Science.gov

Sample records for address long-standing questions

  1. DOD Inventory of Contracted Services: Timely Decisions and Further Actions Needed to Address Long Standing Issues

    DTIC Science & Technology

    2016-10-01

    other category of service. Most of these functions were identified by the Army using its long-standing review process. The military departments...in deciding on the path forward for its underlying inventory data collection system, staffing its inventory management support office, and formalizing...required DOD to compile and review an annual inventory of its contracted services to identify the number of contractors performing services and the

  2. Looking at Photoinduced Charge Transfer Processes in the IR: Answers to Several Long-Standing Questions.

    PubMed

    Dereka, Bogdan; Koch, Marius; Vauthey, Eric

    2017-02-21

    Because of its crucial role in many areas of science and technology, photoinduced electron transfer is the most investigated photochemical reaction. Despite this, several important questions remain open. We present recent efforts to answer some of them, which concern both inter- and intramolecular processes. The decisive factor that allowed these issues to be successfully addressed was the use of time-resolved infrared (TRIR) spectroscopy. Many different transient species, such as tight and loose ion pairs (TIPs and LIPs) and exciplexes, have been invoked to explain the dynamics of intermolecular photoinduced charge separation reactions (i.e., electron transfer between two neutral species) and the production of free ions. However, their structures are essentially unknown, and their exact roles in the reaction mechanism are unclear. Indeed, the commonly used transient electronic absorption spectroscopy does not give much structural insight and cannot clearly distinguish ion pairs from free ions, at least in the visible region. Unambiguous spectral signatures of TIPs, LIPs, and exciplexes could be observed in the IR using electron donor/acceptor (D/A) pairs with adequate vibrational marker modes. The ability to spectrally distinguish these intermediates allowed their dynamics to be disentangled and their roles to be determined. Structural information could be obtained using polarization-resolved TRIR spectroscopy. Our investigations reveal that moderately to highly exergonic reactions result in the formation of both TIPs and LIPs. TIPs are not only generated upon direct charge-transfer excitation of DA complexes, as usually assumed, but are also formed upon static quenching with reactant pairs at distances and orientations enabling charge separation without diffusion. On the other hand, dynamic quenching produces primarily LIPs. In the case of highly exergonic reactions, strong indirect evidence for the generation of ion pairs in an electronic excited state was found

  3. Addressing Phonological Questions with Ultrasound

    ERIC Educational Resources Information Center

    Davidson, Lisa

    2005-01-01

    Ultrasound can be used to address unresolved questions in phonological theory. To date, some studies have shown that results from ultrasound imaging can shed light on how differences in phonological elements are implemented. Phenomena that have been investigated include transitional schwa, vowel coalescence, and transparent vowels. A study of…

  4. DOD Financial Management: Actions Under Way Need to Be Successfully Completed to Address Long-standing Funds Control Weaknesses

    DTIC Science & Technology

    2014-04-01

    general ledger, funds control, receipts and acceptance, accounts payable and disbursement, billing, and financial reporting for the general fund...Control Weaknesses Report to Congressional Requesters April 2014 GAO-14-94 United States Government Accountability Office Report Documentation...5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Government Accountability Office,441 G Street NW

  5. Business Education: Addressing the "What" Question

    ERIC Educational Resources Information Center

    Almoharby, Darwish

    2008-01-01

    In an attempt to diversify the economy and stimulate private enterprise development, government agencies and private institutions in many countries have emphasized the importance of setting up and developing small and medium-size enterprises and promoting entrepreneurship. An important question confronting policy makers, however, is how they can…

  6. Basic Physics Questions Addressed by Astrophysics

    NASA Technical Reports Server (NTRS)

    Mather, John C.

    2009-01-01

    Dark matter, dark energy, the Big Bang, testing relativity -- all are physics questions accessible to astrophysicists -- but all require new equipment. As Harwit's "Cosmic Discovery" pointed out, almost all great surprises in astronomy came from new equipment or new uses of equipment designed for other purposes, and many of those had military applications. I will outline prospects for new equipment and discuss how that equipment can be developed and built. Bigger and lighter mirrors, wavefront sensing and control, new detector technology, cryogenics -- each has its own social network, its own special possibilities, and its own funding sources outside science. I will discuss some examples drawn from real-life experience with the James Webb Space Telescope, a telescope that was said to have a "giggle factor" when it was proposed in 1995. Now each of the 10 major technologies has been brought to maturity, flight hardware is being built, and launch is planned for 2014. As an instrument builder all my life, I will speculate a little on what may be within our reach over the next few decades.

  7. Addressing Parental Vaccination Questions in the School Setting

    ERIC Educational Resources Information Center

    Luthy, Karlen E.; Burningham, Jana; Eden, Lacey M.; Macintosh, Janelle L. B.; Beckstrand, Renea L.

    2016-01-01

    School nurses work in a unique environment with key opportunities to address parental concerns and questions regarding their child's health. A common concern for parents during school enrollment is childhood vaccination safety and efficacy. As public health leaders, school nurses are well respected among parents, therefore school nurses are in a…

  8. Secondary Data Analysis: An Important Tool for Addressing Developmental Questions

    ERIC Educational Resources Information Center

    Greenhoot, Andrea Follmer; Dowsett, Chantelle J.

    2012-01-01

    Existing data sets can be an efficient, powerful, and readily available resource for addressing questions about developmental science. Many of the available databases contain hundreds of variables of interest to developmental psychologists, track participants longitudinally, and have representative samples. In this article, the authors discuss the…

  9. Addressing Questions on Life in Terrestrial Geothermal Systems

    NASA Astrophysics Data System (ADS)

    Hedlund, Brian P.; Li, Wen-Jun; Zhang, Chuanlun

    2013-09-01

    A binational research team met on the campus of Yunnan University in Kunming, China, to discuss recent progress and future plans to leverage binational support to address major questions on life in terrestrial geothermal systems. The symposium included about 90 faculty, postdocs, and students from China and about 30 faculty, postdocs, students, and high school teachers from the United States. The introductory session reviewed the progress of the Tengchong PIRE project funded by the U.S. National Science Foundation (NSF) Partnerships for International Research and Education (PIRE) program (OISE-0836450). It also introduced a new collaborative project funded as a Key Project of International Cooperation by the Chinese Ministry of Science and Technology (MOST, 2013DFA31980), which is the first project funded through a memorandum of understanding between NSF and MOST to promote China-U.S. collaboration.

  10. Preventing and Addressing Challenging Behavior: Common Questions and Practical Strategies

    ERIC Educational Resources Information Center

    Hemmeter, Mary Louise; Ostrosky, Michaelene M.; Corso, Robert M.

    2012-01-01

    The purpose of this article is to offer preschool teachers strategies for preventing challenging behavior and supporting the development of social skills and emotional competencies. This article is framed in a question and answer format using questions from teachers who the authors have worked with in the past. These questions and strategies are…

  11. Three Naive Questions: Addressed to the Modern Educational Optimism

    ERIC Educational Resources Information Center

    Krstic, Predrag

    2016-01-01

    This paper aims to question anew the popular and supposedly self-evident affirmation of education, in its modern incarnation as in its historical notion. The "naive" questions suggest that we have recently taken for granted that education ought to be for the masses, that it ought to be upbringing, and that it is better than ignorance.…

  12. Optimizing available network resources to address questions in environmental biogeochemistry

    USGS Publications Warehouse

    Hinckley, Eve-Lyn; Suzanne Andersen,; Baron, Jill S.; Peter Blanken,; Gordon Bonan,; William Bowman,; Sarah Elmendorf,; Fierer, Noah; Andrew Fox,; Keli Goodman,; Katherine Jones,; Danica Lombardozzi,; Claire Lunch,; Jason Neff,; Michael SanClements,; Katherine Suding,; Will Wieder,

    2016-01-01

    An increasing number of network observatories have been established globally to collect long-term biogeochemical data at multiple spatial and temporal scales. Although many outstanding questions in biogeochemistry would benefit from network science, the ability of the earth- and environmental-sciences community to conduct synthesis studies within and across networks is limited and seldom done satisfactorily. We identify the ideal characteristics of networks, common problems with using data, and key improvements to strengthen intra- and internetwork compatibility. We suggest that targeted improvements to existing networks should include promoting standardization in data collection, developing incentives to promote rapid data release to the public, and increasing the ability of investigators to conduct their own studies across sites. Internetwork efforts should include identifying a standard measurement suite—we propose profiles of plant canopy and soil properties—and an online, searchable data portal that connects network, investigator-led, and citizen-science projects.

  13. Questions Addressed to V.V. Putin during an Internet Conference on Careers

    ERIC Educational Resources Information Center

    Agranovich, M.; Zair-Bek, S.; Seliverstova, I.; Shishmakova, E.

    2007-01-01

    On instructions from the Ministry of Education of the Russian Federation, the Federal Institute for the Development of Education prepared an analytical report on the topic "Questions Addressed to Russian President V.V. Putin During an Internet Conference on 6 July 2006 on the Problems of "Career"." That document presents an…

  14. A Nominal Balloon Instrument Payload to Address Questions from the Planetary Decadal Survey

    NASA Astrophysics Data System (ADS)

    Young, Eliot; Kremic, Tibor; Dankanich, John

    The Planetary Science Decadal Survey (entitled "Visions and Voyages for Planetary Science in the Decade 2013 - 2022", available online at https://solarsystem.nasa.gov/2013decadal/) serves as a roadmap for activities to be pursued by the Planetary Science Division of NASA's Science Mission Directorate. This document outlines roughly 200 key research areas and questions in chapters covering different parts of the solar system (e.g., Mars, Small Bodies, etc.). We have reviewed the Decadal Survey to assess whether any of the key questions can be addressed by high altitude balloon-borne payloads. Although some questions can only be answered by in situ experiments, we found that approximately one quarter of the key questions were well suited to balloon payloads. In many of those cases, balloons were competitive or superior to other existing facilities, including HST, SOFIA or Keck telescopes. We will present specific telescope and instrument bench designs that are capable of addressing key questions in the Decadal Survey. The instrument bench takes advantage of two of the main benefits of high-altitude observations: diffraction-limited imaging in visible and UV wavelengths and unobstructed spectroscopy in near-IR (1 - 5 microns) wavelengths. Our optical prescription produces diffraction-limited PSFs in both visible and IR beams. We will discuss pointing and thermal stability, two of the main challenges facing a balloon-borne telescope.

  15. Temporomandibular chronic dislocation: The long-standing condition

    PubMed Central

    Puche-Torres, Miguel; Iglesias-Gimilio, Maria-Eugenia

    2016-01-01

    Background The temporomandibular joint (TMJ) dislocation can be categorised into three groups: acute, habitual or recurrent and long-standing. The long-standing or protracted lower jaw dislocation refers to a condition that persists for more than one month without reduction. There are a great variety of methods for its treatment, from the manual or non-surgical, to surgical ones like the indirect approach (conservative surgical approach) and direct approach (open joint). Additional procedures in unsuccessful cases may include extra-articular orthognathic techniques to correct a malocclusion until joint replacement. Material and Methods We report four new cases with a minimum of 6 weeks dislocation who were seen since 1995 to 2015 in the Maxillofacial Department of the Clínico Hospital (Valencia, Spain), in which the mean age was 57.5 years. Most of them were bilateral and the gender was predominantly female. Additionally, we have reviewed the related literature. Results All of the cases were successfully treated and half of them required open surgery. Conclusions The report confirms the difficulty of the treatment and reaffirms the necessity to bear in mind the wide variety of methods available for the treatment of this pathology. We stress the difficulties associated with managing the treatment and of suggesting new guidelines. The best option still remains not to delay the diagnostic and to select the appropriate initial treatment. Key words:Temporomandibular luxation, TMJ dislocation, protracted dislocation, long-standing dislocation. PMID:27694782

  16. Experimental approaches for addressing fundamental biological questions in living, functioning cells with single molecule precision.

    PubMed

    Lenn, Tchern; Leake, Mark C

    2012-06-01

    In recent years, single molecule experimentation has allowed researchers to observe biological processes at the sensitivity level of single molecules in actual functioning, living cells, thereby allowing us to observe the molecular basis of the key mechanistic processes in question in a very direct way, rather than inferring these from ensemble average data gained from traditional molecular and biochemical techniques. In this short review, we demonstrate the impact that the application of single molecule bioscience experimentation has had on our understanding of various cellular systems and processes, and the potential that this approach has for the future to really address very challenging and fundamental questions in the life sciences.

  17. Restoration of Long Standing Traumatized Teeth: A Case Report

    PubMed Central

    Kadkol, Prasanna Kumar; Reddy, K. Veera Kishore Kumar; Ainapur, Raghavendra

    2015-01-01

    Children are uniquely susceptible to craniofacial trauma. Injuries to the teeth occur often as a result of falls and sport activities. The pulp often gets infected after dental trauma resulting in to numerous complications. The authors present a case report of successful restoration of traumatized teeth with open apex which were weakened due to long standing infection and internal resorption. Initially antibiotic combination of 3- mix was used to disinfect the root canals. One tooth is treated with conventional endodontic treatment and the other tooth with open apex and perforation is managed by MTA apexification followed by canal reinforcement using glass ionomer cement and fiber reinforced composite post. Core build up is done using light cure composite resin followed by aesthetic crowns. The patient also presented with the peg shaped lateral incisors, which were built to an aesthetic appearance using light cure composite resins. PMID:26436062

  18. To Address or Not to Address the Violent Past in the Classroom? That Is the Question in Côte D'ivoire

    ERIC Educational Resources Information Center

    Kuppens, Line; Langer, Arnim

    2016-01-01

    In the aftermath of violent conflict, divided societies have to answer the important question of whether, when and how to address their country's violent past within their educational system. Whereas some scholars within the field of peace education and transitional justice argue that addressing the violent past in the classroom is important for…

  19. Coconut Atrium in Long-Standing Rheumatic Valvular Heart Disease

    PubMed Central

    Onishi, Takahisa; Idei, Yuka; Otsui, Kazunori; Iwata, Sachiyo; Suzuki, Atsushi; Ozawa, Toru; Domoto, Koji; Takei, Asumi; Inamoto, Shinya; Inoue, Nobutaka

    2015-01-01

    Patient: Male, 76 Final Diagnosis: Rheumatic valvular heart disease Symptoms: Breathlessness and leg edema Medication: — Clinical Procedure: Medical treatment for heart failure Specialty: Cardiology Objective: Rare disease Background: Complete calcification of the left atrium (LA) is called “coconut atrium”, which decreases the compliance of LA, leading to the elevation of LA pressure that is transmitted to the right-side of the heart. The pathogenesis of LA calcification in patients with rheumatic heart disease is unknown; however, possible mechanisms include chronic strain force in the atrial wall and inflammation. We report here a patient with long-standing rheumatic valvular heart disease with coconut atrium. Case Report: A 76-year-old man presented with breathlessness and leg edema due to right-sided heart failure. He was diagnosed with rheumatic fever at 8 years of age. Mitral commissurotomy and the mitral and aortic valve replacement were previously performed to treat mitral and aortic valvular stenosis. The profile view of the chest X-ray indicated a diffuse calcified outline of the LA wall. A transthoracic echocardiogram revealed pulmonary hyper-tension and dilatation of both atria. Moreover, computed tomography showed nearly circumferential calcification of the LA wall. Despite intense medical treatment, he succumbed to heart failure. An autopsy demonstrated that the LA was markedly dilated, its wall was calcified, and its appearance was similar to the surface of an atherosclerotic aorta. Microscopic examination revealed intensive calcification in the endocardium. Minimal accumulation of inflammatory cells was noted. Although slight fibrosis was observed, the cardiac musculature was preserved. Conclusions: To the best of our knowledge, this is the first report that identifies the histological changes of LA calcification associated with long-standing rheumatic valvular heart disease. PMID:25819539

  20. Early Parental Positive Behavior Support and Childhood Adjustment: Addressing Enduring Questions with New Methods

    PubMed Central

    Waller, Rebecca; Gardner, Frances; Dishion, Thomas; Sitnick, Stephanie L.; Shaw, Daniel S.; Winter, Charlotte E.; Wilson, Melvin

    2016-01-01

    A large literature provides strong empirical support for the influence of parenting on child outcomes. The current study addresses enduring research questions testing the importance of early parenting behavior to children’s adjustment. Specifically, we developed and tested a novel multi-method observational measure of parental positive behavior support at age 2. Next, we tested whether early parental positive behavior support was related to child adjustment at school age, within a multi-agent and multi-method measurement approach and design. Observational and parent-reported data from mother–child dyads (N = 731; 49 percent female) were collected from a high-risk sample at age 2. Follow-up data were collected via teacher report and child assessment at age 7.5. The results supported combining three different observational methods to assess positive behavior support at age 2 within a latent factor. Further, parents’ observed positive behavior support at age 2 predicted multiple types of teacher-reported and child-assessed problem behavior and competencies at 7.5 years old. Results supported the validity and predictive capability of a multi-method observational measure of parenting and the importance of a continued focus on the early years within preventive interventions. PMID:26997757

  1. Mars 2001 Mission: Addressing Scientific Questions Regarding the Characteristics and Origin of Local Bedrock and Soil

    NASA Technical Reports Server (NTRS)

    Saunders, R. S.; Arvidson, R. E.; Weitz, C. M.; Marshall, J.; Squyres, S. W.; Christensen, P. R.; Meloy, T.; Smith, P.

    1999-01-01

    The Mars Surveyor Program 2001 Mission will carry instruments on the orbiter, lander and rover that will support synergistic observations and experiments to address important scientific questions regarding the local bedrock and soils. The martian surface is covered in varying degrees by fine materials less than a few mms in size. Viking and Pathfinder images of the surface indicate that soils at those sites are composed of fine particles. Wheel tracks from the Sojourner rover suggest that soil deposits are composed of particles <40 mm. Viking images show that dunes are common in many areas on Mars and new MOC images indicate that dunes occur nearly everywhere. Dunes on Mars are thought to be composed of 250-500 microns particles based upon Viking IRTM data and Mars wind tunnel experiments. If martian dunes are composed of sand particles > 100 microns and soils are dominated by <10 micron particles, then where are the intermediate grain sizes? Have they been wom away through prolonged transport over the eons? Were they never generated to begin with? Or are they simply less easy to identify because do they not form distinctive geomorphic features such as dunes or uniform mantles that tend to assume superposition in the soil structure?

  2. Early Parental Positive Behavior Support and Childhood Adjustment: Addressing Enduring Questions with New Methods.

    PubMed

    Waller, Rebecca; Gardner, Frances; Dishion, Thomas; Sitnick, Stephanie L; Shaw, Daniel S; Winter, Charlotte E; Wilson, Melvin

    2015-05-01

    A large literature provides strong empirical support for the influence of parenting on child outcomes. The current study addresses enduring research questions testing the importance of early parenting behavior to children's adjustment. Specifically, we developed and tested a novel multi-method observational measure of parental positive behavior support at age 2. Next, we tested whether early parental positive behavior support was related to child adjustment at school age, within a multi-agent and multi-method measurement approach and design. Observational and parent-reported data from mother-child dyads (N = 731; 49 percent female) were collected from a high-risk sample at age 2. Follow-up data were collected via teacher report and child assessment at age 7.5. The results supported combining three different observational methods to assess positive behavior support at age 2 within a latent factor. Further, parents' observed positive behavior support at age 2 predicted multiple types of teacher-reported and child-assessed problem behavior and competencies at 7.5 years old. Results supported the validity and predictive capability of a multi-method observational measure of parenting and the importance of a continued focus on the early years within preventive interventions.

  3. A meta-analysis of personality and workplace safety: addressing unanswered questions.

    PubMed

    Beus, Jeremy M; Dhanani, Lindsay Y; McCord, Mallory A

    2015-03-01

    [Correction Notice: An Erratum for this article was reported in Vol 100(2) of Journal of Applied Psychology (see record 2015-08139-001). Table 3 contained formatting errors. Minus signs used to indicate negative statistical estimates within the table were inadvertently changed to m-dashes. All versions of this article have been corrected.] The purpose of this meta-analysis was to address unanswered questions regarding the associations between personality and workplace safety by (a) clarifying the magnitude and meaning of these associations with both broad and facet-level personality traits, (b) delineating how personality is associated with workplace safety, and (c) testing the relative importance of personality in comparison to perceptions of the social context of safety (i.e., safety climate) in predicting safety-related behavior. Our results revealed that whereas agreeableness and conscientiousness were negatively associated with unsafe behaviors, extraversion and neuroticism were positively associated with them. Of these traits, agreeableness accounted for the largest proportion of explained variance in safety-related behavior and openness to experience was unrelated. At the facet level, sensation seeking, altruism, anger, and impulsiveness were all meaningfully associated with safety-related behavior, though sensation seeking was the only facet that demonstrated a stronger relationship than its parent trait (i.e., extraversion). In addition, meta-analytic path modeling supported the theoretical expectation that personality's associations with accidents are mediated by safety-related behavior. Finally, although safety climate perceptions accounted for the majority of explained variance in safety-related behavior, personality traits (i.e., agreeableness, conscientiousness, neuroticism) still accounted for a unique and substantive proportion of the explained variance. Taken together, these results substantiate the value of considering personality traits as key

  4. Questions

    ERIC Educational Resources Information Center

    Kuntz, Haley

    2007-01-01

    A canoe trip guide for young people gets used to the never-ending flow of questions. Kids are constantly inquiring about how many kilometres have been traveled that day, how many kilometres to go that day, what is for dinner, and when the next set of moving water is coming up. With kids, the questions are endless. Questions often are used as a…

  5. Aviation Security: Slow Progress in Addressing Long-Standing Screener Performance Problems

    DTIC Science & Technology

    2007-11-02

    aviation security , in particular airport screeners. Securing an air transportation system the size of this nation’s-with hundreds of airports, thousands of aircraft, and tens of thousands of flights daily carrying millions of passengers and pieces of baggage-is a difficult task. Events over the past decade have shown that the threat of terrorism against the United States is an ever-present danger. Aviation is an attractive target for terrorists, and because the air transportation system is critical to the nation’s well-being, protecting it is an important

  6. Some Long-Standing and Emerging Research Lines in Africa

    ERIC Educational Resources Information Center

    Serpell, Robert; Marfo, Kofi

    2014-01-01

    Early research on child development in Africa was dominated by expatriates and was primarily addressed to the topics of testing the cross-cultural validity of theories developed "in the West," and the search for universals. After a brief review of the outcome of that research, we propose two additional types of motivation that seem…

  7. From experience to definition: addressing the question 'what is qualitative research?'.

    PubMed

    Smythe, Liz; Giddings, Lynne S

    2007-07-01

    Most health professionals today have heard of 'qualitative research' but many remain confused as to what it is and how to go about doing it. In this paper, two experienced qualitative researchers become engaged in conversation exploring the question 'what is qualitative research?' Lynne Giddings and Liz Smythe are Associate Professors in the Faculty of Health & Environmental Sciences at the Auckland University of Technology. They engage a reader in exploring issues such as: What might draw you to qualitative research? How does qualitative research make a difference to practice? How can reading a qualitative research article inform practice? From a qualitative perspective, what is 'truth'? How many participants? What happens to the data? What about the bias of the researcher? Can qualitative findings be trusted? Stories and exemplars are used to highlight the processes and issues involved in undertaking a qualitative research study.

  8. Some long-standing and emerging research lines in Africa.

    PubMed

    Serpell, Robert; Marfo, Kofi

    2014-01-01

    Early research on child development in Africa was dominated by expatriates and was primarily addressed to the topics of testing the cross-cultural validity of theories developed "in the West," and the search for universals. After a brief review of the outcome of that research, we propose two additional types of motivation that seem important to us as African researchers begin to take the lead in articulating research agendas for the study of child development in Africa: articulating the contextual relevance and practical usefulness of developmental psychology in Africa; and making developmental psychology intelligible to local audiences. We highlight two major challenges for African societies in this era that call for attention by the emerging field of African child development research: linguistic hegemony and its effects on research and schooling; and the process of indigenization. We end with a preview of chapters in the rest of the volume.

  9. The Swimming Ammonite: How Computed Tomography can Address Questions of Functional Morphology

    NASA Astrophysics Data System (ADS)

    Lemanis, Robert; Hoffmann, Rene; Zachow, Stefan

    2014-05-01

    has strong potential to address the controversial life-habits of adult ammonites through the study of the buoyant properties of the phragmocone and the structural properties of the shell. The implications for palaeobiology are clear, however the understanding of ammonite life-habits is also important for utilization as archives for palaeoenvironmetal/geochemical data.

  10. A long-standing hyperglycaemic condition impairs skin barrier by accelerating skin ageing process.

    PubMed

    Park, Hwa-Young; Kim, Jae-Hong; Jung, Minyoung; Chung, Choon Hee; Hasham, Rosnani; Park, Chang Seo; Choi, Eung Ho

    2011-12-01

    Uncontrolled chronic hyperglycaemia including type 2 diabetes mellitus (DM) induces many skin problems related to chronic impaired skin barrier state. However, little is known about the skin barrier state of chronic hyperglycaemia patients, the dysfunction of which may be a major cause of their skin problems. In this study, we investigated whether a long-standing hyperglycaemic condition including type 2 DM impairs skin barrier homoeostasis in proportion to the duration and its pathomechanism. We utilized the Otsuka Long-Evans Tokushima Fatty (OLETF) rats as an animal model of long-standing hyperglycaemia and Long-Evans Tokushima Otsuka rats as a control strain. We confirmed that a long-standing hyperglycaemia delayed skin barrier homoeostasis, which correlated with haemoglobin A1c levels. OLETF rats as a long-standing hyperglycaemia model exhibited decreased epidermal lipid synthesis and antimicrobial peptide expression with increasing age. Decreased epidermal lipid synthesis accounted for decreased lamellar body production. In addition, OLETF rats had significantly higher serum levels of advanced glycation end products (AGEs) and elevated levels of the receptor for AGE in the epidermis. A long-standing hyperglycaemic condition impairs skin barrier function including permeability and antimicrobial barriers by accelerating skin ageing process in proportion to the duration of hyperglycaemia, which could be a major pathophysiology underlying cutaneous complications of DM.

  11. Addressing Consumer Questions.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    It seems people either have very strong thoughts and opinions on food or they could care less as long as food is available to feed them and their families. With the current economy, many individuals are examining food choices more closely to ensure the greatest nutrition for their families at the l...

  12. Eccrine Syringofibroadenoma in a Patient with Long-Standing Exfoliative Dermatitis

    PubMed Central

    Ko, Eun Jung; Park, Kui Young; Kwon, Hyun Jung; Shim, Joo Hyun

    2016-01-01

    Eccrine syringofibroadenoma (ESFA) is a rare benign cutaneous adnexal lesion characterized by a hyperplastic epithelium and eccrine ductal differentiation. In the present case, a 73-year-old Korean male presented with symmetrical numerous widespread, pinkish nodules with a cobblestone appearance over both legs for 2 years. He had a history of generalized erythematous scaly patches over his entire body for 20 years. On histopathologic findings, diagnosis of ESFA was confirmed. Our unusual and interesting case emphasizes the first report described one case in which multiple cobblestone like ESFAs arising from long-standing exfoliative dermatitis. PMID:27904279

  13. Eccrine Syringofibroadenoma in a Patient with Long-Standing Exfoliative Dermatitis.

    PubMed

    Ko, Eun Jung; Park, Kui Young; Kwon, Hyun Jung; Shim, Joo Hyun; Seo, Seong Jun

    2016-12-01

    Eccrine syringofibroadenoma (ESFA) is a rare benign cutaneous adnexal lesion characterized by a hyperplastic epithelium and eccrine ductal differentiation. In the present case, a 73-year-old Korean male presented with symmetrical numerous widespread, pinkish nodules with a cobblestone appearance over both legs for 2 years. He had a history of generalized erythematous scaly patches over his entire body for 20 years. On histopathologic findings, diagnosis of ESFA was confirmed. Our unusual and interesting case emphasizes the first report described one case in which multiple cobblestone like ESFAs arising from long-standing exfoliative dermatitis.

  14. Restoration of Glucose Counterregulation by Islet Transplantation in Long-standing Type 1 Diabetes.

    PubMed

    Rickels, Michael R; Fuller, Carissa; Dalton-Bakes, Cornelia; Markmann, Eileen; Palanjian, Maral; Cullison, Kevin; Tiao, Janice; Kapoor, Shiv; Liu, Chengyang; Naji, Ali; Teff, Karen L

    2015-05-01

    Patients with long-standing type 1 diabetes (T1D) may exhibit defective glucose counterregulation and impaired hypoglycemia symptom recognition that substantially increase their risk for experiencing severe hypoglycemia. The purpose of this study was to determine whether intrahepatic islet transplantation improves endogenous glucose production (EGP) in response to hypoglycemia in T1D patients experiencing severe hypoglycemia. We studied longitudinally subjects (n = 12) with ∼30 years, disease duration before and 6 months after intrahepatic islet transplantation using stepped hyperinsulinemic-hypoglycemic and paired hyperinsulinemic-euglycemic clamps with infusion of 6,6-(2)H2-glucose and compared the results with those from a nondiabetic control group (n = 8). After islet transplantation, HbA1c was normalized, and time spent while hypoglycemic (<70 mg/dL) was nearly abolished as indicated by continuous glucose monitoring. In response to insulin-induced hypoglycemia, C-peptide (absent before transplant) was appropriately suppressed, glucagon secretion was recovered, and epinephrine secretion was improved after transplantation. Corresponding to these hormonal changes, the EGP response to insulin-induced hypoglycemia, which was previously absent, was normalized after transplantation, with a similar effect seen for autonomic symptoms. Because the ability to increase EGP is ultimately required to circumvent the development of hypoglycemia, these results provide evidence that intrahepatic islet transplantation can restore glucose counterregulation in long-standing T1D and support its consideration as treatment for patients with hypoglycemia unawareness experiencing severe hypoglycemia.

  15. Strategies to Address Recruiting and Retention Issues in the Military (Strategies pour aborder les questions de recrutement et de fidelisation dans les armees)

    DTIC Science & Technology

    2009-10-01

    Oct 2009 Strategies to Address Recruiting and Retention Issues in the Military (Stratégies pour aborder les questions de recrutement et de...les questions de recrutement et de fidélisation dans les armées) The material in this publication was assembled to support a Special Course under...HFM-180 Stratégies pour aborder les questions de recrutement et de fidélisation dans les armées (RTO-EN-HFM-180) Synthèse L’objectif des

  16. Introducing Astrophysics and Cosmology as Part of Multidisciplinary Approaches to Liberal Arts Courses Addressing "The Big Questions" of Human Experience

    NASA Astrophysics Data System (ADS)

    Wesney, J. C.

    2012-08-01

    There is an opportunity to bring college students to the exploration of the grandeur and wonder of the universe through the design and crafting of courses for the university and liberal arts curricula that would develop multidisciplinary perspectives within the frames of reference of astrophysics and cosmology. There is broad interest within colleges and universities to provide courses that examine "The Big Questions" of human experience from a variety of perspectives. The study of the history of discoveries and insights that we have gained through the development of astrophysics and cosmology provides course options for students to use to explore these questions. Such hybrid courses enable students to approach the questions of origins, human existence, appreciation of the natural world, appreciation of the universe at large, and the significance of our evolving comprehension of the universe from a variety of disciplinary perspectives, including those that border on the astrophysical and cosmological domains. There are within such courses opportunities to examine historical, philosophical, theological, and cultural perspectives as they intersect with our scientific understanding of where and who we are. The first of these courses at Sacred Heart University has been developed and presented for the past two years as part of the new Core Curriculum. The development of that course, entitled The Journey in the Physical Universe, will be discussed, and insights will be shared.

  17. The long-lasting now: disorganization in subjective time in long-standing pain.

    PubMed

    Hellström, C; Carlsson, S G

    1996-12-01

    This paper presents a phenomenological-hermeneutical case study on long-standing pain (LP), a public health problem of great importance. Although there has been intensive research interest in this phenomenon, most studies have been based on traditional medical and cognitive-behavioral approaches. Our thesis is that new frames of reference can provide additional heuristic insights. The phenomenon of LP shows a strong association with existential factors. Our case study focuses on the meaning-structure of lived temporality, a fundamental existential constituent in the lifeworld of the pain patient. A series of in-depth interviews with four subjects showed that lived temporality is disrupted in pain experience, causing a disorganization of the patient's being in the world. The results generate several hypotheses about implications for time estimation in pain experience.

  18. Statistical Physics Methods Provide the Exact Solution to a Long-Standing Problem of Genetics.

    PubMed

    Samal, Areejit; Martin, Olivier C

    2015-06-12

    Analytic and computational methods developed within statistical physics have found applications in numerous disciplines. In this Letter, we use such methods to solve a long-standing problem in statistical genetics. The problem, posed by Haldane and Waddington [Genetics 16, 357 (1931)], concerns so-called recombinant inbred lines (RILs) produced by repeated inbreeding. Haldane and Waddington derived the probabilities of RILs when considering two and three genes but the case of four or more genes has remained elusive. Our solution uses two probabilistic frameworks relatively unknown outside of physics: Glauber's formula and self-consistent equations of the Schwinger-Dyson type. Surprisingly, this combination of statistical formalisms unveils the exact probabilities of RILs for any number of genes. Extensions of the framework may have applications in population genetics and beyond.

  19. Statistical Physics Methods Provide the Exact Solution to a Long-Standing Problem of Genetics

    NASA Astrophysics Data System (ADS)

    Samal, Areejit; Martin, Olivier C.

    2015-06-01

    Analytic and computational methods developed within statistical physics have found applications in numerous disciplines. In this Letter, we use such methods to solve a long-standing problem in statistical genetics. The problem, posed by Haldane and Waddington [Genetics 16, 357 (1931)], concerns so-called recombinant inbred lines (RILs) produced by repeated inbreeding. Haldane and Waddington derived the probabilities of RILs when considering two and three genes but the case of four or more genes has remained elusive. Our solution uses two probabilistic frameworks relatively unknown outside of physics: Glauber's formula and self-consistent equations of the Schwinger-Dyson type. Surprisingly, this combination of statistical formalisms unveils the exact probabilities of RILs for any number of genes. Extensions of the framework may have applications in population genetics and beyond.

  20. Vocal cord immobility caused by the long-standing impaction of a fishbone in the hypopharynx.

    PubMed

    Hung, Chung-Ching; Lee, Jih-Chin; Hsiao, Li-Chun; Lin, Yaoh-Shiang

    2009-01-01

    Vocal cord immobility is a rare presentation of an impacted fishbone in the pharynx. The mechanisms can be classified into either mechanical articular fixation or direct/indirect neuropathy of the recurrent laryngeal nerve. We report a case of vocal cord immobility secondary to long-standing impaction of a fishbone in the hypopharynx for at least 9 months. The diagnosis was made by computed tomography (CT) and rigid laryngoscopy because no reliable history was available. The cricoarytenoid joint was not fixed and the function of the vocal cords returned one month after removal of the fishbone. The mechanism of the vocal cord immobility was an injury to the recurrent laryngeal nerve due to the chronic inflammatory reaction in the paraglottic space.

  1. Interleukin 18 maintains a long-standing inflammation in coeliac disease patients

    PubMed Central

    León, A J; Garrote, J A; Blanco-Quirós, A; Calvo, C; Fernández-Salazar, L; Del Villar, A; Barrera, A; Arranz, E

    2006-01-01

    Dietary gluten induces an early response in the intestine of coeliac disease patients (CD), within a few hours, and this is driven by high levels of proinflammatory cytokines, including IFNγ and IL-15, as has been thoroughly shown by gluten stimulation of biopsy explants. Our aim was to identify the immune mediators involved in the long-standing inflammation in untreated CD patients at diagnosis. mRNA and protein levels of TNFα, IL-12(p35), IL-12(p40), IL-15, IL-18 and IL-23(p19) were quantified in biopsies from active CD patients, CD patients on a gluten-free diet (GFD), healthy controls, and patients with non-CD inflammation and mild histological changes in the intestine. Biopsies from CD patients on a GFD were also stimulated in vitro with gliadin, and protein expression of IL-15 and IL-18 was analysed. Levels of IL-12 and IL-23 mRNA are nearly absent, and TNFα levels remain unchanged among different groups. Both the active and inactive forms of IL-18 protein have been found in all samples from active CD, and protein expression was only localized within the crypts. Levels of IL-15 mRNA remain unchanged, and protein expression, localized within the lamina propria, is found in a small number of samples. In vitro stimulation with gluten induces the expression of IL-15 and IL-18. In active CD, the early response following gluten intake characterized by high IFNγ levels is driven by IL-18, and probably IL-15, and this alternates with periods of long-standing inflammation with moderate IFNγ levels, maintained by IL-18 alone. PMID:17100768

  2. How much detail and accuracy is required in plant growth sub-models to address questions about optimal management strategies in agricultural systems?

    PubMed Central

    Renton, Michael

    2011-01-01

    Background and aims Simulations that integrate sub-models of important biological processes can be used to ask questions about optimal management strategies in agricultural and ecological systems. Building sub-models with more detail and aiming for greater accuracy and realism may seem attractive, but is likely to be more expensive and time-consuming and result in more complicated models that lack transparency. This paper illustrates a general integrated approach for constructing models of agricultural and ecological systems that is based on the principle of starting simple and then directly testing for the need to add additional detail and complexity. Methodology The approach is demonstrated using LUSO (Land Use Sequence Optimizer), an agricultural system analysis framework based on simulation and optimization. A simple sensitivity analysis and functional perturbation analysis is used to test to what extent LUSO's crop–weed competition sub-model affects the answers to a number of questions at the scale of the whole farming system regarding optimal land-use sequencing strategies and resulting profitability. Principal results The need for accuracy in the crop–weed competition sub-model within LUSO depended to a small extent on the parameter being varied, but more importantly and interestingly on the type of question being addressed with the model. Only a small part of the crop–weed competition model actually affects the answers to these questions. Conclusions This study illustrates an example application of the proposed integrated approach for constructing models of agricultural and ecological systems based on testing whether complexity needs to be added to address particular questions of interest. We conclude that this example clearly demonstrates the potential value of the general approach. Advantages of this approach include minimizing costs and resources required for model construction, keeping models transparent and easy to analyse, and ensuring the model

  3. DNA methylation and triplet repeat stability: New proposals addressing actual questions on the CGG repeat of fragile X syndrome

    SciTech Connect

    Woehrle, D.; Schwemmle, S.; Steinbach, P.

    1996-08-09

    Methylation of expanded CGG repeats in the FMR1 gene may well have different consequences. One is that methylation, extending into upstream regulatory elements, could lead to gene inactivation. Another effect of methylation, which we have obtained evidence for, could be stabilization of the repeat sequence and even prevention of premutations from expansion to full mutation. The full mutation of the fragile X syndrome probably occurs in an early transitional stage of embryonic development. The substrate is a maternally inherited premutation. The product usually is a mosaic pattern of full mutations detectable in early fetal life. These full mutation patterns are mitotically stable as, for instance, different somatic tissues of full mutation fetuses show identical mutation patterns. This raised the following questions: What triggers repeat expansion in that particular stage of development and what causes subsequent mitotic stability of expanded repeats? 21 refs., 1 fig.

  4. Modeling the Cerebellar Microcircuit: New Strategies for a Long-Standing Issue

    PubMed Central

    D’Angelo, Egidio; Antonietti, Alberto; Casali, Stefano; Casellato, Claudia; Garrido, Jesus A.; Luque, Niceto Rafael; Mapelli, Lisa; Masoli, Stefano; Pedrocchi, Alessandra; Prestori, Francesca; Rizza, Martina Francesca; Ros, Eduardo

    2016-01-01

    The cerebellar microcircuit has been the work bench for theoretical and computational modeling since the beginning of neuroscientific research. The regular neural architecture of the cerebellum inspired different solutions to the long-standing issue of how its circuitry could control motor learning and coordination. Originally, the cerebellar network was modeled using a statistical-topological approach that was later extended by considering the geometrical organization of local microcircuits. However, with the advancement in anatomical and physiological investigations, new discoveries have revealed an unexpected richness of connections, neuronal dynamics and plasticity, calling for a change in modeling strategies, so as to include the multitude of elementary aspects of the network into an integrated and easily updatable computational framework. Recently, biophysically accurate “realistic” models using a bottom-up strategy accounted for both detailed connectivity and neuronal non-linear membrane dynamics. In this perspective review, we will consider the state of the art and discuss how these initial efforts could be further improved. Moreover, we will consider how embodied neurorobotic models including spiking cerebellar networks could help explaining the role and interplay of distributed forms of plasticity. We envisage that realistic modeling, combined with closed-loop simulations, will help to capture the essence of cerebellar computations and could eventually be applied to neurological diseases and neurorobotic control systems. PMID:27458345

  5. Psychological stress with long-standing allergic dermatitis causes psychodermatological conditions in mice.

    PubMed

    Kitagaki, Hideki; Hiyama, Hidetaka; Kitazawa, Toshiki; Shiohara, Tetsuo

    2014-06-01

    Psychological factors have long been assumed to be involved in the pathogenesis of allergic skin diseases. The effects of psychological stress on allergic contact dermatitis (ACD) have been experimentally well investigated; however, the effects of ACD on stress responses are largely unknown. Here, we report that preceding chronic ACD dramatically affects the behavioral and physiological stress responses to social isolation (a psychological stressor). In male BALB/c mice, social isolation combined with long-standing (>2 months) ACD by repeated hapten application caused characteristic symptoms, including chronic dermatitis from persistent self-scratching, behavioral changes related to fear/anxiety, and elevated serum IgE levels. The symptoms were maintained by social isolation alone without further hapten application after the onset, and were improved by resocialization. Treatment with topical corticosteroids exacerbated chronic scratch dermatitis, whereas it was effective for chronic ACD. These results show that the symptoms represent a de novo development of a specific disease state and not a mere exacerbation of a preexisting allergic inflammation. With this experimental protocol, similar results were obtained in several other strains of mice. This murine model provides a tool for investigating the pathogenesis and treatment of allergic skin disease with psychodermatological aspects.

