Science.gov

Sample records for address unresolved issues

  1. Bigeye Bomb: Unresolved Development Issues

    DTIC Science & Technology

    1989-08-11

    Program Evaluation and Methodology Division B-21 1376 D IC August 11, 1989 ,, , The Honorable Dante B. Fascell - Chairman, Committee on Foreign...lliotoxic- ity is a method of measuring the lethality of the generated agent. Page 3 GAO/PEMD-89-27 Bigeye Bomb: Unresolved Developmental Issues B-211376...Physical Systems roram Evaluation eas, (202) 275-3092 and Methodology James If. Solomon, Assistant Director Division, Washington Kwai Cheng-Chan

  2. Unresolved Issues of Cooperative Learning.

    ERIC Educational Resources Information Center

    Cook, Stuart W.

    Proposals to use interracial/cross-ethnic learning teams in desegregated classrooms raise issues from research that demonstrate the complicated nature of the relationship between learning teams and classroom interracial relations. According to the research, relationships are affected by the characteristics of learning teams, namely…

  3. Local Area Network Management: An Unresolved Issue.

    ERIC Educational Resources Information Center

    Howden, Norman

    1989-01-01

    Discussion of management issues involved with local area networks (LAN) among information organizations focuses on a project at the University of North Texas that was designed to investigate problems associated with LAN. Topics discussed include purchasing decisions for hardware and software, and integration among various groups of users. (Eight…

  4. Energy crisis: Unresolved issues and enduring legacies

    SciTech Connect

    Lewis, D.L.

    1996-12-31

    The energy crisis of 1973--1974 was a pivotal event in twentieth-century American history. In the wake of the Vietnam War, it exposed the nation`s economic vulnerability to foreign powers and precipitated an awareness of limits to the exploitation of natural resources. Further, it forced Americans and the American government in particular to think about the future of energy production and consumption in novel ways and made such thinking more imperative than ever. Twenty years later, questions about the energy crisis persist. What were the underlying causes of the crisis. What has been learned from it. How has it affected current energy policies. Will another energy crisis occur in the future. In the book, David Lewis Feldman brings together a wide range of energy policy experts to address these questions and explore the appropriate role of governments and markets in ensuring a stable, economical, and sustainable energy supply.

  5. Extrinsic and Intrinsic Motivation at 30: Unresolved Scientific Issues

    ERIC Educational Resources Information Center

    Reiss, Steven

    2005-01-01

    The undermining effect of extrinsic reward on intrinsic motivation remains unproven. The key unresolved issues are construct invalidity (all four definitions are unproved and two are illogical); measurement unreliability (the free-choice measure requires unreliable, subjective judgments to infer intrinsic motivation); inadequate experimental…

  6. Quantum dots in nanomedicine: recent trends, advances and unresolved issues.

    PubMed

    Volkov, Yuri

    2015-12-18

    The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including "classical" semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems.

  7. Addressing Social Issues.

    ERIC Educational Resources Information Center

    Schoebel, Susan

    1991-01-01

    Maintains that advertising can help people become more aware of social responsibilities. Describes a successful nationwide newspaper advertising competition for college students in which ads address social issues such as literacy, drugs, teen suicide, and teen pregnancy. Notes how the ads have helped grassroots programs throughout the United…

  8. National Technology Standards for K-12 Schools: A Case Study of Unresolved Issues in Public Relations

    ERIC Educational Resources Information Center

    Mullen, Carol A.; Kealy, William A.; Sullivan, Ashley

    2004-01-01

    This article addresses an important need--the dissemination of information relating to technology as a public relations tool--and the associated exigency for administrator and teacher technology training. Specifically, we identify the increased expectations for the performance of school leaders and teachers, as well as unresolved issues in public…

  9. Extrinsic and intrinsic motivation at 30: Unresolved scientific issues.

    PubMed

    Reiss, Steven

    2005-01-01

    The undermining effect of extrinsic reward on intrinsic motivation remains unproven. The key unresolved issues are construct invalidity (all four definitions are unproved and two are illogical); measurement unreliability (the free-choice measure requires unreliable, subjective judgments to infer intrinsic motivation); inadequate experimental controls (negative affect and novelty, not cognitive evaluation, may explain "undermining" effects); and biased metareviews (studies with possible floor effects excluded, but those with possible ceiling effects included). Perhaps the greatest error with the undermining theory, however, is that it does not adequately recognize the multifaceted nature of intrinsic motivation (Reiss, 2004a). Advice to limit the use of applied behavior analysis based on "hidden" undermining effects is ideologically inspired and is unsupported by credible scientific evidence.

  10. Nuclear Forces from Chiral EFT: The Unresolved Issues

    NASA Astrophysics Data System (ADS)

    Machleidt, R.

    2011-05-01

    In recent years, there has been substantial progress in the derivation of nuclear forces from chiral effective field theory (EFT). Accurate two-nucleon forces have been constructed at next-to-next-to-next-to-leading order (N3LO) and applied (together with three-nucleon forces at NNLO) to nuclear few- and many-body systems—with a good deal of success. This may suggest that the 80-year old nuclear force problem has finally been cracked. Not so! Some pretty basic issues are still unresolved. In this talk, I focus on the two most pressing ones, namely, subleading many-body forces and the proper renormalization of the two-nucleon potential.

  11. Dietary copper and human health: Current evidence and unresolved issues.

    PubMed

    Bost, Muriel; Houdart, Sabine; Oberli, Marion; Kalonji, Esther; Huneau, Jean-François; Margaritis, Irène

    2016-05-01

    Although copper (Cu) is recognized as an essential trace element, uncertainties remain regarding Cu reference values for humans, as illustrated by discrepancies between recommendations issued by different national authorities. This review examines human studies published since 1990 on relationships between Cu intake, Cu balance, biomarkers of Cu status, and health. It points out several gaps and unresolved issues which make it difficult to assess Cu requirements. Results from balance studies suggest that daily intakes below 0.8 mg/day lead to net Cu losses, while net gains are consistently observed above 2.4 mg/day. However, because of an incomplete collection of losses in all studies, a precise estimation of Cu requirements cannot be derived from available data. Data regarding the relationship between Cu intake and potential biomarkers are either too preliminary or inconclusive because of low specificity or low sensitivity to change in dietary Cu over a wide range of intakes. Results from observation and intervention studies do not support a link between Cu and a risk of cardiovascular disease, cognitive decline, arthritis or cancer for intakes ranging from 0.6 to 3mg/day, and limited evidence exists for impaired immune function in healthy subjects with a very low (0.38 mg/day) Cu intake. However, data from observation studies should be regarded with caution because of uncertainties regarding Cu concentration in various foods and water. Further studies that accurately evaluate Cu exposure based on reliable biomarkers of Cu status are needed.

  12. Exercise hemorheology: classical data, recent findings and unresolved issues.

    PubMed

    Connes, Philippe; Simmonds, Michael J; Brun, Jean-Frederic; Baskurt, Oguz K

    2013-01-01

    The present review focuses on the past and recent knowledge in the field of exercise hemorheology and presents some unresolved issues for opening discussion. Acute exercise is associated with a rise in hematocrit which results in an increase in blood viscosity. Whereas increased blood viscosity was previously viewed as having negative consequences for cardiovascular function and aerobic performance, recent findings suggest dynamic changes in blood viscosity might be useful for vascular function during exercise by increasing nitric oxide production. Other determinants of blood viscosity are altered by exercise (e.g., decreased red blood cell deformability, increased red blood cell aggregation and plasma viscosity) and may, independent of the associated effect on blood viscosity, directly modulate aerobic capacity. However, the data published on the effects of exercise on the hemorheology are not consistent, with some studies showing decreased, unchanged, or increased red blood cell deformability/aggregation when compared with rest. These discrepancies seem to be related to the exercise protocol investigated, the population tested or the methodogy utilized for hemorheological measurements. Finally, this review focuses on the effects of exercise training (i.e. chronic physical activity) on the hemorheological profile of healthy individuals and patients with cardiovascular and metabolic disorders.

  13. Numerical Simulations of Some Unresolved Issues in Diocotron Stability

    NASA Astrophysics Data System (ADS)

    Mason, Grant W.; Spencer, Ross L.

    2003-10-01

    Several unresolved issues concerning the growth or decay of diocotron modes of nonneutral plasmas in Malmberg-Penning traps were presented at a recent workshop(Workshop on Non-Neutral Plasmas---2003, July 7-11, 2003, Santa Fe, New Mexico. To appear in AIP Conference Proceedings.) 1) Fajans and Pasquini report that, contrary to infinite length models, flat-topped (n(r) = constant) electron columns are violently unstable for non-maxwellian velocity distributions. 2) Driscoll and Kabantsev report that magnetic mirror analogs of electrostatically created trapped-particle asymmetry modes fail to appear in experiments. 3) Kabantsev and Driscoll report that small numbers of positive ions added to electron columns are diocotron unstable, with implications for antihydrogen formation experiments. 4) Driscoll and Kabantsev report that the decay of electrostatically confined asymmetry modes scales with axial magnetic field for low rigidity as B-1 whereas simulations show a B-2 behavior for low rigidity. We report on progress in simulations of these various effects with a detailed particle-in-cell code (Inferno).

  14. Gestational diabetes mellitus. Unresolved issues and future research directions.

    PubMed Central

    Okun, N.; Verma, A.; Demianczuk, N.

    1997-01-01

    OBJECTIVE: To summarize the controversial aspects of gestational diabetes (GDM) and introduce readers to possible relevant research questions that could be examined to provide clinicians with good-quality data on which to base decisions about this relatively common pregnancy-related issue. DATA SOURCES AND STUDY SELECTION: Ongoing review of the English literature related to GDM. Sources were not restricted to prospective, controlled trials, as these are severely limited in number. SYNTHESIS: Controversial issues include the relevance of GDM to clinically meaningful outcomes in the index pregnancy, the effectiveness of current therapy in altering these outcomes, and the resultant questionable relevance of routine screening and diagnosis of an entity with as yet uncertain significance in pregnancy. CONCLUSIONS: Suggested questions to be addressed in multicentre controlled trials include randomization with respect to screening and with respect to treatment. Until such trials are completed, continuing with a standard approach to screening, diagnosis, and treatment, such as that suggested by the third international workshop on GDM, is recommended. PMID:9626427

  15. Connective Tissue Disease-Associated Interstitial Lung Diseases: Unresolved Issues.

    PubMed

    Aparicio, Irene Jarana; Lee, Joyce S

    2016-06-01

    Interstitial lung disease (ILD) complicating connective tissue disorders, such as scleroderma and rheumatoid arthritis, is associated with significant morbidity and mortality. Progress has been made in our understanding of these collective diseases; however, there are still many unanswered questions. In this review, we describe the current views on epidemiology, clinical presentation, treatment, and prognosis in patients with connective tissue disease (CTD)-associated ILD. We also highlight several areas that remain unresolved and in need of further investigation, including interstitial pneumonia with autoimmune features, histopathologic phenotype, and pharmacologic management. A multidisciplinary and multidimensional approach to diagnosis, management, and investigation of CTD-associated ILD patients is essential to advance our understanding of the epidemiology and pathobiology of this challenging group of diseases.

  16. Neuroprotective properties of citicoline: facts, doubts and unresolved issues.

    PubMed

    Grieb, Pawel

    2014-03-01

    Citicoline is the generic name of the pharmaceutical substance that chemically is cytidine-5'-diphosphocholine (CDP-choline), which is identical to the natural intracellular precursor of phospholipid phosphatidylcholine. Following injection or ingestion, citicoline is believed to undergo quick hydrolysis and dephosphorylation to yield cytidine and choline, which then enter the brain separately and are used to resynthesize CDP-choline inside brain cells. Neuroprotective activity of citicoline has been repeatedly shown in preclinical models of brain ischaemia and trauma, but two recent, large, pivotal clinical trials have revealed no benefits in ischaemic stroke and traumatic brain injury. However, the substance seems to be beneficial in some slowly advancing neurodegenerative disorders such as glaucoma and mild vascular cognitive impairment. This paper critically discusses issues related to the clinical pharmacology of citicoline, including its pharmacokinetics/biotransformation and pharmacodynamics/mode of action. It is concluded that at present, there is no adequate description of the mechanism(s) of the pharmacological actions of this substance. The possibility should be considered and tested that, in spite of apparently fast catabolism, the intact citicoline molecule or the phosphorylated intermediate products of its hydrolysis, cytidine monophosphate and phosphocholine, are pharmacologically active.

  17. Status of safety issues at licensed power plants: TMI Action Plan requirements; unresolved safety issues; generic safety issues; other multiplant action issues. Supplement 3

    SciTech Connect

    Not Available

    1993-12-01

    As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, the NRC established a program for publishing an annual report on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was initially compiled and reported in three NUREG-series volumes. Volume 1, published in March 1991, addressed the status of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). The first annual supplement, which combined these volumes into a single report and presented updated information as of September 30, 1991, was published in December 1991. The second annual supplement, which provided updated information as of September 30, 1992, was published in December 1992. Supplement 2 also provided the status of licensee implementation and NRC verification of other multiplant action (MPA) issues not related to TMI Action Plan requirements, USIs, or GSIs. This third annual NUREG report, Supplement 3, presents updated information as of September 30, 1993. This report gives a comprehensive description of the implementation and verification status of TMI Action Plan requirements, safety issues designated as USIs, GSIs, and other MPAs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. Additionally, this report serves as a follow-on to NUREG-0933, ``A Prioritization of Generic Safety Issues,`` which tracks safety issues until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees.

  18. Mentoring in Educational Settings: Unresolved Issues and Unanswered Questions. WEEA Digest.

    ERIC Educational Resources Information Center

    McAuliffe, Anne, Ed.

    This digest contains the following two articles on mentoring: "Mentoring in Educational Settings: Unresolved Issues and Unanswered Questions" (Olga M. Welch); and "Learning from the Field: Mentoring Projects in Field-based Settings" (Heidi Lynch). The first article describes mentoring in general and mentoring in the schools, examines some studies…

  19. Brain Death in Pediatric Patients in Japan: Diagnosis and Unresolved Issues

    PubMed Central

    ARAKI, Takashi; YOKOTA, Hiroyuki; FUSE, Akira

    2016-01-01

    Brain death (BD) is a physiological state defined as complete and irreversible loss of brain function. Organ transplantation from a patient with BD is controversial in Japan because there are two classifications of BD: legal BD in which the organs can be donated and general BD in which the organs cannot be donated. The significance of BD in the terminal phase remains in the realm of scientific debate. As indicated by the increasing number of organ transplants from brain-dead donors, certain clinical diagnosis for determining BD in adults is becoming established. However, regardless of whether or not organ transplantation is involved, there are many unresolved issues regarding BD in children. Here, we will discuss the historical background of BD determination in children, pediatric emergencies and BD, and unresolved issues related to pediatric BD. PMID:26548741

  20. Central unresolved issues in thermal energy storage for building heating and cooling

    SciTech Connect

    Swet, C.J.; Baylin, F.

    1980-07-01

    This document explores the frontier of the rapidly expanding field of thermal energy storage, investigates unresolved issues, outlines research aimed at finding solutions, and suggests avenues meriting future research. Issues related to applications include value-based ranking of storage concepts, temperature constraints, consistency of assumptions, nomenclature and taxonomy, and screening criteria for materials. Issues related to technologies include assessing seasonal storage concepts, diurnal coolness storage, selection of hot-side storage concepts for cooling-only systems, phase-change storage in building materials, freeze protection for solar water heating systems, and justification of phase-change storage for active solar space heating.

  1. Addressing Transgender Issues in Schools

    ERIC Educational Resources Information Center

    Cavanagh, Marian

    2016-01-01

    As mainstream media focus more attention on transgender issues, and as anti-discrimination laws evolve, a shift is taking place on campuses. Many schools now include gender identity and expression in their inclusivity work and seek to establish policies and procedures to support transgender students and their families. It's not an easy task. In…

  2. Containment-emergency-sump performance. Technical findings related to Unresolved Safety Issue A-43. [PWR

    SciTech Connect

    Not Available

    1983-04-01

    This report summarizes key technical findings related to the Unresolved Safety Issue A-43, Containment Emergency Sump Performance, and provides recommendations for resolution of attendant safety issues. The key safety questions relate to: (a) effects of insulation debris on sump performance; (b) sump hydraulic performance as determined by design features, submergence, and plant induced effects, and (c) recirculation pump performance wherein air and/or particulate ingestion can occur. The technical findings presented in this report provide information relevant to the design and performance evaluation of the containment emergency sump.

  3. Universal leucodepletion: an overview of some unresolved issues and the highlights of lessons learned.

    PubMed

    Seghatchian, Jerard

    2003-10-01

    Universal leucodepletion (ULD) has been introduced in several countries based on the evidence that selective leucodepletion improves the clinical safety of blood components and based on animal studies that TSE infectivity is 5-7 times higher in the buffy coat than in plasma. Therefore it is perceivable that the removal of the buffy coat, by filtration, removing both leucocytes and platelets, may prove beneficial in reducing the potential risk of transmission of variant CJD by blood components. The implementation of a ULD policy has created some new requirements: Validation/standardisation of various leucodepletion processes to ensure compliance with set specifications. Standardisation/harmonisation of sampling and low leucocyte counting technologies to ensure the interchangeability of results nationally. The establishment of external quality assessment schemes on 'real' leucodepleted products where the cells come in contact with the filter matrix, to monitor the low leucocyte counting performance, nationally. Assessment of filtration-induced generation/retention of major biological response modifiers (BRM), having potential for the development of transfusion reactions. Using these approaches we have identified that, while the overall leucodepletion performance has improved following harmonisation/standardisation of the operational and counting technologies, there are still some unresolved problems and ULD alone may not provide complete protection from some viral transmission such as HTLV and CMV infections or reduction of bacterial sepsis and generation of some BRM. Moreover, ULD has not fully abrogated febrile non-haemolytic transfusion reactions (FNHTR). Therefore the key issue is not the 3-4 log(10) reduction of residual leucocytes but the design of new generation filters or leucodepletion processes with better performance characteristics, to further reduce some specific leucocyte subsets and their fragments as well as reduce the activation of coagulation

  4. Addressing Issues Related to Technology and Engineering

    ERIC Educational Resources Information Center

    Technology Teacher, 2008

    2008-01-01

    This article presents an interview with Michael Hacker and David Burghardt, codirectors of Hoftra University's Center for Technological Literacy. Hacker and Burghardt address issues related to technology and engineering. They argue that teachers need to be aware of the problems kids are facing, and how to present these problems in an engaging…

  5. Federal Offices That Address Women's Issues.

    ERIC Educational Resources Information Center

    Weber, Patricia A.; And Others

    This directory contains a listing of federal offices that address women's issues. Among the departments and agencies included are: the executive branch and the executive agencies departments of agriculture, commerce, defense (Air Force, Army, Coast Guard, Marine Corps, National Guard and Navy), education, health and human services, housing and…

  6. 255 Agreements, not 293 Unresolved Issues, on the Proposed High-Level Waste Repository at Yucca Mountain, Nevada.

    NASA Astrophysics Data System (ADS)

    Leslie, B. W.

    2002-05-01

    The U.S. Nuclear Regulatory Commission (NRC) is an independent regulatory agency whose mission is to ensure that public health, safety, and the environment are protected when nuclear materials are used. The Nuclear Waste Policy Act (NWPA) authorized NRC to develop licensing criteria for disposal of spent nuclear fuel and high-level radioactive waste in the proposed geologic repository at Yucca Mountain, Nevada. NRC is also required by the NWPA to interact with the U.S. Department of Energy (DOE), the potential license applicant, prior to the submission of a potential license application. Finally, the NWPA requires NRC to provide preliminary comments on "...the extent to which the at-depth site characterization analysis and waste form proposal for such site seem to be sufficient for inclusion in any application by the Secretary for licensing of such site as a repository" to DOE for inclusion in any DOE site recommendation. In November 2001 NRC published the final licensing criteria and provided the Secretary of Energy with the NRC's preliminary comments regarding a possible geologic repository at Yucca Mountain. NRC's comments were subsequently included in a site recommendation made by the Secretary of Energy, and approved by the President, in February 2002. NRC's preliminary comments reflect many years of extensive pre-licensing interaction among the NRC staff, DOE, and various stakeholders. NRC staff engaged DOE in an issue resolution process on key technical issues and identified additional information that DOE would need to provide in any license application. As part of the issue resolution process NRC also obtained DOE's agreement to provide acceptable responses to the requests for information by the time of any license application. The issue resolution agreements, which totaled 293, have been characterized as being unresolved issues. However, NRC's preliminary comments (these and NRC's issue resolution agreements with DOE are available at our website, noted

  7. Physical forcing and physical/biochemical variability of the Mediterranean Sea: a review of unresolved issues and directions for future research

    NASA Astrophysics Data System (ADS)

    Malanotte-Rizzoli, P.; Artale, V.; Borzelli-Eusebi, G. L.; Brenner, S.; Crise, A.; Gacic, M.; Kress, N.; Marullo, S.; Ribera d'Alcalà, M.; Sofianos, S.; Tanhua, T.; Theocharis, A.; Alvarez, M.; Ashkenazy, Y.; Bergamasco, A.; Cardin, V.; Carniel, S.; Civitarese, G.; D'Ortenzio, F.; Font, J.; Garcia-Ladona, E.; Garcia-Lafuente, J. M.; Gogou, A.; Gregoire, M.; Hainbucher, D.; Kontoyannis, H.; Kovacevic, V.; Kraskapoulou, E.; Kroskos, G.; Incarbona, A.; Mazzocchi, M. G.; Orlic, M.; Ozsoy, E.; Pascual, A.; Poulain, P.-M.; Roether, W.; Rubino, A.; Schroeder, K.; Siokou-Frangou, J.; Souvermezoglou, E.; Sprovieri, M.; Tintoré, J.; Triantafyllou, G.

    2014-05-01

    This paper is the outcome of a workshop held in Rome in November 2011 on the occasion of the 25th anniversary of the POEM (Physical Oceanography of the Eastern Mediterranean) program. In the workshop discussions, a number of unresolved issues were identified for the physical and biogeochemical properties of the Mediterranean Sea as a whole, i.e., comprising the Western and Eastern sub-basins. Over the successive two years, the related ideas were discussed among the group of scientists who participated in the workshop and who have contributed to the writing of this paper. Three major topics were identified, each of them being the object of a section divided into a number of different sub-sections, each addressing a specific physical, chemical or biological issue: 1. Assessment of basin-wide physical/biochemical properties, of their variability and interactions. 2. Relative importance of external forcing functions (wind stress, heat/moisture fluxes, forcing through straits) vs. internal variability. 3. Shelf/deep sea interactions and exchanges of physical/biogeochemical properties and how they affect the sub-basin circulation and property distribution. Furthermore, a number of unresolved scientific/methodological issues were also identified and are reported in each sub-section after a short discussion of the present knowledge. They represent the collegial consensus of the scientists contributing to the paper. Naturally, the unresolved issues presented here constitute the choice of the authors and therefore they may not be exhaustive and/or complete. The overall goal is to stimulate a broader interdisciplinary discussion among the scientists of the Mediterranean oceanographic community, leading to enhanced collaborative efforts and exciting future discoveries.

  8. Rational Rhymes for Addressing Common Childhood Issues

    ERIC Educational Resources Information Center

    Warren, Jeffrey M.

    2011-01-01

    Music-based interventions are valuable tools counselors can use when working with children. Specific types of music-based interventions, such as songs or rhymes, can be especially pertinent in addressing the thoughts, feelings, and behaviors of children. Rational-emotive behavior therapy (REBT) provides a therapeutic framework that encourages…

  9. Controversies and unresolved issues in tuberculosis prevention and control: a low-burden-country perspective.

    PubMed

    Abubakar, Ibrahim; Stagg, Helen R; Cohen, Ted; Mangtani, Punam; Rodrigues, Laura C; Pimpin, Laura; Watson, John M; Squire, S Bertel; Zumla, Alimuddin

    2012-05-15

    Despite declining incidence in most high-income countries, tuberculosis shows no signs of disappearing in the near future. Although surveillance data from most Western European countries show relatively stable declines in the rate of tuberculosis over the past several decades, some have reported either an increasing rate or a decelerating pace of reduction in recent years. The burden of disease now disproportionately affects high-risk groups such as migrants, homeless persons, and prisoners. In view of the concentration of cases in urban areas and high-risk deprived groups, interventions that may not be efficient when applied to the general population may be highly cost effective when targeted at high-risk groups. In this article, we examine some controversial elements of tuberculosis prevention and control in low-burden countries and recommend issues for further research. In particular, we assess current evidence on the duration of protection by BCG vaccine, the screening of migrants and hard-to-reach groups, and the use of preventive therapy for contacts of cases of infectious multidrug-resistant tuberculosis. This analysis is presented from the perspective of low-tuberculosis-burden, high-income countries attempting to eliminate tuberculosis.

  10. Resolution of Unresolved Safety Issue A-48, Hydrogen control measures and effects of hydrogen burns on safety equipment

    SciTech Connect

    Ferrell, C.M.; Soffer, L.

    1989-09-01

    Unresolved Safety Issue (USI) A-48 arose as a result of the large amount of hydrogen generated and burned within containment during the Three Mile Island accident. This issue covers hydrogen control measures for recoverable degraded-core accidents for all boiling-water reactors (BWRs) and those pressurized-water reactors (PWRs) with ice-condenser containments. The Commission and the nuclear industry have sponsored extensive research in this area, which has led to significant revision of the Commission's hydrogen control regulations, given in Title 10, Code of Federal Regulations, Part 50 (10 CFR 50), Section 50.44. BWRs having Mark I and II containments are presently required to operate with inerted containment atmospheres that effectively prevent hydrogen combustion. BWRs with Mark III containments and PWRs with ice-condenser containments are now required to be equipped with hydrogen control systems to protect containment integrity and safety systems inside containment. Industry has chosen to use hydrogen igniter systems to burn hydrogen produced in a controlled fashion to prevent damage. An independent review by a Committee of the National Research Council concluded that, for most accident scenarios, current regulatory requirements make it highly unlikely that hydrogen detonation would be the cause of containment failure. On the basis of the extensive research effort conducted and current regulatory requirements, including their implementation, the staff concludes that no new regulatory guidance on hydrogen control for recoverable degraded-core accidents for these types of plants is necessary and that USI A-48 is resolved.

  11. Clinical Neuropathology practice guide 5-2015: MGMT methylation pyrosequencing in glioblastoma: unresolved issues and open questions.

    PubMed

    Bienkowski, Michal; Berghoff, Anna S; Marosi, Christine; Wöhrer, Adelheid; Heinzl, Harald; Hainfellner, Johannes A; Preusser, Matthias

    2015-01-01

    O6-methylguanine-methyltransferase (MGMT) promoter methylation status has prognostic and, in the subpopulation of elderly patients, predictive value in newly diagnosed glioblastoma. Therefore, knowledge of the MGMT promoter methylation status is important for clinical decision-making. So far, MGMT testing has been limited by the lack of a robust test with sufficiently high analytical performance. Recently, one of several available pyrosequencing protocols has been shown to be an accurate and robust method for MGMT testing in an intra- and interlaboratory ring trial. However, some uncertainties remain with regard to methodological issues, cut-off definitions, and optimal use in the clinical setting. In this article, we highlight and discuss several of these open questions. The main unresolved issues are the definition of the most relevant CpG sites to analyze for clinical purposes and the determination of a cut-off value for dichotomization of quantitative MGMT pyrosequencing results into "MGMT methylated" and "MGMT unmethylated" patient subgroups as a basis for further treatment decisions.

  12. Displaced Homemakers: Unresolved Issues.

    ERIC Educational Resources Information Center

    Zawada, Mary Ann

    1980-01-01

    Problems of today's displaced homemakers overlap with those of women in the 1960s. Problems of women seeking employment are similar to those of minority groups, older workers and welfare recipients. Recent legislation has expanded to fulfill some of the needs of women returning to the labor force. (Author/BEF)

  13. NIH Research Addresses Aging Issues and Disparities in Oral Health

    MedlinePlus

    ... please turn JavaScript on. Feature: Oral Health and Aging NIH Research Addresses Aging Issues and Disparities in Oral Health Past Issues / ... What types of research is NIDCR conducting on aging and oral health? We’re currently funding basic ...

  14. Unresolved issues for the disposal of remote-handled transuranic waste in the Waste Isolation Pilot Plant

    SciTech Connect

    Silva, M.K.; Neill, R.H.

    1994-09-01

    The purpose of the Waste Isolation Pilot Plant (WIPP) is to dispose of 176,000 cubic meters of transuranic (TRU) waste generated by the defense activities of the US Government. The envisioned inventory contains approximately 6 million cubic feet of contact-handled transuranic (CH TRU) waste and 250,000 cubic feet of remote handled transuranic (RH TRU) waste. CH TRU emits less than 0.2 rem/hr at the container surface. Of the 250,000 cubic feet of RH TRU waste, 5% by volume can emit up to 1,000 rem/hr at the container surface. The remainder of RH TRU waste must emit less than 100 rem/hr. These are major unresolved problems with the intended disposal of RH TRU waste in the WIPP. (1) The WIPP design requires the canisters of RH TRU waste to be emplaced in the walls (ribs) of each repository room. Each room will then be filled with drums of CH TRU waste. However, the RH TRU waste will not be available for shipment and disposal until after several rooms have already been filled with drums of CH TRU waste. RH TRU disposal capacity will be loss for each room that is first filled with CH TRU waste. (2) Complete RH TRU waste characterization data will not be available for performance assessment because the facilities needed for waste handling, waste treatment, waste packaging, and waste characterization do not yet exist. (3) The DOE does not have a transportation cask for RH TRU waste certified by the US Nuclear Regulatory Commission (NRC). These issues are discussed along with possible solutions and consequences from these solutions. 46 refs.

  15. Pivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved Issues

    PubMed Central

    Zouein, Fouad A.; Altara, Raffaele; Chen, Qun; Lesnefsky, Edward J.; Kurdi, Mazen; Booz, George W.

    2015-01-01

    The transcription factor, signal transducer and activator of transcription 3 (STAT3), has been implicated in protecting the heart from acute ischemic injury under both basal conditions and as a crucial component of pre- and post-conditioning protocols. A number of anti-oxidant and antiapoptotic genes are upregulated by STAT3 via canonical means involving phosphorylation on Y705 and S727, although other incompletely defined posttranslational modifications are involved. In addition, STAT3 is now known to be present in cardiac mitochondria and to exert actions that regulate the electron transport chain, reactive oxygen species production, and mitochondrial permeability transition pore opening. These non-canonical actions of STAT3 are enhanced by S727 phosphorylation. The molecular basis for the mitochondrial actions of STAT3 is poorly understood, but STAT3 is known to interact with a critical subunit of complex I and to regulate complex I function. Dysfunctional complex I has been implicated in ischemic injury, heart failure, and the aging process. Evidence also indicates that STAT3 is protective to the heart under chronic stress conditions, including hypertension, pregnancy, and advanced age. Paradoxically, the accumulation of unphosphorylated STAT3 (U-STAT3) in the nucleus has been suggested to drive pathological cardiac hypertrophy and inflammation via non-canonical gene expression, perhaps involving a distinct acetylation profile. U-STAT3 may also regulate chromatin stability. Our understanding of how the non-canonical genomic and mitochondrial actions of STAT3 in the heart are regulated and coordinated with the canonical actions of STAT3 is rudimentary. Here, we present an overview of what is currently known about the pleotropic actions of STAT3 in the heart in order to highlight controversies and unresolved issues. PMID:26664907

  16. Effective Organizational Structures and Processes: Addressing Issues of Change

    ERIC Educational Resources Information Center

    Andrade, Maureen Snow

    2016-01-01

    This chapter describes organizational structures and processes at the institutional and project levels for the development and support of distance learning initiatives. It addresses environmental and stakeholder issues and explores principles and strategies of effective leadership for change creation and management.

  17. Family Connections: Addressing Behavior Issues--Practical Tips for Parents

    ERIC Educational Resources Information Center

    LaCaze, Donna; Kirylo, James D.

    2012-01-01

    When parents get together, the subject of appropriately addressing the behavior of their children often comes to the forefront of conversations. Parents share various challenges they face with their children, including issues associated with listening, eating vegetables, doing chores, and a host of other discipline-related situations. The plethora…

  18. Addressing Consent Issues in Donation After Circulatory Determination of Death.

    PubMed

    Overby, Kim J; Weinstein, Michael S; Fiester, Autumn

    2015-01-01

    Given the widening gap between the number of individuals on transplant waiting lists and the availability of donated organs, as well as the recent plateau in donations based on neurological criteria (i.e., brain death), there has been a growing interest in expanding donation after circulatory determination of death. While the prevalence of this form of organ donation continues to increase, many thorny ethical issues remain, often creating moral distress in both clinicians and families. In this article, we address one of these issues, namely, the challenges surrounding patient and surrogate informed consent for donation after circulatory determination of death. First we discuss several general concerns regarding consent related to this form of organ donation, and then we address additional issues that are unique to three different patient categories: adult patients with medical decision-making capacity or potential capacity, adult patients who lack capacity, and pediatric patients.

  19. Recent NRC research activities addressing valve and pump issues

    SciTech Connect

    Morrison, D.L.

    1996-12-01

    The mission of the U.S. Nuclear Regulatory Commission (NRC) is to ensure the safe design, construction, and operation of commercial nuclear power plants and other facilities in the U.S.A. One of the main roles that the Office of Nuclear Regulatory Research (RES) plays in achieving the NRC mission is to plan, recommend, and implement research programs that address safety and technical issues deemed important by the NRC. The results of the research activities provide the bases for developing NRC positions or decisions on these issues. Also, RES performs confirmatory research for developing the basis to evaluate industry responses and positions on various regulatory requirements. This presentation summarizes some recent RES supported research activities that have addressed safety and technical issues related to valves and pumps. These activities include the efforts on determining valve and motor-operator responses under dynamic loads and pressure locking events, evaluation of monitoring equipment, and methods for detecting and trending aging of check valves and pumps. The role that RES is expected to play in future years to fulfill the NRC mission is also discussed.

  20. Seizures induced by frustration and despair due to unresolved moral and political issues: a rare case of reflex epilepsy.

    PubMed

    Cohen, O; River, Y; Abramsky, O

    1999-01-01

    We present a case of reflex-induced simple partial seizures, triggered by feelings of frustration, anger and despair. Such emotions were provoked by pondering over complex national and international, political and moral issues. The present case may suggest that activation of right temporal networks may mediate negative and adverse emotions induced by preoccupation with agitating, controversial issues.

  1. Western Wind Strategy: Addressing Critical Issues for Wind Deployment

    SciTech Connect

    Douglas Larson; Thomas Carr

    2012-03-30

    The goal of the Western Wind Strategy project was to help remove critical barriers to wind development in the Western Interconnection. The four stated objectives of this project were to: (1) identify the barriers, particularly barriers to the operational integration of renewables and barriers identified by load-serving entities (LSEs) that will be buying wind generation, (2) communicate the barriers to state officials, (3) create a collaborative process to address those barriers with the Western states, utilities and the renewable industry, and (4) provide a role model for other regions. The project has been on the forefront of identifying and informing state policy makers and utility regulators of critical issues related to wind energy and the integration of variable generation. The project has been a critical component in the efforts of states to push forward important reforms and innovations that will enable states to meet their renewable energy goals and lower the cost to consumers of integrating variable generation.

  2. Physical forcing and physical/biochemical variability of the Mediterranean Sea: a review of unresolved issues and directions for future research

    NASA Astrophysics Data System (ADS)

    Malanotte-Rizzoli, P.; Artale, V.; Borzelli-Eusebi, G. L.; Brenner, S.; Civitarese, G.; Crise, A.; Font, J.; Gacic, M.; Kress, N.; Marullo, S.; Ozsoy, E.; Ribera d'Alcalà, M.; Roether, W.; Schroeder, K.; Sofianos, S.; Tanhua, T.; Theocharis, A.; Alvarez, M.; Ashkenazy, Y.; Bergamasco, A.; Cardin, V.; Carniel, S.; D'Ortenzio, F.; Garcia-Ladona, E.; Garcia-Lafuente, J. M.; Gogou, A.; Gregoire, M.; Hainbucher, D.; Kontoyannis, H.; Kovacevic, V.; Krasakapoulou, E.; Krokos, G.; Incarbona, A.; Mazzocchi, M. G.; Orlic, M.; Pascual, A.; Poulain, P.-M.; Rubino, A.; Siokou-Frangou, J.; Souvermezoglou, E.; Sprovieri, M.; Taupier-Letage, I.; Tintoré, J.; Triantafyllou, G.

    2013-07-01

    convection cells are much more amenable to direct observational surveys and mooring arrays. An ubiquitous, energetic mesoscale and sub-mesoscale eddy field is superimposed to and interacts with the sub-basin scale, wind-driven gyres that characterize the upper thermocline circulation. Three different scales of motion are therefore superimposed producing a richness of interaction processes which typify similar interactions in unexplored ocean regions. Both wide and narrow shelves are present separated by steep continental slopes from the deep interiors. Cross-shelf fluxes of physical as well biogeochemical parameters are crucial in determining the properties of the shallow versus deep local ecosystems and their trophic chain. Most importantly, the Mediterranean Sea is a basin of contrasting ecosystems, from the strongly oligotrophic deep interiors to the fully eutrophic northern Adriatic characterized by recurrent, anomalous algal blooms and related anoxia events. This review focuses on the identification of the major unresolved scientific issues and wants also to provide directions for future research which may lead to the formulation of interdisciplinary, collaborative implementation plans to address these issues both theoretically and observationally.

  3. Addressing security issues related to virtual institute distributed activities

    NASA Astrophysics Data System (ADS)

    Stytz, Martin R.; Banks, Sheila B.

    2008-03-01

    One issue confounding the development and experimentation of distributed modeling and simulation environments is the inability of the project team to identify and collaborate with resources, both human and technical, from outside the United States. This limitation is especially significant within the human behavior representation area where areas such as cultural effects research and joint command team behavior modeling require the participation of various cultural and national representatives. To address this limitation, as well as other human behavior representation research issues, NATO Research and Technology Organization initiated a project to develop a NATO virtual institute that enables more effective and more collaborative research into human behavior representation. However, in building and operating a virtual institute one of the chief concerns must be the cyber security of the institute. Because the institute "exists" in cyberspace, all of its activities are susceptible to cyberattacks, subterfuge, denial of service and all of the vulnerabilities that networked computers must face. In our opinion, for the concept of virtual institutes to be successful and useful, their operations and services must be protected from the threats in the cyber environment. A key to developing the required protection is the development and promulgation of standards for cyber security. In this paper, we discuss the types of cyber standards that are required, how new internet technologies can be exploited and can benefit the promulgation, development, maintenance, and robustness of the standards. This paper is organized as follows. Section One introduces the concept of the virtual institutes, the expected benefits, and the motivation for our research and for research in this area. Section Two presents background material and a discussion of topics related to VIs, uman behavior and cultural modeling, and network-centric warfare. Section Three contains a discussion of the

  4. Distributed photovoltaic systems - Addressing the utility interface issues

    NASA Astrophysics Data System (ADS)

    Firstman, S. I.; Vachtsevanos, G. J.

    This paper reviews work conducted in the United States on the impact of dispersed photovoltaic sources upon utility operations. The photovoltaic (PV) arrays are roof-mounted on residential houses and connected, via appropriate power conditioning equipment, to the utility grid. The presence of such small (4-6 Kw) dispersed generators on the distribution network raises questions of a technical, economic and institutional nature. After a brief identification of utility interface issues, the paper addresses such technical concerns as protection of equipment and personnel safety, power quality and utility operational stability. A combination of experimental and analytical approaches has been adopted to arrive at solutions to these problems. Problem areas, under various PV system penetration scenarios, are identified and conceptual designs of protection and control equipment and operating policies are developed so that system reliability is maintained while minimizing capital costs. It is hoped that the resolution of balance-of-system and grid interface questions will ascertain the economic viability of photovoltaic systems and assist in their widespread utilization in the future.

  5. The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions.

    PubMed

    Sfikakis, Petros P

    2010-01-01

    Results from clinical trials of biologic anti-TNF drugs performed in the late 1990s confirmed the biological relevance of TNF function in the pathogenesis of chronic noninfectious inflammation of joints, skin and gut, which collectively affects 2-3% of the population. Up to April 2009, more than two million patients worldwide have received the first marketed drugs, namely the monoclonal anti-TNF antibodies infliximab and adalimumab and the soluble TNF receptor etanercept. All three are equally effective in rheumatoid arthritis, ankylosing spondylitis, psoriasis and psoriatic arthritis, but, for not clearly defined reasons, only the monoclonal antibodies are effective in inflammatory bowel disease. About 60% of patients who do not benefit from standard nonbiologic treatments for these diseases respond to TNF antagonists. Less than half of responding patients achieve complete remission of disease. Importantly, some of those patients with rheumatoid arthritis in whom long-term anti-TNF therapy induced disease remission remain disease-free after discontinuation of any kind of treatment. There are not yet reliable predictors of which patients will or will not respond on anti-TNF therapy, whereas subsequent loss of an initial clinical response occurs frequently. The spectrum of efficacy anti-TNF therapies widens to include diseases such as systemic vasculitis and sight-threatening uveitis. While paradoxical new adverse effects are recognized, i.e. exacerbation or development of new onset psoriasis, reactivation of latent tuberculosis remains the most important safety issue of anti-TNF therapies. Clinical practice guidelines and consensus statements on the criteria of introduction, duration of treatment and cessation of TNF antagonists, including safety issues, are under constant revision as data from longer periods of patient exposure accumulate. It is hoped that more efficacious drugs that will ideally target the deleterious proinflammatory properties of TNF without

  6. Unresolved issues in hematopoietic stem cell transplantation for severe combined immunodeficiency: need for safer conditioning and reduced late effects.

    PubMed

    Horn, Biljana; Cowan, Morton J

    2013-05-01

    In this review we discuss recent outcomes of hematopoietic cell transplantation (HCT) for patients with severe combined immunodeficiency (SCID), including survival, T- and B-cell reconstitution, and late effects, particularly those related to genotype, use of conditioning regimen, and use of alternative donors. We identify the following issues that require additional data, which can be obtained through cooperative studies: outcomes of patients with SCID who did not receive conditioning before alternative donor HCT; outcomes of patients with SCID who did not receive graft-versus-host disease prophylaxis after T cell-replete HCT; late effects of HCT for patients with SCID, including neurocognitive outcomes, growth, and development; and their relationship to genotype and use of alkylating agents for conditioning. Careful follow-up of outcomes of all newborns receiving diagnoses based on newborn screening programs for SCID is essential because data are scarce on the effects of conditioning regimens in very young patients. A consensus on the definition of T- and B-cell recovery, criteria for additional "boosts," pharmacokinetic data of chemotherapy agents used in young children, and uniformity of the use of various chemotherapy agents are needed to compare results among institutions. Finally, development of new nontoxic conditioning regimens for HCT that can be safely used in very young children is required.

  7. Position statement--altitude training for improving team-sport players' performance: current knowledge and unresolved issues.

    PubMed

    Girard, Olivier; Amann, Markus; Aughey, Robert; Billaut, François; Bishop, David J; Bourdon, Pitre; Buchheit, Martin; Chapman, Robert; D'Hooghe, Michel; Garvican-Lewis, Laura A; Gore, Christopher J; Millet, Grégoire P; Roach, Gregory D; Sargent, Charli; Saunders, Philo U; Schmidt, Walter; Schumacher, Yorck O

    2013-12-01

    Despite the limited research on the effects of altitude (or hypoxic) training interventions on team-sport performance, players from all around the world engaged in these sports are now using altitude training more than ever before. In March 2013, an Altitude Training and Team Sports conference was held in Doha, Qatar, to establish a forum of research and practical insights into this rapidly growing field. A round-table meeting in which the panellists engaged in focused discussions concluded this conference. This has resulted in the present position statement, designed to highlight some key issues raised during the debates and to integrate the ideas into a shared conceptual framework. The present signposting document has been developed for use by support teams (coaches, performance scientists, physicians, strength and conditioning staff) and other professionals who have an interest in the practical application of altitude training for team sports. After more than four decades of research, there is still no consensus on the optimal strategies to elicit the best results from altitude training in a team-sport population. However, there are some recommended strategies discussed in this position statement to adopt for improving the acclimatisation process when training/competing at altitude and for potentially enhancing sea-level performance. It is our hope that this information will be intriguing, balanced and, more importantly, stimulating to the point that it promotes constructive discussion and serves as a guide for future research aimed at advancing the bourgeoning body of knowledge in the area of altitude training for team sports.

  8. Addressing Teachers' Feelings of Lack of Control over Policy Issues

    ERIC Educational Resources Information Center

    Judson, Eugene

    2014-01-01

    This study reports on how an American Education System course, traditionally taught with broad objectives, was contextualized for science teachers. Using pre-assessment data, specific policy issues were targeted with the objective of increasing teachers' feelings of influence over issues. The approach used was adapted from exposure therapy, a…

  9. Cost Issues Unresolved in Chicago

    ERIC Educational Resources Information Center

    Sawchuk, Stephen

    2012-01-01

    Chicago teachers voted last week to suspend a 7-day-old strike, sending some 350,000 students back to the classroom and paving the way for the teaching force to vote on a tentative contract. But for many in the Windy City, the contract has raised another potentially tall hurdle: how the cash-strapped district will manage to pay for it. District…

  10. Addressing the human factors issues associated with control room modifications

    SciTech Connect

    O`Hara, J.; Stubler, W.; Kramer, J.

    1998-03-01

    Advanced human-system interface (HSI) technology is being integrated into existing nuclear plants as part of plant modifications and upgrades. The result of this trend is that hybrid HSIs are created, i.e., HSIs containing a mixture of conventional (analog) and advanced (digital) technology. The purpose of the present research is to define the potential effects of hybrid HSIs on personnel performance and plant safety and to develop human factors guidance for safety reviews of them where necessary. In support of this objective, human factors issues associated with hybrid HSIs were identified. The issues were evaluated for their potential significance to plant safety, i.e., their human performance concerns have the potential to compromise plant safety. The issues were then prioritized and a subset was selected for design review guidance development.

  11. Teaching Writing in a Digital Age: Addressing Issues of Access

    ERIC Educational Resources Information Center

    Cottrill, Brittany B.

    2010-01-01

    The way people write and communicate has changed both inside and outside the university, and because of this writing instructors are professionally responsible for addressing these changes in the classroom. Technologies have affected writing for thousands of years. From the invention of the printing press to the Internet, challenges to writing…

  12. Imaginative Thinking: Addressing Social Justice Issues through MovieMaker

    ERIC Educational Resources Information Center

    Boske, Christa A.

    2009-01-01

    Purpose: The purpose of this paper is to examine the experiences of aspiring school leaders who utilized artmaking in this case, photography, poetry, music, collage, and short films through Microsoft MovieMaker as a means for addressing injustices within surrounding school communities. The paper aims to explore how aspiring school leaders…

  13. Teaching for Diversity: Addressing Diversity Issues in Responsive ESL Instruction

    ERIC Educational Resources Information Center

    Fu, Jing

    2013-01-01

    Student diversity has become a typical phenomenon in American public schools. The impact of increasing diversity on literacy instruction is unchallenged. Teachers reinforce this message by often citing ESL student diversity as a barrier for literacy teaching. In order to better understand the complexity of diversity issues, I explored two ESL…

  14. Legal Considerations of Internet Use--Issues To Be Addressed.

    ERIC Educational Resources Information Center

    Thomas, Daphyne Saunders; Forcht, Karen A.; Counts, Peter

    1998-01-01

    Explores issues related to legal considerations of the widespread use of the Internet worldwide. Topics considered include: e-mail; data theft and piracy; search and seizure; electronic banking; offensive behavior; liability; copyright infringement; laws regulating the Internet; and the Telecommunications Act. (PEN)

  15. Creating Art Environments That Address Social Justice Issues

    ERIC Educational Resources Information Center

    Tremblay, Gail

    2013-01-01

    In this article, I examine strategies for teaching students to make socially conscious art using a variety of media that emphasizes installation work. I present issues of social justice in the contemporary art world and include concerns of censorship that artists sometimes confront. I offer examples of team taught coordinated studies programs…

  16. Adolescent Social Issues: Using Media to Address Crucial Concerns.

    ERIC Educational Resources Information Center

    Sokoloff, Michele

    1987-01-01

    This article describes media resources available to help adolescents deal with a variety of social concerns, including substance abuse, dropouts, Acquired Immune Deficiency Syndrome (AIDS), suicide, and pregnancy. A list of 56 companies that provide resources dealing with social issues is also provided. (LRW)

  17. Plan for addressing issues relating to oil shale plant siting

    SciTech Connect

    Noridin, J. S.; Donovan, R.; Trudell, L.; Dean, J.; Blevins, A.; Harrington, L. W.; James, R.; Berdan, G.

    1987-09-01

    The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research needs. 910 refs., 3 figs., 30 tabs.

  18. Reservoir technology research at LBL addressing geysers issues

    SciTech Connect

    Lippmann, M.J.; Bodvarsson, G.S.

    1990-04-01

    The Geothermal Technology Division of the Department of Energy is redirecting a significant part of its Reservoir Technology funding to study problems now being experienced at The Geysers. These include excessive pressure drawdown and associated decline in well flow rates, corrosion due to high chloride concentration in the produced steam and high concentration of noncondensible gases in some parts of the field. Lawrence Berkeley Laboratory (LBL) is addressing some of these problems through field, laboratory and theoretical studies. 11 refs., 6 figs.

  19. Addressing Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ) Issues in Teacher Education: Teacher Candidates' Perceptions

    ERIC Educational Resources Information Center

    Kitchen, Julian; Bellini, Christine

    2012-01-01

    Homophobic harassment and bullying are persistent issues in Canadian schools despite recent initiatives to improve school climate. Among the reasons is that educators feel reluctant or ill-prepared to address these issues. The purpose of this paper is to examine how teacher education can help make schools safer by addressing LGBTQ issues and…

  20. A mental model proposed to address sustainability and terrorism issues.

    PubMed

    Schwing, Richard

    2002-06-01

    I have assembled traditional ways to think about human needs and power along with empirical data to support a mental model of human values. The hierarchy of needs from the world of psychology and the hierarchy of power from the world of diplomacy provide a structure for the model. The empirical data collected from several nations over the last three decades support the structure. Furthermore, an examination of specific trends in this data for specific values indicates that it is not impossible to achieve a sustainable world driven by sustainable values. A world that will be defined by its successful movement toward the "triple bottom line," a term articulated by John Elkington, is a world in which economic prosperity, environmental protection, and social equity are aligned. To say that the model allows one to address terrorism is based on the assumption that the lack of social equity or the perception of that lack determines the likelihood of terrorism.

  1. Addressing psychosocial issues in cancer survivorship: past, present and future.

    PubMed

    Walsh, Katherine

    2016-12-01

    With a burgeoning population of cancer survivors, organizations in the USA and around the world are considering how to address the many long-term and late psychosocial effects of cancer and cancer treatment. This article reviews the changing landscape of survivorship care over the past 50 years, from the time when there were relatively few survivors to the future, when the number of cancer survivors in the USA alone is expected to reach close to 20 million. Institute of Medicine Reports, intra-organizational summits and accrediting standards that have influenced the development of survivorship care plans and programs and the roles of the Internet and smartphone applications along with oncology specialist and primary care providers are discussed.

  2. Use of feedback control to address flight safety issues

    NASA Astrophysics Data System (ADS)

    Ganguli, Subhabrata

    This thesis addresses three control problems related to flight safety. The first problem relates to the scope of improvement in performance of conventional flight control laws. In particular, aircraft longitudinal axis control based on the Total Energy Control System (TECS) is studied. The research draws attention to a potentially sluggish and undesirable aircraft response when the engine dynamics is slow (typically the case). The proposed design method uses a theoretically well-developed modern design method based on Hinfinity optimization to improve the aircraft dynamic behavior in spite of slow engine characteristics. At the same time, the proposed design method achieves other desirable performance goals such as insensitivity to sensor noise and wind gust rejection: all addressed in one unified framework. The second problem is based on a system level analysis of control structure hierarchy for aircraft flight control. The objective of the analysis problem is to translate outer-loop stability and performance specifications into a comprehensive inner-loop metric. The prime motivation is to make the flight control design process more systematic and the system-integration reliable and independent of design methodology. The analysis problem is posed within the robust control analysis framework. Structured singular value techniques and free controller parameterization ideas are used to impose a hierarchical structure for flight control architecture. The third problem involves development and demonstration of a new reconfiguration strategy in the flight control architecture that has the potential of improving flight safety while keeping cost and complexity low. This research proposes a fault tolerant feature based on active robust reconfiguration. The fault tolerant control problem is formulated in the Linear Parameter Varying (LPV) design framework. A prime advantage of this approach is that the synthesis results in a single nonlinear controller (as opposed to a bank

  3. Developing integrated methods to address complex resource and environmental issues

    USGS Publications Warehouse

    Smith, Kathleen S.; Phillips, Jeffrey D.; McCafferty, Anne E.; Clark, Roger N.

    2016-02-08

    IntroductionThis circular provides an overview of selected activities that were conducted within the U.S. Geological Survey (USGS) Integrated Methods Development Project, an interdisciplinary project designed to develop new tools and conduct innovative research requiring integration of geologic, geophysical, geochemical, and remote-sensing expertise. The project was supported by the USGS Mineral Resources Program, and its products and acquired capabilities have broad applications to missions throughout the USGS and beyond.In addressing challenges associated with understanding the location, quantity, and quality of mineral resources, and in investigating the potential environmental consequences of resource development, a number of field and laboratory capabilities and interpretative methodologies evolved from the project that have applications to traditional resource studies as well as to studies related to ecosystem health, human health, disaster and hazard assessment, and planetary science. New or improved tools and research findings developed within the project have been applied to other projects and activities. Specifically, geophysical equipment and techniques have been applied to a variety of traditional and nontraditional mineral- and energy-resource studies, military applications, environmental investigations, and applied research activities that involve climate change, mapping techniques, and monitoring capabilities. Diverse applied geochemistry activities provide a process-level understanding of the mobility, chemical speciation, and bioavailability of elements, particularly metals and metalloids, in a variety of environmental settings. Imaging spectroscopy capabilities maintained and developed within the project have been applied to traditional resource studies as well as to studies related to ecosystem health, human health, disaster assessment, and planetary science. Brief descriptions of capabilities and laboratory facilities and summaries of some

  4. Issue-Specific Barriers to Addressing Environmental Issues in the Classroom: An Exploratory Study

    ERIC Educational Resources Information Center

    Kim, Chankook; Fortner, Rosanne W.

