed concept maps illuminating clinical problems. They were guided by instructions that focused them on articulation of integration. The concept maps were analysed by features that described integration. Descriptive statistics showed consistent variations between the two expertise levels. The concept maps of the resident groups exceeded those of the experienced groups in articulated integration. First, they used significantly more links between clinical and basic science concepts. Second, these links connected basic science concepts with a greater variety of clinical concepts than the experienced groups. Third, although residents did not use significantly more basic science concepts, they used them significantly more frequent to organize the clinical concepts. The conclusion was drawn that not all hypotheses could be confirmed and that the resident concept maps were more elaborate than expected. This article discusses the implications for the role that residents and

  16. The relationship between immediate relevant basic science knowledge and clinical knowledge: physiology knowledge and transthoracic echocardiography image interpretation.

    PubMed

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-10-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent research has implied that a more complex relationship between the two knowledge bases exists. In this study, we explore the relationship between immediate relevant basic science (physiology) and clinical knowledge within a specific domain of medicine (echocardiography). Twenty eight medical students in their 3rd year and 45 physicians (15 interns, 15 cardiology residents and 15 cardiology consultants) took a multiple-choice test of physiology knowledge. The physicians also viewed images of a transthoracic echocardiography (TTE) examination and completed a checklist of possible pathologies found. A total score for each participant was calculated for the physiology test, and for all physicians also for the TTE checklist. Consultants scored significantly higher on the physiology test than did medical students and interns. A significant correlation between physiology test scores and TTE checklist scores was found for the cardiology residents only. Basic science knowledge of immediate relevance for daily clinical work expands with increased work experience within a specific domain. Consultants showed no relationship between physiology knowledge and TTE interpretation indicating that experts do not use basic science knowledge in routine daily practice, but knowledge of immediate relevance remains ready for use.

  17. Peer-assisted learning: filling the gaps in basic science education for preclinical medical students.

    PubMed

    Sammaraiee, Yezen; Mistry, Ravi D; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth

    2016-09-01

    In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United Kingdom medical school. Twenty tutorials were delivered by senior students throughout the year to first- and second-year students. A baseline questionnaire was delivered to inform the development of the program followed by an end-point questionnaire the next year (n = 122). Quizzes were administered before and after five separate tutorials to assess changes in mean student scores. Additionally, each tutorial was evaluated via a questionnaire for participants (n = 949). All five posttutorial quizzes showed a significant improvement in mean student score (P < 0.05). Questionnaires showed students found the program to be relevant and useful for revision purposes and appreciated how tutorials contextualized basic science to clinical medicine. Students appreciated the interactive nature of the sessions and found receiving personalized feedback about their learning and consolidating information with someone familiar with the material to be useful. With the inclusion of the program, students felt there were now an adequate number of tutorials during the year. In conclusion, this study shows that senior medical students can design and deliver a program that adds value to the mostly lecture-based formal preclinical curriculum. We hope that our study can prompt further work to explore the effect of PAL on the teaching of basic sciences during preclinical studies.

  18. [Three-dimensional cell cultures. Applications in basic science and biotechnology].

    PubMed

    Kitel, Radosław; Czarnecka, Joanna; Rusin, Aleksandra

    2013-01-01

    The tissue culture technique is widely used in biochemical and molecular studies, offering accessibility to biological material, high reproducibility of results and high throughput format, comparing with organ cultures. However, traditional, two-dimensional cultures (2D cultures) poorly represent the microenvironment of a tissue, and they are gradually replaced with 3D cultures, that enable formation of intercellular contacts, signaling pathways and gene expression characteristic for tissue in vivo. This paper presents the biology of three-dimensional cultures (spheroids), their applications in basic science and biotechnology and methods of spheroids formation.

  19. Toward Control of Matter: Basic Energy Science Needs for a New Class of X-Ray Light Sources

    SciTech Connect

    Arenholz, Elke; Belkacem, Ali; Cocke, Lew; Corlett, John; Falcone, Roger; Fischer, Peter; Fleming, Graham; Gessner, Oliver; Hasan, M. Zahid; Hussain, Zahid; Kevan, Steve; Kirz, Janos; McCurdy, Bill; Nelson, Keith; Neumark, Dan; Nilsson, Anders; Siegmann, Hans; Stocks, Malcolm; Schafer, Ken; Schoenlein, Robert; Spence, John; Weber, Thorsten

    2008-09-24

    Over the past quarter century, light-source user facilities have transformed research in areas ranging from gas-phase chemical dynamics to materials characterization. The ever-improving capabilities of these facilities have revolutionized our ability to study the electronic structure and dynamics of atoms, molecules, and even the most complex new materials, to understand catalytic reactions, to visualize magnetic domains, and to solve protein structures. Yet these outstanding facilities still have limitations well understood by their thousands of users. Accordingly, over the past several years, many proposals and conceptual designs for"next-generation" x-ray light sources have been developed around the world. In order to survey the scientific problems that might be addressed specifically by those new light sources operating below a photon energy of about 3 keV and to identify the scientific requirements that should drive the design of such facilities, a workshop"Science for a New Class of Soft X-Ray Light Sources" was held in Berkeley in October 2007. From an analysisof the most compelling scientific questions that could be identified and the experimental requirements for answering them, we set out to define, without regard to the specific technologies upon which they might be based, the capabilities such light sources would have to deliver in order to dramatically advance the state of research in the areas represented in the programs of the Department of Energy's Office of Basic Energy Sciences (BES). This report is based on the workshop presentations and discussions.

  20. Addressing the Process Improvement Science Knowledge and Skills of Program Directors and Associate Program Directors

    PubMed Central

    Gravdal, Judith A.; Hyziak, Pamela; Belmonte, Frank; Clemens, Mary Ann; Sulo, Suela

    2015-01-01

    Background Process improvement (PI) science is relatively new to healthcare and has only recently been introduced to medical education. Most residency faculty lack training or experience in PI science activities. We assessed the impact of PI science education on the knowledge and attitudes of a group of residency and fellowship program directors and associate program directors using their respective Accreditation Council for Graduate Medical Education annual program evaluations (APEs) as an experiential object. Methods For this pre/post study, 16 program directors and 7 associate program directors were surveyed before and after 4 didactic modules. The APEs for the 2 years prior to the intervention and in the fall after the intervention were analyzed. Mentoring in the use of these skills in the preparation of the APEs was provided. Results The participants demonstrated improved knowledge in some areas and increased awareness of deficits in other areas. APE quality did not show consistent improvement following the intervention. Conclusion The PI science knowledge and skill gaps of program directors and associate program directors are likely to impact the content and success of residency curricula. The designed PI science curriculum was slightly effective. Using the APE as the experiential object was convenient, but the APE was not the best project for a PI exercise. New, effective strategies and interventions to develop expertise in PI science are important as programs grapple with meeting new requirements, ensuring quality programs, and preparing residents and fellows for practice. PMID:25829878

  1. Use of the National Ignition Facility for defense, energy, and basic research science

    SciTech Connect

    Logan, B.G.

    1994-07-15

    On January 15, 1993, the Department of Energy (DOE) approved the Justification for Mission Need (JMN) for the National Ignition Facility (NIF). This action (Key Decision Zero, or KD0) commenced the conceptual design for the facility, which has resulted in a recently completed Conceptual Design Report (CDR). The JMN document defined the NIF mission elements to include laboratory fusion ignition and energy gain, weapons physics, and nuclear weapons effects testing research (NWET). NIF has a dual benefit by contributing to inertial fusion energy (IFE), industrial technology development, new basic science areas applying high power lasers, and training young scientists for future stewardship activities. For consideration of the next DOE action, Key Decision One (KD1), all mission elements of the NIF as stated in the JMN are consistent with and important to the US stockpile stewardship program, and are expected to continue to be in the vital interest of the United States for the long term. This document provides further information on the utility of NIF for stockpile stewardship, including support for a Comprehensive Test Ban Treaty (CTBT), and specific findings of four national workshops on the NIF utility for weapons physics, NWET, IFE and basic science research. The role of NIF for stockpile stewardship has been refined since a DOE meeting in Albuquerque, NM Feb. 1--2, 1994. The possible compliance of NIF research with anticipated CTBT and NPT limitations was discussed at the DOE Office of Arms Control and Nonproliferation in Washington, DC on March 8, 1994.

  2. Restructuring a basic science course for core competencies: an example from anatomy teaching.

    PubMed

    Gregory, Jeremy K; Lachman, Nirusha; Camp, Christopher L; Chen, Laura P; Pawlina, Wojciech

    2009-09-01

    Medical schools revise their curricula in order to develop physicians best skilled to serve the public's needs. To ensure a smooth transition to residency programs, undergraduate medical education is often driven by the six core competencies endorsed by the Accreditation Council for Graduate Medical Education (ACGME): patient care, medical knowledge, practice-based learning, interpersonal skills, professionalism, and systems-based practice. Recent curricular redesign at Mayo Medical School provided an opportunity to restructure anatomy education and integrate radiology with first-year gross and developmental anatomy. The resulting 6-week (120-contact-hour) human structure block provides students with opportunities to learn gross anatomy through dissection, radiologic imaging, and embryologic correlation. We report more than 20 educational interventions from the human structure block that may serve as a model for incorporating the ACGME core competencies into basic science and early medical education. The block emphasizes clinically-oriented anatomy, invites self- and peer-evaluation, provides daily formative feedback through an audience response system, and employs team-based learning. The course includes didactic briefing sessions and roles for students as teachers, leaders, and collaborators. Third-year medical students serve as teaching assistants. With its clinical focus and competency-based design, the human structure block connects basic science with best-practice clinical medicine.

  3. An elective course on the basic and clinical sciences aspects of vitamins and minerals.

    PubMed

    Islam, Mohammed A

    2013-02-12

    Objective. To develop and implement an elective course on vitamins and minerals and their usefulness as dietary supplements. Design. A 2-credit-hour elective course designed to provide students with the most up-to-date basic and clinical science information on vitamins and minerals was developed and implemented in the doctor of pharmacy (PharmD) curriculum. In addition to classroom lectures, an active-learning component was incorporated in the course in the form of group discussion. Assessment. Student learning was demonstrated by examination scores. Performance on pre- and post-course surveys administered in 2011 demonstrated a significant increase in students' knowledge of the basic and clinical science aspects of vitamins and minerals, with average scores increasing from 61% to 86%. At the end of the semester, students completed a standard course evaluation. Conclusion. An elective course on vitamin and mineral supplements was well received by pharmacy students and helped them to acquire knowledge and competence in patient counseling regarding safe, appropriate, effective, and economical use of these products.

  4. Integration of Basic and Clinical Science Courses in US PharmD Programs.

    PubMed

    Islam, Mohammed A; Talukder, Rahmat M; Taheri, Reza; Blanchard, Nicholas

    2016-12-25

    Objective. To determine the current status of and faculty perceptions regarding integration of basic and clinical science courses in US pharmacy programs. Methods. A 25-item survey instrument was developed and distributed to 132 doctor of pharmacy (PharmD) programs. Survey data were analyzed using Mann-Whitney U test or Kruskal-Wallis test. Thematic analysis of text-based comments was performed using the constant comparison method. Results. One hundred twelve programs responded for a response rate of 85%. Seventy-eight (70%) offered integrated basic and clinical science courses. The types of integration included: full integration with merging disciplinary contents (n=25), coordinated delivery of disciplinary contents (n=50), and standalone courses with integrated laboratory (n=3). Faculty perceptions of course integration were positive. Themes that emerged from text-based comments included positive learning experiences as well as the challenges, opportunities, and skepticism associated with course integration. Conclusion. The results suggest wide variations in the design and implementation of integrated courses among US pharmacy programs. Faculty training and buy-in play a significant role in successful implementation of curricular integration.

  5. Integration of Basic and Clinical Science Courses in US PharmD Programs

    PubMed Central

    Talukder, Rahmat M.; Taheri, Reza; Blanchard, Nicholas

    2016-01-01

    Objective. To determine the current status of and faculty perceptions regarding integration of basic and clinical science courses in US pharmacy programs. Methods. A 25-item survey instrument was developed and distributed to 132 doctor of pharmacy (PharmD) programs. Survey data were analyzed using Mann-Whitney U test or Kruskal-Wallis test. Thematic analysis of text-based comments was performed using the constant comparison method. Results. One hundred twelve programs responded for a response rate of 85%. Seventy-eight (70%) offered integrated basic and clinical science courses. The types of integration included: full integration with merging disciplinary contents (n=25), coordinated delivery of disciplinary contents (n=50), and standalone courses with integrated laboratory (n=3). Faculty perceptions of course integration were positive. Themes that emerged from text-based comments included positive learning experiences as well as the challenges, opportunities, and skepticism associated with course integration. Conclusion. The results suggest wide variations in the design and implementation of integrated courses among US pharmacy programs. Faculty training and buy-in play a significant role in successful implementation of curricular integration. PMID:28179715

  6. An overview of digital spectrometers for MR imaging. Instrumentation Subcommittee of the SMRI Basic Science Council.

    PubMed

    Holland, G N; MacFall, J R

    1992-01-01

    Most magnetic resonance (MR) imaging systems were originally designed with analog spectrometers, since that was the "state of the art" in the late 1970s, when they were developed. Advances in technology have allowed the design of radio-frequency electronics with a much larger percentage of digital components while the cost of such components has decreased. This has given manufacturers the incentive to develop new spectrometers that incorporate these electronics for cost reduction and potentially better performance. Upgrades and new models of MR units have become available with these so-called "digital spectrometers." Because of the interest in the new systems, the Instrumentation Subcommittee of the Basic Science Council of the Society for Magnetic Resonance Imaging has produced this report to review the basic features of analog and digital spectrometers to help the MR imaging community better understand the similarities and differences of these systems. Some details of actual commercial implementations were left out to focus on the basic features. Regardless, the authors hope they have provided a readable introduction to this important topic.

  7. MAEA Interactive Science Programs: An Innovative Approach to Address the Under-representation of Minorities and Women in Science, Math, and Technological Fields.

    NASA Astrophysics Data System (ADS)

    Holloman, E. L.; Baynes, D. L.

    2004-12-01

    Minority Aviation Education Association Inc. (MAEA) was founded in 1992 by Darryl Lee Baynes to address the under-representation of minorities and women in all science, math, and technological fields. The organization is committed to exposing minorities and women to science, math, and technology in grades K-12. The first objective of MAEA is to educate teachers on how to integrate hands-on experiments in their class and include inquiry based learning in their science curriculum. A second objective is to educate students, teachers, and the community regarding the history of minorities in the fields of science, math, and technology, in order to provide role models in these fields. The last objective is to demonstrate the relevance of science in everyday life, with the intention of stimulating future career interest in the fields of science, math, and technology. MAEA currently offers more than 70 hands on inquiry-based programs that are aligned with the 2061 Bench Marks and National Science Standards. The programs are divided into four main categories: auditorium/classroom, enrichment and outreach, after school, and professional development. For the last 14 years, MAEA has served communities and schools across the country with remarkable success and therefore offers an alternative model for K-12 science education. This alternative is significant to the scientific community because it links the under-served population to an active academic and professional pipeline.

  8. Assessment of knowledge and perceptions toward generic medicines among basic science undergraduate medical students at Aruba

    PubMed Central

    Shankar, P. Ravi; Herz, Burton L.; Dubey, Arun K.; Hassali, Mohamed A.

    2016-01-01

    Objective: Use of generic medicines is important to reduce rising health-care costs. Proper knowledge and perception of medical students and doctors toward generic medicines are important. Xavier University School of Medicine in Aruba admits students from the United States, Canada, and other countries to the undergraduate medical (MD) program. The present study was conducted to study the knowledge and perception about generic medicines among basic science MD students. Materials and Methods: The cross-sectional study was conducted among first to fifth semester students during February 2015. A previously developed instrument was used. Basic demographic information was collected. Respondent’s agreement with a set of statements was noted using a Likert-type scale. The calculated total score was compared among subgroups of respondents. One sample Kolmogorov–Smirnov test was used to study the normality of distribution, Independent samples t-test to compare the total score for dichotomous variables, and analysis of variance for others were used for statistical analysis. Results: Fifty-six of the 85 students (65.8%) participated. Around 55% of respondents were between 20 and 25 years of age and of American nationality. Only three respondents (5.3%) provided the correct value of the regulatory bioequivalence limits. The mean total score was 43.41 (maximum 60). There was no significant difference in scores among subgroups. Conclusions: There was a significant knowledge gap with regard to the regulatory bioequivalence limits for generic medicines. Respondents’ level of knowledge about other aspects of generic medicines was good but could be improved. Studies among clinical students in the institution and in other Caribbean medical schools are required. Deficiencies were noted and we have strengthened learning about generic medicines during the basic science years. PMID:28031604

  9. International cooperation in basic space science, Western Asian countries and the world

    NASA Astrophysics Data System (ADS)

    de Morais Mendonca Teles, Antonio

    The world will never better develop and attain a global peace state, if it does not exist a world-wide cooperation, union of interests among all countries on planet Earth, respecting and understanding each other culture differences. So, if the countries interested in space science want to create or better develop this field, they need to firstly construct peace states and social cooperation, while scientific and technological cooperation will develop -among them. Here in this paper, under the principles in the United Nations (UN)' Agenda 21 (UN UNCED, 1992), I propose four points that can lead to a practical and solid international cooperation in basic aerospace science and technology, based on ground studies, with sustainable space programs in countries with social necessities, and to the construction of an avenue of peace states in those areas and in the world, 1) The creation of LINKS among the "developing" countries, among the "developed" ones and between them -with scientists, engineers, educators and administrative personnel. This can catalyze a self-sustainable scientific and technological production in the "developing" countries. Financial matters could be done through the World Bank in coopera-tion with UNESCO. 2) The administration of this difficult enterprise of international coopera-tion. With the increasing complexity of relationships among the aerospace-interested countries, it will be necessary the creation of a center capable to serve as an INTERNATIONAL CO-ORDINATOR CENTER FOR AEROSPACE ACTIVITIES. 3) CULTURE: in Western Asian countries there is a cultural habit that when somebody gives something valuable to a person, this person should give something back. Thus, the Western Asian countries receiving infor-mation on basic aerospace science and technology from the "developed" ones, those countries would probably feel they should give something in return. Western Asian countries could trans-mit their costumes, thinking ways, habits, persons' worries

  10. The Views of Science Pre-Service Teachers about the Usage of Basic Information Technologies (BIT) in Education and Instruction

    ERIC Educational Resources Information Center

    Çetin, Oguz

    2016-01-01

    In this study aiming to present a description based on science pre-service teachers' views related to use of Basic Information Technologies (BIT) in education and training, an interview is carried out with 21 pre-service science teachers who study in different classes in Faculty of Education, Nigde University. For this aim, improved interview form…

  11. Addressing the Dynamics of Science in Curricular Reform for Scientific Literacy: The Case of Genomics

    ERIC Educational Resources Information Center

    van Eijck, Michiel

    2010-01-01

    Science education reform must anticipate the scientific literacy required by the next generation of citizens. Particularly, this counts for rapidly emerging and evolving scientific disciplines such as genomics. Taking this discipline as a case, such anticipation is becoming increasingly problematic in today's knowledge societies in which the…

  12. Resources Needed for Addressing Common Core Standards in Mathematics, Language Arts and Next Generation Science Standards

    ERIC Educational Resources Information Center

    Cozzens, Margaret B.

    2015-01-01

    There is a vital need in the mathematics and science teaching and learning community at the secondary school level for assistance for teachers in adapting curricular materials to meet the many district, state, and national demands and to facilitate high-quality learning of students and their ability to transfer this learning and apply it as they…

  13. Addressing Challenges to Public Understanding of Science: Epistemic Cognition, Motivated Reasoning, and Conceptual Change

    ERIC Educational Resources Information Center

    Sinatra, Gale M.; Kienhues, Dorothe; Hofer, Barbara K.

    2014-01-01

    Science is of critical importance to daily life in a knowledge society and has a significant influence on many everyday decisions. As scientific problems increase in their number and complexity, so do the challenges facing the public in understanding these issues. Our objective is to focus on 3 of those challenges: the challenge of reasoning about…

  14. De-Marginalizing Science in the Elementary Classroom by Coaching Teachers to Address Perceived Dilemmas

    ERIC Educational Resources Information Center

    Berg, Alissa; Mensah, Felicia Moore

    2014-01-01

    This study identifies and explores the dilemmas experienced by three first-grade teachers in teaching elementary school science. The impact of coaching and teachers' career stages on how teachers reconcile their dilemmas was examined. Results of this comparative case study indicate teachers perceived tensions between focusing instructional…

  15. From Professional Development to Classroom Instruction: Addressing Issues Related to Science Inquiry Discourse

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.

    2009-01-01

    In this rejoinder, I first provide a more detailed account of the discourse-focused professional development activities facilitated as part of the SMIT'N program, specifically addressing issues raised by van Zee with regard to the institute's overall format, goals and development strategies. Next, I resort to Peter Medawar's metaphorical view of…

  16. How neuroscience is taught to North American dental students: results of the Basic Science Survey Series.

    PubMed

    Gould, Douglas J; Clarkson, Mackenzie J; Hutchins, Bob; Lambert, H Wayne

    2014-03-01

    The purpose of this study was to determine how North American dental students are taught neuroscience during their preclinical dental education. This survey represents one part of a larger research project, the Basic Science Survey Series for Dentistry, which covers all of the biomedical science coursework required of preclinical students in North American dental schools. Members of the Section on Anatomical Sciences of the American Dental Education Association assembled, distributed, and analyzed the neuroscience survey, which had a 98.5 percent response from course directors of the sixty-seven North American dental schools. The eighteen-item instrument collected demographic data on the course directors, information on the content in each course, and information on how neuroscience content is presented. Findings indicate that 1) most neuroscience instruction is conducted by non-dental school faculty members; 2) large content variability exists between programs; and 3) an increase in didactic instruction, integrated curricula, and use of computer-aided instruction is occurring. It is anticipated that the information derived from the survey will help guide neuroscience curricula in dental schools and aid in identifying appropriate content.

  17. Embryology and histology education in North American dental schools: the Basic Science Survey Series.

    PubMed

    Burk, Dorothy T; Lee, Lisa M J; Lambert, H Wayne

    2013-06-01

    As part of the Basic Science Survey Series (BSSS) for Dentistry, members of the American Dental Education Association (ADEA) Anatomical Sciences Section surveyed faculty members teaching embryology and histology courses at North American dental schools. The survey was designed to assess, among other things, curriculum content, utilization of laboratories, use of computer-assisted instruction (CAI), and recent curricular changes. Responses were received from fifty-nine (88.1 percent) of the sixty-seven U.S. and Canadian dental schools. Findings suggest the following: 1) a trend toward combining courses is evident, though the integration was predominantly discipline-based; 2) embryology is rarely taught as a stand-alone course, as content is often covered in gross anatomy, oral histology, and/or in an integrated curriculum; 3) the number of contact hours in histology is decreasing; 4) a trend toward reduction in formal laboratory sessions, particularly in embryology, is ongoing; and 5) use of CAI tools, including virtual microscopy, in both embryology and histology has increased. Additionally, embryology and histology content topic emphasis is identified within this study. Data, derived from this study, may be useful to new instructors, curriculum and test construction committees, and colleagues in the anatomical sciences, especially when determining a foundational knowledge base.

  18. Review of the Lujan neutron scattering center: basic energy sciences prereport February 2009

    SciTech Connect

    Hurd, Alan J; Rhyne, James J; Lewis, Paul S

    2009-01-01

    The Lujan Neutron Scattering Center (Lujan Center) at LANSCE is a designated National User Facility for neutron scattering and nuclear physics studies with pulsed beams of moderated neutrons (cold, thermal, and epithermal). As one of five experimental areas at the Los Alamos Neutron Science Center (LANSCE), the Lujan Center hosts engineers, scientists, and students from around the world. The Lujan Center consists of Experimental Room (ER) 1 (ERl) built by the Laboratory in 1977, ER2 built by the Office of Basic Energy Sciences (BES) in 1989, and the Office Building (622) also built by BES in 1989, along with a chem-bio lab, a shop, and other out-buildings. According to a 1996 Memorandum of Agreement (MOA) between the Defense Programs (DP) Office of the National Nuclear Security Agency (NNSA) and the Office of Science (SC, then the Office of Energy Research), the Lujan Center flight paths were transferred from DP to SC, including those in ERI. That MOA was updated in 2001. Under the MOA, NNSA-DP delivers neutron beam to the windows of the target crypt, outside of which BES becomes the 'landlord.' The leveraging nature of the Lujan Center on the LANSCE accelerator is a substantial annual leverage to the $11 M BES operating fund worth approximately $56 M operating cost of the linear accelerator (LINAC)-in beam delivery.

  19. Science as Knowledge, Practice, and Map Making: The Challenge of Defining Metrics for Evaluating and Improving DOE-Funded Basic Experimental Science

    SciTech Connect

    Bodnarczuk, M.

    1993-03-01

    Industrial R&D laboratories have been surprisingly successful in developing performance objectives and metrics that convincingly show that planning, management, and improvement techniques can be value-added to the actual output of R&D organizations. In this paper, I will discuss the more difficult case of developing analogous constructs for DOE-funded non-nuclear, non-weapons basic research, or as I will refer to it - basic experimental science. Unlike most industrial R&D or the bulk of applied science performed at the National Renewable Energy Laboratory (NREL), the purpose of basic experimental science is producing new knowledge (usually published in professional journals) that has no immediate application to the first link (the R) of a planned R&D chain. Consequently, performance objectives and metrics are far more difficult to define. My claim is that if one can successfully define metrics for evaluating and improving DOE-funded basic experimental science (which is the most difficult case), then defining such constructs for DOE-funded applied science should be much less problematic. With the publication of the DOE Standard - Implementation Guide for Quality Assurance Programs for Basic and Applied Research (DOE-ER-STD-6001-92) and the development of a conceptual framework for integrating all the DOE orders, we need to move aggressively toward the threefold next phase: (1) focusing the management elements found in DOE-ER-STD-6001-92 on the main output of national laboratories - the experimental science itself; (2) developing clearer definitions of basic experimental science as practice not just knowledge; and (3) understanding the relationship between the metrics that scientists use for evaluating the performance of DOE-funded basic experimental science, the management elements of DOE-ER-STD-6001-92, and the notion of continuous improvement.

  20. The Cognitive Outcome in the Physical Games at the College of Students of the Basic Science in the World Islamic Sciences and Education University

    ERIC Educational Resources Information Center

    Salameh, Ibrahim A. M.; Al-Maharmeh, Yaseen A. M.; Oudat, Mo'een A.

    2013-01-01

    The study aimed at reconnoitering the cognitive outcome in the physical games at students of the college of basic science in the World Islamic Science and Education University. The descriptive method was employed, where the sample was randomly chosen, and amounted to (16) students (males & females) from the faculty. The sample discussed five…

  1. The Divergent Thinking of Basic Skills of Sciences Process Skills of Life Aspects on Natural Sciences Subject in Indonesian Elementary School Students

    ERIC Educational Resources Information Center

    Subali, Bambang; Paidi; Mariyam, Siti

    2016-01-01

    This research aims at measuring the divergent thinking of basic skills of science process skills (SPS) of life aspects in Natural Sciences subjects on Elementary School. The test instruments used in this research have been standardized through the development of instruments. In this case, the tests were tried out to 3070 students. The results of…

  2. Process Improvement: Addressing Attrition from the Uniformed Services University of the Health Sciences Nurse Anesthesia Program.

    PubMed

    Wilson, John Tyler; Gibbons, Susanne W; Wofford, Kenneth

    2015-10-01

    This retrospective cohort study examined the Uniformed Services University of the Health Sciences Registered Nurse Anesthesia program to identify reasons for high attrition rates. Relevant data were examined for 180 students enrolled in classes from 2005 through 2011. During that period, 40 students were dismissed or disenrolled, with the highest attrition rate (35%) occurring in the class of 2010. Evidence from this investigation indicates students who completed the program were younger, earned higher grade point averages while completing their undergraduate bachelor of science in nursing, and achieved higher analytic and total Graduate Record Examination scores than did students who withdrew or were dismissed. Gender differences were noted, as a greater proportion of women completed the program compared with men. Personal, family, and other issues frequently overlapped, with academic performance problems leading to attrition. Based on these findings, a number of important changes were made in the admission process to the USUHS RNA program and in the nonacademic mentoring and assistance offered to students.

  3. What works to address prejudice? Look to developmental science research for the answer.

    PubMed

    Killen, Melanie; Mulvey, Kelly Lynn; Hitti, Aline; Rutland, Adam

    2012-12-01

    Developmental perspectives on prejudice provide a fundamental and important key to the puzzle for determining how to address prejudice. Research with historically disadvantaged and advantaged groups in childhood and adolescence reveals the complexity of social cognitive and moral judgments about prejudice, discrimination, bias, and exclusion. Children are aware of status and hierarchies, and often reject the status quo. Intervention, to be effective, must happen early in development, before prejudice and stereotypes are deeply entrenched.

  4. Cartilage repair: synthetics and scaffolds: basic science, surgical techniques, and clinical outcomes.

    PubMed

    Kerker, Jordan T; Leo, Andrew J; Sgaglione, Nicholas A

    2008-12-01

    Symptomatic articular cartilage lesions have gained attention and clinical interest in recent years and can be difficult to treat. Historically, various biologic surgical treatment options have yielded inconsistent results because of the inferior biomechanical properties associated with a variable healing response. Improving technology and surgical advances has generated considerable research in cartilage resurfacing and optimizing hyaline tissue restoration. Biologic innovation and tissue engineering in cartilage repair have used matrix scaffolds, autologous and allogenic chondrocytes, cartilage grafts, growth factors, stem cells, and genetic engineering. Numerous evolving technologies and surgical approaches have been introduced into the clinical setting. This review will discuss the basic science, surgical techniques, and clinical outcomes of novel synthetic materials and scaffolds for articular cartilage repair.

  5. The role of cardiac PET in translating basic science into the clinical arena.

    PubMed

    Bravo, Paco E; Bengel, Frank M

    2011-08-01

    Non-invasive imaging has become fundamental in translating findings from basic science research into clinical applications. In this aspect, positron-emission tomography (PET) offers important advantages over other common imaging modalities like single-photon emission computed tomography, computed tomography, and magnetic resonance imaging (MRI), since PET provides superior detection sensitivity in the evaluation of different cardiovascular targets and pathways at the cellular and subcellular level, and because it is a well-established technique for absolute image quantification. The development and the introduction of dedicated small animal PET systems have greatly facilitated and contributed to advancements in the translation of novel radio-labeled compounds from experimental to clinical practice. The scope of the present article is to review the most relevant and successful PET applications in cardiovascular translational research.