  6. Optimizing Inspection Parameters for Long Stand-Off Detection of SNM

    SciTech Connect

    Johnson, Erik; Blackburn, Brandon; Hynes, Michael; Hausladen, Paul

    2011-12-13

    Detection of special nuclear material (SNM) at extended ranges (>100 m) through the utilization of high energy (>20 MeV) bremsstrahlung photons requires optimizing the structure and interrelation of irradiation (beam-on) and detection (counting) periods. Conventional inspection schemes at lower energies and smaller distances primarily operate by pulsing an accelerator at frequencies of 0.1-1 kHz while collecting emitted radiation from the target under inspection for the few milliseconds in between pulses. Simulation and experimental results for long stand-off scenarios with source photons >20 MeV, however, indicate that two primary phenomena--(1) induced photoneutrons in proximity to the accelerator and (2) beam induced activation of air and soil--preclude the use of conventional inspection schemes. By considering the time structure and magnitude of the beam-induced photon and neutron backgrounds, signals of interest from the target, and natural backgrounds, inspection schemes have been developed to maximize signal to noise ratios (SNR). Analysis of the data indicates that the highest SNR values are found with short (2-5 s) irradiations followed by a 1-2 s period of collecting emitted neutron and photon signatures.

  7. Experimental pressure-temperature phase diagram of boron: resolving the long-standing enigma

    PubMed Central

    Parakhonskiy, Gleb; Dubrovinskaia, Natalia; Bykova, Elena; Wirth, Richard; Dubrovinsky, Leonid

    2011-01-01

    Boron, discovered as an element in 1808 and produced in pure form in 1909, has still remained the last elemental material, having stable natural isotopes, with the ground state crystal phase to be unknown. It has been a subject of long-standing controversy, if α-B or β-B is the thermodynamically stable phase at ambient pressure and temperature. In the present work this enigma has been resolved based on the α-B-to- β-B phase boundary line which we experimentally established in the pressure interval of ∼4 GPa to 8 GPa and linearly extrapolated down to ambient pressure. In a series of high pressure high temperature experiments we synthesised single crystals of the three boron phases (α-B, β-B, and γ-B) and provided evidence of higher thermodynamic stability of α-B. Our work opens a way for reproducible synthesis of α-boron, an optically transparent direct band gap semiconductor with very high hardness, thermal and chemical stability. PMID:22355614

  8. Development of Graves’ disease after long-standing hypothyroidism on treatment, with acute toxicity to thionamides and lithium

    PubMed Central

    Gupta, Yashdeep; Singh, Sandeep; Ammini, Ariachery C

    2012-01-01

    Thyroid hyperfunction in a patient with long-standing hypothyroidism is uncommon. Here, we describe and discuss the unusual scenario of development of severe skin rash to carbimazole, with subsequent acute toxicity to lithium in clinically indicated doses, in a patient who manifested hyperthyroidism after being on treatment for hypothyroidism for 7 years. PMID:22854236

  9. A comprehensive approach to long-standing facial paralysis based on lengthening temporalis myoplasty.

    PubMed

    Labbè, D; Bussu, F; Iodice, A

    2012-06-01

    Long-standing peripheral monolateral facial paralysis in the adult has challenged otolaryngologists, neurologists and plastic surgeons for centuries. Notwithstanding, the ultimate goal of normality of the paralyzed hemi-face with symmetry at rest, and the achievement of a spontaneous symmetrical smile with corneal protection, has not been fully reached. At the beginning of the 20(th) century, the main options were neural reconstructions including accessory to facial nerve transfer and hypoglossal to facial nerve crossover. In the first half of the 20(th) century, various techniques for static correction with autologous temporalis muscle and fascia grafts were proposed as the techniques of Gillies (1934) and McLaughlin (1949). Cross-facial nerve grafts have been performed since the beginning of the 1970s often with the attempt to transplant free-muscle to restore active movements. However, these transplants were non-vascularized, and further evaluations revealed central fibrosis and minimal return of function. A major step was taken in the second half of the 1970s, with the introduction of microneurovascular muscle transfer in facial reanimation, which, often combined in two steps with a cross-facial nerve graft, has become the most popular option for the comprehensive treatment of long-standing facial paralysis. In the second half of the 1990s in France, a regional muscle transfer technique with the definite advantages of being one-step, technically easier and relatively fast, namely lengthening temporalis myoplasty, acquired popularity and consensus among surgeons treating facial paralysis. A total of 111 patients with facial paralysis were treated in Caen between 1997 and 2005 by a single surgeon who developed 2 variants of the technique (V1, V2), each with its advantages and disadvantages, but both based on the same anatomo-functional background and aim, which is transfer of the temporalis muscle tendon on the coronoid process to the lips. For a comprehensive

  10. Addressing Consumer Questions and Concerns

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Food can be a touchy subject. It seems people either have very strong thoughts and opinions on food or they could care less as long as food is available to feed them and their families. With the current economic environment, many individuals are examining the food choices more closely to ensure t...

  11. Predicted Values for Spirometry may Underestimate Long-Standing Asthma Severity

    PubMed Central

    Sposato, Bruno

    2016-01-01

    Background: Asthma may show an accelerated lung function decline. Asthmatics, although having FEV1 and FEV1/VC (and z-scores) higher than the lower limit of normality, may show a significant FEV1 decline when compared to previous measurements. We assessed how many asymptomatic long-standing asthmatics (LSA) with normal lung function showed a significant FEV1 decline when an older FEV1 was taken as reference point. Methods: 46 well-controlled LSA (age: 48.8±12.1; 23 females) with normal FEV1 and FEV1/VC according to GLI2012 references (FEV1: 94.8±10.1%, z-score:-0.38±0.79; FEV1/VC: 79.3±5.2, z-score:-0.15±0.77) were selected. We considered FEV1 decline, calculated by comparing the latest value to one at least five years older or to the highest predicted value measured at 21 years for females and 23 for males. A FEV1 decline >15% or 30 ml/years was regarded as pathological. Results: When comparing the latest FEV1 to an at least 5-year-older one (mean 8.1±1.4 years between 2 measurements), 14 subjects (30.4%) showed a FEV1 decline <5% (mean: -2.2±2.6%), 19 (41.3%) had a FEV1 5-15% change (mean: -9.2±2.5%) and 13 (28.3%) a FEV1 decrease>15% (mean: -18.3±2.4). Subjects with a FEV1 decline>30 ml/year were 28 (60.8%). When using the highest predicted FEV1 as reference point and declines were corrected by subtracting the physiological decrease, 6 (13%) patients showed a FEV1 decline higher than 15%, whereas asthmatics with a FEV1 loss>30 ml/year were 17 (37%). Conclusion: FEV1 decline calculation may show how severe asthma actually is, avoiding a bronchial obstruction underestimation and a possible under-treatment in lots of apparent “well-controlled” LSA with GLI2012-normal-range lung function values. PMID:28144365

  12. Squamous cell carcinoma developing in a long-standing case of tuberous xanthoma: An incident unreported hitherto

    PubMed Central

    Sancheti, Karan; Das, Anupam; Podder, Indrashis; Mohanty, Swosti; Gharami, Ramesh C.; Jash, Prabir K.

    2015-01-01

    Cutaneous squamous cell carcinoma, characterized by malignant transformation of normal epidermal keratinocyte is the second most common nonmelanoma skin cancer that has many predisposing factors. Tuberous xanthomas have not yet been reported as a predisposing factor. We report here the case of long-standing tuberous xanthoma in a middle-aged gentleman complicated by cutaneous squamous cell carcinoma, probably the first such report in the Indian literature. PMID:26904452

  13. Effects of a tartar control whitening dentifrice on tooth shade in a population with long-standing natural stain.

    PubMed

    Gerlach, R W; Barker, M L; Hyde, J D; Jones, M B; Cordero, R E

    2001-01-01

    Changing and whitening tooth color in people with long-standing tooth stain without excessive hard tissue abrasion may represent one of the more difficult challenges for whitening dentifrices. An eight-week clinical trial was conducted to evaluate change in tooth color by a silica-based, enamel-safe tartar control whitening dentifrice compared to a marketed baking soda dentifrice control. First, a screening exercise was conducted to identify individuals with long-standing extrinsic dental stain. This exercise targeted adults who reported "stained teeth" and coffee/tea drinking or smoking, but who had no recent history of dental prophylaxis. Targeted subjects were examined for stain (Lobene Index) and tooth shade/color (Vita). A total of 291 adults having extrinsic stain and discolored teeth were enrolled in the study. Subjects were randomized to one of the two treatment groups, and all dentifrice use was unsupervised. Tooth color was measured at 4 and 8 weeks from shade values collected from the 8 incisors, and averages were determined from a linear ordering of the shade guide. A total of 278 evaluable subjects completed the 8-week study. Overall, the tartar control whitening dentifrice group experienced an improvement in color, differing statistically from baseline (p < 0.001) and from the marketed control (p < 0.05). Safety profiles for the two dentifrices were generally similar. Among patients with long-standing extrinsic stain, use of the tartar control whitening dentifrice resulted in superior overall tooth shade and reduced maximum or worst color compared to the marketed baking soda dentifrice control.

  14. FOSTER CARE: Recent Legislation Helps States Focus on Finding Permanent Homes for Children, but Long-Standing Barriers Remain

    DTIC Science & Technology

    2002-06-01

    Office, Foster Care: Agencies Face Challenges Securing Stable Homes for Children of Substance Abusers, GAO/HEHS-98-182 (Washington, D.C.: Sept. 30, 1998...Approach. GAO/HEHS-99-8. Washington, D.C.: October 21, 1998. Foster Care: Agencies Face Challenges Securing Stable Homes for Children of Substance Abusers...Finding Permanent Homes for Children , but Long-Standing Barriers Remain GAO-02-585 Report Documentation Page Report Date 00JUN2002 Report Type N/A Dates

  15. Resolving a Long-Standing Ambiguity: the Non-Planarity of gauche-1,3-BUTADIENE Revealed by Microwave Spectroscopy

    NASA Astrophysics Data System (ADS)

    Martin-Drumel, Marie-Aline; McCarthy, Michael C.; Patterson, David; Eibenberger, Sandra; Buckingham, Grant; Baraban, Joshua H.; Ellison, Barney; Stanton, John F.

    2016-06-01

    The preferred conformation of cis-1,3-butadiene (CH_2=CH-CH=CH_2) has been of long-standing importance in organic chemistry because of its role in Diels-Alder transition states. The molecule could adopt a planar s-cis conformation, in favor of conjugations in the carbon chain, or a non-planar gauche conformation, as a result of steric interactions between the terminal H atoms. To resolve this ambiguity, we have now measured the pure rotational spectrum of this isomer in the microwave region, unambiguously establishing a significant inertial defect, and therefore a gauche conformation. Experimental measurements of gauche-1,3-butadiene and several of its isotopologues using cavity Fourier-transform microwave (FTMW) spectroscopy in a supersonic expansion and chirped-pulse FTMW spectroscopy in a 4 K buffer gas cell will be summarized, as will new quantum chemical calculations.

  16. Poverty and experiences of social devaluation: a qualitative interview study of 25 long-standing recipients of social security payments.

    PubMed

    Underlid, Kjell

    2005-07-01

    The purpose of this study is to explore experiences of social devaluation among people living in poverty. Twenty-five long-standing recipients of social security payments living in a city in Norway were interviewed. Most felt that people in their environment held low opinions of them regarding issues related to personality and moral integrity. Several factors play a role in the formation of such beliefs or assumptions: (a) impressions of prevailing views of the social category "the poor" and observations concerning devaluation of that category; (b) knowledge others are assumed to possess of the respondents' financial predicament; (c) perception of own social situation; (d) undesired behavior that signals low social status and low esteem; (e) actions by others that signal devaluation. Social devaluation is also experienced at the affective level: the sense of shame and guilt is widespread.

  17. Long-standing chin-augmenting costochondral graft creating a diagnostic challenge: A case report and literature review

    PubMed Central

    Mintline, Mark; Ruprecht, Axel; Cohen, Donald; Blumberg, Barton R.; Nair, Madhu K.

    2016-01-01

    To our knowledge, the imaging features of costochondral grafts (CCGs) on cone-beam computed tomography (CBCT) have not been documented in the literature. We present the case of a CCG in the facial soft tissue to the anterior mandible, with changes mimicking a cartilaginous neoplasm. This is the first report to describe the CBCT imaging features of a long-standing graft in the anterior mandible. Implants or grafts may be incidental findings on radiographic images made for unrelated purposes. Although most are well-defined and radiographically homogeneous, being of relatively inert non-biological material, immune reactions to some grafts may stimulate alterations in the appearance of surrounding tissues. Biological implants may undergo growth and differentiation, causing their appearance to mimic neoplastic lesions. We present the case of a cosmetic autogenous CCG that posed a diagnostic challenge both radiographically and histopathologically. PMID:28035307

  18. Mini-temporalis transposition: a less invasive procedure of smile restoration for long-standing incomplete facial paralysis.

    PubMed

    Chen, Gang; Yang, Xianxian; Wang, Wei; Li, Qingfeng

    2015-03-01

    Facial paralysis is a common craniofacial deformity that is responsible for significant psychological and functional impairment. Free muscle transfer in 2 stages and latissimus dorsi transfer in one stage may be the most effective surgical procedure for achieving a symmetrical spontaneous smile for a patient with complete facial paralysis. However, these 2 procedures are unsuitable for many incomplete patients. The authors introduce a less invasive procedure, termed mini-temporalis transposition that is able to achieve a symmetrical spontaneous smile in incomplete patients. Through a zigzag incision into the temporal region, the middle third of the temporalis is transferred and elongated with the palmaris longus tendon or combined with the deep temporal fascia. The strips are anchored to key points at the modiolus and the middle of the ipsilateral orbicularis oris muscle through a small intraoral incision and subcutaneous tunnel. The key points are marked during preoperative smile analysis. This procedure was applied to 15 patients with long-standing incomplete facial paralysis. All patients obtained improvements in smile symmetry after the operation, and patients' satisfaction was high. In addition, no damage to residual facial nerve functions or development of procedure-induced complications (such as a facial contour defect, lip eversion or puckering, or skin tethering) was observed in any of the patients. Nevertheless, slight temporal hollowing was observed in 4 patients, and mild bulkiness over the zygomatic arch was a common observation. In summary, the mini-temporalis transfer technique is a safe and effective method of smile restoration for long-standing incomplete facial paralysis.

  19. Addressing healthcare.

    PubMed

    Daly, Rich

    2013-02-11

    Though President Barack Obama has rarely made healthcare references in his State of the Union addresses, health policy experts are hoping he changes that strategy this year. "The question is: Will he say anything? You would hope that he would, given that that was the major issue he started his presidency with," says Dr. James Weinstein, left, of the Dartmouth-Hitchcock health system.

  20. Coronary vasospastic crisis leading to cardiogenic shock and recurrent ventricular fibrillation in a patient with long-standing asthma.

    PubMed

    Tacoy, Gulten; Kocaman, Sinan Altan; Balcioğlu, Serhat; Tanindi, Asli; Ozdemir, Murat; Cemri, Mustafa; Cengel, Atiye

    2008-12-01

    Acute myocardial infarction in patients with normal coronary arteries is a therapeutic dilemma. Coronary artery vasospasm and thrombosis are the most commonly encountered clinic problems and appear in localized coronary segments. The incidence of cardiovascular disease is increased in asthmatic patients. ß(2)-Adrenergic agonists use is associated with increased cardiovascular events. Although myocardial ischemia during asthma has been described in literature, acute myocardial infarction and ventricular fibrillation with normal coronary arteries in patients with asthma bronchiale is a rare entity. Our patient with long-standing asthma bronchiale presented with cardiogenic shock whose coronary angiography revealed multivessel disease and undergone primary percutaneous coronary intervention. Due to ongoing chest pain and hemodynamic instability; an early bypass surgery was planned. A control angiogram was performed before surgery. After intracoronary nitrate administration all narrowings in coronary vasculature disappeared. Symptom relief and clinical improvement was achieved with nitrate and calcium channel blockers later. After 2 months she was readmitted with cardiac arrest due to recurrent ventricular fibrillation and intracardiac defibrillator implantation was performed.

  1. An Old Road Rapidly Aging? The Settlement of Apollo's Long-Standing False Claims Act Lawsuit and the Changing Appeal of Commission-Based Recruitment

    ERIC Educational Resources Information Center

    Observatory on Borderless Higher Education, 2010

    2010-01-01

    Last month, higher education company the Apollo Group, Inc. (Apollo) confirmed that it entered into an agreement with the United States (US) federal government to resolve a long-standing lawsuit concerning its subsidiary, the for-profit University of Phoenix (Phoenix). Originating in 2003, the False Claims Act lawsuit filed by university officials…

  2. Why “What Data Are Necessary for This Project?” and Other Basic Questions are Important to Address in Public Health Informatics Practice and Research

    PubMed Central

    Dixon, Brian E.; Grannis, Shaun J.

    2011-01-01

    Despite the likelihood of poor quality data flowing from clinical information systems to public health information systems, current policies and practices are pushing for the adoption and use of even greater numbers of electronic data feeds. However, using poor data can lead to poor decision-making outcomes in public health. Therefore public health informatics professionals need to assess, and periodically re-evaluate, the quality of electronic data and their sources. Unfortunately there is currently a paucity of tools and strategies in use across public health agencies. Our Center of Excellence in Public Health Informatics is working to develop and disseminate tools and strategies for supporting on-going assessment of data quality and solutions for overcoming data quality challenges. In this article, we outline the need for better data quality assessment and our approach to the development of new tools and strategies. In other words, public health informatics professionals need to ask questions about the electronic data received by public health agencies, and we hope to create tools and strategies to help informaticians ask questions that will lead to improved population health outcomes. PMID:23569618

  3. Why "What Data Are Necessary for This Project?" and Other Basic Questions are Important to Address in Public Health Informatics Practice and Research.

    PubMed

    Dixon, Brian E; Grannis, Shaun J

    2011-01-01

    Despite the likelihood of poor quality data flowing from clinical information systems to public health information systems, current policies and practices are pushing for the adoption and use of even greater numbers of electronic data feeds. However, using poor data can lead to poor decision-making outcomes in public health. Therefore public health informatics professionals need to assess, and periodically re-evaluate, the quality of electronic data and their sources. Unfortunately there is currently a paucity of tools and strategies in use across public health agencies. Our Center of Excellence in Public Health Informatics is working to develop and disseminate tools and strategies for supporting on-going assessment of data quality and solutions for overcoming data quality challenges. In this article, we outline the need for better data quality assessment and our approach to the development of new tools and strategies. In other words, public health informatics professionals need to ask questions about the electronic data received by public health agencies, and we hope to create tools and strategies to help informaticians ask questions that will lead to improved population health outcomes.

  4. Questioning the Questions

    ERIC Educational Resources Information Center

    Tienken, Christopher H.; Goldberg, Stephanie; DiRocco, Dominic

    2010-01-01

    Historical accounts of questioning used in the education process trace back to Socrates. One of the best examples of his use of questioning is found in Plato's "The Republic." Socrates used a series of strategic questions to help his student Glaucon come to understand the concept of justice. Socrates purposefully posed a series of…

  5. Questioning the Questions

    ERIC Educational Resources Information Center

    Tienken, Christopher H.; Goldberg, Stephanie; DiRocco, Dominic

    2009-01-01

    Well-known historical accounts of questioning used in the education process trace back to Socrates. One of the best examples of his use of questioning is found in Plato's classic work "The Republic" (2003). Today, teachers still use questions as one way to help students develop productive thinking skills and to understand concepts and topics.…

  6. “A question of balance”: addressing the public health impacts of multinational enterprises in the OECD Guidelines for Multinational Enterprises

    PubMed Central

    Yang, Joshua S.; McDaniel, Patricia A.; Malone, Ruth E.

    2012-01-01

    Background The global community is beginning to address non-communicable diseases, but how to increase the accountability of multinational enterprises (MNEs) for the health impacts of their products and practices remains unclear. We examine the Organization for Economic Cooperation and Development’s (OECD) efforts to do so through voluntary MNE guidelines. Methods We developed a historical case study of how the OECD Guidelines for Multinational Enterprises were developed and revised from 1973–2000 through an analysis of publicly available archived OECD and tobacco industry documents. Results The first edition of the Guidelines was a purely economic instrument. Outside pressures and a desire to ward off more stringent regulatory efforts resulted in the addition over time of guidelines related to the environment, consumer interests, sustainable development, and human rights. Conclusion Despite their voluntary nature, the Guidelines can play a role in efforts to help balance the interests of MNEs and public health by providing a starting point for efforts to create binding provisions addressing MNEs’ contributions to disease burden or disease reduction. PMID:23046298

  7. Loss of Breathing Modulation of Heart Rate Variability in Patients with Recent and Long Standing Diabetes Mellitus Type II

    PubMed Central

    Estañol, Bruno; Fossion, Ruben; Toledo-Roy, Juan C.; Callejas-Rojas, José A.; Gien-López, José A.; Delgado-García, Guillermo R.; Frank, Alejandro

    2016-01-01

    Healthy subjects under rhythmic breathing have heart interbeat intervals with a respiratory band in the frequency domain that can be an index of vagal activity. Diabetes Mellitus Type II (DM) affects the autonomic nervous system of patients, thus it can be expected changes on the vagal activity. Here, the influence of DM on the breathing modulation of the heart rate is evaluated by analyzing in the frequency domain heart interbeat interval (IBI) records obtained from 30 recently diagnosed, 15 long standing DM patients, and 30 control subjects during standardized clinical tests of controlled breathing at 0.1 Hz, supine rest and standing upright. Fourier spectral analysis of IBI records quantifies heart rate variability in different regions: low-frequencies (LF, 0.04–0.15 Hz), high-frequencies (HF, 0.15–0.4 Hz), and a controlled breathing peak (RP, centered around 0.1 Hz). Two new parameters are introduced: the frequency radius rf (square root of the sum of LF and HF squared) and β (power of RP divided by the sum of LF and HF). As diabetes evolves, the controlled breathing peak loses power and shifts to smaller frequencies, indicating that heart rate modulation is slower in diabetic patients than in controls. In contrast to the traditional parameters LF, HF and LF/HF, which do not show significant differences between the three populations in neither of the clinical tests, the new parameters rf and β, distinguish between control and diabetic subjects in the case of controlled breathing. Sympathetic activity that is driven by the baroreceptor reflex associated with the 0.1 Hz breathing modulations is affected in DM patients. Diabetes produces not only a rigid heartbeat with less autonomic induced variability (rf diminishes), but also alters the coupling between breathing and heart rate (reduced β), due to a progressive decline of vagal and sympathetic activity. PMID:27802329

  8. Loss of Breathing Modulation of Heart Rate Variability in Patients with Recent and Long Standing Diabetes Mellitus Type II.

    PubMed

    Rivera, Ana Leonor; Estañol, Bruno; Fossion, Ruben; Toledo-Roy, Juan C; Callejas-Rojas, José A; Gien-López, José A; Delgado-García, Guillermo R; Frank, Alejandro

    2016-01-01

    Healthy subjects under rhythmic breathing have heart interbeat intervals with a respiratory band in the frequency domain that can be an index of vagal activity. Diabetes Mellitus Type II (DM) affects the autonomic nervous system of patients, thus it can be expected changes on the vagal activity. Here, the influence of DM on the breathing modulation of the heart rate is evaluated by analyzing in the frequency domain heart interbeat interval (IBI) records obtained from 30 recently diagnosed, 15 long standing DM patients, and 30 control subjects during standardized clinical tests of controlled breathing at 0.1 Hz, supine rest and standing upright. Fourier spectral analysis of IBI records quantifies heart rate variability in different regions: low-frequencies (LF, 0.04-0.15 Hz), high-frequencies (HF, 0.15-0.4 Hz), and a controlled breathing peak (RP, centered around 0.1 Hz). Two new parameters are introduced: the frequency radius rf (square root of the sum of LF and HF squared) and β (power of RP divided by the sum of LF and HF). As diabetes evolves, the controlled breathing peak loses power and shifts to smaller frequencies, indicating that heart rate modulation is slower in diabetic patients than in controls. In contrast to the traditional parameters LF, HF and LF/HF, which do not show significant differences between the three populations in neither of the clinical tests, the new parameters rf and β, distinguish between control and diabetic subjects in the case of controlled breathing. Sympathetic activity that is driven by the baroreceptor reflex associated with the 0.1 Hz breathing modulations is affected in DM patients. Diabetes produces not only a rigid heartbeat with less autonomic induced variability (rf diminishes), but also alters the coupling between breathing and heart rate (reduced β), due to a progressive decline of vagal and sympathetic activity.

  9. Educational differences in disability-free life expectancy: a comparative study of long-standing activity limitation in eight European countries.

    PubMed

    Mäki, Netta; Martikainen, Pekka; Eikemo, Terje; Menvielle, Gwenn; Lundberg, Olle; Ostergren, Olof; Jasilionis, Domantas; Mackenbach, Johan P

    2013-10-01

    Healthy life expectancy is a composite measure of length and quality of life and an important indicator of health in aging populations. There are few cross-country comparisons of socioeconomic differences in healthy life expectancy. Most of the existing comparisons focus on Western Europe and the United States, often relying on older data. To address these deficiencies, we estimated educational differences in disability-free life expectancy for eight countries from all parts of Europe in the early 2000s. Long-standing severe disability was measured as a Global Activity Limitation Indicator (GALI) derived from the European Union Statistics on Income and Living Conditions (EU-SILC) survey. Census-linked mortality data were collected by a recent project comparing health inequalities between European countries (the EURO-GBD-SE project). We calculated sex-specific educational differences in disability-free life expectancy between the ages of 30 and 79 years using the Sullivan method. The lowest disability-free life expectancy was found among Lithuanian men and women (33.1 and 39.1 years, respectively) and the highest among Italian men and women (42.8 and 44.4 years, respectively). Life expectancy and disability-free life expectancy were directly related to the level of education, but the educational differences were much greater in the latter in all countries. The difference in the disability-free life expectancy between those with a primary or lower secondary education and those with a tertiary education was over 10 years for males in Lithuania and approximately 7 years for males in Austria, Finland and France, as well as for females in Lithuania. The difference was smallest in Italy (4 and 2 years among men and women, respectively). Highly educated Europeans can expect to live longer and spend more years in better health than those with lower education. The size of the educational difference in disability-free life expectancy varies significantly between countries

  10. Increased sensitivity to thyroid hormone replacement therapy followed by hyponatremia and eosinophilia in a patient with long-standing young-onset primary hypothyroidism.

    PubMed

    Fujikawa, M; Okamura, K; Sato, K; Mizokami, T; Shiratsuchi, M; Fujishima, M

    1999-06-01

    We describe a 51-year-old woman with long-standing young-onset primary hypothyroidism. Serum cortisol, adrenocorticotropin, and arginine vasopressin levels were normal, but urinary excretion of 17-hydroxycorticosteroid was decreased. Administration of a very small initial dose of thyroid hormone induced severe acute complications including fever, palpitation, and sweating associated with a rapid decrease in serum thyrotropin level, a dramatic increase in serum alkaline-phosphatase level, and a decrease in serum total cholesterol level. A week later, the late complications of nausea, severe hyponatremia, and eosinophilia occurred. Serum cortisol level decreased slightly but remained within normal limits during this hyponatremic period. This rare case suggests that increased sensitivity to thyroid hormone can occur in long-standing primary hypothyroidism with biphasic clinical course of acute thyrotoxic complications followed by severe hyponatremia resembling hypoadrenocorticism.

  11. Delayed recovery of right ventricular systolic function after repair of long-standing tricuspid regurgitation associated with severe right ventricular failure.

    PubMed

    Kim, Jong Hun; Kim, Kyung Hwa; Choi, Jong Bum; Kuh, Ja Hong

    2016-03-01

    After tricuspid valve surgery for long-standing tricuspid regurgitation associated with right ventricular failure, reverse remodelling of the enlarged right ventricle, including recovery of right ventricular systolic function, is unpredictable. We present the case of a 31-year old man with early reduction of dilated right ventricular dimensions and delayed recovery of impaired right ventricular systolic function after valve repair for traumatic tricuspid regurgitation lasting 16 years.

  12. Diffuse aneurysmal degeneration of the brachial artery after long-standing high-flow arteriovenous fistula closure for hemodialysis at elbow level.

    PubMed

    De Santis, Francesco; Martini, Guido; Mani, Gabriele; Bernhard, Othmar

    2014-07-01

    While the possibility of development of a panarterial dilatation proximal to a long-standing high-flow posttraumatic arteriovenous fistula is well known, to the best of our knowledge, this event has never been described after vascular access for hemodialysis closure. We describe a man in whom a diffuse aneurysmal degeneration of the brachial artery has been highlighted 6 months after long-standing high-flow arteriovenous fistula closure. A 47-year-old man developed a painful pulsatile mass in the anterior distal third of his arm 6 months after long-standing high-flow arteriovenous fistula closure at the level of his elbow. A computed tomography scan revealed multiple "true" aneurysms of the brachial artery (BA) that appeared enlarged in toto. One of these aneurysms (near the BA bifurcation) presented with significant thrombus stratification. Surgery was recommended because of the major risk of peripheral embolization. Considering the anatomic characteristics of both the BA and aneurysm, no arterial substitution was performed and, after removal of the thrombus, the aneurysm diameter was reduced via direct arterial wall suture. The patient was discharged under oral anticoagulation. Aneurysmal degeneration of the donor artery after vascular access is relatively rare but represents a challenging problem. Operative or conservative management of these aneurysms should evaluate both the possible aneurysm-related complications and the feasibility of vascular reconstruction. In this context, the risk of additional donor artery and/or vascular reconstruction enlargement over time should also be considered.

  13. Pesticide Labeling Questions & Answers

    EPA Pesticide Factsheets

    Pesticide manufacturers, applicators, state regulatory agencies, and other stakeholders raise questions or issues about pesticide labels. The questions on this page are those that apply to multiple products or address inconsistencies among product labels.

  14. Innovate-Ideagora: Addressing Core Questions

    ERIC Educational Resources Information Center

    Easton, Denise; McCord, Alan

    2009-01-01

    In this edition of Innovate-Ideagora, Denise Easton and Alan McCord announce the consolidation of Innovate-Live, "Innovate's" venue for author webcasts, with Ideagora; webcasts will now be accessed from Ideagora, and archives will be made available through Ideagora. This change will simplify presentation and merge our multimedia presentations,…

  15. Law addresses question of space artifact ownership

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-10-01

    U.S. astronauts who participated in many of NASA's early space missions will receive full ownership rights to artifacts from those missions through legislation that President Barack Obama signed into law on 25 September. The legislation, which received broad bipartisan support, provides artifact ownership rights to any of NASA's Mercury, Gemini, or Apollo space programs through the completion of the Apollo-Soyuz Test Project, whose flight occurred in July 1975. The law defines artifacts as expendable, disposable, or personal use items—including personal logs and flight hardware salvaged from jettisoned lunar modules—used by astronauts that were not required to be returned to NASA; lunar rocks and other lunar material are not defined as artifacts. Bill cosponsor Rep. Ralph Hall (R-Tex.), chair of the House of Representatives' Committee on Science, Space, and Technology, said on 19 September, “A majority of these items have been in the personal possession of the astronauts for 40 years or more. Over the last decade, NASA has begun to challenge the astronauts' ownership of these mementos. This issue was first brought to my attention late last year. I was surprised to learn that NASA had, on an irregular basis, intervened several times to claim ownership.”

  16. A Question of Questions.

    ERIC Educational Resources Information Center

    Fenwick, John; McMillan, Rod

    In a conventional teaching situation, a lecturer may use a wide range of questioning techniques aimed at helping students to become active learners. In distance learning, students are often isolated and have limited opportunities for interaction in a social learning environment. Hence, learning strategies in distance learning need to be structured…

  17. Squamous cell carcinoma of the cecum developing in a patient with long-standing ulcerative colitis and a coexistent carcinoid tumor in the appendix: A case report.

    PubMed

    Ahmad, Saqib; Watson, Nicholas; Shamim, Kiran; Menon, Achyuth; Abdullah, Khorrum

    2015-09-01

    Squamous cell carcinoma (SCC) of the colon is a rare tumor that accounts for 0.1%-0.2% of colonic malignancies. However, pure SCC of the cecum is extremely rare. Although SCC of the colon is a rare complication of idiopathic inflammatory bowel disease (IBD), SCC of the cecum in the context of IBD has not been previously reported in the English literature. We report a case of the coexistence of SCC of the cecum and a carcinoid tumor in a 46-year-old female with long-standing pan-ulcerative colitis.

  18. Multiple Meningioma in a Patient of Bipolar Disorder: The Dilemma of Detecting Structural Brain Lesions in the Backdrop of a Long Standing Psychiatric Illness

    PubMed Central

    Sood, Mamta; Khandelwal, Sudhir Kumar

    2016-01-01

    Multiple meningioma often can be clinically silent and may present with only psychiatric symptoms. We report a case of 43-year-old, right handed woman with a 23 year history of long standing bipolar affective disorder, who presented with a mixed episode with psychotic symptoms which did not respond to usual treatment and was further complicated with a different set of symptomatology. MRI brain revealed multiple dural based mass lesions identified to be multiple meningiomas. Patient’s symptoms improved after gamma knife stereotactic radiosurgery for the multiple meningioma. Our finding illustrates the need to assess for brain lesions in presence of atypical symptoms, along with unresponsiveness to traditional management with psychotropic medications in patients with bipolar affective disorders. PMID:27656537

  19. Case report of primary renal pelvis squamous cell carcinoma coexisting with long-standing calculi in left kidney on 18F-FDG PET/CT

    PubMed Central

    Deng, Shengming; Zhang, Bin; Huang, Ying; Li, Jihui; Sang, Shibiao; Zhang, Wei

    2017-01-01

    Abstract Rationale: Primary renal pelvis squamous cell carcinoma (SCC) is an extremely rare neoplasm. In many patients, the SCC was associated with renal calculi. Patient concerns: A 61-year-old male presented with intermittent pain at the left lumbar region for 3 days. The PET/CT images demonstrated increased 18F-FDG uptake in the upper pole of the left kidney and left renal hilar lymph nodes. Diagnoses: Pathologic examination revealed well-moderately differentiated renal pelvis SCC with lymphatic metastasis. Interventions: The patient underwent a left nephrectomy a few days after the initial staging PET/CT study. Outcomes: No growing lesion or metastasis was observed during a 6-month follow-up. Lessons: Our case demonstrates that 18F-FDG PET/CT is a useful diagnostic tool to evaluate primary renal pelvic SCC and detect metastatic lymph nodes in patients with long-standing calculi. PMID:28296764

  20. Anti-TNF therapy in the management of ocular attacks in an elderly patient with long-standing Behçet’s disease

    PubMed Central

    Karube, Hisako; Kamoi, Koju; Ohno-Matsui, Kyoko

    2016-01-01

    Background Ocular symptoms in Behçet’s disease (BD) begin mostly before 30 years of age according to international surveys, and BD activity may decrease with age. Information regarding the treatment of ocular symptoms in elderly BD patients is thus scant. Anti-TNFα antibody has recently demonstrated strong effects against recurrent uveitis in BD, but the efficacy and safety of anti-TNFα therapy in elderly patients remain unclear. We report herein the case of an elderly patient with long-standing uveitis due to BD who was successfully treated with two types of anti-TNF therapy. Case An 81-year-old Japanese man presented with a 33-year history of ocular inflammation due to BD. As immunosuppressive agents, such as cyclosporine A, were difficult to use because he had undergone removal of the left kidney due to cancer, he was treated with colchicine. However, attacks of ocular inflammation persisted around nine times a year. After colchicine had been changed to infliximab, ocular inflammation was fairly well controlled, but ocular attacks still occurred once or twice a year. As soon as intestinal hemorrhage related to BD occurred, infliximab was switched to adalimumab. After this switch, ocular attacks resolved and visual acuity was maintained at 1.0. Intestinal lesions were also well controlled, and no side effects were seen. Conclusion This represents the first report of the application of two types of anti-TNFα therapy for ocular attacks in an elderly BD patient. In addition to infliximab, adalimumab appears to offer an alternative therapy for refractory, long-standing BD-related uveitis in elderly patients. PMID:27729816

  1. A case and a series of published cases of esthesioneuroblastoma (ENB) in which long-standing paraneoplastic SIADH had preceded ENB diagnosis.

    PubMed

    Gabbay, Uri; Leider-Trejo, Leonor; Marshak, Gideon; Gabbay, Merav; Fliss, Dan M

    2013-01-01

    Esthesioneuroblastoma (ENB) is a rare tumor of the olfactory mucosa. We treated a 50-year-old man with an ENB in the right ethmoid sinus who had been diagnosed 16 years earlier with syndrome of inappropriate antidiuretic hormone secretion (SIADH) of unknown cause. When the ENB was surgically removed, the patient's osmoregulation returned to normal-that is, his SIADH resolved completely, which suggested that the SIADH was paraneoplastic in nature. These events prompted us to review the literature to determine if there is an association between our patient's ENB and his SIADH in general and between long-standing SIADH that precedes ENB in particular. Based on our review and an extrapolation of data, we have estimated that 1,300 cases of ENB have occurred since it was first described in 1924. Of these cases, SIADH was reported in 26 cases, including ours, which represents an estimated prevalence of 2% (although we believe this is actually an underestimation of the true prevalence). Of the 26 cases, SIADH had already been present in 14 patients (54%) prior to their diagnosis of EBN for a median duration of 3.5 years. We recommend that patients with newly diagnosed EBN be evaluated for SIADH. In those who are SIADH-positive, a resolution of SIADH should be expected once the ENB has been removed. If this does not occur, one should suspect that the ENB was not completely removed. If SIADH resolves but later recurs during follow-up, then a relapse should be suspected. In long-standing SIADH of unknown etiology, nasal sinus imaging should be considered.

  2. Inaugural address

    NASA Astrophysics Data System (ADS)

    Joshi, P. S.

    2014-03-01

    From jets to cosmos to cosmic censorship P S Joshi Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India E-mail: psj@tifr.res.in 1. Introduction At the outset, I should like to acknowledge that part of the title above, which tries to capture the main flavour of this meeting, and has been borrowed from one of the plenary talks at the conference. When we set out to make the programme for the conference, we thought of beginning with observations on the Universe, but then we certainly wanted to go further and address deeper questions, which were at the very foundations of our inquiry, and understanding on the nature and structure of the Universe. I believe, we succeeded to a good extent, and it is all here for you in the form of these Conference Proceedings, which have been aptly titled as 'Vishwa Mimansa', which could be possibly translated as 'Analysis of the Universe'! It is my great pleasure and privilege to welcome you all to the ICGC-2011 meeting at Goa. The International Conference on Gravitation and Cosmology (ICGC) series of meetings are being organized by the Indian Association for General Relativity and Gravitation (IAGRG), and the first such meeting was planned and conducted in Goa in 1987, with subsequent meetings taking place at a duration of about four years at various locations in India. So, it was thought appropriate to return to Goa to celebrate the 25 years of the ICGC meetings. The recollections from that first meeting have been recorded elsewhere here in these Proceedings. The research and teaching on gravitation and cosmology was initiated quite early in India, by V V Narlikar at the Banares Hindu University, and by N R Sen in Kolkata in the 1930s. In course of time, this activity grew and gained momentum, and in early 1969, at the felicitation held for the 60 years of V V Narlikar at a conference in Ahmedabad, P C Vaidya proposed the formation of the IAGRG society, with V V Narlikar being the first President. This

  3. Questions for Music Education Research

    ERIC Educational Resources Information Center

    Jorgensen, Estelle R.

    2008-01-01

    In addressing the question-set "What questions do music education researchers need to address?", an illustrative list of juxtaposed descriptive and normative questions is sketched as follows: What are and should be the dimensions of music education? What are and should be the institutional agencies of music education? What are and should be the…

  4. Approaches to Cell Biology Teaching: Questions about Questions

    ERIC Educational Resources Information Center

    Allen, Deborah; Tanner, Kimberly

    2002-01-01

    There are many questions to be asked about the pedagogical practice of questioning. Questions provide insight into what students at any age or grade level already know about a topic, which provides a beginning point for teaching. Questions reveal misconceptions and misunderstandings that must be addressed for teachers to move student thinking…

  5. Commentary: Recommendations and remaining questions for health care leadership training programs.

    PubMed

    Stoller, James K

    2013-01-01

    Effective leadership is critical for optimizing cost, access, and quality in health care. Creating a pipeline of effective health care leaders requires developing leadership competencies that differ from the usual criteria of clinical and scientific excellence by which physicians have traditionally been promoted to leadership positions. Specific competencies that differentiate effective leaders from average leaders, especially emotional intelligence and its component abilities, are essential for effective leadership.Adopting a long-standing practice from successful corporations, some health care institutions, medical societies, and business schools now offer leadership programs that address these differentiating leadership competencies. The author draws on experience with such programs through the Cleveland Clinic Academy to provide recommendations for health care leadership training and to identify unanswered questions about such programs.The author recommends that such training should be broadly available to all health care leadership communities (i.e., nurses, administrators, and physicians). A progressive curriculum, starting with foundational concepts and extending to coaching and feedback opportunities through experiential learning, recognizes the challenge of becoming an effective leader and the long time line needed to do so. Linking leadership courses to continuing medical education and to graduate credit opportunities is appealing to participants. Other recommendations focus on the importance of current leaders' involvement in nominating emerging leaders for participation, embedding leadership development discussions in faculty's professional reviews, and blending discussion of frameworks and theory with practical, experiential lessons. The author identifies questions about the benefits of formal health care leadership training that remain to be answered.

  6. Highly Stereoselective Synthesis of Anti, Anti-Dipropionate Stereotriads: A Solution to the Long-Standing Problem of Challenging Mismatched Double Asymmetric Crotylboration Reactions#

    PubMed Central

    Chen, Ming; Roush, William R.