    2006-01-01

    To explore issue-specific barriers to teaching environmental issues, the authors investigated secondary science teachers' perceived current and preferred teaching levels for 23 environmental issues and perceived barriers to teaching the selected issues. Subjects in this graduate project were 41 secondary science teachers self-selected to answer a…

  5. Identification of a senior superfund official for addressing special npl site-related issues. Directive

    SciTech Connect

    Not Available

    1992-05-22

    The directive identifies a senior Superfund official responsible for reviewing and addressing specific issues at NPL (National Priorities List) sites that cannot be resolved at the Regional level and identifies criteria for NPL site referrals to this official.

  6. Addressing Individual Difficulties in Reading: Issues Relating to Reading Recovery and Pause, Prompt, Praise

    ERIC Educational Resources Information Center

    Wearmouth, Janice

    2004-01-01

    Recently the DfES has issued guidance on ways to address the needs of students who experience difficulties in literacy through Wave Three provision in the National Literacy Strategy (DfES, 2002). This guidance raises the issue of what kind of programmes might be initiated in mainstream schools that will improve what is available generally for…

  7. 49 CFR 192.933 - What actions must be taken to address integrity issues?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Transmission Pipeline Integrity Management § 192.933 What actions must be taken to address integrity issues? (a... issues? 192.933 Section 192.933 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED)...

  8. The evolving role of partnerships in addressing community public health issues: policy and ethical implications.

    PubMed

    Wendel, Monica L; Burdine, James N; McLeroy, Kenneth R

    2007-01-01

    The current state of health insurance coverage in the United States is deteriorating. Historically, efforts to address access at the federal level have met with insurmountable opposition. This article describes a model utilizing the Partnership Approach to Community Health Improvement to engage communities in developing creative ways of addressing local health issues, discusses the policy implications of such a model, and explores ethical issues inherent in the discussion of universal access. An argument is presented for a national dialogue seeking societal agreement to approach access and health from a perspective of solidarity.

  9. Addressing Issues of Religious Difference through Values Education: An Islam Instance

    ERIC Educational Resources Information Center

    Lovat, Terence; Clement, Neville; Dally, Kerry; Toomey, Ron

    2010-01-01

    The article's main focus is on exploring ways in which modern forms of values education are being utilized to address major issues of social dissonance, with special focus on dissonance related to religious difference between students of Islamic and non-Islamic backgrounds. The article begins by appraising philosophical and neuroscientific…

  10. The Importance of Exposure in Addressing Current and Emerging Air Quality Issues

    EPA Science Inventory

    The air quality issues that we face today and will face in the future are becoming increasingly more complex and require an improved understanding of human exposure to be effectively addressed. The objectives of this paper are (1) to discuss how concepts of human exposure and ex...

  11. Identification of a senior Superfund official for addressing special NPL site-related issues. Directive

    SciTech Connect

    Not Available

    1992-05-22

    The directive describes the process for identifying a senior Superfund official responsible for reviewing and addressing specific issues at National Priorities List sites that cannot be resolved at the Regional level, and for identifying criteria for NPL site referrals to this official.

  12. 23 CFR 636.501 - What issues may be addressed in discussions?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false What issues may be addressed in discussions? 636.501 Section 636.501 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Discussions, Proposal Revisions and Source Selection §...

  13. Race and Science: Using a Comprehensive Interdisciplinary Approach To Address Complex Issues.

    ERIC Educational Resources Information Center

    Eisen, Arri; Cimino, Ashley; Aparicio, Hugo; Marsteller, Patricia; Kushner, Howard

    2003-01-01

    Describes an interdisciplinary approach that integrates the strengths of a research and teaching institution to address issues in a complex problem: the study of race, science, and health. The model involved a feedback loop among two undergraduate courses and a weekly seminar. (SLD)

  14. From Professional Development to Classroom Instruction: Addressing Issues Related to Science Inquiry Discourse

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.

    2009-01-01

    In this rejoinder, I first provide a more detailed account of the discourse-focused professional development activities facilitated as part of the SMIT'N program, specifically addressing issues raised by van Zee with regard to the institute's overall format, goals and development strategies. Next, I resort to Peter Medawar's metaphorical view of…

  15. Addressing the shortage of health professionals in rural China: issues and progress

    PubMed Central

    Hou, Jianlin; Ke, Yang

    2015-01-01

    Maldistribution of health professionals between urban and rural areas has been a serious problem in China. Urban hospitals attract most of the health professionals with serious shortages in rural areas. To address this issue, a number of policies have been implemented by the government, such as free medical education in exchange for obligatory rural service. PMID:25905487

  16. Beyond the Dialectics and Polemics: Canadian Catholic Schools Addressing LGBT Youth Issues

    ERIC Educational Resources Information Center

    Liboro, Renato M.; Travers, Robb; St. John, Alex

    2015-01-01

    In 2012, Canadian media coverage on Bill 13--an Ontario legislative proposal to require all publicly funded schools to support Gay-Straight Alliances as a means of addressing issues concerning bullied lesbian, gay, bisexual, and transgender (LGBT) students--instigated a divisive exchange among representatives of the Ontario Catholic school sector.…

  17. Web-Based Geospatial Tools to Address Hazard Mitigation, Natural Resource Management, and Other Societal Issues

    USGS Publications Warehouse

    Hearn,, Paul P.

    2009-01-01

    Federal, State, and local government agencies in the United States face a broad range of issues on a daily basis. Among these are natural hazard mitigation, homeland security, emergency response, economic and community development, water supply, and health and safety services. The U.S. Geological Survey (USGS) helps decision makers address these issues by providing natural hazard assessments, information on energy, mineral, water and biological resources, maps, and other geospatial information. Increasingly, decision makers at all levels are challenged not by the lack of information, but by the absence of effective tools to synthesize the large volume of data available, and to utilize the data to frame policy options in a straightforward and understandable manner. While geographic information system (GIS) technology has been widely applied to this end, systems with the necessary analytical power have been usable only by trained operators. The USGS is addressing the need for more accessible, manageable data tools by developing a suite of Web-based geospatial applications that will incorporate USGS and cooperating partner data into the decision making process for a variety of critical issues. Examples of Web-based geospatial tools being used to address societal issues follow.

  18. The role of Violence Against Women Act in addressing intimate partner violence: a public health issue.

    PubMed

    Modi, Monica N; Palmer, Sheallah; Armstrong, Alicia

    2014-03-01

    Intimate partner violence (IPV) is defined as violence committed by a current or former boyfriend or girlfriend, spouse or ex-spouse. Each year, 1.3 to 5.3 million women in the United States experience IPV. The large number of individuals affected, the enormous healthcare costs, and the need for a multidisciplinary approach make IPV an important healthcare issue. The Violence Against Women Act (VAWA) addresses domestic violence, dating violence, sexual assault, and stalking. It emphasizes development of coordinated community care among law enforcement, prosecutors, victim services, and attorneys. VAWA was not reauthorized in 2012 because it lacked bipartisan support. VAWA 2013 contains much needed new provisions for Native Americans; lesbian, gay, bisexual, transgender, gay, and queer (LGBTQ) individuals; and victims of human trafficking but does not address the large amount of intimate partner violence in America's immigrant population. There are important remaining issues regarding intimate partner violence that need to be addressed by future legislation. This review examines the role of legislation and addresses proposals for helping victims of IPV.

  19. Science Teachers' Use of Mass Media to Address Socio-Scientific and Sustainability Issues

    NASA Astrophysics Data System (ADS)

    Klosterman, Michelle L.; Sadler, Troy D.; Brown, Julie

    2012-01-01

    The currency, relevancy and changing nature of science makes it a natural topic of focus for mass media outlets. Science teachers and students can capitalize on this wealth of scientific information to explore socio-scientific and sustainability issues; however, without a lens on how those media are created and how representations of science are constructed through media, the use of mass media in the science classroom may be risky. Limited research has explored how science teachers naturally use mass media to explore scientific issues in the classroom or how mass media is used to address potential overlaps between socio-scientific-issue based instruction and education for sustainability. This naturalistic study investigated the reported and actual classroom uses of mass media by secondary science teachers' to explore socio-scientific and sustainability issues as well as the extent to which their instructional approaches did or did not overlap with frameworks for SSI-based instruction, education for sustainability, and media literacy education. The results of this study suggest that secondary science teachers use mass media to explore socio-scientific and sustainability issues, but their use of frameworks aligned with SSI-based, education for sustainability, and media literacy education was limited. This paper provides suggestions for how we, as science educators and researchers, can advance a teaching and learning agenda for encouraging instruction that more fully utilizes the potential of mass media to explore socio-scientific issues in line with perspectives from education for sustainability.

  20. 76 FR 58846 - Final Interim Staff Guidance: Review of Evaluation To Address Gas Accumulation Issues in Safety...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Final Interim Staff Guidance: Review of Evaluation To Address Gas Accumulation Issues in Safety.... Nuclear Regulatory Commission (NRC) staff is issuing its Final Interim Staff Guidance (ISG)...

  1. State of the Art, Unresolved Issues, and Future Research Directions in the Fight against Hepatitis C Virus: Perspectives for Screening, Diagnostics of Resistances, and Immunization

    PubMed Central

    Ansaldi, Filippo

    2016-01-01

    Hepatitis C virus (HCV) still represents a major public health threat, with a dramatic burden from both epidemiological and clinical points of view. New generation of direct-acting antiviral agents (DAAs) has been recently introduced in clinical practice promising to cure HCV and to overcome the issues related to the interferon-based therapies. However, the emergence of drug resistance and the suboptimal activity of DAAs therapies against diverse HCV genotypes have been observed, determining treatment failure and hampering an effective control of HCV spread worldwide. Moreover, these treatments remain poorly accessible, particularly in low-income countries. Finally, effective screening strategy is crucial to early identifying and treating all HCV chronically infected patients. For all these reasons, even though new drugs may contribute to impacting HCV spread worldwide a preventive HCV vaccine remains a cornerstone in the road to significantly reduce the HCV spread globally, with the ultimate goal of its eradication. Advances in molecular vaccinology, together with a strong financial, political, and societal support, will enable reaching this fundamental success in the coming years. In this comprehensive review, the state of the art about these major topics in the fight against HCV and the future of research in these fields are discussed. PMID:27843956

  2. Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program.

    PubMed

    Odin, P; Ray Chaudhuri, K; Slevin, J T; Volkmann, J; Dietrichs, E; Martinez-Martin, P; Krauss, J K; Henriksen, T; Katzenschlager, R; Antonini, A; Rascol, O; Poewe, W

    2015-10-01

    Navigate PD was an educational program established to supplement existing guidelines and provide recommendations on the management of Parkinson's disease (PD) refractory to oral/transdermal therapies. It involved 103 experts from 13 countries overseen by an International Steering Committee (ISC) of 13 movement disorder specialists. The ISC identified 71 clinical questions important for device-aided management of PD. Fifty-six experts responded to a web-based survey, rating 15 questions as 'critically important;' these were refined to 10 questions by the ISC to be addressed through available evidence and expert opinion. Draft guidance was presented at international/national meetings and revised based on feedback. Key take-home points are: • Patients requiring levodopa >5 times daily who have severe, troublesome 'off' periods (>1-2 h/day) despite optimal oral/transdermal levodopa or non-levodopa-based therapies should be referred for specialist assessment even if disease duration is <4 years. • Cognitive decline related to non-motor fluctuations is an indication for device-aided therapies. If cognitive impairment is mild, use deep brain stimulation (DBS) with caution. For patients who have cognitive impairment or dementia, intrajejunal levodopa infusion is considered as both therapeutic and palliative in some countries. Falls are linked to cognitive decline and are likely to become more frequent with device-aided therapies. • Insufficient control of motor complications (or drug-resistant tremor in the case of DBS) are indications for device-aided therapies. Levodopa-carbidopa intestinal gel infusions or subcutaneous apomorphine pump may be considered for patients aged >70 years who have mild or moderate cognitive impairment, severe depression or other contraindications to DBS.

  3. The Main Issues to Address in Modeling Plasma Spray Torch Operation

    NASA Astrophysics Data System (ADS)

    Chazelas, C.; Trelles, J. P.; Vardelle, A.

    2017-01-01

    The modeling of plasma torch operation has advanced greatly in the last 15 years due to a better understanding of the underlying physics, development of commercial, open-source computational fluid dynamics softwares, and access to high performance and cloud computing. However, the operation mode of the electric arc in plasma torches is controlled by dynamic, thermal, electromagnetic, acoustic and chemical phenomena that take place at different scales and whose interactions are not completely understood yet. Even though no single model of plasma torch operation fully addresses these phenomena, most of these models are useful tools for parametric studies, if their use is reinforced by knowledge of torch operation and the model predictions are validated against experimental data. To increase the level of predictability of the current models, several further steps are needed. This study examines the issues remaining to be addressed in the modeling of plasma spray torch operation and the current critical aspects of these.

  4. Commentary: what role should physician organizations play in addressing social justice issues?

    PubMed

    Bright, Cedric M

    2012-06-01

    A study by Peek and colleagues in this issue reveals that although racial and ethnic health disparities are recognized as a major national challenge, few physician organizations with both the influence and ability to change practice standards and address disparities appear to be effectively directing their resources to mitigate health disparities. In this commentary, the author examines the history of U.S. health disparities through the lens of social justice. He argues that today, physician organizations have the opportunity to change the paradigm of medicine from being a reactive industry to becoming a proactive industry through collaborations such as the Commission to End Health Disparities, which brings together more than 60 organizations, and the National Medical Association's "We Stand With You" program to improve health and combat disparities. Physician organizations can also address health disparities through advocacy for fair reimbursement policies, funding for pipeline programs to increase the diversity of the workforce, diversity in clinical trials, and other issues. Health disparities present to us in organized medicine a challenge that is cleverly disguised as an immovable object but that is truly a great opportunity for innovation, improvement, and growth. Physician organizations have a unique opportunity to provide avenues of innovation and accomplishment.

  5. Identifying the mathematics middle year students use as they address a community issue

    NASA Astrophysics Data System (ADS)

    Marshman, Margaret

    2017-03-01

    Middle year students often do not see the mathematics in the real world whereas the Australian Curriculum: Mathematics aims for students to be "confident and creative users and communicators of mathematics" (Australian Curriculum Assessment and Reporting Authority [ACARA] 2012). Using authentic and real mathematics tasks can address this situation. This paper is an account of how, working within a Knowledge Producing Schools' framework, a group of middle year students addressed a real community issue, the problem of the lack of a teenage safe space using mathematics and technology. Data were collected for this case study via journal observations and reflections, semi-structured interviews, samples of the students' work and videos of students working. The data were analysed by identifying the mathematics the students used determining the function and location of the space and focused on problem negotiation, formulation and solving through the statistical investigation cycle. The paper will identify the mathematics and statistics these students used as they addressed a real problem in their local community.

  6. The corporate impact of addressing social issues: a financial case study of a project in Peru.

    PubMed

    Dabbs, Alan; Bateson, Matthew

    2002-05-01

    Large, multinational resource development projects can affect many aspects, including social, economic and ecological realities, in the regions where they operate. Social and environmental issues that are usually ignored in such projects are increasingly affecting the financial future of multinational corporations in negative ways. In this article, we advance the argument that corporations can successfully manage these issues and that if they choose to view these management efforts as an investment rather than an expense, they may well acquire a competitive advantage over companies that do not. We describe as a case study the Camisea natural gas and condensates development project in Peru, operated by Shell Prospecting and Development Peru (SPDP). Camisea is one of the first projects anywhere in the world to conduct a detailed analysis of key industry-related social issues and the processes, required investment and financial impact of managing them. The Camisea example supports the argument that addressing social and environmental concerns makes financial sense. In present value terms, the benefit of managing these concerns was expected to surpass the cost investment by approximately US$50 million.

  7. Addressing earthquake strong ground motion issues at the Idaho National Engineering Laboratory

    SciTech Connect

    Wong, I.G. ); Silva, W.J.; Stark, C.L. ); Jackson, S.; Smith, R.P. )

    1991-01-01

    In the course of reassessing seismic hazards at the Idaho National Engineering Laboratory (INEL), several key issues have been raised concerning the effects of the earthquake source and site geology on potential strong ground motions that might be generated by a large earthquake. The design earthquake for the INEL is an approximate moment magnitude (M{sub w}) 7 event that may occur on the southern portion of the Lemhi fault, a Basin and Range normal fault that is located on the northwestern boundary of the eastern Snake River Plain and the INEL, within 10 to 27km of several major facilities. Because the locations of these facilities place them at close distances to a large earthquake and generally along strike of the causative fault, the effects of source rupture dynamics (e.g., directivity) could be critical in enhancing potential ground shaking at the INEL. An additional source issue that has been addressed is the value of stress drop to use in ground motions predictions. In terms of site geology, it has been questioned whether the interbedded volcanic stratigraphy beneath the ESRP and the INEL attenuates ground motions to a greater degree than a typical rock site in the western US. These three issues have been investigated employing a stochastic ground motion methodology which incorporates the Band-Limited-White-Noise source model for both a point source and finite fault, random vibration theory and an equivalent linear approach to model soil response.

  8. Addressing earthquake strong ground motion issues at the Idaho National Engineering Laboratory

    SciTech Connect

    Wong, I.G.; Silva, W.J.; Stark, C.L.; Jackson, S.; Smith, R.P.

    1991-12-31

    In the course of reassessing seismic hazards at the Idaho National Engineering Laboratory (INEL), several key issues have been raised concerning the effects of the earthquake source and site geology on potential strong ground motions that might be generated by a large earthquake. The design earthquake for the INEL is an approximate moment magnitude (M{sub w}) 7 event that may occur on the southern portion of the Lemhi fault, a Basin and Range normal fault that is located on the northwestern boundary of the eastern Snake River Plain and the INEL, within 10 to 27km of several major facilities. Because the locations of these facilities place them at close distances to a large earthquake and generally along strike of the causative fault, the effects of source rupture dynamics (e.g., directivity) could be critical in enhancing potential ground shaking at the INEL. An additional source issue that has been addressed is the value of stress drop to use in ground motions predictions. In terms of site geology, it has been questioned whether the interbedded volcanic stratigraphy beneath the ESRP and the INEL attenuates ground motions to a greater degree than a typical rock site in the western US. These three issues have been investigated employing a stochastic ground motion methodology which incorporates the Band-Limited-White-Noise source model for both a point source and finite fault, random vibration theory and an equivalent linear approach to model soil response.

  9. Which issues concerning multiple pregnancies should be addressed during psychosocial counselling?

    PubMed

    Emery, Marysa

    2007-01-01

    The global rise in multiple pregnancy rates due to assisted reproductive technology has led to the development of various strategies to diminish these rates without jeopardising pregnancy. Policies at treatment centres may include the option of fetal reduction, although each centre is subject to national laws and its own guidelines. However, personal opinions and goals may also influence practice. The development of clinical decisions, therefore, is complex and subject to change. Primary prevention is the best way to reduce multiple births. For preventative psychosocial counselling, some centres employ counsellors, but if not, this becomes the physician's task. An in-depth assessment is required to define how many embryos to transfer and what risk of multiple birth is acceptable to patients. Counselling should address the following: the relationship between pregnancy rate, multiple pregnancy rate and the number of embryos transferred; benefits and risks of multiple pregnancy; and possibilities for primary and secondary prevention. Patients should voice how they feel facing these issues; which issues are worrisome; how they anticipate these possibilities; and what psychosocial support exists that could be mobilized. In summary, psychosocial counselling reinforces the partnership between couples and the assisted reproductive technology team, allowing for primary prevention and informed consent on multiple pregnancy issues.

  10. Afterschool: A Strategy for Addressing and Preventing Middle School Bullying. MetLife Foundation Afterschool Alert. Issue Brief No. 51

    ERIC Educational Resources Information Center

    Afterschool Alliance, 2011

    2011-01-01

    The Afterschool Alliance, in partnership with MetLife Foundation, is proud to present the second in a series of four issue briefs examining critical issues facing middle school youth and the vital role afterschool programs play in addressing these issues. This brief focuses on bullying awareness and prevention. Bullying is a dangerous behavior…

  11. Training for lifting; an unresolved ergonomic issue?

    PubMed

    Sedgwick, A W; Gormley, J T

    1998-10-01

    The paper describes a nine year project on lifting training which included nine trans-Australia consensus conferences attended by more than 900 health professionals. Major outcomes were: (1) The essence of lifting work is the need for the performer to cope with variability in task, environment, and self, and the essence of lifting skill is therefore adaptability; (2) the semi-squat approach provides the safest and most effective basis for lifting training; (3) for lifting training to be effective, the basic principles of skill learning must be systematically applied, with adaptability as a specific goal; (4) physical work capacity (aerobic power, strength, endurance, joint mobility) is a decisive ingredient of safe and effective lifting and, in addition to skill learning, should be incorporated in the training of people engaging regularly in heavy manual work; (5) if effective compliance with recommended skilled behaviour is to be achieved, then training must apply the principles and methods appropriate to adult learning and behaviour modification.

  12. Unresolved issues in wind shear encounters

    NASA Technical Reports Server (NTRS)

    Stengel, Robert F.

    1987-01-01

    Much remains to be learned about the hazards of low altitude wind shear to aviation. New research should be conducted on the nature of the atmospheric environment, on aircraft performance, and on guidance and control aids. In conducting this research, it is important to distinguish between near-term and far-term objectives, between basic and applied research, and between uses of results for aircraft design or for real-time implementation. Advances in on-board electronics can be applied to assuring that aircraft of all classes have near optimal protection against wind shear hazards.

  13. [Unresolved issues in the DSM-5].

    PubMed

    Artigas-Pallarés, Josep; Paula-Pérez, Isabel

    2015-02-25

    This paper analyses the criticism prompted by the publication of the Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5), which was already foreseen to a certain extent during the final stages of its drafting. Part of the criticism has focused on the changes in the diagnostic criteria for certain disorders and the incorporation of new entities into the DSM. Another line of criticism, however, is aimed at the lack of diagnostic validity of the DSM, which has led to its efficiency in the research field being questioned. The basic underlying flaw in the DSM is the incoherence of a model based on a wide range of definitions of categorical entities, all of which have a high element of comorbidity. As a proposal to overcome the blockage generated in research and the scarcity of therapeutic advances, the US National Institute of Mental Health has put forward a research strategy based on identifying and studying the fundamental dimensions of the dysfunctions that present transversally in mental disorders.

  14. Management of recurrent vulvovaginal candidiasis: unresolved issues.

    PubMed

    Sobel, Jack D

    2006-11-01

    The introduction and widespread use of long-term maintenance suppressive fluconazole prophylaxis for recurrent vulvovaginal candidiasis (RVVC) has improved the quality of life for thousands of women worldwide. Moreover, the regimen is no longer expensive, and it is safe and well tolerated. However, the regimen frequently fails to cure the condition and serves only as an effective control measure in many cases. Moreover, some women are unable to tolerate the regimen, and new curative approaches are needed. This review presents the limitations of this suppressive regimen and a discussion of the possible reasons for these limitations and failure to cure. Also, the rationale for new drug development is reviewed here.

  15. Teaching undergraduate nursing students about environmental health: addressing public health issues through simulation.

    PubMed

    Stanley, Mary Jo; Rojas, Deb

    2014-01-01

    Schools of nursing are challenged to find clinical placements in public health settings. Use of simulation can address situations unique to public health, with attention to specific concerns, such as environmental health. Environmental health is an integral part of public health nursing and is a standard of professional practice. Current simulations focus on acute care situations, offering limited scenarios with a public health perspective and excluding environmental health. This study's simulation scenario was created to enhance nursing students' understanding of public health concepts within an environmental health context. Outcomes from the simulation include the need for integration of environmental issues in public health teaching. Students stated that this scenario provided a broader understanding of the environmental influences that can affect the client's and family's health. This scenario fills a void in simulation content, while providing an interactive teaching and learning strategy to help students to apply knowledge to practice.

  16. From Education to Practice: Addressing Opioid Misuse through Healthcare Provider Training: A Special Issue of SAj.

    PubMed

    Gordon, Adam J; Harding, John Daniel

    2017-03-22

    Opioid misuse may be ignored by providers who are unwilling or not confident in engaging the complex nature of substance use disorders among their patient populations. Addiction is a complex disease and although providers often are comfortable in identifying, assessing, and treating the complex diseases of their patients, basic knowledge and skills of identification, assessment, and treatment expertise involving opioids for pain, addressing opioid misuse, and treatment of opioid use disorder are lacking. Initiatives to improve knowledge of opioid use, misuse, and opioid use disorder among health care providers are emerging. In this issue of the Substance Abuse journal, we examine the science and evidence base of educational interventions and public initiatives addressing opioid use and addiction. These initiatives include naloxone rescue awareness and programs, community-based training initiatives, and system or public health approaches to improve student, trainee, and clinician education/training revolving around opioid misuse and opioid use disorder. We call on stakeholders to fund more research to investigate and implement the proven means to educate undergraduate students, graduate trainees, and clinicians regarding pain and addiction. We also recognize the 2016 peer reviewers of our journal who have performed meritorious, volunteer service to advance the science of addiction.

  17. Can Go address the multicore issues of today and the manycore problems of tomorrow?

    NASA Astrophysics Data System (ADS)

    Binet, Sébastien

    2012-06-01

    Current High Energy and Nuclear Physics (HENP) libraries and frameworks were written before multicore systems became widely deployed and used. From this environment, a 'single-thread' processing model naturally emerged but the implicit assumptions it encouraged are greatly impairing our abilities to scale in a multicore/manycore world. While parallel programming - still in an intensive phase of R&D despite the 30+ years of literature on the subject - is an obvious topic to consider, other issues (build scalability, code clarity, code deployment and ease of coding) are worth investigating when preparing for the manycore era. Moreover, if one wants to use another language than C++, a language better prepared and tailored for expressing concurrency, one also needs to ensure a good and easy reuse of already field-proven libraries. We present the work resulting from such investigations applied to the Go programming language. We first introduce the concurrent programming facilities Go is providing and how its module system addresses the build scalability and dependency hell issues. We then describe the process of leveraging the many (wo)man-years put into scientific Fortran/C/C++ libraries and making them available to the Go ecosystem. The ROOT data analysis framework, the C-BLAS library and the Herwig-6 MonteCarlo generator will be taken as examples. Finally, performances of the tools involved in a small analysis written in Go and using ROOT I/O library will be presented.

  18. Closing the gaps in knowledge, policy and action to address water issues in forests

    NASA Astrophysics Data System (ADS)

    Adams, Paul W.

    1993-10-01

    Water issues on forest lands involve many human elements and needs that are not addressed by advanced physical and biological research and technology. Major gaps in our knowledge of important patterns of climate, soils, and terrain can be filled by relatively basic data collection and monitoring programs. Careful analysis of existing data and field experience also can reveal appropriate directions for management. A focus on problem-solving can direct research more effectively towards the resolution of key issues. Despite their impact, resource policies have widely varying scientific foundations. Policy-makers need sound processes for policy development, including timely technical input that is clear, objective, and related to socio-economic considerations. Resource polices should be consistent and include not only regulation, but also research, education, assistance, and incentives. Knowledge and sound policies still may not produce the desired on-the-ground actions, however, because of variable awareness, understanding, skill, or supervision in the field. Education and training programs are important not only for resource technicians, but also for contractors, operators, and other forest workers. Good planning, communication, and field coordination further insure that problems are avoided and new opportunities for effective actions are identified.

  19. Progress in Addressing DNFSB Recommendation 2002-1 Issues: Improving Accident Analysis Software Applications

    SciTech Connect

    VINCENT, ANDREW

    2005-04-25

    Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2002-1 (''Quality Assurance for Safety-Related Software'') identified a number of quality assurance issues on the use of software in Department of Energy (DOE) facilities for analyzing hazards, and designing and operating controls to prevent or mitigate potential accidents. Over the last year, DOE has begun several processes and programs as part of the Implementation Plan commitments, and in particular, has made significant progress in addressing several sets of issues particularly important in the application of software for performing hazard and accident analysis. The work discussed here demonstrates that through these actions, Software Quality Assurance (SQA) guidance and software tools are available that can be used to improve resulting safety analysis. Specifically, five of the primary actions corresponding to the commitments made in the Implementation Plan to Recommendation 2002-1 are identified and discussed in this paper. Included are the web-based DOE SQA Knowledge Portal and the Central Registry, guidance and gap analysis reports, electronic bulletin board and discussion forum, and a DOE safety software guide. These SQA products can benefit DOE safety contractors in the development of hazard and accident analysis by precluding inappropriate software applications and utilizing best practices when incorporating software results to safety basis documentation. The improvement actions discussed here mark a beginning to establishing stronger, standard-compliant programs, practices, and processes in SQA among safety software users, managers, and reviewers throughout the DOE Complex. Additional effort is needed, however, particularly in: (1) processes to add new software applications to the DOE Safety Software Toolbox; (2) improving the effectiveness of software issue communication; and (3) promoting a safety software quality assurance culture.

  20. Ballistic Missile Defense: Actions Needed to Address Implementation Issues and Estimate Long-Term Costs for European Capabilities

    DTIC Science & Technology

    2014-04-01

    BALLISTIC MISSILE DEFENSE Actions Needed to Address Implementation Issues and Estimate Long-Term Costs for...and Estimate Long-Term Costs for European Capabilities 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...requesters April 2014 BALLISTIC MISSILE DEFENSE Actions Needed to Address Implementation Issues and Estimate Long-Term Costs for European Capabilities

  1. Addressing Issues of Broadening Participation Highlighted in the Report on the Future of Undergraduate Geoscience Education

    NASA Astrophysics Data System (ADS)

    McDaris, J. R.; Manduca, C. A.; Macdonald, H.; Iverson, E. A. R.

    2015-12-01

    The final report for the Summit on the Future of Geoscience Education lays out a consensus on issues that must be tackled by the geoscience community collectively if there are to be enough qualified people to fill the large number of expected geoscience job vacancies over the coming decade. Focus areas cited in the report include: Strengthening the connections between two-year colleges and four-year institutions Sharing and making use of successful recruitment and retention practices for students from underrepresented groups Making students aware of high-quality job prospects in the geosciences as well as its societal relevance The InTeGrate STEP Center for the Geosciences, the Supporting and Advancing Geoscience Education at Two-Year Colleges (SAGE 2YC) program, and the Building Strong Geoscience Departments (BSGD) project together have developed a suite of web resources to help faculty and program leaders begin to address these and other issues. These resources address practices that support the whole student, both in the classroom and as a part of the co-curriculum as well as information on geoscience careers, guidance for developing coherent degree programs, practical advice for mentoring and advising, and many others. In addition to developing web resources, InTeGrate has also undertaken an effort to profile successful program practices at a variety of institutions. An analysis of these data shows several common themes (e.g. proactive marketing, community building, research experiences) that align well with the existing literature on what works to support student success. But there are also indications of different approaches and emphases between Minority Serving Institutions (MSIs) and Primarily White Institutions (PWIs) as well as between different kinds of MSIs. Highlighting the different strategies in use can point both MSIs and PWIs to possible alternate solutions to the challenges their students face. InTeGrate - http

  2. 25 CFR 1000.176 - What issues must the bureau and the Tribe/Consortium address at negotiation meetings?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What issues must the bureau and the Tribe/Consortium... Tribe/Consortium address at negotiation meetings? The negotiation meetings referred to in § 1000.175 must address at a minimum the following: (a) The specific Tribe/Consortium proposal(s) and...

  3. 25 CFR 1000.176 - What issues must the bureau and the Tribe/Consortium address at negotiation meetings?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What issues must the bureau and the Tribe/Consortium... Tribe/Consortium address at negotiation meetings? The negotiation meetings referred to in § 1000.175 must address at a minimum the following: (a) The specific Tribe/Consortium proposal(s) and...

  4. 25 CFR 1000.176 - What issues must the bureau and the Tribe/Consortium address at negotiation meetings?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What issues must the bureau and the Tribe/Consortium... Tribe/Consortium address at negotiation meetings? The negotiation meetings referred to in § 1000.175 must address at a minimum the following: (a) The specific Tribe/Consortium proposal(s) and...

  5. 25 CFR 1000.176 - What issues must the bureau and the Tribe/Consortium address at negotiation meetings?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What issues must the bureau and the Tribe/Consortium... Tribe/Consortium address at negotiation meetings? The negotiation meetings referred to in § 1000.175 must address at a minimum the following: (a) The specific Tribe/Consortium proposal(s) and...

  6. 25 CFR 1000.176 - What issues must the bureau and the Tribe/Consortium address at negotiation meetings?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What issues must the bureau and the Tribe/Consortium... Tribe/Consortium address at negotiation meetings? The negotiation meetings referred to in § 1000.175 must address at a minimum the following: (a) The specific Tribe/Consortium proposal(s) and...

  7. 32 CFR Appendix C to Part 22 - Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions C Appendix C to Part 22 National Defense Department of Defense... AND ADMINISTRATION Pt. 22, App. C Appendix C to Part 22—Administrative Requirements and Issues To...

  8. 32 CFR Appendix C to Part 22 - Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions C Appendix C to Part 22 National Defense Department of Defense... AND ADMINISTRATION Pt. 22, App. C Appendix C to Part 22—Administrative Requirements and Issues To...

  9. 32 CFR Appendix C to Part 22 - Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Administrative Requirements and Issues To Be Addressed in Award Terms and Conditions C Appendix C to Part 22 National Defense Department of Defense... AND ADMINISTRATION Pt. 22, App. C Appendix C to Part 22—Administrative Requirements and Issues To...

  10. A modular approach to addressing model design, scale, and parameter estimation issues in distributed hydrological modelling

    USGS Publications Warehouse

    Leavesley, G.H.; Markstrom, S.L.; Restrepo, P.J.; Viger, R.J.

    2002-01-01

    A modular approach to model design and construction provides a flexible framework in which to focus the multidisciplinary research and operational efforts needed to facilitate the development, selection, and application of the most robust distributed modelling methods. A variety of modular approaches have been developed, but with little consideration for compatibility among systems and concepts. Several systems are proprietary, limiting any user interaction. The US Geological Survey modular modelling system (MMS) is a modular modelling framework that uses an open source software approach to enable all members of the scientific community to address collaboratively the many complex issues associated with the design, development, and application of distributed hydrological and environmental models. Implementation of a common modular concept is not a trivial task. However, it brings the resources of a larger community to bear on the problems of distributed modelling, provides a framework in which to compare alternative modelling approaches objectively, and provides a means of sharing the latest modelling advances. The concepts and components of the MMS are described and an example application of the MMS, in a decision-support system context, is presented to demonstrate current system capabilities. Copyright ?? 2002 John Wiley and Sons, Ltd.

  11. Addressing issues associated with evaluating prediction models for survival endpoints based on the concordance statistic.

    PubMed

    Wang, Ming; Long, Qi

    2016-09-01

    Prediction models for disease risk and prognosis play an important role in biomedical research, and evaluating their predictive accuracy in the presence of censored data is of substantial interest. The standard concordance (c) statistic has been extended to provide a summary measure of predictive accuracy for survival models. Motivated by a prostate cancer study, we address several issues associated with evaluating survival prediction models based on c-statistic with a focus on estimators using the technique of inverse probability of censoring weighting (IPCW). Compared to the existing work, we provide complete results on the asymptotic properties of the IPCW estimators under the assumption of coarsening at random (CAR), and propose a sensitivity analysis under the mechanism of noncoarsening at random (NCAR). In addition, we extend the IPCW approach as well as the sensitivity analysis to high-dimensional settings. The predictive accuracy of prediction models for cancer recurrence after prostatectomy is assessed by applying the proposed approaches. We find that the estimated predictive accuracy for the models in consideration is sensitive to NCAR assumption, and thus identify the best predictive model. Finally, we further evaluate the performance of the proposed methods in both settings of low-dimensional and high-dimensional data under CAR and NCAR through simulations.

  12. Main issues addressed in the 2014-2015 revisions to the OECD Genetic Toxicology Test Guidelines.

    PubMed

    Thybaud, Veronique; Lorge, Elisabeth; Levy, Dan D; van Benthem, Jan; Douglas, George R; Marchetti, Francesco; Moore, Martha M; Schoeny, Rita

    2017-03-07

    The Organization for Economic Cooperation and Development (OECD) recently revised the test guidelines (TGs) for genetic toxicology. This article describes the main issues addressed during the revision process, and the new and consistent recommendations made in the revised TGs for: (1) demonstration of laboratory proficiency; (2) generation and use of robust historical control data; (3) improvement of the statistical power of the tests; (4) selection of top concentration for in vitro assays; (5) consistent data interpretation and determination of whether the result is clearly positive, clearly negative or needs closer consideration; and, (6) consideration of 3R's for in vivo assay design. The revision process resulted in improved consistency among OECD TGs (including the newly developed ones) and more comprehensive recommendations for the conduct and the interpretation of the assays. Altogether, the recommendations made during the revision process should improve the efficiency, by which the data are generated, and the quality and reliability of test results. Environ. Mol. Mutagen., 2017. © 2017 Wiley Periodicals, Inc.

  13. Addressing issues associated with evaluating prediction models for survival endpoints based on the concordance statistic

    PubMed Central

    Wang, Ming; Long, Qi

    2016-01-01

    Summary Prediction models for disease risk and prognosis play an important role in biomedical research, and evaluating their predictive accuracy in the presence of censored data is of substantial interest. The standard concordance (c) statistic has been extended to provide a summary measure of predictive accuracy for survival models. Motivated by a prostate cancer study, we address several issues associated with evaluating survival prediction models based on c–statistic with a focus on estimators using the technique of inverse probability of censoring weighting (IPCW). Compared to the existing work, we provide complete results on the asymptotic properties of the IPCW estimators under the assumption of coarsening at random (CAR), and propose a sensitivity analysis under the mechanism of noncoarsening at random (NCAR). In addition, we extend the IPCW approach as well as the sensitivity analysis to high-dimensional settings. The predictive accuracy of prediction models for cancer recurrence after prostatectomy are assessed by applying the proposed approaches. We find that the estimated predictive accuracy for the models in consideration is sensitive to NCAR assumption, and thus identify the best predictive model. Finally, we further evaluate the performance of the proposed methods in both settings of low-dimensional and high-dimensional data under CAR and NCAR through simulations. PMID:26756274

  14. Classification of spatially unresolved objects

    NASA Technical Reports Server (NTRS)

    Nalepka, R. F.; Horwitz, H. M.; Hyde, P. D.; Morgenstern, J. P.

    1972-01-01

    A proportion estimation technique for classification of multispectral scanner images is reported that uses data point averaging to extract and compute estimated proportions for a single average data point to classify spatial unresolved areas. Example extraction calculations of spectral signatures for bare soil, weeds, alfalfa, and barley prove quite accurate.

  15. Unresolved crisis in medical education.

    PubMed

    Monif, G R; Severin, M J

    1994-01-01

    A crisis exists in medical education. Changes in methodology have diverted attention from synthesis to mass accumulation of factual data. The response to this crisis has been largely focused on a shell game involving new pathways and curriculum changes without addressing the critical issue of what constitutes education. The ultimate problem in medical education is a crisis of leadership. Until education is given a priority status and the obligations to teach on the part of medical educators and to learn on the part of students are translated into a creative policy by those who can lead, the wheels of learning will continue to spin without significant progress.

  16. Pursuing Justice for Refugee Students: Addressing Issues of Cultural (Mis)Recognition

    ERIC Educational Resources Information Center

    Keddie, Amanda

    2012-01-01

    In this paper Nancy Fraser's conceptual tools are drawn on to theorise issues of justice in a culturally diverse primary school in Australia where approximately 30% of the student population are immigrant/refugees. The paper examines justice issues of cultural recognition in relation to refugee student identity, behaviour and assessment. Drawing…

  17. A Consideration to Two Main Ethical Issues in Educational Research, and How May These Be Addressed

    ERIC Educational Resources Information Center

    Abed, Mohaned Ghazi

    2015-01-01

    This paper has firstly discussed the topic of Ethical Issues in Education, and has accordingly highlighted the fact that ethics are not something to deem at the commencement of a research project or fieldwork, but rather throughout the entire research process. Furthermore, two of the most important ethical issues have been given…

  18. ISSUES THAT MUST BE ADDRESSED FOR RISK ASSESSMENT OF MIXED EXPOSURES: THE EPA EXPERIENCE WITH AIR QUALITY

    EPA Science Inventory

    Issues that Must be Addressed for Risk Assessment of Mixed Exposures: The EPA Experience with Air Quality

    Daniel L. Costa, Sc.D.

    Abstract
    Humans are routinely exposed to a complex mixture of air pollutants in both their outdoor and indoor environments. The wide...

  19. Dilemmas with Dilemmas...Exploring the Suitability of Dilemma Stories as a Way of Addressing Ethical Issues in Science Education.

    ERIC Educational Resources Information Center

    Settelmaier, Elisabeth

    Traditionally, many science educators have taught science without addressing ethical questions. However, the inclusion of moral discourse in science teaching may help educators to bring to the fore problematic issues in relation to science, and it may offer an opportunity for students to practice their future engagement in the public discourse…

  20. Teaching for Change: Addressing Issues of Difference in the College Classroom. Reprint Series No. 25. Harvard Educational Review.

    ERIC Educational Resources Information Center

    Geismar, Kathryn, Ed.; Nicoleau, Guitele, Ed.

    Contributors to this collection of essays describe how they address issues of race, gender, and class in their college courses as they attempt to ensure that their curricula and class discussions represent the perspectives of all students. Essays include: (1) "Introduction" (Kathryn Giesmar and Guitele Nicoleau); (2) "Dialogue…

  1. Core Issues that Must be Addressed in Order to Improve Vocational Education and Training in Indonesia. An Institutional Analysis

    ERIC Educational Resources Information Center

    Cully, John H.

    2007-01-01

    Indonesia, like many other countries has to come to terms with the challenges of a rapidly advancing economic globalization. In order to address the major issues involved the government must take some very essential steps that are practical, attainable and sustainable. With global economies evolving from a traditional resource structure to that of…

  2. Encouraging Pre-Service Teachers to Address Issues of Sexual Orientation in Their Classrooms: Walking the Walk & Talking the Talk

    ERIC Educational Resources Information Center

    Hansen, Laurie E.

    2015-01-01

    The purpose of this article is to describe ways that teacher educators can encourage future teachers to address lesbian, gay, bisexual, or transgender (LGBT) issues in their own classrooms. The Gay, Lesbian, Straight Education Network's ThinkB4YouSpeak Educator's Guide served as the framework for the activities that the author has implemented in…

  3. Bridging the Gap: Essential Issues to Address in Recurring Writing Center Appointments with Chinese ELL Students

    ERIC Educational Resources Information Center

    Nan, Frances

    2012-01-01

    As the population of international--and particularly Chinese--students grows in US academic institutions, it is critical that writing center tutors be able to address these students' needs. However, whereas writing tutors at the author's institution are often taught to be indirect and focus on higher order concerns, such strategies are not always…

  4. Open Lives, Safe Schools: Addressing Gay and Lesbian Issues in Education.

    ERIC Educational Resources Information Center

    Walling, Donovan R., Ed.

    In all but a handful of states, it is legal to discriminate against individuals on the basis of sexual orientation. Ways in which homophobia and anti-gay sentiments affect education in the United States are addressed in this collection of essays. They are written for educators and others concerned about schooling, from kindergarten through…

  5. Governors' Top Education Issues: 2015 State of the State Addresses. ECS Education Trends

    ERIC Educational Resources Information Center

    Aragon, Stephanie; Rowland, Julie

    2015-01-01

    Education Commission of the States (ECS) strives to keep its constituency apprised of education policy trends across the states. To provide a comprehensive overview of educational priorities outlined by governors, ECS summarized the education proposals and accomplishments detailed in every 2015 State of the State address delivered to date. Each…

  6. Addressing Agricultural Issues in Health Care Education: An Occupational Therapy Curriculum Program Description

    ERIC Educational Resources Information Center

    Smallfield, Stacy; Anderson, Angela J.

    2008-01-01

    Context: Medical and allied health professionals who work in agricultural states frequently address the needs of clients who live and work in rural and frontier environments. The primary occupations of those living in rural areas include farming, ranching, or other agriculture-related work. Farming is consistently ranked as one of the most…

  7. Teaching Water: Connecting across Disciplines and into Daily Life to Address Complex Societal Issues

    ERIC Educational Resources Information Center

    Eisen, Arri; Hall, Anne; Lee, Tong Soon; Zupko, Jack

    2009-01-01

    A central problem in higher education is how to best develop in students interdisciplinary thinking and application skills necessary to work and engage effectively in the twenty-first century. Traditional university structures make addressing this problem especially challenging. Using as a model courses with diverse perspectives on water taught by…

  8. Afterschool in Action: How Innovative Afterschool Programs Address Critical Issues Facing Middle School Youth

    ERIC Educational Resources Information Center

    Afterschool Alliance, 2012

    2012-01-01

    Over the last four years, the Afterschool Alliance and MetLife Foundation have worked together to identify exemplary, and often lesser-known afterschool programs across the nation. For the past two years, efforts have focused on finding innovative afterschool programs serving middle school students. This focus was developed to address the need for…

  9. Standards, Assessment, and Readiness: Addressing Postsecondary Transition Issues across State Lines

    ERIC Educational Resources Information Center

    Michelau, Demarée K.

    2015-01-01

    This brief describes major challenges ahead for states, institutions, and most importantly, students as the standards and assessments from the Common Core Standards (CCSS) are implemented. It also offers recommendations to create a network structure that would assist K-12 and higher education leaders in addressing those challenges. To begin the…

  10. Addressing Air, Land & Water Nitrogen Issues under Changing Climate Trends & Variability

    EPA Science Inventory

    The climate of western U.S. dairy producing states is anticipated to change significantly over the next 50 to 75 years. A multimedia modeling system based upon the “nitrogen cascade” concept has been configured to address three aspects of sustainability (environmenta...

  11. 2016 State of the State Addresses: Governors' Top Education Issues. Education Trends

    ERIC Educational Resources Information Center

    Auck, Alyssa; Railey, Hunter

    2016-01-01

    Each year, governors take the stage to highlight accomplishments and outline policy priorities for their states. In an effort to provide up-to-date information on education policy trends, Education Commission of the States tracks all education policy proposals and accomplishments featured by governors in these State of the State addresses. At the…

  12. Extending Transition to Address Guardianship Alternatives: An Issue Concerning Students Who Have Intellectual Disability

    ERIC Educational Resources Information Center

    Millar, Dorothy Squatrito

    2014-01-01

    As students who have intellectual disability reach or have reached the age of majority, concerns regarding their competence to make informed decisions are often raised, as is the issue of adult guardianship. Guardianship refers to when a judge appoints an adult to be the guardian of another adult (ward) who has been determined to be unable to care…

  13. Rural Special Education Curriculum Issues: Competency-Based Curriculum Addressing Graduation and Grading Alternatives.

    ERIC Educational Resources Information Center

    McKay, Norlis

    The paper introduces issues regarding graduation of handicapped students. Modifications to graduation requirements include course substitutions; curricular, method, evaluation or materials modification; and additional time allotted for completion of the degree requirements. Requirements for graduation from Show Low High School are listed under the…

  14. Contemporary Issues on Campuses: Today's Activities Professionals Must Address Everything from AIDS Education to Crime Prevention.

    ERIC Educational Resources Information Center

    Scopes, Jack

    1990-01-01

    Some approaches to dealing with contemporary issues on campus include Acquired Immune Deficiency Syndrome awareness--safe sex parties; crime prevention--students helping students, legislation, workshops and conferences; alcohol awareness--designated driver program and starting a nonalcoholic bar; cults on campus; sexual assault--"Hours Til…

  15. Skirting the Issue: Teachers' Experiences "Addressing Sexuality in Middle School Language Arts"

    ERIC Educational Resources Information Center

    Puchner, Laurel; Klein, Nicole Aydt

    2012-01-01

    The goal of this study was to examine perceptions, attitudes, and reported practices of a group of middle level Language Arts teachers concerning sexuality-related issues. Through interviews with 15 teachers, the study found that sexuality was in one sense pervasive, as it came up frequently in the teachers' practice. Yet at the same time the…

  16. School-Based Programs Addressing Gay/Lesbian/Bisexual Youth Issues.

    ERIC Educational Resources Information Center

    Rienzo, Barbara A.; And Others

    1997-01-01

    Homosexual adolescents are at risk within schools for many health problems. Hostile school environments can often exacerbate their problems. This article summarizes research on issues related to youth sexual orientation, noting controversies surrounding school involvement in the United States and describing programs instituted by school…

  17. The Spiritual Dimension of Education--Addressing Issues of Identity and Belonging

    ERIC Educational Resources Information Center

    de Souza, Marian

    2016-01-01

    In a shrinking world where events across the globe become relevant for the lives of masses of people regardless of the distances that divide them, some serious issues have arisen which have particular significance for education policies and practice. Too many children are growing up against a backdrop of polarised views and attitudes which is a…

  18. Science Teachers' Use of Mass Media to Address Socio-Scientific and Sustainability Issues

    ERIC Educational Resources Information Center

    Klosterman, Michelle L.; Sadler, Troy D.; Brown, Julie

    2012-01-01

    The currency, relevancy and changing nature of science makes it a natural topic of focus for mass media outlets. Science teachers and students can capitalize on this wealth of scientific information to explore socio-scientific and sustainability issues; however, without a lens on how those media are created and how representations of science are…

  19. Where We Live: A Curriculum Guide. ABE Materials that Address Housing Issues.

    ERIC Educational Resources Information Center

    Ellowitch, Azi

    This curriculum was developed to give adult basic education (ABE) teachers starting points for developing their own units around housing-related issues. The texts have been chosen thematically, rather than by skill level. The materials are designed for group work--oral reading and discussion. Readings focus on housing repairs, court procedures,…

  20. History Museums and Social Cohesion: Building Identity, Bridging Communities, and Addressing Difficult Issues

    ERIC Educational Resources Information Center

    Rosenberg, Tracy Jean

    2011-01-01

    Museums have the capacity to enhance social cohesion, which is the product of a trusting, connected community. History museums and historic sites, in particular, can serve communities by stimulating dialogue on difficult issues, accurately representing all the people of a nation, and creating forums for discussion among groups with disparate…

  1. A Critical Look at Physical Education and What Must Be Done to Address Obesity Issues

    ERIC Educational Resources Information Center

    Prusak, Keven; Graser, Susan Vincent; Pennington, Todd; Zanandrea, Maria; Wilkinson, Carol; Hager, Ron

    2011-01-01

    Historically, physical education (PE) has been designed to do one thing--teach sport skills. However, it is now being asked to deal with lifestyle issues such as obesity and inactivity. Since the target and purposes of PE have changed, a fundamental shift in the way it is delivered is essential to its survival. This article highlights some…

  2. Policing Matters: Addressing the Controversial Issue of Policing through Education for Reconciliation

    ERIC Educational Resources Information Center

    Cusack, Mella

    2009-01-01

    Policing is widely held to constitute a contentious issue in classrooms on both sides of the border on the island of Ireland, despite the fact that the ongoing peace process has led to a normalising of cross-border policing relationships. The Education for Reconciliation Project works with teachers and members of the two police services to produce…

  3. Progression in Ethical Reasoning When Addressing Socio-Scientific Issues in Biotechnology

    ERIC Educational Resources Information Center

    Berne, Birgitta

    2014-01-01

    This article reports on the outcomes of an intervention in a Swedish school in which the author, a teacher-researcher, sought to develop students' (14-15 years old) ethical reasoning in science through the use of peer discussions about socio-scientific issues. Prior to the student discussions various prompts were used to highlight different…

  4. Addressing lesbian, gay, bisexual, and transgender issues from the inside: one federal agency's approach.

    PubMed

    Craft, E M; Mulvey, K P

    2001-06-01

    The mission of the Substance Abuse and Mental Health Services Administration (SAMHSA) is to protect and serve underserved and vulnerable populations. Congress established SAMHSA under Public Law 102-321 on October 1, 1992, to strengthen the nation's health care capacity to provide prevention, diagnosis, and treatment services for substance abuse and mental illnesses. SAMHSA works in partnership with states, communities, and private organizations to address the needs of people with substance abuse and mental illnesses as well as the community risk factors that contribute to these illnesses. As part of its efforts to address the unique needs of special populations, SAMHSA has reached out to the lesbian, gay, bisexual, and transgender (LGBT) community. SAMHSA and its centers (Center for Substance Abuse Treatment, Center for Substance Abuse Prevention, and Center for Mental Health Services) have made a concerted effort, through both policy and programs, to develop services responsive to this community.

  5. Evaluating programs that address ideological issues: ethical and practical considerations for practitioners and evaluators.

    PubMed

    Lieberman, Lisa D; Fagen, Michael C; Neiger, Brad L

    2014-03-01

    There are important practical and ethical considerations for organizations in conducting their own, or commissioning external, evaluations and for both practitioners and evaluators, when assessing programs built on strongly held ideological or philosophical approaches. Assessing whether programs "work" has strong political, financial, and/or moral implications, particularly when expending public dollars, and may challenge objectivity about a particular program or approach. Using a case study of the evaluation of a school-based abstinence-until-marriage program, this article discusses the challenges, lessons learned, and ethical responsibilities regarding decisions about evaluation, specifically associated with ideologically driven programs. Organizations should consider various stakeholders and views associated with their program to help identify potential pitfalls in evaluation. Once identified, the program or agency needs to carefully consider its answers to two key questions: Do they want the answer and are they willing to modify the program? Having decided to evaluate, the choice of evaluator is critical to assuring that ethical principles are maintained and potential skepticism or criticism of findings can be addressed appropriately. The relationship between program and evaluator, including agreements about ownership and eventual publication and/or promotion of data, should be addressed at the outset. Programs and organizations should consider, at the outset, their ethical responsibility when findings are not expected or desired. Ultimately, agencies, organizations, and programs have an ethical responsibility to use their data to provide health promotion programs, whether ideologically founded or not, that appropriately and effectively address the problems they seek to solve.