  6. Regenerative dentistry: translating advancements in basic science research to the dental practice.

    PubMed

    Garcia-Godoy, Franklin; Murray, Peter

    2010-01-01

    Scientific advances in the creation of restorative biomaterials, in vitro cell culture technology, tissue engineering, molecular biology and the human genome project provide the basis for the introduction of new technologies into dentistry. This review provides an assessment of how tissue engineering, stem cell, genetic transfer, biomaterial and growth factor therapies can be integrated into clinical dental therapies to restore and regenerate oral tissues. In parallel to the creation of a new field in general medicine called "regenerative medicine," we call this field "regenerative dentistry." While the problems of introducing regenerative therapies are substantial, the potential benefits to patients and the profession are equally ground-breaking. In this review, we outline a few areas of interest for the future of oral and dental medicine in which advancements in basic science have already been adapted to fit the goals of 21st century dentistry.

  7. [Evolution of the number of authors in clinical and basic science journals in the Spanish language].

    PubMed

    Soteras, F; Blanco, J R; García Pineda, A F; Rupérez, H; Córdova, A; Escanero, J F

    1990-01-01

    The number of signing authors in Revista Clínica Española. Revista Española de Fisiología and Revista Española de Oncología have been analyzed from their first to the last received issue. The results obtained show an increasing number of authors in all journals specially during the 70s. The results also point out a relative decrease in the number of authors in basic sciences in relation to clinical publications. The increase in the number of authors in The Revista Española de Oncología has started somewhat later than the others. The environmental and professional stress as well as the interrelations between different hospital members have been suggested, amongst others, as the possible cause of these events.

  8. Laser-driven electron beam and radiation sources for basic, medical and industrial sciences.

    PubMed

    Nakajima, Kazuhisa

    2015-01-01

    To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker's review article on "Laser Acceleration and its future" [Toshiki Tajima, (2010)],(1)) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated.

  9. Laser-driven electron beam and radiation sources for basic, medical and industrial sciences

    PubMed Central

    NAKAJIMA, Kazuhisa

    2015-01-01

    To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker’s review article on “Laser Acceleration and its future” [Toshiki Tajima, (2010)],1) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated. PMID:26062737

  10. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    PubMed Central

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2012-01-01

    Objective To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in three high-risk clinical populations. Our theoretically-derived intervention comprised a combination of positive affect and self-affirmation (PA/SA) which we applied to three clinical chronic disease populations. Methods We employed a sequential mixed methods model (EVOLVE) to design and test the PA/SA intervention in order to increase physical activity in people with coronary artery disease (post-percutaneous coronary intervention [PCI]) or asthma (ASM), and to improve medication adherence in African Americans with hypertension (HTN). In an initial qualitative phase, we explored participant values and beliefs. We next pilot tested and refined the intervention, and then conducted three randomized controlled trials (RCTs) with parallel study design. Participants were randomized to combined PA/SA vs. an informational control (IC) and followed bimonthly for 12 months, assessing for health behaviors and interval medical events. Results Over 4.5 years, we enrolled 1,056 participants. Changes were sequentially made to the intervention during the qualitative and pilot phases. The three RCTs enrolled 242 PCI, 258 ASM and 256 HTN participants (n=756). Overall, 45.1% of PA/SA participants versus 33.6% of IC participants achieved successful behavior change (p=0.001). In multivariate analysis PA/SA intervention remained a significant predictor of achieving behavior change (p<0.002, OR=1.66, 95% CI 1.22–2.27), controlling for baseline negative affect, comorbidity, gender, race/ethnicity, medical events, smoking and age. Conclusions The EVOLVE method is a means by which basic behavioral science research can be translated into efficacious interventions for chronic disease populations. PMID:22963594

  11. Using Next Generation Science Standards (NGSS) Practices to Address Scientific Misunderstandings Around Complex Environmental Issues

    NASA Astrophysics Data System (ADS)

    Turrin, M.; Kenna, T. C.

    2014-12-01

    The new NGSS provide an important opportunity for scientists to develop curriculum that links the practice of science to research-based data in order to improve understanding in areas of science that are both complex and confusing. Our curriculum focuses in particular on the fate and transport of anthropogenic radionuclides. Radioactivity, both naturally occurring and anthropogenic, is highly debated and largely misunderstood, and for large sections of the population is a source of scientific misunderstanding. Developed as part of the international GEOTRACES project which focuses on identifying ocean processes and quantifying fluxes that control the distributions of selected trace elements and isotopes in the ocean, and on establishing the sensitivity of these distributions to changing environmental conditions, the curriculum topic fits nicely into the applied focus of NGSS with both environmental and topical relevance. Our curriculum design focuses on small group discussion driven by questions, yet unlike more traditional curriculum pieces these are not questions posed to the students, rather they are questions posed by the students to facilitate their deeper understanding. Our curriculum design challenges the traditional question/answer memorization approach to instruction as we strive to develop an educational approach that supports the practice of science as well as the NGSS Cross Cutting Concepts and the Science & Engineering Practices. Our goal is for students to develop a methodology they can employ when faced with a complex scientific issue. Through background readings and team discussions they identify what type of information is important for them to know and where to find a reliable source for that information. Framing their discovery around key questions such as "What type of radioactive decay are we dealing with?", "What is the potential half-life of the isotope?", and "What are the pathways of transport of radioactivity?" allows students to evaluate a

  12. Pharmacology education in North American dental schools: the basic science survey series.

    PubMed

    Gautam, Medha; Shaw, David H; Pate, Ted D; Lambert, H Wayne

    2013-08-01

    As part of the Basic Science Survey Series (BSSS) for Dentistry, members of the American Dental Education Association (ADEA) Physiology, Pharmacology, and Therapeutics Section surveyed course directors of basic pharmacology courses in North American dental schools. The survey was designed to assess, among other things, faculty affiliation and experience of course directors, teaching methods, general course content and emphasis, extent of interdisciplinary (shared) instruction, and impact of recent curricular changes. Responses were received from forty-nine of sixty-seven (73.1 percent) U.S. and Canadian dental schools. The findings suggest the following: 1) substantial variation exists in instructional hours, faculty affiliation, placement within curriculum, class size, and interdisciplinary nature of pharmacology courses; 2) pharmacology course content emphasis is similar among schools; 3) the number of contact hours in pharmacology has remained stable over the past three decades; 4) recent curricular changes were often directed towards enhancing the integrative and clinically relevant aspects of pharmacology instruction; and 5) a trend toward innovative content delivery, such as use of computer-assisted instruction applications, is evident. Data, derived from this study, may be useful to pharmacology course directors, curriculum committees, and other dental educators with an interest in integrative and interprofessional education.

  13. International Space Science Programs: Basic Research with a High Public Purpose

    NASA Astrophysics Data System (ADS)

    Baker, D. N.

    2009-04-01

    The exploration of outer space, and the use of platforms in space to monitor the Earth, are increasingly international enterprises. The spacefaring nations of the world have programs to study the moon, the Sun, the other planets of the solar system, and the universe beyond. Space is also the domain from which navigation, communication, reconnaissance, and resource management functions are carried out by civilian and military agencies. Recent decades of experience have shown the immense benefits of international cooperation to pursue scientific research goals. In turn, the products of such basic research have immense potential to improve space situational awareness and to mitigate the effects of ''space weather'' on human technology. A key to future success of space exploration is to minimize the impacts of laws and regulations such as ITAR (International Traffic in Arms Regulations) that have already had a devastating effect on space commerce and basic space research. In this presentation I discuss the conduct of forefront science in the context of sensible, prudent international space policy and evolving governmental regulations.

  14. eGY-Africa: addressing the digital divide for science in Africa

    NASA Astrophysics Data System (ADS)

    Petitdidier, Monique; Barton, Charles; Chukwuma, Victor; Cottrell, Les

    2010-05-01

    As the world of science becomes increasingly Internet-dependent, so the African scientists become increasingly isolated. eGY-Africa is a bottom-up initiative by African scientists and their collaborators to try to reduce this digital divide by a campaign of advocacy for better institutional facilities. The present status of Internet services, problems, and plans are being mapped via a combination of a survey questionnaire-based survey and direct measurement of Internet performance (the PingER Project). Information is being gathered on policy statements and initiatives aimed at reducing the Digital Divide. eGY-Africa is establishing National groups of concerned scientists and engaging with those initiatives with related goals. Finally, and perhaps most important of all, eGY-Africa is seeking to engage with the many other programs, initiatives, and bodies that share the goal of reducing the Digital Divide - either as a direct policy objective, or indirectly as a means to an end, such as the development of capabilities in science and technology in Africa. The expectation is that informed opinion from the scientific community at the institutional, national, and international levels can be used to influence the decision makers and donors who are in a position to deliver better Internet capabilities.

  15. Shaping NASA's Earth Science Enterprise Workforce Development Initiative to Address Industry Needs

    NASA Technical Reports Server (NTRS)

    Rosage, David; Meeson, Blanche W. (Technical Monitor)

    2001-01-01

    It has been well recognized that the commercial remote sensing industry will expand in new directions, resulting in new applications, thus requiring a larger, more skilled workforce to fill the new positions. In preparation for this change, NASA has initiated a Remote Sensing Professional Development Program to address the workforce needs of this emerging industry by partnering with the private sector, academia, relevant professional societies, and other R&D organizations. Workforce needs will in part include understanding current industry concerns, personnel competencies, current and future skills, growth rates, geographical distributions, certifications, and sources of pre-service and in-service personnel. Dave Rosage of the NASA Goddard Space Flight Center and a panel of MAPPS members will lead a discussion to help NASA specifically address private firms' near and long-term personnel needs to be included in NASA's Remote Sensing Professional Development Program. In addition, Dave Rosage will present perspectives on how remote sensing technologies are evolving, new NASA instruments being developed, and what future workforce skills are expected to support these new developments.

  16. eGY-Africa: Addressing the Digital Divide for Science in Africa

    SciTech Connect

    Barton, C. E.

    2010-05-25

    Adoption of information and communication technologies and access to the Internet is expanding in Africa, but because of the rapid growth elsewhere, a Digital Divide between Africa and the rest of the world exists, and the gap is growing. In many sub-Saharan African countries, education and research sector suffer some of the worst deficiencies in access to the Internet, despite progress in development of NRENs National Research and Education (cyber) Networks. By contrast, it is widely acknowledged in policy statements from the African Union, the UN, and others that strength in this very sector provides the key to meeting and sustaining Millennium Development Goals. Developed countries with effective cyber-capabilities proclaim the benefits to rich and poor alike arising from the Information Revolution. This is but a dream for many scientists in African institutions. As the world of science becomes increasingly Internet-dependent, so they become increasingly isolated. eGY-Africa is a bottom-up initiative by African scientists and their collaborators to try to reduce this Digital Divide by a campaign of advocacy for better institutional facilities. Four approaches are being taken. The present status of Internet services, problems, and plans are being mapped via a combination of direct measurement of Internet performance (the PingER Project) and a questionnaire-based survey. Information is being gathered on policy statements and initiatives aimed at reducing the Digital Divide, which can be used for arguing the case for better Internet facilities. Groups of concerned scientists are being formed at the national, regional levels in Africa, building on existing networks as much as possible. Opinion in the international science community is being mobilized. Finally, and perhaps most important of all, eGY-Africa is seeking to engage with the many other programs, initiatives, and bodies that share the goal of reducing the Digital Divide either as a direct policy objective

  17. eGY-Africa: Addressing the Digital Divide for Science in Africa

    SciTech Connect

    Barton, C.E.; Amory-Mazaudier, C.; Barry, B.; Chukwuma; Cottrell, R.L.; Kalim, U.; Mebrahtu, A.; Petitdidier, M.; Rabiu, B.; Reeves, C.; /Earthworks bv, Delft

    2010-06-16

    Adoption of information and communication technologies and access to the Internet is expanding in Africa, but because of the rapid growth elsewhere, a Digital Divide between Africa and the rest of the world exists, and the gap is growing. In many sub-Saharan African countries, education and research sector suffers some of the worst deficiencies in access to the Internet, despite progress in development of NRENs - National Research and Education (cyber) Networks. By contrast, it is widely acknowledged in policy statements from the African Union, the UN, and others that strength in this very sector provides the key to meeting and sustaining Millennium Development Goals. Developed countries with effective cyber-capabilities proclaim the benefits to rich and poor alike arising from the Information Revolution. This is but a dream for many scientists in African institutions. As the world of science becomes increasingly Internet-dependent, so they become increasingly isolated. eGY-Africa is a bottom-up initiative by African scientists and their collaborators to try to reduce this Digital Divide by a campaign of advocacy for better institutional facilities. Four approaches are being taken. The present status of Internet services, problems, and plans are being mapped via a combination of direct measurement of Internet performance (the PingER Project) and a questionnaire-based survey. Information is being gathered on policy statements and initiatives aimed at reducing the Digital Divide, which can be used for arguing the case for better Internet facilities. Groups of concerned scientists are being formed at the national, regional levels in Africa, building on existing networks as much as possible. Opinion in the international science community is being mobilized. Finally, and perhaps most important of all, eGY-Africa is seeking to engage with the many other programs, initiatives, and bodies that share the goal of reducing the Digital Divide - either as a direct policy

  18. eGY-Africa: addressing the digital divide for science in Africa

    NASA Astrophysics Data System (ADS)

    Baki, Paul; Nguno, Anna; Barton, Charles; Amaeshi, Larry; Tenthani, Chifundo; Petitdidier, Monique; Cottrell, Les

    2013-04-01

    Adoption of information and communication technologies and access to the Internet is expanding in Africa, but because of the rapid growth elsewhere, a Digital Divide between Africa and the rest of the world exists. In many sub-Saharan African countries, education and research sector suffers some of the worst deficiencies in access to the Internet, despite progress in the development of NRENs - National Research and Education (cyber) Networks. By contrast, it is widely acknowledged in policy statements from the African Union, the UN, and others that strength in this very sector provides the key to meeting and sustaining Millennium Development Goals. Developed countries with effective cyber-capabilities proclaim the benefits to rich and poor alike arising from the Information Revolution. This is still a dream for many scientists in African institutions. As the world of science becomes increasingly Internet-dependent, so they become increasingly isolated. eGY-Africa is a bottom-up initiative by African scientists and their collaborators to try to reduce this digital divide by a campaign of advocacy for better institutional facilities. Four approaches are being taken. The present status of Internet services, problems, and plans are being mapped via a combination of direct measurement of Internet performance (the PingER Project) and a questionnaire-based survey. Information is being gathered on policy statements and initiatives aimed at reducing the digital divide, which can be used for arguing the case for better Internet facilities. Groups of concerned scientists are being formed at the national, regional levels in Africa, building on existing networks as much as possible. Opinion in the international science community is being mobilized. Finally, and perhaps most important of all, eGY-Africa is seeking to engage with the many other programs, initiatives, and bodies that share the goal of reducing the digital divide - either as a direct policy objective, or indirectly

  19. Prevention of preterm birth: harnessing science to address the global epidemic.

    PubMed

    Rubens, Craig E; Sadovsky, Yoel; Muglia, Louis; Gravett, Michael G; Lackritz, Eve; Gravett, Courtney

    2014-11-12

    Preterm birth is a leading cause of infant morbidity and mortality worldwide, but current interventions to prevent prematurity are largely ineffective. Preterm birth is increasingly recognized as an outcome that can result from a variety of pathological processes. Despite current research efforts, the mechanisms underlying these processes remain poorly understood and are influenced by a range of biological and environmental factors. Research with modern techniques is needed to understand the mechanisms responsible for preterm labor and birth and identify targets for diagnostic and therapeutic solutions. This review evaluates the state of reproductive science relevant to understanding the causes of preterm birth, identifies potential targets for prevention, and outlines challenges and opportunities for translating research findings into effective interventions.

  20. Identifying and Addressing Stakeholder Interests in Design Science Research: An Analysis Using Critical Systems Heuristics

    NASA Astrophysics Data System (ADS)

    Venable, John R.

    This paper utilises the Critical Systems Heuristics (CSH) framework developed by Werner Ulrich to critically consider the stakeholders and design goals that should be considered as relevant by researchers conducing Design Science Research (DSR). CSH provides a philosophically and theoretically grounded framework and means for critical consideration of the choices of stakeholders considered to be relevant to any system under design consideration. The paper recommends that legitimately undertaken DSR should include witnesses to represent the interests of the future consumers of the outcomes of DSR, i.e., the future clients, decision makers, professionals, and other non-included stakeholders in the future use of the solution technologies to be invented in DSR. The paper further discusses options for how witnesses might be included, who should be witnessed for and obstacles to implementing the recommendations.

  1. New and improved proteomics technologies for understanding complex biological systems: Addressing a grand challenge in the life sciences

    PubMed Central

    Hood, Leroy E.; Omenn, Gilbert S.; Moritz, Robert L.; Aebersold, Ruedi; Yamamoto, Keith R.; Amos, Michael; Hunter-Cevera, Jennie; Locascio, Laurie

    2014-01-01

    This White Paper sets out a Life Sciences Grand Challenge for Proteomics Technologies to enhance our understanding of complex biological systems, link genomes with phenotypes, and bring broad benefits to the biosciences and the US economy. The paper is based on a workshop hosted by the National Institute of Standards and Technology (NIST) in Gaithersburg, MD, 14–15 February 2011, with participants from many federal R&D agencies and research communities, under the aegis of the US National Science and Technology Council (NSTC). Opportunities are identified for a coordinated R&D effort to achieve major technology-based goals and address societal challenges in health, agriculture, nutrition, energy, environment, national security, and economic development. PMID:22807061

  2. New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.

    PubMed

    Hood, Leroy E; Omenn, Gilbert S; Moritz, Robert L; Aebersold, Ruedi; Yamamoto, Keith R; Amos, Michael; Hunter-Cevera, Jennie; Locascio, Laurie

    2012-09-01

    This White Paper sets out a Life Sciences Grand Challenge for Proteomics Technologies to enhance our understanding of complex biological systems, link genomes with phenotypes, and bring broad benefits to the biosciences and the US economy. The paper is based on a workshop hosted by the National Institute of Standards and Technology (NIST) in Gaithersburg, MD, 14-15 February 2011, with participants from many federal R&D agencies and research communities, under the aegis of the US National Science and Technology Council (NSTC). Opportunities are identified for a coordinated R&D effort to achieve major technology-based goals and address societal challenges in health, agriculture, nutrition, energy, environment, national security, and economic development.

  3. Holography And The Freedom Of Science - A Welcome Address To ICHA '86

    NASA Astrophysics Data System (ADS)

    von Bally, Gert

    1988-01-01

    It was a great honour for me to assist in preparing this International Conference on Holographic Applications for that part of the world where the idea of holography was created by Dennis Gabor in the fourties - that is Europe. Although my function as a chairman of the regional European program committee was combined with some additional work, it was always a pleasure for me to contribute to an effort to bring us "holographers" together in a country most of us, who are foreign here, have not yet been before, and in this way spreading the exchange of experience and knowledge to our mutual advantage also in this part of the world. As scientists we have the great chance to overcome borders and restrictions of ideology and other constraints, and to meet openly and with friendship. The name of the place in Beijing where ICHA-86 was hold - Friendship Hotel - may act as a symbol in this sense. But on the other hand this puts a burden on our shoulders, that is to work on keeping this independance and freedom of science. If we look on our scientific child or - for the younger ones among us - already our scientific mother - I mean holography, we cannot avoid recognizing that we did not only always use ways to keep this independance and freedom. I mean the deep envolvement of holographic technolgies in the - to my feelings - darkest point of human thinking - that is the development of mutual military deterrence, which threatens mankind and separates people, including ourselves. We have to confess that this is true from the very beginning of practical applications of holography. Who takes the time to read not only the scientific text of publications in our field but also pays attention to where and what for these investigations were undertaken and by whom they were paid, can easily see that this is still an increasingly growing development. Also in this meeting, if we want to or not, we have to realize that the ambiguity of applications of the most modern developments in our

  4. Addressing Grand Challenges in Earth Observation Science: The Earth Observation Data Centre for Water Resources Monitoring

    NASA Astrophysics Data System (ADS)

    Wagner, W.; Fröhlich, J.; Wotawa, G.; Stowasser, R.; Staudinger, M.; Hoffmann, C.; Walli, A.; Federspiel, C.; Aspetsberger, M.; Atzberger, C.; Briese, C.; Notarnicola, C.; Zebisch, M.; Boresch, A.; Enenkel, M.; Kidd, R.; von Beringe, A.; Hasenauer, S.; Naeimi, V.; Mücke, W.

    2014-09-01

    Earth observation is entering a new era where the increasing availability of free and open global satellite data sets combined with the computing power offered by modern information technologies opens up the possibility to process high-resolution data sets at global scale and short repeat intervals in a fully automatic fashion. This will not only boost the availability of higher level earth observation data in purely quantitative terms, but can also be expected to trigger a step change in the quality and usability of earth observation data. However, the technical, scientific, and organisational challenges that need to be overcome to arrive at this point are significant. First of all, Petabyte-scale data centres are needed for storing and processing complete satellite data records. Second, innovative processing chains that allow fully automatic processing of the satellite data from the raw sensor records to higher-level geophysical products need to be developed. Last but not least, new models of cooperation between public and private actors need to be found in order to live up to the first two challenges. This paper offers a discussion of how the Earth Observation Data Centre for Water Resources Monitoring (EODC) - a catalyser for an open and international cooperation of public and private organisations - will address these three grand challenges with the aim to foster the use of earth observation for monitoring of global water resources.

  5. Teaching lesbian, gay, bisexual and transgender health in a South African health sciences faculty: addressing the gap

    PubMed Central

    2013-01-01

    Background People who identity as lesbian, gay, bisexual and transgender (LGBT) have specific health needs. Sexual orientation and gender identity are social determinants of health, as homophobia and heteronormativity persist as prejudices in society. LGBT patients often experience discrimination and prejudice in health care settings. While recent South African policies recognise the need for providing LGBT specific health care, no curricula for teaching about LGBT health related issues exist in South African health sciences faculties. This study aimed to determine the extent to which LGBT health related content is taught in the University of Cape Town’s medical curriculum. Methods A curriculum mapping exercise was conducted through an online survey of all academic staff at the UCT health sciences faculty, determining LGBT health related content, pedagogical methodology and assessment. Results 127 academics, across 31 divisions and research units in the Faculty of Health Sciences, responded to the survey, of which 93 completed the questionnaire. Ten taught some content related to LGBT health in the MBChB curriculum. No LGBT health related content was taught in the allied health sciences curricula. The MBChB curriculum provided no opportunity for students to challenge their own attitudes towards LGBT patients, and key LGBT health topics such as safer sex, mental health, substance abuse and adolescent health were not addressed. Conclusion At present, UCTs health sciences curricula do not adequately address LGBT specific health issues. Where LGBT health related content is taught in the MBChB curriculum, it is largely discretionary, unsystematic and not incorporated into the overarching structure. Coordinated initiatives to integrate LGBT health related content into all health sciences curricula should be supported, and follow an approach that challenges students to develop professional attitudes and behaviour concerning care for patients from LGBT backgrounds, as

  6. eGY-Africa: addressing the digital divide for science in Africa

    NASA Astrophysics Data System (ADS)

    Barton, C.; Petitdidier, M.; Cottrell, L.; Fox, P.

    2009-04-01

    The digital divide is worse in Africa than in the rest of the world, the gap is growing, and in many sub-Saharan African countries the education and research sector suffers some of the worst deficiencies in access to the Internet. By contrast, it is widely acknowledged in policy statements from the African Union, the UN, and others that this very sector provides the key to meeting and sustaining Millenium Development Goals. Developed countries with effective cyber-capabilities wax eloquent about the equal benefits to rich and poor alike arising from the Information Revolution. This is but a dream for many (most?) scientists in African institutions; as the world of science becomes increasingly Internet-dependent, so they become increasingly isolated. eGY-Africa is a bottom-up initiative by African scientists and their collaborators to try to reduce this digital divide by a campaign of advocacy for better institutional facilities. The present status of Internet services, problems, and plans are being mapped via a combination of a survey questionnaire-based survey and direct measurement of Internet performance (the PingER Project). Information is being gathered on policy statements and initiatives aimed at reducing the Digital Divide. eGY-Africa is establishing National groups of concerned scientists and engaging with those initiatives with related goals. The expectation is that informed opinion from the scientific community at the institutional, national, and international levels can be used to influence the decision makers and donors who are in a position to deliver better capabilities.

  7. Educating for the 21st-Century Health Care System: An Interdependent Framework of Basic, Clinical, and Systems Sciences.

    PubMed

    Gonzalo, Jed D; Haidet, Paul; Papp, Klara K; Wolpaw, Daniel R; Moser, Eileen; Wittenstein, Robin D; Wolpaw, Terry

    2017-01-01

    In the face of a fragmented and poorly performing health care delivery system, medical education in the United States is poised for disruption. Despite broad-based recommendations to better align physician training with societal needs, adaptive change has been slow. Traditionally, medical education has focused on the basic and clinical sciences, largely removed from the newer systems sciences such as population health, policy, financing, health care delivery, and teamwork. In this article, authors examine the current state of medical education with respect to systems sciences and propose a new framework for educating physicians in adapting to and practicing in systems-based environments. Specifically, the authors propose an educational shift from a two-pillar framework to a three-pillar framework where basic, clinical, and systems sciences are interdependent. In this new three-pillar framework, students not only learn the interconnectivity in the basic, clinical, and systems sciences but also uncover relevance and meaning in their education through authentic, value-added, and patient-centered roles as navigators within the health care system. Authors describe the Systems Navigation Curriculum, currently implemented for all students at the Penn State College of Medicine, as an example of this three-pillar educational model. Simple adjustments, such as including occasional systems topics in medical curriculum, will not foster graduates prepared to practice in the 21st-century health care system. Adequate preparation requires an explicit focus on the systems sciences as a vital and equal component of physician education.

  8. In-situ Subsurface Science Addressed By The "mole" On The Beagle 2 Mars Lander

    NASA Astrophysics Data System (ADS)

    Richter, L.; Gromov, V. V.; Möhlmann, D.; Kochan, H.; Tokano, T.

    The payload of the Beagle 2 lander of ESA's Mars Express mission includes a regolith- penetrating, tethered "Mole" intended for acquisition of several subsurface soil sam- ples from depths between about 30 cm and some 1E1.5 m. These samples will then be analysed by the Gas Analysis Package instrument on the lander, primarily with re- gard to isotopic composition and to organic molecules. However, after giving a brief overview of the Mole experiment, this paper focuses on additional in-situ science con- ducted by the Beagle 2 Mole system, also referred to as the PLanetary Underground TOol (PLUTO): while it penetrates into the Martian regolith by way of soil displace- ment through the action of an internal hammering mechanism, the Mole will allow mechanical properties of the regolith to be studied as a function of depth - being a first on a Mars mission - and additionally, a temperature sensor mounted on the outside of the Mole will support investigations of soil thermophysical properties and measure- ments of the subsurface temperature profile, again as a first-time achievement. Using a Mole soil penetration theory calibrated by ground-based experiments, regolith bulk density, cohesion, and internal friction angle can be constrained as a function of depth using the Mole penetration path (and retrieval path) vs. time which is measured by a winch rotation sensor indicating the amount of tether extracted by the Mole. The obtained depth profiles of these quantities should provide insight into the depositional history and stratigraphy of the regolith at the site. Measurements of the regolith tem- perature will be conducted by the Mole both as a function of depth during soil in- trusion, and as a function of time for constant depth, as the Mole can be left in the subsurface for periods of days or weeks before it is retrieved, especially during the later part of the Beagle 2 landed mission. Subsurface temperature measurements will support calibrations of Mars regolith

  9. In-situ subsurface science addressed by the Mole on the Beagle 2 Mars lander

    NASA Astrophysics Data System (ADS)

    Richter, L.; Gromov, V.; Kochan, H.; Möhlmann, D.; Tokano, T.

    The payload of the Beagle 2 lander of ESA's Mars Express mission includes a regolithpenetrating, tethered "Mole" intended for acquisition of several subsurface soil sam ples from depths between about 30 cm and some 1E1.5 m. These samples will then be analysed by the Gas Analysis Package instrument on the lander, primarily with regard to isotopic composition and to organic molecules. However, after giving a brief overview of the Mole experiment, this paper focuses on additional in-situ science conducted by the Beagle 2 Mole system, also referred to as the PLanetary Underground TOol (PLUTO): while it penetrates into the Martian regolith by way of soil displacement through the action of an internal hammering mechanism, the Mole will allow mechanical properties of the regolith to be studied as a function of depth - being a first on a Mars mission - and additionally, a temperature sensor mounted on the outside of the Mole will support investigations of soil thermophysical properties and measurements of the subsurface temperature profile, again as a first-time achievement. Using a Mole soil penetration theory calibrated by ground-based experiments, regolith bulk density, cohesion, and internal friction angle can be constrained as a function of depth using the Mole penetration path (and retrieval path) vs. time which is measured by a winch rotation sensor indicating the amount of tether extracted by the Mole. The obtained depth profiles of these quantities should provide insight into the depositional history and stratigraphy of the regolith at the site. Measurements of the regolith temperature will be conducted by the Mole both as a function of depth during soil intrusion, and as a function of time for constant depth, as the Mole can be left in the subsurface for periods of days or weeks before it is retrieved, especially during the later part of the Beagle 2 landed mission. Subsurface temperature measurements will support calibrations of Mars regolith thermophysical

  10. Concerns of early career agricultural science teachers and the perceived effectiveness of educator preparation programs in addressing those concerns

    NASA Astrophysics Data System (ADS)

    Pearson, Camilla E.

    Little is known about the concerns and needs of early career agricultural teachers associated with the various routes to certification and how these routes address those concerns. The purpose of this study is to determine how selected early career agriculture teachers perceive their teacher preparation program and how effective their programs were at addressing these concerns during their first year of teaching. The sample consisted of secondary agricultural teachers in Texas FFA Areas V and VI, who self-identified themselves as an early career agricultural teacher in their first 3 years of teaching. The first phase included a web-based survey administered to assess the concerns of early career agricultural teachers. Two Likert-type scales were used, and these were used to assess the perceived importance of problems faced by early career agricultural teachers and the frequency in which they encounter those problems. The second phase included a qualitative interview to better understand the perceived relationship between participants' undergraduate preparation, experiences in agriculture and related organizations, and other related activities in preparing them as agriculture science teachers. The teachers interviewed in this study indicated that overall, they were pleased with their preparation. Teacher educators from both programs should address the concerns presented from all teachers to further prepare them for issues faced by early career teachers because it is evident that these issues are not going away.