    2012-01-01

    The stereocontrolled synthesis of the β-branched anti, anti-dipropionate stereotriad 4 via aldol or crotylmetal chemistry represents a historical challenge to the organic synthesis community. Here we describe a general solution to the long-standing problem associated with the synthesis of 4 by utilizing mismatched double asymmetric crotylboration reactions of enantioenriched α-methyl substituted aldehydes with the chiral, nonracemic crotylborane reagent (S)-(E)-22 (or its enantiomer). This method not only provides direct access to anti, anti-dipropionate stereotriads 24 [a synthetic equivalent of 4] with very good (5-8:1) if not excellent (≥15:1) diastereoselectivity from β-branched chiral aldehydes with ≤50:1 intrinsic diastereofacial selectivity preferences, but also provides a vinylstannane unit in the products that is properly functionalized for use in subsequent C-C bond forming events. We anticipate that this method will be widely applicable and will lead to substantial simplification of strategies for synthesis of polyketide natural products. PMID:22332989

  7. Heart Rate and Systolic Blood Pressure Variability in the Time Domain in Patients with Recent and Long-Standing Diabetes Mellitus.

    PubMed

    Rivera, Ana Leonor; Estañol, Bruno; Sentíes-Madrid, Horacio; Fossion, Ruben; Toledo-Roy, Juan C; Mendoza-Temis, Joel; Morales, Irving O; Landa, Emmanuel; Robles-Cabrera, Adriana; Moreno, Rene; Frank, Alejandro

    2016-01-01

    Diabetes Mellitus (DM) affects the cardiovascular response of patients. To study this effect, interbeat intervals (IBI) and beat-to-beat systolic blood pressure (SBP) variability of patients during supine, standing and controlled breathing tests were analyzed in the time domain. Simultaneous noninvasive measurements of IBI and SBP for 30 recently diagnosed and 15 long-standing DM patients were compared with the results for 30 rigorously screened healthy subjects (control). A statistically significant distinction between control and diabetic subjects was provided by the standard deviation and the higher moments of the distributions (skewness, and kurtosis) with respect to the median. To compare IBI and SBP for different populations, we define a parameter, α, that combines the variability of the heart rate and the blood pressure, as the ratio of the radius of the moments for IBI and the same radius for SBP. As diabetes evolves, α decreases, standard deviation of the IBI detrended signal diminishes (heart rate signal becomes more "rigid"), skewness with respect to the median approaches zero (signal fluctuations gain symmetry), and kurtosis increases (fluctuations concentrate around the median). Diabetes produces not only a rigid heart rate, but also increases symmetry and has leptokurtic distributions. SBP time series exhibit the most variable behavior for recently diagnosed DM with platykurtic distributions. Under controlled breathing, SBP has symmetric distributions for DM patients, while control subjects have non-zero skewness. This may be due to a progressive decrease of parasympathetic and sympathetic activity to the heart and blood vessels as diabetes evolves.

  8. Question Mapping

    ERIC Educational Resources Information Center

    Martin, Josh

    2012-01-01

    After accepting the principal position at Farmersville (TX) Junior High, the author decided to increase instructional rigor through question mapping because of the success he saw using this instructional practice at his prior campus. Teachers are the number one influence on student achievement (Marzano, 2003), so question mapping provides a…

  9. Curiosity Questions

    ERIC Educational Resources Information Center

    Nelsen, Jane; DeLorenzo, Chip

    2010-01-01

    Have you ever found yourself lecturing a child, with the best of intentions, in an attempt to help him or her learn a lesson or process a situation in a manner that you feel will be productive? Curiosity questions, which the authors also call What and How questions, help children process an experience, event, or natural consequence so that they…

  10. Use of Oral Cholera Vaccine and Knowledge, Attitudes, and Practices Regarding Safe Water, Sanitation and Hygiene in a Long-Standing Refugee Camp, Thailand, 2012-2014

    PubMed Central

    Phares, Christina R.; Wannemuehler, Kathleen A.; Nyangoma, Edith; Taylor, Eboni M.; Fulton, Anna; Wongjindanon, Nuttapong; Aung, Naw Rody; Travers, Phillipe; Date, Kashmira

    2016-01-01

    Oral cholera vaccines (OCVs) are relatively new public health interventions, and limited data exist on the potential impact of OCV use on traditional cholera prevention and control measures—safe water, sanitation and hygiene (WaSH). To assess OCV acceptability and knowledge, attitudes, and practices (KAPs) regarding cholera and WaSH, we conducted cross-sectional surveys, 1 month before (baseline) and 3 and 12 months after (first and second follow-up) a preemptive OCV campaign in Maela, a long-standing refugee camp on the Thailand-Burma border. We randomly selected households for the surveys, and administered questionnaires to female heads of households. In total, 271 (77%), 187 (81%), and 199 (85%) households were included in the baseline, first and second follow-up surveys, respectively. Anticipated OCV acceptability was 97% at baseline, and 91% and 85% of household members were reported to have received 1 and 2 OCV doses at first follow-up. Compared with baseline, statistically significant differences (95% Wald confidence interval not overlapping zero) were noted at first and second follow-up among the proportions of respondents who correctly identified two or more means of cholera prevention (62% versus 78% and 80%), reported boiling or treating drinking water (19% versus 44% and 69%), and washing hands with soap (66% versus 77% and 85%); a significant difference was also observed in the proportion of households with soap available at handwashing areas (84% versus 90% and 95%), consistent with reported behaviors. No significant difference was noted in the proportion of households testing positive for Escherichia coli in stored household drinking water at second follow-up (39% versus 49% and 34%). Overall, we observed some positive, and no negative changes in cholera- and WaSH-related KAPs after an OCV campaign in Maela refugee camp. OCV campaigns may provide opportunities to reinforce beneficial WaSH-related KAPs for comprehensive cholera prevention and

  11. Epithelial-to-mesenchymal transition in a fistula-associated anal adenocarcinoma in a patient with long-standing Crohn's disease.

    PubMed

    Scharl, Michael; Frei, Pascal; Frei, Sandra M; Biedermann, Luc; Weber, Achim; Rogler, Gerhard

    2014-01-01

    Anal adenocarcinomas arising from perianal fistulae represent a rare complication in Crohn's disease (CD) patients. We have previously demonstrated the involvement of an epithelial-to-mesenchymal transition (EMT) in the pathogenesis of CD-associated fistulae. Although EMT has also been implicated in the development of colorectal and anal carcinoma, the molecular link from fistula to carcinoma is unclear. We present a case of a 48-year-old White woman who developed a mucinous anal adenocarcinoma originating from a perianal, CD-associated fistula 24 years after being diagnosed with CD. To characterize the expression of EMT-associated molecules in fistula and carcinoma tissue, immunohistochemical analysis for Snail1, Slug, β-catenin and E-cadherin was performed. A mucinous anal adenocarcinoma developed on a perianal fistula in a patient with long-standing CD. After neoadjuvant radiochemotherapy, the fistula-associated tumour was resected and the patient is presently in remission. Using immunohistochemical analysis, we detected a remarkable staining of the Slug transcription factor in transitional cells lining the fistula tract. This observation is unique to this 'carcinoma'-fistula: we had previously shown Slug expression in cells surrounding the fistula tract but not in transitional cells. Expression of Snail1, β-catenin and E-cadherin in this case was comparable with our previous findings. We describe a rare case of a CD fistula-associated adenocarcinoma within an area of squamous epithelium of the perianal area and an unusual expression pattern of EMT markers in this fistula. This case seems to underline the relevance of our previous findings demonstrating that EMT plays an important role for fistula pathogenesis and likely carcinogenesis in CD patients.

  12. Use of Oral Cholera Vaccine and Knowledge, Attitudes, and Practices Regarding Safe Water, Sanitation and Hygiene in a Long-Standing Refugee Camp, Thailand, 2012-2014.

    PubMed

    Scobie, Heather M; Phares, Christina R; Wannemuehler, Kathleen A; Nyangoma, Edith; Taylor, Eboni M; Fulton, Anna; Wongjindanon, Nuttapong; Aung, Naw Rody; Travers, Phillipe; Date, Kashmira

    2016-12-01

    Oral cholera vaccines (OCVs) are relatively new public health interventions, and limited data exist on the potential impact of OCV use on traditional cholera prevention and control measures-safe water, sanitation and hygiene (WaSH). To assess OCV acceptability and knowledge, attitudes, and practices (KAPs) regarding cholera and WaSH, we conducted cross-sectional surveys, 1 month before (baseline) and 3 and 12 months after (first and second follow-up) a preemptive OCV campaign in Maela, a long-standing refugee camp on the Thailand-Burma border. We randomly selected households for the surveys, and administered questionnaires to female heads of households. In total, 271 (77%), 187 (81%), and 199 (85%) households were included in the baseline, first and second follow-up surveys, respectively. Anticipated OCV acceptability was 97% at baseline, and 91% and 85% of household members were reported to have received 1 and 2 OCV doses at first follow-up. Compared with baseline, statistically significant differences (95% Wald confidence interval not overlapping zero) were noted at first and second follow-up among the proportions of respondents who correctly identified two or more means of cholera prevention (62% versus 78% and 80%), reported boiling or treating drinking water (19% versus 44% and 69%), and washing hands with soap (66% versus 77% and 85%); a significant difference was also observed in the proportion of households with soap available at handwashing areas (84% versus 90% and 95%), consistent with reported behaviors. No significant difference was noted in the proportion of households testing positive for Escherichia coli in stored household drinking water at second follow-up (39% versus 49% and 34%). Overall, we observed some positive, and no negative changes in cholera- and WaSH-related KAPs after an OCV campaign in Maela refugee camp. OCV campaigns may provide opportunities to reinforce beneficial WaSH-related KAPs for comprehensive cholera prevention and control.

  13. Conditioning with Fludarabine-Busulfan versus Busulfan-Cyclophosphamide Is Associated with Lower aGVHD and Higher Survival but More Extensive and Long Standing Bone Marrow Damage

    PubMed Central

    Ye, YongBin; Wang, Jing; Huang, YuXian; Weng, GuangYang; Zhang, MingWan

    2016-01-01

    Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and a major cause of nonrelapse mortality after allo-HSCT. A conditioning regimen plays a pivotal role in the development of aGVHD. To provide a platform for studying aGVHD and evaluating the impact of different conditioning regimens, we established a murine aGVHD model that simulates the clinical situation and can be conditioned with Busulfan-Cyclophosphamide (Bu-Cy) and Fludarabine-Busulfan (Flu-Bu). In our study, BALB/c mice were conditioned with Bu-Cy or Flu-Bu and transplanted with 2 × 107 bone marrow cells and 2 × 107 splenocytes from either allogeneic (C57BL/6) or syngeneic (BALB/c) donors. The allogeneic recipients conditioned with Bu-Cy had shorter survivals (P < 0.05), more severe clinical manifestations, and higher hepatic and intestinal pathology scores, associated with increased INF-γ expression and diminished IL-4 expression in serum, compared to allogeneic recipients conditioned with Flu-Bu. Moreover, higher donor-derived T-cell infiltration and severely impaired B-cell development were seen in the bone marrow of mice, exhibiting aGVHD and conditioned with Flu-Bu. Our study showed that the conditioning regimen with Bu-Cy resulted in more severe aGVHD while the Flu-Bu regimen was associated with more extensive and long standing bone marrow damage. PMID:27843940

  14. Consistency of Quantitative Scores of Hypoglycemia Severity and Glycemic Lability and Comparison with Continuous Glucose Monitoring System Measures in Long-Standing Type 1 Diabetes

    PubMed Central

    Bellin, Melena D.; Alejandro, Rodolfo; Yankey, Jon W.; Clarke, William R.; Qidwai, Julie C.; Schwieger, Traci R.; Eggerman, Thomas L.; Robien, Mark A.

    2015-01-01

    Abstract Background: In long-standing type 1 diabetes (T1D), loss of endogenous insulin secretion and glucose dysregulation can lead to severe hypoglycemia and associated complications. Here, we report the serial consistency and the correlation between different scores that characterize glucose dysregulation using self-monitoring of blood glucose (SMBG), in a cohort of T1D individuals being evaluated for transplant eligibility in Clinical Islet Transplantation Consortium trials. Subjects and Methods: In total, 152 C-peptide–negative T1D subjects with at least one severe hypoglycemia episode in the prior year documented SMBG at enrollment and every 6 months until deemed ineligible or transplanted. SMBG was used to calculate the HYPO score, Lability Index (LI), and mean amplitude of glycemic excursion (MAGE). Additionally, a blinded continuous glucose monitoring system (CGMS) was worn for 72 h at enrollment and every 12 months. Results: In this cohort, LI was the most consistent (intraclass correlation coefficient=0.70) over time, followed by the HYPO score (0.51), with MAGE being the least consistent (0.36). Although MAGE and LI were highly correlated with each other, neither correlated with CGMS SD or glucose coefficient of variation (CV). Subjects spent a median of 97 min/day at <54 mg/dL using CGMS. The HYPO score correlated with CGMS time below 54 mg/dL and glucose CV. Conclusions: The HYPO score and LI are more consistent than MAGE in patients with established T1D experiencing severe hypoglycemic events and may be especially useful both for identifying subjects experiencing the greatest difficulty in maintaining glycemic control and for longitudinal assessment of novel interventions. PMID:25629445

  15. Gene expression profiles for the human pancreas and purified islets in Type 1 diabetes: new findings at clinical onset and in long-standing diabetes

    PubMed Central

    Planas, R; Carrillo, J; Sanchez, A; Ruiz de Villa, M C; Nuñez, F; Verdaguer, J; James, R F L; Pujol-Borrell, R; Vives-Pi, M

    2010-01-01

    Type 1 diabetes (T1D) is caused by the selective destruction of the insulin-producing β cells of the pancreas by an autoimmune response. Due to ethical and practical difficulties, the features of the destructive process are known from a small number of observations, and transcriptomic data are remarkably missing. Here we report whole genome transcript analysis validated by quantitative reverse transcription–polymerase chain reaction (qRT–PCR) and correlated with immunohistological observations for four T1D pancreases (collected 5 days, 9 months, 8 and 10 years after diagnosis) and for purified islets from two of them. Collectively, the expression profile of immune response and inflammatory genes confirmed the current views on the immunopathogenesis of diabetes and showed similarities with other autoimmune diseases; for example, an interferon signature was detected. The data also supported the concept that the autoimmune process is maintained and balanced partially by regeneration and regulatory pathway activation, e.g. non-classical class I human leucocyte antigen and leucocyte immunoglobulin-like receptor, subfamily B1 (LILRB1). Changes in gene expression in islets were confined mainly to endocrine and neural genes, some of which are T1D autoantigens. By contrast, these islets showed only a few overexpressed immune system genes, among which bioinformatic analysis pointed to chemokine (C-C motif) receptor 5 (CCR5) and chemokine (CXC motif) receptor 4) (CXCR4) chemokine pathway activation. Remarkably, the expression of genes of innate immunity, complement, chemokines, immunoglobulin and regeneration genes was maintained or even increased in the long-standing cases. Transcriptomic data favour the view that T1D is caused by a chronic inflammatory process with a strong participation of innate immunity that progresses in spite of the regulatory and regenerative mechanisms. PMID:19912253

  16. An incidental finding of a long-standing button battery in the floor of the nose during a routine orthodontic examination.

    PubMed

    Parker, Kate; Visram, Semina; Hodges, Samantha

    2016-06-01

    Foreign body insertion into the ears and nose is common in children and is often witnessed by the carer or reported by the child and therefore appropriate management can be sought promptly. However, these incidents can go unreported and may be accompanied by non-specific symptoms making diagnosis difficult. Button batteries are common in everyday life and their small size and shiny appearance make them appealing to children and their ingestion or insertion is not uncommon. Due to their size, shape and electrochemical composition button batteries pose serious complications if ingested, inhaled or inserted. In the nose they usually cause intense local tissue reactions resulting in severe tissue destruction, septal necrosis or stenosis of the nasal cavity as well as posing the risk of subsequently being ingested or aspirated. This case report details an incidental finding of a button battery in the floor of the nose discovered on routine orthodontic radiographs. An upper standard occlusal and dental panoramic tomography showed a radiopaque, cylindrical, object in the floor of the nose which a subsequent CBCT localized to the floor of the right nasal fossa. The patient required orthodontic extractions and the exposure and bonding of teeth under general anaesthetic. Therefore the battery was removed by the maxillofacial surgery team at the same general anaesthetic. This is a rare case of an incidental finding of a long-standing button battery impaction which was asymptomatic and did not have any detrimental effects. This case highlights the dangers of button battery impaction and the need for prompt referral for removal.

  17. Heart Rate and Systolic Blood Pressure Variability in the Time Domain in Patients with Recent and Long-Standing Diabetes Mellitus

    PubMed Central

    Rivera, Ana Leonor; Estañol, Bruno; Sentíes-Madrid, Horacio; Fossion, Ruben; Toledo-Roy, Juan C.; Mendoza-Temis, Joel; Morales, Irving O.; Landa, Emmanuel; Robles-Cabrera, Adriana; Moreno, Rene; Frank, Alejandro

    2016-01-01

    Diabetes Mellitus (DM) affects the cardiovascular response of patients. To study this effect, interbeat intervals (IBI) and beat-to-beat systolic blood pressure (SBP) variability of patients during supine, standing and controlled breathing tests were analyzed in the time domain. Simultaneous noninvasive measurements of IBI and SBP for 30 recently diagnosed and 15 long-standing DM patients were compared with the results for 30 rigorously screened healthy subjects (control). A statistically significant distinction between control and diabetic subjects was provided by the standard deviation and the higher moments of the distributions (skewness, and kurtosis) with respect to the median. To compare IBI and SBP for different populations, we define a parameter, α, that combines the variability of the heart rate and the blood pressure, as the ratio of the radius of the moments for IBI and the same radius for SBP. As diabetes evolves, α decreases, standard deviation of the IBI detrended signal diminishes (heart rate signal becomes more “rigid”), skewness with respect to the median approaches zero (signal fluctuations gain symmetry), and kurtosis increases (fluctuations concentrate around the median). Diabetes produces not only a rigid heart rate, but also increases symmetry and has leptokurtic distributions. SBP time series exhibit the most variable behavior for recently diagnosed DM with platykurtic distributions. Under controlled breathing, SBP has symmetric distributions for DM patients, while control subjects have non-zero skewness. This may be due to a progressive decrease of parasympathetic and sympathetic activity to the heart and blood vessels as diabetes evolves. PMID:26849653

  18. A question of choice.

    PubMed

    Grabiner, Gene

    2011-06-22

    Women's reproductive rights, reproductive health, and constitutional privacy rights in the United States are addressed in light of the contemporary onslaught of the Christian Right. The misuse of State power by fundamentalist social forces in America is critiqued. The article also briefly reviews the question of State control over women's bodies.

  19. A Question of Choice

    PubMed Central

    2011-01-01

    Women's reproductive rights, reproductive health, and constitutional privacy rights in the United States are addressed in light of the contemporary onslaught of the Christian Right. The misuse of State power by fundamentalist social forces in America is critiqued. The article also briefly reviews the question of State control over women's bodies. PMID:21696627

  20. Questionable Exercises.

    ERIC Educational Resources Information Center

    Liemohn, Wendell; Haydu, Traci; Phillips, Dawn

    1999-01-01

    This publication presents general guidelines for exercise prescription that have an anatomical basis but also consider the exerciser's ability to do the exercise correctly. It reviews various common questionable exercises, explaining how some exercises, especially those designed for flexibility and muscle fitness, can cause harm. Safer…

  1. Questor's Question

    ERIC Educational Resources Information Center

    Erickson, Mary; Dock, Michelle Nichols; Eldridge, Laurie

    2009-01-01

    Questor is a curious little bird whose four broad questions are helpful to anyone interested in making art or understanding the art of others. He was designed as a character in an online video for children, "Building on a River: Questor's Tale." The video is narrated by Questor, who relates the 2000 year history of architecture along the Salt…

  2. "The" Question.

    ERIC Educational Resources Information Center

    Lowe, Pardee, Jr.

    1984-01-01

    Examines the suggestions found in Michael Canale's paper, "Considerations in the Testing of Reading and Listening Proficiency," in the light of a possible U.S. Government's Interagency Language Roundtable receptive skills proficiency test which must supply the answer to the question of how well an individual can understand a particular…

  3. Critical Questions.

    ERIC Educational Resources Information Center

    Worthy, Jo; Hoffman, James V.

    1998-01-01

    Offers responses from four readers of this journal, all reading and/or classroom teachers, to a question posed by another teacher: whether children who have had limited literacy experiences should start reading in whole-language readers and/or trade books or whether they should start in controlled-vocabulary preprimers. (SR)

  4. Four Questions

    ERIC Educational Resources Information Center

    Hark-Weber, Amara G., Ed.

    2013-01-01

    Teaching artists often find themselves working in schools and communities that are new to them, whether these are situations close to home or farther afield. This issue of Four Questions highlights teaching artists who travel extensively as part of their teaching and artistic practices and bring their expertise, energy, and creativity to…

  5. Convocation address.

    PubMed

    Kakodkar, A

    1999-07-01

    This convocation addressed by Dr. Anil Kakodkar focuses on the challenges faced by graduating students. In his speech, he emphasized the high level of excellence achieved by the industrial sector; however, he noted that there has been a loss of initiative in maximizing value addition, which was worsened by an increasing population pressure. In facing a stiff competition in the external and domestic markets, it is imperative to maximize value addition within the country in a competitive manner and capture the highest possible market share. To achieve this, high-quality human resources are central. Likewise, family planning programs should become more effective and direct available resources toward national advantage. To boost the domestic market, he suggests the need to search for strengths to achieve leadership position in those areas. First, an insight into the relationship between the lifestyles and the needs of our people and the natural resource endowment must be gained. Second, remodeling of the education system must be undertaken to prepare the people for adding the necessary innovative content in our value addition activities. Lastly, Dr. Kakodkar emphasizes the significance of developing a strong bond between parents and children to provide a sound foundation and allow the education system to grow upon it.

  6. Opening Address

    NASA Astrophysics Data System (ADS)

    Yamada, T.

    2014-12-01

    Ladies and Gentlemen, it is my great honor and pleasure to present an opening address of the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3). On the behalf of the organizing committee, I certainly welcome all your visits to KGU Kannai Media Center belonging to Kanto Gakuin University, and stay in Yokohama. In particular, to whom come from abroad more than 17 countries, I would appreciate your participations after long long trips from your homeland to Yokohama. The first international workshop on "State of the Art in Nuclear Cluster Physics", called SOTANCP, was held in Strasbourg, France, in 2008, and the second one was held in Brussels, Belgium, in 2010. Then the third workshop is now held in Yokohama. In this period, we had the traditional 10th cluster conference in Debrecen, Hungary, in 2012. Thus we have the traditional cluster conference and SOTANCP, one after another, every two years. This obviously shows our field of nuclear cluster physics is very active and flourishing. It is for the first time in about 10 years to hold the international workshop on nuclear cluster physics in Japan, because the last cluster conference held in Japan was in Nara in 2003, about 10 years ago. The president in Nara conference was Prof. K. Ikeda, and the chairpersons were Prof. H. Horiuchi and Prof. I. Tanihata. I think, quite a lot of persons in this room had participated at the Nara conference. Since then, about ten years passed. So, this workshop has profound significance for our Japanese colleagues. The subjects of this workshop are to discuss "the state of the art in nuclear cluster physics" and also discuss the prospect of this field. In a couple of years, we saw significant progresses of this field both in theory and in experiment, which have brought better and new understandings on the clustering aspects in stable and unstable nuclei. I think, the concept of clustering has been more important than ever. This is true also in the

  7. Presidential address.

    PubMed

    Vohra, U

    1993-07-01

    The Secretary of India's Ministry of Health and Family Welfare serves as Chair of the Executive Council of the International Institute for Population Sciences in Bombay. She addressed its 35th convocation in 1993. Global population stands at 5.43 billion and increases by about 90 million people each year. 84 million of these new people are born in developing countries. India contributes 17 million new people annually. The annual population growth rate in India is about 2%. Its population size will probably surpass 1 billion by the 2000. High population growth rates are a leading obstacle to socioeconomic development in developing countries. Governments of many developing countries recognize this problem and have expanded their family planning programs to stabilize population growth. Asian countries that have done so and have completed the fertility transition include China, Japan, Singapore, South Korea, and Thailand. Burma, Malaysia, North Korea, Sri Lanka, and Vietnam have not yet completed the transition. Afghanistan, Bangladesh, Iran, Nepal, and Pakistan are half-way through the transition. High population growth rates put pressure on land by fragmenting finite land resources, increasing the number of landless laborers and unemployment, and by causing considerable rural-urban migration. All these factors bring about social stress and burden civic services. India has reduced its total fertility rate from 5.2 to 3.9 between 1971 and 1991. Some Indian states have already achieved replacement fertility. Considerable disparity in socioeconomic development exists among states and districts. For example, the states of Bihar, Madhya Pradesh, Rajasthan, and Uttar Pradesh have female literacy rates lower than 27%, while that for Kerala is 87%. Overall, infant mortality has fallen from 110 to 80 between 1981 and 1990. In Uttar Pradesh, it has fallen from 150 to 98, while it is at 17 in Kerala. India needs innovative approaches to increase contraceptive prevalence rates

  8. President's Address

    PubMed Central

    Craig, Maurice

    1928-01-01

    Conditions which experience has proved conducive to mental disturbance considered.—Suggestions as to their treatment.—A weakened inhibition, rather than any positive condition, is probably the most important factor in the production of the exhaustion psycho-neuroses or psychoses. This view is supported by the prophylactic value of giving for prolonged periods small doses of bromide to hypersensitive children or to highly-strung persons exposed to stress or tropical climate, etc.—Pavlov's work on the conditioned reflexes in dogs quoted in support of the author's clinical experience: Pavlov states that bromides should not be regarded as sedatives, diminishing the excitability of the central nervous system, but as simply regulating the nervous system by strengthening the intensity of internal inhibition. This agrees with the author's clinical experience, as small doses of bromide taken regularly over a period of many years do not diminish the mental powers but in fact increase them. Question of sleeplessness considered with regard to the way in which sedatives act. Most of these do not act as so-called “sleeping draughts”; research may ultimately show that their action is to strengthen a weakened inhibition and that sleep is only a secondary benefit.—Value of sedatives before and after surgical operation. Importance of toxæmia in the production of mental disorder; insomnia often precedes a toxic process and permits it to become active. The theory of weakened inhibition explains many problems; e.g., why certain brilliant children or adults break down and why at first there is no interference with their normal mental activity which only becomes involved as sleep and other bodily functions become affected; why a toxæmia may affect the nervous system of certain people; why a breakdown may follow over-stimulation or occur with advancing years; why some persons relapse when certain treatment is discontinued; why treatment should at times be continuous, and why

  9. Twenty Questions about Student Errors.

    ERIC Educational Resources Information Center

    Fisher, Kathleen M.; Lipson, Joseph Isaac

    1986-01-01

    Discusses the value of studying errors made by students in the process of learning science. Addresses 20 research questions dealing with student learning errors. Attempts to characterize errors made by students and clarify some terms used in error research. (TW)

  10. HPV Vaccine - Questions and Answers

    MedlinePlus

    ... and Media Resources News Newsletters Events Redirect for HPV Vaccine FAQ Recommend on Facebook Tweet Share Compartir ... to the address below. http://www.cdc.gov/hpv/parents/questions-answers.html File Formats Help: How ...

  11. Welcome Address

    NASA Astrophysics Data System (ADS)

    Kiku, H.

    2014-12-01

    Ladies and Gentlemen, It is an honor for me to present my welcome address in the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3), as the president of Kanto Gakuin University. Particularly to those from abroad more than 17 countries, I am very grateful for your participation after long long trips from your home to Yokohama. On the behalf of the Kanto Gakuin University, we certainly welcome your visit to our university and stay in Yokohama. First I would like to introduce Kanto Gakuin University briefly. Kanto Gakuin University, which is called KGU, traces its roots back to the Yokohama Baptist Seminary founded in 1884 in Yamate, Yokohama. The seminary's founder was Albert Arnold Bennett, alumnus of Brown University, who came to Japan from the United States to establish a theological seminary for cultivating and training Japanese missionaries. Now KGU is a major member of the Kanto Gakuin School Corporation, which is composed of two kindergartens, two primary schools, two junior high schools, two senior high schools as well as KGU. In this university, we have eight faculties with graduate school including Humanities, Economics, Law, Sciences and Engineering, Architecture and Environmental Design, Human and Environmental Studies, Nursing, and Law School. Over eleven thousands students are currently learning in our university. By the way, my major is the geotechnical engineering, and I belong to the faculty of Sciences and Engineering in my university. Prof. T. Yamada, here, is my colleague in the same faculty. I know that the nuclear physics is one of the most active academic fields in the world. In fact, about half of the participants, namely, more than 50 scientists, come from abroad in this conference. Moreover, I know that the nuclear physics is related to not only the other fundamental physics such as the elementary particle physics and astrophysics but also chemistry, medical sciences, medical cares, and radiation metrology

  12. Questions of wisdom.

    PubMed

    Schmidt Bunkers, Sandra

    2009-04-01

    In this column questions concerning wisdom are addressed, such as, what is wisdom? Can wisdom be taught in the academy? Several perspectives on wisdom from philosophy, education, business, and psychology are presented. Wisdom with creativity-creativity with wisdom is then explored through discussion of Parse's humanbecoming teaching-learning model and Laird Hamilton's life lessons learned from surfing, which he termed wisdom of the wave. The column concludes with consideration of the wise person.

  13. Opening Address

    NASA Astrophysics Data System (ADS)

    Crovini, L.

    1994-01-01

    Ladies and Gentlemen To quote Mr Jean Terrien: "Physics must be one step ahead of metrology". A long-serving Director of the BIPM, he said these words when visiting the IMGC in 1970 as a member of the scientific board of our Institute. At that time it was still an open question whether the IMGC should start research work on the absolute measurement of silicon lattice spacing. Mr Terrien underlined the revolutionary character of x-ray interferometry and, eventually, he caused the balance needle to lean towards the ... right direction. Mr Terrien correctly foresaw that, like Michelson's interferometer of 1880, x-ray interferometry could have a prominent place in today's science and technology. And while, in the first case, after more than a century we can see instruments based on electromagnetic wave interaction within every one's reach in laboratories and, sometimes, in workshops, in the second case, twenty-five years since the first development of an x-ray interferometer we can witness its role in nanometrology. Today and tomorrow we meet to discuss how to go beyond the sixth decimal place in the value of the Avogadro constant. We are aware that the quest for this achievement requires the cooperation of scientists with complementary capabilities. I am sure that the present workshop is a very good opportunity to present and discuss results and to improve and extend existing cooperation. The new adjustment of fundamental constants envisaged by the CODATA Task Group is redoubling scientists' efforts to produce competitive values of NA. The results of the measurements of the silicon lattice spacing in terms of an optical wavelength, which were available for the 1986 adjustment, combined with the determination of silicon molar volume, demonstrate how such an NA determination produces a consistent set of other constants and opens the way to a possible redefinition of the kilogram. We shall see in these two days how far we have progressed along this road. For us at the

  14. Answering Your Questions about AIDS.

    ERIC Educational Resources Information Center

    Kalichman, Seth C.

    This book focuses on AIDS education and answers 350 commonly asked questions about Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) taken from questions addressed to two major urban AIDS hotlines (Milwaukee, Wisconsin, and Houston, Texas). Chapter 1, "HIV - The Virus That Causes AIDS," discusses: the HIV…

  15. Immune modulation by non-hodgkin lymphoma in a patient with two primary intestinal T-cell lymphomas and long-standing celiac disease.

    PubMed

    Mühr-Wilkenshoff, F; Friedrich, M; Foss, H-D; Hummel, M; Zeitz, M; Daum, S

    2010-01-01

    Tumors may influence immunologic reactions. Here, we report on a 72-year-old patient who suffered from celiac disease (CD) that had been diagnosed 20 years before. Under a normal diet but without any evidence of enteropathy or CD-associated antibodies, the patient developed a jejunal T-cell lymphoma. It was resected due to perforation and four courses of IMVP-16 were added. The patient started and kept a strict gluten-free diet (GFD). Two years later, he presented with weight loss and a clonally divergent refractory sprue type II with loss of antigen (CD8; T-cell receptor-beta) expression in intraepithelial lymphocytes. At this time point, he showed high titers of CD-associated antibodies, although he was on a strict GFD. This case report highlights several questions: the missing enteropathy under a gluten-containing diet supports the notion of immune suppression in malignant diseases, especially non-Hodgkin lymphoma. Secondly, the patient developed an early form of a second independent T-cell lymphoma (refractory sprue type II) under a strict GFD, then with CD-associated antibodies, which raises the question whether the clonal intraepithelial lymphocytes were stimulating antibody production. Thus, the single detection of CD-associated antibodies in patients with CD is not itself proof of noncompliance with GFD.

  16. Republished: Respiratory microbiota: addressing clinical questions, informing clinical practice

    PubMed Central

    Rogers, Geraint B; Shaw, Dominick; Marsh, Robyn L; Carroll, Mary P; Serisier, David J; Bruce, Kenneth D

    2015-01-01

    Over the last decade, technological advances have revolutionised efforts to understand the role played by microbes in airways disease. With the application of ever more sophisticated techniques, the literature has become increasingly inaccessible to the non-specialist reader, potentially hampering the translation of these gains into improvements in patient care. In this article, we set out the key principles underpinning microbiota research in respiratory contexts and provide practical guidance on how best such studies can be designed, executed and interpreted. We examine how an understanding of the respiratory microbiota both challenges fundamental assumptions and provides novel clinical insights into lung disease, and we set out a number of important targets for ongoing research. PMID:26304986

  17. Questioning Many Mysteries

    NASA Astrophysics Data System (ADS)

    Martin, Sara F.

    2015-04-01

    The first section of this memoir queries my formative years. Indirectly I address the question, did my childhood and early years make a difference in my choice of career? Why and how did I begin my journey to becoming a scientist? Did I choose the field of solar astronomy or did circumstances dictate it for me? In the second section, I travel through my work environments and experiences, talking about interactions and aspects of being a scientist that do not appear in our research papers. What parts of my research were happenstances and what parts did I plan? What does it feel like to be on scientific quests? Using examples in my journey, I also turn to questions that have intrigued me throughout my sojourn as a solar astronomer. How do scientific discoveries come about? What factors lead to little discoveries? And what factors lead to major exciting discoveries? Are there timely questions we do not think to ask? How can small, seemingly scattered pieces of knowledge suddenly coalesce into a deeper understanding - what is called the "Aha!" experience - the times when our mental light switches on, and with child-like wonder we behold a "big picture"?

  18. Privacy Questions from Practicing School Nurses

    ERIC Educational Resources Information Center

    Bergren, Martha Dewey

    2004-01-01

    This Question and Answer (Q&A) article addresses practice issues related to school health records and school nursing documentation that were posed by school nurses in the field. Specifically, the questions addressed concern the following: education records, medication privacy issues, sharing of sensitive health information, privacy of…

  19. Keynote Address: Rev. Mark Massa

    ERIC Educational Resources Information Center

    Massa, Mark S.

    2011-01-01

    Rev. Mark S. Massa, S.J., is the dean and professor of Church history at the School of Theology and Ministry at Boston College. He was invited to give a keynote to begin the third Catholic Higher Education Collaborative Conference (CHEC), cosponsored by Boston College and Fordham University. Fr. Massa's address posed critical questions about…

  20. Recognizing Question Entailment for Medical Question Answering

    PubMed Central

    Abacha, Asma Ben; Dina, Demner-Fushman

    2016-01-01

    With the increasing heterogeneity and specialization of medical texts, automated question answering is becoming more and more challenging. In this context, answering a given medical question by retrieving similar questions that are already answered by human experts seems to be a promising solution. In this paper, we propose a new approach for the detection of similar questions based on Recognizing Question Entailment (RQE). In particular, we consider Frequently Asked Question (FAQs) as a valuable and widespread source of information. Our final goal is to automatically provide an existing answer if FAQ similar to a consumer health question exists. We evaluate our approach using consumer health questions received by the National Library of Medicine and FAQs collected from NIH websites. Our first results are promising and suggest the feasibility of our approach as a valuable complement to classic question answering approaches. PMID:28269825

  1. The Value Question in Metaphysics.

    PubMed

    Kahane, Guy

    2012-07-01

    Much seems to be at stake in metaphysical questions about, for example, God, free will or morality. One thing that could be at stake is the value of the universe we inhabit-how good or bad it is. We can think of competing philosophical positions as describing possibilities, ways the world might turn out to be, and to which value can be assigned. When, for example, people hope that God exists, or fear that we do not possess free will, they express attitudes towards these possibilities, attitudes that presuppose answers to questions about their comparative value. My aim in this paper is to distinguish these evaluative questions from related questions with which they can be confused, to identify structural constraints on their proper pursuit, and to address objections to their very coherence. Answers to such evaluative questions offer one measure of the importance of philosophical disputes.

  2. The Value Question in Metaphysics

    PubMed Central

    Kahane, Guy

    2012-01-01

    Much seems to be at stake in metaphysical questions about, for example, God, free will or morality. One thing that could be at stake is the value of the universe we inhabit—how good or bad it is. We can think of competing philosophical positions as describing possibilities, ways the world might turn out to be, and to which value can be assigned. When, for example, people hope that God exists, or fear that we do not possess free will, they express attitudes towards these possibilities, attitudes that presuppose answers to questions about their comparative value. My aim in this paper is to distinguish these evaluative questions from related questions with which they can be confused, to identify structural constraints on their proper pursuit, and to address objections to their very coherence. Answers to such evaluative questions offer one measure of the importance of philosophical disputes. PMID:23024399

  3. Questions, Questioning Techniques, and Effective Teaching.

    ERIC Educational Resources Information Center

    Wilen, William W., Ed.

    This book focuses on questioning techniques and strategies teachers may employ to make the difference between active and passive learning in the classroom. There are nine chapters: (1) Why Questions? (Ambrose A. Clegg, Jr.); (2) Review of Research on Questioning Techniques (Meredith D. Gall and Tom Rhody); (3) The Multidisciplinary World of…

  4. Posing Einstein's Question: Questioning Einstein's Pose.

    ERIC Educational Resources Information Center

    Topper, David; Vincent, Dwight E.

    2000-01-01

    Discusses the events surrounding a famous picture of Albert Einstein in which he poses near a blackboard containing a tensor form of his 10 field equations for pure gravity with a question mark after it. Speculates as to the content of Einstein's lecture and the questions he might have had about the equation. (Contains over 30 references.) (WRM)

  5. Ask Questions to Encourage Questions Asked

    ERIC Educational Resources Information Center

    belcastro, sarah-marie

    2017-01-01

    We delineate some types of structured practice (modeling, requests, feedback, and space-making) that help students learn to pose appropriate questions and to initiate exploration of those questions. Developing skills requires practice, so we suggest ways to embed structured practice into existing class sessions. Including structured practice is…

  6. Phrasal Paraphrase Based Question Reformulation for Archived Question Retrieval.

    PubMed

    Zhang, Yu; Zhang, Wei-Nan; Lu, Ke; Ji, Rongrong; Wang, Fanglin; Liu, Ting

    2013-01-01

    Lexical gap in cQA search, resulted by the variability of languages, has been recognized as an important and widespread phenomenon. To address the problem, this paper presents a question reformulation scheme to enhance the question retrieval model by fully exploring the intelligence of paraphrase in phrase-level. It compensates for the existing paraphrasing research in a suitable granularity, which either falls into fine-grained lexical-level or coarse-grained sentence-level. Given a question in natural language, our scheme first detects the involved key-phrases by jointly integrating the corpus-dependent knowledge and question-aware cues. Next, it automatically extracts the paraphrases for each identified key-phrase utilizing multiple online translation engines, and then selects the most relevant reformulations from a large group of question rewrites, which is formed by full permutation and combination of the generated paraphrases. Extensive evaluations on a real world data set demonstrate that our model is able to characterize the complex questions and achieves promising performance as compared to the state-of-the-art methods.

  7. Phrasal Paraphrase Based Question Reformulation for Archived Question Retrieval

    PubMed Central

    Lu, Ke; Ji, Rongrong; Wang, Fanglin; Liu, Ting

    2013-01-01

    Lexical gap in cQA search, resulted by the variability of languages, has been recognized as an important and widespread phenomenon. To address the problem, this paper presents a question reformulation scheme to enhance the question retrieval model by fully exploring the intelligence of paraphrase in phrase-level. It compensates for the existing paraphrasing research in a suitable granularity, which either falls into fine-grained lexical-level or coarse-grained sentence-level. Given a question in natural language, our scheme first detects the involved key-phrases by jointly integrating the corpus-dependent knowledge and question-aware cues. Next, it automatically extracts the paraphrases for each identified key-phrase utilizing multiple online translation engines, and then selects the most relevant reformulations from a large group of question rewrites, which is formed by full permutation and combination of the generated paraphrases. Extensive evaluations on a real world data set demonstrate that our model is able to characterize the complex questions and achieves promising performance as compared to the state-of-the-art methods. PMID:23805178

  8. Textbook Questions to Support Spatial Thinking: Differences in Spatiality by Question Location

    ERIC Educational Resources Information Center

    Jo, Injeong; Bednarz, Sarah W.