  6. Policing Matters: Addressing the Controversial Issue of Policing Through Education for Reconciliation

    NASA Astrophysics Data System (ADS)

    Cusack, Mella

    2009-05-01

    Policing is widely held to constitute a contentious issue in classrooms on both sides of the border on the island of Ireland, despite the fact that the ongoing peace process has led to a normalising of cross-border policing relationships. The Education for Reconciliation Project works with teachers and members of the two police services to produce teaching/learning modules on law and policing for use in Citizenship Education classrooms. This paper examines the commonly-held teacher perception of policing as a controversial issue and the reasons why these perceptions exist. It takes into consideration the opinion that it is time for schools to begin work on policing, and investigates the implications for practice.

  7. Approaches of the German food industry for addressing the issue of food losses.

    PubMed

    Richter, Beate; Bokelmann, Wolfgang

    2016-02-01

    In the food industry the subject of food losses is of great importance due to economic balance and an efficient application of resources as well as the development of an efficient food chain system. This paper presents the explorative results of a quantitative survey of leading companies of the German food industry to evaluate the relevance and handling of this issue. The investigation reveals that the topic food losses have a high significance in the food industry which will probably increase in future. A sample breakdown by branches indicates that the issue has the highest relevance for companies in the confectionery industry. These companies as well as those in the meat and fish industry want to consider the subject prospectively more powerful in their companies. Across the food industry, there is no communication to consumers of the efforts concerning food losses. And companies in the confectionery industry and in the fruit and vegetable industry rather want to engage more powerful in this topic if consumers' interest increases. But in order to minimize food losses at all stages along the supply chain, communication and collaboration at all stages is essential, especially the communication to consumers. Thus, it has to be verified whether a suitable communication can lead to advantages in competition and become an important issue for companies to differentiate from competitors.

  8. Progression in Ethical Reasoning When Addressing Socio-scientific Issues in Biotechnology

    NASA Astrophysics Data System (ADS)

    Berne, Birgitta

    2014-11-01

    This article reports on the outcomes of an intervention in a Swedish school in which the author, a teacher-researcher, sought to develop students' (14-15 years old) ethical reasoning in science through the use of peer discussions about socio-scientific issues. Prior to the student discussions various prompts were used to highlight different aspects of the issues. In addition, students were given time to search for further information themselves. Analysis of students' written arguments, from the beginning of the intervention and afterwards, suggests that many students seem to be moving away from their use of everyday language towards using scientific concepts in their arguments. In addition, they moved from considering cloning and 'designer babies' solely in terms of the present to considering them in terms of the future. Furthermore, the students started to approach the issues in additional ways using not only consequentialism but also the approaches of virtue ethics, and rights and duties. Students' progression in ethical reasoning could be related to the characteristics of the interactions in peer discussions as students who critically and constructively argued with each other's ideas, and challenged each other's claims, made progress in more aspects of ethical reasoning than students merely using cumulative talk. As such, the work provides valuable indications for the importance of introducing peer discussions and debates about SSIs in connection to biotechnology into the teaching of science in schools.

  9. Religiosity/spirituality of German doctors in private practice and likelihood of addressing R/S issues with patients.

    PubMed

    Voltmer, Edgar; Bussing, Arndt; Koenig, Harold G; Al Zaben, Faten

    2014-12-01

    This study examined the self-assessed religiosity and spirituality (R/S) of a representative sample of German physicians in private practice (n = 414) and how this related to their addressing R/S issues with patients. The majority of physicians (49.3 %)reported a Protestant denomination, with the remainder indicating mainly either Catholic(12.5 %) or none (31.9 %). A significant proportion perceived themselves as either religious(42.8 %) or spiritual (29.0 %). Women were more likely to rate themselves R/S than did men. Women (compared to men) were also somewhat more likely to attend religious services (7.4 vs. 2.1 % at least once a week) and participate in private religious activities(14.9 vs. 13.7 % at least daily), although these differences were not statistically significant.The majority of physicians (67.2 %) never/seldom addressed R/S issues with a typical patient. Physicians with higher self-perceived R/S and more frequent public and private religious activity were much more likely to address R/S issues with patients. Implications for patient care and future research are discussed.

  10. Advocacy to action: addressing coordinated school health program issues with school boards.

    PubMed

    Wiley, David C; Howard-Barr, Elissa M

    2005-01-01

    As the need for Coordinated School Health Programs (CSHP) increases, so does recognition of the importance for advocating with local school boards for their support. Identifying the diversified make up of school board members and implementing effective strategies to advocate for coordinated school health can help facilitate the successful inclusion of such a program. With increasing emphasis placed on standardized testing and the "basic" curriculum, school board members need to become aware of specific benefits a CSHP can provide their district. With the relationship between health status and academic achievement confirmed in scientific research, school boards may begin paying more attention to providing high-quality health services and health instruction for students. This article presents items to consider and steps to take before, during, and after addressing a local school board for their support in implementing a CSHP.

  11. Nutritional issues for older adults: addressing degenerative ageing with long-term studies.

    PubMed

    de Groot, Lisette C P G M

    2016-05-01

    The ageing process is influenced by a variety of factors, including extrinsic, malleable lifestyle variables. The present paper deals with the epidemiological evidence for the role of dietary patterns and key nutritional concerns in relation to survival and ageing-related disorders that present themselves in later life. Healthful dietary patterns appear to be most relevant in old age. Specific nutritional concerns are related to vitamin D, vitamin B12 and protein malnutrition. An important challenge to further expand the knowledge base is currently addressed by the NuAge project, acknowledging the complexity of the ageing process and integrating different dimensions of research into human healthy ageing. In the meantime, reversing poor adherence to existing guidelines for a healthy diet remains a first challenge in public health nutritional practices.

  12. Introduction: what are the issues in addressing the allergenic potential of genetically modified foods?

    PubMed Central

    Metcalfe, Dean D

    2003-01-01

    There is growing concern among the general public and the scientific community regarding the potential toxicity of genetically modified organisms (GMOs). The use of biotechnology to enhance pest resistance or nutritional value has raised a number of fundamental questions including the consequences of insertion of reporter genes, the spread of resistance genes to surrounding plants, and the use of suicide genes to prohibit reuse of seed from engineered plants. Of particular interest is the ability of proteins from GMOs to elicit potentially harmful immunologic responses, including allergic hypersensitivity. The lack of information of the potential toxicity of these products suggests a need to identify the critical issues and research needs regarding these materials and to develop testing strategies to examine the allergenicity of these compounds. PMID:12826482

  13. Introduction: what are the issues in addressing the allergenic potential of genetically modified foods?

    PubMed

    Metcalfe, Dean D

    2003-06-01

    There is growing concern among the general public and the scientific community regarding the potential toxicity of genetically modified organisms (GMOs). The use of biotechnology to enhance pest resistance or nutritional value has raised a number of fundamental questions including the consequences of insertion of reporter genes, the spread of resistance genes to surrounding plants, and the use of suicide genes to prohibit reuse of seed from engineered plants. Of particular interest is the ability of proteins from GMOs to elicit potentially harmful immunologic responses, including allergic hypersensitivity. The lack of information of the potential toxicity of these products suggests a need to identify the critical issues and research needs regarding these materials and to develop testing strategies to examine the allergenicity of these compounds.

  14. A public-policy practicum to address current issues in human, animal, and ecosystem health.

    PubMed

    Herrmann, John A; Johnson, Yvette J; Troutt, H Fred; Prudhomme, Thomas

    2009-01-01

    There are recognized needs for cross-training health professionals in human, animal, and ecosystem health and for public health policy to be informed by experts from medical, science, and social science disciplines. Faculty members of the Community Health and Preventive Medicine Section at the University of Illinois at Urbana-Champaign, College of Veterinary Medicine, and the Institute of Government and Public Affairs, University of Illinois at Urbana-Champaign, have offered a public-policy course designed to meet those needs. The course was designed as a practicum to teach students the policy-making process through the development of policy proposals and to instruct students on how to effectively present accurate scientific, demographic, and statistical information to policy makers and to the public. All students substantially met the learning objectives of the course. This course represents another model that can be implemented to help students learn about complex, multifactorial issues that affect the health of humans, animals, and ecosystems, while promoting participation in public health policy development.

  15. Addressing the amorphous content issue in quantitative phase analysis : the certification of NIST SRM 676a.

    SciTech Connect

    Cline, J. P.; Von Dreele, R. B.; Winburn, R.; Stephens, P. W.; Filliben, J. J.

    2011-07-01

    A non-diffracting surface layer exists at any boundary of a crystal and can comprise a mass fraction of several percent in a finely divided solid. This has led to the long-standing issue of amorphous content in standards for quantitative phase analysis (QPA). NIST standard reference material (SRM) 676a is a corundum ({alpha}-Al{sub 2}O{sub 3}) powder, certified with respect to phase purity for use as an internal standard in powder diffraction QPA. The amorphous content of SRM 676a is determined by comparing diffraction data from mixtures with samples of silicon powders that were engineered to vary their specific surface area. Under the (supported) assumption that the thickness of an amorphous surface layer on Si was invariant, this provided a method to control the crystalline/amorphous ratio of the silicon components of 50/50 weight mixtures of SRM 676a with silicon. Powder diffraction experiments utilizing neutron time-of-flight and 25 keV and 67 keV X-ray energies quantified the crystalline phase fractions from a series of specimens. Results from Rietveld analyses, which included a model for extinction effects in the silicon, of these data were extrapolated to the limit of zero amorphous content of the Si powder. The certified phase purity of SRM 676a is 99.02% {+-} 1.11% (95% confidence interval). This novel certification method permits quantification of amorphous content for any sample of interest, by spiking with SRM 676a.

  16. Evaluation of Geese Theatre's Re-Connect program: addressing resettlement issues in prison.

    PubMed

    Harkins, Leigh; Pritchard, Cecilia; Haskayne, Donna; Watson, Andy; Beech, Anthony R

    2011-06-01

    This study examined the impact of Geese Theatre's Re-Connect program on a sample of offenders who attended it. This program used theatre performance, experiential exercises, skills practice role-plays, and metaphors such as the masks to invite a group of offenders to consider and explore issues connected with their release and reconnecting with a life outside prison. Pre- and postprogram psychometric tests, behavior ratings, and interviews were completed to assess the effectiveness of the program. Significant changes were observed from pre- to posttreatment in terms of self-efficacy, motivation to change, and improved confidence in skills (i.e., social and friendship, occupational, family and intimacy, dealing with authority, alternatives to aggression or offending, and self-management and self-control skills). Improved behavior and engagement within the program was observed over the 3 days of the program. Interviews also revealed the positive impact the program had on the participants. This provides evidence supporting the short-term effectiveness of the Re-Connect program.

  17. Addressing practical issues related to nursing care for international visitors to Hiroshima.

    PubMed

    Nishikawa, Mariko; Niiya, Kiyoka; Okayasu, Masako

    2014-04-01

    When nine million foreigners visited Japan in 2013, the federal government set a goal to attract an additional two and a half million visitors including medical tourists by 2020. This research investigates the attitudes and concerns of Japanese nurses when they are in a situation dealing with foreign patients. The data were collected from March through September 2010, from 114 nurses at three hospitals, in close proximity to popular tourist destinations in Hiroshima. A questionnaire was developed for this research, named Mari Meter, which included a section to write answers to an open question for the nurses to express their opinions. These responses were examined statistically and by word analysis using Text Mining Studio. Japanese nurses expressed greatest concern about payment options, foreign language skills, and issues of informed consent, when dealing with foreigners. The results confirm that, in order to provide a high quality of patient care, extra preparation and a greater knowledge of international workers and visitors are required by nursing professionals in Japan.

  18. Addressing the ethical issues raised by synthetic human entities with embryo-like features

    PubMed Central

    Aach, John; Lunshof, Jeantine; Iyer, Eswar; Church, George M

    2017-01-01

    The "14-day rule" for embryo research stipulates that experiments with intact human embryos must not allow them to develop beyond 14 days or the appearance of the primitive streak. However, recent experiments showing that suitably cultured human pluripotent stem cells can self-organize and recapitulate embryonic features have highlighted difficulties with the 14-day rule and led to calls for its reassessment. Here we argue that these and related experiments raise more foundational issues that cannot be fixed by adjusting the 14-day rule, because the framework underlying the rule cannot adequately describe the ways by which synthetic human entities with embryo-like features (SHEEFs) might develop morally concerning features through altered forms of development. We propose that limits on research with SHEEFs be based as directly as possible on the generation of such features, and recommend that the research and bioethics communities lead a wide-ranging inquiry aimed at mapping out solutions to the ethical problems raised by them. DOI: http://dx.doi.org/10.7554/eLife.20674.001

  19. Methods to address poultry robustness and welfare issues through breeding and associated ethical considerations.

    PubMed

    Muir, William M; Cheng, Heng-Wei; Croney, Candace

    2014-01-01

    As consumers and society in general become more aware of ethical and moral dilemmas associated with intensive rearing systems, pressure is put on the animal and poultry industries to adopt alternative forms of housing. This presents challenges especially regarding managing competitive social interactions between animals. However, selective breeding programs are rapidly advancing, enhanced by both genomics and new quantitative genetic theory that offer potential solutions by improving adaptation of the bird to existing and proposed production environments. The outcomes of adaptation could lead to improvement of animal welfare by increasing fitness of the animal for the given environments, which might lead to increased contentment and decreased distress of birds in those systems. Genomic selection, based on dense genetic markers, will allow for more rapid improvement of traits that are expensive or difficult to measure, or have a low heritability, such as pecking, cannibalism, robustness, mortality, leg score, bone strength, disease resistance, and thus has the potential to address many poultry welfare concerns. Recently selection programs to include social effects, known as associative or indirect genetic effects (IGEs), have received much attention. Group, kin, multi-level, and multi-trait selection including IGEs have all been shown to be highly effective in reducing mortality while increasing productivity of poultry layers and reduce or eliminate the need for beak trimming. Multi-level selection was shown to increases robustness as indicated by the greater ability of birds to cope with stressors. Kin selection has been shown to be easy to implement and improve both productivity and animal well-being. Management practices and rearing conditions employed for domestic animal production will continue to change based on ethical and scientific results. However, the animal breeding tools necessary to provide an animal that is best adapted to these changing conditions

  20. Methods to address poultry robustness and welfare issues through breeding and associated ethical considerations

    PubMed Central

    Muir, William M.; Cheng, Heng-Wei; Croney, Candace

    2014-01-01

    As consumers and society in general become more aware of ethical and moral dilemmas associated with intensive rearing systems, pressure is put on the animal and poultry industries to adopt alternative forms of housing. This presents challenges especially regarding managing competitive social interactions between animals. However, selective breeding programs are rapidly advancing, enhanced by both genomics and new quantitative genetic theory that offer potential solutions by improving adaptation of the bird to existing and proposed production environments. The outcomes of adaptation could lead to improvement of animal welfare by increasing fitness of the animal for the given environments, which might lead to increased contentment and decreased distress of birds in those systems. Genomic selection, based on dense genetic markers, will allow for more rapid improvement of traits that are expensive or difficult to measure, or have a low heritability, such as pecking, cannibalism, robustness, mortality, leg score, bone strength, disease resistance, and thus has the potential to address many poultry welfare concerns. Recently selection programs to include social effects, known as associative or indirect genetic effects (IGEs), have received much attention. Group, kin, multi-level, and multi-trait selection including IGEs have all been shown to be highly effective in reducing mortality while increasing productivity of poultry layers and reduce or eliminate the need for beak trimming. Multi-level selection was shown to increases robustness as indicated by the greater ability of birds to cope with stressors. Kin selection has been shown to be easy to implement and improve both productivity and animal well-being. Management practices and rearing conditions employed for domestic animal production will continue to change based on ethical and scientific results. However, the animal breeding tools necessary to provide an animal that is best adapted to these changing conditions

  1. Using Next Generation Science Standards (NGSS) Practices to Address Scientific Misunderstandings Around Complex Environmental Issues

    NASA Astrophysics Data System (ADS)

    Turrin, M.; Kenna, T. C.

    2014-12-01

    The new NGSS provide an important opportunity for scientists to develop curriculum that links the practice of science to research-based data in order to improve understanding in areas of science that are both complex and confusing. Our curriculum focuses in particular on the fate and transport of anthropogenic radionuclides. Radioactivity, both naturally occurring and anthropogenic, is highly debated and largely misunderstood, and for large sections of the population is a source of scientific misunderstanding. Developed as part of the international GEOTRACES project which focuses on identifying ocean processes and quantifying fluxes that control the distributions of selected trace elements and isotopes in the ocean, and on establishing the sensitivity of these distributions to changing environmental conditions, the curriculum topic fits nicely into the applied focus of NGSS with both environmental and topical relevance. Our curriculum design focuses on small group discussion driven by questions, yet unlike more traditional curriculum pieces these are not questions posed to the students, rather they are questions posed by the students to facilitate their deeper understanding. Our curriculum design challenges the traditional question/answer memorization approach to instruction as we strive to develop an educational approach that supports the practice of science as well as the NGSS Cross Cutting Concepts and the Science & Engineering Practices. Our goal is for students to develop a methodology they can employ when faced with a complex scientific issue. Through background readings and team discussions they identify what type of information is important for them to know and where to find a reliable source for that information. Framing their discovery around key questions such as "What type of radioactive decay are we dealing with?", "What is the potential half-life of the isotope?", and "What are the pathways of transport of radioactivity?" allows students to evaluate a

  2. Langley's DEVELOP Team Applies NASA's Earth Observations to Address Environmental Issues Across the Country and Around the Globe

    NASA Technical Reports Server (NTRS)

    Childs, Lauren M.; Miller, Joseph E.

    2011-01-01

    The DEVELOP National Program was established over a decade ago to provide students with experience in the practical application of NASA Earth science research results. As part of NASA's Applied Sciences Program, DEVELOP focuses on bridging the gap between NASA technology and the public through projects that innovatively use NASA Earth science resources to address environmental issues. Cultivating a diverse and dynamic group of students and young professionals, the program conducts applied science research projects during three terms each year (spring, summer, and fall) that focus on topics ranging from water resource management to natural disasters.

  3. Hardware-in-the-loop environment facility to address pilot-vehicle-interface issues of a fighter aircraft

    NASA Astrophysics Data System (ADS)

    Pandurangareddy, Meenige

    2002-07-01

    The evolution of Pilot-Vehicle-Interface (PVI) of a fighter aircraft is a complex task. The PVI design involves both static and dynamic issues. Static issues involve the study of reach of controls and switches, ejection path clearance, readability of indicators and display symbols, etc. Dynamic issues involve the study of the effect of aircraft motion on display symbols, pilot emergency handling, situation awareness, weapon aiming, etc. This paper describes a method of addressing the above issues by building a facility with cockpit, which is ergonomically similar to the fighter cockpit. The cockpit is also fitted with actual displays, controls and switches. The cockpit is interfaced with various simulation models of aircraft and outside-window-image generators. The architecture of the facility is designed to represent the latencies of the aircraft and facilitates replacement of simulation models with actual units. A parameter injection facility could be used to induce faults in a comprehensive manner. Pilots could use the facility right from familiarising themselves with procedures to start the engine, take-off, navigate, aim the weapons, handling of emergencies and landing. This approach is being followed and further being enhanced on Cockpit-Environment-Facility (CEF) at Aeronautical Development Agency (ADA), Bangalore, India.

  4. Problems and Issues of Diversity in the United States.

    ERIC Educational Resources Information Center

    Naylor, Larry L., Ed.

    A number of social problems created by cultural diversity in the United States seem to defy resolution. The essays in this collection address some of these issues and are designed to initiate serious discussions on some of the most serious questions. The chapters are: (1) "Introduction to American Cultural Diversity: Unresolved Questions, Issues,…

  5. Patient and healthcare perspectives on the importance and efficacy of addressing spiritual issues within an interdisciplinary bone marrow transplant clinic: a qualitative study

    PubMed Central

    Sinclair, Shane; McConnell, Shelagh; Raffin Bouchal, Shelley; Ager, Naree; Booker, Reanne; Enns, Bert; Fung, Tak

    2015-01-01

    Objectives The purpose of this study was to use a qualitative approach to better understand the importance and efficacy of addressing spiritual issues within an interdisciplinary bone marrow transplant clinic from the perspectives of patients and healthcare providers. Setting Participants were recruited from the bone marrow transplant clinic of a large urban outpatient cancer care centre in western Canada. Participants: Focus groups were conducted with patients (n=7) and healthcare providers (n=9) to explore the importance of addressing spiritual issues across the treatment trajectory and to identify factors associated with effectively addressing these needs. Results Data were analysed using the qualitative approach of latent content analysis. Addressing spiritual issues was understood by patients and healthcare providers, as a core, yet under addressed, component of comprehensive care. Both sets of participants felt that addressing basic spiritual issues was the responsibility of all members of the interdisciplinary team, while recognising the need for specialised and embedded support from a spiritual care professional. While healthcare providers felt that the impact of the illness and treatment had a negative effect on patients’ spiritual well-being, patients felt the opposite. Skills, challenges, key time points and clinical indicators associated with addressing spiritual issues were identified. Conclusions Despite a number of conceptual and clinical challenges associated with addressing spiritual issues patients and their healthcare providers emphasised the importance of an integrated approach whereby basic spiritual issues are addressed by members of the interdisciplinary team and by an embedded spiritual care professional, who in addition also provides specialised support. The identification of clinical issues associated with addressing spiritual needs provides healthcare providers with clinical guidance on how to better integrate this aspect of care into

  6. Practical guidelines addressing ethical issues pertaining to the curation of human locus-specific variation databases (LSDBs)

    PubMed Central

    Povey, Sue; Al Aqeel, Aida I; Cambon-Thomsen, Anne; Dalgleish, Raymond; den Dunnen, Johan T; Firth, Helen V; Greenblatt, Marc S; Barash, Carol Isaacson; Parker, Michael; Patrinos, George P; Savige, Judith; Sobrido, Maria-Jesus; Winship, Ingrid; Cotton, Richard GH

    2010-01-01

    More than 1,000 Web-based locus-specific variation databases (LSDBs) are listed on the Website of the Human Genetic Variation Society (HGVS). These individual efforts, which often relate phenotype to genotype, are a valuable source of information for clinicians, patients, and their families, as well as for basic research. The initiators of the Human Variome Project recently recognized that having access to some of the immense resources of unpublished information already present in diagnostic laboratories would provide critical data to help manage genetic disorders. However, there are significant ethical issues involved in sharing these data worldwide. An international working group presents second-generation guidelines addressing ethical issues relating to the curation of human LSDBs that provide information via a Web-based interface. It is intended that these should help current and future curators and may also inform the future decisions of ethics committees and legislators. These guidelines have been reviewed by the Ethics Committee of the Human Genome Organization (HUGO). Hum Mutat 31:–6, 2010. © 2010 Wiley-Liss, Inc. PMID:20683926

  7. Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack

    SciTech Connect

    Stein, Steven L.; Lesperance, Ann M.; Upton, Jaki F.

    2010-02-01

    On October 9, 2008, federal, state and local policy makers, emergency managers, and medical and public health officials convened in Seattle, Washington, for a workshop on Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack. The day-long symposium was aimed at generating a dialogue about recovery and restoration through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems. The Principal Federal Official (PFO) provided an overview of the role of the PFO in a catastrophic event. A high-level summary of an anthrax scenario was presented. The remainder of the day was focused on interactive discussions among federal, state and local emergency management experts in the areas of: • Decision-making, prioritization, and command and control • Public health/medical services • Community resiliency and continuity of government. Key topics and issues that resulted from discussions included: • Local representation in the Joint Field Office (JFO) • JFO transition to the Long-Term Recovery Office • Process for prioritization of needs • Process for regional coordination • Prioritization - process and federal/military intervention • Allocation of limited resources • Re-entry decision and consistency • Importance of maintaining a healthy hospital system • Need for a process to establish a consensus on when it is safe to re-enter. This needs to be across all jurisdictions including the military. • Insurance coverage for both private businesses and individuals • Interaction between the government and industry. The symposium was sponsored by the Interagency Biological Restoration Demonstration, a collaborative regional program jointly funded by the U.S. Department of Homeland Security and the U.S. Department of Defense. To aid the program’s efforts and inform the development of blueprint for recovery from a biological incident

  8. What Is the Purpose of the Theses Addressing the Issue of Program Evaluation in Turkey? (The Case of Curriculum and Instruction: 1997-2015)

    ERIC Educational Resources Information Center

    Alkin-Sahin, Senar; Tunca, Nihal

    2016-01-01

    In the current study, the aim is to investigate the theses addressing the issue of program evaluation in the field of Curriculum and Instruction (C&I) in 1997-2015. The study employed the survey model. The universe of the study consists of totally 87 theses addressing the issue of program evaluation in the field of C&I in 1997-2015. As the…

  9. Unresolved issues in diagnosis and management of inherited bleeding disorders in the perinatal period: a White Paper of the Perinatal Task Force of the Medical and Scientific Advisory Council of the National Hemophilia Foundation, USA.

    PubMed

    Kulkarni, R; Ponder, K P; James, A H; Soucie, J M; Koerper, M; Hoots, W K; Lusher, J M

    2006-05-01

    Haemophilia and inherited bleeding disorders in newborns and their carrier mothers pose unique challenges. The pattern of bleeding and the causes and risk factors for bleeding are decidedly different than an older child or an adult with haemophilia/inherited bleeding disorder. This document outlines the needs for further research and education, summarizes the state of the art background information and provides guidance regarding research, education and access to care issues in this population.

  10. NATO and Hybrid Conflict: Unresolved Issues from the Past or Unresolvable Threats of the Present?

    DTIC Science & Technology

    2012-09-01

    ix LIST OF ACRONYMS AND ABBREVIATIONS ACO Allied Command Operations ACT Allied Command Transformation DC1 The Strategic Concept for the...understand the policies and mechanisms of NATO as well as the way the North-Atlantic community thinks and acts . I also want to thank Captain Scott Jasper who...command and control infrastructure, or a similar act of aggression against allied forces

  11. Fort Collins Science Center Ecosystem Dynamics branch--interdisciplinary research for addressing complex natural resource issues across landscapes and time

    USGS Publications Warehouse

    Bowen, Zachary H.; Melcher, Cynthia P.; Wilson, Juliette T.

    2013-01-01

    The Ecosystem Dynamics Branch of the Fort Collins Science Center offers an interdisciplinary team of talented and creative scientists with expertise in biology, botany, ecology, geology, biogeochemistry, physical sciences, geographic information systems, and remote-sensing, for tackling complex questions about natural resources. As demand for natural resources increases, the issues facing natural resource managers, planners, policy makers, industry, and private landowners are increasing in spatial and temporal scope, often involving entire regions, multiple jurisdictions, and long timeframes. Needs for addressing these issues include (1) a better understanding of biotic and abiotic ecosystem components and their complex interactions; (2) the ability to easily monitor, assess, and visualize the spatially complex movements of animals, plants, water, and elements across highly variable landscapes; and (3) the techniques for accurately predicting both immediate and long-term responses of system components to natural and human-caused change. The overall objectives of our research are to provide the knowledge, tools, and techniques needed by the U.S. Department of the Interior, state agencies, and other stakeholders in their endeavors to meet the demand for natural resources while conserving biodiversity and ecosystem services. Ecosystem Dynamics scientists use field and laboratory research, data assimilation, and ecological modeling to understand ecosystem patterns, trends, and mechanistic processes. This information is used to predict the outcomes of changes imposed on species, habitats, landscapes, and climate across spatiotemporal scales. The products we develop include conceptual models to illustrate system structure and processes; regional baseline and integrated assessments; predictive spatial and mathematical models; literature syntheses; and frameworks or protocols for improved ecosystem monitoring, adaptive management, and program evaluation. The descriptions

  12. Addressing Cultural Issues in an Organizational Context. Edited Conference Proceedings of the Teachers College Winter Roundtable (New York, New York, 1992).

    ERIC Educational Resources Information Center

    Johnson, Samuel D., Jr., Ed.; Carter, Robert T., Ed.

    Papers from this year's conference reflect the Roundtable's theme of addressing cultural issues in an organizational context. Topics cover a wide range of institutional and organizational issues in corporate, educational, and treatment settings. Papers include: (1) "The New Corporate Language for Race Relations" (keynote) (Clayton P.…

  13. Addressing Social Issues in the Classroom and Beyond: The Pedagogical Efforts of Pioneers in the Field. Research in Curriculum and Instruction

    ERIC Educational Resources Information Center

    Totten, Samuel, Ed.; Pedersen, Jon, Ed.

    2007-01-01

    Addressing Social Issues in the Classroom and Beyond: The Pedagogical Efforts of Pioneers in the Field is comprised of essays that delineate the genesis and evolution of the thought and work of pioneers in the field of social issues and education. The authors (many of whom, themselves, are noted professors of education and who have done…

  14. Innovative patient-centered skills training addressing challenging issues in cancer communications: Using patient's stories that teach.

    PubMed

    Bishop, Thomas W; Gorniewicz, James; Floyd, Michael; Tudiver, Fred; Odom, Amy; Zoppi, Kathy

    2016-05-01

    This workshop demonstrated the utility of a patient-centered web-based/digital Breaking Bad News communication training module designed to educate learners of various levels and disciplines. This training module is designed for independent, self-directed learning as well as group instruction. These interactive educational interventions are based upon video-recorded patient stories. Curriculum development was the result of an interdisciplinary, collaborative effort involving faculty from the East Tennessee State University (ETSU) Graduate Storytelling Program and the departments of Family and Internal Medicine at the James H. Quillen College of Medicine. The specific goals of the BBN training module are to assist learners in: (1) understanding a five-step patient-centered model that is based upon needs, preferences, and expectations of patients with cancer and (2) individualizing communication that is consistent with patient preferences in discussing emotions, informational detail, prognosis and timeline, and whether or not to discuss end-of-life issues. The pedagogical approach to the training module is to cycle through Emotional Engagement, Data, Modeled Practices, Adaptation Opportunities, and Feedback. The communication skills addressed are rooted in concepts found within the Reaching Common Ground communication training. A randomized control study investigating the effectiveness of the Breaking Bad News module found that medical students as well as resident physicians improved their communication skills as measured by an Objective Structured Clinical Examination. Four other similarly designed modules were also created: Living Through Treatment, Transitions: From Curable to Treatable/From Treatable to End-of-Life, Spirituality, and Family.

  15. Moon and Terrestrial Planets: Unresolved Questions

    NASA Astrophysics Data System (ADS)

    Schmitt, H. H.

    2002-12-01

    Human exploration during Apollo began the documentation of the evolution of the Moon and of its importance in understanding the origin and evolution of the terrestrial planets. This revolution in planetary geology continues as a vigorous and vibrant arena for discovery and debate for new generations of geoscientists. Although much has been learned and, indeed, resolved in lunar science, we are left with major questions unresolved. One fundamental question is that of the origin of the Moon. A large consensus has developed in the planetary science community that the Moon was created by the "giant impact" of a Mars-sized asteroid on the Earth after the accretion of the Earth was largely complete and differentiation had begun. A minority, however, questions this consensus hypothesis because of increasing indications that the lower mantle of the Moon may be largely undifferentiated. If the issue of the high angular momentum of the Earth-Moon system can be resolved through new modeling studies, then capture of a co-orbiting planetesimal may be an important alternative to a "giant impact". Another important question, particularly in consideration of the terrestrial and Martian surface environments during the first 0.8 billion years of Earth history, is the impact record of that period as recorded on the Moon. Again, a large consensus has developed that the 50 or so large and very large impact basins identified on the Moon were created over a very short "cataclysm" between about 3.9 and 3.8 billion years ago. Here also, a minority suggests that this period of large basin formation, although distinct in lunar history, took place over several hundred million years and that the apparent cataclysm is an artifact of sampling the effects of the last few basin-forming impacts. Either way, a previously unavailable source of impactors appeared somewhere in the solar system and greatly affected terrestrial environments at the time the precursors to life were appearing on Earth

  16. Overview of US AID-World Bank-NASA Collaboration to Address Water Management Issues in the MENA Region

    NASA Technical Reports Server (NTRS)

    Habib, Shahid

    2012-01-01

    The World Bank, USAID and NASA have recently established a joint project to study multiple issues pertaining to water related applications in the Middle East North Africa (MENA) region. The main concentration of the project is on utilization of remote sensing data and hydrological models to address crop irrigation and mapping, flood mapping and forecasting, evapotranspiration and drought problems prevalent in this large geographic area. Additional emphases are placed on understanding the climate impact on these areas as well. Per IPCC 2007 report, by the end of this century MENA region is projected to experience an increase of 3 C to 5 C rise in mean temperatures and a 20% decline in precipitation. This poses a serious problem for this geographic zone especially when majority of the hydrological consumption is for the agriculture sector and the remaining amount is for domestic consumption. The remote sensing data from space is one of the best ways to study such complex issues and further feed into the decision support systems. NASA's fleet of Earth Observing satellites offer a great vantage point from space to look at the globe and provide vital signs necessary to maintain healthy and sustainable ecosystem. These observations generate multiple products such as soil moisture, global precipitation, aerosols, cloud cover, normalized difference vegetation index, land cover/use, ocean altimetry, ocean salinity, sea surface winds, sea surface temperature, ozone and atmospheric gases, ice and snow measurements, and many more. All of the data products, models and research results are distributed-via the Internet freely through out the world. This project will utilize several NASA models such as global Land Data Assimilation System (LDAS) to generate hydrological states and fluxes in near real time. These LDAS products will then be further compared with other NASA satellite observations (MODIS, VIIRS, TRMM, etc.) and other discrete models to compare and optimize

  17. Addressing Impairment and Its Relationship to Professional Boundary Issues: A Response to Forrest, Elman, Gizara, and Vacha-Haase.

    ERIC Educational Resources Information Center

    Lamb, Douglas H.

    1999-01-01

    Responds to the Forrest et al article on counselor trainee impairment. Expands on several issues discussed in the article including evaluation and accreditation issues. Discusses professional boundaries as having relevance to anticipating and/or minimizing impairment. (Author/MKA)

  18. The phylogeny of mosses - addressing open issues with a new mitochondrial locus: group I intron cobi420.

    PubMed

    Wahrmund, Ute; Quandt, Dietmar; Knoop, Volker

    2010-02-01

    Mosses are an ancient clade of land plants, set apart from the two other monophyletic groups of bryophytes, the liverworts and the hornworts. Different molecular data sets seem to converge towards a consensus backbone phylogeny of mosses. Nevertheless, for some crucial nodes open questions remain, which obviously require additional phylogenetic information. We here report that a group I intron in the mitochondrial cob gene (cobi420) is universally conserved in the mosses, including basal genera such as Sphagnum and Takakia. Well resolved phylogenetic trees were obtained for 56 mosses of wide phylogenetic sampling, e.g. supporting a placement of Drummondia branching after the genera Timmiella and Catoscopium basal in the Dicranidae. Taxon gaps have been filled in the previously established data sets nad5i753, nad2i156, the nad5-nad4 intergenic region and chloroplast rbcL and rps4 genes. A concatenated 6-loci analysis suggests reconsideration of a Funariidae concept which includes Gigaspermaceae but leaves the isolated genus Timmia at the radiation of arthrodontous mosses unresolved.

  19. What Educators in Catholic Schools Might Expect when Addressing Gay and Lesbian Issues: A Study of Needs and Barriers

    ERIC Educational Resources Information Center

    Maher, Michael J.; Sever, Linda M.

    2007-01-01

    Previous research indicated that Catholic high schools in the United States were not addressing the topic of homosexuality in any significant and systematic way prior to the mid-1990s, though practitioners in Catholic high schools have begun to address the topic in recent years. This study, in sampling seven Catholic schools in the greater Chicago…

  20. Androgyny as Trait and as Role: Unresolved Issues.

    ERIC Educational Resources Information Center

    Spence, Janet T.

    In the late 1970's androgyny as a concept gained respectability, accompanied, however, by a backlash. Debate centered primarily on scientific grounds and both sides failed to define the concepts of masculinity, femininity and androgyny, including possible cultural relativity. Most empirical research on androgyny uses either the BSRI or the PAQ…

  1. Causal Indicator Models: Unresolved Issues of Construction and Evaluation

    ERIC Educational Resources Information Center

    West, Stephen G.; Grimm, Kevin J.

    2014-01-01

    These authors agree with Bainter and Bollen that causal effects represents a useful measurement structure in some applications. The structure of the science of the measurement problem should determine the model; the measurement model should not determine the science. They also applaud Bainter and Bollen's important reminder that the full…

  2. Sensitization to fungal allergens: Resolved and unresolved issues.

    PubMed

    Fukutomi, Yuma; Taniguchi, Masami

    2015-10-01

    Exposure and sensitization to fungal allergens can promote the development and worsening of allergic diseases. Although numerous species of fungi have been associated with allergic diseases in the literature, the significance of fungi from the genera Alternaria, Cladosporium, Penicillium, Aspergillus, and Malassezia has been well documented. However, it should be emphasized that the contribution of different fungal allergens to allergic diseases is not identical, but species-specific. Alternaria and Cladosporium species are considered to be important outdoor allergens, and sensitization and exposure to species of these genera is related to the development of asthma and rhinitis, as well as epidemics of asthma exacerbation, including life-threatening asthma exacerbation. In contrast, xerophilic species of Penicillium and Aspergillus, excluding Aspergillus fumigatus, are implicated in allergic diseases as indoor allergens. A. fumigatus has a high capacity to colonize the bronchial tract of asthmatic patients, causing severe persistent asthma and low lung function, and sometimes leading to allergic bronchopulmonary aspergillosis. Malassezia are common commensals of healthy skin, although they are also associated with atopic dermatitis, especially on the head and neck, but not with respiratory allergies. Despite its importance in the management of allergic diseases, precise recognition of species-specific IgE sensitization to fungal allergens is often challenging because the majority of fungal extracts exhibit broad cross-reactivity with taxonomically unrelated fungi. Recent progress in gene technology has contributed to the identification of specific and cross-reactive allergen components from different fungal sources. However, data demonstrating the clinical relevance of IgE reactivity to these allergen components are still insufficient.

  3. Unresolved Issues Concerning the Disposal of Stockpile Silver.

    DTIC Science & Technology

    1983-02-18

    that have occurred. We also interviewed a number of Federal officials and representatives of the domestic mining industry . Our review was performed in accordance with generally accepted government audit standards. (Author)

  4. Unresolved Issues With Inner Magnetosphere-Ionosphere Coupling

    NASA Technical Reports Server (NTRS)

    Gallagher, D. L.; Khazanov, G.

    2004-01-01

    Dipolarization and the release of stored magnetic energy is strongly evident in the energized plasma sheet electrons and ions injected earthward from the magnetotail. While some of these plasma are presumed lost into the dayside magnetosheath, much of the energy is dissipated into the ionosphere through electric currents, through collisions into low energy plasma, and into plasma waves, which then go on to heat and energize plasma of the inner magnetosphere. Many mechanisms for the transfer of energy and the consequences to inner magnetospheric plasma populations have been proposed. The sophistication of theoretical models to represent the interdependencies between plasma populations is rapidly increasing. However without the restraint and reality imposed on theory by relevant measurements, the degree to which specific mechanisms participate in the exchange of energy as a function of location and time cannot be known. ORBITALS offers this capability. Some of the outstanding problems in inner magnetospheric physics and the opportunities presented by the ORBITAL concept to solve problems will be discussed.

  5. Major unresolved issues in the formation of chondrules and CAIs

    NASA Technical Reports Server (NTRS)

    Wood, J. A.

    1994-01-01

    So much has been learned and published about chondrites and so many models have been floated (but neither proven nor refuted) that the subject has become extremely diffuse and amorphous. It is impossible to remain simultaneously aware of all the many constraints, from many different subdisciplines, that bear on nebular processes. This paper attempts to impose some structure on the situation and loosen the interpretational logjam by breaking the chondrite problem into a series of well-defined questions. Most are open questions; those that some might consider closed by now may deserve formal reexamination.

  6. Inclusion in Urban Educational Environments: Addressing Issues of Diversity, Equity, and Social Justice. Issues in the Research, Theory, Policy, and Practice of Urban Education

    ERIC Educational Resources Information Center

    Armstrong, Denise E.; McMahon, Brenda J.

    2006-01-01

    This book is motivated by the authors' experiences in working with students and their families in urban communities. They are particularly concerned about the urgent imperative to address the endemic educational and societal challenges that pervade the lives of urban students, particularly those who live in poverty, are of minority and immigrant…

  7. Insights into the Interactions between Educational Messages: Looking across Multiple Organizations Addressing Water Issues in Maricopa County, Arizona

    ERIC Educational Resources Information Center

    Cutts, Bethany; Saltz, Charlene; Elser, Monica

    2008-01-01

    The public receives environmental information from a variety of sources. Evaluation of a single program or one organization's effort is incomplete. Through surveys and interviews, we evaluate the cumulative impact of outreach by 20 water-related organizations in Maricopa County, Arizona. Household water conservation is a topic addressed by 18…

  8. The American Competitiveness Initiative: Addressing the STEM Teacher Shortage and Improving Student Academic Readiness. BHEF Issue Brief

    ERIC Educational Resources Information Center

    Business-Higher Education Forum (NJ1), 2006

    2006-01-01

    America's leaders are increasingly concerned about U.S. competitiveness in a rapidly globalizing world. In response, during the 2006 State of the Union Address, President Bush introduced the American Competitiveness Initiative (ACI) to promote policy that bolsters student achievement in the areas of science, technology, engineering, and…

  9. Race and Racism: The Efforts of Counseling Psychology to Understand and Address the Issues Associated With These Terms

    ERIC Educational Resources Information Center

    Casas, J. Manuel

    2005-01-01

    This paper focuses on race and racism with the underlying hope and expectation that in the near future the terms race and racism will be more accurately understood and, when necessary, more appropriately and selectively addressed by the field of counseling psychology. With respect to the term racism, it is hoped that the efforts of counseling…

  10. Poetry and Prose as Pedagogical Tools for Addressing Difficult Knowledges: Translocational Positionality and Issues of Collective Political Agency

    ERIC Educational Resources Information Center

    Keddie, Amanda

    2012-01-01

    In this paper the focus is on the possibilities that poetry and prose offer as pedagogical tools that can both accommodate and address difficult and painful knowledges. The paper presents and analyses poems and prose written by students at a non-traditional secondary school for disadvantaged girls (many of whom identify as Indigenous Australian).…

  11. Women Reaching Women: Change in Action--Using Action Learning to Help Address Seemingly Intractable and Large Scale Social Issues

    ERIC Educational Resources Information Center

    Langley, Dawn; Watts, Richard

    2010-01-01

    In 2008, 28 women from the Women's Institute volunteered to join us in a project exploring the issue of world poverty and gender inequality, specifically highlighting the disproportionate effects of climate change on women. Collectively we were asking a big question about how we as individuals, based in England, make a difference on a global…

  12. Face Values: The Use of Sensitive Error Correction to Address Adolescents' "Face" Issues in the Modern Languages Classroom

    ERIC Educational Resources Information Center

    Crichton, Hazel; Templeton, Brian; Valdera, Francisco

    2017-01-01

    Anxiety about "performing" in a foreign language in front of classmates may inhibit learners' contributions in the modern languages class through fear of embarrassment over possible error production. The issue of "face", perceived social standing in the eyes of others, presents a sensitive matter for young adolescents…

  13. Addressing healthcare.

    PubMed

    Daly, Rich

    2013-02-11

    Though President Barack Obama has rarely made healthcare references in his State of the Union addresses, health policy experts are hoping he changes that strategy this year. "The question is: Will he say anything? You would hope that he would, given that that was the major issue he started his presidency with," says Dr. James Weinstein, left, of the Dartmouth-Hitchcock health system.

  14. Is It More Important to Address the Issue of Patient Mobility or to Guarantee Universal Health Coverage in Europe?

    PubMed Central

    Legido-Quigley, Helena

    2016-01-01

    This paper discusses whether European institutions should devote so much attention and funding to cross-border healthcare or they should instead prioritise guaranteeing universal health coverage (UHC), “addressing inequalities” and tackling the effects of austerity measures. The paper argues through providing the evidence in both areas of research, that the priority at European level from a public health and social justice perspective should be to guarantee UHC for all the population living in Europe and prioritise protective action for those who are most in need. PMID:26673649

  15. Center for Strategic Leadership Issue Paper, August 2007, Volume 8-07. Military Education Workshop Addresses Threats to Stability and Security.

    DTIC Science & Technology

    2007-08-01

    support of partner countries to address such destabilizing issues as competition for scare resources, forced migration, food security, changing weather...upcoming National Intelligence Estimate (NIE), the National Inteligence Council (NIC) has reached out to a broad group of U.S. government organizations and...resource competition and conflict; water and food security; health and disease, and the stability of governments. The Army should be prepared to adapt

  16. Next Steps for Addressing EPA-Issued Step 2 Prevention of Significant Deterioration Greenhouse Gas Permits and Associated Requiremnts

    EPA Pesticide Factsheets

    This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Next Steps for Addressing EPA-Issued Step 2 Prevention of Significant Deterioration Greenhouse Gas Permits and Associated Requiremnts

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Open Skies Treaty imaging radar technology issues

    NASA Astrophysics Data System (ADS)

    Sandoval, M. B.

    1992-06-01

    This paper discusses the imaging radar technology requirements for the Open Skies regime, including the unresolved issues to be discussed at future Open Skies Consultative Commission (OSCC) meetings. Compliance with international rules on shared technology is addressed and some of the practical considerations for operational deployment of the radar imaging equipment in an Open Skies aircraft are presented. The Open Skies Treaty requirements and validation methodologies for imaging radars that were agreed on and those that will require future OSCC review are discussed.

  19. An approach to addressing ethical issues in a community-based risk assessment for HIV: a case from Chennai, India.

    PubMed

    Sivaram, Sudha; Srikrishnan, Aylur Kailasom; Murgavel, Kailapuri G; Mayer, Kenneth H; Anand, S; Celentano, David D; Solomon, Suniti

    2005-06-01

    Community-based assessment of HIV prevalence and behavioural risk factors is the basis for deciding priorities of prevention and care programmes. Here, upholding the human rights of participants in assessment is of utmost importance. The objective of the paper was to describe the process of implementation of an epidemiological survey to assess HIV-related behavioural and biological factors in Chennai city in South India and to suggest an ethical framework for conducting similar assessment activities in developing-country settings. A survey was conducted with participation from residents (n=1,659) of low-income urban communities (slums) as part of a community-based HIV/STD-prevention trial. Administration of the survey was preceded by extensive community contact and household visits to inform community members about the trial and assessment activities. Formative research further strengthened rapport with community, highlighted community concerns, and identified HIV-related risk behaviours that informed questionnaire design. The process of obtaining informed consent began before assessment activities and provided an opportunity for individuals to discuss participation with their families and friends. Privacy during assessment, comprehensive follow-up care for those who tested positive for HIV/STDs, such as nutritional and prevention counselling, referral services for opportunistic infections, and antenatal-care options for pregnant women increased trust and credibility of the project. The sustained availability of trial staff to facilitate access to resources to address non-HIV/STD-related felt-needs further strengthened participation of the community members. These resources included liaison services with local government to obtain public services, such as water and electricity and resources, to address concerns, such as alcohol abuse and domestic violence. Based on this experience, an ethical framework is suggested for conducting HIV epidemiological risk assessment

  20. Addressing System Integration Issues Required for the Developmente of Distributed Wind-Hydrogen Energy Systems: Final Report

    SciTech Connect

    Mann, M.D; Salehfar, H.; Harrison, K.W.; Dale, N.; Biaku, C.; Peters, A.J.; Hernandez-Pacheco: E.

    2008-04-01

    Wind generated electricity is a variable resource. Hydrogen can be generated as an energy storage media, but is costly. Advancements in power electronics and system integration are needed to make a viable system. Therefore, the long-term goal of the efforts at the University of North Dakota is to merge wind energy, hydrogen production, and fuel cells to bring emission-free and reliable power to commercial viability. The primary goals include 1) expand system models as a tool to investigate integration and control issues, 2) examine long-term effects of wind-electrolysis performance from a systematic perspective, and 3) collaborate with NREL and industrial partners to design, integrate, and quantify system improvements by implementing a single power electronics package to interface wild AC to PEM stack DC requirements. This report summarizes the accomplishments made during this project.

  1. Fostering youth leadership to address workplace and community environmental health issues: a university-school-community partnership.

    PubMed

    Delp, Linda; Brown, Marianne; Domenzain, Alejandra

    2005-07-01

    Many communities of color are disproportionately exposed to workplace and community environmental hazards. This article presents the results of a pilot project designed by a university-school-community partnership to develop youth leadership to confront these exposures. Using a popular empowerment education approach, students applied peer education, research, and organizing skills learned in the classroom to community-based internships in a service-learning model. Evaluation results from pretests and posttests, focus groups, and in-depth interviews demonstrated that students shared what they learned about young workers' rights and environmental justice with family and friends. They developed a critical analysis of environmental inequities, created a citywide youth coalition that advocates around legal, educational, and environmental issues affecting youth, and implemented campaigns to enforce child labor laws and to prevent school construction on contaminated land. This multifaceted model can serve as an important foundation to develop youth leaders to influence environmental policies in a variety of communities.

  2. Unresolved mourning, supernatural beliefs and dissociation: a mediation analysis.

    PubMed

    Thomson, Paula; Jaque, S Victoria

    2014-01-01

    Unresolved mourning is marked by disorganized behavior and states of mind. In this study, we speculated that pathological dissociation would mediate the effects of unresolved mourning on supernatural beliefs. This hypothesis was determined based on findings that indicate an association between higher levels of dissociation, stronger beliefs in the supernatural and unresolved mourning. We examined two groups of participants, one classified as non-unresolved (non-U) (n = 56) and the other as unresolved (n = 26) (U) with respect to past loss/trauma as measured by the Adult Attachment Interview (AAI). Two self-report instruments were administered to measure supernatural beliefs and dissociation. As hypothesized, the multivariate analysis of variance indicated mean differences between the two groups. The unresolved group had greater belief in the supernatural and more pathological dissociative processes. The mediation analysis demonstrated that pathological dissociation fully mediated the effects of unresolved mourning on supernatural beliefs.

  3. A Geographic Information-Assisted Temporal Mixture Analysis for Addressing the Issue of Endmember Class and Endmember Spectra Variability

    PubMed Central

    Li, Wenliang; Wu, Changshan

    2017-01-01

    Spectral mixture analysis (SMA) is a common approach for parameterizing biophysical fractions of urban environment and widely applied in many fields. For successful SMA, the selection of endmember class and corresponding spectra has been assumed as the most important step. Thanks to the spatial heterogeneity of natural and urban landscapes, the variability of endmember class and corresponding spectra has been widely considered as the profound error source in SMA. To address the challenging problems, we proposed a geographic information-assisted temporal mixture analysis (GATMA). Specifically, a logistic regression analysis was applied to analyze the relationship between land use/land covers and surrounding socio-economic factors, and a classification tree method was used to identify the present status of endmember classes throughout the whole study area. Furthermore, an ordinary kriging analysis was employed to generate a spatially varying endmember spectra at all pixels in the remote sensing image. As a consequence, a fully constrained temporal mixture analysis was conducted for examining the fractional land use land covers. Results show that the proposed GATMA achieved a promising accuracy with an RMSE of 6.81%, SE of 1.29% and MAE of 2.6%. In addition, comparative analysis result illustrates that a significant accuracy improvement has been found in the whole study area and both developed and less developed areas, and this demonstrates that the variability of endmember class and endmember spectra is essential for unmixing analysis. PMID:28335464

  4. The causality between smoking and lung cancer among groups and individuals: addressing issues in tobacco litigation in South Korea

    PubMed Central

    Khang, Young-Ho

    2015-01-01

    This article discusses issues on the causality between smoking and lung cancer, which have been raised during the tobacco litigation in South Korea. It should be recognized that the explanatory ability of risk factor(s) for inter-individual variations in disease occurrence is different from the causal contribution of the risk factor(s) to disease occurrence. The affected subjects of the tobacco litigation in South Korea are lung cancer patients with a history of cigarette smoking. Thus, the attributable fraction of the exposed rather than the population attributable fraction should be used in the tobacco litigation regarding the causal contribution of smoking to lung cancer. Scientific evidence for the causal relationship between smoking and lung cancer is based on studies of individuals and groups, studies in animals and humans, studies that are observational or experimental, studies in laboratories and communities, and studies in both underdeveloped and developed countries. The scientific evidence collected is applicable to both groups and individuals. The probability of causation, which is calculated based on the attributable fraction for the association between smoking and lung cancer, could be utilized as evidence to prove causality in individuals. PMID:26137845

  5. Addressing the Amorphous Content Issue in Quantitative Phase Analysis: The Certification of NIST Standard Reference Material 676a

    SciTech Connect

    J Cline; R Von Dreele; R Winburn; P Stephens; J Filliben

    2011-12-31

    A non-diffracting surface layer exists at any boundary of a crystal and can comprise a mass fraction of several percent in a finely divided solid. This has led to the long-standing issue of amorphous content in standards for quantitative phase analysis (QPA). NIST standard reference material (SRM) 676a is a corundum ({alpha}-Al{sub 2}O{sub 3}) powder, certified with respect to phase purity for use as an internal standard in powder diffraction QPA. The amorphous content of SRM 676a is determined by comparing diffraction data from mixtures with samples of silicon powders that were engineered to vary their specific surface area. Under the (supported) assumption that the thickness of an amorphous surface layer on Si was invariant, this provided a method to control the crystalline/amorphous ratio of the silicon components of 50/50 weight mixtures of SRM 676a with silicon. Powder diffraction experiments utilizing neutron time-of-flight and 25 keV and 67 keV X-ray energies quantified the crystalline phase fractions from a series of specimens. Results from Rietveld analyses, which included a model for extinction effects in the silicon, of these data were extrapolated to the limit of zero amorphous content of the Si powder. The certified phase purity of SRM 676a is 99.02% {+-} 1.11% (95% confidence interval). This novel certification method permits quantification of amorphous content for any sample of interest, by spiking with SRM 676a.

