Esophageal motor function: technical aspects of manometry.

PubMed

Gyawali, C Prakash; Patel, Amit

2014-10-01

High-resolution manometry (HRM) has advanced the understanding of esophageal peristaltic mechanisms and has simplified esophageal motor testing. In this article the technical aspects of HRM are addressed, focusing on test protocols, in addition to concerns and pitfalls in performing esophageal motor studies. Specifically, catheter positioning, equipment-related artifacts, basal data acquisition, adequate swallows, and provocative maneuvers are discussed. Copyright © 2014 Elsevier Inc. All rights reserved.

Job Enrichment: Possible Criteria for Application in Air Force Organizations.

ERIC Educational Resources Information Center

Clarke, Richard L.; Pesenti, Peter T.

The basic problem addressed by this thesis was the identification of specific criteria for determining the applicability of a job enrichment program in a specific career area. Identifying criteria involved the intrinsic and extrinsic aspects of a job, which act as determiners of job satisfaction or dissatisfaction. Survey data were obtained using…

SFO wake turbulence measurement system : sensors and data descriptions

DOT National Transportation Integrated Search

2006-10-01

This report addresses aspects of an extensive aircraft wake turbulence measurement program conducted at San Francisco : International Airport (SFO) over a two-year period. Specifically, this report describes the sensors used for data collection and t...

Pediatric Psychosocial Oncology: A Quick Reference on the Psychosocial Dimensions of Cancer Symptom Management | Center for Cancer Research

Cancer.gov

The 2nd Edition of the handbook, Pediatric Psycho-Oncology: A Quick Reference on the Psychosocial Dimensions of Cancer Symptom Management, by Oxford Press, 2015 fills an important niche, as it provides practical hands-on information on many aspects of psychological and psychiatric aspects of pediatric oncology care.  It is organized with sections addressing specific clinical

Geophysical study of the structure and processes of the continental convergence zones: Alpine-Himalayan Belt

NASA Technical Reports Server (NTRS)

Toksoz, M. Nafi; Molnar, Peter

1988-01-01

Intracontinental deformation occurrence and the processes and physical parameters that control the rates and styles of deformation were examined. Studies addressing specific mechanical aspects of deformation were reviewed and the studies of deformation and of the structure of specific areas were studied considering the strength of the material and the gravitational effect.

Tangent to Experimental Techniques of Verbal Control.

ERIC Educational Resources Information Center

Bilodeau, Ina McD.

This paper is a critical comment and reaction to a 1965 article by G. A. Miller entitled "Some Preliminaries to Psycholinguistics." The subject matter is verbal control of behavior. Seven specific aspects of the Miller address are discussed. (WD)

Differential Dynamics of Amino Acid Release in the Amygdala and Olfactory Cortex during Odor Fear Acquisition as Revealed with Simultaneous High Temporal Resolution Microdialysis

ERIC Educational Resources Information Center

Hegoburu, Chloe; Sevelinges, Yannick; Thevenet, Marc; Gervais, Remi; Parrot, Sandrine; Mouly, Anne-Marie

2009-01-01

Although the amygdala seems to be essential to the formation and storage of fear memories, it might store only some aspects of the aversive event and facilitate the storage of more specific sensory aspects in cortical areas. We addressed the time course of amygdala and cortical activation in the context of odor fear conditioning in rats. Using…

Multicultural Issues and Concerns in Library Education.

ERIC Educational Resources Information Center

Freiband, Susan J.

1992-01-01

Identifies multilingual and multicultural issues relevant to library and information science curricula today and outlines the skills, knowledge, and attitudes needed by graduates to address these issues. Aspects of the curriculum, specific programs, and activities on which to focus are discussed. (13 references) (EA)

Alcoholism among Psychologists: A Review of the Literature.

ERIC Educational Resources Information Center

French, Rebecca J.

Alcoholism, a major health problem currently being addressed by other professions, has unique features, manifestations, and ramifications for psychologists. Salient aspects of alcoholism in psychology include etiological and motivational factors, characteristic behaviors, and specific risk factors in the work environment of psychologists.…

Mathematical aspects of finite element methods for incompressible viscous flows

NASA Technical Reports Server (NTRS)

Gunzburger, M. D.

1986-01-01

Mathematical aspects of finite element methods are surveyed for incompressible viscous flows, concentrating on the steady primitive variable formulation. The discretization of a weak formulation of the Navier-Stokes equations are addressed, then the stability condition is considered, the satisfaction of which insures the stability of the approximation. Specific choices of finite element spaces for the velocity and pressure are then discussed. Finally, the connection between different weak formulations and a variety of boundary conditions is explored.

Quality and Safety Aspects of Cereals (Wheat) and Their Products.

PubMed

Varzakas, Theo

2016-11-17

Cereals and, most specifically, wheat are described in this chapter highlighting on their safety and quality aspects. Moreover, wheat quality aspects are adequately addressed since they are used to characterize dough properties and baking quality. Determination of dough properties is also mentioned and pasta quality is also described in this chapter. Chemometrics-multivariate analysis is one of the analyses carried out. Regarding production weighing/mixing of flours, kneading, extruded wheat flours, and sodium chloride are important processing steps/raw materials used in the manufacturing of pastry products. Staling of cereal-based products is also taken into account. Finally, safety aspects of cereal-based products are well documented with special emphasis on mycotoxins, acrylamide, and near infrared methodology.

Platform-dependent optimization considerations for mHealth applications

NASA Astrophysics Data System (ADS)

Kaghyan, Sahak; Akopian, David; Sarukhanyan, Hakob

2015-03-01

Modern mobile devices contain integrated sensors that enable multitude of applications in such fields as mobile health (mHealth), entertainment, sports, etc. Human physical activity monitoring is one of such the emerging applications. There exists a range of challenges that relate to activity monitoring tasks, and, particularly, exploiting optimal solutions and architectures for respective mobile software application development. This work addresses mobile computations related to integrated inertial sensors for activity monitoring, such as accelerometers, gyroscopes, integrated global positioning system (GPS) and WLAN-based positioning, that can be used for activity monitoring. Some of the aspects will be discussed in this paper. Each of the sensing data sources has its own characteristics such as specific data formats, data rates, signal acquisition durations etc., and these specifications affect energy consumption. Energy consumption significantly varies as sensor data acquisition is followed by data analysis including various transformations and signal processing algorithms. This paper will address several aspects of more optimal activity monitoring implementations exploiting state-of-the-art capabilities of modern platforms.

Cultural Sensitivity and Challenges in Management of the Transgender Patient With ESRD in Transplantation.

PubMed

Hoch, Deborah Ann; Bulman, Maya; McMahon, Dorn W

2016-03-01

Transgender patients with end-stage renal disease (ESRD) present with specific challenges during the transplant evaluation, perioperative management, and postoperative phase of care. Demographic information, health-care records, chosen name, and gender identity along with documentation of specific health-care needs can become a challenge when gender assigned at birth is incongruent with the patients gender identity. Medical care involves addressing the end-organ disease as well as addressing those aspects of care specific to the transgender patient. This review article provides information on defining transgender, the impact of ESRD, and transgender in the transplant process and considerations in the throughout phases of care. Current recommendations for management of this unique population are provided. © 2016, NATCO.

Inclusion of social indicators in decision support tools for the selection of sustainable site remediation options.

PubMed

Cappuyns, Valérie

2016-12-15

Sustainable remediation requires a balanced decision-making process in which environmental, economic and social aspects of different remediation options are all considered together and the optimum remediation solution is selected. More attention has been paid to the evaluation of environmental and economic aspects, in particular to reduce the human and environmental risks and the remediation costs, to the exclusion of social aspects of remediation. This paper investigates how social aspects are currently considered in sustainability assessments of remediation projects. A selection of decision support tools (DSTs), used for the sustainability assessment of a remediation project, is analyzed to define how social aspects are considered in those tools. The social indicator categories of the Sustainable Remediation Forum - United Kingdom (SuRF-UK), are used as a basis for this evaluation. The consideration of social aspects in the investigated decision support tools is limited, but a clear increase is noticed in more recently developed tools. Among the five social indicator categories defined by SuRF-UK to facilitate a holistic consideration of social aspects of a remediation project only "Human health and safety" is systematically taken into account. "Neighbourhood and locality" is also often addressed, mostly emphasizing the potential disturbance caused by the remediation activities. However, the evaluation of 'Ethics and Equality', Communities and community involvement', and 'Uncertainty and evidence' is often neglected. Nevertheless, concrete examples can be found in some of the investigated tools. Specific legislation, standard procedures, and guidelines that have to be followed in a region or country are mainly been set up in the context of protecting human and ecosystem health, safety and prevention of nuisance. However, they sometimes already include some of the aspects addressed by the social indicators. In this perspective the use of DST to evaluate the sustainability of a site remediation project, should be tuned to the legislation, guidelines and procedures that are in force in a specific country or region. Copyright © 2016 Elsevier Ltd. All rights reserved.

Workforce Investment Act: Labor has Made Progress in Addressing Areas of Concern, but More Focus Needed on Understanding What Works and What Doesn't. Testimony Before the Subcommittee on Higher Education, Lifelong Learning, and Competitiveness, Committee on Education and Labor, House of Representatives. GAO-09-396T

ERIC Educational Resources Information Center

Scott, George A.

2009-01-01

Since the Workforce Investment Act's (WIA) enactment in 1998, GAO has issued numerous reports that included recommendations regarding many aspects of WIA. These aspects include performance measures and accountability, funding formulas and spending, one-stop centers, and training, as well as services provided to specific populations, such as…

How to Measure Outcomes of Peripheral Nerve Surgery

PubMed Central

Wang, Yirong; Sunitha, Malay; Chung, Kevin C.

2013-01-01

Synopsis Evaluation of outcomes after peripheral nerve surgeries include a number of assessment methods that reflect different aspects of recovery, including reinnervation, tactile gnosis, integrated sensory and motor function, pain and discomfort, neurophysiological and patient- reported outcomes. This review makes a list of measurements addressing these aspects as well as advantage and disadvantage of each tool. Because of complexities of neurophysiology, assessment remains a difficult process, which requires researchers focus on measurements best relevant to specific conditions and research questions. PMID:23895715

Ultraviolet and near-infrared femtosecond temporal pulse shaping with a new high-aspect-ratio one-dimensional micromirror array.

PubMed

Weber, Stefan M; Extermann, Jérôme; Bonacina, Luigi; Noell, Wilfried; Kiselev, Denis; Waldis, Severin; de Rooij, Nico F; Wolf, Jean-Pierre

2010-09-15

We demonstrate the capabilities of a new optical microelectromechanical systems device that we specifically developed for broadband femtosecond pulse shaping. It consists of a one-dimensional array of 100 independently addressable, high-aspect-ratio micromirrors with up to 3 μm stroke. We apply linear and quadratic phase modulations demonstrating the temporal compression of 800 and 400 nm pulses. Because of the device's surface flatness, stroke, and stroke resolution, phase shaping over an unprecedented bandwidth is attainable.

How to measure outcomes of peripheral nerve surgery.

PubMed

Wang, Yirong; Sunitha, Malay; Chung, Kevin C

2013-08-01

Evaluation of outcomes after peripheral nerve surgeries include several assessment methods that reflect different aspects of recovery, including reinnervation, tactile gnosis, integrated sensory and motor function, pain and discomfort, and neurophysiologic and patient-reported outcomes. This review lists measurements addressing these aspects as well as the advantages and disadvantages of each tool. Because of complexities of neurophysiology, assessment remains a difficult process, which requires researchers to focus on measurements best relevant to specific conditions and research questions. Copyright © 2013 Elsevier Inc. All rights reserved.

Evaluating, Selecting, and Using Appropriate Assistive Technology.

ERIC Educational Resources Information Center

Galvin, Jan C.; Scherer, Marcia J.

This book addresses all aspects of assistive technology for individuals with disabilities, including policy, legislation, funding, evaluation, selection, and maintenance. Ten of the 15 chapters are written by individuals with disabilities and cover topics related to the use of technology in education, employment, and play. Specific chapters…

President's Role in Economic Development.

ERIC Educational Resources Information Center

Kopecek, Robert J.

This document focuses on the role of community college presidents in the varied activities entailed by economic development. Specifically, the paper addresses those activities that involve the political, financial, and economic aspects of regional or county planning, marketing and financing. First, definitions are provided of two types of economic…

Vertical Lift - Not Just For Terrestrial Flight

NASA Technical Reports Server (NTRS)

Young, Larry A

2000-01-01

Autonomous vertical lift vehicles hold considerable potential for supporting planetary science and exploration missions. This paper discusses several technical aspects of vertical lift planetary aerial vehicles in general, and specifically addresses technical challenges and work to date examining notional vertical lift vehicles for Mars, Titan, and Venus exploration.

Practical Handbook of School Psychology: Effective Practices for the 21st Century

ERIC Educational Resources Information Center

Peacock, Gretchen Gimpel, Ed.; Ervin, Ruth A., Ed.; Daly, Edward J., III, Ed.; Merrell, Kenneth W., Ed.

2009-01-01

This authoritative guide addresses all aspects of school psychology practice in a response-to-intervention (RTI) framework. Thirty-four focused chapters present effective methods for problem-solving-based assessment, instruction, and intervention. Specific guidelines are provided for promoting success in core academic domains--reading, writing,…

Adolescent Behavior and Health in Cross-Cultural Context

ERIC Educational Resources Information Center

Demetrovics, Zsolt

2012-01-01

Specific behavioral problems appear during early adolescence, and they become more pronounced. Although these problems are universal in many aspects, cultural differences are also conspicuous. The author, in addition to analyzing the five studies in the Special Issue, addresses questions concerning the cross-cultural context. The analysis reveals…

The Practice of Foreign Language Teaching.

ERIC Educational Resources Information Center

Cajkler, Wasyl; Addelman, Ron

This book on aspects of modern foreign language teaching is written for trainee, new, and experienced teachers of students aged 11-16 and is intended as a practical source of information. The discussion of specific teaching issues includes implications for classroom practice. While not directly addressing Britain's new National Curriculum, it does…

Domain 2: Sport Safety and Injury Prevention

ERIC Educational Resources Information Center

Gurchiek, Larry; Mokha, Monique Butcher

2004-01-01

Most coaches recognize the importance of creating a safe environment and preventing injuries of their athletes. Domain 2 is dedicated to this important aspect of coaching, and outlines specific areas within safety and injury prevention that coaches should address. Domain 2 sets the standards for facility, equipment, and environmental safety…

Design of Educational Delivery Systems for Lifelong Learning.

ERIC Educational Resources Information Center

Gibson, R. Oliver; Gilbert, Randall L.

To clarify delivery system concepts, several topics will be addressed: educational needs of lower-income older people, formulation of a design concept, specification of the system's concrete aspects, and research/development implications. As the proportion of persons over age sixty-four grows and sensitivity to unmet lifelong learning needs rises,…

Development of Specific Aspects of Spirituality during a 6-Month Intensive Yoga Practice

PubMed Central

Büssing, Arndt; Hedtstück, Anemone; Khalsa, Sat Bir S.; Ostermann, Thomas; Heusser, Peter

2012-01-01

The majority of research on yoga focuses on its psychophysiological and therapeutic benefits, while the spiritual aspects are rarely addressed. Changes of specific aspects of spirituality were thus investigated among 160 individuals (91% women, mean age 40.9 ± 8.3 years; 57% Christians) starting a 2-year yoga teacher training. We used standardized questionnaires to measure aspects of spirituality (ASP), mindfulness (FMI—Freiburg Mindfulness Inventory), life satisfaction (BMLSS—Brief Multidimensional Life Satisfaction Scale), and positive mood (lightheartedness/relief). At the start of the course, scores of the respective ASP subscales for search for insight/wisdom, transcendence conviction, and conscious interactions/compassion were high, while those for religious orientation were low. Within the 6 month observation period, both conscious interactions/compassion (effect size, Cohen's d = .33), Religious orientation (d = .21), Lightheartedness/Relief (d = .75) and mindfulness (d = .53) increased significantly. Particularly non-religious/non-spiritual individuals showed moderate effects for an increase of conscious interactions/compassion. The results from this study suggest that an intensive yoga practice (1) may significantly increase specific aspects of practitioners' spirituality, mindfulness, and mood, (2) that these changes are dependent in part on their original spiritual/religious self-perception, and (3) that there are strong correlations amongst these constructs (i.e., conscious interactions/compassion, and mindfulness). PMID:22852023

A framework for multi-criteria assessment of model enhancements

NASA Astrophysics Data System (ADS)

Francke, Till; Foerster, Saskia; Brosinsky, Arlena; Delgado, José; Güntner, Andreas; López-Tarazón, José A.; Bronstert, Axel

2016-04-01

Modellers are often faced with unsatisfactory model performance for a specific setup of a hydrological model. In these cases, the modeller may try to improve the setup by addressing selected causes for the model errors (i.e. data errors, structural errors). This leads to adding certain "model enhancements" (MEs), e.g. climate data based on more monitoring stations, improved calibration data, modifications in process formulations. However, deciding on which MEs to implement remains a matter of expert knowledge, guided by some sensitivity analysis at best. When multiple MEs have been implemented, a resulting improvement in model performance is not easily attributed, especially when considering different aspects of this improvement (e.g. better performance dynamics vs. reduced bias). In this study we present an approach for comparing the effect of multiple MEs in the face of multiple improvement aspects. A stepwise selection approach and structured plots help in addressing the multidimensionality of the problem. The approach is applied to a case study, which employs the meso-scale hydrosedimentological model WASA-SED for a sub-humid catchment. The results suggest that the effect of the MEs is quite diverse, with some MEs (e.g. augmented rainfall data) cause improvements for almost all aspects, while the effect of other MEs is restricted to few aspects or even deteriorate some. These specific results may not be generalizable. However, we suggest that based on studies like this, identifying the most promising MEs to implement may be facilitated.

Introspection of subjective feelings is sensitive and specific.

PubMed

Questienne, Laurence; van Dijck, Jean-Philippe; Gevers, Wim

2018-02-01

Conversely to behaviorist ideas, recent studies suggest that introspection can be accurate and reliable. However, an unresolved question is whether people are able to report specific aspects of their phenomenal experience, or whether they report more general nonspecific experiences. To address this question, we investigated the sensitivity and validity of our introspection for different types of conflict. Taking advantage of the congruency sequence effect, we dissociated response conflict while keeping visual conflict unchanged in a Stroop and in a priming task. Participants were subsequently asked to report on either their experience of urge to err or on their feeling of visual conflict. Depending on the focus of the introspection, subjective reports specifically followed either the response conflict or the visual conflict. These results demonstrate that our introspective reports can be sensitive and that we are able to dissociate specific aspects of our phenomenal experiences in a valid manner. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Experimental analysis for fabrication of high-aspect-ratio piezoelectric ceramic structure by micro-powder injection molding process

NASA Astrophysics Data System (ADS)

Han, Jun Sae; Gal, Chang Woo; Park, Jae Man; Kim, Jong Hyun; Park, Seong Jin

2018-04-01

Aspect ratio effects in the micro-powder injection molding process were experimentally analyzed for fabrication of high-aspect-ratio piezoelectric ceramic structure. The mechanisms of critical defects have been studied according to individual manufacturing steps. In the molding process, incomplete filling phenomenon determines the critical aspect ratios of a micro pattern. According to mold temperature, an incomplete filling phenomenon has been analyzed with respect to different pattern sizes and aspect ratio. In demolding and drying process, the capillary behavior of sacrificial polymeric mold insert determines the critical aspect ratio of a micro pattern. With respect to pattern dimensions, slumping behavior has been analyzed. Based on our current systems, micro PZT feature has stability when it has lower aspect ratio than 5. Under optimized processing conditions, 20 μm and 40 μm ceramic rod array feature which has 5 of aspect ratio were successfully fabricated by the developed process. Further modification points to fabricate the smaller and higher feature were specifically addressed.

2 (Secondary) + 2 (Postsecondary) Articulated Curriculum for Health Occupations: A How-To-Manual.

ERIC Educational Resources Information Center

Lovelace, Bill E.; And Others

This manual addresses specific aspects of the development and implementation of articulated vocational programs between high schools and colleges. The approach presented in the manual was derived from research and the experiences of the Paris Junior College (Texas) project staff who developed a "2 + 2" articulated career ladder curriculum for…

A Theoretical Assessment of Regional Development Effects on the Demand for General Education

ERIC Educational Resources Information Center

Iwahashi, Roki

2007-01-01

This study addresses a prospective aspect of general education: through general education, people obtain information about returns to their future specific education, thereby enabling them to choose fields in which they excel. According to that property of education, this paper presents a theoretical framework as a basis for understanding effects…

Reconsidering Learning Difficulties and Misconceptions in Chemistry: Emergence in Chemistry and Its Implications for Chemical Education

ERIC Educational Resources Information Center

Tümay, Halil

2016-01-01

Identifying students' misconceptions and learning difficulties and finding effective ways of addressing them has been one of the major concerns in chemistry education. However, the chemistry education community has paid little attention to determining discipline-specific aspects of chemistry that can lead to learning difficulties and…

75 FR 60867 - Fisheries off West Coast States; Pacific Coast Groundfish Fishery Management Plan; Amendments 20...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... stock assessments and other scientific research carried out by states, NMFS, and academia. The states... public should participate in the Council process to help design these amendments. Comment 11. One... discuss the specifics of the program. These workshops are designed to address all aspects of the trawl...

Gravity related features of plant growth behavior studied with rotating machines

NASA Technical Reports Server (NTRS)

Brown, A. H.

1996-01-01

Research in plant physiology consists mostly of studies on plant growth because almost everything a plant does is done by growing. Most aspects of plant growth are strongly influenced by the earth's gravity vector. Research on those phenomena address scientific questions specifically about how plants use gravity to guide their growth processes.

Posters with an artistic flair.

PubMed

Ellerbee, Susan M

2006-01-01

Posters are a popular medium used in the classroom and at conferences. Most published and Internet resources focus on the technical aspects of poster creation. The artist's perspective has rarely been addressed. The author fills that gap by presenting color theory and a balanced appearance as important elements to be considered. Specific technical and artistic considerations are presented.

Practice Makes Perfect: Engaging Student-Citizens in Politics through Theory and Practice

ERIC Educational Resources Information Center

Csajko, Karen; Lindaman, Kara

2011-01-01

We study one aspect of the relationship between theory and politics, in order to begin to address this issue of political science education--specifically focusing on whether participation in the election process as voting monitors, combined with political science education, can help students better understand politics as democratic engagement. In…

Profiting in Education: Politics, Markets, and the Public Good

ERIC Educational Resources Information Center

Crowley, Christopher B.

2015-01-01

The aim of this dissertation is to explore issues of privatization in teacher education. While other research has sought to address specific aspects of privatization affecting teacher education in the United States, the aim of this dissertation study is to conceptualize the influence and impact of neoliberalism on contemporary trends in teacher…

Serbian: The Serbian Language in Education in Hungary. Regional Dossiers Series

ERIC Educational Resources Information Center

Paulik, Anton, Comp.; Solymosi, Judit, Comp.

2014-01-01

This regional dossier aims at providing a concise description of and basic statistics on minority language education in a specific region of Europe--the territory of Magyarország (Hungary). Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as…

Aspects of Writing and Identity

ERIC Educational Resources Information Center

Correa, Djane Antonucci

2011-01-01

This text is the result of reflections that originated in the discussions of a study group composed of undergraduate and postgraduate students in a language lab at a public university in the interior of the state of Parana, in the south of Brazil. This study specifically addresses some considerations about the connections that can be established…

Addressing Plagiarism in Online Programmes at a Health Sciences University: A Case Study

ERIC Educational Resources Information Center

Ewing, Helen; Anast, Ade; Roehling, Tamara

2016-01-01

Plagiarism continues to be a concern for all educational institutions. To build a solid foundation for high academic standards and best practices at a graduate university, aspects of plagiarism were reviewed to develop better management processes for reducing plagiarism. Specifically, the prevalence of plagiarism and software programmes for…

Impact of scabies in resource-poor communities.

PubMed

Heukelbach, Jorg; Mazigo, Humphrey D; Ugbomoiko, Uade S

2013-04-01

Features of endemic scabies are specific in resource-poor and underprivileged communities, with implications for control measures on the community level. In this review, these special aspects are addressed. Scabies is endemic in many resource-poor communities, with a prevalence of 20% and higher. Transmission is influenced by social attitudes, migration, access to healthcare services, housing conditions, hygiene conditions, and crowding. Endemic scabies occurs with severe infestations, complications, and sequels, mainly in children. Sleep loss as a result of scabies-related itching is common. Complications include secondary infections by group A streptococci and acute poststreptococcal glomerulonephritis. Shame, restriction of leisure activities, and stigmatization are common. Treatment of scabies includes a variety of topical compounds, but control on the community level is not an easy task. As ivermectin kills a variety of other parasites, this oral drug is increasingly used for mass treatment. Intervention should address socioemotional aspects using an integrated approach with professionals from different areas, and the community. Scabies is a neglected disease and needs to be perceived as an important public health problem causing morbidity in many resource-poor communities. Future work on epidemiology, clinical aspects, transmission dynamics, socioeconomic aspects, and sustainable control in resource-poor communities is needed.

Security in the Cache and Forward Architecture for the Next Generation Internet

NASA Astrophysics Data System (ADS)

Hadjichristofi, G. C.; Hadjicostis, C. N.; Raychaudhuri, D.

The future Internet architecture will be comprised predominately of wireless devices. It is evident at this stage that the TCP/IP protocol that was developed decades ago will not properly support the required network functionalities since contemporary communication profiles tend to be data-driven rather than host-based. To address this paradigm shift in data propagation, a next generation architecture has been proposed, the Cache and Forward (CNF) architecture. This research investigates security aspects of this new Internet architecture. More specifically, we discuss content privacy, secure routing, key management and trust management. We identify security weaknesses of this architecture that need to be addressed and we derive security requirements that should guide future research directions. Aspects of the research can be adopted as a step-stone as we build the future Internet.

Aphasia rehabilitation during adolescence: a case report.

PubMed

Laures-Gore, Jacqueline; McCusker, Tiffany; Hartley, Leila L

2017-06-01

Descriptions of speech-language interventions addressing the unique aspects of aphasia in adolescence appear to be nonexistent. The current paper presents the case of a male adolescent who experienced a stroke with resultant aphasia and the speech and language therapy he received. Furthermore, we discuss the issues that are unique to an adolescent with aphasia and how they were addressed with this particular patient. Traditional language and apraxia therapy was provided to this patient with inclusion of technology and academic topics. The patient demonstrated improvements in his speech and language abilities, most notably his reading comprehension and speech production. Age-related issues, including academic needs, group treatment, socialization, adherence/compliance, independence and family involvement, emerged during intervention. Although aphasia therapy for adolescents may be similar in many aspects to selected interventions for adults, it is necessary for the clinician to be mindful of age-related issues throughout the course of therapy. Goals and interventions should be selected based on factors salient to an adolescent as well as the potential long-term impact of therapy. Implications for Research Aphasia and its treatment in adolescence need to be further explored. Academics and technology are important aspects of aphasia treatment in adolescence. Issues specific to adolescence such as socialization, adherence/compliance, and independence are important to address in speech-language therapy.

Planetary Data Workshop, Part 2

NASA Technical Reports Server (NTRS)

1984-01-01

Technical aspects of the Planetary Data System (PDS) are addressed. Methods and tools for maintaining and accessing large, complex sets of data are discussed. The specific software and applications needed for processing imaging and non-imaging science data are reviewed. The need for specific software that provides users with information on the location and geometry of scientific observations is discussed. Computer networks and user interface to the PDS are covered along with Computer hardware available to this data system.

Instrumentation Guidelines for the Advanced National Seismic System

USGS Publications Warehouse

Working Group on Instrumentation, Siting

2008-01-01

This document provides guidelines for the seismic-monitoring instrumentation used by long-term earthquake-monitoring stations that will sense ground motion, digitize and store the resulting signals in a local data acquisition unit, and optionally transmit these digital data. These guidelines are derived from specifications and requirements for data needed to address the nation's emergency response, engineering, and scientific needs as identified in U.S. Geological Survey Circular 1188 (1999). Data needs are discussed in terms of national, regional, and urban scales of monitoring in section 3. Functional performance specifications for instrumentation are introduced in section 4.3 and discussed in detail in section 6 in terms of instrument classes and definitions described in section 5. System aspects and testing recommendations are discussed in sections 7 and 8, respectively. Although U.S. Geological Survey Circular 1188 (1999) recommends that the Advanced National Seismic System (ANSS) include portable instrumentation, performance specifications for this element are not specifically addressed in this document. Nevertheless, these guidelines are largely applicable to portable instrumentation. Volcano monitoring instrumentation is also beyond the scope of this document. Guidance for ANSS structural-response monitoring is discussed briefly herein but details are deferred to the ANSS document by the ANSS Structural Response Monitoring Committee (U.S. Geological Survey, 2005). Aspects of station planning, siting, and installation other than instrumentation are beyond the scope of this document.

Manx Gaelic: The Manx Gaelic Language in Education in the Isle of Man. Regional Dossiers Series

ERIC Educational Resources Information Center

McArdle, Fiona, Comp.; Teare, Robert, Comp.

2016-01-01

This regional dossier aims at providing a concise description of and basic statistics on minority language education in a specific region of Europe--the Isle of Man. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative…

The Home-School Interface in Religious and Moral Formation: The Irish Case

ERIC Educational Resources Information Center

Darmody, Merike; Lyons, Maureen; Smyth, Emer

2016-01-01

With the student body across Europe becoming more diverse, the issue of religious education in schools has come to receive greater attention. In the context of the specific historical and institutional context of the Irish primary educational system, this paper addresses aspects of the religious and moral formation of primary school children. The…

Social and Emotional Pedagogies: Critiquing the New Orthodoxy of Emotion in Classroom Behaviour Management

ERIC Educational Resources Information Center

Gillies, Val

2011-01-01

This paper examines new structured attempts to address and manage emotions in the classroom. Critical analysis focuses on the broad emotional literacy agenda operating within schools, and more specifically the Social and Emotional Aspects of Learning (SEAL) programme. Data are drawn on from an ethnographic study located in Behaviour Support Units…

Youth Policies in the European Union. Structures and Training. Studies No. 7.

ERIC Educational Resources Information Center

Lazos, C. G.

This volume contains three studies that address important and complementary aspects of youth work as it is developing in the Member States of the European Union. Chapter 1, Youth Structures and Policies at National Level, has two parts. The first describes the specific nature of youth policies carried out by the various governments and the…

Independent Public Schools: A Move to Increased Autonomy and Devolution of Decision-Making in Western Australian Public Schools

ERIC Educational Resources Information Center

Trimmer, Karen

2013-01-01

With the increasing diversity in schools and the call for addressing specific regional needs, decentralized regulation of the education system is often proposed as an alternative approach to achieve school improvement. Researchers have often associated experimentation and risk-taking as key aspects of effective educational leadership while…

Effects of Specifically Designed Literacy Stations on the Reading Fluency of Students

ERIC Educational Resources Information Center

English, Christine E.

2013-01-01

Reading fluency is critical in all aspects of school curriculum. Struggling readers fall further behind each year due to the increasing demands of the curriculum. To address this problem, the current study implemented literacy stations for struggling readers in a school in rural Washington State. The purpose of this study was to examine (a)…

"Not in the Middle Ages"?: Alan Garner's "The Owl Service" and the Literature of Adolescence.

ERIC Educational Resources Information Center

Hardwick, Paul

2000-01-01

Discusses connecting with the Middle Ages in adolescent fiction. Discusses how, in "The Owl Service," Garner addresses a relationship between adolescence in the late twentieth century and an aspect of the past--specifically the Middle Ages. Considers how "The Owl Service" is a story energized by myth, concerning the…

"Urban-Rural" Dynamics and Indigenous Urbanization: The Case of Inuit Language Use in Ottawa

ERIC Educational Resources Information Center

Patrick, Donna; Budach, Gabriele

2014-01-01

The establishment of cities in Canada has played a pivotal role in the displacement, dispossession, and marginalization of Indigenous peoples. Yet, more than half of the Indigenous population now resides in cities, and urbanization continues to increase. This paper addresses a specific aspect of Inuit mobility--namely, migration and the dynamic…

Adapting Peer Review to an Online Course: An Exploratory Case Study

ERIC Educational Resources Information Center

Knight, Linda V.; Steinbach, Theresa A.

2011-01-01

With demonstrated benefits to higher level learning, peer review in the classroom has been well researched and popular since at least the 1990s. However, little or no prior studies exist into the peer review process for online courses. Further, we found no prior research specifically addressing the operational aspects of online peer review. This…

The Partnership between Project Management and Organizational Change: Integrating Change Management with Change Leadership

ERIC Educational Resources Information Center

Griffith-Cooper, Barber; King, Karyl

2007-01-01

The nature of project management is change. Even though all knowledge areas in the Project Management Body of Knowledge (PMBOK) are rooted in controlling change, none of these areas specifically addresses the human elements of change. There is a significant distinction between directly controlling change relative to the nonhuman aspects of a…

Information visualization: Beyond traditional engineering

NASA Technical Reports Server (NTRS)

Thomas, James J.

1995-01-01

This presentation addresses a different aspect of the human-computer interface; specifically the human-information interface. This interface will be dominated by an emerging technology called Information Visualization (IV). IV goes beyond the traditional views of computer graphics, CADS, and enables new approaches for engineering. IV specifically must visualize text, documents, sound, images, and video in such a way that the human can rapidly interact with and understand the content structure of information entities. IV is the interactive visual interface between humans and their information resources.

Real-Time Considerations for Rugged Embedded Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tumeo, Antonino; Ceriani, Marco; Palermo, Gianluca

This chapter introduces the characterizing aspects of embedded systems, and discusses the specific features that a designer should address to an embedded system “rugged”, i.e., able to operate reliably in harsh environments. The chapter addresses both the hardware and the less obvious software aspect. After presenting a current list of certifications for ruggedization, the chapters present a case study that focuses on the interaction of the hardware and software layers in reactive real-time system. In particular, it shows how the use of fast FPGA prototyping could provide insights on unexpected factors that influence the performance and thus responsiveness to eventsmore » of a scheduling algorithm for multiprocessor systems that manages both periodic, hard real-time task, and aperiodic tasks. The main lesson is that to make the system “rugged”, a designer should consider these issues by, for example, overprovisioning resources and/or computation capabilities.« less

Does Specific Instruction during Collecting from Several Sources Affect the Quality of the Written Text Product?

ERIC Educational Resources Information Center

Hilbig, Annemarie; Proske, Antje

2014-01-01

Although academic writing is a complex interplay of comprehending and producing text the aspect of collecting information from source texts is hardly addressed in writing research. This study examined the impact of instructions supporting the collection process on writing quality, as well as the role of prior motivation and computer experience.…

DSB Task Force on Cyber Supply Chain

DTIC Science & Technology

2017-04-01

seeking to exploit a maliciously inserted vulnerability must execute each step in the kill chain:  Intelligence and planning: gathering...are intended to take a comprehensive approach in considering all aspects of system security, including cybersecurity , and address initial steps to...specific integrated circuits (ASICs). That need is likely to grow for systems that support intelligent or autonomous capabilities. The current

Domain-Specific Aspects of Technological Pedagogical Content Knowledge: Music Education and the Importance of Affect

ERIC Educational Resources Information Center

Macrides, Elena; Angeli, Charoula

2018-01-01

The present study addresses the lack of a theoretical framework for the integration of technology in music teaching and learning, and explores, within the framework of Technological Pedagogical Content Knowledge (TPACK), the importance of affect in the instructional design of music lessons. The purpose of this study is twofold: (a) to extend the…

Incivility in nursing: the connection between academia and clinical settings.

PubMed

Luparell, Susan

2011-04-01

Incivility and bullying in nursing are complex problems that have garnered much attention in recent years. Emerging evidence suggests that incivility in the workplace has significant implications for nurses, patients, and health care organizations. Because today's students are tomorrow's colleagues, conversations regarding how to address incivility and bullying should include specific aspects of nursing academia and the preparation of new nurses.

The American Indian Reader: History. Book Four of a Series in Educational Perspectives.

ERIC Educational Resources Information Center

Costo, Rupert; Henry, Jeannette, Ed.

In an attempt to rewrite American history incorporating "long hidden facts" pertinent to the American Indian, this book endeavors to relate the "truth in history" and make "humanity see itself face to face without fear and in spite of the pangs of conscience". Each of 7 chapters addresses a specific aspect of American history relevant to the…

Multivariate time series analysis of neuroscience data: some challenges and opportunities.

PubMed

Pourahmadi, Mohsen; Noorbaloochi, Siamak

2016-04-01

Neuroimaging data may be viewed as high-dimensional multivariate time series, and analyzed using techniques from regression analysis, time series analysis and spatiotemporal analysis. We discuss issues related to data quality, model specification, estimation, interpretation, dimensionality and causality. Some recent research areas addressing aspects of some recurring challenges are introduced. Copyright © 2015 Elsevier Ltd. All rights reserved.

Quality of Care Measures for the Management of Unhealthy Alcohol Use

PubMed Central

Hepner, Kimberly A.; Watkins, Katherine E.; Farmer, Carrie M.; Rubenstein, Lisa; Pedersen, Eric R.; Pincus, Harold Alan

2017-01-01

There is a paucity of quality measures to assess the care for the range of unhealthy alcohol use, ranging from risky drinking to alcohol use disorders. Using a two-phase expert panel review process, we sought to develop an expanded set of quality of care measures for unhealthy alcohol use, focusing on outpatient care delivered in both primary care and specialty care settings. This process generated 25 candidate measures. Eight measures address screening and assessment, 11 address aspects of treatment, and six address follow-up. These quality measures represent high priority targets for future development, including creating detailed technical specifications and pilot testing them to evaluate their utility in terms of feasibility, reliability, and validity. PMID:28340902

Design of the environment of care for safety of patients and personnel: does form follow function or vice versa in the intensive care unit?

PubMed

Bartley, Judene; Streifel, Andrew J

2010-08-01

We review the context of the environment of care in the intensive care unit setting in relation to patient safety and quality, specifically addressing healthcare-associated infection issues and solutions involving interdisciplinary teams. Issues addressed include current and future architectural design and layout trends, construction trends affecting intensive care units, and prevention of construction-associated healthcare-associated infections related to airborne and waterborne risks and design solutions. Specific elements include single-occupancy, acuity-scalable intensive care unit rooms; environmental aspects of hand hygiene, such as water risks, sink design/location, human waste management, surface selection (floor covering, countertops, furniture, and equipment) and cleaning, antimicrobial-treated or similar materials, ultraviolet germicidal irradiation, specialized rooms (airborne infection isolation and protective environments), and water system design and strategies for safe use of potable water and mitigation of water intrusion. Effective design and operational use of the intensive care unit environment of care must engage critical care personnel from initial planning and design through occupancy of the new/renovated intensive care unit as part of the infection control risk assessment team. The interdisciplinary infection control risk assessment team can address key environment of care design features to enhance the safety of intensive care unit patients, personnel, and visitors. This perspective will ensure the environment of care supports human factors and behavioral aspects of the interaction between the environment of care and its occupants.

Aesthetic strategies for the aging Asian face.

PubMed

Lam, Samuel M

2007-08-01

Aging that manifests in the Asian face is remarkably different, yet in many ways similar, to that of the white face. These dissimilarities and similarities are highlighted in this article along with overall strategies to approach the aging Asian face. This article focuses almost exclusively on the judgment and thinking that are required when approaching the Asian patient. More specifically, one issue that is covered is the cultural aspect that pertains to patient motivation and perspectives on cosmetic enhancement. The other equally important aspect that is addressed is elaboration of a new paradigm on what constitutes a youthful face, especially as that model relates to the Asian face.

Essentials of oral cancer

PubMed Central

Rivera, César

2015-01-01

Oral cancer is one of the 10 most common cancers in the world, with a delayed clinical detection, poor prognosis, without specific biomarkers for the disease and expensive therapeutic alternatives. This review aims to present the fundamental aspects of this cancer, focused on squamous cell carcinoma of the oral cavity (OSCC), moving from its definition and epidemiological aspects, addressing the oral carcinogenesis, oral potentially malignant disorders, epithelial precursor lesions and experimental methods for its study, therapies and future challenges. Oral cancer is a preventable disease, risk factors and natural history is already being known, where biomedical sciences and dentistry in particular are likely to improve their poor clinical indicators. PMID:26617944

Essentials of oral cancer.

PubMed

Rivera, César

2015-01-01

Oral cancer is one of the 10 most common cancers in the world, with a delayed clinical detection, poor prognosis, without specific biomarkers for the disease and expensive therapeutic alternatives. This review aims to present the fundamental aspects of this cancer, focused on squamous cell carcinoma of the oral cavity (OSCC), moving from its definition and epidemiological aspects, addressing the oral carcinogenesis, oral potentially malignant disorders, epithelial precursor lesions and experimental methods for its study, therapies and future challenges. Oral cancer is a preventable disease, risk factors and natural history is already being known, where biomedical sciences and dentistry in particular are likely to improve their poor clinical indicators.

Psychology and the Rationality of Emotion.

PubMed

Clore, Gerald L

2011-04-01

Questions addressed by recent psychological research on emotion include questions about how thought shapes emotion and how emotion, in turn, shapes thought. Research on emotion and cognition paints a somewhat different picture than that seen in traditional discussions of passion and reason. This article reviews several aspects of this research, concentrating specifically on three views of rationality: Rationality as Process, Rationality as Product, and Rationality as Outcome.

Psychology and the Rationality of Emotion*

PubMed Central

Clore, Gerald L.

2014-01-01

Questions addressed by recent psychological research on emotion include questions about how thought shapes emotion and how emotion, in turn, shapes thought. Research on emotion and cognition paints a somewhat different picture than that seen in traditional discussions of passion and reason. This article reviews several aspects of this research, concentrating specifically on three views of rationality: Rationality as Process, Rationality as Product, and Rationality as Outcome. PMID:25125770

Addressing the Professional Development Needs of Teachers Working in the Area of Special Education/Inclusion in Mainstream Schools in Ireland

ERIC Educational Resources Information Center

O'Gorman, Elizabeth; Drudy, Sheelagh

2010-01-01

This paper gives an account of one aspect of a recent research project that explored dimensions of inclusion in mainstream schools in Ireland. In particular, the working lives of teachers who have specific responsibility for students with disabilities and/or special educational needs (SEN) in mainstream schools were explored. In Ireland, such…

A Study of Placing Army Requirements on Contract

DTIC Science & Technology

2016-04-01

perhaps being unable to control the external environment, has management authority over business and technical aspects of a specific program. The PM...research is the last element of the planning phase addressing both business and technical considerations. The acquisition team equips themselves with...report is the final product utilizing documented findings and supports the business strategy (DoD, Guidebook for the Acquisition of Services, 2011

Invited Paper Thin Film Technology In Design And Production Of Optical Systems

NASA Astrophysics Data System (ADS)

Guenther, K. H.; Menningen, R.; Burke, C. A.

1983-10-01

Basic optical properties of dielectric thin films for interference applications and of metallic optical coatings are reviewed. Some design considerations of how to use thin films best in optical systems are given, and some aspects of thin film production technology relevant to the optical designer and the optician are addressed. The necessity of proper specifications, inclusive of test methods, is emphasized.

Guide d'enseignement du francais au secondaire. Volet I: Comprehension ecrite. Immersion (Teaching Guide for French at the Secondary Level. Part I: Reading Comprehension. Immersion).

ERIC Educational Resources Information Center

Leduc, Denise

This guide to secondary school French reading instruction addresses a variety of general and specific instructional issues. An introductory chapter discusses program objectives, minimum program requirements, and the population to be taught. The second chapter looks at theoretical aspects of the development of reading ability: current thoughts on…

Organizational context and taxonomy of health care databases.

PubMed

Shatin, D

2001-01-01

An understanding of the organizational context and taxonomy of health care databases is essential to appropriately use these data sources for research purposes. Characteristics of the organizational structure of the specific health care setting, including the model type, financial arrangement, and provider access, have implications for accessing and using this data effectively. Additionally, the benefit coverage environment may affect the utility of health care databases to address specific research questions. Coverage considerations that affect pharmacoepidemiologic research include eligibility, the nature of the pharmacy benefit, and regulatory aspects of the treatment under consideration.

Jet Fuel Thermal Stability

NASA Technical Reports Server (NTRS)

Taylor, W. F. (Editor)

1979-01-01

Various aspects of the thermal stability problem associated with the use of broadened-specification and nonpetroleum-derived turbine fuels are addressed. The state of the art is reviewed and the status of the research being conducted at various laboratories is presented. Discussions among representatives from universities, refineries, engine and airframe manufacturers, airlines, the Government, and others are presented along with conclusions and both broad and specific recommendations for future stability research and development. It is concluded that significant additional effort is required to cope with the fuel stability problems which will be associated with the potentially poorer quality fuels of the future such as broadened specification petroleum fuels or fuels produced from synthetic sources.

Some aspects of doping and medication control in equine sports.

PubMed

Houghton, Ed; Maynard, Steve

2010-01-01

This chapter reviews drug and medication control in equestrian sports and addresses the rules of racing, the technological advances that have been made in drug detection and the importance of metabolism studies in the development of effective drug surveillance programmes. Typical approaches to screening and confirmatory analysis are discussed, as are the quality processes that underpin these procedures. The chapter also addresses four specific topics relevant to equestrian sports: substances controlled by threshold values, the approach adopted recently by European racing authorities to control some therapeutic substances, anabolic steroids in the horse and LC-MS analysis in drug testing in animal sports and metabolism studies. The purpose of discussing these specific topics is to emphasise the importance of research and development and collaboration to further global harmonisation and the development and support of international rules.

Publications - USGS Publications Series | Alaska Division of Geological &

Science.gov Websites

different aspects of a single scientific topic, either issued as individual chapters or as a single volume related papers addressing different aspects of a single scientific topic, either issued together under one illustrations. The series also may include collections of related maps addressing different aspects of a single

Skincare Bootcamp: The Evolving Role of Skincare.

PubMed

Rodan, Katie; Fields, Kathy; Majewski, George; Falla, Timothy

2016-12-01

Although cosmetic procedures have a significant impact on certain aspects of aging, such as deep, wrinkling, sagging, and volume loss, they fail to address the overall quality of the skin. Daily skincare routines potentially can have a significant long-term impact on the overall quality of a person's complexion. By expanding our product knowledge, we can help our patients individualize their at-home skincare routine using effective products and ingredients designed to address their specific skin concern and support the professional care we deliver. Here, we discuss the types of products and ingredients suitable for the most common dermatologic concerns, from wrinkling to skin sensitivity, acne to sun damage.

Fluoride mechanisms.

PubMed

ten Cate, J M; van Loveren, C

1999-10-01

This article discusses fluoride mechanisms in relation to dental caries. The authors specifically address firmly bound versus loosely bound fluoride; different fluoride active ingredients; fluoride and demineralization and remineralization; fluoride slow-release devices and F-releasing dental materials; antimicrobial effects of fluoride; the uptake of fluoride by oral bacteria; inhibition of enolase, protein-intruding ATPase and sugar transport; the various aspects of plaque as it relates to fluoride; and the rational use of fluoride.

IHE based interoperability - benefits and challenges.

PubMed

Wozak, Florian; Ammenwerth, Elske; Hörbst, Alexander; Sögner, Peter; Mair, Richard; Schabetsberger, Thomas

2008-01-01

Optimized workflows and communication between institutions involved in a patient's treatment process can lead to improved quality and efficiency in the healthcare sector. Electronic Health Records (EHRs) provide a patient-centered access to clinical data across institutional boundaries supporting the above mentioned aspects. Interoperability is regarded as vital success factor. However a clear definition of interoperability does not exist. The aim of this work is to define and to assess interoperability criteria as required for EHRs. The definition and assessment of interoperability criteria is supported by the analysis of existing literature and personal experience as well as by discussions with several domain experts. Criteria for interoperability addresses the following aspects: Interfaces, Semantics, Legal and organizational aspects and Security. The Integrating the Healthcare Enterprises initiative (IHE) profiles make a major contribution to these aspects, but they also arise new problems. Flexibility for adoption to different organizational/regional or other specific conditions is missing. Regional or national initiatives should get a possibility to realize their specific needs within the boundaries of IHE profiles. Security so far is an optional element which is one of IHE greatest omissions. An integrated security approach seems to be preferable. Irrespective of the so far practical significance of the IHE profiles it appears to be of great importance, that the profiles are constantly checked against practical experiences and are continuously adapted.

Night work and the reproductive health of women: an integrated literature review.

PubMed

Chau, Yu Moon; West, Sandra; Mapedzahama, Virginia

2014-01-01

The aim of this review was to synthesize current evidence on the effects of night work on the major stages of women's reproductive health, specifically the menstrual cycle, fertility, pregnancy, and menopause. Current understanding suggests that night work (work that causes disruption of a worker's circadian [day/night] rhythms) adversely affects workers' health and well-being. A complex relationship exists between circadian rhythms and reproductive hormones, and this may potentially increase the vulnerability of women to the detrimental effect of night work, including during menopause. A systematic search was conducted (March-May 2011) via CINAHL, MEDLINE, Sociological Abstracts, and Business Source Premier for primary research studies written in English using the key words "shift-work" and "female/women." Findings of identified articles were themed to pregnancy, fertility, aspects of menstrual cycles, and menopause. Twenty articles were identified, (13 articles concerning pregnancy, 3 addressing fertility, and 4 addressing aspects of the menstrual cycle) but no studies addressing menopause were located. All identified articles demonstrated problematic approaches to the determination of night-work exposure. Evidence of the impact of night work on female reproductive health as presented in the current literature is inconclusive. Moreover, available evidence needs to be interpreted with caution, given the various limitations and inconsistencies among the studies in the measurement of night-work exposure and shift-work patterns. Studies that focus specifically on night work are needed to facilitate an understanding of the impact of circadian disruption on the reproductive health of women undertaking night work. © 2013 by the American College of Nurse-Midwives.

Technical analysis of US Army Weapons Systems and related advanced technologies of military interest. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1991-06-14

This report summarizes the activities and accomplishments of an US Army technology security project designed to identify and develop effective policy guidelines for militarily critical technologies in specific Army systems and in broad generic technology areas of military interest, Individual systems analyses are documented in separate Weapons Systems Technical Assessments (WSTAs) and the general generic technology areas are evaluated in the Advanced Technology Assessment Reports (ATARs), However, specific details of these assessments are not addressed here, only recommendations regarding aspects of the defined approach, methodology, and format are provided and discussed.

Women with epilepsy: clinically relevant issues

PubMed Central

Bangar, Santosh; Shastri, Abhishek; El-Sayeh, Hany; Cavanna, Andrea E.

2016-01-01

Summary Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects. Awareness of these gender-specific issues and implementation/adaptation of effective interventions for WWE results in significantly improved health-related quality of life in this patient population. PMID:27678205

A modified tensionless gingival grafting technique using acellular dermal matrix.

PubMed

Taylor, John B; Gerlach, Robert C; Herold, Robert W; Bisch, Frederick C; Dixon, Douglas R

2010-10-01

Conventional surgical procedures designed for autogenous tissue material may not be appropriate when using acellular dermal matrix (ADM) for the treatment of gingival recessions. This article describes a new surgical technique that addresses the unique and sensitive aspects of ADM specifically to improve esthetic outcomes and gain increased clinical predictability when treating Miller Class I and II gingival recession defects. In this paper, a root coverage case is described and the specific steps and rationale for this new technique are explained. This technique has been predictable clinically, with results comparable to those achieved using autogenous tissue.

Effective domain-dependent reuse in medical knowledge bases.

PubMed

Dojat, M; Pachet, F

1995-12-01

Knowledge reuse is now a critical issue for most developers of medical knowledge-based systems. As a rule, reuse is addressed from an ambitious, knowledge-engineering perspective that focuses on reusable general purpose knowledge modules, concepts, and methods. However, such a general goal fails to take into account the specific aspects of medical practice. From the point of view of the knowledge engineer, whose goal is to capture the specific features and intricacies of a given domain, this approach addresses the wrong level of generality. In this paper, we adopt a more pragmatic viewpoint, introducing the less ambitious goal of "domain-dependent limited reuse" and suggesting effective means of achieving it in practice. In a knowledge representation framework combining objects and production rules, we propose three mechanisms emerging from the combination of object-oriented programming and rule-based programming. We show these mechanisms contribute to achieve limited reuse and to introduce useful limited variations in medical expertise.

Clinical supervision of psychotherapy: essential ethics issues for supervisors and supervisees.

PubMed

Barnett, Jeffrey E; Molzon, Corey H

2014-11-01

Clinical supervision is an essential aspect of every mental health professional's training. The importance of ensuring that supervision is provided competently, ethically, and legally is explained. The elements of the ethical practice of supervision are described and explained. Specific issues addressed include informed consent and the supervision contract, supervisor and supervisee competence, attention to issues of diversity and multicultural competence, boundaries and multiple relationships in the supervision relationship, documentation and record keeping by both supervisor and supervisee, evaluation and feedback, self-care and the ongoing promotion of wellness, emergency coverage, and the ending of the supervision relationship. Additionally, the role of clinical supervisor as mentor, professional role model, and gatekeeper for the profession are discussed. Specific recommendations are provided for ethically and effectively conducting the supervision relationship and for addressing commonly arising dilemmas that supervisors and supervisees may confront. © 2014 Wiley Periodicals, Inc.

Guidelines for the Clinical Use of Electronic Mail with Patients

PubMed Central

Kane, Beverley; Sands, Daniel Z.

1998-01-01

Guidelines regarding patient—provider electronic mail are presented. The intent is to provide guidance concerning computer-based communications between clinicians and patients within a contractual relationship in which the health-care provider has taken on an explicit measure of responsibility for the client's care. The guidelines address two interrelated aspects: effective interaction between the clinician and patient, and observance of medicolegal prudence. Recommendations for site-specific policy formulation are included. PMID:9452989

Federal Laws Relating to Cybersecurity: Overview and Discussion of Proposed Revisions

DTIC Science & Technology

2013-06-20

originally introduced in March.19 Several other Senate bills would have addressed specific aspects of cybersecurity, such as data breaches of personal...H.R. 3674)c X X X Public awareness H.R. 756 X X X X Cybercrime law X X X Data breach notification X X Internet security...Revisions Congressional Research Service 20 Data Breach Notification. The White House Proposal and the Task Force Report would also both have set

Skincare Bootcamp: The Evolving Role of Skincare

PubMed Central

Rodan, Katie; Fields, Kathy; Majewski, George

2016-01-01

Background: Although cosmetic procedures have a significant impact on certain aspects of aging, such as deep, wrinkling, sagging, and volume loss, they fail to address the overall quality of the skin. Methods: Daily skincare routines potentially can have a significant long-term impact on the overall quality of a person’s complexion. Results: By expanding our product knowledge, we can help our patients individualize their at-home skincare routine using effective products and ingredients designed to address their specific skin concern and support the professional care we deliver. Conclusions: Here, we discuss the types of products and ingredients suitable for the most common dermatologic concerns, from wrinkling to skin sensitivity, acne to sun damage. PMID:28018771

Patient evaluation in idiopathic scoliosis: Radiographic assessment, trunk deformity and back asymmetry.