  11. The Effectiveness of an Educational Game for Teaching Optometry Students Basic and Applied Science

    PubMed Central

    Trevino, Richard; Majcher, Carolyn; Rabin, Jeff; Kent, Theresa; Maki, Yutaka; Wingert, Timothy

    2016-01-01

    Purpose To compare the effectiveness of an educational board game with interactive didactic instruction for teaching optometry students elements of the core optometric curriculum. Methods Forty-two optometry students were divided into two GPA-matched groups and assigned to either 12 hours of game play (game group) or 12 hours of interactive didactic instruction (lecture group). The same material from the core optometric curriculum was delivered to both groups. Game play was accomplished via an original board game. Written examinations assessed change in knowledge level. A post-intervention opinion survey assessed student attitudes. Results There was no significant difference in pre- or post-intervention test scores between the lecture and game groups (Pre-test: p = 0.9; Post-test: p = 0.5). Post-intervention test scores increased significantly from baseline (Game group: 29.3% gain, Didactic group: 31.5% gain; p<0.001 for each). The score increase difference between groups was not statistically significant (p = 0.6). The post-intervention attitude survey did not reveal any significant between group differences (p = 0.5). Conclusions Our results indicate that an educational game and interactive didactic instruction can be equally effective in teaching optometry students basic and applied science. Furthermore, both modes of instruction have the potential to be equally engaging and enjoyable experiences. PMID:27233041

  12. Arthroscopic contact Nd:YAG laser meniscectomy: basic science, surgical technique, and clinical follow up

    NASA Astrophysics Data System (ADS)

    O'Brien, Stephen J.; Fealy, Stephen V.; Gibney, Mary A.; Miller, Drew V.; Kelly, Anne M.

    1990-06-01

    Recent basic science studies (5) have provided a scientific foundation for the use of the Contact Nd:YAG Laser as an arthroscopic tool for xneniscal resection and acroxnioplasty of the shoulder in a saline medium. This study prospectively evaluates the results of a three stage laboratory investigation as well as the clinical results of arthroscopic xneniscal resection. Fifteen patients with meniscal tears underwent subtotal meniscectomies utilizing a Contact Nd:YAG Laser (Surgical Laser Technologies; Malvern, Pennsylvania) . This was done in a saline medium with an average laser wattage of 25 W, (range 20 W to 30 W). Patients were evaluated postoperatively with reference to subjective and objective parameters at one week and four weeks postoperatively. Patients were evaluated with regard to wound healing, intraarticular swelling and pain. Assessment of technical parameters such as ease of resection, time of resection and instrument access were compared to conventional instruments. All fifteen patients were rated as having clinically excellent results based on pain relief, wound healing and swelling. In addition, although there was increased time with setting up the laser and calibrating it, there was not an increase in time for meniscal resection. Little, or no, secondary "trimmuning" was necessary with the laser. Increased accessibility was noted due to the small size of the laser. Arthroscopic Contact Nd:YAG Laser surgery is a safe and effective tool for menisca]. resection and coagulation in arthroscopic acromioplasties. It provides significant advantages over conventional cutting instruments with regard to accessibility and reduced need for secondary instruments.

  13. Physiology education in North American dental schools: the basic science survey series.

    PubMed

    Gautam, Medha; Shaw, David H; Pate, Ted D; Lambert, H Wayne

    2014-06-01

    As part of the Basic Science Survey Series for Dentistry, members of the American Dental Education Association (ADEA) Physiology, Pharmacology, and Therapeutics Section surveyed directors of physiology courses in North American dental schools. The survey was designed to assess, among other things, faculty affiliation and experience of course directors, teaching methods, general course content and emphasis, extent of interdisciplinary (shared) instruction, and impact of recent curricular changes. Responses were received from forty-four of sixty-seven (65.7 percent) U.S. and Canadian dental schools. The findings suggest the following: substantial variation exists in instructional hours, faculty affiliation, class size, and interdisciplinary nature of physiology courses; physiology course content emphasis is similar between schools; student contact hours in physiology, which have remained relatively stable in the past fifteen years, are starting to be reduced; recent curricular changes have often been directed towards enhancing the integrative and clinically relevant aspects of physiology instruction; and a trend toward innovative content delivery, such as use of computer-assisted instruction, is evident. Data from this study may be useful to physiology course directors, curriculum committees, and other dental educators with an interest in integrative and interprofessional education.

  14. Expanding the basic science debate: the role of physics knowledge in interpreting clinical findings.

    PubMed

    Goldszmidt, Mark; Minda, John Paul; Devantier, Sarah L; Skye, Aimee L; Woods, Nicole N

    2012-10-01

    Current research suggests a role for biomedical knowledge in learning and retaining concepts related to medical diagnosis. However, learning may be influenced by other, non-biomedical knowledge. We explored this idea using an experimental design and examined the effects of causal knowledge on the learning, retention, and interpretation of medical information. Participants studied a handout about several respiratory disorders and how to interpret respiratory exam findings. The control group received the information in standard "textbook" format and the experimental group was presented with the same information as well as a causal explanation about how sound travels through lungs in both the normal and disease states. Comprehension and memory of the information was evaluated with a multiple-choice exam. Several questions that were not related to the causal knowledge served as control items. Questions related to the interpretation of physical exam findings served as the critical test items. The experimental group outperformed the control group on the critical test items, and our study shows that a causal explanation can improve a student's memory for interpreting clinical details. We suggest an expansion of which basic sciences are considered fundamental to medical education.

  15. Role of MR imaging in sports medicine research. Basic science and clinical research studies.

    PubMed

    Rodkey, W G; Steadman, J R; Ho, C P

    1999-02-01

    The advent and advancement of MR imaging have provided an entire new dimension for medical imaging. MR imaging has been especially useful because of its capacity to image nonmineralized tissues with a very high degree of resolution. Although modalities such as ultrasound and scintigraphy have proven useful for specific purposes, it is MR imaging that has the most utility and capabilities, especially in the area of sports-induced injuries. The technology associated with MR imaging has expanded greatly, and it continues to evolve at a rapid pace. The result has been an ever-increasing diagnostic capability that has become more economic with time. As described previously, MR imaging is gaining importance in the area of comparative medicine for animal athletes as well. It is also interesting to note that MR imaging now has a greater potential for monitoring physiological and biochemical changes as well as anatomic ones. Some newer MR units actually include physiologic data acquisition components. Consequently, new bioassays and nondestructive tissue tests can be performed to further understand the molecular biology and ongoing cellular processes in any given condition. Coupled with MR spectroscopy, the enhanced MR techniques should continue to contribute to the overall information that will be integrated into the training and rehabilitation of patients with sports-induced inflammation and injuries. The authors support and encourage ongoing efforts in the area of MR imaging research, both basic science and clinical studies.

  16. Developmental defects of enamel and dentine: challenges for basic science research and clinical management.

    PubMed

    Seow, W K

    2014-06-01

    Abnormalities of enamel and dentine are caused by a variety of interacting factors ranging from genetic defects to environmental insults. The genetic changes associated with some types of enamel and dentine defects have been mapped, and many environmental influences, including medical illnesses that can damage enamel and dentine have been identified. Developmental enamel defects may present as enamel hypoplasia or hypomineralization while dentine defects frequently demonstrate aberrant calcifications and abnormalities of the dentine-pulp complex. Clinically, developmental enamel defects often present with problems of discolouration and aesthetics, tooth sensitivity, and susceptibility to caries, wear and erosion. In contrast, dentine defects are a risk for endodontic complications resulting from dentine hypomineralization and pulpal abnormalities. The main goals of managing developmental abnormalities of enamel and dentine are early diagnosis and improvement of appearance and function by preserving the dentition and preventing complications. However, despite major advances in scientific knowledge regarding the causes of enamel and dentine defects, further research is required in order to translate the knowledge gained in the basic sciences research to accurate clinical diagnosis and successful treatment of the defects.

  17. Care for child development: basic science rationale and effects of interventions.

    PubMed

    Holt, Rebecca L; Mikati, Mohamad A

    2011-04-01

    The past few years have witnessed increasing interest in devising programs to enhance early childhood development. We review current understandings of brain development, recent advances in this field, and their implications for clinical interventions. An expanding body of basic science laboratory data demonstrates that several interventions, including environmental enrichment, level of parental interaction, erythropoietin, antidepressants, transcranial magnetic stimulation, transcranial direct current stimulation, hypothermia, nutritional supplements, and stem cells, can enhance cerebral plasticity. Emerging clinical data, using functional magnetic resonance imaging and clinical evaluations, also support the hypothesis that clinical interventions can increase the developmental potential of children, rather than merely allowing the child to achieve an already predetermined potential. Such interventions include early developmental enrichment programs, which have improved cognitive function; high-energy and high-protein diets, which have increased brain growth in infants with perinatal brain damage; constraint-induced movement therapy, which has improved motor function in patients with stroke, cerebral palsy, and cerebral hemispherectomy; and transcranial magnetic stimulation, which has improved motor function in stroke patients.

  18. Pharmacologic treatment of inner ear: from basic science to the patient.

    PubMed

    Lefebvre, P P; Staecker, H; Van de Water, T; Moonen, G; Malgrange, B

    2002-01-01

    Most of the deafness are of sensorineural origin and are characterized by a loss of hair cells and of spiral ganglion neurons. At the present time, hearing aids are the only treatment. However, in some diseases of the inner ear, pharmacological treatment have been proposed and used successfully. In this paper, we will review some basic science aspects of the biology of the neurosensory structures of the inner ear, in particular of the auditory neurons, that lead to the rationale of some treatments for the inner ear diseases. Developmental studies, neuronal cell culture experiments, and analyses of gene knockout animals reveal a number of growth factors which are important for the rescue and repair of injured auditory neurons in the inner ear. These factors rescue the injured auditory neurons in vivo. Furthermore, perfusion of antioxydant to the cochlea prevented the hearing loss induced by cisplatin. These in vitro and in vivo experiments demonstrate that it is possible to manipulate the neurosensory structures of the inner ear and provide an effective treatment to prevent the degeneration of the neurons. The molecules or drugs can be administered locally to the inner ear through a direct perilymphatic perfusion or through the round window membrane. As an example, we will discuss the treatment of patients suffering from idiopathic sensorineural hearing loss which can be treated successfully by a perfusion through the round window membrane, improving their hearing threshold and their speech discrimination.

  19. Exploration of an E-Learning Model to Foster Critical Thinking on Basic Science Concepts during Work Placements

    ERIC Educational Resources Information Center

    de Leng, Bas A.; Dolmans, Diana H. J. M.; Jobsis, Rijn; Muijtjens, Arno M. M.; van der Vleuten, Cees P. M.

    2009-01-01

    We designed an e-learning model to promote critical thinking about basic science topics in online communities of students during work placements in higher education. To determine the effectiveness and efficiency of the model we explored the online discussions in two case studies. We evaluated the quantity of the interactions by looking at…

  20. The Use of Self-Learning Modules to Facilitate Learning of Basic Science Concepts in an Integrated Medical Curriculum

    ERIC Educational Resources Information Center

    Khalil, Mohammed K.; Nelson, Loren D.; Kibble, Jonathan D.

    2010-01-01

    This study used qualitative and quantitative approaches to evaluate the effectiveness of self-learning modules (SLMs) developed to facilitate and individualize students' learning of basic medical sciences. Twenty physiology and nineteen microanatomy SLMs were designed with interactive images, animations, narrations, and self-assessments. Of 41…

  1. The Unexpected Evolution of Basic Science Studies about Cyclic Nucleotide Action into a Treatment for Erectile Dysfunction

    PubMed Central

    Corbin, Jackie

    2015-01-01

    In these Reflections, I describe my perceived role in discoveries made in the cyclic nucleotide field that culminated in the advent of PDE5 inhibitors that treat erectile dysfunction, such as Viagra, Levitra, and Cialis. The discoveries emphasize the critical role of basic science, which often evolves in unpredictable and circuitous paths, in improving human health. PMID:25505249

  2. Dealing with the Problem of Bridging the Gap Between the Basic Sciences and Clinical Practice: Teaching, Research and Service.

    ERIC Educational Resources Information Center

    Remington, Richard D.

    1980-01-01

    Conflicts between basic research and applied science segments of pharmacy are discussed, with special attention to traditional goals of teaching, research, and service and to improving relationships between these branches of the profession. Techniques already tried, such as peer review of grant proposals, and faculty nontenure "service track," are…

  3. Key steps for integrating a basic science throughout a medical school curriculum using an e-learning approach.

    PubMed

    Dubois, Eline Agnès; Franson, Kari Lanette

    2009-09-01

    Basic sciences can be integrated into the medical school curriculum via e-learning. The process of integrating a basic science in this manner resembles a curricular change. The change usually begins with an idea for using e-learning to teach a basic science and establishing the need for the innovation. In the planning phase, learning outcomes are formulated and a prototype of the program is developed based on the desired requirements. A realistic concept is formed after considering the limitations of the current institute. Next, a project team is assembled to develop the program and plan its integration. Incorporation of the e-learning program is facilitated by a well-developed and communicated integration plan. Various course coordinators are contacted to determine content of the e-learning program as well as establish assessment. Linking the e-learning program to existing course activities and thereby applying the basic science into the clinical context enhances the degree of integration. The success of the integration is demonstrated by a positive assessment of the program including favourable cost-benefit analysis and improved student performance. Lastly, when the program becomes institutionalised, continuously updating content and technology (when appropriate), and evaluating the integration contribute to the prolonged survival of the e-learning program.

  4. The Articulation of Integration of Clinical and Basic Sciences in Concept Maps: Differences between Experienced and Resident Groups

    ERIC Educational Resources Information Center

    Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan

    2016-01-01

    To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic…

  5. Changes in Study Strategies of Medical Students between Basic Science Courses and Clerkships Are Associated with Performance

    ERIC Educational Resources Information Center

    Ensminger, David C.; Hoyt, Amy E.; Chandrasekhar, Arcot J.; McNulty, John A.

    2013-01-01

    We tested the hypothesis that medical students change their study strategies when transitioning from basic science courses to clerkships, and that their study practices are associated with performance scores. Factor scores for three approaches to studying (construction, rote, and review) generated from student (n = 150) responses to a…

  6. Coherent Teaching and Need-Based Learning in Science: An Approach to Teach Engineering Students in Basic Physics Courses

    ERIC Educational Resources Information Center

    Kurki-Suonio, T.; Hakola, A.

    2007-01-01

    In the present paper, we propose an alternative, based on constructivism, to the conventional way of teaching basic physics courses at the university level. We call this approach "coherent teaching" and the underlying philosophy of teaching science and engineering "need-based learning". We have been applying this philosophy in…

  7. Investigation of Pre-Service Teachers' Opinions about Science in Terms of the Basic Elements of the Education Program

    ERIC Educational Resources Information Center

    Sengul, Ozge Aydin

    2016-01-01

    The purpose of the current study is to investigate the pre-service teachers' opinions about science within the context of the basic elements of the education program, such as objectives, content, learning-teaching process and evaluation. The study was designed as a case study, one of the qualitative research methods. The participants of the study…

  8. Thinking science with thinking machines: The multiple realities of basic and applied knowledge in a research border zone.

    PubMed

    Hoffman, Steve G

    2015-04-01

    Some scholars dismiss the distinction between basic and applied science as passé, yet substantive assumptions about this boundary remain obdurate in research policy, popular rhetoric, the sociology and philosophy of science, and, indeed, at the level of bench practice. In this article, I draw on a multiple ontology framework to provide a more stable affirmation of a constructivist position in science and technology studies that cannot be reduced to a matter of competing perspectives on a single reality. The analysis is grounded in ethnographic research in the border zone of Artificial Intelligence science. I translate in-situ moments in which members of neighboring but differently situated labs engage in three distinct repertoires that render the reality of basic and applied science: partitioning, flipping, and collapsing. While the essences of scientific objects are nowhere to be found, the boundary between basic and applied is neither illusion nor mere propaganda. Instead, distinctions among scientific knowledge are made real as a matter of course.

  9. Integrated case studies and medical decision making: a novel, computer-assisted bridge from the basic sciences to the clinics.

    PubMed

    Schor, N F; Troen, P; Adler, S; Williams, J G; Kanter, S L; Mahling, D E; Sorrows, B; Skogseid, I; Bernier, G M

    1995-09-01

    This article describes a novel course that was designed to bridge the gap between the basic science years and clinical experiences in medical school by using information science and computer technology as major components of problem-based learning (PBL) sessions. The course, Integrated Case Studies and Medical Decision Making, was first given to second-year students at the University of Pittsburgh School of Medicine in the spring of 1994. It consists of 13 PBL exercises, each of which explores a clinical case. The cases, including images and gated access to information, are housed on a computer. Using one of 16 networked terminals in specially designed small-group rooms, groups of nine students progress through the cases with a faculty facilitator. The responses of students and faculty to the initial year of the course were favorable. In comparison with traditional PBL sessions, enhanced quality of and access to images and accountability for accessing case information in sequential fashion were cited as major strengths of the course. Juxtaposition of basic science and clinical material and utility in reviewing for the United States Medical Licensing Examination were also cited as strengths. The diversity of the basic science material involved in completing the cases drew overwhelming enthusiasm from students and facilitators alike. In conclusion, the course successfully employs computer and information science technology, which will be of increasing importance to future physicians. The course also serves as an effective bridge to the clinical years of medical school and as a study adjunct for the USMLE.

  10. NASA GSFC Science Communication Working Group: Addressing Barriers to Scientist and Engineer Participation in Education and Public Outreach Activities

    NASA Astrophysics Data System (ADS)

    Bleacher, L.; Hsu, B. C.; Campbell, B. A.; Hess, M.

    2011-12-01

    The Science Communication Working Group (SCWG) at NASA Goddard Space Flight Center (GSFC) has been in existence since late 2007. The SCWG is comprised of education and public outreach (E/PO) professionals, public affairs specialists, scientists, and engineers. The goals of the SCWG are to identify barriers to scientist and engineer engagement in E/PO activities and to enable those scientists and engineers who wish to contribute to E/PO to be able to do so. SCWG members have held meetings with scientists and engineers across GSFC to determine barriers to their involvement in E/PO. During these meetings, SCWG members presented examples of successful, ongoing E/PO projects, encouraged active research scientists and engineers to talk about their own E/PO efforts and what worked for them, discussed the E/PO working environment, discussed opportunities for getting involved in E/PO (particularly in high-impact efforts that do not take much time), handed out booklets on effective E/PO, and asked scientists and engineers what they need to engage in E/PO. The identified barriers were consistent among scientists in GSFC's four science divisions (Earth science, planetary science, heliophysics, and astrophysics). Common barriers included 1) lack of time, 2) lack of funding support, 3) lack of value placed on doing E/PO by supervisors, 4) lack of training on doing appropriate/effective E/PO for different audiences, 5) lack of awareness and information about opportunities, 6) lack of understanding of what E/PO really is, and 7) level of effort required to do E/PO. Engineers reported similar issues, but the issues of time and funding support were more pronounced due to their highly structured work day and environment. Since the barriers were identified, the SCWG has taken a number of steps to address and rectify them. Steps have included holding various events to introduce scientists and engineers to E/PO staff and opportunities including an E/PO Open House, brown bag seminars on

  11. The Teaching of Sciences in African Universities. [Report of the Seminar on the Teaching of Basic Sciences in African Universities, Rabat, 13 to 22 December 1962].

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    Eighteen recommendations made by a 1962 United Nations Educational, Scientific and Cultural Organization (UNESCO) seminar on teaching the basic sciences in African universities introduce the conference report. A general summary of the conference proceedings, reported separately for pedagogic problems and difficulties of organization and…

  12. Addressing Common Student Technical Errors in Field Data Collection: An Analysis of a Citizen-Science Monitoring Project.

    PubMed

    Philippoff, Joanna; Baumgartner, Erin

    2016-03-01

    The scientific value of citizen-science programs is limited when the data gathered are inconsistent, erroneous, or otherwise unusable. Long-term monitoring studies, such as Our Project In Hawai'i's Intertidal (OPIHI), have clear and consistent procedures and are thus a good model for evaluating the quality of participant data. The purpose of this study was to examine the kinds of errors made by student researchers during OPIHI data collection and factors that increase or decrease the likelihood of these errors. Twenty-four different types of errors were grouped into four broad error categories: missing data, sloppiness, methodological errors, and misidentification errors. "Sloppiness" was the most prevalent error type. Error rates decreased with field trip experience and student age. We suggest strategies to reduce data collection errors applicable to many types of citizen-science projects including emphasizing neat data collection, explicitly addressing and discussing the problems of falsifying data, emphasizing the importance of using standard scientific vocabulary, and giving participants multiple opportunities to practice to build their data collection techniques and skills.

  13. Cannabinoid-Induced Hyperemesis: A Conundrum—From Clinical Recognition to Basic Science Mechanisms

    PubMed Central

    Darmani, Nissar A.

    2010-01-01

    Cannabinoids are used clinically on a subacute basis as prophylactic agonist antiemetics for the prevention of nausea and vomiting caused by chemotherapeutics. Cannabinoids prevent vomiting by inhibition of release of emetic neurotransmitters via stimulation of presynaptic cannabinoid CB1 receptors. Cannabis-induced hyperemesis is a recently recognized syndrome associated with chronic cannabis use. It is characterized by repeated cyclical vomiting and learned compulsive hot water bathing behavior. Although considered rare, recent international publications of numerous case reports suggest the contrary. The syndrome appears to be a paradox and the pathophysiological mechanism(s) underlying the induced vomiting remains unknown. Although some traditional hypotheses have already been proposed, the present review critically explores the basic science of these explanations in the clinical setting and provides more current mechanisms for the induced hyperemesis. These encompass: (1) pharmacokinetic factors such as long half-life, chronic exposure, lipid solubility, individual variation in metabolism/excretion leading to accumulation of emetogenic cannabinoid metabolites, and/or cannabinoid withdrawal; and (2) pharmacodynamic factors including switching of the efficacy of Δ9-THC from partial agonist to antagonist, differential interaction of Δ9-THC with Gs and Gi signal transduction proteins, CB1 receptor desensitization or downregulation, alterations in tissue concentrations of endocannabinoid agonists/inverse agonists, Δ9-THC-induced mobilization of emetogenic metabolites of the arachidonic acid cascade, brainstem versus enteric actions of Δ9-THC, and/or hypothermic versus hyperthermic actions of Δ9-THC. In addition, human and animal findings suggest that chronic exposure to cannabis may not be a prerequisite for the induction of vomiting but is required for the intensity of emesis. PMID:27713347

  14. Basic Energy Sciences Exascale Requirements Review. An Office of Science review sponsored jointly by Advanced Scientific Computing Research and Basic Energy Sciences, November 3-5, 2015, Rockville, Maryland

    SciTech Connect

    Clark, Aurora; Millis, Andy; Gagliardi, Laura; Panagiotopoulos, Thanos; Siepmann, Ilja; Wolverton, Chris; Vashishta, Priya; Stevens, Mark; Gordon, Mark; Kent, Paul; va DAm, Kerstin Kleese; Proffen, Thomas; Tull, Craig; Diachin, Lori; Sethian, Jamie; Benali, Anouar; Chen, Jackie; Antypas, Katie; Gerber, Richard; Riley, Katherine; Straatsma, Tjerk

    2015-12-31

    Computers have revolutionized every aspect of our lives. Yet in science, the most tantalizing applications of computing lie just beyond our reach. The current quest to build an exascale computer with one thousand times the capability of today’s fastest machines (and more than a million times that of a laptop) will take researchers over the next horizon. The field of materials, chemical reactions, and compounds is inherently complex. Imagine millions of new materials with new functionalities waiting to be discovered — while researchers also seek to extend those materials that are known to a dizzying number of new forms. We could translate massive amounts of data from high precision experiments into new understanding through data mining and analysis. We could have at our disposal the ability to predict the properties of these materials, to follow their transformations during reactions on an atom-by-atom basis, and to discover completely new chemical pathways or physical states of matter. Extending these predictions from the nanoscale to the mesoscale, from the ultrafast world of reactions to long-time simulations to predict the lifetime performance of materials, and to the discovery of new materials and processes will have a profound impact on energy technology. In addition, discovery of new materials is vital to move computing beyond Moore’s law. To realize this vision, more than hardware is needed. New algorithms to take advantage of the increase in computing power, new programming paradigms, and new ways of mining massive data sets are needed as well. This report summarizes the opportunities and the requisite computing ecosystem needed to realize the potential before us. In addition to pursuing new and more complete physical models and theoretical frameworks, this review found that the following broadly grouped areas relevant to the U.S. Department of Energy (DOE) Office of Advanced Scientific Computing Research (ASCR) would directly affect the Basic Energy

  15. Science and Theatre Education: A Cross-disciplinary Approach of Scientific Ideas Addressed to Student Teachers of Early Childhood Education

    NASA Astrophysics Data System (ADS)

    Tselfes, Vasilis; Paroussi, Antigoni

    2009-09-01

    There is, in Greece, an ongoing attempt to breach the boundaries established between the different teaching-learning subjects of compulsory education. In this context, we are interested in exploring to what degree the teaching and learning of ideas from the sciences’ “internal life” (Hacking, in: Pickering (ed) Science as practice and culture, 1992) benefits from creatively coming into contact with theatrical education as part of the corresponding curriculum subject. To this end, 57 students of the Early Childhood Education Department of the University of Athens were called to study extracts from Galileo’s Dialogue Concerning the Two Chief World Systems, Ptolemaic and Copernican, to focus on a subject that the Dialogue’s “interlocutors” forcefully disagree about and to theatrically represent (using shadow theatre techniques) what they considered as being the central idea of this clash of opinions. The results indicate that this attempt leads to a satisfactory understanding of ideas relating to the content and methodology of the natural sciences. At the same time, theatrical education avails itself of the representation of scientific ideas and avoids the clichés and hackneyed techniques that the (often) simplistic choices available in the educational context of early childhood education tend towards. The basic reasons for both facets of this success are: (a) Genuine scientific texts force the students to approach them with seriousness, and all the more so if these recount the manner in which scientific ideas are produced and are embedded in the historical and social context of the age that created them; (b) The theatrical framework, which essentially guides the students’ activities, allows (if not obliges) them to approach scientific issues creatively; in other words, it allows them to create something related to science and recognize it as theirs; and, (c) Both the narrative texts describing processes of “science making” (Bruner, J Sci Educ

  16. Reinventing Biostatistics Education for Basic Scientists

    PubMed Central

    Weissgerber, Tracey L.; Garovic, Vesna D.; Milin-Lazovic, Jelena S.; Winham, Stacey J.; Obradovic, Zoran; Trzeciakowski, Jerome P.; Milic, Natasa M.

    2016-01-01

    Numerous studies demonstrating that statistical errors are common in basic science publications have led to calls to improve statistical training for basic scientists. In this article, we sought to evaluate statistical requirements for PhD training and to identify opportunities for improving biostatistics education in the basic sciences. We provide recommendations for improving statistics training for basic biomedical scientists, including: 1. Encouraging departments to require statistics training, 2. Tailoring coursework to the students’ fields of research, and 3. Developing tools and strategies to promote education and dissemination of statistical knowledge. We also provide a list of statistical considerations that should be addressed in statistics education for basic scientists. PMID:27058055

  17. Reinventing Biostatistics Education for Basic Scientists.

    PubMed

    Weissgerber, Tracey L; Garovic, Vesna D; Milin-Lazovic, Jelena S; Winham, Stacey J; Obradovic, Zoran; Trzeciakowski, Jerome P; Milic, Natasa M

    2016-04-01

    Numerous studies demonstrating that statistical errors are common in basic science publications have led to calls to improve statistical training for basic scientists. In this article, we sought to evaluate statistical requirements for PhD training and to identify opportunities for improving biostatistics education in the basic sciences. We provide recommendations for improving statistics training for basic biomedical scientists, including: 1. Encouraging departments to require statistics training, 2. Tailoring coursework to the students' fields of research, and 3. Developing tools and strategies to promote education and dissemination of statistical knowledge. We also provide a list of statistical considerations that should be addressed in statistics education for basic scientists.

  18. Retention of knowledge and perceived relevance of basic sciences in an integrated case-based learning (CBL) curriculum

    PubMed Central

    2013-01-01

    Background Knowledge and understanding of basic biomedical sciences remain essential to medical practice, particularly when faced with the continual advancement of diagnostic and therapeutic modalities. Evidence suggests, however, that retention tends to atrophy across the span of an average medical course and into the early postgraduate years, as preoccupation with clinical medicine predominates. We postulated that perceived relevance demonstrated through applicability to clinical situations may assist in retention of basic science knowledge. Methods To test this hypothesis in our own medical student cohort, we administered a paper-based 50 MCQ assessment to a sample of students from Years 2 through 5. Covariates pertaining to demographics, prior educational experience, and the perceived clinical relevance of each question were also collected. Results A total of 232 students (Years 2–5, response rate 50%) undertook the assessment task. This sample had comparable demographic and performance characteristics to the whole medical school cohort. In general, discipline-specific and overall scores were better for students in the latter years of the course compared to those in Year 2; male students and domestic students tended to perform better than their respective counterparts in certain disciplines. In the clinical years, perceived clinical relevance was significantly and positively correlated with item performance. Conclusions This study suggests that perceived clinical relevance is a contributing factor to the retention of basic science knowledge and behoves curriculum planners to make clinical relevance a more explicit component of applied science teaching throughout the medical course. PMID:24099045

  19. Progress of basic research in Parkinson's disease in China: data mini-review from the National Natural Science Foundation.

    PubMed

    Cao, Heqi; Chen, Gang; Dong, Erdan

    2013-08-30

    This review is to analyze the role of National Natural Science Foundation of China (NSFC) on the development of basic research of Parkinson's disease from 1990 to 2012. Data on the total number of projects and funding of NSFC allocated to Parkinson's disease, as well as hotspots in western countries, papers published, awards, personnel training, subject construction were collected, and the role of NSFC on other sources of funding was evaluated. Over the past 23 years, a full range of continuous funding from NSFC has led to fruitful results and a strong impetus to the progress of basic research of Parkinson's disease.

  20. Opportunities to Learn in School and at Home: How can they predict students' understanding of basic science concepts and principles?

    NASA Astrophysics Data System (ADS)

    Wang, Su; Liu, Xiufeng; Zhao, Yandong

    2012-09-01

    As the breadth and depth of economic reforms increase in China, growing attention is being paid to equalities in opportunities to learn science by students of various backgrounds. In early 2009, the Chinese Ministry of Education and Ministry of Science and Technology jointly sponsored a national survey of urban eighth-grade students' science literacy along with their family and school backgrounds. The present study focused on students' understanding of basic science concepts and principles (BSCP), a subset of science literacy. The sample analyzed included 3,031 students from 109 randomly selected classes/schools. Correlation analysis, one-way analysis of variance, and two-level linear regression were conducted. The results showed that having a refrigerator, internet, more books, parents purchasing books and magazines related to school work, higher father's education level, and parents' higher expectation of the education level of their child significantly predicted higher BSCP scores; having siblings at home, owning an apartment, and frequently contacting teachers about the child significantly predicted lower BSCP scores. At the school level, the results showed that being in the first-tier or key schools, having school libraries, science popularization galleries, computer labs, adequate equipment for teaching, special budget for teacher training, special budget for science equipment, and mutual trust between teachers and students significantly predicated higher BSCP scores; and having science and technology rooms, offering science and technology interest clubs, special budget for science curriculum development, and special budget for science social practice activities significantly predicted lower BSCP scores. The implications of the above findings are discussed.

  1. The Relationship between Preservice Science Teachers' Attitude toward Astronomy and Their Understanding of Basic Astronomy Concepts

    ERIC Educational Resources Information Center

    Bektasli, Behzat

    2016-01-01

    Turkish preservice science teachers have been taking a two-credit astronomy class during the last semester of their undergraduate program since 2010. The current study aims to investigate the relationship between preservice science teachers' astronomy misconceptions and their attitudes toward astronomy. Preservice science teachers were given an…

  2. Alternative Methods by Which Basic Science Pharmacy Faculty Can Relate to Clinical Practice, Executive Summary and Final Report, October 1, 1978 - March 15, 1980.