  6. Addressing the amorphous content issue in quantitative phase analysis: the certification of NIST standard reference material 676a.

    PubMed

    Cline, James P; Von Dreele, Robert B; Winburn, Ryan; Stephens, Peter W; Filliben, James J

    2011-07-01

    A non-diffracting surface layer exists at any boundary of a crystal and can comprise a mass fraction of several percent in a finely divided solid. This has led to the long-standing issue of amorphous content in standards for quantitative phase analysis (QPA). NIST standard reference material (SRM) 676a is a corundum (α-Al(2)O(3)) powder, certified with respect to phase purity for use as an internal standard in powder diffraction QPA. The amorphous content of SRM 676a is determined by comparing diffraction data from mixtures with samples of silicon powders that were engineered to vary their specific surface area. Under the (supported) assumption that the thickness of an amorphous surface layer on Si was invariant, this provided a method to control the crystalline/amorphous ratio of the silicon components of 50/50 weight mixtures of SRM 676a with silicon. Powder diffraction experiments utilizing neutron time-of-flight and 25 keV and 67 keV X-ray energies quantified the crystalline phase fractions from a series of specimens. Results from Rietveld analyses, which included a model for extinction effects in the silicon, of these data were extrapolated to the limit of zero amorphous content of the Si powder. The certified phase purity of SRM 676a is 99.02% ± 1.11% (95% confidence interval). This novel certification method permits quantification of amorphous content for any sample of interest, by spiking with SRM 676a.

  7. Addressing Work-Related Issues in Medical Rehabilitation: Revision of an Online Information Tool for Healthcare Professionals

    PubMed Central

    Wolf, Hans-Dieter; Gerlich, Christian; Vogel, Heiner; Neuderth, Silke

    2016-01-01

    Background. Medical rehabilitation increasingly considers occupational issues as determinants of health and work ability. Information on work-related rehabilitation concepts should therefore be made available to healthcare professionals. Objective. To revise a website providing healthcare professionals in medical rehabilitation facilities with information on work-related concepts in terms of updating existing information and including new topics, based on recommendations from implementation research. Method. The modification process included a questionnaire survey of medical rehabilitation centers (n = 28); two workshops with experts from rehabilitation centers, health payers, and research institutions (n = 14); the selection of new topics and revision of existing text modules based on expert consensus; and an update of good practice descriptions of work-related measures. Results. Health payers' requirements, workplace descriptions, and practical implementation aids were added as new topics. The database of good practice examples was extended to 63 descriptions. Information on introductory concepts was rewritten and supplemented by current data. Diagnostic tools were updated by including additional assessments. Conclusions. Recommendations from implementation research such as assessing user needs and including expert knowledge may serve as a useful starting point for the dissemination of information on work-related medical rehabilitation into practice. Web-based information tools such as the website presented here can be quickly adapted to current evidence and changes in medicolegal regulations. PMID:27610246

  8. Automatic Spectral Classification of Unresolved Binary Stars

    NASA Astrophysics Data System (ADS)

    Weaver, W. B.

    2000-12-01

    An artificial neural network (ANN) technique has been developed to perform two-dimensional classification of the components of binary stars of any temperature or luminosity classifications. Using 15 Angstrom-resolution spectra, a single ANN can classify the unresolved components with an average accuracy of 2.5 subclasses in temperature and about 0.45 classes in luminostiy for up to 3 magnitudes difference in luminosity. The use of two ANNs, the first providing coarse classification while the second provides specialist classification, reduces the mean absolute errors to about 0.5 subclasses in temperature and 0.33 classes in luminosity. The system operates with no human intervention except initial wavelength registration and can classify about 20 binaries per second on a Pentium-class computer. This research was supported by the Friends of MIRA.

  9. Interactive efforts to address DSM and IRP issues: Findings from the first year of a two-year study

    SciTech Connect

    Schweitzer, M. ); English, M.; Altman, J. . Energy, Environment and Resources Center); Yourstone, E. )

    1993-04-01

    This report presents findings from the first year of a two-year study of interactive efforts involving utilities and non-utility parties (NUPS) working together to prepare plans, develop Demand-Side Management (DSM) programs, or otherwise promote integrated planning and the use of cost-effective DSM measures. Of the ten cases covered in the current study, seven involved the collaborative approach to NUP involvement, which generally is marked by intensive utility-NUP interactions designed to reach consensus on a broad range of important issues; in collaboratives, outside consultants often are provided to enhance the technical capabilities of the NUPS. Another of the cases in this study involved a cooperative arrangement,'' whereby a utility and a NLT worked together in a focused short-term effort to develop a single DSM program. The intense interaction involved in this approach makes it very similar to a collaborative, except that both the scope and the duration of the effort were much more limited than in a normal collaborative. The ninth case concerned a task force run by state regulatory staff that was charged with the limited job of studying various cost-effectiveness tests available for assessing prospective DSM measures. All of these approaches (collaborative, cooperative arrangement, and task force) are types of interactive effort, as that term is used in this report. The final case concerned NUPs' attempts to encourage greater utility use of DSM in Florida but, to date, no interactive effort has been initiated there. Three main features of interactive efforts are described in this report: (1) the participants involved; (2) the context in which the efforts took place; and (3) key characteristics of the interactive process. This report also examines the outcomes achieved by the interactive efforts. These outcomes can be divided into two general categories: Product-related and participant-related.

  10. Interactive efforts to address DSM and IRP issues: Findings from the first year of a two-year study

    SciTech Connect

    Schweitzer, M.; English, M.; Altman, J.; Yourstone, E.

    1993-04-01

    This report presents findings from the first year of a two-year study of interactive efforts involving utilities and non-utility parties (NUPS) working together to prepare plans, develop Demand-Side Management (DSM) programs, or otherwise promote integrated planning and the use of cost-effective DSM measures. Of the ten cases covered in the current study, seven involved the collaborative approach to NUP involvement, which generally is marked by intensive utility-NUP interactions designed to reach consensus on a broad range of important issues; in collaboratives, outside consultants often are provided to enhance the technical capabilities of the NUPS. Another of the cases in this study involved a ``cooperative arrangement,`` whereby a utility and a NLT worked together in a focused short-term effort to develop a single DSM program. The intense interaction involved in this approach makes it very similar to a collaborative, except that both the scope and the duration of the effort were much more limited than in a normal collaborative. The ninth case concerned a task force run by state regulatory staff that was charged with the limited job of studying various cost-effectiveness tests available for assessing prospective DSM measures. All of these approaches (collaborative, cooperative arrangement, and task force) are types of interactive effort, as that term is used in this report. The final case concerned NUPs` attempts to encourage greater utility use of DSM in Florida but, to date, no interactive effort has been initiated there. Three main features of interactive efforts are described in this report: (1) the participants involved; (2) the context in which the efforts took place; and (3) key characteristics of the interactive process. This report also examines the outcomes achieved by the interactive efforts. These outcomes can be divided into two general categories: Product-related and participant-related.

  11. Real-time earthquake alert system for the greater San Francisco Bay Area: a prototype design to address operational issues

    SciTech Connect

    Harben, P.E.; Jarpe, S.; Hunter, S.

    1996-12-10

    The purpose of the earthquake alert system (EAS) is to outrun the seismic energy released in a large earthquake using a geographically distributed network of strong motion sensors that telemeter data to a rapid CPU-processing station, which then issues an area-wide warning to a region before strong motion will occur. The warning times involved are short, from 0 to 30 seconds or so; consequently, most responses must be automated. The San Francisco Bay Area is particularly well suited for an EAS because (1) large earthquakes have relatively shallow hypocenters (10- to 20-kilometer depth), giving favorable ray-path geometries for larger warning times than deeper from earthquakes, and (2) the active faults are few in number and well characterized, which means far fewer geographically distributed strong motion sensors are (about 50 in this region). An EAS prototype is being implemented in the San Francisco Bay Area. The system consists of four distinct subsystems: (1) a distributed strong motion seismic network, (2) a central processing station, (3) a warning communications system and (4) user receiver and response systems. We have designed a simple, reliable, and inexpensive strong motion monitoring station that consists of a three-component Analog Devices ADXLO5 accelerometer sensing unit, a vertical component weak motion sensor for system testing, a 16-bit digitizer with multiplexing, and communication output ports for RS232 modem or radio telemetry. The unit is battery-powered and will be sited in fire stations. The prototype central computer analysis system consists of a PC dam-acquisition platform that pipes the incoming strong motion data via Ethernet to Unix-based workstations for dam processing. Simple real-time algorithms, particularly for magnitude estimation, are implemented to give estimates of the time since the earthquake`s onset its hypocenter location, its magnitude, and the reliability of the estimate. These parameters are calculated and transmitted

  12. Addressing end of life care issues in a tertiary treatment centre: lessons learned from surveying parents' experiences.

    PubMed

    Midson, Rosie; Carter, Bernie

    2010-03-01

    Much of the work in children's hospitals is rightly focused on treatments aimed towards cure but this means that death is often seen as a failure and, as such, it may not be discussed or acknowledged as a possibility until very late in a child's stay in hospital. However, this reluctance can deny the child and their family the opportunity to be informed, prepare and make choices. A survey of the care received by parents whose child had died in a children's tertiary treatment centre led to a greater understanding of the parents' experiences and the ways in which care could be enhanced. Parents talked of the way in which the geography of the hospital could be disruptive and dislocating and yet they often had no place to be alone or in private. Communication was identified as a core issue with many parents being positive about the quality and timing of communication. However, other parents expressed a preference for more preparation about the possibility that their child might die. Some parents had positive experiences of follow-up visits after their child's death, whilst others remained frustrated and some felt this visit had made them re-live the experiences. The importance of kind, supportive and consistent care was clearly evidenced by the parents when they spoke about their feelings and emotions. The findings helped to develop and implement an End of Life Care Pathway and a pathway tool which aimed to enhance parents' experiences and to improve care. A further survey was triggered by the concern that the pathway was not being fully utilized and it became apparent that, despite the tool, staff were still reluctant to provide anticipatory guidance, even though many practical aspects of care scored well. The need for good communication that prepares parents for the eventuality that their child might or will die is one of the clearest lessons from the second survey. This is important as anticipatory guidance opens up parents - and children's - choices, and their

  13. Addressing health care market reform through an insurance exchange: essential policy components, the public plan option, and other issues to consider.

    PubMed

    Fronstin, Paul; Ross, Murray N

    2009-06-01

    HEALTH INSURANCE EXCHANGE: This Issue Brief examines issues related to managed competition and the use of a health insurance exchange for the purpose of addressing cost, quality, and access to health care services. It discusses issues that must be addressed when designing an exchange in order to reform the health insurance market and also examines state efforts at health reform that use an exchange. RISK VS. PRICE COMPETITION: The basic component of managed competition is the creation an organized marketplace that brings together health insurers and consumers (either as individuals or through their employers). The sponsor of the exchange would set "rules of engagement" for participating insurers and offer consumers a menu of choices among different plans. Ultimately, the goal of a health insurance exchange is to shift the market from competition based on risk to competition based on price and quality. ADVERSE SELECTION AND AFFORDABILITY: Among the issues that need to be addressed if an exchange that uses managed competition has a realistic chance of reducing costs, improving quality, and expanding coverage: Everyone needs to be in the risk pool, with individuals required to purchase insurance or face significant financial consequences; effective risk adjustment is essential to eliminate risk selection as an insurance business model--forcing competition on costs and quality; the insurance benefit must be specific and clear--without standards governing cost sharing, covered services, and network coverage there is no way to assess whether a requirement to purchase or issue coverage has been met; and subsidies would be necessary for low-income individuals to purchase insurance. THE PUBLIC PLAN OPTION: The public plan option is shaping up to be one of the most contentious issues in the health reform debate. Proponents also believe of a public plan is necessary to drive private insurers toward true competition. Opponents view it as a step toward government-run health

  14. Using the PACE EH model to mobilize communities to address local environmental health issues--a case study in Island County, Washington.

    PubMed

    Higman, Keith; Servatius, Celine; Webber, Whitney L; McDonald, Tim

    2007-01-01

    The Island County Environmental Health Initiative (ICEHI) is a demonstration project in the use of the Protocol for Assessing Community Excellence in Environmental Health (PACE EH) to build capacity in the 10 essential services of environmental health. The PACE EH methodology systematically applies the 10 essential services of environmental health through the completion of 13 tasks derived from a community-based environmental health assessment process. The ICEHI has successfully engaged community members, identified environmental health issues important to the community, and led to the implementation of action plans aimed at reducing environmental health risks through use of community resources. This paper describes the methodology utilized by the ICEHI to address locally important environmental health issues so that other local and state environmental health agencies may replicate the process in their communities.

  15. Strategies and recommendations for addressing forest health issues in the Blue Mountains of Oregon and Washington. Forest service general technical report

    SciTech Connect

    Tanaka, J.A.; Starr, G.L.; Quigley, T.M.

    1995-03-01

    The Blue Mountains Natural Resources Institute held three types of meetings to obtain public and scientific input into strategies for addressing forest health issues in the Blue Mountains of Oregon and Washington. Seven strategies are proposed: (2) plan and implement management on a landscape level, (2) enhance training on natural resources, (3) facilitate public involvement in planning and decision making, (4) develop an integrated landscape-level database, (5) develop an integrated monitoring system, (6) assess economic and social effects and assist with adaptation to change, and (7) identify barriers to improving the protesting forest health and recommend changes.

  16. Strategies to Address Recruiting and Retention Issues in the Military (Strategies pour aborder les questions de recrutement et de fidelisation dans les armees)

    DTIC Science & Technology

    2009-10-01

    Oct 2009 Strategies to Address Recruiting and Retention Issues in the Military (Stratégies pour aborder les questions de recrutement et de...les questions de recrutement et de fidélisation dans les armées) The material in this publication was assembled to support a Special Course under...HFM-180 Stratégies pour aborder les questions de recrutement et de fidélisation dans les armées (RTO-EN-HFM-180) Synthèse L’objectif des

  17. Addressing Mental Health Disparities through Clinical Competence Not Just Cultural Competence: The Need for Assessment of Sociocultural Issues in the Delivery of Evidence-Based Psychosocial Rehabilitation Services

    PubMed Central

    Yamada, Ann-Marie; Brekke, John S

    2008-01-01

    Recognition of ethnic/racial disparities in mental health services has not directly resulted in the development of culturally responsive psychosocial interventions. There remains a fundamental need for assessment of sociocultural issues that have been linked with the expectations, needs, and goals of culturally diverse consumers with severe and persistent mental illness. The authors posit that embedding the assessment of sociocultural issues into psychosocial rehabilitation practice is one step in designing culturally relevant empirically supported practices. It becomes a foundation on which practitioners can examine the relevance of their interventions to the diversity encountered in everyday practice. This paper provides an overview of the need for culturally and clinically relevant assessment practices and asserts that by improving the assessment of sociocultural issues the clinical competence of service providers is enhanced. The authors offer a conceptual framework for linking clinical assessment of sociocultural issues to consumer outcomes and introduce an assessment tool adapted to facilitate the process in psychosocial rehabilitation settings. Emphasizing competent clinical assessment skills will ultimately offer a strategy to address disparities in treatment outcomes for understudied populations of culturally diverse consumers with severe and persistent mental illness. PMID:18778881

  18. Addressing Phonological Questions with Ultrasound

    ERIC Educational Resources Information Center

    Davidson, Lisa

    2005-01-01

    Ultrasound can be used to address unresolved questions in phonological theory. To date, some studies have shown that results from ultrasound imaging can shed light on how differences in phonological elements are implemented. Phenomena that have been investigated include transitional schwa, vowel coalescence, and transparent vowels. A study of…

  19. Unresolved velocity structure in diffuse interstellar clouds

    NASA Technical Reports Server (NTRS)

    Black, John H.; Van Dishoeck, Ewine F.

    1988-01-01

    Recent high-resolution observations of interstellar absorption lines of CH and CN toward Zeta Oph obtained by Crane et al. (1986), and Palazzi et al. (1988), exhibit line widths that suggest thermal line broadening at high temperature, T about 1200 K. Observations of CO line emission at 2.6 mm toward Zeta Oph (Langer et al.,1987) indicate that the molecular gas resides in four distinct velocity components that span less than 3 km/s in Doppler velocity. Simulated CH and CN absorption line profiles are compared for high-temperature (T = 1200 K) thermal broadening and for a combination of low-temperature (T = 50 K) thermal plus turbulent broadening. It is shown that the two broadening models reproduce existing observations comparably well and are virtually indistinguishable at a lambda/Delta-lambda ratio of about 100,000. The observed differences in the CH and CN line widths may reflect slightly different distributions of those molecules along the line of sight. The simulations use very recent, improved laboratory spectroscopic data on CH (Bernath). Some related consequences of such unresolved velocity structure on the ultraviolet absorption lines of CO are examined. Indirect diagnostics of temperature in the Zeta Oph cloud favor low-temperature thermal plus turbulent broadening, and the implied rate of dissipation of turbulence is in harmony with estimates of the global input of mechanical energy into to interstellar medium.

  20. Unresolved questions regarding human hereditary deafness.

    PubMed

    Rehman, A U; Friedman, T B; Griffith, A J

    2016-06-04

    Human hearing loss is a common neurosensory disorder about which many basic research and clinically relevant questions are unresolved. This review on hereditary deafness focuses on three examples considered at first glance to be uncomplicated, however, upon inspection, are enigmatic and ripe for future research efforts. The three examples of clinical and genetic complexities are drawn from studies of (i) Pendred syndrome/DFNB4 (PDS, OMIM 274600), (ii) Perrault syndrome (deafness and infertility) due to mutations of CLPP (PRTLS3, OMIM 614129), and (iii) the unexplained extensive clinical variability associated with TBC1D24 mutations. At present, it is unknown how different mutations of TBC1D24 cause non-syndromic deafness (DFNB86, OMIM 614617), epilepsy (OMIM 605021), epilepsy with deafness, or DOORS syndrome (OMIM 220500) that is characterized by deafness, onychodystrophy (alteration of toenail or fingernail morphology), osteodystrophy (defective development of bone), mental retardation, and seizures. A comprehensive understanding of the multifaceted roles of each gene associated with human deafness is expected to provide future opportunities for restoration as well as preservation of normal hearing.

  1. Rural Health Issues. Keynote Address.

    ERIC Educational Resources Information Center

    Hart, Gary

    Medical students that come from rural areas are more likely to return to rural areas to practice, but rural students apply for medical school at half the rate of urban students. Factors that contribute to this problem are the lack of rural representation on medical school selection committees; centralization of medical education facilities in…

  2. Unresolved Grief and Continuing Bonds: An Attachment Perspective

    ERIC Educational Resources Information Center

    Field, Nigel P.

    2006-01-01

    Much of the contemporary bereavement literature on the continuing bond to the deceased (CB) has emphasized its adaptiveness and given limited attention to when it may be maladaptive. The attachment literature on disorganized-unresolved attachment classification in relation to loss, or "unresolved loss," is informative in identifying CB expressions…

  3. Enhancing capacities of riparian professionals to address and resolve transboundary issues in international river basins: experiences from the Lower Mekong River Basin

    NASA Astrophysics Data System (ADS)

    Douven, W.; Mul, M. L.; Fernández-Álvarez, B.; Hung, S. Lam; Bakker, N.; Radosevich, G.; van der Zaag, P.

    2012-09-01

    This paper analyses the design and impact of capacity building programmes aimed at enhancing capacities of riparian professionals to address and resolve transboundary issues in international river basins. The case study is a programme developed by the Mekong River Commission (MRC). A post-training evaluation was applied to assess its impact in terms of individual capacity enhancement and change (use and application of knowledge, factors hampering application, and change in function and opportunities within the organisation). The design of the Capacity Building Programme of the MRC Flood Management and Mitigation Programme required a well balanced range of subjects (such as IWRM (integrated water resources management), model and decision support systems, and international water law). The post-training evaluation, 6 months after the last training workshop, showed an increase in familiarity with the topics for all 37 respondents, with the highest increase for the respondents with few years of working experience and from training and education institutions. The relevance of the subjects taught was highlighted by 95% of the respondents, and 78% of the participants had already used some of the acquired knowledge in their job. The respondents indicated that they did not have sufficient opportunities to apply all knowledge. The phased implementation and training of lecturers during the training workshops had a good impact, directly through increasing involvement in facilitation and delivery of the capacity building programme and through the use of the knowledge gained in short courses and development of curricula at their institute. For these types of capacity building programmes, a few recommendations can be made. The selection of participants is crucial for the application of the learned knowledge in their work. The integrative nature of transboundary water issues calls for a capacity building programme addressing a wide range of subjects, which can be understood by a

  4. Enhancing capacities of riparian professionals to address and resolve transboundary issues in international river basins: experiences from the Lower Mekong River Basin

    NASA Astrophysics Data System (ADS)

    Douven, W.; Mul, M. L.; Álvarez, B. F.; Son, L. H.; Bakker, N.; Radosevich, G.; van der Zaag, P.

    2012-03-01

    This paper analyses the design and impact of capacity building programmes aimed at enhancing capacities of riparian professionals to address and resolve transboundary issues in international river basins. Case study is a programme developed by the Mekong River Commission (MRC). A post training evaluation was applied to assess its impact in terms of individual capacity enhancement and change (use and application of knowledge, factors hampering application, and change in function and opportunities within their organisation). The design of the Capacity Building Programme of the MRC Flood Management and Mitigation Programme showed a well balanced range of subjects (such as IWRM, models and decision support systems and international water law) which are required for such an integrated topic. The post training evaluation, 6 months after the last training workshop, showed the increase in familiarity of the topics for all 37 respondents, with highest increase for the respondents with few years of working experience and from training and educational institutions. The relevance of the subjects taught is shown by the fact that 95% of the respondents indicated they saw the relevance of the subjects and 78% had already used some knowledge acquired in their job. The respondents also indicated that they did not have sufficient opportunities to apply all knowledge acquired. The phased implementation and training of lecturers during the training workshops, had a good impact, directly through increasing involvement in facilitation and delivery of the capacity building programme and through the use of the knowledge gained in short courses and development of curricula at their training institute. For these types of capacity building programmes, a few recommendations can be made. The selection of participants is crucial for the application of the learned knowledge in their work. The integrative nature of transboundary water issues calls for a capacity building programme addressing a

  5. Multiaxial Creep-Fatigue and Creep-Ratcheting Failures of Grade 91 and Haynes 230 Alloys Toward Addressing Design Issues of Gen IV Nuclear Power Plants

    SciTech Connect

    Hassan, Tasnim; Lissenden, Cliff; Carroll, Laura

    2015-04-01

    The proposed research will develop systematic sets of uniaxial and multiaxial experimental data at a very high temperature (850-950°C) for Alloy 617. The loading histories to be prescribed in the experiments will induce creep-fatigue and creep-ratcheting failure mechanisms. These experimental responses will be scrutinized in order to quantify the influences of temperature and creep on fatigue and ratcheting failures. A unified constitutive model (UCM) will be developed and validated against these experimental responses. The improved UCM will be incorporated into the widely used finite element commercial software packages ANSYS. The modified ANSYS will be validated so that it can be used for evaluating the very high temperature ASME-NH design-by-analysis methodology for Alloy 617 and thereby addressing the ASME-NH design code issues.

  6. Synthesizing Nanomaterials for Energy Applications: Probing Activity as a Function of Composition, Morphology and Purity to Address Key Issues Associated with Fuel Cells and Li-Ion Batteries

    NASA Astrophysics Data System (ADS)

    Scofield, Megan Elaine

    With the growing need to find alternative clean energy sources to fossil fuels, research into developing efficient fuel cells and batteries stands at the forefront of this grand effort. However, before mass commercialization, fundamental key issues need to be addressed. For example, fuel cells are subject to high catalyst costs and poor durability of the underlying carbon support. As a way to alleviate these issues, we have synthesized ultrathin one-dimensional (1D) alloy nanowires to probe the effect of composition, purity, and one-dimensionality upon the observed overall activity, performance, and durability. In terms of chemical composition, crystalline ultrathin PtM alloy nanowires (NWs) ('M' = Fe, Co, Ru, Cu, and Au) were generated and subsequently evaluated for the hydrogen oxidation reaction (HOR). Additionally, ternary-based catalysts were synthesized (PtRuFe) in order to analyze how chemical composition influences CO tolerance as well as methanol oxidation reaction (MOR) and formic acid oxidation reaction (FAOR) activities. In both cases, we utilized a sustainably mild, ambient wet-synthesis method for the fabrication of chemically pure and crystalline systems in order to fabricate ultrathin, homogeneous alloy NWs. Moreover, in these studies, our NW systems exhibit favorable synergistic electronic effects with respect to controls. To address another fundamental issue associated with the durability of fuel cells, we have synthesized various metal oxide and perovskite materials of different sizes and chemical compositions as supports for Pt nanoparticles (NPs). Specifically, we have demonstrated favorable metal support interactions between the Pt NPs and the SrRuO3 NP supports, which lead to increased MOR activity as compared with not only the other metal oxide supports tested but also the commercial Pt NP/C standard. In terms of Li-ion batteries, LiFePO4 materials have become increasingly popular as a cathode material due to the many benefits they possess

  7. Further development of a robust workup process for solution-phase high-throughput library synthesis to address environmental and sample tracking issues.

    PubMed

    Kuroda, Noritaka; Hird, Nick; Cork, David G

    2006-01-01

    During further improvement of a high-throughput, solution-phase synthesis system, new workup tools and apparatus for parallel liquid-liquid extraction and evaporation have been developed. A combination of in-house design and collaboration with external manufacturers has been used to address (1) environmental issues concerning solvent emissions and (2) sample tracking errors arising from manual intervention. A parallel liquid-liquid extraction unit, containing miniature high-speed magnetic stirrers for efficient mixing of organic and aqueous phases, has been developed for use on a multichannel liquid handler. Separation of the phases is achieved by dispensing them into a newly patented filter tube containing a vertical hydrophobic porous membrane, which allows only the organic phase to pass into collection vials positioned below. The vertical positioning of the membrane overcomes the hitherto dependence on the use of heavier-than-water, bottom-phase, organic solvents such as dichloromethane, which are restricted due to environmental concerns. Both small (6-mL) and large (60-mL) filter tubes were developed for parallel phase separation in library and template synthesis, respectively. In addition, an apparatus for parallel solvent evaporation was developed to (1) remove solvent from the above samples with highly efficient recovery and (2) avoid the movement of individual samples between their collection on a liquid handler and registration to prevent sample identification errors. The apparatus uses a diaphragm pump to achieve a dynamic circulating closed system with a heating block for the rack of 96 sample vials and an efficient condenser to trap the solvents. Solvent recovery is typically >98%, and convenient operation and monitoring has made the apparatus the first choice for removal of volatile solvents.

  8. How agro-ecological research helps to address food security issues under new IPM and pesticide reduction policies for global crop production systems.

    PubMed

    E Birch, A Nicholas; Begg, Graham S; Squire, Geoffrey R

    2011-06-01

    Drivers behind food security and crop protection issues are discussed in relation to food losses caused by pests. Pests globally consume food estimated to feed an additional one billion people. Key drivers include rapid human population increase, climate change, loss of beneficial on-farm biodiversity, reduction in per capita cropped land, water shortages, and EU pesticide withdrawals under policies relating to 91/414 EEC. IPM (Integrated Pest Management) will be compulsory for all EU agriculture by 2014 and is also being widely adopted globally. IPM offers a 'toolbox' of complementary crop- and region-specific crop protection solutions to address these rising pressures. IPM aims for more sustainable solutions by using complementary technologies. The applied research challenge now is to reduce selection pressure on single solution strategies, by creating additive/synergistic interactions between IPM components. IPM is compatible with organic, conventional, and GM cropping systems and is flexible, allowing regional fine-tuning. It reduces pests below economic thresholds utilizing key 'ecological services', particularly biocontrol. A recent global review demonstrates that IPM can reduce pesticide use and increase yields of most of the major crops studied. Landscape scale 'ecological engineering', together with genetic improvement of new crop varieties, will enhance the durability of pest-resistant cultivars (conventional and GM). IPM will also promote compatibility with semiochemicals, biopesticides, precision pest monitoring tools, and rapid diagnostics. These combined strategies are urgently needed and are best achieved via multi-disciplinary research, including complex spatio-temporal modelling at farm and landscape scales. Integrative and synergistic use of existing and new IPM technologies will help meet future food production needs more sustainably in developed and developing countries, in an era of reduced pesticide availability. Current IPM research gaps are

  9. Attachment stability and the emergence of unresolved representations during adolescence.

    PubMed

    Aikins, Julie Wargo; Howes, Carollee; Hamilton, Claire

    2009-09-01

    This 15-year longitudinal study examined the stability of attachment representations from infancy to adolescence and investigated the emergence of unresolved representations during adolescence in a sample of 47 16-year-olds. Attachment was assessed at 12 months using the Strange Situation Procedure, at 4 years using the modified Strange Situation Procedure, and again at 16 years with the Adult Attachment Projective (AAP). The emergence of unresolved classifications in adolescence (AAP) was associated with higher rates of negative life events, low levels of early mother-child relationship security (an aggregate measure of the 12-month and 4-year measures), negative teacher-child relationship experiences in middle childhood, and low early adolescent friendship quality. The results support the growing body of evidence suggesting that changes in attachment are lawful, while adding to the growing understanding of the emergence of unresolved attachment representations.

  10. The Platte River - High Plains Aquifer (PR-HPA) Long Term Agroecosystem Research (LTAR) Network - Data and Technological Resources to Address Current and Emerging Issues in Agroecosystems.

    NASA Astrophysics Data System (ADS)

    Okalebo, J. A.; Wienhold, B.; Suyker, A.; Erickson, G.; Hayes, M. J.; Awada, T.

    2015-12-01

    The Platte River - High Plains Aquifer (PR-HPA) is one of 18 established Long Term Agroecosystem Research (LTAR) networks across the US. PR-HPA is a partnership between the Institute of Agriculture and Natural Resources at the University of Nebraska-Lincoln (UNL), the USDA-ARS Agroecosystem Management Research Unit (AMRU) in Lincoln, and the USDA-ARS Environmental Management Research Unit (EMRU) in Clay Center, NE. The PR-HPA network encompasses 27,750 ha of research sites with data going back to the early 1900s. A partial list of on-going research projects include those encompassing long-term manuring and continuous corn (Est. 1912), dryland tillage plots (Est. 1970), soil nutrients and tillage (Est. 1983), biofuel feedstock studies (Est. 2001), and carbon sequestration study (Est. 2000). Affiliated partners include the National Drought Mitigation Center (NDMC) that develops measures to improve preparedness and adaptation to climate variability and drought; the High Plains Regional Climate Center (HPRCC) that coordinates data acquisition from over 170 automated weather stations and around 50 automated soil moisture network across NE and beyond; the AMERIFLUX and NEBFLUX networks that coordinate the water vapor and carbon dioxide flux measurements across NE with emphasis on rainfed and irrigated crop lands; the ARS Greenhouse gas Reduction through Agricultural Carbon Enhancement network (GRACEnet) and the Resilient Economic Agricultural Practices (REAP) project; and the Center for Advanced Land Management Information Technologies (CALMIT) that assists with the use of geospatial technologies for agriculture and natural resource applications. Current emphases are on addressing present-day and emerging issues related to profitability and sustainability of agroecosystems. The poster will highlight some of the ongoing and planned efforts in research pertaining to climate variability and change, water sustainability, and ecological and agronomic challenges associated

  11. Comprehensive Lifecycle Planning and Management System For Addressing Water Issues Associated With Shale Gas Development In New York, Pennsylvania, And West Virginia

    SciTech Connect

    Arthur, J. Daniel

    2012-07-01

    The objective of this project is to develop a modeling system to allow operators and regulators to plan all aspects of water management activities associated with shale gas development in the target project area of New York, Pennsylvania, and West Virginia (target area ), including water supply, transport, storage, use, recycling, and disposal and which can be used for planning, managing, forecasting, permit tracking, and compliance monitoring. The proposed project is a breakthrough approach to represent the entire shale gas water lifecycle in one comprehensive system with the capability to analyze impacts and options for operational efficiency and regulatory tracking and compliance, and to plan for future water use and disposition. It will address all of the major water-related issues of concern associated with shale gas development in the target area, including water withdrawal, transport, storage, use, treatment, recycling, and disposal. It will analyze the costs, water use, and wastes associated with the available options, and incorporate constraints presented by permit requirements, agreements, local and state regulations, equipment and material availability, etc. By using the system to examine the water lifecycle from withdrawals through disposal, users will be able to perform scenario analysis to answer "what if" questions for various situations. The system will include regulatory requirements of the appropriate state and regional agencies and facilitate reporting and permit applications and tracking. These features will allow operators to plan for more cost effective resource production. Regulators will be able to analyze impacts of development over an entire area. Regulators can then make informed decisions about the protections and practices that should be required as development proceeds. This modeling system will have myriad benefits for industry, government, and the public. For industry, it will allow planning all water management operations for a

  12. Challenging the One-Way Paradigm for More Effective Science Communication: A Critical Review of Two Public Campaigns Addressing Contentious Environmental Issues

    ERIC Educational Resources Information Center

    McEntee, Marie; Mortimer, Claire

    2013-01-01

    This article examines two large-scale public communication campaigns to explore the appropriateness and effectiveness of using one-way communication in contentious environmental issues. The findings show while one-way communication can be successfully employed in contentious issues, it is not appropriate for all contexts and may contribute to…

  13. Ensemble Kalman filters for dynamical systems with unresolved turbulence

    SciTech Connect

    Grooms, Ian; Lee, Yoonsang; Majda, Andrew J.

    2014-09-15

    Ensemble Kalman filters are developed for turbulent dynamical systems where the forecast model does not resolve all the active scales of motion. Coarse-resolution models are intended to predict the large-scale part of the true dynamics, but observations invariably include contributions from both the resolved large scales and the unresolved small scales. The error due to the contribution of unresolved scales to the observations, called ‘representation’ or ‘representativeness’ error, is often included as part of the observation error, in addition to the raw measurement error, when estimating the large-scale part of the system. It is here shown how stochastic superparameterization (a multiscale method for subgridscale parameterization) can be used to provide estimates of the statistics of the unresolved scales. In addition, a new framework is developed wherein small-scale statistics can be used to estimate both the resolved and unresolved components of the solution. The one-dimensional test problem from dispersive wave turbulence used here is computationally tractable yet is particularly difficult for filtering because of the non-Gaussian extreme event statistics and substantial small scale turbulence: a shallow energy spectrum proportional to k{sup −5/6} (where k is the wavenumber) results in two-thirds of the climatological variance being carried by the unresolved small scales. Because the unresolved scales contain so much energy, filters that ignore the representation error fail utterly to provide meaningful estimates of the system state. Inclusion of a time-independent climatological estimate of the representation error in a standard framework leads to inaccurate estimates of the large-scale part of the signal; accurate estimates of the large scales are only achieved by using stochastic superparameterization to provide evolving, large-scale dependent predictions of the small-scale statistics. Again, because the unresolved scales contain so much energy

  14. New Approaches to the Parameterization of Gravity-Wave and Flow-Blocking Drag due to Unresolved Mesoscale Orography Guided by Mesoscale Model Predictability Research

    DTIC Science & Technology

    2012-09-30

    and Flow-Blocking Drag due to Unresolved Mesoscale Orography Guided by Mesoscale Model Predictability Research Stephen D. Eckermann Geospace ...5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Geospace Science & Technology Branch

  15. Patterns of drug distribution: implications and issues.

    PubMed

    Johnson, Bruce D

    2003-01-01

    This article delineates various patterns of illicit sales of drugs, especially at the retail (and near-retail) level, addressing a variety of central issues about drug sales and distribution documented during the past 30 years. including: a) the links between drug consumption and drug distribution activities; b) the various distribution roles; c) various levels of the distribution hierarchy; d) types of retail and wholesale markets; e) the association of drug distribution with nondrug associated criminality and violence. The article also will address the implications of drug distribution: whether various public policies such as supply reduction and source interdiction affect illicit drug markets, and how policing strategies and various law enforcement strategies can influence the involvement of individual participation in drug distribution activities. The overlooked contribution of treatment for "drug abuse" to reducing drug sales and distribution activities also will be considered as will other critical unresolved issues.

  16. Patterns of Drug Distribution: Implications and Issues#

    PubMed Central

    Johnson, Bruce D.

    2007-01-01

    This article delineates various patterns of illicit sales of drugs, especially at the retail (and near-retail) level, addressing a variety of central issues about drug sales and distribution documented during the past 30 years, including: a) the links between drug consumption and drug distribution activities; b) the various distribution roles; c) various levels of the distribution hierarchy; d) types of retail and wholesale markets; e) the association of drug distribution with nondrug associated criminality and violence. The article also will address the implications of drug distribution: whether various public policies such as supply reduction and source interdiction affect illicit drug markets, and how policing strategies and various law enforcement strategies can influence the involvement of individual participation in drug distribution activities. The overlooked contribution of treatment for “drug abuse” to reducing drug sales and distribution activities also will be considered as will other critical unresolved issues. PMID:14582578

  17. Recommended Changes to the No Child Left Behind Act to Address Workforce Issues. Submitted to the House Subcommittee on Higher Education, Lifelong Learning, and Competitiveness of the Committee on Education and Labor

    ERIC Educational Resources Information Center

    Harris, Linda; Tsoi-A-Fatt, Rhonda

    2007-01-01

    This paper presents Center for Law and Social Policy's (CLASP's) recommendations on how No Child Left Behind (NCLB) could better address the workforce challenges faced by this country. CLASP is a nonprofit organization engaged in research, analysis, technical assistance, and advocacy on a range of issues affecting low-income families. The…

  18. Not Yes or No, But What If: An Examination of Policies and Issues to be Addressed with Open Homosexuality in the US Military

    DTIC Science & Technology

    2009-04-01

    Dont ask, dont tell. Gay rights organizations argue that it is a human rights issue and cite several countries that have lifted the ban on open...don’t tell.” Gay rights organizations argue that it is a human rights issue and cite several countries that have lifted the ban on open homosexuality...Barrack Obama as the forty-fourth President of the United States, the countries’ gay rights groups are looking to finally reap the rewards of their

  19. Addressing Racism

    ERIC Educational Resources Information Center

    Journal for Research in Mathematics Education, 2013

    2013-01-01

    This dialogue, extracted from a conversation among some members of the Equity Special Issue Editorial Panel, concerns racism in mathematics education. It raises issues about the use of various terms; about fields of research outside of mathematics education; and about the kinds of racialization processes that occur for students, teachers, and…

  20. Religious Congregations' Collaborations: With Whom Do They Work and What Resources Do They Share in Addressing HIV and Other Health Issues?

    ERIC Educational Resources Information Center

    Werber, Laura; Derose, Kathryn Pitkin; Dominguez, Blanca X.; Mata, Michael A.

    2012-01-01

    This study explores how religious congregations interact with other community organizations to address health and, in particular, HIV-related needs within their membership and/or local communities. Case study data from a diverse sample of 14 urban congregations (6 Black, 4 Latino, 2 White, and 2 mixed race-ethnicity) indicate that they engaged in…

  1. The Design and Evaluation of a Teaching-Learning Sequence Addressing the Solubility Concept with Turkish Secondary School Students. Special Issue

    ERIC Educational Resources Information Center

    Kabapinar, Filiz; Leach, John; Scott, Phil

    2004-01-01

    This paper reports upon a study addressing teaching and learning about solubility to Turkish first-year secondary school students (age 14-15). The principal aim of the research was to investigate the impact on students' understanding of solubility, of introducing a simple particle model of matter. A teaching intervention to fit within the existing…

  2. The Real Controversy about Child Sexual Abuse Research: Contradictory Findings and Critical Issues Not Addressed by Rind, Tromovitch, and Bauserman in Their 1998 Outcomes Meta-Analysis.

    ERIC Educational Resources Information Center

    Tice, Pamela Paradis; Whittenburg, John A.; Baker, Gail L.; Lemmey, Dorothy E.

    2001-01-01

    Presents a review of all types of child sexual abuse research ignored by Rind, Tromovitch, and Bauserman in their 1998 meta-analytic study. Eight major findings are addressed. Altogether these findings demonstrate the narrow focus of the meta-analysis. By restricting a broad meta-analysis to only some of the research and population in question,…

  3. Chopsticks Don't Make It Culturally Competent: Addressing Larger Issues for HIV Prevention among Gay, Bisexual, and Queer Asian Pacific Islander Men

    ERIC Educational Resources Information Center

    Han, Chong-suk

    2009-01-01

    According to the Centers for Disease Control and Prevention, men who have sex with men account for the largest proportion of cumulative AIDS cases among Asian Pacific Islanders. Yet little is known about the factors that need to be addressed in developing culturally competent intervention strategies for members of this group. This article explores…

  4. Mothers’ Unresolved Trauma Blunts Amygdala Response to Infant Distress

    PubMed Central

    Kim, Sohye; Fonagy, Peter; Allen, Jon; Strathearn, Lane

    2014-01-01

    While the neurobiology of post-traumatic stress disorder has been extensively researched, much less attention has been paid to the neural mechanisms underlying more covert but pervasive types of trauma (e.g., those involving disrupted relationships and insecure attachment). Here, we report on a neurobiological study documenting that mothers’ attachment-related trauma, when unresolved, undermines her optimal brain response to her infant’s distress. We examined the amygdala blood oxygenation level-dependent response in 42 first-time mothers as they underwent functional magnetic resonance imaging scanning, viewing happy and sad face images of their own infant, along with those of a matched unknown infant. Whereas mothers with no trauma demonstrated greater amygdala responses to the sad faces of their own infant as compared to their happy faces, mothers who were classified as having unresolved trauma in the Adult Attachment Interview (Dynamic Maturational Model) displayed blunted amygdala responses when cued by their own infants’ sadness as compared to happiness. Unknown infant faces did not elicit differential amygdala responses between the mother groups. The blunting of the amygdala response in traumatized mothers is discussed as a neural indication of mothers’ possible disengagement from infant distress, which may be part of a process linking maternal unresolved trauma and disrupted maternal caregiving. PMID:24635646

  5. Project 10 Handbook: Addressing Lesbian and Gay Issues in Our Schools. A Resource Directory for Teachers, Guidance Counselors, Parents and School-Based Adolescent Care Providers. Third Edition.

    ERIC Educational Resources Information Center

    Friends of Project 10, Inc.

    This handbook was developed by Project 10, an on-campus counseling program within the Los Angeles (California) Unified School District. The handbook covers many of the issues and problems that arise for homosexual high school students. Introductory material includes a history of the informal beginnings of Project 10. The first chapter describes…

  6. Looking beyond first-world problems: an emerging global workplace is encouraging more biomedical engineers to address the health issues of the developing world.

    PubMed

    Tucker, Lindsay

    2014-01-01

    Each year, the developed world is flooded with complex new medical technologies, from robotic prosthetics to remote-controlled aspirin implants. Meanwhile, only about 10% of health research funds are spent addressing the pressing problems of developing nations, although these countries make up 93% of the worldwide burden of disease. In short, while a small fraction of the world pops brand-name pharmaceuticals, the majority suffers from poor sanitation, contaminated drinking water, preventable disease, and child mortality.

  7. Micronutrients in pregnancy: current knowledge and unresolved questions.

    PubMed

    Berti, C; Biesalski, H K; Gärtner, R; Lapillonne, A; Pietrzik, K; Poston, L; Redman, C; Koletzko, B; Cetin, I

    2011-12-01

    Micronutrient status is increasingly recognized to play an important role in the health and well-being of pregnant women and in the development and long-term health of the offspring. On 26th - 28th February 2009, The Child Health Foundation invited leading experts in this area to a scientific workshop at Obergurgl, Austria to review and critically discuss current knowledge, to identify issues that may need to be addressed in future recommendations, and to highlight priorities and opportunities for future research. This report summarizes updated key conclusions of the workshop with regards to micronutrients' intake and physiological role related to mother, placenta and fetus, as well as relevance for adverse pregnancy and long-term outcomes.

  8. Keynote Address.

    ERIC Educational Resources Information Center

    Gardner, Howard

    1999-01-01

    Discusses four issues related to music: (1) music as a form of intelligence and the misconceptions that have arisen; (2) music as a discipline focusing on mastering the discipline of music and obstacles to musicality; (3) a rationale for music education; and (4) the future of music education. (CMK)

  9. New probability table treatment in MCNP for unresolved resonances

    SciTech Connect

    Carter, L.L.; Little, R.C.; Hendricks, J.S.; MacFarlane, R.E.

    1998-04-01

    An upgrade for MCNP has been implemented to sample the neutron cross sections in the unresolved resonance range using probability tables. These probability tables are generated with the cross section processor code NJOY, by using the evaluated statistical information about the resonances to calculate cumulative probability distribution functions for the microscopic total cross section. The elastic, fission, and radiative capture cross sections are also tabulated as the average values of each of these partials conditional upon the value of the total. This paper summarizes how the probability tables are utilized in this MCNP upgrade and compares this treatment with the approximate smooth treatment for some example problems.

  10. Managing for biodiversity unresolved science and policy questions

    SciTech Connect

    Westman, W.E. )

    1990-01-01

    A discussion is presented of efficient strategies for species preservationin spite of continued human alteration of the environment. Current policy and unresolved questions are included in the discussion. Incentives to maintain seminatural areas as a conservation strategy are recommended: planting of hedgerows or windbreaks to provide corridors for migration of species during climate change; purchase of development rights of natural and seminatural land for conversion to park reserves when climate stabilizes; use of intercropping, traditional forest gardens and crop plantings in the tropics; and maintenance of seminatural habitats on public and private lands.

  11. A computer program for analyzing unresolved Mossbauer hyperfine spectra

    NASA Technical Reports Server (NTRS)

    Schiess, J. R.; Singh, J. J.

    1978-01-01

    The program for analyzing unresolved Mossbauer hyperfine spectra was written in FORTRAN 4 language for the Control Data CYBER 170 series digital computer system with network operating system 1.1. With the present dimensions, the program requires approximately 36,000 octal locations of core storage. A typical case involving two innermost coordination shells in which the amplitudes and the peak positions of all three components were estimated in 25 iterations requires 30 seconds on CYBER 173. The program was applied to determine the effects of various near neighbor impurity shells on hyperfine fields in dilute FeAl alloys.

  12. Academic Institutions and One Health: Building Capacity for Transdisciplinary Research Approaches to Address Complex Health Issues at the Animal–Human–Ecosystem Interface

    PubMed Central

    Allen-Scott, Lisa K.; Buntain, Bonnie; Hatfield, Jennifer M.; Meisser, Andrea

    2015-01-01

    To improve health at the human, animal, and ecosystem interface, defined as One Health, training of researchers must transcend individual disciplines to develop a new process of collaboration. The transdisciplinary research approach integrates frameworks and methodologies beyond academic disciplines and includes involvement of and input from policy makers and members of the community. The authors argue that there should be a significant shift in academic institutions’ research capacity to achieve the added value of a transdisciplinary approach for addressing One Health problems. This Perspective is a call to action for academic institutions to provide the foundations for this salient shift. The authors begin by describing the transdisciplinary approach, propose methods for building transdisciplinary research capacity, and highlight three value propositions that support the case. Examples are provided to illustrate how the transdisciplinary approach to research adds value through improved sustainability of impact, increased cost-effectiveness, and enhanced abilities to mitigate potentially harmful unintended consequences. The authors conclude with three key recommendations for academic institutions: (1) a focus on creating enabling environments for One Health and transdisciplinary research, (2) the development of novel funding structures for transdisciplinary research, and (3) training of “transmitters” using real-world-oriented educational programs that break down research silos through collaboration across disciplines. PMID:25650827

  13. Academic Institutions and One Health: Building Capacity for Transdisciplinary Research Approaches to Address Complex Health Issues at the Animal-Human-Ecosystem Interface.

    PubMed

    Allen-Scott, Lisa K; Buntain, Bonnie; Hatfield, Jennifer M; Meisser, Andrea; Thomas, Christopher James

    2015-07-01

    To improve health at the human, animal, and ecosystem interface, defined as One Health, training of researchers must transcend individual disciplines to develop a new process of collaboration. The transdisciplinary research approach integrates frameworks and methodologies beyond academic disciplines and includes involvement of and input from policy makers and members of the community. The authors argue that there should be a significant shift in academic institutions' research capacity to achieve the added value of a transdisciplinary approach for addressing One Health problems. This Perspective is a call to action for academic institutions to provide the foundations for this salient shift. The authors begin by describing the transdisciplinary approach, propose methods for building transdisciplinary research capacity, and highlight three value propositions that support the case. Examples are provided to illustrate how the transdisciplinary approach to research adds value through improved sustainability of impact, increased cost-effectiveness, and enhanced abilities to mitigate potentially harmful unintended consequences. The authors conclude with three key recommendations for academic institutions: (1) a focus on creating enabling environments for One Health and transdisciplinary research, (2) the development of novel funding structures for transdisciplinary research, and (3) training of "transmitters" using real-world-oriented educational programs that break down research silos through collaboration across disciplines.

  14. Addressing the Interface Issues in All-Solid-State Bulk-Type Lithium Ion Battery via an All-Composite Approach.

    PubMed

    Chen, Ru-Jun; Zhang, Yi-Bo; Liu, Ting; Xu, Bing-Qing; Lin, Yuan-Hua; Nan, Ce-Wen; Shen, Yang

    2017-03-22

    All-solid-state bulk-type lithium ion batteries (LIBs) are considered ultimate solutions to the safety issues associated with conventional LIBs using flammable liquid electrolyte. The development of bulk-type all-solid-state LIBs has been hindered by the low loading of active cathode materials, hence low specific surface capacity, and by the high interface resistance, which results in low rate and cyclic performance. In this contribution, we propose and demonstrate a synergistic all-composite approach to fabricating flexible all-solid-state LIBs. PEO-based composite cathode layers (filled with LiFePO4 particles) of ∼300 μm in thickness and composite electrolyte layers (filled with Al-LLZTO particles) are stacked layer-by-layer with lithium foils as negative layer and hot-pressed into a monolithic all-solid-state LIB. The flexible LIB delivers a high specific discharge capacity of 155 mAh/g, which corresponds to an ultrahigh surface capacity of 10.8 mAh/cm(2), exhibits excellent capacity retention up to at least 10 cycles and could work properly under harsh operating conditions such as bending or being sectioned into pieces. The all-composite approach is favorable for improving both mesoscopic and microscopic interfaces inside the all-solid-state LIB and may provide a new toolbox for design and fabrication of all-solid-state LIBs.

  15. Chemistry on the mesoscale: Modeling and measurement issues

    NASA Technical Reports Server (NTRS)

    Thompson, Anne; Pleim, John; Walcek, Christopher; Ching, Jason; Binkowski, Frank; Tao, Wei-Kuo; Dickerson, Russell; Pickering, Kenneth

    1993-01-01

    The topics covered include the following: Regional Acid Deposition Model (RADM) -- a coupled chemistry/mesoscale model; convection in RADM; unresolved issues for mesoscale modeling with chemistry -- nonprecipitating clouds; unresolved issues for mesoscale modeling with chemistry -- aerosols; tracer studies with Goddard Cumulus Ensemble Model (GCEM); field observations of trace gas transport in convection; and photochemical consequences of convection.

  16. Space Station Engineering Design Issues

    NASA Technical Reports Server (NTRS)

    Mcruer, Duane T.; Boehm, Barry W.; Debra, Daniel B.; Green, C. Cordell; Henry, Richard C.; Maycock, Paul D.; Mcelroy, John H.; Pierce, Chester M.; Stafford, Thomas P.; Young, Laurence R.

    1989-01-01

    Space Station Freedom topics addressed include: general design issues; issues related to utilization and operations; issues related to systems requirements and design; and management issues relevant to design.

  17. Issues in Training Family Scientists.

    ERIC Educational Resources Information Center

    Ganong, Lawrence H.; And Others

    1995-01-01

    Issues related to graduate education in family science, especially at the doctoral level, are explored. Discusses competencies family scientists should have, as well as experiences necessary to help students acquire them. Proposes ideas for a core curriculum, identifies controversies and unresolved issues, and examines training for the future.…

  18. Inaugural address

    NASA Astrophysics Data System (ADS)

    Joshi, P. S.