    2011-01-01

    This study investigates the location and varying spatiality of questions in geography textbooks. The results show that study questions posed in page margins address the three components of spatial thinking--concepts of space, using tools of representation, and processes of reasoning--more than questions in other locations within the text. Three…

  9. Who Asks the Questions?

    ERIC Educational Resources Information Center

    Hervey, Sheena

    2006-01-01

    From a very young age, children actively strive to make sense of their world through constant questioning. The ability to ask questions comes naturally for young children, but such natural inclination does not continue because it teachers who ask most of the questions. Sheena Hervey suggests that teaching students how to pose questions is a…

  10. Revisiting Routine Questions

    ERIC Educational Resources Information Center

    Hughes, Rebecca; Monaghan, John; Shingadia, Eisha; Vaughan, Stephen

    2006-01-01

    What is a routine question? The focus of this paper is routine questions and time (in years) since a hitherto routine question was last attempted by the solver. The data comes from undergraduate students' work on solving two calculus questions. The data was selected for reporting purposes because it is well documented and because it threw up…

  11. Questions of Chemistry.

    ERIC Educational Resources Information Center

    Pedrosa de Jesus, Helena; Teixeira-Dias, Jose J. C.; Watts, Mike

    2003-01-01

    Documents the use of student-generated questions as diagnostic of their willingness to engage in classroom interactions. Explores four ways of gathering students' written questions and their relative effectiveness. Examines students' capacity to design and present 'quality questions' and the extent to which these questions are indicative of…

  12. Question analysis for Indonesian comparative question

    NASA Astrophysics Data System (ADS)

    Saelan, A.; Purwarianti, A.; Widyantoro, D. H.

    2017-01-01

    Information seeking is one of human needs today. Comparing things using search engine surely take more times than search only one thing. In this paper, we analyzed comparative questions for comparative question answering system. Comparative question is a question that comparing two or more entities. We grouped comparative questions into 5 types: selection between mentioned entities, selection between unmentioned entities, selection between any entity, comparison, and yes or no question. Then we extracted 4 types of information from comparative questions: entity, aspect, comparison, and constraint. We built classifiers for classification task and information extraction task. Features used for classification task are bag of words, whether for information extraction, we used lexical, 2 previous and following words lexical, and previous label as features. We tried 2 scenarios: classification first and extraction first. For classification first, we used classification result as a feature for extraction. Otherwise, for extraction first, we used extraction result as features for classification. We found that the result would be better if we do extraction first before classification. For the extraction task, classification using SMO gave the best result (88.78%), while for classification, it is better to use naïve bayes (82.35%).

  13. Questioning cochlear amplification

    NASA Astrophysics Data System (ADS)

    van der Heijden, Marcel; Versteegh, Corstiaen P. C.

    2015-12-01

    Thirty years ago it was hypothesized that motile processes inject mechanical energy into cochlear traveling waves. This mechanical amplification, alternatively described as negative damping, is invoked to explain both the sensitivity and the nonlinear compression of cochlear responses. There is a recent trend to present cochlear amplification as an established fact, even though the evidence is at most circumstantial and several thorny problems have remained unresolved. We analyze several of these issues, and present new basilar membrane recordings that allowed us to quantify cochlear energy flow. Specifically, we address the following questions: (1) Does auditory sensitivity require narrowband amplification? (2) Has the "RC problem" (lowpass filtering of outer hair cell receptor potential) been resolved? (3) Can OHC motility improve auditory sensitivity? (4) Is there a net power gain between neighboring locations on the basilar membrane? The analyses indicate that mechanical amplification in the cochlea is neither necessary nor useful, and that realizing it by known forms of motility would reduce sensitivity rather than enhance it. Finally, our experimental data show that the peaking of the traveling wave is realized by focusing the acoustic energy rather than amplifying it. (Abbreviations. BM: basilar membrane; CF: characteristic frequency; IHC: inner hair cell; ME: middle ear; MT; mechanotransducer; OHC: outer hair cell; SPL: sound pressure level.)

  14. Risk Factor Analysis and the Youth Question

    ERIC Educational Resources Information Center

    France, Alan

    2008-01-01

    This paper is concerned with exploring how in late modernity the "youth question" is being addressed by public policy and what impact this is having on understandings of childhood and youth. Historically the youth question has been shaped by adult anxieties over youth delinquency and their problems of social integration. In late modernity, this is…

  15. Teaching Dystopias: The Value of Religious Questioning.

    ERIC Educational Resources Information Center

    Seabury, Marcia Bundy

    1995-01-01

    Argues that a true general education should encourage the exploration of religious questions. Describes the author's use of works showing dystopian societies based on existing values, such as Huxley's "Brave New World," to encourage students to rethink their assumptions and develop openness toward the questions that religions address. (22…

  16. Conscience in Childhood: Old Questions, New Answers

    ERIC Educational Resources Information Center

    Aksan, Nazan; Kochanska, Grazyna

    2005-01-01

    Although conscience has been the focus of reflection for centuries, fundamental questions regarding its organization have not been fully answered. To address those questions, the authors applied structural equation modeling techniques to longitudinal data comprising multiple behavioral measures of children's conscience, obtained in parallel…

  17. Exam Question Exchange.

    ERIC Educational Resources Information Center

    Alexander, John J.

    1979-01-01

    Describes an exam question which challenges college freshmen, enrolled in chemistry, to derive temperature dependence of an equilibrium constant. The question requires cognitive response at the level of synthesis. (Author/SA)

  18. Burning Questions about Calories.

    ERIC Educational Resources Information Center

    Keller, J. David; Berry, Kimberly A.

    2001-01-01

    Uses questioning techniques to teach about caloric consumption and weight gain. Starts with defining questions about calories and includes the stages of measuring calories, analyzing data, and conducting inquiry research. Includes directions for the experiment. (YDS)

  19. Questions in Reference Interviews.

    ERIC Educational Resources Information Center

    White, Marilyn Domas

    1998-01-01

    Characterizes the questioning behavior in reference interviews preceding delegated online searches of bibliographic databases and relates it to questioning behavior in other types of interviews/settings. Compares questions asked by the information specialist and those asked by the client; findings show the information specialist dominates the…

  20. Exam Question Exchange.

    ERIC Educational Resources Information Center

    Alexander, John J., Ed.

    1987-01-01

    Contains two articles relating to chemistry examination questions. One provides examples of how to sequence multiple choice questions so that partial credit may be given for some responses. The second includes a question and solution dealing with stereoisomerism as a result of free radical chlorination of a nonstereoisometic substance. (TW)

  1. Exam Question Exchange.

    ERIC Educational Resources Information Center

    Alexander, John J., Ed.

    1983-01-01

    Acceptable answers are provided for two chemistry questions. The first question is related to the prediction of the appearance of non-first-order proton nuclear magnetic resonance (NMR) spectra. The second question is related to extraterrestrial kinetic theory of gases. (JN)

  2. Listening and Questioning

    ERIC Educational Resources Information Center

    Haroutunian-Gordon, Sophie

    2007-01-01

    In the article that follows, I take up a debate that has arisen over the past three years concerning the following issue: Does every act of listening involve the listener in questioning? I argue that the answer to the questions is yes. I give background on the question and then consider one instance of listening that may suggest no role for…

  3. Making Questions Flow

    ERIC Educational Resources Information Center

    Rothstein, Dan; Santana, Luz; Minigan, Andrew P.

    2015-01-01

    Getting students to ask questions can feel like pulling teeth. How can teachers transform that feeling and create classrooms that come alive with questions? The authors, developers of the question formulation technique, suggest two simple changes: First, teachers need to give students both a structure and the opportunity to practice generating…

  4. Improving Student Question Classification

    ERIC Educational Resources Information Center

    Heiner, Cecily; Zachary, Joseph L.

    2009-01-01

    Students in introductory programming classes often articulate their questions and information needs incompletely. Consequently, the automatic classification of student questions to provide automated tutorial responses is a challenging problem. This paper analyzes 411 questions from an introductory Java programming course by reducing the natural…

  5. Measuring Victimization inside Prisons: Questioning the Questions

    ERIC Educational Resources Information Center

    Wolff, Nancy; Shi, Jing; Bachman, Ronet

    2008-01-01

    Violence and victimization inside the prison setting are accepted as facts, although the facts about their prevalence remain uncertain. Variation in the methods used to estimate rates of sexual and physical victimization contribute to the wide range in estimates appearing in the prison literature. This article focuses on the questions used in the…

  6. Question-Asking and Question-Exploring

    ERIC Educational Resources Information Center

    Sands, Lorraine; Carr, Margaret; Lee, Wendy

    2012-01-01

    The Centre of Innovation Research at Greerton Early Childhood Centre was characterised as a dispositional milieu where working theories were explored through a narrative research methodology. As the research progressed, the teachers at Greerton strengthened the way we were listening to, and watching out for young children's questions to enable…

  7. Asking questions with focus

    NASA Astrophysics Data System (ADS)

    Liu, Fang; Xu, Yi

    2004-05-01

    This study investigates how different interrogative meanings interact with focus in determining the overall F0 profile of a question. We recorded eight native speakers of Mandarin producing statements, yes-no questions with and without a question particle, wh questions, incredulous questions, and confirmation questions. In each sentence, either the initial, medial, final, or no word was focused. The tonal components of the sentences are all high, all rising, all low, or all falling. F0 contours were extracted by measuring every complete vocal period in the initial, medial, and final disyllabic words in each sentence. Preliminary results show that in both statements and questions, the pitch range of the focused words is expanded and that of the postfocus words suppressed (compressed and lowered). However, postfocus pitch-range suppression seems less extensive in questions than in statements, and in some question types than in others. Finally, an extra F0 rise is often observed in the final syllable of a question unless the syllable is the question particle which has the neutral tone. This is indicative of a high or rising boundary tone associated with the interrogative meaning, which seems to be superimposed on the tone of the sentence-final syllable. [Work supported by NIDCD DC03902.

  8. Unpark Those Questions

    ERIC Educational Resources Information Center

    Ness, Molly

    2013-01-01

    Whenever Mr. Henderson's 3rd grade students had a question that he couldn't immediately answer or that seemed off-topic, he asked them to write the question on a sticky note and place it on a poster dubbed the "Parking Lot." His intention was to find time later to answer those questions, but too often, he said, the parking lot…

  9. Purchasing Educational Materials--Questions from the Field.

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    2000-01-01

    Lists 16 questions to address when pondering the purchase of educational materials. Addressed are issues of educational potential, health and safety to children, age flexibility, potential for skill development, structural integrity, and adequate customer service. (SD)

  10. 1 Great Question

    ERIC Educational Resources Information Center

    Nethery, Carrie

    2011-01-01

    In this article, the author presents an ideal question that can take an art teacher and his or her students through all the levels of thought in Bloom's taxonomy--perfect for modeling the think-aloud process: "How many people is the artist inviting into this picture?" This great question always helps the students look beyond the obvious and dig…

  11. Let's Switch Questioning Around

    ERIC Educational Resources Information Center

    Tovani, Cris

    2015-01-01

    English teacher Cris Tovani knows from her experiences teaching elementary school that students are naturally curious. But, too often, students are so trained to be question answerers that by the time they reach high school, they no longer form questions of their own and instead focus on trying to figure out what answer the teacher wants. Tovani…

  12. Questions About the Oceans.

    ERIC Educational Resources Information Center

    Dubach, Harold W.; Taber, Robert W.

    This book was prompted by the success of a display mounted by the National Oceanographic Data Center at the 17th International Science Fair in 1966, which enabled visiting teachers and students to ask and receive answers to questions via teletype. The book contains one hundred questions typical of those asked, together with answers ranging in…

  13. Designing Great Hinge Questions

    ERIC Educational Resources Information Center

    Wiliam, Dylan

    2015-01-01

    According to author Dylan Wiliam, because lessons never go exactly as planned, teachers should build plan B into plan A. This involves designing a lesson with a "hinge" somewhere in the middle and using specific kinds of questions--what he calls hinge questions--to quickly assess students' understanding of a concept before moving on.…

  14. Problem of Questioning

    SciTech Connect

    2005-10-31

    Le Prof.Leprince-Ringuet, chercheur sur le plan scientifique, artistique et humain, parle de la remise en question des hommes et la remise en question scientifique fondamentale ou exemplaire- plusieurs personnes prennent la parole p.ex Jeanmairet, Adam, Gregory. Le Prof.Gregory clot la soirée en remerciant le Prof.Leprince-Ringuet

  15. Problem of Questioning

    ScienceCinema

    None

    2016-07-12

    Le Prof.Leprince-Ringuet, chercheur sur le plan scientifique, artistique et humain, parle de la remise en question des hommes et la remise en question scientifique fondamentale ou exemplaire- plusieurs personnes prennent la parole p.ex Jeanmairet, Adam, Gregory. Le Prof.Gregory clot la soirée en remerciant le Prof.Leprince-Ringuet

  16. What is a Question?

    NASA Technical Reports Server (NTRS)

    Knuth, Kevin H.; Clancy, Daniel (Technical Monitor)

    2002-01-01

    A given question can be defined in terms of the set of statements or assertions that answer it. Application of the logic of inference to this set of assertions allows one to derive the logic of inquiry among questions. There are interesting symmetries between the logics of inference and inquiry; where probability describes the degree to which a premise implies an assertion, there exists an analogous quantity that describes the bearing or relevance that a question has on an outstanding issue. These have been extended to suggest that the logic of inquiry results in functional relationships analogous to, although more general than, those found in information theory. Employing lattice theory, I examine in greater detail the structure of the space of assertions and questions demonstrating that the symmetries between the logical relations in each of the spaces derive directly from the lattice structure. Furthermore, I show that while symmetries between the spaces exist, the two lattices are not isomorphic. The lattice of assertions is described by a Boolean lattice 2(sup N) whereas the lattice of real questions is shown to be a sublattice of the free distributive lattice FD(N) = 2(sup 2(sup N)). Thus there does not exist a one-to-one mapping of assertions to questions, there is no reflection symmetry between the two spaces, and questions in general do not possess unique complements. Last, with these lattice structures in mind, I discuss the relationship between probability, relevance and entropy.

  17. Addressing Ozone Layer Depletion

    EPA Pesticide Factsheets

    Access information on EPA's efforts to address ozone layer depletion through regulations, collaborations with stakeholders, international treaties, partnerships with the private sector, and enforcement actions under Title VI of the Clean Air Act.

  18. Statin intolerance: more questions than answers.

    PubMed

    Guyton, John R; Campbell, Kristen B; Lakey, Wanda C

    2014-01-01

    The dramatic effectiveness of statins in improving the course of atherosclerotic cardiovascular disease tends to overshadow questions of statin intolerance. Thus after more than 25 years of clinical statin use, intolerance remains a poorly understood, frustrating issue for patients and providers. It has been extraordinarily difficult to define statin intolerance and its implications for clinical practice. Here, we briefly summarize current knowledge and raise questions that need to be addressed.

  19. EPA Subaward Frequent Questions

    EPA Pesticide Factsheets

    These answers to frequent questions (FQ) are intended to provide information to recipients of EPA financial assistance to help them understand EPA’s interpretations of the Uniform Grant Guidance (UGG) and EPA’s Subaward Policy.

  20. Exam Question Exchange.

    ERIC Educational Resources Information Center

    Alexander, John J.

    1980-01-01

    Provides exam questions and solutions for a problem in amplification sequence of reactions, and a problem in applying group theory techniques and making spectral assignments and structural determination by qualitative arguments in the bonding in metal complexes. (CS)

  1. Rubella: Questions and Answers

    MedlinePlus

    ... of special precautions. Does the MMR vaccine cause autism? There is no scientific evidence that measles, MMR, ... other vaccine causes or increases the risk of autism. The question about a possible link between MMR ...

  2. Perchlorate Questions and Answers

    MedlinePlus

    ... EPA's Interim Health Advisory for Perchlorate in Public Water Systems On January 8, 2009, the Environmental Protection ... thyroid hormone. Questions and Answers about EPA’s Drinking Water Findings If perchlorate is present in my drinking ...

  3. Panspermia asks new questions

    NASA Astrophysics Data System (ADS)

    Klyce, Brig

    2001-08-01

    There is a widespread sentiment that panspermia is uninteresting is because it does not answer fundamental questions about the origin of life. The strongest version of panspermia asks entirely new questions. While barriers to the acceptance of panspermia are falling and evidence supporting it is accumulating, the mere possibility of panspermia unhinges the Darwinian account of evolutionary progress. The new theory removes an issue dividing science and religion, but it requires an amendment to the big bang theory.

  4. How Effective Are Your Questions?

    ERIC Educational Resources Information Center

    Partin, Ronald L.

    1979-01-01

    Guidelines are given to the teacher on using questions to improve classroom discussions. Included are: reasons for using questions, ways to ask questions and acknowledge students' responses, and types of questions which should and should not be used. (SJL)

  5. Using Notable Children's Literature and Questioning Techniques to Enhance Comprehension.

    ERIC Educational Resources Information Center

    Poole, Gary; Poole, Scott

    Intended for language arts teachers of the upper elementary grades, this guide suggests vocabulary and discussion questions for teaching novels. The questions are on an inferential level of interpretation, rather than literal, and address such topics as style, technique, and plot development. Novels for which questions are provided are: (1)…

  6. Critical Questions about Early Intervention and Early Childhood Special Education

    ERIC Educational Resources Information Center

    Winer, Abby; Hebbeler, Kathy; Nelson, Robin; Gundler, Darla; Cate, Debbie; Hudson, Laura; Taylor, Cornelia; Peters, Mary Louise

    2015-01-01

    What is a high-quality statewide data system? One characteristic is that it provides the information needed to address important questions about early intervention and early childhood special education. But what are those questions? What questions should data users, such as program directors, advocates, and policymakers, be asking? The Center for…

  7. Addressing Social Issues.

    ERIC Educational Resources Information Center

    Schoebel, Susan

    1991-01-01

    Maintains that advertising can help people become more aware of social responsibilities. Describes a successful nationwide newspaper advertising competition for college students in which ads address social issues such as literacy, drugs, teen suicide, and teen pregnancy. Notes how the ads have helped grassroots programs throughout the United…

  8. Invitational Addresses, 1965.

    ERIC Educational Resources Information Center

    Gates, Arthur I.; And Others

    The full texts of invitational addresses given at the 1965 International Reading Association (IRA) Convention in Detroit, Michigan, by six recipients of IRA citation awards are presented. Gates suggests steps IRA should take to revive and redirect reading research. McCallister discusses the implications of the changing and expanding vocabulary of…

  9. States Address Achievement Gaps.

    ERIC Educational Resources Information Center

    Christie, Kathy

    2002-01-01

    Summarizes 2 state initiatives to address the achievement gap: North Carolina's report by the Advisory Commission on Raising Achievement and Closing Gaps, containing an 11-point strategy, and Kentucky's legislation putting in place 10 specific processes. The North Carolina report is available at www.dpi.state.nc.us.closingthegap; Kentucky's…

  10. Addressing Sexual Harassment

    ERIC Educational Resources Information Center

    Young, Ellie L.; Ashbaker, Betty Y.

    2008-01-01

    This article discusses ways on how to address the problem of sexual harassment in schools. Sexual harassment--simply defined as any unwanted and unwelcome sexual behavior--is a sensitive topic. Merely providing students, parents, and staff members with information about the school's sexual harassment policy is insufficient; schools must take…

  11. Addressing NCDs through research and capacity building in LMICs: lessons learned from tobacco control

    PubMed Central

    Sturke, Rachel; Vorkoper, Susan; Duncan, Kalina; Levintova, Marya; Parascondola, Mark

    2016-01-01

    Confronting the global non-communicable diseases (NCDs) crisis requires a critical mass of scientists who are well versed in regional health problems and understand the cultural, social, economic, and political contexts that influence the effectiveness of interventions. Investments in global NCD research must be accompanied by contributions to local research capacity. The National Institutes of Health (NIH) and the Fogarty International Center have a long-standing commitment to supporting research capacity building and addressing the growing burden of NCDs in low- and middle-income countries. One program in particular, the NIH International Tobacco and Health Research and Capacity Building Program (TOBAC program), offers an important model for conducting research and building research capacity simultaneously. This article describes the lessons learned from this unique funding model and demonstrates how a relatively modest investment can make important contributions to scientific evidence and capacity building that could inform ongoing and future efforts to tackle the global burden of NCDs. PMID:27545455

  12. Addressing NCDs through research and capacity building in LMICs: lessons learned from tobacco control.

    PubMed

    Sturke, Rachel; Vorkoper, Susan; Duncan, Kalina; Levintova, Marya; Parascondola, Mark

    2016-01-01

    Confronting the global non-communicable diseases (NCDs) crisis requires a critical mass of scientists who are well versed in regional health problems and understand the cultural, social, economic, and political contexts that influence the effectiveness of interventions. Investments in global NCD research must be accompanied by contributions to local research capacity. The National Institutes of Health (NIH) and the Fogarty International Center have a long-standing commitment to supporting research capacity building and addressing the growing burden of NCDs in low- and middle-income countries. One program in particular, the NIH International Tobacco and Health Research and Capacity Building Program (TOBAC program), offers an important model for conducting research and building research capacity simultaneously. This article describes the lessons learned from this unique funding model and demonstrates how a relatively modest investment can make important contributions to scientific evidence and capacity building that could inform ongoing and future efforts to tackle the global burden of NCDs.

  13. Addressing dysfunctional relations among healthcare teams: improving team cooperation through applied organizational theories.

    PubMed

    Horwitz, Sujin K; Horwitz, Irwin B; Barshes, Neal R

    2011-01-01

    Previous research has demonstrated that communication failure and interpersonal conflicts are significant impediments among health-care teams to assess complex information and engage in the meaningful collaboration necessary for optimizing patient care. Despite the prolific research on the role of effective teamwork in accomplishing complex tasks, such findings have been traditionally applied to business organizations and not medical contexts. This chapter, therefore, reviews and applies four theories from the fields of organizational behavior (OB) and organization development (OD) as potential means for improving team interaction in health-care contexts. This study is unique in its approach as it addresses the long-standing problems that exist in team communication and cooperation in health-care teams by applying well-established theories from the organizational literature. The utilization and application of the theoretical constructs discussed in this work offer valuable means by which the efficacy of team work can be greatly improved in health-care organizations.

  14. Systemic Sclerosis: Commonly Asked Questions by Rheumatologists

    PubMed Central

    Young, Amber; Khanna, Dinesh

    2016-01-01

    Systemic sclerosis is a rare autoimmune disorder with significant morbidity and mortality due to multi-organ system involvement. Early diagnosis and screening for organ involvement is critical as earlier treatment appears to improve function and may impact mortality. The purpose of this article is to address some of the commonly asked questions by rheumatologists on systemic sclerosis. PMID:25807095

  15. Survey Questions Answered Only by Psychosocial Experts.

    ERIC Educational Resources Information Center

    American Journal on Mental Retardation, 2000

    2000-01-01

    Twelve tables provide a breakdown of answers to a survey responded to by 48 experts in the psychosocial treatment of psychiatric and behavioral problems in people with mental retardation. Questions address treatment of self-injurious or aggressive behavior, specific psychiatric disorders, specific target symptoms, use of applied behavior analysis…

  16. Evolution, Creationism, and the Courts: 20 Questions

    ERIC Educational Resources Information Center

    Moore, Randy; Miksch, Karen L.

    2003-01-01

    The teaching of evolution and creationism is controversial to many people in the United States. Knowledge of the many important court-decisions about the teaching of evolution and creationism in the United States can be used not only to resist anti-evolution activities of creationists, but also to help teachers address questions about the teaching…

  17. Computers into Classrooms: More Questions than Answers.

    ERIC Educational Resources Information Center

    Beynon, John, Ed.; Mackay, Hughie, Ed.

    This is one of a series of three books addressing the question of the nature of technological literacy. This volume, consisting of an introduction, an epilogue, and 12 chapters, focuses on classrooms and classroom processes involving computers and deals directly with teacher and student usage of microcomputers in teaching and learning. The 12…

  18. Survey Questions Answered Only by Medication Experts.

    ERIC Educational Resources Information Center

    American Journal on Mental Retardation, 2000

    2000-01-01

    Fifty-eight tables provide a breakdown of answers to a survey responded to by 45 experts in the medication treatment of psychiatric and behavioral problems in people with mental retardation. Questions address treatment of specific disorders, ratings of various medications for specific disorders or symptoms, and preferences in mood stabilizers,…

  19. Questioning Ohio's Loyalty Requirement

    ERIC Educational Resources Information Center

    O'Neil, Robert M.

    2006-01-01

    Beginning this past summer, all new employees at some Ohio public universities, including those accepting teaching positions, are being confronted with politically sensitive and intrusive questions. In addition to the "Have you solicited any individual for membership in an organization on the U.S. Department of State Terrorist…

  20. A Question of Character

    ERIC Educational Resources Information Center

    Stuart, Reginald

    2010-01-01

    When intern placement veteran Jacqueline Perkins begins counseling students at Florida A&M University (FAMU) about their prospects for getting well-paying, security-related jobs with the federal government, she confronts the 800-pound gorilla in the room--the question of whether a student has been convicted of or pleaded guilty to a…

  1. Exam Question Exchange.

    ERIC Educational Resources Information Center

    Alexander, John J., Ed.

    1978-01-01

    Two exam questions are presented. One suitable for advanced undergraduate or beginning graduate courses in organic chemistry, is on equivalent expressions for the description of several pericyclic reactions. The second, for general chemistry students, asks for an estimation of the rate of decay of a million-year-old Uranium-238 sample. (BB)

  2. My Favorite Exam Question

    ERIC Educational Resources Information Center

    Styer, Dan

    2015-01-01

    My favorite exam question comes from the final exam in an introductory mechanics course: "A rolling 31 ton railroad boxcar collides with a stationary flatcar. The coupling mechanism activates so the cars latch together and roll down the track attached. Of the initial kinetic energy, 38% dissipates as heat, sound, vibrations, mechanical…

  3. Asking Questions about Participation

    ERIC Educational Resources Information Center

    Davies, Ian; Flanagan, Bernie; Hogarth, Sylvia; Mountford, Paula; Philpott, Jenny

    2009-01-01

    We raise questions about young people's participation in light of findings from a project ("Democracy through Citizenship") funded by the Joseph Rowntree Reform Trust Limited, and managed by the Institute for Citizenship. Following a six-month feasibility study the project took place over a three-year period in one local authority in the…

  4. Asking the Right Questions

    ERIC Educational Resources Information Center

    Lord, Rob

    2011-01-01

    As a student teacher at Nottingham Trent University, the author explored the issues surrounding children asking investigable questions in science and the repertoire of strategies that could be employed by teachers in the classroom to support this process. His project was carried out in an inner-city primary school in Nottingham. The four focus…

  5. The Compensation Question

    ERIC Educational Resources Information Center

    Richwine, Jason; Biggs, Andrew; Mishel, Lawrence; Roy, Joydeep

    2012-01-01

    Over the past few years, as cash-strapped states and school districts have faced tough budget decisions, spending on teacher compensation has come under the microscope. The underlying question is whether, when you take everything into account, today's teachers are fairly paid, underpaid, or overpaid. In this forum, two pairs of respected…

  6. What Is the Question?

    ERIC Educational Resources Information Center

    Woodruff, Melba D.

    Second language educators need to examine in greater depth the learning processes of young children in order to provide them with the kind of teaching they need in order to really learn. This means searching other fields to learn as much as possible about: questioning strategies and the development of critical thinking skills; hemispheric…

  7. That Is the Question.

    ERIC Educational Resources Information Center

    Korsunsky, Syd

    2002-01-01

    Describes the author's evolution from a teacher set in his ways to one who adapted to students' voices. Contends that classrooms need to be environments where students are able to ask their own questions. Explains that key elements of such an environment include the following: interviews; mini-lessons; multi-genre projects; literature circles;…

  8. Questioning and Experimentation

    ERIC Educational Resources Information Center

    Mutanen, Arto

    2014-01-01

    The paper is a philosophical analysis of experimentation. The philosophical framework of the analysis is the interrogative model of inquiry developed by Hintikka. The basis of the model is explicit and well-formed logic of questions and answers. The framework allows us to formulate a flexible logic of experimentation. In particular, the formulated…

  9. Questioning in the Classroom.

    ERIC Educational Resources Information Center

    Hyman, Ronald T.

    This study investigates the pattern of teacher questioning regarding three elements: sequence, student respondent, and cognitive process. The rationale for this type of teaching rests on the claims for teaching students the process of critical (reflective) thinking. In this type of teaching it is necessary to have data before the students. Only…

  10. Big questions about the universe

    NASA Astrophysics Data System (ADS)

    Stavinschi, Magda

    2011-06-01

    Astronomy is not only a branch of science but also an important part of the culture and civilisations of peoples. Starting with archeoastronomy to the present day, it has always contributed to a better understanding of life, of humanity. After 400 years of modern astronomy, it still addresses major problems such as: Why there is something rather than nothing? Why is nature comprehensible to humans? How is cosmos related to humanity? Do multiverses exist? Is there life on other planets? Are we alone in the universe? Does the universe have a beginning? If so, what does it mean? How did the universe originate? All these questions are a challenge for interdisciplinary and transdisciplinary investigations, for philosophers, physicists, cosmologists, mathematicians, theologians. The new insights gained by pursuing in depth these common investigations will shape the society we live in and have important consequences on the future we are creating.

  11. Content Addressable Memory Project

    DTIC Science & Technology

    1990-11-01

    The Content Addressable M1-emory Project consists of the development of several experimental software systems on an AMT Distributed Array Processor...searching (database) compiler algorithms memory management other systems software) Linear C is an unlovely hybrid language which imports the CAM...memory from AMT’s operating system for the DAP; how- ever, other than this limitation, the memory management routines work exactly as their C counterparts

  12. Les questions de migrations internationales

    NASA Astrophysics Data System (ADS)

    Samman, Mouna Liliane

    1993-03-01

    International migrations have growing implications for both countries of origin and countries of destination. In the latter, the presence of foreigners and of members of their families today creates problems of integration, causes argument and brings mounting xenophobia. Paralleling political, economic and social measures taken by public authorities to respond to these difficulties, education needs to assist in defusing the resulting social tensions by preparing the minds of learners and helping to develop new attitudes. In particular, when educational programmes address questions of international migration, these should be treated in the framework of historical evolution so that their real significance and their true temporal and spatial dimensions become apparent. It is also important that the growing interdependence between countries should be made plain, that national history should be placed in its international context, and that the true consequences of these developments should be made clear. In this context, learners need to be acquainted with Human Rights, thereby stressing universal moral values and the role of the individual. Lastly, questions relating to international migration are usually presented in the media in a selective and partial manner, and the young people who take in this information often accept the hasty judgments which are made of situations as proven facts. This is why all teaching about international migration needs to be considered or reconsidered in the light of the complementary or competing actions of the media.

  13. Answering Key Fuel Cycle Questions

    SciTech Connect

    Piet, S.J.; Dixon, B.W.; Bennett, R.G.; Smith, J.D.; Hill, R.N.

    2004-10-03

    Given the range of fuel cycle goals and criteria, and the wide range of fuel cycle options, how can the set of options eventually be narrowed in a transparent and justifiable fashion? It is impractical to develop all options. We suggest an approach that starts by considering a range of goals for the Advanced Fuel Cycle Initiative (AFCI) and then posits seven questions, such as whether Cs and Sr isotopes should be separated from spent fuel and, if so, what should be done with them. For each question, we consider which of the goals may be relevant to eventually providing answers. The AFCI program has both ''outcome'' and ''process'' goals because it must address both waste already accumulating as well as completing the fuel cycle in connection with advanced nuclear power plant concepts. The outcome objectives are waste geologic repository capacity and cost, energy security and sustainability, proliferation resistance, fuel cycle economics, and safety. The process objectives are rea diness to proceed and adaptability and robustness in the face of uncertainties.

  14. Knowledge based question answering

    SciTech Connect

    Pazzani, M.J.; Engelman, C.

    1983-01-01

    The natural language database query system incorporated in the Knobs Interactive Planning System comprises a dictionary driven parser, APE-II, and script interpreter whch yield a conceptual dependency as a representation of the meaning of user input. A conceptualisation pattern matching production system then determines and executes a procedure for extracting the desired information from the database. In contrast to syntax driven q-a systems, e.g. those based on atn parsers, APE-II is driven bottom-up by expectations associated with word meanings. The goals of this approach include utilising similar representations for questions with similar meanings but widely varying surface structures, developing a powerful mechanism for the disambiguation of words with multiple meanings and the determination of pronoun referents, answering questions which require inferences to be understood, and interpreting ellipses and ungrammatical statements. The Knobs demonstration system is an experimental, expert system for air force mission planning applications. 16 refs.

  15. Quantum theory from questions

    NASA Astrophysics Data System (ADS)

    Höhn, Philipp Andres; Wever, Christopher S. P.

    2017-01-01

    We reconstruct the explicit formalism of qubit quantum theory from elementary rules on an observer's information acquisition. Our approach is purely operational: we consider an observer O interrogating a system S with binary questions and define S 's state as O 's "catalog of knowledge" about S . From the rules we derive the state spaces for N elementary systems and show that (a) they coincide with the set of density matrices over an N -qubit Hilbert space C2N; (b) states evolve unitarily under the group PSU (2N) according to the von Neumann evolution equation; and (c) O 's binary questions correspond to projective Pauli operator measurements with outcome probabilities given by the Born rule. As a by-product, this results in a propositional formulation of quantum theory. Aside from offering an informational explanation for the theory's architecture, the reconstruction also unravels previously unnoticed structural insights. We show that, in a derived quadratic information measure, (d) qubits satisfy inequalities which bound the information content in any set of mutually complementary questions to 1 bit; and (e) maximal sets of mutually complementary questions for one and two qubits must carry precisely 1 bit of information in pure states. The latter relations constitute conserved informational charges which define the unitary groups and, together with their conservation conditions, the sets of pure quantum states. These results highlight information as a "charge of quantum theory" and the benefits of this informational approach. This work emphasizes the sufficiency of restricting to an observer's information to reconstruct the theory and completes the quantum reconstruction initiated in a companion paper (P. Höhn, arXiv:1412.8323).

  16. Answering Key Fuel Cycle Questions

    SciTech Connect

    Steven J. Piet; Brent W. Dixon; J. Stephen Herring; David E. Shropshire; Mary Lou Dunzik-Gougar

    2003-10-01

    The Advanced Fuel Cycle Initiative (AFCI) program has both “outcome” and “process” goals because it must address both waste already accumulating as well as completing the fuel cycle in connection with advanced nuclear power plant concepts. The outcome objectives are waste geological repository capacity and cost, energy security and sustainability, proliferation resistance, fuel cycle economics, and safety. The process objectives are readiness to proceed and adaptability and robustness in the face of uncertainties. A classic decision-making approach to such a multi-attribute problem would be to weight individual quantified criteria and calculate an overall figure of merit. This is inappropriate for several reasons. First, the goals are not independent. Second, the importance of different goals varies among stakeholders. Third, the importance of different goals is likely to vary with time, especially the “energy future.” Fourth, some key considerations are not easily or meaningfully quantifiable at present. Instead, at this point, we have developed 16 questions the AFCI program should answer and suggest an approach of determining for each whether relevant options improve meeting each of the program goals. We find that it is not always clear which option is best for a specific question and specific goal; this helps identify key issues for future work. In general, we suggest attempting to create as many win-win decisions (options that are attractive or neutral to most goals) as possible. Thus, to help clarify why the program is exploring the options it is, and to set the stage for future narrowing of options, we have developed 16 questions, as follows: · What are the AFCI program goals? · Which potential waste disposition approaches do we plan for? · What are the major separations, transmutation, and fuel options? · How do we address proliferation resistance? · Which potential energy futures do we plan for? · What potential external triggers do we

  17. Bioreactors Addressing Diabetes Mellitus

    PubMed Central

    Minteer, Danielle M.; Gerlach, Jorg C.

    2014-01-01

    The concept of bioreactors in biochemical engineering is a well-established process; however, the idea of applying bioreactor technology to biomedical and tissue engineering issues is relatively novel and has been rapidly accepted as a culture model. Tissue engineers have developed and adapted various types of bioreactors in which to culture many different cell types and therapies addressing several diseases, including diabetes mellitus types 1 and 2. With a rising world of bioreactor development and an ever increasing diagnosis rate of diabetes, this review aims to highlight bioreactor history and emerging bioreactor technologies used for diabetes-related cell culture and therapies. PMID:25160666

  18. Bioreactors addressing diabetes mellitus.

    PubMed

    Minteer, Danielle M; Gerlach, Jorg C; Marra, Kacey G

    2014-11-01

    The concept of bioreactors in biochemical engineering is a well-established process; however, the idea of applying bioreactor technology to biomedical and tissue engineering issues is relatively novel and has been rapidly accepted as a culture model. Tissue engineers have developed and adapted various types of bioreactors in which to culture many different cell types and therapies addressing several diseases, including diabetes mellitus types 1 and 2. With a rising world of bioreactor development and an ever increasing diagnosis rate of diabetes, this review aims to highlight bioreactor history and emerging bioreactor technologies used for diabetes-related cell culture and therapies.

  19. Content addressable memory project

    NASA Technical Reports Server (NTRS)

    Hall, J. Storrs; Levy, Saul; Smith, Donald E.; Miyake, Keith M.

    1992-01-01

    A parameterized version of the tree processor was designed and tested (by simulation). The leaf processor design is 90 percent complete. We expect to complete and test a combination of tree and leaf cell designs in the next period. Work is proceeding on algorithms for the computer aided manufacturing (CAM), and once the design is complete we will begin simulating algorithms for large problems. The following topics are covered: (1) the practical implementation of content addressable memory; (2) design of a LEAF cell for the Rutgers CAM architecture; (3) a circuit design tool user's manual; and (4) design and analysis of efficient hierarchical interconnection networks.

  20. Building technology services that address student needs.

    PubMed

    Le Ber, Jeanne M; Lombardo, Nancy T; Wimmer, Erin

    2015-01-01

    A 16-question technology use survey was conducted to assess incoming health sciences students' knowledge of and interest in current technologies, and to identify student device and tool preferences. Survey questions were developed by colleagues at a peer institution and then edited to match this library's student population. Two years of student responses have been compiled, compared, and reviewed as a means for informing library decisions related to technology and resource purchases. Instruction and event programming have been revised to meet student preferences. Based on the number of students using Apple products, librarians are addressing the need to become more proficient with this platform.

  1. Addressing Environmental Health Inequalities

    PubMed Central

    Gouveia, Nelson

    2016-01-01

    Environmental health inequalities refer to health hazards disproportionately or unfairly distributed among the most vulnerable social groups, which are generally the most discriminated, poor populations and minorities affected by environmental risks. Although it has been known for a long time that health and disease are socially determined, only recently has this idea been incorporated into the conceptual and practical framework for the formulation of policies and strategies regarding health. In this Special Issue of the International Journal of Environmental Research and Public Health (IJERPH), “Addressing Environmental Health Inequalities—Proceedings from the ISEE Conference 2015”, we incorporate nine papers that were presented at the 27th Conference of the International Society for Environmental Epidemiology (ISEE), held in Sao Paulo, Brazil, in 2015. This small collection of articles provides a brief overview of the different aspects of this topic. Addressing environmental health inequalities is important for the transformation of our reality and for changing the actual development model towards more just, democratic, and sustainable societies driven by another form of relationship between nature, economy, science, and politics. PMID:27618906

  2. Questions, Relatives, and Minimal Projection.

    ERIC Educational Resources Information Center

    Demuth, Katherine

    1995-01-01

    This article examines the acquisition of wh-questions and relative clauses in Sesotho, a language with no wh-movement in either questions or relatives, and in which wh-questions must be clefted. (10 references) (JL)

  3. The Art of Asking Questions.

    ERIC Educational Resources Information Center

    Sykes, Rosetta A.

    1979-01-01

    A rationale is given for the use of questioning techniques and strategies in classroom instruction. B. Bloom's Taxonomy of Educational Objectives is presented as one framework for questions. Five pitfalls, including avoiding vague questions and personal pronouns, are discussed. (CL)

  4. To Question or Not to Question: That Seems to Be the Question.

    ERIC Educational Resources Information Center

    Bradtmueller, Weldon G.; Egan, James B.

    Research on the effects of questioning in the classroom has explored the placement, timing, type, and social impact of questions. Principles of good questioning include the following: (1) well-stated questions should be concise, clear, and complete; (2) questions should be topical in nature, requiring a complex answer; (3) yes or no questions…

  5. Questioning and Experimentation

    NASA Astrophysics Data System (ADS)

    Mutanen, Arto

    2014-08-01

    The paper is a philosophical analysis of experimentation. The philosophical framework of the analysis is the interrogative model of inquiry developed by Hintikka. The basis of the model is explicit and well-formed logic of questions and answers. The framework allows us to formulate a flexible logic of experimentation. In particular, the formulated model can be interpreted realistically. Moreover, the model demonstrates an explicit logic of knowledge acquisition. So, the natural extension of the model is to apply it to an analysis of the learning process.

  6. From Question Answering to Visual Exploration

    SciTech Connect

    McColgin, Dave W.; Gregory, Michelle L.; Hetzler, Elizabeth G.; Turner, Alan E.

    2006-08-11

    Research in Question Answering has focused on the quality of information retrieval or extraction using the metrics of precision and recall to judge success; these metrics drive toward finding the specific best answer(s) and are best supportive of a lookup type of search. These do not address the opportunity that users? natural language questions present for exploratory interactions. In this paper, we present an integrated Question Answering environment that combines a visual analytics tool for unstructured text and a state-of-the-art query expansion tool designed to compliment the cognitive processes associated with an information analysts work flow. Analysts are seldom looking for factoid answers to simple questions; their information needs are much more complex in that they may be interested in patterns of answers over time, conflicting information, and even related non-answer data may be critical to learning about a problem or reaching prudent conclusions. In our visual analytics tool, questions result in a comprehensive answer space that allows users to explore the variety within the answers and spot related information in the rest of the data. The exploratory nature of the dialog between the user and this system requires tailored evaluation methods that better address the evolving user goals and counter cognitive biases inherent to exploratory search tasks.

  7. Content addressable memory project

    NASA Technical Reports Server (NTRS)

    Hall, Josh; Levy, Saul; Smith, D.; Wei, S.; Miyake, K.; Murdocca, M.