    ERIC Educational Resources Information Center

    Kabat, Hugh F.; And Others

    The areas of basic science pharmacy instruction and clinical pharmacy practice and their interrelationships were identified in order to help develop didactic and clinical experience alternatives. A 10-member advisory committee ranked basic pharmaceutical science topical areas in terms of their applicability to clinical practice utilizing a Delphi…

  3. A case-based, small-group cooperative learning course in preclinical veterinary science aimed at bridging basic science and clinical literacy.

    PubMed

    Schoeman, J P; van Schoor, M; van der Merwe, L L; Meintjes, R A

    2009-03-01

    In 1999 a dedicated problem-based learning course was introduced into the lecture-based preclinical veterinary curriculum of the University of Pretoria. The Introduction to Clinical Studies Course combines traditional lectures, practical sessions, student self-learning and guided tutorials. The self-directed component of the course utilises case-based, small-group cooperative learning as an educational vehicle to link basic science with clinical medicine. The aim of this article is to describe the objectives and structure of the course and to report the results of the assessment of the students' perceptions on some aspects of the course. Students reacted very positively to the ability of the course to equip them with problem-solving skills. Students indicated positive perceptions about the workload of the course. There were, however, significantly lower scores for the clarity of the course objectives. Although the study guide for the course is very comprehensive, the practice regarding the objectives is still uncertain. It is imperative to set clear objectives in non-traditional, student-centred courses. The objectives have to be explained at the outset and reiterated throughout the course. Tutors should also communicate the rationale behind problem-based learning as a pedagogical method to the students. Further research is needed to verify the effectiveness of this course in bridging the gap between basic science and clinical literacy in veterinary science. Ongoing feedback and assessment of the management and content are important to refine this model for integrating basic science with clinical literacy.

  4. Enhancing Science Teaching through Performing Marbling Art Using Basic Solutions and Base Indicators

    ERIC Educational Resources Information Center

    Çil, Emine; Çelik, Kevser; Maçin, Tuba; Demirbas, Gülay; Gökçimen, Özlem

    2014-01-01

    Basic solutions are an indispensable part of our daily life. Basic solutions are commonly used in industries such as the textile industry, oil refineries, the fertilizer industry, and pharmaceutical products. Most cleaning agents, such as soap, detergent, and bleach, and some of our foods, such as chocolate and eggs, include bases. Bases are the…

  5. Basic and Applied Materials Science Research Efforts at MSFC Germane to NASA Goals

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Presently, a number of investigations are ongoing that blend basic research with engineering applications in support of NASA goals. These include (1) "Pore Formation and Mobility (PFMI) " An ISS Glovebox Investigation" NASA Selected Project - 400-34-3D; (2) "Interactions Between Rotating Bodies" Center Director's Discretionary Fund (CDDF) Project - 279-62-00-16; (3) "Molybdenum - Rhenium (Mo-Re) Alloys for Nuclear Fuel Containment" TD Collaboration - 800-11-02; (4) "Fabrication of Alumina - Metal Composites for Propulsion Components" ED Collaboration - 090-50-10; (5) "Radiation Shielding for Deep-Space Missions" SD Effort; (6) "Other Research". In brief, "Pore Formation and Mobility" is an experiment to be conducted in the ISS Microgravity Science Glovebox that will systematically investigate the development, movement, and interactions of bubbles (porosity) during the controlled directional solidification of a transparent material. In addition to promoting our general knowledge of porosity physics, this work will serve as a guide to future ISS experiments utilizing metal alloys. "Interactions Between Rotating Bodies" is a CDDF sponsored project that is critically examining, through theory and experiment, claims of "new" physics relating to gravity modification and electric field effects. "Molybdenum - Rhenium Alloys for Nuclear Fuel Containment" is a TD collaboration in support of nuclear propulsion. Mo-Re alloys are being evaluated and developed for nuclear fuel containment. "Fabrication of Alumina - Metal Composites for Propulsion Components" is an ED collaboration with the intent of increasing strength and decreasing weight of metal engine components through the incorporation of nanometer-sized alumina fibers. "Radiation Shielding for Deep-Space Missions" is an SD effort aimed at minimizing the health risk from radiation to human space voyagers; work to date has been primarily programmatic but experiments to develop hydrogen-rich materials for shielding are

  6. Basic science and clinical application of stem cells in veterinary medicine.

    PubMed

    Ribitsch, I; Burk, J; Delling, U; Geißler, C; Gittel, C; Jülke, H; Brehm, W

    2010-01-01

    :329-336, 2008). It is believed that these stem cells serve as cell source to maintain tissue and organ mass during normal cell turnover in adult individuals. Therefore, the focus of attention in veterinary science is currently drawn to adult stem cells and their potential in regenerative medicine. Also experience gained from the treatment of animal patients provides valuable information for human medicine and serves as precursor to future stem cell use in human medicine.Compared to human medicine, haematopoietic stem cells only play a minor role in veterinary medicine because medical conditions requiring myeloablative chemotherapy followed by haematopoietic stem cell induced recovery of the immune system are relatively rare and usually not being treated for monetary as well as animal welfare reasons.In contrast, regenerative medicine utilising MSCs for the treatment of acute injuries as well as chronic disorders is gradually turning into clinical routine. Therefore, MSCs from either extra embryonic or adult tissues are in the focus of attention in veterinary medicine and research. Hence the purpose of this chapter is to offer an overview on basic science and clinical application of MSCs in veterinary medicine.

  7. Fort Collins Science Center Ecosystem Dynamics branch--interdisciplinary research for addressing complex natural resource issues across landscapes and time

    USGS Publications Warehouse

    Bowen, Zachary H.; Melcher, Cynthia P.; Wilson, Juliette T.

    2013-01-01

    The Ecosystem Dynamics Branch of the Fort Collins Science Center offers an interdisciplinary team of talented and creative scientists with expertise in biology, botany, ecology, geology, biogeochemistry, physical sciences, geographic information systems, and remote-sensing, for tackling complex questions about natural resources. As demand for natural resources increases, the issues facing natural resource managers, planners, policy makers, industry, and private landowners are increasing in spatial and temporal scope, often involving entire regions, multiple jurisdictions, and long timeframes. Needs for addressing these issues include (1) a better understanding of biotic and abiotic ecosystem components and their complex interactions; (2) the ability to easily monitor, assess, and visualize the spatially complex movements of animals, plants, water, and elements across highly variable landscapes; and (3) the techniques for accurately predicting both immediate and long-term responses of system components to natural and human-caused change. The overall objectives of our research are to provide the knowledge, tools, and techniques needed by the U.S. Department of the Interior, state agencies, and other stakeholders in their endeavors to meet the demand for natural resources while conserving biodiversity and ecosystem services. Ecosystem Dynamics scientists use field and laboratory research, data assimilation, and ecological modeling to understand ecosystem patterns, trends, and mechanistic processes. This information is used to predict the outcomes of changes imposed on species, habitats, landscapes, and climate across spatiotemporal scales. The products we develop include conceptual models to illustrate system structure and processes; regional baseline and integrated assessments; predictive spatial and mathematical models; literature syntheses; and frameworks or protocols for improved ecosystem monitoring, adaptive management, and program evaluation. The descriptions

  8. The use of self-learning modules to facilitate learning of basic science concepts in an integrated medical curriculum.

    PubMed

    Khalil, Mohammed K; Nelson, Loren D; Kibble, Jonathan D

    2010-01-01

    This study used qualitative and quantitative approaches to evaluate the effectiveness of self-learning modules (SLMs) developed to facilitate and individualize students' learning of basic medical sciences. Twenty physiology and nineteen microanatomy SLMs were designed with interactive images, animations, narrations, and self-assessments. Of 41 medical students, 40 students voluntarily completed a questionnaire with open-ended and closed-ended items to evaluate students' attitudes and perspectives on the learning value of SLMs. Closed-ended items were assessed on a five-point Likert scale (5 = high score) and the data were expressed as mean ± standard deviation. Open-ended questions further evaluated students' perspectives on the effectiveness of SLMs; student responses to open-ended questions were analyzed to identify shared patterns or themes in their experience using SLMs. The results of the midterm examination were also analyzed to compare student performance on items related to SLMs and traditional sessions. Students positively evaluated their experience using the SLMs with an overall mean score of 4.25 (SD ± 0.84). Most students (97%) indicated that the SLMs improved understanding and facilitated learning basic science concepts. SLMs were reported to allow learner control, to help in preparation for subsequent in-class discussion, and to improve understanding and retention. A significant difference in students' performance was observed when comparing SLM-related items with non-SLM items in the midterm examination (P < 0.05). In conclusion, the use of SLMs in an integrated basic science curriculum has the potential to individualize the teaching and improve the learning of basic sciences.

  9. Exploring Ivorian Perspectives on the Effectiveness of the Current Ivorian Science Curriculum in Addressing Issues Related to HIV/AIDS

    ERIC Educational Resources Information Center

    Ado, Gustave Firmin

    2014-01-01

    School-based HIV/AIDS science education has the potential to impact students when integrated into the science curriculum. However, this mixed method study shows that school-based HIV/AIDS science education is often not infused into career subjects such as science education but integrated into civics education and taught by teachers who lack the…

  10. BASIC Simulation Programs; Volumes I and II. Biology, Earth Science, Chemistry.

    ERIC Educational Resources Information Center

    Digital Equipment Corp., Maynard, MA.

    Computer programs which teach concepts and processes related to biology, earth science, and chemistry are presented. The seven biology problems deal with aspects of genetics, evolution and natural selection, gametogenesis, enzymes, photosynthesis, and the transport of material across a membrane. Four earth science problems concern climates, the…

  11. Science: A Practical View. Volume III. Teacher Edition. Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the third in a series of three, provides the intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) the scientific principles of…

  12. Science: A Practical View. Volume II. Teacher Edition. Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the second in a series of three, provides the intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The guide is divided into three components. The first component helps students…

  13. Science: A Practical View. Volume I. Teacher Edition. Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the first in a series of three, provides the intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) ecology (what marine science…

  14. Basic Science Process Skills. An Inservice Workshop Kit: Outlines and Activities.

    ERIC Educational Resources Information Center

    Rowland, Paul; And Others

    A science process skill project was developed to help elementary teachers meet competency standards in New Mexico for teaching the process approach in their science classes. An outline of the process skills along with recommended activities are presented in this document. Performance objectives are identified and a sample activity form is…

  15. Basic Concepts in the Methodology of the Social Sciences. HSRC Studies in Research Methodology.

    ERIC Educational Resources Information Center

    Mouton, Johann, Ed.; Marais, H. C.

    Considerations of validity that are central to all disciplines in the social sciences are discussed, and concepts that are an essential part of the intellectual equipment of the social sciences researcher are systematically analyzed. Fundamental methodological concepts underlying decisions made in the research process are highlighted to encourage…

  16. Regime, phase and paradigm shifts: making community ecology the basic science for fisheries

    PubMed Central

    Mangel, Marc; Levin, Phillip S.

    2005-01-01

    Modern fishery science, which began in 1957 with Beverton and Holt, is ca. 50 years old. At its inception, fishery science was limited by a nineteenth century mechanistic worldview and by computational technology; thus, the relatively simple equations of population ecology became the fundamental ecological science underlying fisheries. The time has come for this to change and for community ecology to become the fundamental ecological science underlying fisheries. This point will be illustrated with two examples. First, when viewed from a community perspective, excess production must be considered in the context of biomass left for predators. We argue that this is a better measure of the effects of fisheries than spawning biomass per recruit. Second, we shall analyse a simple, but still multi-species, model for fishery management that considers the alternatives of harvest regulations, inshore marine protected areas and offshore marine protected areas. Population or community perspectives lead to very different predictions about the efficacy of reserves. PMID:15713590

  17. Basic Research Needs for Solar Energy Utilization. Report of the Basic Energy Sciences Workshop on Solar Energy Utilization, April 18-21, 2005

    SciTech Connect

    Lewis, N. S.; Crabtree, G.; Nozik, A. J.; Wasielewski, M. R.; Alivisatos, P.; Kung, H.; Tsao, J.; Chandler, E.; Walukiewicz, W.; Spitler, M.; Ellingson, R.; Overend, R.; Mazer, J.; Gress, M.; Horwitz, J.; Ashton, C.; Herndon, B.; Shapard, L.; Nault, R. M.

    2005-04-21

    World demand for energy is projected to more than double by 2050 and to more than triple by the end of the century. Incremental improvements in existing energy networks will not be adequate to supply this demand in a sustainable way. Finding sufficient supplies of clean energy for the future is one of society?s most daunting challenges. Sunlight provides by far the largest of all carbon-neutral energy sources. More energy from sunlight strikes the Earth in one hour (4.3 ? 1020 J) than all the energy consumed on the planet in a year (4.1 ? 1020 J). We currently exploit this solar resource through solar electricity ? a $7.5 billion industry growing at a rate of 35?40% per annum ? and solar-derived fuel from biomass, which provides the primary energy source for over a billion people. Yet, in 2001, solar electricity provided less than 0.1% of the world's electricity, and solar fuel from modern (sustainable) biomass provided less than 1.5% of the world's energy. The huge gap between our present use of solar energy and its enormous undeveloped potential defines a grand challenge in energy research. Sunlight is a compelling solution to our need for clean, abundant sources of energy in the future. It is readily available, secure from geopolitical tension, and poses no threat to our environment through pollution or to our climate through greenhouse gases. This report of the Basic Energy Sciences Workshop on Solar Energy Utilization identifies the key scientific challenges and research directions that will enable efficient and economic use of the solar resource to provide a significant fraction of global primary energy by the mid 21st century. The report reflects the collective output of the workshop attendees, which included 200 scientists representing academia, national laboratories, and industry in the United States and abroad, and the U.S. Department of Energy?s Office of Basic Energy Sciences and Office of Energy Efficiency and Renewable Energy.

  18. Report of the joint ESOT and TTS basic science meeting 2013: current concepts and discoveries in translational transplantation.

    PubMed

    Ebner, Susanne; Fabritius, Cornelia; Ritschl, Paul; Oberhuber, Rupert; Günther, Julia; Kotsch, Katja

    2014-10-01

    A joint meeting organized by the European (ESOT) and The Transplantation (TTS) Societies for basic science research was organized in Paris, France, on November 7-9, 2013. Focused on new ideas and concepts in translational transplantation, the meeting served as a venue for state-of-the-art developments in basic transplantation immunology, such as the potential for tolerance induction through regulation of T-cell signaling. This meeting report summarizes important insights which were presented in Paris. It not only offers an overview of established aspects, such as the role of Tregs in transplantation, presented by Nobel laureate Rolf Zinkernagel, but also highlights novel facets in the field of transplantation, that is cell-therapy-based immunosuppression or composite tissue transplantation as presented by the emotional story given by Vasyly Rohovyy, who received two hand transplants. The ESOT/TTS joint meeting was an overall productive and enjoyable platform for basic science research in translational transplantation and fulfilled all expectations by giving a promising outlook for the future of research in the field of immunological transplantation research.

  19. National Institutes of Health Update: Translating Basic Behavioral Science into New Pediatric Obesity Interventions.

    PubMed

    Czajkowski, Susan M

    2016-06-01

    Pediatric obesity increases the risk of later-life obesity and chronic diseases. Basic research to better understand factors associated with excessive weight gain in early life and studies translating research findings into preventive and therapeutic strategies are essential to our ability to better prevent and treat childhood obesity. This overview describes several National Institutes of Health efforts designed to stimulate basic and translational research in childhood obesity prevention and treatment. These examples demonstrate the value of research in early phase translational pediatric obesity research and highlight some promising directions for this important area of research.

  20. Teaching Skills to Promote Clinical Reasoning in Early Basic Science Courses

    ERIC Educational Resources Information Center

    Elizondo-Omana, Rodrigo Enrique; Morales-Gomez, Jesus Alberto; Morquecho-Espinoza, Orlando; Hinojosa-Amaya, Jose Miguel; Villarreal-Silva, Eliud Enrique; Garcia-Rodriguez, Maria de los Angeles; Guzman-Lopez, Santos

    2010-01-01

    Basic and superior reasoning skills are woven into the clinical reasoning process just as they are used to solve any problem. As clinical reasoning is the central competence of medical education, development of these reasoning skills should occur throughout the undergraduate medical curriculum. The authors describe here a method of teaching…

  1. Issue 1979--Bridging the Gap Between the Basic Sciences and Clinical Practice: Teaching, Research, and Service.

    ERIC Educational Resources Information Center

    DiBiaggio, John A.

    1980-01-01

    Suggestions are made for reducing tension between clinical practice and basic research segments of pharmacy: develop mutual respect among all faculty segments, combine research efforts, modify the reward system for greater equity, increase physical proximity, share experiences through clinics and forums, and combine realism with tradition. (MSE)

  2. Basic science with pulsed power & some off-the-wall ideas

    SciTech Connect

    Solem, J.C.

    1995-04-01

    This paper discusses aspects of pulsed power for use in basic research, with a principal emphasis on ATLAS, a planned 36-MJ pulsed-power machine with a circular architechture designed primarily for z-pinch implosion of cylindrical foils. The objective of the paper is to give an overview and touch on subjects which might test the limits of this technology.

  3. The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions.

    PubMed

    Gilliland, C Taylor; Sittampalam, G Sitta; Wang, Philip Y; Ryan, Philip E

    2017-01-02

    Translational science is an emerging field that holds great promise to accelerate the development of novel medical interventions. As the field grows, so does the demand for highly trained biomedical scientists to fill the positions that are being created. Many graduate and postdoctorate training programs do not provide their trainees with sufficient education to take advantage of this growing employment sector. To help better prepare the trainees at the National Institutes of Health for possible careers in translation, we have created the Translational Science Training Program (TSTP). The TSTP is an intensive 2- to 3-day training program that introduces NIH postdoctoral trainees and graduate students to the science and operation of turning basic research discoveries into a medical therapeutic, device or diagnostic, and also exposes them to the variety of career options in translational science. Through a combination of classroom teaching from practicing experts in the various disciplines of translation and small group interactions with pre-clinical development teams, participants in the TSTP gain knowledge that will aid them in obtaining a career in translational science and building a network to make the transition to the field. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(1):13-24, 2017.

  4. ``The ESA XMM-Newton Science Operations Centre: Making Basic Space Science Available to the Whole Scientific World''

    NASA Astrophysics Data System (ADS)

    Gabriel, Carlos; Guainazzi, Matteo; Metcalfe, Leo

    2006-12-01

    XMM-Newton is a major X-ray observatory of the European Space Agency (ESA). Its observing time is open to astronomers from the whole scientific community on a peer reviewed competitive basis. The Science Operations Centre, located at ESA’s premises in Villafranca del Castillo, Spain, is responsible for the instrument operations, as well as for all the tasks related to facilitating the scientific exploitation of the data which the mission has been producing since its launch in December 1999. Among them, one may list: distribution of scientific data in different formats, from raw telemetry, up to processed and calibrated high-level science products, such as images, spectra, source lists, etc; development and distribution of dedicated science analysis software, as well as of continuously updated instrument calibration; regular organisation of training workshops (free of cost), for potential users of XMM-Newton data, where the procedures and techniques to successfully reduce and analyze XMM-Newton data are introduced; access to the data through state-of-the-art, in-house-developed archival facilities, either through the Internet or via CD-ROM; continuously updated documentation on all aspects of spacecraft and instrument operations, data reduction and analysis; maintenance of a comprehensive set of project web pages; a competent and responsive HelpDesk, providing dedicated support to individual XMM-Newton users. Everyone can be an XMM-Newton observer. So far, astronomers from 36 countries submitted observing programs. Public data can be accessed by every scientist in the world through the XMM-Newton Science Archive (XSA). Despite

  5. User Facilities of the Office of Basic Energy Sciences: A National Resource for Scientific Research

    SciTech Connect

    2009-01-01

    The BES user facilities provide open access to specialized instrumentation and expertise that enable scientific users from universities, national laboratories, and industry to carry out experiments and develop theories that could not be done at their home institutions. These forefront research facilities require resource commitments well beyond the scope of any non-government institution and open up otherwise inaccessible facets of Nature to scientific inquiry. For approved, peer-reviewed projects, instrument time is available without charge to researchers who intend to publish their results in the open literature. These large-scale user facilities have made significant contributions to various scientific fields, including chemistry, physics, geology, materials science, environmental science, biology, and biomedical science. Over 16,000 scientists and engineers.pdf file (27KB) conduct experiments at BES user facilities annually. Thousands of other researchers collaborate with these users and analyze the data measured at the facilities to publish new scientific findings in peer-reviewed journals.

  6. Developing a competency-based medical education curriculum for the core basic medical sciences in an African Medical School

    PubMed Central

    Olopade, Funmilayo Eniola; Adaramoye, Oluwatosin Adekunle; Raji, Yinusa; Fasola, Abiodun Olubayo; Olapade-Olaopa, Emiola Oluwabunmi

    2016-01-01

    The College of Medicine of the University of Ibadan recently revised its MBBS and BDS curricula to a competency-based medical education method of instruction. This paper reports the process of revising the methods of instruction and assessment in the core basic medical sciences directed at producing medical and dental graduates with a sound knowledge of the subjects sufficient for medical and dental practice and for future postgraduate efforts in the field or related disciplines. The health needs of the community and views of stakeholders in the Ibadan medical and dental schools were determined, and the “old” curriculum was reviewed. This process was directed at identifying the strengths and weaknesses of the old curricula and the newer competences required for modern-day medical/dental practice. The admission criteria and processes and the learning methods of the students were also studied. At the end of the review, an integrated, system-based, community-oriented, person-centered, and competency-driven curriculum was produced and approved for implementation. Four sets of students have been admitted into the curriculum. There have been challenges to the implementation process, but these have been overcome by continuous faculty development and reorientation programs for the nonteaching staff and students. Two sets of students have crossed over to the clinical school, and the consensus among the clinical teachers is that their knowledge and application of the basic medical sciences are satisfactory. The Ibadan medical and dental schools are implementing their competency-based medical education curricula successfully. The modifications to the teaching and assessment of the core basic medical science subjects have resulted in improved learning and performance at the final examinations. PMID:27486351

  7. Reproducibility in science: improving the standard for basic and preclinical research.

    PubMed

    Begley, C Glenn; Ioannidis, John P A

    2015-01-02

    Medical and scientific advances are predicated on new knowledge that is robust and reliable and that serves as a solid foundation on which further advances can be built. In biomedical research, we are in the midst of a revolution with the generation of new data and scientific publications at a previously unprecedented rate. However, unfortunately, there is compelling evidence that the majority of these discoveries will not stand the test of time. To a large extent, this reproducibility crisis in basic and preclinical research may be as a result of failure to adhere to good scientific practice and the desperation to publish or perish. This is a multifaceted, multistakeholder problem. No single party is solely responsible, and no single solution will suffice. Here we review the reproducibility problems in basic and preclinical biomedical research, highlight some of the complexities, and discuss potential solutions that may help improve research quality and reproducibility.

  8. Soil Science. III-A-1 to III-D-4. Basic V.A.I.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station. Vocational Instructional Services.

    This packet contains four units of informational materials and transparency masters, with accompanying scripts, for teachers to use in a soil science course in vocational agriculture. Designed especially for use in Texas, the first unit discusses the importance of soils. In the second unit, the nature and properties of soils are discussed,…

  9. Colloquium on Selected Topics in Behavioral Science Basic Research. (Alexandria, Virginia, April 23-25, 1980).

    ERIC Educational Resources Information Center

    Nogami, Glenda Y., Ed.; And Others

    The 21 summaries of research programs, funded by the United States Army Research Institute (ARI) for the Behavioral and Social Sciences which are presented are grouped in five broad topic areas: computer-based systems; information processing; learning, memory and transfer; human relations; and related issues and trends. Papers presented include:…

  10. Chemical Nanotechnology: A Liberal Arts Approach to a Basic Course in Emerging Interdisciplinary Science and Technology

    ERIC Educational Resources Information Center

    Porter, Lon A., Jr.

    2007-01-01

    The nanotechnology degree programs initiated at various institutions provided an excellent way of learning to look at the amazing opportunities that arise when various disciplines of science interact. The enrolled students were actively engaged in the subject matter and also expressed greater confidence in their ability to consider technology with…

  11. Resource Handbook: The Earth. A Supplement to Basic Curriculum Guide--Science, Grades K-6.

    ERIC Educational Resources Information Center

    Starr, John W., 3rd., Ed.

    GRADES OR AGES: Grades K-6. SUBJECT MATTER: Science; the earth. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is in three main parts: 1) atmosphere; 2) lithosphere; and 3) hydrosphere. Each section is subdivided into initiatory activities, developmental activities, evaluations, vocabulary, children's books, and films. The guide is mimeographed…

  12. The value of public health research and the division between basic vs. applied science.

    PubMed

    Almeida-Filho, Namoar; Goldbaum, Moisés

    2003-02-01

    We question the movement towards exclusion of population and social health research from the field of science. The background under analysis is contemporary Brazil, where the scientific field that hosts this kind of research is known as Collective Health. First, the problem is formalized on logical grounds, evaluating the pertinence of considering unscientific the many objects and methods of public health research. Secondly, the cases of pulmonary tuberculosis and external causes are brought in as illustrations of the kind of scientific problem faced in health research today. The logical and epistemological basis of different forms of "scientific segregation" based on biomedical reductionism is analyzed, departing from three theses: (i) the ethics of the general application of science; (ii) the inappropriateness of monopolies for objectivity in the sciences; (iii) the specificity of scientific fields. In the current panorama of health research in Brazil, a residual hegemonic position that defends a narrow and specific definition of the object of knowledge was found. The denial of validity and specificity to objects, methods and research techniques that constitute social and population research in health is linked to elements of irrationality in reductionism approaches. Nevertheless, efforts should be directed to overcome this scientific division, in order to develop a pluralist and interdisciplinary national science, committed to the health care realities of our country.

  13. Learning Environments as Basis for Cognitive Achievements of Students in Basic Science Classrooms in Nigeria

    ERIC Educational Resources Information Center

    Atomatofa, Rachel; Okoye, Nnamdi; Igwebuike, Thomas

    2016-01-01

    The nature of classroom learning environments created by teachers had been considered very important for learning to take place effectively. This study investigated the effect of creating constructivist and transmissive learning environments on achievements of science students of different ability levels. 243 students formed the entire study…

  14. Animal Science Basic Core Curriculum. Kansas Postsecondary Farm and Ranch Management Project.

    ERIC Educational Resources Information Center

    Albracht, James, Ed.

    Thirty-six units of instruction are included in this core curriculum in animal science for postsecondary farm and ranch management programs. Units of instruction are divided into seven instructional areas: (1) Livestock Types, (2) Livestock Programs, (3) Nutrition, (4) Animal Health, (5) Animal Breeding, (6) Animal Improvement, and (7) Livestock…

  15. Plant Science. IV-A-1 to IV-F-2. Basic V.A.I.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station. Vocational Instructional Services.

    This packet contains six units of informational materials and transparency masters, with accompanying scripts, for teachers to use in a plant science course in vocational agriculture. Designed especially for use in Texas, the first unit introduces the course through the following topics: economic importance of major crops, major areas of…

  16. Electronic Components, Transducers, and Basic Circuits. A Study Guide of the Science and Engineering Technician Curriculum.

    ERIC Educational Resources Information Center

    Mowery, Donald R.

    This study guide is part of a program of studies entitled the Science and Engineering Technician (SET) Curriculum developed for the purpose of training technicians in the use of electronic instruments and their applications. The program integrates elements from the disciplines of chemistry, physics, mathematics, mechanical technology, and…

  17. Science and Theatre Education: A Cross-Disciplinary Approach of Scientific Ideas Addressed to Student Teachers of Early Childhood Education

    ERIC Educational Resources Information Center

    Tselfes, Vasilis; Paroussi, Antigoni

    2009-01-01

    There is, in Greece, an ongoing attempt to breach the boundaries established between the different teaching-learning subjects of compulsory education. In this context, we are interested in exploring to what degree the teaching and learning of ideas from the sciences' "internal life" (Hacking, in: Pickering (ed) "Science as practice…

  18. Proposal to DOE Basic Energy Sciences: Ultrafast X-ray science facility at the Advanced Light Source

    SciTech Connect

    Schoenlein, Robert W.; Falcone, Roger W.; Abela, R.; Alivisatos, A.P.; Belkacem, A.; Berrah, N.; Bozek, J.; Bressler, C.; Cavalleri, A.; Chergui, M.; Glover, T.E.; Heimann, P.A.; Hepburn, J.; Larsson, J.; Lee, R.W.; McCusker, J.; Padmore, H.A.; Pattison, P.; Pratt, S.T.; Shank, C.V.; Wark, J.; Chang, Z.; Robin, D.W.; Schlueter, R.D.; Zholents, A.A.; Zolotorev, M.S.

    2001-12-12

    We propose to develop a true user facility for ultrafast x-ray science at the Advanced Light Source. This facility will be unique in the world, and will fill a critical need for the growing ultrafast x-ray research community. The development of this facility builds upon the expertise from long-standing research efforts in ultrafast x-ray spectroscopy and the development of femtosecond x-ray sources and techniques at both the Lawrence Berkeley National Laboratory and at U.C. Berkeley. In particular, the technical feasibility of a femtosecond x-ray beamline at the ALS has already been demonstrated, and existing ultrafast laser technology will enable such a beamline to operate near the practical limit for femtosecond x-ray flux and brightness from a 3rd generation synchrotron.

  19. Basic Science of the Fundamentals and Dynamics of Social-Fringe Group Formation and Sustainment

    DTIC Science & Technology

    2012-08-01

    workshop!where! international !thought!leaders!could! interact!while!being!pressed!to!identify!leading!researchable!questions!that!push!at! the... International Relations (2) Social Psychology (4) Anthropology (2) Cognitive Sciences Industrial and Organit:at’lonal psychology (3) SOCIOlogy (3...Middle dass & civlt society, ethnicity SociaJ Relations (Ethnic, fthgiou.s, gender) Social Values & Survey Research HCI & Computer-Supported Coop

  20. Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology.