    2014-03-01

    From jets to cosmos to cosmic censorship P S Joshi Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India E-mail: psj@tifr.res.in 1. Introduction At the outset, I should like to acknowledge that part of the title above, which tries to capture the main flavour of this meeting, and has been borrowed from one of the plenary talks at the conference. When we set out to make the programme for the conference, we thought of beginning with observations on the Universe, but then we certainly wanted to go further and address deeper questions, which were at the very foundations of our inquiry, and understanding on the nature and structure of the Universe. I believe, we succeeded to a good extent, and it is all here for you in the form of these Conference Proceedings, which have been aptly titled as 'Vishwa Mimansa', which could be possibly translated as 'Analysis of the Universe'! It is my great pleasure and privilege to welcome you all to the ICGC-2011 meeting at Goa. The International Conference on Gravitation and Cosmology (ICGC) series of meetings are being organized by the Indian Association for General Relativity and Gravitation (IAGRG), and the first such meeting was planned and conducted in Goa in 1987, with subsequent meetings taking place at a duration of about four years at various locations in India. So, it was thought appropriate to return to Goa to celebrate the 25 years of the ICGC meetings. The recollections from that first meeting have been recorded elsewhere here in these Proceedings. The research and teaching on gravitation and cosmology was initiated quite early in India, by V V Narlikar at the Banares Hindu University, and by N R Sen in Kolkata in the 1930s. In course of time, this activity grew and gained momentum, and in early 1969, at the felicitation held for the 60 years of V V Narlikar at a conference in Ahmedabad, P C Vaidya proposed the formation of the IAGRG society, with V V Narlikar being the first President. This

  19. Convocation address.

    PubMed

    Kakodkar, A

    1999-07-01

    This convocation addressed by Dr. Anil Kakodkar focuses on the challenges faced by graduating students. In his speech, he emphasized the high level of excellence achieved by the industrial sector; however, he noted that there has been a loss of initiative in maximizing value addition, which was worsened by an increasing population pressure. In facing a stiff competition in the external and domestic markets, it is imperative to maximize value addition within the country in a competitive manner and capture the highest possible market share. To achieve this, high-quality human resources are central. Likewise, family planning programs should become more effective and direct available resources toward national advantage. To boost the domestic market, he suggests the need to search for strengths to achieve leadership position in those areas. First, an insight into the relationship between the lifestyles and the needs of our people and the natural resource endowment must be gained. Second, remodeling of the education system must be undertaken to prepare the people for adding the necessary innovative content in our value addition activities. Lastly, Dr. Kakodkar emphasizes the significance of developing a strong bond between parents and children to provide a sound foundation and allow the education system to grow upon it.

  20. Opening Address

    NASA Astrophysics Data System (ADS)

    Yamada, T.

    2014-12-01

    Ladies and Gentlemen, it is my great honor and pleasure to present an opening address of the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3). On the behalf of the organizing committee, I certainly welcome all your visits to KGU Kannai Media Center belonging to Kanto Gakuin University, and stay in Yokohama. In particular, to whom come from abroad more than 17 countries, I would appreciate your participations after long long trips from your homeland to Yokohama. The first international workshop on "State of the Art in Nuclear Cluster Physics", called SOTANCP, was held in Strasbourg, France, in 2008, and the second one was held in Brussels, Belgium, in 2010. Then the third workshop is now held in Yokohama. In this period, we had the traditional 10th cluster conference in Debrecen, Hungary, in 2012. Thus we have the traditional cluster conference and SOTANCP, one after another, every two years. This obviously shows our field of nuclear cluster physics is very active and flourishing. It is for the first time in about 10 years to hold the international workshop on nuclear cluster physics in Japan, because the last cluster conference held in Japan was in Nara in 2003, about 10 years ago. The president in Nara conference was Prof. K. Ikeda, and the chairpersons were Prof. H. Horiuchi and Prof. I. Tanihata. I think, quite a lot of persons in this room had participated at the Nara conference. Since then, about ten years passed. So, this workshop has profound significance for our Japanese colleagues. The subjects of this workshop are to discuss "the state of the art in nuclear cluster physics" and also discuss the prospect of this field. In a couple of years, we saw significant progresses of this field both in theory and in experiment, which have brought better and new understandings on the clustering aspects in stable and unstable nuclei. I think, the concept of clustering has been more important than ever. This is true also in the

  1. Presidential address.

    PubMed

    Vohra, U

    1993-07-01

    The Secretary of India's Ministry of Health and Family Welfare serves as Chair of the Executive Council of the International Institute for Population Sciences in Bombay. She addressed its 35th convocation in 1993. Global population stands at 5.43 billion and increases by about 90 million people each year. 84 million of these new people are born in developing countries. India contributes 17 million new people annually. The annual population growth rate in India is about 2%. Its population size will probably surpass 1 billion by the 2000. High population growth rates are a leading obstacle to socioeconomic development in developing countries. Governments of many developing countries recognize this problem and have expanded their family planning programs to stabilize population growth. Asian countries that have done so and have completed the fertility transition include China, Japan, Singapore, South Korea, and Thailand. Burma, Malaysia, North Korea, Sri Lanka, and Vietnam have not yet completed the transition. Afghanistan, Bangladesh, Iran, Nepal, and Pakistan are half-way through the transition. High population growth rates put pressure on land by fragmenting finite land resources, increasing the number of landless laborers and unemployment, and by causing considerable rural-urban migration. All these factors bring about social stress and burden civic services. India has reduced its total fertility rate from 5.2 to 3.9 between 1971 and 1991. Some Indian states have already achieved replacement fertility. Considerable disparity in socioeconomic development exists among states and districts. For example, the states of Bihar, Madhya Pradesh, Rajasthan, and Uttar Pradesh have female literacy rates lower than 27%, while that for Kerala is 87%. Overall, infant mortality has fallen from 110 to 80 between 1981 and 1990. In Uttar Pradesh, it has fallen from 150 to 98, while it is at 17 in Kerala. India needs innovative approaches to increase contraceptive prevalence rates

  2. Welcome Address

    NASA Astrophysics Data System (ADS)

    Kiku, H.

    2014-12-01

    Ladies and Gentlemen, It is an honor for me to present my welcome address in the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3), as the president of Kanto Gakuin University. Particularly to those from abroad more than 17 countries, I am very grateful for your participation after long long trips from your home to Yokohama. On the behalf of the Kanto Gakuin University, we certainly welcome your visit to our university and stay in Yokohama. First I would like to introduce Kanto Gakuin University briefly. Kanto Gakuin University, which is called KGU, traces its roots back to the Yokohama Baptist Seminary founded in 1884 in Yamate, Yokohama. The seminary's founder was Albert Arnold Bennett, alumnus of Brown University, who came to Japan from the United States to establish a theological seminary for cultivating and training Japanese missionaries. Now KGU is a major member of the Kanto Gakuin School Corporation, which is composed of two kindergartens, two primary schools, two junior high schools, two senior high schools as well as KGU. In this university, we have eight faculties with graduate school including Humanities, Economics, Law, Sciences and Engineering, Architecture and Environmental Design, Human and Environmental Studies, Nursing, and Law School. Over eleven thousands students are currently learning in our university. By the way, my major is the geotechnical engineering, and I belong to the faculty of Sciences and Engineering in my university. Prof. T. Yamada, here, is my colleague in the same faculty. I know that the nuclear physics is one of the most active academic fields in the world. In fact, about half of the participants, namely, more than 50 scientists, come from abroad in this conference. Moreover, I know that the nuclear physics is related to not only the other fundamental physics such as the elementary particle physics and astrophysics but also chemistry, medical sciences, medical cares, and radiation metrology

  3. Addressing hypertext design and conversion issues

    NASA Technical Reports Server (NTRS)

    Glusko, Robert J.

    1990-01-01

    Hypertext is a network of information units connected by relational links. A hypertext system is a configuration of hardware and software that presents a hypertext to users and allows them to manage and access the information that it contains. Hypertext is also a user interface concept that closely supports the ways that people use printed information. Hypertext concepts encourage modularity and the elimination of redundancy in data bases because information can be stored only once but viewed in any appropriate context. Hypertext is such a hot idea because it is an enabling technology in that workstations and personal computers finally provide enough local processing power for hypertext user interfaces.

  4. Scientific Issues Addressed by the Kepler Mission

    NASA Technical Reports Server (NTRS)

    Bourcki, W. J.; Koch, D. G.; Lissauer, J. J.; Jenkins, J. M.; DeVincenzi, Donald L. (Technical Monitor)

    1998-01-01

    The Kepler Mission uses a wide field-of-view telescope to photometrically monitor 100,000 main-sequence stars for evidence of planetary transits. Because of the large number of stars monitored and because the mission is designed with a precision (0.002%) sufficient to readily recognize Earth-size planets transiting solar-like stars, several hundred Earth-size planets should be found. Based on the the Dopper velocity observations that find 2% of the main-sequence stars have Jupiter-size planets in short-period orbits, the Kepler mission is also expected to detect about 2000 giant planets. Several questions about the association of planet types and stellar characteristics can be investigated. For example; Are small planets found when Jupiter-mass planets are also present in inner orbits? What is the frequency of small planets compared to Jupiter-mass planets? What is the frequency and distribution of planets intermediate in size and mass to that of Earth and Jupiter? What correlations exist between planet size, distribution, and frequency with the characteristics of the stars they orbit? A comparison between model predictions and observation should be a useful step in evolving better models of planetary system formation and help put the formation of our Solar System in perspective.

  5. ADDRESSING EMERGING ISSUES IN WATER QUALITY ...

    EPA Pesticide Factsheets

    Public concern over cleanliness and safety of source and recreational waters has prompted researchers to look for indicators of water quality. Giving public water authorities multiple tools to measure and monitor levels of chemical contaminants, as well as chemical markers of contamination, simply and rapidly would enhance public protection. The goals of water quality are outlined in the Water Quality Multi-year Plan [http://intranet.epa.gov/ospintra/Planning/wq.pdf] and the research in this task falls under GPRA Goal 2, 2.3.2, Long Term Goals 1, 2, and 4. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and more in-depth coverage of each project. Briefly, each project's objective is stated below.Subtask 1: To integrate state-of-the-art technologies (polar organic chemical integrative samplers, advanced solid-phase extraction methodologies with liquid chromatography/electrospray/mass spectrometry) and apply them to studying the sources and fate of a select list of PPCPs. Application and improvement of analytical methodologies that can detect non-volatile, polar, water-soluble pharmaceuticals in source waters at levels that could be environmentally significant (at concentrations less than parts per billion, ppb). IAG

  6. Team Packs: Addressing Human Sexuality Issues.

    ERIC Educational Resources Information Center

    Florida Univ., Gainesville. Inst. for Child Health Policy.

    This kit provides materials that teach about Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS), sexually transmitted diseases (STDs), and pregnancy using group instructional methodology to actively engage students in the learning process. Using cooperative learning materials and videotape recordings, the program stresses…

  7. Addressing Cyberbullying as a Media Literacy Issue

    ERIC Educational Resources Information Center

    Bhat, Christine Suniti; Chang, Shih-Hua; Linscott, Jamie A.

    2010-01-01

    Background: The Asian region accounts for the highest number of internet and mobile cell phones consumers among the regions of the world. As the use of information and communications technology becomes more and more widespread, the misuse of such technology becomes a concern. Cyberbullying, or bullying using information and communications…

  8. Identification of geostationary satellites using polarization data from unresolved images

    NASA Astrophysics Data System (ADS)

    Speicher, Andy

    In order to protect critical military and commercial space assets, the United States Space Surveillance Network must have the ability to positively identify and characterize all space objects. Unfortunately, positive identification and characterization of space objects is a manual and labor intensive process today since even large telescopes cannot provide resolved images of most space objects. Since resolved images of geosynchronous satellites are not technically feasible with current technology, another method of distinguishing space objects was explored that exploits the polarization signature from unresolved images. The objective of this study was to collect and analyze visible-spectrum polarization data from unresolved images of geosynchronous satellites taken over various solar phase angles. Different collection geometries were used to evaluate the polarization contribution of solar arrays, thermal control materials, antennas, and the satellite bus as the solar phase angle changed. Since materials on space objects age due to the space environment, it was postulated that their polarization signature may change enough to allow discrimination of identical satellites launched at different times. The instrumentation used in this experiment was a United States Air Force Academy (USAFA) Department of Physics system that consists of a 20-inch Ritchey-Chretien telescope and a dual focal plane optical train fed with a polarizing beam splitter. A rigorous calibration of the system was performed that included corrections for pixel bias, dark current, and response. Additionally, the two channel polarimeter was calibrated by experimentally determining the Mueller matrix for the system and relating image intensity at the two cameras to Stokes parameters S0 and S1. After the system calibration, polarization data was collected during three nights on eight geosynchronous satellites built by various manufacturers and launched several years apart. Three pairs of the eight

  9. New French Coverage with Evidence Development for Innovative Medical Devices: Improvements and Unresolved Issues.

    PubMed

    Martelli, Nicolas; van den Brink, Hélène; Borget, Isabelle

    2016-01-01

    We describe here recent modifications to the French Coverage with Evidence Development (CED) scheme for innovative medical devices. CED can be defined as temporary coverage for a novel health product during collection of the additional evidence required to determine whether definitive coverage is possible. The principle refinements to the scheme include a more precise definition of what may be considered an innovative product, the possibility for device manufacturers to request CED either independently or in partnership with hospitals, and the establishment of processing deadlines for health authorities. In the long term, these modifications may increase the number of applications to the CED scheme, which could lead to unsustainable funding for future projects. It will also be necessary to ensure that the study conditions required by national health authorities are suitable for medical devices and that processing deadlines are met for the scheme to be fully operational. Overall, the modifications recently applied to the French CED scheme for innovative medical devices should increase the transparency of the process, and therefore be more appealing to medical device manufacturers.

  10. Unresolved issues in theories of autoimmune disease using myocarditis as a framework.

    PubMed

    Root-Bernstein, Robert; Fairweather, DeLisa

    2015-06-21

    Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dual-affinity T cell receptors. We critically review these theories and relevant mathematical models as they apply to autoimmune myocarditis. All theories share the common assumption that autoimmune diseases are triggered by environmental factors such as infections or chemical exposure. Most, but not all, theories and mathematical models are unifactorial assuming single-agent causation of disease. Experimental and clinical evidence and mathematical models exist to support some aspects of most theories, but evidence/models that support one theory almost invariably supports other theories as well. More importantly, every theory (and every model) lacks the ability to account for some key autoimmune disease phenomena such as the fundamental roles of innate immunity, sex differences in disease susceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical effect of exposure timing and dose on disease induction. We argue that a more comprehensive and integrated theory of autoimmunity associated with new mathematical models is needed and suggest specific experimental and clinical tests for each major theory that might help to clarify how they relate to clinical disease and reveal how theories are related.

  11. The Most Critical Unresolved Issues Associated with Race, Ethnicity, Culture, and Substance Use

    PubMed Central

    Unger, Jennifer B.

    2015-01-01

    This paper discusses the limitations of previous research on race, ethnicity, culture, and substance use. The study offers the following recommendations for future research in this area: (1) move beyond simple comparisons of mutually exclusive groups, (2) focus on the meaning of an ethnic label to the individual, (3) consider the complex interactions between an individual’s cultural identity and the cultural context, (4) understand and acknowledge the researcher’s inherent biases, and (5) translate research findings into practice and policy change. PMID:22217334

  12. [Unresolved issues in the evaluation of research projects involving induced pluripotent stem cells (iPS)].

    PubMed

    Casado, María; de Lecuona, Itziar

    2013-01-01

    This paper identifies problems and analyzes those conflicts posed by the evaluation of research projects involving the collection and use of human induced pluripotent stem cells (iPS) in Spain. Current legislation is causing problems of interpretation, circular and unnecessary referrals, legal uncertainty and undue delays. Actually, this situation may cause a lack of control and monitoring, and even some paralysis in regenerative medicine and cell therapy research, that is a priority nowadays. The analysis of the current legislation and its bioethical implications, led us to conclude that the review of iPS research projects cannot be assimilated to the evaluation of research projects that involve human embryonic stem cell (hESC). In this context, our proposal is based on the review by the Research Ethics Committees and the checkout by the Spanish Comission of Guarantees for Donation and Use of Human Cells and Tissues (CGDUCTH) of human iPS cells research projects. Moreover, this article claims for a more transparent research system, by effectively articulating the Registry on Research Projects. Finally, a model of verification protocol (checklist) for checking out biomedical research projects involving human iPS cells is suggested.

  13. New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy.

    PubMed

    Pike-Overzet, Karin; van der Burg, Mirjam; Wagemaker, Gerard; van Dongen, Jacques J M; Staal, Frank J T

    2007-11-01

    The oncogenic potential of retrovirus-mediated gene therapy has been re-emphasized because four patients developed T-cell acute lymphoblastic leukemia (T-ALL)-like disease from an otherwise successful gene therapy trial for X-linked severe combined immunodeficiency (X-linked SCID). X-linked SCID, a disease caused by inactivating mutations in the IL2Rgamma gene, is part of a heterogeneous group of SCIDs characterized by the lack of T cells in conjunction with the absence of B and/or natural killer (NK) cells. Gene therapy approaches are being developed for this group of diseases. In this review we discuss the various forms of SCID in relation to normal T-cell development. In addition, we consider the possible role of LMO2 and other T-ALL oncogenes in the development of adverse effects as seen in the X-linked SCID gene therapy trial. Furthermore, we debate whether the integration near the LMO2 locus is sufficient to result in T-ALL-like proliferations or whether the gamma-retroviral viral expression of the therapeutic IL2RG gene contributes to leukemogenesis. Finally, we review some newly developed murine models that may have added value for gene therapy safety studies.

  14. Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions.

    PubMed

    Clemente, Maria Grazia; Mandato, Claudia; Poeta, Marco; Vajro, Pietro

    2016-09-28

    Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stress due to genetic/epigenetic background, unfavorable lifestyles, gut microbiota and gut-liver axis dysfunction, and perturbations of trace element homeostasis have been shown to be critical for disease progression and the development of more severe inflammatory and fibrotic stages [non-alcoholic steatohepatitis (NASH)]. Simple clinical and laboratory parameters, such as age, history, anthropometrical data (BMI and waist circumference percentiles), blood pressure, surrogate clinical markers of IR (acanthosis nigricans), abdominal ultrasounds, and serum transaminases, lipids and glucose/insulin profiles, allow a clinician to identify children with obesity and obesity-related conditions, including NAFLD and cardiovascular and metabolic risks. A liver biopsy (the "imperfect" gold standard) is required for a definitive NAFLD/NASH diagnosis, particularly to exclude other treatable conditions or when advanced liver disease is expected on clinical and laboratory grounds and preferably prior to any controlled trial of pharmacological/surgical treatments. However, a biopsy clearly cannot represent a screening procedure. Advancements in diagnostic serum and imaging tools, especially for the non-invasive differentiation between NAFLD and NASH, have shown promising results, e.g., magnetic resonance elastography. Weight loss and physical activity should be the first option of intervention. Effective pharmacological treatments are still under development; however, drugs targeting IR, oxidative stress, proinflammatory pathways, dyslipidemia, gut microbiota and gut liver axis dysfunction are an option for patients who are unable to comply with the recommended lifestyle changes. When morbid obesity prevails, bariatric surgery should be considered.

  15. [Food insecurity among elderly people in 15 districts of the Great Santiago area; an unresolved issue].

    PubMed

    Vargas Puello, Vianny; Alvarado Orellana, Sergio; Atalah Samur, Eduardo

    2013-01-01

    Introducción: Experimentar inseguridad alimentaria determina consecuencias negativas en la nutrición, salud y bienestar general de los adultos mayores y sus familias. En Chile prácticamente no existe información al respecto, a pesar de ser un importante problema de salud pública en otros países de la región. Objetivos: Determinar la prevalencia de inseguridad alimentaria y su relación con factores sociodemográficos, económicos y nutricionales en Adultos Mayores residentes en comunas del nivel socioeconómico medio-bajo y bajo del Gran Santiago. Materiales y métodos: Estudio observacional transversal en 344 adultos mayores de 65 a 74 años; encuesta socioeconómica, demográfica, nutricional y de inseguridad alimentaria en el hogar (HFIAS). Se determinó prevalencia de inseguridad alimentaria y su relación con las variables independientes por modelos de regresión logística multivariados. Resultados: El 40,4% de muestra presentaba inseguridad alimentaria (95% IC 35,2-45,6%), predominantemente de tipo leve, con una proporción mayor en mujeres, en el límite de la significación estadística. La probabilidad de percibir inseguridad alimentaria se asoció significativamente con bajos ingresos familiares (OR 4,2 IC 2,1-8,6), con mayor número de personas en el hogar (OR 2,4), malnutrición por déficit o exceso (OR 2,0), no ser propietario de la vivienda (OR 2,0) y menores ingresos personales (OR 1,8). Conclusiones: Existe una alta prevalencia de inseguridad alimentaria en esta población, la que se asocia con variables sociodemográficas, económicas y nutricionales. La seguridad alimentaria es un importante tema de salud pública y nutrición en el país, que debe ser investigado en mayor profundidad.

  16. Lung disease, antibodies and other unresolved issues in immune globulin therapy for antibody deficiency.

    PubMed

    Cunningham-Rundles, C

    2009-09-01

    Defects of antibody production are the most common of the primary immune defects of man. While these defects have been described in clinical terms for more than five decades, in most cases, the pathogenesis is still poorly understood. The most common clinically important of these is common variable immune deficiency. However there is no strict definition of this defect and the criteria for initiating immune globulin therapy are not standardized, leading to wide variation in treatment practices. In addition there has been no clear means to adequate assess progression of lung disease or elucidate the causes of progressive pulmonary inflammation found in some subjects. Moreover, there are still questions such as what are the best predictors of chronic lung disease and how can we prevent this disorder. Other complications such as autoimmunity, granulomatous disease, gastrointestinal inflation, are similarly poorly understood although treatment with various biological agents has been used with some success. A few bio-markers for assessing clinical and immunologic status have been proposed, and some have proved to be useful, but additional methods to gauge the benefits of therapy, predict outcomes, and harmonize treatment practices are needed. Aside from Ig replacement, additional means of prevention of lung disease may need consideration to reduce lung damage apart from prophylactic antibiotics. These might include using macrolides as anti-inflammatory agents, inhaled corticosteroids, bronchodilators, mucolytics or mechanical or rehabilitative respiratory methods.

  17. Unresolved Issues and New Challenges in Teaching English to Young Learners: The Case of South Korea

    ERIC Educational Resources Information Center

    Garton, Sue

    2014-01-01

    The introduction of languages, especially English, into the primary curriculum around the world has been one of the major language-in-education policy developments in recent years. In countries where English has been compulsory for a number of years, the question arises as to what extent the numerous and well-documented challenges faced by the…

  18. Unresolved Issues Resulting from Changes in DOE’s Synthetic Fuels Commercialization Programs.

    DTIC Science & Technology

    1981-08-17

    production cost savings or greater efficiencies over commercially available technologies . Risk criteria could include scale-up and other technological ...built prior to commercialization of new syntnetic fuel technologies . These plants test out tne technology and economics, and offer an opportunity for...synthetic fuel technologies commercially available. For example, some direct liquefaction technologies are expectea to (i) oe aole to use eastern coal, (2) oe

  19. Widening Access to Scottish Higher Education: Unresolved Issues and Future Challenges

    ERIC Educational Resources Information Center

    Riddell, Sheila

    2016-01-01

    Despite the Scottish Government's frequent affirmation of its commitment to social justice principles, there has of late been a recognition of the need for firmer action to tackle the social class gap in higher education participation, reflecting wider social inequalities in Scotland. In a recent policy statement, Angela Constance, Cabinet…

  20. Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions

    PubMed Central

    Clemente, Maria Grazia; Mandato, Claudia; Poeta, Marco; Vajro, Pietro

    2016-01-01

    Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A “multiple-hit” pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stress due to genetic/epigenetic background, unfavorable lifestyles, gut microbiota and gut-liver axis dysfunction, and perturbations of trace element homeostasis have been shown to be critical for disease progression and the development of more severe inflammatory and fibrotic stages [non-alcoholic steatohepatitis (NASH)]. Simple clinical and laboratory parameters, such as age, history, anthropometrical data (BMI and waist circumference percentiles), blood pressure, surrogate clinical markers of IR (acanthosis nigricans), abdominal ultrasounds, and serum transaminases, lipids and glucose/insulin profiles, allow a clinician to identify children with obesity and obesity-related conditions, including NAFLD and cardiovascular and metabolic risks. A liver biopsy (the “imperfect” gold standard) is required for a definitive NAFLD/NASH diagnosis, particularly to exclude other treatable conditions or when advanced liver disease is expected on clinical and laboratory grounds and preferably prior to any controlled trial of pharmacological/surgical treatments. However, a biopsy clearly cannot represent a screening procedure. Advancements in diagnostic serum and imaging tools, especially for the non-invasive differentiation between NAFLD and NASH, have shown promising results, e.g., magnetic resonance elastography. Weight loss and physical activity should be the first option of intervention. Effective pharmacological treatments are still under development; however, drugs targeting IR, oxidative stress, proinflammatory pathways, dyslipidemia, gut microbiota and gut liver axis dysfunction are an option for patients who are unable to comply with the recommended lifestyle changes. When morbid obesity prevails, bariatric surgery should be considered. PMID:27688650

  1. Dynamic Systems Theory and Management of Children with Cerebral Palsy: Unresolved Issues.

    ERIC Educational Resources Information Center

    Darrah, Johanna; Bartlett, Doreen

    1995-01-01

    This article explains dynamic systems theory (DST), a theoretical framework for the management of children with a diagnosis of cerebral palsy. Three tenets of DST (self-organization of movement, transition, and rate-limiting factors) are examined in light of potential intervention strategies. The need for research to evaluate DST assumptions and…

  2. Unresolved issues in theories of autoimmune disease using myocarditis as a framework

    PubMed Central

    Root-Bernstein, Robert; Fairweather, DeLisa

    2014-01-01

    Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dual-affinity T cell receptors. We critically review these theories and relevant mathematical models as they apply to autoimmune myocarditis. All theories share the common assumption that autoimmune diseases are triggered by environmental factors such as infections or chemical exposure. Most, but not all, theories and mathematical models are unifactorial assuming single-agent causation of disease. Experimental and clinical evidence and mathematical models exist to support some aspects of most theories, but evidence/models that support one theory almost invariably supports other theories as well. More importantly, every theory (and every model) lacks the ability to account for some key autoimmune disease phenomena such as the fundamental roles of innate immunity, sex differences in disease susceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical effect of exposure timing and dose on disease induction. We argue that a more comprehensive and integrated theory of autoimmunity associated with new mathematical models is needed and suggest specific experimental and clinical tests for each major theory that might help to clarify how they relate to clinical disease and reveal how theories are related. PMID:25484004

  3. INTERPRETING THE UNRESOLVED INTENSITY OF COSMOLOGICALLY REDSHIFTED LINE RADIATION

    SciTech Connect

    Switzer, E. R.; Chang, T.-C.; Pen, U.-L.; Voytek, T. C.

    2015-12-10

    Intensity mapping experiments survey the spectrum of diffuse line radiation rather than detect individual objects at high signal-to-noise ratio. Spectral maps of unresolved atomic and molecular line radiation contain three-dimensional information about the density and environments of emitting gas and efficiently probe cosmological volumes out to high redshift. Intensity mapping survey volumes also contain all other sources of radiation at the frequencies of interest. Continuum foregrounds are typically ∼10{sup 2}–10{sup 3} times brighter than the cosmological signal. The instrumental response to bright foregrounds will produce new spectral degrees of freedom that are not known in advance, nor necessarily spectrally smooth. The intrinsic spectra of foregrounds may also not be well known in advance. We describe a general class of quadratic estimators to analyze data from single-dish intensity mapping experiments and determine contaminated spectral modes from the data themselves. The key attribute of foregrounds is not that they are spectrally smooth, but instead that they have fewer bright spectral degrees of freedom than the cosmological signal. Spurious correlations between the signal and foregrounds produce additional bias. Compensation for signal attenuation must estimate and correct this bias. A successful intensity mapping experiment will control instrumental systematics that spread variance into new modes, and it must observe a large enough volume that contaminant modes can be determined independently from the signal on scales of interest.

  4. Interpreting The Unresolved Intensity Of Cosmologically Redshifted Line Radiation

    NASA Technical Reports Server (NTRS)

    Switzer, E. R.; Chang, T.-C.; Masui, K. W.; Pen, U.-L.; Voytek, T. C.

    2016-01-01

    Intensity mapping experiments survey the spectrum of diffuse line radiation rather than detect individual objects at high signal-to-noise ratio. Spectral maps of unresolved atomic and molecular line radiation contain three-dimensional information about the density and environments of emitting gas and efficiently probe cosmological volumes out to high redshift. Intensity mapping survey volumes also contain all other sources of radiation at the frequencies of interest. Continuum foregrounds are typically approximately 10(sup 2)-10(Sup 3) times brighter than the cosmological signal. The instrumental response to bright foregrounds will produce new spectral degrees of freedom that are not known in advance, nor necessarily spectrally smooth. The intrinsic spectra of fore-grounds may also not be well known in advance. We describe a general class of quadratic estimators to analyze data from single-dish intensity mapping experiments and determine contaminated spectral modes from the data themselves. The key attribute of foregrounds is not that they are spectrally smooth, but instead that they have fewer bright spectral degrees of freedom than the cosmological signal. Spurious correlations between the signal and foregrounds produce additional bias. Compensation for signal attenuation must estimate and correct this bias. A successful intensity mapping experiment will control instrumental systematics that spread variance into new modes, and it must observe a large enough volume that contaminant modes can be determined independently from the signal on scales of interest.

  5. Progress Towards an LES Wall Model Including Unresolved Roughness

    NASA Astrophysics Data System (ADS)

    Craft, Kyle; Redman, Andrew; Aikens, Kurt

    2015-11-01

    Wall models used in large eddy simulations (LES) are often based on theories for hydraulically smooth walls. While this is reasonable for many applications, there are also many where the impact of surface roughness is important. A previously developed wall model has been used primarily for jet engine aeroacoustics. However, jet simulations have not accurately captured thick initial shear layers found in some experimental data. This may partly be due to nozzle wall roughness used in the experiments to promote turbulent boundary layers. As a result, the wall model is extended to include the effects of unresolved wall roughness through appropriate alterations to the log-law. The methodology is tested for incompressible flat plate boundary layers with different surface roughness. Correct trends are noted for the impact of surface roughness on the velocity profile. However, velocity deficit profiles and the Reynolds stresses do not collapse as well as expected. Possible reasons for the discrepancies as well as future work will be presented. This work used the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by National Science Foundation grant number ACI-1053575. Computational resources on TACC Stampede were provided under XSEDE allocation ENG150001.

  6. Identifying ethical issues of the Department of the Army civilian and Army Nurse Corps certified registered nurse anesthetists.

    PubMed

    Jenkins, Constance L; Elliott, Aaron R; Harris, Janet R

    2006-08-01

    The purposes of this study were to identify the ethical issues Department of the Army civilian and Army Nurse Corps certified registered nurse anesthetists (CRNAs) encountered in their anesthesia practice and how disturbed they were by these issues. This descriptive study used a secondary data analysis of a cross-sectional survey of Army Nurse Corps officers and Department of the Army civilian registered nurses (N = 5,293). The CRNA subset (n = 97) was obtained from questionnaires that indicated a primary practice setting as anesthesia. The most frequently occurring ethical issue identified was conflict in the nurse-physician relationship, whereas the most disturbing issue was working with incompetent/impaired colleagues. Unresolved ethical conflicts can negatively influence the nurses' morale, leading to avoidance of the issue and contributing to burnout. Identifying the ethical issues and disturbance level experienced by CRNAs should contribute to the development of an ethics education program that addresses issues encountered in CRNA practice.

  7. Emerging Issues.

    ERIC Educational Resources Information Center

    Carter, Denise

    1988-01-01

    Youth services programs and cholesterol in children's diets, two topics that may emerge as issues in schools and school districts in the near future, are addressed. Resources for further information are listed. (CB)

  8. 20 CFR 702.415 - Fees for medical services; unresolved disputes on charges; procedure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Fees for medical services; unresolved... ADMINISTRATION AND PROCEDURE Medical Care and Supervision § 702.415 Fees for medical services; unresolved... seek a hearing pursuant to section 556 of title 5, United States Code. Upon written request for such...

  9. 20 CFR 702.415 - Fees for medical services; unresolved disputes on charges; procedure.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Fees for medical services; unresolved... ADMINISTRATION AND PROCEDURE Medical Care and Supervision § 702.415 Fees for medical services; unresolved... seek a hearing pursuant to section 556 of title 5, United States Code. Upon written request for such...

  10. 20 CFR 702.415 - Fees for medical services; unresolved disputes on charges; procedure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Fees for medical services; unresolved... ADMINISTRATION AND PROCEDURE Medical Care and Supervision § 702.415 Fees for medical services; unresolved... seek a hearing pursuant to section 556 of title 5, United States Code. Upon written request for such...

  11. Bioreactors Addressing Diabetes Mellitus

    PubMed Central

    Minteer, Danielle M.; Gerlach, Jorg C.

    2014-01-01

    The concept of bioreactors in biochemical engineering is a well-established process; however, the idea of applying bioreactor technology to biomedical and tissue engineering issues is relatively novel and has been rapidly accepted as a culture model. Tissue engineers have developed and adapted various types of bioreactors in which to culture many different cell types and therapies addressing several diseases, including diabetes mellitus types 1 and 2. With a rising world of bioreactor development and an ever increasing diagnosis rate of diabetes, this review aims to highlight bioreactor history and emerging bioreactor technologies used for diabetes-related cell culture and therapies. PMID:25160666

  12. Bioreactors addressing diabetes mellitus.

    PubMed

    Minteer, Danielle M; Gerlach, Jorg C; Marra, Kacey G

    2014-11-01

    The concept of bioreactors in biochemical engineering is a well-established process; however, the idea of applying bioreactor technology to biomedical and tissue engineering issues is relatively novel and has been rapidly accepted as a culture model. Tissue engineers have developed and adapted various types of bioreactors in which to culture many different cell types and therapies addressing several diseases, including diabetes mellitus types 1 and 2. With a rising world of bioreactor development and an ever increasing diagnosis rate of diabetes, this review aims to highlight bioreactor history and emerging bioreactor technologies used for diabetes-related cell culture and therapies.

  13. In Situ Airborne Instrumentation: Addressing and Solving Measurement Problems in Ice Clouds

    SciTech Connect

    Baumgardner, Darrel; Kok, Greg; Avallone, L.; Bansemer, A.; Borrmann, S.; Brown, P.; Bundke, U.; Chuang, P. Y.; Cziczo, D.; Field, P.; Gallagher, M.; Gayet, J. -F.; Korolev, A.; Kraemer, M.; McFarquhar, G.; Mertes, S.; Moehler, O.; Lance, S.; Lawson, P.; Petters, M. D.; Pratt, K.; Roberts, G.; Rogers, D.; Stetzer, O.; Stith, J.; Strapp, W.; Twohy, C.; Wendisch, M.

    2012-02-01

    A meeting of 31 international experts on in situ measurements from aircraft was held to identify unresolved questions concerning ice formation and evolution in ice clouds, assess the current state of instrumentation that can address these problems, introduce emerging technology that may overcome current measurement issues and recommend future courses of action that can improve our understanding of ice cloud microphysical processes and their impact on the environment. The meeting proceedings and outcome has been described in detail in a manuscript submitted to the Bulletin of the American Meteorological Society (BAMS) on March 24, 2011. This paper is currently under review. The remainder of this summary, in the following pages, is the text of the BAMS article. A technical note that will be published by the National Center for Atmospheric Research is currently underway and is expected to be published before the end of the year.

  14. In Situ Airborne Instrumentation: Addressing and Solving Measurement Problems in Ice Clouds

    DOE PAGES

    Baumgardner, Darrel; Kok, Greg; Avallone, L.; ...

    2012-02-01

    A meeting of 31 international experts on in situ measurements from aircraft was held to identify unresolved questions concerning ice formation and evolution in ice clouds, assess the current state of instrumentation that can address these problems, introduce emerging technology that may overcome current measurement issues and recommend future courses of action that can improve our understanding of ice cloud microphysical processes and their impact on the environment. The meeting proceedings and outcome has been described in detail in a manuscript submitted to the Bulletin of the American Meteorological Society (BAMS) on March 24, 2011. This paper is currently undermore » review. The remainder of this summary, in the following pages, is the text of the BAMS article. A technical note that will be published by the National Center for Atmospheric Research is currently underway and is expected to be published before the end of the year.« less

  15. Unresolved questions about the most successful known parasite.

    PubMed

    Ajzenberg, Daniel

    2011-02-01

    Every 3 years, the International Congress on Congenital Toxoplasmosis meeting gathers experts with different backgrounds who are involved in congenital toxoplasmosis: gynecologists, pediatricians, ophthalmologists, microbiologists, epidemiologists and research scientists. Most attendees come from the Americas and Europe, where substantial work has been performed to better understand this disease. Two presentations that stressed major current issues in the field of toxoplasmosis are summarized here.

  16. Endoscope Reprocessing: Update on Controversial Issues

    PubMed Central

    Choi, Hyun Ho

    2015-01-01

    Several issues concerning endoscope reprocessing remain unresolved based on currently available data. Thus, further studies are required to confirm standard practices including safe endoscope shelf life, proper frequency of replacement of some accessories including water bottles and connecting tubes, and microbiological surveillance testing of endoscopes after reprocessing. The efficacy and cost-effectiveness of newer technology that allows automated cleaning and disinfection is one such controversial issue. In addition, there are no guidelines on whether delayed reprocessing and extended soaking may harm endoscope integrity or increase the bioburden on the external or internal device surfaces. In this review, we discuss the unresolved and controversial issues regarding endoscope reprocessing. PMID:26473115

  17. Address tracing for parallel machines

    NASA Technical Reports Server (NTRS)

    Stunkel, Craig B.; Janssens, Bob; Fuchs, W. Kent

    1991-01-01

    Recently implemented parallel system address-tracing methods based on several metrics are surveyed. The issues specific to collection of traces for both shared and distributed memory parallel computers are highlighted. Five general categories of address-trace collection methods are examined: hardware-captured, interrupt-based, simulation-based, altered microcode-based, and instrumented program-based traces. The problems unique to shared memory and distributed memory multiprocessors are examined separately.

  18. Addressing Environmental Health Inequalities

    PubMed Central

    Gouveia, Nelson

    2016-01-01

    Environmental health inequalities refer to health hazards disproportionately or unfairly distributed among the most vulnerable social groups, which are generally the most discriminated, poor populations and minorities affected by environmental risks. Although it has been known for a long time that health and disease are socially determined, only recently has this idea been incorporated into the conceptual and practical framework for the formulation of policies and strategies regarding health. In this Special Issue of the International Journal of Environmental Research and Public Health (IJERPH), “Addressing Environmental Health Inequalities—Proceedings from the ISEE Conference 2015”, we incorporate nine papers that were presented at the 27th Conference of the International Society for Environmental Epidemiology (ISEE), held in Sao Paulo, Brazil, in 2015. This small collection of articles provides a brief overview of the different aspects of this topic. Addressing environmental health inequalities is important for the transformation of our reality and for changing the actual development model towards more just, democratic, and sustainable societies driven by another form of relationship between nature, economy, science, and politics. PMID:27618906

  19. More answers to the still unresolved question of nitrate tolerance.

    PubMed

    Münzel, Thomas; Daiber, Andreas; Gori, Tommaso

    2013-09-01

    Organic nitrates are traditionally felt to be a safe adjuvant in the chronic therapy of patients with coronary artery disease. Despite their long use, progress in the understanding of the pharmacology and mechanism of action of these drugs has been achieved only in the last two decades, with the identification of the role of oxidative stress in the pathophysiology of nitrate tolerance, with, the discovery of the ancillary effects of nitrates, and with the demonstration that nitrate therapy has important chronic side effects that might modify patients' prognosis. These advances are however mostly confined to the molecular level or to studies in healthy volunteers, and the true impact of organic nitrates on clinical outcome remains unknown. Complicating this issue, evidence supports the existence of important differences among the different drugs belonging to the group, and there are reasons to believe that the nitrates should not be treated as a homogeneous class. As well, the understanding of the effects of alternative nitric oxide (NO) donors is currently being developed, and future studies will need to test whether the properties of these new medications may compensate and prevent the abnormalities imposed by chronic nitrate therapy. Intermittent therapy with nitroglycerin and isosorbide mononitrate is now established in clinical practice, but they should neither be considered a definitive solution to the problem of nitrate tolerance. Both these strategies are not deprived of complications, and should currently be seen as a compromise rather than a way fully to exploit the benefits of NO donor therapy.

  20. [Keynote address: Climate change

    SciTech Connect

    Forrister, D.

    1994-12-31

    Broadly speaking, the climate issue is moving from talk to action both in the United States and internationally. While few nations have adopted strict controls or stiff new taxes, a number of them are developing action plans that are making clear their intention to ramp up activity between now and the year 2000... and beyond. There are sensible, economically efficient strategies to be undertaken in the near term that offer the possibility, in many countries, to avoid more draconian measures. These strategies are by-and-large the same measures that the National Academy of Sciences recommended in a 1991 report called, Policy Implications of Greenhouse Warming. The author thinks the Academy`s most important policy contribution was how it recommended the nations act in the face of uncertain science and high risks--that cost effective measures are adopted as cheap insurance... just as nations insure against other high risk, low certainty possibilities, like catastrophic health insurance, auto insurance, and fire insurance. This insurance theme is still right. First, the author addresses how the international climate change negotiations are beginning to produce insurance measures. Next, the author will discuss some of the key issues to watch in those negotiations that relate to longer-term insurance. And finally, the author will report on progress in the United States on the climate insurance plan--The President`s Climate Action Plan.

  1. H2S during circulatory shock: Some unresolved questions

    PubMed Central

    McCook, Oscar; Radermacher, Peter; Volani, Chiara; Asfar, Pierre; Ignatius, Anita; Kemmler, Julia; Möller, Peter; Szabó, Csaba; Whiteman, Matthew; Wood, Mark E.; Wang, Rui; Georgieff, Michael; Wachter, Ulrich

    2014-01-01

    Numerous papers have been published on the role of H2S during circulatory shock. Consequently, knowledge about vascular sulfide concentrations may assume major importance, in particular in the context of “acute on chronic disease”, i.e., during circulatory shock in animals with pre-existing chronic disease. This review addresses the questions i) of the “real” sulfide levels during circulatory shock, and, ii) to which extent injury and pre-existing co-morbidity may affect the expression of H2S producing enzymes under these conditions. In the literature there is a huge range on sulfide blood levels during circulatory shock, in part as a result of the different analytical methods used, but also due to the variable of the models and species studied. Clearly, some of the very high levels reported should be questioned in the context of the well-known H2S toxicity. As long as “real” sulfide levels during circulatory shock are unknown and/or undetectable “on line” due to the lack of appropriate techniques, it appears to be premature to correlate the measured blood levels of hydrogen sulfide with the severity of shock or the H2S therapy-related biological outcomes. The available data on the tissue expression of the H2S-releasing enzymes during circulatory shock suggest that a “constitutive” CSE expression may play a crucial role of for the maintenance of organ function, at least in the kidney. The data also indicate that increased CBS and CSE expression, in particular in the lung and the liver, represents an adaptive response to stress states. PMID:24650697

  2. Monte Carlo testing of unresolved resonance treatment for fast and intermediate critical assemblies

    SciTech Connect

    Weinman, J.P.

    1998-10-01

    The purpose of this study is to investigate the eigenvalue sensitivity to changes in unresolved resonance treatment by comparing RACER Monte Carlo calculations for several fast and intermediate spectrum critical experiments. Calculations performed using smooth, dilute-average, tabulated cross sections were compared with calculations using the probability table method to produce stochastically generated resonance cross sections in the unresolved resonance region. The use of the probability table method is superior to the dilute-average cross section method for representing the unresolved resonance region because the table method properly accounts for resonance self shielding; thereby, reducing the effectiveness of the cross sections in the region. The unresolved resonance region is typically found in the intermediate and fast energy range. Eleven benchmark critical assemblies that span a range of {sup 235}U enrichments (93.8 to 10.2%) and four highly enriched {sup 239}Pu and {sup 233}U assemblies were analyzed. These benchmarks were chosen to accentuate the reactivity importance of the unresolved resonance range.

  3. Addressing anniversary reactions of trauma through group process: the Hurricane Katrina anniversary wellness workshops.

    PubMed

    Nemeth, Darlyne G; Kuriansky, Judy; Reeder, Kenneth P; Lewis, Amity; Marceaux, Kristin; Whittington, Taighlor; Olivier, Traci W; May, Natasha E; Safier, Jessica A

    2012-01-01

    Natural disasters such as Hurricane Katrina, which devastated the Gulf Coast of the United States in the summer of 2005, have highlighted the need to develop effective post-trauma psychotherapeutic intervention strategies, not only to deal with the immediate psychological aftermath of trauma, but also the long-term effects of anniversary reactions. Governmental responses to Hurricane Katrina relief were greatly criticized for disorganization and delay. Both immediately afterwards and in ensuing months, people's life needs often were not addressed. People-to-people individual and group grassroots efforts, including those provided by mental health professionals, however, did reach local communities to service immediate needs and long-term emotional reactions. The present paper describes one such effort designed to help survivors cope on the occasion of the first anniversary of Hurricane Katrina. Specifically, anniversary reaction group workshops were held to address unresolved emotional issues and to promote healing by encouraging belonging, comfort, security, and resilience. The ultimate goal of these wellness workshops was to assist participants in understanding and resolving their anniversary reactions. Preliminary quantitative and qualitative findings suggested that this workshop format helped participants face their anniversary reactions, address their related psychological sequelae, and deal with their physical displacement. Participants were then able to find the emotional strength to reattach, form new communities, and begin problem solving. These methods, with appropriate cultural modifications, were subsequently used in China, to assist Chinese mental health professionals prepare for the first anniversary of the Sichuan earthquake.

  4. Issues in Peer Review.

    ERIC Educational Resources Information Center

    Sawamura, Mark H.

    2001-01-01

    Based on concerns raised at a workshop at the Southern California College of Optometry, addresses critical issues in the process of peer review of faculty teaching and possible alternatives to these issues as applied to an optometric institution. (EV)

  5. Characterization of Sound Radiation by Unresolved Scales of Motion in Computational Aeroacoustics

    NASA Technical Reports Server (NTRS)

    Rubinstein, Robert; Zhou, Ye

    1999-01-01

    Evaluation of the sound sources in a high Reynolds number turbulent flow requires time-accurate resolution of an extremely large number of scales of motion. Direct numerical simulations will therefore remain infeasible for the forseeable future: although current large eddy simulation methods can resolve the largest scales of motion accurately the, they must leave some scales of motion unresolved. A priori studies show that acoustic power can be underestimated significantly if the contribution of these unresolved scales is simply neglected. In this paper, the problem of evaluating the sound radiation properties of the unresolved, subgrid-scale motions is approached in the spirit of the simplest subgrid stress models: the unresolved velocity field is treated as isotropic turbulence with statistical descriptors, evaluated from the resolved field. The theory of isotropic turbulence is applied to derive formulas for the total power and the power spectral density of the sound radiated by a filtered velocity field. These quantities are compared with the corresponding quantities for the unfiltered field for a range of filter widths and Reynolds numbers.

  6. 20 CFR 702.414 - Fees for medical services; unresolved disputes on prevailing charges.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... incorrectly identified by medical procedure code; (ii) that the presence of a severe or concomitant medical... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Fees for medical services; unresolved... ADMINISTRATION AND PROCEDURE Medical Care and Supervision § 702.414 Fees for medical services;...

  7. 20 CFR 702.414 - Fees for medical services; unresolved disputes on prevailing charges.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... incorrectly identified by medical procedure code; (ii) that the presence of a severe or concomitant medical... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Fees for medical services; unresolved... ADMINISTRATION AND PROCEDURE Medical Care and Supervision § 702.414 Fees for medical services;...

  8. Unresolved trauma in mothers: Intergenerational effects and the role of reorganization

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A mother's unresolved trauma may interfere with her ability to sensitively respond to her infant, thus affecting the development of attachment in her own child, and potentially contributing to the intergenerational transmission of trauma. One novel construct within the Dynamic Maturational Model of ...

  9. Impact of MCNP unresolved resonance probability-table treatment on uranium and plutonium benchmarks

    SciTech Connect

    Mosteller, R.D.; Little, R.C.

    1998-12-31

    Versions of MCNP up through and including 4B have not accurately modeled neutron self-shielding effects in the unresolved resonance energy region. Recently, a probability-table treatment has been incorporated into a developmental version of MCNP. This paper presents MCNP results for a variety of uranium and plutonium critical benchmarks, calculated with and without the probability-table treatment.

  10. Association between the serotonin transporter promoter polymorphism (5-HTTLPR) and adult unresolved attachment

    PubMed Central

    Caspers, Kristin M; Paradiso, Sergio; Yucuis, Rebecca; Troutman, Beth; Arndt, Stephan; Philibert, Robert

    2013-01-01

    Research on antecedents of organized attachment has focused on the quality of caregiving received during childhood. In recent years, research has begun to examine the influence of genetic factors on quality of infant attachment. However, no published studies report on the association between specific genetic factors and adult attachment. This study examined the link between the 5-HTTLPR promoter polymorphism of the serotonin transporter gene and adult unresolved attachment assessed with the Adult Attachment Interview. Genetic material and information on attachment-related loss or trauma were available for 86 participants. Multivariate regression analyses showed an association between the short 5-HTTLPR allele and increased risk for unresolved attachment. Temperament traits and psychological symptoms did not affect the association between 5-HTTLPR and unresolved attachment. The authors hypothesize that the increased susceptibility to unresolved attachment among carriers of the short allele of 5-HTTLPR is consistent with the role of serotonin in modulation of frontal–amygdala circuitry. The findings challenge current thinking by demonstrating significant genetic influences on a phenomenon previously thought to be largely environmentally driven. PMID:19209991

  11. The Nature of the Unresolved Extragalactic Cosmic Soft X-Ray Background

    NASA Technical Reports Server (NTRS)

    Cappelluti, N.; Ranalli, P.; Roncarelli, M.; Arevalo, P.; Zamorani, G.; Comastri, A.; Gilli, R.; Rovilos, E.; Vignali, C.; Allevato, V.; Finoguenov, A.; Miyaji, T.; Nicastro, F.; Georgantopoulos, I.; Kashlinsky, A.

    2013-01-01

    In this paper we investigate the power spectrum of the unresolved 0.5-2 keV cosmic X-ray background (CXB) with deep Chandra 4-Msec (Ms) observations in the Chandra Deep Field South (CDFS). We measured a signal that, on scales >30 arcsec, is significantly higher than the shot noise and is increasing with angular scale. We interpreted this signal as the joint contribution of clustered undetected sources like active galactic nuclei (AGN), galaxies and the intergalactic medium (IGM). The power of unresolved cosmic source fluctuations accounts for approximately 12 per cent of the 0.5-2 keV extragalactic CXB. Overall, our modelling predicts that approximately 20 per cent of the unresolved CXB flux is produced by low-luminosity AGN, approximately 25 per cent by galaxies and approximately 55 per cent by the IGM. We do not find any direct evidence of the so-called 'warm hot intergalactic medium' (i.e. matter with 10(exp 5) less than T less than 10(exp 7) K and density contrast delta less than 1000), but we estimated that it could produce about 1/7 of the unresolved CXB. We placed an upper limit on the space density of postulated X-ray-emitting early black holes at z greater than 7.5 and compared it with supermassive black hole evolution models.

  12. Association between the serotonin transporter promoter polymorphism (5-HTTLPR) and adult unresolved attachment.

    PubMed

    Caspers, Kristin M; Paradiso, Sergio; Yucuis, Rebecca; Troutman, Beth; Arndt, Stephan; Philibert, Robert

    2009-01-01

    Research on antecedents of organized attachment has focused on the quality of caregiving received during childhood. In recent years, research has begun to examine the influence of genetic factors on quality of infant attachment. However, no published studies report on the association between specific genetic factors and adult attachment. This study examined the link between the 5-HTTLPR promoter polymorphism of the serotonin transporter gene and adult unresolved attachment assessed with the Adult Attachment Interview. Genetic material and information on attachment-related loss or trauma were available for 86 participants. Multivariate regression analyses showed an association between the short 5-HTTLPR allele and increased risk for unresolved attachment. Temperament traits and psychological symptoms did not affect the association between 5-HTTLPR and unresolved attachment. The authors hypothesize that the increased susceptibility to unresolved attachment among carriers of the short allele of 5-HTTLPR is consistent with the role of serotonin in modulation of frontal-amygdala circuitry. The findings challenge current thinking by demonstrating significant genetic influences on a phenomenon previously thought to be largely environmentally driven.

  13. Unresolved Attachment, PTSD, and Dissociation in Women with Childhood Abuse Histories

    ERIC Educational Resources Information Center

    Stovall-McClough, K. Chase; Cloitre, Marylene

    2006-01-01

    The primary objective of this study was to examine unresolved trauma as assessed by the Adult Attachment Interview and current psychiatric symptoms, focusing on posttraumatic stress disorder (PTSD) and dissociation, in a group of adult female childhood abuse survivors. The authors examined psychiatric symptoms and attachment representations in a…

  14. Qualitative and quantitative assessment of Unresolved Complex Mixture in PM2.5 of Bakersfield, CA.

    EPA Science Inventory

    The 2010 CalNex (California Nexus) field experiment offered an opportunity for detailed characterization of atmospheric particulate carbon composition and sources in Bakersfield, CA. In the current study, the authors describe and employ a new protocol for reporting unresolved com...

  15. Issues impacting therapeutic outcomes in pediatric patients: an overview.

    PubMed

    Kalra, Atin; Goindi, Shishu

    2014-01-01

    The quest for achieving optimal therapeutic outcomes in pediatric patients has evaded the healthcare professionals for long and often lack of child specific dosage forms and the associated events that follow with it have been considered to be major contributor towards suboptimal outcomes. Consequently, there have been sustained efforts over the years to address this issue with the enactment of legislations like Best Pharmaceutical for Children Act (BPCA), Pediatric Research Equity Act (PREA) and Pediatric Regulation by European Union (EU) to incentivise the participation of pharmaceutical industry towards development of child friendly dosage forms. Initiatives taken in past by organisations like World Health Organisation (WHO) and Drugs for Neglected Diseases Initiative (DNDi) to spur the development of child friendly dosage forms has helped to address issues pertaining to management of Human Immunodeficiency Virus (HIV) and malaria in pediatric patients. Present efforts aimed at developing child friendly dosage forms include oro-dispersible platforms including thin films and mini-tablets. Despite these leaps and advancements in developing better dosage forms for children, lower therapeutic outcomes in pediatric patients continue to remain an unresolved issue because of detrimental effects of additional factors such as parents understanding of label instructions and complexities involved in executing pediatric clinical studies thus requiring a concerted effort from pharmaceutical companies, academic researchers, parents and healthcare providers to work for better treatment outcomes in children.