PubMed

Rigo, Manuel

2011-01-01

Progressive adolescent idiopathic scoliosis (AIS) produces specific signs and symptoms, including trunk and spinal deformity and imbalance, impairment of breathing function, pain, progression during adult life, and psychological problems, as a whole resulting in an alteration of the health-related quality of life. A scoliosis-specific rehabilitation program attempts to prevent, improve, or minimize these signs and symptoms by using exercises and braces as the main tools in the rehabilitation treatment. Patient evaluation is an essential point in the decision-making process and determines the selection of the specific exercises and the specifications of the brace design. However, this article is not addressed to scoliosis management. In this present article, a complete definition and discussion of radiological aspects, such as the Cobb angle, axial rotation, curve pattern classifications, and sagittal configuration, follow a short description of the three-dimensional nature of AIS. The relationship between AIS and growth is also discussed. There is also a section dedicated to the assessment of trunk deformity and back asymmetry. Other important clinical aspects, such as pain and disability, changes in other regions of the body, muscular balance, breathing function, and health-related quality of life, are not discussed in this present article.

A user-targeted synthesis of the VALUE perfect predictor experiment

NASA Astrophysics Data System (ADS)

Maraun, Douglas; Widmann, Martin; Gutierrez, Jose; Kotlarski, Sven; Hertig, Elke; Wibig, Joanna; Rössler, Ole; Huth, Radan

2016-04-01

VALUE is an open European network to validate and compare downscaling methods for climate change research. A key deliverable of VALUE is the development of a systematic validation framework to enable the assessment and comparison of both dynamical and statistical downscaling methods. VALUE's main approach to validation is user-focused: starting from a specific user problem, a validation tree guides the selection of relevant validation indices and performance measures. We consider different aspects: (1) marginal aspects such as mean, variance and extremes; (2) temporal aspects such as spell length characteristics; (3) spatial aspects such as the de-correlation length of precipitation extremes; and multi-variate aspects such as the interplay of temperature and precipitation or scale-interactions. Several experiments have been designed to isolate specific points in the downscaling procedure where problems may occur. Experiment 1 (perfect predictors): what is the isolated downscaling skill? How do statistical and dynamical methods compare? How do methods perform at different spatial scales? Experiment 2 (Global climate model predictors): how is the overall representation of regional climate, including errors inherited from global climate models? Experiment 3 (pseudo reality): do methods fail in representing regional climate change? Here, we present a user-targeted synthesis of the results of the first VALUE experiment. In this experiment, downscaling methods are driven with ERA-Interim reanalysis data to eliminate global climate model errors, over the period 1979-2008. As reference data we use, depending on the question addressed, (1) observations from 86 meteorological stations distributed across Europe; (2) gridded observations at the corresponding 86 locations or (3) gridded spatially extended observations for selected European regions. With more than 40 contributing methods, this study is the most comprehensive downscaling inter-comparison project so far. The results clearly indicate that for several aspects, the downscaling skill varies considerably between different methods. For specific purposes, some methods can therefore clearly be excluded.

Thin-film module circuit design: Practical and reliability aspects

NASA Technical Reports Server (NTRS)

Daiello, R. V.; Twesme, E. N.

1985-01-01

This paper will address several aspects of the design and construction of submodules based on thin film amorphous silicon (a-Si) p i n solar cells. Starting from presently attainable single cell characteristics, and a realistic set of specifications, practical module designs are discussed from the viewpoints of efficient designs, the fabrication requirements, and reliability concerns. The examples center mostly on series interconnected modules of the superstrate type with detailed discussions of each portion of the structure in relation to its influence on module efficiency. Emphasis is placed on engineering topics such as: area coverage, optimal geometries, and cost and reliability. Practical constraints on achieving optimal designs, along with some examples of potential pitfalls in the manufacture and subsequent performance of a-Si modules are discussed.

Telomerase and the search for the end of cancer.

PubMed

Mocellin, Simone; Pooley, Karen A; Nitti, Donato

2013-02-01

Many of the fundamental molecular mechanisms underlying tumor biology remain elusive and, thus, developing specific anticancer therapies remains a challenge. The recently discovered relationships identified among telomeres, telomerase, aging, and cancer have opened a new avenue in tumor biology research that may revolutionize anticancer therapy. This review summarizes the critical aspects of telomerase biology that underpin the development of novel telomerase-targeting therapies for malignant diseases, and special regard is given to the aspects of telomerase that make it such an appealing target, such as the widespread expression of telomerase in cancers. Despite significant progress, issues remain to be addressed before telomerase-based therapies are truly effective and we include critical discussion of the results obtained thus far. Copyright © 2012 Elsevier Ltd. All rights reserved.

The autonomy of biological individuals and artificial models.

PubMed

Moreno, Alvaro; Etxeberria, Arantza; Umerez, Jon

2008-02-01

This paper aims to offer an overview of the meaning of autonomy for biological individuals and artificial models rooted in a specific perspective that pays attention to the historical and structural aspects of its origins and evolution. Taking autopoiesis and the recursivity characteristic of its circular logic as a starting point, we depart from some of its consequences to claim that the theory of autonomy should also take into account historical and structural features. Autonomy should not be considered only in internal or constitutive terms, the largely neglected interactive aspects stemming from it should be equally addressed. Artificial models contribute to get a better understanding of the role of autonomy for life and the varieties of its organization and phenomenological diversity.

Planning, Managing, and Financing in the 1980s. Achieving Excellence, Diversity, and Access in the Context of Stable Resources and Demands for Increased Productivity. Proceedings of the 1977 NCHEMS National Assembly (Denver, Colorado, November 6-8, 1977).

ERIC Educational Resources Information Center

Western Interstate Commission for Higher Education, Boulder, CO. National Center for Higher Education Management Systems.

The 1977 National Assembly of the National Center for Higher Education Management Systems addressed specific aspects of excellence, diversity, and access to postsecondary education and suggested ways to preserve these values in planning, managing, and financing in the 1980's. The following conference papers are presented: "Placing Value…

Integration of Department of Defense and State Department Efforts to Continue the Global Pursuit of Violent Extremist Organizations

DTIC Science & Technology

2012-12-14

structure to take on intelligence collection and fusion, the State Department has historically not been a collector of intelligence as a matter of...Government, specifically the CIA and NSA, but their mission, structure and capability will not be addressed in this thesis. It is understood, though...provided firsthand accounts of aspects of DoD and State Department coordination or provided the necessary information about current structure and

System design projects for undergraduate design education

NASA Technical Reports Server (NTRS)

Batill, S. M.; Pinkelman, J.

1993-01-01

Design education has received considerable in the recent past. This paper is intended to address one aspect of undergraduate design education and that is the selection and development of the design project for a capstone design course. Specific goals for a capstone design course are presented and their influence on the project selection are discussed. The evolution of a series of projects based upon the design of remotely piloted aircraft is presented along with students' perspective on the capstone experience.

Computational models of music perception and cognition II: Domain-specific music processing

NASA Astrophysics Data System (ADS)

Purwins, Hendrik; Grachten, Maarten; Herrera, Perfecto; Hazan, Amaury; Marxer, Ricard; Serra, Xavier

2008-09-01

In Part I [Purwins H, Herrera P, Grachten M, Hazan A, Marxer R, Serra X. Computational models of music perception and cognition I: The perceptual and cognitive processing chain. Physics of Life Reviews 2008, in press, doi:10.1016/j.plrev.2008.03.004], we addressed the study of cognitive processes that underlie auditory perception of music, and their neural correlates. The aim of the present paper is to summarize empirical findings from music cognition research that are relevant to three prominent music theoretic domains: rhythm, melody, and tonality. Attention is paid to how cognitive processes like category formation, stimulus grouping, and expectation can account for the music theoretic key concepts in these domains, such as beat, meter, voice, consonance. We give an overview of computational models that have been proposed in the literature for a variety of music processing tasks related to rhythm, melody, and tonality. Although the present state-of-the-art in computational modeling of music cognition definitely provides valuable resources for testing specific hypotheses and theories, we observe the need for models that integrate the various aspects of music perception and cognition into a single framework. Such models should be able to account for aspects that until now have only rarely been addressed in computational models of music cognition, like the active nature of perception and the development of cognitive capacities from infancy to adulthood.

Integrating psychopharmacology and cognitive remediation to treat cognitive dysfunction in the psychotic disorders.

PubMed

Medalia, Alice; Opler, Lewis A; Saperstein, Alice M

2014-04-01

Cognitive deficits are a prominent and enduring aspect of schizophrenia, which pose a significant barrier to achieving functional goals. The most promising intervention for treating cognitive impairment is cognitive remediation (CR), a behaviorally based therapy associated with medium effect sizes for cognitive and functional outcomes. However, there is a sizeable group of nonresponders whose CR outcomes become limited when the therapeutic approach fails to address individual differences in baseline cognition, motivation variables, and the extent to which CR offers opportunities for generalization. This speaks to a need to develop cognitive interventions that are both personalized and scalable. Emerging data suggest that specific pharmacological agents have the potential to enhance and accelerate behaviorally based CR effects. This article will review the rationale and preliminary evidence to support combining CR and pharmacotherapy. We will review crucial aspects of cognitive interventions that offer the most promise for improving not only cognitive outcomes, but also for enhancing improvement in real-world functioning. Finally, we will address methodological issues to be considered for future research on combined pharmacological and CR interventions.

Treating patients with bipolar disorder and substance dependence: lessons learned.

PubMed

Weiss, Roger D

2004-12-01

Although bipolar disorder is the Axis I psychiatric disorder associated with the highest rate of co-occurring substance use disorders, little research has focused on treatments specifically designed for these patients. The author and his colleagues have developed and studied Integrated Group Therapy (IGT) for this population. This paper describes common themes that have emerged in carrying out IGT for patients with bipolar disorder and substance dependence. These include the strong emphasis on depression, as opposed to mania; the predominance of hopelessness; specific patterns of medication noncompliance; and the implications of patients' labeling their substance use as self-medication. Therapeutic aspects involved in addressing these themes are discussed.

Multi-Criteria Analysis of Uavs Regulations in 6 Countries Using the Analytical Hierarchical Process and Expert Knowledge

NASA Astrophysics Data System (ADS)

Morales, A. C.; Paez, D.; Arango, C.

2015-08-01

To analyze the current situation of Colombian regulation, it is necessary to compare some specific aspects with the legislation used in other countries where the UAVs topic dates to many years ago. This study is focused on evaluating all the possibilities to make the Colombian regulation effective without closing opportunities of research and development growth, but still guarantee the privacy and intimacy rights of the population. Results from our study are currently being used in the development of the Colombian regulation and they are proven useful to instigate informative debates and identify areas where specific needs are to be address in Colombia.

Language processing and forms of immediate echolalia in autistic children.

PubMed

Paccia, J M; Curcio, F

1982-03-01

Several aspects of echolalic speech produced by five autistic children were investigated. We found that the incidence of echolalia was influenced by the type of question addressed to the child and, to a lesser extent, by the child's comprehension of the specific relationships expressed in the question. Additionally, acoustic analysis showed that a substantial proportion of echoes involved a prosodic modification of the examiner's question. Further analyses indicated that some of these modified echoes represent more than just a primitive conversational strategy. Specifically, they seem to reflect a higher level of processing and serve a semantic function, that of affirming the examiner's question.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hart, Darren M.

Sandia National Laboratories has tested and evaluated Geotech Smart24 data acquisition system with active Fortezza crypto card data signing and authentication. The test results included in this report were in response to static and tonal-dynamic input signals. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and 1241 for Analog to Digital Converters; others were designed by Sandia specifically for infrasound application evaluation and for supplementary criteria not addressed in the IEEE standards. The objective of this work was to evaluate the overall technical performance of the Geotech Smart24 digitizer with a Fortezza PCMCIA cryptomore » card actively implementing the signing of data packets. The results of this evaluation were compared to relevant specifications provided within manufacturer's documentation notes. The tests performed were chosen to demonstrate different performance aspects of the digitizer under test. The performance aspects tested include determining noise floor, least significant bit (LSB), dynamic range, cross-talk, relative channel-to-channel timing, time-tag accuracy, analog bandwidth and calibrator performance.« less

Hispanic women overcoming deterrents to computer science: A phenomenological study

NASA Astrophysics Data System (ADS)

Herling, Lourdes

The products of computer science are important to all aspects of society and are tools in the solution of the world's problems. It is, therefore, troubling that the United States faces a shortage in qualified graduates in computer science. The number of women and minorities in computer science is significantly lower than the percentage of the U.S. population which they represent. The overall enrollment in computer science programs has continued to decline with the enrollment of women declining at a higher rate than that of men. This study addressed three aspects of underrepresentation about which there has been little previous research: addressing computing disciplines specifically rather than embedding them within the STEM disciplines, what attracts women and minorities to computer science, and addressing the issues of race/ethnicity and gender in conjunction rather than in isolation. Since women of underrepresented ethnicities are more severely underrepresented than women in general, it is important to consider whether race and ethnicity play a role in addition to gender as has been suggested by previous research. Therefore, this study examined what attracted Hispanic women to computer science specifically. The study determines whether being subjected to multiple marginalizations---female and Hispanic---played a role in the experiences of Hispanic women currently in computer science. The study found five emergent themes within the experiences of Hispanic women in computer science. Encouragement and role models strongly influenced not only the participants' choice to major in the field, but to persist as well. Most of the participants experienced a negative atmosphere and feelings of not fitting in while in college and industry. The interdisciplinary nature of computer science was the most common aspect that attracted the participants to computer science. The aptitudes participants commonly believed are needed for success in computer science are the Twenty-First Century skills problem solving, creativity, and critical thinking. While not all the participants had experience with computers or programming prior to attending college, experience played a role in the self-confidence of those who did.

Technical considerations in the psychotherapy of traumatized individuals: a psychoanalytic perspective.

PubMed

Nayar, Monisha C

2008-03-01

This paper addresses two specific aspects of clinical technique in the treatment of traumatized individuals. The first aspect involves the creation of a safe holding environment as an essential step for the emergence of trauma-related memories and the containment of the affects accompanying them. Such scenarios may appear in the clinical material only through the workings of "procedural memory." It is therefore important to contain and gradually decipher repetitive patterns of behavior and feelings of shame, guilt and rage that go with them. The second aspect examines the challenges such work poses to the analyst's containing capacities, credulousness and even his or her reality testing within a clinical situation. The resulting instability of the analyst's work ego can make it hard for him or her to remain vigilant yet empathic, and emotionally attuned but analytically skeptical. The analyst's flexibility to be utilized as a transference object, developmental object and self-object remains a critical determinant of the treatment outcome under such circumstances. The paper provides clinical material to illustrate these two aspects of clinical technique.

Evaluating Health Information Systems Using Ontologies

PubMed Central

Anderberg, Peter; Larsson, Tobias C; Fricker, Samuel A; Berglund, Johan

2016-01-01

Background There are several frameworks that attempt to address the challenges of evaluation of health information systems by offering models, methods, and guidelines about what to evaluate, how to evaluate, and how to report the evaluation results. Model-based evaluation frameworks usually suggest universally applicable evaluation aspects but do not consider case-specific aspects. On the other hand, evaluation frameworks that are case specific, by eliciting user requirements, limit their output to the evaluation aspects suggested by the users in the early phases of system development. In addition, these case-specific approaches extract different sets of evaluation aspects from each case, making it challenging to collectively compare, unify, or aggregate the evaluation of a set of heterogeneous health information systems. Objectives The aim of this paper is to find a method capable of suggesting evaluation aspects for a set of one or more health information systems—whether similar or heterogeneous—by organizing, unifying, and aggregating the quality attributes extracted from those systems and from an external evaluation framework. Methods On the basis of the available literature in semantic networks and ontologies, a method (called Unified eValuation using Ontology; UVON) was developed that can organize, unify, and aggregate the quality attributes of several health information systems into a tree-style ontology structure. The method was extended to integrate its generated ontology with the evaluation aspects suggested by model-based evaluation frameworks. An approach was developed to extract evaluation aspects from the ontology that also considers evaluation case practicalities such as the maximum number of evaluation aspects to be measured or their required degree of specificity. The method was applied and tested in Future Internet Social and Technological Alignment Research (FI-STAR), a project of 7 cloud-based eHealth applications that were developed and deployed across European Union countries. Results The relevance of the evaluation aspects created by the UVON method for the FI-STAR project was validated by the corresponding stakeholders of each case. These evaluation aspects were extracted from a UVON-generated ontology structure that reflects both the internally declared required quality attributes in the 7 eHealth applications of the FI-STAR project and the evaluation aspects recommended by the Model for ASsessment of Telemedicine applications (MAST) evaluation framework. The extracted evaluation aspects were used to create questionnaires (for the corresponding patients and health professionals) to evaluate each individual case and the whole of the FI-STAR project. Conclusions The UVON method can provide a relevant set of evaluation aspects for a heterogeneous set of health information systems by organizing, unifying, and aggregating the quality attributes through ontological structures. Those quality attributes can be either suggested by evaluation models or elicited from the stakeholders of those systems in the form of system requirements. The method continues to be systematic, context sensitive, and relevant across a heterogeneous set of health information systems. PMID:27311735

Evaluating Health Information Systems Using Ontologies.

PubMed

Eivazzadeh, Shahryar; Anderberg, Peter; Larsson, Tobias C; Fricker, Samuel A; Berglund, Johan

2016-06-16

There are several frameworks that attempt to address the challenges of evaluation of health information systems by offering models, methods, and guidelines about what to evaluate, how to evaluate, and how to report the evaluation results. Model-based evaluation frameworks usually suggest universally applicable evaluation aspects but do not consider case-specific aspects. On the other hand, evaluation frameworks that are case specific, by eliciting user requirements, limit their output to the evaluation aspects suggested by the users in the early phases of system development. In addition, these case-specific approaches extract different sets of evaluation aspects from each case, making it challenging to collectively compare, unify, or aggregate the evaluation of a set of heterogeneous health information systems. The aim of this paper is to find a method capable of suggesting evaluation aspects for a set of one or more health information systems-whether similar or heterogeneous-by organizing, unifying, and aggregating the quality attributes extracted from those systems and from an external evaluation framework. On the basis of the available literature in semantic networks and ontologies, a method (called Unified eValuation using Ontology; UVON) was developed that can organize, unify, and aggregate the quality attributes of several health information systems into a tree-style ontology structure. The method was extended to integrate its generated ontology with the evaluation aspects suggested by model-based evaluation frameworks. An approach was developed to extract evaluation aspects from the ontology that also considers evaluation case practicalities such as the maximum number of evaluation aspects to be measured or their required degree of specificity. The method was applied and tested in Future Internet Social and Technological Alignment Research (FI-STAR), a project of 7 cloud-based eHealth applications that were developed and deployed across European Union countries. The relevance of the evaluation aspects created by the UVON method for the FI-STAR project was validated by the corresponding stakeholders of each case. These evaluation aspects were extracted from a UVON-generated ontology structure that reflects both the internally declared required quality attributes in the 7 eHealth applications of the FI-STAR project and the evaluation aspects recommended by the Model for ASsessment of Telemedicine applications (MAST) evaluation framework. The extracted evaluation aspects were used to create questionnaires (for the corresponding patients and health professionals) to evaluate each individual case and the whole of the FI-STAR project. The UVON method can provide a relevant set of evaluation aspects for a heterogeneous set of health information systems by organizing, unifying, and aggregating the quality attributes through ontological structures. Those quality attributes can be either suggested by evaluation models or elicited from the stakeholders of those systems in the form of system requirements. The method continues to be systematic, context sensitive, and relevant across a heterogeneous set of health information systems.

Field Manual of Wildlife Diseases

USGS Publications Warehouse

Franson, J. Christian; Friend, Milton; Gibbs, Samantha E.J.; Wild, Margaret A.

2015-01-01

We begin this new manual with introductory contextual and historical background about the convergence of wildlife disease with wildlife management as a wildlife conservation concern (section A, chap. 1). The remainder of the publication is focused on pragmatic information and considerations for addressing various aspects of wildlife disease. Section B focuses on concepts associated with disease surveillance and response to outbreaks, and section C deals with specific techniques for disease surveillance and investigation. Section D, “Diseases of Wild Birds,” and others that follow will address diseases of concern in various species groups. Electronic links facilitate timely access to a wide variety of supplemental information and processes relevant to content in this new version of the “Field Manual of Wildlife Diseases.”

Precision GPS ephemerides and baselines

NASA Technical Reports Server (NTRS)

1991-01-01

Based on the research, the area of precise ephemerides for GPS satellites, the following observations can be made pertaining to the status and future work needed regarding orbit accuracy. There are several aspects which need to be addressed in discussing determination of precise orbits, such as force models, kinematic models, measurement models, data reduction/estimation methods, etc. Although each one of these aspects was studied at CSR in research efforts, only points pertaining to the force modeling aspect are addressed.

Accommodating complexity and human behaviors in decision analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Backus, George A.; Siirola, John Daniel; Schoenwald, David Alan

2007-11-01

This is the final report for a LDRD effort to address human behavior in decision support systems. One sister LDRD effort reports the extension of this work to include actual human choices and additional simulation analyses. Another provides the background for this effort and the programmatic directions for future work. This specific effort considered the feasibility of five aspects of model development required for analysis viability. To avoid the use of classified information, healthcare decisions and the system embedding them became the illustrative example for assessment.

Recommendations of the VAC2VAC workshop on the design of multi-centre validation studies.

PubMed

Halder, Marlies; Depraetere, Hilde; Delannois, Frédérique; Akkermans, Arnoud; Behr-Gross, Marie-Emmanuelle; Bruysters, Martijn; Dierick, Jean-François; Jungbäck, Carmen; Kross, Imke; Metz, Bernard; Pennings, Jeroen; Rigsby, Peter; Riou, Patrice; Balks, Elisabeth; Dobly, Alexandre; Leroy, Odile; Stirling, Catrina

2018-03-01

Within the Innovative Medicines Initiative 2 (IMI 2) project VAC2VAC (Vaccine batch to vaccine batch comparison by consistency testing), a workshop has been organised to discuss ways of improving the design of multi-centre validation studies and use the data generated for product-specific validation purposes. Moreover, aspects of validation within the consistency approach context were addressed. This report summarises the discussions and outlines the conclusions and recommendations agreed on by the workshop participants. Copyright © 2018.

Conduction at the onset of chaos

NASA Astrophysics Data System (ADS)

Baldovin, Fulvio

2017-02-01

After a general discussion of the thermodynamics of conductive processes, we introduce specific observables enabling the connection of the diffusive transport properties with the microscopic dynamics. We solve the case of Brownian particles, both analytically and numerically, and address then whether aspects of the classic Onsager's picture generalize to the non-local non-reversible dynamics described by logistic map iterates. While in the chaotic case numerical evidence of a monotonic relaxation is found, at the onset of chaos complex relaxation patterns emerge.

Reentry Vehicle Flight Controls Design Guidelines: Dynamic Inversion

NASA Technical Reports Server (NTRS)

Ito, Daigoro; Georgie, Jennifer; Valasek, John; Ward, Donald T.

2002-01-01

This report addresses issues in developing a flight control design for vehicles operating across a broad flight regime and with highly nonlinear physical descriptions of motion. Specifically it addresses the need for reentry vehicles that could operate through reentry from space to controlled touchdown on Earth. The latter part of controlled descent is achieved by parachute or paraglider - or by all automatic or a human-controlled landing similar to that of the Orbiter. Since this report addresses the specific needs of human-carrying (not necessarily piloted) reentry vehicles, it deals with highly nonlinear equations of motion, and then-generated control systems must be robust across a very wide range of physics. Thus, this report deals almost exclusively with some form of dynamic inversion (DI). Two vital aspects of control theory - noninteracting control laws and the transformation of nonlinear systems into equivalent linear systems - are embodied in DI. Though there is no doubt that the mathematical tools and underlying theory are widely available, there are open issues as to the practicality of using DI as the only or primary design approach for reentry articles. This report provides a set of guidelines that can be used to determine the practical usefulness of the technique.

Molecular locks and keys: the role of small molecules in phytohormone research

PubMed Central

Fonseca, Sandra; Rosado, Abel; Vaughan-Hirsch, John; Bishopp, Anthony; Chini, Andrea

2014-01-01

Plant adaptation, growth and development rely on the integration of many environmental and endogenous signals that collectively determine the overall plant phenotypic plasticity. Plant signaling molecules, also known as phytohormones, are fundamental to this process. These molecules act at low concentrations and regulate multiple aspects of plant fitness and development via complex signaling networks. By its nature, phytohormone research lies at the interface between chemistry and biology. Classically, the scientific community has always used synthetic phytohormones and analogs to study hormone functions and responses. However, recent advances in synthetic and combinational chemistry, have allowed a new field, plant chemical biology, to emerge and this has provided a powerful tool with which to study phytohormone function. Plant chemical biology is helping to address some of the most enduring questions in phytohormone research such as: Are there still undiscovered plant hormones? How can we identify novel signaling molecules? How can plants activate specific hormone responses in a tissue-specific manner? How can we modulate hormone responses in one developmental context without inducing detrimental effects on other processes? The chemical genomics approaches rely on the identification of small molecules modulating different biological processes and have recently identified active forms of plant hormones and molecules regulating many aspects of hormone synthesis, transport and response. We envision that the field of chemical genomics will continue to provide novel molecules able to elucidate specific aspects of hormone-mediated mechanisms. In addition, compounds blocking specific responses could uncover how complex biological responses are regulated. As we gain information about such compounds we can design small alterations to the chemical structure to further alter specificity, enhance affinity or modulate the activity of these compounds. PMID:25566283

Data mining to support simulation modeling of patient flow in hospitals.

PubMed

Isken, Mark W; Rajagopalan, Balaji

2002-04-01

Spiraling health care costs in the United States are driving institutions to continually address the challenge of optimizing the use of scarce resources. One of the first steps towards optimizing resources is to utilize capacity effectively. For hospital capacity planning problems such as allocation of inpatient beds, computer simulation is often the method of choice. One of the more difficult aspects of using simulation models for such studies is the creation of a manageable set of patient types to include in the model. The objective of this paper is to demonstrate the potential of using data mining techniques, specifically clustering techniques such as K-means, to help guide the development of patient type definitions for purposes of building computer simulation or analytical models of patient flow in hospitals. Using data from a hospital in the Midwest this study brings forth several important issues that researchers need to address when applying clustering techniques in general and specifically to hospital data.

Total Pancreatectomy With Islet Autotransplantation

PubMed Central

Bellin, Melena D.; Gelrud, Andres; Arreaza-Rubin, Guillermo; Dunn, Ty B.; Humar, Abhinav; Morgan, Katherine A.; Naziruddin, Bashoo; Rastellini, Cristiana; Rickels, Michael R.; Schwarzenberg, Sarah J.; Andersen, Dana K.

2015-01-01

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases focused on research gaps and opportunities in total pancreatectomy with islet autotransplantation (TPIAT) for the management of chronic pancreatitis. The session was held on July 23, 2014 and structured into 5 sessions: (1) patient selection, indications, and timing; (2) technical aspects of TPIAT; (3) improving success of islet autotransplantation; (4) improving outcomes after total pancreatectomy; and (5) registry considerations for TPIAT. The current state of knowledge was reviewed; knowledge gaps and research needs were specifically highlighted. Common themes included the need to identify which patients best benefit from and when to intervene with TPIAT, current limitations of the surgical procedure, diabetes remission and the potential for improvement, opportunities to better address pain remission, GI complications in this population, and unique features of children with chronic pancreatitis considered for TPIAT. The need for a multicenter patient registry that specifically addresses the complexities of chronic pancreatitis and total pancreatectomy outcomes and postsurgical diabetes outcomes was repeatedly emphasized. PMID:25599324

NASA software documentation standard software engineering program

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as Standard) can be applied to the documentation of all NASA software. This Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. This basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

Low Levels of Empathic Concern Predict Utilitarian Moral Judgment

PubMed Central

Gleichgerrcht, Ezequiel; Young, Liane

2013-01-01

Is it permissible to harm one to save many? Classic moral dilemmas are often defined by the conflict between a putatively rational response to maximize aggregate welfare (i.e., the utilitarian judgment) and an emotional aversion to harm (i.e., the non-utilitarian judgment). Here, we address two questions. First, what specific aspect of emotional responding is relevant for these judgments? Second, is this aspect of emotional responding selectively reduced in utilitarians or enhanced in non-utilitarians? The results reveal a key relationship between moral judgment and empathic concern in particular (i.e., feelings of warmth and compassion in response to someone in distress). Utilitarian participants showed significantly reduced empathic concern on an independent empathy measure. These findings therefore reveal diminished empathic concern in utilitarian moral judges. PMID:23593213

Gender, aging, and the economics of "active aging": Setting a new research agenda.

PubMed

Paz, Amira; Doron, Israel; Tur-Sinai, Aviad

2018-01-01

The world is aging, and the percentages of older people are on a dramatic ascent. This dramatic demographic aging of human society is not gender neutral; it is mostly about older women. One of the key policy approaches to address the aging revolution is known as "active aging," crystalized by the WHO in 2002 by three pillars: participation, health, and security. The active aging policy has financial and economic aspects and affects both men and women. However, as argued in this article, a gender-based approach has not been adopted within the existing active aging framework. Therefore, a new gender-specific research agenda is needed, one that focuses on an interrelation between gender and different economic aspects of "active aging" from international, comparative, cultural, and longitudinal perspectives.

The Biology of Cancer Exosomes: Insights and New Perspectives.

PubMed

Ruivo, Carolina F; Adem, Bárbara; Silva, Miguel; Melo, Sónia A

2017-12-01

Exosomes are a subclass of extracellular vesicles involved in intercellular communication that are released by all cell types, including cancer cells. Cancer exosomes carry malignant information in the form of proteins, lipids, and nucleic acids that can reprogram recipient cells. Exosomes have emerged as putative biological mediators in cancer contributing to major steps of disease progression. A leading role exists for cancer exosomes in specific aspects of tumor progression: modulation of immune response, tumor microenvironment reprogramming, and metastasis. This review will address the functions attributed to cancer exosomes in these three aspects of cancer biology, highlighting recent advances and potential limitations. Finally, we explore alternative strategies to develop better models to study cancer exosomes biology. Cancer Res; 77(23); 6480-8. ©2017 AACR . ©2017 American Association for Cancer Research.

Privacy and data security in E-health: requirements from the user's perspective.

PubMed

Wilkowska, Wiktoria; Ziefle, Martina

2012-09-01

In this study two currently relevant aspects of using medical assistive technologies were addressed-security and privacy. In a two-step empirical approach that used focus groups (n = 19) and a survey (n = 104), users' requirements for the use of medical technologies were collected and evaluated. Specifically, we focused on the perceived importance of data security and privacy issues. Outcomes showed that both security and privacy aspects play an important role in the successful adoption of medical assistive technologies in the home environment. In particular, analysis of data with respect to gender, health-status and age (young, middle-aged and old users) revealed that females and healthy adults require, and insist on, the highest security and privacy standards compared with males and the ailing elderly.

Low levels of empathic concern predict utilitarian moral judgment.

PubMed

Gleichgerrcht, Ezequiel; Young, Liane

2013-01-01

Is it permissible to harm one to save many? Classic moral dilemmas are often defined by the conflict between a putatively rational response to maximize aggregate welfare (i.e., the utilitarian judgment) and an emotional aversion to harm (i.e., the non-utilitarian judgment). Here, we address two questions. First, what specific aspect of emotional responding is relevant for these judgments? Second, is this aspect of emotional responding selectively reduced in utilitarians or enhanced in non-utilitarians? The results reveal a key relationship between moral judgment and empathic concern in particular (i.e., feelings of warmth and compassion in response to someone in distress). Utilitarian participants showed significantly reduced empathic concern on an independent empathy measure. These findings therefore reveal diminished empathic concern in utilitarian moral judges.

Resting respiratory sinus arrhythmia is associated with tonic positive emotionality.

PubMed

Oveis, Christopher; Cohen, Adam B; Gruber, June; Shiota, Michelle N; Haidt, Jonathan; Keltner, Dacher

2009-04-01

Resting respiratory sinus arrhythmia (RSAREST) indexes important aspects of individual differences in emotionality. In the present investigation, the authors address whether RSAREST is associated with tonic positive or negative emotionality, and whether RSAREST relates to phasic emotional responding to discrete positive emotion-eliciting stimuli. Across an 8-month, multiassessment study of first-year university students (n = 80), individual differences in RSAREST were associated with positive but not negative tonic emotionality, assessed at the level of personality traits, long-term moods, the disposition toward optimism, and baseline reports of current emotional states. RSAREST was not related to increased positive emotion, or stimulus-specific emotion, in response to compassion-, awe-, or pride-inducing stimuli. These findings suggest that resting RSA indexes aspects of a person's tonic positive emotionality. (c) 2009 APA, all rights reserved.

A Conceptual Model for Developing Mindsets for Strategic Insight under Conditions of Complexity and High Uncertainty

ERIC Educational Resources Information Center

Yorks, Lyle; Nicolaides, Aliki

2012-01-01

This article addresses an important, yet often underattended to, aspect of the strategy development process: fostering the use of strategic learning practices in the simultaneous practice of developing strategy and cultivating strategic mindset awareness. The need for addressing this aspect of the strategy development process is increasingly…

Avoid, Control, Succumb, or Balance: Engineering Students' Approaches to a Wicked Sustainability Problem

NASA Astrophysics Data System (ADS)

Lönngren, Johanna; Ingerman, Åke; Svanström, Magdalena

2017-08-01

Wicked sustainability problems (WSPs) are an important and particularly challenging type of problem. Science and engineering education can play an important role in preparing students to deal with such problems, but current educational practice may not adequately prepare students to do so. We address this gap by providing insights related to students' abilities to address WSPs. Specifically, we aim to (I) describe key constituents of engineering students' approaches to a WSP, (II) evaluate these approaches in relation to the normative context of education for sustainable development (ESD), and (III) identify relevant aspects of learning related to WSPs. Aim I is addressed through a phenomenographic study, while aims II and III are addressed by relating the results to research literature about human problem solving, sustainable development, and ESD. We describe four qualitatively different ways of approaching a specific WSP, as the outcome of the phenomenographic study: A. Simplify and avoid, B. Divide and control, C. Isolate and succumb, and D. Integrate and balance. We identify approach D as the most appropriate approach in the context of ESD, while A and C are not. On this basis, we identify three learning objectives related to students' abilities to address WSPs: learn to use a fully integrative approach, distinguish WSPs from tame and well-structured problems, and understand and consider the normative context of SD. Finally, we provide recommendations for how these learning objectives can be used to guide the design of science and engineering educational activities.

Method for the evaluation 3D noncontact inspection systems

NASA Astrophysics Data System (ADS)

Harding, Kevin

2011-08-01

Three dimensional, optical measurement systems are becoming more widely used in applications ranging from aerospace to automotive. These systems offer the potential for high speed, good accuracy, and more complete information than older contact based technology. However, the primary standards employed by many to evaluate these systems were specifically designed around touch probe based coordinate measurement machines (CMMs). These standards were designed to work with the limitations of touch probes, and in many cases cannot measure the types of features and errors associated with non-contact systems. This paper will discuss the deficiencies of employing contact based characterization tests to non-contact systems, and suggest a new set of tests specifically to cover the many aspects pertinent to non-contact, optical 3D measurement systems. Some of the performance aspects addressed in this characterization method include: sensitivity to surface reflectivity and roughness, the effect of angle of incidence of measurements, means to characterize volumetric variations that may fit complex functions, and considerations of both spatial and depth resolutions. Specific application areas will be discussed as well as the use of artifacts to provide practical functional data that can predict system performance on real world parts.

["...such refuges are the collections and museums, which represent the current aspects of science, and prepare for its future". Social aspects of anatomy and the collections of the Vienna medical faculty, 1790 - 1840].

PubMed

Oppenauer, Markus

2014-01-01

This paper arises out of my research which I have been conducting in the context of my dissertation project. It explores the relationship between teaching, research and collecting practices in Viennese anatomy during the late eighteenth and early nineteenth century. In a time in which Viennese medicine tried to reinvent itself through both the creation of a new curriculum and several other institutional measures the practice of establishing comparative and human anatomical collections can be seen as a strategic key field of action. By concentrating on scientific journals, popular texts, catalogues, correspondences and specimens this paper aims at revealing specific social systems which must be understood as parts of the 'social history' of Viennese anatomy. By looking closely at these social aspects of anatomical teaching and research, this work tries to contribute to recent discussions addressed by historians of science and medicine.

Governance, agricultural intensification, and land sparing in tropical South America.

PubMed

Ceddia, Michele Graziano; Bardsley, Nicholas Oliver; Gomez-y-Paloma, Sergio; Sedlacek, Sabine

2014-05-20

In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South American countries and quantify the effects of major determinants of agricultural land expansion, including various dimensions of governance, over the period 1970-2006. The results indicate that the effect of agricultural intensification on agricultural expansion is conditional on the quality and type of governance. When considering conventional aspects of governance, agricultural intensification leads to an expansion of agricultural area when governance scores are high. When looking specifically at environmental aspects of governance, intensification leads to a spatial contraction of agriculture when governance scores are high, signaling a sustainable intensification process.

Governance, agricultural intensification, and land sparing in tropical South America

PubMed Central

Ceddia, Michele Graziano; Bardsley, Nicholas Oliver; Gomez-y-Paloma, Sergio; Sedlacek, Sabine

2014-01-01

In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South American countries and quantify the effects of major determinants of agricultural land expansion, including various dimensions of governance, over the period 1970–2006. The results indicate that the effect of agricultural intensification on agricultural expansion is conditional on the quality and type of governance. When considering conventional aspects of governance, agricultural intensification leads to an expansion of agricultural area when governance scores are high. When looking specifically at environmental aspects of governance, intensification leads to a spatial contraction of agriculture when governance scores are high, signaling a sustainable intensification process. PMID:24799696

Security and privacy in molecular communication and networking: opportunities and challenges.

PubMed

Loscrí, Valeria; Marchal, César; Mitton, Nathalie; Fortino, Giancarlo; Vasilakos, Athanasios V

2014-09-01

Molecular Communication (MC) is an emerging and promising communication paradigm for several multi-disciplinary domains like bio-medical, industry and military. Differently to the traditional communication paradigm, the information is encoded on the molecules, that are then used as carriers of information. Novel approaches related to this new communication paradigm have been proposed, mainly focusing on architectural aspects and categorization of potential applications. So far, security and privacy aspects related to the molecular communication systems have not been investigated at all and represent an open question that need to be addressed. The main motivation of this paper lies on providing some first insights about security and privacy aspects of MC systems, by highlighting the open issues and challenges and above all by outlining some specific directions of potential solutions. Existing cryptographic methods and security approaches are not suitable for MC systems since do not consider the pecific issues and challenges, that need ad-hoc solutions. We will discuss directions in terms of potential solutions by trying to highlight the main advantages and potential drawbacks for each direction considered. We will try to answer to the main questions: 1) why this solution can be exploited in the MC field to safeguard the system and its reliability? 2) which are the main issues related to the specific approach?

Robotic Reconnaissance Missions to Small Bodies and Their Potential Contributions to Human Exploration

NASA Technical Reports Server (NTRS)

Abell, P. A.; Rivkin, A. S.

2015-01-01

Introduction: Robotic reconnaissance missions to small bodies will directly address aspects of NASA's Asteroid Initiative and will contribute to future human exploration. The NASA Asteroid Initiative is comprised of two major components: the Grand Challenge and the Asteroid Mission. The first component, the Grand Challenge, focuses on protecting Earth's population from asteroid impacts by detecting potentially hazardous objects with enough warning time to either prevent them from impacting the planet, or to implement civil defense procedures. The Asteroid Mission involves sending astronauts to study and sample a near- Earth asteroid (NEA) prior to conducting exploration missions of the Martian system, which includes Phobos and Deimos. The science and technical data obtained from robotic precursor missions that investigate the surface and interior physical characteristics of an object will help identify the pertinent physical properties that will maximize operational efficiency and reduce mission risk for both robotic assets and crew operating in close proximity to, or at the surface of, a small body. These data will help fill crucial strategic knowledge gaps (SKGs) concerning asteroid physical characteristics that are relevant for human exploration considerations at similar small body destinations. Small Body Strategic Knowledge Gaps: For the past several years NASA has been interested in identifying the key SKGs related to future human destinations. These SKGs highlight the various unknowns and/or data gaps of targets that the science and engineering communities would like to have filled in prior to committing crews to explore the Solar System. An action team from the Small Bodies Assessment Group (SBAG) was formed specifically to identify the small body SKGs under the direction of the Human Exploration and Operations Missions Directorate (HEOMD), given NASA's recent interest in NEAs and the Martian moons as potential human destinations [1]. The action team organized the SKGs into four broad themes: 1) Identify human mission targets; 2) Understand how to work on and interact with the small body surface; 3) Understand the small body environment and its potential risk/benefit to crew, systems, and operational assets; and 4) Understand the small body resource potential. Each of these themes were then further subdivided into categories to address specific SKG issues. Robotic Precursor Contributions to SKGs: Robotic reconnaissance missions should be able to address specific aspects related to SKG themes 1 through 4. Theme 1 deals with the identification of human mission targets within the NEA population. The current guideline indicates that human missions to fastspinning, tumbling, or binary asteroids may be too risky to conduct successfully from an operational perspective. However, no spacecraft mission has been to any of these types of NEAs before. Theme 2 addresses the concerns about interacting on the small body surface under microgravity conditions, and how the surface and/or sub-surface properties affect or restrict the interaction for human exploration. The combination of remote sensing instruments and in situ payloads will provide good insight into the asteroid's surface and subsurface properties. SKG theme 3 deals with the environment in and around the small body that may present a nuisance or hazard to any assets operating in close proximity. Impact and surface experiments will help address issues related to particle size, particle longevity, internal structure, and the near-surface mechanical stability of the asteroid. Understanding or constraining these physical characteristics are important for mission planning. Theme 4 addresses the resource potential of the small body. This is a particularly important aspect of human exploration since the identification and utilization of resources is a key aspect for deep space mission architectures to the Martian system (i.e., Phobos and Deimos). Conclusions: Robotic reconnaissance of small bodies can provide a wealth of information relevant to the science and planetary defense of NEAs. However, such missions to investigate NEAs can also provide key insights into small body strategic knowledge gaps and contribute to the overall success for human exploration missions to asteroids.

Addressing Weight Loss Recidivism: A Clinical Focus on Metabolic Rate and the Psychological Aspects of Obesity

PubMed Central

Grattan, Bruce J.; Connolly-Schoonen, Josephine

2012-01-01

Obesity in the United States has reached epidemic proportions and has become an unprecedented public health burden. This paper returns to the evidence for metabolic rate set points and emphasizes the clinical importance of addressing changes in metabolic rate throughout the weight loss process. In addition to the importance of clinically attending to the modulation of metabolic rate, the psychological aspects of obesity are addressed as part of the need to holistically treat obesity. PMID:24527265

Earthquake ground motion: Chapter 3

USGS Publications Warehouse

Luco, Nicolas; Kircher, Charles A.; Crouse, C. B.; Charney, Finley; Haselton, Curt B.; Baker, Jack W.; Zimmerman, Reid; Hooper, John D.; McVitty, William; Taylor, Andy

2016-01-01

Most of the effort in seismic design of buildings and other structures is focused on structural design. This chapter addresses another key aspect of the design process—characterization of earthquake ground motion into parameters for use in design. Section 3.1 describes the basis of the earthquake ground motion maps in the Provisions and in ASCE 7 (the Standard). Section 3.2 has examples for the determination of ground motion parameters and spectra for use in design. Section 3.3 describes site-specific ground motion requirements and provides example site-specific design and MCER response spectra and example values of site-specific ground motion parameters. Section 3.4 discusses and provides an example for the selection and scaling of ground motion records for use in various types of response history analysis permitted in the Standard.

Exploiting microRNA Specificity and Selectivity: Paving a Sustainable Path Towards Precision Medicine.

PubMed

Santulli, Gaetano

2015-01-01

In his State of the Union address before both chambers of the US Congress, President Barack Obama called for increased investment in US infrastructure and research and announced the launch of a new Precision Medicine Initiative, aiming to accelerate biomedical discovery. Due to their well-established selectivity and specificity, microRNAs can represent a useful tool, both in diagnosis and therapy, in forging the path towards the achievement of precision medicine. This introductory chapter represents a guide for the Reader in examining the functional roles of microRNAs in the most diverse aspects of clinical practice, which will be explored in this third volume of the microRNA trilogy.

Exploiting microRNA Specificity and Selectivity: Paving a Sustainable Path Towards Precision Medicine

PubMed Central

2016-01-01

In his State of the Union address before both chambers of the US Congress, President Barack Obama called for increased investment in US infrastructure and research and announced the launch of a new Precision Medicine Initiative, aiming to accelerate biomedical discovery. Due to their well-established selectivity and specificity, microRNAs can represent a useful tool, both in diagnosis and therapy, in forging the path towards the achievement of precision medicine. This introductory chapter represents a guide for the Reader in examining the functional roles of microRNAs in the most diverse aspects of clinical practice, which will be explored in this third volume of the microRNA trilogy. PMID:26663175

Science Objectives and Design of the European Seas Observatory NETwork (ESONET)

NASA Astrophysics Data System (ADS)

Ruhl, H.; Géli, L.; Karstensen, J.; Colaço, A.; Lampitt, R.; Greinert, J.; Phannkuche, O.; Auffret, Y.

2009-04-01

The needs for a network of ocean observing systems cross many applied and research areas of earth and marine science. Many of the science areas that can be examined using such systems have direct impacts on societal health and well being and our understanding of ocean function in a shifting climate. The European Seas Observatory NETwork (ESONET) Network of Excellence has been evaluating ocean observatory design requirements, data management needs, standardization and interoperability concerns, social implications, outreach and education, as well as financial and legal aspects of developing such a system. ESONET has great potential to address a growing set of Earth science questions that require a broad and integrated network of ocean and seafloor observations. ESONET activities are also importantly integrating researchers in the European Community, as well as internationally. There is now wide recognition that research addressing science questions of international priority, such as understanding the potential impacts of climate change or geohazards like earthquakes and tsunamis should be conducted in a framework that can address questions across adequate temporal and spatial scales. We will present the relevant science priorities in the four interconnected fields of geoscience, physical oceanography, biogeochemistry, and marine ecology, and some of the practical ways in which these questions can be addressed using ESONET. Several key questions persist that will require comprehensive interdisciplinary approaches including: How can monitoring of factors such as seismic activity, fluid pore chemistry and pressure, improve seismic, slope failure, and tsunami warning? To what extent do seabed processes influence ocean physics, biogeochemistry, and marine ecosystems? How are physical and biogeochemical processes that occur at differing scales related? What aspects of physical oceanography and biogeochemical cycling will be most sensitive to climate change? What will the important feedbacks of potential ecological change be on biogeochemical cycles? What are the factors that control the distribution and abundance of marine life and what will the influence of anthropogenic change be? We will outline a set of science objectives and observation parameters to be collected at all ESONET sites, as well as a set of rather specific objectives and thus parameters that might only be measured at some sites. We will also present the preliminary module specifications now being considered by ESONET. In a practical sense the observatory design has been divided into those that will be included in a so called ‘generic' module and those that will be part of science-specific modules. Outlining preliminary module specifications is required to move forward with studies of observatory design and operation. These specifications are importantly provisional and can be updated as science needs and feasibility change. A functional cleavage not only comes between aspects that are considered generic or specific, but also the settings in which those systems will be used. For example, some modules will be on the seabed and some will be moored in the water column. In order to address many of the questions posed above ESONET users will require other supporting data from other programs from local to international levels. Examples of these other data sources include satellite oceanographic data, climatic data, air-sea interface data, and the known distribution and abundances of marine fauna. Thus the connection of ESONET to other programs is integral to its success. The development of ESONET provides a substantial opportunity for ocean science to evolve in Europe. Furthermore, ESONET and several other developing ocean observatory programs are integrating into larger science frameworks including the Global Earth Observation System of Systems (GEOSS) and Global Monitoring of Environment and Security (GMES) programs. It is only in a greater integrated framework that the full potential of the component systems will be realized.

Tailoring Software Inspections for Aspect-Oriented Programming

ERIC Educational Resources Information Center

Watkins, Charlette Ward

2009-01-01

Aspect-Oriented Software Development (AOSD) is a new approach that addresses limitations inherent in conventional programming, especially the principle of separation of concerns by emphasizing the encapsulation and modularization of crosscutting concerns through a new abstraction, the "aspect." Aspect-oriented programming is an emerging AOSD…

Complex Genetics of Behavior: BXDs in the Automated Home-Cage.

PubMed

Loos, Maarten; Verhage, Matthijs; Spijker, Sabine; Smit, August B

2017-01-01

This chapter describes a use case for the genetic dissection and automated analysis of complex behavioral traits using the genetically diverse panel of BXD mouse recombinant inbred strains. Strains of the BXD resource differ widely in terms of gene and protein expression in the brain, as well as in their behavioral repertoire. A large mouse resource opens the possibility for gene finding studies underlying distinct behavioral phenotypes, however, such a resource poses a challenge in behavioral phenotyping. To address the specifics of large-scale screening we describe how to investigate: (1) how to assess mouse behavior systematically in addressing a large genetic cohort, (2) how to dissect automation-derived longitudinal mouse behavior into quantitative parameters, and (3) how to map these quantitative traits to the genome, deriving loci underlying aspects of behavior.

Modeling Submarine Lava Flow with ASPECT

NASA Astrophysics Data System (ADS)

Storvick, E. R.; Lu, H.; Choi, E.

2017-12-01

Submarine lava flow is not easily observed and experimented on due to limited accessibility and challenges posed by the fast solidification of lava and the associated drastic changes in rheology. However, recent advances in numerical modeling techniques might address some of these challenges and provide unprecedented insight into the mechanics of submarine lava flow and conditions determining its wide-ranging morphologies. In this study, we explore the applicability ASPECT, Advanced Solver for Problems in Earth's ConvecTion, to submarine lava flow. ASPECT is a parallel finite element code that solves problems of thermal convection in the Earth's mantle. We will assess ASPECT's capability to model submarine lava flow by observing models of lava flow morphology simulated with GALE, a long-term tectonics finite element analysis code, with models created using comparable settings and parameters in ASPECT. From these observations we will contrast the differing models in order to identify the benefits of each code. While doing so, we anticipate we will learn about the conditions required for end-members of lava flow morphology, for example, pillows and sheet flows. With ASPECT specifically we focus on 1) whether the lava rheology can be implemented; 2) how effective the AMR is in resolving morphologies of the solidified crust; 3) whether and under what conditions the end-members of the lava flow morphologies, pillows and sheets, can be reproduced.

A Review of Agents for Palliative Sedation/Continuous Deep Sedation: Pharmacology and Practical Applications.

PubMed

Bodnar, John

2017-03-01

Continuous deep sedation at the end of life is a specific form of palliative sedation requiring a care plan that essentially places and maintains the patient in an unresponsive state because their symptoms are refractory to any other interventions. Because this application is uncommon, many providers may lack practical experience in this specialized area and resources they can access are outdated, nonspecific, and/or not comprehensive. The purpose of this review is to provide an evidence- and experience-based reference that specifically addresses those medications and regimens and their practical applications for this very narrow, but vital, aspect of hospice care. Patient goals in a hospital and hospice environments are different, so the manner in which widely used sedatives are dosed and applied can differ greatly as well. Parameters applied in end-of-life care that are based on experience and a thorough understanding of the pharmacology of those medications will differ from those applied in an intensive care unit or other medical environments. By recognizing these different goals and applying well-founded regimens geared specifically for end-of-life sedation, we can address our patients' symptoms in a more timely and efficacious manner.

Xenotransplantation-theological-ethical considerations in an interdisciplinary symposium.

PubMed

Sautermeister, Jochen; Mathieu, Richard; Bogner, Veronika

2015-01-01

Unlike allotransplantation, reflections on xenotransplantation are infrequent in theological literature. However, xenotransplantation poses questions specifically concerning ethical and theological aspects that are imperative to address, such as personal identity between the poles of body, soul, and mind, the relationship between humans and animals, as well as challenges regarding specific issues of medical and social ethics. This study summarizes the lectures of the symposium on "Xenotransplantation-a challenge to theological ethics," which took place in Munich from September 30 until October 2, 2013, and analyses the implications of xenotransplantation from the perspectives of Christian theological ethics, biblical theology, and systematic theology. Furthermore, the issue of xenotransplantation is addressed from the perspectives of Judaism and Islam. Beyond these theological deliberations, the metaphorical and religious meaning of the human heart, which may have an impact on the societal acceptability of xenotransplantation, as well as the Christian notion of compassion regarding animals, is analyzed from the perspective of historical sciences. According to the perspectives of Christianity, Judaism, and Islam, there are no specifically religious fundamental and generally binding reasons to prohibit xenotransplantation as a means of treating grave and life-threatening organ insufficiencies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Optimizing spatial and temporal treatments to maintain effective fire and non-fire fuels treatments at landscape scales

Treesearch

J. Greg Jones; Woodam Chung; Carl Seielstad; Janet Sullivan; Kurt Krueger

2010-01-01

There is a recognized need to apply and maintain fuel treatments to reduce catastrophic wildland fires. A number of models and decision support systems have been developed for addressing different aspects of fuel treatments while considering other important resource management issues and constraints. Although these models address diverse aspects of the fuel treatment-...

A Multiple Case Study of Mental Health Interventions in Middle Income Countries: Considering the Science of Delivery.