    PubMed Central

    Stapleton, M P

    1997-01-01

    The history of cardiology encompasses some of the most revered names in medical history, many belonging to physicians who have advanced knowledge beyond their time. However, there have been countless others whose work in the basic sciences has paid large dividends to clinical cardiology. The original example of such an individual is William Harvey, whose reasoned experimentation led to the understanding of the circulation of blood. Another such man, Sir James Black, has contributed to basic scientific and clinical knowledge in cardiology, both as a physician and as a basic scientist. His invention of propranolol, the beta adrenergic receptor antagonist that revolutionized the medical management of angina pectoris, is considered to be one of the most important contributions to clinical medicine and pharmacology of the 20th century. His method of research, his discoveries about adrenergic pharmacology, and his clarification of the mechanisms of cardiac action are all strengths of his work. In 1988, he was awarded the Nobel Prize in Medicine. Sir James's conclusions and method of research have continued to influence work in clinical pharmacology and cardiovascular medicine. Thus, the development of propranolol runs parallel to most other great achievements in medicine: the genius of a few builds on the accomplishments of many, and the discovery influences thinking long after the breakthrough has occurred. Images PMID:9456487

  1. The role of a science story, activities, and dialogue modeled on Philosophy for Children in teaching basic science process skills to fifth graders

    NASA Astrophysics Data System (ADS)

    Ferreira, Louise Brandes Moura

    This study was an application of Philosophy for Children pedagogy to science education. It was designed to answer the question, What roles do a science story (Harry Discovers Science), multi-sensorial activities designed to accompany the story, and classroom dialogue associated with the story---all modeled on the Philosophy for Children curriculum---play in the learning processes of a class of fifth graders with regard to the basic science process skills of classification, observation, and inference? To answer the question, I collected qualitative data as I carried out a participatory study in which I taught science to fifth graders at an international, bilingual private religious school in Brasilia, Brazil for a period of one semester. Twenty-one (n = 21) children participated in the study, 10 females and 11 males, who came from a predominantly middle and upper class social background. Data were collected through student interviews, student class reflection sheets, written learning assessments, audiotapes of all class sessions, including whole-class and small-class group discussions, and a videotape of one class session. Some of the key findings were that the story, activities and dialogue facilitated the children's learning in a number of ways. The story modeled the performance of classification, observation and inference skills for the children as well as reflection on the meaning of inference. The majority of the students identified with the fictional characters, particularly regarding traits such as cleverness and inquisitiveness, and with the learning context of the story. The multi-sensorial activities helped children learn observation and inference skills as well as dialogue. Dialogue also helped children self-correct and build upon each other's ideas. Some students developed theories about how ideal dialogue should work. In spite of the inherent limitations of qualitative and teacher research studies, as well as the limitations of this particular study

  2. Human Health and the Biological Effects of Tritium in Drinking Water: Prudent Policy Through Science - Addressing the ODWAC New Recommendation.

    PubMed

    Dingwall, S; Mills, C E; Phan, N; Taylor, K; Boreham, D R

    2011-02-22

    Tritium is a radioactive form of hydrogen and is a by-product of energy production in Canadian Deuterium Uranium (CANDU) reactors. The release of this radioisotope into the environment is carefully managed at CANDU facilities in order to minimize radiation exposure to the public. However, under some circumstances, small accidental releases to the environment can occur. The radiation doses to humans and non-human biota from these releases are low and orders of magnitude less than doses received from naturally occurring radioisotopes or from manmade activities, such as medical imaging and air travel. There is however a renewed interest in the biological consequences of low dose tritium exposures and a new limit for tritium levels in Ontario drinking water has been proposed. The Ontario Drinking Water Advisory Council (ODWAC) issued a formal report in May 2009 in response to a request by the Minister of the Environment, concluding that the Ontario Drinking Water Quality Standard for tritium should be revised from the current 7,000 Bq/L level to a new, lower 20 Bq/L level. In response to this recommendation, an international scientific symposium was held at McMaster University to address the issues surrounding this change in direction and the validity of a new policy. Scientists, regulators, government officials, and industrial stakeholders were present to discuss the potential health risks associated with low level radiation exposure from tritium. The regulatory, economic, and social implications of the new proposed limit were also considered.The new recommendation assumed a linear-no-threshold model to calculate carcinogenic risk associated with tritium exposure, and considered tritium as a non-threshold chemical carcinogen. Both of these assumptions are highly controversial given that recent research suggests that low dose exposures have thresholds below which there are no observable detrimental effects. Furthermore, mutagenic and carcinogenic risk calculated from

  3. ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.

    PubMed

    Arteaga, Carlos L; Engelman, Jeffrey A

    2014-03-17

    ERBB receptors were linked to human cancer pathogenesis approximately three decades ago. Biomedical investigators have since developed substantial understanding of the biology underlying the dependence of cancers on aberrant ERBB receptor signaling. An array of cancer-associated genetic alterations in ERBB receptors has also been identified. These findings have led to the discovery and development of mechanism-based therapies targeting ERBB receptors that have improved outcome for many cancer patients. In this Perspective, we discuss current paradigms of targeting ERBB receptors with cancer therapeutics and our understanding of mechanisms of action and resistance to these drugs. As current strategies still have limitations, we also discuss challenges and opportunities that lie ahead as basic scientists and clinical investigators work toward more breakthroughs.

  4. An expanding universe of noncoding RNAs between the poles of basic science and clinical investigations.

    PubMed

    Weil, Patrick P; Hensel, Kai O; Weber, David; Postberg, Jan

    2016-03-01

    The Keystone Symposium 'MicroRNAs and Noncoding RNAs in Cancer', Keystone, CO, USA, 7-12 June 2015 Since the discovery of RNAi, great efforts have been undertaken to unleash the potential biomedical applicability of small noncoding RNAs, mainly miRNAs, involving their use as biomarkers for personalized diagnostics or their usability as active agents or therapy targets. The research's focus on the noncoding RNA world is now slowly moving from a phase of basic discoveries into a new phase, where every single molecule out of many hundreds of cataloged noncoding RNAs becomes dissected in order to investigate these molecules' biomedical relevance. In addition, RNA classes neglected before, such as long noncoding RNAs or circular RNAs attract more attention. Numerous timely results and hypotheses were presented at the 2015 Keystone Symposium 'MicroRNAs and Noncoding RNAs in Cancer'.

  5. Beyond the data - Topics that resonate with students when communicating basic climate science in a Geoscience course

    NASA Astrophysics Data System (ADS)

    Bouvier-Brown, N. C.

    2013-12-01

    Instructors will undoubtedly want to cover basic climate change science in undergraduate geosciences courses. When instructors have limited time in a course, they would like to know what topics will not only provide factual climate data, but also resonate with students. Instructors want to bring a variety of information to the classroom, but even if time allows, this can sometimes become too overwhelming and lead to diminishing returns. This study is based on a series of surveys conducted in an upper-division Air Pollution/Atmospheric Chemistry course at Loyola Marymount University to assess students' opinions on climate change, how these opinions change throughout the semester, and what teaching resources/topics were most effective in catalyzing those changes. Data will be presented to show that not only opinions, but also the level of student confidence in this politically-sensitive topic, shifted by the end of the semester. At the end of the semester, students evaluated their level of agreement with how much each specific topic presented significantly contributed to their understanding that 1) the climate is indeed changing, and 2) humans have a large role in climate change. In general, students find the timeline of the link between greenhouse gases and temperature particularly compelling. Lastly, even in this physical science course students clearly gained an appreciation for the role of science in politics and social justice. Not only is this a tenant of liberal arts education, but it seems as if students find this interdisciplinary connection empowering.

  6. Beyond the data - Topics that resonate with students when communicating basic climate science in a Geoscience course

    NASA Astrophysics Data System (ADS)

    Byrne, J. M.; McDaniel, S.; Graham, J.; Hoggan, J. C.

    2011-12-01

    Instructors will undoubtedly want to cover basic climate change science in undergraduate geosciences courses. When instructors have limited time in a course, they would like to know what topics will not only provide factual climate data, but also resonate with students. Instructors want to bring a variety of information to the classroom, but even if time allows, this can sometimes become too overwhelming and lead to diminishing returns. This study is based on a series of surveys conducted in an upper-division Air Pollution/Atmospheric Chemistry course at Loyola Marymount University to assess students' opinions on climate change, how these opinions change throughout the semester, and what teaching resources/topics were most effective in catalyzing those changes. Data will be presented to show that not only opinions, but also the level of student confidence in this politically-sensitive topic, shifted by the end of the semester. At the end of the semester, students evaluated their level of agreement with how much each specific topic presented significantly contributed to their understanding that 1) the climate is indeed changing, and 2) humans have a large role in climate change. In general, students find the timeline of the link between greenhouse gases and temperature particularly compelling. Lastly, even in this physical science course students clearly gained an appreciation for the role of science in politics and social justice. Not only is this a tenant of liberal arts education, but it seems as if students find this interdisciplinary connection empowering.

  7. Beyond the Flipped Classroom: A Highly Interactive Cloud-Classroom (HIC) Embedded into Basic Materials Science Courses

    NASA Astrophysics Data System (ADS)

    Liou, Wei-Kai; Bhagat, Kaushal Kumar; Chang, Chun-Yen

    2016-06-01

    The present study compares the highly interactive cloud-classroom (HIC) system with traditional methods of teaching materials science that utilize crystal structure picture or real crystal structure model, in order to examine its learning effectiveness across three dimensions: knowledge, comprehension and application. The aim of this study was to evaluate the (HIC) system, which incorporates augmented reality, virtual reality and cloud-classroom to teach basic materials science courses. The study followed a pretest-posttest quasi-experimental research design. A total of 92 students (aged 19-20 years), in a second-year undergraduate program, participated in this 18-week-long experiment. The students were divided into an experimental group and a control group. The experimental group (36 males and 10 females) was instructed utilizing the HIC system, while the control group (34 males and 12 females) was led through traditional teaching methods. Pretest, posttest, and delayed posttest scores were evaluated by multivariate analysis of covariance. The results indicated that participants in the experimental group who used the HIC system outperformed the control group, in the both posttest and delayed posttest, across three learning dimensions. Based on these results, the HIC system is recommended to be incorporated in formal materials science learning settings.

  8. Exploring Ivorian perspectives on the effectiveness of the current Ivorian science curriculum in addressing issues related to HIV/AIDS

    NASA Astrophysics Data System (ADS)

    Ado, Gustave Firmin

    School-based HIV/AIDS science education has the potential to impact students when integrated into the science curriculum. However, this mixed method study shows that school-based HIV/AIDS science education is often not infused into career subjects such as science education but integrated into civics education and taught by teachers who lack the skills, knowledge, and the training in the delivery of effective school HIV/AIDS education. Since science is where biological events take place, it is suggested that HIV/AIDS science merits being taught in the science education classroom. This study took place in nine public middle schools within two school districts in Abidjan, Ivory Coast, one major urban city in the southern region. The study utilized triangulation of multiple data sources---both qualitative and quantitative. To substantiate the claims made in this study, a range of qualitative methods such as field notes and individual interviews with 39 teachers, 63 sixth grade students, 8 school administrators, and 20 community elders were used. For the quantitative portion 140 teachers and 3510 sixth grade students were surveyed. The findings from the study prioritize science education that includes HIV/AIDS science education for all, with emphasis on HIV/AIDS prevention in Ivory Coast. The factors that influence the implementation of HIV/AIDS curricula within the Ivorian sixth grade classrooms are discussed. Interview and survey data from students, teachers, school administrators, and community elders indicate that in the Ivorian school setting, "gerontocratic" cultural influences, religious beliefs, personal cultural beliefs, and time spent toward the discourse on HIV/AIDS have led to HIV/AIDS education that is often insufficient to change either misconceptions about HIV/AIDS or risky practices. It was also found that approaches to teaching HIV/AIDS does not connect with youth cultures. By reframing and integrating current HIV/AIDS curricula into the science

  9. Contextualizing the relevance of basic sciences: small-group simulation with debrief for first- and second-year medical students in an integrated curriculum

    PubMed Central

    Ginzburg, Samara B; Brenner, Judith; Cassara, Michael; Kwiatkowski, Thomas; Willey, Joanne M

    2017-01-01

    Aim There has been a call for increased integration of basic and clinical sciences during preclinical years of undergraduate medical education. Despite the recognition that clinical simulation is an effective pedagogical tool, little has been reported on its use to demonstrate the relevance of basic science principles to the practice of clinical medicine. We hypothesized that simulation with an integrated science and clinical debrief used with early learners would illustrate the importance of basic science principles in clinical diagnosis and management of patients. Methods Small groups of first- and second-year medical students were engaged in a high-fidelity simulation followed by a comprehensive debrief facilitated by a basic scientist and clinician. Surveys including anchored and open-ended questions were distributed at the conclusion of each experience. Results The majority of the students agreed that simulation followed by an integrated debrief illustrated the clinical relevance of basic sciences (mean ± standard deviation: 93.8% ± 2.9% of first-year medical students; 96.7% ± 3.5% of second-year medical students) and its importance in patient care (92.8% of first-year medical students; 90.4% of second-year medical students). In a thematic analysis of open-ended responses, students felt that these experiences provided opportunities for direct application of scientific knowledge to diagnosis and treatment, improving student knowledge, simulating real-world experience, and developing clinical reasoning, all of which specifically helped them understand the clinical relevance of basic sciences. Conclusion Small-group simulation followed by a debrief that integrates basic and clinical sciences is an effective means of demonstrating the relationship between scientific fundamentals and patient care for early learners. As more medical schools embrace integrated curricula and seek opportunities for integration, our model is a novel approach that can be utilized

  10. A Research Agenda for Malaria Eradication: Basic Science and Enabling Technologies

    PubMed Central

    2011-01-01

    Today's malaria control efforts are limited by our incomplete understanding of the biology of Plasmodium and of the complex relationships between human populations and the multiple species of mosquito and parasite. Research priorities include the development of in vitro culture systems for the complete life cycle of P. falciparum and P. vivax and the development of an appropriate liver culture system to study hepatic stages. In addition, genetic technologies for the manipulation of Plasmodium need to be improved, the entire parasite metabolome needs to be characterized to identify new druggable targets, and improved information systems for monitoring the changes in epidemiology, pathology, and host-parasite-vector interactions as a result of intensified control need to be established to bridge the gap between bench, preclinical, clinical, and population-based sciences. PMID:21311584

  11. Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)

    PubMed Central

    Shanmugam, Ganesh; Ali, Imtiaz S

    2009-01-01

    Congestive heart failure as a consequence of ischemic heart disease is an increasing medical problem. Notwithstanding the huge advances in the medical and conventional surgical management of heart failure, eventual outcomes remain suboptimal. This 2 part article outlines the magnitude of the problem, the limitations of conventional therapies as they exist, and the use of newer procedures that directly address the restoration of ventricular pump function. The first part of the article deals with the pathology of different facets of the remodeling process, and the unique anatomy, geometry and flow dynamics as they pertain to ventricular function in the normal as well as the failing heart. It then details the limitations of conventional therapy, thereby laying the basis for the need and evolution of newer surgical procedures and ends with the selection of patients for ventricular restoration procedures and the pitfalls in the choice of patients for such newer techniques. PMID:21037851

  12. Opportunities for Early Intervention Based on Theory, Basic Neuroscience, and Clinical Science

    PubMed Central

    2010-01-01

    Therapeutic approaches in the pediatric population have generally been less aggressive than those implemented for younger and older adults. Several factors contribute to this, starting with the challenge of engaging infants in the “goal” of therapy, their resistance to initiating behaviors that are uncomfortable or fatiguing, the desire to make therapy as functionally relevant as possible when many functional skills have yet to emerge, and residual history of outdated theoretical concepts. On the practical side of who will pay for this more aggressive approach, there is limited empirical evidence based on randomized controlled trials to convince third-party payers to fund more extensive services. This article outlines a theoretical perspective prominent in developmental science that argues not only for the importance of frequent bouts of functionally relevant activity on the self-organization of behavioral patterns, but also for the impact that should be expected from the use of rigorous interventions on underlying subsystems, such as neural organization, that support these outcomes. In order to propose some future opportunities for clinical research and application, examples from recent activity-based clinical studies are presented, along with theoretical principles, neuroscience, and other tissue science data concerning mechanisms that contribute to behavioral changes. One such opportunity is to increase the structured engagement of caregivers, guided by therapists, in administering well-defined activity intervention programs focused on the development of specific functional skills. Such an approach may be one of the few financially feasible options for generating sufficient therapy that adheres to principles for optimizing development of neuromotor control. PMID:20966210

  13. Can Clinical Scenario Videos Improve Dental Students' Perceptions of the Basic Sciences and Ability to Apply Content Knowledge?

    PubMed

    Miller, Cynthia Jayne; Metz, Michael James

    2015-12-01

    Dental students often have difficulty understanding the importance of basic science classes, such as physiology, for their future careers. To help alleviate this problem, the aim of this study was to create and evaluate a series of video modules using simulated patients and custom-designed animations that showcase medical emergencies in the dental practice. First-year students in a dental physiology course formatively assessed their knowledge using embedded questions in each of the three videos; 108 to 114 of the total 120 first-year students answered the questions, for a 90-95% response rate. These responses indicated that while the students could initially recognize the cause of the medical emergency, they had difficulty in applying their knowledge of physiology to the scenario. In two of the three videos, students drastically improved their ability to answer high-level clinical questions at the conclusion of the video. Additionally, when compared to the previous year of the course, there was a significant improvement in unit exam scores on clinically related questions (6.2% increase). Surveys were administered to the first-year students who participated in the video modules and fourth-year students who had completed the course prior to implementation of any clinical material. The response rate for the first-year students was 96% (115/120) and for the fourth-year students was 57% (68/120). The first-year students indicated a more positive perception of the physiology course and its importance for success on board examinations and their dental career than the fourth-year students. The students perceived that the most positive aspects of the modules were the clear applications of physiology to real-life dental situations, the interactive nature of the videos, and the improved student comprehension of course concepts. These results suggest that online modules may be used successfully to improve students' perceptions of the basic sciences and enhance their ability to

  14. Getting to Know and Address Your State Science Standards to Connect Classroom Instruction and Field Trips During IYA

    NASA Astrophysics Data System (ADS)

    Bednarski, M.; Larsen, K.

    2008-11-01

    Astronomy activities often pose problems for in-service teachers, especially at the elementary level, as many do not have a solid content background. Often astronomy instruction revolves around reading and answering questions. This is not an effective way to work with abstract concepts or engage students, and also fails to meet the standards of inquiry-based instruction recommended by the National Science Teachers Association and national and state standards. Science museums and planetariums bring unique and exciting perspectives to astronomy education. However, bringing students to the museum can sometimes be perceived as only a ``cool field trip.'' With mounting pressure for teachers to teach to the new standardized tests demanded by No Child Left Behind, and shrinking school budgets, field trips are rapidly becoming an endangered species. Coordinating museum, science center, and planetarium offerings with national and state science standards can renew interest in (and perceived relevance of) field trips. Therefore, university faculty, in-service teachers, and museum/planetarium staff can form successful partnerships which can both improve student learning and increase attendance at informal education science events and facilities. This workshop will first briefly introduce participants to national and representative state standards as well as research on in-service teachers' astronomy content knowledge and the educational value of field trips. For the majority of the workshop, participants will engage in the actual steps of coordinating, planning, and writing inquiry-based astronomy curriculum embedded performance tasks that collectively meet the learning needs of students in elementary, middle, or high school.

  15. Ascending monoaminergic systems alterations in Alzheimer's disease. translating basic science into clinical care.

    PubMed

    Trillo, Ludwig; Das, Devsmita; Hsieh, Wayne; Medina, Brian; Moghadam, Sarah; Lin, Bill; Dang, Van; Sanchez, Martha Millan; De Miguel, Zurine; Ashford, J Wesson; Salehi, Ahmad

    2013-09-01

    Extensive neuropathological studies have established a compelling link between abnormalities in structure and function of subcortical monoaminergic (MA-ergic) systems and the pathophysiology of Alzheimer's disease (AD). The main cell populations of these systems including the locus coeruleus, the raphe nuclei, and the tuberomamillary nucleus undergo significant degeneration in AD, thereby depriving the hippocampal and cortical neurons from their critical modulatory influence. These studies have been complemented by genome wide association studies linking polymorphisms in key genes involved in the MA-ergic systems and particular behavioral abnormalities in AD. Importantly, several recent studies have shown that improvement of the MA-ergic systems can both restore cognitive function and reduce AD-related pathology in animal models of neurodegeneration. This review aims to explore the link between abnormalities in the MA-ergic systems and AD symptomatology as well as the therapeutic strategies targeting these systems. Furthermore, we will examine possible mechanisms behind basic vulnerability of MA-ergic neurons in AD.

  16. Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications--a position report.

    PubMed

    Barratt, Christopher L R; Aitken, R John; Björndahl, Lars; Carrell, Douglas T; de Boer, Peter; Kvist, Ulrik; Lewis, Sheena E M; Perreault, Sally D; Perry, Melissa J; Ramos, Liliana; Robaire, Bernard; Ward, Steven; Zini, Armand

    2010-04-01

    This article reports the results of the most recent in a series of EHSRE workshops designed to synthesize the current state of the field in Andrology and provide recommendations for future work (for details see Appendix). Its focus is on methods for detecting sperm DNA damage and potential application of new knowledge about sperm chromatin organization, vulnerability and repair to improve the diagnosis and treatment of clinical infertility associated with that damage. Equally important is the use and reliability of these tests to identify the extent to which environmental contaminants or pharmaceutical agents may contribute to the incidence of sperm DNA damage and male fertility problems. A working group (for workshop details, see Appendix) under the auspices of ESHRE met in May 2009 to assess the current knowledgebase and suggest future basic and clinical research directions. This document presents a synthesis of the working group's understanding of the recent literature and collective discussions on the current state of knowledge of sperm chromatin structure and function during fertilization. It highlights the biological, assay and clinical uncertainties that require further research and ends with a series of 5 key recommendations.

  17. The Tarsal Bone Test: A Basic Test of Health Sciences Students' Knowledge of Lower Limb Anatomy

    PubMed Central

    Castillo-López, José Manuel; Díaz-Mancha, Juan Antonio; Heredia-Rizo, Alberto Marcos; Fernández-Seguín, Lourdes María; Polo-Padillo, Juan; Domínguez-Maldonado, Gabriel; Munuera, Pedro V.

    2014-01-01

    Objectives. The aim of the present study was to design an easy-to-use tool, the tarsal bone test (TBT), to provide a snapshot of podiatry students' basic anatomical knowledge of the bones of the lower limb. Methods. The study included 254 podiatry students from three different universities, 145 of them were first-year students and 109 were in their fourth and final years. The TBT was administered without prior notice to the participants and was to be completed in 5 minutes. Results. The results show that 97.2% of the subjects (n = 247) correctly labelled all tarsal bones, while the other 2.8% (n = 7) incorrectly labelled at least one bone, that was either the cuboid (7 times) or the navicular (6 times). Although only one fourth-year student inaccurately identified one bone, no significant differences in the distribution of the correct and incorrect responses were found between first and fourth-year students. Conclusions. The TBT seems to be a straightforward and easy-to-apply instrument, and provides an objective view of the level of knowledge acquired at different stages of podiatry studies. PMID:25110712

  18. Advances in classification, basic mechanisms and clinical science in ankylosing spondylitis and axial spondyloarthritis.

    PubMed

    Robinson, P C; Benham, H

    2015-02-01

    The field of spondyloarthritis (SpA) has seen huge advances over the past 5 years. The classification of axial disease has been redefined by the axial SpA criteria that incorporate disease captured before radiographic damage is evident as well as established erosive sacroiliac joint disease. Our knowledge of genetics and basic immunological pathways has progressed significantly. In addition, revolutionary progress has been achieved with the availability of tumour necrosis factor inhibitors for treating patients with moderate to severe disease. In parallel, several of novel biomarkers have been identified that show significant promise for the future. Advances in magnetic resonance imaging have helped define positive disease. We have identified that T1 and short tau inversion recovery sequences are best for the diagnosis of axial SpA, and gadolinium contrast is not additive for diagnosis. Progress has been made in identifying potential agents and strategies that reduce radiographic progression. Several referral strategies aimed at appropriate identification of patients have been trialled and found to be effective. There is still substantial work ahead, but the advances of the last 5 years have made a huge and tangible difference at the clinical coalface, and we suggest that this trend will continue.

  19. Superconducting magnet performance for 28 GHz electron cyclotron resonance ion source developed at the Korea Basic Science Institute

    SciTech Connect

    Park, Jin Yong; Choi, Seyong; Lee, Byoung-Seob; Yoon, Jang-Hee; Ok, Jung-Woo; Shin, Chang Seouk; Won, Mi-Sook; Kim, Byoung Chul; Ahn, Jung Keun

    2014-02-15

    A superconducting magnet for use in an electron cyclotron resonance ion source was developed at the Korea Basic Science Institute. The superconducting magnet is comprised of three solenoids and a hexapole magnet. According to the design value, the solenoid magnets can generate a mirror field, resulting in axial magnetic fields of 3.6 T at the injection area and 2.2 T at the extraction region. A radial field strength of 2.1 T can also be achieved by hexapole magnet on the plasma chamber wall. NbTi superconducting wire was used in the winding process following appropriate techniques for magnet structure. The final assembly of the each magnet involved it being vertically inserted into the cryostat to cool down the temperature using liquid helium. The performance of each solenoid and hexapole magnet was separately verified experimentally. The construction of the superconducting coil, the entire magnet assembly for performance testing and experimental results are reported herein.

  20. United Nations Basic Space Science Initiative: 2010 Status Report on the International Space Weather Initiative

    NASA Astrophysics Data System (ADS)

    Gadimova, S.; Haubold, H. J.; Danov, D.; Georgieva, K.; Maeda, G.; Yumoto, K.; Davila, J. M.; Gopalswamy, N.

    2011-11-01

    The UNBSSI is a long-term effort for the development of astronomy and space science through regional and international cooperation in this field on a worldwide basis. A series of workshops on BSS was held from 1991 to 2004 (India 1991, Costa Rica and Colombia 1992, Nigeria 1993, Egypt 1994, Sri Lanka 1995, Germany 1996, Honduras 1997, Jordan 1999, France 2000, Mauritius 2001, Argentina 2002, and China 2004) Pursuant to resolutions of the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS) and its Scientific and Technical Subcommittee, since 2005, these workshops focused on the International Heliophysical Year 2007 (UAE 2005, India 2006, Japan 2007, Bulgaria 2008, Ro Korea 2009) Starting in 2010, the workshops focus on the International Space Weather Initiative (ISWI) as recommended in a three-year-work plan as part of the deliberations of UNCOPUOS (www.iswi-secretariat.org/). Workshops on the ISWI have been scheduled to be hosted by Egypt in 2010 for Western Asia, Nigeria in 2011 for Africa, and Ecuador in 2012 for Latin America and the Caribbean. Currently, fourteen IHY/ISWI instrument arrays with more than five hundred instruments are operational in ninety countries.

  1. Brain-Machine Interfaces: From Basic Science to Neuroprostheses and Neurorehabilitation.

    PubMed

    Lebedev, Mikhail A; Nicolelis, Miguel A L

    2017-04-01

    Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from neurophysiology, computer science, and engineering in an effort to establish real-time bidirectional links between living brains and artificial actuators. Although theoretical propositions and some proof of concept experiments on directly linking the brains with machines date back to the early 1960s, BMI research only took off in earnest at the end of the 1990s, when this approach became intimately linked to new neurophysiological methods for sampling large-scale brain activity. The classic goals of BMIs are 1) to unveil and utilize principles of operation and plastic properties of the distributed and dynamic circuits of the brain and 2) to create new therapies to restore mobility and sensations to severely disabled patients. Over the past decade, a wide range of BMI applications have emerged, which considerably expanded these original goals. BMI studies have shown neural control over the movements of robotic and virtual actuators that enact both upper and lower limb functions. Furthermore, BMIs have also incorporated ways to deliver sensory feedback, generated from external actuators, back to the brain. BMI research has been at the forefront of many neurophysiological discoveries, including the demonstration that, through continuous use, artificial tools can be assimilated by the primate brain's body schema. Work on BMIs has also led to the introduction of novel neurorehabilitation strategies. As a result of these efforts, long-term continuous BMI use has been recently implicated with the induction of partial neurological recovery in spinal cord injury patients.

  2. Cell based therapies for ischemic stroke: From basic science to bedside

    PubMed Central

    Liu, Xinfeng; Ye, Ruidong; Yan, Tao; Yu, Shan Ping; Wei, Ling; Xu, Gelin; Fan, Xinying; Jiang, Yongjun; Stetler, R. Anne; Liu, George; Chen, Jieli

    2014-01-01

    Cell therapy is emerging as a viable therapy to restore neurological function after stroke. Many types of stem/progenitor cells from different sources have been explored for their feasibility and efficacy for the treatment of stroke. Transplanted cells not only have the potential to replace the lost circuitry, but also produce growth and trophic factors, or stimulate the release of such factors from host brain cells, thereby enhancing endogenous brain repair processes. Although stem/progenitor cells have shown a promising role in ischemic stroke in experimental studies as well as initial clinical pilot studies, cellular therapy is still at an early stage in humans. Many critical issues need to be addressed including the therapeutic time window, cell type selection, delivery route, and in vivo monitoring of their migration pattern. This review attempts to provide a comprehensive synopsis of preclinical evidence and clinical experience of various donor cell types, their restorative mechanisms, delivery routes, imaging strategies, future prospects and challenges for translating cell therapies as a neurorestorative regimen in clinical applications. PMID:24333397

  3. Study of the impacts of patient-educators on the course of basic sciences in dental studies.

    PubMed

    Renard, E; Alliot-Licht, B; Gross, O; Roger-Leroi, V; Marchand, C

    2015-02-01

    Ever since 2006, Nantes University dental educators have started organising lectures led by the mother of a young patient suffering from ectodermic dysplasia (patient-educator) to help second-year students to better understand how important it is for their future dental work to better understand basic sciences. In this study, we have analysed this training experience on students' motivation. For this purpose, students were asked to complete questionnaires 10 days after the patient-educator's lecture (early assessment; n = 193) and 4 years later, during the last year of their dental studies (delayed assessment; n = 47). Moreover, 3 years after the first lecture, we analysed the ability of students to diagnose a mother carrying the ectodermic dysplasia genetic disorder, using a case-based learning exercise with a patient showing dental features similar to those exposed by the patient-educator (measure of knowledge; n = 42). Ten days after the lecture, the early assessment shows that all the students were interested in the lecture and 59% of the students declared being motivated to find out more about genetics whilst 54% declared the same thing about embryology courses. Moreover, 4 years later, 67% of the students remembered the patient-educator's lecture a little or very well. Three years after the course, 83% of the students diagnosed ectodermal dysplasia whilst studying the case-based example that listed typical dental phenotypes. In conclusion, this study shows that this original educational approach enhances dental students' motivation in learning basic sciences and that patient-educators could offer many benefits for students and patients.

  4. MODEL EVALUATION SCIENCE TO MEET TODAY'S QUALITY ASSURANCE REQUIREMENTS FOR REGULATORY USE: ADDRESSING UNCERTAINTY, SENSITIVITY, AND PARAMETERIZATION

    EPA Science Inventory

    The EPA/ORD National Exposure Research Lab's (NERL) UA/SA/PE research program addresses both tactical and strategic needs in direct support of ORD's client base. The design represents an integrated approach in achieving the highest levels of quality assurance in environmental de...

  5. MEETING IN TUCSON: MODEL EVALUATION SCIENCE TO MEET TODAY'S QUALITY ASSURANCE REQUIREMENTS FOR REGULATORY USE: ADDRESSING UNCERTAINTY, SENSITIVITY, AND PARAMETERIZATION

    EPA Science Inventory

    The EPA/ORD National Exposure Research Lab's (NERL) UA/SA/PE research program addresses both tactical and strategic needs in direct support of ORD's client base. The design represents an integrated approach in achieving the highest levels of quality assurance in environmental dec...