    1991-01-01

    The progress on the Rutgers CAM (Content Addressable Memory) Project is described. The overall design of the system is completed at the architectural level and described. The machine is composed of two kinds of cells: (1) the CAM cells which include both memory and processor, and support local processing within each cell; and (2) the tree cells, which have smaller instruction set, and provide global processing over the CAM cells. A parameterized design of the basic CAM cell is completed. Progress was made on the final specification of the CPS. The machine architecture was driven by the design of algorithms whose requirements are reflected in the resulted instruction set(s). A few of these algorithms are described.

  8. Automatically Classifying Question Types for Consumer Health Questions

    PubMed Central

    Roberts, Kirk; Kilicoglu, Halil; Fiszman, Marcelo; Demner-Fushman, Dina

    2014-01-01

    We present a method for automatically classifying consumer health questions. Our thirteen question types are designed to aid in the automatic retrieval of medical answers from consumer health resources. To our knowledge, this is the first machine learning-based method specifically for classifying consumer health questions. We demonstrate how previous approaches to medical question classification are insufficient to achieve high accuracy on this task. Additionally, we describe, manually annotate, and automatically classify three important question elements that improve question classification over previous techniques. Our results and analysis illustrate the difficulty of the task and the future directions that are necessary to achieve high-performing consumer health question classification. PMID:25954411

  9. The Gentle Art of Questioning: Writing Great Clicker Questions

    NASA Astrophysics Data System (ADS)

    Chasteen, Stephanie

    2012-02-01

    How does a teacher use questioning effectively? This workshop will focus on writing those questions that engage students, spark their curiosity, help recap material, give you insight into their thinking, or help them learn critical ideas in physics. We will focus on ``peer instruction'' -- a research-tested method of requiring students to discuss challenging questions with one another. We will investigate the surprising power of multiple-choice questions to achieve critical thinking skills. Finally, we will look at writing questions that align with our goals for students, discuss the elements of effective questions, and practice writing questions and work on improving them.

  10. `Question Moments': A Rolling Programme of Question Opportunities in Classroom Science

    NASA Astrophysics Data System (ADS)

    Pedrosa-de-Jesus, Helena; Leite, Sara; Watts, Mike

    2016-06-01

    This naturalistic study integrates specific `question moments' into lesson plans to increase pupils' classroom interactions. A range of tools explored students' ideas by providing students with opportunities to ask and write questions. Their oral and written outcomes provide data on individual and group misunderstandings. Changes to the schedule of lessons were introduced to explore these questions and address disparities. Flexible lesson planning over 14 lessons across a 4-week period of high school chemistry accommodated students' contributions and increased student participation, promoted inquiring and individualised teaching, with each teaching strategy feeding forward into the next.

  11. Cataract, cost: curious questions.

    PubMed

    Moran, D J

    1999-02-01

    An investigation of the pricing of implantable prosthetic devices in Australia reveals some alarming practices. A governmental mechanism exists to prop up the pricing of 7500 listed devices to levels that are unacceptably high by world standards. Private hospitals and doctors are able, legally, to profit by marking up the cost of these devices from the market price to this artificially inflated price. Even the open market prices of implantable prosthetic items, such as intra-ocular lenses, are high by international standards. In a time of budgetary constraint for health spending and rapidly increasing use of these devices, these issues urgently need to be addressed in Australia.

  12. Engaging Students through Effective Questions

    ERIC Educational Resources Information Center

    Neal, Mary-Anne

    2011-01-01

    In what ways might questioning techniques improve student learning? What kinds of questions enable educators to tap into different parts of the cognitive domain? How can questions engage students when their attention begins to wander? Many questions at the lower levels of Bloom's Taxonomy--particularly knowledge and comprehension--are closed-ended…

  13. Improving Multiple-Choice Questions

    ERIC Educational Resources Information Center

    Torres, Cristina; Lopes, Ana Paula; Babo, Lurdes; Azevedo, Jose

    2011-01-01

    A MC (multiple-choice) question can be defined as a question in which students are asked to select one alternative from a given set of alternatives in response to a question stem. The objective of this paper is to analyse if MC questions may be considered as an interesting alternative for assessing knowledge, particularly in the mathematics area,…

  14. Unproven (questionable) cancer therapies.

    PubMed Central

    Brigden, M L

    1995-01-01

    More than half of all cancer patients use some form of alternative treatment during the course of their illness. Alternative therapies are often started early in patients' illness, and their use is frequently not acknowledged to health care professionals. Some alternative therapies are harmful, and their promoters may be fraudulent. Persons who try alternative cancer therapies may not be poorly educated but may ultimately abandon conventional treatment. Recent attention has focused on aspects of questionable therapies that make these treatments attractive to patients and that may be perceived as being deficient in the practice of conventional health care professionals. Physicians with patients with cancer should always make sure that unproven therapies are discussed early in the therapeutic relationship. They should also attempt to be aware of alternative therapies that are in vogue in their particular geographic area. PMID:8533410

  15. [Keynote address: Climate change

    SciTech Connect

    Forrister, D.

    1994-12-31

    Broadly speaking, the climate issue is moving from talk to action both in the United States and internationally. While few nations have adopted strict controls or stiff new taxes, a number of them are developing action plans that are making clear their intention to ramp up activity between now and the year 2000... and beyond. There are sensible, economically efficient strategies to be undertaken in the near term that offer the possibility, in many countries, to avoid more draconian measures. These strategies are by-and-large the same measures that the National Academy of Sciences recommended in a 1991 report called, Policy Implications of Greenhouse Warming. The author thinks the Academy`s most important policy contribution was how it recommended the nations act in the face of uncertain science and high risks--that cost effective measures are adopted as cheap insurance... just as nations insure against other high risk, low certainty possibilities, like catastrophic health insurance, auto insurance, and fire insurance. This insurance theme is still right. First, the author addresses how the international climate change negotiations are beginning to produce insurance measures. Next, the author will discuss some of the key issues to watch in those negotiations that relate to longer-term insurance. And finally, the author will report on progress in the United States on the climate insurance plan--The President`s Climate Action Plan.

  16. Stopping and Questioning Suspected Shoplifters Without Creating Civil Liability

    ERIC Educational Resources Information Center

    Reed, Jack R., Jr.

    1977-01-01

    Legal problems concerned with shoplifting suspects are addressed, including common law, criminal penalties, and the merchant's liability. Tangential questions and answers are presented along with discussion of pertinent court cases. (LBH)

  17. Common questions about herpes: analysis of chat-room transcripts.

    PubMed

    Gilbert, Lisa K; Omisore, Folashade

    2009-01-01

    Patients diagnosed with genital herpes typically undergo a period of psychological adjustment. Although healthcare providers can play a key role in this adjustment, in several patient surveys patients have expressed dissatisfaction with the information and counselling offered by professionals. To address this gap, providers must first identify the common questions and myths that are not addressed, or are addressed inadequately. This article is that first step. Through a content analysis of herpes chat-room transcripts captured on their website from autumn 2001 to spring 2006, researchers from the American Social Health Association identified common herpes questions and myths. The 1968 chat passages were coded into 12 themes and 50 sub-themes. Frequently, visitors' questions concerned transmission, symptoms and diagnosis followed by natural history, psychosocial issues and treatment options. The results of this analysis will aid in the creation of tailored messages to address common factual questions and provide psychosocial support.

  18. Opportunities and questions for the fundamental biological sciences in space

    NASA Technical Reports Server (NTRS)

    Sharp, Joseph C.; Vernikos, Joan

    1993-01-01

    With the advent of sophisticated space facilities we discuss the overall nature of some biological questions that can be addressed. We point out the need for broad participation by the biological community, the necessary facilities, and some unique requirements.

  19. Answering Questions and Questioning Answers. Part I. University of Central Florida Conference Papers.

    ERIC Educational Resources Information Center

    Miller, C. C.; And Others

    1982-01-01

    Brief analyses are provided of presentations at a conference, held at the University of Central Florida in Orlando, which addressed questions and answers relating to research and education. Conference sessions explored the role of research in relation to educational practices with special focus on theory, research, issues, and application. Papers…

  20. L'enseignement de la civilisation en questions (Questions on the Teaching of Civilization).

    ERIC Educational Resources Information Center

    Porcher, Louis

    1982-01-01

    The questions addressed concern: (1) the connection between language and culture; (2) the need for a systematic analysis of general methodology in language teaching; and (3) problems related to instructional materials, including content, teaching materials, authentic documents, and the relation between traditional concepts of culture and daily…

  1. Answering Questions and Questioning Answers. Part II. University of Central Florida Conference Papers.

    ERIC Educational Resources Information Center

    Miller, C. C.; And Others

    1982-01-01

    Brief analyses are provided of presentations made at a conference, held at the University of Central Florida in Orlando, which addressed questions and answers relating to research and education. Conference sessions explored the role of research in relation to educational practices with special focus on theory, research, issues and application.…

  2. A Hybrid Approach to Clinical Question Answering

    DTIC Science & Technology

    2014-11-01

    participation in TREC, we submitted a single run using a hybrid Natural Language Processing ( NLP )-driven approach to accomplish the given task. Evaluation re...for the CDS track uses a variety of NLP - based techniques to address the clinical questions provided. We present a description of our approach, and...discuss our experimental setup, results and eval- uation in the subsequent sections. 2 Description of Our Approach Our hybrid NLP -driven method presents a

  3. [Ethical questions in neonatology].

    PubMed

    Popow, C

    1996-01-01

    Rapid scientific progress in the fields of prenatal diagnostics, obstetrics and neonatology has enabled severe malformations and hereditary diseases to be detected at a very early fetal stage and has also led to the survival of very immature newborn infants in increasing numbers. Parents, doctors and nurses must all participate in the difficult decision making with regard to therapeutic alternatives and due respect must be paid to the intersects of the child, the impact on the family, but also to the professional opinion of the attending doctors and carers. Problems of the ethical limits of prenatal diagnostics, as well as the severity of malformations or organ failure justifying termination of pregnancy or intensive care measures are discussed with reference to clinical cases. Likewise, the question of precedence of the rights of the parents and siblings to quality of life versus the right of the infant to live is broached. From the neonatological point of view candid discussion with the parents, painstaking efforts to build up an atmosphere of confidence and the provision of supportive measures on the one hand, whilst avoiding the expression of dogmatic opinions and patronizing attitudes on the other hand, are essential prerequisites in dealing with the ethical dilemmas arising in the pre- and neonatal management of such cases.

  4. Cosmic questions: an introduction.

    PubMed

    Primack, J R; Abrams, N E

    2001-12-01

    This introductory talk at the Cosmic Questions conference sponsored by the AAAS summarizes some earlier pictures of the universe and some pictures based on modern physics and cosmology. The uroboros (snake swallowing its tail) is an example of a traditional picture. The Biblical flat-earth picture was very different from the Greek spherical earth-centered picture, which was the standard view until the end of the Middle Ages. Many people incorrectly assume that the Newtonian picture of stars scattered through otherwise empty space is still the prevailing view. Seeing Earth from space shows the power of a new picture. The Hubble Space Telescope can see all the bright galaxies, all the way to the cosmic Dark Ages. We are at the center of cosmic spheres of time: looking outward is looking backward in time. All the matter and energy in the universe can be represented as a cosmic density pyramid. The laws of physics only allow the material objects in the universe to occupy a wedge-shaped region on a diagram of mass versus size. All sizes--from the smallest size scale, the Planck scale, to the entire visible universe--can be represented on the Cosmic Uroboros. There are interesting connections across this diagram, and the human scale lies in the middle.

  5. Keys to Success: School Facilities Primer, Questions & Answers 101.

    ERIC Educational Resources Information Center

    Brady, Jim

    This publication provides answers to basic questions to help school board members more fully address the complexities of the planning, design, and construction process in order to maximize the goal of student success. The 101 questions and answers are in the areas of: facility planning; learning environment; information technology; safe schools;…

  6. Discriminatory Questions and Applicant Reactions in the Employment Interview.

    ERIC Educational Resources Information Center

    Saks, Alan M.; And Others

    This study investigated the effects of discriminatory interview questions on applicants' perceptions and intentions toward an organization. Participants included 118 graduate business students (59 percent male), average age of 31 with more than eight years of full-time work experience. Discriminatory questions addressed handicaps, plans for…

  7. New Responses to Enduring Questions in Religious and Theological Education

    ERIC Educational Resources Information Center

    Siejk, Cate

    2011-01-01

    This article offers a response to two provocative questions about the relationship of theology to religious education posed by Norma Thompson in her Presidential address given at the annual meeting of APRRE in 1978. I offer contemporary answers to these questions from the perspective of a theological educator. First, I show how feminist theory and…

  8. Early Childhood Teacher Research: From Questions to Results

    ERIC Educational Resources Information Center

    Castle, Kathryn

    2011-01-01

    What is early childhood teacher research and why is it important? How does a teacher researcher formulate a research question and a plan for doing research? How do teachers apply research results to effect change? "Early Childhood Teacher Research" is an exciting new resource that will address the sorts of questions and concerns that pre- and…

  9. Questions and Answers for Reporting for the 2006 Partial Updating of the TSCA Chemical Inventory Database: Inorganic Chemicals Addendum

    EPA Pesticide Factsheets

    This document addresses specific questions related to reporting inorganic chemicals under the IUR and is an addendum to the Questions and Answers for Reporting for the 2006 Partial Updating of the TSCA Chemical Inventory Database (Questions and Answers Document).

  10. Improving the Questions Students Ask

    ERIC Educational Resources Information Center

    Donohue-Smith, Maureen

    2006-01-01

    Teachers often tell their classes that "there is no such thing as a stupid question." But this is not completely honest. Questions aren't asked in a vacuum; their intelligence or stupidity depends on a variety of contextual variables. The ideal question is the right one, posed to the right source in the right way at the right time for the right…

  11. The Hermeneutics of Educational Questioning

    ERIC Educational Resources Information Center

    Bingham, Charles

    2005-01-01

    This article looks at the practice of educational questioning using the philosophical hermeneutics of Hans-Georg Gadamer. It first looks at questions and statements from a hermeneutic perspective, demonstrating some of the differences and similarities between the two. It then details Gadamer's notion of the "true question", asking whether it is…

  12. Does Anyone Have Any Questions?

    ERIC Educational Resources Information Center

    Finkelstein, Judith M.; Ritter, Virginia F.

    The purpose of this study was to determine if answering a child's question with a question produces further analytical questioning by the child. A sample of 80 children in nursery-kindergarten, first, second and third grades (ages ranging from 4-9 years) were divided into two groups. An abstract painting by Kandinsky was shown individually to each…

  13. Children Who Question Their Heterosexuality

    ERIC Educational Resources Information Center

    Carver, Priscilla R.; Egan, Susan K.; Perry, David G.

    2004-01-01

    Many gay, lesbian, and bisexual adults report a period of childhood sexual questioning--an uneasy questioning of their heterosexuality brought on by same-sex attractions and motivating same-sex sexual exploration. This article evaluates hypotheses about the correlates, causes, and consequences of childhood sexual questioning. Participants were 182…

  14. Investigations of Human Question Answering.

    ERIC Educational Resources Information Center

    Graesser, Arthur C.

    The development and testing of QUEST, a model of human question answering, are reported. QUEST accounts for answers adults produce for different categories of open-class questions, identifying the information sources associated with the content words in questions. Each information source is organized in a conceptual graph structure. The model…

  15. The Reach Address Database (RAD)

    EPA Pesticide Factsheets

    The Reach Address Database (RAD) stores reach address information for each Water Program feature that has been linked to the underlying surface water features (streams, lakes, etc) in the National Hydrology Database (NHD) Plus dataset.

  16. Questioning Our Questions: Assessing Question Asking Practices to Evaluate a yPAR Program

    ERIC Educational Resources Information Center

    Grace, Sarah; Langhout, Regina Day

    2014-01-01

    The purpose of this research was to examine question asking practices in a youth participatory action research (yPAR) after school program housed at an elementary school. The research question was: In which ways did the adult question asking practices in a yPAR setting challenge and/or reproduce conventional models of power in educational…

  17. Understanding and addressing health disparities in North Carolina.

    PubMed

    Bell, Ronny A

    2012-01-01

    Health disparities--differences in the provision and outcomes of health care in 2 distinct populations--are pervasive and long-standing in North Carolina. Although some strategies for closing these gaps have been effective, many disparities have resisted attempts to eliminate them. Future efforts should focus on policy implementation and the translation of research findings into effective interventions.

  18. Student Moderators in Asynchronous Online Discussion: A Question of Questions

    ERIC Educational Resources Information Center

    Zingaro, Daniel

    2012-01-01

    Much current research exalts the benefits of having students facilitate weekly discussions in asynchronous online courses. This study seeks to add to what is known about student moderation through an analysis of the types of questions students use to spur each discussion. Prior experimental work has demonstrated that the types of questions posed…

  19. Reference Readiness for AV Questions.

    ERIC Educational Resources Information Center

    Drolet, Leon L., Jr.

    1981-01-01

    Reviews 50 reference tools which librarians can use to answer almost any audiovisual question including queries on trivia, equipment selection, biographical information, and motion picture ratings. (LLS)

  20. CONTENT-ADDRESSABLE MEMORY SYSTEMS,

    DTIC Science & Technology

    The utility of content -addressable memories (CAM’s) within a general purpose computing system is investigated. Word cells within CAM may be...addressed by the character of all or a part of cell contents . Multimembered sets of word cells may be addressed simultaneously. The distributed logical...package is developed which allows simulation of CAM commands within job programs run on the IBM 7090 and derives tallies of execution times corresponding to a particular realization of a CAM system . (Author)

  1. Questioning Questions: Elementary Teachers' Adaptations of Investigation Questions Across the Inquiry Continuum

    NASA Astrophysics Data System (ADS)

    Biggers, Mandy

    2017-01-01

    Questioning is a central practice in science classrooms. However, not every question translates into a "good" science investigation. Questions that drive science investigations can be provided by many sources including the teacher, the curriculum, or the student. The variations in the source of investigation questions were explored in this study. A dataset of 120 elementary science classroom videos and associated lesson plans from 40 elementary teachers (K-5) across 21 elementary school campuses were scored on an instrument measuring the amount of teacher-direction or student-direction of the lessons' investigation questions. Results indicated that the investigation questions were overwhelmingly teacher directed in nature, with no opportunities for students to develop their own questions for investigation. This study has implications for researchers and practitioners alike, calling attention to the teacher-directed nature of investigation questions in existing science curriculum materials, and the need for teacher training in instructional strategies to adapt their existing curriculum materials across the continuum of teacher-directed and student-directed investigation questions. Teachers need strategies for adapting the teacher-directed questions provided in their existing curriculum materials in order to allow students the opportunity to engage in this essential scientific practice.

  2. Introduction: Addressing Air Pollution and Health Science Questions to Inform Science and Policy

    EPA Science Inventory

    This special issue of Air Quality, Atmosphere and Health (AQAH) is the sixth and final in a series of special journal issues (Solomon 2010, 2011a, b; Solomon et al. 2011; Solomon 2012) associated with the 2010 Air Pollution and Heath Conference: Bridging the Gap between Sources ...

  3. Using Dimensional Data to Address Enrollment Management Questions in Higher Education

    ERIC Educational Resources Information Center

    Duniway, Bob; Wiegand, Karl

    2009-01-01

    Enrollment management is central to the success of a college or university. A school must enroll students into courses, completion of a series of which will lead to graduation. While all colleges and universities must manage the enrollment process at least operationally, it is challenging to keep track of all the related data that would allow for…

  4. Methane emissions in the East Siberian Arctic Shelf: issues addressed and questions raised

    NASA Astrophysics Data System (ADS)

    Shakhova, N. E.

    2015-12-01

    Methane (CH4) emissions in the East Siberian Arctic Shelf (ESAS) has been studied during the last decade. Our investigation, including observational studies using hydrological, biogeochemical, geophysical, geo-electrical, microbiological, and isotopic methods, and modeling efforts to assess current subsea permafrost state and the ESAS' contribution to the regional CH4 budget, have clarified processes driving CH4 emissions in the ESAS and spilt some light on possible sources involvement. Despite some authors believe that CH4 fluxes from subsea permafrost in the ESAS will depend on rates of CH4 production in gradually thawing sediments while subsea permafrost will remain frozen for millennia, results of our investigation showed the opposite. Permafrost failure caused by long-lasting warming by sea water due to sea level rise, deep/open taliks formation due to combined heating effects of seawater, river runoff, geothermal flux, and pre-existing thermokarst and global-change-induced warming, determines destabilization of massive gas reservoirs, leading to large-scale CH4 releases, including release of pre-formed CH4 long preserved within/beneath subsea permafrost. Resultant rates of CH4 emissions over the ESAS vary spatially by 3-5 orders of magnitude. Re-drilling of subsea permafrost performed from the fast ice 30 years after it was first drilled in 1982-1983, revealed modern rates of subsea permafrost degradation. These results contradict previous hypotheses that: 1) taliks beneath thermokarst lakes always freeze after submergence; 2) rates of permafrost degradation after inundation decrease over time; and 3) thousands of years required to form escape paths for permafrost-preserved gas. Involvement of shallow relic hydrates is suggested based on results of experimental work with sediment cores extracted from the near-shore zone of the ESAS. In-situ investigations revealed that dissolved CH4 could remain in the seawater up to 1000 days, because oxidation rates are low. Storms could release some aqueous CH4 to atmosphere; dissolved CH4, captured beneath ice in winter, can spread via currents and escape to atmosphere through breaks in the ice. Progressive subsea permafrost thawing and decreasing ice extent could significantly increase CH4 emissions from the ESAS.

  5. Minding Our P's through Q's: Addressing Possibilities and Precautions of Community Work through New Questions

    ERIC Educational Resources Information Center

    Elmendorf, Dana

    2010-01-01

    Art therapists increasingly work outside traditional mental health treatment programs and facilitate art-making experiences within community-based settings. Although traditional mental health facilities provide frameworks for meeting ethical principles such as privacy, roles, consent to treatment, and setting therapeutic goals, community-based art…

  6. Important Questions Remain to Be Addressed before Adopting a Dimensional Classification of Mental Disorders

    ERIC Educational Resources Information Center

    Ruscio, Ayelet Meron

    2008-01-01

    Comments on the original article "Plate tectonics in the classification of personality disorder: Shifting to a dimensional model," by T. A. Widiger and T. J. Trull (2007). Widiger and Trull raised important nosological issues that warrant serious consideration not only for the personality disorders but for all mental disorders as the Diagnostic…

  7. Addressing health inequalities by using Structural Funds. A question of opportunities.

    PubMed

    Neagu, Oana Maria; Michelsen, Kai; Watson, Jonathan; Dowdeswell, Barrie; Brand, Helmut

    2017-03-01

    Making up a third of the EU budget, Structural and Investment Funds can provide important opportunities for investing in policies that tackle inequalities in health. This article looks back and forward at the 2007-2013 and 2014-2020 financial periods in an attempt to inform the development of health equity as a strand of policy intervention under regional development. It combines evidence from health projects funded through Structural Funds and a document analyses that locates interventions for health equity under the new regulations. The map of opportunities has changed considerably since the last programming period, creating more visibility for vulnerable groups, social determinants of health and health systems sustainability. As the current programming period is progressing, this paper contributes to maximizing this potential but also identifying challenges and implementation gaps for prospective health system engagement in pursuing health equity as part of Structural Funds projects. The austerity measures and their impact on public spending, building political support for investments as well as the difficulties around pursuing health gains as an objective of other policy areas are some of the challenges to overcome. European Structural and Investment Funds could be a window of opportunity that triggers engagement for health equity if sectors adopt a transformative approach and overcome barriers, cooperate for common goals and make better use of the availability of these resources.

  8. The most intriguing question in synesthesia research.

    PubMed

    Rouw, Romke; Ridderinkhof, K Richard

    2014-01-01

    This discussion paper forms an insightful addition to the synesthesia literature. Accompanying a steep increase in recent publications on synesthesia, it helps remedy the conspicuous paucity of mechanistic process models explaining the condition. The paper furthermore addresses what is arguably among the most interesting questions: Why do most synesthetes *not* get confused by their additional sensations? This is particularly interesting when phrased in a broader context: What are the mechanisms for deciding which of the sensations we experience reflect something "real" (phenomena in the outside world) and which reflect something that is "not real" (internally generated and private phenomena).

  9. Questioning the Patient, Questioning Hippocrates: Rufus of Ephesus and the Pursuit of Knowledge.

    PubMed

    Letts, Melinda

    2016-01-01

    Rufus of Ephesus' short treatise, Quaestiones Medicinales, the only ancient medical work that takes as its topic the dialogue between doctor and patient, has usually been seen as a procedural practical handbook serving an essentially operational purpose. In this paper I argue that the treatise, with its insistent message that doctors cannot properly understand and treat illnesses unless they supplement their own knowledge by questioning patients, and its remarkable appreciation of the singularity of each patient's experience, shows itself to be no mere handbook but a work addressing the place of questioning in the clinical encounter. I illustrate some of the differences between Rufus' conceptualisation of the relevance and use of questioning and that which can be seen in the theoretical and descriptive writings of Galen and in the Hippocratic corpus, and show how apparent resonances with some of the preoccupations of modern Western healthcare can be used judiciously to elucidate the significance of those differences.

  10. Measuring injury risk factors: question reliability in a statewide sample

    PubMed Central

    Koziol-McLain, J.; Brand, D.; Morgan, D.; Leff, M.; Lowenstein, S.

    2000-01-01

    Background—Recently (1996–98), Colorado added 15 questions pertaining to injury related risks and behaviors to the behavioral risk factor surveillance system (BRFSS). Questions addressed bicycle helmet use, traffic crashes, exposure to violence, suicidal behavior, and gun storage. Objective—To measure the test-retest reliability of these injury related questions. Methods—Of 330 BRFSS participants, 229 (69%) were called a second time and reasked nine selected injury questions. Retests were completed 7–28 days after the original interview. Results—Test-retest agreement was very high (κ >0.80) for bicycle helmet use, domestic police visits, and gun ownership. All other injury risk questions had substantial agreement (κ >0.60). Conclusions—The injury related questions added to the Colorado BRFSS have high test-retest reliability. PMID:10875674

  11. Questions Dog Design of Tests

    ERIC Educational Resources Information Center

    Gewertz, Catherine

    2012-01-01

    On the verge of signing a contract to help design assessments for the common standards, ACT Inc. has withdrawn from the project amid conflict-of-interest questions sparked by its own development of a similar suite of tests. Even though it involves only a small subcontract, the move by the Iowa-based test-maker, and the questions from the state…

  12. Asking Research Questions: Theoretical Presuppositions

    ERIC Educational Resources Information Center

    Tenenberg, Josh

    2014-01-01

    Asking significant research questions is a crucial aspect of building a research foundation in computer science (CS) education. In this article, I argue that the questions that we ask are shaped by internalized theoretical presuppositions about how the social and behavioral worlds operate. And although such presuppositions are essential in making…

  13. Test Pool Questions, Area III.

    ERIC Educational Resources Information Center

    Sloan, Jamee Reid

    This manual contains multiple choice questions to be used in testing students on nurse training objectives. Each test includes several questions covering each concept. The concepts in section A, medical surgical nursing, are diseases of the following systems: musculoskeletal; central nervous; cardiovascular; gastrointestinal; urinary and male…

  14. Toward Automated Consumer Question Answering: Automatically Separating Consumer Questions from Professional Questions in the Healthcare Domain

    PubMed Central

    Liu, Feifan; Antieau, Lamont D.; Yu, Hong

    2011-01-01

    Objective Both healthcare professionals and healthcare consumers have information needs that can be met through the use of computers, specifically via medical question answering systems. However, the information needs of both groups are different in terms of literacy levels and technical expertise, and an effective question answering system must be able to account for these differences if it is to formulate the most relevant responses for users from each group. In this paper, we propose that a first step toward answering the queries of different users is automatically classifying questions according to whether they were asked by healthcare professionals or consumers. Design We obtained two sets of consumer questions (~10,000 questions in total) from Yahoo answers. The professional questions consist of two question collections: 4654 point-of-care questions (denoted as PointCare) obtained from interviews of a group of family doctors following patient visits and 5378 questions from physician practices through professional online services (denoted as OnlinePractice). With more than 20,000 questions combined, we developed supervised machine-learning models for automatic classification between consumer questions and professional questions. To evaluate the robustness of our models, we tested the model that was trained on the Consumer-PointCare dataset on the Consumer-OnlinePractice dataset. We evaluated both linguistic features and statistical features and examined how the characteristics in two different types of professional questions (PointCare vs. OnlinePractice) may affect the classification performance. We explored information gain for feature reduction and the back-off linguistic category features. Results 10-fold cross-validation results showed the best F1-measure of 0.936 and 0.946 on Consumer-PointCare and Consumer-OnlinePractice respectively, and the best F1-measure of 0.891 when testing the Consumer-PointCare model on the Consumer-OnlinePractice dataset

  15. Crohn's disease mistaken for long-standing idiopathic mesenteric panniculitis

    PubMed Central

    Nuzzo, Alexandre; Zappa, Magaly; Cazals-Hatem, Dominique; Bouhnik, Yoram

    2016-01-01

    Abstract Background: Mesenteric panniculitis (MP) is mostly an associated sign of an intra-abdominal or systemic inflammatory primary disease. Nevertheless, etiological and differential diagnosis of idiopathic MP can be challenging when an associate primary cause is not in the foreground. Methods: We report here the case of an isolated small bowel Crohn's disease, long time considered as idiopathic MP. Results: This patient presented to our department with a 10-year history of acute abdominal symptoms evolving with flare-up and remission. A diagnosis of idiopathic MP was made based on compatible CT-scan features along with normal laboratory tests and upper and lower bowel endoscopies. As symptoms recurred, a steroid course was proposed which dramatically improved his condition for years. Finally, an explorative laparoscopy was performed because of concern of malignancy when he returned to our unit with a steroid refractory flare-up and weight loss, along with MP nodes growing up to 10 mm. Crohn's disease was eventually diagnosed, based on histopathological middle-gut bowel resection and numerous granulomas in mesenteric nodes without necrosis. Conclusion: This case emphasizes the importance of excluding inflammatory intestinal lesions before making the diagnosis of idiopathic MP (fecal calprotectin, magnetic resonance enterography, wireless capsule endoscopy). PMID:27684882

  16. Human impact and avulsion: a long-standing relationship

    NASA Astrophysics Data System (ADS)

    Heyvaert, Vanessa M. A.; Walstra, Jan

    2015-04-01

    This study demonstrates that avulsions in Upper and Lower Khuzestan (Iran) are the result of interplay between human-induced and natural causes. The importance of human interference during all stages of river avulsion and the long-term consequences for alluvial fan development is proven. Avulsion can be defined as the diversion of flow from an existing channel onto the floodplain (or the fan surface), eventually resulting in a new channel belt (Allen, 1965). It represents the response of a river system to a wide range of autogenic factors, such as river meandering and vertical accretion, and allogenic controls, such as tectonics, climate change and sea-level change (Jones & Schumm, 1999). The framework used in this study is based on concepts introduced by Slingerland & Smith (2004), regarding avulsion style (i.e. through annexation, progradation or incision), and Makaske (2012), regarding the different phases in the process leading to avulsion (i.e. preconditioning, triggering and post-triggering)on megafans. This study primarily focusses on actions that directly affect river hydraulics, such as the construction and maintenance of dams, embankments, irrigation and diversion canals, the destruction of dams, channel modifications, etc. For several avulsion events, style and controlling factors are examined, and the ways by which human activities have interfered with the natural processes are highlighted. All case-studies are based on an integrated analysis of historical, archaeological, geomorphological and geological datasets. References: Allen, J.R.L., 1965. A review of the origin and characteristics of recent alluvial sediments. Sedimentology, 5, 89-91. Jones, L.S. & Schumm, S.A., 1999. Causes of avulsion: an overview, In: Smith, N.D. & Rogers, J. (Eds.), Fluvial Sedimentology VI, Blackwell Science, Oxford, UK, 171-178. Makaske, B., Maathuis, B.H.P., Padovani, C.R., Stolker, C., Mosselman, E. & Jongman, R.H.G., 2012. Upstream and downstream controls of recent avulsions on the Taquari megafan, Pantanal, south-western Brazil. Earth Surface Processes and Landforms 37, 1313-1326. Slingerland, R. & Smith, N.D., 2004. River avulsions and their deposits. Annual Review of Earth and Planetary Sciences 32, 257-285.

  17. Questioning ORACLE: An Assessment of ORACLE's Analysis of Teachers' Questions and [A Comment on "Questioning ORACLE"].

    ERIC Educational Resources Information Center

    Scarth, John; And Others

    1986-01-01

    Analysis of teachers' questions, part of the ORACLE (Observation Research and Classroom Learning Evaluation) project research, is examined in detail. Scarth and Hammersley argue that the rules ORACLE uses for identifying different types of questions involve levels of ambiguity and inference that threaten reliability and validity of the study's…

  18. Hypothetical constructs, hypothetical questions, and the expert witness.

    PubMed

    Brodsky, Stanley L; Titcomb, Caroline; Sams, David M; Dickson, Kara; Benda, Yves

    2012-01-01

    Professor John Henry Wigmore in 1940 described the hypothetical question as an intolerable obstruction of truth. Since that time, the nature and application of the hypothetical question in the courtroom, as well as responses to this line of questioning during expert testimony, have been sources of controversy. Governed by legal philosophical foundations, the hypothetical construct addresses what there is, in a general sense, and what can or ought to be. Alexy (2004) has described the nature of legal philosophy as the epistemological question of what we can know. This article begins by examining the philosophical underpinnings, legal parameters, and teaching purposes of posing hypothetical queries. A social-psychological backdrop for the use of hypothetical questions is then discussed followed by a broader discussion of the hypothetical question's role in court procedures. This paper identifies hypothetical questions used in court as devices to elicit information, or as predictions that potentially change underlying factual interpretations of evidence. In particular, on cross examination hypothetical questions seek to make opposing experts assume facts that are incongruent with their conclusions or opinions. Sometimes in these situations, experts are led to re-evaluate opinions based on alternative understandings of events and behaviors. Thus, this paper's final aim is to explore a foundational understanding of hypothetical questions asked of expert witnesses with special reference to mental health issues. Options for responding to hypothetical questions on the stand are considered along the dimensions of assertiveness-passivity, compliance-resistance, and possible redefinitions of the hypothetical issues.

  19. Goldfinger: a framework for resolving affect using ideomotor questioning.

    PubMed

    Walsh, B J

    1997-07-01

    The author presents a structured protocol for resolving repressed, suppressed or otherwise dated affect using ideomotor questioning. Essential to this model is a progressive ratification series which addresses affect, cognition and behavior. A questioning tree illustrates the method of affect inquiry and case examples demonstrate its application. This non-invasive, brief procedure is a useful adjunct to other treatment modalities and instrumental in clarifying the focus of treatment.

  20. Questions About Venus after Venus Express

    NASA Astrophysics Data System (ADS)

    Limaye, Sanjay

    2016-04-01

    asymmetry in the haze distribution? (vi) what is the direction of the near surface wind at different locations on the planet? JAXA's Akatsuki orbiter will soon begin collecting unique and valuable observations in April 2016 which will increase our knowledge, but other measurements required to answer these questions require careful and sustained observations within the atmosphere and from surface based stations. Some of these measurements should and can be made by large missions such as Venera-D, Venus Climate Mission or the Venus Flagship Design Reference Mission which have been studied in recent years, but some have not been addressed in such studies. Many new missions to Venus are being developed or conceived and it is important to keep the key questions about Venus in focus.

  1. Climate Leadership Awards Frequent Questions

    EPA Pesticide Factsheets

    Provides answers to frequently asked questions regarding the Climate Leadership Awards, sponsored by EPA's Center for Corporate Climate Leadership with co-sponsorship from the Center for Climate and Energy Solutions and The Climate Registry.

  2. Interview Questions with Bentham Scientific

    NASA Technical Reports Server (NTRS)

    Mather, John C.

    2013-01-01

    John Mather answers questions for an interview for the Bentham Science Newsletter. He covers topics ranging from his childhood, his professional career and his thoughts on research, technology and today's scientists and engineers.

  3. Frequent Questions about TSCA CBI

    EPA Pesticide Factsheets

    General Questions and Answers Concerning Confidential Business Information (CBI) Provisions of the Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act

  4. Solar physics: Dynamo theory questioned

    NASA Astrophysics Data System (ADS)

    Charbonneau, Paul

    2016-07-01

    Observations of X-ray emission -- a diagnostic tool for the mechanisms driving stellar magnetic fields -- from four cool stars call into question accepted models of magnetic-field generation in the Sun and stars. See Letter p.526

  5. Birds: Old Questions and New.

    ERIC Educational Resources Information Center

    Flannery, Maura C.

    2002-01-01

    Discusses questions such as how birds fly and the meaning of bird songs. Explains the relationship between birds and ecological activism and points out the excitement in research and observation of birds. (Contains 34 references.) (YDS)

  6. Resource Classification for Medical Questions

    PubMed Central

    Roberts, Kirk; Rodriguez, Laritza; Shooshan, Sonya E.; Demner-Fushman, Dina

    2016-01-01

    We present an approach for manually and automatically classifying the resource type of medical questions. Three types of resources are considered: patient-specific, general knowledge, and research. Using this approach, an automatic question answering system could select the best type of resource from which to consider answers. We first describe our methodology for manually annotating resource type on four different question corpora totaling over 5,000 questions. We then describe our approach for automatically identifying the appropriate type of resource. A supervised machine learning approach is used with lexical, syntactic, semantic, and topic-based feature types. This approach is able to achieve accuracies in the range of 80.9% to 92.8% across four datasets. Finally, we discuss the difficulties encountered in both manual and automatic classification of this challenging task. PMID:28269901

  7. Frequent Questions About Universal Waste

    EPA Pesticide Factsheets

    Frequent questions such as Who is affected by the universal waste regulations? What is “mercury-containing equipment”? How are waste batteries managed under universal waste? How are waste pesticides managed under universal waste?

  8. Resource Classification for Medical Questions.

    PubMed

    Roberts, Kirk; Rodriguez, Laritza; Shooshan, Sonya E; Demner-Fushman, Dina

    2016-01-01

    We present an approach for manually and automatically classifying the resource type of medical questions. Three types of resources are considered: patient-specific, general knowledge, and research. Using this approach, an automatic question answering system could select the best type of resource from which to consider answers. We first describe our methodology for manually annotating resource type on four different question corpora totaling over 5,000 questions. We then describe our approach for automatically identifying the appropriate type of resource. A supervised machine learning approach is used with lexical, syntactic, semantic, and topic-based feature types. This approach is able to achieve accuracies in the range of 80.9% to 92.8% across four datasets. Finally, we discuss the difficulties encountered in both manual and automatic classification of this challenging task.

  9. Extraction of Questions Behind Messages

    NASA Astrophysics Data System (ADS)

    Matsumura, Naohiro; Kawahara, Daisuke; Okamoto, Masashi; Kurohashi, Sadao; Nishida, Toyoaki

    To overcome the limitation of conventional text-mining approaches in which frequent patterns of word occurrences are to be extracted to understand obvious user needs, this paper proposes an approach to extracting questions behind messages to understand potential user needs. We first extract characteristic case frames by comparing the case frames constructed from target messages with the ones from 25M sentences in the Web and 20M sentences in newspaper articles of 20 years. Then we extract questions behind messages by transforming the characteristic case frames into interrogative sentences based on new information and old information, i.e., replacing new information with WH-question words. The proposed approach is, in other words, a kind of classification of word occurrence pattern. Qualitative evaluations of our preliminary experiments suggest that extracted questions show problem consciousness and alternative solutions -- all of which help to understand potential user needs.

  10. Questions Students Ask: Beta Decay.

    ERIC Educational Resources Information Center

    Koss, Jordan; Hartt, Kenneth

    1988-01-01

    Answers a student's question about the emission of a positron from a nucleus. Discusses the problem from the aspects of the uncertainty principle, beta decay, the Fermi Theory, and modern physics. (YP)

  11. Folic Acid Questions and Answers

    MedlinePlus

    ... Controls NCBDDD Cancel Submit Search The CDC Folic Acid Note: Javascript is disabled or is not supported ... please visit this page: About CDC.gov . Folic Acid Homepage Facts Quiz Frequently Asked Questions General Information ...

  12. Address tracing for parallel machines

    NASA Technical Reports Server (NTRS)

    Stunkel, Craig B.; Janssens, Bob; Fuchs, W. Kent

    1991-01-01

    Recently implemented parallel system address-tracing methods based on several metrics are surveyed. The issues specific to collection of traces for both shared and distributed memory parallel computers are highlighted. Five general categories of address-trace collection methods are examined: hardware-captured, interrupt-based, simulation-based, altered microcode-based, and instrumented program-based traces. The problems unique to shared memory and distributed memory multiprocessors are examined separately.

  13. Records--The Achilles' Heel of School Nursing: Answers to Bothersome Questions

    ERIC Educational Resources Information Center

    Schwab, Nadine C.; Pohlman, Katherine J.

    2004-01-01

    This article addresses practice issues related to school health records and school nursing documentation. Because the issues have been posed by practicing school nurses, the article is in Question and Answer (Q&A) format. Specifically, the questions addressed concern the following: ownership and storage location of student health records when…

  14. Identity crisis of Th17 cells: many forms, many functions, many questions.

    PubMed

    Sundrud, Mark S; Trivigno, Catherine

    2013-11-15

    Th17 cells are a subset of CD4(+) effector T cells characterized by expression of the IL-17-family cytokines, IL-17A and IL-17F. Since their discovery nearly a decade ago, Th17 cells have been implicated in the regulation of dozens of immune-mediated inflammatory diseases and cancer. However, attempts to clarify the development and function of Th17 cells in human health and disease have generated as many questions as answers. On one hand, cytokine expression in Th17 cells appears to be remarkably dynamic and is subject to extensive regulation (both positive and negative) in tissue microenvironments. On the other hand, accumulating evidence suggests that the human Th17 subset is a heterogeneous population composed of several distinct pro- and anti-inflammatory subsets. Clearly, Th17 cells as originally conceived no longer neatly fit the long-standing paradigm of stable and irrepressible effector T cell function. Here we review current concepts surrounding human Th17 cells, with an emphasis on their plasticity, heterogeneity, and their many, tissue-specific functions. In spite of the challenges ahead, a comprehensive understanding of Th17 cells and their relationship to human disease is key to ongoing efforts to develop safer and more selective anti-inflammatory medicines.