PubMed

Kidd, Sean A; Madan, Athena; Rallabandi, Susmitha; Cole, Donald C; Muskat, Elisha; Raja, Shoba; Wiljer, David; Aylward, David; McKenzie, Kwame

2016-01-01

In the debate in global mental health about the most effective models for developing and scaling interventions, there have been calls for the development of a more robust literature regarding the "non-specific", science of delivery aspects of interventions that are locally, contextually, and culturally relevant. This study describes a rigorous, exploratory, qualitative examination of the key, non-specific intervention strategies of a diverse group of five internationally-recognized organizations addressing mental illness in middle income countries (MICs). A triangulated approach to inquiry was used with semi-structured interviews conducted with service recipients, service providers and leaders, and key community partners (N = 159). The interview focus was upon processes of implementation and operation. A grounded theory-informed analysis revealed cross cutting themes of: a holistic conceptualization of mental health problems, an intensive application of principles of leverage and creating the social, cultural, and policy "space" within which interventions could be applied and resourced. These findings aligned with key aspects of systems dynamic theory suggesting that it might be a helpful framework in future studies of mental health service implementation in MICs.

'You are inferior!' Revisiting the expressivist argument.

PubMed

Hofmann, Bjørn

2017-09-01

According to the expressivist argument the choice to use biotechnologies to prevent the birth of individuals with specific disabilities is an expression of disvalue for existing people with this disability. The argument has stirred a lively debate and has recently received renewed attention. This article starts with presenting the expressivist argument and its core elements. It then goes on to present and examine the counter-arguments before it addresses some aspects that have gained surprisingly little attention. The analysis demonstrates that the expressivist argument has a wide range of underpinnings and that counter-arguments tend to focus on only a few of these. It also reveals an important aspect that appears to have been ignored, i.e., that people do not select foetuses based on chromosomes or other biological traits, but based on characteristics of living persons with specific disabilities. This makes it more difficult to undermine the claim that negative selection of foetuses expresses a disvaluing of persons with such disabilities. It leaves the expressivist argument with a strong bite still. © 2017 John Wiley & Sons Ltd.

Method and apparatus for monitoring plasma processing operations

DOEpatents

Smith, Jr., Michael Lane; Stevenson, Joel O'Don; Ward, Pamela Peardon Denise

2001-01-01

The invention generally relates to various aspects of a plasma process, and more specifically the monitoring of such plasma processes. One aspect relates in at least some manner to calibrating or initializing a plasma monitoring assembly. This type of calibration may be used to address wavelength shifts, intensity shifts, or both associated with optical emissions data obtained on a plasma process. A calibration light may be directed at a window through which optical emissions data is being obtained to determine the effect, if any, that the inner surface of the window is having on the optical emissions data being obtained therethrough, the operation of the optical emissions data gathering device, or both. Another aspect relates in at least some manner to various types of evaluations which may be undertaken of a plasma process which was run, and more typically one which is currently being run, within the processing chamber. Plasma health evaluations and process identification through optical emissions analysis are included in this aspect. Yet another aspect associated with the present invention relates in at least some manner to the endpoint of a plasma process (e.g., plasma recipe, plasma clean, conditioning wafer operation) or discrete/discernible portion thereof (e.g., a plasma step of a multiple step plasma recipe). A final aspect associated with the present invention relates to how one or more of the above-noted aspects may be implemented into a semiconductor fabrication facility, such as the distribution of wafers to a wafer production system.

Method and apparatus for monitoring plasma processing operations

DOEpatents

Smith, Jr., Michael Lane; Stevenson, Joel O'Don; Ward, Pamela Peardon Denise

2001-01-01

The invention generally relates to various aspects of a plasma process, and more specifically the monitoring of such plasma processes. One aspect relates in at least some manner to calibrating or initializing a plasma monitoring assembly. This type of calibration may be used to address wavelength shifts, intensity shifts, or both associated with optical emissions data obtained on a plasma process. A calibration light may be directed at a window through which optical emissions data is being obtained to determine the effect, if any, that the inner surface of the window is having on the optical emissions data being obtained therethrough, the operation of the optical emissions data gathering device, or both. Another aspect relates in at least some manner to various types of evaluations which may be undertaken of a plasma process which was run, and more typically one which is currently being run, within the processing chamber. Plasma health evaluations and process identification through optical emissions analysis are included in this aspect. Yet another aspect associated with the present invention relates in at least some manner to the endpoint of a plasma process (e.g., plasma recipe, plasma clean, conditioning wafer operation) or discrete/discemible portion thereof (e.g., a plasma step of a multiple step plasma recipe). A final aspect associated with the present invention relates to how one or more of the above-noted aspects may be implemented into a semiconductor fabrication facility, such as the distribution of wafers to a wafer production system.

Method and apparatus for monitoring plasma processing operations

DOEpatents

Smith, Jr., Michael Lane; Stevenson, Joel O'Don; Ward, Pamela Peardon Denise

2000-01-01

The invention generally relates to various aspects of a plasma process, and more specifically the monitoring of such plasma processes. One aspect relates in at least some manner to calibrating or initializing a plasma monitoring assembly. This type of calibration may be used to address wavelength shifts, intensity shifts, or both associated with optical emissions data obtained on a plasma process. A calibration light may be directed at a window through which optical emissions data is being obtained to determine the effect, if any, that the inner surface of the window is having on the optical emissions data being obtained therethrough, the operation of the optical emissions data gathering device, or both. Another aspect relates in at least some manner to various types of evaluations which may be undertaken of a plasma process which was run, and more typically one which is currently being run, within the processing chamber. Plasma health evaluations and process identification through optical emissions analysis are included in this aspect. Yet another aspect associated with the present invention relates in at least some manner to the endpoint of a plasma process (e.g., plasma recipe, plasma clean, conditioning wafer operation) or discrete/discernible portion thereof (e.g., a plasma step of a multiple step plasma recipe). A final aspect associated with the present invention relates to how one or more of the above-noted aspects may be implemented into a semiconductor fabrication facility, such as the distribution of wafers to a wafer production system.

Method and apparatus for monitoring plasma processing operations

DOEpatents

Smith, Jr., Michael Lane; Stevenson, Joel O'Don; Ward, Pamela Peardon Denise

2002-07-16

The invention generally relates to various aspects of a plasma process, and more specifically the monitoring of such plasma processes. One aspect relates in at least some manner to calibrating or initializing a plasma monitoring assembly. This type of calibration may be used to address wavelength shifts, intensity shifts, or both associated with optical emissions data obtained on a plasma process. A calibration light may be directed at a window through which optical emissions data is being obtained to determine the effect, if any, that the inner surface of the window is having on the optical emissions data being obtained therethrough, the operation of the optical emissions data gathering device, or both. Another aspect relates in at least some manner to various types of evaluations which may be undertaken of a plasma process which was run, and more typically one which is currently being run, within the processing chamber. Plasma health evaluations and process identification through optical emissions analysis are included in this aspect. Yet another aspect associated with the present invention relates in at least some manner to the endpoint of a plasma process (e.g., plasma recipe, plasma clean, conditioning wafer operation) or discrete/discernible portion thereof (e.g., a plasma step of a multiple step plasma recipe). A final aspect associated with the present invention relates to how one or more of the above-noted aspects may be implemented into a semiconductor fabrication facility, such as the distribution of wafers to a wafer production system.

Infectious disease-related laws: prevention and control measures.

PubMed

Park, Mijeong

2017-01-01

This study examines recently revised Korean government legislation addressing global infectious disease control for public health emergency situations, with the aim of proposing more rational, effective and realistic interpretations and applications for improvement of law. The Korea reported its first laboratory-confirmed case of Middle East Respiratory Syndrome (MERS) coronavirus on May 20, 2015. Since the first indexed case, Korean public health authorities enforced many public health measures that were not authorized in the law; the scope of the current law was too limited to cover MERS. Korea has three levels of government: the central government, special self-governing provinces, and si/gun/gu. Unfortunately, the Infectious Disease Control and Prevention Act does not designate the specific roles of each level of government, and does not state how these governmental branches should be vertically integrated in a state of emergency. When thinking about these policy questions, we should be especially concerned about introducing a new act that deals with all matters relevant to emerging infectious diseases. The aim would be to develop a structure that specifies the roles of each level of government, and facilitates the close collaboration among them, then enacting this in law for the prevention and response of infectious disease. To address this problem, after analyzing the national healthcare infrastructure along with the characteristics of emerging infectious diseases, we propose the revision of the relevant law(s) in terms of governance aspects, emergency medical countermeasure aspects, and the human rights aspect.

Infectious disease-related laws: prevention and control measures

PubMed Central

2017-01-01

OBJECTIVES This study examines recently revised Korean government legislation addressing global infectious disease control for public health emergency situations, with the aim of proposing more rational, effective and realistic interpretations and applications for improvement of law. METHODS The Korea reported its first laboratory-confirmed case of Middle East Respiratory Syndrome (MERS) coronavirus on May 20, 2015. Since the first indexed case, Korean public health authorities enforced many public health measures that were not authorized in the law; the scope of the current law was too limited to cover MERS. Korea has three levels of government: the central government, special self-governing provinces, and si/gun/gu. Unfortunately, the Infectious Disease Control and Prevention Act does not designate the specific roles of each level of government, and does not state how these governmental branches should be vertically integrated in a state of emergency. RESULTS When thinking about these policy questions, we should be especially concerned about introducing a new act that deals with all matters relevant to emerging infectious diseases. The aim would be to develop a structure that specifies the roles of each level of government, and facilitates the close collaboration among them, then enacting this in law for the prevention and response of infectious disease. CONCLUSIONS To address this problem, after analyzing the national healthcare infrastructure along with the characteristics of emerging infectious diseases, we propose the revision of the relevant law(s) in terms of governance aspects, emergency medical countermeasure aspects, and the human rights aspect. PMID:28774161

Charles Darwin and Evolution: Illustrating Human Aspects of Science

NASA Astrophysics Data System (ADS)

Kampourakis, Kostas; McComas, William F.

2010-06-01

Recently, the nature of science (NOS) has become recognized as an important element within the K-12 science curriculum. Despite differences in the ultimate lists of recommended aspects, a consensus is emerging on what specific NOS elements should be the focus of science instruction and inform textbook writers and curriculum developers. In this article, we suggest a contextualized, explicit approach addressing one core NOS aspect: the human aspects of science that include the domains of creativity, social influences and subjectivity. To illustrate these ideas, we have focused on Charles Darwin, a scientist whose life, work and thought processes were particularly well recorded at the time and analyzed by scholars in the succeeding years. Historical facts are discussed and linked to core NOS ideas. Creativity is illustrated through the analogies between the struggle for existence in human societies and in nature, between artificial and natural selection, and between the division of labor in human societies and in nature. Social influences are represented by Darwin’s aversion of criticism of various kinds and by his response to the methodological requirements of the science of that time. Finally, subjectivity is discussed through Darwin’s development of a unique but incorrect source for the origin of variations within species.

SoftLab: A Soft-Computing Software for Experimental Research with Commercialization Aspects

NASA Technical Reports Server (NTRS)

Akbarzadeh-T, M.-R.; Shaikh, T. S.; Ren, J.; Hubbell, Rob; Kumbla, K. K.; Jamshidi, M

1998-01-01

SoftLab is a software environment for research and development in intelligent modeling/control using soft-computing paradigms such as fuzzy logic, neural networks, genetic algorithms, and genetic programs. SoftLab addresses the inadequacies of the existing soft-computing software by supporting comprehensive multidisciplinary functionalities from management tools to engineering systems. Furthermore, the built-in features help the user process/analyze information more efficiently by a friendly yet powerful interface, and will allow the user to specify user-specific processing modules, hence adding to the standard configuration of the software environment.

Nurse Leadership and Informatics Competencies: Shaping Transformation of Professional Practice.

PubMed

Kennedy, Margaret Ann; Moen, Anne

2017-01-01

Nurse leaders must demonstrate capacities and develop specific informatics competencies in order to provide meaningful leadership and support ongoing transformation of the healthcare system. Concurrently, staff informatics competencies must be planned and fostered to support critical principles of transformation and patient safety in practice, advance evidence-informed practice, and enable nursing to flourish in complex digital environments across the healthcare continuum. In addition to nurse leader competencies, two key aspects of leadership and informatics competencies will be addressed in this chapter - namely, the transformation of health care and preparation of the nursing workforce.

Technology update: Tethered aerostat structural design and material developments

NASA Technical Reports Server (NTRS)

Witherow, R. G.

1975-01-01

Requirements exist for an extremely stable, high performance, all-weather tethered aerostat system. This requirement has been satisfied by a 250,000 cubic foot captive buoyant vehicle as demonstrated by over a year of successful field operations. This achievement required significant advancements in several technology areas including composite materials design, aerostatics and aerodynamics, structural design, electro-mechanical design, vehicle fabrication and mooring operations. This paper specifically addresses the materials and structural design aspects of pressurized buoyant vehicles as related to the general class of Lighter Than Air vehicles.

Information Technology on Screen: New Approaches in Viewdata, Teletext and Cable. Proceedings of the Joint One Day Seminar held by Aslib/Institute of Information Scientists/Library Association at the Polytechnic of the South Bank (November 8, 1982). LA Conference Proceedings Series in Library Automation: 2.

ERIC Educational Resources Information Center

Library Association, London (England).

The most important developments now taking place or being planned are emphasized in this collection of eight papers on the emerging aspects of information technology. In addition to an introduction by Ric Foot and a keynote address by John Butcher, the specific papers are as follows: (1) "Telesoftware as Part of the Knowledge Network,"…

Species-specific photorespiratory rate, drought tolerance and isoprene emission rate in plants.

PubMed

Dani, K G Srikanta; Jamie, Ian M; Prentice, I Colin; Atwell, Brian J

2015-01-01

The effect of drought on plant isoprene emission varies tremendously across species and environments. It was recently shown that an increased ratio of photosynthetic electron transport rate (ETR) to net carbon assimilation rate (NAR) consistently supported increased emission under drought. In this commentary, we highlight some of the physiological aspects of drought tolerance that are central to the observed variability. We briefly discuss some of the issues that must be addressed in order to refine our understanding of plant isoprene emission response to drought and increasing global temperature.

Mixture-Tuned, Clutter Matched Filter for Remote Detection of Subpixel Spectral Signals

NASA Technical Reports Server (NTRS)

Thompson, David R.; Mandrake, Lukas; Green, Robert O.

2013-01-01

Mapping localized spectral features in large images demands sensitive and robust detection algorithms. Two aspects of large images that can harm matched-filter detection performance are addressed simultaneously. First, multimodal backgrounds may thwart the typical Gaussian model. Second, outlier features can trigger false detections from large projections onto the target vector. Two state-of-the-art approaches are combined that independently address outlier false positives and multimodal backgrounds. The background clustering models multimodal backgrounds, and the mixture tuned matched filter (MT-MF) addresses outliers. Combining the two methods captures significant additional performance benefits. The resulting mixture tuned clutter matched filter (MT-CMF) shows effective performance on simulated and airborne datasets. The classical MNF transform was applied, followed by k-means clustering. Then, each cluster s mean, covariance, and the corresponding eigenvalues were estimated. This yields a cluster-specific matched filter estimate as well as a cluster- specific feasibility score to flag outlier false positives. The technology described is a proof of concept that may be employed in future target detection and mapping applications for remote imaging spectrometers. It is of most direct relevance to JPL proposals for airborne and orbital hyperspectral instruments. Applications include subpixel target detection in hyperspectral scenes for military surveillance. Earth science applications include mineralogical mapping, species discrimination for ecosystem health monitoring, and land use classification.

Girls’ Disruptive Behavior and its Relationship to Family Functioning: A Review

PubMed Central

Kroneman, Leoniek M.; Loeber, Rolf; Hipwell, Alison E.; Koot, Hans M.

2009-01-01

Although a number of reviews of gender differences in disruptive behavior and parental socialization exist, we extend this literature by addressing the question of differential development among girls and by placing both disruptive behavior and parenting behavior in a developmental framework. Clarifying the heterogeneity of development in girls is important for developing and optimizing gender-specific prevention and treatment programs. In the current review, we describe the unique aspects of the development of disruptive behavior in girls and explore how the gender-specific development of disruptive behavior can be explained by family linked risk and protective processes. Based on this review, we formulate a gender-specific reciprocal model of the influence of social factors on the development of disruptive behavior in girls in order to steer further research and better inform prevention and treatment programs. PMID:20161077

Specific aspects of cognitive and language proficiency account for variability in neural indices of semantic and syntactic processing in children.

PubMed

Hampton Wray, Amanda; Weber-Fox, Christine

2013-07-01

The neural activity mediating language processing in young children is characterized by large individual variability that is likely related in part to individual strengths and weakness across various cognitive abilities. The current study addresses the following question: How does proficiency in specific cognitive and language functions impact neural indices mediating language processing in children? Thirty typically developing seven- and eight-year-olds were divided into high-normal and low-normal proficiency groups based on performance on nonverbal IQ, auditory word recall, and grammatical morphology tests. Event-related brain potentials (ERPs) were elicited by semantic anomalies and phrase structure violations in naturally spoken sentences. The proficiency for each of the specific cognitive and language tasks uniquely contributed to specific aspects (e.g., timing and/or resource allocation) of neural indices underlying semantic (N400) and syntactic (P600) processing. These results suggest that distinct aptitudes within broader domains of cognition and language, even within the normal range, influence the neural signatures of semantic and syntactic processing. Furthermore, the current findings have important implications for the design and interpretation of developmental studies of ERPs indexing language processing, and they highlight the need to take into account cognitive abilities both within and outside the classic language domain. Copyright © 2013 Elsevier Ltd. All rights reserved.

Multisatellite constellation configuration selection for multiregional highly elliptical orbit constellations

NASA Technical Reports Server (NTRS)

Matossian, Mark G.

1994-01-01

The Archimedes Project is a joint effort of the European Space Agency (ESA) and the National Space Development Agency of Japan (NASDA). The primary goal of the Archimedes project is to perform a technical feasibility analysis and preliminary design of a highly inclined multisatellite constellation for direct broadcast and mobile communications services for Europe, Japan and much of North America. This report addresses one aspect of this project, specifically an analysis of continuous satellite coverage using multiregional highly elliptical orbits (M-HEO's). The analysis methodology and ensuing software tool, named SPIFF, were developed specifically for this project by the author during the summer of 1992 under the STA/NSF Summer Institute in Japan Program at Tsukuba Space Center.

Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases.

PubMed

Zhao, Hong; Jin, Guangxu; Cui, Kemi; Ren, Ding; Liu, Timothy; Chen, Peikai; Wong, Solomon; Li, Fuhai; Fan, Yubo; Rodriguez, Angel; Chang, Jenny; Wong, Stephen T C

2013-10-15

A new type of signaling network element, called cancer signaling bridges (CSB), has been shown to have the potential for systematic and fast-tracked drug repositioning. On the basis of CSBs, we developed a computational model to derive specific downstream signaling pathways that reveal previously unknown target-disease connections and new mechanisms for specific cancer subtypes. The model enables us to reposition drugs based on available patient gene expression data. We applied this model to repurpose known or shelved drugs for brain, lung, and bone metastases of breast cancer with the hypothesis that cancer subtypes have their own specific signaling mechanisms. To test the hypothesis, we addressed specific CSBs for each metastasis that satisfy (i) CSB proteins are activated by the maximal number of enriched signaling pathways specific to a given metastasis, and (ii) CSB proteins are involved in the most differential expressed coding genes specific to each breast cancer metastasis. The identified signaling networks for the three types of breast cancer metastases contain 31, 15, and 18 proteins and are used to reposition 15, 9, and 2 drug candidates for the brain, lung, and bone metastases. We conducted both in vitro and in vivo preclinical experiments as well as analysis on patient tumor specimens to evaluate the targets and repositioned drugs. Of special note, we found that the Food and Drug Administration-approved drugs, sunitinib and dasatinib, prohibit brain metastases derived from breast cancer, addressing one particularly challenging aspect of this disease. ©2013 AACR.

Counterfeit deterrence and digital imaging technology

NASA Astrophysics Data System (ADS)

Church, Sara E.; Fuller, Reese H.; Jaffe, Annette B.; Pagano, Lorelei W.

2000-04-01

The US government recognizes the growing problem of counterfeiting currency using digital imaging technology, as desktop systems become more sophisticated, less expensive and more prevalent. As the rate of counterfeiting with this type of equipment has grown, the need for specific prevention methods has become apparent to the banknote authorities. As a result, the Treasury Department and Federal Reserve have begun to address issues related specifically to this type of counterfeiting. The technical representatives of these agencies are taking a comprehensive approach to minimize counterfeiting using digital technology. This approach includes identification of current technology solutions for banknote recognition, data stream intervention and output marking, outreach to the hardware and software industries and enhancement of public education efforts. Other aspects include strong support and cooperation with existing international efforts to prevent counterfeiting, review and amendment of existing anti- counterfeiting legislation and investigation of currency design techniques to make faithful reproduction more difficult. Implementation of these steps and others are to lead to establishment of a formal, permanent policy to address and prevent the use of emerging technologies to counterfeit currency.

Total Pancreatectomy With Islet Auto-Transplantation (TPIAT): Summary of an NIDDK Workshop

PubMed Central

Bellin, Melena D.; Gelrud, Andres; Arreaza-Rubin, Guillermo; Dunn, Ty B.; Humar, Abhinav; Morgan, Katherine A.; Naziruddin, Bashoo; Rastellini, Cristiana; Rickels, Michael R.; Schwarzenberg, Sarah J.; Andersen, Dana K.

2014-01-01

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) focused on research gaps and opportunities in total pancreatectomy with islet autotransplantation (TPIAT) for the management of chronic pancreatitis (CP). The session was held on July 23, 2014 and structured into five sessions: (1) patient selection, indications, and timing; (2) technical aspects of TPIAT; (3) improving success of islet autotransplantation; (4) improving outcomes after total pancreatectomy; and (5) registry considerations for TPIAT. The current state of knowledge was reviewed; knowledge gaps and research needs were specifically highlighted. Common themes included the need to identify which patients best benefit from and when to intervene with TPIAT, current limitations of the surgical procedure, diabetes remission and the potential for improvement, opportunities to better address pain remission, GI complications in this population, and unique features of children with CP considered for TPIAT. The need for a multicenter patient registry that specifically addresses the complexities of CP and total pancreatectomy outcomes as well as post-surgical diabetes outcomes was repeatedly emphasized. PMID:25333399

Competition Between Transients in the Rate of Approach to a Fixed Point

NASA Astrophysics Data System (ADS)

Day, Judy; Rubin, Jonathan E.; Chow, Carson C.

2009-01-01

The goal of this paper is to provide and apply tools for analyzing a specific aspect of transient dynamics not covered by previous theory. The question we address is whether one component of a perturbed solution to a system of differential equations can overtake the corresponding component of a reference solution as both converge to a stable node at the origin, given that the perturbed solution was initially farther away and that both solutions are nonnegative for all time. We call this phenomenon tolerance, for its relation to a biological effect. We show using geometric arguments that tolerance will exist in generic linear systems with a complete set of eigenvectors and in excitable nonlinear systems. We also define a notion of inhibition that may constrain the regions in phase space where the possibility of tolerance arises in general systems. However, these general existence theorems do not not yield an assessment of tolerance for specific initial conditions. To address that issue, we develop some analytical tools for determining if particular perturbed and reference solution initial conditions will exhibit tolerance.

The Association Between Sexual Health and Physical, Mental, and Social Health in Adolescent Women.

PubMed

Hensel, Devon J; Nance, Jennifer; Fortenberry, J Dennis

2016-10-01

Developmental models link sexual well-being to physical, mental/emotional, and social well-being, yet little empirical literature evaluates these relationships in adolescents. Better understanding of how and when sexuality complements other aspects of health may yield important points to enhance existing health education and prevention efforts. Data were drawn from a 10-year longitudinal cohort study of sexual relationships and sexual behavior among adolescent women (N = 387; 14-17 years at enrollment). Sexual health data were drawn from quarterly partner-specific interviews and were linked to physical, mental/emotional, and social health information in annual questionnaires. Random intercept, mixed effects linear, ordinal logistic, or binary logistic regression were used to estimate the influence of sexual health on health and well-being outcomes (Stata, v.23, StataCorp, College Station, TX). All models controlled for participant age and race/ethnicity. Higher sexual health was significantly associated with less frequent nicotine and substance use, lower self-reported depression, lower thrill seeking, higher self-esteem, having fewer friends who use substances, higher religiosity, better social integration, lower frequency of delinquent behavior and crime, and more frequent community group membership. Sexual health was not associated with the number of friends who used cigarettes. Positive sexually related experiences in romantic relationships during adolescence may complement physical, mental/emotional, and social health. Addressing specific aspects of healthy sexual development during clinical encounters could dually help primary prevention and health education address other common adolescent health issues. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Managing patients with encephalitis.

PubMed

Matata, Claire; Easton, Ava; Michael, Benedict; Evans, Becky; Ward, Deborah; Solomon, Tom; Kneen, Rachel

2015-11-11

This article provides an overview of encephalitis and addresses its diagnosis, some of the common presenting signs and symptoms, and the different aspects of nursing care required for these patients. In particular, it addresses how to explain encephalitis to the patient's relatives, the rehabilitation needs of these patients, and important aspects of discharge planning. Tests that are necessary for diagnosis in patients with suspected encephalitis and the importance of these are explained.

Comet assay: an essential tool in toxicological research.

PubMed

Glei, M; Schneider, T; Schlörmann, W

2016-10-01

The comet assay is a versatile, reliable, cost-efficient, and fast technique for detecting DNA damage and repair in any tissue. It is useable in almost any cell type and applicable to both eukaryotic and prokaryotic organisms. Instead of highlighting one of the numerous specific aspects of the comet assay, the present review aims at giving an overview about the evolution of this widely applicable method from the first description by Ostling and Johanson to the OECD Guideline 489 for the in vivo mammalian comet assay. In addition, methodical aspects and the influence of critical steps of the assay as well as the evaluation of results and improvements of the method are reviewed. Methodical aspects regarding oxidative DNA damage and repair are also addressed. An overview about the most recent works and relevant cutting-edge reviews based on the comet assay with special regard to, e.g., clinical applications, nanoparticles or environmental risk assessment concludes this review. Taken together, the presented overview raises expectations to further decades of successful applications and enhancements of this excellent method.

Non parametric, self organizing, scalable modeling of spatiotemporal inputs: the sign language paradigm.

PubMed

Caridakis, G; Karpouzis, K; Drosopoulos, A; Kollias, S

2012-12-01

Modeling and recognizing spatiotemporal, as opposed to static input, is a challenging task since it incorporates input dynamics as part of the problem. The vast majority of existing methods tackle the problem as an extension of the static counterpart, using dynamics, such as input derivatives, at feature level and adopting artificial intelligence and machine learning techniques originally designed for solving problems that do not specifically address the temporal aspect. The proposed approach deals with temporal and spatial aspects of the spatiotemporal domain in a discriminative as well as coupling manner. Self Organizing Maps (SOM) model the spatial aspect of the problem and Markov models its temporal counterpart. Incorporation of adjacency, both in training and classification, enhances the overall architecture with robustness and adaptability. The proposed scheme is validated both theoretically, through an error propagation study, and experimentally, on the recognition of individual signs, performed by different, native Greek Sign Language users. Results illustrate the architecture's superiority when compared to Hidden Markov Model techniques and variations both in terms of classification performance and computational cost. Copyright © 2012 Elsevier Ltd. All rights reserved.

Experimental Models of Ocular Infection with Toxoplasma Gondii

PubMed Central

Dukaczewska, Agata; Tedesco, Roberto; Liesenfeld, Oliver

2015-01-01

Ocular toxoplasmosis is a vision-threatening disease and the major cause of posterior uveitis worldwide. In spite of the continuing global burden of ocular toxoplasmosis, many critical aspects of disease including the therapeutic approach to ocular toxoplasmosis are still under debate. To assist in addressing many aspects of the disease, numerous experimental models of ocular toxoplasmosis have been established. In this article, we present an overview on in vitro, ex vivo, and in vivo models of ocular toxoplasmosis available to date. Experimental studies on ocular toxoplasmosis have recently focused on mice. However, the majority of murine models established so far are based on intraperitoneal and intraocular infection with Toxoplasma gondii. We therefore also present results obtained in an in vivo model using peroral infection of C57BL/6 and NMRI mice that reflects the natural route of infection and mimics the disease course in humans. While advances have been made in ex vivo model systems or larger animals to investigate specific aspects of ocular toxoplasmosis, laboratory mice continue to be the experimental model of choice for the investigation of ocular toxoplasmosis. PMID:26716018

Visual Communication in Web Design - Analyzing Visual Communication in Web Design

NASA Astrophysics Data System (ADS)

Thorlacius, Lisbeth

Web sites are rapidly becoming the preferred media choice for information search, company presentation, shopping, entertainment, education, and social contacts. And along with the various forms of communication that the Web offers the aesthetic aspects have begun to play an increasingly important role. However, studies in the design and the relevance of focusing on the aesthetic aspects in planning and using Web sites have only to a smaller degree been subject of theoretical reflection. For example, Miller (2000), Thorlacius (2001, 2002, 2005), Engholm (2002, 2003), and Beaird (2007) have been contributing to set a beginning agenda that address the aesthetic aspects. On the other hand, there is a considerable amount of literature addressing the theoretical and methodological aspects focusing on the technical and functional aspects. In this context it is the aim of this article to introduce a model for analysis of visual communication on websites.

Fabrication aspects of PLA-CaP/PLGA-CaP composites for orthopedic applications: a review.

PubMed

Zhou, Huan; Lawrence, Joseph G; Bhaduri, Sarit B

2012-07-01

For several decades, composites made of polylactic acid-calcium phosphates (PLA-CaP) and polylactic acid-co-glycolic acid-calcium phosphates (PLGA-CaP) have seen widespread uses in orthopedic applications. This paper reviews the fabrication aspects of these composites, following the ubiquitous materials science approach by studying "processing-structure-property" correlations. Various fabrication processes such as microencapsulation, phase separation, electrospinning, supercritical gas foaming, etc., are reviewed, with specific examples of their applications in fabricating these composites. The effect of the incorporation of CaP materials on the mechanical and biological performance of PLA/PLGA is addressed. In addition, this paper describes the state of the art on challenges and innovations concerning CaP dispersion, incorporation of biomolecules/stem cells and long-term degradation of the composites. Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

A normative analysis of nursing knowledge.

PubMed

Zanotti, Renzo; Chiffi, Daniele

2016-03-01

This study addresses the question of normative analysis of the value-based aspects of nursing. In our perspective, values in science may be distinguished into (i) epistemic when related to the goals of truth and objectivity and (ii) non-epistemic when related to social, cultural or political aspects. Furthermore, values can be called constitutive when necessary for a scientific enterprise, or contextual when contingently associated with science. Analysis of the roles of the various forms of values and models of knowledge translation provides the ground to understand the specific role of values in nursing. A conceptual framework has been built to classify some of the classical perspectives on nursing knowledge and to examine the relationships between values and different forms of knowledge in nursing. It follows that adopting a normative perspective in the analysis of nursing knowledge provides key elements to identify its proper dimension. © 2015 John Wiley & Sons Ltd.

A new quality of bone ultrasound research.

PubMed

Gluer, C C

2008-07-01

Quantitative ultrasound (QUS) methods have strong power to predict osteoporotic fractures, but they are also very relevant for the assessment of bone quality. A representative sample of recent studies addressing these topics can be found in this special issue. Further pursuit of these methods will establish micro-QUS imaging methods as tools for measuring specific aspects of bone quality. Once this is achieved, we will be able to link such data to the clinical QUS methods used in vivo to determine which aspects of bone quality cause QUS to be a predictor of fracture risk that is independent of bone mineral density (BMD). Potentially this could lead to the development of a new generation of QUS devices for improved and expanded clinical assessment. Good quality of basic science work will thus lead to good quality of clinical patient examinations on the basis of a more detailed assessment of bone quality.

Money Matters: Recommendations for Financial Stress Research in Occupational Health Psychology.

PubMed

Sinclair, Robert R; Cheung, Janelle H

2016-08-01

Money is arguably the most important resource derived from work and the most important source of stress for contemporary employees. A substantial body of research supports the relationship between access to financial resources and health and well-being, both at individual and aggregated (e.g. national) levels of analysis. Yet, surprisingly little occupational health psychology research has paid attention to financial issues experienced specifically by those in the labour force. With these issues in mind, the overarching goal of the present paper was to address conceptual and measurement issues in the study of objective and subjective aspects of financial stress and review several assessment options available to occupational health psychology researchers for both aspects of financial stress. Where appropriate, we offer guidance to researchers about choices among various financial stress measures and identify issues that require further research attention. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Medical technology at home: safety-related items in technical documentation.

PubMed

Hilbers, Ellen S M; de Vries, Claudette G J C A; Geertsma, Robert E

2013-01-01

This study aimed to investigate the technical documentation of manufacturers on issues of safe use of their device in a home setting. Three categories of equipment were selected: infusion pumps, ventilators, and dialysis systems. Risk analyses, instructions for use, labels, and post market surveillance procedures were requested from manufacturers. Additionally, they were asked to fill out a questionnaire on collection of field experience, on incidents, and training activities. Specific risks of device operation by lay users in a home setting were incompletely addressed in the risk analyses. A substantial number of user manuals were designed for professionals, rather than for patients or lay carers. Risk analyses and user information often showed incomplete coherence. Post market surveillance was mainly based on passive collection of field experiences. Manufacturers of infusion pumps, ventilators, and dialysis systems pay insufficient attention to the specific risks of use by lay persons in home settings. It is expected that this conclusion is also applicable for other medical equipment for treatment at home. Manufacturers of medical equipment for home use should pay more attention to use errors, lay use and home-specific risks in design, risk analysis, and user information. Field experiences should be collected more actively. Coherence between risk analysis and user information should be improved. Notified bodies should address these aspects in their assessment. User manuals issued by institutions supervising a specific home therapy should be drawn up in consultation with the manufacturer.

Physically corrected forward operators for induced emission tomography: a simulation study

NASA Astrophysics Data System (ADS)

Viganò, Nicola Roberto; Solé, Vicente Armando

2018-03-01

X-ray emission tomography techniques over non-radioactive materials allow one to investigate different and important aspects of the matter that are usually not addressable with the standard x-ray transmission tomography, such as density, chemical composition and crystallographic information. However, the quantitative reconstruction of these investigated properties is hindered by additional problems, including the self-attenuation of the emitted radiation. Work has been done in the past, especially concerning x-ray fluorescence tomography, but this has always focused on solving very specific problems. The novelty of this work resides in addressing the problem of induced emission tomography from a much wider perspective, introducing a unified discrete representation that can be used to modify existing algorithms to reconstruct the data of the different types of experiments. The direct outcome is a clear and easy mathematical description of the implementation details of such algorithms, despite small differences in geometry and other practical aspects, but also the possibility to express the reconstruction as a minimization problem, allowing the use of variational methods, and a more flexible modeling of the noise involved in the detection process. In addition, we look at the results of a few selected simulated data reconstructions that describe the effect of physical corrections like the self-attenuation, and the response to noise of the adapted reconstruction algorithms.

High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics

PubMed Central

Carvalho, Carlos M.; Chang, Jeffrey; Lucas, Joseph E.; Nevins, Joseph R.; Wang, Quanli; West, Mike

2010-01-01

We describe studies in molecular profiling and biological pathway analysis that use sparse latent factor and regression models for microarray gene expression data. We discuss breast cancer applications and key aspects of the modeling and computational methodology. Our case studies aim to investigate and characterize heterogeneity of structure related to specific oncogenic pathways, as well as links between aggregate patterns in gene expression profiles and clinical biomarkers. Based on the metaphor of statistically derived “factors” as representing biological “subpathway” structure, we explore the decomposition of fitted sparse factor models into pathway subcomponents and investigate how these components overlay multiple aspects of known biological activity. Our methodology is based on sparsity modeling of multivariate regression, ANOVA, and latent factor models, as well as a class of models that combines all components. Hierarchical sparsity priors address questions of dimension reduction and multiple comparisons, as well as scalability of the methodology. The models include practically relevant non-Gaussian/nonparametric components for latent structure, underlying often quite complex non-Gaussianity in multivariate expression patterns. Model search and fitting are addressed through stochastic simulation and evolutionary stochastic search methods that are exemplified in the oncogenic pathway studies. Supplementary supporting material provides more details of the applications, as well as examples of the use of freely available software tools for implementing the methodology. PMID:21218139

Alternative Method to Simulate a Sub-idle Engine Operation in Order to Synthesize Its Control System

NASA Astrophysics Data System (ADS)

Sukhovii, Sergii I.; Sirenko, Feliks F.; Yepifanov, Sergiy V.; Loboda, Igor

2016-09-01

The steady-state and transient engine performances in control systems are usually evaluated by applying thermodynamic engine models. Most models operate between the idle and maximum power points, only recently, they sometimes address a sub-idle operating range. The lack of information about the component maps at the sub-idle modes presents a challenging problem. A common method to cope with the problem is to extrapolate the component performances to the sub-idle range. Precise extrapolation is also a challenge. As a rule, many scientists concern only particular aspects of the problem such as the lighting combustion chamber or the turbine operation under the turned-off conditions of the combustion chamber. However, there are no reports about a model that considers all of these aspects and simulates the engine starting. The proposed paper addresses a new method to simulate the starting. The method substitutes the non-linear thermodynamic model with a linear dynamic model, which is supplemented with a simplified static model. The latter model is the set of direct relations between parameters that are used in the control algorithms instead of commonly used component performances. Specifically, this model consists of simplified relations between the gas path parameters and the corrected rotational speed.

Multichannel/Multisensor Signal Processing In Uncertain Environments With Application To Multitarget Tracking.

DTIC Science & Technology

1998-05-22

NUMBER PR-98-1 T. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Office of Naval Research Ballston Center Tower One One North Quincy...unlimited. 12 b. DISTRIBUTION CODE 19980601 082 13. ABSTRACT (Maximum 200 words) This research project is concerned with two distinct aspects of analysis...Environments With Application To Multitarget Tracking This research project is concerned with two distinct aspects of analysis and processing of sig

Method and apparatus for monitoring plasma processing operations

DOEpatents

Smith, Jr., Michael Lane; Ward, Pamela Denise Peardon; Stevenson, Joel O'Don

2002-01-01

The invention generally relates to various aspects of a plasma process, and more specifically the monitoring of such plasma processes. One aspect relates in at least some manner to calibrating or initializing a plasma monitoring assembly. This type of calibration may be used to address wavelength shifts, intensity shifts, or both associated with optical emissions data obtained on a plasma process. A calibration light may be directed at a window through which optical emissions data is being obtained to determine the effect, if any, that the inner surface of the window is having on the optical emissions data being obtained therethrough, the operation of the optical emissions data gathering device, or both. Another aspect relates in at least some manner to various types of evaluations which may be undertaken of a plasma process which was run, and more typically one which is currently being run, within the processing chamber. Plasma health evaluations and process identification through optical emissions analysis are included in this aspect. Yet another aspect associated with the present invention relates in at least some manner to the endpoint of a plasma process (e.g., plasma recipe, plasma clean, conditioning wafer operation) or discrete/discernible portion thereof (e.g., a plasma step of a multiple step plasma recipe). Another aspect associated with the present invention relates to how one or more of the above-noted aspects may be implemented into a semiconductor fabrication facility, such as the distribution of wafers to a wafer production system. A final aspect of the present invention relates to a network a plurality of plasma monitoring systems, including with remote capabilities (i.e., outside of the clean room).

Masculinity and HIV: Dimensions of Masculine Norms that Contribute to Men's HIV-Related Sexual Behaviors.

PubMed

Fleming, Paul J; DiClemente, Ralph J; Barrington, Clare

2016-04-01

Numerous studies have documented a relationship between masculine norms and men's HIV-related sexual behaviors, but intervening upon this relationship requires a nuanced understanding of the specific aspects of masculine norms that shape men's sexual behaviors. We integrate theories on masculinities with empirical HIV research to identify specific dimensions of masculine norms that influence men's HIV-related sexual behaviors. We identify three major dimensions of masculine norms that shape men's sexual behavior: (1) uncontrollable male sex drive, (2) capacity to perform sexually, and (3) power over others. While the existing literature does help explain the relationship between masculine norms and men's sexual behaviors several gaps remain including: a recognition of context-specific masculinities, an interrogation of the positive influences of masculinity, adoption of an intersectional approach, assessment of changes in norms and behaviors over time, and rigorous evaluations of gender-transformative approaches. Addressing these gaps in future research may optimize prevention efforts.

The Neuropsychology of Amphetamine and Opiate Dependence: Implications for Treatment

PubMed Central

Sahakian, Barbara J

2013-01-01

Chronic use of amphetamines and/or opiates has been associated with a wide range of cognitive deficits, involving domains of attention, inhibitory control, planning, decision-making, learning and memory. Although both amphetamine and opiate users show marked impairment in various aspects of cognitive function, the impairment profile is distinctly different according to the substance of abuse. In light of evidence showing that cognitive impairment in drug users has a negative impact on treatment engagement and efficacy, we review substance-specific deficits on executive and memory function, and discuss possibilities to address these during treatment intervention. PMID:17690986

Performing Verification and Validation in Reuse-Based Software Engineering

NASA Technical Reports Server (NTRS)

Addy, Edward A.

1999-01-01

The implementation of reuse-based software engineering not only introduces new activities to the software development process, such as domain analysis and domain modeling, it also impacts other aspects of software engineering. Other areas of software engineering that are affected include Configuration Management, Testing, Quality Control, and Verification and Validation (V&V). Activities in each of these areas must be adapted to address the entire domain or product line rather than a specific application system. This paper discusses changes and enhancements to the V&V process, in order to adapt V&V to reuse-based software engineering.

Multiple Determinants, Common Vulnerabilities, and Creative Responses: Addressing the AIDS Pandemic in Diverse Populations Globally

PubMed Central

Mayer, Kenneth H.; Pape, Jean William; Wilson, Phill; Diallo, Dazon Dixon; Saavedra, Jorge; Mimiaga, Matthew J.; Koenig, Serena; Farmer, Paul

2012-01-01

The AIDS epidemic has been fueled by global inequities. Ranging from gender inequality and underdevelopment to homophobia impeding health care access for men who have sex with men (MSM), imbalanced resource allocations and social biases have potentiated the epidemic’s spread. However, recognition of culturally specific aspects of each microepidemic has yielded development of community-based organizations, which have resulted in locally effective responses to AIDS. This effective approach to HIV prevention, care and treatment is illustrated through examples of community-based responses in Haiti, the United States, Africa, and other impoverished settings. PMID:22772387

Organizational change tactics: the evidence base in the literature.

PubMed

Packard, Thomas; Shih, Amber

2014-01-01

Planned organizational change processes can be used to address the many challenges facing human service organizations (HSOs) and improve organizational outcomes. There is massive literature on organizational change, ranging from popular management books to academic research on specific aspects of change. Regarding HSOs, there is a growing literature, including increasing attention to implementation science and evidence-based practices. However, research which offers generalizable, evidence-based guidelines for implementing change is not common. The purpose of the authors was to assess the evidence base in this organizational change literature to lay the groundwork for more systematic knowledge development in this important field.

Teaching Psychology: The Political Context

ERIC Educational Resources Information Center

Newland, John

2008-01-01

In this commentary, the author raises two critical aspects not adequately addressed in John Radford's (2008) wide ranging article on the teaching of psychology in higher education. The first aspect is the relevance of boundaries. The second aspect is the political context(s). These two issues, though artificially dissociated for current purposes,…

Bedside Manner and Effective Academic Administrative Leadership

ERIC Educational Resources Information Center

Gilley, Daryl

2003-01-01

In this chapter, the author addresses one small aspect of the leadership algorithm: communication. As the title suggests, the aspect of communication he discusses is that nebulous part of the human interaction process that sets the stage--the one that results in creative problem solving and collegial relationships--the interpersonal aspects of…

Language for Winning Hearts and Minds: Verb Aspect in U.S. Presidential Campaign Speeches for Engaging Emotion.

PubMed

Havas, David A; Chapp, Christopher B

2016-01-01

How does language influence the emotions and actions of large audiences? Functionally, emotions help address environmental uncertainty by constraining the body to support adaptive responses and social coordination. We propose emotions provide a similar function in language processing by constraining the mental simulation of language content to facilitate comprehension, and to foster alignment of mental states in message recipients. Consequently, we predicted that emotion-inducing language should be found in speeches specifically designed to create audience alignment - stump speeches of United States presidential candidates. We focused on phrases in the past imperfective verb aspect ("a bad economy was burdening us") that leave a mental simulation of the language content open-ended, and thus unconstrained, relative to past perfective sentences ("we were burdened by a bad economy"). As predicted, imperfective phrases appeared more frequently in stump versus comparison speeches, relative to perfective phrases. In a subsequent experiment, participants rated phrases from presidential speeches as more emotionally intense when written in the imperfective aspect compared to the same phrases written in the perfective aspect, particularly for sentences perceived as negative in valence. These findings are consistent with the notion that emotions have a role in constraining the comprehension of language, a role that may be used in communication with large audiences.

Construction of optimal 3-node plate bending triangles by templates

NASA Astrophysics Data System (ADS)

Felippa, C. A.; Militello, C.

A finite element template is a parametrized algebraic form that reduces to specific finite elements by setting numerical values to the free parameters. The present study concerns Kirchhoff Plate-Bending Triangles (KPT) with 3 nodes and 9 degrees of freedom. A 37-parameter template is constructed using the Assumed Natural Deviatoric Strain (ANDES). Specialization of this template includes well known elements such as DKT and HCT. The question addressed here is: can these parameters be selected to produce high performance elements? The study is carried out by staged application of constraints on the free parameters. The first stage produces element families satisfying invariance and aspect ratio insensitivity conditions. Application of energy balance constraints produces specific elements. The performance of such elements in benchmark tests is presently under study.

Evaluation of the Geotech SMART24BH 20Vpp/5Vpp data acquisition system with active fortezza crypto card data signing and authentication.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rembold, Randy Kai; Hart, Darren M.

Sandia National Laboratories has tested and evaluated Geotech SMART24BH borehole data acquisition system with active Fortezza crypto card data signing and authentication. The test results included in this report were in response to static and tonal-dynamic input signals. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and 1241 for Analog to Digital Converters; others were designed by Sandia specifically for infrasound application evaluation and for supplementary criteria not addressed in the IEEE standards. The objective of this work was to evaluate the overall technical performance of two Geotech SMART24BH digitizers with a Fortezza PCMCIAmore » crypto card actively implementing the signing of data packets. The results of this evaluation were compared to relevant specifications provided within manufacturer's documentation notes. The tests performed were chosen to demonstrate different performance aspects of the digitizer under test. The performance aspects tested include determining noise floor, least significant bit (LSB), dynamic range, cross-talk, relative channel-to-channel timing, time-tag accuracy/statistics/drift, analog bandwidth.« less

A Multiple Case Study of Mental Health Interventions in Middle Income Countries: Considering the Science of Delivery

PubMed Central

Cole, Donald C.; Muskat, Elisha; Raja, Shoba; Wiljer, David; Aylward, David

2016-01-01

In the debate in global mental health about the most effective models for developing and scaling interventions, there have been calls for the development of a more robust literature regarding the "non-specific", science of delivery aspects of interventions that are locally, contextually, and culturally relevant. This study describes a rigorous, exploratory, qualitative examination of the key, non-specific intervention strategies of a diverse group of five internationally-recognized organizations addressing mental illness in middle income countries (MICs). A triangulated approach to inquiry was used with semi-structured interviews conducted with service recipients, service providers and leaders, and key community partners (N = 159). The interview focus was upon processes of implementation and operation. A grounded theory-informed analysis revealed cross cutting themes of: a holistic conceptualization of mental health problems, an intensive application of principles of leverage and creating the social, cultural, and policy “space” within which interventions could be applied and resourced. These findings aligned with key aspects of systems dynamic theory suggesting that it might be a helpful framework in future studies of mental health service implementation in MICs. PMID:27011053

Use of wildlife webcams - Literature review and annotated bibliography

USGS Publications Warehouse

Ratz, Joan M.; Conk, Shannon J.

2010-01-01

The U.S. Fish and Wildlife Service National Conservation Training Center requested a literature review product that would serve as a resource to natural resource professionals interested in using webcams to connect people with nature. The literature review focused on the effects on the public of viewing wildlife through webcams and on information regarding installation and use of webcams. We searched the peer reviewed, published literature for three topics: wildlife cameras, virtual tourism, and technological nature. Very few publications directly addressed the effect of viewing wildlife webcams. The review of information on installation and use of cameras yielded information about many aspects of the use of remote photography, but not much specifically regarding webcams. Aspects of wildlife camera use covered in the literature review include: camera options, image retrieval, system maintenance and monitoring, time to assemble, power source, light source, camera mount, frequency of image recording, consequences for animals, and equipment security. Webcam technology is relatively new and more publication regarding the use of the technology is needed. Future research should specifically study the effect that viewing wildlife through webcams has on the viewers' conservation attitudes, behaviors, and sense of connectedness to nature.

Forming impressions of facial attractiveness is mandatory.

PubMed

Ritchie, Kay L; Palermo, Romina; Rhodes, Gillian

2017-03-28

First impressions of social traits, such as attractiveness, from faces are often claimed to be made automatically, given their speed and reliability. However, speed of processing is only one aspect of automaticity. Here we address a further aspect, asking whether impression formation is mandatory. Mandatory formation requires that impressions are formed about social traits even when this is task-irrelevant, and that once formed, these impressions are difficult to inhibit. In two experiments, participants learned what new people looked like for the purpose of future identification, from sets of images high or low in attractiveness. They then rated middle-attractiveness images of each person, for attractiveness. Even though instructed to rate the specific images, not the people, their ratings were biased by the attractiveness of the learned images. A third control experiment, with participants rating names, demonstrated that participants in Experiments 1 and 2 were not simply rating the people, rather than the specific images as instructed. These results show that the formation of attractiveness impressions from faces is mandatory, thus broadening the evidence for automaticity of facial impressions. The mandatory formation of impressions is likely to have an important impact in real-world situations such as online dating sites.

Using sociodrama and psychodrama to teach communication in end-of-life care.

PubMed

Baile, Walter F; De Panfilis, Ludovica; Tanzi, Silvia; Moroni, Matteo; Walters, Rebecca; Biasco, Guido

2012-09-01

End-of-life discussions can be stressful and can elicit strong emotions in the provider as well as the patient and family. In palliative care, understanding and effectively addressing emotions is a key skill that can enhance professional competency and patient/family satisfaction with care. We illustrate how in coursework for a Master's degree in palliative medicine we used dramatic "action methods" derived from sociodrama and psychodrama in the portrayal of two challenging cases to train providers in the emotional aspects of caring for patients with advanced cancer. We describe the specific techniques of constructing and enacting case scenarios using warm-ups, role-creation, doubling and role-reversal. In particular, we illustrate how these techniques and others were used to reveal and address the "hidden" emotions, attitudes, and values that were central to the communication dilemma. Finally, we present an evaluation completed by the 26 participants who attended the course.

Engagement practices that join scientific methods with community wisdom: Designing a patient-centered, randomized control trial with a Pacific Islander Community

PubMed Central

Goulden, Peter A.; Bursac, Zoran; Hudson, Jonell; Purvis, Rachel S.; Yeary, Karen H. Kim; Aitaoto, Nia; Kohler, Peter O.

2016-01-01

This article illustrates how a collaborative research process can successfully engage an underserved minority community to address health disparities. Pacific Islanders, including the Marshallese, are one of the fastest growing US populations. They face significant health disparities, including extremely high rates of type 2 diabetes. This article describes the engagement process of designing patient-centered outcomes research with Marshallese stakeholders, highlighting the specific influences of their input on a randomized control trial to address diabetes. Over 18 months, an interdisciplinary research team used community-based participatory principles to conduct patient-engaged outcomes research that involved 31 stakeholders in all aspects of research design, from defining the research question to making decisions about budgets and staffing. This required academic researcher flexibility, but yielded a design linking scientific methodology with community wisdom. PMID:27325179

Do Supplemental Remedial Reading Programs Address the Motivational Issues of Struggling Readers? An Analysis of Five Popular Programs.

PubMed

Quirk, Matthew P; Schwanenflugel, Paula J

2004-04-01

Five popular, but distinctly different, remedial reading programs were reviewed regarding the potential to motivate children to read. It is argued that current remedial reading program designs and research on program effectiveness ignore the impact that motivation has on struggling readers. In addition, we develop a theory of reading motivation specific to struggling readers that highlights motivational constructs we feel are important to the improvement of reading skill for this population of students. The three aspects of reading motivation most relevant to the instruction of remedial readers include: (a) improving reading self-efficacy; (b) making internal and controllable outcome attributions for successes and failures associated with reading; and (c) establishing personally relevant value in becoming a better reader. We conclude that, while most programs address some motivational issues and other issues not at all, most programs could make minor modifications that would greatly enhance their motivational impact.

Promoting active transportation as a partnership between urban planning and public health: the columbus healthy places program.

PubMed

Green, Christine Godward; Klein, Elizabeth G

2011-01-01

Active transportation has been considered as one method to address the American obesity epidemic. To address obesity prevention through built-environment change, the local public health department in Columbus, Ohio, established the Columbus Healthy Places (CHP) program to formally promote active transportation in numerous aspects of community design for the city. In this article, we present a case study of the CHP program and discuss the review of city development rezoning applications as a successful strategy to link public health to urban planning. Prior to the CHP review, 7% of development applications in Columbus included active transportation components; in 2009, 64% of development applications adopted active transportation components specifically recommended by the CHP review. Active transportation recommendations generally included adding bike racks, widening or adding sidewalks, and providing sidewalk connectivity. Recommendations and lessons learned from CHP are provided.

Neuroscience in Nigeria: the past, the present and the future.

PubMed

Balogun, Wasiu Gbolahan; Cobham, Ansa Emmanuel; Amin, Abdulbasit

2018-04-01

The science of the brain and nervous system cuts across almost all aspects of human life and is one of the fastest growing scientific fields worldwide. This necessitates the demand for pragmatic investment by all nations to ensure improved education and quality of research in Neurosciences. Although obvious efforts are being made in advancing the field in developed societies, there is limited data addressing the state of neuroscience in sub-Saharan Africa. Here, we review the state of neuroscience development in Nigeria, Africa's most populous country and its largest economy, critically evaluating the history, the current situation and future projections. This review specifically addresses trends in clinical and basic neuroscience research and education. We conclude by highlighting potentially helpful strategies that will catalyse development in neuroscience education and research in Nigeria, among which are an increase in research funding, provision of tools and equipment for training and research, and upgrading of the infrastructure at hand.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keyser, Matthew A

Present-day thermal management systems for battery electric vehicles are inadequate in limiting the maximum temperature rise of the battery during extreme fast charging. If the battery thermal management system is not designed correctly, the temperature of the cells could reach abuse temperatures and potentially send the cells into thermal runaway. Furthermore, the cell and battery interconnect design needs to be improved to meet the lifetime expectations of the consumer. Each of these aspects is explored and addressed as well as outlining where the heat is generated in a cell, the efficiencies of power and energy cells, and what type ofmore » battery thermal management solutions are available in today's market. Thermal management is not a limiting condition with regard to extreme fast charging, but many factors need to be addressed especially for future high specific energy density cells to meet U.S. Department of Energy cost and volume goals.« less

The State of Research on Communication and Literacy in Deafblindness.