  6. Getting to Know and Address Your State Science Standards to Connect Classroom Instruction and Field Trips During IYA

    NASA Astrophysics Data System (ADS)

    Bednarski, Marsha; Larsen, K.

    2008-05-01

    Astronomy activities often pose problems for in-service teachers, especially at the elementary level, as many do not have a solid content background. Often astronomy instruction revolves around reading and answering questions. This is not an effective way to work with abstract concepts or engage students, and also fails to meet the standards of inquiry-based instruction recommended by the National Science Teachers Association and national and state standards. Science museums and planetariums bring unique and exciting perspectives to astronomy education. However, bringing students to the museum can sometimes be perceived as only a "cool field trip.” With mounting pressure for teachers to teach to the new standardized tests demanded by No Child Left Behind, and shrinking school budgets, field trips are rapidly becoming an endangered species. Coordinating museum, science center, and planetarium offerings with national and state science standards can renew interest in (and perceived relevance of) field trips. Therefore, university faculty, in-service teachers, and museum/planetarium staff can form successful partnerships which can both improve student learning and increase attendance at informal education science events and facilities. This workshop will first briefly introduce participants to national and representative state standards as well as research on in-service teachers’ astronomy content knowledge and the educational value of field trips. For the majority of the workshop, participants will engage in the actual steps of coordinating, planning, and writing inquiry-based astronomy curriculum embedded performance tasks that collectively meet the learning needs of students in elementary, middle, or high school. Participants are encouraged to bring a copy of their own state standards (available on their state's Department of Education website) for their preferred target age group.

  7. Addressing the Professional Preparation of Future Science Teachers To Teach Hands-On Science: A Pilot Study of a Laboratory Model.

    ERIC Educational Resources Information Center

    Sweeney, Aldrin E.; Paradis, Jeffrey A.

    2003-01-01

    Reports on a study of a pilot model of a laboratory training course that provides preservice secondary science teachers the opportunity to explore pedagogical possibilities and gain hands-on experience running a general chemistry lab. (DDR)

  8. Training the Translational Research Teams of the Future: UC Davis - HHMI Integrating Medicine into Basic Science Program

    PubMed Central

    Knowlton, Anne A.; Rainwater, Julie A.; Chiamvimonvat, Nipavan; Bonham, Ann C.; Robbins, John A.; Henderson, Stuart; Meyers, Frederick J.

    2013-01-01

    There is a need for successful models of how to recruit, train, and retain bench scientists at the earliest stages of their careers into translational research. One recent, promising model is the University of California Davis Howard Hughes Medical Institute Integrating Medicine into Basic Science (HHMI-IMBS) program, part of the HHMI Med into Grad initiative. This article outlines the HHMI-IMBS program’s logic, design, and curriculum that guide the goal of research that moves from bedside to bench. That is, a curriculum that provides graduate students with guided translational training, clinical exposure, team science competencies and mentors from diverse disciplines that will advance the students careers in clinical translational research and re-focusing of research to answer clinical dilemmas. The data indicate that this training program provides an effective, adaptable model for training future translational researchers. HHMI-IMBS students showed improved confidence in conducting translational research, greater interest in a future translational career, and higher levels of research productivity and collaborations than a comparable group of pre-doctoral students. PMID:24127920

  9. Training the translational research teams of the future: UC Davis-HHMI Integrating Medicine into Basic Science program.

    PubMed

    Knowlton, Anne A; Rainwater, Julie A; Chiamvimonvat, Nipavan; Bonham, Ann C; Robbins, John A; Henderson, Stuart; Meyers, Frederick J

    2013-10-01

    There is a need for successful models of how to recruit, train, and retain bench scientists at the earliest stages of their careers into translational research. One recent, promising model is the University of California Davis Howard Hughes Medical Institute Integrating Medicine into Basic Science (HHMI-IMBS) program, part of the HHMI Med into Grad initiative. This paper outlines the HHMI-IMBS program's logic, design, and curriculum that guide the goal of research that moves from bedside to bench. That is, a curriculum that provides graduate students with guided translational training, clinical exposure, team science competencies, and mentors from diverse disciplines that will advance the students careers in clinical translational research and re-focusing of research to answer clinical dilemmas. The authors have collected data on 55 HHMI-IMBS students to date. Many of these students are still completing their graduate work. In the current study the authors compare the initial two cohorts (15 students) with a group of 29 control students to examine the program success and outcomes. The data indicate that this training program provides an effective, adaptable model for training future translational researchers. HHMI-IMBS students showed improved confidence in conducting translational research, greater interest in a future translational career, and higher levels of research productivity and collaborations than a comparable group of predoctoral students.

  10. Welcome Address

    NASA Astrophysics Data System (ADS)

    Kiku, H.

    2014-12-01

    Ladies and Gentlemen, It is an honor for me to present my welcome address in the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3), as the president of Kanto Gakuin University. Particularly to those from abroad more than 17 countries, I am very grateful for your participation after long long trips from your home to Yokohama. On the behalf of the Kanto Gakuin University, we certainly welcome your visit to our university and stay in Yokohama. First I would like to introduce Kanto Gakuin University briefly. Kanto Gakuin University, which is called KGU, traces its roots back to the Yokohama Baptist Seminary founded in 1884 in Yamate, Yokohama. The seminary's founder was Albert Arnold Bennett, alumnus of Brown University, who came to Japan from the United States to establish a theological seminary for cultivating and training Japanese missionaries. Now KGU is a major member of the Kanto Gakuin School Corporation, which is composed of two kindergartens, two primary schools, two junior high schools, two senior high schools as well as KGU. In this university, we have eight faculties with graduate school including Humanities, Economics, Law, Sciences and Engineering, Architecture and Environmental Design, Human and Environmental Studies, Nursing, and Law School. Over eleven thousands students are currently learning in our university. By the way, my major is the geotechnical engineering, and I belong to the faculty of Sciences and Engineering in my university. Prof. T. Yamada, here, is my colleague in the same faculty. I know that the nuclear physics is one of the most active academic fields in the world. In fact, about half of the participants, namely, more than 50 scientists, come from abroad in this conference. Moreover, I know that the nuclear physics is related to not only the other fundamental physics such as the elementary particle physics and astrophysics but also chemistry, medical sciences, medical cares, and radiation metrology

  11. Preventing maternal and newborn deaths globally: using innovation and science to address challenges in implementing life-saving interventions.

    PubMed

    Peterson, Herbert B; Haidar, Joumana; Merialdi, Mario; Say, Lale; Gülmezoglu, A Metin; Fajans, Peter J; Mbizvo, Michael T; Ghaffar, Abdul; Tran, Nhan T; de Bernis, Luc; Laski, Laura; Freedman, Lynn P; Chopra, Mickey

    2012-09-01

    We have made important progress toward achieving Millennium Development Goals 4 and 5, with an estimated 47% decrease in maternal deaths and 28% decrease in newborn deaths globally since 1990. However, rapidly accelerating this progress is vital because far too many maternal and newborn deaths still occur each day. Fortunately, there are major initiatives underway to enhance global efforts in preventing these deaths, including the United Nations Secretary General's Global Strategy for Women's and Children's Health. We know why maternal and newborn deaths occur, where they occur, and how they occur, and we have highly effective interventions for preventing them. Nearly all (99%) maternal and newborn deaths occur in developing countries where the implementation of life-saving interventions has been a major challenge. Determining how best to meet this challenge will require more intensive interrelated efforts that include not only science-driven guidance on effective interventions, but also strategies and plans for implementing these interventions. Implementation science, defined as "the study of methods to promote the integration of research findings and evidence into healthcare policy and practice," will be key as will innovations in both technologies and implementation processes. We will need to develop conceptual and operational frameworks that link innovation and implementation science to implementation challenges for the Global Strategy. Likewise, we will need to expand and strengthen close cooperation between those with responsibilities for implementation and those with responsibilities for developing and supporting science-driven interventions. Realizing the potential for the Global Strategy will require commitment, coordination, collaboration, and communication-and the women and newborns we serve deserve no less.

  12. Trends of Students of the College of Basic Science towards Teaching the Course of Athletics and Health by Using Computer Technology in the World Islamic Sciences and Education University (WISE)

    ERIC Educational Resources Information Center

    Salameh, Ibrahim Abdul Ghani; Khawaldeh, Mohammad Falah Ali

    2014-01-01

    The Study aimed at identifying the trends of the students of basic sciences College in the World Islamic Sciences and Education University towards teaching health and sport course by using computer technology as a teaching method, and to identify also the impact of the variables of academic level and the gender on the students' trends. The study…

  13. Basic Education.

    ERIC Educational Resources Information Center

    Robinson, Virginia, Ed.

    1984-01-01

    This issue of "Basic Education" is devoted to the arts in education as a concern that should be addressed in a time of new priorities for the curriculum. Five articles and a book review are included. The opening article, "The State of the Arts in Education: Envisioning Active Participation By All" (Virginia Robinson),…

  14. Report of the Defense Science Board Subcommittee on Department of Defense Research Policy. Part 2. Further Analysis of Basic Research Policy

    DTIC Science & Technology

    1965-01-14

    POLICY „_-, < ^ZLECTE OCT 1 7 1988 Ha Part n. Further Analysis of Basic Research Policy 14 January 1965 Office of the Director of Defense Research... Research Policy Part II. Further Analysis of Basic Rssearch Policy, UNCLASSIFIED 12. PERSONAL AUTHOR(S) N/A 13a. TYPE OF REPORT Final 13b TIME COVERED...UNCLASSIFIED UNCLASSIFIED Report of the Defense Science Board Subcommittee on DEPARTMENT OF DEFENSE RESEARCH POLICY ThÄtocument contains information

  15. The Health Sciences and Technology Academy: an educational pipeline to address health care disparities in West Virginia.

    PubMed

    McKendall, Sherron Benson; Kasten, Kasandra; Hanks, Sara; Chester, Ann

    2014-01-01

    Health and educational disparities are national issues in the United States. Research has shown that health care professionals from underserved backgrounds are more likely than others to work in underserved areas. The Association of American Medical Colleges' Project 3000 by 2000, to increase the number of underrepresented minorities in medical schools, spurred the West Virginia School of Medicine to start the Health Sciences and Technology Academy (HSTA) in 1994 with the goal of supporting interested underrepresented high school students in pursuing college and health professions careers. The program was based on three beliefs: (1) if underrepresented high school students have potential and the desire to pursue a health professions career and are given the support, they can reach their goals, including obtaining a health professions degree; (2) underserved high school students are able to predict their own success if given the right resources; and (3) community engagement would be key to the program's success.In this Perspective, the authors describe the HSTA and its framework and philosophy, including the underlying theories and pedagogy from research in the fields of education and the behavioral/social sciences. They then offer evidence of the program's success, specifically for African American students, including graduates' high college-going rate and overwhelming intention to choose a health professions major. Finally, the authors describe the benefits of the HSTA's community partnerships, including providing mentors to students, adding legislative language providing tuition waivers and a budgetary line item devoted to the program, and securing program funding from outside sources.

  16. AIM: Attracting Women into Sciences.

    ERIC Educational Resources Information Center

    Hartman, Icial S.

    1995-01-01

    Addresses how to attract more college women into the sciences. Attracting Women into Sciences (AIM) is a comprehensive approach that begins with advising, advertising, and ambiguity. The advising process includes dispelling stereotypes and reviewing the options open to a female basic science major. Interaction, involvement and instruction, finding…

  17. Safe Shores and Resilient Transit Corridors: Using Science, Design, and Stakeholder Partnerships to Address Connecticut's Coastal Vulnerabilities

    NASA Astrophysics Data System (ADS)

    French, R. A.; Felson, A. J.; Kirmmse, E.; Hagemann, K.

    2015-12-01

    Connecticut's densely developed coastline is highly vulnerable to sea level rise and coastal storms. 95% of the state's entire population lives within 50 miles of the shore. Connecticut has more than $542 billion in insured assets in harms way, only Florida has a greater exposure. As part of the state of Connecticut Phase 1 application for the HUD National Disaster Resilience Competition, the Connecticut Institute for Resilience and Climate Adaptation (CIRCA) at the University of Connecticut undertook an assessment of coastal vulnerabilities, including the impacts of sea level rise on the frequency of flooding, socioeconomic factors, critical infrastructure, and housing using data collected from federal, state, and municipal sources. Connecticut's unique geology, characterized by a glaciated coastline with highly erodible former deltas and elevated ridgelines extending out to rocky headlands, became the basis of the climate adaptation approach. Together with a nine state agency workgroup, municipal and regional government, and non-profit and industry representatives, CIRCA and the Yale UED lab developed a long-term urban redevelopment solution of resilient access and egress corridors layered over ridgelines and resilient zones of transit oriented economic development linked to shoreline communities. This concept can be applied in both Connecticut's coastal cities like New Haven and its smaller towns. The process demonstrated the effective partnership between the universities and state agencies in bringing the science of flood modeling and mapping together with innovative design to create solutions for climate adaptation. However, it also revealed significant gaps in data availability to analyze the economic and social drivers for adopting different adaptation strategies. Furthermore, the accuracy of current flood mapping tools needs to be improved to predict future flooding at the municipal project scale. As Connecticut and other states move forward with resilience

  18. The Health Sciences and Technology Academy: An Educational Pipeline to Address Health Care Disparities in West Virginia

    PubMed Central

    McKendall, Sherron Benson; Kasten, Kasandra; Hanks, Sara; Chester, Ann

    2014-01-01

    Health and educational disparities are national issues in the United States. Research has shown that health care professionals from underserved backgrounds are more likely than others to work in underserved areas. The Association of American Medical Colleges’ Project 3000 by 2000, to increase the number of underrepresented minorities in medical schools, spurred the West Virginia School of Medicine to start the Health Sciences and Technology Academy (HSTA) in 1994 with the goal of supporting interested underrepresented high school students in pursuing college and health professions careers. The program was based on three beliefs: (1) if underrepresented high school students have potential and the desire to pursue a health professions career and are given the support, they can reach their goals, including obtaining a health professions degree; (2) underserved high school students are able to predict their own success if given the right resources; and (3) community engagement would be key to the program’s success. In this perspective, the authors describe the HSTA and its framework and philosophy, including the underlying theories and pedagogy from research in the fields of education and the behavioral/social sciences. They then offer evidence of the program’s success, specifically for African American students, including graduates’ high college-going rate and overwhelming intention to choose a health professions major. Finally, the authors describe the benefits of the HSTA’s community partnerships, including providing mentors to students, adding legislative language providing tuition waivers and a budgetary line item devoted to the program, and securing program funding from outside sources. PMID:24280836

  19. Opening Address

    NASA Astrophysics Data System (ADS)

    Yamada, T.

    2014-12-01

    related fields such as nuclear astrophysics, hypernuclear physics, hadron physics, and condensate matter physics so on. In fact, in this workshop, we also discuss the clustering aspects in the related fields. Thus, I expect in this workshop we can grasp the present status of the nuclear cluster physics and demonstrate its perspective in near future. This workshop is sponsored by several institutes and organizations. In particular, I would express our thanks for financial supports to Research Center for Nuclear Physics (RCNP), Osaka University, Center for Nuclear Study (CNS), University of Tokyo, Joint Institute for Computational Fundamental Science (JICFuS), and RIKEN Nishina Center for Accelerator- Based Science. They are cohosting this workshop. I would like also to appreciate my University, Kanto Gakuin University, who offers this nice place for one week and helps us to hold this workshop smoothly and conveniently. Today, the president of my University, Prof. Kuku, is here to present a welcome address. Thank you very much. Finally, with many of the participants leading this field both in theory and in experiment, we wish this workshop offers an opportunity to simulate communications not only during the workshop but also in the future. In addition, we hope you enjoy exploring city of Yokohama and the area around, as well as scientific discussions. Thank you very much for your attention.

  20. De-Marginalizing Science in the Early Elementary Classroom: Fostering Reform-Based Teacher Change through Professional Development, Accountability, and Addressing Teachers' Dilemmas

    NASA Astrophysics Data System (ADS)

    Berg, Alissa

    To develop a scientifically literate populace, students must acquire the motivation and foundational skills for success in science beginning at an early age. Unfortunately, science instruction is often marginalized in elementary schools for reasons including teachers' lack of confidence in teaching science and an overemphasis on literacy and mathematics. This study employed a case study design to examine the impact of teachers' dilemmas, career stage, coaching, and other forms of support on elementary teachers' abilities to teach science more often and in more reform-based ways. The conceptual lenses used to guide this dissertation include the theory related to teacher change, dilemmas, reform-oriented science teaching, and the professional learning continuum. Findings suggest that teachers' dilemmas must be addressed in order for them to move toward more reform-based science teaching practices. It was found that how teachers reconcile their dilemmas is due in part to their career stage, level of readiness, and access to a more knowledgeable other who can assist them in learning and enacting reform-based instruction. Moreover, the likelihood and extent of teacher change appears to be related to teachers recognizing a need to change their practice, developing the capacity to change, feeling accountable to change, and possessing the motivation to change. Implications for teacher educators, professional development providers, and curriculum developers are presented. It is argued that teachers require support the length of their career and, to be effective, this support must be personalized to their diverse and changing needs and responsive to the context in which they teach.

  1. Presidential address.

    PubMed

    Vohra, U

    1993-07-01

    The Secretary of India's Ministry of Health and Family Welfare serves as Chair of the Executive Council of the International Institute for Population Sciences in Bombay. She addressed its 35th convocation in 1993. Global population stands at 5.43 billion and increases by about 90 million people each year. 84 million of these new people are born in developing countries. India contributes 17 million new people annually. The annual population growth rate in India is about 2%. Its population size will probably surpass 1 billion by the 2000. High population growth rates are a leading obstacle to socioeconomic development in developing countries. Governments of many developing countries recognize this problem and have expanded their family planning programs to stabilize population growth. Asian countries that have done so and have completed the fertility transition include China, Japan, Singapore, South Korea, and Thailand. Burma, Malaysia, North Korea, Sri Lanka, and Vietnam have not yet completed the transition. Afghanistan, Bangladesh, Iran, Nepal, and Pakistan are half-way through the transition. High population growth rates put pressure on land by fragmenting finite land resources, increasing the number of landless laborers and unemployment, and by causing considerable rural-urban migration. All these factors bring about social stress and burden civic services. India has reduced its total fertility rate from 5.2 to 3.9 between 1971 and 1991. Some Indian states have already achieved replacement fertility. Considerable disparity in socioeconomic development exists among states and districts. For example, the states of Bihar, Madhya Pradesh, Rajasthan, and Uttar Pradesh have female literacy rates lower than 27%, while that for Kerala is 87%. Overall, infant mortality has fallen from 110 to 80 between 1981 and 1990. In Uttar Pradesh, it has fallen from 150 to 98, while it is at 17 in Kerala. India needs innovative approaches to increase contraceptive prevalence rates

  2. Conceiving "personality": Psychologist's challenges and basic fundamentals of the Transdisciplinary Philosophy-of-Science Paradigm for Research on Individuals.

    PubMed

    Uher, Jana

    2015-09-01

    Scientists exploring individuals, as such scientists are individuals themselves and thus not independent from their objects of research, encounter profound challenges; in particular, high risks for anthropo-, ethno- and ego-centric biases and various fallacies in reasoning. The Transdisciplinary Philosophy-of-Science Paradigm for Research on Individuals (TPS-Paradigm) aims to tackle these challenges by exploring and making explicit the philosophical presuppositions that are being made and the metatheories and methodologies that are used in the field. This article introduces basic fundamentals of the TPS-Paradigm including the epistemological principle of complementarity and metatheoretical concepts for exploring individuals as living organisms. Centrally, the TPS-Paradigm considers three metatheoretical properties (spatial location in relation to individuals' bodies, temporal extension, and physicality versus "non-physicality") that can be conceived in different forms for various kinds of phenomena explored in individuals (morphology, physiology, behaviour, the psyche, semiotic representations, artificially modified outer appearances and contexts). These properties, as they determine the phenomena's accessibility in everyday life and research, are used to elaborate philosophy-of-science foundations and to derive general methodological implications for the elementary problem of phenomenon-methodology matching and for scientific quantification of the various kinds of phenomena studied. On the basis of these foundations, the article explores the metatheories and methodologies that are used or needed to empirically study each given kind of phenomenon in individuals in general. Building on these general implications, the article derives special implications for exploring individuals' "personality", which the TPS-Paradigm conceives of as individual-specificity in all of the various kinds of phenomena studied in individuals.

  3. Shrinking Sea Ice, Thawing Permafrost, Bigger Storms, and Extremely Limited Data - Addressing Information Needs of Stakeholders in Western Alaska Through Participatory Decisions and Collaborative Science.

    NASA Astrophysics Data System (ADS)

    Murphy, K. A.; Reynolds, J.

    2015-12-01

    Communities, Tribes, and decision makers in coastal western Alaska are being impacted by declining sea ice, sea level rise, changing storm patterns and intensities, and increased rates of coastal erosion. Relative to their counterparts in the contiguous USA, their ability to plan for and respond to these changes is constrained by the region's generally meager or non-existent information base. Further, the information needs and logistic challenges are of a scale that perhaps can be addressed only through strong, strategic collaboration. Landscape Conservation Cooperatives (LCCs) are fundamentally about applied science and collaboration, especially collaborative decision making. The Western Alaska LCC has established a process of participatory decision making that brings together researchers, agency managers, local experts from Tribes and field specialists to identify and prioritize shared information needs; develop a course of action to address them by using the LCC's limited resources to catalyze engagement, overcome barriers to progress, and build momentum; then ensure products are delivered in a manner that meets decision makers' needs. We briefly review the LCC's activities & outcomes from the stages of (i) collaborative needs assessment (joint with the Alaska Climate Science Center and the Alaska Ocean Observing System), (ii) strategic science activities, and (iii) product refinement and delivery. We discuss lessons learned, in the context of our recent program focused on 'Changes in Coastal Storms and Their Impacts' and current collaborative efforts focused on delivery of Coastal Resiliency planning tools and results from applied science projects. Emphasis is given to the various key interactions between scientists and decision makers / managers that have been promoted by this process to ensure alignment of final products to decision maker needs.

  4. Learning Science, Learning about Science, Doing Science: Different Goals Demand Different Learning Methods

    ERIC Educational Resources Information Center

    Hodson, Derek

    2014-01-01

    This opinion piece paper urges teachers and teacher educators to draw careful distinctions among four basic learning goals: learning science, learning about science, doing science and learning to address socio-scientific issues. In elaboration, the author urges that careful attention is paid to the selection of teaching/learning methods that…

  5. Teaching Basic Science Environmentally.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1984-01-01

    Five activities on the concept of evaporation as a cooling process is presented. Activities include discovering which hand, the wet one or dry one, is cooler; reviving a wilted plant; measuring surface area of leaves; collecting water vapor from leaves; and finding out the cooling effect of trees. (ERB)

  6. Teaching Basic Science Environmentally.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1986-01-01

    Explains why earthworms are fascinating and important animals whose study should be expanded. Describes how to collect earthworms and their castings and how to demonstrate their tunneling activity. Stresses animal's uniqueness and how it is interrelated with other animals, plants, and non-living parts of the world. (NEC)

  7. Basic Ozone Layer Science

    EPA Pesticide Factsheets

    Learn about the ozone layer and how human activities deplete it. This page provides information on the chemical processes that lead to ozone layer depletion, and scientists' efforts to understand them.

  8. Teaching Basic Science Environmentally.

    ERIC Educational Resources Information Center

    Busch, Phylliss

    1987-01-01

    Discusses how, where, and when to capture indoor and outdoor insects for study: Grasshoppers, Cockroaches, Houseflies, Snowfleas, Stone Flies, Scorpian Flies, Crane Flies, Gypsy Moths, Tent Caterpillars, Bagworms, Praying Mantis, Oak Leaf Skeletonizers, Mourning Cloak Butterflies, Ladybird Beetles, Maple Leaf Cutters, Woolybears. Emphasizes…

  9. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease.

    PubMed

    Bernstein, Paul S; Li, Binxing; Vachali, Preejith P; Gorusupudi, Aruna; Shyam, Rajalekshmy; Henriksen, Bradley S; Nolan, John M

    2016-01-01

    The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green leafy vegetables and orange and yellow fruits and vegetables, while meso-zeaxanthin is rarely found in diet and is believed to be formed at the macula by metabolic transformations of ingested carotenoids. Epidemiological studies and large-scale clinical trials such as AREDS2 have brought attention to the potential ocular health and functional benefits of these three xanthophyll carotenoids consumed through the diet or supplements, but the basic science and clinical research underlying recommendations for nutritional interventions against age-related macular degeneration and other eye diseases are underappreciated by clinicians and vision researchers alike. In this review article, we first examine the chemistry, biochemistry, biophysics, and physiology of these yellow pigments that are specifically concentrated in the macula lutea through the means of high-affinity binding proteins and specialized transport and metabolic proteins where they play important roles as short-wavelength (blue) light-absorbers and localized, efficient antioxidants in a region at high risk for light-induced oxidative stress. Next, we turn to clinical evidence supporting functional benefits of these carotenoids in normal eyes and for their potential protective actions against ocular disease from infancy to old age.

  10. Citation Analysis of Iranian Journal of Basic Medical Sciences in ISI Web of Knowledge, Scopus, and Google Scholar

    PubMed Central

    Zarifmahmoudi, Leili; Kianifar, Hamid Reza; Sadeghi, Ramin

    2013-01-01

    Objective(s): Citation tracking is an important method to analyze the scientific impact of journal articles and can be done through Scopus (SC), Google Scholar (GS), or ISI web of knowledge (WOS). In the current study, we analyzed the citations to 2011-2012 articles of Iranian Journal of Basic Medical Sciences (IJBMS) in these three resources. Material and Methods: The relevant data from SC, GS, and WOS official websites. Total number of citations, their overlap and unique citations of these three recourses were evaluated. Results: WOS and SC covered 100% and GS covered 97% of the IJBMS items. Totally, 37 articles were cited at least once in one of the studied resources. Total number of citations were 20, 30, and 59 in WOS, SC, and GS respectively. Forty citations of GS, 6 citation of SC, and 2 citations of WOS were unique. Conclusion: Every scientific resource has its own inaccuracies in providing citation analysis information. Citation analysis studies are better to be done each year to correct any inaccuracy as soon as possible. IJBMS has gained considerable scientific attention from wide range of high impact journals and through citation tracking method; this visibility can be traced more thoroughly. PMID:24379959

  11. Lutein, Zeaxanthin, and meso-Zeaxanthin: The Basic and Clinical Science Underlying Carotenoid-based Nutritional Interventions against Ocular Disease

    PubMed Central

    Bernstein, Paul S.; Li, Binxing; Vachali, Preejith P.; Gorusupudi, Aruna; Shyam, Rajalekshmy; Henriksen, Bradley S.; Nolan, John M.

    2015-01-01

    The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green leafy vegetables and orange and yellow fruits and vegetables, while meso-zeaxanthin is rarely found in diet and is believed to be formed at the macula by metabolic transformations of ingested carotenoids. Epidemiological studies and large-scale clinical trials such as AREDS2 have brought attention to the potential ocular health and functional benefits of these three xanthophyll carotenoids consumed through the diet or supplements, but the basic science and clinical research underlying recommendations for nutritional interventions against age-related macular degeneration and other eye diseases are underappreciated by clinicians and vision researchers alike. In this review article, we first examine the chemistry, biophysics, and physiology of these yellow pigments that are specifically concentrated in the macula lutea through the means of high-affinity binding proteins and specialized transport and metabolic proteins where they play important roles as short-wavelength (blue) light-absorbers and localized, efficient antioxidants in a region at high risk for light-induced oxidative stress. Next, we turn to clinical evidence supporting functional benefits of these carotenoids in normal eyes and for their potential protective actions against ocular disease from infancy to old age. PMID:26541886

  12. Beginning to Teach Chemistry: How Personal and Academic Characteristics of Pre-Service Science Teachers Compare with Their Understandings of Basic Chemical Ideas

    ERIC Educational Resources Information Center

    Kind, Vanessa; Kind, Per Morten

    2011-01-01

    Around 150 pre-service science teachers (PSTs) participated in a study comparing academic and personal characteristics with their misconceptions about basic chemical ideas taught to 11-16-year-olds, such as particle theory, change of state, conservation of mass, chemical bonding, mole calculations, and combustion reactions. Data, collected by…

  13. Physics Education: Effect of Micro-Teaching Method Supported by Educational Technologies on Pre-Service Science Teachers' Misconceptions on Basic Astronomy Subjects

    ERIC Educational Resources Information Center

    Gurbuz, Fatih

    2016-01-01

    The purpose of this research study is to explore pre-service science teachers' misconceptions on basic astronomy subjects and to examine the effect of micro teaching method supported by educational technologies on correcting misconceptions. This study is an action research. Semi- structured interviews were used in the study as a data collection…

  14. Student Failures on First-Year Medical Basic Science Courses and the USMLE Step 1: A Retrospective Study over a 20-Year Period

    ERIC Educational Resources Information Center

    Burns, E. Robert; Garrett, Judy

    2015-01-01

    Correlates of achievement in the basic science years in medical school and on the Step 1 of the United States Medical Licensing Examination® (USMLE®), (Step 1) in relation to preadmission variables have been the subject of considerable study. Preadmissions variables such as the undergraduate grade point average (uGPA) and Medical College Admission…

  15. Use of the NBME Comprehensive Basic Science Examination as a Progress Test in the Preclerkship Curriculum of a New Medical School

    ERIC Educational Resources Information Center

    Johnson, Teresa R.; Khalil, Mohammed K.; Peppler, Richard D.; Davey, Diane D.; Kibble, Jonathan D.

    2014-01-01

    In the present study, we describe the innovative use of the National Board of Medical Examiners (NBME) Comprehensive Basic Science Examination (CBSE) as a progress test during the preclerkship medical curriculum. The main aim of this study was to provide external validation of internally developed multiple-choice assessments in a new medical…

  16. The Union County Hydrogeology Project: Addressing Potential Imbalances by Integrating Science and Communities in Northeastern New Mexico

    NASA Astrophysics Data System (ADS)

    Zeigler, K. E.; Podzemny, B.; Peacock, G.; Yuhas, A.; Williams, S.; Yuhas, E.