  15. Addressing Common Student Errors with Classroom Voting in Multivariable Calculus

    ERIC Educational Resources Information Center

    Cline, Kelly; Parker, Mark; Zullo, Holly; Stewart, Ann

    2012-01-01

    One technique for identifying and addressing common student errors is the method of classroom voting, in which the instructor presents a multiple-choice question to the class, and after a few minutes for consideration and small group discussion, each student votes on the correct answer, often using a hand-held electronic clicker. If a large number…

  16. Working with Second Language Learners: Answers to Teachers' Top Ten Questions.

    ERIC Educational Resources Information Center

    Cary, Stephen

    This book aims to provide practical, research-informed answers to the questions most frequently asked by teachers of second language learners. Every question targets one of the key instructional issues teachers must address to ensure success for their second language students. Included among the questions are: How do I assess a student's English?…

  17. Frequent Questions about Section 508

    EPA Pesticide Factsheets

    Reasonable Accommodation addresses the individual's needs in the workplace, while the Rehabilitation Act Section 508 requires accessibility for all people to electronic and information technology (EIT) equipment and tools to access information or work.

  18. Every Other Day. Keynote Address.

    ERIC Educational Resources Information Center

    Tiller, Tom

    Schools need to be reoriented and restructured so that what is taught and learned, and the way in which it is taught and learned, are better integrated with young people's real-world experiences. Many indicators suggest that the meaningful aspects of school have been lost in the encounter with modern times. The title of this address--"Every…

  19. Agenda to address climate change

    SciTech Connect

    1998-10-01

    This document looks at addressing climate change in the 21st century. Topics covered are: Responding to climate change; exploring new avenues in energy efficiency; energy efficiency and alternative energy; residential sector; commercial sector; industrial sector; transportation sector; communities; renewable energy; understanding forests to mitigate and adapt to climate change; the Forest Carbon budget; mitigation and adaptation.

  20. State of the Lab Address

    ScienceCinema

    King, Alex

    2016-07-12

    In his third-annual State of the Lab address, Ames Laboratory Director Alex King called the past year one of "quiet but strong progress" and called for Ames Laboratory to continue to build on its strengths while responding to changing expectations for energy research.

  1. Research strategies for addressing uncertainties

    USGS Publications Warehouse

    Busch, David E.; Brekke, Levi D.; Averyt, Kristen; Jardine, Angela; Welling, Leigh; Garfin, Gregg; Jardine, Angela; Merideth, Robert; Black, Mary; LeRoy, Sarah

    2013-01-01

    Research Strategies for Addressing Uncertainties builds on descriptions of research needs presented elsewhere in the book; describes current research efforts and the challenges and opportunities to reduce the uncertainties of climate change; explores ways to improve the understanding of changes in climate and hydrology; and emphasizes the use of research to inform decision making.

  2. Gay, Lesbian, Bisexual, Transgender and Questioning Youth Matter!

    ERIC Educational Resources Information Center

    King, Kathleen A.

    2009-01-01

    This brief presents general trends in the social and emotional well-being of youth who identify as Gay, Lesbian, Bisexual, Transgender, and Questioning (GLBTQ), followed by a guide of sexual orientation definitions. Additionally, readers learn a series of steps that schools must address in order to build inclusive, safe, and effective schools for…

  3. Substance Abuse among Gay, Lesbian, Bisexual, Transgender, and Questioning Adolescents.

    ERIC Educational Resources Information Center

    Jordan, Karen M.

    2000-01-01

    Studies indicate that substance abuse is a growing problem among gay, lesbian, bisexual, transgender, and questioning youth. Prevention and intervention efforts can be successful in working with sexual minority adolescents in jeopardy of developing substance abuse problems. School psychologists are uniquely poised to address this problem through…

  4. Perfusion MRI: The Five Most Frequently Asked Clinical Questions

    PubMed Central

    Essig, Marco; Nguyen, Thanh Binh; Shiroishi, Mark S.; Saake, Marc; Provenzale, James M.; Enterline, David S.; Anzalone, Nicoletta; Dörfler, Arnd; Rovira, Àlex; Wintermark, Max; Law, Meng

    2013-01-01

    OBJECTIVE This article addresses questions that radiologists frequently ask when planning, performing, processing, and interpreting MRI perfusion studies in CNS imaging. CONCLUSION Perfusion MRI is a promising tool in assessing stroke, brain tumors, and neurodegenerative diseases. Most of the impediments that have limited the use of perfusion MRI can be overcome to allow integration of these methods into modern neuroimaging protocols. PMID:23971482

  5. Questions for the Study and Teaching of Shakespeare and Milton.

    ERIC Educational Resources Information Center

    DeVito, Angela, Ed.; Medine, Peter, Ed.

    The discussion questions and essay prompts in this collection were compiled from contributions made by participants in the 1991 Arizona Shakespeare-Milton Institute. After an introduction which presents some general guidelines for teachers and students, the collection addresses the following works: "As You Like It"; "The…

  6. Theorizing the Entrepreneurial University: Open Questions and Possible Answers

    ERIC Educational Resources Information Center

    Sotiris, Panagiotis

    2012-01-01

    This article attempts to address theoretical questions regarding the transition towards an entrepreneurial university and the changes associated with this process, namely the increased commodification, the competitive quest for private funding and the introduction of business management practices. The important theoretical advances made in the…

  7. Naptime Tips: Answers to Caregivers Most Frequent Questions.

    ERIC Educational Resources Information Center

    Texas Child Care, 1996

    1996-01-01

    Asserts that children vary in the amount of sleep they need but that rest is important. Gives advice in response to caregiver questions concerning child naptime, including determining length of nap, getting children settled, providing a conducive classroom environment, dealing with resistance, and addressing parental concerns. (BGC)

  8. Validating Two Questions in the Force Concept Inventory with Subquestions

    ERIC Educational Resources Information Center

    Yasuda, Jun-ichiro; Taniguchi, Masa-aki

    2013-01-01

    In this study, we evaluate the structural validity of Q.16 and Q.7 in the Force Concept Inventory (FCI). We address whether respondents who answer Q.16 and Q.7 correctly actually have an understanding of the concepts of physics tested in the questions. To examine respondents' levels of understanding, we use subquestions that test them on concepts…

  9. The Task-Based Approach: Some Questions and Suggestions

    ERIC Educational Resources Information Center

    Littlewood, William

    2004-01-01

    This article first addresses the question of what tasks are. It suggests that rather than accept the common "communicative" definition, we should return to a broader definition and then focus on key dimensions that distinguish (from the learner's perspective) different types of task, notably degrees of task involvement and degrees of focus on form…

  10. Questions of Matter: Critical Conversations in Online Spaces

    ERIC Educational Resources Information Center

    Albers, Peggy; Turnbull, Sarah; Angay-Crowder, Tuba

    2015-01-01

    How professional development is delivered in today's networked world has shifted greatly, and research into online spaces of learning is growing. Numerous questions, however, remain regarding how online spaces can be leveraged to foster meaningful conversations that address current critical educational issues. This qualitative study examines the…

  11. Explaining Errors in Children's Questions

    ERIC Educational Resources Information Center

    Rowland, Caroline F.

    2007-01-01

    The ability to explain the occurrence of errors in children's speech is an essential component of successful theories of language acquisition. The present study tested some generativist and constructivist predictions about error on the questions produced by ten English-learning children between 2 and 5 years of age. The analyses demonstrated that,…

  12. Teaching Ideas: Building Questioning Skills.

    ERIC Educational Resources Information Center

    Felton, Randall G.; Allen, Rodney F.

    1986-01-01

    This exercise shows how to turn the expository treatment of a topic or event into a mystery or puzzling situation that students are asked to solve. Once a puzzle is presented, students may pose only questions that can be answered yes or no. Three sample lessons are included to illustrate the process. (JDH)

  13. Four Questions to Ask Yourself

    ERIC Educational Resources Information Center

    Abilock, Debbie, Ed.

    2007-01-01

    One's commitment to intellectual freedom is manifested not just in the creation of a strong and clear selection policy or the celebration of Banned Books Week but by his or her willingness to examine his or her practices openly with others. In this article, the author proposes four questions to explore in one's teaching and in professional…

  14. Instance-Based Question Answering

    DTIC Science & Technology

    2006-12-01

    answer clustering, composition, and scoring. Moreover, with the effort dedicated to improving monolingual system performance, system parameters are...text collections: document type, manual or automatic annotations (if any), and stylistic and notational differences in technical terms. Monolingual ...forum in which cross language retrieval systems and question answering systems are tested for various Eu- ropean languages. The CLEF QA monolingual task

  15. Constructivism and Objectivism: Additional Questions

    ERIC Educational Resources Information Center

    Meltzer, Edmund S.

    2006-01-01

    In past issues of "The Educational Forum," David Elkind (2004; 2005) and Jamin Carson (2005) have engaged in a dialogue about constructivism and objectivism as viable philosophies of education. In this issue, yet another author joins in the discussion by questioning the role of science and religion in objectivism.

  16. Questionable Methods in Alcoholism Research.

    ERIC Educational Resources Information Center

    Koocher, Gerald P.

    1991-01-01

    Alcoholism research paradigms that use substantial cash incentives to attract participants and that call for alcoholics to consume ethanol in laboratory raise ethical questions. When using such methods, investigators should be obligated to discuss risk-benefit rationales and detail precautionary behaviors to protect participants. Discussion of…

  17. What Children Learn from Questioning

    ERIC Educational Resources Information Center

    Harris, Paul

    2015-01-01

    Research shows that young children ask a multitude of why and how questions. And when they do, they're not simply trying to get adult attention; instead, they're actively seeking information. In this article, Paul Harris describes the findings of a number of research analyses based on extensive transcripts of children's natural speech. Some of the…

  18. Eight Questions for Better Lessons

    ERIC Educational Resources Information Center

    Kriegel, Otis

    2016-01-01

    In this article, veteran educator Otis Kriegel provides eight questions that teachers can ask themselves as they create or tweak lesson plans. With practical, straightforward advice, Kriegel suggests that teachers be mindful of who their audience is, how much students already know, and what materials they'll need. He also urges teachers to…

  19. Ten Practical Questions about Branding

    ERIC Educational Resources Information Center

    Moore, Robert M.; Rattenbury, Jeanne

    2004-01-01

    "Marketing" and "branding" were once considered dirty words on campus but faculty, staff, and board members now appreciate the value of getting their message out and managing their reputation. The question is not so much whether to invest, but when, how, and most important, what's the return on investment? A roundtable of accomplished marketing…

  20. The Geography of Virtual Questioning

    ERIC Educational Resources Information Center

    Mon, Lorri; Bishop, Bradley Wade; McClure, Charles R.; McGilvray, Jessica; Most, Linda; Milas, Theodore Patrick; Snead, John T.

    2009-01-01

    This article explores the geography of virtual questioning by using geographic information systems to study activity within the Florida Electronic Library "Ask a Librarian" collaborative chat service. Researchers mapped participating libraries throughout the state of Florida that served as virtual "entry portals" for users as…

  1. Interpretation of genomic data: questions and answers.

    PubMed

    Simon, Richard

    2008-07-01

    Using a question and answer format we describe important aspects of using genomic technologies in cancer research. The main challenges are not managing the mass of data, but rather the design, analysis, and accurate reporting of studies that result in increased biological knowledge and medical utility. Many analysis issues address the use of expression microarrays but are also applicable to other whole genome assays. Microarray-based clinical investigations have generated both unrealistic hype and excessive skepticism. Genomic technologies are tremendously powerful and will play instrumental roles in elucidating the mechanisms of oncogenesis and in bringing on an era of predictive medicine in which treatments are tailored to individual tumors. Achieving these goals involves challenges in rethinking many paradigms for the conduct of basic and clinical cancer research and for the organization of interdisciplinary collaboration.

  2. [Menstruation in the systemic context. New questions -- questionable connections].

    PubMed

    Lütje, W

    2005-10-01

    Experiencing and the significance of menstruation could possibly be a decisive factor in your physiology or pathologic physiology, in accordance with blood flow disturbance or endometriosis. Menstruation is a systemic, characteristic experience. Evolution, family, culture, community, media, health service and even the economy have an influence on the "period system". Damage and use, sense and the nonsensical of regular bleeding stand to the test. The cycle comes under increasing "pressure" and is no longer in "rhythm". Counter regulation, through regulation of the period seems to prevent the personal, community and health-wise restrictions. The price for this is unknown. Clearly, there is no longer a path between a natural, relaxed acceptance of and an artificial abolition of blood flow. The question of direction is posed in the menarche. This question remains unanswered even in our time.

  3. Does racism harm health? Did child abuse exist before 1962? On explicit questions, critical science, and current controversies: an ecosocial perspective.

    PubMed

    Krieger, Nancy

    2008-09-01

    Research on racism as a harmful determinant of population health is in its infancy. Explicitly naming a long-standing problem long recognized by those affected, this work has the potential to galvanize inquiry and action, much as the 1962 publication of the Kempe et al. scientific article on the "battered child syndrome" dramatically increased attention to-and prompted new research on-the myriad consequences of child abuse, a known yet neglected social phenomenon. To further work on connections between racism and health, the author addresses 3 interrelated issues: (1) links between racism, biology, and health; (2) methodological controversies over how to study the impact of racism on health; and (3) debates over whether racism or class underlies racial/ethnic disparities in health.

  4. Does racism harm health? Did child abuse exist before 1962? On explicit questions, critical science, and current controversies: an ecosocial perspective.

    PubMed

    Krieger, Nancy

    2003-02-01

    Research on racism as a harmful determinant of population health is in its infancy. Explicitly naming a long-standing problem long recognized by those affected, this work has the potential to galvanize inquiry and action, much as the 1962 publication of the Kempe et al. scientific article on the "battered child syndrome" dramatically increased attention to-and prompted new research on-the myriad consequences of child abuse, a known yet neglected social phenomenon. To further work on connections between racism and health, the author addresses 3 interrelated issues: (1) links between racism, biology, and health; (2) methodological controversies over how to study the impact of racism on health; and (3) debates over whether racism or class underlies racial/ethnic disparities in health.

  5. Atomic clusters with addressable complexity

    NASA Astrophysics Data System (ADS)

    Wales, David J.

    2017-02-01

    A general formulation for constructing addressable atomic clusters is introduced, based on one or more reference structures. By modifying the well depths in a given interatomic potential in favour of nearest-neighbour interactions that are defined in the reference(s), the potential energy landscape can be biased to make a particular permutational isomer the global minimum. The magnitude of the bias changes the resulting potential energy landscape systematically, providing a framework to produce clusters that should self-organise efficiently into the target structure. These features are illustrated for small systems, where all the relevant local minima and transition states can be identified, and for the low-energy regions of the landscape for larger clusters. For a 55-particle cluster, it is possible to design a target structure from a transition state of the original potential and to retain this structure in a doubly addressable landscape. Disconnectivity graphs based on local minima that have no direct connections to a lower minimum provide a helpful way to visualise the larger databases. These minima correspond to the termini of monotonic sequences, which always proceed downhill in terms of potential energy, and we identify them as a class of biminimum. Multiple copies of the target cluster are treated by adding a repulsive term between particles with the same address to maintain distinguishable targets upon aggregation. By tuning the magnitude of this term, it is possible to create assemblies of the target cluster corresponding to a variety of structures, including rings and chains.

  6. Conducting systematic reviews of intervention questions I: Writing the review protocol, formulating the question and searching the literature.

    PubMed

    O'Connor, A M; Anderson, K M; Goodell, C K; Sargeant, J M

    2014-06-01

    This article is the fourth of six articles addressing systematic reviews in animal agriculture and veterinary medicine. Previous articles in the series have introduced systematic reviews, discussed study designs and hierarchies of evidence, and provided details on conducting randomized controlled trials, a common design for use in systematic reviews. This article describes development of a review protocol and the first two steps in a systematic review: formulating a review question, and searching the literature for relevant research. The emphasis is on systematic reviews of questions related to interventions. The review protocol is developed prior to conducting the review and specifies the plan for the conduct of the review, identifies the roles and responsibilities of the review team and provides structured definitions related to the review question. For intervention questions, the review question should be defined by the PICO components: population, intervention, comparison and outcome(s). The literature search is designed to identify all potentially relevant original research that may address the question. Search terms related to some or all of the PICO components are entered into literature databases, and searches for unpublished literature also are conducted. All steps of the literature search are documented to provide transparent reporting of the process.

  7. On a question of Gross

    NASA Astrophysics Data System (ADS)

    Banerjee, Abhijit

    2007-03-01

    Using the notion of weighted sharing of sets we prove two uniqueness theorems which improve the results proved by Fang and Qiu [H. Qiu, M. Fang, A unicity theorem for meromorphic functions, Bull. Malaysian Math. Sci. Soc. 25 (2002) 31-38], Lahiri and Banerjee [I. Lahiri, A. Banerjee, Uniqueness of meromorphic functions with deficient poles, Kyungpook Math. J. 44 (2004) 575-584] and Yi and Lin [H.X. Yi, W.C. Lin, Uniqueness theorems concerning a question of Gross, Proc. Japan Acad. Ser. A 80 (2004) 136-140] and thus provide an answer to the question of Gross [F. Gross, Factorization of meromorphic functions and some open problems, in: Proc. Conf. Univ. Kentucky, Lexington, KY, 1976, in: Lecture Notes in Math., vol. 599, Springer, Berlin, 1977, pp. 51-69], under a weaker hypothesis.

  8. Recognizing Young Readers' Spoken Questions

    ERIC Educational Resources Information Center

    Chen, Wei; Mostow, Jack; Aist, Gregory

    2013-01-01

    Free-form spoken input would be the easiest and most natural way for young children to communicate to an intelligent tutoring system. However, achieving such a capability poses a challenge both to instruction design and to automatic speech recognition. To address the difficulties of accepting such input, we adopt the framework of predictable…

  9. Classroom Questions. ERIC/AE Digest.

    ERIC Educational Resources Information Center

    Brualdi, Amy C.

    Questioning is one of the most popular modes of teaching, but it has the capacity to turn a child off to learning if done incorrectly. This digest provides teachers with information on the types of questions and questioning behaviors that can facilitate the learning process and on the types of questions that are ineffective. Good questions foster…

  10. Identifying and Addressing Vaccine Hesitancy

    PubMed Central

    Kestenbaum, Lori A.; Feemster, Kristen A.

    2015-01-01

    In the 20th century, the introduction of multiple vaccines significantly reduced childhood morbidity, mortality, and disease outbreaks. Despite, and perhaps because of, their public health impact, an increasing number of parents and patients are choosing to delay or refuse vaccines. These individuals are described as vaccine hesitant. This phenomenon has developed due to the confluence of multiple social, cultural, political and personal factors. As immunization programs continue to expand, understanding and addressing vaccine hesitancy will be crucial to their successful implementation. This review explores the history of vaccine hesitancy, its causes, and suggested approaches for reducing hesitancy and strengthening vaccine acceptance. PMID:25875982

  11. Identifying and addressing vaccine hesitancy.

    PubMed

    Kestenbaum, Lori A; Feemster, Kristen A

    2015-04-01

    In the 20th century, the introduction of multiple vaccines significantly reduced childhood morbidity, mortality, and disease outbreaks. Despite, and perhaps because of, their public health impact, an increasing number of parents and patients are choosing to delay or refuse vaccines. These individuals are described as "vaccine hesitant." This phenomenon has developed due to the confluence of multiple social, cultural, political, and personal factors. As immunization programs continue to expand, understanding and addressing vaccine hesitancy will be crucial to their successful implementation. This review explores the history of vaccine hesitancy, its causes, and suggested approaches for reducing hesitancy and strengthening vaccine acceptance.

  12. Nanoscale content-addressable memory

    NASA Technical Reports Server (NTRS)

    Davis, Bryan (Inventor); Principe, Jose C. (Inventor); Fortes, Jose (Inventor)

    2009-01-01

    A combined content addressable memory device and memory interface is provided. The combined device and interface includes one or more one molecular wire crossbar memories having spaced-apart key nanowires, spaced-apart value nanowires adjacent to the key nanowires, and configurable switches between the key nanowires and the value nanowires. The combination further includes a key microwire-nanowire grid (key MNG) electrically connected to the spaced-apart key nanowires, and a value microwire-nanowire grid (value MNG) electrically connected to the spaced-apart value nanowires. A key or value MNGs selects multiple nanowires for a given key or value.

  13. Addressing inequities in healthy eating.

    PubMed

    Friel, Sharon; Hattersley, Libby; Ford, Laura; O'Rourke, Kerryn

    2015-09-01

    What, when, where and how much people eat is influenced by a complex mix of factors at societal, community and individual levels. These influences operate both directly through the food system and indirectly through political, economic, social and cultural pathways that cause social stratification and influence the quality of conditions in which people live their lives. These factors are the social determinants of inequities in healthy eating. This paper provides an overview of the current evidence base for addressing these determinants and for the promotion of equity in healthy eating.

  14. Addressing the workforce pipeline challenge

    SciTech Connect

    Leonard Bond; Kevin Kostelnik; Richard Holman

    2006-11-01

    A secure and affordable energy supply is essential for achieving U.S. national security, in continuing U.S. prosperity and in laying the foundations to enable future economic growth. To meet this goal the next generation energy workforce in the U.S., in particular those needed to support instrumentation, controls and advanced operations and maintenance, is a critical element. The workforce is aging and a new workforce pipeline, to support both current generation and new build has yet to be established. The paper reviews the challenges and some actions being taken to address this need.

  15. Interim Exceptional Events Rule Frequently Asked Questions

    EPA Pesticide Factsheets

    Air agencies and other stakeholders have raised technical questions and issues related to implementation since the EPA promulgated the EER. This Question and Answer (Q&A) document is intended to respond to some of these frequently asked questions.

  16. Address the Major Societal Challenges

    NASA Astrophysics Data System (ADS)

    Laubichler, Manfred

    In his famous historical account about the origins of molecular biology Gunther Stent introduced a three phase sequence that turns out to be characteristic for many newly emerging paradigms within science. New ideas, according to Stent, follow a sequence of romantic, dogmatic, and academic phases. One can easily see that complex systems science followed this path. The question now is whether we are in an extended academic phase of gradually expanding both theoretical and practical knowledge, or whether we are entering a new transformation of complex systems science that might well bring about a new romantic phase. I would argue that complexity science, indeed, is at the dawn of a new period - let's call it complexity 3.0. The last academic phase has seen the application of complex systems ideas and methods in a variety of different domains. It has been to a large extent business as usual...

  17. Geomorphic and vegetation processes of the Willamette River floodplain, Oregon: current understanding and unanswered science questions

    USGS Publications Warehouse

    Wallick, J. Rose; Jones, Krista L.; O'Connor, Jim E.; Keith, Mackenzie K.; Hulse, David; Gregory, Stanley V.

    2013-01-01

    4. How is the succession of native floodplain vegetation shaped by present-day flow and sediment conditions? Answering these questions will produce baseline data on the current distributions of landforms and habitats (question 1), the extent of the functional floodplain (question 2), and the effects of modern flow and sediment regimes on future floodplain landforms, habitats, and vegetation succession (questions 3 and 4). Addressing questions 1 and 2 is a logical next step because they underlie questions 3 and 4. Addressing these four questions would better characterize the modern Willamette Basin and help in implementing and setting realistic targets for ongoing management strategies, demonstrating their effectiveness at the site and basin scales, and anticipating future trends and conditions.

  18. Information Extraction Supported Question Answering

    DTIC Science & Technology

    1999-10-15

    cymfony.com, wei@cymfony.com phone : (716) 565-9114 fax: (716) 565-0308 15 October, 1999 Abstract This paper discusses the use of our information...display a currently valid OMB control number . 1. REPORT DATE 19 OCT 1999 2. REPORT TYPE 3. DATES COVERED 00-10-1999 to 00-10-1999 4. TITLE AND...SUBTITLE Information Extraction Supported Question Answering 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

  19. Biology Question Generation from a Semantic Network

    NASA Astrophysics Data System (ADS)

    Zhang, Lishan

    Science instructors need questions for use in exams, homework assignments, class discussions, reviews, and other instructional activities. Textbooks never have enough questions, so instructors must find them from other sources or generate their own questions. In order to supply instructors with biology questions, a semantic network approach was developed for generating open response biology questions. The generated questions were compared to professional authorized questions. To boost students' learning experience, adaptive selection was built on the generated questions. Bayesian Knowledge Tracing was used as embedded assessment of the student's current competence so that a suitable question could be selected based on the student's previous performance. A between-subjects experiment with 42 participants was performed, where half of the participants studied with adaptive selected questions and the rest studied with mal-adaptive order of questions. Both groups significantly improved their test scores, and the participants in adaptive group registered larger learning gains than participants in the control group. To explore the possibility of generating rich instructional feedback for machine-generated questions, a question-paragraph mapping task was identified. Given a set of questions and a list of paragraphs for a textbook, the goal of the task was to map the related paragraphs to each question. An algorithm was developed whose performance was comparable to human annotators. A multiple-choice question with high quality distractors (incorrect answers) can be pedagogically valuable as well as being much easier to grade than open-response questions. Thus, an algorithm was developed to generate good distractors for multiple-choice questions. The machine-generated multiple-choice questions were compared to human-generated questions in terms of three measures: question difficulty, question discrimination and distractor usefulness. By recruiting 200 participants from

  20. No question about exciting questions in cell biology.

    PubMed

    Pollard, Thomas D

    2013-12-01

    Although we have a good grasp of many important processes in cell biology, including knowledge of many molecules involved and how they interact with each other, we still do not understand most of the dynamical features that are the essence of living systems. Fortunately, we now have the ability to dissect biological systems in enough detail to understand their dynamics, including the use of mathematical models to account for past observations and predict future experiments. This deep level of mechanistic understanding should be our goal—not simply to satisfy our scientific curiosity, but also to understand the causes of disease well enough to predict risks, make early diagnoses, and treat effectively. Many big questions remain to be answered before we reach this goal of understanding cellular dynamics.

  1. Content-addressable holographic databases

    NASA Astrophysics Data System (ADS)

    Grawert, Felix; Kobras, Sebastian; Burr, Geoffrey W.; Coufal, Hans J.; Hanssen, Holger; Riedel, Marc; Jefferson, C. Michael; Jurich, Mark C.

    2000-11-01

    Holographic data storage allows the simultaneous search of an entire database by performing multiple optical correlations between stored data pages and a search argument. We have recently developed fuzzy encoding techniques for this fast parallel search and demonstrated a holographic data storage system that searches digital data records with high fidelity. This content-addressable retrieval is based on the ability to take the two-dimensional inner product between the search page and each stored data page. We show that this ability is lost when the correlator is defocussed to avoid material oversaturation, but can be regained by the combination of a random phase mask and beam confinement through total internal reflection. Finally, we propose an architecture in which spatially multiplexed holograms are distributed along the path of the search beam, allowing parallel search of large databases.

  2. Addressing viral resistance through vaccines

    PubMed Central

    Laughlin, Catherine; Schleif, Amanda; Heilman, Carole A

    2015-01-01

    Antimicrobial resistance is a serious healthcare concern affecting millions of people around the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance, but it is important to consider approaches to address this growing issue. While vaccination is a logical strategy, and has been shown to be successful many times over, next generation viral vaccines with a specific goal of curbing antiviral resistance will need to clear several hurdles including vaccine design, evaluation and implementation. This article suggests that a new model of vaccination may need to be considered: rather than focusing on public health, this model would primarily target sectors of the population who are at high risk for complications from certain infections. PMID:26604979

  3. Addressing Failures in Exascale Computing

    SciTech Connect

    Snir, Marc; Wisniewski, Robert; Abraham, Jacob; Adve, Sarita; Bagchi, Saurabh; Balaji, Pavan; Belak, J.; Bose, Pradip; Cappello, Franck; Carlson, Bill; Chien, Andrew; Coteus, Paul; DeBardeleben, Nathan; Diniz, Pedro; Engelmann, Christian; Erez, Mattan; Fazzari, Saverio; Geist, Al; Gupta, Rinku; Johnson, Fred; Krishnamoorthy, Sriram; Leyffer, Sven; Liberty, Dean; Mitra, Subhasish; Munson, Todd; Schreiber, Rob; Stearley, Jon; Van Hensbergen, Eric

    2014-01-01

    We present here a report produced by a workshop on Addressing failures in exascale computing' held in Park City, Utah, 4-11 August 2012. The charter of this workshop was to establish a common taxonomy about resilience across all the levels in a computing system, discuss existing knowledge on resilience across the various hardware and software layers of an exascale system, and build on those results, examining potential solutions from both a hardware and software perspective and focusing on a combined approach. The workshop brought together participants with expertise in applications, system software, and hardware; they came from industry, government, and academia, and their interests ranged from theory to implementation. The combination allowed broad and comprehensive discussions and led to this document, which summarizes and builds on those discussions.

  4. Addressing failures in exascale computing

    SciTech Connect

    Snir, Marc; Wisniewski, Robert W.; Abraham, Jacob A.; Adve, Sarita; Bagchi, Saurabh; Balaji, Pavan; Belak, Jim; Bose, Pradip; Cappello, Franck; Carlson, William; Chien, Andrew A.; Coteus, Paul; Debardeleben, Nathan A.; Diniz, Pedro; Engelmann, Christian; Erez, Mattan; Saverio, Fazzari; Geist, Al; Gupta, Rinku; Johnson, Fred; Krishnamoorthy, Sriram; Leyffer, Sven; Liberty, Dean; Mitra, Subhasish; Munson, Todd; Schreiber, Robert; Stearly, Jon; Van Hensbergen, Eric

    2014-05-01

    We present here a report produced by a workshop on “Addressing Failures in Exascale Computing” held in Park City, Utah, August 4–11, 2012. The charter of this workshop was to establish a common taxonomy about resilience across all the levels in a computing system; discuss existing knowledge on resilience across the various hardware and software layers of an exascale system; and build on those results, examining potential solutions from both a hardware and software perspective and focusing on a combined approach. The workshop brought together participants with expertise in applications, system software, and hardware; they came from industry, government, and academia; and their interests ranged from theory to implementation. The combination allowed broad and comprehensive discussions and led to this document, which summarizes and builds on those discussions.

  5. Light addressable photoelectrochemical cyanide sensor

    SciTech Connect

    Licht, S.; Myung, N.; Sun, Y.

    1996-03-15

    A sensor is demonstrated that is capable of spatial discrimination of cyanide with use of only a single stationary sensing element. Different spatial regions of the sensing element are light activated to reveal the solution cyanide concentration only at the point of illumination. In this light addressable photoelectrochemical (LAP) sensor the sensing element consists of an n-CdSe electrode immersed in solution, with the open-circuit potential determined under illumination. In alkaline ferro-ferri-cyanide solution, the open-circuit photopotential is highly responsive to cyanide, with a linear response of (120 mV) log [KCN]. LAP detection with a spatial resolution of {+-}1 mm for cyanide detection is demonstrated. The response is almost linear for 0.001-0.100 m cyanide with a resolution of 5 mV. 38 refs., 7 figs., 1 tab.

  6. Open questions in classical gravity

    SciTech Connect

    Mannheim, P.D. )

    1994-04-01

    In this work, the authors discuss some outstanding open questions regarding the validity and uniqueness of the standard second-order Newton-Einstein classical gravitational theory. On the observational side the authors discuss the degree to which the realm of validity of Newton's law of gravity can actually be extended to distances much larger than the solar system distance scales on which the law was originally established. On the theoretical side the authors identify some commonly accepted (but actually still open to question) assumptions which go into the formulation of the standard second-order Einstein theory in the first place. In particular, it is shown that while the familiar second-order Poisson gravitational equation (and accordingly its second-order covariant Einstein generalization) may be sufficient to yield Newton's law of gravity they are not in fact necessary. The standard theory thus still awaits the identification of some principle which would then make it necessary too. It is shown that current observational information does not exclusively mandate the standard theory, and that the conformal invariant fourth-order theory of gravity considered recently by Mannheim and Kazanas is also able to meet the constraints of data, and in fact to do so without the need for any so far unobserved nonluminous or dark matter. 37 refs., 7 figs.

  7. Addressing health literacy in patient decision aids

    PubMed Central

    2013-01-01

    Background Effective use of a patient decision aid (PtDA) can be affected by the user’s health literacy and the PtDA’s characteristics. Systematic reviews of the relevant literature can guide PtDA developers to attend to the health literacy needs of patients. The reviews reported here aimed to assess: 1. a) the effects of health literacy / numeracy on selected decision-making outcomes, and b) the effects of interventions designed to mitigate the influence of lower health literacy on decision-making outcomes, and 2. the extent to which existing PtDAs a) account for health literacy, and b) are tested in lower health literacy populations. Methods We reviewed literature for evidence relevant to these two aims. When high-quality systematic reviews existed, we summarized their evidence. When reviews were unavailable, we conducted our own systematic reviews. Results Aim 1: In an existing systematic review of PtDA trials, lower health literacy was associated with lower patient health knowledge (14 of 16 eligible studies). Fourteen studies reported practical design strategies to improve knowledge for lower health literacy patients. In our own systematic review, no studies reported on values clarity per se, but in 2 lower health literacy was related to higher decisional uncertainty and regret. Lower health literacy was associated with less desire for involvement in 3 studies, less question-asking in 2, and less patient-centered communication in 4 studies; its effects on other measures of patient involvement were mixed. Only one study assessed the effects of a health literacy intervention on outcomes; it showed that using video to improve the salience of health states reduced decisional uncertainty. Aim 2: In our review of 97 trials, only 3 PtDAs overtly addressed the needs of lower health literacy users. In 90% of trials, user health literacy and readability of the PtDA were not reported. However, increases in knowledge and informed choice were reported in those studies

  8. Addressing Underrepresentation: Physics Teaching for All

    NASA Astrophysics Data System (ADS)

    Rifkin, Moses

    2016-02-01

    Every physics teacher wants to give his or her students the opportunity to learn physics well. Despite these intentions, certain groups of students—including women and underrepresented minorities (URMs)—are not taking and not remaining in physics. In many cases, these disturbing trends are more significant in physics than in any other science. This is a missed opportunity for our discipline because demographic diversity strengthens science. The question is what we can do about these trends in our classrooms, as very few physics teachers have been explicitly prepared to address them. In this article, I will share some steps that I've taken in my classroom that have moved my class in the right direction. In the words of Nobel Prize-winning physicist Carl Wieman and psychologists Lauren Aguilar and Gregory Walton: "By investing a small amount of class time in carefully designed and implemented interventions, physics teachers can promote greater success among students from diverse backgrounds. Ultimately, we hope such efforts will indeed improve the diversity and health of the physics profession."

  9. [Nursing] Test Pool Questions. Area II.

    ERIC Educational Resources Information Center

    Watkins, Nettie; Patton, Bob

    This manual consists of area 2 test pool questions which are designed to assist instructors in selecting appropriate questions to help prepare practical nursing students for the Oklahoma state board exam. Multiple choice questions are utilized to facilitate testing of nursing 2 curriculum objectives. Each test contains questions covering each…

  10. Five Strategies for Questioning with Intention

    ERIC Educational Resources Information Center

    Costa, Arthur L.; Kallick, Bena

    2015-01-01

    Masterful teachers don't just ask a lot of questions; they ask questions in a purposeful way. In this article, Costa and Kallick describe five strategies that can help teachers become more purposeful in designing and posing questions. One strategy is to plan questions that elicit student thinking at various cognitive levels, from simple recall of…

  11. Socrates' questions: a focus for nursing.

    PubMed

    Bunkers, Sandra S

    2004-07-01

    This column focuses on the philosophical dialogue originated by Socrates. Six questions that Socrates would ask the ancient Greeks are explored in discussing a book written by Phillips entitled Six Questions of Socrates. These questions were: What is virtue? What is moderation? What is justice? What is good? What is courage? What is piety? A human becoming perspective is used as a lens to view the discussion on these questions and the question is posed, "What would it be like to frame discussions on health and quality of life around Socrates' questions?" Parse's teaching-learning processes are presented as a means of creating an environment where dialogue on these questions can occur.

  12. A region addresses patient safety.

    PubMed

    Feinstein, Karen Wolk; Grunden, Naida; Harrison, Edward I

    2002-06-01

    The Pittsburgh Regional Healthcare Initiative (PRHI) is a coalition of 35 hospitals, 4 major insurers, more than 30 major and small-business health care purchasers, dozens of corporate and civic leaders, organized labor, and partnerships with state and federal government all working together to deliver perfect patient care throughout Southwestern Pennsylvania. PRHI believes that in pursuing perfection, many of the challenges facing today's health care delivery system (eg, waste and error in the delivery of care, rising costs, frustration and shortage among clinicians and workers, financial distress, overcapacity, and lack of access to care) will be addressed. PRHI has identified patient safety (nosocomial infections and medication errors) and 5 clinical areas (obstetrics, orthopedic surgery, cardiac surgery, depression, and diabetes) as ideal starting points. In each of these areas of work, PRHI partners have assembled multifacility/multidisciplinary groups charged with defining perfection, establishing region-wide reporting systems, and devising and implementing recommended improvement strategies and interventions. Many design and conceptual elements of the PRHI strategy are adapted from the Toyota Production System and its Pittsburgh derivative, the Alcoa Business System. PRHI is in the proof-of-concept phase of development.

  13. Frequently Asked Questions from EPA's Community Air Monitoring Training Event, July 2015

    EPA Pesticide Factsheets

    EPA's Community Air Monitoring Training Event on July 9, 2015 in RTP, NC. Forty citizen scientists attended in person while over 500 others attended the live webinar. Several attendees posted questions, which EPA scientists have addressed here.

  14. The Hyperloop as a Source of Interesting Estimation Questions

    NASA Astrophysics Data System (ADS)

    Allain, Rhett

    2014-03-01

    The Hyperloop is a conceptual high speed transportation system proposed by Elon Musk. The basic idea uses passenger capsules inside a reduced pressure tube. Even though the actual physics of dynamic air flow in a confined space can be complicated, there are a multitude estimation problems that can be addressed. These back-of-the-envelope questions can be approximated by physicists of all levels as well as the general public and serve as a great example of the fundamental aspects of physics.

  15. Perfusion MRI: The Five Most Frequently Asked Technical Questions

    PubMed Central

    Essig, Marco; Shiroishi, Mark S.; Nguyen, Thanh Binh; Saake, Marc; Provenzale, James M.; Enterline, David; Anzalone, Nicoletta; Dörfler, Arnd; Rovira, Àlex; Wintermark, Max; Law, Meng

    2013-01-01

    OBJECTIVE This and its companion article address the 10 most frequently asked questions that radiologists face when planning, performing, processing, and interpreting different MR perfusion studies in CNS imaging. CONCLUSION Perfusion MRI is a promising tool in assessing stroke, brain tumors, and patients with neurodegenerative diseases. Most of the impediments that have limited the use of perfusion MRI can be overcome to allow integration of these methods into modern neuroimaging protocols. PMID:23255738

  16. Grids: The Top Ten Questions

    DOE PAGES

    Schopf, Jennifer M.; Nitzberg, Bill

    2002-01-01

    The design and implementation of a national computing system and data grid has become a reachable goal from both the computer science and computational science point of view. A distributed infrastructure capable of sophisticated computational functions can bring many benefits to scientific work, but poses many challenges, both technical and socio-political. Technical challenges include having basic software tools, higher-level services, functioning and pervasive security, and standards, while socio-political issues include building a user community, adding incentives for sites to be part of a user-centric environment, and educating funding sources about the needs of this community. This paper details the areasmore » relating to Grid research that we feel still need to be addressed to fully leverage the advantages of the Grid.« less

  17. Core questions in domestication research

    PubMed Central

    Zeder, Melinda A.