PubMed

Bruce, Susan M; Nelson, Catherine; Perez, Angel; Stutzman, Brent; Barnhill, Brooke A

2016-01-01

In a synthesis of the research, the authors present findings from communication and literacy studies conducted with children and youth with deafblindness, ages 0-22 years, and published in peer-reviewed journals, 1990-2015. Findings are organized within the structure of the four aspects of communication: form, function, content, context. The studies implemented child-guided and systematic instructional approaches. Studies on form addressed tangible representations, gestures, pictures, and technologies to increase expressive communication rates, and included research focusing on specific functions. Most of the research on context addressed the coaching of adult communication partners to improve responsiveness. Research on communication by children who are deafblind has focused almost exclusively on improving expressive communication. Therefore, there is a need for research on receptive communication and comprehension. In the area of literacy, studies are needed on emergent literacy and reading and writing interventions for children who are deafblind.

Enabling fast charging - Battery thermal considerations

NASA Astrophysics Data System (ADS)

Keyser, Matthew; Pesaran, Ahmad; Li, Qibo; Santhanagopalan, Shriram; Smith, Kandler; Wood, Eric; Ahmed, Shabbir; Bloom, Ira; Dufek, Eric; Shirk, Matthew; Meintz, Andrew; Kreuzer, Cory; Michelbacher, Christopher; Burnham, Andrew; Stephens, Thomas; Francfort, James; Carlson, Barney; Zhang, Jiucai; Vijayagopal, Ram; Hardy, Keith; Dias, Fernando; Mohanpurkar, Manish; Scoffield, Don; Jansen, Andrew N.; Tanim, Tanvir; Markel, Anthony

2017-11-01

Battery thermal barriers are reviewed with regards to extreme fast charging. Present-day thermal management systems for battery electric vehicles are inadequate in limiting the maximum temperature rise of the battery during extreme fast charging. If the battery thermal management system is not designed correctly, the temperature of the cells could reach abuse temperatures and potentially send the cells into thermal runaway. Furthermore, the cell and battery interconnect design needs to be improved to meet the lifetime expectations of the consumer. Each of these aspects is explored and addressed as well as outlining where the heat is generated in a cell, the efficiencies of power and energy cells, and what type of battery thermal management solutions are available in today's market. Thermal management is not a limiting condition with regard to extreme fast charging, but many factors need to be addressed especially for future high specific energy density cells to meet U.S. Department of Energy cost and volume goals.

Cultural competency, autonomy, and spiritual conflicts related to Reiki/CAM therapies: Should patients be informed?

PubMed Central

Arvonio, Maria Marra

2014-01-01

The use of complementary and alternative medicines (CAM) such as Reiki is on the rise in healthcare centers. Reiki is associated with a spirituality that conflicts with some belief systems. Catholic healthcare facilities are restricted from offering this therapy because it conflicts with the teachings of the Catholic Church. However, hospitals are offering it without disclosing the spiritual aspects of it to patients. This article will address the ethical concerns and possible legal implications associated with the present process of offering Reiki. It will address these concerns based on the Joint Commission's Standard of Cultural Competency and the ethical principles of autonomy and informed consent. A proposal will also be introduced identifying specific information which Reiki/CAM practitioners should offer to their patients out of respect of their autonomy as well as their cultural, spiritual, and religious beliefs. PMID:24899738

Promoting Active Transportation as a Partnership Between Urban Planning and Public Health: The Columbus Healthy Places Program

PubMed Central

Green, Christine Godward; Klein, Elizabeth G.

2011-01-01

Active transportation has been considered as one method to address the American obesity epidemic. To address obesity prevention through built-environment change, the local public health department in Columbus, Ohio, established the Columbus Healthy Places (CHP) program to formally promote active transportation in numerous aspects of community design for the city. In this article, we present a case study of the CHP program and discuss the review of city development rezoning applications as a successful strategy to link public health to urban planning. Prior to the CHP review, 7% of development applications in Columbus included active transportation components; in 2009, 64% of development applications adopted active transportation components specifically recommended by the CHP review. Active transportation recommendations generally included adding bike racks, widening or adding sidewalks, and providing sidewalk connectivity. Recommendations and lessons learned from CHP are provided. PMID:21563711

Laboratory Information Systems in Molecular Diagnostics: Why Molecular Diagnostics Data are Different.

PubMed

Lee, Roy E; Henricks, Walter H; Sirintrapun, Sahussapont J

2016-03-01

Molecular diagnostic testing presents new challenges to information management that are yet to be sufficiently addressed by currently available information systems for the molecular laboratory. These challenges relate to unique aspects of molecular genetic testing: molecular test ordering, informed consent issues, diverse specimen types that encompass the full breadth of specimens handled by traditional anatomic and clinical pathology information systems, data structures and data elements specific to molecular testing, varied testing workflows and protocols, diverse instrument outputs, unique needs and requirements of molecular test reporting, and nuances related to the dissemination of molecular pathology test reports. By satisfactorily addressing these needs in molecular test data management, a laboratory information system designed for the unique needs of molecular diagnostics presents a compelling reason to migrate away from the current paper and spreadsheet information management that many molecular laboratories currently use. This paper reviews the issues and challenges of information management in the molecular diagnostics laboratory.

Cross-Cultural Considerations in U.S. Research Ethics Education

PubMed Central

Heitman, Elizabeth

2014-01-01

Demand among graduate and postdoctoral trainees for international research experience brings together students and investigators from increasingly diverse cultural backgrounds around the world. Educators in research ethics and scientific integrity need to address the cultural aspects of both science and ethics to help all trainees learn ethical practices for effective collaboration with a diverse array of partners. NIH and NSF’s mandates for instruction in the responsible conduct of research do not specifically address the needs of international trainees or U.S. trainees who undertake research projects abroad. Nonetheless, research ethics educators’ typical focus on policy and professional standards can offer trainees and faculty investigators helpful insights into differing ethical values and priorities in research. Examination of linguistic differences can also reveal important conceptual frameworks that shape ethical practice. New resources for teaching research integrity in cross-cultural settings can be a valuable addition to the development of shared understanding of the goals of scientific research. PMID:25574262

Developing a smoking cessation program for Turkish-speaking migrants in Switzerland: novel findings and promising effects.

PubMed

Schnoz, Domenic; Schaub, Michael; Schwappach, David L; Salis Gross, Corina

2011-02-01

Recent studies show that smoking prevalence in the Turkish-speaking migrant population in Switzerland is substantially higher than in the general population. A specific group treatment for Turkish-speaking migrants was developed and tested in order to provide the migrant population with equal access to smoking cessation programs and to improve the migration-sensitive quality of such programs by sociocultural targeting. The evaluation of the program included quantitative (questionnaires t1 and t2 and follow-up by telephone) and qualitative methods (participant observation and semi-structured interviews). The results showed that 37.7% of the 61 participants were smoke free at the 12-month follow-up. The factors of being in a partnership and using nicotine replacement products during the program were positively associated with successful cessation. We also demonstrated the importance of "strong ties" (strong relationships between participants) and the sensitivity of the program to sociocultural (e.g., social aspects of smoking in Turkish culture, which were addressed in relapse prevention), socioeconomic (e.g., low financial resources, which were addressed by providing the course for free), and migration-specific (e.g., underdeveloped access to smoking cessation programs, which was addressed using outreach strategy for recruiting) issues. Overall, the smoking cessation program was successfully tested and is now becoming implemented as a regular service of the Swiss Public Health Program for Tobacco Prevention (by the Swiss Association for Smoking Prevention).

Information Science Panel joint meeting with Imaging Science Panel

NASA Technical Reports Server (NTRS)

1982-01-01

Specific activity in information extraction science (taken to include data handling) is needed to: help identify the bounds of practical missions; identify potential data handling and analysis scenarios; identify the required enabling technology; and identify the requirements for a design data base to be used by the disciplines in determining potential parameters for future missions. It was defined that specific analysis topics were a function of the discipline involved, and therefore no attempt was made to define any specific analysis developments required. Rather, it was recognized that a number of generic data handling requirements exist whose solutions cannot be typically supported by the disciplines. The areas of concern were therefore defined as: data handling aspects of system design considerations; enabling technology for data handling, with specific attention to rectification and registration; and enabling technology for analysis. Within each of these areas, the following topics were addressed: state of the art (current status and contributing factors); critical issues; and recommendations for research and/or development.

Waterpipe tobacco smoking legislation and policy enactment: a global analysis

PubMed Central

Jawad, Mohammed; El Kadi, Lama; Mugharbil, Sanaa; Nakkash, Rima

2015-01-01

Objective (1) To review how current global tobacco control policies address regulation of waterpipe tobacco smoking (WTS). (2) To identify features associated with enactment and enforcement of WTS legislation. Data Sources (1) Legislations compiled by Tobacco Control Laws (www.tobaccocontrollaws.org). (2) Weekly news articles by ‘Google Alerts’ (www.google.com/alerts) from July 2013 to August 2014. Study Selection (1) Countries containing legislative reviews, written by legal experts, were included. Countries prohibiting tobacco sales were excluded. (2) News articles discussing aspects of the WHO FCTC were included. News articles related to electronic-waterpipe, crime, smuggling, opinion pieces or brief mentions of WTS were excluded. Data Abstraction (1) Two reviewers independently abstracted the definition of “tobacco product” and/or “smoking”. Four tobacco control domains (smokefree law, misleading descriptors, health warning labels and advertising/promotion/sponsorship) were assigned one of four categories based on the degree to which WTS had specific legislation. (2) Two investigators independently assigned at least one theme and associated subtheme to each news article. Data Synthesis (1) Reviewed legislations of 62 countries showed that most do not address WTS regulation but instead rely on generic tobacco/smoking definitions to cover all tobacco products. Where WTS was specifically addressed, no additional legislative guidance accounted for the unique way it is smoked, except for in one country specifying health warnings on waterpipe apparatuses (2) News articles mainly reported on noncompliance with public smoking bans, especially in India, Pakistan and the UK. Conclusions A regulatory framework evaluated for effectiveness and tailored for the specificities of WTS needs to be developed. PMID:25550418

Culture-sensitive psychotraumatology.

PubMed

Schnyder, Ulrich; Bryant, Richard A; Ehlers, Anke; Foa, Edna B; Hasan, Aram; Mwiti, Gladys; Kristensen, Christian H; Neuner, Frank; Oe, Misari; Yule, William

2016-01-01

Although there is some evidence of the posttraumatic stress disorder (PTSD) construct's cross cultural validity, trauma-related disorders may vary across cultures, and the same may be true for treatments that address such conditions. Experienced therapists tailor psychotherapy to each patient's particular situation, to the nature of the patient's psychopathology, to the stage of therapy, and so on. In addition, culture-sensitive psychotherapists try to understand how culture enhances the meaning of their patient's life history, the cultural components of their illness and help-seeking behaviors, as well as their expectations with regard to treatment. We cannot take for granted that all treatment-seeking trauma survivors speak our language or share our cultural values. Therefore, we need to increase our cultural competencies. The authors of this article are clinicians and/or researchers from across the globe, working with trauma survivors in various settings. Each author focused on one or more specific cultural aspects of working with trauma survivors and highlighted the following aspects. As a result of culture-specific individual and collective meanings linked to trauma and trauma-related disorders survivors may be exposed to (self-)stigma in the aftermath of trauma. Patients who are reluctant to talk about their traumatic experiences may instead be willing to write or use other ways of accessing the painful memories such as drawing. In other cultures, community and family cohesion are crucial elements of recovery. While awareness of culture-specific aspects is important, we also need to beware of premature cultural stereotyping. When disseminating empirically supported psychotherapies for PTSD across cultures, a number of additional challenges need to be taken into account: many low and middle income countries have very limited resources available and suffer from a poor health infrastructure. In summary, culture-sensitive psychotraumatology means assuming an empathic and non-judgmental attitude, trying to understand each individual's cultural background.

Dimensions of disinhibited personality and their relation with alcohol use and problems

PubMed Central

Gunn, Rachel L.; Finn, Peter R.; Endres, Michael J.; Gerst, Kyle R.; Spinola, Suzanne

2013-01-01

Although alcohol use disorders (AUDs) have been associated with different aspects of disinhibited personality and antisociality, less is known about the specific relationships among different domains of disinhibited personality, antisociality, alcohol use, and alcohol problems. The current study was designed to address three goals, (i) to provide evidence of a three-factor model of disinhibited personality (comprised of impulsivity [IMP], risk taking/ low harm avoidance [RTHA], excitement seeking [ES]), (ii) to test hypotheses regarding the association between each dimension and alcohol use and problems, and (iii) to test the hypothesis that antisociality (social deviance proneness [SDP]) accounts for the direct association between IMP and alcohol problems, while ES is directly related to alcohol use. Measures of disinhibited personality IMP, RTHA, ES and SDP and alcohol use and problems were assessed in a sample of young adults (N=474), which included a high proportion of individuals with AUDs. Confirmatory factor analyses supported a three-factor model of disinhibited personality reflecting IMP, RTHA, and ES. A structural equation model (SEM) showed that IMP was specifically associated with alcohol problems, while ES was specifically associated with alcohol use. In a second SEM, SDP accounted for the majority of the variance in alcohol problems associated with IMP. The results suggest aspects of IMP associated with SDP represent a direct vulnerability to alcohol problems. In addition, the results suggest that ES reflects a specific vulnerability to excessive alcohol use, which is then associated with alcohol problems, while RTHA is not specifically associated with alcohol use or problems when controlling for IMP and ES. PMID:23588138

Early integration of the individual student in academic activities: a novel classroom concept for graduate education in molecular biophysics and structural biology

PubMed Central

2014-01-01

Background A key challenge in interdisciplinary research is choosing the best approach from a large number of techniques derived from different disciplines and their interfaces. Results To address this challenge in the area of Biophysics and Structural Biology, we have designed a graduate level course to teach students insightful use of experimental biophysical approaches in relationship to addressing biological questions related to biomolecular interactions and dynamics. A weekly seminar and data and literature club are used to compliment the training in class. The course contains wet-laboratory experimental demonstration and real-data analysis as well as lectures, grant proposal preparation and assessment, and student presentation components. Active student participation is mandatory in all aspects of the class. Students prepare materials for the class receiving individual and iterative feedback from course directors and local experts generating high quality classroom presentations. Conclusions The ultimate goal of the course is to teach students the skills needed to weigh different experimental approaches against each other in addressing a specific biological question by thinking and executing academic tasks like faculty. PMID:25132964

Early integration of the individual student in academic activities: a novel classroom concept for graduate education in molecular biophysics and structural biology.

PubMed

Leuba, Sanford H; Carney, Sean M; Dahlburg, Elizabeth M; Eells, Rebecca J; Ghodke, Harshad; Yanamala, Naveena; Schauer, Grant; Klein-Seetharaman, Judith

2014-01-01

A key challenge in interdisciplinary research is choosing the best approach from a large number of techniques derived from different disciplines and their interfaces. To address this challenge in the area of Biophysics and Structural Biology, we have designed a graduate level course to teach students insightful use of experimental biophysical approaches in relationship to addressing biological questions related to biomolecular interactions and dynamics. A weekly seminar and data and literature club are used to compliment the training in class. The course contains wet-laboratory experimental demonstration and real-data analysis as well as lectures, grant proposal preparation and assessment, and student presentation components. Active student participation is mandatory in all aspects of the class. Students prepare materials for the class receiving individual and iterative feedback from course directors and local experts generating high quality classroom presentations. The ultimate goal of the course is to teach students the skills needed to weigh different experimental approaches against each other in addressing a specific biological question by thinking and executing academic tasks like faculty.

Investigating burden of informal caregivers in England, Finland and Greece: an analysis with the short form of the Burden Scale for Family Caregivers (BSFC-s).

PubMed

Konerding, Uwe; Bowen, Tom; Forte, Paul; Karampli, Eleftheria; Malmström, Tomi; Pavi, Elpida; Torkki, Paulus; Graessel, Elmar

2018-02-01

The burden of informal caregivers might show itself in different ways in different cultures. Understanding these differences is important for developing culture-specific measures aimed at alleviating caregiver burden. Hitherto, no findings regarding such cultural differences between different European countries were available. In this paper, differences between English, Finnish and Greek informal caregivers of people with dementia are investigated. A secondary analysis was performed with data from 36 English, 42 Finnish and 46 Greek caregivers obtained with the short form of the Burden Scale for Family Caregivers (BSFC-s). The probabilities of endorsing the BSFC-s items were investigated by computing a logit model with items and countries as categorical factors. Statistically significant deviation of data from this model was taken as evidence for country-specific response patterns. The two-factorial logit model explains the responses to the items quite well (McFadden's pseudo-R-square: 0.77). There are, however, also statistically significant deviations (p < 0.05). English caregivers have a stronger tendency to endorse items addressing impairments in individual well-being; Finnish caregivers have a stronger tendency to endorse items addressing the conflict between the demands resulting from care and demands resulting from the remaining social life and Greek caregivers have a stronger tendency to endorse items addressing impairments in physical health. Caregiver burden shows itself differently in English, Finnish and Greek caregivers. Accordingly, measures for alleviating caregiver burden in these three countries should address different aspects of the caregivers' lives.

Best practices recommendations for chiropractic care for infants, children, and adolescents: results of a consensus process.

PubMed

Hawk, Cheryl; Schneider, Michael; Ferrance, Randy J; Hewitt, Elise; Van Loon, Meghan; Tanis, Lora

2009-10-01

There has been much discussion about the role of chiropractic care in the evaluation, management, and treatment of pediatric patients. To date, no specific guidelines have been adopted that address this issue from an evidence based perspective. Previous systematic reviews of the chiropractic literature concluded that there is not yet a substantial body of high quality evidence from which to develop standard clinical guidelines. The purpose of this project was to develop recommendations on "best practices" related primarily to the evaluation and spinal manipulation aspects of pediatric chiropractic care; nonmanipulative therapies were not addressed in detail. Based on both clinical experience and the results of an extensive literature search, a set of seed documents was compiled to inform development of the seed statements. These were circulated electronically to the Delphi panel until consensus was reached, which was considered to be present when there was agreement by at least 80% of the panelists. A multidisciplinary panel of 37 was made up primarily of doctors of chiropractic with a mean of 18 years in practice, many with post-graduate training in pediatrics. The panel represented 5 countries and 17 states; there were members of the American Chiropractic Association, the International Chiropractors Association, and the International Chiropractic Pediatric Association. The panel reached a minimum of 80% consensus on the 51 seed statements after 4 rounds. A broad-based panel of experienced chiropractors was able to reach a high level (80%) of consensus regarding specific aspects of the chiropractic approach to clinical evaluation, management, and manual treatment for pediatric patients, based on both scientific evidence and clinical experience.

What can qualitative research do for randomised controlled trials? A systematic mapping review

PubMed Central

O'Cathain, A; Thomas, K J; Drabble, S J; Rudolph, A; Hewison, J

2013-01-01

Objective To develop an empirically based framework of the aspects of randomised controlled trials addressed by qualitative research. Design Systematic mapping review of qualitative research undertaken with randomised controlled trials and published in peer-reviewed journals. Data sources MEDLINE, PreMEDLINE, EMBASE, the Cochrane Library, Health Technology Assessment, PsycINFO, CINAHL, British Nursing Index, Social Sciences Citation Index and ASSIA. Eligibility criteria Articles reporting qualitative research undertaken with trials published between 2008 and September 2010; health research, reported in English. Results 296 articles met the inclusion criteria. Articles focused on 22 aspects of the trial within five broad categories. Some articles focused on more than one aspect of the trial, totalling 356 examples. The qualitative research focused on the intervention being trialled (71%, 254/356); the design, process and conduct of the trial (15%, 54/356); the outcomes of the trial (1%, 5/356); the measures used in the trial (3%, 10/356); and the target condition for the trial (9%, 33/356). A minority of the qualitative research was undertaken at the pretrial stage (28%, 82/296). The value of the qualitative research to the trial itself was not always made explicit within the articles. The potential value included optimising the intervention and trial conduct, facilitating interpretation of the trial findings, helping trialists to be sensitive to the human beings involved in trials, and saving money by steering researchers towards interventions more likely to be effective in future trials. Conclusions A large amount of qualitative research undertaken with specific trials has been published, addressing a wide range of aspects of trials, with the potential to improve the endeavour of generating evidence of effectiveness of health interventions. Researchers can increase the impact of this work on trials by undertaking more of it at the pretrial stage and being explicit within their articles about the learning for trials and evidence-based practice. PMID:23794542

Evolution and development of the vertebrate ear

NASA Technical Reports Server (NTRS)

Fritzsch, B.; Beisel, K. W.

2001-01-01

This review outlines major aspects of development and evolution of the ear, specifically addressing issues of cell fate commitment and the emerging molecular governance of these decisions. Available data support the notion of homology of subsets of mechanosensors across phyla (proprioreceptive mechanosensory neurons in insects, hair cells in vertebrates). It is argued that this conservation is primarily related to the specific transducing environment needed to achieve mechanosensation. Achieving this requires highly conserved transcription factors that regulate the expression of the relevant structural genes for mechanosensory transduction. While conserved at the level of some cell fate assignment genes (atonal and its mammalian homologue), the ear has also radically reorganized its development by implementing genes used for cell fate assignment in other parts of the developing nervous systems (e.g., neurogenin 1) and by evolving novel sets of genes specifically associated with the novel formation of sensory neurons that contact hair cells (neurotrophins and their receptors). Numerous genes have been identified that regulate morphogenesis, but there is only one common feature that emerges at the moment: the ear appears to have co-opted genes from a large variety of other parts of the developing body (forebrain, limbs, kidneys) and establishes, in combination with existing transcription factors, an environment in which those genes govern novel, ear-related morphogenetic aspects. The ear thus represents a unique mix of highly conserved developmental elements combined with co-opted and newly evolved developmental elements.

Breeding strawberry (Fragaria X ananassa Duch) to increase fruit nutritional quality.

PubMed

Capocasa, F; Diamanti, J; Tulipani, S; Battino, M; Mezzetti, B

2008-01-01

In the last few years the nutritional value of fruit has been widely studied and requested by the consumers, especially for protection against cardiovascular events, cancer and others as well as for the general health benefits it can provide. These benefits can be ascribed mainly to the Total Antioxidant Capacity (TAC) of fruit which is determined by a complex combination of bioactive compounds, generally related to specific characteristics of the genotype and of its interaction with the environment. Strawberry breeding programs are currently used to acquire new varieties improved for specific agronomic (Yield and Size), qualitative (Firmness, Sugars Content and Acidity) and sensorial (Colour and Aroma) characteristics, all combined to increased disease resistance and plant adaptability. Nowadays, besides to all these parameters is necessary to look for the specific bioactive components well known for their effect on human health. This aspect is now highly requested by the consumer. By testing different commercial strawberry varieties, a wide difference among their production and fruit quality, mostly related to their adaptability to the local evaluation conditions, is generally detected. Regarding their nutritional values, only few varieties nowadays differ for their higher phenol content and total antioxidant capacity. By taking into account this knowledge different breeding programs specifically addressed to increase fruit nutritional value, have been started. A first approach is based on the use of inter-specific crosses within wild and cultivated genotypes, so to increase variability for these characters, while the second by considering the intra-specific crosses within cultivars already known for their agronomic behavior and good quality performance. Herewith, we report on the major aspects related to breeding program aimed to increase strawberry fruit nutritional quality and what we can expect for the improvement of consumer acceptability of this fruit.

Transport, energy and environment

DOT National Transportation Integrated Search

1996-12-01

The conference addressed economic and broader policy issues as well as technological perspectives. Further, focus was primarily on medium to long term aspects. The conference was primarily devoted to Euorpean issues, but papers were also addressing g...

Ergonomic aspects simulation digital online: an educational game proposal to promote environmental education.

PubMed

Arbex, D F; Jappur, R; Selig, P; Varvakis, G

2012-01-01

This article addresses the ergonomic criteria that guide the construction of an educational game called Environmental Simulator. The focus is on environment navigation considering aspects of content architecture and its esthetics functionality.

Attenuating mass concrete effects in drilled shafts.

DOT National Transportation Integrated Search

2009-09-01

Drilled shafts are large diameter cast in place concrete foundation elements that until recently were not viewed with the same scrutiny as other massive concrete elements when considering mass concrete aspects. This study addressed three aspects of t...

Cleaner production in a remanufacturing process of air compressors.

PubMed

Esquer, Javier; Arvayo, Jose Angel; Alvarez-Chavez, Clara Rosalia; Munguia-Vega, Nora Elba; Velazquez, Luis

2017-03-01

This article provides relevant results of a cleaner production program conducted in a company dedicated to remanufacturing air compressors in the city of Hermosillo, Sonora, Mexico. The overall study design was based on an integration of acknowledged cleaner production and pollution prevention programs. Although this kind of program also involves environmental issues, this study focused on occupational health and safety by addressing different aspects of the work environment: ergonomic, physical (noise and lighting), and chemical. Particularly, ergonomic aspects were evaluated through the Modular Arrangement of Predetermined Time Standards (MODAPTS) method. For physical aspects, noise and lighting were addressed through Standard No. NOM-011-STPS-2001 and Standard No. NOM-025-STPS-2008 respectively. In addition, chemical aspects were analyzed through material safety data sheets and different search tools. Root causes of each risk were identified, and options to prevent, eliminate, and/or reduce each risk have been provided.

Review of nutrition guidelines relevant for adolescents in low- and middle-income countries.

PubMed

Lassi, Zohra S; Mansoor, Tarab; Salam, Rehana A; Bhutta, Shereen Z; Das, Jai K; Bhutta, Zulfiqar A

2017-04-01

The economic and social well-being of any country will one day depend on its current adolescent population. To provide a good foundation for healthy adolescent development, healthy diet, along with physical activity and adequate nutrients, is necessary. Therefore, addressing the nutrition needs of adolescents could be an important step toward breaking the vicious cycle of intergenerational malnutrition, chronic diseases, and poverty. These problems could be addressed with timely recognition and appropriately delivered interventions. Our aim here is to review the existing guidelines on various aspects of nutrition interventions for adolescents and young women. We review all of the major existing guidelines on adolescent nutrition. We were able to find 18 guideline bodies that covered some form of nutritional advice in guidelines that targeted adolescents. Although the guidelines that focus specifically on this age group are limited in scope, we also extrapolated recommendations from guidelines focused on adults, women of reproductive age, and pregnant women, which were based on evidence that included populations of adolescent girls. We were able to extract and synthesize specific directives for nutrition in adolescents, macro- and micronutrient supplementation, exercise, obesity, and nutrition during preconception, pregnancy, and the postconception period. © 2017 New York Academy of Sciences.

Using PROMs to guide patients and practitioners through the head and neck cancer journey

PubMed Central

Rogers, Simon N; Barber, Brittany

2017-01-01

The measurement of patient-reported outcome measures (PROMs) following head and neck cancer (HNC) has the capacity to substantially enhance the care of patients and their care-givers following the diagnosis and treatment of HNC. Literature concerning PROMs has increased exponentially in the past 2 decades, producing a vast array of data upon which the multidisciplinary team can reflect. For this review, “Handle On QOL” has been used as a source of references to illustrate the points raised. PROMs are contextualized by considering the clinically-distinct key stages that cancer patients endure: diagnosis, treatment, acute toxicity, early recovery, late effects, recurrence, and palliation. The PROMs are considered in six main categories: 1) those addressing cornucopia of issues not specific to cancer; 2) those addressing issues common to all cancers; 3) questionnaires with items specific to HNC; 4) questionnaires that focus on a particular aspect of head and neck function; 5) those measuring psychological concerns, such as depression, anxiety, or self-esteem; and 6) item prompt lists. Potential benefits of PROMs in clinical practice are discussed, as are barriers to use. The way forward in integrating PROMs into routine HNC care is discussed with an emphasis on information technology. PMID:29184455

Children's books and the nature of science: A multisite naturalistic case study of three elementary teachers in the rural southeast

NASA Astrophysics Data System (ADS)

Bricker, Patricia Lynn

This naturalistic case study describes the efforts of three elementary teachers in a rural southeastern school to use children's books in support of inquiry-based science and specifically addresses issues related to the nature of science. Data were collected through 26 classroom and meeting observations, 16 semi-structured and informal interviews, 35 documents and 76 children's books used by the teachers. Three themes were identified related to the nature of science and the selection and use of children's books in the teachers' second, fourth, and fifth grade classrooms. (1) Science was portrayed as a human endeavor that connects to the lives of people and that involves fascination, passion, and interest; imagination and creativity; values; and diverse views. The collection of books was analyzed to look specifically at race, culture, and gender issues. While women, people of color, and different cultures were represented in the book collection, they were not represented well when considering the collection as a whole. (2) Books and the teachers' use of them supported firsthand investigation of the natural world and the idea that empirical evidence underlies scientific understanding. This theme involved observation and journaling, identification of questions to investigate and procedures to use, reasonable interpretations of results, and inferential thinking. (3) Books helped teach about the durable body of scientific knowledge we have discovered over time. They were used to broaden background knowledge and as references after firsthand investigations. The complexity of science education is revealed in these cases. The teachers were able to artfully balance multiple aspects of the nature of science in their book selection and presentation. Particularly promising aspects include their work to use fiction and poetry to promote connections between imagination, creativity and science and their innovative use of books to help students interpret data and infer. Important aspects of the nature of science were not addressed in these themes---including the tentative nature of knowledge, the unknowns we have about the natural world, and an understanding of scientific theories and laws. Issues of race, culture, and gender in the books revealed the crucial need to help teachers embrace critical ways of thinking.

Meditative Movement, Energetic, and Physical Analyses of Three Qigong Exercises: Unification of Eastern and Western Mechanistic Exercise Theory.

PubMed

Klein, Penelope; Picard, George; Baumgarden, Joseph; Schneider, Roger

2017-09-23

Abstract : Qigong is the meditative movement and therapeutic exercise of Eastern medicine. A growing body of evidence is validating its health benefits leading to mechanistic questions of how it works. The purpose of this article is to explore mechanisms of action related to Qigong, with the intent of unifying Eastern and Western exercise theory and to present a model for Qigong exercise analysis. Three exercises from a standardized Qigong form: 'Plucking the Stars', 'Lotus Leaves Rustle in the Wind', and 'Pacing Forwards and Backwards' were selected for meditative, energetic, and physical analyses. Meditative aspects include relaxation response, interoception and exteroception. Energetic aspects include stimulation of meridians through mental intent, acupressure, and self-massage. Physical aspects include flexibility, strength, articular stimulation, neuro-integration, respiratory effect, fascial stretch, visceral massage, balance challenge CranioSacral pump, lymphatic and venous return and glandular stimulation, and physiologic response to relaxation. Knowledge of mechanisms of action for specific Qigong exercises can guide operational definition of Qigong, selection of outcomes assessment in future research, inform prescriptive practice addressing clinical health issues, and advance adoption of Qigong practice within integrative health care. The model of analysis demonstrated in this discussion may assist in these endeavors.

Medical Home Implementation Gaps for Seniors: Perceptions and Experiences of Primary Care Medical Practices.

PubMed

Hoff, Timothy; DePuccio, Matthew

2018-07-01

The study objective was to better understand specific implementation gaps for various aspects of patient-centered medical home (PCMH) care delivered to seniors. The study illuminates the physician and staff experience by focusing on how individuals make sense of and respond behaviorally to aspects of PCMH implementation. Qualitative data from 51 in-depth, semi-structured interviews across six different National Committee for Quality Assurance (NCQA)-accredited primary care practices were collected and analyzed. Physicians and staff identified PCMH implementation gaps for their seniors: (a) performing in-depth clinical assessments, (b) identifying seniors' life needs and linking them with community resources, and (c) care management and coordination, in particular self-management support for seniors. Prior experiences trying to perform these aspects of PCMH care for older adults produced collective understandings that led to inaction and avoidance by medical practices around the first two gaps, and proactive behavior that took strategic advantage of external incentives for addressing the third gap. Greater understanding of physician and staff's PCMH implementation experiences, and the learning that accumulates from these experiences, allows for a deeper understanding of how primary care practices choose to enact the medical home model for seniors on an everyday basis.

Assessment of Emotional Experience and Emotional Recognition in Complicated Grief

PubMed Central

Fernández-Alcántara, Manuel; Cruz-Quintana, Francisco; Pérez-Marfil, M. N.; Catena-Martínez, Andrés; Pérez-García, Miguel; Turnbull, Oliver H.

2016-01-01

There is substantial evidence of bias in the processing of emotion in people with complicated grief (CG). Previous studies have tended to assess the expression of emotion in CG, but other aspects of emotion (mainly emotion recognition, and the subjective aspects of emotion) have not been addressed, despite their importance for practicing clinicians. A quasi-experimental design with two matched groups (Complicated Grief, N = 24 and Non-Complicated Grief, N = 20) was carried out. The Facial Expression of Emotion Test (emotion recognition), a set of pictures from the International Affective Picture System (subjective experience of emotion) and the Symptom Checklist 90 Revised (psychopathology) were employed. The CG group showed lower scores on the dimension of valence for specific conditions on the IAPS, related to the subjective experience of emotion. In addition, they presented higher values of psychopathology. In contrast, statistically significant results were not found for the recognition of emotion. In conclusion, from a neuropsychological point of view, the subjective aspects of emotion and psychopathology seem central in explaining the experience of those with CG. These results are clinically significant for psychotherapists and psychoanalysts working in the field of grief and loss. PMID:26903928

Health aspects of the Tsunami disaster in Asia.

PubMed

Kapila, Mukesh; McGarry, Nichole; Emerson, Elizabeth; Fink, Sheri; Doran, Rodger; Rejto, Khadija; Profili, Maria Cristina

2005-01-01

This is a summary of the proceedings of the Conference on the Health Aspects of the Tsunami Disaster in Asia that was convened by the World Health Organization in Phuket, Thailand from 04-06 May 2005. It contains reviews of the experiences of the health sector and early recovery following the Earthquake and Tsunami with emphasis on what was done well and what could have been done better and the lessons learned that can be incorporated into actions that will mitigate the damage created by future events. It outlines the national and international responses and recovery and the actions taken and not taken by the international community in support of the countries affected. Specific issues addressed include: (1) needs assessments; (2) coordination; (3) filling gaps in essential services, and (4) capacity building at the country level. Each of these aspects is analyzed as to its: (1) appropriateness; (2) adequacy; (3) effectiveness; (4) efficiency; and (5) connectedness. Much of what occurred provided benefits to the stricken population, but there is substantial room for improvement through implementation of the lessons learned. These lessons must be converted into actions in order to mitigate the damage sustained and to enhance our responses to the damage from future events.

Evaluation of Occupational and Environmental Factors in the Assessment of Chronic Cough in Adults: A Systematic Review.

PubMed

Tarlo, Susan M; Altman, Kenneth W; French, Cynthia T; Diekemper, Rebecca L; Irwin, Richard S

2016-01-01

Several recent cough guidelines have advised consideration of occupational or environmental causes for chronic cough, but it is unclear how frequently this recommendation has been routinely applied. Therefore, we undertook a systematic review to address this aspect. Cough guidelines and protocols were reviewed to identify recommendations for assessment of occupational and environmental aspects of chronic cough. The systematic search previously used to identify intervention fidelity to the use of protocols for diagnosis and management of chronic cough in adults was used for this review after extension to June 2015. PubMed, Scopus, and the Cochrane Library were searched using the same search terms and inclusion criteria as previously. Papers that met our criteria were then reviewed to identify methods used to assess occupational and environmental aspects of chronic cough and the outcomes of these assessments. Among the 10 general chronic cough guidelines and protocols identified, only the three published since 2006 included details advising detailed occupational and environmental assessments. One additional cough statement focused entirely on occupational cough. Of the 28 cohort studies of patients with chronic cough that specifically noted that they followed guidelines or protocols, none provided details of occupational and environmental assessments. Despite published recommendations, it is not apparent that occupational and environmental causes for chronic cough are addressed in detail during assessments of patients with chronic cough. This leaves open to speculation whether lack of recognition of an occupational cause may delay important preventive measures, put additional workers at risk, and/or be the reason why a chronic cough may remain unexplained. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Exploring the bases for a mixed reality stroke rehabilitation system, Part II: design of interactive feedback for upper limb rehabilitation.

PubMed

Lehrer, Nicole; Chen, Yinpeng; Duff, Margaret; L Wolf, Steven; Rikakis, Thanassis

2011-09-08

Few existing interactive rehabilitation systems can effectively communicate multiple aspects of movement performance simultaneously, in a manner that appropriately adapts across various training scenarios. In order to address the need for such systems within stroke rehabilitation training, a unified approach for designing interactive systems for upper limb rehabilitation of stroke survivors has been developed and applied for the implementation of an Adaptive Mixed Reality Rehabilitation (AMRR) System. The AMRR system provides computational evaluation and multimedia feedback for the upper limb rehabilitation of stroke survivors. A participant's movements are tracked by motion capture technology and evaluated by computational means. The resulting data are used to generate interactive media-based feedback that communicates to the participant detailed, intuitive evaluations of his performance. This article describes how the AMRR system's interactive feedback is designed to address specific movement challenges faced by stroke survivors. Multimedia examples are provided to illustrate each feedback component. Supportive data are provided for three participants of varying impairment levels to demonstrate the system's ability to train both targeted and integrated aspects of movement. The AMRR system supports training of multiple movement aspects together or in isolation, within adaptable sequences, through cohesive feedback that is based on formalized compositional design principles. From preliminary analysis of the data, we infer that the system's ability to train multiple foci together or in isolation in adaptable sequences, utilizing appropriately designed feedback, can lead to functional improvement. The evaluation and feedback frameworks established within the AMRR system will be applied to the development of a novel home-based system to provide an engaging yet low-cost extension of training for longer periods of time.

Exploring the bases for a mixed reality stroke rehabilitation system, Part II: Design of Interactive Feedback for upper limb rehabilitation

PubMed Central

2011-01-01

Background Few existing interactive rehabilitation systems can effectively communicate multiple aspects of movement performance simultaneously, in a manner that appropriately adapts across various training scenarios. In order to address the need for such systems within stroke rehabilitation training, a unified approach for designing interactive systems for upper limb rehabilitation of stroke survivors has been developed and applied for the implementation of an Adaptive Mixed Reality Rehabilitation (AMRR) System. Results The AMRR system provides computational evaluation and multimedia feedback for the upper limb rehabilitation of stroke survivors. A participant's movements are tracked by motion capture technology and evaluated by computational means. The resulting data are used to generate interactive media-based feedback that communicates to the participant detailed, intuitive evaluations of his performance. This article describes how the AMRR system's interactive feedback is designed to address specific movement challenges faced by stroke survivors. Multimedia examples are provided to illustrate each feedback component. Supportive data are provided for three participants of varying impairment levels to demonstrate the system's ability to train both targeted and integrated aspects of movement. Conclusions The AMRR system supports training of multiple movement aspects together or in isolation, within adaptable sequences, through cohesive feedback that is based on formalized compositional design principles. From preliminary analysis of the data, we infer that the system's ability to train multiple foci together or in isolation in adaptable sequences, utilizing appropriately designed feedback, can lead to functional improvement. The evaluation and feedback frameworks established within the AMRR system will be applied to the development of a novel home-based system to provide an engaging yet low-cost extension of training for longer periods of time. PMID:21899779

Structural Design Exploration of an Electric Powered Multi-Propulsor Wing Configuration

NASA Technical Reports Server (NTRS)

Moore, James B.; Cutright, Steve

2017-01-01

Advancements in aircraft electric propulsion may enable an expanded operational envelope for electrically powered vehicles compared to their internal combustion engine counterparts. High aspect ratio wings provide additional lift and drag reduction for a proposed multi-propulsor design, however, the challenge is to reduce the weight of wing structures while maintaining adequate structural and aeroelastic margins. Design exploration using a conventional design-and-build philosophy coupled with a finite element method (FEM)-based design of experiments (DOE) strategy are presented to examine high aspect ratio wing structures that have spanwise distributed electric motors. Multiple leading-edge-mounted engine masses presented a challenge to design a wing within acceptable limits for dynamic and aeroelastic stability. Because the first four primary bending eigenmodes of the proposed wing structure are very sensitive to outboard motor placement, safety-of-flight requirements drove the need for multiple spars, rib attachments, and outboard structural reinforcements in the design. Global aeroelasticity became an increasingly important design constraint during the on-going design process, with outboard motor pod flutter ultimately becoming a primary design constraint. Designers successively generated models to examine stress, dynamics, and aeroelasticity concurrently. This research specifically addressed satisfying multi-disciplinary design criteria to generate fluid-structure interaction solution sets, and produced high aspect ratio primary structure designs for the NASA Scalable Convergent Electric Propulsion Technology and Operations Research (SCEPTOR) project in the Aeronautic Research Mission Directorate at NASA. In this paper, a dynamics-driven, quasi-inverse design methodology is presented to address aerodynamic performance goals and structural challenges encountered for the SCEPTOR demonstrator vehicle. These results are compared with a traditional computer aided design based approach.

Current Practices in Runway Configuration Management (RCM) and Arrival/Departure Runway Balancing (ADRB)

NASA Technical Reports Server (NTRS)

Lohr, Gary W.; Williams, Daniel M.

2008-01-01

Significant air traffic increases are anticipated for the future of the National Airspace System (NAS). To cope with future traffic increases, fundamental changes are required in many aspects of the air traffic management process including the planning and use of NAS resources. Two critical elements of this process are the selection of airport runway configurations, and the effective management of active runways. Two specific research areas in NASA's Airspace Systems Program (ASP) have been identified to address efficient runway management: Runway Configuration Management (RCM) and Arrival/Departure Runway Balancing (ADRB). This report documents efforts in assessing past as well as current work in these two areas.

Exploring the business case for improving the quality of health care for children.

PubMed

Homer, Charles

2004-01-01

A recent examination of the business case for improving quality in health care found few financial incentives (and sizable barriers) for health care organizations interested in investing in quality improvement. That analysis did not consider the special case of children's health care. To address this gap, an expert panel delineated aspects of children's health care-such as the need for care, patterns of use, and how care is organized and financed-that differ from adult care. It then identified barriers and solutions specific to children's health care, to ensure that children's unique needs are not lost in the debate.

Regulatory T Cell and Forkhead Box Protein 3 as Modulators of Immune Homeostasis

PubMed Central

Pereira, Leonn Mendes Soares; Gomes, Samara Tatielle Monteiro; Ishak, Ricardo; Vallinoto, Antonio Carlos Rosário

2017-01-01

The transcription factor forkhead box protein 3 (FOXP3) is an essential molecular marker of regulatory T cell (Treg) development in different microenvironments. Tregs are cells specialized in the suppression of inadequate immune responses and the maintenance of homeostatic tolerance. Studies have addressed and elucidated the role played by FOXP3 and Treg in countless autoimmune and infectious diseases as well as in more specific cases, such as cancer. Within this context, the present article reviews aspects of the immunoregulatory profile of FOXP3 and Treg in the management of immune homeostasis, including issues relating to pathology as well as immune tolerance. PMID:28603524

Inorganic Photovoltaics Materials and Devices: Past, Present, and Future

NASA Technical Reports Server (NTRS)

Hepp, Aloysius F.; Bailey, Sheila G.; Rafaelle, Ryne P.

2005-01-01

This report describes recent aspects of advanced inorganic materials for photovoltaics or solar cell applications. Specific materials examined will be high-efficiency silicon, gallium arsenide and related materials, and thin-film materials, particularly amorphous silicon and (polycrystalline) copper indium selenide. Some of the advanced concepts discussed include multi-junction III-V (and thin-film) devices, utilization of nanotechnology, specifically quantum dots, low-temperature chemical processing, polymer substrates for lightweight and low-cost solar arrays, concentrator cells, and integrated power devices. While many of these technologies will eventually be used for utility and consumer applications, their genesis can be traced back to challenging problems related to power generation for aerospace and defense. Because this overview of inorganic materials is included in a monogram focused on organic photovoltaics, fundamental issues and metrics common to all solar cell devices (and arrays) will be addressed.

An Integrated Conceptual Framework for the Development of Asian American Children and Youth.

PubMed

Mistry, Jayanthi; Li, Jin; Yoshikawa, Hirokazu; Tseng, Vivian; Tirrell, Jonathan; Kiang, Lisa; Mistry, Rashmita; Wang, Yijie

2016-07-01

The diversity of circumstances and developmental outcomes among Asian American children and youth poses a challenge for scholars interested in Asian American child development. This article addresses the challenge by offering an integrated conceptual framework based on three broad questions: (a) What are theory-predicated specifications of contexts that are pertinent for the development of Asian American children? (b) What are the domains of development and socialization that are particularly relevant? (c) How can culture as meaning-making processes be integrated in conceptualizations of development? The heuristic value of the conceptual model is illustrated by research on Asian American children and youth that examines the interconnected nature of specific features of context, pertinent aspects of development, and interpretive processes. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.

Compression of Martian atmosphere for production of oxygen

NASA Technical Reports Server (NTRS)

Lynch, D. C.; Cutler, A. H.; Nolan, P. E.

1991-01-01

The compression of CO2 from the Martian atmosphere for production of O2 via an electrochemical cell is addressed. Design specifications call for an oxygen production rate of 10 kg per day and for compression of 50 times that mass of CO2. Those specifications require a compression rate of over 770 cfm at standard Martian temperature and pressure (SMTP). Much of the CO2 being compressed represents waste, unless it can be recycled. Recycling can reduce the volume of gas that must be compressed to 40 cfm at SMTP. That volume reduction represents significant mass savings in the compressor, heating equipment, filters, and energy source. Successful recycle of the gas requires separation of CO (produced in the electrochemical cell) from CO2, N2, and Ar found in the Martian atmosphere. That aspect was the focus of this work.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

At the opening of the Symposium, Dr. Sharrah, Senior Vice President of Continental Oil Company, addressed the attendees, and his remarks are included in this volume. The Symposium was concluded by workshops which addressed specific topics. The topical titles are as follows: alcohol uses; production; environment and safety; and socio-economic. The workshops reflected a growing confidence among the attendees that the alcohols from coal, remote natural gas and biomass do offer alternatives to petroleum fuels. Further, they may, in the long run, prove to be equal or superior to the petroleum fuels when the aspects of performance, environment, health andmore » safety are combined with the renewable aspect of the biomass derived alcohols. Although considerable activity in the production and use of alcohols is now appearing in many parts of the world, the absence of strong, broad scale assessment and support for these fuels by the United States Federal Government was a noted point of concern by the attendees. The environmental consequence of using alcohols continues to be more benign in general than the petroleum based fuels. The exception is the family of aldehydes. Although the aldehydes are easily suppressed by catalysts, it is important to understand their production in the combustion process. Progress is being made in this regard. Of course, the goal is to burn the alcohols so cleanly that catalytic equipment can be eliminated. Separate abstracts are prepared for the Energy Data Base for individual presentations.« less

How to Address the Volitional Dimension of the Engineer's Social Responsibility

ERIC Educational Resources Information Center

Heikkero, T.

2008-01-01

In this paper I argue that volitional aspects, i.e. ethos, attitude, pathos, will, underlying emotion, in engineering action need to be addressed when teaching social responsibility within the engineering curriculum. After presenting reasons for this claim, I look at two different, but not mutually exclusive, approaches to address volitional…

Moving toward mainstream: perspectives on enhancing therapy with men.

PubMed

Wade, Jay C; Good, Glenn E

2010-09-01

Psychotherapists began sharing their clinical experiences with men's gender-related psychological issues and the challenges of addressing them in therapy during the late 1970s and early 1980s (e.g., O'Neil, 1981; Scher, 1979; Skovholt, 1978). However, it has taken several decades for these messages and the accompanying research to yield advances that are being adopted into more mainstream psychotherapeutic practices. Over the recent three decades, the theory, research, and clinical wisdom about psychotherapy with men can be viewed as falling into several main clusters. Specifically, there is literature and research providing: - General information on masculine socialization and the psychology of men. - Information about specific issues that men and male clients bring to therapy. - Information about the expectations and experiences of specific groups of men (e.g., men of differing racial/ethnic backgrounds, geographical regions, age cohorts, spiritual/religious beliefs, differing physical ability statuses). - Suggestions for addressing men's reluctance to seek psychotherapy and the challenges associated with forming therapeutic working alliances with men when they do come to therapy. - Suggestions regarding adjustments to psychotherapeutic processes for conducting effective psychotherapy with men. - Development and assessment of instruments to assess endorsement of various male norms and of aspects of men's gender role conflict and stress. Reviewing the earliest writings, some of these pioneering therapists' initial clinical observations remain highly relevant today. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

Biomimetic materials in the utility industry: A program plan for research opportunities, volume 2. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richman, R.H.; McNaughton, W.P.

1996-09-01

This report is the second of a two-volume set addressing the state-of-the-art and outlook for the application of biomimetic materials. The first volume examined achievements in mimicking novel aspects of biological systems in five broad categories: (1) Mimicking of Natural Material Designs, (2) Biomimetic Materials Processing, (3) Artificial Photosynthesis, (4) Biomimetic Molecular Electronics, and (5) Biomimetic Catalysis. Each topic was examined as to current activities and approaches, key aspects, unresolved issues, and implications for the power industry. Key researchers, their organizations, the main thrusts of investigation, achievements, and funding agencies were also summarized. This volume highlights opportunities for future researchmore » activities in biomimetics that could be valuable to the U.S. utility industry. Nineteen specific research projects have been identified. These opportunities are outlined in four classes: (1) technology awareness, (2) modeling and experimental studies, (3) state-of-the-art and outlook studies: developing experimental plans, and (4) concept feasibility studies.« less

Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.

PubMed

Wang, Yuan-Yuan; Lehuédé, Camille; Laurent, Victor; Dirat, Béatrice; Dauvillier, Stéphanie; Bochet, Ludivine; Le Gonidec, Sophie; Escourrou, Ghislaine; Valet, Philippe; Muller, Catherine

2012-11-28

Among the many different cell types surrounding breast cancer cells, the most abundant are those that compose mammary adipose tissue, mainly mature adipocytes and progenitors. New accumulating recent evidences bring the tumor-surrounding adipose tissue into the light as a key component of breast cancer progression. The purpose of this review is to emphasize the role that adipose tissue might play by locally affecting breast cancer cell behavior and subsequent clinical consequences arising from this dialog. Two particular clinical aspects are addressed: obesity that was identified as an independent negative prognostic factor in breast cancer and the oncological safety of autologous fat transfer used in reconstructive surgery for breast cancer patients. This is preceded by the overall description of adipose tissue composition and function with special emphasis on the specificity of adipose depots and the species differences, key experimental aspects that need to be taken in account when cancer is considered. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

On the Origin of Interoception

PubMed Central

Ceunen, Erik; Vlaeyen, Johan W. S.; Van Diest, Ilse

2016-01-01

Over the course of a century, the meaning of interoception has changed from the restrictive to the inclusive. In its inclusive sense, it bears relevance to every individual via its link to emotion, decision making, time-perception, health, pain, and various other areas of life. While the label for the perception of the body state changes over time, the need for an overarching concept remains. Many aspects can make any particular interoceptive sensation unique and distinct from any other interoceptive sensation. This can range from the sense of agency, to the physical cause of a sensation, the ontogenetic origin, the efferent innervation, and afferent pathways of the tissue involved amongst others. In its overarching meaning, interoception primarily is a product of the central nervous system, a construct based on an integration of various sources, not per se including afferent information. This paper proposes a definition of interoception as based on subjective experience, and pleas for the use of specific vocabulary in addressing the many aspects that contribute to it. PMID:27242642

The assessment and treatment of prosodic disorders and neurological theories of prosody.

PubMed

Diehl, Joshua J; Paul, Rhea

2009-08-01

In this article, we comment on specific aspects of Peppé (Peppé, 2009). In particular, we address the assessment and treatment of prosody in clinical settings and discuss current theory on neurological models of prosody. We argue that in order for prosodic assessment instruments and treatment programs to be clinical effective, we need assessment instruments that: (1) have a representative normative comparison sample and strong psychometric properties; (2) are based on empirical information regarding the typical sequence of prosodic acquisition and are sensitive to developmental change; (3) meaningfully subcategorize various aspects of prosody; (4) use tasks that have ecological validity; and (5) have clinical properties, such as length and ease of administration, that allow them to become part of standard language assessment batteries. In addition, we argue that current theories of prosody processing in the brain are moving toward network models that involve multiple brain areas and are crucially dependent on cortical communication. The implications of these observations for future research and clinical practice are outlined.

On the computational aspects of comminution in discrete element method

NASA Astrophysics Data System (ADS)

Chaudry, Mohsin Ali; Wriggers, Peter

2018-04-01

In this paper, computational aspects of crushing/comminution of granular materials are addressed. For crushing, maximum tensile stress-based criterion is used. Crushing model in discrete element method (DEM) is prone to problems of mass conservation and reduction in critical time step. The first problem is addressed by using an iterative scheme which, depending on geometric voids, recovers mass of a particle. In addition, a global-local framework for DEM problem is proposed which tends to alleviate the local unstable motion of particles and increases the computational efficiency.

How do countries regulate the health sector? Evidence from Tanzania and Zimbabwe.

PubMed

Kumaranayake, L; Mujinja, P; Hongoro, C; Mpembeni, R

2000-12-01

The health sectors in many low- and middle-income countries have been characterized in recent years by extensive private sector activity. This has been complemented by increasing public-private linkages, such as the contracting-out of selected services or facilities, development of new purchasing arrangements, franchising and the introduction of vouchers. Increasingly, however, experience with the private sector has indicated a number of problems with the quality, price and distribution of private health services, and thus led to a growing focus on the role of government in regulation. This paper presents the existing network of regulations governing private activity in the health sectors of Tanzania and Zimbabwe, and their appropriateness in the context of emerging market realities. It draws on a comparative mapping exercise reviewing the complexity of the variables currently being regulated, the level of the health system at which they apply, and the specific instruments being used. Findings indicate that much of the existing regulation occurs through legislation. There is still very much a focus on the 'social' rather than 'economic' aspects of regulation within the health sector. Recent changes have attempted to address aspects of private health provision, but some very key gaps remain. In particular, current regulations in Tanzania and Zimbabwe: (1) focus on individual inputs rather than health system organizations; (2) aim to control entry and quality rather than explicitly quantity, price or distribution; and (3) fail to address the market-level problems of anti-competitive practices and lack of patient rights. This highlights the need for additional measures to promote consumer protection and address the development of new private markets such as for health insurance or laboratory and other ancillary services.