    2013-12-01

    The area around the town of Clayton, in northeastern New Mexico, was not a declared groundwater basin until September of 2005. In the years leading up to 2005, battles over groundwater use and attempts to stop drilling of additional water wells for irrigation and stock use led to multiple lawsuits in the community. Because there were no regulations in place and the geology of the area had not been studied in a hydrologic framework since the 1960s, there was no basic information for decisions to be made with regards to drilling new wells and use of groundwater, leading to the potential for severe imbalances in groundwater recharge versus usage in the region. In 2006, the Northeast Soil and Water Conservation District (NESWCD), based in Clayton, decided that a large scale hydrogeology project was needed to help develop community guidelines for groundwater development. In 2010, Zeigler Geologic Consulting and the NM Bureau of Geology partnered with the NESWCD to help develop this project. The Union County Hydrogeology Project (UCHP) is unique in that this project was initially undertaken by members of the community who developed a program of biannual static water level measurements in wells across the county. In addition, the project has support from the majority of land owners in Union County and the scientists working on the project have worked closely with local community leaders to integrate this large project into everyday activities. Community integration efforts include presenting data at the Annual Producers Meeting and at the county fair, as well as other regional conferences on water use and development. Previous assumptions were that the primary aquifers being utilized were the Tertiary Ogallala Formation and the Upper Cretaceous Dakota Group. However, evaluation of surface bedrock exposures and well cuttings from petroleum exploration wells drilled in eastern Union County demonstrate that the subsurface geology is more complex than might be expected. This

  17. Standardized Patient’s Views About their Role in the Teaching-Learning Process of Undergraduate Basic Science Medical Students

    PubMed Central

    Dwivedi, Neelam Rekha

    2016-01-01

    Introduction Standardized Patients (SPs) are widely used in medical education. SPs have a number of advantages but also have certain limitations. At the institution, SPs have been used since January 2013 for both teaching-learning and assessment during the basic science years of the undergraduate medical program. Aim The present study was conducted to investigate the perception of SPs about various aspects of the program and obtain suggestions for further improvement. Materials and Methods A Focus Group Discussion (FGD) was conducted with a group of five SPs during the second week of November 2015. Respondents were explained the aims and objectives of the study and invited to participate. Written informed consent was obtained. The FGD was conducted using a discussion guide and was audio recorded. Various aspects of the SP program at the institution were discussed. Motivation/s for joining the program and suggestions for further improvement were obtained. Transcripts were created after listening to the recordings and were read through multiple times. Similar responses were coded. Items with similar codes were grouped together into themes. Results Three respondents were female while two were male. The major advantage of SPs was their flexibility and ability to present a standardized response to the student. Students become familiar and comfortable with SPs. However, as a SP is simulating an illness s/he may not always be able to do complete justice to the role. The process used by SPs to prepare themselves to portray various diseases was highlighted. The use of SPs both during teaching-learning and assessment was also discussed. Some SPs are trained to provide feedback to students. Most SPs joined the program based on invitations from their friends who were already SPs. Challenges in recruiting SPs in a small island were discussed. Suggestions for further improvement were obtained. Conclusion The present study obtained the perception of SPs regarding various aspects

  18. Basic Research Needs for Solid-State Lighting. Report of the Basic Energy Sciences Workshop on Solid-State Lighting, May 22-24, 2006

    SciTech Connect

    Phillips, J. M.; Burrows, P. E.; Davis, R. F.; Simmons, J. A.; Malliaras, G. G.; So, F.; Misewich, J.A.; Nurmikko, A. V.; Smith, D. L.; Tsao, J. Y.; Kung, H.; Crawford, M. H.; Coltrin, M. E.; Fitzsimmons, T. J.; Kini, A.; Ashton, C.; Herndon, B.; Kitts, S.; Shapard, L.; Brittenham, P. W.; Vittitow, M. P.

    2006-05-24

    The workshop participants enthusiastically concluded that the time is ripe for new fundamental science to beget a revolution in lighting technology. SSL sources based on organic and inorganic materials have reached a level of efficiency where it is possible to envision their use for general illumination. The research areas articulated in this report are targeted to enable disruptive advances in SSL performance and realization of this dream. Broad penetration of SSL technology into the mass lighting market, accompanied by vast savings in energy usage, requires nothing less. These new ?good ideas? will be represented not by light bulbs, but by an entirely new lighting technology for the 21st century and a bright, energy-efficient future indeed.

  19. Pharmacy Education Reaction to Presentations on Bridging the Gap Between the Basic Sciences and Clinical Practice: Teaching, Research, and Service.

    ERIC Educational Resources Information Center

    Doluisio, James T.

    1980-01-01

    Issues in the conflict between clinical practice and basic research in pharmacy are reviewed: professional associations' role, curriculum needs and traditions, internal strains and diversity in the profession, computer use, scholarly work of faculty, using the medical profession as a model, and misperceptions of what clinical and basic sciences…

  20. EDITORIAL: Dialog on Science and Policy to Address the Climate Crisis to conclude the International Association of Research Universities Climate Congress, Copenhagen, Denmark Dialog on Science and Policy to Address the Climate Crisis to conclude the International Association of Research Universities Climate Congress, Copenhagen, Denmark

    NASA Astrophysics Data System (ADS)

    Baer, Paul; Kammen, Daniel M.

    2009-06-01

    This is not the usual Editor-in-Chief letter, namely one that focuses on the accomplishments of the journal—and for ERL they have been numerous this year—but a recognition of the critical time that we are now in when it comes to addressing not only global climate change, but also the dialog between science and politics. In recognition of the many 'tipping points' that we now confront—ideally some of them positive social moments—as well as the clear scientific conclusion that environmental tipping points are points of long-lasting disruption, this paper takes a different form than I might have otherwise written. While the scientific body of knowledge around global environmental change mounts, so too, do the hopeful signs that change can happen. The election of Barack Obama is unquestionably one such sign, witnessed by the exceptional interest that his story has brought not only to US politics, but also to global views of the potential of the United States, as well as to the potential role of science and investigation in addressing pressing issues. In light of these inter-related issues, reproduced here—largely due to the efforts of Paul Baer to transcribe a remarkable conversation—is a dialog not only on the science of global warming and the potential set of means to address this issue, but also on the interaction between research, science and the political process. The dialog itself is sufficiently important that I will dispense with the usual discussion of the exciting recognition that ERL has received with an ISI rating (a factor rapidly increasing), the high levels of downloads of our papers (for some articles over 5000 and counting), and the many news and scientific publications picking up ERL articles (in recent days alone Science, Environmental Science and Technology, and The Economist). This conversation was the concluding plenary session of the 10-12 March International Association of Research Universities (IARU) Conference on Climate Change

  1. Addressing healthcare.

    PubMed

    Daly, Rich

    2013-02-11

    Though President Barack Obama has rarely made healthcare references in his State of the Union addresses, health policy experts are hoping he changes that strategy this year. "The question is: Will he say anything? You would hope that he would, given that that was the major issue he started his presidency with," says Dr. James Weinstein, left, of the Dartmouth-Hitchcock health system.

  2. Harnessing the Use of Open Learning Exchange to Support Basic Education in Science and Mathematics in the Philippines

    ERIC Educational Resources Information Center

    Feliciano, Josephine S.; Mandapat, Louie Carl R.; Khan, Concepcion L.

    2013-01-01

    This paper presents the open learning initiatives of the Science Education Institute of the Department of Science and Technology to overcome certain barriers, such as enabling access, cost of replication, timely feedback, monitoring and continuous improvement of learning modules. Using an open-education model, like MIT's (Massachusetts Institute…

  3. Opportunities to Learn in School and at Home: How Can They Predict Students' Understanding of Basic Science Concepts and Principles?

    ERIC Educational Resources Information Center

    Wang, Su; Liu, Xiufeng; Zhao, Yandong

    2012-01-01

    As the breadth and depth of economic reforms increase in China, growing attention is being paid to equalities in opportunities to learn science by students of various backgrounds. In early 2009, the Chinese Ministry of Education and Ministry of Science and Technology jointly sponsored a national survey of urban eighth-grade students' science…

  4. AAAS News: Questions of Science Literacy Addressed by Rutherford/AAAS; 1982 Exhibit; Energy and Health to Be Discussed in Berkeley; Short Courses at Pacific Division, Annual Meeting.

    ERIC Educational Resources Information Center

    Science, 1981

    1981-01-01

    Presents the views of F. James Rutherford concerning the status of science education and his role as advisor on science education to the Board of Directors of the American Association for the Advancement of Science. (SK)

  5. Science Indicators: The 1985 Report.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC. National Science Board.

    This report provides basic information on patterns and trends of research and development (R&D) performance in the United States itself and in relation to other countries, as well as data on public attitudes toward science and technology. Major areas addressed in the report's eight chapters include (1) the international science and technology…

  6. Eleventh annual Warren K. Sinclair keynote address-science, radiation protection and NCRP: building on the past, looking to the future.

    PubMed

    Bushberg, Jerrold T

    2015-02-01

    The many reports and other authoritative documents developed and published by the National Council on Radiation Protection and Measurements (NCRP) have been of great service to the nation and the radiation protection community since its Congressional charter was signed into law 50 y ago. There will be a continuing need for NCRP to identify the principles upon which radiation protection is to be based and to provide guidance on best practices for the practical application of those principles for the many beneficial uses of radiation in society. The unique and invaluable resource that is NCRP is in large part due to the selfless dedication and numerous contributions of its Council and scientific committee members. The multidisciplinary composition of these leading experts and their collective input on complex questions provide a unique synergy that results in a comprehensive and well-balanced approach to addressing current and future radiation protection challenges. Subsequent articles in these proceedings covering a broad range of relevant topics will review sentinel accomplishments of the past as well as current work and future challenges that are in keeping with NCRP's mission to advance the science of radiation protection in the public interest.

  7. Perceptions of D.M.D. student readiness for basic science courses in the United States: can online review modules help?

    PubMed

    Miller, C J; Aiken, S A; Metz, M J

    2015-02-01

    There can be a disconnect between the level of content covered in undergraduate coursework and the expectations of professional-level faculty of their incoming students. Some basic science faculty members may assume that students have a good knowledge base in the material and neglect to appropriately review, whilst others may spend too much class time reviewing basic material. It was hypothesised that the replacement of introductory didactic physiology lectures with interactive online modules could improve student preparedness prior to lectures. These modules would also allow faculty members to analyse incoming student abilities and save valuable face-to-face class time for alternative teaching strategies. Results indicated that the performance levels of incoming U.S. students were poor (57% average on a pre-test), and students often under-predicted their abilities (by 13% on average). Faculty expectations varied greatly between the different content areas and did not appear to correlate with the actual student performance. Three review modules were created which produced a statistically significant increase in post-test scores (46% increase, P < 0.0001, n = 114-115). The positive results of this study suggest a need to incorporate online review units in the basic science dental school courses and revise introductory material tailored to students' strengths and needs.

  8. Teaching Future Teachers Basic Astronomy Concepts--Seasonal Changes--at a Time of Reform in Science Education

    ERIC Educational Resources Information Center

    Trumper, Ricardo

    2006-01-01

    Bearing in mind students' misconceptions about basic concepts in astronomy, the present study conducted a series of constructivist activities aimed at changing future elementary and junior high school teachers' conceptions about the cause of seasonal changes, and several characteristics of the Sun-Earth-Moon relative movements like Moon phases,…

  9. Inaugural address

    NASA Astrophysics Data System (ADS)

    Joshi, P. S.

    2014-03-01

    From jets to cosmos to cosmic censorship P S Joshi Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India E-mail: psj@tifr.res.in 1. Introduction At the outset, I should like to acknowledge that part of the title above, which tries to capture the main flavour of this meeting, and has been borrowed from one of the plenary talks at the conference. When we set out to make the programme for the conference, we thought of beginning with observations on the Universe, but then we certainly wanted to go further and address deeper questions, which were at the very foundations of our inquiry, and understanding on the nature and structure of the Universe. I believe, we succeeded to a good extent, and it is all here for you in the form of these Conference Proceedings, which have been aptly titled as 'Vishwa Mimansa', which could be possibly translated as 'Analysis of the Universe'! It is my great pleasure and privilege to welcome you all to the ICGC-2011 meeting at Goa. The International Conference on Gravitation and Cosmology (ICGC) series of meetings are being organized by the Indian Association for General Relativity and Gravitation (IAGRG), and the first such meeting was planned and conducted in Goa in 1987, with subsequent meetings taking place at a duration of about four years at various locations in India. So, it was thought appropriate to return to Goa to celebrate the 25 years of the ICGC meetings. The recollections from that first meeting have been recorded elsewhere here in these Proceedings. The research and teaching on gravitation and cosmology was initiated quite early in India, by V V Narlikar at the Banares Hindu University, and by N R Sen in Kolkata in the 1930s. In course of time, this activity grew and gained momentum, and in early 1969, at the felicitation held for the 60 years of V V Narlikar at a conference in Ahmedabad, P C Vaidya proposed the formation of the IAGRG society, with V V Narlikar being the first President. This

  10. Development of e-Learning Courses for Promoting Student's Global Competency-Basic Courses as a Guide to ESP Education in Advanced Science and Technology-

    NASA Astrophysics Data System (ADS)

    Nishikawa, Mikako; Nakajima, Mikio; Iwai, Chiharu; Ogasawara, Fumie; Kishino, Fumio; Fukui, Kiichi

    Osaka University has been chosen for the FY2005's “Selected Efforts of the Distinctive University Education Support Program (Gendai GP/Good Practice) ”by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) . The aim of this project is to improve English proficiency of undergraduate students with scientific backgrounds. Under this strategic fund, e-Learning course contents were developed for instructing basic, yet practical English for Biotechnology during FY2005. Throughout the project, e-Learning contents will be developed for five other selected subjects of science i.e., 1) biotechnology, 2) information technology, 3) nano-technology, 4) environmental technology and 5) robotics technology, for undergraduate students as guiding courses to ESP education in graduate (higher) level.

  11. Improving graduate education to support a branching career pipeline: recommendations based on a survey of doctoral students in the basic biomedical sciences.

    PubMed

    Fuhrmann, C N; Halme, D G; O'Sullivan, P S; Lindstaedt, B

    2011-01-01

    Today's doctoral programs continue to prepare students for a traditional academic career path despite the inadequate supply of research-focused faculty positions. We advocate for a broader doctoral curriculum that prepares trainees for a wide range of science-related career paths. In support of this argument, we describe data from our survey of doctoral students in the basic biomedical sciences at University of California, San Francisco (UCSF). Midway through graduate training, UCSF students are already considering a broad range of career options, with one-third intending to pursue a non-research career path. To better support this branching career pipeline, we recommend that national standards for training and mentoring include emphasis on career planning and professional skills development to ensure the success of PhD-level scientists as they contribute to a broadly defined global scientific enterprise.

  12. Improving Graduate Education to Support a Branching Career Pipeline: Recommendations Based on a Survey of Doctoral Students in the Basic Biomedical Sciences

    PubMed Central

    Fuhrmann, C. N.; Halme, D. G.; O’Sullivan, P. S.; Lindstaedt, B.

    2011-01-01

    Today's doctoral programs continue to prepare students for a traditional academic career path despite the inadequate supply of research-focused faculty positions. We advocate for a broader doctoral curriculum that prepares trainees for a wide range of science-related career paths. In support of this argument, we describe data from our survey of doctoral students in the basic biomedical sciences at University of California, San Francisco (UCSF). Midway through graduate training, UCSF students are already considering a broad range of career options, with one-third intending to pursue a non–research career path. To better support this branching career pipeline, we recommend that national standards for training and mentoring include emphasis on career planning and professional skills development to ensure the success of PhD-level scientists as they contribute to a broadly defined global scientific enterprise. PMID:21885820

  13. Convocation address.

    PubMed

    Kakodkar, A

    1999-07-01

    This convocation addressed by Dr. Anil Kakodkar focuses on the challenges faced by graduating students. In his speech, he emphasized the high level of excellence achieved by the industrial sector; however, he noted that there has been a loss of initiative in maximizing value addition, which was worsened by an increasing population pressure. In facing a stiff competition in the external and domestic markets, it is imperative to maximize value addition within the country in a competitive manner and capture the highest possible market share. To achieve this, high-quality human resources are central. Likewise, family planning programs should become more effective and direct available resources toward national advantage. To boost the domestic market, he suggests the need to search for strengths to achieve leadership position in those areas. First, an insight into the relationship between the lifestyles and the needs of our people and the natural resource endowment must be gained. Second, remodeling of the education system must be undertaken to prepare the people for adding the necessary innovative content in our value addition activities. Lastly, Dr. Kakodkar emphasizes the significance of developing a strong bond between parents and children to provide a sound foundation and allow the education system to grow upon it.

  14. Beyond the Flipped Classroom: A Highly Interactive Cloud-Classroom (HIC) Embedded into Basic Materials Science Courses

    ERIC Educational Resources Information Center

    Liou, Wei-Kai; Bhagat, Kaushal Kumar; Chang, Chun-Yen

    2016-01-01

    The present study compares the highly interactive cloud-classroom (HIC) system with traditional methods of teaching materials science that utilize crystal structure picture or real crystal structure model, in order to examine its learning effectiveness across three dimensions: knowledge, comprehension and application. The aim of this study was to…

  15. Resource Handbook--Matter and Energy. A Supplement to Basic Curriculum Guide--Science, Grades K-6.

    ERIC Educational Resources Information Center

    Starr, John W., 3rd., Ed.

    GRADES OR AGES: Grades K-6. SUBJECT MATTER: Science; matter and energy. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into the following six units: 1) Composition of Matter, with 27 concepts; 2) Light, with 20 concepts; 3) Heat, with 14 concepts; 4) Sound, with 12 concepts; 5) Electricity and Magnetism, with 17 concepts; and 6)…

  16. Program for Educational Mobility for Health Manpower (The Basic Sciences), June 12-August 25, 1970. Preliminary Report.

    ERIC Educational Resources Information Center

    Coordinating Council for Education in the Health Sciences for San Diego and Imperial Counties, CA.

    Community college administrators and faculty in the areas of anatomy, physiology, chemistry, physics, and microbiology attended an 11-day workshop to redefine, modify, and develop science concepts for a core curriculum in the allied health field. To achieve workshop objectives, the committee heard presentations by consultants, visited clinical…

  17. Final Report for the ZERT Project: Basic Science of Retention Issues, Risk Assessment & Measurement, Monitoring and Verification for Geologic Sequestration

    SciTech Connect

    Spangler, Lee; Cunningham, Alfred; Lageson, David; Melick, Jesse; Gardner, Mike; Dobeck, Laura; Repasky, Kevin; Shaw, Joseph; Bajura, Richard; McGrail, B Peter; Oldenburg, Curtis M; Wagoner, Jeff; Pawar, Rajesh

    2011-03-31

    ZERT has made major contributions to five main areas of sequestration science: improvement of computational tools; measurement and monitoring techniques to verify storage and track migration of CO{sub 2}; development of a comprehensive performance and risk assessment framework; fundamental geophysical, geochemical and hydrological investigations of CO{sub 2} storage; and investigate innovative, bio-based mitigation strategies.

  18. The Translational Science Training Program at NIH: Introducing Early Career Researchers to the Science and Operation of Translation of Basic Research to Medical Interventions

    ERIC Educational Resources Information Center

    Gilliland, C. Taylor; Sittampalam, G. Sitta; Wang, Philip Y.; Ryan, Philip E.

    2017-01-01

    Translational science is an emerging field that holds great promise to accelerate the development of novel medical interventions. As the field grows, so does the demand for highly trained biomedical scientists to fill the positions that are being created. Many graduate and postdoctorate training programs do not provide their trainees with…

  19. Reducing Inequities by Linking Basic Research and Political Action

    ERIC Educational Resources Information Center

    Mehan, Hugh

    2012-01-01

    In this comment, on Terri McCarty's Presidential Address, I focus on her dynamic approach to investigation that contributes to a vibrant and constructively critical exploration of the place of basic research, critical policy analysis, and activism in the anthropology of education and the social sciences more broadly.

  20. Muscles, Ligaments and Tendons Journal – Basic principles and recommendations in clinical and field Science Research: 2016 Update

    PubMed Central

    Padulo, Johnny; Oliva, Francesco; Frizziero, Antonio; Maffulli, Nicola

    2016-01-01

    Summary The proper design and implementation of a study as well as a balanced and well-supported evaluation and interpretation of its main findings are of crucial importance when reporting and disseminating research. Also accountability, funding acknowledgement and adequately declaring any conflict of interest play a major role in science. Since the Muscles, Ligaments and Tendons Journal (MLTJ) is committed to the highest scientific and ethical standards, we encourage all Authors to take into account and to comply, as much as possible, to the contents and issues discussed in this official editorial. This could be useful for improving the quality of the manuscripts, as well as to stimulate interest and debate and to promote constructive change, reflecting upon uses and misuses within our disciplines belonging to the field of “Clinical and Sport - Science Research”. PMID:27331026

  1. Student failures on first-year medical basic science courses and the USMLE step 1: a retrospective study over a 20-year period.

    PubMed

    Burns, E Robert; Garrett, Judy

    2015-01-01

    Correlates of achievement in the basic science years in medical school and on the Step 1 of the United States Medical Licensing Examination® (USMLE®), (Step 1) in relation to preadmission variables have been the subject of considerable study. Preadmissions variables such as the undergraduate grade point average (uGPA) and Medical College Admission Test® (MCAT®) scores, solely or in combination, have previously been found to be predictors of achievement in the basic science years and/or on the Step 1. The purposes of this retrospective study were to: (1) determine if our statistical analysis confirmed previously published relationships between preadmission variables (MCAT, uGPA, and applicant pool size), and (2) study correlates of the number of failures in five M1 courses with those preadmission variables and failures on Step 1. Statistical analysis confirmed previously published relationships between all preadmission variables. Only one course, Microscopic Anatomy, demonstrated significant correlations with all variables studied including the Step 1 failures. Physiology correlated with three of the four variables studied, but not with the Step 1 failures. Analyses such as these provide a tool by which administrators will be able to identify what courses are or are not responding in appropriate ways to changes in the preadmissions variables that signal student performance on the Step 1.

  2. Opening Address

    NASA Astrophysics Data System (ADS)

    Crovini, L.

    1994-01-01

    Ladies and Gentlemen To quote Mr Jean Terrien: "Physics must be one step ahead of metrology". A long-serving Director of the BIPM, he said these words when visiting the IMGC in 1970 as a member of the scientific board of our Institute. At that time it was still an open question whether the IMGC should start research work on the absolute measurement of silicon lattice spacing. Mr Terrien underlined the revolutionary character of x-ray interferometry and, eventually, he caused the balance needle to lean towards the ... right direction. Mr Terrien correctly foresaw that, like Michelson's interferometer of 1880, x-ray interferometry could have a prominent place in today's science and technology. And while, in the first case, after more than a century we can see instruments based on electromagnetic wave interaction within every one's reach in laboratories and, sometimes, in workshops, in the second case, twenty-five years since the first development of an x-ray interferometer we can witness its role in nanometrology. Today and tomorrow we meet to discuss how to go beyond the sixth decimal place in the value of the Avogadro constant. We are aware that the quest for this achievement requires the cooperation of scientists with complementary capabilities. I am sure that the present workshop is a very good opportunity to present and discuss results and to improve and extend existing cooperation. The new adjustment of fundamental constants envisaged by the CODATA Task Group is redoubling scientists' efforts to produce competitive values of NA. The results of the measurements of the silicon lattice spacing in terms of an optical wavelength, which were available for the 1986 adjustment, combined with the determination of silicon molar volume, demonstrate how such an NA determination produces a consistent set of other constants and opens the way to a possible redefinition of the kilogram. We shall see in these two days how far we have progressed along this road. For us at the

  3. Science, Religion, and Celebrations: A Paradigm for Teaching Holidays.

    ERIC Educational Resources Information Center

    Montgomery, Kathleen; Tansits-Wenze, Gloria

    2002-01-01

    With attention to basic legal issues, teachers can address holidays in meaningful ways. One approach is to organize the study of diverse religious holidays by equinoxes and solstices. This method highlights the connections between religion and science. (SK)

  4. Configuration of the hemoglobin oxygen dissociation curve demystified: a basic mathematical proof for medical and biological sciences undergraduates.

    PubMed

    Leow, Melvin Khee-Shing

    2007-06-01

    The oxygen dissociation curve (ODC) of hemoglobin (Hb) has been widely studied and mathematically described for nearly a century. Numerous mathematical models have been designed to predict with ever-increasing accuracy the behavior of oxygen transport by Hb in differing conditions of pH, carbon dioxide, temperature, Hb levels, and 2,3-diphosphoglycerate concentrations that enable their applications in various clinical situations. The modeling techniques employed in many existing models are notably borrowed from advanced and highly sophisticated mathematics that are likely to surpass the comprehensibility of many medical and bioscience students due to the high level of "mathematical maturity" required. It is, however, a worthy teaching point in physiology lectures to illustrate in simple mathematics the fundamental reason for the crucial sigmoidal configuration of the ODC such that the medical and bioscience undergraduates can readily appreciate it, which is the objective of this basic dissertation.

  5. Capturing and sequestering carbon by enhancing the natural carbon cycle: Prelimary identification of basic science needs and opportunities

    SciTech Connect

    Benson, S.M.

    1997-07-01

    This document summarizes proceedings and conclusions of a US DOE workshop. The purpose of the workshop was to identify the underlying research needed to answer the following questions: (1) Can the natural carbon cycle be used to aid in stabilizing or decreasing atmospheric CO{sub 2} and CH{sub 4} by: (a) Increasing carbon capture; (b) Preventing carbon from returning to the atmosphere through intermediate (<100 years) to long-term sequestration (> 100 years)?; and (2) What kind of ecosystem management practices could be used to achieve this? Three working groups were formed to discuss the terrestrial biosphere, oceans, and methane. Basic research needs identified included fundamental understanding of carbon cycling and storage in soils, influence of climate change and anthropogenic emissions on the carbon cycle, and carbon capture and sequestration in oceans. 2 figs., 4 tabs.

  6. NASA SMD E/PO Community Addresses the needs of the Higher Ed Community: Introducing Slide sets for the Introductory Earth and Space Science Instructor

    NASA Astrophysics Data System (ADS)

    Buxner, S.; Meinke, B. K.; Brain, D.; Schneider, N. M.; Schultz, G. R.; Smith, D. A.; Grier, J.; Shipp, S. S.

    2014-12-01

    The NASA Science Mission Directorate (SMD) Science Education and Public Outreach (E/PO) community and Forums work together to bring the cutting-edge discoveries of NASA Astrophysics and Planetary Science missions to the introductory astronomy college classroom. These mission- and grant-based E/PO programs are uniquely poised to foster collaboration between scientists with content expertise and educators with pedagogy expertise. We present two new opportunities for college instructors to bring the latest NASA discoveries in Space Science into their classrooms. The NASA Science Mission Directorate (SMD) Astrophysics Education and Public Outreach Forum is coordinating the development of a pilot series of slide sets to help Astronomy 101 instructors incorporate new discoveries in their classrooms. The "Astro 101 slide sets" are presentations 5-7 slides in length on a new development or discovery from a NASA Astrophysics mission relevant to topics in introductory astronomy courses. We intend for these slide sets to help Astronomy 101 instructors include new developments (discoveries not yet in their textbooks) into the broader context of the course. In a similar effort to keep the astronomy classroom apprised of the fast moving field of planetary science, the Division of Planetary Sciences (DPS) has developed the Discovery slide sets, which are 3-slide presentations that can be incorporated into college lectures. The slide sets are targeted at the Introductory Astronomy undergraduate level. Each slide set consists of three slides which cover a description of the discovery, a discussion of the underlying science, and a presentation of the big picture implications of the discovery, with a fourth slide includes links to associated press releases, images, and primary sources. Topics span all subdisciplines of planetary science, and sets are available in Farsi and Spanish. The NASA SMD Planetary Science Forum has recently partnered with the DPS to continue producing the

  7. Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches.

    PubMed

    Greten, Tim F; Wang, Xin W; Korangy, Firouzeh

    2015-05-01

    The recent approval of two immune checkpoint inhibitors for the treatment of malignant melanoma has sparked great interest by physicians and basic scientists searching for novel therapeutics for GI cancer. Chronic inflammation is recognised as a major risk factor for the development of hepatocellular carcinoma (HCC) and makes this type of cancer a potentially ideal target for an immune based treatment approach. Further evidence for a critical role of immune responses in patients with HCC is derived from the fact that immune signatures and profiles predict patients' outcome as well as the fact that tumour-induced spontaneous antitumour immunity can be detected. In addition ablative therapies can lead to changes in the number, phenotype and function of different immune cell subsets, which correlate with patients' survival. Various HCC-specific mouse models have been developed, which improve our understanding of hepatocarcinogenesis and tumour-immune cell interactions, and lead to the development of novel immune based treatment approaches, which are currently being evaluated in preclinical and in early clinical settings. Immune checkpoint blockade along with adoptive immune cell therapy and vaccine approaches are currently being evaluated either alone or in combination with other treatments. Here, we provide an overview for the rationale of immunotherapy in HCC, summarise ongoing studies and provide a perspective for immune based approaches in patients with HCC.

  8. Orthopaedic war injuries: from combat casualty care to definitive treatment: a current review of clinical advances, basic science, and research opportunities.

    PubMed

    Covey, Dana C; Aaron, Roy K; Born, Christopher T; Calhoun, Jason H; Einhorn, Thomas A; Hayda, Roman A; Levin, Lawrence Scott; Mazurek, Michael T; Murray, Clinton K; Powell, Elisha T; Schwarz, Edward M; Wenke, Joseph C

    2008-01-01

    Musculoskeletal war wounds often involve massive injury to bone and soft tissue that differ markedly in character and extent compared with most injuries seen in civilian practice. These complex injuries have challenged orthopaedic surgeons to the limits of their treatment abilities on the battlefield, during medical evacuation, and in subsequent definitive or reconstructive treatment. Newer methodologies are being used in the treatment of these wounds to prevent so-called second hit complications, decrease complications associated with prolonged medical evacuation, reduce the incidence of infection, and restore optimal function. Basic science advances hold the promise of providing foundations for future treatment options that may improve both bone and soft-tissue healing. Research on the treatment of these often devastating wounds also will have broad applicability to trauma resulting from acts of terrorism or from natural disasters.

  9. Autologous adipose-derived stem cells: Basic science, technique, and rationale for application in ulcer and wound healing.

    PubMed

    Zollino, Ilaria; Zuolo, Michele; Gianesini, Sergio; Pedriali, Massimo; Sibilla, Maria Grazia; Tessari, Mirko; Carinci, Francesco; Occhionorelli, Savino; Zamboni, Paolo

    2017-04-01

    Objectives The present review represents a translational boundary between basic research and surgery, particularly focusing on the promising application of adipose-derived stem cells harvested intra-operatively during debridement of venous leg ulcers. Methods We reviewed 830 out of 5578 articles on MEDLINE starting from 1997 and sorted by the relevance option. Results The technique currently used for adipose-derived stem cells intra-operative harvesting is presented, including a safety evaluation on a cohort of 5089 revised patients who underwent plastic surgery and maxillo-facial surgical procedures. Complications were reported in 169 cases (3.3%). One hundred and forty-one (2.77%) patients were classified as having minor complications, specifically: nodularity/induration 93 (1.83%), dysesthesia 14 (0.26%), hematoma 12 (0.23%), superficial infection 11 (0.21%), pain 7 (0.13%), poor cosmesis 3 (0.06%), and abnormal breast secretion 1 (0.02%), while 28 patients (0.55%) were classified as having major complications, specifically: deep infection 22 (0.43%), sepsis 3 (0.06%), abdominal hematoma 2 (0.04%), and pneumothorax 1 (0.02%). Application of cell therapy in venous leg ulcer is currently used only for patients not responding to the standard treatment. The review shows the lack of randomized clinical trials for application of adipose-derived stem cells among treatments for venous leg ulcer. Finally, adipose-derived stem cells implantation at the wound site promotes a new tissue formation rich in vascular structures and remodeling collagen. Conclusion Adipose-derived stem cells strategy represents a great opportunity for the treatment of chronic wounds, due to the simplicity of the technique and the application of cell treatment in the operating room immediately following debridement. However, clinical studies and data from randomized trials are currently lacking.