  16. Crunch Seen on Ed. Issues after Election

    ERIC Educational Resources Information Center

    Klein, Alyson

    2012-01-01

    From the White House to Capitol Hill, the winners in this week's elections won't have much time to savor their victories. Even as federal policymakers sort out the political landscape, the remainder of 2012 and the early months of 2013 are likely to be dominated by divisive, unresolved issues with broad consequences for K-12 and higher…

  17. Social Security and Undergraduates with Disabilities: An Analysis of the National Postsecondary Student Aid Survey. Addressing Trends in Development in Secondary Education and Transition. Information Brief. Vol. 3, Issue 4.

    ERIC Educational Resources Information Center

    Berry, Hugh; Conway, Megan A.; Change, Kelly B.T.

    2004-01-01

    The purpose of this brief is to describe the characteristics of undergraduate students receiving Social Security Disability Insurance (SSDI) and Social Security Administration (SSI) benefits as they relate to issues of participation in postsecondary education and employment. This brief describes results from the National Postsecondary Student Aid…

  18. Addressing Your Child's Weight at the Doctor

    MedlinePlus

    ... a Healthy Heart Healthy Kids Our Kids Programs Childhood Obesity What is childhood obesity? Overweight in Children BMI in Children Is Childhood Obesity an Issue in Your Home? Addressing your Child's ...

  19. The solar extreme ultra-violet corona: Resolved loops and the unresolved active region corona

    NASA Astrophysics Data System (ADS)

    Cirtain, Jonathan Wesley

    In this work, physical characteristics of the solar corona as observed in the Extreme Ultra-Violet (EUV) regime are investigated. The focus will be the regions of intense EUV radiation generally found near the locations of sunspots. These regions are commonly called active regions. Multiple space- based observing platforms have been deployed in the last decade; it is possible to use several of these observatories in combination to develop a more complete picture of the solar corona. Joint Observing Program 146 was created to collect spectroscopic intensities using the Coronal Diagnostic Spectrometer on Solar and Heliospheric Observatory and EUV images using NASA's Transition Region and Coronal Explorer. The emission line intensities are analyzed to develop an understanding of the temperature and density of the active region coronal plasma. However, the performance of the CDS instrument in the spatial and temporal domains is limited and to compensate for these limitations, data collected by the TRACE instrument provide a high spatial and temporal resolution set of observations. One of the most exciting unsolved problems in solar astrophysics is to understand why the corona maintains a temperature roughly two orders of magnitude higher than the underlying material. A detailed investigation of the coronal emission has provided constraints on models of the heating mechanism, since the temperature, density and evolution of emission rates for multiple ionic species are indicative of the mechanism(s) working to heat the corona. The corona appears to consist of multiple unresolved structures as well as resolved active region structures, called coronal loops. The purpose of the present work is to determine the characteristics of the unresolved background corona. Using the characterizations of the coronal unresolved background, results for loops after background subtraction are also presented. This work demonstrates the magnitude of the unresolved coronal emission with

  20. Distinguishing dark matter from unresolved point sources in the Inner Galaxy with photon statistics

    SciTech Connect

    Lee, Samuel K.; Lisanti, Mariangela; Safdi, Benjamin R. E-mail: mlisanti@princeton.edu

    2015-05-01

    Data from the Fermi Large Area Telescope suggests that there is an extended excess of GeV gamma-ray photons in the Inner Galaxy. Identifying potential astrophysical sources that contribute to this excess is an important step in verifying whether the signal originates from annihilating dark matter. In this paper, we focus on the potential contribution of unresolved point sources, such as millisecond pulsars (MSPs). We propose that the statistics of the photons—in particular, the flux probability density function (PDF) of the photon counts below the point-source detection threshold—can potentially distinguish between the dark-matter and point-source interpretations. We calculate the flux PDF via the method of generating functions for these two models of the excess. Working in the framework of Bayesian model comparison, we then demonstrate that the flux PDF can potentially provide evidence for an unresolved MSP-like point-source population.

  1. [Attachment and somatoform disorders: low coherence and unresolved states of mind related to chronic pain].

    PubMed

    Neumann, Eva; Nowacki, Katja; Roland, Inga Christin; Kruse, Johannes

    2011-06-01

    Although attachment theory has become an influential approach used for the study of mental disorders, hitherto little has been known about the relation of attachment to somatoform disorders. In this study 15 patients with a somatoform pain disorder were compared with 15 non-clinical control participants. Attachment representations were measured by the Adult Attachment Interview (AAI). Compared to the control group, the patient group describes parental behavior as less loving and more rejecting, expresses more anger towards the mother, shows more signs of unresolved loss and trauma, and their interviews are markedly less coherent. None of the patients is classified as secure; the majority falls within the unresolved category. The findings of this study can contribute to a better understanding of the often described adversities in the therapeutic alliance with these patients.

  2. Report on the Workshop Resolved and Unresolved Stellar PopUlaTIoNs (RASPUTIN)

    NASA Astrophysics Data System (ADS)

    Bono, G.; Valenti, E.

    2014-12-01

    The workshop aimed at sharing and discussing observations and diagnostics, together with models and simulations, of the resolved and unresolved stellar populations in galaxies from the Milky Way to the distant Universe. Special attention was paid to recent results concerning galaxy formation and evolution, fostering the exchange of ideas and techniques in dealing with nearby stellar populations. There will be no published proceedings, but presentations are available for download from the workshop web page (www.eso.org/sci/meetings/2014/rasputin2014).

  3. Accounting for the Unresolved X-ray Background with Sterile Neutrino Dark Matter

    SciTech Connect

    Cumberbatch, D.T.; Silk, Joseph

    2007-11-20

    We consider a scenario where keV sterile neutrinos constitute all of the currently inferred dark matter abundance, whose radiative decays could potentially account for the flux contributions to the X-ray background (XRB) by unresolved sources. Here we apply integrated flux methods to results from the observations of the North/South Chandra deep fields (CDF-N/S) in order to deduce constraints on the sterile neutrino mass-mixing parameters.

  4. Determining Satellite Rotation Rates for Unresolved Targets Using Temporal Variations in Spectral Signatures

    NASA Astrophysics Data System (ADS)

    Coughlin, J.

    2014-09-01

    Analyzing temporal variations in spectral signatures is a potential tool to determine the rotation rates, spin axes, and attitude of satellites from unresolved spectral images. By calculating rotational information, analysts can define the satellite in terms of its space object taxonomy1. This research presents an evaluation into different temporal pattern matching techniques to determine the rotation rates of simulated satellites. This investigation uses detailed models to simulate satellite signatures in the visible and near infrared as seen by a hypothetical ground sensor. At each time step, spectral and photometric images are averaged to yield unresolved images as the satellite is propagated through the field-of-view. For each image, a material pattern map is generated based on either material identification or spectral similarity. Using techniques similar to those used to determine the rotations of asteroids from fragmented light curves, we determine satellite rotation rate and spin axes. For unresolved targets, this approach uses the periodic changes in the irradiance but evaluates the additional information available from the spectra. Previous work (Coughlin, AMOS 2009) has shown the utility of spectral material mapping for satellite anomaly detection. This research continues that effort by investigating satellite rotation and attitude information. 1Towards an Artificial Space Object Taxonomy, Wilkins, Pfeffer, Schumacher, Jah

  5. DRD4 genotype moderates the impact of parental problems on unresolved loss or trauma.

    PubMed

    Bakermans-Kranenburg, Marian J; van IJzendoorn, Marinus H; Caspers, Kristin; Philibert, Robert

    2011-05-01

    In the current study we tested whether the dopamine receptor D4 (DRD4) genotype moderates the association of experienced parental problems during childhood (e.g., parental depression, marital discord) with unresolved loss or trauma during the Adult Attachment Interview. To test the specificity of this moderation the role of the serotonin transporter gene promoter (5-HTTLPR) was also examined. Subjects were 124 adopted adults (mean age 39 years). Participants with the DRD4-7 repeat (7R) allele who experienced parental problems had the highest scores for unresolved loss or trauma whereas participants with DRD4-7R who did not experience parental problems showed the lowest ratings. Among participants without DRD4-7R, the parental problems during childhood did not make a difference. 5-HTTLPR did not moderate the relation between parental problems and unresolved loss or trauma. Our study shows heightened susceptibility to environmental influences for carriers of the DRD4-7R allele, and suggests that the interplay between specific dopamine-related genes and family contexts leads to more or less successful coping with adverse childhood experiences.

  6. Search for unresolved sources in the COBE-DMR two-year sky maps

    NASA Technical Reports Server (NTRS)

    Kogut, A.; Banday, A. J.; Bennett, C. L.; Hinshaw, G.; Loewenstein, K.; Lubin, P.; Smoot, G. F.; Wright, E. L.

    1994-01-01

    We have searched the temperature maps from the Cosmic Background Explorer (COBE) Differential Microwave Radiometers (DMR) first two years of data for evidence of unresolved sources. The high-latitude sky (absolute value of b greater than 30 deg) contains no sources brighter than 192 microKelvin thermodynamic temperature (322 Jy at 53 GHz). The cumulative count of sources brighter than threshold T, N(greater than T), is consistent with a superposition of instrument noise plus scale-invariant spectrum of cosmic temperature fluctuations normalized to Q(sub rms-PS) = 17 microKelvin. We examine the temperature maps toward nearby clusters and find no evidence for any Sunyaev-Zel'dovich effect, delta y less than 7.3 x 10(exp -6) (95% CL) averaged over the DMR beam. We examine the temperature maps near the brightest expected radio sources and detect no evidence of significant emission. The lack of bright unresolved sources in the DMR maps, taken with anisotropy measurements on smaller angular scales, places a weak constraint on the integral number density of any unresolved Planck-spectrum sources brighter than flux density S, n(greater than S) less than 2 x 10(exp 4)/(S/1 Jy)(exp 2)/sr.

  7. Search for unresolved sources in the COBE-DMR two-year sky maps

    NASA Astrophysics Data System (ADS)

    Kogut, A.; Banday, A. J.; Bennett, C. L.; Hinshaw, G.; Loewenstein, K.; Lubin, P.; Smoot, G. F.; Wright, E. L.

    1994-10-01

    We have searched the temperature maps from the Cosmic Background Explorer (COBE) Differential Microwave Radiometers (DMR) first two years of data for evidence of unresolved sources. The high-latitude sky (absolute value of b greater than 30 deg) contains no sources brighter than 192 microKelvin thermodynamic temperature (322 Jy at 53 GHz). The cumulative count of sources brighter than threshold T, N(greater than T), is consistent with a superposition of instrument noise plus scale-invariant spectrum of cosmic temperature fluctuations normalized to Qrms-PS = 17 microKelvin. We examine the temperature maps toward nearby clusters and find no evidence for any Sunyaev-Zel'dovich effect, delta y less than 7.3 x 10-6 (95% CL) averaged over the DMR beam. We examine the temperature maps near the brightest expected radio sources and detect no evidence of significant emission. The lack of bright unresolved sources in the DMR maps, taken with anisotropy measurements on smaller angular scales, places a weak constraint on the integral number density of any unresolved Planck-spectrum sources brighter than flux density S, n(greater than S) less than 2 x 104/(S/1 Jy)2/sr.

  8. Lobby Day Issue Briefs.

    ERIC Educational Resources Information Center

    National Council of La Raza, Washington, DC. Office of Research Advocacy and Legislation.

    This compilation of seven briefs is intended to help citizens lobby United States senators, representatives, and their staff members on issues of importance to the Hispanic American community. Each brief synopsizes an issue, reviews current proposals for addressing the issue, and suggests the appropriate action that the member of congress should…

  9. A pathogenetic approach to autoimmune skin disease therapy: psoriasis and biological drugs, unresolved issues, and future directions.

    PubMed

    Ayroldi, Emira; Bastianelli, Alessandra; Cannarile, Lorenza; Petrillo, Maria Grazia; Delfino, Domenico V; Fierabracci, Alessandra

    2011-01-01

    Psoriasis is a chronic inflammatory disease with a complex pathophysiology and a multigenic background. Autoimmunity and genetic hallmarks couple to confer the disease, which is characterized by chronic plaques (85-90% of all cases) and/or psoriasis arthritis (PsA), and involve the peripheral and sacro-iliac joints, nails, and skeleton. Dissecting the ethiopathogenetic mechanisms of psoriasis and PsA is a major basic research challenge. One important question is whether a single inflammatory mediator can be responsible for the interactive network that forms between immune cells and cytokines in this disease. Despite much progress, no research has yet been able to define a single model to explain the multifaceted pathogenesis of psoriasis and PsA. It is known that both the innate and adaptive immune systems are involved, antigen presenting cells and T lymphocytes play a prominent role, and that the deregulation of the T helper (Th)- 1/Th-2/Th-17/Th-23 axis is directly implicated in disease pathogenesis. Pharmacological therapy for psoriasis has evolved with the development of human knowledge of the disease pathophysiology. Thus, the first "ethiopathogenetic" drugs (e.g., methotrexate, cyclosporin, and alefacept) inhibited T-cell activation directly or targeted co-accessory molecules implicated in T-cell activation. When the mechanism underlying psoriatic inflammation was accepted as a cytokine network disorder, more specific biologics were studied in murine models and were later used clinically. Tumor necrosis factor was the first successful target of cytokine inhibition therapy for psoriasis and PsA (e.g., infliximab, adalimumab, and etanercept). With the recently discovered role for Th-17 in autoimmunity, drugs targeting interleukin-23 (ustekinumab) have become accepted for the pharmacological treatment of psoriasis. The expansion of pharmacological treatment options for psoriasis is not complete. As the knowledge of pathogenetic mechanisms increases, it may be possible to design therapeutic approaches that selectively target the ethiopathogenetic cells or cytokines while sparing the others. In this way, using a more targeted drug therapy may preserve the integrity of the immune system. Thus, one great struggle in treating this complex disease is the challenge to synthesize the "perfect" drug.

  10. Recent advances, and unresolved issues, in the application of computational modelling to the prediction of the biological effects of nanomaterials.

    PubMed

    Winkler, David A

    2016-05-15

    Nanomaterials research is one of the fastest growing contemporary research areas. The unprecedented properties of these materials have meant that they are being incorporated into products very quickly. Regulatory agencies are concerned they cannot assess the potential hazards of these materials adequately, as data on the biological properties of nanomaterials are still relatively limited and expensive to acquire. Computational modelling methods have much to offer in helping understand the mechanisms by which toxicity may occur, and in predicting the likelihood of adverse biological impacts of materials not yet tested experimentally. This paper reviews the progress these methods, particularly those QSAR-based, have made in understanding and predicting potentially adverse biological effects of nanomaterials, and also the limitations and pitfalls of these methods.

  11. The Effectiveness of Instructor Personalized and Formative Feedback Provided by Instructor in an Online Setting: Some Unresolved Issues

    ERIC Educational Resources Information Center

    Planar, Dolors; Moya, Soledad

    2016-01-01

    Formative feedback has great potential for teaching and learning in online undergraduate programmes. There is a large number of courses where the main source of feedback is provided by the instructor. This is particularly seen in subjects where assessments are designed based on specific activities which are the same for all students, and where the…

  12. Comments on a paper tilted `The sea transport of vitrified high-level radioactive wastes: Unresolved safety issues`

    SciTech Connect

    Sprung, J.L.; McConnell, P.E.; Nigrey, P.J.; Ammerman, D.J.

    1997-05-01

    The cited paper estimates the consequences that might occur should a purpose-built ship transporting Vitrified High Level Waste (VHLW) be involved in a severe collision that causes the VHLW canisters in one Type-B package to spill onto the floor of a major ocean fishing region. Release of radioactivity from VHLW glass logs, failure of elastomer cask seals, failure of VHLW canisters due to stress corrosion cracking (SCC), and the probabilities of the hypothesized accident scenario, of catastrophic cask failure, and of cask recovery from the sea are all discussed.

  13. Mediating equity in shared water between community and industry: The effects of an after school program that addresses adolescents' knowledge, attitudes, and perceptions of water science and environmental issues

    NASA Astrophysics Data System (ADS)

    Patton, Mary Chandler

    This critical ethnography deconstructs how one participant researcher came to understand young adults' changing knowledge about water science and environmental issues in an after school program in Colombia. The program intended to empower self-identified young community leaders by teaching participants to engage community members in discourse related to how environmental factors impact one's level of health and quality of life. The data presented in this study illustrate how student participants responded to long-term teacher engagement and to particular curricular components that included hands-on science teaching and social justice coaching. I assessed how student interest in and knowledge of local water ecology and sanitation infrastructure changed throughout the program. Students' responses to the use of technology and digital media were also included in the analysis. The data demonstrates a dramatic change in student's attitudes and perceptions related to their environment and how they feel about their ability to make positive changes in their community.

  14. Contemporary Native American Address.

    ERIC Educational Resources Information Center

    Maestas, John R., Ed.

    A compilation of 58 representative speeches from the American Indian Community, this book is divided into 2 parts; Part I deals with issues of contemporary concern and Part II illustrates speech types and styles. All speeches are classified by issue as follows: sovereignty (2 speeches, 1 on the rise and fall of Indian sovereignty); trust…

  15. Addressing Ozone Layer Depletion

    EPA Pesticide Factsheets

    Access information on EPA's efforts to address ozone layer depletion through regulations, collaborations with stakeholders, international treaties, partnerships with the private sector, and enforcement actions under Title VI of the Clean Air Act.

  16. A CATALOG OF NEAR-IR SOURCES FOUND TO BE UNRESOLVED WITH MILLIARCSECOND RESOLUTION

    SciTech Connect

    Richichi, A.; Fors, O.; Cusano, F.; Moerchen, M.

    2012-12-15

    Calibration is one of the long-standing problems in optical interferometric measurements, particularly with long baselines which demand stars with angular sizes on the milliarcsecond scale and no detectable companions. While systems of calibrators have been generally established for the near-infrared in the bright source regime (K {approx}< 3 mag), modern large interferometers are sensitive to significantly fainter magnitudes. We aim to provide a list of sources found to be unresolved from direct observations with high angular resolution and dynamic range, which can be used to choose interferometric calibrators. To this purpose, we have used a large number of lunar occultations recorded with the ISAAC instrument at the Very Large Telescope to select sources found to be unresolved and without close companions. An algorithm has been used to determine the limiting angular resolution achieved for each source, taking into account a noise model built from occulted and unocculted portions of the light curves. We have obtained upper limits on the angular sizes of 556 sources, with magnitudes ranging from K{sub s} Almost-Equal-To 4 to 10, with a median of 7.2 mag. The upper limits on possible undetected companions (within Almost-Equal-To 0.''5) range from K{sub s} Almost-Equal-To 8 to 13, with a median of 11.5 mag. One-third of the sources have angular sizes {<=}1 mas, and two-thirds have sizes {<=}2 mas. This list of unresolved sources matches well the capabilities of current large interferometric facilities. We also provide available cross-identifications, magnitudes, spectral types, and other auxiliary information. A fraction of the sources are found to be potentially variable. The list covers parts of the Galactic Bulge and in particular the vicinity of the Galactic Center, where extinction is very significant and traditional lists of calibrators are often insufficient.

  17. "Unresolved Complex Mixture" (UCM): A brief history of the term and moving beyond it.

    PubMed

    Farrington, John W; Quinn, James G

    2015-07-15

    The term "Unresolved Complex Mixture" (UCM) has been used extensively for decades to describe a gas chromatographic characteristic indicative of the presence of fossil fuel hydrocarbons (mainly petroleum hydrocarbons) in hydrocarbons isolated from aquatic samples. We chronicle the origin of the term. While it is still a useful characteristic for screening samples, more modern higher resolution two dimensional gas chromatography and gas chromatography coupled with advanced mass spectrometry techniques (Time-of-Flight or Fourier Transform-Ion Cyclotron Resonance) should be employed for analyses of petroleum contaminated samples. This will facilitate advances in understanding of the origins, fates and effects of petroleum compounds in aquatic environments.

  18. Transition wavelengths and unresolved transition array statistics of ions with Z = 72-89

    NASA Astrophysics Data System (ADS)

    Kilbane, D.

    2011-08-01

    Potential extreme ultraviolet and soft x-ray radiation sources have been identified, using the flexible atomic code (FAC), as emission peaks arising from the 4d-4f and 4p-4d transitions in Pd-like to Rb-like ions of hafnium through actinium. The effects of configuration interaction are investigated and for increasing nuclear charge, these strong emitters are seen to separate and move to shorter wavelengths. Each source is characterized using the unresolved transition array model. They are proposed to complement the currently used nitrogen and argon sources in the 'water window', and as possible successors to tin in next-generation lithography.

  19. Space Station Software Issues

    NASA Technical Reports Server (NTRS)

    Voigt, S. (Editor); Beskenis, S. (Editor)

    1985-01-01

    Issues in the development of software for the Space Station are discussed. Software acquisition and management, software development environment, standards, information system support for software developers, and a future software advisory board are addressed.

  20. The relation of dissociation and mind wandering to unresolved/disorganized attachment: an experience sampling study.

    PubMed

    Marcusson-Clavertz, David; Gušić, Sabina; Bengtsson, Hans; Jacobsen, Heidi; Cardeña, Etzel

    2017-04-01

    Individuals with unresolved/disorganized representations of childhood trauma (U/d attachment) report more psychological distress than others, but little is known about their everyday mentation. In the present study adults with childhood trauma (N = 45) completed the Berkeley-Leiden Adult Attachment Questionnaire-Unresolved (BLAAQ-U) and the Adult Attachment Interview (AAI), and reported everyday mentation during 5 days of experience sampling. The BLAAQ-U and the AAI showed a medium association with each other, but only the former significantly predicted negative affect, dissociation, and low control/awareness of mentation. Contrary to our predictions, U/d attachment did not significantly predict mind wandering, but the BLAAQ-U predicted endorsements of a negative mind wandering style. U/d attachment, as assessed by both instruments, was associated with the Poor attentional control style and beliefs in anomalous mental phenomena. Experience sampling is a valuable way to investigate everyday experiences in individuals with U/d attachment.

  1. A method for selecting M dwarfs with an increased likelihood of unresolved ultracool companionship

    NASA Astrophysics Data System (ADS)

    Cook, N. J.; Pinfield, D. J.; Marocco, F.; Burningham, B.; Jones, H. R. A.; Frith, J.; Zhong, J.; Luo, A. L.; Qi, Z. X.; Lucas, P. W.; Gromadzki, M.; Day-Jones, A. C.; Kurtev, R. G.; Guo, Y. X.; Wang, Y. F.; Bai, Y.; Yi, Z. P.; Smart, R. L.

    2016-04-01

    Locating ultracool companions to M dwarfs is important for constraining low-mass formation models, the measurement of substellar dynamical masses and radii, and for testing ultracool evolutionary models. We present an optimized method for identifying M dwarfs which may have unresolved ultracool companions. We construct a catalogue of 440 694 M dwarf candidates, from Wide-Field Infrared Survey Explorer, Two Micron All-Sky Survey and Sloan Digital Sky Survey, based on optical- and near-infrared colours and reduced proper motion. With strict reddening, photometric and quality constraints we isolate a subsample of 36 898 M dwarfs and search for possible mid-infrared M dwarf + ultracool dwarf candidates by comparing M dwarfs which have similar optical/near-infrared colours (chosen for their sensitivity to effective temperature and metallicity). We present 1082 M dwarf + ultracool dwarf candidates for follow-up. Using simulated ultracool dwarf companions to M dwarfs, we estimate that the occurrence of unresolved ultracool companions amongst our M dwarf + ultracool dwarf candidates should be at least four times the average for our full M dwarf catalogue. We discuss possible contamination and bias and predict yields of candidates based on our simulations.

  2. Lower Oxytocin Plasma Levels in Borderline Patients with Unresolved Attachment Representations.

    PubMed

    Jobst, Andrea; Padberg, Frank; Mauer, Maria-Christine; Daltrozzo, Tanja; Bauriedl-Schmidt, Christine; Sabass, Lena; Sarubin, Nina; Falkai, Peter; Renneberg, Babette; Zill, Peter; Gander, Manuela; Buchheim, Anna

    2016-01-01

    Interpersonal problems and affective dysregulation are core characteristics of borderline personality disorder (BPD). BPD patients predominantly show unresolved attachment representations. The oxytocin (OT) system is associated with human social attachment and affiliative behavior, and OT dysregulation may be related to distinct attachment characteristics. Here, we investigated whether attachment representations are related to peripheral OT levels in BPD patients. Twenty-one female BPD patients and 20 age-, gender-, and education-matched healthy controls (HCs) were assessed with clinical scales and measures of interpersonal and attachment-related characteristics, including the Adult Attachment Projective Picture System (AAP). Plasma OT concentrations were measured prior to and during social exclusion in a virtual ball tossing game (Cyberball). The majority of BPD patients (63.2%) but no HCs showed unresolved (disorganized) attachment representations. In this subgroup of patients, baseline OT plasma levels were significantly lower than in BPD patients with organized attachment representations. This pilot study extends previous findings of altered OT regulation in BPD as a putative key mechanism underlying interpersonal dysregulation. Our results provide first evidence that altered OT plasma levels are related to disorganized attachment representations in BPD patients.

  3. Lower Oxytocin Plasma Levels in Borderline Patients with Unresolved Attachment Representations

    PubMed Central

    Jobst, Andrea; Padberg, Frank; Mauer, Maria-Christine; Daltrozzo, Tanja; Bauriedl-Schmidt, Christine; Sabass, Lena; Sarubin, Nina; Falkai, Peter; Renneberg, Babette; Zill, Peter; Gander, Manuela; Buchheim, Anna

    2016-01-01

    Interpersonal problems and affective dysregulation are core characteristics of borderline personality disorder (BPD). BPD patients predominantly show unresolved attachment representations. The oxytocin (OT) system is associated with human social attachment and affiliative behavior, and OT dysregulation may be related to distinct attachment characteristics. Here, we investigated whether attachment representations are related to peripheral OT levels in BPD patients. Twenty-one female BPD patients and 20 age-, gender-, and education-matched healthy controls (HCs) were assessed with clinical scales and measures of interpersonal and attachment-related characteristics, including the Adult Attachment Projective Picture System (AAP). Plasma OT concentrations were measured prior to and during social exclusion in a virtual ball tossing game (Cyberball). The majority of BPD patients (63.2%) but no HCs showed unresolved (disorganized) attachment representations. In this subgroup of patients, baseline OT plasma levels were significantly lower than in BPD patients with organized attachment representations. This pilot study extends previous findings of altered OT regulation in BPD as a putative key mechanism underlying interpersonal dysregulation. Our results provide first evidence that altered OT plasma levels are related to disorganized attachment representations in BPD patients. PMID:27064696

  4. A critical evaluation of semianalytic methods in the study of centrally heated, unresolved, infrared sources

    NASA Technical Reports Server (NTRS)

    Doty, Steven D.; Leung, Chun Ming

    1994-01-01

    We critically evaluate current methods of analysis in infrared (IR) astronomy and investigate the conditions under which these semianalytic methods are reliable. Specifically we examine the usual assumptions of homogeneities in dust density and temperature, and neglect of opacity effects when applied to internally heated, unresolved IR sources. To accomplish this, a series of radiation transport models for these sources have been constructed. The model results are treated as observed quantities and analyzed to derive the source parameters, using simple semianalytic methods. The discrepancies between the derived and actual model parameters can then be attributed to the limitations of the analysis methods and provide a measure of their reliability. Applying this approach to centrally heated, unresolved IR sources, we have studied in detail the following diagnostic problems: (1) determination of dust mass from monochromatic and integrated luminosities; (2) estimation of dust temperature distribution from color temperatures derived from the flux spectrum; and (3) determination of the empirical grain emissivity law (opacity function) for both continuum and spectral features.

  5. The Impact of Unresolved Turbulence on the Escape Fraction of Lyman Continuum Photons

    NASA Astrophysics Data System (ADS)

    Safarzadeh, M.; Scannapieco, E.

    2016-11-01

    We investigate the relation between the turbulent Mach number ({ M }) and the escape fraction of Lyman continuum photons ({f}{esc}) in high-redshift galaxies. Approximating the turbulence as isothermal and isotropic, we show that the increase in the variance in column densities from { M }=1 to { M }=10 causes {f}{esc} to increase by ≈ 25%, and the increase from { M }=1 to { M }=20 causes {f}{esc} to increases by ≈ 50% for a medium with opacity τ ≈ 1. At a fixed Mach number, the correction factor for escape fraction relative to a constant column density case scales exponentially with the opacity in the cell, which has a large impact for simulated star-forming regions. Furthermore, in simulations of isotropic turbulence with full atomic/ionic cooling and chemistry, the fraction of HI drops by a factor of ≈ 2.5 at { M }≈ 10 even when the mean temperature is ≈ 5× {10}3 {{K}}. If turbulence is unresolved, these effects together enhance {f}{esc} by a factor \\gt 3 at Mach numbers above 10. Such Mach numbers are common at high redshifts where vigorous turbulence is driven by supernovae, gravitational instabilities, and merger activity, as shown both by numerical simulations and observations. These results, if implemented in the current hydrodynamical cosmological simulations to account for unresolved turbulence, can boost the theoretical predictions of the Lyman Continuum photon escape fraction and further constrain the sources of reionization.

  6. Invitational Addresses, 1965.

    ERIC Educational Resources Information Center

    Gates, Arthur I.; And Others

    The full texts of invitational addresses given at the 1965 International Reading Association (IRA) Convention in Detroit, Michigan, by six recipients of IRA citation awards are presented. Gates suggests steps IRA should take to revive and redirect reading research. McCallister discusses the implications of the changing and expanding vocabulary of…

  7. States Address Achievement Gaps.

    ERIC Educational Resources Information Center

    Christie, Kathy

    2002-01-01

    Summarizes 2 state initiatives to address the achievement gap: North Carolina's report by the Advisory Commission on Raising Achievement and Closing Gaps, containing an 11-point strategy, and Kentucky's legislation putting in place 10 specific processes. The North Carolina report is available at www.dpi.state.nc.us.closingthegap; Kentucky's…

  8. Addressing Sexual Harassment

    ERIC Educational Resources Information Center

    Young, Ellie L.; Ashbaker, Betty Y.

    2008-01-01

    This article discusses ways on how to address the problem of sexual harassment in schools. Sexual harassment--simply defined as any unwanted and unwelcome sexual behavior--is a sensitive topic. Merely providing students, parents, and staff members with information about the school's sexual harassment policy is insufficient; schools must take…

  9. Diagnostic Issues and Controversies in DSM-5: Return of the False Positives Problem.

    PubMed

    Wakefield, Jerome C

    2016-01-01

    The fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was the most controversial in the manual's history. This review selectively surveys some of the most important changes in DSM-5, including structural/organizational changes, modifications of diagnostic criteria, and newly introduced categories. It analyzes why these changes led to such heated controversies, which included objections to the revision's process, its goals, and the content of altered criteria and new categories. The central focus is on disputes concerning the false positives problem of setting a valid boundary between disorder and normal variation. Finally, this review highlights key problems and issues that currently remain unresolved and need to be addressed in the future, including systematically identifying false positive weaknesses in criteria, distinguishing risk from disorder, including context in diagnostic criteria, clarifying how to handle fuzzy boundaries, and improving the guidelines for "other specified" diagnosis.

  10. Unresolved loss, a risk factor for offspring, predicts event-related potential responses to death-related imagery.

    PubMed

    Bahm, Naomi I Gribneau; Simon-Thomas, Emiliana R; Main, Mary; Hesse, Erik

    2017-01-01

    This study investigates whether individual differences in attachment status can be detected by electrophysiological responses to loss-themed pictures. The Adult Attachment Interview (AAI) was used to identify discourse/reasoning lapses during the discussion of loss experiences via death that place speakers in the Unresolved/disorganized AAI category. In parents, Unresolved AAI status has been associated with Disorganized infant Strange Situation response, a known risk factor for psychopathology (e.g., internalizing/externalizing/dissociation). This association has been related to anomalous frightening (FR) parental behavior in the infant's presence, behavior presumed to be instigated by vulnerability to trauma-related fright. Here, psychophysiological methods were utilized to examine whether Unresolved AAI status could be detected in brain responses to subtle/symbolic reminders of loss. One year after AAI administration, 31 undergraduate women who had experienced loss (16 Unresolved) underwent continuous electroencephalogram (EEG) recording during a picture-viewing, valence-rating task. Picture onset-locked event-related potentials (ERPs) revealed millisecond responses to 4 picture categories: pleasant people, pleasant nature, cemetery (symbolic death), and gruesome death (dead or dying people). Participants' valence ratings did not differ between groups across picture categories. However, the N2 ERP, implicated in detecting stimulus salience, was selectively greater in Unresolved participants viewing cemetery scenes; it was in fact as high as the N2 for gruesome death images observed throughout the sample. Additionally, Unresolved participants exhibited a right-hemispheric P3 asymmetry across picture categories, suggestive of continuously heightened vigilance/arousal. Together, these results suggest that Unresolved AAI status is associated with greater neurophysiological sensitivity to subtle reminders of loss that may disrupt ongoing mental function. (Psyc

  11. Accounting for sub-pixel variability of clouds and/or unresolved spectral variability, as needed, with generalized radiative transfer theory

    DOE PAGES

    Davis, Anthony B.; Xu, Feng; Collins, William D.

    2015-03-01

    Atmospheric hyperspectral VNIR sensing struggles with sub-pixel variability of clouds and limited spectral resolution mixing molecular lines. Our generalized radiative transfer model addresses both issues with new propagation kernels characterized by power-law decay in space.

  12. Issue Brief on Diversity

    ERIC Educational Resources Information Center

    Division on Developmental Disabilities, Council for Exceptional Children (NJ1), 2013

    2013-01-01

    During the past year, the Diversity Committee of the Division of Developmental Disabilities (DDD) Board worked with the Board and the Issues Committee Chair to develop an issue brief addressing diversity, its impact on the membership and the wider community that is served by the work of DDD, resulting in recommendations that will influence policy…

  13. Content Addressable Memory Project

    DTIC Science & Technology

    1990-11-01

    The Content Addressable M1-emory Project consists of the development of several experimental software systems on an AMT Distributed Array Processor...searching (database) compiler algorithms memory management other systems software) Linear C is an unlovely hybrid language which imports the CAM...memory from AMT’s operating system for the DAP; how- ever, other than this limitation, the memory management routines work exactly as their C counterparts

  14. Addressing viral resistance through vaccines

    PubMed Central

    Laughlin, Catherine; Schleif, Amanda; Heilman, Carole A

    2015-01-01

    Antimicrobial resistance is a serious healthcare concern affecting millions of people around the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance, but it is important to consider approaches to address this growing issue. While vaccination is a logical strategy, and has been shown to be successful many times over, next generation viral vaccines with a specific goal of curbing antiviral resistance will need to clear several hurdles including vaccine design, evaluation and implementation. This article suggests that a new model of vaccination may need to be considered: rather than focusing on public health, this model would primarily target sectors of the population who are at high risk for complications from certain infections. PMID:26604979

  15. Current issues and actions

    SciTech Connect

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the progress that has been made toward achieving full regulatory compliance at the Hanford Site. Ongoing compliance self-assessments, implementation of the Tri-Party Agreement, and public meetings continue to identify environmental compliance issues. These issues are discussed openly with the regulatory agencies and with the public to ensure that all environmental compliance issues are addressed.

  16. Methodological issues in the social cost of gambling studies.

    PubMed

    Walker, Douglas M

    2003-01-01

    The appropriate way to classify and measure the "social costs" of gambling is a very important, unresolved methodological issue that has been addressed by Collins and Lapsley (2000); Thompson, Gazel, and Rickman (1999); and Walker and Barnett (1999), among others. What should be included and excluded from social cost studies continues to be a controversial issue, as illustrated in the literature and recent conferences. This paper is an attempt to explain the "economics" conception of social costs in accessible language. By using a simple economic model and everyday examples, it shows that the economics methodology is better than the other methodologies currently available. There are four specific goals of the paper: (1) Discuss the importance of the social cost methodological debate and the state of research in the area; (2) Explain the Walker-Barnett definition of social cost in the context of a simple production possibilities frontier and indifference curve model; (3) Use simple illustrative examples to show why many of the alleged social costs should not be classified as such; and (4) Suggest a new method for analyzing the social costs and effects attributable to pathological gambling.

  17. Introduction to the Theory and Analysis of Resolved (and Unresolved) Neutron Resonances via SAMMY

    SciTech Connect

    Larson, N.

    2000-03-13

    Neutron cross-section data are important for two purposes: First, they provide insight into the nature of matter, increasing our understanding of fundamental physics. Second, they are needed for practical applications (e.g., for calculating when and how a reactor will become critical, or how much shielding is needed for storage of nuclear materials, or for medical applications). Neutron cross section data in the resolved-resonance region are generally obtained by time-of-flight experiments, which must be carefully analyzed if they are to be properly understood and utilized. In this report, important features of the analysis process are discussed, with emphasis on the particular techniques used in the analysis code SAMMY. Other features of the code are also described; these include such topics as calculation of group cross sections (including covariance matrices), generation and fitting of integral quantities, and extensions into the unresolved-resonance region and higher-energy regions.

  18. Introduction to the theory and analysis of resolved (and unresolved) neutron resonances via SAMMY

    SciTech Connect

    Larson, N.M.

    1998-02-01

    Neutron cross-section data are important for two distinct purposes: First, they provide insight into the nature of matter, thus assisting in the understanding of fundamental physics. Second, they are needed for practical applications (e.g., for calculating when and how a reactor will become critical, or how much shielding is needed for storage of nuclear materials, and for medical applications). Neutron cross section data in the resolved-resonance region are generally obtained by time-of-flight experiments, which must be carefully analyzed if they are to be properly understood and utilized. In this paper, important features of the analysis process are discussed, with emphasis on the particular techniques used in the analysis code SAMMY. Other features of the code are also described; these include such topics as calculation of group cross sections (including covariance matrices), generation and fitting of integral quantities, and extensions into the unresolved-resonance region and higher energy regions.

  19. Introduction to theory and analysis of resolved (and unresolved) neutron resonances via SAMMY

    SciTech Connect

    Larson, N.M.

    1998-07-01

    Neutron cross-section data are important for two distinct purposes: first, they provide insight into the nature of matter, thus assisting in the understanding of fundamental physics; second, they are needed for practical applications (e.g., for calculating when and how a reactor will become critical, or how much shielding is needed for storage of nuclear materials, and for medical applications). Neutron cross section data in the resolved-resonance region are generally obtained by time-of-flight experiments, which must be carefully analyzed if they are to be properly understood and utilized. In this paper, important features of the analysis process are discussed, with emphasis on the particular technique used in the analysis code SAMMY. Other features of the code are also described; these include such topics as calculation of group cross sections (including covariance matrices), generation and fitting of integral quantities, and extensions into the unresolved-resonance region and higher-energy regions.

  20. Average Neutron Total Cross Sections in the Unresolved Energy Range From ORELA High Resolutio Transmission Measurements

    SciTech Connect

    Derrien, H

    2004-05-27

    Average values of the neutron total cross sections of {sup 233}U, {sup 235}U, {sup 238}U, and {sup 239}Pu have been obtained in the unresolved resonance energy range from high-resolution transmission measurements performed at ORELA in the past two decades. The cross sections were generated by correcting the effective total cross sections for the self-shielding effects due to the resonance structure of the data. The self-shielding factors were found by calculating the effective and true cross sections with the computer code SAMMY for the same Doppler and resolution conditions as for the transmission measurements, using an appropriate set of resonance parameters. Our results are compared to results of previous measurements and to the current ENDF/B-VI data.

  1. LIMITS ON UNRESOLVED PLANETARY COMPANIONS TO WHITE DWARF REMNANTS OF 14 INTERMEDIATE-MASS STARS

    SciTech Connect

    Kilic, Mukremin; Gould, Andrew; Koester, Detlev

    2009-11-10

    We present Spitzer IRAC photometry of white dwarf remnants of 14 stars with M = 3-5 M{sub sun}. We do not detect mid-infrared excess around any of our targets. By demanding a 3sigma photometric excess at 4.5 mum for unresolved companions, we rule out planetary mass companions down to 5, 7, or 10 M {sub J} for 13 of our targets based on the Burrows et al. substellar cooling models. Combined with previous IRAC observations of white dwarf remnants of intermediate-mass stars, we rule out >=10M {sub J} companions around 40 white dwarfs and >=5M {sub J} companions around 10 white dwarfs.

  2. THE EFFECT OF UNRESOLVED BINARIES ON GLOBULAR CLUSTER PROPER-MOTION DISPERSION PROFILES

    SciTech Connect

    Bianchini, P.; Norris, M. A.; Ven, G. van de; Schinnerer, E.; Bellini, A.; Marel, R. P. van der; Watkins, L. L.; Anderson, J.

    2016-03-20

    High-precision kinematic studies of globular clusters (GCs) require an accurate knowledge of all possible sources of contamination. Among other sources, binary stars can introduce systematic biases in the kinematics. Using a set of Monte Carlo cluster simulations with different concentrations and binary fractions, we investigate the effect of unresolved binaries on proper-motion dispersion profiles, treating the simulations like Hubble Space Telescope proper-motion samples. Since GCs evolve toward a state of partial energy equipartition, more-massive stars lose energy and decrease their velocity dispersion. As a consequence, on average, binaries have a lower velocity dispersion, since they are more-massive kinematic tracers. We show that, in the case of clusters with high binary fractions (initial binary fractions of 50%) and high concentrations (i.e., closer to energy equipartition), unresolved binaries introduce a color-dependent bias in the velocity dispersion of main-sequence stars of the order of 0.1–0.3 km s{sup −1} (corresponding to 1%−6% of the velocity dispersion), with the reddest stars having a lower velocity dispersion, due to the higher fraction of contaminating binaries. This bias depends on the ability to distinguish binaries from single stars, on the details of the color–magnitude diagram and the photometric errors. We apply our analysis to the HSTPROMO data set of NGC 7078 (M15) and show that no effect ascribable to binaries is observed, consistent with the low binary fraction of the cluster. Our work indicates that binaries do not significantly bias proper-motion velocity-dispersion profiles, but should be taken into account in the error budget of kinematic analyses.

  3. Factors affecting the duration effect in pitch perception for unresolved complex tones

    NASA Astrophysics Data System (ADS)

    White, Louise J.; Plack, Christopher J.

    2003-12-01

    Previous research has shown that fundamental frequency (F0) discrimination thresholds for complex tones containing unresolved harmonics decrease as the duration of the tone increases [White and Plack, J. Acoust. Soc. Am. 103, 2051-2063 (1998)]. In this paper F0 discrimination was measured as a function of duration for complexes with F0s of 62.5, 125, and 250 Hz, bandpass filtered into two spectral regions (2750-3750 and 5500-7500 Hz). The harmonics were summed either in sine phase (SINE) or with alternating sine-cosine phase (ALT), which affects the envelope of the waveform and the pitch of the complex. Tone duration was 20, 40, 80, and 160 ms. The improvement in F0 discrimination with duration increased with decreasing F0. When harmonics where spectrally filtered between 2750 and 3750 Hz, for complexes with an F0 of 62.5 Hz, F0 discrimination thresholds decreased from approximately 30% for a 20-ms tone to approximately 3% for a 160-ms tone. For complexes with an F0 of 250 Hz, thresholds decreased from 3% for a 20-ms tone to 1% for a 160-ms tone: a lower envelope repetition rate led to a larger change in performance with increasing duration. The phase manipulation also affected the size of the duration effect, in that the effect was less for an ALT complex compared to a SINE complex with the same F0, consistent with the change in envelope repetition rate. Overall, the results suggest that for unresolved complex tones it is primarily envelope repetition rate, not spectral region, that determines both the F0 discrimination threshold and the size of the duration effect.

  4. X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.

    PubMed

    Hu, H; Haas, S A; Chelly, J; Van Esch, H; Raynaud, M; de Brouwer, A P M; Weinert, S; Froyen, G; Frints, S G M; Laumonnier, F; Zemojtel, T; Love, M I; Richard, H; Emde, A-K; Bienek, M; Jensen, C; Hambrock, M; Fischer, U; Langnick, C; Feldkamp, M; Wissink-Lindhout, W; Lebrun, N; Castelnau, L; Rucci, J; Montjean, R; Dorseuil, O; Billuart, P; Stuhlmann, T; Shaw, M; Corbett, M A; Gardner, A; Willis-Owen, S; Tan, C; Friend, K L; Belet, S; van Roozendaal, K E P; Jimenez-Pocquet, M; Moizard, M-P; Ronce, N; Sun, R; O'Keeffe, S; Chenna, R; van Bömmel, A; Göke, J; Hackett, A; Field, M; Christie, L; Boyle, J; Haan, E; Nelson, J; Turner, G; Baynam, G; Gillessen-Kaesbach, G; Müller, U; Steinberger, D; Budny, B; Badura-Stronka, M; Latos-Bieleńska, A; Ousager, L B; Wieacker, P; Rodríguez Criado, G; Bondeson, M-L; Annerén, G; Dufke, A; Cohen, M; Van Maldergem, L; Vincent-Delorme, C; Echenne, B; Simon-Bouy, B; Kleefstra, T; Willemsen, M; Fryns, J-P; Devriendt, K; Ullmann, R; Vingron, M; Wrogemann, K; Wienker, T F; Tzschach, A; van Bokhoven, H; Gecz, J; Jentsch, T J; Chen, W; Ropers, H-H; Kalscheuer, V M

    2016-01-01

    X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified. Yet, a large number of families mapping to the X-chromosome remained unresolved suggesting that more XLID genes or loci are yet to be identified. Here, we have investigated 405 unresolved families with XLID. We employed massively parallel sequencing of all X-chromosome exons in the index males. The majority of these males were previously tested negative for copy number variations and for mutations in a subset of known XLID genes by Sanger sequencing. In total, 745 X-chromosomal genes were screened. After stringent filtering, a total of 1297 non-recurrent exonic variants remained for prioritization. Co-segregation analysis of potential clinically relevant changes revealed that 80 families (20%) carried pathogenic variants in established XLID genes. In 19 families, we detected likely causative protein truncating and missense variants in 7 novel and validated XLID genes (CLCN4, CNKSR2, FRMPD4, KLHL15, LAS1L, RLIM and USP27X) and potentially deleterious variants in 2 novel candidate XLID genes (CDK16 and TAF1). We show that the CLCN4 and CNKSR2 variants impair protein functions as indicated by electrophysiological studies and altered differentiation of cultured primary neurons from Clcn4(-/-) mice or after mRNA knock-down. The newly identified and candidate XLID proteins belong to pathways and networks with established roles in cognitive function and intellectual disability in particular. We suggest that systematic sequencing of all X-chromosomal genes in a cohort of patients with genetic evidence for X-chromosome locus involvement may resolve up to 58% of Fragile X-negative cases.

  5. Inference of Unresolved Point Sources at High Galactic Latitudes Using Probabilistic Catalogs

    NASA Astrophysics Data System (ADS)

    Daylan, Tansu; Portillo, Stephen K. N.; Finkbeiner, Douglas P.

    2017-04-01

    The detection of point sources in images is a fundamental operation in astrophysics, and is crucial for constraining population models of the underlying point sources or characterizing the background emission. Standard techniques fall short in the crowded-field limit, losing sensitivity to faint sources and failing to track their covariance with close neighbors. We construct a Bayesian framework to perform inference of faint or overlapping point sources. The method involves probabilistic cataloging, where samples are taken from the posterior probability distribution of catalogs consistent with an observed photon count map. In order to validate our method, we sample random catalogs of the gamma-ray sky in the direction of the North Galactic Pole (NGP) by binning the data in energy and point-spread function classes. Using three energy bins spanning 0.3–1, 1–3, and 3–10 GeV, we identify {270}-10+30 point sources inside a 40^\\circ × 40^\\circ region around the NGP above our point-source inclusion limit of 3× {10}-11 cm‑2 s‑1 sr‑1 GeV‑1 at the 1–3 GeV energy bin. Modeling the flux distribution as a power law, we infer the slope to be -{1.92}-0.05+0.07 and estimate the contribution of point sources to the total emission as {18}-2+2%. These uncertainties in the flux distribution are fully marginalized over the number as well as the spatial and spectral properties of the unresolved point sources. This marginalization allows a robust test of whether the apparently isotropic emission in an image is due to unresolved point sources or of truly diffuse origin.

  6. Developing Social Marketing Capacity to Address Health Issues

    ERIC Educational Resources Information Center

    Whitelaw, S.; Smart, E.; Kopela, J.; Gibson, T.; King, V.

    2011-01-01

    Purpose: Social marketing is increasingly being seen as a potentially effective means of pursuing health education practice generally and within various specific areas such as mental health and wellbeing and more broadly in tackling health inequalities. This paper aims to report and reflect on the authors' experiences of undertaking a health…

  7. Obesity in pregnancy: addressing the issues at the booking appointment.

    PubMed

    Haken, Clara; Fitzsimons, Kate

    2011-03-01

    The recently published Centre for Maternal and Child Enquiries (CMACE) report, Maternal Obesity in the UK: Findings from a National Project, has provided new information on how often we are caring for women who have a body mass index (BMI) of 35 or more, who these women are, the complications and consequences associated with obesity during pregnancy and the preparedness of maternity services to meet these women's needs. Focusing on booking, this article highlights some of the study's key recommendations and discusses the implications for midwives. Accurate calculation of BMI, discussion of dietary advice including supplementation, risk assessment and referral on are all considerations for this consultation.

  8. Addressing the Issue of Teaching English as a Lingua Franca

    ERIC Educational Resources Information Center

    Kuo, I-Chun

    2006-01-01

    The status of English as a lingua franca (ELF) has become an increasingly popular discourse in Applied Linguistics and current ELT. It has been suggested that native speakers and their Englishes have become relatively unimportant in international communication and that research interests should now fall on non-native speakers and their use of…

  9. Advances in Pediatric Asthma in 2010: Addressing the Major Issues

    PubMed Central

    Szefler, Stanley J.

    2010-01-01

    Last year’s Advances in Pediatric Asthma concluded with the following statement “If we can close these [remaining] gaps through better communication, improvements in the health care system and new insights into treatment, we will move closer to better methods to intervene early in the course of the disease and induce clinical remission as quickly as possible in most children”. This year’s summary will focus on recent advances in pediatric asthma that take steps moving forward as reported in Journal of Allergy and Clinical Immunology publications in 2010. Some of those recent reports show us how to improve asthma management through steps to better understand the natural history of asthma, individualize asthma care, reduce asthma exacerbations, manage inner city asthma, and some potential new ways to use available medications to improve asthma control. It is clear that we have made many significant gains in managing asthma in children but we have a ways to go to prevent asthma exacerbations, alter the natural history of the disease, and to reduce health disparities in asthma care. Perhaps new directions in personalized medicine and improved health care access and communication will help maintain steady progress in alleviating the burden of this disease in children, especially young children. PMID:21211645

  10. New smart materials to address issues of structural health monitoring.

    SciTech Connect

    Chaplya, Pavel Mikhail

    2004-12-01

    Nuclear weapons and their storage facilities may benefit from in-situ structural health monitoring systems. Appending health-monitoring functionality to conventional materials and structures has been only marginally successful. The purpose of this project was to evaluate feasibility of a new smart material that includes self-sensing health monitoring functions similar to that of a nervous system of a living organism. Reviews of current efforts in the fields of heath-monitoring, nanotechnology, micro-electromechanical systems (MEMS), and wireless sensor networks were conducted. Limitations of the current nanotechnology methods were identified and new approaches were proposed to accelerate the development of self-sensing materials. Wireless networks of MEMS sensors have been researched as possible prototypes of self-sensing materials. Sensor networks were also examined as enabling technologies for dense data collection techniques to be used for validation of numerical methods and material parameter identification. Each grain of the envisioned material contains sensors that are connected in a dendritic manner similar to networks of neurons in a nervous system. Each sensor/neuron can communicate with the neighboring grains. Both the state of the sensor (on/off) and the quality of communication signal (speed/amplitude) should indicate not only a presence of a structural defect but the nature of the defect as well. For example, a failed sensor may represent a through-grain crack, while a lost or degraded communication link may represent an inter-granular crack. A technology to create such material does not exist. While recent progress in the fields of MEMS and nanotechnology allows to envision these new smart materials, it is unrealistic to expect creation of self-sensing materials in the near future. The current state of MEMS, nanotechnology, communication, sensor networks, and data processing technologies indicates that it will take more than ten years for the technologies to mature enough to make self-sensing materials a reality. Nevertheless, recent advances in the field of nanotechnology demonstrate that nanotubes, nanorods, and nanoparticles of carbon, boron and other materials have remarkable mechanical and electrical properties. This would provide. for a plethora of potential applications including self-sensing materials. Record strength-to-weight ratios, ballistic conductivity, and sensing capabilities (i.e., piezo- resistance and piezoelectricity) have been reported for carbon nanotubes. The first transistors, sensors, and actuators have been made from the carbon nanotubes and other nanomaterials. However, nanomaterials are notoriously difficult to manipulate into useful geometries. Nano-manufacturing processes often produce bundles or random networks of nanostructured materials. Samples of the material are then manipulated with advanced microscopy tools to measure properties or to create a single device. This is a laborious and time consuming process. An often overlooked property of the manufactured nanotube bundles is their similarity to the dendritic structure of neural networks with a great quantity of interconnects that may serve as initiation sites for artificial neurons in a self-sensing material nervous system. To accelerate the development of self-sensing materials, future research should concentrate on naturally occurring dendritic nano-structures. While self-sensing materials with subgrain size sensors (scale of micrometers) remain in the realm of basic research, meso-scale (millimeters to centimeters) sensors and their networks are in the state of mature research and have begun to find their way into commercial applications. Macro-scale (centimeters to decimeters) sensors and their networks are commercially available from various sources. The majority of applications that employ sensor networks are driven by the needs of the Department of Defense. Widespread adaptation of sensor networks has been limited by, on one hand, the sensor's high cost of design, development, and deployment, and on the other hand, a lack of reliable long-term power sources. Solutions to both of these drawbacks require significant investments driven by real-life applications. Possible applications for sensor networks at Sandia National Laboratories include dense data collection techniques for validation of numerical methods and material parameter identification. For example, an array of distributed wireless macro-scale sensors can record the structural response of soils and reinforced concrete during explosive loading. Another example is an array of surface mounted micro-sensors that can record the modal response of nuclear weapon components. The collected data would be used to validate existing numerical codes and to identify new physical mechanisms to improve Sandia's computational models.