Waterpipe tobacco smoking legislation and policy enactment: a global analysis.

PubMed

Jawad, Mohammed; El Kadi, Lama; Mugharbil, Sanaa; Nakkash, Rima

2015-03-01

(1) To review how current global tobacco control policies address regulation of waterpipe tobacco smoking (WTS). (2) To identify features associated with enactment and enforcement of WTS legislation. (1) Legislations compiled by Tobacco Control Laws (www.tobaccocontrollaws.org). (2) Weekly news articles by 'Google Alerts' (www.google.com/alerts) from July 2013 to August 2014. (1) Countries containing legislative reviews, written by legal experts, were included. Countries prohibiting tobacco sales were excluded. (2) News articles discussing aspects of the WHO FCTC were included. News articles related to electronic-waterpipe, crime, smuggling, opinion pieces or brief mentions of WTS were excluded. (1) Two reviewers independently abstracted the definition of "tobacco product" and/or "smoking". Four tobacco control domains (smokefree law, misleading descriptors, health warning labels and advertising/promotion/sponsorship) were assigned one of four categories based on the degree to which WTS had specific legislation. (2) Two investigators independently assigned at least one theme and associated subtheme to each news article. (1) Reviewed legislations of 62 countries showed that most do not address WTS regulation but instead rely on generic tobacco/smoking definitions to cover all tobacco products. Where WTS was specifically addressed, no additional legislative guidance accounted for the unique way it is smoked, except for in one country specifying health warnings on waterpipe apparatuses (2) News articles mainly reported on noncompliance with public smoking bans, especially in India, Pakistan and the UK. A regulatory framework evaluated for effectiveness and tailored for the specificities of WTS needs to be developed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

The Development of a Nystagmus-Specific Quality-of-Life Questionnaire.

PubMed

McLean, Rebecca J; Maconachie, Gail D E; Gottlob, Irene; Maltby, John

2016-09-01

To develop a nystagmus-specific quality-of-life (QOL) questionnaire derived from patient concerns based on eudaimonic aspects of well-being. Cross-sectional study. A total of 206 participants with nystagmus for factor analysis phase and an additional 42 participants with nystagmus for construct validity phase. Questionnaire items were written on the basis of the 6 domains of everyday living affected by nystagmus that were elicited by previous semistructured interviews conducted with 21 people with nystagmus. After consultation with 8 nystagmus experts, 37 items were administered to 206 people with nystagmus. Factor analysis was used to identify latent factors among the items and identify items to propose new nystagmus QOL scales. Cronbach's alpha was used to assess the internal reliability of the new scales. To assess for discriminate and concurrent validity between the new nystagmus scales and an existing vision-related QOL tool, the Visual Function Questionnaire-25 (VFQ-25) was administered to 42 additional participants. Questionnaire response scores on nystagmus-specific QOL items. The factor analysis revealed the retention of 29 items to form a measure comprising 2 distinct subscales reflecting "personal and social" and "physical and environmental" functioning as relating to nystagmus-specific QOL. The Cronbach's alpha coefficients for the "personal and social" functioning scale and "physical and environmental" functioning were 0.95 and 0.93, respectively. Tests for validity of the measure, consistent with a priori predictions, when compared with the VFQ-25, revealed the "physical and environmental" subscale showed concurrent validity (0.88), whereas the "personal and social" subscale was demonstrated to have discriminative validity (0.81). We have developed a 29-item, nystagmus-specific QOL questionnaire (NYS-29) based on eudaimonic aspects of well-being with subscales that address not only physical functioning but also psycho-social issues. The NYS-29 is grounded in the perspectives and concerns of those who have nystagmus and can be used to determine the impact of nystagmus on daily living in terms of both physical and psychosocial aspects. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Which aspects of functioning are relevant for patients with ankylosing spondylitis: results of focus group interviews.

PubMed

Boonen, Annelies; van Berkel, Monique; Cieza, Alarcos; Stucki, Gerold; van der Heijde, Désirée

2009-11-01

To investigate whether concepts important to patients with ankylosing spondylitis (AS) are covered by disease-specific self-report health status instruments. A qualitative focus group study was conducted with AS patients on problems in daily functioning. Group sessions with 4 to 5 patients each were organized up to the point that no new information was brought forward. Group sessions were tape-recorded, transcribed, and divided into meaning units. Concepts contained in the meaning units were extracted. Self-report instruments on health status specific for AS were identified in a literature search. Using the International Classification of Functioning, Disability and Health (ICF) as a common reference, it was determined whether the concepts identified in the focus groups were covered by the instruments. Nineteen patients participated in 4 focus group interviews. In total, 332 unique meaning units were linked to 90 second-level ICF categories, of which 25 referred to body functions, 10 to body structures, 35 to activities and participation and 30 to environmental factors. In addition, several concepts relating to personal factors were identified. Only 47 categories were also covered by one of the self-report instruments in AS. Only a minority of concepts addressed by the AS-specific questionnaires were not revealed as relevant in the interviews. Relevant aspects of the influence of AS are not covered by the classic disease-specific instruments. In particular, the influence of AS on socializing and leisure and the relevance of environmental and personal factors are not adequately assessed by available instruments.

An evaluation framework for funding drugs for rare diseases.

PubMed

Winquist, Eric; Bell, Chaim M; Clarke, Joe T R; Evans, Gerald; Martin, Janet; Sabharwal, Mona; Gadhok, Anita; Stevenson, Helen; Coyle, Doug

2012-01-01

For rare diseases it may be difficult to generate data from randomized trials to support funding of a drug. Enzyme replacement therapies for diseases of inherited metabolic enzyme deficiency provide an example of this dilemma. The Ontario Public Drug Programs convened the Drugs for Rare Diseases Working Group to develop a policy for assessing these drugs. The Drugs for Rare Diseases Working Group developed terms of reference expecting that the ideal policy product would be transparent and consistent and address unique aspects of the treatment of a specific rare condition while being adaptable to other dissimilar conditions. The perspective was that of a public payer addressing requests for funding generated for a specific drug, and included respect for the principles of "accountability for reasonableness" of Daniels and Sabin. A seven-step framework was developed and tested by using the case study of idursulfase for mucopolysaccharidosis II (Hunter disease). Estimation of clinical effectiveness was done by using decision modeling. The model developed informed funding recommendations and ultimately led to an agreement with the manufacturer allowing funding of idursulfase in Ontario. This policy framework attempts to address the policy challenges of funding drugs for rare diseases. The framework will be used to assess other drugs in future and will inevitably require modification with experience. It is hoped that it may be of value to other policymakers. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Institutional analysis of health promotion for older people in Europe - concept and research tool.

PubMed

Sitko, Stojgniew J; Kowalska-Bobko, Iwona; Mokrzycka, Anna; Zabdyr-Jamróz, Michał; Domagała, Alicja; Magnavita, Nicola; Poscia, Andrea; Rogala, Maciej; Szetela, Anna; Golinowska, Stanisława

2016-09-05

European societies are ageing rapidly and thus health promotion for older people (HP4OP) is becoming an increasingly relevant issue. Crucial here is not only the clinical aspect of health promotion but also its organisational and institutional dimension. The latter has been relatively neglected in research on HP4OP. This issue is addressed in this study, constituting a part of the EU project ProHealth65+, engaging ten member countries. This paper is based on two intertwining research goals: (1) exploring which institutions/organisations are performing HP4OP activities in selected European countries (including sectors involved, performed roles of these institutions, organisation of those activities); (2) developing an institutional approach to HP4OP. Thus, the paper provides a description of the analytical tools for further research in this area. The mentioned aims were addressed through the mutual use of two complementary methods: (a) a literature review of scientific and grey literature; and (b) questionnaire survey with selected expert respondents from 10 European countries. The expert respondents, selected by the project's collaborating partners, were asked to fill in a custom designed questionnaire concerning HP4OP institutional aspects. The literature review provided an overview of the organisational arrangements in different HP4OP initiatives. It also enabled the development of functional institutional definitions of health promotion, health promotion activities and interventions, as well as an institutional definition adequate to the health promotion context. The distinctions between sectors were also clarified. The elaborated questionnaires provided in-depth information on countries specifically indicating the key sectors involved in HP4OP in those selected countries. These are: health care, regional/local authorities, NGO's/voluntary institutions. The questionnaire and literature review both resulted in the indication of a significant level of cross-sectorial cooperation in HP4OP. The inclusion of the institutional analysis within the study of HP4OP provides a valuable opportunity to analyse, in a systematic way, good practices in this respect, also in terms of institutional arrangements. A failure to address this aspect in policymaking might potentially cause organisational failure even in evidence-based programmes. This paper frames the perception of this problem.

Crosslinguistic application of English-centric rhythm descriptors in motor speech disorders.

PubMed

Liss, Julie M; Utianski, Rene; Lansford, Kaitlin

2013-01-01

Rhythmic disturbances are a hallmark of motor speech disorders, in which the motor control deficits interfere with the outward flow of speech and by extension speech understanding. As the functions of rhythm are language-specific, breakdowns in rhythm should have language-specific consequences for communication. The goals of this paper are to (i) provide a review of the cognitive-linguistic role of rhythm in speech perception in a general sense and crosslinguistically; (ii) present new results of lexical segmentation challenges posed by different types of dysarthria in American English, and (iii) offer a framework for crosslinguistic considerations for speech rhythm disturbances in the diagnosis and treatment of communication disorders associated with motor speech disorders. This review presents theoretical and empirical reasons for considering speech rhythm as a critical component of communication deficits in motor speech disorders, and addresses the need for crosslinguistic research to explore language-universal versus language-specific aspects of motor speech disorders. Copyright © 2013 S. Karger AG, Basel.

Crosslinguistic Application of English-Centric Rhythm Descriptors in Motor Speech Disorders

PubMed Central

Liss, Julie M.; Utianski, Rene; Lansford, Kaitlin

2014-01-01

Background Rhythmic disturbances are a hallmark of motor speech disorders, in which the motor control deficits interfere with the outward flow of speech and by extension speech understanding. As the functions of rhythm are language-specific, breakdowns in rhythm should have language-specific consequences for communication. Objective The goals of this paper are to (i) provide a review of the cognitive- linguistic role of rhythm in speech perception in a general sense and crosslinguistically; (ii) present new results of lexical segmentation challenges posed by different types of dysarthria in American English, and (iii) offer a framework for crosslinguistic considerations for speech rhythm disturbances in the diagnosis and treatment of communication disorders associated with motor speech disorders. Summary This review presents theoretical and empirical reasons for considering speech rhythm as a critical component of communication deficits in motor speech disorders, and addresses the need for crosslinguistic research to explore language-universal versus language-specific aspects of motor speech disorders. PMID:24157596

Masculinity and HIV: Dimensions of masculine norms that contribute to men’s HIV-related sexual behaviors

PubMed Central

Fleming, Paul J.; DiClemente, Ralph J.; Barrington, Clare

2016-01-01

Numerous studies have documented a relationship between masculine norms and men’s HIV-related sexual behaviors, but intervening upon this relationship requires a nuanced understanding of the specific aspects of masculine norms that shape men’s sexual behaviors. We integrate theories on masculinities with empirical HIV research to identify specific dimensions of masculine norms that influence men’s HIV-related sexual behaviors. We identify three major dimensions of masculine norms that shape men’s sexual behavior: 1) uncontrollable male sex drive, 2) capacity to perform sexually, and 3) power over others. While the existing literature does help explain the relationship between masculine norms and men’s sexual behaviors several gaps remain including: a recognition of context-specific masculinities, an interrogation of the positive influences of masculinity, adoption of an intersectional approach, assessment of changes in norms and behaviors over time, and rigorous evaluations of gender-transformative approaches. Addressing these gaps in future research may optimize prevention efforts. PMID:26696261

Metal colloids and semiconductor quantum dots: Linear and nonlinear optical properties

NASA Technical Reports Server (NTRS)

Henderson, D. O.; My, R.; Tung, Y.; Ueda, A.; Zhu, J.; Collins, W. E.; Hall, Christopher

1995-01-01

One aspect of this project involves a collaborative effort with the Solid State Division of ORNL. The thrust behind this research is to develop ion implantion for synthesizing novel materials (quantum dots wires and wells, and metal colloids) for applications in all optical switching devices, up conversion, and the synthesis of novel refractory materials. In general the host material is typically a glass such as optical grade silica. The ions of interest are Au, Ag, Cd, Se, In, P, Sb, Ga and As. An emphasis is placed on host guest interactions between the matrix and the implanted ion and how the matrix effects and implantation parameters can be used to obtain designer level optical devices tailored for specific applications. The specific materials of interest are: CdSe, CdTe, InAs, GaAs, InP, GaP, InSb, GaSb and InGaAs. A second aspect of this research program involves using porous glass (25-200 A) for fabricating materials of finite size. In this part of the program, we are particularly interested in characterizing the thermodynamic and optical properties of these non-composite materials. We also address how phase diagram of the confined material is altered by the interfacial properties between the confined material and the pore wall.

Performance in sports--With specific emphasis on the effect of intensified training.

PubMed

Bangsbo, J

2015-12-01

Performance in most sports is determined by the athlete's technical, tactical, physiological and psychological/social characteristics. In the present article, the physical aspect will be evaluated with a focus on what limits performance, and how training can be conducted to improve performance. Specifically how intensified training, i.e., increasing the amount of aerobic high-intensity and speed endurance training, affects physiological adaptations and performance of trained subjects. Periods of speed endurance training do improve performance in events lasting 30 s-4 min, and when combined with aerobic high-intensity sessions, also performance during longer events. Athletes in team sports involving intense exercise actions and endurance aspects, such as soccer and basketball, can also benefit from intensified training. Speed endurance training does reduce energy expenditure and increase expression of muscle Na(+), K(+) pump α subunits, which may preserve muscle cell excitability and delay fatigue development during intense exercise. When various types of training are conducted in the same period (concurrent training), as done in a number of sports, one type of training may blunt the effect of other types of training. It is not, however, clear how various training modalities are affecting each other, and this issue should be addressed in future studies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

"Contextualizing Context": Reconciling Environmental Exposures, Social Networks, and Location Preferences in Health Research.

PubMed

Kestens, Yan; Wasfi, Rania; Naud, Alexandre; Chaix, Basile

2017-03-01

The aim of this paper is to review the recent advances in health and place research and discuss concepts useful to explore how context affects health. More specifically, it reviews measures and tools used to account for place; concepts relating to daily mobility and multiple exposure to places, and further points to the intertwining between social and spatial networks to help further our understanding of how context translates into health profiles. Significant advances in environmental or neighborhood effects have been made in the last decades. Specifically, conceptual and methodological developments have improved our consideration of spatial processes, shifting from a residential-based view of context to a more dynamic activity space and daily mobility paradigm. Yet, such advances have led to overlooking other potentially important aspects related to social networks and decision-making processes. With an increasing capacity to collect high-precision data on daily mobility and behavior, new possibilities in understanding how environments relate to behavior and health inequalities arise. Two overlooked aspects need to be addressed: the questions of "with or for whom", and "why". While the former calls for a better consideration of social networks and social interactions, the latter calls for refining our understanding of place preference and decision-making leading to daily mobility and multiple exposures.

Utilising database-driven interactive software to enhance independent home-study in a flipped classroom setting: going beyond visualising engineering concepts to ensuring formative assessment

NASA Astrophysics Data System (ADS)

Comerford, Liam; Mannis, Adam; DeAngelis, Marco; Kougioumtzoglou, Ioannis A.; Beer, Michael

2018-07-01

The concept of formative assessment is considered by many to play an important role in enhancing teaching in higher engineering education. In this paper, the concept of the flipped classroom as part of a blended learning curriculum is highlighted as an ideal medium through which formative assessment practices arise. Whilst the advantages of greater interaction between students and lecturers in classes are numerous, there are often clear disadvantages associated with the independent home-study component that complements timetabled sessions in a flipped classroom setting, specifically, the popular method of replacing traditional classroom teaching with video lectures. This leads to a clear lack of assurances that the cited benefits of a flipped classroom approach are echoed in the home-study arena. Over the past three years, the authors have sought to address identified deficiencies in this area of blended learning through the development of database-driven e-learning software with the capability of introducing formative assessment practices to independent home-study. This paper maps out aspects of two specific evolving practices at separate institutions, from which guiding principles of incorporating formative assessment aspects into e-learning software are identified and highlighted in the context of independent home-study as part of a flipped classroom approach.

Ethical, legal, and social aspects of farm animal cloning in the 6th Framework Programme for Research.

PubMed

Claxton, John; Sachez, Elena; Matthiessen-Guyader, Line

2004-01-01

Cloned livestock have potential importance in the provision of improved medicine as well as in the development of livestock production. The public is, however, increasingly concerned about the social and ethical consequences of these advances in knowledge and techniques. There is unevenness throughout Europe in different Member States' attitudes to research into livestock cloning. Although there is EU legislation controlling the use of animals for research purposes, there is no legislation specifically governing cloning in livestock production. The main EU reference is the 9th Opinion of the European Group on Ethics, which states "Cloning of farm animals may prove to be of medical and agricultural as well as economic benefit. It is acceptable only when the aims and methods are ethically justified and when carried out under ethical conditions." The ethical justification includes the avoidance of suffering, the use of the 3Rs principle and a lack of better alternatives. The Commission addresses these issues in the 6th Framework Programme by promoting the integration of ethical, legal and social aspects in all proposals where they are relevant, by fostering ethical awareness and foresight in the proposals, by encouraging public dialogue, and by supporting specific actions to promote the debate. Research must respect fundamental ethical principles, including animal welfare requirements.

Geostationary platform systems concepts definition study. Volume 2A: Appendixes, book 1

NASA Technical Reports Server (NTRS)

1980-01-01

Appendixes addressing various aspects of a geostationary platform concepts definition study are given. Communication platform traffic requirements, video conferencing forecast, intersatellite link capacity requirements, link budgets, payload data, payload assignments, and platform synthesis are addressed.

Instructional Aspects of Intelligent Tutoring Systems.

ERIC Educational Resources Information Center

Pieters, Jules M., Ed.

This collection contains three papers addressing the instructional aspects of intelligent tutoring systems (ITS): (1) "Some Experiences with Two Intelligent Tutoring Systems for Teaching Computer Programming: Proust and the LISP-Tutor" (van den Berg, Merrienboer, and Maaswinkel); (2) "Some Issues on the Construction of Cooperative…

The Twenty-First LACUS Forum, 1994.

ERIC Educational Resources Information Center

Powell, Mava Jo, Ed.

Fifty-three papers on linguistic theory and language research, including a number of prize-winning essays, address these topics: aspects of discourse analysis; bilingualism; Chinese modal verbs; early bilingual speech; linguistic metatheory; music and accent discrepancy; diphthongs; hiatus; vowel patterns; suprasegmentals; neologisms; aspects of…

[Pain medicine from intercultural and gender-related perspectives].

PubMed

Schiltenwolf, M; Pogatzki-Zahn, E M

2015-10-01

Cultural setting and sex and gender of the patient are important factors affecting the occurrence, severity, clinical course and prognosis of pain and pain-related diseases. Intercultural differences in the perception and verbal expression of symptoms and emotional function are fundamental and it is important to realize these differences in order to understand patients with a migration background. A trusting doctor-patient relationship is generally very sensitive and it is even more difficult to establish when differences in the cultural background impair mutual understanding. Regarding sex and gender there is evidence that females are more susceptible to developing chronic pain conditions, experience more severe pain and respond differently to pain therapy; however, results of recent studies indicate that females are not that different to males when comparing several modalities of experimental pain (although some differences exist). Similarly, sex and gender differences in postoperative pain seem to exist but the differences are relatively small when pain scores are compared. Other aspects, such as the response to analgesics and role of psychosocial factors should be addressed when sex and gender aspects are studied. Similarly, sex and gender differences in the prevalence of chronic pain exist but the results of some studies, e.g. those controlling for confounders, are not very clear. Research is needed to delineate the role of specific aspects affecting sex and gender differences and the underlying mechanisms (e.g. reduced inhibitory control, hormones, psychological aspects and social factors). Altogether, we need to open our minds to some intercultural and sex and gender aspects in the clinical setting. For sex and gender differences we may need a more biopsychosocial approach to understand the underlying differences and differentiate between sex and gender and sex and gender-associated aspects for acute and chronic pain.

Training the Motor Aspects of Pre-driving Skills of Young Adults With and Without Autism Spectrum Disorder.

PubMed

Brooks, Johnell; Kellett, Julie; Seeanner, Julia; Jenkins, Casey; Buchanan, Caroline; Kinsman, Anne; Kelly, Desmond; Pierce, Susan

2016-07-01

The purpose of this study was to investigate the utility of using a driving simulator to address the motor aspects of pre-driving skills with young adults with Autism Spectrum Disorder (ASD). A group of neurotypical control participants and ten participants with ASD completed 18 interactive steering and pedal exercises with the goal to achieve error-free performance. Most participants were able to achieve this goal within five trials for all exercises except for the two most difficult ones. Minimal performance differences were observed between the two groups. Participants with ASD needed more time to complete the tasks. Overall, the interactive exercises and the process used worked well to address motor related aspects of pre-driving skills in young adults with ASD.

Are vision-specific quality of life questionnaires important in assessing rehabilitation for patients with hemianopia post stroke?

PubMed

George, Stacey; Hayes, Allison; Chen, Celia; Crotty, Maria

2011-01-01

To explore the relationship between disability and functional measures with vision-specific quality of life (QoL) measures for people with hemianopia and stroke. The Behavioral Inattention Test (BIT) and the Mayo-Portland Adaptability Inventory (MPAI) were compared with scores on 2 vision-specific QoL measures, the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and Veteran Low Vision Visual Function Questionnaire (VA LV VFQ-48). Rehabilitation hospitals in Adelaide, South Australia. Stroke patients (n = 24) with homonymous hemianopia. Most of the BIT and MPAI scores were significantly associated with the NEI VFQ-25 and VA LV VFQ-48 scores. Behavioral test scores of the BIT and the MPAI total score correlated with more aspects of the QoL measures than the other components of the BIT and the MPAI. BIT and MPAI measure constructs associated with QoL for people with hemianopia following stroke. Vision-specific QoL questionnaires can complement the functional instruments by identifying the domains of difficulty, based on the instrument's subscale, that can guide rehabilitation therapists to address the person's deficit.

Field Trips and the Law.

ERIC Educational Resources Information Center

Troy, Thomas D.; Schwaab, Karl E.

1981-01-01

Legal aspects of field trips are addressed, with special attention on planning and implementation aspects which warrant legal consideration. Suggestions are based on information obtained from studies which reviewed and analyzed court cases, with recommendations geared to lessen the likelihood that negligence suits will result if students sustain…

Final report to the Florida Department of Transportation Systems Planning Office on project "Improvements and enhancements to LOSPLAN 2007".

DOT National Transportation Integrated Search

2011-03-01

This project addressed several aspects of the LOSPLAN software, primarily with respect to incorporating : new FDOT and NCHRP research project results. In addition, some existing computational methodology : aspects were refined to provide more accurat...

High-Throughput Screening in ToxCast/Tox21 (FutureToxII)

EPA Science Inventory

Addressing safety aspects of drugs and environmental chemicals relies extensively on animal testing. However, the quantity of chemicals needing assessment and challenges of species extrapolation require development of alternative approaches. The EPA’s ToxCast program addresses th...

Enabling fast charging – Battery thermal considerations

DOE PAGES

Keyser, Matthew; Pesaran, Ahmad; Li, Qibo; ...

2017-10-23

Battery thermal barriers are reviewed with regards to extreme fast charging. Present-day thermal management systems for battery electric vehicles are inadequate in limiting the maximum temperature rise of the battery during extreme fast charging. If the battery thermal management system is not designed correctly, the temperature of the cells could reach abuse temperatures and potentially send the cells into thermal runaway. Furthermore, the cell and battery interconnect design needs to be improved to meet the lifetime expectations of the consumer. Each of these aspects is explored and addressed as well as outlining where the heat is generated in a cell,more » the efficiencies of power and energy cells, and what type of battery thermal management solutions are available in today’s market. Here, thermal management is not a limiting condition with regard to extreme fast charging, but many factors need to be addressed especially for future high specific energy density cells to meet U.S. Department of Energy cost and volume goals.« less

Psychological perspectives on fear of childbirth.

PubMed

Rondung, Elisabet; Thomtén, Johanna; Sundin, Örjan

2016-12-01

The objective of this narrative review was to examine the literature on fear of childbirth from a psychological perspective, addressing the specificity of childbirth fear, the pathways of fear acquisition, and the physiological, cognitive and behavioral aspects of fear. Systematic procedures for literature search, inclusion and exclusion left 86 original research papers for analysis. Findings summarize the body of knowledge for each area of interest, as well as the number of studies addressing each theme. Overall, few studies adopt a clear-cut psychological perspective, leaving the psychological mechanisms of childbirth fear largely unexplored. Although methodological limitations make conclusions difficult, results give a hint of etiological diversity and possible psychological mechanisms commonly described as transdiagnostic features in anxiety. Systematic investigations of psychological mechanisms, longitudinal studies exploring possible vicious circles of fear, and studies comparing psychological characteristics within the group of women fearing childbirth are identified as research areas of high priority. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

The odd couple: using biomedical and intersectional approaches to address health inequities

PubMed Central

Hankivsky, Olena; Doyal, Lesley; Einstein, Gillian; Kelly, Ursula; Shim, Janet; Weber, Lynn; Repta, Robin

2017-01-01

ABSTRACT Background: Better understanding and addressing health inequities is a growing global priority. Objective: In this paper, we contribute to the literature examining complex relationships between biological and social dimensions in the field of health inequalities. Specifically, we explore the potential of intersectionality to advance current approaches to socio-biological entwinements. Design: We provide a brief overview of current approaches to combining both biological and social factors in a single study, and then investigate the contributions of an intersectional framework to such work. Results: We offer a number of concrete examples of how intersectionality has been used empirically to bring both biological and social factors together in the areas of HIV, post-traumatic stress disorder, female genital circumcision/mutilation/cutting, and cardiovascular disease. Conclusion: We argue that an intersectional approach can further research that integrates biological and social aspects of human lives and human health and ultimately generate better and more precise evidence for effective policies and practices aimed at tackling health inequities. PMID:28641056

The odd couple: using biomedical and intersectional approaches to address health inequities.

PubMed

Hankivsky, Olena; Doyal, Lesley; Einstein, Gillian; Kelly, Ursula; Shim, Janet; Weber, Lynn; Repta, Robin

Better understanding and addressing health inequities is a growing global priority. In this paper, we contribute to the literature examining complex relationships between biological and social dimensions in the field of health inequalities. Specifically, we explore the potential of intersectionality to advance current approaches to socio-biological entwinements. We provide a brief overview of current approaches to combining both biological and social factors in a single study, and then investigate the contributions of an intersectional framework to such work. We offer a number of concrete examples of how intersectionality has been used empirically to bring both biological and social factors together in the areas of HIV, post-traumatic stress disorder, female genital circumcision/mutilation/cutting, and cardiovascular disease. We argue that an intersectional approach can further research that integrates biological and social aspects of human lives and human health and ultimately generate better and more precise evidence for effective policies and practices aimed at tackling health inequities.

Building the U.S. First Offshore Wind Farm-Applying EBM Approaches to Successfully Address Offshore Energy, Commercial Fisheries, and Recreational Boating interactions

NASA Astrophysics Data System (ADS)

Lipsky, A.

2016-12-01

In August 2015 construction commenced on the Block Island Wind Farm, the first offshore wind energy project in the U.S. This pilot-scale offshore energy project, located 18 miles offshore of the Rhode Island mainland, was sited through a comprehensive ocean planning process. As the project progressed into design and construction, our team utilized potent ecosystem based management approaches to great advantage to address the human and resource interactions that existed in the project area. These practices have included designing and executing collaborative long-term monitoring ventures to fill key science gaps and reconcile fisheries concerns, establishing effective industry to industry engagement, and developing durable multi-sector agreements. This presentation will describe the specific EBM approaches used after the planning process was completed to bring the project to construction; highlighting where key aspects of the National Ocean Policy goals and principles have been successfully applied.

Building the U.S. First Offshore Wind Farm-Applying EBM Approaches to Successfully Address Offshore Energy, Commercial Fisheries, and Recreational Boating interactions

NASA Astrophysics Data System (ADS)

Lipsky, A.

2016-02-01

In August 2015 construction commenced on the Block Island Wind Farm, the first offshore wind energy project in the U.S. This pilot-scale offshore energy project, located 18 miles offshore of the Rhode Island mainland, was sited through a comprehensive ocean planning process. As the project progressed into design and construction, our team utilized potent ecosystem based management approaches to great advantage to address the human and resource interactions that existed in the project area. These practices have included designing and executing collaborative long-term monitoring ventures to fill key science gaps and reconcile fisheries concerns, establishing effective industry to industry engagement, and developing durable multi-sector agreements. This presentation will describe the specific EBM approaches used after the planning process was completed to bring the project to construction; highlighting where key aspects of the National Ocean Policy goals and principles have been successfully applied.

Enabling fast charging – Battery thermal considerations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keyser, Matthew; Pesaran, Ahmad; Li, Qibo

Battery thermal barriers are reviewed with regards to extreme fast charging. Present-day thermal management systems for battery electric vehicles are inadequate in limiting the maximum temperature rise of the battery during extreme fast charging. If the battery thermal management system is not designed correctly, the temperature of the cells could reach abuse temperatures and potentially send the cells into thermal runaway. Furthermore, the cell and battery interconnect design needs to be improved to meet the lifetime expectations of the consumer. Each of these aspects is explored and addressed as well as outlining where the heat is generated in a cell,more » the efficiencies of power and energy cells, and what type of battery thermal management solutions are available in today’s market. Here, thermal management is not a limiting condition with regard to extreme fast charging, but many factors need to be addressed especially for future high specific energy density cells to meet U.S. Department of Energy cost and volume goals.« less

What is in our environment that effects puberty?

PubMed

Fisher, Marisa M; Eugster, Erica A

2014-04-01

Recent studies indicate that the onset of puberty is occurring at increasingly younger ages. Many etiologies have been hypothesized to be involved, but environmental exposures are among the most worrisome. Multiple organizations have endorsed the need to study and provide clinical awareness regarding the effect of a child's environment on pubertal timing. This review article summarizes the current understanding of the major environmental influences on pubertal timing, focusing on factors for which the most scientific evidence exists. The research reviewed addresses intrinsic factors unique to each individual, naturally occurring endocrine disruptors and chemical endocrine disruptors. In each category, evidence was found for and against the involvement of specific environmental factors on pubertal timing. Ultimately, an individual's environment is likely comprised of many aspects that collectively contribute to the timing of puberty. The need for research aimed at elucidating the effects of numerous specific yet disparate forms of exposures is emphasized. Copyright © 2013 Elsevier Inc. All rights reserved.

Rotorcraft air transportation

NASA Technical Reports Server (NTRS)

Gilbert, G. A.

1983-01-01

Intermodal relationships and the particular ways in which they affect public transportation applications of rotorcraft are addressed. Some aspects of integrated services and general comparisons with other transportation modes are reviewed. Two potential application scenarios are discussed: down-to-downtown rotorcraft service and urban public transport rotorcraft service. It is concluded that to integrate well with ground access modes community rotorcraft service should be limited stop service with published schedules, and operate on a few specific routes between a few specific destinations. For downtown-to-downtown service, time savings favorable to rotorcraft are benefits that reflect its more direct access, relatively higher line-haul travel speeds, and less circuitous travel. For the scenario of public transport within urban areas, first, improving cruise speeds has a limited potential due to allowing for a ""station spacing'' effect. Secondly, public acceptance of higher acceleration/deceleration rates may be just as effective as a technological innovation as achieving higher cruise speeds.

Job satisfaction and patient care practices of hemodialysis nurses and technicians.

PubMed

Perumal, Seena; Sehgal, Ashwini R

2003-10-01

The quality of hemodialysis care has been the focus of intense scrutiny, yet little is known about the job satisfaction of the nurses and technicians providing this care. We identified 240 nurses and technicians from 307 randomly selected American facilities and asked them about (a) specific domains of job satisfaction, (b) overall job satisfaction, and (c) self-reported patient care practices. Fewer than half of nurses and technicians were satisfied with their pay or their opportunities for advancement. Almost all subjects were satisfied with their personal delivery of patient care, their chance to do things for others, and their job security. About three-fourths of nurses and technicians expressed overall satisfaction with their jobs. Higher job satisfaction was associated with increased attention to patient psychosocial and educational needs. We urge local and national associations of nurses and technicians to collaborate with dialysis facilities, chains, and regulatory agencies to address specific aspects of job satisfaction.

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

NASA Astrophysics Data System (ADS)

Samuelsen, Simone V.; Solov'Yov, Ilia A.; Balboni, Imelda M.; Mellins, Elizabeth; Nielsen, Christoffer Tandrup; Heegaard, Niels H. H.; Astakhova, Kira

2016-10-01

New techniques to detect and quantify antibodies to nucleic acids would provide a significant advance over current methods, which often lack specificity. We investigate the potential of novel antigens containing locked nucleic acids (LNAs) as targets for antibodies. Particularly, employing molecular dynamics we predict optimal nucleotide composition for targeting DNA-binding antibodies. As a proof of concept, we address a problem of detecting anti-DNA antibodies that are characteristic of systemic lupus erythematosus, a chronic autoimmune disease with multiple manifestations. We test the best oligonucleotide binders in surface plasmon resonance studies to analyze binding and kinetic aspects of interactions between antigens and target DNA. These DNA and LNA/DNA sequences showed improved binding in enzyme-linked immunosorbent assay using human samples of pediatric lupus patients. Our results suggest that the novel method is a promising tool to create antigens for research and point-of-care monitoring of anti-DNA antibodies.

Patient communication in hormone therapy.

PubMed

Schnare, S M

2001-01-01

Common regimens of HRT therapy are reviewed, including common routes of hormone administration. Inconsistent patterns of HRT use are discussed, including the reasons women most often give for discontinuing hormone therapies. Specific issues related to misperceptions and fears regarding HRT are clarified, and specific, focused patient education formats are discussed to address women's common concerns about HRT. Obstacles to HRT use are elucidated, with suggestions for clinicians about how to communicate more effectively with women: clinicians must focus on emotional and physical aspects of HRT choices and tailor therapies to the individual patient. Discussing frankly the very serious concerns of women regarding the association between lobular breast cancer and endometrial cancer is important; discussing and preparing women for possible side effects helps patients cope better if and when side effects occur. Finally, offering a wide variety of HRT therapies provides women with a broader choice if an initial regimen is unsuccessful.

Use of convalescent plasma in Ebola virus infection.

PubMed

Garraud, Olivier

2017-02-01

The recent Ebola virus epidemics which threatened three West African countries (Dec.2014-Apr.2016) has urged global collaborative health organizations and countries to set up measures to stop the infection and to treat patients, near half of them being at risk of death. Convalescent plasma-recovered from rescued West Africans-was considered a feasible therapeutic option. Efficacy was difficult to evaluate because of numerous unknowns (especially evolution of neutralizing antibodies), prior to the cessation of active transmission. This raises a large body of questions spanning epidemiological, virological, immunological but also ethical, sociological and anthropological aspects, alongside with public health concerns, in order to be better prepared to the next outbreak. This essay summarizes efforts made by a large number of groups worldwide, and attempts to address still unanswered questions on the benefit of specific versus non-specific plasma on altered-leaking-vascular endothelia in Ebola infection. Copyright © 2016 Elsevier Ltd. All rights reserved.

Concept document of the repository-based software engineering program: A constructive appraisal

NASA Technical Reports Server (NTRS)

1992-01-01

A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

Students' trust judgements in online health information seeking.

PubMed

Rowley, Jennifer; Johnson, Frances; Sbaffi, Laura

2015-12-01

As one of the most active groups of Internet users, students and other young people are active users of digital health information. Yet, research into young people's evaluation of health information is limited, and no previous studies have focused on trust formation. In addition, prior studies on adults' use of digital information do not reach a consensus regarding the key factors in trust formation. This study seeks to address this gap. A questionnaire-based survey was used to collect data from undergraduate students studying a variety of disciplines in one UK university. The Trust in Online Health Information Scale is proposed, and it includes the following dimensions: authority, style, content, usefulness, brand, ease of use, recommendation, credibility, and verification. In addition, inspection of responses to specific items/questions provides further insights into aspects of the information that were of specific importance in influencing trust judgements. © The Author(s) 2014.

Health Disparities in Women

PubMed Central

Hornbuckle, Lyndsey M; Amutah-Onukagha, Ndidiamaka; Bryan, Alicia; Skidmore Edwards, Elizabeth; Madzima, Takudzwa; Massey, Kelly; May, Linda; Robinson, Leah E

2017-01-01

AIMS AND SCOPE Clinical Medicine Insights: Women’s Health is an international, open-access, peer-reviewed journal which considers manuscripts on all aspects of the diagnosis, management, and prevention of disorders specific to women, in addition to related genetic, pathophysiological, and epidemiological topics. Clinical Medicine Insights: Women’s Health aims to provide researchers working in this complex, quickly developing field with online, open access to highly relevant scholarly articles by leading international researchers. In a field where the literature is ever-expanding, researchers increasingly need access to up-to-date, high-quality scholarly articles on areas of specific contemporary interest. This supplement is on Health Disparities in Women. This supplement aims to address this by presenting high-quality articles that allow readers to distinguish the signal from the noise. The editor in chief hopes that through this effort, practitioners and researchers will be aided in finding answers to some of the most complex and pressing issues of our time. PMID:28579867

MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) of skin: Aspects of sample preparation.

PubMed

de Macedo, Cristiana Santos; Anderson, David M; Schey, Kevin L

2017-11-01

MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) allows molecular analysis of biological materials making possible the identification and localization of molecules in tissues, and has been applied to address many questions on skin pathophysiology, as well as on studies about drug absorption and metabolism. Sample preparation for MALDI IMS is the most important part of the workflow, comprising specimen collection and preservation, tissue embedding, cryosectioning, washing, and matrix application. These steps must be carefully optimized for specific analytes of interest (lipids, proteins, drugs, etc.), representing a challenge for skin analysis. In this review, critical parameters for MALDI IMS sample preparation of skin samples will be described. In addition, specific applications of MALDI IMS of skin samples will be presented including wound healing, neoplasia, and infection. Copyright © 2017 Elsevier B.V. All rights reserved.

A Proposal for a Thesaurus for Web Services in Solar Radiation

NASA Technical Reports Server (NTRS)

Gschwind, Benoit; Menard, Lionel; Ranchin, Thierry; Wald, Lucien; Stackhouse, Paul W., Jr.

2007-01-01

Metadata are necessary to discover, describe and exchange any type of information, resource and service at a large scale. A significant amount of effort has been made in the field of geography and environment to establish standards. Efforts still remain to address more specific domains such as renewable energies. This communication focuses on solar energy and more specifically on aspects in solar radiation that relate to geography and meteorology. A thesaurus in solar radiation is proposed for the keys elements in solar radiation namely time, space and radiation types. The importance of time-series in solar radiation is outlined and attributes of the key elements are discussed. An XML schema for encoding metadata is proposed. The exploitation of such a schema in web services is discussed. This proposal is a first attempt at establishing a thesaurus for describing data and applications in solar radiation.

Addressing Personal Issues in Supervision: Impact of Counselors' Experience Level on Various Aspects of the Supervisory Relationship.

ERIC Educational Resources Information Center

Sumerel, Marie B.; Borders, L. Dianne

1996-01-01

In this study, entry-level and advanced counselors (N=40) rated videotaped supervision sessions in which either the counselor's personal issues or skills deficits were addressed. The study's goal was to determine the impact that addressing counselors' personal issues in supervision has on relationship, quality of the session, postsession mood, and…

Psychology in India

ERIC Educational Resources Information Center

Sushma, B.; Padmaja, G.

2011-01-01

Psychology forms the basis of every human activity. The scope of psychology is increasingly widening in various economic, political, social, cultural and technological aspects. Though the application of psychology is extending to various aspects of life, it needs to be indigenised to address the dynamic needs in the various socio-economic contexts…

Mandarin Visual Speech Information

ERIC Educational Resources Information Center

Chen, Trevor H.

2010-01-01

While the auditory-only aspects of Mandarin speech are heavily-researched and well-known in the field, this dissertation addresses its lesser-known aspects: The visual and audio-visual perception of Mandarin segmental information and lexical-tone information. Chapter II of this dissertation focuses on the audiovisual perception of Mandarin…

Addressing Measurement Issues Related to Bullying Involvement

ERIC Educational Resources Information Center

Casper, Deborah M.; Meter, Diana J.; Card, Noel A.

2015-01-01

In this article, we address measurement issues related to select aspects of bullying involvement with the goal of moving psychometrically sound measurement practices toward applied bullying research. We first provide a nontechnical introduction to psychometric considerations in measuring bullying involvement, highlighting the importance of…

From Genetics to Genomics: A Short Introduction for Pediatric Neurologists.

PubMed

Neubauer, Bernd A; Lemke, Johannes R

2016-01-01

It is estimated that in humans approximately 50% of all 22500 genes are needed for the development and maintenance of the nervous system. The introduction of high-throughput technology in genetic analysis has therefore major implications, not only for the investigation of specific disease entities but also for the diagnostic workup of single individuals with neurologic disorders of genetic origin. A short primer for clinicians is presented, addressing aspects of current developments in medical genomics. Significant findings of the last years are exemplified in an educational manner to provide a basic understanding of disease mechanisms that were unraveled by recent genomic analysis. Georg Thieme Verlag KG Stuttgart · New York.

The New HIT: Human Health Information Technology.

PubMed

Leung, Tiffany I; Goldstein, Mary K; Musen, Mark A; Cronkite, Ruth; Chen, Jonathan H; Gottlieb, Assaf; Leitersdorf, Eran

2017-01-01

Humanism in medicine is defined as health care providers' attitudes and actions that demonstrate respect for patients' values and concerns in relation to their social, psychological and spiritual life domains. Specifically, humanistic clinical medicine involves showing respect for the patient, building a personal connection, and eliciting and addressing a patient's emotional response to illness. Health information technology (IT) often interferes with humanistic clinical practice, potentially disabling these core aspects of the therapeutic patient-physician relationship. Health IT has evolved rapidly in recent years - and the imperative to maintain humanism in practice has never been greater. In this vision paper, we aim to discuss why preserving humanism is imperative in the design and implementation of health IT systems.

Experience in Evaluating AAL Solutions in Living Labs

PubMed Central

Colomer, Juan Bautista Montalvá; Salvi, Dario; Cabrera-Umpierrez, Maria Fernanda; Arredondo, Maria Teresa; Abril, Patricia; Jimenez-Mixco, Viveca; García-Betances, Rebeca; Fioravanti, Alessio; Pastorino, Matteo; Cancela, Jorge; Medrano, Alejandro

2014-01-01

Ambient assisted living (AAL) is a complex field, where different technologies are integrated to offer solutions for the benefit of different stakeholders. Several evaluation techniques are commonly applied that tackle specific aspects of AAL; however, holistic evaluation approaches are lacking when addressing the needs of both developers and end-users. Living labs have been often used as real-life test and experimentation environments for co-designing AAL technologies and validating them with relevant stakeholders. During the last five years, we have been evaluating AAL systems and services in the framework of various research projects. This paper presents the lessons learned in this experience and proposes a set of harmonized guidelines to conduct evaluations in living labs. PMID:24763209

Multijunction cells for concentrators: Technology prospects

NASA Technical Reports Server (NTRS)

Ferber, R. R. (Compiler); Costogue, E. N. (Compiler); Shimada, K. (Compiler)

1984-01-01

Development of high-efficiency multijunction solar cells for concentrator applications is a key step in achieving the goals of the U.S. Department of Energy National Photovoltaics Program. This report summarizes findings of an issue study conducted by the Jet Propulsion Laboratory Photovoltaic Analysis and Integration Center, with the assistance of the Solar Energy Research Institute and Sandia National laboratoies, which surveyed multijunction cell research for concentrators undertaken by federal agencies and by private industry. The team evaluated the potentials of research activities sponsored by DOE and by corporate funding to achieve projected high-efficiency goals and developed summary statements regarding industry expectations. Recommendations are made for the direction of future work to address specific unresolved aspects of multijunction cell technology.

[Teaching and learning the science of qualitative research in the health area].

PubMed

Calderón, Carlos

2012-03-01

Qualitative research constitutes a necessary perspective of knowledge within the field of health services. Healthcare always occurs in complex contexts and its enhancement requires research methodologies that address this complexity. Nevertheless, the knowledge and use of qualitative research in health services is still very limited. Among the different factors that affect its development, the teaching and learning of qualitative research proves to be fundamental, even beyond undergraduate education. Healthcare professionals and health services present certain specific aspects that must be considered in the design and development of the teaching and learning of qualitative research. Based on an eight-year online training experience with Primary Healthcare professionals, the main challenges are indentified and discussed.

Mitigating Issues Related to the Modeling of Insurgent Recruitment

NASA Astrophysics Data System (ADS)

Briscoe, Erica; Trewhitt, Ethan; Weiss, Lora; Whitaker, Elizabeth

Modeling the specific motivations and influences related to an individual's decision to become involved in insurgent warfare presents its own collection of unique challenges. The difficulty of the problem often necessitates simplifications that, while making the task more manageable, may inadvertently 'smooth away' critical aspects of the problem. Augmenting the challenge is that research into the motivations of terrorism has found there is not a definitive set of variables that serve as reliable indicators of an individual's involvement. This paper addresses techniques aimed toward mitigating issues that manifest in the modeling of insurgent recruitment so that these complications do not lessen the viability of models that are used in the prediction and evaluation of terrorist activity.

The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms

PubMed Central

Reed, David L.; Currier, Russell W.; Walton, Shelley F.; Conrad, Melissa; Sullivan, Steven A.; Carlton, Jane M.; Read, Timothy D.; Severini, Alberto; Tyler, Shaun; Eberle, R.; Johnson, Welkin E.; Silvestri, Guido; Clarke, Ian N.; Lagergård, Teresa; Lukehart, Sheila A.; Unemo, Magnus; Shafer, William M.; Beasley, R. Palmer; Bergström, Tomas; Norberg, Peter; Davison, Andrew J.; Sharp, Paul M.; Hahn, Beatrice H.; Blomberg, Jonas

2013-01-01

The following series of concise summaries addresses the evolution of infectious agents in relation to sex in animals and humans from the perspective of three specific questions: (1) what have we learned about the likely origin and phylogeny, up to the establishment of the infectious agent in the genital econiche, including the relative frequency of its sexual transmission; (2) what further research is needed to provide additional knowledge on some of these evolutionary aspects; and (3) what evolutionary considerations might aid in providing novel approaches to the more practical clinical and public health issues facing us currently and in the future? PMID:21824167

Integrative Approaches in Pediatric Palliative Care.

PubMed

Shafto, Kate; Gouda, Suzanne; Catrine, Kris; Brown, Melanie L

2018-06-13

Pediatric palliative care is a field which focuses on caring for and treating the symptoms and distress typically associated with life-limiting illness. Integrative medicine is supported by evidence and aims to heal the whole person, including all aspects of one’s lifestyle. Therapies offered by integrative medicine often empower patients and families, allowing for a sense of control. This review addresses the merging of integrative medicine philosophy and modalities with the care given to children with life-limiting illness. We review an introduction to integrative medicine, trends in its incorporation in the healthcare setting, application to patients receiving palliative care and the management of specific symptoms. A case study is offered to illustrate these principles.

Electronics reliability and measurement technology

NASA Technical Reports Server (NTRS)

Heyman, Joseph S. (Editor)

1987-01-01

A summary is presented of the Electronics Reliability and Measurement Technology Workshop. The meeting examined the U.S. electronics industry with particular focus on reliability and state-of-the-art technology. A general consensus of the approximately 75 attendees was that "the U.S. electronics industries are facing a crisis that may threaten their existence". The workshop had specific objectives to discuss mechanisms to improve areas such as reliability, yield, and performance while reducing failure rates, delivery times, and cost. The findings of the workshop addressed various aspects of the industry from wafers to parts to assemblies. Key problem areas that were singled out for attention are identified, and action items necessary to accomplish their resolution are recommended.

MPEG-21 in broadcasting: the novel digital broadcast item model

NASA Astrophysics Data System (ADS)

Lugmayr, Artur R.; Touimi, Abdellatif B.; Kaneko, Itaru; Kim, Jong-Nam; Alberti, Claudio; Yona, Sadigurschi; Kim, Jaejoon; Andrade, Maria Teresa; Kalli, Seppo

2004-05-01

The MPEG experts are currently developing the MPEG-21 set of standards and this includes a framework and specifications for digital rights management (DRM), delivery of quality of services (QoS) over heterogeneous networks and terminals, packaging of multimedia content and other things essential for the infrastructural aspects of multimedia content distribution. Considerable research effort is being applied to these new developments and the capabilities of MPEG-21 technologies to address specific application areas are being investigated. One such application area is broadcasting, in particular the development of digital TV and its services. In more practical terms, digital TV addresses networking, events, channels, services, programs, signaling, encoding, bandwidth, conditional access, subscription, advertisements and interactivity. MPEG-21 provides an excellent framework of standards to be applied in digital TV applications. Within the scope of this research work we describe a new model based on MPEG-21 and its relevance to digital TV: the digital broadcast item model (DBIM). The goal of the DBIM is to elaborate the potential of MPEG-21 for digital TV applications. Within this paper we focus on a general description of the DBIM, quality of service (QoS) management and metadata filtering, digital rights management and also present use-cases and scenarios where the DBIM"s role is explored in detail.

Fermented Food and Non-Communicable Chronic Diseases: A Review.

PubMed

Gille, Doreen; Schmid, Alexandra; Walther, Barbara; Vergères, Guy

2018-04-04

Fermented foods represent a significant fraction of human diets. Although their impact on health is positively perceived, an objective evaluation is still missing. We have, therefore, reviewed meta-analyses of randomized controlled trials (RCT) investigating the relationship between fermented foods and non-transmissible chronic diseases. Overall, after summarizing 25 prospective studies on dairy products, the association of fermented dairy with cancer was found to be neutral, whereas it was weakly beneficial, though inconsistent, for specific aspects of cardio-metabolic health, in particular stroke and cheese intake. The strongest evidence for a beneficial effect was for yoghurt on risk factors of type 2 diabetes. Although mechanisms explaining this association have not been validated, an increased bioavailability of insulinotropic amino acids and peptides as well as the bacterial biosynthesis of vitamins, in particular vitamin K2, might contribute to this beneficial effect. However, the heterogeneity in the design of the studies and the investigated foods impedes a definitive assessment of these associations. The literature on fermented plants is characterized by a wealth of in vitro data, whose positive results are not corroborated in humans due to the absence of RCTs. Finally, none of the RCTs were specifically designed to address the impact of food fermentation on health. This question should be addressed in future human studies.

Fermented Food and Non-Communicable Chronic Diseases: A Review

PubMed Central

Gille, Doreen; Schmid, Alexandra; Walther, Barbara; Vergères, Guy

2018-01-01

Fermented foods represent a significant fraction of human diets. Although their impact on health is positively perceived, an objective evaluation is still missing. We have, therefore, reviewed meta-analyses of randomized controlled trials (RCT) investigating the relationship between fermented foods and non-transmissible chronic diseases. Overall, after summarizing 25 prospective studies on dairy products, the association of fermented dairy with cancer was found to be neutral, whereas it was weakly beneficial, though inconsistent, for specific aspects of cardio-metabolic health, in particular stroke and cheese intake. The strongest evidence for a beneficial effect was for yoghurt on risk factors of type 2 diabetes. Although mechanisms explaining this association have not been validated, an increased bioavailability of insulinotropic amino acids and peptides as well as the bacterial biosynthesis of vitamins, in particular vitamin K2, might contribute to this beneficial effect. However, the heterogeneity in the design of the studies and the investigated foods impedes a definitive assessment of these associations. The literature on fermented plants is characterized by a wealth of in vitro data, whose positive results are not corroborated in humans due to the absence of RCTs. Finally, none of the RCTs were specifically designed to address the impact of food fermentation on health. This question should be addressed in future human studies. PMID:29617330

Optimal in vitro fertilization in 2020 should reduce treatment burden and enhance care delivery for patients and staff.

PubMed

Gameiro, Sofia; Boivin, Jacky; Domar, Alice

2013-08-01

This review argues that optimal in vitro fertilization in 2020 should include a way of enhancing the delivery of treatment for patients and staff by the minimization of patient, treatment, and clinic sources of burden. Two specific sources of burden are addressed. First, patient vulnerability can be tackled by implementation of pretreatment evidence-based screening for psychological distress, appropriate referral for support, elimination of barriers to acceptance of psychosocial support, and implementation of a routine care flowchart that identifies the specific stages of treatment when psychosocial support should be provided. Second, negative patient-staff interactions can be avoided by training staff in communication/interaction skills, promoting shared decision making, prioritizing psychological interventions that address aspects of care equally problematic for patients and staff, and monitoring the impact of change on patient, staff, and clinic outcomes. In addition, optimal in vitro fertilization should ensure now that the future generations of young adults know what "achieving parenthood" actually entails in the context of the many desired goals of adulthood, greater variety of reproductive techniques available, later age of first births, and, consequently, longer exposure to risk factors (e.g., smoking) that affect fertility. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Modeling of Broadband Liners Applied to the Advanced Noise Control Fan

NASA Technical Reports Server (NTRS)

Nark, Douglas M.; Jones, Michael G.; Sutliff, Daniel L.

2015-01-01

The broadband component of fan noise has grown in relevance with an increase in bypass ratio and incorporation of advanced fan designs. Therefore, while the attenuation of fan tones remains a major factor in engine nacelle acoustic liner design, the simultaneous reduction of broadband fan noise levels has received increased interest. As such, a previous investigation focused on improvements to an established broadband acoustic liner optimization process using the Advanced Noise Control Fan (ANCF) rig as a demonstrator. Constant-depth, double-degree of freedom and variable-depth, multi-degree of freedom liner designs were carried through design, fabrication, and testing. This paper addresses a number of areas for further research identified in the initial assessment of the ANCF study. Specifically, incident source specification and uncertainty in some aspects of the predicted liner impedances are addressed. This information is incorporated in updated predictions of the liner performance and comparisons with measurement are greatly improved. Results illustrate the value of the design process in concurrently evaluating the relative costs/benefits of various liner designs. This study also provides further confidence in the integrated use of duct acoustic propagation/radiation and liner modeling tools in the design and evaluation of novel broadband liner concepts for complex engine configurations.