  10. Radiation Leukemogenesis: Applying Basic Science of Epidemiological Estimates of Low Dose Risks and Dose-Rate Effects

    SciTech Connect

    Hoel, D. G.

    1998-11-01

    The next stage of work has been to examine more closely the A-bomb leukemia data which provides the underpinnings of the risk estimation of CML in the above mentioned manuscript. The paper by Hoel and Li (Health Physics 75:241-50) shows how the linear-quadratic model has basic non-linearities at the low dose region for the leukemias including CML. Pierce et. al., (Radiation Research 123:275-84) have developed distributions for the uncertainty in the estimated exposures of the A-bomb cohort. Kellerer, et. al., (Radiation and Environmental Biophysics 36:73-83) has further considered possible errors in the estimated neutron values and with changing RBE values with dose and has hypothesized that the tumor response due to gamma may not be linear. We have incorporated his neutron model and have constricted new A-bomb doses based on his model adjustments. The Hoel and Li dose response analysis has also been applied using the Kellerer neutron dose adjustments for the leukemias. Finally, both Pierce's dose uncertainties and Kellerer neutron adjustments are combined as well as the varying RBE with dose as suggested by Rossi and Zaider and used for leukemia dose-response analysis. First the results of Hoel and Li showing a significantly improved fit of the linear-quadratic dose response by the inclusion of a threshold (i.e. low-dose nonlinearity) persisted. This work has been complete for both solid tumor as well as leukemia for both mortality as well as incidence data. The results are given in the manuscript described below which has been submitted to Health Physics.

  11. Human Health and the Biological Effects of Tritium in Drinking Water: Prudent Policy Through ScienceAddressing the ODWAC New Recommendation

    PubMed Central

    Dingwall, S.; Mills, C.E.; Phan, N.; Taylor, K.; Boreham, D.R.

    2011-01-01

    Tritium is a radioactive form of hydrogen and is a by-product of energy production in Canadian Deuterium Uranium (CANDU) reactors. The release of this radioisotope into the environment is carefully managed at CANDU facilities in order to minimize radiation exposure to the public. However, under some circumstances, small accidental releases to the environment can occur. The radiation doses to humans and non-human biota from these releases are low and orders of magnitude less than doses received from naturally occurring radioisotopes or from manmade activities, such as medical imaging and air travel. There is however a renewed interest in the biological consequences of low dose tritium exposures and a new limit for tritium levels in Ontario drinking water has been proposed. The Ontario Drinking Water Advisory Council (ODWAC) issued a formal report in May 2009 in response to a request by the Minister of the Environment, concluding that the Ontario Drinking Water Quality Standard for tritium should be revised from the current 7,000 Bq/L level to a new, lower 20 Bq/L level. In response to this recommendation, an international scientific symposium was held at McMaster University to address the issues surrounding this change in direction and the validity of a new policy. Scientists, regulators, government officials, and industrial stakeholders were present to discuss the potential health risks associated with low level radiation exposure from tritium. The regulatory, economic, and social implications of the new proposed limit were also considered. The new recommendation assumed a linear-no-threshold model to calculate carcinogenic risk associated with tritium exposure, and considered tritium as a non-threshold chemical carcinogen. Both of these assumptions are highly controversial given that recent research suggests that low dose exposures have thresholds below which there are no observable detrimental effects. Furthermore, mutagenic and carcinogenic risk calculated from

  12. Scientific Grand Challenges: Discovery In Basic Energy Sciences: The Role of Computing at the Extreme Scale - August 13-15, 2009, Washington, D.C.

    SciTech Connect

    Galli, Giulia; Dunning, Thom

    2009-08-13

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) and Office of Advanced Scientific Computing Research (ASCR) workshop in August 2009 on extreme-scale computing provided a forum for more than 130 researchers to explore the needs and opportunities that will arise due to expected dramatic advances in computing power over the next decade. This scientific community firmly believes that the development of advanced theoretical tools within chemistry, physics, and materials science—combined with the development of efficient computational techniques and algorithms—has the potential to revolutionize the discovery process for materials and molecules with desirable properties. Doing so is necessary to meet the energy and environmental challenges of the 21st century as described in various DOE BES Basic Research Needs reports. Furthermore, computational modeling and simulation are a crucial complement to experimental studies, particularly when quantum mechanical processes controlling energy production, transformations, and storage are not directly observable and/or controllable. Many processes related to the Earth’s climate and subsurface need better modeling capabilities at the molecular level, which will be enabled by extreme-scale computing.

  13. A qualitative study on personal information management (PIM) in clinical and basic sciences faculty members of a medical university in Iran

    PubMed Central

    Sedghi, Shahram; Abdolahi, Nida; Azimi, Ali; Tahamtan, Iman; Abdollahi, Leila

    2015-01-01

    Background: Personal Information Management (PIM) refers to the tools and activities to save and retrieve personal information for future uses. This study examined the PIM activities of faculty members of Iran University of Medical Sciences (IUMS) regarding their preferred PIM tools and four aspects of acquiring, organizing, storing and retrieving personal information. Methods: The qualitative design was based on phenomenology approach and we carried out 37 interviews with clinical and basic sciences faculty members of IUMS in 2014. The participants were selected using a random sampling method. All interviews were recorded by a digital voice recorder, and then transcribed, codified and finally analyzed using NVivo 8 software. Results: The use of PIM electronic tools (e-tools) was below expectation among the studied sample and just 37% had reasonable knowledge of PIM e-tools such as, external hard drivers, flash memories etc. However, all participants used both paper and electronic devices to store and access information. Internal mass memories (in Laptops) and flash memories were the most used e-tools to save information. Most participants used "subject" (41.00%) and "file name" (33.7 %) to save, organize and retrieve their stored information. Most users preferred paper-based rather than electronic tools to keep their personal information. Conclusion: Faculty members had little knowledge about PIM techniques and tools. Those who organized personal information could easier retrieve the stored information for future uses. Enhancing familiarity with PIM tools and training courses of PIM tools and techniques are suggested. PMID:26793648

  14. Encouraging upward thinking with planetary imagery: science as motivator and enrichment for the adult basic skills learner

    NASA Astrophysics Data System (ADS)

    Fisher, C. G.; Fisher, K. E.

    2004-12-01

    Engaging students in the process of understanding the world around them in a college level remedial reading program presents an unmitigated challenge. Students previously unimpressed with the educational system become more active participants in their classrooms when high resolution prints from Landsat obtained from the NASA-GSFC education outreach center are used to initially motivate them to perceive the context of their surroundings. In the course, imagery from Landsat that clearly show the Compton Community College track is introduced, moving on to show students similar perspectives on Egyptian pyramids and other remote regions. The satellite imagery makes understanding maps intuitive. After linking these observations from space to both the student's own experience and far away places on earth, students are introduced to the Star-date publication [http://Stardate.org]. Students are encouraged to individually follow the phases of the moon, find constellations, visit the College's telescope on nights when the astronomy class makes observations, and look for meteor showers. NASA and JPL sites are then used to teach students to access the web. Students receive instruction in using computers to navigate the web, where they then follow missions in real time, and access archived imagery and written materials. These sources of reading material are particularly valuable because they are written simply, but follow the scientific convention of addressing readers as colleagues. Notably, students have returned after completing the three-course sequence to literacy and commented on the importance to them of having learned about space in the initial course. They have reported on the excitement of teaching their children and others in the community about what they can see by looking up, and indicated their appreciation of receiving posters and handouts obtained at this meeting by displaying them prominently in their homes. Although not a traditional venue for scientific

  15. Experience of the creative Space-Astrophysics Education in Israeli Science-Educational Center "Blossoms of Science" - creative activity from mini-projects in basic school to ASTROTOP-projects for graduates

    NASA Astrophysics Data System (ADS)

    Pustil'Nik, L.; Pundak, D.

    We present 12 year experience of educational project in Space Astrophysics Environment field realized on the base of National Science-Educational Center Blossoms of Science of the Jordan Valley College Our approach is based on the natural curiosity of children as driver of their self-development from the first minutes of their life and even in adult state This approach shift center of the weight in educational process from direct lectures sermons explanation from teacher to children on own attempts of children to investigate problem what is interesting for them by themselves individually or in group Our approach includes four levels of the projects nano-projects for children garden and basic school up to 10-12 years micro-projects for intermediate school 12-16 years mini-projects for high school 16-18 years and macro-projects for the best graduates high schools and students of colleges 17-22 years These levels and projects are interconnected one with another and sometimes participants started on the micro-projects level in intermediate school continue their activity up to macro-projects of the graduate s diploma level For each level we organize courses for preparation of the teachers and instructors interested in the using of our receipts and published books and brochures for them The content of our activity for different levels a Level of kinder gardens-basic schools -- special software with interactive movie - - nano-projects b Level of intermediate school Days of Science in tens schools of Israel--

  16. The impact of the Alzheimer's Disease Neuroimaging Initiative 2: What role do public-private partnerships have in pushing the boundaries of clinical and basic science research on Alzheimer's disease?

    PubMed

    Jones-Davis, Dorothy M; Buckholtz, Neil

    2015-07-01

    In the growing landscape of biomedical public-private-partnerships, particularly for Alzheimer's disease, the question is posed as to their value. What impacts do public-private-partnerships have on clinical and basic science research in Alzheimer's disease? The authors answer the question using the Alzheimer's Disease Neuroimaging Initiative (ADNI) as a test case and example. ADNI is an exemplar of how public-private-partnerships can make an impact not only on clinical and basic science research and practice (including clinical trials), but also of how similar partnerships using ADNI as an example, can be designed to create a maximal impact within their fields.

  17. Establishing a culture of care, conscience, and responsibility: addressing the improvement of scientific discovery and animal welfare through science-based performance standards.

    PubMed

    Klein, H J; Bayne, K A

    2007-01-01

    Science-based performance standards offer a viable means of reducing regulatory burden while ensuring that research animal welfare and high-quality research data are realized. Unlike rigid regulations, science-based performance standards evolve as new information becomes available, thereby allowing new discoveries to be implemented in a timely manner and in a way that more effectively benefits the animals and the science. The implementation of performance standards requires a well-coordinated institutional team composed of the administration, research staff, the institutional animal care and use committee, professional and technical animal care personnel, occupational health and safety staff, and physical plant staff. This animal program team is best supported in an institutional environment that reflects a culture of care, compliance, and responsibility. In such a culture, the professional judgment exercised by the team is well grounded in meeting the diverse needs of the program's customers, who include the animals, the researchers, and research stakeholders such as the public. The institutional culture of care, compliance, and responsibility fosters workplace integrity, an ethics-based decision-making paradigm, sound understanding of institutional expectations through good communication and clear lines of authority, the hiring and retention of trained and well-qualified individuals, and a system for continuous development and improvement of the program.

  18. "New Voices": Enduring Basic Writing

    ERIC Educational Resources Information Center

    Bourgeois, Pamela

    2008-01-01

    This article addresses the issue of basic writing, demonstrating how one university's basic writing program acts as a steward of writing. The assumption that basic writers only consume resources rather than contribute to academic excellence is rejected. What links the author responses to this issue is a publication of student writing entitled…

  19. Content addressable memory project

    NASA Technical Reports Server (NTRS)

    Hall, Josh; Levy, Saul; Smith, D.; Wei, S.; Miyake, K.; Murdocca, M.

    1991-01-01

    The progress on the Rutgers CAM (Content Addressable Memory) Project is described. The overall design of the system is completed at the architectural level and described. The machine is composed of two kinds of cells: (1) the CAM cells which include both memory and processor, and support local processing within each cell; and (2) the tree cells, which have smaller instruction set, and provide global processing over the CAM cells. A parameterized design of the basic CAM cell is completed. Progress was made on the final specification of the CPS. The machine architecture was driven by the design of algorithms whose requirements are reflected in the resulted instruction set(s). A few of these algorithms are described.

  20. Symmetry in the Basic Sciences

    DTIC Science & Technology

    1989-04-01

    close together and the water-jet propulsion exhibited by ammonoids and nautiloids in this situation would result in spinning rather than efficient...negative energy states predicted by the Klein-,ordon equation represent antimatter , a prediction that is justified by the increased symmnetry of this

  1. Basic science of climate change

    SciTech Connect

    Maskell, K.; Callander, B.A. ); Mintzer, I.M. )

    1993-10-23

    Anthropogenic emissions of greenhouse gases are enhancing the natural greenhouse effect. There is almost universal agreement in the scientific community that this will lead to a warming of the lower atmosphere and of the earth's surface. However, the exact timing, magnitude, and regional distribution of this future warming are very uncertain. Merely taking account of changes in the global mean climate is not enough, especially when considering the impacts of climate change. Man also have to consider the rate and regional distribution of climate change and changes in the frequency of events. An increase in the frequency of extremes, such as droughts and storms, and rapid climate change are two factors which could have dramatic effects on human society and natural ecosystems. However, systems already under stress or close to their climate limits are likely to experience the greatest difficulty in adapting to change. Although human activity has been increasing greenhouse gas concentrations for a hundred years, man cannot yet detect unequivocally a greenhouse gas induced signal in climate records. However, increases in greenhouse gas concentrations are almost bound to continue and are likely to emerge as the dominant perturbation of the earth's climate in the coming decades.

  2. Health Instruction Packages: Basic Sciences.

    ERIC Educational Resources Information Center

    Cathey, Barbara; And Others

    Text, illustrations, and exercises are utilized in a set of nine learning modules designed to instruct nursing and allied health students in a variety of biological topics. The first module, by Barbara Cathey, discusses cell growth and the proliferation of cells in benign and malignant tumors. The second module, by Eugene Volz, describes the…

  3. Basic Studies in Microwave Sciences

    DTIC Science & Technology

    2010-03-22

    nanofluidic channel fabrication. For the second task, a CMOS transmission line based pulse capture and analysis circuit is proposed and analyzed...Additionally, two provisional patent applications have been filed. Due to the results from the planar nanofluidic channel work in this project, NSF is...MV/cm.   A new  technique  is proposed and demonstrated  for sub‐10 nm planar  nanofluidic  channel fabrication.   For the second task, a CMOS

  4. Basic Research in Computer Science

    DTIC Science & Technology

    1993-10-01

    report has been reviewed and is approved for publication. 72 , +_ CHAHIRA M. HOPPER, Project Engineer ’JERRY L. COVERT, Chief Advanced Systems Research...relationships. Finally, operators are defined graphically by pre- state and post -state specifications. From these graphical images the corresponding...cities. Packages are carried within the same city in trucks and between cities in airplanes. At each city there are several locations, e.g., post

  5. Basic Research in Computer Science

    DTIC Science & Technology

    1993-12-22

    from Observation. Annual Research Review 1990{):37-53, 1991. [Ikeuchi et al. 93a] Ikeuchi, K., Kawade, M., and Suehiro, T. Assembly Task Recognition...proposal. In [Tygar 92] we review new developments in computer security architectures, including zero-knowledge proofs, secure coprocessors, and high...States are represented graphically by building multiple objects and relationships. Finally, operators are defined graphically by pre- state and post

  6. Formative research on the primo vascular system and acceptance by the korean scientific community: the gap between creative basic science and practical convergence technology.

    PubMed

    Kim, Hoon Gi

    2013-12-01

    The purpose of this study was to trace the formative process of primo vascular system (PVS) research over the past decade and to describe the characteristics of the Korean scientific community. By publishing approximately 30 papers in journals ranking in the Science Citation Index (Expanded), the PVS research team actively convinced domestic and international scientists of the anatomical existence of the PVS and its possible application to Korean and Western medicine. In addition, by sharing the PVS observation technique, the team promoted the dissemination and further pursuit of the research. In 2012, however, PVS researchers performed smaller scale research without advancing to a higher level as compared to the early days. The main reasons were found to be the Korean Research and Development policy of supporting creative, small-scale basic research and applied research of Western scientific fields that promised potentially greater success on an extensive scale; the indifference concerning, and the disbelief in, the existence of a new circulatory system were shown by the Western medical community. In addition, the Oriental medical community was apathetic about working with the PVS team. Professors Kwang-Sup Soh and Byung-Cheon Lee were the prime movers of PVS research under difficult conditions. Spurred by their belief in the existence and significance of the PVS, they continued with their research despite insufficient experimental data. The Korean scientific community is not ready to promote the Korea-oriented creative field of the PVS team.

  7. Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US.

    PubMed

    Gibbs, Kenneth D; Basson, Jacob; Xierali, Imam M; Broniatowski, David A

    2016-11-17

    Faculty diversity is a longstanding challenge in the US. However, we lack a quantitative and systemic understanding of how the career transitions into assistant professor positions of PhD scientists from underrepresented minority (URM) and well-represented (WR) racial/ethnic backgrounds compare. Between 1980 and 2013, the number of PhD graduates from URM backgrounds increased by a factor of 9.3, compared with a 2.6-fold increase in the number of PhD graduates from WR groups. However, the number of scientists from URM backgrounds hired as assistant professors in medical school basic science departments was not related to the number of potential candidates (R(2)=0.12, p>0.07), whereas there was a strong correlation between these two numbers for scientists from WR backgrounds (R(2)=0.48, p<0.0001). We built and validated a conceptual system dynamics model based on these data that explained 79% of the variance in the hiring of assistant professors and posited no hiring discrimination. Simulations show that, given current transition rates of scientists from URM backgrounds to faculty positions, faculty diversity would not increase significantly through the year 2080 even in the context of an exponential growth in the population of PhD graduates from URM backgrounds, or significant increases in the number of faculty positions. Instead, the simulations showed that diversity increased as more postdoctoral candidates from URM backgrounds transitioned onto the market and were hired.

  8. Improved wound management by regulated negative pressure-assisted wound therapy and regulated, oxygen- enriched negative pressure-assisted wound therapy through basic science research and clinical assessment.

    PubMed

    Topaz, Moris

    2012-05-01

    Regulated negative pressure-assisted wound therapy (RNPT) should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last two decades. RNPT systems maintain the treated wound's environment as a semi-closed, semi-isolated system applying external physical stimulations to the wound, leading to biological and biochemical effects, with the potential to substantially influence wound-host interactions, and when properly applied may enhance wound healing. RNPT is a simple, safe, and affordable tool that can be utilized in a wide range of acute and chronic conditions, with reduced need for complicated surgical procedures, and antibiotic treatment. This technology has been shown to be effective and safe, saving limbs and lives on a global scale. Regulated, oxygen-enriched negative pressure-assisted wound therapy (RO-NPT) is an innovative technology, whereby supplemental oxygen is concurrently administered with RNPT for their synergistic effect on treatment and prophylaxis of anaerobic wound infection and promotion of wound healing. Understanding the basic science, modes of operation and the associated risks of these technologies through their fundamental clinical mechanisms is the main objective of this review.

  9. A model for considering different discourse communities within the toxicological and environmental sciences: an approach for addressing jargon and personally subjective vocabulary.

    PubMed

    Broyles, Cristopher D

    2011-07-15

    Discourse speak is a powerful communication shorthand between individuals in the same discourse group. Discourse speak consists of both jargon, the unique--but understood--terminology used in the discourse group, and a member's own personally subjective vocabulary, wording that is commonly used in the discourse group but has no true consensus-based meaning. It is my observation that sometimes when scientists write, they generally focus solely on content (the pedant's stance), and, consequently, can fail to consciously consider audience, and, by extension, they fail to anticipate that their publication may reach beyond their own discourse group. If scientists do not consciously consider their intended audience and do not adapt their language for "outsiders" who might be part of the audience, the usefulness of the publication becomes limited because the intended meaning can be lost. Thus, as explained in the subsequent commentary, effective communication in the sciences not only involves defendable science but, also, a conscious perception of audience through a deliberate recognition of one's own discourse speak.

  10. [Keynote address: Climate change

    SciTech Connect

    Forrister, D.

    1994-12-31

    Broadly speaking, the climate issue is moving from talk to action both in the United States and internationally. While few nations have adopted strict controls or stiff new taxes, a number of them are developing action plans that are making clear their intention to ramp up activity between now and the year 2000... and beyond. There are sensible, economically efficient strategies to be undertaken in the near term that offer the possibility, in many countries, to avoid more draconian measures. These strategies are by-and-large the same measures that the National Academy of Sciences recommended in a 1991 report called, Policy Implications of Greenhouse Warming. The author thinks the Academy`s most important policy contribution was how it recommended the nations act in the face of uncertain science and high risks--that cost effective measures are adopted as cheap insurance... just as nations insure against other high risk, low certainty possibilities, like catastrophic health insurance, auto insurance, and fire insurance. This insurance theme is still right. First, the author addresses how the international climate change negotiations are beginning to produce insurance measures. Next, the author will discuss some of the key issues to watch in those negotiations that relate to longer-term insurance. And finally, the author will report on progress in the United States on the climate insurance plan--The President`s Climate Action Plan.

  11. Addressing Environmental Health Inequalities

    PubMed Central

    Gouveia, Nelson

    2016-01-01

    Environmental health inequalities refer to health hazards disproportionately or unfairly distributed among the most vulnerable social groups, which are generally the most discriminated, poor populations and minorities affected by environmental risks. Although it has been known for a long time that health and disease are socially determined, only recently has this idea been incorporated into the conceptual and practical framework for the formulation of policies and strategies regarding health. In this Special Issue of the International Journal of Environmental Research and Public Health (IJERPH), “Addressing Environmental Health Inequalities—Proceedings from the ISEE Conference 2015”, we incorporate nine papers that were presented at the 27th Conference of the International Society for Environmental Epidemiology (ISEE), held in Sao Paulo, Brazil, in 2015. This small collection of articles provides a brief overview of the different aspects of this topic. Addressing environmental health inequalities is important for the transformation of our reality and for changing the actual development model towards more just, democratic, and sustainable societies driven by another form of relationship between nature, economy, science, and politics. PMID:27618906

  12. Basic Experiments in Telecommunications.

    ERIC Educational Resources Information Center

    Andresen, S. G.

    Presented is a set of laboratory experiments developed to provide students with demonstrations and hands-on experiences with a variety of basic communications methods. These experiments may be used with students who have training in engineering, as well as those with social sciences who have no engineering background. Detailed exercises dealing…

  13. Anesthesia Basics

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Anesthesia Basics KidsHealth > For Teens > Anesthesia Basics Print A ... español Conceptos básicos sobre la anestesia What Is Anesthesia? No doubt about it, getting an operation can ...

  14. Basic Soils. Revision.

    ERIC Educational Resources Information Center

    Montana State Univ., Bozeman. Dept. of Agricultural and Industrial Education.

    This curriculum guide is designed for use in teaching a course in basic soils that is intended for college freshmen. Addressed in the individual lessons of the unit are the following topics: the way in which soil is formed, the physical properties of soil, the chemical properties of soil, the biotic properties of soil, plant-soil-water…

  15. Basic Engineer Equipment Mechanic.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by basic engineer equipment mechanics. Addressed in the four individual units of the course are the following topics: mechanics and their tools (mechanics, hand tools, and power…

  16. Basics of Online Searching.

    ERIC Educational Resources Information Center

    Meadow, Charles T.; Cochrane, Pauline (Atherton)

    Intended to teach the principles of interactive bibliographic searching to those with little or no prior experience, this textbook explains the basic elements of online information retrieval and compares the major database search systems. Its chapters address (1) relevant definitions and vocabulary; (2) the conceptual facets of database searching,…

  17. Thinking about Thinking and Emotion: The Metacognitive Approach to the Medical Humanities that Integrates the Humanities with the Basic and Clinical Sciences

    PubMed Central

    Eichbaum, Quentin G

    2014-01-01

    Medical knowledge in recent decades has grown prodigiously and has outstripped the capacity of the human brain to absorb and understand it all. This burgeoning of knowledge has created a dilemma for medical educators. We can no longer expect students to continue memorizing this large body of increasingly complex knowledge. Instead, our efforts should be redirected at developing in students a competency as flexible thinkers and agile learners so they can adeptly deal with new knowledge, complexity, and uncertainty in a rapidly changing world. Such a competency would entail not only cognitive but also emotional skills essential for the holistic development of their professional identity. This article will argue that metacognition—“thinking about thinking (and emotion)”—offers the most viable path toward developing this competency. The overwhelming volume of medical knowledge has driven some medical schools to reduce the time allocated in their curricula to the “soft-option” humanities as they tend to consider them an expendable “luxury.” Vanderbilt University School of Medicine, Nashville, TN, has moved away from the traditional conception of the medical humanities as “the arts,” composed of art, music, and literature, toward an approach that integrates the humanities with the basic and clinical sciences, based on metacognition. This metacognitive approach to the humanities, described in this article, has three goals: 1) to develop students as flexible thinkers and agile learners and to provide them with essential cognitive and emotional skills for navigating medical complexity and uncertainty; 2) to elicit in students empathy and tolerance by making them aware of the immense diversity in human cognition (and emotion); and 3) to integrate the humanities with the basic and clinical sciences. Through this metacognitive approach, students come to understand their patterns of cognition and emotions, and in the group setting, they learn to mindfully

  18. Thinking about thinking and emotion: the metacognitive approach to the medical humanities that integrates the humanities with the basic and clinical sciences.

    PubMed

    Eichbaum, Quentin G

    2014-01-01

    Medical knowledge in recent decades has grown prodigiously and has outstripped the capacity of the human brain to absorb and understand it all. This burgeoning of knowledge has created a dilemma for medical educators. We can no longer expect students to continue memorizing this large body of increasingly complex knowledge. Instead, our efforts should be redirected at developing in students a competency as flexible thinkers and agile learners so they can adeptly deal with new knowledge, complexity, and uncertainty in a rapidly changing world. Such a competency would entail not only cognitive but also emotional skills essential for the holistic development of their professional identity. This article will argue that metacognition--“thinking about thinking (and emotion)”--offers the most viable path toward developing this competency. The overwhelming volume of medical knowledge has driven some medical schools to reduce the time allocated in their curricula to the “soft-option” humanities as they tend to consider them an expendable “luxury.” Vanderbilt University School of Medicine, Nashville, TN, has moved away from the traditional conception of the medical humanities as “the arts,” composed of art, music, and literature, toward an approach that integrates the humanities with the basic and clinical sciences, based on metacognition. This metacognitive approach to the humanities, described in this article, has three goals: 1) to develop students as flexible thinkers and agile learners and to provide them with essential cognitive and emotional skills for navigating medical complexity and uncertainty; 2) to elicit in students empathy and tolerance by making them aware of the immense diversity in human cognition (and emotion); and 3) to integrate the humanities with the basic and clinical sciences. Through this metacognitive approach, students come to understand their patterns of cognition and emotions, and in the group setting, they learn to mindfully

  19. Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome.

    PubMed

    Gross, Oliver; Kashtan, Clifford E; Rheault, Michelle N; Flinter, Frances; Savige, Judith; Miner, Jeffrey H; Torra, Roser; Ars, Elisabet; Deltas, Constantinos; Savva, Isavella; Perin, Laura; Renieri, Alessandra; Ariani, Francesca; Mari, Francesca; Baigent, Colin; Judge, Parminder; Knebelman, Bertrand; Heidet, Laurence; Lagas, Sharon; Blatt, Dave; Ding, Jie; Zhang, Yanqin; Gale, Daniel P; Prunotto, Marco; Xue, Yong; Schachter, Asher D; Morton, Lori C G; Blem, Jacqui; Huang, Michael; Liu, Shiguang; Vallee, Sebastien; Renault, Daniel; Schifter, Julia; Skelding, Jules; Gear, Susie; Friede, Tim; Turner, A Neil; Lennon, Rachel

    2016-05-10

    Alport syndrome (AS) is a genetic disease characterized by haematuric glomerulopathy variably associated with hearing loss and anterior lenticonus. It is caused by mutations in the COL4A3, COL4A4 or COL4A5 genes encoding the α3α4α5(IV) collagen heterotrimer. AS is rare, but it accounts for >1% of patients receiving renal replacement therapy. Angiotensin-converting enzyme inhibition slows, but does not stop, the progression to renal failure; therefore, there is an urgent requirement to expand and intensify research towards discovering new therapeutic targets and new therapies. The 2015 International Workshop on Alport Syndrome targeted unmet needs in basic science, genetics and diagnosis, clinical research and current clinical care. In three intensive days, more than 100 international experts including physicians, geneticists, researchers from academia and industry, and patient representatives from all over the world participated in panel discussions and breakout groups. This report summarizes the most important priority areas including (i) understanding the crucial role of podocyte protection and regeneration, (ii) targeting mutations by new molecular techniques for new animal models and potential gene therapy, (iii) creating optimal interaction between nephrologists and geneticists for early diagnosis, (iv) establishing standards for mutation screening and databases, (v) improving widespread accessibility to current standards of clinical care, (vi) improving collaboration with the pharmaceutical/biotech industry to investigate new therapies, (vii) research in hearing loss as a huge unmet need in Alport patients and (viii) the need to evaluate the risk and benefit of novel (including 'repurposing') therapies on an international basis.

  20. Use of the NBME Comprehensive Basic Science Examination as a progress test in the preclerkship curriculum of a new medical school.

    PubMed

    Johnson, Teresa R; Khalil, Mohammed K; Peppler, Richard D; Davey, Diane D; Kibble, Jonathan D

    2014-12-01

    In the present study, we describe the innovative use of the National Board of Medical Examiners (NBME) Comprehensive Basic Science Examination (CBSE) as a progress test during the preclerkship medical curriculum. The main aim of this study was to provide external validation of internally developed multiple-choice assessments in a new medical school. The CBSE is a practice exam for the United States Medical Licensing Examination (USMLE) Step 1 and is purchased directly from the NBME. We administered the CBSE five times during the first 2 yr of medical school. Student scores were compared with scores on newly created internal summative exams and to the USMLE Step 1. Significant correlations were observed between almost all our internal exams and CBSE scores over time as well as with USMLE Step 1 scores. The strength of correlations of internal exams to the CBSE and USMLE Step 1 broadly increased over time during the curriculum. Student scores on courses that have strong emphasis on physiology and pathophysiology correlated particularly well with USMLE Step 1 scores. Student progress, as measured by the CBSE, was found to be linear across time, and test performance fell behind the anticipated level by the end of the formal curriculum. These findings are discussed with respect to student learning behaviors. In conclusion, the CBSE was found to have good utility as a progress test and provided external validation of our new internally developed multiple-choice assessments. The data also provide performance benchmarks both for our future students to formatively assess their own progress and for other medical schools to compare learning progression patterns in different curricular models.