    2015-01-01

    The domestication of plants and animals is a key transition in human history, and its profound and continuing impacts are the focus of a broad range of transdisciplinary research spanning the physical, biological, and social sciences. Three central aspects of domestication that cut across and unify this diverse array of research perspectives are addressed here. Domestication is defined as a distinctive coevolutionary, mutualistic relationship between domesticator and domesticate and distinguished from related but ultimately different processes of resource management and agriculture. The relative utility of genetic, phenotypic, plastic, and contextual markers of evolving domesticatory relationships is discussed. Causal factors are considered, and two leading explanatory frameworks for initial domestication of plants and animals, one grounded in optimal foraging theory and the other in niche-construction theory, are compared. PMID:25713127

  18. Discussing the diagnosis of HPV-OSCC: common questions and answers

    PubMed Central

    Fakhry, Carole; D’Souza, Gypsyamber

    2014-01-01

    Human papillomavirus (HPV) is responsible for a rising proportion of oropharyngeal squamous cell cancers (OSCC). HPV-positive OSCCs (HPV-OSCC) are associated with oral HPV infection and sexual behavior. Patient questions regarding risk factors, prognosis and implications for past, present and future relationships often arise. This manuscript addresses frequently asked questions by patients with HPV-OSCC and their families. A framework for clinicians to address these conversations and the limitations of our present knowledge base is also presented. PMID:23876627

  19. Evaluation of four maternal smoking questions.

    PubMed Central

    Kharrazi, M; Epstein, D; Hopkins, B; Kreutzer, R; Doebbert, G; Hiatt, R; Swan, S; Eskenazi, B; Pirkle, J L; Bernert, J T

    1999-01-01

    OBJECTIVE: The authors evaluated four questions about maternal smoking during pregnancy for use on birth certificates. METHODS: Question 1 (yes/no format) and Question 2 (trimester-specific design) were tested among 1171 women who delivered at two Kaiser Permanente medical centers in northern California. Responses to Questions 1 and 2 were compared with smoking information provided by participants in telephone interviews conducted during pregnancy. Question 3 (multiple choice format) and Question 4 (month- and grouped month-specific design) were tested among 900 women who enrolled in a statewide prenatal screening program and who delivered in 20 hospitals in four Central Valley counties. Responses to Questions 3 and 4 were compared with mid-pregnancy serum cotinine levels. The authors evaluated the four questions in terms of conciseness, response rate, data accuracy, and type of data requested. RESULTS: Questions 1 and 2 were the most concise. Response rates could not be calculated for Questions 1 and 2. Response rates were 86.0% for Question 3 and 74.2% for Question 4. Sensitivity was 47.3% for Question 1, 62.1% for Question 2, 83.8% for Question 3, and 86.7% for Question 4. The types of data requested by Questions 2 and 4 seem to best satisfy the needs of the broad audience of birth certificate users. CONCLUSIONS: No single question was clearly superior. The authors propose a combination of Questions 2 and 4, which asks about average number of cigarettes smoked per day in the three months before pregnancy and in each trimester of pregnancy. PMID:9925173

  20. Drug discovery FAQs: workflows for answering multidomain drug discovery questions.

    PubMed

    Chichester, Christine; Digles, Daniela; Siebes, Ronald; Loizou, Antonis; Groth, Paul; Harland, Lee

    2015-04-01

    Modern data-driven drug discovery requires integrated resources to support decision-making and enable new discoveries. The Open PHACTS Discovery Platform (http://dev.openphacts.org) was built to address this requirement by focusing on drug discovery questions that are of high priority to the pharmaceutical industry. Although complex, most of these frequently asked questions (FAQs) revolve around the combination of data concerning compounds, targets, pathways and diseases. Computational drug discovery using workflow tools and the integrated resources of Open PHACTS can deliver answers to most of these questions. Here, we report on a selection of workflows used for solving these use cases and discuss some of the research challenges. The workflows are accessible online from myExperiment (http://www.myexperiment.org) and are available for reuse by the scientific community.

  1. OPENING ADDRESS: Heterostructures in Semiconductors

    NASA Astrophysics Data System (ADS)

    Grimmeiss, Hermann G.

    1996-01-01

    perspectives for future applications. We are most grateful that you agreed with the special format of the symposium which clearly does not follow conven- tional conferences. Allow me to call your special attention once again to two main differences: The presentations are not review papers praising already achieved break-throughs but introductions to a list of open questions and issues for which our understanding is still unsatisfactory. To give such presentations requires courage and scientific integrity. I would like to thank all speakers now already for their willingness to cope with such a difficult task. We have allocated at least 50 minutes for discussion after each presentation not only for discussing the paper as such but, if possible, to find answers to the open questions. If one or several participants in the audience during the discussion think they can contribute to improving our understanding of heterostructures, they are invited to write their ideas up and, if the referees agree, we are more than happy to publish these ideas in the proceedings. We admit that the program is rather demanding. For that reason, we plan to have a break on Thursday afternoon by first going to Denmark and touring the Hamlet castle of Kronborg. We then sail back to Sweden and will be hosted by the Krapperup castle where we will have a candle-light dinner and thereafter a baroque music concert featuring the Concerto Copenhagen. All participants, observers, and accompanying spouses are invited and we hope you will all enjoy the excur- sion. The local organising committee acknowledges with pleasure the financial and all other support received from the Nobel Foundation and the Nobel Institute of Physics as well as the initial initiative taken by the chairman of the Nobel Com- mittee for Physics, Prof. Nordling, who was the first to suggest this Nobel Symposium on "Heterostructures in Semicon- ductors". Special thanks also to the members of the program committee who have been of inestimable

  2. An address geocoding solution for Chinese cities

    NASA Astrophysics Data System (ADS)

    Zhang, Xuehu; Ma, Haoming; Li, Qi

    2006-10-01

    We introduce the challenges of address geocoding for Chinese cities and present a potential solution along with a prototype system that deal with these challenges by combining and extending current geocoding solutions developed for United States and Japan. The proposed solution starts by separating city addresses into "standard" addresses which meet a predefined address model and non-standard ones. The standard addresses are stored in a structured relational database in their normalized forms, while a selected portion of the non-standard addresses are stored as aliases to the standard addresses. An in-memory address index is then constructed from the address database and serves as the basis for real-time address matching. Test results were obtained from two trials conducted in the city Beijing. On average 80% matching rate were achieved. Possible improvements to the current design are also discussed.

  3. Open questions about giant viruses.

    PubMed

    Claverie, Jean-Michel; Abergel, Chantal

    2013-01-01

    The recent discovery of giant viruses exhibiting double-stranded DNA genomes larger than a million base pairs, encoding more than a thousand proteins and packed in near micron-sized icosahedral particles, opened a new and unexpected chapter in virology. As of today, these giant viruses and their closest relatives of lesser dimensions infect unicellular eukaryotes found in aquatic environments, but belonging to a wide diversity of early branching phyla. This broad phylogenetic distribution of hosts is consistent with the hypothesis that giant viruses originated prior to the radiation of the eukaryotic domain and/or might have been involved in the partition of nuclear versus cytoplasmic functions in ancestral cells. The distinctive features of the known giant viruses, in particular the recurrent presence of components of the translation apparatus in their proteome, raise a number of fundamental questions about their origin, their mode of evolution, and the relationship they may entertain with other dsDNA viruses, the genome size of which exhibits the widest distribution among all biological entities, from less than 5 kb to more than 1.25 Mb (a ratio of 1:250). At a more conceptual level, the convergence between the discovery of increasingly reduced parasitic cellular organisms and that of giant viruses exhibiting a widening array of cellular-like functions may ultimately abolish the historical discontinuity between the viral and the cellular world.

  4. Compilation of Agricultural Research, Education, and Extension Questions for Discussion. 104th Congress, 1st Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Agriculture.

    This volume compiles and reprints the responses of 37 organizations to a series of questions issued by the House Committee on Agriculture in anticipation of debates concerning the Research Title of the 1995 Farm Bill due for updating and revision. The questions address some of the following topics: the role of the federal government in…

  5. Input Consistency in the Acquisition of Questions in Bulgarian and English: A Hypothesis Testing Model

    ERIC Educational Resources Information Center

    Tornyova, Lidiya

    2011-01-01

    The goal of this dissertation is to address several major empirical and theoretical issues related to English-speaking children's difficulties with auxiliary use and inversion in questions. The empirical data on English question acquisition are inconsistent due to differences in methods and techniques used. A range of proposals about the source of…

  6. What Is Life? An Activity to Convey the Complexities of This Simple Question

    ERIC Educational Resources Information Center

    Prud'homme-Genereux, Annie

    2013-01-01

    "What is life?" This deceptively simple question lies at the heart of biology. In this activity, students work in groups to come up with their own definition using a set of prompting cards that differs for each team. In doing so, students gain an appreciation of the complexities of addressing this question. The activity takes approximately 60-90…

  7. Questions Often Asked about Special Education Services = Preguntas sobre los servicios de educacion especial.

    ERIC Educational Resources Information Center

    Kupper, Lisa, Ed.

    This guide, available in both English and Spanish, answers questions often asked by parents about special education services. Questions and answers address the following topics: where to begin if a parent believes a child needs special education services, services available to very young children, the evaluation process, the Individualized…

  8. A Case Study of Question Formations of the Saudi EFL Learners at Bisha University

    ERIC Educational Resources Information Center

    Ahmed Al-Hassaani, Abdulbari Mahboob

    2016-01-01

    This paper has studied the question formation techniques used by the Saudi students at Bisha University. It addresses the problems faced by the students in forming questions in English. The study has identified that a large number of the students suffer from the lack of proper grammar rules in forming various types of interrogative sentences and…

  9. Twenty questions about student errors

    NASA Astrophysics Data System (ADS)

    Fisher, Kathleen M.; Lipson, Joseph Isaac

    Errors in science learning (errors in expression of organized, purposeful thought within the domain of science) provide a window through which glimpses of mental functioning can be obtained. Errors are valuable and normal occurrences in the process of learning science. A student can use his/her errors to develop a deeper understanding of a concept as long as the error can be recognized and appropriate, informative feedback can be obtained. A safe, non-threatening, and nonpunitive environment which encourages dialogue helps students to express their conceptions and to risk making errors. Pedagogical methods that systematically address common student errors produce significant gains in student learning. Just as the nature-nurture interaction is integral to the development of living things, so the individual-environment interaction is basic to thought processes. At a minimum, four systems interact: (1) the individual problem solver (who has a worldview, relatively stable cognitive characteristics, relatively malleable mental states and conditions, and aims or intentions), (2) task to be performed (including relative importance and nature of the task), (3) knowledge domain in which task is contained, and (4) the environment (including orienting conditions and the social and physical context).Several basic assumptions underlie research on errors and alternative conceptions. Among these are: Knowledge and thought involve active, constructive processes; there are many ways to acquire, organize, store, retrieve, and think about a given concept or event; and understanding is achieved by successive approximations. Application of these ideas will require a fundamental change in how science is taught.

  10. Addressing submarine geohazards through scientific drilling

    NASA Astrophysics Data System (ADS)

    Camerlenghi, A.

    2009-04-01

    multi-platform drilling of the Nankai seismogenic zone. Scientific initiatives are flourishing to drive IODP towards the study of submarine geohazards. In the last three years international workshops, were held to address the topic: ESF-ECORD sponsored a Magellan Workshop focussed on submarine landslides (Barcelona, Spain, 2006); IODP sponsored a world-wide Geohazard Workshop (Portland, Oregon, 2007); ESF-ECORD sponsored another Magellan Workshop focussed on Mediterranean submarine geohazards (Luleå, Sweden, 2008). In addition, following the ECORD-Net Conference on the Deep Sea Frontier (Naples, Italy, 2006), the history, monitoring and prediction of geohazards was identified as one of the 6 major areas for a European science plan to integrate Ocean Drilling, Ocean Margin, and Seabed research. More than 200 scientists and private companies representatives have been mobilized world-wide to attend these meetings, from where it emerged that Ocean Drilling will play a key role in the future to answer the following basic open questions on submarine geohazards: - What is the frequency, magnitude, and distribution of geohazard events? - Do precursory phenomena exist and can they be recognized? - What are the physical and mechanical properties of materials prone to failure? - What are the roles of preconditioning vs. triggering in rapid seafloor deformation? - Can the tsunamigenic potential of past and future events be assessed? Within the global-ocean geohazards, worth of note is the attention given in this preparatory phase to submarine geohazards in the Mediterranean basin, a miniature ocean often called a "natural laboratory" because of the diversity of geological environments it contains. The coastline is very densely-populated, totalling 160 million inhabitants sharing 46,000 km of coastline. The Mediterranean is the World's leading holiday destination, receiving an average of 135 million visitors annually. Submarine landslides, volcanic flank collapses, volcanic island

  11. Computational strategies to address chromatin structure problems

    NASA Astrophysics Data System (ADS)

    Perišić, Ognjen; Schlick, Tamar

    2016-06-01

    While the genetic information is contained in double helical DNA, gene expression is a complex multilevel process that involves various functional units, from nucleosomes to fully formed chromatin fibers accompanied by a host of various chromatin binding enzymes. The chromatin fiber is a polymer composed of histone protein complexes upon which DNA wraps, like yarn upon many spools. The nature of chromatin structure has been an open question since the beginning of modern molecular biology. Many experiments have shown that the chromatin fiber is a highly dynamic entity with pronounced structural diversity that includes properties of idealized zig-zag and solenoid models, as well as other motifs. This diversity can produce a high packing ratio and thus inhibit access to a majority of the wound DNA. Despite much research, chromatin’s dynamic structure has not yet been fully described. Long stretches of chromatin fibers exhibit puzzling dynamic behavior that requires interpretation in the light of gene expression patterns in various tissue and organisms. The properties of chromatin fiber can be investigated with experimental techniques, like in vitro biochemistry, in vivo imagining, and high-throughput chromosome capture technology. Those techniques provide useful insights into the fiber’s structure and dynamics, but they are limited in resolution and scope, especially regarding compact fibers and chromosomes in the cellular milieu. Complementary but specialized modeling techniques are needed to handle large floppy polymers such as the chromatin fiber. In this review, we discuss current approaches in the chromatin structure field with an emphasis on modeling, such as molecular dynamics and coarse-grained computational approaches. Combinations of these computational techniques complement experiments and address many relevant biological problems, as we will illustrate with special focus on epigenetic modulation of chromatin structure.

  12. Regional Screening Levels Frequent Questions (May 2016)

    EPA Pesticide Factsheets

    Regional Screening Level RSL frequently asked question FAQ page provides risk assessors answers to common questions about the preliminary remediation goal PRG risk based concentration RBC and risk calculator for the assessment of human Health.

  13. Questions for Your Doctor: Your First Visit

    MedlinePlus

    The Testicular Cancer Resource Center Questions for your Doctor: Your First Visit This list of questions is intended to help ... cancer, be happy, but also be aware that testicular cancer is misdiagnosed as epididymitis or something similar almost ...

  14. What Questions Should I Ask My Doctor?

    MedlinePlus

    ... Trials Database Supporting Research Raising Awareness Our Blog Patient Education Pancreas News Basics of Pancreatic Cancer FAQs The ... Detection- Goggins Lab Sol Goldman Center Discussion Board Patient Education / Basics of Pancreatic Cancer Questions What questions should ...

  15. Questions and Answers for Architectural Coatings Rule

    EPA Pesticide Factsheets

    The EPA compiled this question and answer document from inquiries received after the publication of the 1999 final architectural coatings rule and from questions raised at meetings with industry associations.

  16. What Questions Do They Ask? Ausubel Rephrased.

    ERIC Educational Resources Information Center

    Spargo, Peter E.; Enderstein, L. Gus

    1997-01-01

    Investigates what questions elementary students would ask when presented with various situations relating to the natural environment. Findings reveal the extraordinary range of questions that elementary students have concerning the solar system and space. (JRH)

  17. Provocative Questions in Cancer: NCI Seminar

    Cancer.gov

    science writers' seminar to discuss various aspects of one of NCI’s signature efforts -- the Provocative Questions project. Discussion will focus on the scientific research that surrounds some of these questions.

  18. Two-Year-Old Children Differentiate Test Questions from Genuine Questions

    ERIC Educational Resources Information Center

    Grosse, Gerlind; Tomasello, Michael

    2012-01-01

    Children are frequently confronted with so-called "test questions". While genuine questions are requests for missing information, test questions ask for information obviously already known to the questioner. In this study we explored whether two-year-old children respond differentially to one and the same question used as either a genuine question…

  19. Introduction strategies raise key questions.

    PubMed

    Finger, W R; Keller, S

    1995-09-01

    Key issues that must be considered before a new contraceptive is introduced center on the need for a trained provider to begin or terminate the method, its side effects, duration of use, method's ability to meet users' needs and preferences, and extra training or staff requirements. Logistics and economic issues to consider are identifying a dependable way of effectively supplying commodities, planning extra services needed for the method, and cost of providing the method. Each contraceptive method presents a different side effect pattern and burdens the service delivery setting differently. The strategy developed to introduce or expand the 3-month injectable Depo-Provera (DMPA) can be used for any method. It includes a needs assessment and addresses regulatory issues, service delivery policies and procedures, information and training, evaluation, and other concerns. Viet Nam's needs assessment showed that Norplant should not be introduced until the service delivery system becomes stronger. Any needs assessment for expansion of contraceptive services should cover sexually transmitted disease/HIV issues. A World Health Organization strategy helps officials identify the best method mix for local situations. Introductory strategies must aim to improve the quality of family planning programs and expand choices. Many begin by examining existing data and conducting interviews with policymakers, users, providers, and women's health advocates. Introductory programs for Norplant focus on provider training, adequate counseling and informed consent for users, and ready access to removal. They need a well-prepared service delivery infrastructure. The first phase of the DMPA introductory strategy for the Philippines comprised a social marketing campaign and DMPA introduction at public clinics in 10 pilot areas with strong service delivery. Successful AIDS prevention programs show that people tend to use barrier methods when they are available. USAID is currently studying

  20. Better Questions and Answers Equal Success.

    ERIC Educational Resources Information Center

    Swicegood, Philip R.; Parsons, James L.

    1989-01-01

    Students with learning disabilities and behavior problems need instruction designed to increase active thinking and questioning skills. Described methods for teaching these skills include T. Raphael's question-answer relationships, A. Hahn's questioning strategy, reciprocal teaching, and the "ReQuest" procedure. Practice activities for…

  1. Questions and Answers About Nuclear Power Plants.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Washington, DC.

    This pamphlet is designed to answer many of the questions that have arisen about nuclear power plants and the environment. It is organized into a question and answer format, with the questions taken from those most often asked by the public. Topics include regulation of nuclear power sources, potential dangers to people's health, whether nuclear…

  2. Answering Wh- Questions About Sentences and Text.

    ERIC Educational Resources Information Center

    Singer, Murray

    1986-01-01

    Describes a study designed to identify the mental operations that contribute to people's ability to answer wh- questions, that is, questions which request information that plays a particular role in relation to some action or event. Wh- questions are signaled by interrogative pronouns and adverbs like who, what, when, and where. (SED)

  3. Answers to Your Questions About American Indians.

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

    Many of the frequent questions which arise concerning the relationship between Indians and the Federal Government are answered in this document. These questions and answers, in general, relate to Indians with whom the Federal government still retains a special relationship. Questions and answers pertain to the following areas: (1) the Indian…

  4. Wh- Questions and Individuals with Intellectual Disability

    ERIC Educational Resources Information Center

    Sanders, Eric

    2012-01-01

    The purpose of this study was to investigate the comprehension of questions beginning with different wh- question words presented in two referential conditions to individuals with intellectual disability (ID). Thirty-nine school-age participants completed a battery of who, what, where, when, why, and how questions with and without a picture…

  5. Memory, Knowledge, and the Answering of Questions.

    ERIC Educational Resources Information Center

    Norman, Donald A.

    An examination of the nature of memory reveals that the representation of knowledge cannot be separated from the uses of knowledge. The answering of questions is not a simple retrieval and response of stored information; rather the process is embedded in a general structural framework containing knowledge of the questioner, the question, and the…

  6. What Can We Learn from Students' Questions?

    ERIC Educational Resources Information Center

    Commeyras, Michelle

    1995-01-01

    Creating opportunities and encouraging student-centered questioning requires a special teacher-student dynamic. Students need to be empowered to ask questions. The article explores what teachers can learn from questions students ask, focusing on learning outcomes for teachers, and using a second-grade lesson on Harriet Tubman as an example. (SM)

  7. Questions That Science Teachers Find Difficult (II).

    ERIC Educational Resources Information Center

    Goodwin, Alan

    2003-01-01

    Presents some questions that science teachers find difficult. Focuses on three further questions relating to "simple" everyday situations that are normally explained in terms of the kinetic theory of matter. Identifies looking at the difference between chemical and physical changes as the most problematic question. (Author/YDS)

  8. Delivery of QTIiv2 Question Types

    ERIC Educational Resources Information Center

    Wills, Gary B.; Davis, Hugh C.; Gilbert, Lester; Hare, Jonathon; Howard, Yvonne; Jeyes, Steve; Millard, David; Sherratt, Robert

    2009-01-01

    The IMS Question and Test Interoperability (QTI) standard identifies 16 different question types which may be used in online assessment. While some partial implementations exist, the R2Q2 project has developed a complete solution that renders and responds to all 16 question types as specified. In addition, care has been taken in the R2Q2 project…

  9. How to Make Your Questions Essential

    ERIC Educational Resources Information Center

    Wiggins, Grant; Wilbur, Denise

    2015-01-01

    Good essential questions rarely emerge in the first draft. Common first-draft questions typically are convergent low-level questions designed to support content acquisition. They either point toward the one official "right" answer, or they elicit mere lists and thus no further inquiry. So how can teachers ensure that subsequent drafts…

  10. 47 CFR 13.215 - Question pools.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Question pools. 13.215 Section 13.215 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL RADIO OPERATORS Examination System § 13.215 Question pools. The question pool for each written examination element will be composed of...

  11. Teaching Students to Form Effective Questions

    ERIC Educational Resources Information Center

    Stafford, Tish

    2009-01-01

    The ability to question lies at the heart of human curiosity and is a necessary component of cognition. The author stresses that forming questions is essential to human thought and communication. As such, forming questions is a foundational process that cuts across curricular areas and is embedded in content standards across the nation, including…

  12. 32 CFR 316.7 - Questions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Questions. 316.7 Section 316.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY PRIVACY PROGRAM § 316.7 Questions. Questions on both the substance and procedure...

  13. 32 CFR 316.7 - Questions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Questions. 316.7 Section 316.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY PRIVACY PROGRAM § 316.7 Questions. Questions on both the substance and procedure...

  14. 32 CFR 316.7 - Questions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Questions. 316.7 Section 316.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY PRIVACY PROGRAM § 316.7 Questions. Questions on both the substance and procedure...

  15. 32 CFR 316.7 - Questions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Questions. 316.7 Section 316.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY PRIVACY PROGRAM § 316.7 Questions. Questions on both the substance and procedure...

  16. 32 CFR 316.7 - Questions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Questions. 316.7 Section 316.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY PRIVACY PROGRAM § 316.7 Questions. Questions on both the substance and procedure...

  17. The Contrast between Interrogatives and Questions.

    ERIC Educational Resources Information Center

    Huddleston, Rodney

    1994-01-01

    Explores the relation between interrogative, a category of grammatical form, and question, a category of meaning. Mismatches between interrogative phrases and questioned elements are also investigated. Two kinds of interrogative and three kinds of question are distinguished. (47 references) (Author/CK)

  18. Developing Qualitative Research Questions: A Reflective Process

    ERIC Educational Resources Information Center

    Agee, Jane

    2009-01-01

    The reflective and interrogative processes required for developing effective qualitative research questions can give shape and direction to a study in ways that are often underestimated. Good research questions do not necessarily produce good research, but poorly conceived or constructed questions will likely create problems that affect all…

  19. Teaching Culture: Questioning Perspectives on Our Practices

    ERIC Educational Resources Information Center

    Met, Myriam

    2010-01-01

    Despite years of training, teaching experience, reading professional literature, attending conferences, and learning from expert colleagues, when it comes to the teaching of culture, the author wishes she knew more answers to many critical questions. Her questions are framed by the basic questions that all curricula seek to answer: WHAT is the…

  20. 16 CFR 0.2 - Official address.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Official address. The principal office of the Commission is at Washington, DC. All communications to the Commission should be addressed to the Federal Trade Commission, 600 Pennsylvania Avenue, NW, Washington,...

  1. 16 CFR 0.2 - Official address.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Official address. The principal office of the Commission is at Washington, DC. All communications to the Commission should be addressed to the Federal Trade Commission, 600 Pennsylvania Avenue, NW, Washington,...

  2. 16 CFR 0.2 - Official address.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Official address. The principal office of the Commission is at Washington, DC. All communications to the Commission should be addressed to the Federal Trade Commission, 600 Pennsylvania Avenue, NW, Washington,...

  3. Planetary protection - some legal questions

    NASA Astrophysics Data System (ADS)

    Fasan, E.

    2004-01-01

    When we legally investigate the topic of Planetary Protection, we have to realise that there are primarily two very distinct parts of our juridical work: We have to study lexlata, theexistingapplicableLaw, especially Space Law, and also lexferenda, whatshouldbethe law . With this in mind, we have to deliberate the legal meaning of the notions "Planetary", and "Protection". About " Planetary": Our own Earth is our most important planet. At present only here do exist human beings, who are sensu strictu the only legal subjects. We make the law, we have to apply it, and we are to be protected as well as bound by it. But what is further meant by "Planetary"? Is it planets in an astronomical sense only, the nine planets which revolve around our fixed star, namely the sun, or is it also satellites, moving around most of these planets, as our own Moon circles Earth. "The Moon and other Celestial Bodies (C.B.)" are subject to Space Law, especially to International Treaties, Agreements, Resolutions of the UN, etc. I propose that they and not only the planets in an strictly astronomical sense are to be protected. But I do not think that the said notion also comprises asteroids, comets, meteorites, etc. although they too belong to our solar system. Our investigation comes to the result that such bodies have a different (lesser) legal quality. Also we have to ask Protectionfrom what ? From: Natural bodies - Meteorites, NEO Asteroids, Comets which could hit Earth or C.B.Artificial Objects: Space Debris threatening especially Earth and near Earth orbits.Terrestrial Life - no infection of other celestial bodies. Alien life forms which could bring about "harmful contamination" of Earth and the life, above all human life, there, etc. Here, astrobiological questions have to be discussed. Special realms on C.B. which should be protected from electronic "noise" such as craters SAHA or Deadalus on the Moon, also taking into account the "Common Heritage" Principle. Then, we have to

  4. Planetary protection - some legal questions

    NASA Astrophysics Data System (ADS)

    Fasan, E.

    When we legally investigate the topic of Planetary Protection, we have to realise that there are primarily two very distinct parts of our juridical work: We have to study lex lata, the existing applicable Law, especially Space Law, and also lex ferenda, what should be the law. With this in mind, we have to deliberate the legal meaning of "Planetary", and of "Protection". About "Planetary": Our own Earth is the most important planet. At present only here do exist human beings, who are sensu strictu the only legal subjects. We make the law, we have to apply it, and we are to be protected as well as bound by it. Then, we have to discuss what is further meant by "Planetary": Is it planets in an astronomical sense only, the nine planets which revolve around our fixed star, namely the sun, or is it also satellites, moving around most of these planets, as our own Moon circles Earth. "The Moon and other Celestial Bodies (C.B)" are subject to Space Law, especially to International Treaties, Agreements, Resolutions of the UN etc. I propose that they and not only the planets in an strictly astronomical sense are to be protected. But I do not think that the said notion also comprises asteroids, comets, meteorites etc. although they too belong to our solar system. Our investigation comes to the result that such bodies have a different (lesser) legal quality. Also we have to ask Protection from what? From: Natural bodies - Meteorites, NEO Asteroids, Comets which could hit Earth or C.B. Artificial Objects: Space Debris threatening especially Earth and near Earth orbits. Terrestrial Life - no infection of other celestial bodies. Alien life forms which could bring about "harmful contamination" of Earth and the life, above all human life, there etc. Here, astrobiological questions have to be discussed. Special realms on C.B. which should be protected from Electronic "Noise" such as craters SAHA or Deadalus on the Moon, also taking into account the "Common Heritage" Principle. Then

  5. Have the Answers to Common Legal Questions Concerning Nutrition Support Changed Over the Past Decade? 10 Questions for 10 Years.

    PubMed

    Barrocas, Albert; Cohen, Michael L

    2016-06-01

    Clinical nutrition specialists (CNSs) are often confronted with technological, ethical, and legal questions, that is, what can be done technologically, what should be done ethically, and what must be done legally, which conflict at times. The conflict represents a "troubling trichotomy" as discussed in the lead article of this issue of Nutrition in Clinical Practice (NCP). During Clinical Nutrition Week in 2006, a symposium covering these 3 topics was presented, and later that year, an article covering the same topic was published in NCP In this article, we revisit several legal questions/issues that were raised 10 years ago and discuss current answers and approaches. Some of the answers remain unchanged. Other answers have been modified by additional legislation, court decisions, or regulations. In addition, new questions/issues have arisen. Some of the most common questions regarding nutrition support involve the following: liability, informed consent, medical decisional incapacity vs legal competence, advance directive specificity, surrogate decision making, physician orders for life-sustaining treatment and electronic medical orders for life-sustaining treatment, legal definition of death, patient vs family decision making, the noncompliant patient, and elder abuse obligations. In the current healthcare environment, these questions and issues are best addressed via a transdisciplinary team that focuses on function rather than form. The CNS can play a pivotal role in dealing with these challenges by applying the acronym ACT: being Accountable and Communicating with all stakeholders while actively participating as an integral part of the transdisciplinary Team.

  6. 47 CFR 97.23 - Mailing address.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Mailing address. 97.23 Section 97.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO... name and mailing address. The mailing address must be in an area where the amateur service is...

  7. 47 CFR 97.23 - Mailing address.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Mailing address. 97.23 Section 97.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO... name and mailing address. The mailing address must be in an area where the amateur service is...

  8. 47 CFR 97.23 - Mailing address.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Mailing address. 97.23 Section 97.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO... name and mailing address. The mailing address must be in an area where the amateur service is...

  9. 47 CFR 97.23 - Mailing address.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Mailing address. 97.23 Section 97.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO... name and mailing address. The mailing address must be in an area where the amateur service is...

  10. 47 CFR 97.23 - Mailing address.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Mailing address. 97.23 Section 97.23 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO... name and mailing address. The mailing address must be in an area where the amateur service is...

  11. 37 CFR 41.10 - Correspondence addresses.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Correspondence addresses. 41... Correspondence addresses. Except as the Board may otherwise direct, (a) Appeals. Correspondence in an application... correspondence in an application or a patent involved in an appeal to the Board for which an address is...

  12. 37 CFR 41.10 - Correspondence addresses.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Correspondence addresses. 41... Correspondence addresses. Except as the Board may otherwise direct, (a) Appeals. Correspondence in an application... correspondence in an application or a patent involved in an appeal to the Board for which an address is...

  13. 47 CFR 13.10 - Licensee address.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Licensee address. 13.10 Section 13.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL RADIO OPERATORS General § 13.10 Licensee address. In accordance with § 1.923 of this chapter all applications must specify an address where...

  14. 32 CFR 516.7 - Mailing addresses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Mailing addresses. 516.7 Section 516.7 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION General § 516.7 Mailing addresses. Mailing addresses for organizations referenced...

  15. Medical Marijuana: More Questions than Answers

    PubMed Central

    Hill, Kevin P.

    2014-01-01

    With 23 states and the District of Columbia having enacted medical marijuana laws as of August 2014, it is important that psychiatrists be able to address questions about medical marijuana from patients, families, and other health care professionals. The author discusses the limited medical literature on synthetic cannabinoids and medical marijuana. The synthetic cannabinoids dronabinol and nabilone are approved by the United States Food and Drug Administration for nausea and vomiting associated with cancer chemotherapy and appetite stimulation in patients with wasting diseases such as acquired immunodeficiency syndrome (AIDS). Results of clinical trials of these agents for other conditions have varied widely thus far. In addition, few data are available on the use of the marijuana plant as a medical treatment. The author concludes that there is a clear need for additional research on possible medical uses of cannabinoids. He notes that discussions with prospective medical marijuana patients should emphasize the importance of communication among all parties due to the possible side effects of treatment with marijuana and its potential to interact with other medications the patient may be taking. Facilitating a thorough substance abuse consultation is one of most positive ways that psychiatrists, especially addiction psychiatrists, can make an impact as medical marijuana becomes increasingly common. A careful review of the prospective medical marijuana user's substance use history, co-occurring medical and psychiatric conditions, family history, and psychosocial stressors is essential in evaluating the potential risks of medical marijuana for these patients. The author concludes that psychiatrists can have a significant impact by increasing the likelihood that medical marijuana will be used in a safe and responsible way. PMID:25226202

  16. En Route to Seamless Statewide Education Data Systems: Addressing Five Cross-Cutting Concerns

    ERIC Educational Resources Information Center

    Conger, Sharmila Basu

    2008-01-01

    Student achievement depends upon successful passage through a series of transitions: elementary to middle school, middle school to high school, high school to college. Increasing the efficiency of successful transitions requires the collection and analysis of student data across these transition points. Yet long-standing separations between…

  17. Invited Address: James Joyce, Alice in Wonderland, the Rolling Stones, and Criminal Careers

    ERIC Educational Resources Information Center

    Piquero, Alex R.

    2011-01-01

    The study of criminal careers generally, and patterns of continuity and change in criminal offending in particular, has been a long-standing interest to social scientists across many disciplines. This article provides readers with an overview of this line of research. After an introduction to the criminal career perspective, the article presents…

  18. Questions for assessing higher-order cognitive skills: it's not just Bloom's.

    PubMed

    Lemons, Paula P; Lemons, J Derrick

    2013-01-01

    We present an exploratory study of biologists' ideas about higher-order cognition questions. We documented the conversations of biologists who were writing and reviewing a set of higher-order cognition questions. Using a qualitative approach, we identified the themes of these conversations. Biologists in our study used Bloom's Taxonomy to logically analyze questions. However, biologists were also concerned with question difficulty, the length of time required for students to address questions, and students' experience with questions. Finally, some biologists demonstrated an assumption that questions should have one correct answer, not multiple reasonable solutions; this assumption undermined their comfort with some higher-order cognition questions. We generated a framework for further research that provides an interpretation of participants' ideas about higher-order questions and a model of the relationships among these ideas. Two hypotheses emerge from this framework. First, we propose that biologists look for ways to measure difficulty when writing higher-order questions. Second, we propose that biologists' assumptions about the role of questions in student learning strongly influence the types of higher-order questions they write.

  19. 150 Student Questions on Solar Physics

    NASA Astrophysics Data System (ADS)

    Lopez, R. E.; Gross, N. A.; Knipp, D. J.

    2010-12-01

    The Center for Integrated Space Weather Modeling (CISM) holds a two-week Space Weather Summer School for introductory graduate students and space weather professionals to gain a system level understanding of the space environment and the effects of space weather. A typical day in the summer school consists of three morning lectures followed by an afternoon lab session. After the morning lectures, the participants are each asked to submit a question about the mornings topics on a question card. The lecturers then take the time to answer these questions prior to afternoon sessions. In the last 5 years over 1000 such question cards have been collected and cataloged. Despite detailed lectures by experts similar questions appear every year. We have analyzed over 150 questions related to the introductory lectures on solar physics and solar activity. Questions content was categorized using the AGU Index, and question sophistication was categorized using Bloom’s Taxonomy of Educational Objectives. Specific analysis results along with lists of questions will be presented. We hope that these results can be used to improve the lecture and classroom content and allow students to move beyond low level education objectives and ask more sophisticated questions.

  20. Zika Virus and Complications: Questions and Answers

    MedlinePlus

    ... spread of vector-borne diseases Mosquito surveillance and control What role does mosquito surveillance play in addressing ... in Aedes mosquito populations What role does mosquito control play in addressing Zika virus? Mosquito control is ...

  1. Multi Sensor Approach to Address Sustainable Development

    NASA Technical Reports Server (NTRS)

    Habib, Shahid

    2007-01-01

    The main objectives of Earth Science research are many folds: to understand how does this planet operates, can we model her operation and eventually develop the capability to predict such changes. However, the underlying goals of this work are to eventually serve the humanity in providing societal benefits. This requires continuous, and detailed observations from many sources in situ, airborne and space. By and large, the space observations are the way to comprehend the global phenomena across continental boundaries and provide credible boundary conditions for the mesoscale studies. This requires a multiple sensors, look angles and measurements over the same spot in accurately solving many problems that may be related to air quality, multi hazard disasters, public health, hydrology and more. Therefore, there are many ways to address these issues and develop joint implementation, data sharing and operating strategies for the benefit of the world community. This is because for large geographical areas or regions and a diverse population, some sound observations, scientific facts and analytical models must support the decision making. This is crucial for the sustainability of vital resources of the world and at the same time to protect the inhabitants, endangered species and the ecology. Needless to say, there is no single sensor, which can answer all such questions effectively. Due to multi sensor approach, it puts a tremendous burden on any single implementing entity in terms of information, knowledge, budget, technology readiness and computational power. And, more importantly, the health of planet Earth and its ability to sustain life is not governed by a single country, but in reality, is everyone's business on this planet. Therefore, with this notion, it is becoming an impractical problem by any single organization/country to bear this colossal responsibility. So far, each developed country within their means has proceeded along satisfactorily in implementing

  2. Question Classification Taxonomies as Guides to Formulating Questions for Use in Chemistry Classrooms

    ERIC Educational Resources Information Center

    Festo, Kayima

    2016-01-01

    Teacher questions play an important role in facilitating classroom discourse. Using appropriate question types and proper questioning techniques help to create reflective-active learners. Teacher questions can elicit students' explanations, elaboration of their ideas and thinking, and they can be used to disclose students' misconceptions. Despite…

  3. Correlation between Question Intonation and Focus of Interrogation--Evidence from French Dislocated Questions.

    ERIC Educational Resources Information Center

    Shen, Xiao-nan

    This study explores the relationship between question intonation patterns in French using dislocated questions and question-focus (Q- focus). A dislocated question is defined as an interrogative sentence whose sequence is interrupted by the topicalization of a constituent at the left ("Toi, tu viens?"), at the right (Tu viens,…

  4. Is There a Relationship between Chemistry Performance and Question Type, Question Content and Gender?

    ERIC Educational Resources Information Center

    Hudson, Ross D.

    2012-01-01

    This research inquires into the effectiveness of the two predominant forms of questions--multiple-choice questions and short-answer questions--used in the State University Entrance Examination for Chemistry including the relationship between performance and gender. It examines not only the style of question but also the content type examined…

  5. Teacher Communication Concerns Revisited: Calling into Question the Gnawing Pull towards Equilibrium

    ERIC Educational Resources Information Center

    Dannels, Deanna P.

    2015-01-01

    This study revisits the long-standing teacher communication concerns framework originating over three decades ago. Analysis of 10 years of contemporary GTA teacher communication concerns reveals a typology of 10 concerns, which taken together construct teaching as a process of negotiating relationships, managing identities, and focusing attention.…

  6. Military Medical Care: Questions and Answers

    DTIC Science & Technology

    2008-05-20

    Order Code RL33537 Military Medical Care : Questions and Answers Updated May 20, 2008 Richard A. Best Jr. Specialist in National Defense Foreign...control number. 1. REPORT DATE 20 MAY 2008 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Military Medical Care : Questions and...8-98) Prescribed by ANSI Std Z39-18 Military Medical Care : Questions and Answers Summary The primary mission of the military health system, which

  7. Discourse Integration Guided by the ‘Question under Discussion’

    PubMed Central

    Clifton, Charles; Frazier, Lyn

    2012-01-01

    What makes a discourse coherent? One potential factor has been discussed in the linguistic literature in terms of a Question under Discussion (QUD). This approach claims that discourse proceeds by continually raising explicit or implicit questions, viewed as sets of alternatives, or competing descriptions of the world. If the interlocutor accepts the question, it becomes the QUD, a narrowed set of alternatives to be addressed (Roberts, 1996/To appear). Three eye movement recording studies are reported that investigated the effect of a preceding explicit QUD (Experiment 1) or implicit QUD (Experiments 2 and 3) on the processing of following text. Experiment 1 revealed an effect of whether the question queried alternative propositions or alternative entities. Reading times in the answer were faster when the answer it provided was of the same semantic type as was queried. Experiment 2 tested QUDs implied by the alternative description of reality introduced by a non-actuality implicature trigger such as should X or want to X. The results, when combined with the results of Experiment 3 (which ruled out a possible alternative interpretation) showed disrupted reading of a following verb phrase that failed to resolve the implicit QUD (Did the discourse participant actually X?), compared to reading the same material in the absence of a clear QUD. The findings support an online role for QUDs in guiding readers’ structuring and interpretation of discourse. PMID:22683609

  8. Clostridium difficile Infection in Children: Current State and Unanswered Questions

    PubMed Central

    Tamma, Pranita D.; Sandora, Thomas J.

    2012-01-01

    The incidence of Clostridium difficile infection (CDI) in children has increased over the past decade. In recent years, new and intriguing data on pediatric CDI have emerged. Community-onset infections are increasingly recognized, even in children who have not previously received antibiotics. A hypervirulent strain is responsible for up to 20% of pediatric CDI cases. Unique risk factors for CDI in children have been identified. Advances in diagnostic testing strategies, including the use of nucleic acid amplification tests, have raised new questions about the optimal approach to diagnosing CDI in children. Novel therapeutic options are available for adult patients with CDI, raising questions about the use of these agents in children. Updated recommendations about infection prevention and control measures are now available. We summarize these recent developments in pediatric CDI in this review and also highlight remaining knowledge gaps that should be addressed in future research efforts. PMID:23687578

  9. Seeds of HOPE: a model for addressing social and economic determinants of health in a women's obesity prevention project in two rural communities.

    PubMed

    Benedict, Salli; Campbell, Marci; Doolen, Anne; Rivera, Imana; Negussie, Tezita; Turner-McGrievy, Gabrielle

    2007-10-01

    Socioeconomic status (SES) and income disparity are strong predictors of health, and health promotion interventions that address them are more likely to be meaningful to participants and to sustain positive effects. Seeds of HOPE is an innovative project that is the result of a long-standing collaboration between the University of North Carolina (UNC) Center for Health Promotion and Disease Prevention, a Centers for Disease Control and Prevention (CDC) Prevention Research Center, and communities in rural North Carolina. Initial formative work, including key informant interviews, community surveys, and focus groups, strengthened our understanding of the link between hope and health and the importance of addressing social and economic issues as part of our health promotion interventions. A Seeds of HOPE strategic plan was developed using a community-based participatory process and led to the idea to start Threads of HOPE, an enterprise that will serve as a business laboratory where women will produce and market a unique product and also learn business skills. Threads of HOPE will be a health-enhancing business and will serve as a training program for a new cadre of women entrepreneurs in two rural communities.