Improving Schools, Improving School Health Education, Improving Public Health: The Role of SOPHE Members.

PubMed

Birch, David A

2017-12-01

The reciprocal relationship between health and education has garnered increased attention among public health professionals. The evidence is clear that the level of an individual's education is related to health outcomes in adulthood and that healthier children are more likely to be academically successful than those with health issues. Unpacking and examining various aspects of this relationship is the focus of my 2017 SOHE Presidential Address. The three specific purposes of the presentation are to (a) understand the reciprocal relationship between education and health, (b) understand the characteristics of quality schools and quality school health education, and (c) to review strategies designed to activate school improvement as a public health strategy. In order to examine the relationship, I will address the relationship of social determinants and social justice to the quality of education with special attention to the impact of poverty. In addition, I will present possible reasons behind the linkage of higher educational attainment to better health outcomes, and the impact of health challenges on academic success for school-age children and youth. Finally, I will present characteristics of quality schools including considerations related to quality school health education programs. I conclude the presentation by presenting 11 specific actions for school improvement for consideration by SOPHE members and other public health professionals.

Programming in a proposed 9X distributed Ada

NASA Technical Reports Server (NTRS)

Waldrop, Raymond S.; Volz, Richard A.; Goldsack, Stephen J.; Holzbach-Valero, A. A.

1991-01-01

The studies of the proposed Ada 9X constructs for distribution, now referred to as AdaPT are reported. The goals for this time period were to revise the chosen example scenario and to begin studying about how the proposed constructs might be implemented. The example scenario chosen is the Submarine Combat Information Center (CIC) developed by IBM for the Navy. The specification provided by IBM was preliminary and had several deficiencies. To address these problems, some changes to the scenario specification were made. Some of the more important changes include: (1) addition of a system database management function; (2) addition of a fourth processing unit to the standard resources; (3) addition of an operator console interface function; and (4) removal of the time synchronization function. To implement the CIC scenario in AdaPT, the decided strategy were publics, partitions, and nodes. The principle purpose for implementing the CIC scenario was to demonstrate how the AdaPT constructs interact with the program structure. While considering ways that the AdaPt constructs might be translated to Ada 83, it was observed that the partition construct could reasonably be modeled as an abstract data type. Although this gives a useful method of modeling partitions, it does not at all address the configuration aspects on the node construct.

Derivation of habitat-specific dissolved oxygen criteria for Chesapeake Bay and its tidal tributaries

USGS Publications Warehouse

Batiuk, Richard A.; Breitburg, Denise L.; Diaz, Robert J.; Cronin, Thomas M.; Secor, David H.; Thursby, Glen

2009-01-01

The Chesapeake 2000 Agreement committed its state and federal signatories to “define the water quality conditions necessary to protect aquatic living resources” in the Chesapeake Bay (USA) and its tidal tributaries. Hypoxia is one of the key water quality issues addressed as a result of the above Agreement. This paper summarizes the protection goals and specific criteria intended to achieve those goals for addressing hypoxia. The criteria take into account the variety of Bay habitats and the tendency towards low dissolved oxygen in some areas of the Bay. Stressful dissolved oxygen conditions were characterized for a diverse array of living resources of the Chesapeake Bay by different aquatic habitats: migratory fish spawning and nursery, shallow-water, open-water, deep-water, and deep-channel. The dissolved oxygen criteria derived for each of these habitats are intended to protect against adverse effects on survival, growth, reproduction and behavior. The criteria accommodate both spatial and temporal aspects of low oxygen events, and have been adopted into the Chesapeake Bay states – Maryland, Virginia, and Delaware – and the District of Columbia's water quality standards regulations. These criteria, now in the form of state regulatory standards, are driving an array of land-based and wastewater pollution reduction actions across the six-watershed.

The EURO-URHIS 2 project in Ho Chi Min City: contextual adequacy in cross-cultural research.

PubMed

Steels, Stephanie Linawati

2016-03-01

The European Urban Health Indicators System Project Part 2 (EURO-URHIS 2) is a cross-national study that was implemented in Europe. It consists of four data collection tools that were specifically developed to collect health data at an urban level. This paper reviews some of the methodological constraints in adapting the EURO-URHIS 2 study in Ho Chi Minh City, Vietnam. No attempt to extend the original study beyond Europe has been reported before. Cultural, political, economic and social differences create specific obstacles as well as challenges. This paper sets out how these challenges were addressed, examining key aspects of the methodology, including study design, translation of the questionnaire and data collection. It was found that the EURO-URHIS 2 adult data collection tool methodology could not be replicated in Vietnam. A lack of basic infrastructure and population registers led to significant changes being made to the sampling and survey administration. It was recommended that the Expanded Programme on Immunization (EPI) was used as the replacement method. Despite the limitations in using the EPI method, the overall strengths and benefits were found to address methodological issues and the resource poor setting. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

NASA Software Documentation Standard

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as "Standard") is designed to support the documentation of all software developed for NASA; its goal is to provide a framework and model for recording the essential information needed throughout the development life cycle and maintenance of a software system. The NASA Software Documentation Standard can be applied to the documentation of all NASA software. The Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. The basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

PubMed Central

Vanhollebeke, Benoit; Stone, Oliver A; Bostaille, Naguissa; Cho, Chris; Zhou, Yulian; Maquet, Emilie; Gauquier, Anne; Cabochette, Pauline; Fukuhara, Shigetomo; Mochizuki, Naoki; Nathans, Jeremy; Stainier, Didier YR

2015-01-01

Despite the critical role of endothelial Wnt/β-catenin signaling during central nervous system (CNS) vascularization, how endothelial cells sense and respond to specific Wnt ligands and what aspects of the multistep process of intra-cerebral blood vessel morphogenesis are controlled by these angiogenic signals remain poorly understood. We addressed these questions at single-cell resolution in zebrafish embryos. We identify the GPI-anchored MMP inhibitor Reck and the adhesion GPCR Gpr124 as integral components of a Wnt7a/Wnt7b-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis. We further show that this atypical Wnt/β-catenin signaling pathway selectively controls endothelial tip cell function and hence, that mosaic restoration of single wild-type tip cells in Wnt/β-catenin-deficient perineural vessels is sufficient to initiate the formation of CNS vessels. Our results identify molecular determinants of ligand specificity of Wnt/β-catenin signaling and provide evidence for organ-specific control of vascular invasion through tight modulation of tip cell function. DOI: http://dx.doi.org/10.7554/eLife.06489.001 PMID:26051822

Integrated analysis of RNA-binding protein complexes using in vitro selection and high-throughput sequencing and sequence specificity landscapes (SEQRS).

PubMed

Lou, Tzu-Fang; Weidmann, Chase A; Killingsworth, Jordan; Tanaka Hall, Traci M; Goldstrohm, Aaron C; Campbell, Zachary T

2017-04-15

RNA-binding proteins (RBPs) collaborate to control virtually every aspect of RNA function. Tremendous progress has been made in the area of global assessment of RBP specificity using next-generation sequencing approaches both in vivo and in vitro. Understanding how protein-protein interactions enable precise combinatorial regulation of RNA remains a significant problem. Addressing this challenge requires tools that can quantitatively determine the specificities of both individual proteins and multimeric complexes in an unbiased and comprehensive way. One approach utilizes in vitro selection, high-throughput sequencing, and sequence-specificity landscapes (SEQRS). We outline a SEQRS experiment focused on obtaining the specificity of a multi-protein complex between Drosophila RBPs Pumilio (Pum) and Nanos (Nos). We discuss the necessary controls in this type of experiment and examine how the resulting data can be complemented with structural and cell-based reporter assays. Additionally, SEQRS data can be integrated with functional genomics data to uncover biological function. Finally, we propose extensions of the technique that will enhance our understanding of multi-protein regulatory complexes assembled onto RNA. Copyright © 2016 Elsevier Inc. All rights reserved.

Three images of interdisciplinary team meetings.

PubMed

Crepeau, E B

1994-08-01

Teams are an essential aspect of health care today, especially in rehabilitation or chronic illness where the course of care is frequently long, complex, and unpredictable. The coordinative function of teams and their interdisciplinary aspects are thought to improve patient care because team members bring their unique professional skills together to address patient problems. This coordination is enacted through the team meeting, which typically results in an integrated care plan. This professional image of team meetings is explicit and addresses the description and provision of care as objective and rational activities. In contrast, the constructed and ritualistic images of health care team meetings are implicit and concern the less objective and rational aspects of planning care. The constructed image pertains to the definitional activity of team members as they try to understand patient troubles and achieve consensus. This process involves the individual clinical reasoning of team members and the collective reasoning of the group. The ritualistic image is that aspect of team meetings in which the team affirms and reaffirms its collective identity. Drawing from field research of geropsychiatric team meetings, this article defines and explicates these images, focusing on the constructed and ritualistic aspects of team meetings and the influence of these images on group function.

Do Parent Education Programs Promote Healthy Post-Divorce Parenting? Critical Distinctions and a Review of the Evidence

PubMed Central

Sigal, Amanda; Sandler, Irwin; Wolchik, Sharlene; Braver, Sanford

2009-01-01

Most parent education programs are designed to improve child well-being following divorce by changing some aspect of parenting. However, there has been relatively little discussion of what aspects of parenting are most critical and the effectiveness of programs to change different aspects of parenting. This paper addresses these issues by: 1. Distinguishing three aspects of post-divorce parenting that have been targeted in parent education programs; 2. Reviewing evidence of the relations between each aspect of parenting and the well-being of children and; 3. Critically reviewing evidence that parent education programs have been successful in changing each aspect of post-divorce parenting. PMID:21552360

Research and Clinical Center for Child Development Annual Report, 1984-1985.

ERIC Educational Resources Information Center

Miyake, Kazuo, Ed.

The seven articles in this annual report concern aspects of attachment, social interaction among parents and children, temperament, affective behavior, and/or research methodology. Aspects of attachment and temperament are addressed in Kazuo Miyake's study of the "Relation of Temperamental Disposition to Classification of Attachment,"…

School Culture and Physical Activity: A Systematic Review

ERIC Educational Resources Information Center

Rickwood, Greg

2013-01-01

This review examines literature on aspects of school culture and students' physical activity participation. The following questions were addressed: (1) what aspects of school culture have been examined in relation to physical activity, (2) what is the weight of evidence concerning the relationships between school culture factors and physical…

Resilience thinking: integrating resilience, adaptability and transformability

Treesearch

Carl Folke; Stephen R. Carpenter; Brian Walker; Marten Scheffer; Terry Chapin; Johan Rockstrom

2010-01-01

Resilience thinking addresses the dynamics and development of complex social-ecological systems (SES). Three aspects are central: resilience, adaptability and transformability. These aspects interrelate across multiple scales. Resilience in this context is the capacity of a SES to continually change and adapt yet remain within critical thresholds. Adaptability is part...

Regulatory Aspects of Smart Water Networks in the U.S.

EPA Science Inventory

The presentation addresses regulatory aspects of smart water networks in the U.S. It will be presented at the Smart Water Networks Forum (SWAN) annual conference in London, England from April 29-30, 2015. The conference will bring together key voices in the smart water space f...

The Practical Aspects of Online Counseling: Ethics, Training, Technology, and Competency

ERIC Educational Resources Information Center

Mallen, Michael J.; Vogel, David L.; Rochlen, Aaron B.

2005-01-01

This article addresses the practical aspects of online counseling, including ethics, training, supervision, technology, and competency issues. The authors discuss online counseling's strengths and limitations and present guidelines for what types of clients and counseling psychologists may be appropriate for online counseling. To illustrate the…

Addressing Air, Land & Water Nitrogen Issues under Changing Climate Trends & Variability

EPA Science Inventory

The climate of western U.S. dairy producing states is anticipated to change significantly over the next 50 to 75 years. A multimedia modeling system based upon the “nitrogen cascade” concept has been configured to address three aspects of sustainability (environmenta...

Standardization of the Definitions of Vertical Resolution and Uncertainty in the NDACC-archived Ozone and Temperature Lidar Measurements

NASA Technical Reports Server (NTRS)

Leblanc, T.; Godin-Beekmann, S.; Payen, Godin-Beekmann; Gabarrot, Franck; vanGijsel, Anne; Bandoro, J.; Sica, R.; Trickl, T.

2012-01-01

The international Network for the Detection of Atmospheric Composition Change (NDACC) is a global network of high-quality, remote-sensing research stations for observing and understanding the physical and chemical state of the Earth atmosphere. As part of NDACC, over 20 ground-based lidar instruments are dedicated to the long-term monitoring of atmospheric composition and to the validation of space-borne measurements of the atmosphere from environmental satellites such as Aura and ENVISAT. One caveat of large networks such as NDACC is the difficulty to archive measurement and analysis information consistently from one research group (or instrument) to another [1][2][3]. Yet the need for consistent definitions has strengthened as datasets of various origin (e.g., satellite and ground-based) are increasingly used for intercomparisons, validation, and ingested together in global assimilation systems.In the framework of the 2010 Call for Proposals by the International Space Science Institute (ISSI) located in Bern, Switzerland, a Team of lidar experts was created to address existing issues in three critical aspects of the NDACC lidar ozone and temperature data retrievals: signal filtering and the vertical filtering of the retrieved profiles, the quantification and propagation of the uncertainties, and the consistent definition and reporting of filtering and uncertainties in the NDACC- archived products. Additional experts from the satellite and global data standards communities complement the team to help address issues specific to the latter aspect.

Spatiotemporal & Ecological Processes Associated With Goliath Grouper Aggregations in Southeastern Florida

NASA Astrophysics Data System (ADS)

Binder, B. M.; Boswell, K. M.

2016-02-01

The formation of Fish Spawning Aggregations (FSAs) is vital to the life history of many reef fishes, representing the only reproductive opportunity for many species. Unfortunately FSAs present a lucrative target for exploitation which has led to cases of decline and regional extirpation. However, the integration of stakeholders into the design of fisheries management strategies has led to the protection of several species throughout the Greater Caribbean; including the goliath grouper, which has shown evidence of recovery since the moratorium on harvest in 1990. Since the closure, user based and researcher driven initiatives have investigated the recovery, biology, and life history of goliath grouper, but fine scale spatiotemporal and community level aspects of aggregation formation have not been specifically addressed. Thus, we developed a novel two-tiered survey approach using scientific echosounders and diver visual surveys to characterize the spatiotemporal aspects of goliath grouper aggregations, along with the community response to aggregations at six aggregation sites near Jupiter, Florida. Acoustic transects and diver surveys were performed near peak lunar phases throughout the spawning season to quantify fluctuations in goliath grouper density and abundance during the season; and to characterize changes in local community structure in response to aggregation formation. The results from this study are being used to inform the development of resource management plans in South Florida; and addressing these questions will generate a framework to apply a novel research technique in other regions where knowledge of reproductive behavior is absent from the peer-reviewed literature.

Recommendations for age-appropriate education of children and adolescents with diabetes and their parents in the European Union.

PubMed

Martin, Delphine; Lange, Karin; Sima, Alexandra; Kownatka, Dagmar; Skovlund, Søren; Danne, Thomas; Robert, Jean-Jacques

2012-09-01

Education is the keystone of diabetes care, and structured self-management education is the key to a successful outcome. Existing guidelines provide comprehensive guidance on the various aspects of education and offer general and organizational principles of education, detailed curricula at different ages and stages of diabetes, and recommendations on models, methods, and tools to attain educative objectives. The International Society for Pediatric and Adolescent Diabetes guidelines give the most elaborate and detailed descriptions and recommendations on the practice of education, which other national guidelines address on specific aspects of education and care. The aim of the work package on education developed by Better Control in Paediatric and Adolescent Diabetes in the European Union: Working to Create Centers of Reference (SWEET) project was not to generate new guidelines but to evaluate how the existing guidelines were implemented in some pediatric diabetes reference centers. The SWEET members have completed a questionnaire that elaborates on the many aspects of delivery of education. This survey highlights a profound diversity of practices across centers in Europe, in terms of organization as well as the practices and the content of initial and continuing education. A toolbox is being developed within SWEET to facilitate exchanges on all aspects of education and to establish a process of validation of materials, tools, written structured age-adjusted programs, and evaluation procedures for the education of children and adolescents with diabetes. © 2012 John Wiley & Sons A/S.

Assessing the relevance of ecotoxicological studies for regulatory decision making.

PubMed

Rudén, Christina; Adams, Julie; Ågerstrand, Marlene; Brock, Theo Cm; Poulsen, Veronique; Schlekat, Christian E; Wheeler, James R; Henry, Tala R

2017-07-01

Regulatory policies in many parts of the world recognize either the utility of or the mandate that all available studies be considered in environmental or ecological hazard and risk assessment (ERA) of chemicals, including studies from the peer-reviewed literature. Consequently, a vast array of different studies and data types need to be considered. The first steps in the evaluation process involve determining whether the study is relevant to the ERA and sufficiently reliable. Relevance evaluation is typically performed using existing guidance but involves application of "expert judgment" by risk assessors. In the present paper, we review published guidance for relevance evaluation and, on the basis of the practical experience within the group of authors, we identify additional aspects and further develop already proposed aspects that should be considered when conducting a relevance assessment for ecotoxicological studies. From a regulatory point of view, the overarching key aspect of relevance concerns the ability to directly or indirectly use the study in ERA with the purpose of addressing specific protection goals and ultimately regulatory decision making. Because ERA schemes are based on the appropriate linking of exposure and effect estimates, important features of ecotoxicological studies relate to exposure relevance and biological relevance. Exposure relevance addresses the representativeness of the test substance, environmental exposure media, and exposure regime. Biological relevance deals with the environmental significance of the test organism and the endpoints selected, the ecological realism of the test conditions simulated in the study, as well as a mechanistic link of treatment-related effects for endpoints to the protection goal identified in the ERA. In addition, uncertainties associated with relevance should be considered in the assessment. A systematic and transparent assessment of relevance is needed for regulatory decision making. The relevance aspects also need to be considered by scientists when designing, performing, and reporting ecotoxicological studies to facilitate their use in ERA. Integr Environ Assess Manag 2017;13:652-663. © 2016 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC). © 2016 The Authors. Integrated Environmental Assessment and Management Published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

Air Force Human Systems Integration (HSI) in Test and Evaluation (T&E)

DTIC Science & Technology

2012-08-01

allow human aspects related to system design to be tested and evaluated. 15. SUBJECT TERMS Air Force, Human Systems Integration, HSI, Test and...Community that would allow human aspects related to system design to be tested and evaluated. The intent was to identify and develop means for greater...related documentation in order to monitor the human related aspects for system development and design . To address these work areas, the team adopted

PREFACE Preface

NASA Astrophysics Data System (ADS)

Houée-Levin, Chantal; Gauduel, Yann A.

2011-01-01

The purpose of the four day COST CM0603-MELUSYN Joint Meeting 'Damages induced in Biomolecules by Low and High Energy Radiations', held in March 2010 in Paris, France, was to create a timely forum for multi-disciplinary discussions related to the recent developments on biomolecular damage triggered by low or high energy ionising radiations (photons, relativistic particles and accelerated ions). Created in September 2007, the European network COST CM0603 'Free radicals in Chemical Biology' (http://www.chembiorad.inct.pl/index.php) gathers specialists of free radical chemistry, biochemistry and biology. It aims to promote a chemical biology approach for the investigation of free radical pathways of biological interest and the improvement of communication and exchange among neighbouring scientific fields, such as chemistry with several domains of life sciences, specifically addressing the real barriers of specialist language and tools. The MELUSYN network was born in January 2006. This French think-tank and task force involves about one hundred scientists and clinicians who contribute to the emerging interdisciplinary domain of advanced spatio-temporal radiation biomedicine. One important mission of the MELUSYN network is to explore and identify new medical fields to which the specificity of 3rd generation synchrotron sources could be applied, either by themselves or in synergy with other advanced radiation sources. The network also contributes to the organization of international multidisciplinary conferences. In the framework of experimental and theoretical approaches, the conference gathered together 50 scientists from both communities and addressed a number of highly relevant aspects of bioradical chemistry and radiation biology, considering classical and more advanced radiation sources (synchrotron, ultra-short particle bunches based on high power laser technologies, microbeams) operating in the broad energy range eV-MeV, classical or semi-quantum simulations of molecular radiation processes. Considering some physical, chemical and biological aspects of radical mechanisms, including their consequences in medicine (radiotherapy for instance), the selected contributions of this Special Issue provide guidance for future interdisciplinary developments. In this way, the multi-scale aspects of radiation based bioradical chemistry and radiation biology should be considered. We would like to express our thanks to all the authors for their time and genuine efforts, and to the reviewers for their fruitful comments during the preparation of this volume. Editors Chantal Houée-LevinUniversity of Paris Sud, Orsay, France COST logo Yann A GauduelEcole Polytechnique - ENS Techniques Avancées Palaiseau, France MELUSYN logo

A critical overview of non-aqueous capillary electrophoresis. Part I: mobility and separation selectivity.

PubMed

Kenndler, Ernst

2014-03-28

This two-part review critically gives an overview on the theoretical and practical advances in non-aqueous capillary electrophoresis (NACE) achieved over the recent five years. Part I starts out by reviewing the aspects relevant to electromigration in organic solvents and evaluates potential advantages of the latter in comparison to aqueous solvent systems. The crucial role of solubility for the species involved in CE - analytes and back ground electrolyte constituents - is discussed both for ionic and neutral compounds. The impact of organic solvents on the electrophoretic and electroosmotic mobility and on the ionization (pKa values) of weak acids and bases is highlighted. Special emphasis is placed on methanol, acetonitrile and mixtures of these solvents, being the most frequent employed media for NACE applications. In addition, also solvents less commonly used in NACE will be covered, including other alcohols, amides (formamide, N-methylformamide, N,N-dimethylformamide, N,N-dimethylacetamide), propylene carbonate, dimethylsulphoxide, and nitromethane. The discussions address the consequences of dramatic pKa shifts frequently seen for weak acids and bases, and the important contributions of medium-specific electroosmotic flow (EOF) to electromigration in nonaqueous media. Important for NACE, the role of the water content on pKa and mobility is analyzed. Finally, association phenomena rather specific to nonaqueous solvents (ion pairing, homo- and heteroconjugation) will be addressed, along with their potential advantages for the development of NACE separation protocols. It is pointed out that this review is not intended as a listing of all papers that have been published on NACE in the period mentioned above. It rather deals with general aspects of migration and selectivity in organic solvent systems, and discusses - critically - examples from the literature with particular interest to the topic. An analog discussion about the role of the solvent on efficiency will be presented in Part II. Copyright © 2014 Elsevier B.V. All rights reserved.

Should I stay or should I go? Motivational profiles of Danish seafaring officers and non-officers.

PubMed

Haka, Miia; Borch, Daniel F; Jensen, Chris; Leppin, Anja

2011-01-01

Other studies have shed light on specific types of seafarers' job stressors and job satisfaction. However, so far there have not been any systematic attempts to capture the motivational profile of seafarers when it comes to both work demands and work resources. The purpose of this study is to explore the motivational profiles of seafarers in the Danish merchant fleet by identifying factors which motivate or demotivate seafarers to stay in their specific profession. Furthermore, we examine if there is a difference in work motivators and demotivators between Danish seafaring officers and non-officers. Material and methods. A questionnaire was sent out to 560 Danish-speaking seafarers with a Danish postal address; 346 seafarers returned the questionnaire, equalling a 61% response rate. The work motivators which were identified were: duration of home leave, level of responsibility, and level of challenge. The main demotivating factors that were identified were: being away from home, shipping company´s HRM, and regulatory requirements. The results contribute to a deeper understanding of how seafarers perceive their occupation, and help to identify areas and aspects which might need change if employers want to retain their workforce in the long run. Overall, the results show that most of the job demands and job resources that seafarers perceive are psychosocial. When it comes to the best aspects of seafaring, over 70% of the answers were related to psychosocial factors rather than organizational or structural factors. In relation to the perceived worst aspects in seafaring, about 85% of the responses fell into psychosocial categories. The differences in the motivational profiles of officers and non-officers showed the importance of not only looking at the seafaring profession as a whole but also considering the different characteristics of various jobs onboard.

MO-E-BRE-01: Determination, Minimization and Communication of Uncertainties in Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Dyk, J; Palta, J; Bortfeld, T

2014-06-15

Medical Physicists have a general understanding of uncertainties in the radiation treatment process, both with respect to dosimetry and geometry. However, there is a desire to be more quantitative about uncertainty estimation. A recent International Atomic Energy Agency (IAEA) report (about to be published) recommends that we should be as “accurate as reasonably achievable, technical and biological factors being taken into account”. Thus, a single recommendation as a goal for accuracy in radiation therapy is an oversimplification. That report also suggests that individual clinics should determine their own level of uncertainties for their specific treatment protocols. The question is “howmore » do we implement this in clinical practice”? AAPM Monograph 35 (2011 AAPM Summer School) addressed many specific aspects of uncertainties in each of the steps of a course of radiation treatment. The intent of this symposium is: (1) to review uncertainty considerations in the entire radiation treatment process including uncertainty determination for each step and uncertainty propagation for the total process, (2) to consider aspects of robust optimization which optimizes treatment plans while protecting them against uncertainties, and (3) to describe various methods of displaying uncertainties and communicating uncertainties to the relevant professionals. While the theoretical and research aspects will also be described, the emphasis will be on the practical considerations for the medical physicist in clinical practice. Learning Objectives: To review uncertainty determination in the overall radiation treatment process. To consider uncertainty modeling and uncertainty propagation. To highlight the basic ideas and clinical potential of robust optimization procedures to generate optimal treatment plans that are not severely affected by uncertainties. To describe methods of uncertainty communication and display.« less

How to identify the key factors that affect driver perception of accident risk. A comparison between Italian and Spanish driver behavior.

PubMed

de Oña, Juan; de Oña, Rocio; Eboli, Laura; Forciniti, Carmen; Mazzulla, Gabriella

2014-12-01

Road crashes can be caused by different factors, including infrastructure, vehicles, and human variables. Many research studies have focused solely on identifying the key factors that cause road crashes. From these studies, it emerged that human factors have the most relevant impact on accident severity. More specifically, accident severity depends on several factors related directly to the driver, i.e., driving experience, driver's socio-economic characteristics, and driving behavior and attitudes. In this paper, we investigate driver behaviors and attitudes while driving and specifically focus on different methods for identifying the factors that most affect the driver's perception of accident risk. To this end, we designed and conducted a survey in two different European contexts: the city of Cosenza, which is located in the south of Italy, and the city of Granada, which is located in the south of Spain. Samples of drivers were contacted for their opinions on certain aspects of driving rules and attitudes while driving, and different types of questions were addressed to the drivers to assess their judgments of these aspects. Consequently, different methods of data analysis were applied to determine the aspects that heavily influence driver perception of accident risk. An experiment based on the stated preferences (SP) was carried out with the drivers, and the SP data were analyzed using an ordered probit (OP) model. Interesting findings emerged from different analyses of the data and from the comparisons among the data collected in the two different territorial contexts. We found that both Italian and Spanish drivers consider driving in an altered psychophysical state and violating the overtaking rules to be the most risky behaviors. Copyright © 2014 Elsevier Ltd. All rights reserved.

Self-regulated learning of basic arithmetic skills: a longitudinal study.

PubMed

Throndsen, Inger

2011-12-01

Several studies have examined young primary school children's use of strategies when solving simple addition and subtraction problems. Most of these studies have investigated students' strategy use as if they were isolated processes. To date, we have little knowledge about how math strategies in young students are related to other important aspects in self-regulated learning. The main purpose of this study was to examine relations between young primary school children's basic mathematical skills and their use of math strategies, their metacognitive competence and motivational beliefs, and to investigate how students with basic mathematics skills at various levels differ in respect to the different self-regulation components. The participants were comprised of 27 Year 2 students, all from the same class. The data were collected in three stages (autumn Year 2, spring Year 2, and autumn Year 3). The children's arithmetic skills were measured by age relevant tests, while strategy use, metacognitive competence, and motivational beliefs were assessed through individual interviews. The participants were divided into three performance groups; very good students, good students, and not-so-good students. Analyses revealed that young primary school children at different levels of basic mathematics skill may differ in several important aspects of self-regulated learning. Analyses revealed that a good performance in addition and subtraction was related not only to the children's use of advanced mathematics strategies, but also to domain-specific metacognitive competence, ability attribution for success, effort attribution for failure, and high perceived self-efficacy when using specific strategies. The results indicate that instructional efforts to facilitate self-regulated learning of basic arithmetic skills should address cognitive, metacognitive, and motivational aspects of self-regulation. This is particularly important for low-performing students. ©2010 The British Psychological Society.

A hierarchical-multiobjective framework for risk management

NASA Technical Reports Server (NTRS)

Haimes, Yacov Y.; Li, Duan

1991-01-01

A broad hierarchical-multiobjective framework is established and utilized to methodologically address the management of risk. United into the framework are the hierarchical character of decision-making, the multiple decision-makers at separate levels within the hierarchy, the multiobjective character of large-scale systems, the quantitative/empirical aspects, and the qualitative/normative/judgmental aspects. The methodological components essentially consist of hierarchical-multiobjective coordination, risk of extreme events, and impact analysis. Examples of applications of the framework are presented. It is concluded that complex and interrelated forces require an analysis of trade-offs between engineering analysis and societal preferences, as in the hierarchical-multiobjective framework, to successfully address inherent risk.

The mixing of particle clouds plunging into water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Angelini, S.; Theofanous, T.G.; Yuen, W.W.

This work addresses certain fundamental aspects of the premixing phase of steam explosions, At issue are the multifield interaction aspects under highly transient, multidimensional conditions, and in presence of strong phase changes. They are addressed in an experiment (the MAGICO-2000) involving well-characterized particle clouds mixing with water, and detailed measurements on both external and internal characteristics of the mixing zone. Both cold and hot (up to 1500{degrees}C) particle clouds are considered in conjunction with saturated and subcooled water pools. The PMALPHA code is used as an aid in interpreting the experimental results, and the exercise reveals good predictive capabilities formore » it.« less

Nature of Science, Scientific Inquiry, and Socio-Scientific Issues Arising from Genetics: A Pathway to Developing a Scientifically Literate Citizenry

NASA Astrophysics Data System (ADS)

Lederman, Norman G.; Antink, Allison; Bartos, Stephen

2014-02-01

The primary focus of this article is to illustrate how teachers can use contemporary socio-scientific issues to teach students about nature of scientific knowledge as well as address the science subject matter embedded in the issues. The article provides an initial discussion about the various aspects of nature of scientific knowledge that are addressed. It is important to remember that the aspects of nature of scientific knowledge are not considered to be a comprehensive list, but rather a set of important ideas for adolescent students to learn about scientific knowledge. These ideas have been advocated as important for secondary students by numerous reform documents internationally. Then, several examples are used to illustrate how genetically based socio-scientific issues can be used by teachers to improve students' understandings of the discussed aspects of nature of scientific knowledge.

Three Orders of Leadership Development: Abecedarian to Manager to Entrepreneur

ERIC Educational Resources Information Center

Webber, Charles F.; Scott, Shelleyann; Scott, Donald E.

2014-01-01

Purpose: The purpose was to highlight aspects of principals' work that are problematic and the degree to which they feel prepared to address those aspects. It profiles principals' pre-appointment learning. Research Methods: The study was conducted in Alberta with principals in the first three years of their appointments. A questionnaire was…

Performance Measurement in Helicopter Training and Operations.

ERIC Educational Resources Information Center

Prophet, Wallace W.

For almost 15 years, HumRRO Division No. 6 has conducted an active research program on techniques for measuring the flight performance of helicopter trainees and pilots. This program addressed both the elemental aspects of flying (i.e., maneuvers) and the mission- or goal-oriented aspects. A variety of approaches has been investigated, with the…

Exploring Metaskills of Knowledge-Creating Inquiry in Higher Education

ERIC Educational Resources Information Center

Muukkonen, Hanni; Lakkala, Minna

2009-01-01

The skills of knowledge-creating inquiry are explored as a challenge for higher education. The knowledge-creation approach to learning provides a theoretical tool for addressing them: In addition to the individual and social aspects in regulation of inquiry, the knowledge-creation approach focuses on aspects related to advancing shared objects of…

Analysis of Student Loan Special Rate Allowances and Servicing Costs.

ERIC Educational Resources Information Center

Technology Management, Inc., Cambridge, MA.

This document addresses two separate, though related aspects of the operation of the Guaranteed Student Loan Program (GSLP): (1) the mechanism for setting the special rate allowance (SRA); and (2) the effect of the operating requirements of the program on lender servicing costs. The study develops recommendations for improving both aspects of the…

Technical and Non-Technical Programme Students' Attitudes and Reasons for Plagiarism

ERIC Educational Resources Information Center

Harji, Madhubala Bava; Ismail, Zalina; Chetty, Thiba Naraina; Letchumanan, Krishnaveni

2017-01-01

To date, plagiarism continues to be a widespread problem in higher education. Deemed to be endemic, researchers continue to examine various aspects of plagiarism, including students' perception, practices, attitudes and reasons for plagiarism, in addressing this growing concern. Most studies, however, tend to examine these aspects independently.…

Motivational Aspects of Moral Learning and Progress

ERIC Educational Resources Information Center

Curren, Randall

2014-01-01

This article addresses a puzzle about moral learning concerning its social context and the potential for moral progress: Won't the social context of moral learning shape moral perceptions, beliefs, and motivation in ways that will inevitably "limit" moral cognition, motivation, and progress? It addresses the relationships between…

Population Education Accessions List. January-April 1997.

ERIC Educational Resources Information Center

United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

This bibliography addresses the subject of population education. Entries are categorized into three parts. Part 1, "Population Education," consists of titles of books and other documents addressing various aspects of population education arranged by country in the first section and general materials in the second section. Part 2,…

A "Mindful Rational Living" Approach for Addressing HIV in the School Setting

ERIC Educational Resources Information Center

Chenneville, Tiffany; St. John Walsh, Audra

2016-01-01

This paper describes a "mindful rational living" approach, which incorporates mindfulness techniques with rational emotive behavioral therapy strategies for addressing HIV in the school setting. The utility of this approach for attending to the physical, mental, and psychosocial aspects of school-based HIV prevention and treatment will…

78 FR 6260 - Proposed Amendment of Class E Airspace; Kingston, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-30

... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2011-0831... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

78 FR 18929 - Proposed Establishment of Class E Airspace; Boothbay, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2012-0792... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

75 FR 42631 - Proposed Establishment of Class E Airspace; Wolfeboro, NH

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-22

... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2010-0321... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

Inconclusive evidence of Juniperus virginiana recovery following sulfur pollution reductions

Treesearch

Paul G. Schaberg; Gary J. Hawley; Shelly A. Rayback; Joshua M. Halman; Alexandra M. Kosiba

2014-01-01

Thomas et al. (1) address a question of great scientific interest: have pollution reductions mandated by the Clean Air Act improved forest health and productivity? Although answers to this question are of great importance, various aspects of this work limit its ability to address this question.

Diversity and Leadership in a Changing World

ERIC Educational Resources Information Center

Eagly, Alice H.; Chin, Jean Lau

2010-01-01

Scholars of leadership have infrequently addressed the diversity of leaders and followers in terms of culture, gender, race and ethnicity, or sexual orientation. This omission has weakened the ability of research and theory to address some of the most provocative aspects of contemporary leadership, including (a) the limited access of individuals…

Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report.

PubMed

Wahidi, Momen M; Herth, Felix; Yasufuku, Kazuhiro; Shepherd, Ray Wesley; Yarmus, Lonny; Chawla, Mohit; Lamb, Carla; Casey, Kenneth R; Patel, Sheena; Silvestri, Gerard A; Feller-Kopman, David J

2016-03-01

Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lung masses. The many publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians. Rigorous methodology has been applied to provide a trustworthy evidence-based guideline and expert panel report. A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed specific topics on the technical aspects of EBUS-TBNA. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. References were screened for inclusion, and well-recognized document evaluation tools were used to assess the quality of included studies, to extract meaningful data, and to grade the level of evidence to support each recommendation or suggestion. Our systematic review and critical analysis of the literature on 15 PICO questions related to the technical aspects of EBUS-TBNA resulted in 12 statements: 7 evidence-based graded recommendations and 5 ungraded consensus-based statements. Three questions did not have sufficient evidence to generate a statement. Evidence on the technical aspects of EBUS-TBNA varies in strength but is satisfactory in certain areas to guide clinicians on the best conditions to perform EBUS-guided tissue sampling. Additional research is needed to enhance our knowledge regarding the optimal performance of this effective procedure. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Therapeutic Strategies against Cyclin E1-Amplified Ovarian Cancers

DTIC Science & Technology

2017-10-01

Ph.D. CONTRACTING ORGANIZATION: The Wistar Institute of Anatomy & Biology Philadelphia, PA 19104 REPORT DATE: October 2017 TYPE OF REPORT: Annual...ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER The Wistar Institute of Anatomy & Biology 3601 Spruce Street Philadelphia, PA...ovarian cancers that address different aspects of CCNE1 biology . In the first aim, based on our preliminary data, we hypothesize that HSP90

Genetic counseling and the ethical issues around direct to consumer genetic testing.

PubMed

Hawkins, Alice K; Ho, Anita

2012-06-01

Over the last several years, direct to consumer(DTC) genetic testing has received increasing attention in the public, healthcare and academic realms. DTC genetic testing companies face considerable criticism and scepticism,particularly from the medical and genetic counseling community. This raises the question of what specific aspects of DTC genetic testing provoke concerns, and conversely,promises, for genetic counselors. This paper addresses this question by exploring DTC genetic testing through an ethic allens. By considering the fundamental ethical approaches influencing genetic counseling (the ethic of care and principle-based ethics) we highlight the specific ethical concerns raised by DTC genetic testing companies. Ultimately,when considering the ethics of DTC testing in a genetic counseling context, we should think of it as a balancing act. We need careful and detailed consideration of the risks and troubling aspects of such testing, as well as the potentially beneficial direct and indirect impacts of the increased availability of DTC genetic testing. As a result it is essential that genetic counselors stay informed and involved in the ongoing debate about DTC genetic testing and DTC companies. Doing so will ensure that the ethical theories and principles fundamental to the profession of genetic counseling are promoted not just in traditional counseling sessions,but also on a broader level. Ultimately this will help ensure that the public enjoys the benefits of an increasingly genetic based healthcare system.

Conscientious objection: personal and professional ethics in the public square.

PubMed

Montgomery, Jonathan

2015-01-01

English law expects health professionals to have, and act upon, consciences, but formal conscience clauses are not the main legal recognition of this expectation. Rather, they should be regarded as an anomaly with roots in very specific political settlements between society and health professions, whose legitimacy is historically contingent, and as an aspect of the 'price' to be paid for securing services. There are sound reasons for the protection of conscientious discretion as an aspect of professional identify, but specific rights of personal conscientious objection are difficult to reconcile with legitimate public expectations of comprehensive and non-discriminatory services. Professional identities include moral commitments, such as the privileging of patient safety over administrative convenience. These should not be permitted to be overridden by personal moralities during the course of service delivery (as opposed to debating in the abstract what the proper courses of action should be). Consequently, formal conscientious objection clauses should be reduced to a minimum and regularly revisited. It is generally more satisfactory to address clashes between the personal moralities of professionals and public expectations through more flexible means, enabling accommodation of a plurality of views where possible but acknowledging that this is a matter of striking an appropriate balance. Employment law rather than healthcare law provides the best mechanism for regulating this process. © The Author [2015]. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

Helicopter roll control effectiveness criteria program summary

NASA Technical Reports Server (NTRS)

Heffley, Robert K.; Bourne, Simon M.; Mnich, Marc A.

1988-01-01

A study of helicopter roll control effectiveness is summarized for the purpose of defining military helicopter handling qualities requirements. The study is based on an analysis of pilot-in-the-loop task performance of several basic maneuvers. This is extended by a series of piloted simulations using the NASA Ames Vertical Motion Simulator and selected flight data. The main results cover roll control power and short-term response characteristics. In general the handling qualities requirements recommended are set in conjunction with desired levels of flight task and maneuver response which can be directly observed in actual flight. An important aspect of this, however, is that vehicle handling qualities need to be set with regard to some quantitative aspect of mission performance. Specific examples of how this can be accomplished include a lateral unmask/remask maneuver in the presence of a threat and an air tracking maneuver which recognizes the kill probability enhancement connected with decreasing the range to the target. Conclusions and recommendations address not only the handling qualities recommendations, but also the general use of flight simulators and the dependence of mission performance on handling qualities.

Molecular etiology of primary hyperoxaluria type 1: new directions for treatment.

PubMed

Danpure, Christopher J

2005-01-01

Primary hyperoxaluria type 1 (PH1) is a rare autosomal-recessive disorder caused by a deficiency of the liver-specific enzyme alanine:glyoxylate aminotransferase (AGT). AGT deficiency results in increased synthesis and excretion of the metabolic end-product oxalate and deposition of insoluble calcium oxalate in the kidney and urinary tract. Classic treatments for PH1 have tended to address the more distal aspects of the disease process (i.e. the symptoms rather than the causes). However, advances in the understanding of the molecular etiology of PH1 over the past decade have shifted attention towards the more proximal aspects of the disease process (i.e. the causes rather than the symptoms). The determination of the crystal structure of AGT has enabled the effects of some of the most important missense mutations in the AGXT gene to be rationalised in terms of AGT folding, dimerization and stability. This has opened up new possibilities for the design pharmacological agents that might counteract the destabilizing effects of these mutations and which might be of use for the treatment of a potentially life-threatening and difficult-to-treat disease.

Fluorescence resonance energy transfer analysis of escherichia coli RNA polymerase and polymerase-DNA complexes.

PubMed

Heyduk, T; Niedziela-Majka, A

Fluorescence resonance energy transfer (FRET) is a technique allowing measurements of atomic-scale distances in diluted solutions of macromolecules under native conditions. This feature makes FRET a powerful tool to study complicated biological assemblies. In this report we review the applications of FRET to studies of transcription initiation by Escherichia coli RNA polymerase. The versatility of FRET for studies of a large macromolecular assembly such as RNA polymerase is illustrated by examples of using FRET to address several different aspects of transcription initiation by polymerase. FRET has been used to determine the architecture of polymerase, its complex with single-stranded DNA, and the conformation of promoter fragment bound to polymerase. FRET has been also used as a binding assay to determine the thermodynamics of promoter DNA fragment binding to the polymerase. Functional conformational changes in the specificity subunit of polymerase responsible for the modulation of the promoter binding activity of the enzyme and the mechanistic aspects of the transition from the initiation to the elongation complex were also investigated. Copyright 2002 Wiley Periodicals, Inc.

An Implementation-Focused Bio/Algorithmic Workflow for Synthetic Biology.

PubMed

Goñi-Moreno, Angel; Carcajona, Marta; Kim, Juhyun; Martínez-García, Esteban; Amos, Martyn; de Lorenzo, Víctor

2016-10-21

As synthetic biology moves away from trial and error and embraces more formal processes, workflows have emerged that cover the roadmap from conceptualization of a genetic device to its construction and measurement. This latter aspect (i.e., characterization and measurement of synthetic genetic constructs) has received relatively little attention to date, but it is crucial for their outcome. An end-to-end use case for engineering a simple synthetic device is presented, which is supported by information standards and computational methods and focuses on such characterization/measurement. This workflow captures the main stages of genetic device design and description and offers standardized tools for both population-based measurement and single-cell analysis. To this end, three separate aspects are addressed. First, the specific vector features are discussed. Although device/circuit design has been successfully automated, important structural information is usually overlooked, as in the case of plasmid vectors. The use of the Standard European Vector Architecture (SEVA) is advocated for selecting the optimal carrier of a design and its thorough description in order to unequivocally correlate digital definitions and molecular devices. A digital version of this plasmid format was developed with the Synthetic Biology Open Language (SBOL) along with a software tool that allows users to embed genetic parts in vector cargoes. This enables annotation of a mathematical model of the device's kinetic reactions formatted with the Systems Biology Markup Language (SBML). From that point onward, the experimental results and their in silico counterparts proceed alongside, with constant feedback to preserve consistency between them. A second aspect involves a framework for the calibration of fluorescence-based measurements. One of the most challenging endeavors in standardization, metrology, is tackled by reinterpreting the experimental output in light of simulation results, allowing us to turn arbitrary fluorescence units into relative measurements. Finally, integration of single-cell methods into a framework for multicellular simulation and measurement is addressed, allowing standardized inspection of the interplay between the carrier chassis and the culture conditions.

Antigen-Specific Tolerance in Immunotherapy of Th2-Associated Allergic Diseases

PubMed Central

Smarr, Charles B.; Bryce, Paul J.; Miller, Stephen D.

2013-01-01

Allergic diseases are an increasing health concern, particularly in the developed world. The standard clinical approach to treatment of allergic disease focuses on allergen avoidance and symptom control but does little to address the underlying Th2 bias of disease. Specific immunotherapy (SIT) consisting of controlled administration of allergen, however, has been demonstrated to successfully induce desensitization and tolerance in an antigen-specific manner for a variety of Th2-mediated diseases. This review focuses on the mechanisms by which current SIT approaches induce tolerance as well as discussing attempts to modify the safety and efficacy of SIT. These refinements focus on three major aspects of SIT: the route of antigen administration, modification of the antigen to remove allergenic epitopes and reduce adverse events and choice of adjuvant used to induce tolerance and/or immune deviation from Th2 to Th1 and regulatory T cell (Treg) phenotypes. Synthesis of these recent developments in SIT provides considerable promise for more robust therapies with improved safety profiles to improve resolution of allergic disease and its associated costs. PMID:24099300

Guidance on validation and qualification of processes and operations involving radiopharmaceuticals.

PubMed

Todde, S; Peitl, P Kolenc; Elsinga, P; Koziorowski, J; Ferrari, V; Ocak, E M; Hjelstuen, O; Patt, M; Mindt, T L; Behe, M

2017-01-01

Validation and qualification activities are nowadays an integral part of the day by day routine work in a radiopharmacy. This document is meant as an Appendix of Part B of the EANM "Guidelines on Good Radiopharmacy Practice (GRPP)" issued by the Radiopharmacy Committee of the EANM, covering the qualification and validation aspects related to the small-scale "in house" preparation of radiopharmaceuticals. The aim is to provide more detailed and practice-oriented guidance to those who are involved in the small-scale preparation of radiopharmaceuticals which are not intended for commercial purposes or distribution. The present guideline covers the validation and qualification activities following the well-known "validation chain", that begins with editing the general Validation Master Plan document, includes all the required documentation (e.g. User Requirement Specification, Qualification protocols, etc.), and leads to the qualification of the equipment used in the preparation and quality control of radiopharmaceuticals, until the final step of Process Validation. A specific guidance to the qualification and validation activities specifically addressed to small-scale hospital/academia radiopharmacies is here provided. Additional information, including practical examples, are also available.

An ℋ∞ full information approach for the feedforward controller design of a large blended wing body flexible aircraft

NASA Astrophysics Data System (ADS)

Westermayer, C.; Schirrer, A.; Hemedi, M.; Kozek, M.

2013-12-01

An ℋ∞ full information feedforward design approach for longitudinal motion prefilter design of a large flexible blended wing body (BWB) aircraft is presented. An existing onset is extended such that specifications concerning command tracking, limited control energy, and manoeuvre load reduction can be addressed simultaneously. Therefore, the utilized design architecture is provided and manual tuning aspects are considered. In order to increase controller tuning efficiency, an automated tuning process based on several optimization criteria is proposed. Moreover, two design methodologies for the parameter-varying design case are investigated. The obtained controller is validated on a high-order nonlinear model, indicating the high potential of the presented approach for flexible aircraft control.

Radiation safety aspects of commercial high-speed flight transportation

NASA Technical Reports Server (NTRS)

Wilson, John W.; Nealy, John E.; Cucinotta, Francis A.; Shinn, Judy L.; Hajnal, Ferenc; Reginatto, Marcel; Goldhagen, Paul

1995-01-01

High-speed commercial flight transportation is being studied for intercontinental operations in the 21st century, the projected operational characteristics for these aircraft are examined, the radiation environment as it is now known is presented, and the relevant health issues are discussed. Based on a critical examination of the data, a number of specific issues need to be addressed to ensure an adequate knowledge of the ionizing radiation health risks of these aircraft operations. Large uncertainties in our knowledge of the physical fields for high-energy neutrons and multiply-charged ion components need to be reduced. Improved methods for estimating risks in prenatal exposure need to be developed. A firm basis for solar flare monitoring and forecasting needs to be developed with means of exposure abatement.

The International Liver Transplantation Society Living Donor Liver Transplant Recipient Guideline

PubMed Central

Miller, Charles M.; Quintini, Cristiano; Dhawan, Anil; Durand, Francois; Heimbach, Julie K.; Kim-Schluger, Hyung Leona; Kyrana, Eirini; Lee, Sung-Gyu; Lerut, Jan; Lo, Chung-Mau; Pomfret, Elizabeth Anne

2017-01-01

Abstract Living donor liver transplantation (LDLT) has been increasingly embraced around the world as an important strategy to address the shortage of deceased donor livers. The aim of this guideline, approved by the International Liver Transplantation Society (ILTS), is to provide a collection of expert opinions, consensus, and best practices surrounding LDLT. Recommendations were developed from an analysis of the National Library of Medicine living donor transplantation indexed literature using the Grading of Recommendations Assessment, Development and Evaluation methodology. Writing was guided by the ILTS Policy on the Development and Use of Practice Guidelines (www.ilts.org). Intended for use by physicians, these recommendations support specific approaches to the diagnostic, therapeutic, and preventive aspects of care of living donor liver transplant recipients. PMID:28437386

Ultra-High Dilutions and Homeopathy: Can They Be Explained without Non-Local Theory?

PubMed

Almirantis, Yannis; Tsitinidis, Konstantinos

2018-06-05

We discuss questions related to the 'Benveniste Affair', its consequences and broader issues in an attempt to understand homeopathy. Specifically, we address the following points: 1.:  The relationship between the experiments conducted by Benveniste, Montagnier, their collaborators and groups that independently tested their results, to 'traditional' homeopathy. 2.:  Possible non-local components such as 'generalised entanglement' as the basis of the homeopathic phenomenon and experimental evidence for them. 3.:  The capability of highly diluted homeopathic remedies to provoke tangible biological changes in whole organisms and cellular experimental systems. 4.:  Aspects of the similia principle related to the above. 5.:  Suggestions that can lead to experimental verifications of the non-local hypothesis in homeopathy. The Faculty of Homeopathy.

Sensory overload: A concept analysis.

PubMed

Scheydt, Stefan; Müller Staub, Maria; Frauenfelder, Fritz; Nielsen, Gunnar H; Behrens, Johann; Needham, Ian

2017-04-01

In the context of mental disorders sensory overload is a widely described phenomenon used in conjunction with psychiatric interventions such as removal from stimuli. However, the theoretical foundation of sensory overload as addressed in the literature can be described as insufficient and fragmentary. To date, the concept of sensory overload has not yet been sufficiently specified or analyzed. The aim of the study was to analyze the concept of sensory overload in mental health care. A literature search was undertaken using specific electronic databases, specific journals and websites, hand searches, specific library catalogues, and electronic publishing databases. Walker and Avant's method of concept analysis was used to analyze the sources included in the analysis. All aspects of the method of Walker and Avant were covered in this concept analysis. The conceptual understanding has become more focused, the defining attributes, influencing factors and consequences are described and empirical referents identified. The concept analysis is a first step in the development of a middle-range descriptive theory of sensory overload based on social scientific and stress-theoretical approaches. This specification may serve as a fundament for further research, for the development of a nursing diagnosis or for guidelines. © 2017 Australian College of Mental Health Nurses Inc.

Model Transformation for a System of Systems Dependability Safety Case

NASA Technical Reports Server (NTRS)

Murphy, Judy; Driskell, Stephen B.

2010-01-01

Software plays an increasingly larger role in all aspects of NASA's science missions. This has been extended to the identification, management and control of faults which affect safety-critical functions and by default, the overall success of the mission. Traditionally, the analysis of fault identification, management and control are hardware based. Due to the increasing complexity of system, there has been a corresponding increase in the complexity in fault management software. The NASA Independent Validation & Verification (IV&V) program is creating processes and procedures to identify, and incorporate safety-critical software requirements along with corresponding software faults so that potential hazards may be mitigated. This Specific to Generic ... A Case for Reuse paper describes the phases of a dependability and safety study which identifies a new, process to create a foundation for reusable assets. These assets support the identification and management of specific software faults and, their transformation from specific to generic software faults. This approach also has applications to other systems outside of the NASA environment. This paper addresses how a mission specific dependability and safety case is being transformed to a generic dependability and safety case which can be reused for any type of space mission with an emphasis on software fault conditions.

Rectenna session: Micro aspects. [energy conversion

NASA Technical Reports Server (NTRS)

Gutmann, R. J.

1980-01-01

Two micro aspects of the rectenna design are addressed: evaluation of the degradation in net rectenna RF to DC conversion efficiency due to power density variations across the rectenna (power combining analysis) and design of Yagi-Uda receiving elements to reduce rectenna cost by decreasing the number of conversion circuits (directional receiving elements). The first of these micro aspects involves resolving a fundamental question of efficiency potential with a rectenna, while the second involves a design modification with a large potential cost saving.

Criticism and Interpretation: Teaching the Persuasive Aspects of Research Articles

PubMed Central

Gillen, Christopher M.

2006-01-01

Research articles are an excellent tool for promoting active learning about the scientific process. One difficulty in teaching research articles is that they address a professional audience and often seek to be persuasive as well as informative. This essay discusses pedagogical strategies that are intended to help students differentiate the purely informative aspects of research articles, such as descriptions of the methods and results, from the persuasive aspects, such as interpretation of results and critical evaluation of the work of other scientists. PMID:17012188

Criticism and interpretation: teaching the persuasive aspects of research articles.

PubMed

Gillen, Christopher M

2006-01-01

Research articles are an excellent tool for promoting active learning about the scientific process. One difficulty in teaching research articles is that they address a professional audience and often seek to be persuasive as well as informative. This essay discusses pedagogical strategies that are intended to help students differentiate the purely informative aspects of research articles, such as descriptions of the methods and results, from the persuasive aspects, such as interpretation of results and critical evaluation of the work of other scientists.

A Response to Commentaries on "Music Matters: A Philosophy of Music Education," Second Edition (2015)

ERIC Educational Resources Information Center

Elliott, David J.; Silverman, Marissa

2015-01-01

This essay responds to five commentaries on "Music Matters: A Philosophy of Music Education," 2nd edition (2015). Because each author provides a substantial discussion of different aspects of the book, this essay does not attempt to address all points. Instead, we reflect on selected aspects of each scholar's critique.