  11. Addressing Machining Issues for the Intermetallic Compound 60-NITINOL

    NASA Technical Reports Server (NTRS)

    Stanford, Malcolm K.; Wozniak, Walter A.; McCue, Terry R.

    2012-01-01

    60-NITINOL (60 wt.% Ni - 40 wt.% Ti) is being studied as a material for advanced aerospace components. Frequent wire breakage during electrical-discharge machining of this material was investigated. The studied material was fabricated from hot isostatically pressed 60-NITINOL powder obtained through a commercial source. Bulk chemical analysis of the material showed that the composition was nominal but had relatively high levels of certain impurities, including Al and O. It was later determined that Al2O3 particles had contaminated the material during the hot isostatic pressing procedure and that these particles were the most likely cause of the wire breakage. The results of this investigation highlight the importance of material cleanliness to its further implementation.

  12. Addressing Issues of Workplace Harassment: Counseling the Targets.

    ERIC Educational Resources Information Center

    Lewis, Jacqueline; Coursol, Diane; Wahl, Kay Herting

    2002-01-01

    Workplace harassment includes dysfunctional personal interactions characterized by bullying behaviors, personal attacks, and attempts to denigrate others. Targets of workplace harassment may experience stress, depression, low self-esteem, loss of sleep, and even posttraumatic stress disorder. Strategies that counselors can use to work effectively…

  13. Addressing the amorphous content issue in quantitative phase analysis

    NASA Astrophysics Data System (ADS)

    Cline, J. P.; Dreele, R. B. Von; Winburn, R.; Stephens, P. W.; Filliben, J. J.

    2011-07-01

    A novel method is used to determine the amorphous content in the certification of NIST standard reference material (SRM) 676a (corundum). Extrapolation of diffraction measurements from mixtures with Si powders of varying surface-to-volume ratio show that approximately 1% by weight of SRM 676a is amorphous.

  14. A Strategic Model to Address Issues of Student Achievement

    ERIC Educational Resources Information Center

    Fontana, Leonard; Johnson, Elease; Green, Peggy; Macia, Jose; Wright, Ted; Daniel, Yanick; Distefano Diaz, Mary F.; Obenauf, Steve

    2006-01-01

    This article describes an interactive and collaborative strategic planning process by a community college in which student retention and success became a focus of a re-accreditation endeavor. The underlying assumption of this strategic planning effort was that engaging all groups that have a stake in student retention at the beginning of the…

  15. Current Issues Concerning Clinical Optometric Education. Keynote Address.

    ERIC Educational Resources Information Center

    Imperato, Pascal James

    1996-01-01

    Clinical optometric education is in flux. It must meet the challenges of advances in bioscience, newer diagnostic and therapeutic modalities, a changing health care environment, and interdisciplinary learning for problem solving; engender social responsibility; promote good provider-patient relations; stress primary care; and emphasize prevention.…

  16. Addressing criminality in childhood: is responsivity the central issue?

    PubMed

    Nee, Claire; Ellis, Tom; Morris, Paul; Wilson, Amy

    2013-11-01

    The responsivity principle is the third element of the now well-established risk-need-responsivity (RNR) model of offender rehabilitation. Accruing evidence suggests it is often sacrificed in intervention programs. We aim to demonstrate the central importance of this principle when designing offender interventions by describing the results of a successful, highly responsive intervention for very young children (aged 7 upward) who have offended. A small slice of the offending population as a whole, child offenders are nevertheless tomorrow's serious, violent, and prolific lawbreakers, yet little is understood about what reduces their risk. Recent developments on responsivity are reviewed, before presenting the evaluation indicating significant and sustained drops in risk of recidivism. In-program factors such as the nature and dosage of interventions are examined, alongside outcome data. The article discusses how RNR and other models might apply to this particularly young and underresearched age group.

  17. Student Academic Dishonesty: Are Collegiate Institutions Addressing the Issue?

    ERIC Educational Resources Information Center

    Aaron, Ronald M.

    1992-01-01

    Surveyed student affairs officers (n=175) from four-year colleges and community colleges to determine extent to which institutions have developed programs to ensure academic integrity. Results indicated almost all institutions possessed printed codes of academic integrity and procedural guidelines. Four-year colleges were significantly more likely…

  18. Addressing Poverty Issues in Christian Schools: Teachers' Perspectives

    ERIC Educational Resources Information Center

    Bankston, Catherine

    2015-01-01

    The purpose of Christian education is to incorporate Biblical values in the curriculum, and one essential message in the Bible is to reach out and liberate the poor. Through interviews, writing protocols, a focus group meeting, and document analysis, this narrative study focuses on the question of how do Christian educators create pedagogical…

  19. Obama address touches on research, energy, and environmental issues

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-02-01

    President Barack Obama's State of the Union message, delivered on 24 January, touched on the need for basic research, energy production, support for clean energy, and environmental protection, but it included just one passing reference to climate change. In addition, the speech made no note of the Administration's recent denial of a controversial application for the Keystone XL pipeline to transport crude oil from Canada to the United States and made just an elliptical reference regarding the bankrupt Solyndra Corporation, which the administration had touted as a clean energy company. Innovation "demands basic research," Obama said, adding that Congress should not "gut these investments in our budget." Noting that one promise for innovation is American-made energy, Obama said he is directing the administration to "open more than 75% of our potential offshore oil and gas resources."

  20. Assessing Rural Coalitions That Address Safety and Health Issues

    ERIC Educational Resources Information Center

    Burgus, Shari; Schwab, Charles; Shelley, Mack

    2012-01-01

    Community coalitions can help national organizations meet their objectives. Farm Safety 4 Just Kids depends on coalitions of local people to deliver farm safety and health educational programs to children and their families. These coalitions are called chapters. An evaluation was developed to identify individual coalition's strengths and…

  1. A Model for Addressing Spiritual Issues in Counseling.

    ERIC Educational Resources Information Center

    Russo, Thomas J.

    1984-01-01

    Discusses the hesitancy of counselors and psychotherapists to approach the spiritual concerns of clients. Proposes a counseling and psychotherapy training model that contains discrete yet continuous levels of learning. The holistic epistemology of Gregory Bateson is used to derive guiding theoretical principles for the training model. (Author/JAC)

  2. How the National Estuary Programs Address Environmental Issues

    EPA Pesticide Factsheets

    Estuaries face many challenges including, alteration of natural hydrologic flows, aquatic nuisance species, climate change, declines in fish and wildlife populations, habitat loss and degradation, nutrient loads, pathogens, stormwater and toxics.

  3. Integrated strategy urged to address coastal contamination issues

    USGS Publications Warehouse

    Swarzenski, Peter W.; Kvenvolden, Keith A.; Horowitz, Arthur J.; Buchholtz ten Brink, Marilyn

    2001-01-01

    Coastal bays and estuaries are well known for their intrinsic recreational and economic value, yet these ecosystems are also among our most troubled natural environments. Urban development, agriculture, and shipping are just a few examples of human activities that can cause a wide range of deleterious changes within the coastal environment. These alterations, however, occur simultaneously with cycles of natural variability such as climate change. To effectively manage coastal ecosystems, we need to be able to carefully distinguish between anthropogenic and natural causes of change.

  4. The breast cancer research scandal: addressing the issues.

    PubMed Central

    Weijer, C

    1995-01-01

    The three claims put forward by Dr. Roger Poisson to rationalize his enrollment of ineligible subjects in clinical trials do not justify research fraud. None the less, certain lessons for the conduct of clinical research can be learned from the affair: experimental therapies should be made available to technically ineligible subjects when no effective therapy exists for their disease; further research must investigate the possible benefits of clinical-trial participation; broadly based, pragmatic trials must be regarded as the ideal model; and each eligibility criterion in a clinical-trial protocol should be justified. PMID:7736369

  5. Ethical Issues in Addressing Inequity in/through ESL Research

    ERIC Educational Resources Information Center

    Lee, Ena

    2011-01-01

    This article outlines a researcher's struggles with conducting "ethical" research when her case study reveals racializations faced by a minority teacher in a Canadian ESL program. How might becoming privy to research participants' experiences of inequity in ESL education complicate the notion of research ethics when "doing the right…

  6. SLIIDEA: Positive Approaches for Addressing Behavioral Issues. inForum

    ERIC Educational Resources Information Center

    Misra, Sunil

    2006-01-01

    When Congress passed the Individuals with Disabilities Education Act (IDEA) in 1997, it authorized an evaluation to track progress at the state and local levels on the legislative goals of IDEA. The U.S. Department of Education's Office of Special Education Programs (OSEP) commissioned a national longitudinal study, the Study of State and Local…

  7. Addressing Issues of Power, Justice, and Privilege in Literacy Instruction

    ERIC Educational Resources Information Center

    Tate, Stacie L.

    2014-01-01

    Tate applauds Rogers's use of teacher research to illustrate how literacy coaches and teachers can approach an accelerative literacy framework with a critical literacy lens. Citing her own work, as well as the work of other critical literacy educators, Tate reminds readers that teacher research is a careful plan that encompasses the power of…

  8. Importance of Addressing Sexuality in Certified Rehabilitation Counselor Practice

    ERIC Educational Resources Information Center

    Kazukauskas, Kelly A.; Lam, Chow S.

    2009-01-01

    This study investigated Certified Rehabilitation Counselors' (CRCs) beliefs about the importance of addressing sexuality issues during rehabilitation. A modified version of the Family Life Sex Education Goals Questionnaire (FLSEGQ) was completed by 199 CRCs to determine which issues CRCs believe are most important to address. Six sexuality-related…

  9. Content addressable memory project

    NASA Technical Reports Server (NTRS)

    Hall, J. Storrs; Levy, Saul; Smith, Donald E.; Miyake, Keith M.

    1992-01-01

    A parameterized version of the tree processor was designed and tested (by simulation). The leaf processor design is 90 percent complete. We expect to complete and test a combination of tree and leaf cell designs in the next period. Work is proceeding on algorithms for the computer aided manufacturing (CAM), and once the design is complete we will begin simulating algorithms for large problems. The following topics are covered: (1) the practical implementation of content addressable memory; (2) design of a LEAF cell for the Rutgers CAM architecture; (3) a circuit design tool user's manual; and (4) design and analysis of efficient hierarchical interconnection networks.

  10. Problem Solvers: Solutions--The Inaugural Address

    ERIC Educational Resources Information Center

    Dause, Emily

    2014-01-01

    Fourth graders in Miss Dause's and Mrs. Hicks's mathematics classes at South Mountain Elementary School in Dillsburg, Pennsylvania, worked with the data from the Inauagural Address problem that was previously published published in the February 2013 issue of "Teaching Children Mathematics". This activity allowed students to showcase…

  11. How Sociology Texts Address Gun Control

    ERIC Educational Resources Information Center

    Tonso, William R.

    2004-01-01

    William R. Tonso has chosen an issue that he knows something about to examine how sociology textbooks address controversy. Appealing for gun control is fashionable, but it is at odds with a fondness that ordinary Americans have for their firearms--one that is supported by a growing body of research on deterrence to crime. There are two sides to…

  12. EPA Addresses Environmental Justice in Houston

    EPA Pesticide Factsheets

    DALLAS - (Oct. 8, 2015) Today, the U.S. Environmental Protection Agency (EPA) announced Texas Environmental Justice Advocacy Services (t.e.j.a.s.) was selected as a grant recipient to address environmental justice (EJ) issues in the Manchester area

  13. Addressing Deaf Culture in the Classroom.

    ERIC Educational Resources Information Center

    Pagliaro, Claudia

    2001-01-01

    The importance of recognizing the culture of deaf people is often overlooked when addressing issues of student diversity in the schools. Including the culture of deaf students can add vitality and energy to the educational environment, providing an alternative and unique perspective. This paper describes deafness, explains deaf culture, and…

  14. Detection of Spatially Unresolved (Nominally Sub-Pixel) Submerged and Surface Targets Using Hyperspectral Data

    DTIC Science & Technology

    2012-09-01

    Nominally Sub- Pixel) Submerged and Surface Targets Using Hyperspectral Data 5. FUNDING NUMBERS 6. AUTHOR( S ) Christopher B. Burt 7. PERFORMING...ORGANIZATION NAME( S ) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...MONITORING AGENCY NAME( S ) AND ADDRESS(ES) Remote Sensing Center, Naval Postgraduate School 10. SPONSORING/MONITORING AGENCY REPORT NUMBER 11

  15. Are CSF Biomarkers Useful as Prognostic Indicators in Diagnostically Unresolved Cognitively Impaired Patients in a Normal Clinical Setting

    PubMed Central

    Schjønning Nielsen, Malene; Simonsen, Anja Hviid; Siersma, Volkert; Hasselbalch, Steen Gregers; Høgh, Peter

    2016-01-01

    Background Despite an extensive evaluation program, patients may remain diagnostically unresolved with regard to the etiology of their cognitive dysfunction. Cerebrospinal fluid neuroinflammation and Alzheimer disease (AD) biomarkers may act as indicators of neurodegenerative disorders in diagnostically unresolved patients. Methods Data on 348 patients were retrospectively evaluated. All participants had a standardized diagnostic workup and follow-up in a memory clinic. Results Aβ42 levels and Aβ42/p-tau ratios were reduced and levels of t-tau and p-tau as well as the t-tau × p-tau/Aβ42 ratio were elevated in diagnostically unresolved patients who clinically progressed, compared to a stable group. No differences in neuroinflammatory parameters were found. Conclusion AD biomarkers - in particular the Aβ42/p-tau ratio, but not neuroinflammatory parameters - predicted clinical progression, regardless of etiology. PMID:27843444

  16. Caregiver unresolved loss and abuse and child behavior problems: intergenerational effects in a high-risk sample.

    PubMed

    Zajac, Kristyn; Kobak, Roger

    2009-01-01

    This study examines the intergenerational effects of caregivers' unresolved loss and abuse on children's behavior problems from middle childhood to early adolescence in an economically disadvantaged sample. One hundred twenty-four caregivers completed the Adult Attachment Interview (AAI) and a lifetime trauma interview during the age 13 wave of the study. Child behavior problems were assessed at four time points (ages 6, 8, 10, and 13) with teacher-reported Child Behavior Checklist total problem scales. The children of insecure caregivers with unresolved loss showed a consistent pattern of increased behavior problems from middle childhood to early adolescence. Caregivers' AAI status accounted for more variance in child behavior problems than did an alternative model of caregiver psychopathology (depression and dissociation). The results extend the literature on the effects of caregiver unresolved states of mind beyond infancy to older children and adolescents.

  17. Content addressable memory project

    NASA Technical Reports Server (NTRS)

    Hall, Josh; Levy, Saul; Smith, D.; Wei, S.; Miyake, K.; Murdocca, M.

    1991-01-01

    The progress on the Rutgers CAM (Content Addressable Memory) Project is described. The overall design of the system is completed at the architectural level and described. The machine is composed of two kinds of cells: (1) the CAM cells which include both memory and processor, and support local processing within each cell; and (2) the tree cells, which have smaller instruction set, and provide global processing over the CAM cells. A parameterized design of the basic CAM cell is completed. Progress was made on the final specification of the CPS. The machine architecture was driven by the design of algorithms whose requirements are reflected in the resulted instruction set(s). A few of these algorithms are described.

  18. Controversial issues in CKD clinical practice: position statement of the CKD-treatment working group of the Italian Society of Nephrology.

    PubMed

    Bellizzi, Vincenzo; Conte, Giuseppe; Borrelli, Silvio; Cupisti, Adamasco; De Nicola, Luca; Di Iorio, Biagio R; Cabiddu, Gianfranca; Mandreoli, Marcora; Paoletti, Ernesto; Piccoli, Giorgina B; Quintaliani, Giuseppe; Ravera, Maura; Santoro, Domenico; Torraca, Serena; Minutolo, Roberto

    2017-04-01

    This position paper of the study group "Conservative treatment of Chronic Kidney Disease-CKD" of the Italian Society of Nephrology addresses major practical, unresolved, issues related to the conservative treatment of chronic renal disease. Specifically, controversial topics from everyday clinical nephrology practice which cannot find a clear, definitive answer in the current literature or in nephrology guidelines are discussed. The paper reports the point of view of the study group. Concise and practical advice is given on several common issues: renal biopsy in diabetes; dual blockade of the renin-angiotensin-aldosterone system (RAAS); management of iron deficiency; low protein diet; dietary salt intake; bicarbonate supplementation; treatment of obesity; the choice of conservative therapy vs. dialysis. For each topic synthetic statements, guideline-style, are reported.

  19. M Dwarfs From The SDSS, 2MASS and WISE Surveys: Identification, Characterisation and Unresolved Ultracool Companionship

    NASA Astrophysics Data System (ADS)

    Cook, Neil James

    2016-08-01

    The aim of this thesis is to use a cross-match between WISE, 2MASS and SDSS to identify a large sample of M dwarfs. Through the careful characterisation and quality control of these M dwarfs I aim to identify rare systems (i.e. unresolved UCD companions, young M dwarfs, late M dwarfs and M dwarfs with common proper motion companions). Locating ultracool companions to M dwarfs is important for constraining low-mass formation models, the measurement of substellar dynamical masses and radii, and for testing ultracool evolutionary models. This is done by using an optimised method for identifying M dwarfs which may have unresolved ultracool companions. To do this I construct a catalogue of 440 694 M dwarf candidates, from WISE, 2MASS and SDSS, based on optical- and near-infrared colours and reduced proper motion. With strict reddening, photometric and quality constraints I isolate a sub-sample of 36 898 M dwarfs and search for possible mid-infrared M dwarf + ultracool dwarf candidates by comparing M dwarfs which have similar optical/near-infrared colours (chosen for their sensitivity to effective temperature and metallicity). I present 1 082 M dwarf + ultracool dwarf candidates for follow-up. Using simulated ultracool dwarf companions to M dwarfs, I estimate that the occurrence of unresolved ultracool companions amongst my M dwarf + ultracool dwarf candidates should be at least four times the average for my full M dwarf catalogue. I discuss yields of candidates based on my simulations. The possible contamination and bias from misidentified M dwarfs is then discussed, from chance alignments with other M dwarfs and UCDs, from chance alignments with giant stars, from chance alignments with galaxies, and from blended systems (via visual inspection). I then use optical spectra from LAMOST to spectral type a subset of my M dwarf + ultracool dwarf candidates. These candidates need confirming as true M dwarf + ultracool dwarf systems thus I present a new method I developed to

  20. Resolution of thermal-hydraulic safety and licensing issues for the system 80+{sup {trademark}} design

    SciTech Connect

    Carpentino, S.E.; Ritterbusch, S.E.; Schneider, R.E.

    1995-09-01

    The System 80+{sup {trademark}} Standard Design is an evolutionary Advanced Light Water Reactor (ALWR) with a generating capacity of 3931 MWt (1350 MWe). The Final Design Approval (FDA) for this design was issued by the Nuclear Regulatory Commission (NRC) in July 1994. The design certification by the NRC is anticipated by the end of 1995 or early 1996. NRC review of the System 80+ design has involved several new safety issues never before addressed in a regulatory atmosphere. In addition, conformance with the Electric Power Research Institute (EPRI) ALWR Utility Requirements Document (URD) required that the System 80+ plant address nuclear industry concerns with regard to design, construction, operation and maintenance of nuclear power plants. A large number of these issues/concerns deals with previously unresolved generic thermal-hydraulic safety issues and severe accident prevention and mitigation. This paper discusses the thermal-hydraulic analyses and evaluations performed for the System 80+ design to resolve safety and licensing issues relevant to both the Nuclear Stream Supply System (NSSS) and containment designs. For the NSSS design, the Safety Depressurization System mitigation capability and resolution of the boron dilution concern are described. Examples of containment design issues dealing with containment shell strength, robustness of the reactor cavity walls and hydrogen mixing under severe accident conditions are also provided. Finally, the overall approach used in the application of NRC`s new (NUREG-1465) radiological source term for System 80+ evaluation is described. The robustness of the System 80+ containment design to withstand severe accident consequences was demonstrated through detailed thermal-hydraulic analyses and evaluations. This advanced design to shown to meet NRC severe accident policy goals and ALWR URD requirements without any special design features and unnecessary costs.

  1. Thermal-hydraulic design issues and analysis for the ITER (International Thermonuclear Experimental Reactor) divertor

    SciTech Connect

    Koski, J.A.; Watson, R.D. ); Hassanien, A.M. ); Goranson, P.L. . Fusion Engineering Design Center); Salmonson, J.C. . Special Projects)

    1990-01-01

    Critical Heat Flux (CHF), also called burnout, is one of the major design limits for water-cooled divertors in tokamaks. Another important design issue is the correct thermal modeling of the divertor plate geometry where heat is applied to only one side of the plate and highly subcooled flow boiling in internal passages is used for heat removal. This paper discusses analytical techniques developed to address these design issues, and the experimental evidence gathered in support of the approach. Typical water-cooled divertor designs for the International Thermonuclear Experimental Reactor (ITER) are analyzed, and design margins estimated. Peaking of the heat flux at the tube-water boundary is shown to be an important issue, and design concerns which could lead to imposing large design safety margins are identified. The use of flow enhancement techniques such as internal twisted tapes and fins are discussed, and some estimates of the gains in the design margin are presented. Finally, unresolved issues and concerns regarding hydraulic design of divertors are summarized, and some experiments which could help the ITER final design process identified. 23 refs., 10 figs.

  2. Neutron Cross Section Processing Methods for Improved Integral Benchmarking of Unresolved Resonance Region Evaluations

    NASA Astrophysics Data System (ADS)

    Walsh, Jonathan A.; Forget, Benoit; Smith, Kord S.; Brown, Forrest B.

    2016-03-01

    In this work we describe the development and application of computational methods for processing neutron cross section data in the unresolved resonance region (URR). These methods are integrated with a continuous-energy Monte Carlo neutron transport code, thereby enabling their use in high-fidelity analyses. Enhanced understanding of the effects of URR evaluation representations on calculated results is then obtained through utilization of the methods in Monte Carlo integral benchmark simulations of fast spectrum critical assemblies. First, we present a so-called on-the-fly (OTF) method for calculating and Doppler broadening URR cross sections. This method proceeds directly from ENDF-6 average unresolved resonance parameters and, thus, eliminates any need for a probability table generation pre-processing step in which tables are constructed at several energies for all desired temperatures. Significant memory reduction may be realized with the OTF method relative to a probability table treatment if many temperatures are needed. Next, we examine the effects of using a multi-level resonance formalism for resonance reconstruction in the URR. A comparison of results obtained by using the same stochastically-generated realization of resonance parameters in both the single-level Breit-Wigner (SLBW) and multi-level Breit-Wigner (MLBW) formalisms allows for the quantification of level-level interference effects on integrated tallies such as keff and energy group reaction rates. Though, as is well-known, cross section values at any given incident energy may differ significantly between single-level and multi-level formulations, the observed effects on integral results are minimal in this investigation. Finally, we demonstrate the calculation of true expected values, and the statistical spread of those values, through independent Monte Carlo simulations, each using an independent realization of URR cross section structure throughout. It is observed that both probability table

  3. The Oculus-ASR: An Orbiting Nanosatellite Testbed for Unresolved Object Characterization

    NASA Astrophysics Data System (ADS)

    King, L.; LaSarge, J. A.

    2012-09-01

    The Oculus-ASR is a 70-kg-nanosatellite specifically designed to advance USAF space situational awareness by providing calibration opportunities and validation techniques for AMOS's telescopic non-resolved object characterization program. This paper will describe the design and capabilities of the Oculus-ASR, its concept of operations, and report on its initial ground optical characterization. Nearly every object orbiting the Earth, when viewed using all but the largest ground-based telescopes, appear as unresolved point sources of light. Although these unresolved objects seem to be featureless, it may be possible to determine characteristics related to an object's attitude and/or rotation rate by analyzing the spectral and temporal content of reflected sunlight off of the object. For instance, a faceted rotating object may produce a periodic cycle of bright glints when viewed from the ground. Alternatively, a spectrally distinct surface coating on the object may be detectable from the ground using a spectrometer. The design of Oculus-ASR uses specific shape properties as well as spectrally distinct materials on the spacecraft in order to emphasize, to the ground observer, changes in light intensity and spectral characteristics when viewed from the ground. Additionally, the nanosatellite has the ability to change its shape (and therefore its visible characteristics) while in orbit. It also possesses 3-axis control capability, allowing the Oculus-ASR to present different structural features and maneuver states to the ground observer. In order to accurately recognize the visible properties of the vehicle while in space, the nanosatellite has been optically characterized in an AFRL ground facility to determine reflective signatures that can be expected on orbit. Once on orbit, the Oculus-ASR will be monitored by ground-based telescopes and these observations will be reconciled against the ‘truth' attitude data recorded by the Oculus-ASR during various overpasses

  4. The Democratic Imperative to Address Sexual Equality Rights in Schools

    ERIC Educational Resources Information Center

    Gereluk, Dianne

    2013-01-01

    Issues of sexual orientation elicit ethical debates in schools and society. In jurisdictions where a legal right has not yet been established, one argument commonly rests on whether schools ought to address issues of same-sex relationships and marriage on the basis of civil equality, or whether such controversial issues ought to remain in the…

  5. Materials and design bases issues in ASME Code Case N-47

    SciTech Connect

    Huddleston, R.L.; Swindeman, R.W. )

    1993-04-01

    A preliminary evaluation of the design bases (principally ASME Code Case N-47) was conducted for design and operation of reactors at elevated temperatures where the time-dependent effects of creep, creep-fatigue, and creep ratcheting are significant. Areas where Code rules or regulatory guides may be lacking or inadequate to ensure the operation over the expected life cycles for the next-generation advanced high-temperature reactor systems, with designs to be certified by the US Nuclear Regulatory Commission, have been identified as unresolved issues. Twenty-two unresolved issues were identified and brief scoping plans developed for resolving these issues.

  6. Unresolved Loss, a Risk Factor for Offspring, Predicts Event-Related Potential Responses to Death-Related Imagery

    ERIC Educational Resources Information Center

    Bahm, Naomi I. Gribneau; Simon-Thomas, Emiliana R.; Main, Mary; Hesse, Erik

    2017-01-01

    This study investigates whether individual differences in attachment status can be detected by electrophysiological responses to loss-themed pictures. The Adult Attachment Interview (AAI) was used to identify discourse/reasoning lapses during the discussion of loss experiences via death that place speakers in the Unresolved/disorganized AAI…

  7. `Inverse Crime' and Model Integrity in Lightcurve Inversion applied to unresolved Space Object Identification

    NASA Astrophysics Data System (ADS)

    Henderson, Laura S.; Subbarao, Kamesh

    2016-12-01

    This work presents a case wherein the selection of models when producing synthetic light curves affects the estimation of the size of unresolved space objects. Through this case, "inverse crime" (using the same model for the generation of synthetic data and data inversion), is illustrated. This is done by using two models to produce the synthetic light curve and later invert it. It is shown here that the choice of model indeed affects the estimation of the shape/size parameters. When a higher fidelity model (henceforth the one that results in the smallest error residuals after the crime is committed) is used to both create, and invert the light curve model the estimates of the shape/size parameters are significantly better than those obtained when a lower fidelity model (in comparison) is implemented for the estimation. It is therefore of utmost importance to consider the choice of models when producing synthetic data, which later will be inverted, as the results might be misleadingly optimistic.

  8. Formation and Identification of Unresolved Complex Mixtures in Lacustrine Biodegraded Oil from Nanxiang Basin, China

    PubMed Central

    Guo, Pengfei; He, Sheng; Zhu, Shukui; Chai, Derong; Yin, Shiyan; Dai, Wei; Zhang, Wanfeng

    2014-01-01

    A comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC × GC/TOFMS) method has been developed for the formation and identification of unresolved complex mixtures (UCMs) in lacustrine biodegraded oils that with the same source rock, similar maturity, and increasing degradation rank from Nanxiang Basin, China. Normal alkanes, light hydrocarbons, isoprenoids, steranes, and terpanes are degraded gradually from oil B330 to oil G574. The compounds in biodegraded oil (oil G574) have fewer types, the polarity difference of compounds in different types is minor, and the relative content of individual compounds is similar. All the features make the compounds in biodegraded oil coelute in GC analysis and form the raised “baseline hump” named UCMs. By injecting standard materials and analyzing mass spectrums of target compounds, it is shown that cyclic alkanes with one to five rings are the major components of UCMs. Furthermore, UCMs were divided into six classes. Classes I and II, composed of alkyl-cyclohexanes, alkyl-naphthanes, and their isomers, are originated from the enrichment of hydrocarbons resistant to degradation in normal oils. Classes III ~ VI, composed of sesquiterpenoids, tricyclic terpanes, low molecular steranes, diasteranes, norhopanes, and their isomers, are probably from some newly formed compounds during the microbial transformation of oil. PMID:25177711

  9. Properties and Modeling of Unresolved Fine Structure Loops Observed in the Solar Transition Region by IRIS

    NASA Astrophysics Data System (ADS)

    Brooks, David H.; Reep, Jeffrey W.; Warren, Harry P.

    2016-08-01

    Recent observations from the Interface Region Imaging Spectrograph (IRIS) have discovered a new class of numerous low-lying dynamic loop structures, and it has been argued that they are the long-postulated unresolved fine structures (UFSs) that dominate the emission of the solar transition region. In this letter, we combine IRIS measurements of the properties of a sample of 108 UFSs (intensities, lengths, widths, lifetimes) with one-dimensional non-equilibrium ionization simulations, using the HYDRAD hydrodynamic model to examine whether the UFSs are now truly spatially resolved in the sense of being individual structures rather than being composed of multiple magnetic threads. We find that a simulation of an impulsively heated single strand can reproduce most of the observed properties, suggesting that the UFSs may be resolved, and the distribution of UFS widths implies that they are structured on a spatial scale of 133 km on average. Spatial scales of a few hundred kilometers appear to be typical for a range of chromospheric and coronal structures, and we conjecture that this could be an important clue for understanding the coronal heating process.

  10. Signatures of multiple stellar populations in unresolved extragalactic globular/young massive star clusters

    SciTech Connect

    Peacock, Mark B.; Zepf, Stephen E.; Finzell, Thomas

    2013-06-01

    We present an investigation of potential signatures of the formation of multiple stellar populations in recently formed extragalactic star clusters. All of the Galactic globular clusters for which good samples of individual stellar abundances are available show evidence for multiple populations. This appears to require that multiple episodes of star formation and light element enrichment are the norm in the history of a globular cluster. We show that there are detectable observational signatures of multiple formation events in the unresolved spectra of massive, young extragalactic star clusters. We present the results of a pilot program to search for one of the cleanest signatures that we identify—the combined presence of emission lines from a very recently formed population and absorption lines from a somewhat older population. A possible example of such a system is identified in the Antennae galaxies. This source's spectrum shows evidence of two stellar populations with ages of 8 Myr and 80 Myr. Further investigation shows that these populations are in fact physically separated, but only by a projected distance of 59 pc. We show that the clusters are consistent with being bound and discuss the possibility that their coalescence could result in a single globular cluster hosting multiple stellar populations. While not the prototypical system proposed by most theories of the formation of multiple populations in clusters, the detection of this system in a small sample is both encouraging and interesting. Our investigation suggests that expanded surveys of massive young star clusters should detect more clusters with such signatures.

  11. Exploring the temporal mechanism involved in the pitch of unresolved harmonics.

    PubMed

    Kaernbach, C; Bering, C

    2001-08-01

    This paper continues a line of research initiated by Kaernbach and Demany [J. Acoust. Soc. Am. 104, 2298-2306 (1998)], who employed filtered click sequences to explore the temporal mechanism involved in the pitch of unresolved harmonics. In a first experiment, the just noticeable difference (jnd) for the fundamental frequency (F0) of high-pass filtered and low-pass masked click trains was measured, with F0 (100 to 250 Hz) and the cut frequency (0.5 to 6 kHz) being varied orthogonally. The data confirm the result of Houtsma and Smurzynski [J. Acoust. Soc. Am. 87, 304-310 (1990)] that a pitch mechanism working on the temporal structure of the signal is responsible for analyzing frequencies higher than ten times the fundamental. Using high-pass filtered click trains, however, the jnd for the temporal analysis is at 1.2% as compared to 2%-3% found in studies using band-pass filtered stimuli. Two further experiments provide evidence that the pitch of this stimulus can convey musical information. A fourth experiment replicates the finding of Kaernbach and Demany on first- and second-order regularities with a cut frequency of 2 kHz and extends the paradigm to binaural aperiodic click sequences. The result suggests that listeners can detect first-order temporal regularities in monaural click streams as well as in binaurally fused click streams.

  12. Guyon Canal Syndrome: lack of management in a case of unresolved handlebar palsy

    PubMed Central

    Brown, Courtney K.; Stainsby, Brynne; Sovak, Guy

    2014-01-01

    Objective: To present the clinical diagnostic features including management of Guyon canal syndrome in a case with unresolved sensory deficits in a young female cyclist. Clinical Presentation: After 14 days of cycling across Canada, a 23-year old female experienced sensory loss, followed by atrophy and a “claw” hand appearance of her left hand. Intervention and Outcome: Treatment included cervical chiropractic manipulation, soft tissue therapy and the use of cycling gloves. Seven years after the initial injury a lack of sensation in the ulnar nerve distribution of her left hand has persisted. Discussion: This case demonstrates that a lack of proper management can lead to permanent sensory loss and is worth highlighting. Various therapists evaluated the patient’s symptoms and provided minimal care. No diagnosis was given, nor were appropriate measures taken for her to understand the risks of continuing to ride. Summary: Although treatment for Guyon Canal Syndrome can be as easy as cessation from cycling until symptoms subside, other treatment options could be utilized to help manage ulnar nerve compression injuries in cyclists. PMID:25550666

  13. 197Au(n,gamma) Cross Section in the Unresolved Resonance Region

    SciTech Connect

    Lederer, C.; Koehler, Paul Edward

    2011-03-01

    The cross section of the reaction {sup 197}Au(n,{gamma}) was measured with the time-of-flight technique at the n{_}TOF (neutron time-of-flight) facility in the unresolved resonance region between 5 and 400 keV using a pair of C{sub 6}D{sub 6} (where D denotes {sup 2}H) liquid scintillators for the detection of prompt capture {gamma} rays. The results with a total uncertainty of 3.9%-6.7% for a resolution of 20 bins per energy decade show fair agreement with the Evaluated Nuclear Data File Version B-VII.0 (ENDF/B-VII.0), which contains the standard evaluation. The Maxwellian-averaged cross section (MACS) at 30 keV is in excellent agreement with the one according to the ENDF/B-VII.0 evaluation and 4.7% higher than the MACS measured independently by activation technique. Structures in the cross section, which had also been reported earlier, have been interpreted as being due to clusters of resonances.

  14. Simultaneous quantitative analysis of isobars by tandem mass spectrometry from unresolved chromatographic peaks.

    PubMed

    Kushnir, Mark M; Rockwood, Alan L; Nelson, Gordon J

    2004-05-01

    A method was developed for the simultaneous quantitation of isobars from unresolved chromatographic peaks. The method is based on differences in branching ratios of ion abundances in their tandem mass spectra and an assumption that the product ion mass spectra of a mixture can be considered as a linear combination of the spectra of individual constituents. We present analytical equations and a matrix-based approach for deconvoluting the concentration of individual components from the total peak intensity for two and three isobars and also a matrix-based generalization to any number of compounds. The feasibility of the simultaneous analysis of mixtures containing two compounds was assessed. The approach was evaluated for the analysis of structural isomers of methylmalonic and succinic acids in human plasma and urine samples for a group of 270 samples. The linear regression equation, standard error and correlation coefficient for the agreement with a traditional method utilizing chromatographic separation of the isomers were y = 0.999x - 0.005, 0.024 micro mol l(-1), and 0.985, respectively. The utility of a spectral contrast angle as a predictor of analysis feasibility was evaluated.

  15. Au197(n,γ) cross section in the unresolved resonance region

    NASA Astrophysics Data System (ADS)

    Lederer, C.; Colonna, N.; Domingo-Pardo, C.; Gunsing, F.; Käppeler, F.; Massimi, C.; Mengoni, A.; Wallner, A.; Abbondanno, U.; Aerts, G.; Álvarez, H.; Álvarez-Velarde, F.; Andriamonje, S.; Andrzejewski, J.; Assimakopoulos, P.; Audouin, L.; Badurek, G.; Barbagallo, M.; Baumann, P.; Bečvář, F.; Belloni, F.; Berthoumieux, E.; Calviani, M.; Calviño, F.; Cano-Ott, D.; Capote, R.; Carrapiço, C.; Carrillo de Albornoz, A.; Cennini, P.; Chepel, V.; Chiaveri, E.; Cortes, G.; Couture, A.; Cox, J.; Dahlfors, M.; David, S.; Dillmann, I.; Dolfini, R.; Dridi, W.; Duran, I.; Eleftheriadis, C.; Embid-Segura, M.; Ferrant, L.; Ferrari, A.; Ferreira-Marques, R.; Fitzpatrick, L.; Frais-Koelbl, H.; Fujii, K.; Furman, W.; Goncalves, I.; González-Romero, E.; Goverdovski, A.; Gramegna, F.; Griesmayer, E.; Guerrero, C.; Haas, B.; Haight, R.; Heil, M.; Herrera-Martinez, A.; Igashira, M.; Isaev, S.; Jericha, E.; Kadi, Y.; Karadimos, D.; Karamanis, D.; Kerveno, M.; Ketlerov, V.; Koehler, P.; Konovalov, V.; Kossionides, E.; Krtička, M.; Lampoudis, C.; Leeb, H.; Lindote, A.; Lopes, I.; Losito, R.; Lozano, M.; Lukic, S.; Marganiec, J.; Marques, L.; Marrone, S.; Martínez, T.; Mastinu, P.; Mendoza, E.; Milazzo, P. M.; Moreau, C.; Mosconi, M.; Neves, F.; Oberhummer, H.; O'Brien, S.; Oshima, M.; Pancin, J.; Papachristodoulou, C.; Papadopoulos, C.; Paradela, C.; Patronis, N.; Pavlik, A.; Pavlopoulos, P.; Perrot, L.; Pigni, M. T.; Plag, R.; Plompen, A.; Plukis, A.; Poch, A.; Praena, J.; Pretel, C.; Quesada, J.; Rauscher, T.; Reifarth, R.; Rosetti, M.; Rubbia, C.; Rudolf, G.; Rullhusen, P.; Salgado, J.; Santos, C.; Sarchiapone, L.; Sarmento, R.; Savvidis, I.; Stephan, C.; Tagliente, G.; Tain, J. L.; Tarrío, D.; Tassan-Got, L.; Tavora, L.; Terlizzi, R.; Vannini, G.; Vaz, P.; Ventura, A.; Villamarin, D.; Vlachoudis, V.; Vlastou, R.; Voss, F.; Walter, S.; Wendler, H.; Wiescher, M.; Wisshak, K.

    2011-03-01

    The cross section of the reaction Au197(n,γ) was measured with the time-of-flight technique at the n_TOF (neutron time-of-flight) facility in the unresolved resonance region between 5 and 400 keV using a pair of C6D6 (where D denotes H2) liquid scintillators for the detection of prompt capture γ rays. The results with a total uncertainty of 3.9%-6.7% for a resolution of 20 bins per energy decade show fair agreement with the Evaluated Nuclear Data File Version B-VII.0 (ENDF/B-VII.0), which contains the standard evaluation. The Maxwellian-averaged cross section (MACS) at 30 keV is in excellent agreement with the one according to the ENDF/B-VII.0 evaluation and 4.7% higher than the MACS measured independently by activation technique. Structures in the cross section, which had also been reported earlier, have been interpreted as being due to clusters of resonances.

  16. Formation and identification of unresolved complex mixtures in lacustrine biodegraded oil from Nanxiang Basin, China.

    PubMed

    Guo, Pengfei; He, Sheng; Zhu, Shukui; Chai, Derong; Yin, Shiyan; Dai, Wei; Zhang, Wanfeng

    2014-01-01

    A comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC × GC/TOFMS) method has been developed for the formation and identification of unresolved complex mixtures (UCMs) in lacustrine biodegraded oils that with the same source rock, similar maturity, and increasing degradation rank from Nanxiang Basin, China. Normal alkanes, light hydrocarbons, isoprenoids, steranes, and terpanes are degraded gradually from oil B330 to oil G574. The compounds in biodegraded oil (oil G574) have fewer types, the polarity difference of compounds in different types is minor, and the relative content of individual compounds is similar. All the features make the compounds in biodegraded oil coelute in GC analysis and form the raised "baseline hump" named UCMs. By injecting standard materials and analyzing mass spectrums of target compounds, it is shown that cyclic alkanes with one to five rings are the major components of UCMs. Furthermore, UCMs were divided into six classes. Classes I and II, composed of alkyl-cyclohexanes, alkyl-naphthanes, and their isomers, are originated from the enrichment of hydrocarbons resistant to degradation in normal oils. Classes III ~ VI, composed of sesquiterpenoids, tricyclic terpanes, low molecular steranes, diasteranes, norhopanes, and their isomers, are probably from some newly formed compounds during the microbial transformation of oil.

  17. Modeling, estimation, and analysis of unresolved space object tracking and identification

    NASA Astrophysics Data System (ADS)

    Henderson, Laura Suarez

    The problem of orbit determination along with shape determination is significant. The orbit determination problem has been tackled for centuries by some of the greatest mathematicians and physicists. The issue of shape determination of space objects, although more recent, has also been addressed quite extensively. Nevertheless, these problems remain of great interest in the scientific and engineering community, and are addressed in this work. The greatest motivation for the tracking and identification of Earth orbiting objects is the ever-increasing population of space assets and man-made debris. It is of interest to implement new and better techniques to track and identify new debris and new orbiting bodies. The precise mathematical modeling of the space object's motion, along with the estimation of its position, velocity, attitude, angular velocity, shape, and size object is presented here. The first step is the development of mathematical model of the equations of motion of the orbiting body. The translational equations of motion are based on the orbiting two-body equations. In addition, rigid-body rotational equations are developed. This mathematical framework also includes models for perturbations. These perturbations are based on phenomena which affect the object as it orbits Earth. In order to acquire information regarding the object, astrometric and photometric measurement models are developed. These models emulate stations in the Space Surveillance Network. Special consideration is given to the development of the photometric model (i.e. the light curve model). The light curve measurement has only recently been used for this application and an extensive analysis of the information it carries is done. This study involves a sensitivity and observability analysis, which provide insight into the information contained in the light curve regarding the orientation, spin, shape, and size of the object. In addition, several mathematical models of the light

  18. Unresolved versus resolved: testing the validity of young simple stellar population models with VLT/MUSE observations of NGC 3603

    NASA Astrophysics Data System (ADS)

    Kuncarayakti, H.; Galbany, L.; Anderson, J. P.; Krühler, T.; Hamuy, M.

    2016-09-01

    Context. Stellar populations are the building blocks of galaxies, including the Milky Way. The majority, if not all, extragalactic studies are entangled with the use of stellar population models given the unresolved nature of their observation. Extragalactic systems contain multiple stellar populations with complex star formation histories. However, studies of these systems are mainly based upon the principles of simple stellar populations (SSP). Hence, it is critical to examine the validity of SSP models. Aims: This work aims to empirically test the validity of SSP models. This is done by comparing SSP models against observations of spatially resolved young stellar population in the determination of its physical properties, that is, age and metallicity. Methods: Integral field spectroscopy of a young stellar cluster in the Milky Way, NGC 3603, was used to study the properties of the cluster as both a resolved and unresolved stellar population. The unresolved stellar population was analysed using the Hα equivalent width as an age indicator and the ratio of strong emission lines to infer metallicity. In addition, spectral energy distribution (SED) fitting using STARLIGHT was used to infer these properties from the integrated spectrum. Independently, the resolved stellar population was analysed using the colour-magnitude diagram (CMD) to determine age and metallicity. As the SSP model represents the unresolved stellar population, the derived age and metallicity were tested to determine whether they agree with those derived from resolved stars. Results: The age and metallicity estimate of NGC 3603 derived from integrated spectroscopy are confirmed to be within the range of those derived from the CMD of the resolved stellar population, including other estimates found in the literature. The result from this pilot study supports the reliability of SSP models for studying unresolved young stellar populations. Based on observations collected at the European Organisation

  19. Constraining the redshifted 21-cm signal with the unresolved soft X-ray background

    NASA Astrophysics Data System (ADS)

    Fialkov, Anastasia; Cohen, Aviad; Barkana, Rennan; Silk, Joseph

    2017-01-01

    We use the observed unresolved cosmic X-ray background (CXRB) in the 0.5-2 keV band and existing upper limits on the 21-cm power spectrum to constrain the high-redshift population of X-ray sources, focusing on their effect on the thermal history of the Universe and the cosmic 21-cm signal. Because the properties of these sources are poorly constrained, we consider hot gas, X-ray binaries and mini-quasars (i.e. sources with soft or hard X-ray spectra) as possible candidates. We find that (1) the soft-band CXRB sets an upper limit on the X-ray efficiency of sources that existed before the end of reionization, which is one-to-two orders of magnitude higher than typically assumed efficiencies, (2) hard sources are more effective in generating the CXRB than the soft ones, (3) the commonly assumed limit of saturated heating is not valid during the first half of reionization in the case of hard sources, with any allowed value of X-ray efficiency, (4) the maximal allowed X-ray efficiency sets a lower limit on the depth of the absorption trough in the global 21-cm signal and an upper limit on the height of the emission peak, while in the 21-cm power spectrum it sets a minimum amplitude and frequency for the high-redshift peaks, and (5) the existing upper limit on the 21-cm power spectrum sets a lower limit on the X-ray efficiency for each model. When combined with the 21-cm global signal, the CXRB will be useful for breaking degeneracies and helping constrain the nature of high-redshift heating sources.

  20. THE SPITZER INFRARED SPECTROGRAPH DEBRIS DISK CATALOG. I. CONTINUUM ANALYSIS OF UNRESOLVED TARGETS

    SciTech Connect

    Chen, Christine H.; Mittal, Tushar; Kuchner, Marc; Forrest, William J.; Watson, Dan M.; Lisse, Carey M.; Manoj, P.; Sargent, Benjamin A.

    2014-04-01

    During the Spitzer Space Telescope cryogenic mission, Guaranteed Time Observers, Legacy Teams, and General Observers obtained Infrared Spectrograph (IRS) observations of hundreds of debris disk candidates. We calibrated the spectra of 571 candidates, including 64 new IRAS and Multiband Imaging Photometer for Spitzer (MIPS) debris disks candidates, modeled their stellar photospheres, and produced a catalog of excess spectra for unresolved debris disks. For 499 targets with IRS excess but without strong spectral features (and a subset of 420 targets with additional MIPS 70 μm observations), we modeled the IRS (and MIPS data) assuming that the dust thermal emission was well-described using either a one- or two-temperature blackbody model. We calculated the probability for each model and computed the average probability to select among models. We found that the spectral energy distributions for the majority of objects (∼66%) were better described using a two-temperature model with warm (T {sub gr} ∼ 100-500 K) and cold (T {sub gr} ∼ 50-150 K) dust populations analogous to zodiacal and Kuiper Belt dust, suggesting that planetary systems are common in debris disks and zodiacal dust is common around host stars with ages up to ∼1 Gyr. We found that younger stars generally have disks with larger fractional infrared luminosities and higher grain temperatures and that higher-mass stars have disks with higher grain temperatures. We show that the increasing distance of dust around debris disks is inconsistent with self-stirred disk models, expected if these systems possess planets at 30-150 AU. Finally, we illustrate how observations of debris disks may be used to constrain the radial dependence of material in the minimum mass solar nebula.

  1. Deriving the True Mass of an Unresolved Brown Dwarf Companion with AO Aided Astrometry

    NASA Astrophysics Data System (ADS)

    Meyer, Eva; Kürster, M.

    2010-01-01

    From radial velocity detections alone one does not get all orbital parameters needed to derive the true mass of a non-transiting, unresolved substellar companion to a star. Additional astrometric measurements are needed to calculate the inclination and the longitude of the ascending node. Until today only few true companion masses have been determined by this method with the HST fine guidance sensor (Benedict 2006, Benedict 2002). We aim to derive the true mass of a brown dwarf candidate companion to an early M 2.5V dwarf with groundbased high-resolution astrometry aided by adaptive optics. We found this unique brown dwarf desert object, which distance to the host star is only 0.42 AU, in our UVES precision radial velocity survey of M dwarfs, inferring a minimum companion mass of 27 Jupiter masses (Kuerster 2008). Combining the data with HIPPARCOS astrometry, we found a probability of only 2.9% that the companion is stellar. We are therefore observing the host star and a reference star within a monitoring program with VLT/NACO to derive the true mass of the companion and establish its nature (BD vs. star). Simultaneous observations of a reference field in a globular cluster are performed to determine the stability of the AO plus detector system and check its suitability for such high-precision astrometric measurements over several epochs which are needed to find and analyse extrasolar planet systems. We present preliminary results of the analysis of the astrometric displacements of the host star due to the unseen companion after correcting for differential refraction and differential aberration, as well as a first orbit fit and mass estimation.

  2. Unresolved Fine-scale Structure in Solar Coronal Loop-tops

    NASA Astrophysics Data System (ADS)

    Scullion, E.; Rouppe van der Voort, L.; Wedemeyer, S.; Antolin, P.

    2014-12-01

    New and advanced space-based observing facilities continue to lower the resolution limit and detect solar coronal loops in greater detail. We continue to discover even finer substructures within coronal loop cross-sections, in order to understand the nature of the solar corona. Here, we push this lower limit further to search for the finest coronal loop substructures, through taking advantage of the resolving power of the Swedish 1 m Solar Telescope/CRisp Imaging Spectro-Polarimeter (CRISP), together with co-observations from the Solar Dynamics Observatory/Atmospheric Image Assembly (AIA). High-resolution imaging of the chromospheric Hα 656.28 nm spectral line core and wings can, under certain circumstances, allow one to deduce the topology of the local magnetic environment of the solar atmosphere where its observed. Here, we study post-flare coronal loops, which become filled with evaporated chromosphere that rapidly condenses into chromospheric clumps of plasma (detectable in Hα) known as a coronal rain, to investigate their fine-scale structure. We identify, through analysis of three data sets, large-scale catastrophic cooling in coronal loop-tops and the existence of multi-thermal, multi-stranded substructures. Many cool strands even extend fully intact from loop-top to footpoint. We discover that coronal loop fine-scale strands can appear bunched with as many as eight parallel strands within an AIA coronal loop cross-section. The strand number density versus cross-sectional width distribution, as detected by CRISP within AIA-defined coronal loops, most likely peaks at well below 100 km, and currently, 69% of the substructure strands are statistically unresolved in AIA coronal loops.

  3. Unresolved fine-scale structure in solar coronal loop-tops

    SciTech Connect

    Scullion, E.; Van der Voort, L. Rouppe; Wedemeyer, S.; Antolin, P.

    2014-12-10

    New and advanced space-based observing facilities continue to lower the resolution limit and detect solar coronal loops in greater detail. We continue to discover even finer substructures within coronal loop cross-sections, in order to understand the nature of the solar corona. Here, we push this lower limit further to search for the finest coronal loop substructures, through taking advantage of the resolving power of the Swedish 1 m Solar Telescope/CRisp Imaging Spectro-Polarimeter (CRISP), together with co-observations from the Solar Dynamics Observatory/Atmospheric Image Assembly (AIA). High-resolution imaging of the chromospheric Hα 656.28 nm spectral line core and wings can, under certain circumstances, allow one to deduce the topology of the local magnetic environment of the solar atmosphere where its observed. Here, we study post-flare coronal loops, which become filled with evaporated chromosphere that rapidly condenses into chromospheric clumps of plasma (detectable in Hα) known as a coronal rain, to investigate their fine-scale structure. We identify, through analysis of three data sets, large-scale catastrophic cooling in coronal loop-tops and the existence of multi-thermal, multi-stranded substructures. Many cool strands even extend fully intact from loop-top to footpoint. We discover that coronal loop fine-scale strands can appear bunched with as many as eight parallel strands within an AIA coronal loop cross-section. The strand number density versus cross-sectional width distribution, as detected by CRISP within AIA-defined coronal loops, most likely peaks at well below 100 km, and currently, 69% of the substructure strands are statistically unresolved in AIA coronal loops.

  4. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions

    PubMed Central

    Estornes, Y; Aguileta, M A; Dubuisson, C; De Keyser, J; Goossens, V; Kersse, K; Samali, A; Vandenabeele, P; Bertrand, M J M

    2014-01-01

    Accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes ER stress and results in the activation of the unfolded protein response (UPR), which aims at restoring ER homeostasis. However, when the stress is too severe the UPR switches from being a pro-survival response to a pro-death one, and the molecular mechanisms underlying ER stress-mediated death have remained incompletely understood. In this study, we identified receptor interacting protein kinase 1 (RIPK1)—a kinase at the crossroad between life and death downstream of various receptors—as a new regulator of ER stress-induced death. We found that Ripk1-deficient MEFs are protected from apoptosis induced by ER stressors, which is reflected by reduced caspase activation and PARP processing. Interestingly, the pro-apoptotic role of Ripk1 is independent of its kinase activity, is not regulated by its cIAP1/2-mediated ubiquitylation, and does not rely on the direct regulation of JNK or CHOP, two reportedly main players in ER stress-induced death. Instead, we found that ER stress-induced apoptosis in these cells relies on death receptor-independent activation of caspase-8, and identified Ripk1 upstream of caspase-8. However, in contrast to RIPK1-dependent apoptosis downstream of TNFR1, we did not find Ripk1 associated with caspase-8 in a death-inducing complex upon unresolved ER stress. Our data rather suggest that RIPK1 indirectly regulates caspase-8 activation, in part via interaction with the ER stress sensor inositol-requiring protein 1 (IRE1). PMID:25476903

  5. The Reach Address Database (RAD)

    EPA Pesticide Factsheets

    The Reach Address Database (RAD) stores reach address information for each Water Program feature that has been linked to the underlying surface water features (streams, lakes, etc) in the National Hydrology Database (NHD) Plus dataset.