  10. Novel Duplicate Address Detection with Hash Function

    PubMed Central

    Song, GuangJia; Ji, ZhenZhou

    2016-01-01

    Duplicate address detection (DAD) is an important component of the address resolution protocol (ARP) and the neighbor discovery protocol (NDP). DAD determines whether an IP address is in conflict with other nodes. In traditional DAD, the target address to be detected is broadcast through the network, which provides convenience for malicious nodes to attack. A malicious node can send a spoofing reply to prevent the address configuration of a normal node, and thus, a denial-of-service attack is launched. This study proposes a hash method to hide the target address in DAD, which prevents an attack node from launching destination attacks. If the address of a normal node is identical to the detection address, then its hash value should be the same as the “Hash_64” field in the neighboring solicitation message. Consequently, DAD can be successfully completed. This process is called DAD-h. Simulation results indicate that address configuration using DAD-h has a considerably higher success rate when under attack compared with traditional DAD. Comparative analysis shows that DAD-h does not require third-party devices and considerable computing resources; it also provides a lightweight security resolution. PMID:26991901

  11. Ten questions on Kienbock's disease of the lunate.

    PubMed

    Dias, Joseph J; Lunn, Peter

    2010-09-01

    Kienböck's disease (Kienböck, 1910) affects the lunate bone in patients who are usually in their twenties, and present with pain, swelling and stiffness of the wrist. Almost every treatment currently suggested for Kienböck's disease is based on an hypothesis rather than proven knowledge. We treat it in the hope that what we are doing is logical and likely to benefit our patients. There are many questions that we should be prepared to answer and we list some we must address. A century after Kienböck's description of this disorder a number cannot yet be answered adequately. This paper explores areas of uncertainty.

  12. The science and questions surrounding chronic traumatic encephalopathy.

    PubMed

    Ban, Vin Shen; Madden, Christopher J; Bailes, Julian E; Hunt Batjer, H; Lonser, Russell R

    2016-04-01

    Recently, the pathobiology, causes, associated factors, incidence and prevalence, and natural history of chronic traumatic encephalopathy (CTE) have been debated. Data from retrospective case series and high-profile media reports have fueled public fear and affected the medical community's understanding of the role of sports-related traumatic brain injury (TBI) in the development of CTE. There are a number of limitations posed by the current evidence that can lead to confusion within the public and scientific community. In this paper, the authors address common questions surrounding the science of CTE and propose future research directions.

  13. Lifelong Persistence of Toxoplasma Cysts: A Questionable Dogma?

    PubMed

    Rougier, Solène; Montoya, Jose G; Peyron, François

    2017-02-01

    It is believed that infection by Toxoplasma gondii triggers a lifelong protective immunity due to the persistence of parasitic cysts which induce immunoprotection against reinfection. A review of the scientific literature since the 1950s did not yield any definitive data regarding the duration of cysts in the host or the presence of lifelong protective immunity, which led us to question this dogma. We put forward the hypothesis that sustained immunity to T. gondii requires repeated antigenic stimulations. The decline of seroprevalence recently observed in many countries might contribute to explain the loss of immunity. We address the potential consequences of this phenomenon, should it persist and worsen.

  14. Language Policy in the U.S.: Questions Addressing a Sea Change in Language in the U.S.

    ERIC Educational Resources Information Center

    Brecht, Richard D.; Rivers, William P.

    1999-01-01

    Language is important in the public life of the United States because of four factors: globalization; the global diffusion of democracy and self-determination; the wave of immigration to the United States from all corners of the world; and the unique role America plays as the sole military and economic superpower. These conditions make it…

  15. "Presidential Address." Political Pawns in an Educational Endgame: Reflections on Bryant, Briggs, and Some Twentieth-Century School Questions

    ERIC Educational Resources Information Center

    Graves, Karen

    2013-01-01

    "Newsweek" ran an article on "The Homosexual Teacher" in December 1978. At the end of a tumultuous two-year period framed by Anita Bryant's anti-gay campaign in South Florida and John Briggs' proposition to bar gay and lesbian educators from working in California public schools, reporters concluded, "Most homosexual…

  16. Salmonella enterica serovar Gallinarum: addressing fundamental questions in bacteriology sixty years on from the 9R vaccine.

    PubMed

    Wigley, Paul

    2017-04-01

    Sixty years on from Smith's seminal work on Fowl Typhoid vaccines, there is renewed interest in experimental avian salmonellosis and in particular the use of Salmonella enterica serovar Gallinarum as a tool to understand key features of bacterial evolution and host adaptation. In this short review we outline some of the recent advances in avian salmonellosis research that have coupled both the power of whole genome analysis and new tools to understand the host response to existing experimental infection models. These approaches are underpinning a fundamental understanding of Salmonella biology relevant to both the chicken and other avian and mammalian species.

  17. Epithelial Skin Biology: Three Decades of Developmental Biology, a Hundred Questions Answered and a Thousand New Ones to Address

    PubMed Central

    Fuchs, Elaine

    2016-01-01

    The mammalian skin epidermis and its hair and sweat gland appendages provide a protective barrier that retains essential body fluids, guards against invasion by harmful microbes, and regulates body temperature through the ability to sweat. At the interface between the external environment and the body, skin is constantly subjected to physical trauma and must also be primed to repair wounds in response to injury. In adults, the skin maintains epidermal homeostasis, hair regeneration, and wound repair through the use of its stem cells. This essay focuses on when stem cells become established during skin development and where these cells reside in adult epithelial tissues of the skin. I explore how skin stem cells maintain tissue homeostasis and repair wounds and how they regulate the delicate balance between proliferation and differentiation. Finally, I tackle the relation between skin cancer and mutations that perturb the regulation of stem cells. PMID:26970628

  18. Environmental Radiation Effects: A Need to Question Old Paradigms

    SciTech Connect

    Hinton, T.G.; Bedford, J.; Ulsh, B.; Whicker, F. Ward

    2003-03-27

    A historical perspective is given of the current paradigm that does not explicitly protect the environment from radiation, but instead, relies on the concept that if dose limits are set to protect humans then the environment is automatically protected as well. We summarize recent international questioning of this paradigm and briefly present three different frameworks for protecting biota that are being considered by the U.S. DOE, the Canadian government and the International Commission on Radiological Protection. We emphasize that an enhanced collaboration is required between what has traditionally been separated disciplines of radiation biology and radiation ecology if we are going to properly address the current environmental radiation problems. We then summarize results generated from an EMSP grant that allowed us to develop a Low Dose Irradiation Facility that specifically addresses effects of low-level, chronic irradiation on multiple levels of biological organization.

  19. Alternative Physics Examination Questions: Identification and Explanation of Different Discriminating Powers

    NASA Astrophysics Data System (ADS)

    Forster, Patricia A.

    2005-12-01

    The issue of unfairness arises in high-stakes public examinations when students choose questions from alternatives that are offered and marks on the alternatives turn out to be discrepant. This paper addresses and defines unfairness and discrepancy in the context of alternative questions in Physics Tertiary Entrance Examinations (TEE) in Western Australia. As well, I present an analysis of question characteristics that explain observed marks-differences. The characteristics mainly relate to the construction of the text of questions, the detail on diagrams, and requirements for calculation. The list of characteristics could inform the setting of compulsory as well as alternative examination questions. The paper includes a brief exploration of results by gender on the alternative Physics TEE questions.

  20. Children's questions: a mechanism for cognitive development.

    PubMed

    Chouinard, Michael M

    2007-01-01

    Preschoolers' questions may play an important role in cognitive development. When children encounter a problem with their current knowledge state (a gap in their knowledge, some ambiguity they do not know how to resolve, some inconsistency they have detected), asking a question allows them to get targeted information exactly when they need it. This information is available to them when they are particularly receptive to it, and because it comes as the result of their own disequilibrium, it may have depth of processing benefits. In that questions allow children to get information they need to move their knowledge structures closer to adult-like states, the ability to ask questions to gather needed information constitutes an efficient mechanism for cognitive development (referred to in this paper as the Information Requesting Mechanism [IRM]; this term is used because it includes question-asking and other information recruiting behaviors such as gestures, expressions, and vocalizations). However, the role of children's questions in their cognitive development has been largely overlooked. If questions are a force in cognitive development, the following must be true: (1) children must actually ask questions that gather information; (2) children must receive informative answers to their questions if they are able to be of use to cognitive development; (3) children must be motivated to get the information they request, rather than asking questions for other purposes such as attention; (4) the questions children ask must be relevant and of potential use to their cognitive development; (5) we must see evidence that children's questions help them in some way-that is, that they can ask questions for a purpose, and use the information they receive purposefully to successfully achieve some change of knowledge state. This monograph reports data on these points. Study 1 analyzed questions taken from four children's transcripts in the CHILDES database (age 1;2-5;1). This

  1. 47 CFR 97.523 - Question pools.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Question pools. 97.523 Section 97.523 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.523 Question pools. All VECs must cooperate in maintaining...

  2. 47 CFR 97.523 - Question pools.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Question pools. 97.523 Section 97.523 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.523 Question pools. All VECs must cooperate in maintaining...

  3. 47 CFR 97.523 - Question pools.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Question pools. 97.523 Section 97.523 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.523 Question pools. All VECs must cooperate in maintaining...

  4. 47 CFR 97.523 - Question pools.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Question pools. 97.523 Section 97.523 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.523 Question pools. All VECs must cooperate in maintaining...

  5. 47 CFR 97.523 - Question pools.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Question pools. 97.523 Section 97.523 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.523 Question pools. All VECs must cooperate in maintaining...

  6. Questions & Answers about Aeronautics and Space.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    Answers to 27 questions about aeronautics, space, and the National Aeronautics and Space Administration (NASA) are provided in this pamphlet. Among the topics dealt with in these questions are: costs of the space program; NASA's role in aeronautics; benefits received from the space program; why the United States hasn't developed means of rescuing…

  7. Children's Questions: A Mechanism for Cognitive Development

    ERIC Educational Resources Information Center

    Chouinard, Michelle M.

    2007-01-01

    Preschoolers' questions may play an important role in cognitive development. When children encounter a problem with their current knowledge state (a gap in their knowledge, some ambiguity they do not know how to resolve, some inconsistency they have detected), asking a question allows them to get targeted information exactly when they need it.…

  8. Question Generation for Learning by Reading

    DTIC Science & Technology

    2005-01-01

    Ruminator generates a question such as: “Is Gabriela Mistral central to the story of Chile?” Examples of the types of journalist questions generated by...generated by the system are: “Is Bin Laden associated with Saddam Hussein?” “How is Gabriela Mistral related to Augusto Pinochet Ugarte?” “Who

  9. Fixed-Response Questions with a Difference.

    ERIC Educational Resources Information Center

    Johnstone, Alex H.; Ambusaidi, Abdullah

    2002-01-01

    Offers three types of fixed-response questions that are designed to overcome drawbacks appearing in the conventional forms of fixed-response questions such as not allowing the examiner to investigate reasoning, background, or prevent guessing. (Contains 14 references.) (Author/YDS)

  10. Concealed Questions. In Search of Answers

    ERIC Educational Resources Information Center

    Frana, Ilaria

    2010-01-01

    This dissertation examines the semantic interpretation of various types of DPs in so-called concealed-question (CQ) constructions, as "Bill's phone number" in the sentence "John knows Bill's phone number". The peculiar characteristic of DP-CQs is that they are interpreted as having the meaning of an embedded question. So, for instance, the…

  11. Questions to Ask Your Liability Insurance Broker

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    2006-01-01

    This paper discusses some important questions to ask an insurance broker regarding liability insurance. The author based these questions on his interviews with Kathryn Hammerback, Craig Hammer, and Mike North: (1) Are centers covered when...?; (2) How can a center director cut costs on this policy?; (3) Is this an "occurrence" or a "claims-made"…

  12. Academic Oversight: Asking Questions, Building Bridges

    ERIC Educational Resources Information Center

    Wilson, E. B.

    2011-01-01

    The best way for trustees to fully understand and fulfill their responsibility to ensure that their institution is providing quality education and meeting academic goals is by asking appropriate questions. Collaboration among trustees, faculty members, and administrators is essential to framing questions from a strategic perspective. Just the act…

  13. The Effects of Questioning on Thinking Processes.

    ERIC Educational Resources Information Center

    Shiang, Ching-Pyng; McDaniel, Ernest

    This study investigated the effects of self-generated questions and external questions on thinking processes. Thirty-three college students acted as investigators in a computer simulation of a Congressional investigation into the Pearl Harbor attack. The simulation--known as "The Attack on Pearl Harbor: Cloud of Mystery?"--presented the…

  14. Question Asking and the Teaching of Writing.

    ERIC Educational Resources Information Center

    Odell, Lee

    This paper argues that provocative questions can be used by teachers to help students write. Described are a series of questions drawn from rhetorical theory, such as "How many times can I change focus so as to get the most complete understanding of a topic?""When does X occur?""Why does X occur?" and "What does X cause or prompt?" Several…

  15. Term weighting schemes for question categorization.

    PubMed

    Quan, Xiaojun; Liu, Wenyin; Qiu, Bite

    2011-05-01

    Term weighting has proven to be an effective way to improve the performance of text categorization. Very recently, with the development of user-interactive question answering or community question answering, there has emerged a need to accurately categorize questions into predefined categories. However, as a question is usually a piece of short text, can the existing term-weighting methods perform consistently in question categorization as they do in text categorization? The answer is not clear, since to the best of our knowledge, we have not seen any work related to this problem despite of its significance. In this study, we investigate the popular unsupervised and supervised term-weighting methods for question categorization. At the same time, we propose three new supervised term-weighting methods, namely, qf*icf, iqf*qf*icf, and vrf. Comparisons of them with existing unsupervised and supervised term-weighting methods are made through a series of experiments on question collections of Yahoo! Answers. The experimental results show that iqf*qf*icf achieves the best performance among all term-weighting methods, while qf*icf and vrf are also competitive for question categorization. Meanwhile, tf*OR is proven to be the most significant one among existing methods. In addition, iqf*qf*icf and vrf are also effective for long document categorization.

  16. Questioning Techniques: A Study of Instructional Practice

    ERIC Educational Resources Information Center

    Hill, Joan Buchanan

    2012-01-01

    This study took place in an independent all girls' school which serves over six hundred students in grades pre-kindergarten through twelve. This study seeks to answer the question: To what extent do teachers use questions to encourage deeper thinking and fuller responses. Through a review of literature, observations, interviews and analysis,…

  17. Training chemistry students to ask research questions

    NASA Astrophysics Data System (ADS)

    Hartford, Fred; Good, Ron

    In previous studies, science students have been trained to ask more and better questions through intensive instruction apart from the ongoing academic program. Cognitive strategies (such as questioning) are developed best, however, within the framework of an academic subject. In the current study, questioning skills were taught to high school chemistry students in the context of their laboratory experiments. Since both intellectual development and questioning skills are causally related to problem solving, the effect of intellectual development on the learning of questioning skills also was investigated. The Piagetian model of intellectual development was chosen for its demonstrated effects on many important aspects of science instruction. The number and quality of student research questions was measured by the Science Inquiry Assessment Instrument. The student's level of intellectual development was measured by the Classroom Test of Formal Operations. The twelve-week experimental treatment involved printed lessons which taught students to ask research questions in response to unanticipated observations in their regularly scheduled laboratory experiments. The pretest exaggerated the effect of this treatment. This effect, however, was significant among unpretested students, accounting for 14% of the post-test score variance. The level of intellectual development has no effect on these post-test scores. These important questioning skills can be acquired within the framework of the regularly scheduled classroom activities by high school chemistry students, irrespective of their level of Piagetian intellectual development.

  18. Using Questioning To Guide Student Thinking.

    ERIC Educational Resources Information Center

    van Zee, Emily; Minstrell, Jim

    1997-01-01

    Analyzes ways in which an experienced physics teacher uses questioning to guide student thinking during a benchmark discussion on measurement. Proposes that teachers may shift toward more reflective discourse by asking questions that help students clarify their meanings, consider various points of view, and monitor their own thinking. (Author/DKM)

  19. Prereading Questions and Online Text Comprehension

    ERIC Educational Resources Information Center

    Lewis, Mark Rose; Mensink, Michael C.

    2012-01-01

    Prereading questions can be an effective tool for directing students' learning. However, it is not always clear what the online effects of a set of prereading questions will be. In two experiments, this study investigated whether readers direct additional attention to and learn more from sentences that are potentially relevant to a set of…

  20. Processing the Curriculum through Quality Questioning

    ERIC Educational Resources Information Center

    Gregerson, Jessica

    2011-01-01

    In this inquiry-based project, student-generated questions became the basis for student-directed individual and group projects that provided practice with problem solving, critical thinking, and research skills while digging deeper into the Earth science curriculum. The author used her students' high-level questions to provide relevance,…

  1. Statistics Test Questions: Content and Trends

    ERIC Educational Resources Information Center

    Salcedo, Audy

    2014-01-01

    This study presents the results of the analysis of a group of teacher-made test questions for statistics courses at the university level. Teachers were asked to submit tests they had used in their previous two semesters. Ninety-seven tests containing 978 questions were gathered and classified according to the SOLO taxonomy (Biggs & Collis,…

  2. Adopted Children: A Question of Identity

    ERIC Educational Resources Information Center

    Mahmood, Samina; Visser, John

    2015-01-01

    This article draws upon a study completed in a specific school in Bangalore where most children enter at the pre-school level and continue till high school. While the particular children in the study constitute a small number--four--it was observed that questions of identity mainly arose when they started questioning the circumstances behind their…

  3. Question/Response Patterns in Indonesian Classrooms.

    ERIC Educational Resources Information Center

    Grow-Maienza, Janice

    A study of question and response patterns in middle and secondary schools in Indonesia is presented. The study examines questioning from the point of view of several previous studies. Interactions in 12 classes in English and in Bahasa Indonesian were videotaped in three middle schools and three secondary schools. Analysis of the data revealed…

  4. From Asking to Answering: Making Questions Explicit

    ERIC Educational Resources Information Center

    Washington, Gene

    2006-01-01

    "From Asking To Answering: Making Questions Explicit" describes a pedagogical procedure the author has used in writing classes (expository, technical and creative) to help students better understand the purpose, and effect, of text-questions. It accomplishes this by means of thirteen discrete categories (e.g., CLAIMS, COMMITMENT, ANAPHORA, or…

  5. The Right Questions, the Right Way

    ERIC Educational Resources Information Center

    Wiliam, Dylan

    2014-01-01

    According to Dylan Wiliam, the traditional classroom practice in which a teacher asks a question, students raise their hands, and the teacher calls on a volunteer does not actually provide much useful information--and it may even impede learning. When teachers ask questions in this way, they're only engaging the most confident students in the…

  6. Patterns and Punctuation: Learning to Question Language

    ERIC Educational Resources Information Center

    Schlessman, Elizabeth

    2011-01-01

    As teachers plan instruction--even instruction about punctuation--they have the opportunity to engage students' minds and create new labels: question-asking, problem-solving. How teachers teach embeds a vision of who they think kids are and what they think kids are capable of. Are they destined for a future of critical thinking, questioning,…

  7. Lunar interferometric astronomy: Some basic questions

    NASA Technical Reports Server (NTRS)

    Woolf, Neville

    1992-01-01

    The author examines some basic questions as to why there should be astronomical facilities on the far side of the moon. The questions are ones of appropriateness, i.e., is this a proper use for human resources, what the real goals are, and are the present concepts the best match for the goals.

  8. The American Indians: Answers to 101 Questions.

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

    Presented in a simple and straightforward manner, this publication answers questions basic to an understanding of the American Indian and his socioeconomic position in the United States. The following identify major areas covered and representative questions: (1) The Indian People (Who is an Indian?); (2) The Legal Status of Indians (Are Indians…

  9. "Wh"-Questions in the English Language

    ERIC Educational Resources Information Center

    Mowarin, Macaulay

    2011-01-01

    This paper analyzes "wh"-questions in the English Language based mainly on Chomsky's Minimalist Programme of transformational grammar as the theoretical model. The four main objectives of this paper are as follows: first, it undertakes a cross linguistic typological analysis of "wh"-questions and it then discusses the derivation of…

  10. 9/11: Reflections, Memories, and Questions

    ERIC Educational Resources Information Center

    Zingone, Joe

    2011-01-01

    What were you doing on September 11th? This seems like an obvious question to prompt conversations about the World Trade Center tragedy, but is it a good question to ask high school students a decade removed from the event? Many students now in high school were toddlers at the time. What do they really remember from that day? Are these memories…

  11. Asking the Wrong Questions about Leadership

    ERIC Educational Resources Information Center

    Graen, George B.

    2007-01-01

    Comments on the article by R. J. Hackman and R. Wageman (see record 2006-23492-007) which presented some directions for leadership research. Hackman and Wageman organized their article around their five reject-accept questions suggesting new directions. The current author discusses how each of the questions appears far too timid for real progress…

  12. Critical Questions for Space Human Factors

    NASA Technical Reports Server (NTRS)

    Woolford, Barbara; Bagian, Tandi

    2000-01-01

    Traditional human factors contributions to NASA's crewed space programs have been rooted in the classic approaches to quantifying human physical and cognitive capabilities and limitations in the environment of interest, and producing recommendations and standards for the selection or design of mission equipment. Crews then evaluate the interfaces, displays, or equipment, and with the assistance of human factors experts, improvements are made as funds, time, control documentation, and weight allow. We have come a long way from the early spaceflight days, where men with the ' right stuff were the solution to operating whatever equipment was given to them. The large and diverse Shuttle astronaut corps has impacted mission designs to accommodate a wide range of human capabilities and preferences. Yet with existing long duration experience, we have seen the need to address a different set of dynamics when designing for optimal crew performance: critical equipment and mission situations degrade, and human function changes with mission environment, situation, and duration. Strategies for quantifying the critical nature of human factors requirements are being worked by NASA. Any exploration-class mission will place new responsibilities on mission designers to provide the crew with the information and resources to accomplish the mission. The current duties of a Mission Control Center to monitor system status, detect degradation or malfunction, and provide a proven solution, will need to be incorporated into on-board systems to allow the crew autonomous decision-making. The current option to resupply and replace mission systems and resources, including both vehicle equipment and human operators, will be removed, so considerations of maintenance, onboard training, and proficiency assessment are critical to providing a self-sufficient crew. As we 'move in' to the International Space Station, there are tremendous opportunities to investigate our ability to design for autonomous

  13. Writing clinical scenarios for clinical science questions.

    PubMed

    Smith, Phil Em; Mucklow, John C

    2016-04-01

    Written knowledge assessments for physicians in training typically involve multiple-choice questions that use a clinical scenario in a single-best-answer format. The Royal College of Physicians Part 1 MRCP(UK) examination includes basic sciences themes that are challenging to assess through a clinical scenario. A realistic clinical setting based on everyday clinical practice and integral to the question is the clearest demonstration that the knowledge being assessed is clinically relevant. However, without special attention to detail, the scenario in a clinical science question can appear redundant or artificial. Reading unnecessary material frustrates candidates and threatens the reputation of the assessment. In this paper we discuss why a clinical scenario is important for basic science questions and offer advice on setting realistic and plausible clinical scenarios for such questions.

  14. Open questions in surface topography measurement: a roadmap

    NASA Astrophysics Data System (ADS)

    Leach, Richard; Evans, Christopher; He, Liangyu; Davies, Angela; Duparré, Angela; Henning, Andrew; Jones, Christopher W.; O'Connor, Daniel

    2015-03-01

    Control of surface topography has always been of vital importance for manufacturing and many other engineering and scientific disciplines. However, despite over one hundred years of quantitative surface topography measurement, there are still many open questions. At the top of the list of questions is ‘Are we getting the right answer?’ This begs the obvious question ‘How would we know?’ There are many other questions relating to applications, the appropriateness of a technique for a given scenario, or the relationship between a particular analysis and the function of the surface. In this first ‘open questions’ article we have gathered together some experts in surface topography measurement and asked them to address timely, unresolved questions about the subject. We hope that their responses will go some way to answer these questions, address areas where further research is required, and look at the future of the subject. The first section ‘Spatial content characterization for precision surfaces’ addresses the need to characterise the spatial content of precision surfaces. Whilst we have been manufacturing optics for centuries, there still isn’t a consensus on how to specify the surface for manufacture. The most common three methods for spatial characterisation are reviewed and compared, and the need for further work on quantifying measurement uncertainties is highlighted. The article is focussed on optical surfaces, but the ideas are more pervasive. Different communities refer to ‘figure, mid-spatial frequencies, and finish’ and ‘form, waviness, and roughness’, but the mathematics are identical. The second section ‘Light scattering methods’ is focussed on light scattering techniques; an important topic with in-line metrology becoming essential in many manufacturing scenarios. The potential of scattering methods has long been recognized; in the ‘smooth surface limit’ functionally significant relationships can be derived from first

  15. 49 CFR 1102.1 - How addressed.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false How addressed. 1102.1 Section 1102.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMMUNICATIONS § 1102.1 How addressed. All communications...

  16. 49 CFR 1102.1 - How addressed.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 8 2013-10-01 2013-10-01 false How addressed. 1102.1 Section 1102.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMMUNICATIONS § 1102.1 How addressed. All communications...

  17. 49 CFR 1102.1 - How addressed.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 8 2014-10-01 2014-10-01 false How addressed. 1102.1 Section 1102.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMMUNICATIONS § 1102.1 How addressed. All communications...

  18. 49 CFR 1102.1 - How addressed.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 8 2012-10-01 2012-10-01 false How addressed. 1102.1 Section 1102.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMMUNICATIONS § 1102.1 How addressed. All communications...

  19. 49 CFR 1102.1 - How addressed.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false How addressed. 1102.1 Section 1102.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMMUNICATIONS § 1102.1 How addressed. All communications...

  20. Public Address Systems. Specifications - Installation - Operation.

    ERIC Educational Resources Information Center

    Palmer, Fred M.

    Provisions for public address in new construction of campus buildings (specifications, installations, and operation of public address systems), are discussed in non-technical terms. Consideration is given to microphones, amplifiers, loudspeakers and the placement and operation of various different combinations. (FS)

  1. 49 CFR 369.6 - Address.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS REPORTS OF MOTOR CARRIERS § 369.6 Address. The following address must be used by motor carriers when submitting a report, requesting an exemption from filing...

  2. 16 CFR 0.2 - Official address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Official address. 0.2 Section 0.2 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.2... 20580, unless otherwise specifically directed. The Commission's Web site address is www.ftc.gov....

  3. Approaches for Resolving Dynamic IP Addressing.

    ERIC Educational Resources Information Center

    Foo, Schubert; Hui, Siu Cheung; Yip, See Wai; He, Yulan

    1997-01-01

    A problem with dynamic Internet protocol (IP) addressing arises when the Internet connection is through an Internet provider since the IP address is allocated only at connection time. This article examines a number of online and offline methods for resolving the problem. Suggests dynamic domain name system (DNS) and directory service look-up are…

  4. 37 CFR 41.10 - Correspondence addresses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Correspondence addresses. 41....10 Correspondence addresses. Except as the Board may otherwise direct, (a) Appeals. Correspondence in... all other correspondence in an application or a patent involved in an appeal to the Board for which...

  5. 37 CFR 41.10 - Correspondence addresses.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Correspondence addresses. 41....10 Correspondence addresses. Except as the Board may otherwise direct, (a) Appeals. Correspondence in... all other correspondence in an application or a patent involved in an appeal to the Board for which...

  6. 37 CFR 41.10 - Correspondence addresses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Correspondence addresses. 41....10 Correspondence addresses. Except as the Board may otherwise direct, (a) Appeals. Correspondence in... all other correspondence in an application or a patent involved in an appeal to the Board for which...

  7. History Forum Addresses Creation/Evolution Controversy.

    ERIC Educational Resources Information Center

    Schweinsberg, John

    1997-01-01

    A series of programs entitled Creationism and Evolution: The History of a Controversy was presented at the University of Alabama in Huntsville. The controversy was addressed from an historical and sociological, rather than a scientific perspective. Speakers addressed the evolution of scientific creationism, ancient texts versus sedimentary rocks…

  8. 34 CFR 674.44 - Address searches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Address searches. 674.44 Section 674.44 Education..., DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Due Diligence § 674.44 Address searches. (a) If mail... litigation; (2) The account is assigned to the United States; or (3) The account is written off under §...

  9. 34 CFR 674.44 - Address searches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Address searches. 674.44 Section 674.44 Education..., DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Due Diligence § 674.44 Address searches. (a) If mail... litigation; (2) The account is assigned to the United States; or (3) The account is written off under §...

  10. Forms of Address in Chilean Spanish

    ERIC Educational Resources Information Center

    Bishop, Kelley; Michnowicz, Jim

    2010-01-01

    The present investigation examines possible social and linguistic factors that influence forms of address used in Chilean Spanish with various interlocutors. A characteristic of the Spanish of Chile is the use of a variety of forms of address for the second person singular, "tu", "vos", and "usted", with corresponding…

  11. Image compression using address-vector quantization

    NASA Astrophysics Data System (ADS)

    Nasrabadi, Nasser M.; Feng, Yushu

    1990-12-01

    A novel vector quantization scheme, the address-vector quantizer (A-VQ), is proposed which exploits the interblock correlation by encoding a group of blocks together using an address-codebook (AC). The AC is a set of address-codevectors (ACVs), each representing a combination of addresses or indices. Each element of the ACV is an address of an entry in the LBG-codebook, representing a vector-quantized block. The AC consists of an active (addressable) region and an inactive (nonaddressable) region. During encoding the ACVs in the AC are reordered adaptively to bring the most probable ACVs into the active region. When encoding an ACV, the active region is checked, and if such an address combination exists, its index is transmitted to the receiver. Otherwise, the address of each block is transmitted individually. The SNR of the images encoded by the A-VQ method is the same as that of a memoryless vector quantizer, but the bit rate is by a factor of approximately two.

  12. Challenges Still to Be Appropriately Addressed

    NASA Astrophysics Data System (ADS)

    Maurette, Michel

    This section includes a heteroclite set of questions and comments of colleagues, which have still to be fully answered. Progress in science occurs not only with a few spectacular achievements that are generally cleverly advertised by funding agencies and the prestigious journals, but also by incessant questioning. They remain in the shadow for a while because you have to wait for an answer that might never come.

  13. Automated measurement of printer effective addressability

    NASA Astrophysics Data System (ADS)

    Cooper, Brian E.; Eid, Ahmed H.; Rippetoe, Edward E.

    2014-01-01

    When evaluating printer resolution, addressability is a key consideration. Addressability defines the maximum number of spots or samples within a given distance, independent of the size of the spots when printed. Effective addressability is the addressability demonstrated by the final, printed output. It is the minimum displacement possible between the centers of printed objects. In this paper, we present a measurement procedure for effective addressability that offers an automated way to experimentally determine the addressability of the printed output. It requires printing, scanning, and measuring a test target. The effective addressability test target contains two types of elements, repeated to fill the page: fiducial lines and line segments. The fiducial lines serve as a relative reference for the incremental displacements of the individual line segments, providing a way to tolerate larger-scale physical distortions in the printer. An ordinary reflection scanner captures the printed test target. By rotating the page on the scanner, it is possible to measure effective addressability well beyond the scanner's sampling resolution. The measurement algorithm computes the distribution of incremental displacements, forming either a unimodal or bimodal histogram. In the latter case, the mean of the second (non-zero) peak indicates the effective addressability. In the former case, the printer successfully rendered the target's resolution, requiring another iteration of the procedure after increasing the resolution of the test target. The algorithm automatically estimates whether the histogram is unimodal or bimodal and computes parameters describing the quality of the measured histogram. Several experiments have refined the test target and measurement procedure, including two round-robin evaluations by the ISO WG4 committee. Results include an analysis of approximately 150 printed samples. The effective addressability attribute and measurement procedure are included in

  14. Assessment of physicians’ addressing sexuality in elderly patients with chronic pain

    PubMed Central

    Cherpak, Guilherme Liausu; dos Santos, Fânia Cristina

    2016-01-01

    ABSTRACT Objective To determine the frequency with which physicians address their older adult patients with chronic pain about the issue of sexuality. Methods It is a cross sectional, descriptive, analytical study in which physicians answered a questionnaire comprising questions related to addressing the issue of sexuality during appointments. Results A sample of 155 physicians was obtained, 63.9% stated they did not address sexuality in medical interviews and 23.2% did it most of the time. The main reasons for not addressing were lack of time, fear of embarrassing the patient and technical inability to address the issue. Conclusion There is a need to develop strategies to increase and improve addressing of sexuality in elderly patients with chronic pain, in order to have better quality of life. PMID:27462890

  15. 42 CFR 136.412 - What questions must the IHS ask as part of the background investigation?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Child Protection and Family Violence Prevention § 136.412 What questions must the IHS ask as part of the... occurrence, and the name and address of the police department or court involved. (2) Has the individual...

  16. 42 CFR 136.412 - What questions must the IHS ask as part of the background investigation?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Child Protection and Family Violence Prevention § 136.412 What questions must the IHS ask as part of the... occurrence, and the name and address of the police department or court involved. (2) Has the individual...

  17. 42 CFR 136.412 - What questions must the IHS ask as part of the background investigation?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Child Protection and Family Violence Prevention § 136.412 What questions must the IHS ask as part of the... occurrence, and the name and address of the police department or court involved. (2) Has the individual...

  18. Smartphone use to answer clinical questions: a descriptive study of APNs.

    PubMed

    Grabowsky, Adelia

    2015-01-01

    This study examines the use of smartphones by Alabama Advanced Practice Nurses to find information to address clinical questions and seeks to describe the types of questions answered using smartphones; barriers to information seeking; apps and online resources perceived as most helpful; and training/resource needs. Information collected in this study can be used by libraries that serve nursing students to develop training and resources to assist both nursing students and practicing nurses to become more efficient and effective information seekers.

  19. The Technology of the Question: Structure and Use of Questions in Educational Technology

    ERIC Educational Resources Information Center

    Hokanson, Brad

    2015-01-01

    This writing looks at an elemental aspect of learning and communication, the question, and contends that questions can be viewed as a technology for education. Questions that we ask in the classroom, online, or in discussion can shape learning and develop skills in students, and they should be more systematically employed in education. This…

  20. Cognitive and emotional reactions to questions in the Comparison Question Test.

    PubMed

    MacNeill, A Luke; Bradley, M T; Cullen, M C; Arsenault, Andrea M

    2014-04-01

    The effect of situational factors on perceptions of items on the polygraph Comparison Question Test (CQT) was assessed. In an initial experiment, 86 students (30 men, 56 women; M age = 20.3 yr., SD = 4.0) imagined one of eight scenarios that varied by guilt or innocence, the commission of a real crime or mock crime, and interrogation by a police officer or a professor. They then rated generic CQT questions for importance and emotional concern. All participants rated crime-relevant questions as being more important than past-crime comparison questions. "Guilty" participants also rated these questions as being more emotionally concerning, but "innocent" participants showed no differences in their ratings of concern for the two question types. Interrogator or crime type did not affect the general pattern of responding. A second experiment involving 80 students (21 men, 58 women, 1 non-specified; M age = 22.5 yr., SD = 7.3) replaced the generic CQT questions with content-specific questions developed by the participant. Those imagining guilt showed no differencesin their ratings of relevant and comparison questions, whereas those imagining innocence rated comparison questions as more concerning. Again, interrogator type and crime type had little effect on results. Overall these findings indicated distinctions in cognitive and emotional appraisal for CQT questions, with the nature of emotional concern dependent on guilt/innocence status and the personal relevance of comparison questions. Evidence suggests that the CQT is robust to other situational factors, such as crime type and interrogator type.

  1. Beginning EFL Teachers' Beliefs about Quality Questions and Their Questioning Practices

    ERIC Educational Resources Information Center

    Pham, Ly Ngoc Khanh; Hamid, M. Obaidul

    2013-01-01

    Motivated by the scarcity of research that examines the impact of teacher beliefs on their actual practices in Vietnam, this study investigated the relationship between teachers' beliefs about quality questions and their questioning behaviours in terms of questioning purposes, content focus, students' cognitive level, wording and syntax. Thirteen…

  2. On framing the research question and choosing the appropriate research design.

    PubMed

    Parfrey, Patrick S; Ravani, Pietro

    2015-01-01

    Clinical epidemiology is the science of human disease investigation with a focus on diagnosis, prognosis, and treatment. The generation of a reasonable question requires definition of patients, interventions, controls, and outcomes. The goal of research design is to minimize error, to ensure adequate samples, to measure input and output variables appropriately, to consider external and internal validities, to limit bias, and to address clinical as well as statistical relevance. The hierarchy of evidence for clinical decision-making places randomized controlled trials (RCT) or systematic review of good quality RCTs at the top of the evidence pyramid. Prognostic and etiologic questions are best addressed with longitudinal cohort studies.

  3. Astronaut Jeff Williams Answers Your Questions

    NASA Video Gallery

    Expedition 22 Commander Jeff Williams, aboard the International Space Station 220 miles above Earth, responds to questions posted on YouTube concerning the station's orientation, life in space and ...

  4. Response to Questions on Presentation to NAS

    SciTech Connect

    Meier, W R

    2011-03-17

    Response to questions on the presentation 'Overview to Chamber and Power Plant Designs for IFE' made at the 1/29-31 meeting of the National Academies Committee on the Prospects for Inertial Confinement Fusion Energy Systems.

  5. Frequently Asked Questions about Nutrition Labeling

    MedlinePlus

    ... About Teaching Gardens Teaching Gardens-See Our Gardens Teaching Gardens Supporters Why We Garden Weight Management Body Mass Index (BMI) Body Mass Index In Adults (BMI Calculator for Adults) Frequently Asked Questions (FAQs) ...

  6. Five Big Questions about Cable Television

    ERIC Educational Resources Information Center

    Molenda, Michael

    1972-01-01

    It is the purpose of this article to answer a few of the major questions which most often arise in relation to the still embryonic but complex new medium of cable television. (22 references) (Author/SJ)

  7. Body Lice Frequently Asked Questions (FAQs)

    MedlinePlus

    ... Treatment FAQs Malathion FAQs Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ... Frequently Asked Questions (FAQs) Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ...

  8. Head Lice: Frequently Asked Questions (FAQs)

    MedlinePlus

    ... Treatment FAQs Malathion FAQs Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ... Frequently Asked Questions (FAQs) Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ...

  9. Head Lice: Treatment Frequently Asked Questions (FAQs)

    MedlinePlus

    ... Treatment FAQs Malathion FAQs Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ... Frequently Asked Questions (FAQs) Epidemiology & Risk Factors Disease Biology Diagnosis Treatment Prevention & Control Resources for Health Professionals ...

  10. Roth 401(k): asking the right questions.

    PubMed

    Joyner, James F

    2006-01-01

    Roth 401(k) provisions are a newly available feature of 401(k) plans. Roth 401(k) provisions are after-tax savings that generally are tax-free at the time of distribution. Questions arise for plan sponsors about whether the new feature is beneficial, and to whom, and what needs to be done if the plan sponsor decides to offer this provision to its employees. This article tries to answer some of those common questions, including a simple computational analysis to try to answer the important question of how much an employee-participant genuinely benefits from this savings approach. Some practical issues of implementation are touched on, and some unanswered questions are identified.

  11. AgrAbility: Frequently Asked Questions

    MedlinePlus

    ... AgrAbility Services Equipment and Vehicle Modifications Financing-Related Matters Other Modifications Other Disability and Agricultural-related questions Main Menu Home About AgrAbility State Projects Directory The Toolbox AT Database Resources Veterans & ...

  12. FAQ: General Questions about West Nile Virus

    MedlinePlus

    ... Public Service Videos General Questions About West Nile Virus Recommend on Facebook Tweet Share Compartir On This ... West Nile virus cases? What is West Nile virus? West Nile virus is an arthropod-borne virus ( ...

  13. Recruiting Students into Nursing: Prior Questions.

    ERIC Educational Resources Information Center

    Hipps, Opal S.

    1983-01-01

    Raises fundamental questions regarding student recruitment: (1) why recruit students into nursing? (2) what are the issues that determine whether a school should have a nursing program? and (3) what are students being recruited into? (JOW)

  14. Classroom Thought, Teacher Questions, and Student Analysis

    ERIC Educational Resources Information Center

    Wilen, William W.; Hogg, James

    1976-01-01

    Discussed is the need for teachers to improve their effectiveness in classroom skills such as questioning techniques. An instructor cognitive operation index is presented. For journal availability, see SO 505 192. (Author/DB)

  15. The Energy Question: Problems and Alternatives

    ERIC Educational Resources Information Center

    Nesbitt, William A.

    1973-01-01

    Some ideas for teaching about the energy crisis are developed in this article. The author suggests related inquiry questions and suggests techniques for clarification of interrelationships. Graphs and data related to the energy crisis are included. (SM)

  16. Olympics: Questions & Answers on the Major Events.

    ERIC Educational Resources Information Center

    Gibbon, Alan

    This book presents background information on the major Olympic events with a question-answer format. Events considered include track and field, swimming, diving, boxing, weightlifting, the equestrian events, and gymnastics. Line drawings illustrate the text. (MM)

  17. Frequently Asked Questions about Genetic Counseling

    MedlinePlus

    ... used on this page Frequently Asked Questions About Genetic Counseling What are genetic professionals and what do ... see a geneticist or other specialist? What are genetic professionals and what do they do? Genetics professionals ...

  18. Frequently Asked Questions about Genetic Disorders

    MedlinePlus

    ... used on this page Frequently Asked Questions About Genetic Disorders What are genetic disorders? A genetic disorder is a disease caused ... significant risk of developing the disease. . Geneticists group genetic disorders into three categories: Monogenetic disorders are caused ...

  19. Frequently Asked Questions about Genetic Testing

    MedlinePlus

    ... sobre las pruebas genéticas Frequently Asked Questions About Genetic Testing What is genetic testing? What can I ... find more information about genetic testing? What is genetic testing? Genetic testing uses laboratory methods to look ...

  20. Question Generation via Overgenerating Transformations and Ranking

    DTIC Science & Technology

    2009-01-01

    the sentence Francium was discov- ered by Marguerite Perey in France in 1939,2 the transducer produces the following questions: • Where was francium ...discovered by Marguerite Perey in 1939? • When was francium discovered by Marguerite Perey in France? • Was francium discovered by Marguerite Perey in...France in 1939? • By what was francium discovered in France in 1939? Of course, the last question ought to be By whom was.... This error is due to