Toward a Psychophysics of Agency: Detecting Gain and Loss of Control over Auditory Action Effects

ERIC Educational Resources Information Center

Repp, Bruno H.; Knoblich, Gunther

2007-01-01

Theories of agency--the feeling of being in control of one's actions and their effects--emphasize either perceptual or cognitive aspects. This study addresses both aspects simultaneously in a finger-tapping paradigm. The tasks required participants to detect when synchronization of their taps with computer-controlled tones changed to…

Deconstructing the "I" and "SLA" in ISLA: One Curricular Approach

ERIC Educational Resources Information Center

Leow, Ronald P.; Cerezo, Luis

2016-01-01

Instructed second language acquisition (ISLA) has been referenced in the larger field of the SLA literature for over two and a half decades. Currently, there are several theoretical underpinnings accounting for processes assumed to play a role in ISLA and quite an impressive number of studies have empirically addressed some aspect(s) of ISLA.…

Still Social and Democratic? Inclusive Education Policies in the Nordic Welfare States

ERIC Educational Resources Information Center

Arnesen, Anne-Lise; Lundahl, Lisbeth

2006-01-01

In this article, education policy is analyzed from a welfare state perspective. The aim is to Analise the significance attributed to social-inclusive aspects of education in contemporary education policies of the Nordic countries, and the extent to which education is regarded as an element in welfare policies. Four aspects are addressed: (1)…

Safety in the Chemical Laboratory. Epidemiology of Accidents in Academic Chemistry Laboratories, Part 2. Accident Intervention Study, Legal Aspects, and Observations.

ERIC Educational Resources Information Center

Hellmann, Margaret A.; And Others

1986-01-01

Reports on a chemistry laboratory accident intervention study conducted throughout the state of Colorado. Addresses the results of an initial survey of institutions of higher learning. Discusses some legal aspects concerning academic chemistry accidents. Provides some observations about academic chemistry laboratory accidents on the whole. (TW)

Modeling the cumulative watershed effects of forest management strategies

Treesearch

R. R. Ziemer; J. Lewis; R. M. Rice; T. E. Lisle

1991-01-01

Abstract - There is increasing concern over the possibility of adverse cumulative watershed effects from intensive forest management. It is impractical to address many aspects of the problem experimentally because to do so would require studying large watersheds for 100 yr or more. One such aspect is the long-term effect of forest management strategies on erosion and...

Can the EVIDEM Framework Tackle Issues Raised by Evaluating Treatments for Rare Diseases: Analysis of Issues and Policies, and Context-Specific Adaptation.

PubMed

Wagner, Monika; Khoury, Hanane; Willet, Jacob; Rindress, Donna; Goetghebeur, Mireille

2016-03-01

The multiplicity of issues, including uncertainty and ethical dilemmas, and policies involved in appraising interventions for rare diseases suggests that multicriteria decision analysis (MCDA) based on a holistic definition of value is uniquely suited for this purpose. The objective of this study was to analyze and further develop a comprehensive MCDA framework (EVIDEM) to address rare disease issues and policies, while maintaining its applicability across disease areas. Specific issues and policies for rare diseases were identified through literature review. Ethical and methodological foundations of the EVIDEM framework v3.0 were systematically analyzed from the perspective of these issues, and policies and modifications of the framework were performed accordingly to ensure their integration. Analysis showed that the framework integrates ethical dilemmas and issues inherent to appraising interventions for rare diseases but required further integration of specific aspects. Modification thus included the addition of subcriteria to further differentiate disease severity, disease-specific treatment outcomes, and economic consequences of interventions for rare diseases. Scoring scales were further developed to include negative scales for all comparative criteria. A methodology was established to incorporate context-specific population priorities and policies, such as those for rare diseases, into the quantitative part of the framework. This design allows making more explicit trade-offs between competing ethical positions of fairness (prioritization of those who are worst off), the goal of benefiting as many people as possible, the imperative to help, and wise use of knowledge and resources. It also allows addressing variability in institutional policies regarding prioritization of specific disease areas, in addition to existing uncertainty analysis available from EVIDEM. The adapted framework measures value in its widest sense, while being responsive to rare disease issues and policies. It provides an operationalizable platform to integrate values, competing ethical dilemmas, and uncertainty in appraising healthcare interventions.

Classroom Activities in State and Local Government. Bulletin No. 9446.

ERIC Educational Resources Information Center

Wisconsin State Dept. of Public Instruction, Madison.

Educating students about state and local government is vital to providing the skills necessary for effective citizenship. This six-part teachers guide addresses various aspects of incorporating the study of government into the social studies curriculum. Part 1 presents a rationale and goals for teaching government. Part 2 addresses the various…

Finishability of CCA pressure-treated wood

Treesearch

Alan Ross; Richard Carlson; William Feist; Steven Bussjaeger

2000-01-01

Thus, a need arose for the development of surface finishes for CCA-treated wood that could address the special requirements of this substrate and provide protection against the ravages of water, sunlight, mildew, and other aspects of weathering and wear. Initially, this need was not addressed, most wood preserving companies had little expertise in surface finishes and...

Reactions to Western Values as Reflected in African Novels.

ERIC Educational Resources Information Center

Brown, Ella

1987-01-01

Earlier African novels, addressed to a Western audience, defend the traditional culture of the authors and attack the hypocrisy of the West. Later novels, written after 1960, are addressed to an African audience, and present balanced appraisals of Western culture and religion. Discusses rhetorical devices and other aspects of African novels. (BJV)

Every Other Day. Keynote Address.

ERIC Educational Resources Information Center

Tiller, Tom

Schools need to be reoriented and restructured so that what is taught and learned, and the way in which it is taught and learned, are better integrated with young people's real-world experiences. Many indicators suggest that the meaningful aspects of school have been lost in the encounter with modern times. The title of this address--"Every…

Goddard Space Flight Center contributions to the University of California, Santa Cruz Summer Workshop on High Energy Transients

NASA Technical Reports Server (NTRS)

1983-01-01

Topics addressing the characteristics and emission mechanisms of gamma ray bursts and neutron and gamma ray emission from solar flares are discussed. In addition, observational aspects of gamma ray astronomy are addressed with particular attention given to optical transients associated with gamma ray bursts.

Serbo-Croatian. SC-15A. Part 3. Advanced Grammar and Syntax,

DTIC Science & Technology

1983-09-01

mislili smo, (mi) The second person designates the person whom the speaker is addressing. Sg. govoris, pevas , pises, pevao si (ti) PI. govorite, pevate...one who is addressed. Sg. govori (on or ona), peva , pise, je pevao (la) PI. govore, pevau, pisu, su pevali(le) (one, oni) II. Aspect Predicates: There

77 FR 20747 - Proposed Amendment of Class E Airspace; Billings, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... No. 12-ANM-1, at the beginning of your comments. You may also submit comments through the Internet at... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA 2012-0316... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

78 FR 33772 - Proposed Modification of Class E Airspace; Brigham City, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... No. 13-ANM-14, at the beginning of your comments. You may also submit comments through the Internet... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA 2013-0414... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

78 FR 11996 - Proposed Modification of Class D and Class E Airspace; Pueblo, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

... comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: Eldon Taylor... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA 2012-0371... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

Pathways to Leadership and Professional Development: Inspiring Novice Special Educators

ERIC Educational Resources Information Center

Kaufman, Roberta C.; Ring, Mary

2011-01-01

Well-trained new special education teachers know that the individualized education program (IEP) team is the crux of the special education program. The IEP team addresses academic goals and behavior intervention plans for the student but rarely addresses in depth the social environment of the school, classroom, or family. Important aspects of the…

Flipping the Misogynist Script: Gender, Agency, Hip Hop and Music Education

ERIC Educational Resources Information Center

Tobias, Evan S.

2014-01-01

Excluding Hip Hop culture and rap music from music education misses opportunities for addressing key aspects of popular culture, society, and students' lives. This article addresses intersections of Hip Hop, gender, and music education to forward potential Hip Hop praxis. After tracing related scholarship, I discuss and problematize…

The Challenge of the Community College to the Church.

ERIC Educational Resources Information Center

Hallman, W. E., Ed.

The ten essays presented in this collection address various aspects of the relationship of the church and the community college. In the first two essays, C. Freeman Sleeper examines the challenges posed by community colleges to the church's traditional support of higher education and, then, discusses approaches to addressing the moral issues…

The Call To Pay Attention to Family Diversity: Constructing a Response.

ERIC Educational Resources Information Center

Wallat, Cynthia; Steele, Carolyn I.

The objective of this paper is two-fold. First, to address continued criticism of a general lack of attention to diverse aspects of family development due to continued reliance on traditional ways of assessing and conceptualizing family interaction. Second, to address recent recommendations to educate professionals who are capable of promoting…

Nurse prescribing as an aspect of future role expansion: the views of Irish clinical nurse specialists.

PubMed

Lockwood, Emily B; Fealy, Gerard M

2008-10-01

Nurses and midwives are expanding the scope of their professional practice, assuming additional responsibilities including the management and prescribing of medications. The aim of the study was to discover the attitudes of clinical nurse specialists (CNSs) in Ireland to nurse prescribing and to examine perceived barriers to engaging in this aspect of future role expansion. The expansion of the nursing role in relation to nurse prescribing is an ongoing process and is subject to incremental iterations of legislation and professional policy. Nurse prescribing as an expanded role function has become a reality in many countries. Ireland has addressed the matter in a formal and systematic way through legislation. A questionnaire was administered to a sample of 283 CNSs practising in a variety of care settings in Ireland. Attitudes were measured using Likert-type attitudinal scales, designed specifically for the study. Findings indicate that the majority of clinical nurse specialists were positively disposed toward nurse prescribing as a future role expansion. The fear of litigation was identified as the most significant barrier to nurse prescribing. The majority of respondents equated nurse prescribing with increased autonomy and holistic care. The findings indicate that there is a need for further examination of the educational requirements of the CNS in relation to nurse prescribing. The legislative implications for nurse prescribing and fear of legal consequences need to be considered prior to any implementation of nurse prescribing. While senior clinicians are willing to embrace future role expansion in the area of nurse prescribing, their Nurse Managers should recognize that facilitation of nurse prescribing needs to address the legal and educational requirements for such activity. Failure to address these requirements can represent a barrier to role expansion. This paper offers new understandings on the views of senior clinicians concerning nurse prescribing at a time of ongoing professional policy iteration and practice change in the area.

Holistic approach to design and implementation of a medical teleconsultation workspace.

PubMed

Czekierda, Łukasz; Malawski, Filip; Wyszkowski, Przemysław

2015-10-01

While there are many state-of-the-art approaches to introducing telemedical services in the area of medical imaging, it is hard to point to studies which would address all relevant aspects in a complete and comprehensive manner. In this paper we describe our approach to design and implementation of a universal platform for imaging medicine which is based on our longstanding experience in this area. We claim it is holistic, because, contrary to most of the available studies it addresses all aspects related to creation and utilization of a medical teleconsultation workspace. We present an extensive analysis of requirements, including possible usage scenarios, user needs, organizational and security issues and infrastructure components. We enumerate and analyze multiple usage scenarios related to medical imaging data in treatment, research and educational applications - with typical teleconsultations treated as just one of many possible options. Certain phases common to all these scenarios have been identified, with the resulting classification distinguishing several modes of operation (local vs. remote, collaborative vs. non-interactive etc.). On this basis we propose a system architecture which addresses all of the identified requirements, applying two key concepts: Service Oriented Architecture (SOA) and Virtual Organizations (VO). The SOA paradigm allows us to decompose the functionality of the system into several distinct building blocks, ensuring flexibility and reliability. The VO paradigm defines the cooperation model for all participating healthcare institutions. Our approach is validated by an ICT platform called TeleDICOM II which implements the proposed architecture. All of its main elements are described in detail and cross-checked against the listed requirements. A case study presents the role and usage of the platform in a specific scenario. Finally, our platform is compared with similar systems described into-date studies and available on the market. Copyright © 2015. Published by Elsevier Inc.

Addressing social responsibility in medical education: the African way.

PubMed

Kwizera, Enoch N; Iputo, Jehu E

2011-01-01

Indigenous sub-Saharan societies have, over the millennia, lived and socialised within the unwritten 'rules' of the 'Ubuntu' or similar philosophies that emphasises holistic 'humanness', and which is a form of 'social responsibility'. This article looks into some relevant social responsibility aspects of medical education in the South African context, with particular emphasis on how these aspects have been addressed. Apartheid was, by its very nature, incompatible with social responsibility for the majority of South Africans, but one medical school that was a non-complicit product of apartheid succeeded in fulfilling a socially responsible mission. Thus, this article implicitly identifies what South Africa, Africa and the global Health Professions Education community could learn from these trail-blazing experiences.

Psychosocial aspects of rehabilitation in sports.

PubMed

Covassin, Tracey; Beidler, Erica; Ostrowski, Jennifer; Wallace, Jessica

2015-04-01

When an athlete is injured, the primary focus of the sports medicine team is to treat the physical effects of the injury. However, many injured athletes experience negative psychological responses that should also be addressed throughout the rehabilitation process. Sports medicine professions should use psychosocial skills to help decrease the negative consequences of the injury, such as fear of reinjury, anxiety, depression, and adherence to rehabilitation. These psychosocial skills include goal setting, imagery, relaxation techniques, motivation, and self-talk. This article addresses the negative consequences of injury, psychosocial skills used to aid in the rehabilitation process, and clinical implications of the psychological aspects of rehabilitation in sport. Copyright © 2015 Elsevier Inc. All rights reserved.

Mobile health requires mobile security: challenges, solutions, and standardization.

PubMed

Pharow, Peter; Blobel, Bernd

2008-01-01

Extended communication and advanced cooperation in a permanently growing healthcare and welfare domain require a well-defined set of security services provided by an interoperable security infrastructure based on international and European standards. Any communication and collaboration procedure requires a purpose. But such legal purpose-binding is definitely not the only aspect to carefully be observed and investigated. More and more, aspects of security, safety, privacy, ethics, and quality reach importance while discussing about future-proof health information systems and health networks - regardless whether local, regional or even pan-European networks. During the course of the current paradigm change from an organization-centered to a process-related and to a person-centered health system, different new technologies including mobile solutions need to be applied in order to meet challenges arising from both legal and technical circumstances. Beside the typical Information and Communication Technology systems and applications, the extended use of modern technologies includes large medical devices like, e.g., MRI and CT but also small devices like sensors worn by a person or included in clothing. Security and safety are on top of the priority list. The paper addresses the identification of some specific aspects like mobile technology and safety when moving both IT and people towards mobile health aiming at increasing citizens and patients awareness, confidence, and acceptance in future mobile care - a world often still beyond the horizon.

An examination of professional and ethical issues in the fellowship application process in pathology.

PubMed

Domen, Ronald E; Wehler, Amanda Brehm

2008-04-01

Approximately 34 medical specialty and subspecialty fellowship programs in the United States have formalized the application process through the National Resident Matching Program. This approach sets standards for the application process, offers a formalized match similar to that for residency programs, functions within a specific timeline, and establishes binding rules of behavior for both applicants and programs. For fellowship programs that operate outside the National Resident Matching Program, such as those in pathology, no published guidelines exist to help programs and applicants address the many questions and problems that can arise. As a result, programs are free to set their own timelines for interviews, application requirements, contract negotiations and finalizations, and other details. Consequently, applicants often feel pressured to apply earlier and earlier in their residency for competitive fellowship programs, are often required to fill out multiple unique applications, may feel no "loyalty" toward honoring an acceptance without a contract, and often feel disenfranchised by the whole process. This article addresses professional and ethical aspects of the current application process and offers possible solutions for improving it.

Recovery Housing: Evolving Models to Address Resident Needs.

PubMed

Mericle, Amy A; Polcin, Douglas L; Hemberg, Jordana; Miles, Jennifer

2017-01-01

Recovery housing is a service delivery modality that simultaneously addresses the social support and housing needs of those in recovery from substance use disorders. This article describes a group of recovery homes in Texas (N = 10) representing a lesser-studied type of recovery housing, one which explicitly bridges treatment and peer support by providing a variety of recovery support services. All residents meet with a recovery coach, undergo regular drug screening, and have access to intensive outpatient treatment-a program that was developed specifically to support the needs of residents in the homes. Unlike the Oxford House TM model and California sober living houses, which are primarily financed through resident fees, these homes are supported through a mix of resident fees as well as private and public insurance. While adhering to some aspects of the social model of recovery, none of these homes would meet criteria to be considered a true social model program, largely because residents have a limited role in the governance of the homes. Residences like the ones in this study are not well-represented in the literature and more research is needed.

Review of Global Change Research Program plan

NASA Astrophysics Data System (ADS)

Showstack, Randy

2012-01-01

The draft 10-year strategic plan for the U.S. Global Change Research Program (USGCRP), which proposes broadening the scope of the program from climate change only to climate change and climaterelated global changes, “is an important step in the right direction,” according to a 5 January review of the plan by a committee of the U.S. National Research Council (NRC) of the National Academies. However, the committee also said that the program's legislative mandate is even broader in allowing USGCRP to address many aspects of global change including climate change, the global hydrological cycle, and widespread land use changes. “The Program's legislative mandate is to address all of global change, whether or not related to climate. The Committee concurs that this broader scope is appropriate, but realizes that such an expansion may be constrained by budget realities and by the practical challenge of maintaining clear boundaries for an expanded program,” the report states. “We encourage sustained efforts to expand the Program over time, along with efforts to better define and prioritize what specific topics are included within the bounds of global change research.”

Getting to Evo-Devo: Concepts and Challenges for Students Learning Evolutionary Developmental Biology

PubMed Central

Hiatt, Anna; Davis, Gregory K.; Trujillo, Caleb; Terry, Mark; French, Donald P.; Price, Rebecca M.; Perez, Kathryn E.

2013-01-01

To examine how well biology majors have achieved the necessary foundation in evolution, numerous studies have examined how students learn natural selection. However, no studies to date have examined how students learn developmental aspects of evolution (evo-devo). Although evo-devo plays an increasing role in undergraduate biology curricula, we find that instruction often addresses development cursorily, with most of the treatment embedded within instruction on evolution. Based on results of surveys and interviews with students, we suggest that teaching core concepts (CCs) within a framework that integrates supporting concepts (SCs) from both evolutionary and developmental biology can improve evo-devo instruction. We articulate CCs, SCs, and foundational concepts (FCs) that provide an integrative framework to help students master evo-devo concepts and to help educators address specific conceptual difficulties their students have with evo-devo. We then identify the difficulties that undergraduates have with these concepts. Most of these difficulties are of two types: those that are ubiquitous among students in all areas of biology and those that stem from an inadequate understanding of FCs from developmental, cell, and molecular biology. PMID:24006397

Addressing uncertainty in atomistic machine learning.

PubMed

Peterson, Andrew A; Christensen, Rune; Khorshidi, Alireza

2017-05-10

Machine-learning regression has been demonstrated to precisely emulate the potential energy and forces that are output from more expensive electronic-structure calculations. However, to predict new regions of the potential energy surface, an assessment must be made of the credibility of the predictions. In this perspective, we address the types of errors that might arise in atomistic machine learning, the unique aspects of atomistic simulations that make machine-learning challenging, and highlight how uncertainty analysis can be used to assess the validity of machine-learning predictions. We suggest this will allow researchers to more fully use machine learning for the routine acceleration of large, high-accuracy, or extended-time simulations. In our demonstrations, we use a bootstrap ensemble of neural network-based calculators, and show that the width of the ensemble can provide an estimate of the uncertainty when the width is comparable to that in the training data. Intriguingly, we also show that the uncertainty can be localized to specific atoms in the simulation, which may offer hints for the generation of training data to strategically improve the machine-learned representation.

Modeling and measurement of fault-tolerant multiprocessors

NASA Technical Reports Server (NTRS)

Shin, K. G.; Woodbury, M. H.; Lee, Y. H.

1985-01-01

The workload effects on computer performance are addressed first for a highly reliable unibus multiprocessor used in real-time control. As an approach to studing these effects, a modified Stochastic Petri Net (SPN) is used to describe the synchronous operation of the multiprocessor system. From this model the vital components affecting performance can be determined. However, because of the complexity in solving the modified SPN, a simpler model, i.e., a closed priority queuing network, is constructed that represents the same critical aspects. The use of this model for a specific application requires the partitioning of the workload into job classes. It is shown that the steady state solution of the queuing model directly produces useful results. The use of this model in evaluating an existing system, the Fault Tolerant Multiprocessor (FTMP) at the NASA AIRLAB, is outlined with some experimental results. Also addressed is the technique of measuring fault latency, an important microscopic system parameter. Most related works have assumed no or a negligible fault latency and then performed approximate analyses. To eliminate this deficiency, a new methodology for indirectly measuring fault latency is presented.

ISBI Practice Guidelines for Burn Care.

PubMed

2016-08-01

Practice guidelines (PGs) are recommendations for diagnosis and treatment of diseases and injuries, and are designed to define optimal evaluation and management. The first PGs for burn care addressed the issues encountered in developed countries, lacking consideration for circumstances in resource-limited settings (RLS). Thus, the mission of the 2014-2016 committee established by the International Society for Burn Injury (ISBI) was to create PGs for burn care to improve the care of burn patients in both RLS and resource-abundant settings. An important component of this effort is to communicate a consensus opinion on recommendations for burn care for different aspects of burn management. An additional goal is to reduce costs by outlining effective and efficient recommendations for management of medical problems specific to burn care. These recommendations are supported by the best research evidence, as well as by expert opinion. Although our vision was the creation of clinical guidelines that could be applicable in RLS, the ISBI PGs for Burn Care have been written to address the needs of burn specialists everywhere in the world. Copyright © 2016. Published by Elsevier Ltd.

Size, time, and asynchrony matter: the species-area relationship for parasites of freshwater fishes.

PubMed

Zelmer, Derek A

2014-10-01

The tendency to attribute species-area relationships to "island biogeography" effectively bypasses the examination of specific mechanisms that act to structure parasite communities. Positive covariation between fish size and infrapopulation richness should not be examined within the typical extinction-based paradigm, but rather should be addressed from the standpoint of differences in colonization potential among individual hosts. Although most mechanisms producing the aforementioned pattern constitute some variation of passive sampling, the deterministic aspects of the accumulation of parasite individuals by fish hosts makes untenable the suggestion that infracommunities of freshwater fishes are stochastic assemblages. At the component community level, application of extinction-dependent mechanisms might be appropriate, given sufficient time for colonization, but these structuring forces likely act indirectly through their effects on the host community to increase the probability of parasite persistence. At all levels, the passive sampling hypothesis is a relevant null model. The tendency for mechanisms that produce species-area relationships to produce nested subset patterns means that for most systems, the passive sampling hypothesis can be addressed through the application of appropriate null models of nested subset structure.

Exploring the Masculine Identity in the Context of HIV Prevention in Chile.

PubMed

Ferrer, Lilian; Cianelli, Rosina; Villegas, Natalia; Reed, Reiley; Bernales, Margarita; Repetto, Paula; Hufstader, Theodore; Lara, Loreto; Irarrázabal, Lisette; Peragallo-Montano, Nilda

2016-03-01

This study aims to describe human immunodeficiency virus (HIV)-related knowledge and beliefs, as well as understanding attitudes towards masculinity in the context of HIV prevention, held among Chilean men. This study reports the qualitative findings of a sequential qualitative-quantitative mixed methodology study: Bringing men into HIV Prevention in Chile, NIH R01 TW007674-03. Twenty in-depth interviews using a qualitative, descriptive approach to elicit information for the study were conducted among men residing in two communities of low socio-economic status in Santiago, Chile. Content analysis of interviews revealed three main themes regarding machismo and how it relates to HIV: sexuality and machismo, the changing nature of machismo, and violence against women. Addressing HIV and intimate partner violence through developing education programs tailored to meet the needs of Chilean men are needed to include men in HIV prevention efforts. Specifically, incorporating ideas of what men consider healthy masculinity and working to destigmatize men who have sex with men are important steps in addressing the negative aspects of machismo. © 2016 Sigma Theta Tau International.

Building confidence and credibility amid growing model and computing complexity

NASA Astrophysics Data System (ADS)

Evans, K. J.; Mahajan, S.; Veneziani, C.; Kennedy, J. H.

2017-12-01

As global Earth system models are developed to answer an ever-wider range of science questions, software products that provide robust verification, validation, and evaluation must evolve in tandem. Measuring the degree to which these new models capture past behavior, predict the future, and provide the certainty of predictions is becoming ever more challenging for reasons that are generally well known, yet are still challenging to address. Two specific and divergent needs for analysis of the Accelerated Climate Model for Energy (ACME) model - but with a similar software philosophy - are presented to show how a model developer-based focus can address analysis needs during expansive model changes to provide greater fidelity and execute on multi-petascale computing facilities. A-PRIME is a python script-based quick-look overview of a fully-coupled global model configuration to determine quickly if it captures specific behavior before significant computer time and expense is invested. EVE is an ensemble-based software framework that focuses on verification of performance-based ACME model development, such as compiler or machine settings, to determine the equivalence of relevant climate statistics. The challenges and solutions for analysis of multi-petabyte output data are highlighted from the aspect of the scientist using the software, with the aim of fostering discussion and further input from the community about improving developer confidence and community credibility.

Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization

PubMed Central

Desoubeaux, Guillaume; Cray, Carolyn

2017-01-01

Invasive aspergillosis has been studied in laboratory by the means of plethora of distinct animal models. They were developed to address pathophysiology, therapy, diagnosis, or miscellaneous other concerns associated. However, there are great discrepancies regarding all the experimental variables of animal models, and a thorough focus on them is needed. This systematic review completed a comprehensive bibliographic analysis specifically-based on the technical features of rodent models infected with Aspergillus fumigatus. Out the 800 articles reviewed, it was shown that mice remained the preferred model (85.8% of the referenced reports), above rats (10.8%), and guinea pigs (3.8%). Three quarters of the models involved immunocompromised status, mainly by steroids (44.4%) and/or alkylating drugs (42.9%), but only 27.7% were reported to receive antibiotic prophylaxis to prevent from bacterial infection. Injection of spores (30.0%) and inhalation/deposition into respiratory airways (66.9%) were the most used routes for experimental inoculation. Overall, more than 230 distinct A. fumigatus strains were used in models. Of all the published studies, 18.4% did not mention usage of any diagnostic tool, like histopathology or mycological culture, to control correct implementation of the disease and to measure outcome. In light of these findings, a consensus discussion should be engaged to establish a minimum standardization, although this may not be consistently suitable for addressing all the specific aspects of invasive aspergillosis. PMID:28559881

AMEG: the new SETAC advisory group on aquatic macrophyte ecotoxicology

PubMed Central

Davies, Jo; Dobbs, Michael; Ebke, Peter; Hanson, Mark; Hommen, Udo; Knauer, Katja; Loutseti, Stefania; Maltby, Lorraine; Mohr, Silvia; Poovey, Angela; Poulsen, Véronique

2010-01-01

Introduction and background Primary producers play critical structural and functional roles in aquatic ecosystems; therefore, it is imperative that the potential risks of toxicants to aquatic plants are adequately assessed in the risk assessment of chemicals. The standard required macrophyte test species is the floating (non-sediment-rooted) duckweed Lemna spp. This macrophyte species might not be representative of all floating, rooted, emergent, and submerged macrophyte species because of differences in the duration and mode of exposure; sensitivity to the specific toxic mode of action of the chemical; and species-specific traits (e.g., duckweed's very short generation time). Discussion and perspectives These topics were addressed during the workshop entitled “Aquatic Macrophyte Risk Assessment for Pesticides” (AMRAP) where a risk assessment scheme for aquatic macrophytes was proposed. Four working groups evolved from this workshop and were charged with the task of developing Tier 1 and higher-tier aquatic macrophyte risk assessment procedures. Subsequently, a SETAC Advisory Group, the Macrophyte Ecotoxicology Group (AMEG) was formed as an umbrella organization for various macrophyte working groups. The purpose of AMEG is to provide scientifically based guidance in all aspects of aquatic macrophyte testing in the laboratory and field, including prospective as well as retrospective risk assessments for chemicals. As AMEG expands, it will begin to address new topics including bioremediation and sustainable management of aquatic macrophytes in the context of ecosystem services. PMID:20191396

AMEG: the new SETAC advisory group on aquatic macrophyte ecotoxicology.

PubMed

Arts, Gertie; Davies, Jo; Dobbs, Michael; Ebke, Peter; Hanson, Mark; Hommen, Udo; Knauer, Katja; Loutseti, Stefania; Maltby, Lorraine; Mohr, Silvia; Poovey, Angela; Poulsen, Véronique

2010-05-01

Primary producers play critical structural and functional roles in aquatic ecosystems; therefore, it is imperative that the potential risks of toxicants to aquatic plants are adequately assessed in the risk assessment of chemicals. The standard required macrophyte test species is the floating (non-sediment-rooted) duckweed Lemna spp. This macrophyte species might not be representative of all floating, rooted, emergent, and submerged macrophyte species because of differences in the duration and mode of exposure; sensitivity to the specific toxic mode of action of the chemical; and species-specific traits (e.g., duckweed's very short generation time). These topics were addressed during the workshop entitled "Aquatic Macrophyte Risk Assessment for Pesticides" (AMRAP) where a risk assessment scheme for aquatic macrophytes was proposed. Four working groups evolved from this workshop and were charged with the task of developing Tier 1 and higher-tier aquatic macrophyte risk assessment procedures. Subsequently, a SETAC Advisory Group, the Macrophyte Ecotoxicology Group (AMEG) was formed as an umbrella organization for various macrophyte working groups. The purpose of AMEG is to provide scientifically based guidance in all aspects of aquatic macrophyte testing in the laboratory and field, including prospective as well as retrospective risk assessments for chemicals. As AMEG expands, it will begin to address new topics including bioremediation and sustainable management of aquatic macrophytes in the context of ecosystem services.

A positive deviance perspective on hospital knowledge management: analysis of Baldrige Award recipients 2002-2008.

PubMed

Griffith, John R; Fear, Kathleen M; Lammers, Eric; Banaszak-Holl, Jane; Lemak, Christy Harris; Zheng, Kai

2013-01-01

Knowledge management (KM) is emerging as an important aspect of achieving excellent organizational performance, but its use has not been widely explored for hospitals. Taking a positive deviance perspective, we analyzed the applications of nine healthcare organizations (HCOs) that received the Malcolm Baldrige National Quality Award from 2002 to 2008. Baldrige Award applications constitute a uniquely comprehensive, standardized, and audited record of HCOs achieving near-benchmark performance. Applications are organized around leadership, strategy, customers, information, workforce, and operations. We find that KM is frequently referenced in all sections, and about two thirds of each application addresses KM-related issues. Many specific KM activities, such as strategic and action plans, communications, and processes to capture internal and external knowledge, are addressed by all nine applications. We present examples illustrating these frequently appearing KM concepts. Baldrige Award-recipient HCOs apply continuous improvement to KM processes, as they do to their organizations as a whole. We conclude that these HCOs have developed sophisticated, comprehensive KM processes to align both culture and specific procedures throughout the organization. KM in these organizations is a deliberate effort to keep all relevant knowledge at the fingertips of every worker, characterized by frequent communication, careful maintenance of content accuracy, and redundant distribution. We also conclude that the extent and rigor of their KM practice distinguish them from other U.S. hospitals.

Identifying Basic Factors for Communal Prosperity - Space Technologies are Bridging this Gap

NASA Technical Reports Server (NTRS)

Habib, Shahid

2006-01-01

There are many aspects, which are important for maintaining environmentally clean and safe conditions for a healthy and economically self-sufficient community. This problem was somewhat of a lesser concern in earlier days because many communities were small, isolated and solely dependent upon their owners or landlords. Due to an astronomical growth in human population within the last century, extensive use of combustion technologies, and changing environmental conditions has resulted in scarcity of natural resources. In reality, the societal sustainability issues are becoming much more acute and complex. Therefore, the researchers and social scientists are joining forces to address these topics and find solutions to many contentious areas such as public health and diseases, water resources, agriculture production, survivability during and after the natural disasters, energy needs and many others. Forthrightly speaking, there is no canned solution or a methodology to go about solving these issues since the magnitude and complexity of these issues are multi-dimensional and are further inter-locked with other areas. A common sense tells us that we need data, resources and technologies to begin addressing these problems. This is where space observations have provided us with tremendous information and opportunities, which are of great assets to the science, economist, and social scientists. This paper specifically addresses what are critical areas for a successful societal sustainability and growth; and how can we take advantage of multiple sensors and models already in existence. Increasing our knowledge of the home planet, via amplified set of observations, is certainly a right step in a right direction. Furthermore, this is a pre-requisite in understanding multiple hazard phenomena's. This paper further examines various space sensors and observing architectures that can be useful specifically in addressing some of these complex issues. The ultimate goal is to serve the society by providing such valuable information so the decision makers can take full advantage in making timely societal decisions.

DNA Methylation Adjusts the Specificity of Memories Depending on the Learning Context and Promotes Relearning in Honeybees

PubMed Central

Biergans, Stephanie D.; Claudianos, Charles; Reinhard, Judith; Galizia, C. G.

2016-01-01

The activity of the epigenetic writers DNA methyltransferases (Dnmts) after olfactory reward conditioning is important for both stimulus-specific long-term memory (LTM) formation and extinction. It, however, remains unknown which components of memory formation Dnmts regulate (e.g., associative vs. non-associative) and in what context (e.g., varying training conditions). Here, we address these aspects in order to clarify the role of Dnmt-mediated DNA methylation in memory formation. We used a pharmacological Dnmt inhibitor and classical appetitive conditioning in the honeybee Apis mellifera, a well characterized model for classical conditioning. We quantified the effect of DNA methylation on naïve odor and sugar responses, and on responses following olfactory reward conditioning. We show that (1) Dnmts do not influence naïve odor or sugar responses, (2) Dnmts do not affect the learning of new stimuli, but (3) Dnmts influence odor-coding, i.e., ‘correct’ (stimulus-specific) LTM formation. Particularly, Dnmts reduce memory specificity when experience is low (one-trial training), and increase memory specificity when experience is high (multiple-trial training), generating an ecologically more useful response to learning. (4) In reversal learning conditions, Dnmts are involved in regulating both excitatory (re-acquisition) and inhibitory (forgetting) processes. PMID:27672359

DNA Methylation Adjusts the Specificity of Memories Depending on the Learning Context and Promotes Relearning in Honeybees.

PubMed

Biergans, Stephanie D; Claudianos, Charles; Reinhard, Judith; Galizia, C G

2016-01-01

The activity of the epigenetic writers DNA methyltransferases (Dnmts) after olfactory reward conditioning is important for both stimulus-specific long-term memory (LTM) formation and extinction. It, however, remains unknown which components of memory formation Dnmts regulate (e.g., associative vs. non-associative) and in what context (e.g., varying training conditions). Here, we address these aspects in order to clarify the role of Dnmt-mediated DNA methylation in memory formation. We used a pharmacological Dnmt inhibitor and classical appetitive conditioning in the honeybee Apis mellifera, a well characterized model for classical conditioning. We quantified the effect of DNA methylation on naïve odor and sugar responses, and on responses following olfactory reward conditioning. We show that (1) Dnmts do not influence naïve odor or sugar responses, (2) Dnmts do not affect the learning of new stimuli, but (3) Dnmts influence odor-coding, i.e., 'correct' (stimulus-specific) LTM formation. Particularly, Dnmts reduce memory specificity when experience is low (one-trial training), and increase memory specificity when experience is high (multiple-trial training), generating an ecologically more useful response to learning. (4) In reversal learning conditions, Dnmts are involved in regulating both excitatory (re-acquisition) and inhibitory (forgetting) processes.

"It goes against the grain": A qualitative study of the experiences of parents' administering distressing health-care procedures for their child at home.

PubMed

Spiers, Gemma; Beresford, Bryony

2017-10-01

Parents caring for children with complex and long-term conditions at home take on responsibility for technical health-care procedures that may cause their child distress. Little evidence exists about parents' experience of this specific aspect of their caring role. To explore and understand parents' experiences of administering distressing health-care procedures as part of caring for their child at home. An explorative qualitative study. A purposive sample of parents who were currently carrying out, or had previously carried out, health-care procedures they thought their child found distressing was recruited. Data were collected using in-depth interviews and analysed thematically. Administering these procedures was not just a clinical task. That the procedures caused distress for the child meant there were additional issues to consider and address. A major issue for parents was being able to prevent or minimize their child's distress, which in turn was closely linked to parents' own emotional discomfort in the situation. Parents also had to manage their child's physical and verbal resistance, their own emotional discomfort during the procedure, and the presence and reaction of siblings in the home. The types of support that were valued by parents included advice about managing their child's distress and resistance, occasional assistance with procedures, addressing the emotional aspects of the role, and adequate training and on-going supervision. The "added" challenges of assuming this responsibility have implications for the support of parents caring for ill children at home. © 2017 The Authors Health Expectations Published by John Wiley & Sons Ltd.

A New Socio-technical Model for Studying Health Information Technology in Complex Adaptive Healthcare Systems

PubMed Central

Sittig, Dean F.; Singh, Hardeep

2011-01-01

Conceptual models have been developed to address challenges inherent in studying health information technology (HIT). This manuscript introduces an 8-dimensional model specifically designed to address the socio-technical challenges involved in design, development, implementation, use, and evaluation of HIT within complex adaptive healthcare systems. The 8 dimensions are not independent, sequential, or hierarchical, but rather are interdependent and interrelated concepts similar to compositions of other complex adaptive systems. Hardware and software computing infrastructure refers to equipment and software used to power, support, and operate clinical applications and devices. Clinical content refers to textual or numeric data and images that constitute the “language” of clinical applications. The human computer interface includes all aspects of the computer that users can see, touch, or hear as they interact with it. People refers to everyone who interacts in some way with the system, from developer to end-user, including potential patient-users. Workflow and communication are the processes or steps involved in assuring that patient care tasks are carried out effectively. Two additional dimensions of the model are internal organizational features (e.g., policies, procedures, and culture) and external rules and regulations, both of which may facilitate or constrain many aspects of the preceding dimensions. The final dimension is measurement and monitoring, which refers to the process of measuring and evaluating both intended and unintended consequences of HIT implementation and use. We illustrate how our model has been successfully applied in real-world complex adaptive settings to understand and improve HIT applications at various stages of development and implementation. PMID:20959322

A new sociotechnical model for studying health information technology in complex adaptive healthcare systems.

PubMed

Sittig, Dean F; Singh, Hardeep

2010-10-01

Conceptual models have been developed to address challenges inherent in studying health information technology (HIT). This manuscript introduces an eight-dimensional model specifically designed to address the sociotechnical challenges involved in design, development, implementation, use and evaluation of HIT within complex adaptive healthcare systems. The eight dimensions are not independent, sequential or hierarchical, but rather are interdependent and inter-related concepts similar to compositions of other complex adaptive systems. Hardware and software computing infrastructure refers to equipment and software used to power, support and operate clinical applications and devices. Clinical content refers to textual or numeric data and images that constitute the 'language' of clinical applications. The human--computer interface includes all aspects of the computer that users can see, touch or hear as they interact with it. People refers to everyone who interacts in some way with the system, from developer to end user, including potential patient-users. Workflow and communication are the processes or steps involved in ensuring that patient care tasks are carried out effectively. Two additional dimensions of the model are internal organisational features (eg, policies, procedures and culture) and external rules and regulations, both of which may facilitate or constrain many aspects of the preceding dimensions. The final dimension is measurement and monitoring, which refers to the process of measuring and evaluating both intended and unintended consequences of HIT implementation and use. We illustrate how our model has been successfully applied in real-world complex adaptive settings to understand and improve HIT applications at various stages of development and implementation.

Teachers' reported practices for teaching writing in England.

PubMed

Dockrell, Julie E; Marshall, Chloë R; Wyse, Dominic

To date there have been no systematic studies examining the ways in which teachers in England focus and adapt their teaching of writing. The current study addresses this gap by investigating the nature and frequency of teachers' approaches to the teaching of writing in a sample of English primary schools, using the 'simple view of writing' as a framework to examine the extent to which different aspects of the writing process are addressed. One hundred and eighty-eight staff from ten different schools responded to an online questionnaire. Only the data from class teachers (n = 88) who responded to all items on the questionnaire were included in the final analyses. Respondents enjoyed teaching writing and felt prepared to teach it. However, despite feeling that they were effective in identifying approaches to support students' writing, nearly half reported that supporting struggling writers was problematic for them. Overall teachers reported more work at word level, occurring several times a week, than with transcription, sentence or text levels, which were reported to occur weekly. Planning, reviewing and revising occurred least often, only monthly. For these variables no differences were found between teachers of younger (age 4-7) and older students (age 8-11). By contrast, an examination of specific aspects of each component revealed differences between the teachers of the two age groups. Teachers of younger students focused more frequently on phonic activities related to spelling, whereas teachers of older students focussed more on word roots, punctuation, word classes and the grammatical function of words, sentence-level work, and paragraph construction.

College Campus Community Readiness to Address Intimate Partner Violence Among LGBTQ+ Young Adults: A Conceptual and Empirical Examination.

PubMed

Edwards, Katie M; Littleton, Heather L; Sylaska, Kateryna M; Crossman, Annie L; Craig, Meghan

2016-09-01

This paper provides an overview of a conceptual model that integrates theories of social ecology, minority stress, and community readiness to better understand risk for and outcomes of intimate partner violence (IPV) among LGBTQ+ college students. Additionally, online survey data was collected from a sample of 202 LGBTQ+ students enrolled in 119 colleges across the United States to provide preliminary data on some aspects of the proposed model. Results suggested that students generally thought their campuses were low in readiness to address IPV; that is, students felt that their campuses could do more to address IPV and provide IPV services specific to LGBTQ+ college students. Perceptions of greater campus readiness to address IPV among LGBTQ+ college students was significantly and positively related to a more favorable LGBTQ+ campus climate and a greater sense of campus community. Additionally, IPV victims were more likely to perceive higher levels of campus community readiness than non-IPV victims. There was no association between IPV perpetration and perceptions of campus community readiness. Greater sense of community was marginally and inversely related to IPV victimization and perpetration. Sense of community and LGBTQ+ campus climate also varied to some extent as a function of region of the country and type of institution. Implications for further development and refinement of the conceptual model, as well as future research applying this model to better understand IPV among sexual minority students are discussed. © Society for Community Research and Action 2016.

Health Aspects of Climate Change in Cities with Mediterranean Climate, and Local Adaptation Plans

PubMed Central

Paz, Shlomit; Negev, Maya; Clermont, Alexandra; Green, Manfred S.

2016-01-01

Cities with a Mediterranean-type climate (Med-cities) are particularly susceptible to health risks from climate change since they are located in biogeographical hot-spots that experience some of the strongest effects of the changing climate. The study aims to highlight health impacts of climate change in Med-cities, analyze local climate adaptation plans and make adaptation policy recommendations for the Med-city level. We identified five Med-cities with a climate change adaptation plan: Adelaide, Barcelona, Cape Town, Los Angeles and Santiago. Beyond their similar Med-climate features (although Santiago’s are slightly different), the cities have different socio-economic characteristics in various aspects. We analyzed each plan according to how it addresses climate change-related drivers of health impacts among city dwellers. For each driver, we identified the types of policy adaptation tools that address it in the urban climate adaptation plans. The surveyed cities address most of the fundamental climate change-related drivers of risks to human health, including rising temperatures, flooding and drought, but the policy measures to reduce negative impacts vary across cities. We suggest recommendations for Med-cities in various aspects, depending on their local needs and vulnerability challenges: assessment of health risks, extreme events management and long-term adaptation, among others. PMID:27110801

Health Aspects of Climate Change in Cities with Mediterranean Climate, and Local Adaptation Plans.

PubMed

Paz, Shlomit; Negev, Maya; Clermont, Alexandra; Green, Manfred S

2016-04-21

Cities with a Mediterranean-type climate (Med-cities) are particularly susceptible to health risks from climate change since they are located in biogeographical hot-spots that experience some of the strongest effects of the changing climate. The study aims to highlight health impacts of climate change in Med-cities, analyze local climate adaptation plans and make adaptation policy recommendations for the Med-city level. We identified five Med-cities with a climate change adaptation plan: Adelaide, Barcelona, Cape Town, Los Angeles and Santiago. Beyond their similar Med-climate features (although Santiago's are slightly different), the cities have different socio-economic characteristics in various aspects. We analyzed each plan according to how it addresses climate change-related drivers of health impacts among city dwellers. For each driver, we identified the types of policy adaptation tools that address it in the urban climate adaptation plans. The surveyed cities address most of the fundamental climate change-related drivers of risks to human health, including rising temperatures, flooding and drought, but the policy measures to reduce negative impacts vary across cities. We suggest recommendations for Med-cities in various aspects, depending on their local needs and vulnerability challenges: assessment of health risks, extreme events management and long-term adaptation, among others.

Physical fitness and job performance of firefighters.

PubMed

Rhea, Matthew R; Alvar, Brent A; Gray, Rayne

2004-05-01

Accurate correlations between a wide range of physical fitness measures and occupational demands are needed in order to identify specific fitness tests and training needs for firefighters. Twenty professional firefighters performed numerous fitness and job-related performance tests. Pearson product moment correlations were performed to identify the relationship between fitness components and job performance. Significant correlations (p <0.05) with job performance were identified for total fitness (r = -0.62), bench press strength (r = -0.66), hand grip strength (r = -0.71), bent-over row endurance (r = -0.61), bench press endurance (r = -0.73), shoulder press endurance (r = -0.71), bicep endurance (r = -0.69), squat endurance (r = -0.47), and 400-m sprint time (r = 0.79). It is apparent that firefighting taxes virtually all aspects of physical fitness. These data can help the exercise specialist choose appropriate tests and prescribe specific fitness programs for firefighters. Traditional firefighter exercise programs focusing mainly on cardiovascular fitness should be replaced with physical conditioning programs that address all components of fitness.

A GIS approach to conducting biogeochemical research in wetlands

NASA Technical Reports Server (NTRS)

Brannon, David P.; Irish, Gary J.

1985-01-01

A project was initiated to develop an environmental data base to address spatial aspects of both biogeochemical cycling and resource management in wetlands. Specific goals are to make regional methane flux estimates and site specific water level predictions based on man controlled water releases within a wetland study area. The project will contribute to the understanding of the Earth's biosphere through its examination of the spatial variability of methane emissions. Although wetlands are thought to be one of the primary sources for release of methane to the atmosphere, little is known about the spatial variability of methane flux. Only through a spatial analysis of methane flux rates and the environmental factors which influence such rates can reliable regional and global methane emissions be calculated. Data will be correlated and studied from Landsat 4 instruments, from a ground survey of water level recorders, precipitation recorders, evaporation pans, and supplemental gauges, and from flood gate water release; and regional methane flux estimates will be made.

Neurophysiological measures of involuntary and voluntary attention allocation and dispositional differences in need for cognition.

PubMed

Enge, Sören; Fleischhauer, Monika; Brocke, Burkhard; Strobel, Alexander

2008-06-01

Need for cognition (NFC) refers to stable individual differences in the intrinsic motivation to engage in and enjoy effortful cognitive endeavors and has been a useful predictor of dispositional differences in information processing. Although cognitive resource allocation conceptualized as cognitive effort is assumed to be the key mediator of NFC-specific processing, to date no research has systematically addressed its underpinnings. Using a neurocognitive paradigm and recording event-related potentials associated with bottom-up and top-down-driven aspects of attention, the present research contributes to filling this gap. In Study 1, high-NFC individuals showed larger P3a amplitudes to contextually novel events, indicating greater involuntary (automatic) attention allocation. This effect was replicated in Study 2, where NFC also was positively correlated with the P3b to target stimuli, indicating voluntary (controlled) processes of attention allocation. Thus, our findings provide first evidence for neurophysiological correlates of NFC and can improve the understanding of NFC-specific processing.

Power technologies and the space future

NASA Technical Reports Server (NTRS)

Faymon, Karl A.; Fordyce, J. Stuart; Brandhorst, Henry W., Jr.

1991-01-01

Advancements in space power and energy technologies are critical to serve space development needs and help solve problems on Earth. The availability of low cost power and energy in space will be the hallmark of this advance. Space power will undergo a dramatic change for future space missions. The power systems which have served the U.S. space program so well in the past will not suffice for the missions of the future. This is especially true if the space commercialization is to become a reality. New technologies, and new and different space power architectures and topologies will replace the lower power, low-voltage systems of the past. Efficiencies will be markedly improved, specific powers will be greatly increased, and system lifetimes will be markedly extended. Space power technology is discussed - its past, its current status, and predictions about where it will go in the future. A key problem for power and energy is its cost of affordability. Power must be affordable or it will not serve future needs adequately. This aspect is also specifically addressed.

Sociodemographic Predictors of Sex Offender Stigma: How Politics Impact Attitudes, Social Distance, and Perceptions of Sex Offender Recidivism.

PubMed

DeLuca, Joseph S; Vaccaro, John; Rudnik, Amalia; Graham, Nicole; Giannicchi, Anna; Yanos, Philip T

2017-08-01

Stigma toward general criminal offenders has been found to be particularly salient among community members who identify as politically conservative; however, less is known about how political identification relates to stigma toward sex offenders. This is a particularly important area of inquiry, given that criminal jurisprudence and politics legitimatize stigmatizing labels attributed to sex offenders through laws and policies that apply specifically to this group. A nonrandom sample ( N = 518) of participants living in the United States was recruited for this survey study. Findings indicated that a specific aspect of conservative political ideology-right-wing authoritarianism (RWA)-significantly predicts negative attitudes and intended social distancing behavior toward sex offenders, even when controlling for other important predictors, such as education and prior contact. RWA was found to be the strongest predictor of negative attitudes and estimations of sex offender recidivism, and also significantly predicted intended social distancing behavior. Implications for addressing stigma toward sex offenders are discussed.

Y chromosome STR typing in crime casework.

PubMed

Roewer, Lutz

2009-01-01

Since the beginning of the nineties the field of forensic Y chromosome analysis has been successfully developed to become commonplace in laboratories working in crime casework all over the world. The ability to identify male-specific DNA renders highly variable Y-chromosomal polymorphisms, the STR sequences, an invaluable addition to the standard panel of autosomal loci used in forensic genetics. The male-specificity makes the Y chromosome especially useful in cases of male/female cell admixture, namely in sexual assault cases. On the other hand, the haploidy and patrilineal inheritance complicates the interpretation of a Y-STR match, because male relatives share for several generations an identical Y-STR profile. Since paternal relatives tend to live in the geographic and cultural territory of their ancestors, the Y chromosome analysis has a potential to make inferences on the population of origin of a given DNA profile. This review addresses the fields of application of Y chromosome haplotyping, the interpretation of results, databasing efforts and population genetics aspects.

Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions

PubMed Central

Muller, Martha; Obert, Caroline; Burnham, Corinna; Mann, Beth; Li, Yimei; Hayden, Randall T; Pestina, Tamara; Persons, Derek; Camilli, Andrew

2014-01-01

Summary Sickle cell disease (SCD) patients are at high risk of contracting pneumococcal infection. To address this risk, they receive pneumococcal vaccines, and antibiotic prophylaxis and treatment. To assess the impact of SCD and these interventions on pneumococcal genetic architecture, we examined the genomes of over 300 pneumococcal isolates from SCD patients over 20 years. Modern SCD strains retained invasive capacity but shifted away from the serotypes used in vaccines. These strains had specific genetic changes related to antibiotic resistance, capsule biosynthesis, metabolism and metal transport. A murine SCD model coupled with Tn-seq mutagenesis identified 60 non-capsular pneumococcal genes under differential selective pressure in SCD, which correlated with aspects of SCD pathophysiology. Further, virulence determinants in the SCD context were distinct from the general population and protective capacity of potential antigens was lost over time in SCD. This highlights the importance of understanding bacterial pathogenesis in the context of high-risk individuals. PMID:24832453

A web based health technology assessment in tele-echocardiography: the experience within an Italian project.

PubMed

Giansanti, Daniele; Morelli, Sandra; Maccioni, Giovanni; Guerriero, Lorenzo; Bedini, Remo; Pepe, Gennaro; Colombo, Cesare; Borghi, Gabriella; Macellari, Velio

2009-01-01

Due to major advances in the information technology, telemedicine applications are ready for a widespread use. Nonetheless, to allow their diffusion in National Health Care Systems (NHCSs) specific methodologies of health technology assessment (HTA) should be used to assess the standardization, the overall quality, the interoperability, the addressing to legal, economic and cost benefit aspects. One of the limits to the diffusion of the digital tele-echocardiography (T-E) applications in the NHCS lacking of a specific methodology for the HTA. In the present study, a solution offering a structured HTA of T-E products was designed. The methodology assured also the definition of standardized quality levels for the application. The first level represents the minimum level of acceptance; the other levels are accessory levels useful for a more accurate assessment of the product. The methodology showed to be useful to rationalize the process of standardization and has received a high degree of acceptance by the subjects involved in the study.

Beyond Fluorescent Proteins: Hybrid and Bioluminescent Indicators for Imaging Neural Activities.

PubMed

Wang, Anqi; Feng, Jiesi; Li, Yulong; Zou, Peng

2018-04-18

Optical biosensors have been invaluable tools in neuroscience research, as they provide the ability to directly visualize neural activity in real time, with high specificity, and with exceptional spatial and temporal resolution. Notably, a majority of these sensors are based on fluorescent protein scaffolds, which offer the ability to target specific cell types or even subcellular compartments. However, fluorescent proteins are intrinsically bulky tags, often insensitive to the environment, and always require excitation light illumination. To address these limitations, there has been a proliferation of alternative sensor scaffolds developed in recent years, including hybrid sensors that combine the advantages of synthetic fluorophores and genetically encoded protein tags, as well as bioluminescent probes. While still in their early stage of development as compared with fluorescent protein-based sensors, these novel probes have offered complementary solutions to interrogate various aspects of neuronal communication, including transmitter release, changes in membrane potential, and the production of second messengers. In this Review, we discuss these important new developments with a particular focus on design strategies.

Reverse transcription-polymerase chain reaction molecular testing of cytology specimens: Pre-analytic and analytic factors.