  6. State of the Union Address, 1997. Remarks by the President in State of the Union Address.

    ERIC Educational Resources Information Center

    Executive Office of the President, Washington, DC.

    This document contains the text of President Clinton's State of the Union Address, delivered on February 4, 1997. The President issues a call to action to work together to prepare America for the twenty-first century. The United States must attend to the unfinished business of balancing the budget, enacting bipartisan campaign-finance reform, and…

  7. ADDRESSING ENVIRONMENTAL ENGINEERING CHALLENGES WITH COMPUTATIONAL FLUID DYNAMICS

    EPA Science Inventory

    In the field of environmental engineering, modeling tools are playing an ever larger role in addressing air quality issues, including source pollutant emissions, atmospheric dispersion and human exposure risks. More detailed modeling of environmental flows requires tools for c...

  8. Transition. Feature Issue.

    ERIC Educational Resources Information Center

    Wallace, Teri, Ed.; And Others

    1992-01-01

    This feature issue of a quarterly bulletin on community integration addresses the topic of transition services for preparing youth with disabilities for adult community living. It contains articles with the following titles and authors: "Transition: The Next Five Years" (David R. Johnson and others); "Transition Policy in the 1990s:…

  9. Special Book Review Issue.

    ERIC Educational Resources Information Center

    Grauer, Barbara Ellman, Ed.; And Others

    1998-01-01

    Provides reviews of books dealing with all aspects of careers, including 8 books on dealing with change, 13 on career management, 4 on entrepreneurship, 3 guides and workbooks, 2 on assessment, 4 on resumes, and 1 biography. Includes 12 short reviews of books on career development issues and information such as publishers' addresses. (JOW)

  10. Effects of unresolved satellite lines on lasing of extreme ultraviolet light with nitrogen plasma in a recombining phase

    NASA Astrophysics Data System (ADS)

    Tatsumura, Nao; Yamamura, Shuhei; Ozawa, Takuya; Horioka, Kazuhiko; Kawamura, Tohru

    2013-08-01

    Satellite lines with a high-lying spectator electron give unresolved spectral feature with respect to a parent resonance line. In our previous study [T. Ozawa et al., Phys. Plasmas 19, 063302 (2012)], population inversion between 3l and 2l of hydrogenlike nitrogen in a recombining phase was quantitatively estimated and the dielectronic-capture ladderlike processes, which implicitly include such doubly excited states as nln 'l' (n=2-4,n'≫n), were found to be indispensable in the estimation of a gain. In this study, the population densities of the doubly excited states are explicitly calculated by a time-dependent collisional-radiative model with desired plasma conditions for the lasing of nitrogen Balmer-α, which is a parent resonance line of unresolved satellite lines 3ln'l'→2ln'l'. The stimulated emission of the unresolved satellite lines caused by Balmer-α is found to reduce the population inversion between 3l and 2l, leading to essential saturation of the amplification of Balmer-α laser light.

  11. Distribution of unresolvable anisotropic microstructures revealed in visibility-contrast images using x-ray Talbot interferometry

    SciTech Connect

    Yashiro, Wataru; Harasse, Sebastien; Kawabata, Katsuyuki; Kuwabara, Hiroaki; Yamazaki, Takashi; Momose, Atsushi

    2011-09-01

    X-ray Talbot interferometry has been widely used as a technique for x-ray phase imaging and tomography. We propose a method using this interferometry for mapping distribution of parameters characterizing anisotropic microstructures, which are typically of the order of {mu}m in size and cannot be resolved by the imaging system, in a sample. The method uses reduction in fringe visibility, which is caused by such unresolvable microstructures, in moire images obtained using an interferometer. We applied the method to a chloroprene rubber sponge sample, which exhibited uniaxial anisotropy of reduced visibility. We measured the dependencies of reduced visibility on both the Talbot order and the orientation of the sample and obtained maps of three parameters and their anisotropies that characterize the unresolvable anisotropic microstructures in the sample. The maps indicated that the anisotropy of the sample's visibility contrast mainly originated from the anisotropy of the microstructure elements' average size. Our method directly provides structural information on unresolvable microstructures in real space, which is only accessible through the ultra-small-angle x-ray scattering measurements in reciprocal space, and is expected to be broadly applied to material, biological, and medical sciences.

  12. Special Issue of Teaching Ideas.

    ERIC Educational Resources Information Center

    Health Education (Washington D.C.), 1986

    1986-01-01

    This special issue contains teaching strategies and suggestions for health-related activities at all educational levels. A few of the topics addressed by the 21 articles are heart disease, testicular cancer, hospital stress, family life, and sexual responsibility. (MT)

  13. Contractual Issues for Faculty Practice.

    ERIC Educational Resources Information Center

    Williams, M. Dee; Gregg, Andrea C.

    2001-01-01

    Discusses contractual issues surrounding nursing faculty's clinical practice, such as competent participants, offer, consideration, and acceptance. Addresses evaluation of faculty practice contracts and alternatives for problem resolution. (Contains 24 references.) (SK)

  14. Nutrition interventions to address cardiovascular outcomes in chronic kidney disease.

    PubMed

    Beto, Judith A; Bansal, Vinod K

    2004-10-01

    The high mortality in chronic kidney disease has been linked to cardiovascular risk and these patients are considered at high risk. Dietary intervention can directly address nutritional risk factors in lipid management, calcium-phorphorus balance, and body composition to reduce risk of cardiovascular disease. Nutrient intake can also indirectly address less overt risks of dental health, nutritional supplements, and compliance issues.

  15. Addressing Barriers to Learning. Volume 11, Number 2. Spring 2006

    ERIC Educational Resources Information Center

    Center for Mental Health in Schools at UCLA, 2006

    2006-01-01

    This issue of the quarterly newsletter of the Center for Mental Health in Schools includes the following features and regular segments: (1) Concerns = Opportunities: Addressing Student Disengagement, Acting Out, and Dropouts by Moving in New Directions; (2) Info Sheet: Costs of Not Addressing Barriers to Learning; and (3) Current Status of Mental…

  16. Genetic Issues in Mental Retardation, 1996-1997.

    ERIC Educational Resources Information Center

    Genetic Issues in Mental Retardation, 1996

    1996-01-01

    This document consists of the first six issues of a newsletter, which discusses current knowledge about and concerns related to genetics and mental retardation. The second issue addresses the problem of genetic discrimination. The third issue considers genetic testing, screening, and counseling. The fourth issue addresses genetic privacy issues.…

  17. CONTENT-ADDRESSABLE MEMORY SYSTEMS,

    DTIC Science & Technology

    The utility of content -addressable memories (CAM’s) within a general purpose computing system is investigated. Word cells within CAM may be...addressed by the character of all or a part of cell contents . Multimembered sets of word cells may be addressed simultaneously. The distributed logical...package is developed which allows simulation of CAM commands within job programs run on the IBM 7090 and derives tallies of execution times corresponding to a particular realization of a CAM system . (Author)

  18. Addressing Stereotypes by Moving along the Continuum of Cultural Proficiency

    ERIC Educational Resources Information Center

    Ward, Cheryl James

    2013-01-01

    Programs to help middle school students deal with racism and hate have been in place for some years, yet almost monthly we hear of students committing suicide or killing other students due to issues of isolation or harassment. Within the confines of a safe classroom, doctoral students in Educational Leadership addressed issues of stereotypes and…

  19. Innovative Legal Approaches to Address Obesity

    PubMed Central

    Pomeranz, Jennifer L; Teret, Stephen P; Sugarman, Stephen D; Rutkow, Lainie; Brownell, Kelly D

    2009-01-01

    Context: The law is a powerful public health tool with considerable potential to address the obesity issue. Scientific advances, gaps in the current regulatory environment, and new ways of conceptualizing rights and responsibilities offer a foundation for legal innovation. Methods: This article connects developments in public health and nutrition with legal advances to define promising avenues for preventing obesity through the application of the law. Findings: Two sets of approaches are defined: (1) direct application of the law to factors known to contribute to obesity and (2) original and innovative legal solutions that address the weak regulatory stance of government and the ineffectiveness of existing policies used to control obesity. Specific legal strategies are discussed for limiting children's food marketing, confronting the potential addictive properties of food, compelling industry speech, increasing government speech, regulating conduct, using tort litigation, applying nuisance law as a litigation strategy, and considering performance-based regulation as an alternative to typical regulatory actions. Finally, preemption is an overriding issue and can play both a facilitative and a hindering role in obesity policy. Conclusions: Legal solutions are immediately available to the government to address obesity and should be considered at the federal, state, and local levels. New and innovative legal solutions represent opportunities to take the law in creative directions and to link legal, nutrition, and public health communities in constructive ways. PMID:19298420

  20. Issues in Numerical Simulation of Fire Suppression

    SciTech Connect

    Tieszen, S.R.; Lopez, A.R.

    1999-04-12

    This paper outlines general physical and computational issues associated with performing numerical simulation of fire suppression. Fire suppression encompasses a broad range of chemistry and physics over a large range of time and length scales. The authors discuss the dominant physical/chemical processes important to fire suppression that must be captured by a fire suppression model to be of engineering usefulness. First-principles solutions are not possible due to computational limitations, even with the new generation of tera-flop computers. A basic strategy combining computational fluid dynamics (CFD) simulation techniques with sub-grid model approximations for processes that have length scales unresolvable by gridding is presented.

  1. Addressing Medical Errors in Hand Surgery

    PubMed Central

    Johnson, Shepard P.; Adkinson, Joshua M.; Chung, Kevin C.

    2014-01-01

    Influential think-tank such as the Institute of Medicine has raised awareness about the implications of medical errors. In response, organizations, medical societies, and institutions have initiated programs to decrease the incidence and effects of these errors. Surgeons deal with the direct implications of adverse events involving patients. In addition to managing the physical consequences, they are confronted with ethical and social issues when caring for a harmed patient. Although there is considerable effort to implement system-wide changes, there is little guidance for hand surgeons on how to address medical errors. Admitting an error is difficult, but a transparent environment where patients are notified of errors and offered consolation and compensation is essential to maintain trust. Further, equipping hand surgeons with a guide for addressing medical errors will promote compassionate patient interaction, help identify system failures, provide learning points for safety improvement, and demonstrate a commitment to ethically responsible medical care. PMID:25154576

  2. Computer Technology and Social Issues.

    ERIC Educational Resources Information Center

    Garson, G. David

    Computing involves social issues and political choices. Issues such as privacy, computer crime, gender inequity, disemployment, and electronic democracy versus "Big Brother" are addressed in the context of efforts to develop a national public policy for information technology. A broad range of research and case studies are examined in an…

  3. Ethnic Studies: Issues and Approaches.

    ERIC Educational Resources Information Center

    Yang, Philip Q.

    This book offers a comprehensive definition of the field of ethnic studies, covering both major issues in the field and its theoretical and methodological approaches. It traces the origins and evolution of the discipline in the United States and maps its domain. Some of the current issues addressed include affirmative action, illegal/legal…

  4. Drugs. Social Issues Resources Series.

    ERIC Educational Resources Information Center

    Goldstein, Eleanor C.; And Others

    The Social Issues Resources Series (SIRS) is a set of loose leaf units each of which is addressed to a different social issue. Each unit consists of articles which have been reproduced from newspapers, magazines, journals and government publications representing the prevailing spectrum of opinion, emphasis and complexity. Sixty articles are…

  5. Issues Curriculum.

    ERIC Educational Resources Information Center

    Sando, Joe S.

    A program for teaching techniques of critical thinking on issues concerning American Indians was developed for students at Albuquerque Indian School. It was designed to include not only the students but also their families with learning activities that required consultation in search of answers or understanding. The first issue presented sought to…

  6. A SUB-GRID VOLUME-OF-FLUIDS (VOF) MODEL FOR MIXING IN RESOLVED SCALE AND IN UNRESOLVED SCALE COMPUTATIONS

    SciTech Connect

    VOLD, ERIK L.; SCANNAPIECO, TONY J.

    2007-10-16

    A sub-grid mix model based on a volume-of-fluids (VOF) representation is described for computational simulations of the transient mixing between reactive fluids, in which the atomically mixed components enter into the reactivity. The multi-fluid model allows each fluid species to have independent values for density, energy, pressure and temperature, as well as independent velocities and volume fractions. Fluid volume fractions are further divided into mix components to represent their 'mixedness' for more accurate prediction of reactivity. Time dependent conversion from unmixed volume fractions (denoted cf) to atomically mixed (af) fluids by diffusive processes is represented in resolved scale simulations with the volume fractions (cf, af mix). In unresolved scale simulations, the transition to atomically mixed materials begins with a conversion from unmixed material to a sub-grid volume fraction (pf). This fraction represents the unresolved small scales in the fluids, heterogeneously mixed by turbulent or multi-phase mixing processes, and this fraction then proceeds in a second step to the atomically mixed fraction by diffusion (cf, pf, af mix). Species velocities are evaluated with a species drift flux, {rho}{sub i}u{sub di} = {rho}{sub i}(u{sub i}-u), used to describe the fluid mixing sources in several closure options. A simple example of mixing fluids during 'interfacial deceleration mixing with a small amount of diffusion illustrates the generation of atomically mixed fluids in two cases, for resolved scale simulations and for unresolved scale simulations. Application to reactive mixing, including Inertial Confinement Fusion (ICF), is planned for future work.

  7. Addressing the underperformance of faculty and staff.

    PubMed

    Kenner, Carole; Pressler, Jana L

    2006-01-01

    Many new nursing leaders assuming work as deans, assistant deans, or interim deans have limited education, experience, or background to prepare them for the job. To assist new deans and those aspiring to be deans, the authors of this department, both deans, offer survival tips based on their personal experiences and insights. They address common issues, challenges, and opportunities that face academic executive teams, such as negotiating an executive contract, obtaining faculty lines, building effective work teams, managing difficult employees, and creating nimble organizational structure to respond to changing consumer, healthcare delivery, and community needs. The authors welcome counterpoint discussions with readers.

  8. Temporal behavior of unresolved transition array emission in water window soft x-ray spectral region from multiply charged ions

    NASA Astrophysics Data System (ADS)

    Dinh, Thanh-Hung; Suzuki, Yuhei; Arai, Goki; Li, Bowen; Dunne, Padraig; O'Sullivan, Gerry; Fujioka, Shinsuke; Hasegawa, Noboru; Kawachi, Tetsuya; Nishikino, Masaharu; Higashiguchi, Takeshi

    2015-09-01

    We have characterized the spectral structure and the temporal history of the laser-produced high-Z multi-charged ion plasmas for the efficient water window soft x-ray sources. Strong unresolved transition array emission was observed due to 4d-4f and 4f-5g transitions from Au, Pb, and Bi plasmas in the 280-700 eV photon energy region. The temporal behavior of the emission was essentially similar of that of the laser pulse with a slight delay between different transitions. These results provide feedback for accurate modeling of the atomic processes with the radiative hydrodynamic simulations.

  9. A Structurally Unresolved Head Segment of Defined Length Favors Proper Measles Virus Hemagglutinin Tetramerization and Efficient Membrane Fusion Triggering

    PubMed Central

    Navaratnarajah, Chanakha K.; Rosemarie, Quincy

    2015-01-01

    ABSTRACT Paramyxoviruses include several insidious and ubiquitous pathogens of humans and animals, with measles virus (MeV) being a prominent one. The MeV membrane fusion apparatus consists of a receptor binding protein (hemagglutinin [H]) tetramer and a fusion (F) protein trimer. Four globular MeV H heads are connected to a tetrameric stalk through flexible linkers. We sought here to characterize the function of a 17-residue H-head segment proximal to the stalk that was unresolved in all five MeV H-head crystal or cocrystal structures. In particular, we assessed whether its primary sequence and length are critical for proper protein oligomerization and intracellular transport or for membrane fusion triggering. Extensive alanine substitutions had no effect on fusion triggering, suggesting that sequence identity is not critical for this function. Excessive shortening of this segment reduced or completely abrogated fusion trigger function, while length compensation restored it. We then characterized the mechanism of function loss. Mutated H proteins were efficiently transported to the cell surface, but certain alterations enhancing linker flexibility resulted in accumulation of high-molecular-weight H oligomers. Some oligomers had reduced fusion trigger capacity, while others retained this function. Thus, length and rigidity of the unresolved head segment favor proper H tetramerization and counteract interactions between subunits from different tetramers. The structurally unresolved H-head segment, together with the top of the stalk, may act as a leash to provide the right degree of freedom for the heads of individual tetramers to adopt a triggering-permissive conformation while avoiding improper contacts with heads of neighboring tetramers. IMPORTANCE Understanding the molecular mechanism of membrane fusion triggering may allow development of new antiviral strategies. The fusion apparatus of paramyxoviruses consists of a receptor binding tetramer and a fusion

  10. Special issue: Volcanic geology of the Azores Islands

    USGS Publications Warehouse

    Nunes, João Carlos; Tilling, Robert I.; Sigvaldason, Gudmundur E.

    2006-01-01

    and location of the “Azores hot spot”? Is it fixed or moving?By way of background, with the aim of addressing at least the volcanological aspects of these unresolved scientific questions, a “Pico Island International Volcanological Meeting” has been convened three times in recent years (2001, 2002, and 2004). We originally were invited by Elsevier to produce a Special Issue of JVGR focusing on the main conclusions of the papers to be presented at 2002 Pico meeting. However, at the time, we believed that it would be more appropriate to have a Special Issue that would be broader in scope than the meeting itself and involve a greater number of potential contributors, by inviting all researchers in Portugal and abroad who have conducted geoscience studies in the Azores. Thus, this Special Issue contains contributions of those researchers who accepted our invitation to share with the global volcanologic community the findings and insights from their investigations of the Azores Islands and surrounding seafloor. The collection of papers in this Special Issue constitutes a representative sampling of the wide-ranging research conducted on the Azores Archipelago, on land and offshore. This sampling encompasses a variety of geological, geophysical, tomographical, petrologic–geochemical, geothermal studies, as well as assessments of natural hazards.

  11. Proceedings of the Hydrokinetic and Wave Energy Technologies Technical and Environmental Issues Workshop

    SciTech Connect

    2006-03-01

    Renewable energy technologies offer the promise of non-polluting alternatives to fossil and nuclear-fueled power plants to meet growing demand for electrical energy. Two emerging categories of renewable energy technologies, hydrokinetic and wave energy conversion devices, offer ways to tap the energy of moving water without impoundment (dams) or diversion required by many conventional hydroelectric facilities. These technologies include devices designed for deployment in natural streams, tidal estuaries, ocean currents, and constructed waterways, as well as devices designed to capture the energy of ocean waves. On October 26-28, 2005, 54 representatives from government, non-governmental organizations, and private business met to (1) identify the varieties of hydrokinetic energy and wave technology devices, their stages of development, and the projected cost to bring each to market; (2) identify where these technologies can best operate; (3) identify the potential environmental issues associated with these technologies and possible mitigation measures; (4) develop a list of research needs and/or practical solutions to address unresolved environmental issues. These workshop proceedings include detailed summaries of the 24 presentations made and the discussions that followed.

  12. KrF amplifier design issues and application to ICF system design

    SciTech Connect

    Sullivan, J.A.; Allen, G.R.; Berggren, R.R.; Czuchlewski, S.J.; Harris, D.B.; Jones, M.E.; Krohn, B.J.; Kurnit, N.A.; Leland, W.T.; Mansfield, C.; McLeod, J.; McCown, A.W.; McLeod, J.; Pendergrass, J.H.; Rose, E.A.; Rosocha, L.A.; Thomas, V.A.

    1991-01-01

    Los Alamos National Laboratory has assembled an array of experimental and theoretical tools to optimize amplifier design for future KrF lasers. The next opportunity to exercise these tools is with the design of the second generation NIKE system under construction at the Naval Research Laboratory with the collaboration of Los Alamos National Laboratory. Major issues include laser physics (energy extraction in large modules with amplified spontaneous emission) and diode performance and efficiency. High efficiency and low cost are increasingly important for larger future KrF amplifiers. In this paper we present our approach to amplifier scaling and discuss the more important design considerations for large KrF amplifiers. We point out where improvements in the fundamental data base for KrF amplifiers could lead to increased confidence in performance predictions for large amplifiers, and we address the currently unresolved issues of anomalous absorption near line center and the possibility of diode instabilities for low impedance designs. Los Alamos has designed a 100-kJ KrF laser-fusion system for both direct- and indirect-drive target physics experiments using 60-kJ amplifier modules. The design of this system will be reviewed. 38 refs., 110 figs., 3 tabs.

  13. Issues management made easier

    SciTech Connect

    Brownson, L.

    1993-10-01

    Increases in ES&H compliance issues within the past few years have necessitated a formal process by which DOE facilities address these issues. In May 1991, ANL-W implemented the ANL-W Issues Management System (IMS) to facilitate the management of compliance issues and scheduling of corrective action plans with limited resources. The central focus of this process is a computer database, Integrated Resource Management System (IRMS), which allows quick retrieval of compliance information, organization of compliance issues based on a risk-based prioritization methodology, and tracking of corrective action plans. Without the IRMS, the ANL-W Issues Management System would have been difficult to administer and manage. ANL-W has used the IRMS for both audit preparation and audit response, most noticeably the preparation and subsequent response to the 1991 Tiger Team audit. The IRMS was used to track ANL-W Self-Assessment corrective action plans, provide instant information to Tiger Team members regarding Self-Assessment findings, produce prioritized lists of Tiger Team concerns for developing corrective action plans, and track Tiger Team corrective action plans. Status reports to senior, laboratory management regarding the Tiger Team corrective action plan are produced based on information provided by the IRMS. This paper discusses the criteria used for selecting the IRMS, implementation of the Issues Management System using the IRMS, lessons learned, and the future evolution of the IRMS.

  14. Contractual issues for faculty practice.

    PubMed

    Gregg, A C; Williams, M D

    2001-01-01

    Contracts are a common foundation for faculty practice relationships between a college of nursing and other agencies. Although the legal format of a contract is relatively standardized, the process of contracting entails decisions and issues that increase its complexity. Little is available in the faculty practice literature that addresses contracts and contractual issues as a comprehensive whole. This article contains discussions of nursing faculty practice contractual issues such as the elements of a contract as a framework, including competent parties, offer, consideration, and acceptance. Evaluation of contract performance is addressed and alternatives for decision making and problem resolutions are suggested throughout. J Prof Nurs 17:173-179, 2001.

  15. Pipetron Tunnel Construction Issues

    SciTech Connect

    Friant, James E.; Bauer, Robert A.; Gross, David L.; May, Michael; Lach, Joseph

    1997-01-01

    This report examines issues involved in the civil construction aspects of the tunneling that could be done in the region of Fermilab to support the Pipetron along, moderately deep, tunnel loop. Cost, technical and political aspects of tunneling are addressed in this preliminary guide for further study. At Snowmass 96, in a series of informal, but comprehensive discussions, several guidelines were developed to frame this report.

  16. A web-based troubleshooting tool to help customers self-solve color issues with a digital printing workflow

    NASA Astrophysics Data System (ADS)

    Santos-Villalobos, Hector J.; Loewen, Victor; Lehto, Mark; Allebach, Jan

    2011-03-01

    Current printing technologies enable customers to reproduce high quality, realistic, and colorful hard copies of their digital documents. Although the activity of printing is transparent to the customers, the progression of a customer's document through the color printing workflow (CPW) is a complex process that may alter the colors in the print job. Given the complexity of the CPW, it is a difficult problem to diagnose the source of the color issue. Novel tools and methods that address this challenge are beneficial for both the manufacturer and its customers. We propose a Web-based troubleshooting tool that helps customers to self-solve color issues with electrophotographic laser printers when printing solid colors in graphics and text. The tool helps the customer to reconfigure his/her CPW following printing best practices. If the issue is still unresolved, the tool guides the user to search the gamut of the printer for his/her color preference. The usability of the tool was carefully evaluated with human subject experiments. Also, the description and organization of the troubleshooting tasks were continuously reviewed and improved in regular meetings of the development team. In this paper, we describe the troubleshooting strategy, the color preference search algorithm, and the results of the usability experiments.

  17. UNRESOLVED MIXED POLARITY MAGNETIC FIELDS AT FLUX CANCELLATION SITE IN SOLAR PHOTOSPHERE AT 0.''3 SPATIAL RESOLUTION

    SciTech Connect

    Kubo, Masahito; Low, Boon Chye; Lites, Bruce W

    2014-09-20

    This is a follow-up investigation of a magnetic flux cancellation event at a polarity inversion line (PIL) on the Sun observed with the spectropolarimeter on board Hinode. Anomalous circular polarization (Stokes V) profiles are observed in the photosphere along the PIL at the cancellation sites. Kubo et al. previously reported that the theoretically expected horizontal fields between the canceling opposite-polarity magnetic elements in this event are not detected at granular scales. We show that the observed anomalous Stokes V profiles are reproduced successfully by adding the nearly symmetric Stokes V profiles observed at pixels immediately adjacent to the PIL. This result suggests that these observed anomalous Stokes V profiles are not indications of a flux removal process, but are the result of either a mixture of unresolved, opposite-polarity magnetic elements or the unresolved width of the PIL, at an estimated resolution element of about 0.''3. The hitherto undetected flux removal process accounting for the larger-scale disappearance of magnetic flux during the observing period is likely to also fall below resolution.

  18. Results from an experiment that collected visible-light polarization data using unresolved imagery for classification of geosynchronous satellites

    NASA Astrophysics Data System (ADS)

    Speicher, Andy; Matin, Mohammad; Tippets, Roger; Chun, Francis; Strong, David

    2015-05-01

    In order to protect critical military and commercial space assets, the United States Space Surveillance Network must have the ability to positively identify and characterize all space objects. Unfortunately, positive identification and characterization of space objects is a manual and labor intensive process today since even large telescopes cannot provide resolved images of most space objects. The objective of this study was to collect and analyze visible-spectrum polarization data from unresolved images of geosynchronous satellites taken over various solar phase angles. Different collection geometries were used to evaluate the polarization contribution of solar arrays, thermal control materials, antennas, and the satellite bus as the solar phase angle changed. Since materials on space objects age due to the space environment, their polarization signature may change enough to allow discrimination of identical satellites launched at different times. Preliminary data suggests this optical signature may lead to positive identification or classification of each satellite by an automated process on a shorter timeline. The instrumentation used in this experiment was a United States Air Force Academy (USAFA) Department of Physics system that consists of a 20-inch Ritchey-Chrétien telescope and a dual focal plane optical train fed with a polarizing beam splitter. Following a rigorous calibration, polarization data was collected during two nights on eight geosynchronous satellites built by various manufacturers and launched several years apart. When Stokes parameters were plotted against time and solar phase angle, the data indicates that a polarization signature from unresolved images may have promise in classifying specific satellites.

  19. A high-significance measurement of correlation between unresolved IRAS sources and optically-selected galaxy clusters

    SciTech Connect

    Hincks, Adam D.; Hajian, Amir; Addison, Graeme E. E-mail: ahajian@cita.utoronto.ca

    2013-05-01

    We cross-correlate the 100 μm Improved Reprocessing of the IRAS Survey (IRIS) map and galaxy clusters at 0.1 < z < 0.3 in the maxBCG catalogue taken from the Sloan Digital Sky Survey, measuring an angular cross-power spectrum over multipole moments 150 < l < 3000 at a total significance of over 40σ. The cross-spectrum, which arises from the spatial correlation between unresolved dusty galaxies that make up the cosmic infrared background (CIB) in the IRIS map and the galaxy clusters, is well-fit by a single power law with an index of −1.28±0.12, similar to the clustering of unresolved galaxies from cross-correlating far-infrared and submillimetre maps at longer wavelengths. Using a recent, phenomenological model for the spectral and clustering properties of the IRIS galaxies, we constrain the large-scale bias of the maxBCG clusters to be 2.6±1.4, consistent with existing analyses of the real-space cluster correlation function. The success of our method suggests that future CIB-optical cross-correlations using Planck and Herschel data will significantly improve our understanding of the clustering and redshift distribution of the faint CIB sources.

  20. Addressing language barriers to healthcare in India.

    PubMed

    Narayan, Lalit

    2013-01-01

    In spite of a growing recognition of the importance of doctor-patient communication, the issue of language barriers to healthcare has received very little attention in India. The Indian population speaks over 22 major languages with English used as the lingua franca for biomedicine. Large-scale internal migration has meant that health workers are encountering increasing instances of language discordance within clinical settings. Research done predominantly in the West has shown language discordance to significantly affect access to care, cause problems of comprehension and adherence, and decrease the satisfaction and quality of care. Addressing language barriers to healthcare in India requires a stronger political commitment to providing non-discriminatory health services, especially to vulnerable groups such as illiterate migrant workers. Research will have to address three broad areas: the ways in which language barriers affect health and healthcare, the efficacy of interventions to overcome language barriers, and the costs of language barriers and efforts to overcome them. There is a need to address such barriers in health worker education and clinical practice. Proven strategies such as hiring multilingual healthcare workers, providing language training to health providers, employing in situ translators or using telephone interpretation services will have to be evaluated for their appropriateness to the Indian context. Internet-based initiatives, the proliferation of mobile phones and recent advances in machine translation promise to contribute to the solution.

  1. Every Other Day. Keynote Address.

    ERIC Educational Resources Information Center

    Tiller, Tom

    Schools need to be reoriented and restructured so that what is taught and learned, and the way in which it is taught and learned, are better integrated with young people's real-world experiences. Many indicators suggest that the meaningful aspects of school have been lost in the encounter with modern times. The title of this address--"Every…

  2. Agenda to address climate change

    SciTech Connect

    1998-10-01

    This document looks at addressing climate change in the 21st century. Topics covered are: Responding to climate change; exploring new avenues in energy efficiency; energy efficiency and alternative energy; residential sector; commercial sector; industrial sector; transportation sector; communities; renewable energy; understanding forests to mitigate and adapt to climate change; the Forest Carbon budget; mitigation and adaptation.

  3. Keynote Address: Rev. Mark Massa

    ERIC Educational Resources Information Center

    Massa, Mark S.

    2011-01-01

    Rev. Mark S. Massa, S.J., is the dean and professor of Church history at the School of Theology and Ministry at Boston College. He was invited to give a keynote to begin the third Catholic Higher Education Collaborative Conference (CHEC), cosponsored by Boston College and Fordham University. Fr. Massa's address posed critical questions about…

  4. State of the Lab Address

    ScienceCinema

    King, Alex

    2016-07-12

    In his third-annual State of the Lab address, Ames Laboratory Director Alex King called the past year one of "quiet but strong progress" and called for Ames Laboratory to continue to build on its strengths while responding to changing expectations for energy research.

  5. Research strategies for addressing uncertainties

    USGS Publications Warehouse

    Busch, David E.; Brekke, Levi D.; Averyt, Kristen; Jardine, Angela; Welling, Leigh; Garfin, Gregg; Jardine, Angela; Merideth, Robert; Black, Mary; LeRoy, Sarah

    2013-01-01

    Research Strategies for Addressing Uncertainties builds on descriptions of research needs presented elsewhere in the book; describes current research efforts and the challenges and opportunities to reduce the uncertainties of climate change; explores ways to improve the understanding of changes in climate and hydrology; and emphasizes the use of research to inform decision making.

  6. The emergence of sarcoptic mange in Australian wildlife: an unresolved debate.

    PubMed

    Fraser, Tamieka A; Charleston, Michael; Martin, Alynn; Polkinghorne, Adam; Carver, Scott

    2016-06-02

    Due to its suspected increase in host range and subsequent global diversification, Sarcoptes scabiei has important implications at a global scale for wildlife conservation and animal and human health. The introduction of this pathogen into new locations and hosts has been shown to produce high morbidity and mortality, a situation observed recently in Australian and North American wildlife.Of the seven native animal species in Australia known to be infested by S. scabiei, the bare-nosed wombat (Vombatus ursinus) suffers the greatest with significant population declines having been observed in New South Wales and Tasmania. The origins of sarcoptic mange in Australian native animals are poorly understood, with the most consistent conclusion being that mange was introduced by settlers and their dogs and subsequently becoming a major burden to native wildlife. Four studies exist addressing the origins of mange in Australia, but all Australian S. scabiei samples derive from only two of these studies. This review highlights this paucity of phylogenetic knowledge of S. scabiei within Australia, and suggests further research is needed to confidently determine the origin, or multiple origins, of this parasite.At the global scale, numerous genetic studies have attempted to reveal how the host species and host geographic location influence S. scabiei phylogenetics. This review includes an analysis of the global literature, revealing that inconsistent use of gene loci across studies significantly influences phylogenetic inference. Furthermore, by performing a contemporary analytical approach on existing data, it is apparent that (i) new S. scabiei samples, (ii) appropriate gene loci targets, and (iii) advanced phylogenetic approaches are necessary to more confidently comprehend the origins of mange in Australia. Advancing this field of research will aid in understanding the mechanisms of spillover for mange and other parasites globally.

  7. Mass communication and cultural identity: the unresolved issue of national sovereignty and cultural autonomy in the wake of new communication technologies.

    PubMed

    Uche, L U

    1988-01-01

    The trend in modern mass communication appears to be toward the imposition of the cultural, economic, and political values of the societies with the most advanced communication and information technologies and media sources. The consequence of this reality is that the cultural values, national aspirations, economic needs, and political independence of developing countries are not taken into consideration. Thus, the national interests of African states make it imperative for them to carefully evaluate, assess, and examine the development of their present media structures and ownership patterns. If the mass media is privatized, their owners serve as mouthpieces for multinational corporations. This phenomenon can severely undermine African goals of self-sufficiency in food production and industrialization, political stability that guarantees territorial integrity, and preservation of the African culture. It is imperative that African governments do not allow big multinationals to take over the molding and control of public opinion. Although modern systems of communication are exceedingly expensive and sophisticated, ways must be found to make the media public utilities.

  8. Residents' diverse perspectives of the impact of neighbourhood renewal on quality of life and physical activity engagement: Improvements but unresolved issues

    PubMed Central

    Coulson, J.C.; Fox, K.R.; Lawlor, D.A.; Trayers, T.

    2011-01-01

    Few studies have been published on the reactions of residents to modifications of their residential landscape. We explored residents' experiences of home zone remodelling and construction of a new cycle-walkway in a deprived neighbourhood with a particular focus on aspects of quality of life and physical activity participation. Focus groups (n=5 groups, 21 individuals) were used to investigate residents' perceptions of the effects of neighbourhood change on their lives. Consultation by planners was received positively. Several aspects of the neighbourhood were perceived to have improved, including spatial aesthetics, lighting and streetscape planting. However, influence on physical activity was minimal. Car-focused behaviour and ownership remained dominant, and safety related concerns limited behavioural choices. Residents highlighted many socio-environmental challenges that remained such as sense of neighbourhood safety, poor public transport provision, people's parking behaviour locally, and problem neighbours, and these tended to dominate conversations. Infrastructural intervention may be one important part of multi-layered solutions to improved neighbourhood life. PMID:21145277

  9. Unaddressed Issues

    ERIC Educational Resources Information Center

    Rochester, J. Martin

    2005-01-01

    Walter Parker's January article, "Teaching Against Idiocy," raises important and fascinating issues relating to the proper role and function of the K-12 social studies classroom. Although J. Martin Rochester, the author of this article, agrees with his basic premise that schools obviously have an obligation to help promote citizenship education,…

  10. Faculty Issues.

    ERIC Educational Resources Information Center

    Finkelstein, Martin

    Patterns that emerged from reviewing syllabi for courses on faculty issues are discussed, and four sample syllabi are presented. Few doctoral programs in higher education administration were identified that devote an entire course to the subject of American college and university faculty. For four courses that did devote an entire course to the…

  11. USSOCOM’s Role in Addressing Human Trafficking

    DTIC Science & Technology

    2010-12-02

    modern slavery . Its size, global scope, and potential to threaten national security warrants appropriate Department of Defense attention. However, the...manifests itself in slavery – indefensible abuse of the vulnerable by the more powerful. Addressing this issue will require a systemic and sustained... slavery today rivals that of the eighteenth and nineteenth centuries, that naïveté cannot prevent purposeful action to address the modern form of

  12. Addressing problems in complete dentures.

    PubMed

    LaBarre, Eugene; Giusti, Lola; Pitigoi-Aron, Gabriela

    2007-10-01

    The authors have compiled a set of solutions to the most common issues influencing the success of complete denture cases. A brief review and discussion of occlusal vertical dimension is presented, followed by a troubleshooting guide to problems such as inadequate retention and stability, discomfort, and other problems affecting treatment outcome.

  13. Addressing Breast Cancer's Unequal Burden

    MedlinePlus

    ... be useful for all women. How will the study work? The initiative will gather data from 18 smaller studies. While some of these studies were able to ... future cancer research among minority populations. Dr. Martin's work seeks to ... women in breast cancer studies? Historically, trust has been a key issue in ...

  14. Women's Issues Are Economic Issues.

    ERIC Educational Resources Information Center

    Schroeder, Patricia

    1983-01-01

    Faulty laws, unfair practices, and years of tradition in the workplace keep women from economic equality. The Economic Equity Act proposed by Congress will address inequalities in tax and retirement matters, the need for better dependent care, nondiscrimination in insurance, regulatory reform, and child support enforcement. (IS)

  15. Introduction: Progress and issues in drug treatment courts.

    PubMed

    Harrison, Lana D; Scarpitti, Frank R

    2002-01-01

    The first drug treatment court began in Miami, Florida in 1989, in direct response to the backlog of court cases for drug possession and trafficking. By mid-2001, there were 700 operational drug treatment courts and 400 more in the planning stages in the United States. In addition to providing an overview of the growth and development of drug treatment courts in the United States, this special issue examines their development in Australia, Canada, and the United Kingdom. The primary focus is the evaluation research conducted to date, which identifies some of the critical unresolved issues facing drug treatment courts.

  16. Atomic clusters with addressable complexity

    NASA Astrophysics Data System (ADS)

    Wales, David J.

    2017-02-01

    A general formulation for constructing addressable atomic clusters is introduced, based on one or more reference structures. By modifying the well depths in a given interatomic potential in favour of nearest-neighbour interactions that are defined in the reference(s), the potential energy landscape can be biased to make a particular permutational isomer the global minimum. The magnitude of the bias changes the resulting potential energy landscape systematically, providing a framework to produce clusters that should self-organise efficiently into the target structure. These features are illustrated for small systems, where all the relevant local minima and transition states can be identified, and for the low-energy regions of the landscape for larger clusters. For a 55-particle cluster, it is possible to design a target structure from a transition state of the original potential and to retain this structure in a doubly addressable landscape. Disconnectivity graphs based on local minima that have no direct connections to a lower minimum provide a helpful way to visualise the larger databases. These minima correspond to the termini of monotonic sequences, which always proceed downhill in terms of potential energy, and we identify them as a class of biminimum. Multiple copies of the target cluster are treated by adding a repulsive term between particles with the same address to maintain distinguishable targets upon aggregation. By tuning the magnitude of this term, it is possible to create assemblies of the target cluster corresponding to a variety of structures, including rings and chains.

  17. Issues in Media Ethics. ERIC Digest.

    ERIC Educational Resources Information Center

    Aiex, Nola Kortner; Gottlieb, Stephen S.

    Noting that over the past decade incidents have occurred and new technologies have appeared which together have raised questions about the ethical values of American journalists, this Digest seeks to identify some of those ethical issues and to point to the work of those who have studied these issues. It addresses issues of plagiarism and…

  18. Teaching Social Issues in the English Classroom.

    ERIC Educational Resources Information Center

    Totten, Samuel, Ed.

    1986-01-01

    Focusing on the rationales and materials for teaching social issues in the English classroom, this thematic issue contains the following articles: "Introduction: Reflections of Society in Literature" (M. B. Fleming); "Addressing Social and/or Controversial Issues in the English Classroom" (S. Totten); "The Growing Threat to Quality Education: How…

  19. Environmental Issues are Controversial Issues.

    ERIC Educational Resources Information Center

    Hepburn, Mary Allaire

    The extensive social-scientific interest and continuing relevance of environmental study assure its immediate and long-range importance in the social studies. But the crisis atmosphere surrounding this issue threatens a thoughtful, systematic approach to the subject, and poses the danger of a careless rush to activity. As social studies educators,…

  20. Defusion: A Behavior-Analytic Strategy for Addressing Private Events

    PubMed Central

    Snyder, Katie; Lambert, Joseph; Twohig, Michael P

    2011-01-01

    Applied behavior analysts encounter situations in which private events hinder client progress, and additional techniques to address these issues are needed. By conceptualizing private events as verbal rules, we provide a behavior-analytic framework for understanding and addressing these events. Relational frame theory (RFT) is the basis for this conceptual foundation; the empirically based principles of RFT are presented along with direct implications for understanding private events. Defusion, an RFT-based technique for addressing private events, is then described and empirical studies that evaluate the effects of defusion are reviewed. Finally, potential clinical applications for practicing behavior analysts are offered. PMID:22649574

  1. Advancing efforts to address youth violence involvement.

    PubMed

    Weist, M D; Cooley-Quille, M

    2001-06-01

    Discusses the increased public attention on violence-related problems among youth and the concomitant increased diversity in research. Youth violence involvement is a complex construct that includes violence experienced in multiple settings (home, school, neighborhood) and in multiple forms (as victims, witnesses, perpetrators, and through family members, friends, and the media). Potential impacts of such violence involvement are considerable, including increased internalizing and externalizing behaviors among youth and future problems in school adjustment and life-course development. This introductory article reviews key dimensions of youth-related violence, describes an American Psychological Association Task Force (Division 12) developed to advance relevant research, and presents examples of national resources and efforts that attempt to address this critical public health issue.

  2. Theoretical Issues

    SciTech Connect

    Marc Vanderhaeghen

    2007-04-01

    The theoretical issues in the interpretation of the precision measurements of the nucleon-to-Delta transition by means of electromagnetic probes are highlighted. The results of these measurements are confronted with the state-of-the-art calculations based on chiral effective-field theories (EFT), lattice QCD, large-Nc relations, perturbative QCD, and QCD-inspired models. The link of the nucleon-to-Delta form factors to generalized parton distributions (GPDs) is also discussed.

  3. Policy issues in interconnecting networks

    NASA Technical Reports Server (NTRS)

    Leiner, Barry M.

    1989-01-01

    To support the activities of the Federal Research Coordinating Committee (FRICC) in creating an interconnected set of networks to serve the research community, two workshops were held to address the technical support of policy issues that arise when interconnecting such networks. The workshops addressed the required and feasible technologies and architectures that could be used to satisfy the desired policies for interconnection. The results of the workshop are documented.

  4. Opportunities and challenges of using technology to address health disparities.

    PubMed

    Rivers, Brian M; Bernhardt, Jay M; Fleisher, Linda; Green, Bernard Lee

    2014-03-01

    During a panel presentation at the American Association for Cancer Research Cancer Health Disparities Conference titled 'Opportunities and challenges of using technology to address health disparities', the latest scientific advances in the application and utilization of mobile technology and/or mobile-health (mHealth) interventions to address cancer health disparities were discussed. The session included: an examination of overall population trends in the uptake of technology and the potential of addressing health disparities through such media; an exploration of the conceptual issues and challenges in the construction of mHealth interventions to address disparate and underserved populations; and a presentation of pilot study findings on the acceptability and feasibility of using mHealth interventions to address prostate cancer disparities among African-American men.

  5. Space station human productivity study. Volume 4: Issues

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The 305 Issues contained represent topics recommended for study in order to develop requirements in support of space station crew performance/productivity. The overall subject matter, space station elements affecting crew productivity, was organized into a coded subelement listing, which is included for the reader's reference. Each issue is numbered according to the 5-digit topical coding scheme. The requirements column on each Issue page shows a cross-reference to the unresolved requirement statement(s). Because topical overlaps were frequently encountered, many initial Issues were consolidated. Apparent gaps, therefore, may be accounted for by an Issue described within a related subelement. A glossary of abbreviations used throughout the study documentation is also included.

  6. Identifying and Addressing Vaccine Hesitancy

    PubMed Central

    Kestenbaum, Lori A.; Feemster, Kristen A.

    2015-01-01

    In the 20th century, the introduction of multiple vaccines significantly reduced childhood morbidity, mortality, and disease outbreaks. Despite, and perhaps because of, their public health impact, an increasing number of parents and patients are choosing to delay or refuse vaccines. These individuals are described as vaccine hesitant. This phenomenon has developed due to the confluence of multiple social, cultural, political and personal factors. As immunization programs continue to expand, understanding and addressing vaccine hesitancy will be crucial to their successful implementation. This review explores the history of vaccine hesitancy, its causes, and suggested approaches for reducing hesitancy and strengthening vaccine acceptance. PMID:25875982

  7. Identifying and addressing vaccine hesitancy.

    PubMed

    Kestenbaum, Lori A; Feemster, Kristen A

    2015-04-01

    In the 20th century, the introduction of multiple vaccines significantly reduced childhood morbidity, mortality, and disease outbreaks. Despite, and perhaps because of, their public health impact, an increasing number of parents and patients are choosing to delay or refuse vaccines. These individuals are described as "vaccine hesitant." This phenomenon has developed due to the confluence of multiple social, cultural, political, and personal factors. As immunization programs continue to expand, understanding and addressing vaccine hesitancy will be crucial to their successful implementation. This review explores the history of vaccine hesitancy, its causes, and suggested approaches for reducing hesitancy and strengthening vaccine acceptance.

  8. Nanoscale content-addressable memory

    NASA Technical Reports Server (NTRS)

    Davis, Bryan (Inventor); Principe, Jose C. (Inventor); Fortes, Jose (Inventor)

    2009-01-01

    A combined content addressable memory device and memory interface is provided. The combined device and interface includes one or more one molecular wire crossbar memories having spaced-apart key nanowires, spaced-apart value nanowires adjacent to the key nanowires, and configurable switches between the key nanowires and the value nanowires. The combination further includes a key microwire-nanowire grid (key MNG) electrically connected to the spaced-apart key nanowires, and a value microwire-nanowire grid (value MNG) electrically connected to the spaced-apart value nanowires. A key or value MNGs selects multiple nanowires for a given key or value.

  9. Addressing inequities in healthy eating.

    PubMed

    Friel, Sharon; Hattersley, Libby; Ford, Laura; O'Rourke, Kerryn

    2015-09-01

    What, when, where and how much people eat is influenced by a complex mix of factors at societal, community and individual levels. These influences operate both directly through the food system and indirectly through political, economic, social and cultural pathways that cause social stratification and influence the quality of conditions in which people live their lives. These factors are the social determinants of inequities in healthy eating. This paper provides an overview of the current evidence base for addressing these determinants and for the promotion of equity in healthy eating.

  10. Addressing the workforce pipeline challenge

    SciTech Connect

    Leonard Bond; Kevin Kostelnik; Richard Holman

    2006-11-01

    A secure and affordable energy supply is essential for achieving U.S. national security, in continuing U.S. prosperity and in laying the foundations to enable future economic growth. To meet this goal the next generation energy workforce in the U.S., in particular those needed to support instrumentation, controls and advanced operations and maintenance, is a critical element. The workforce is aging and a new workforce pipeline, to support both current generation and new build has yet to be established. The paper reviews the challenges and some actions being taken to address this need.

  11. Addressing Cultural and Native Language Interference in Second Language Acquisition

    ERIC Educational Resources Information Center

    Allard, Daniele; Bourdeau, Jacqueline; Mizoguchi, Riichiro

    2011-01-01

    This paper addresses the problem of cultural and native language interference in second/foreign language acquisition. More specifically, it examines issues of interference that can be traced to a student's native language and that also have a cultural component. To this effect, an understanding of what actually comprises both interference and…

  12. Addressing the Mathematics-Specific Needs of Beginning Mathematics Teachers

    ERIC Educational Resources Information Center

    Britton, Edward

    2012-01-01

    Beginning mathematics teachers at the secondary level (middle and high school grades) have mathematics-specific needs that induction programs should address more substantially. However, a number of issues in how programs can accomplish this are more complex than often framed in discussions occurring in the induction programs and the field of…

  13. EPA Addresses Environmental Justice in Espaola, N.M.

    EPA Pesticide Factsheets

    DALLAS - (Oct. 8, 2015) Today, the U.S. Environmental Protection Agency (EPA) announced TEWA Woman United was selected as a grant recipient to address environmental justice (EJ) issues in Española, N. M. The grant enables the organization to cond

  14. Using Applied Theatre as a Tool to Address Netizenship

    ERIC Educational Resources Information Center

    Skeiker, Fadi Fayad

    2015-01-01

    This paper charts the ways in which a researcher uses applied theatre practice as a tool to address netizenship issues in the advancement of digital age by documenting a workshop he co-facilitated with graduate students at the University of Porto during the Future Places conference in 2013. The workshop used applied theatre both to catalyze…

  15. Effective Language Education Practices and Native Language Survival. Keynote Address.

    ERIC Educational Resources Information Center

    Littlebear, Dick

    The importance of Native languages to Native Americans and the effort needed to maintain them are discussed in this keynote address at the ninth Native American Language Issues Institute. It is noted that the current cultural transition has demeaned Native languages and cultures and that strategies must be devised by Native Americans to counter…

  16. Addressing the Need for Electronic Communication in Foreign Language Teaching.

    ERIC Educational Resources Information Center

    LeLoup, Jean W.; Ponterio, Robert

    Use of electronic communication options to access foreign language teaching resources is discussed, illustrated with examples from programs and applications found in New York State. The discussion is divided into four sections, each addressing an aspect of electronic communication for preparing for and teaching a foreign language: issues of access…

  17. Neglected issues and voices.

    PubMed

    Pittaway, E; Bartolomei, L; Rees, S

    2007-01-01

    The 2004 Tsunami highlighted the silence which surrounds gender issues, in particular the incidence of rape and sexual abuse of women and girls displaced by natural disasters and conflict. They include lack of recognition of women's sanitation needs, the need for safe, private places to bathe, secure spaces for single women and girls, lack of contraception, accessible sexual and reproductive health care, and legal measures to be taken against men who rape and abuse women. Reports of violence against women and increased domestic violence have been documented in all tsunami affected countries. Women from across the affected region came together in New York, March 2005 at the meeting of the UN Commission for the Status of Women to review the implementation of the Beijing Platform for Action. Through their efforts at that meeting, a United Nations Resolution was passed in which Governments made commitments to address gender issues and sexual abuse in disaster situations.

  18. Issues in physician contracting.

    PubMed

    Fanburg, John D; Leone, Alyson M

    2005-09-01

    Dermatologists will enter into a number of different contracts during their professional careers. It is important that in each agreement they enter, dermatologists reap the benefits that they aspire for and understand the consequences of each provision. This article addresses just a few of the different issues that arise in physician contracting, such as choosing the appropriate form of business entity; the importance of a writing; term and termination of the contract; compensation models; benefits, vacation and other time off included in the contract; malpractice insurance; and restrictive covenants. Each provision should be carefully analyzed to ensure that it will protect the best interests of the dermatologist in that situation.

  19. Introduction to the special issue on aquifer-sedimentology: problems, perspectives and modern approaches

    NASA Astrophysics Data System (ADS)

    Huggenberger, Peter; Aigner, Tom

    1999-12-01

    Progress towards a better understanding of groundwater circulation and transport processes in aquifers demands a multidisciplinary approach to a host of unresolved problems. Although much progress has been made within recent years in interpreting the dynamic character of groundwater systems, many key issues remain to be addressed. In particular, several areas demand attention: the role of sedimentological information (heterogeneity) in groundwater and transport models, the scaling-up of observations from outcrop scale to larger scales and the integration of geological and geophysical information of different quality into the description of an aquifer structure. Still nowadays many of the heterogeneities cannot be recognized directly because of the limitation of measurement techniques. This is probably one of the reasons for the limited application of aquifer-sedimentology and geophysics in practical cases. In order to consolidate, expand, and make a larger number of people aware of the contribution of modern aquifer-sedimentology, including modelling and ultra-high resolution geophysical methods, several lines of intervention were identified: (1) a better collaboration of the different disciplines on site-specific applied problems; (2) development of new modelling techniques combining data of different quality; (3) development of optimizing tools (position and number of wells, additional geophysical methods, baysian techniques); (4) development of a `common language' among sedimentologists and hydrogeologists to overcome communication problems.

  20. Promising evidence and remaining issues regarding the clinical application of oxytocin in autism spectrum disorders.

    PubMed

    Yamasue, Hidenori

    2016-02-01

    Oxytocin is a potential therapeutic for the core symptoms of autism spectrum disorder (ASD), which is currently untreatable with pharmacotherapy. Previous clinical trials of a single dose of oxytocin have consistently reported significantly positive effects on various experimental measures associated with the core symptoms of ASD. These studies used various experimental measures as surrogate endpoints of the trials. However, to date, randomized clinical trials of continual administration of oxytocin have failed to reveal significant positive effects on clinically meaningful endpoints, such as how those with ASD interact during interpersonal interactions. This article reviews both the negative and positive effects of oxytocin on the core symptoms of ASD and their surrogate markers. Some unresolved and critical issues on the development of oxytocin as a new therapeutic have been extracted: optimization of dose, duration of oxytocin treatment, and the development of objective and reliable measurements of clinically meaningful endpoints for the core symptoms of ASD. Furthermore, optimization to the intranasal delivery system and careful consideration of how individuals respond differently to treatments should be addressed in future studies.