PubMed

Bridge, Julia A

2017-01-01

The introduction of molecular testing into cytopathology laboratory practice has expanded the types of samples considered feasible for identifying genetic alterations that play an essential role in cancer diagnosis and treatment. Reverse transcription-polymerase chain reaction (RT-PCR), a sensitive and specific technical approach for amplifying a defined segment of RNA after it has been reverse-transcribed into its DNA complement, is commonly used in clinical practice for the identification of recurrent or tumor-specific fusion gene events. Real-time RT-PCR (quantitative RT-PCR), a technical variation, also permits the quantitation of products generated during each cycle of the polymerase chain reaction process. This review addresses qualitative and quantitative pre-analytic and analytic considerations of RT-PCR as they relate to various cytologic specimens. An understanding of these aspects of genetic testing is central to attaining optimal results in the face of the challenges that cytology specimens may present. Cancer Cytopathol 2017;125:11-19. © 2016 American Cancer Society. © 2016 American Cancer Society.

A qualitative review of existing national and international occupational safety and health policies relating to occupational sedentary behaviour.

PubMed

Coenen, Pieter; Gilson, Nicholas; Healy, Genevieve N; Dunstan, David W; Straker, Leon M

2017-04-01

Prolonged sedentary time is now recognised as an emergent ergonomics issue. We aimed to review current occupational safety and health policies relevant to occupational sedentary behaviour. An electronic search for documents was conducted on websites of ergonomics and occupational safety and health organisations from 10 countries and six international/pan-European agencies. Additionally, 43 informants (nine countries) were contacted and an international conference workshop held. 119 documents (e.g. legislation, guidelines, codes of practice) were identified. Using a qualitative synthesis, it was observed that many jurisdictions had legal frameworks establishing a duty of care for employers, designers/manufacturers/suppliers and employees. While no occupational authority policies focusing specifically on sedentary behaviour were found, relevant aspects of existing policies were identified. We highlight implications for ergonomics research and practice and recommend the development of policy to specifically address occupational sedentary behaviour and support workplace initiatives to assess and control the risks of this emergent hazard. Copyright © 2016 Elsevier Ltd. All rights reserved.

Epistemic Uncertainty: Turkish Children with Specific Language Impairment and Their Comprehension of Tense and Aspect

ERIC Educational Resources Information Center

Yarbay Duman, Tuba; Topbas, Seyhun

2016-01-01

Background: Impairments in tense morphology are characteristic of English-speaking children with specific language impairment (SLI). Recent studies have investigated the role that aspect plays in the difficulties found in tense morphology. It has been suggested that children with SLI are less sensitive to aspect and its interaction with tense than…

Climate-Driven Reshuffling of Species and Genes: Potential Conservation Roles for Species Translocations and Recombinant Hybrid Genotypes

PubMed Central

Scriber, Jon Mark

2013-01-01

Comprising 50%–75% of the world’s fauna, insects are a prominent part of biodiversity in communities and ecosystems globally. Biodiversity across all levels of biological classifications is fundamentally based on genetic diversity. However, the integration of genomics and phylogenetics into conservation management may not be as rapid as climate change. The genetics of hybrid introgression as a source of novel variation for ecological divergence and evolutionary speciation (and resilience) may generate adaptive potential and diversity fast enough to respond to locally-altered environmental conditions. Major plant and herbivore hybrid zones with associated communities deserve conservation consideration. This review addresses functional genetics across multi-trophic-level interactions including “invasive species” in various ecosystems as they may become disrupted in different ways by rapid climate change. “Invasive genes” (into new species and populations) need to be recognized for their positive creative potential and addressed in conservation programs. “Genetic rescue” via hybrid translocations may provide needed adaptive flexibility for rapid adaptation to environmental change. While concerns persist for some conservationists, this review emphasizes the positive aspects of hybrids and hybridization. Specific implications of natural genetic introgression are addressed with a few examples from butterflies, including transgressive phenotypes and climate-driven homoploid recombinant hybrid speciation. Some specific examples illustrate these points using the swallowtail butterflies (Papilionidae) with their long-term historical data base (phylogeographical diversity changes) and recent (3-decade) climate-driven temporal and genetic divergence in recombinant homoploid hybrids and relatively recent hybrid speciation of Papilio appalachiensis in North America. Climate-induced “reshuffling” (recombinations) of species composition, genotypes, and genomes may become increasingly ecologically and evolutionarily predictable, but future conservation management programs are more likely to remain constrained by human behavior than by lack of academic knowledge. PMID:26462579

Spiritually Integrated Cognitive Processing Therapy: A New Treatment for Post-traumatic Stress Disorder That Targets Moral Injury.

PubMed

Pearce, Michelle; Haynes, Kerry; Rivera, Natalia R; Koenig, Harold G

2018-01-01

Post-traumatic stress disorder (PTSD) is a debilitating disorder, and current treatments leave the majority of patients with unresolved symptoms. Moral injury (MI) may be one of the barriers that interfere with recovery from PTSD, particularly among current or former military service members. Given the psychological and spiritual aspects of MI, an intervention that addresses MI using spiritual resources in addition to psychological resources may be particularly effective in treating PTSD. To date, there are no existing empirically based individual treatments for PTSD and MI that make explicit use of a patient's spiritual resources, despite the evidence that spiritual beliefs/activities predict faster recovery from PTSD. To address this gap, we adapted Cognitive Processing Therapy (CPT), an empirically validated treatment for PTSD, to integrate clients' spiritual beliefs, practices, values, and motivations. We call this treatment Spiritually Integrated CPT (SICPT). This article describes this novel manualized therapeutic approach for treating MI in the setting of PTSD for spiritual/religious clients. We provide a description of SICPT and a brief summary of the 12 sessions. Then, we describe a case study in which the therapist helps a client use his spiritual resources to resolve MI and assist in the recovery from PTSD. SICPT may be a helpful way to reduce PTSD by targeting MI, addressing spiritual distress, and using a client's spiritual resources. In addition to the spiritual version (applicable for those of any religion and those who do not identify as religious), we have also developed 5 religion-specific manuals (Christianity, Judaism, Islam, Buddhism, and Hinduism) for clients who desire a more religion-specific approach.

Climate-Driven Reshuffling of Species and Genes: Potential Conservation Roles for Species Translocations and Recombinant Hybrid Genotypes.

PubMed

Scriber, Jon Mark

2013-12-24

Comprising 50%-75% of the world's fauna, insects are a prominent part of biodiversity in communities and ecosystems globally. Biodiversity across all levels of biological classifications is fundamentally based on genetic diversity. However, the integration of genomics and phylogenetics into conservation management may not be as rapid as climate change. The genetics of hybrid introgression as a source of novel variation for ecological divergence and evolutionary speciation (and resilience) may generate adaptive potential and diversity fast enough to respond to locally-altered environmental conditions. Major plant and herbivore hybrid zones with associated communities deserve conservation consideration. This review addresses functional genetics across multi-trophic-level interactions including "invasive species" in various ecosystems as they may become disrupted in different ways by rapid climate change. "Invasive genes" (into new species and populations) need to be recognized for their positive creative potential and addressed in conservation programs. "Genetic rescue" via hybrid translocations may provide needed adaptive flexibility for rapid adaptation to environmental change. While concerns persist for some conservationists, this review emphasizes the positive aspects of hybrids and hybridization. Specific implications of natural genetic introgression are addressed with a few examples from butterflies, including transgressive phenotypes and climate-driven homoploid recombinant hybrid speciation. Some specific examples illustrate these points using the swallowtail butterflies (Papilionidae) with their long-term historical data base (phylogeographical diversity changes) and recent (3-decade) climate-driven temporal and genetic divergence in recombinant homoploid hybrids and relatively recent hybrid speciation of Papilio appalachiensis in North America. Climate-induced "reshuffling" (recombinations) of species composition, genotypes, and genomes may become increasingly ecologically and evolutionarily predictable, but future conservation management programs are more likely to remain constrained by human behavior than by lack of academic knowledge.

Spiritually Integrated Cognitive Processing Therapy: A New Treatment for Post-traumatic Stress Disorder That Targets Moral Injury

PubMed Central

Pearce, Michelle; Haynes, Kerry; Rivera, Natalia R; Koenig, Harold G.

2018-01-01

Background Post-traumatic stress disorder (PTSD) is a debilitating disorder, and current treatments leave the majority of patients with unresolved symptoms. Moral injury (MI) may be one of the barriers that interfere with recovery from PTSD, particularly among current or former military service members. Objective Given the psychological and spiritual aspects of MI, an intervention that addresses MI using spiritual resources in addition to psychological resources may be particularly effective in treating PTSD. To date, there are no existing empirically based individual treatments for PTSD and MI that make explicit use of a patient’s spiritual resources, despite the evidence that spiritual beliefs/activities predict faster recovery from PTSD. Method To address this gap, we adapted Cognitive Processing Therapy (CPT), an empirically validated treatment for PTSD, to integrate clients’ spiritual beliefs, practices, values, and motivations. We call this treatment Spiritually Integrated CPT (SICPT). Results This article describes this novel manualized therapeutic approach for treating MI in the setting of PTSD for spiritual/religious clients. We provide a description of SICPT and a brief summary of the 12 sessions. Then, we describe a case study in which the therapist helps a client use his spiritual resources to resolve MI and assist in the recovery from PTSD. Conclusion SICPT may be a helpful way to reduce PTSD by targeting MI, addressing spiritual distress, and using a client’s spiritual resources. In addition to the spiritual version (applicable for those of any religion and those who do not identify as religious), we have also developed 5 religion-specific manuals (Christianity, Judaism, Islam, Buddhism, and Hinduism) for clients who desire a more religion-specific approach. PMID:29497585

Ethnocultural Aspects of Suicide in Young People: A Systematic Literature Review Part 1--Rates and Methods of Youth Suicide

ERIC Educational Resources Information Center

Colucci, Erminia; Martin, Graham

2007-01-01

The study of ethnocultural aspects of suicidal behaviour is, at the moment, still a neglected area. The relatively few studies available are mainly on adults; young people usually are not examined separately. The authors reviewed 82 publications on youth suicide that have addressed, to different degrees, the ethnicity/culture of the population…

Approche pedagogique d'un classique du cinema quebecois: Mon Oncle Antoine (Instructional Approach to a Quebec Film Classic: My Uncle Antoine).

ERIC Educational Resources Information Center

Viswanathan, Jacqueline

1990-01-01

An approach that introduces a Quebec film into a college-level course for advanced students of French is described. The technique addresses three aspects of the film: organization; the significance of certain film-making processes; and cultural and social aspects of the film as they relate to Quebecoise culture. (MSE)

The Multiple Faces of Peer Review in Higher Education. Five Learning Scenarios Developed for Digital Business

ERIC Educational Resources Information Center

Herzog, Michael A.; Katzlinger, Elisabeth

2017-01-01

Peer review, as an e-assessment tool incorporates the human factor to treat complexity for rating and grading students. It could address the qualitative more than quantitative aspects with flexible human feedback that leads up to metacognitive knowledge aspects, which e-assessment usually is not able to achieve. Peer review is an internationally…

The Role of Interest in Students' Writing Fluency and the Quality of the Product.

ERIC Educational Resources Information Center

Lewis, Dorothy P.

A study was conducted to examine the effects of students' interests on their writing. A group of 571 high school seniors, fluent and nonfluent in writing, completed a questionnaire dealing with aspects of writing interest, such as subject, form, or voice. Tape recorded interviews addressing the same aspects were conducted with 11 fluent seniors…

Social aspects of automation: Some critical insights

NASA Astrophysics Data System (ADS)

Nouzil, Ibrahim; Raza, Ali; Pervaiz, Salman

2017-09-01

Sustainable development has been recognized globally as one of the major driving forces towards the current technological innovations. To achieve sustainable development and attain its associated goals, it is very important to properly address its concerns in different aspects of technological innovations. Several industrial sectors have enjoyed productivity and economic gains due to advent of automation technology. It is important to characterize sustainability for the automation technology. Sustainability is key factor that will determine the future of our neighbours in time and it must be tightly wrapped around the double-edged sword of technology. In this study, different impacts of automation have been addressed using the ‘Circles of Sustainability’ approach as a framework, covering economic, political, cultural and ecological aspects and their implications. A systematic literature review of automation technology from its inception is outlined and plotted against its many outcomes covering a broad spectrum. The study is more focused towards the social aspects of the automation technology. The study also reviews literature to analyse the employment deficiency as one end of the social impact spectrum. On the other end of the spectrum, benefits to society through technological advancements, such as the Internet of Things (IoT) coupled with automation are presented.

Canada's Compassionate Care Benefit: is it an adequate public health response to addressing the issue of caregiver burden in end-of-life care?

PubMed

Williams, Allison M; Eby, Jeanette A; Crooks, Valorie A; Stajduhar, Kelli; Giesbrecht, Melissa; Vuksan, Mirjana; Cohen, S Robin; Brazil, Kevin; Allan, Diane

2011-05-18

An increasingly significant public health issue in Canada, and elsewhere throughout the developed world, pertains to the provision of adequate palliative/end-of-life (P/EOL) care. Informal caregivers who take on the responsibility of providing P/EOL care often experience negative physical, mental, emotional, social and economic consequences. In this article, we specifically examine how Canada's Compassionate Care Benefit (CCB)--a contributory benefits social program aimed at informal P/EOL caregivers--operates as a public health response in sustaining informal caregivers providing P/EOL care, and whether or not it adequately addresses known aspects of caregiver burden that are addressed within the population health promotion (PHP) model. As part of a national evaluation of Canada's Compassionate Care Benefit, 57 telephone interviews were conducted with Canadian informal P/EOL caregivers in 5 different provinces, pertaining to the strengths and weaknesses of the CCB and the general caregiving experience. Interview data was coded with Nvivo software and emerging themes were identified by the research team, with such findings published elsewhere. The purpose of the present analysis was identified after comparing the findings to the literature specific to caregiver burden and public health, after which data was analyzed using the PHP model as a guiding framework. Informal caregivers spoke to several of the determinants of health outlined in the PHP model that are implicated in their burden experience: gender, income and social status, working conditions, health and social services, social support network, and personal health practises and coping strategies. They recognized the need for improving the CCB to better address these determinants. This study, from the perspective of family caregivers, demonstrates that the CCB is not living up to its full potential in sustaining informal P/EOL caregivers. Effort is required to transform the CCB so that it may fulfill the potential it holds for serving as one public health response to caregiver burden that forms part of a healthy public policy that addresses the determinants of this burden.

Canada's Compassionate Care Benefit: Is it an adequate public health response to addressing the issue of caregiver burden in end-of-life care?

PubMed Central

2011-01-01

Background An increasingly significant public health issue in Canada, and elsewhere throughout the developed world, pertains to the provision of adequate palliative/end-of-life (P/EOL) care. Informal caregivers who take on the responsibility of providing P/EOL care often experience negative physical, mental, emotional, social and economic consequences. In this article, we specifically examine how Canada's Compassionate Care Benefit (CCB) - a contributory benefits social program aimed at informal P/EOL caregivers - operates as a public health response in sustaining informal caregivers providing P/EOL care, and whether or not it adequately addresses known aspects of caregiver burden that are addressed within the population health promotion (PHP) model. Methods As part of a national evaluation of Canada's Compassionate Care Benefit, 57 telephone interviews were conducted with Canadian informal P/EOL caregivers in 5 different provinces, pertaining to the strengths and weaknesses of the CCB and the general caregiving experience. Interview data was coded with Nvivo software and emerging themes were identified by the research team, with such findings published elsewhere. The purpose of the present analysis was identified after comparing the findings to the literature specific to caregiver burden and public health, after which data was analyzed using the PHP model as a guiding framework. Results Informal caregivers spoke to several of the determinants of health outlined in the PHP model that are implicated in their burden experience: gender, income and social status, working conditions, health and social services, social support network, and personal health practises and coping strategies. They recognized the need for improving the CCB to better address these determinants. Conclusions This study, from the perspective of family caregivers, demonstrates that the CCB is not living up to its full potential in sustaining informal P/EOL caregivers. Effort is required to transform the CCB so that it may fulfill the potential it holds for serving as one public health response to caregiver burden that forms part of a healthy public policy that addresses the determinants of this burden. PMID:21592383

Civic Meanings: Understanding the Constellations of Democratic and Civic Beliefs of Educators

ERIC Educational Resources Information Center

Lowham, Elizabeth A.; Lowham, James R.

2015-01-01

There is little doubt of public school's role in the enculturation of youth into American democracy. There are several aspects about which little is known that should be addressed prior to seeking options to understand and address civic education for the 21st century: first, the desired civic knowledge, skills, and predispositions are not clearly…

Ethnic Differences in the Self-Esteem/Academic Achievement Relationship: A Meta-Analysis.

ERIC Educational Resources Information Center

Wickline, Virginia B.

Four aspects related to self-esteem and academic achievement were addressed in the review. The first goal was to address methodological considerations of self-esteem measurement. Support for some self-esteem measures, as well as caveats and directions for future research, were indicated. The second goal was to determine whether a relationship…

77 FR 27146 - Proposed Amendment of Class E Airspace; Scammon Bay, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-09

... Docket No. 12-AAL-2, at the beginning of your comments. You may also submit comments through the Internet... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA 2012-0121... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

Educational Story as a Tool for Addressing the Framework for Information Literacy for Higher Education

ERIC Educational Resources Information Center

Vossler, Joshua J.; Watts, John

2017-01-01

To integrate the Framework for Information Literacy for Higher Education into their professional practice, librarians are called upon to address both the cognitive and emotional aspects of their learners. The Framework does not provide prescriptive details for its own deployment, so it is up to individuals, departments, or entire libraries to…

Why simulation can be efficient: on the preconditions of efficient learning in complex technology based practices.

PubMed

Hofmann, Bjørn

2009-07-23

It is important to demonstrate learning outcomes of simulation in technology based practices, such as in advanced health care. Although many studies show skills improvement and self-reported change to practice, there are few studies demonstrating patient outcome and societal efficiency. The objective of the study is to investigate if and why simulation can be effective and efficient in a hi-tech health care setting. This is important in order to decide whether and how to design simulation scenarios and outcome studies. Core theoretical insights in Science and Technology Studies (STS) are applied to analyze the field of simulation in hi-tech health care education. In particular, a process-oriented framework where technology is characterized by its devices, methods and its organizational setting is applied. The analysis shows how advanced simulation can address core characteristics of technology beyond the knowledge of technology's functions. Simulation's ability to address skilful device handling as well as purposive aspects of technology provides a potential for effective and efficient learning. However, as technology is also constituted by organizational aspects, such as technology status, disease status, and resource constraints, the success of simulation depends on whether these aspects can be integrated in the simulation setting as well. This represents a challenge for future development of simulation and for demonstrating its effectiveness and efficiency. Assessing the outcome of simulation in education in hi-tech health care settings is worthwhile if core characteristics of medical technology are addressed. This challenges the traditional technical versus non-technical divide in simulation, as organizational aspects appear to be part of technology's core characteristics.

Tests for the Assessment of Sport-Specific Performance in Olympic Combat Sports: A Systematic Review With Practical Recommendations.

PubMed

Chaabene, Helmi; Negra, Yassine; Bouguezzi, Raja; Capranica, Laura; Franchini, Emerson; Prieske, Olaf; Hbacha, Hamdi; Granacher, Urs

2018-01-01

The regular monitoring of physical fitness and sport-specific performance is important in elite sports to increase the likelihood of success in competition. This study aimed to systematically review and to critically appraise the methodological quality, validation data, and feasibility of the sport-specific performance assessment in Olympic combat sports like amateur boxing, fencing, judo, karate, taekwondo, and wrestling. A systematic search was conducted in the electronic databases PubMed, Google-Scholar, and Science-Direct up to October 2017. Studies in combat sports were included that reported validation data (e.g., reliability, validity, sensitivity) of sport-specific tests. Overall, 39 studies were eligible for inclusion in this review. The majority of studies (74%) contained sample sizes <30 subjects. Nearly, 1/3 of the reviewed studies lacked a sufficient description (e.g., anthropometrics, age, expertise level) of the included participants. Seventy-two percent of studies did not sufficiently report inclusion/exclusion criteria of their participants. In 62% of the included studies, the description and/or inclusion of a familiarization session (s) was either incomplete or not existent. Sixty-percent of studies did not report any details about the stability of testing conditions. Approximately half of the studies examined reliability measures of the included sport-specific tests (intraclass correlation coefficient [ICC] = 0.43-1.00). Content validity was addressed in all included studies, criterion validity (only the concurrent aspect of it) in approximately half of the studies with correlation coefficients ranging from r = -0.41 to 0.90. Construct validity was reported in 31% of the included studies and predictive validity in only one. Test sensitivity was addressed in 13% of the included studies. The majority of studies (64%) ignored and/or provided incomplete information on test feasibility and methodological limitations of the sport-specific test. In 28% of the included studies, insufficient information or a complete lack of information was provided in the respective field of the test application. Several methodological gaps exist in studies that used sport-specific performance tests in Olympic combat sports. Additional research should adopt more rigorous validation procedures in the application and description of sport-specific performance tests in Olympic combat sports.

Aspect-Oriented Business Process Modeling with AO4BPMN

NASA Astrophysics Data System (ADS)

Charfi, Anis; Müller, Heiko; Mezini, Mira

Many crosscutting concerns in business processes need to be addressed already at the business process modeling level such as compliance, auditing, billing, and separation of duties. However, existing business process modeling languages including OMG's Business Process Modeling Notation (BPMN) lack appropriate means for expressing such concerns in a modular way. In this paper, we motivate the need for aspect-oriented concepts in business process modeling languages and propose an aspect-oriented extension to BPMN called AO4BPMN. We also present a graphical editor supporting that extension.

Aspects of science engagement, student background, and school characteristics: Impacts on science achievement of U.S. students

NASA Astrophysics Data System (ADS)

Grabau, Larry J.

Science achievement of U.S. students has lagged significantly behind other nations; educational reformers have suggested science engagement may enhance this critical measure. The 2006 Program for International Student Assessment (PISA) was science-focused and measured science achievement along with nine aspects of science engagement: science self-efficacy, science self-concept, enjoyment of science, general interest in learning science, instrumental motivation for science, future-oriented science motivation, general value of science, personal value of science, and science-related activities. I used multilevel modeling techniques to address both aspects of science engagement and science achievement as outcome variables in the context of student background and school characteristics. Treating aspects of science engagement as outcome variables provided tests for approaches for their enhancement; meanwhile, treating science achievement as the outcome variable provided tests for the influence of the aspects of science engagement on science achievement under appropriate controls. When aspects of science engagement were treated as outcome variables, gender and father's SES had frequent (significant) influences, as did science teaching strategies which focused on applications or models and hands-on activities over-and-above influences of student background and other school characteristics. When science achievement was treated as the outcome variable, each aspect of science engagement was significant, and eight had medium or large effect sizes (future-oriented science motivation was the exception). The science teaching strategy which involved hands-on activities frequently enhanced science achievement over-and-above influences of student background and other school characteristics. Policy recommendations for U.S. science educators included enhancing eight aspects of science engagement and implementing two specific science teaching strategies (focus on applications or models and hands-on activities). Focused implementation of these research findings could enhance both science engagement and science achievement of U.S. students. I identified five keylimitations of my research project: the age of the dataset, the lack of racial/ethnic identifiers, the low proportion of student-level variance accounted for by multilevel models with aspects of science engagement as outcome variables, the lack of class-level measures, and the lack of inclusion of students' epistemological and fixed/flexible beliefs. These limitations provide opportunities for further investigations into these critical issues in science education.

Assessing a Critical Aspect of Construct Continuity when Test Specifications Change or Test Forms Deviate from Specifications

ERIC Educational Resources Information Center

Liu, Jinghua; Dorans, Neil J.

2013-01-01

We make a distinction between two types of test changes: inevitable deviations from specifications versus planned modifications of specifications. We describe how score equity assessment (SEA) can be used as a tool to assess a critical aspect of construct continuity, the equivalence of scores, whenever planned changes are introduced to testing…

Associations between faith, distress and mental adjustment--a Danish survivorship study.

PubMed

Johannessen-Henry, Christine Tind; Deltour, Isabelle; Bidstrup, Pernille Envold; Dalton, Susanne O; Johansen, Christoffer

2013-02-01

Several studies have suggested that religion and spirituality are important for overcoming psychological distress and adjusting mentally to cancer, but these studies did not differentiate between spiritual well-being and specific aspects of faith. We examined the extent to which spiritual well-being, the faith dimension of spiritual well-being and aspects of performed faith are associated with distress and mental adjustment among cancer patients. In a cross-sectional design, 1043 survivors of various cancers filled in a questionnaire on spiritual well-being (FACIT-Sp-12), specific aspects of faith ('belief in a god', 'belief in a god with whom I can talk' and 'experiences of god or a higher power'), religious community and church attendance (DUREL), distress (POMS-SF), adjustment to cancer (Mini-MAC) and sociodemographic factors. Linear regression models were used to analyze the associations between exposure (spiritual well-being and specific faith aspects) and outcome (distress and adjustment to cancer) with adjustment for age, gender, cancer diagnosis and physical and social well-being. Higher spiritual well-being was associated with less total distress (β = -0.79, CI -0.92; -0.66) and increased adjustment to cancer (fighting spirit, anxious preoccupation, helplessness-hopelessness). Specific aspects of faith were associated with high confusion-bewilderment and tension-anxiety, but also lower score on vigor-activity, and with higher anxious-preoccupation, both higher and lower cognitive avoidance, but also more fighting spirit. As hypothesized, spiritual well-being were associated with less distress and better mental adjustment. However, specific aspects of faith were both positively and negatively associated with distress and mental adjustment. The results illustrate the complexity of associations between spiritual well-being and specific aspects of faith with psychological function among cancer survivors.

Rationale, design and conduct of a randomised controlled trial evaluating a primary care-based complex intervention to improve the quality of life of heart failure patients: HICMan (Heidelberg Integrated Case Management)

PubMed Central

Peters-Klimm, Frank; Müller-Tasch, Thomas; Schellberg, Dieter; Gensichen, Jochen; Muth, Christiane; Herzog, Wolfgang; Szecsenyi, Joachim

2007-01-01

Background Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The delivery of care for these patients has been criticized and new strategies addressing crucial domains of care have been shown to be effective on patients' health outcomes, although these trials were conducted in secondary care or in highly organised Health Maintenance Organisations. It remains unclear whether a comprehensive primary care-based case management for the treating general practitioner (GP) can improve patients' QoL. Methods/Design HICMan is a randomised controlled trial with patients as the unit of randomisation. Aim is to evaluate a structured, standardized and comprehensive complex intervention for patients with CHF in a 12-months follow-up trial. Patients from intervention group receive specific patient leaflets and documentation booklets as well as regular monitoring and screening by a prior trained practice nurse, who gives feedback to the GP upon urgency. Monitoring and screening address aspects of disease-specific self-management, (non)pharmacological adherence and psychosomatic and geriatric comorbidity. GPs are invited to provide a tailored structured counselling 4 times during the trial and receive an additional feedback on pharmacotherapy relevant to prognosis (data of baseline documentation). Patients from control group receive usual care by their GPs, who were introduced to guideline-oriented management and a tailored health counselling concept. Main outcome measurement for patients' QoL is the scale physical functioning of the SF-36 health questionnaire in a 12-month follow-up. Secondary outcomes are the disease specific QoL measured by the Kansas City Cardiomyopathy questionnaire (KCCQ), depression and anxiety disorders (PHQ-9, GAD-7), adherence (EHFScBS and SANA), quality of care measured by an adapted version of the Patient Chronic Illness Assessment of Care questionnaire (PACIC) and NT-proBNP. In addition, comprehensive clinical data are collected about health status, comorbidity, medication and health care utilisation. Discussion As the targeted patient group is mostly cared for and treated by GPs, a comprehensive primary care-based guideline implementation including somatic, psychosomatic and organisational aspects of the delivery of care (HICMAn) is a promising intervention applying proven strategies for optimal care. Trial registration Current Controlled Trials ISRCTN30822978. PMID:17716364

Rationale, design and conduct of a randomised controlled trial evaluating a primary care-based complex intervention to improve the quality of life of heart failure patients: HICMan (Heidelberg Integrated Case Management).

PubMed

Peters-Klimm, Frank; Müller-Tasch, Thomas; Schellberg, Dieter; Gensichen, Jochen; Muth, Christiane; Herzog, Wolfgang; Szecsenyi, Joachim

2007-08-23

Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The delivery of care for these patients has been criticized and new strategies addressing crucial domains of care have been shown to be effective on patients' health outcomes, although these trials were conducted in secondary care or in highly organised Health Maintenance Organisations. It remains unclear whether a comprehensive primary care-based case management for the treating general practitioner (GP) can improve patients' QoL. HICMan is a randomised controlled trial with patients as the unit of randomisation. Aim is to evaluate a structured, standardized and comprehensive complex intervention for patients with CHF in a 12-months follow-up trial. Patients from intervention group receive specific patient leaflets and documentation booklets as well as regular monitoring and screening by a prior trained practice nurse, who gives feedback to the GP upon urgency. Monitoring and screening address aspects of disease-specific self-management, (non)pharmacological adherence and psychosomatic and geriatric comorbidity. GPs are invited to provide a tailored structured counselling 4 times during the trial and receive an additional feedback on pharmacotherapy relevant to prognosis (data of baseline documentation). Patients from control group receive usual care by their GPs, who were introduced to guideline-oriented management and a tailored health counselling concept. Main outcome measurement for patients' QoL is the scale physical functioning of the SF-36 health questionnaire in a 12-month follow-up. Secondary outcomes are the disease specific QoL measured by the Kansas City Cardiomyopathy questionnaire (KCCQ), depression and anxiety disorders (PHQ-9, GAD-7), adherence (EHFScBS and SANA), quality of care measured by an adapted version of the Patient Chronic Illness Assessment of Care questionnaire (PACIC) and NT-proBNP. In addition, comprehensive clinical data are collected about health status, comorbidity, medication and health care utilisation. As the targeted patient group is mostly cared for and treated by GPs, a comprehensive primary care-based guideline implementation including somatic, psychosomatic and organisational aspects of the delivery of care (HICMAn) is a promising intervention applying proven strategies for optimal care.

Functional Roles of Neural Preparatory Processes in a Cued Stroop Task Revealed by Linking Electrophysiology with Behavioral Performance.

PubMed

Wang, Chao; Ding, Mingzhou; Kluger, Benzi M

2015-01-01

It is well established that cuing facilitates behavioral performance and that different aspects of instructional cues evoke specific neural preparatory processes in cued task-switching paradigms. To deduce the functional role of these neural preparatory processes the majority of studies vary aspects of the experimental paradigm and describe how these variations alter markers of neural preparatory processes. Although these studies provide important insights, they also have notable limitations, particularly in terms of understanding the causal or functional relationship of neural markers to cognitive and behavioral processes. In this study, we sought to address these limitations and uncover the functional roles of neural processes by examining how variability in the amplitude of neural preparatory processes predicts behavioral performance to subsequent stimuli. To achieve this objective 16 young adults were recruited to perform a cued Stroop task while their brain activity was measured using high-density electroencephalography. Four temporally overlapping but functionally and topographically distinct cue-triggered event related potentials (ERPs) were identified: 1) A left-frontotemporal negativity (250-700 ms) that was positively associated with word-reading performance; 2) a midline-frontal negativity (450-800 ms) that was positively associated with color-naming and incongruent performance; 3) a left-frontal negativity (450-800 ms) that was positively associated with switch trial performance; and 4) a centroparietal positivity (450-800 ms) that was positively associated with performance for almost all trial types. These results suggest that at least four dissociable cognitive processes are evoked by instructional cues in the present task, including: 1) domain-specific task facilitation; 2) switch-specific task-set reconfiguration; 3) preparation for response conflict; and 4) proactive attentional control. Examining the relationship between ERPs and behavioral performance provides a functional link between neural markers and the cognitive processes they index.

NASA Aerospace Flight Battery Program: Wet Life of Nickel-Hydrogen (Ni-H2) Batteries. Volume 2, Part 3; Appendices

NASA Technical Reports Server (NTRS)

Jung, David S,; Lee, Leonine S.; Manzo, Michelle A.

2010-01-01

This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 3 - Volume II Appendices to Part 3 - Volume I.

NASA Aerospace Flight Battery Program: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements. Volume 2/Part 2

NASA Technical Reports Server (NTRS)

Jung, David S.; Manzo, Michelle A.

2010-01-01

This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 2 - Volume II Appendix A to Part 2 - Volume I.

Measuring the concept of impact of childhood disability on parents: validation of a multidimensional measurement in a cerebral palsy population.

PubMed

Guyard, Audrey; Michelsen, Susan I; Arnaud, Catherine; Lyons, Alan; Cans, Christine; Fauconnier, Jérôme

2012-01-01

Living with a child with a disability can affect family life in various domains. Impacts on time, expenses, work, relationships within the family, social relationships and physical and psychological health can be observed. The Family Impact of Childhood Disability (FICD) is a specific instrument designed to assess this situation. Used in a cross-sectional survey, this questionnaire was extended to consider two missing aspects: impact on work and health (FICD+4). This paper addresses the psychometric qualities of the FICD in Europe among parents living with an adolescent with cerebral palsy. Expecting the FICD+4 could assess detailed impact dimensions, an exploratory analysis was conducted. We interviewed 242 families of 13- to 17-year-old adolescents with cerebral palsy living in Europe. Good psychometric properties were found in negative and positive FICD scales and in six underlying factors extracted from exploratory factor analysis on FICD+4. These results support the psychometric validity of the FICD in the assessment of the impact of disability in European families who live with an adolescent with cerebral palsy. They also highlight the multifaceted aspects of the impact of childhood disability on the family and suggest that the FICD+4 is a good tool for assessing specific negative impacts on time, finances, work, social relationships and positive impacts on parental feeling and family attitude. This scale needs further validation and could be helpful for research and clinical interventions. Copyright © 2012 Elsevier Ltd. All rights reserved.

The Essential Properties of Yoga Questionnaire (EPYQ): Psychometric Properties.

PubMed

Park, Crystal L; Elwy, A Rani; Maiya, Meghan; Sarkin, Andrew J; Riley, Kristen E; Eisen, Susan V; Gutierrez, Ian; Finkelstein-Fox, Lucy; Lee, Sharon Y; Casteel, Danielle; Braun, Tosca; Groessl, Erik J

2018-03-02

Yoga interventions are heterogeneous and vary along multiple dimensions. These dimensions may affect mental and physical health outcomes in different ways or through different mechanisms. However, most studies of the effects of yoga on health do not adequately describe or quantify the components of the interventions being implemented. This lack of detail prevents researchers from making comparisons across studies and limits our understanding of the relative effects of different aspects of yoga interventions. To address this problem, we developed the Essential Properties of Yoga Questionnaire (EPYQ), which allows researchers to objectively characterize their interventions. We present here the reliability and validity data from the final phases of this measure-development project. Analyses identified fourteen key dimensions of yoga interventions measured by the EPYQ: acceptance/compassion, bandhas, body awareness, breathwork, instructor mention of health benefits, individual attention, meditation and mindfulness, mental and emotional awareness, physicality, active postures, restorative postures, social aspects, spirituality, and yoga philosophy. The EPYQ demonstrated good reliability, as assessed by internal consistency and test-retest reliability analysis, and evidence suggests that the EPYQ is a valid measure of multiple dimensions of yoga. The measure is ready for use by clinicians and researchers. Results indicate that, currently, trained objective raters should score interventions to avoid reference frame errors and potential rating bias, but alternative approaches may be developed. The EPYQ will allow researchers to link specific yoga dimensions to identifiable health outcomes and optimize the design of yoga interventions for specific conditions.

Environmental Hazards Assessment Program. Quarterly report, January 1994--March 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-05-04

The objectives of the EHAP program are to: Develop a holistic, national basis for risk assessment, risk management and risk communication; Develop a pool of talented scientists and experts in cleanup activities, especially in human health aspects, and; Identify needs and develop programs addressing the critical shortage of well-educated, highly-skilled technical and scientific personnel to address the health oriented aspects of environmental restoration and waste management. This report describes activities and reports on progress for the third quarter of year two (January-March, 1994) of the grant. To better accomplish objectives, grant efforts are organized into three major elements: The Crossroadsmore » of Humanity Series; Research, Science and Education Programs; and Program Management. The Crossroads of Humanity Series charted a new course, incorporating lessons learned during previous quarters into a series of programs designed to address environmental issues in a real world setting. Reports are included on the various research programs with milestones and deliverables from the third quarter.« less

ENERGY SYSTEM DEVELOPMENT AND LOAD MANAGEMENT THROUGH THE REHABILITATION AND RETURN TO PLAY PROCESS.

PubMed

Morrison, Scot; Ward, Patrick; duManoir, Gregory R

2017-08-01

Return-to-play from injury is a complex process involving many factors including the balancing of tissue healing rates with the development of biomotor abilities. This process requires interprofessional cooperation to ensure success. An often-overlooked aspect of return-to-play is the development and maintenance of sports specific conditioning while monitoring training load to ensure that the athlete's training stimulus over the rehabilitation period is appropriate to facilitate a successful return to play. The purpose of this clinical commentary is to address the role of energy systems training as part of the return-to-play process. Additionally the aim is to provide practitioners with an overview of practical sports conditioning training methods and monitoring strategies to allow them to direct and quantify the return-to-play process. 5.

Design and Stability of an On-Orbit Attitude Control System Using Reaction Control Thrusters

NASA Technical Reports Server (NTRS)

Hall, Robert A.; Hough, Steven; Orphee, Carolina; Clements, Keith

2015-01-01

Principles for the design and stability of a spacecraft on-orbit attitude control system employing on-off Reaction Control System (RCS) thrusters is presented. Both the vehicle dynamics and the control system actuators are inherently nonlinear, hence traditional linear control system design approaches are not directly applicable. This paper has three main aspects: It summarizes key RCS control System design principles from the Space Shuttle and Space Station programs, it demonstrates a new approach to develop a linear model of a phase plane control system using describing functions, and applies each of these to the initial development of the NASA's next generation of upper stage vehicles. Topics addressed include thruster hardware specifications, phase plane design and stability, jet selection approaches, filter design metrics, and automaneuver logic.

Competency in integrative psychotherapy: perspectives on training and supervision.

PubMed

Boswell, James F; Nelson, Dana L; Nordberg, Samuel S; McAleavey, Andrew A; Castonguay, Louis G

2010-03-01

Increasingly, many psychotherapists identify with an integrative approach to psychotherapy. In recent years, more attention has been directed toward the operationalization and evaluation of competence in professional psychology and health care service delivery. Aspects of integrative psychotherapy competency may differ from competency in other psychotherapy orientations, although convergence is more often the case. Despite the potential differences, there exist very few formal training programs or guidelines to systematically guide clinicians in developing a competent integrative practice. This paper attempts to distill the essential elements of competent integrative psychotherapy practice and focuses on how these might be developed in training and supervision. We address most of these complex issues from a specific integrative perspective: principle-based assimilative integration. PsycINFO Database Record (c) 2010 APA, all rights reserved

Anaerobic microbial dehalogenation of organohalides-state of the art and remediation strategies.

PubMed

Nijenhuis, Ivonne; Kuntze, Kevin

2016-04-01

Contamination and remediation of groundwater with halogenated organics and understanding of involved microbial reactions still poses a challenge. Over the last years, research in anaerobic microbial dehalogenation has advanced in many aspects providing information about the reaction, physiology of microorganisms as well as approaches to investigate the activity of microorganisms in situ. Recently published crystal structures of reductive dehalogenases (Rdh), heterologous expression systems and advanced analytical, proteomic and stable isotope approaches allow addressing the overall reaction and specific enzymes as well as co-factors involved during anaerobic microbial dehalogenation. In addition to Dehalococcoides spp., Dehalobacter and Dehalogenimonas strains have been recognized as important and versatile organohalide respirers. Together, these provide perspectives for integrated concepts allowing to improve and monitor in situ biodegradation. Copyright © 2015 Elsevier Ltd. All rights reserved.

[The electrocardiogram in the paediatric age group].

PubMed

Sanches, M; Coelho, A; Oliveira, E; Lopes, A

2014-09-01

A properly interpreted electrocardiogram (ECG) provides important information and is an inexpensive and easy test to perform. It continues to be the method of choice for the diagnosis of arrhythmias. Although the principles of cardiac electrophysiology are the same, there are anatomical and physiological age-dependent changes which produce specific alterations in the paediatric ECG, and which may be misinterpreted as pathological. The intention of this article is to address in a systematic way the most relevant aspects of the paediatric ECG, to propose a possible reading scheme of the ECG and to review the electrocardiograph tracings most frequently found in the paediatric age group. Copyright © 2013 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España. All rights reserved.

Influence of school architecture and design on healthy eating: a review of the evidence.

PubMed

Frerichs, Leah; Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew J; Yaroch, Amy L; Siahpush, Mohammad; Tibbits, Melissa; Huang, Terry T-K

2015-04-01

We examined evidence regarding the influence of school physical environment on healthy-eating outcomes. We applied a systems perspective to examine multiple disciplines' theoretical frameworks and used a mixed-methods systematic narrative review method, considering both qualitative and quantitative sources (published through March 2014) for inclusion. We developed a causal loop diagram from 102 sources identified. We found evidence of the influence of many aspects of a school's physical environment on healthy-eating outcomes. The causal loop diagram highlights multilevel and interrelated factors and elucidates the specific roles of design and architecture in encouraging healthy eating within schools. Our review highlighted the gaps in current evidence and identified areas of research needed to refine and expand school architecture and design strategies for addressing healthy eating.

Influence of School Architecture and Design on Healthy Eating: A Review of the Evidence

PubMed Central

Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew J.; Yaroch, Amy L.; Siahpush, Mohammad; Tibbits, Melissa; Huang, Terry T.-K.

2015-01-01

We examined evidence regarding the influence of school physical environment on healthy-eating outcomes. We applied a systems perspective to examine multiple disciplines’ theoretical frameworks and used a mixed-methods systematic narrative review method, considering both qualitative and quantitative sources (published through March 2014) for inclusion. We developed a causal loop diagram from 102 sources identified. We found evidence of the influence of many aspects of a school’s physical environment on healthy-eating outcomes. The causal loop diagram highlights multilevel and interrelated factors and elucidates the specific roles of design and architecture in encouraging healthy eating within schools. Our review highlighted the gaps in current evidence and identified areas of research needed to refine and expand school architecture and design strategies for addressing healthy eating. PMID:25713964

Mentoring for the New Millennium.

PubMed

Walker, William O; Kelly, Patrick C; Hume, Roderick F

2002-12-01

The challenges and benefits of a formal mentoring program are considered within the context of learning organizations: specifically, graduate medical education and professional development. While no single definition addresses every aspect of mentoring, this process is a distinct one with established traditions and expectations. The core requirements of attraction, action and affect remain and are essential for this adult developmental process to be successful. This paper's review of the literature supports the belief that mentoring has value, even into the next millennium, with some conceptual evolution. We are encouraging a paradigm shift from the traditional dyad model of mentoring to a triad model: organization, mentor, and protégé. The future development of outcome measures will be a necessary goal to demonstrate that both personal and organizational goals can coexist.

Terror Medicine as Part of the Medical School Curriculum

PubMed Central

Cole, Leonard A.; Wagner, Katherine; Scott, Sandra; Connell, Nancy D.; Cooper, Arthur; Kennedy, Cheryl Ann; Natal, Brenda; Lamba, Sangeeta

2014-01-01

Terror medicine, a field related to emergency and disaster medicine, focuses on medical issues ranging from preparedness to psychological manifestations specifically associated with terrorist attacks. Calls to teach aspects of the subject in American medical schools surged after the 2001 jetliner and anthrax attacks. Although the threat of terrorism persists, terror medicine is still addressed erratically if at all in most medical schools. This paper suggests a template for incorporating the subject throughout a 4-year medical curriculum. The instructional framework culminates in a short course for fourth year students, such as one recently introduced at Rutgers New Jersey Medical School, Newark, NJ, USA. The proposed 4-year Rutgers curriculum serves as a model that could assist other medical schools contemplating the inclusion of terror medicine in pre-clerkship and clerkship training. PMID:25309891

Terror medicine as part of the medical school curriculum.

PubMed

Cole, Leonard A; Wagner, Katherine; Scott, Sandra; Connell, Nancy D; Cooper, Arthur; Kennedy, Cheryl Ann; Natal, Brenda; Lamba, Sangeeta

2014-01-01

Terror medicine, a field related to emergency and disaster medicine, focuses on medical issues ranging from preparedness to psychological manifestations specifically associated with terrorist attacks. Calls to teach aspects of the subject in American medical schools surged after the 2001 jetliner and anthrax attacks. Although the threat of terrorism persists, terror medicine is still addressed erratically if at all in most medical schools. This paper suggests a template for incorporating the subject throughout a 4-year medical curriculum. The instructional framework culminates in a short course for fourth year students, such as one recently introduced at Rutgers New Jersey Medical School, Newark, NJ, USA. The proposed 4-year Rutgers curriculum serves as a model that could assist other medical schools contemplating the inclusion of terror medicine in pre-clerkship and clerkship training.

Standard for Models and Simulations

NASA Technical Reports Server (NTRS)

Steele, Martin J.

2016-01-01

This NASA Technical Standard establishes uniform practices in modeling and simulation to ensure essential requirements are applied to the design, development, and use of models and simulations (MS), while ensuring acceptance criteria are defined by the program project and approved by the responsible Technical Authority. It also provides an approved set of requirements, recommendations, and criteria with which MS may be developed, accepted, and used in support of NASA activities. As the MS disciplines employed and application areas involved are broad, the common aspects of MS across all NASA activities are addressed. The discipline-specific details of a given MS should be obtained from relevant recommended practices. The primary purpose is to reduce the risks associated with MS-influenced decisions by ensuring the complete communication of the credibility of MS results.

Virtual reality and gaming systems to improve walking and mobility for people with musculoskeletal and neuromuscular conditions.

PubMed

Deutsch, Judith E

2009-01-01

Improving walking for individuals with musculoskeletal and neuromuscular conditions is an important aspect of rehabilitation. The capabilities of clinicians who address these rehabilitation issues could be augmented with innovations such as virtual reality gaming based technologies. The chapter provides an overview of virtual reality gaming based technologies currently being developed and tested to improve motor and cognitive elements required for ambulation and mobility in different patient populations. Included as well is a detailed description of a single VR system, consisting of the rationale for development and iterative refinement of the system based on clinical science. These concepts include: neural plasticity, part-task training, whole task training, task specific training, principles of exercise and motor learning, sensorimotor integration, and visual spatial processing.

Functional requirements for the man-vehicle systems research facility. [identifying and correcting human errors during flight simulation

NASA Technical Reports Server (NTRS)

Clement, W. F.; Allen, R. W.; Heffley, R. K.; Jewell, W. F.; Jex, H. R.; Mcruer, D. T.; Schulman, T. M.; Stapleford, R. L.

1980-01-01

The NASA Ames Research Center proposed a man-vehicle systems research facility to support flight simulation studies which are needed for identifying and correcting the sources of human error associated with current and future air carrier operations. The organization of research facility is reviewed and functional requirements and related priorities for the facility are recommended based on a review of potentially critical operational scenarios. Requirements are included for the experimenter's simulation control and data acquisition functions, as well as for the visual field, motion, sound, computation, crew station, and intercommunications subsystems. The related issues of functional fidelity and level of simulation are addressed, and specific criteria for quantitative assessment of various aspects of fidelity are offered. Recommendations for facility integration, checkout, and staffing are included.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Esfahani, M. Nasr; Yilmaz, M.; Sonne, M. R.

The trend towards nanomechanical resonator sensors with increasing sensitivity raises the need to address challenges encountered in the modeling of their mechanical behavior. Selecting the best approach in mechanical response modeling amongst the various potential computational solid mechanics methods is subject to controversy. A guideline for the selection of the appropriate approach for a specific set of geometry and mechanical properties is needed. In this study, geometrical limitations in frequency response modeling of flexural nanomechanical resonators are investigated. Deviation of Euler and Timoshenko beam theories from numerical techniques including finite element modeling and Surface Cauchy-Born technique are studied. The resultsmore » provide a limit beyond which surface energy contribution dominates the mechanical behavior. Using the Surface Cauchy-Born technique as the reference, a maximum error on the order of 50 % is reported for high-aspect ratio resonators.« less

Making the Most Out of School-Based Prevention: Lessons from the Social and Emotional Aspects of Learning (SEAL) Programme

ERIC Educational Resources Information Center

Humphrey, Neil; Lendrum, Ann; Wigelsworth, Michael

2013-01-01

This paper considers the role played by universal, school-based social and emotional learning (SEL) programmes in addressing the mental health needs of children and young people. Theory and research in the field are discussed. Particular attention is paid to the social and emotional aspects of learning (SEAL) programme in England, a flagship…

Institutional Corruption in Higher Education: Analysis of Causes and Reforms at the Second-Largest Institution of Higher Education in Illinois

ERIC Educational Resources Information Center

Kresse, William J.

2017-01-01

Corruption in higher education is an emerging topic in the field of education research. (Osipian 2008). Different aspects of such corruption have been addressed in numerous papers by various researchers. These papers indicate different aspects of the problem. Many of the papers evidence the global nature of this problem by highlighting corruption…

A Cross-Cultural Analysis of the Relations of Physical and Relational Aggression with Peer Victimization

ERIC Educational Resources Information Center

Bass, Ellyn Charlotte; Saldarriaga, Lina; Cunha, Josafa; Chen, Bin-Bin; Santo, Jonathan Bruce; Bukowski, William M.

2018-01-01

To better address the many consequences of peer victimization, research must identify not only aspects of individuals that put them at risk for victimization, such as aggression, but also aspects of the context that influence the extent of that risk. To this end, this study examined the contextual influences of gender, same-sex peer group norms of…

Student self-assessment in an interactive learning environment: Technological tools for scaffolding and understanding self-assessment practices

NASA Astrophysics Data System (ADS)

Eslinger, Eric Martin

Metacognitive skills are a crucial component of a successful learning career. We define metacognition as the ability to plan, monitor progress toward a goal, reflect on the quality of work and process, and revise the work or plan accordingly. By explicitly addressing certain metacognitive practices in classrooms, researchers have observed improved learning outcomes in both science and mathematical problem solving. Although these efforts were successful, they were also limited in the range of skills that could be addressed at one time and the methods used to address them due to the static nature inherent in traditional pencil-and-paper format. We wished to address these skills in a more dynamic, continuous representation such as that afforded by a computerized learning environment. This paper outlines such an environment and describes pedagogical activities afforded by the system. The ThinkerTools group developed and tested a software scaffold for inquiry projects in a middle-school classroom. By analyzing student use of the software tool, three forms of self-assessment activity were noted: integrated, task and project self-assessment. Each assessment form was related to the degree of interleaving between assessment and work the students engaged in as they developed their inquiry products. I argue that the integrated forms of assessment are more beneficial to student learning, and show that there is a significant relationship between active self-assessment forms and measures of student achievement and product quality. Through the use of case studies including video analysis, I address specific student self-assessment activity that utilized the software as well as self-assessment that took place outside of the software. A model of student self-assessment activity was created, highlighting aspects of activity that afford more productive self-assessment episodes.

Towards a cross-domain interoperable framework for natural hazards and disaster risk reduction information

NASA Astrophysics Data System (ADS)

Tomas, Robert; Harrison, Matthew; Barredo, José I.; Thomas, Florian; Llorente Isidro, Miguel; Cerba, Otakar; Pfeiffer, Manuela

2014-05-01

The vast amount of information and data necessary for comprehensive hazard and risk assessment presents many challenges regarding the lack of accessibility, comparability, quality, organisation and dissemination of natural hazards spatial data. In order to mitigate these limitations an interoperable framework has been developed in the framework of the development of legally binding Implementing rules of the EU INSPIRE Directive1* aiming at the establishment of the European Spatial Data Infrastructure. The interoperability framework is described in the Data Specification on Natural risk zones - Technical Guidelines (DS) document2* that was finalized and published on 10.12. 2013. This framework provides means for facilitating access, integration, harmonisation and dissemination of natural hazard data from different domains and sources. The objective of this paper is twofold. Firstly, the paper demonstrates the applicability of the interoperable framework developed in the DS and highlights the key aspects of the interoperability to the various natural hazards communities. Secondly, the paper "translates" into common language the main features and potentiality of the interoperable framework of the DS for a wider audience of scientists and practitioners in the natural hazards domain. Further in this paper the main five aspects of the interoperable framework will be presented. First, the issue of a common terminology for the natural hazards domain will be addressed. A common data model to facilitate cross domain data integration will follow secondly. Thirdly, the common methodology developed to provide qualitative or quantitative assessments of natural hazards will be presented. Fourthly, the extensible classification schema for natural hazards developed from a literature review and key reference documents from the contributing community of practice will be shown. Finally, the applicability of the interoperable framework for the various stakeholder groups will be also presented. This paper closes discussing open issues and next steps regarding the sustainability and evolution of the interoperable framework and missing aspects such as multi-hazard and multi-risk. --------------- 1*INSPIRE - Infrastructure for spatial information in Europe, http://inspire.ec.europa.eu 2*http://inspire.jrc.ec.europa.eu/documents/Data_Specifications/INSPIRE_DataSpecification_NZ_v3.0.pdf

Accessing global data from accelerator devices

DOEpatents

Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.; Sura, Zehra N.

2016-12-06

An aspect includes a table of contents (TOC) that was generated by a compiler being received at an accelerator device. The TOC includes an address of global data in a host memory space. The global data is copied from the address in the host memory space to an address in the device memory space. The address in the host memory space is obtained from the received TOC. The received TOC is updated to indicate that global data is stored at the address in the device memory space. A kernel that accesses the global data from the address in the device memory space is executed. The address in the device memory space is obtained based on contents of the updated TOC. When the executing is completed, the global data from the address in the device memory space is copied to the address in the host memory space.

Accessing global data from accelerator devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.

2016-12-06

An aspect includes a table of contents (TOC) that was generated by a compiler being received at an accelerator device. The TOC includes an address of global data in a host memory space. The global data is copied from the address in the host memory space to an address in the device memory space. The address in the host memory space is obtained from the received TOC. The received TOC is updated to indicate that global data is stored at the address in the device memory space. A kernel that accesses the global data from the address in the devicemore » memory space is executed. The address in the device memory space is obtained based on contents of the updated TOC. When the executing is completed, the global data from the address in the device memory space is copied to the address in the host memory space.« less

Library Services in Distance Education. Proceedings of a National Seminar (Adelaide, Australia, August 22-23, 1985).

ERIC Educational Resources Information Center

Gray, John, Ed.

This seminar addressed various aspects of the provision of library and other services to external students. Resolutions carried at the end of the seminar are noted, and the full text is provided for the opening address, which summarizes the activities of the Commonwealth Tertiary Education Commission Standing Committee on External Studies, and the…