Sample records for adjacent one-degree blocks

  1. Second-degree atrioventricular block.

    PubMed

    Zipes, D P

    1979-09-01

    1) While it is possible only one type of second-degree AV block exists electrophysiologically, the available data do not justify such a conclusion and it would seem more appropriate to remain a "splitter," and advocate separation and definition of multiple mechanisms, than to be a "lumper," and embrace a unitary concept. 2) The clinical classification of type I and type II AV block, based on present scalar electrocardiographic criteria, for the most part accurately differentiates clinically important categories of patients. Such a classification is descriptive, but serves a useful function and should be preserved, taking into account the caveats mentioned above. The site of block generally determines the clinical course for the patient. For most examples of AV block, the type I and type II classification in present use is based on the site of block. Because block in the His-Purkinje system is preceded by small or nonmeasurable increments, it is called type II AV block; but the very fact that it is preceded by small increments is because it occurs in the His-Purkinje system. Similar logic can be applied to type I AV block in the AV node. Exceptions do occur. If the site of AV block cannot be distinguished with certainity from the scalar ECG, an electrophysiologic study will generally reveal the answer.

  2. Second diastolic pulmonary venous flow and isolated late diastolic mitral valve regurgitation in first-degree atrioventricular block.

    PubMed

    Leibundgut, Gregor; Bernheim, Alain M

    2010-04-01

    The authors report the case of a 77-year-old male patient with sinus rhythm and a first-degree atrioventricular (AV) block who was referred for echocardiographic follow-up 18 years after aortic valve replacement. Left ventricular systolic function as well as the function of the aortic prosthesis was normal. Systolic mitral regurgitation (MR) was virtually absent, but isolated late diastolic MR was detected by colour Doppler imaging. Coincidental to the occurrence of diastolic MR, a second late diastolic forward flow in the pulmonary veins was observed. Therefore, during the prolonged left atrial relaxation caused by first-degree AV block, the left atrial pressure drops below the pressure in both adjacent chambers in late diastole, resulting in both late diastolic MR and a second diastolic pulmonary venous forward flow.

  3. Second-Degree Atrioventricular Block Occurring After Tooth Extraction.

    PubMed

    Kamatani, Takaaki; Akizuki, Ayako; Kondo, Seiji; Shirota, Tatsuo

    Although cardiac arrhythmias are occasionally associated with dental extractions and dental anesthesia, atrioventricular block is rarely seen during dental procedures. We report a rare case of type I second-degree atrioventricular block (Wenckebach phenomenon) occurring after bilateral extraction of impacted mandibular third molars under general anesthesia in a 16-year-old Japanese girl. Under consultation with a cardiovascular physician, we carefully monitored the patient's vital signs postoperatively, including blood pressure, oxygen saturation, and electrocardiogram, using a bedside monitor. Her postoperative course was uneventful. A 12-lead electrocardiogram the following day revealed no abnormality. In this case, we hypothesize that extubation of the nasotracheal tube or oral/pharyngeal suction might have triggered a vagal reflex that caused type I second-degree atrioventricular block. Our experience indicates that standard cardiovascular monitoring should be used for patients undergoing dental treatment under general anesthesia, even for young, healthy patients, to prevent and detect cardiovascular emergencies.

  4. Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another

    PubMed Central

    Abdiche, Yasmina Noubia; Yeung, Andy Yik; Ni, Irene; Stone, Donna; Miles, Adam; Morishige, Winse; Rossi, Andrea; Strop, Pavel

    2017-01-01

    Here we describe how real-time label-free biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing one another’s binding towards their antigen via the formation of a transient trimolecular complex, antibodies can displace one another in a fully reversible and dose-dependent manner. Displacements can be readily identified when epitope binning assays are performed in a classical sandwich assay format whereby a solution antibody (analyte) is tested for binding to its antigen that is first captured via an immobilized antibody (ligand) because an inverted sandwiching response is observed when an analyte displaces a ligand, signifying the antigen’s unusually rapid dissociation from its ligand. In addition to classifying antibodies within a panel in terms of their ability to block or sandwich pair with one another, displacement provides a hybrid mechanism of competition. Using high-throughput epitope binning studies we demonstrate that displacements can be observed on any target, if the antibody panel contains appropriate epitope diversity. Unidirectional displacements occurring between disparate-affinity antibodies can generate apparent asymmetries in a cross-blocking experiment, confounding their interpretation. However, examining competition across a wide enough concentration range will often reveal that these displacements are reversible. Displacement provides a gentle and efficient way of eluting antigen from an otherwise high affinity binding partner which can be leveraged in designing reagents or therapeutic antibodies with unique properties. PMID:28060885

  5. Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another.

    PubMed

    Abdiche, Yasmina Noubia; Yeung, Andy Yik; Ni, Irene; Stone, Donna; Miles, Adam; Morishige, Winse; Rossi, Andrea; Strop, Pavel

    2017-01-01

    Here we describe how real-time label-free biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing one another's binding towards their antigen via the formation of a transient trimolecular complex, antibodies can displace one another in a fully reversible and dose-dependent manner. Displacements can be readily identified when epitope binning assays are performed in a classical sandwich assay format whereby a solution antibody (analyte) is tested for binding to its antigen that is first captured via an immobilized antibody (ligand) because an inverted sandwiching response is observed when an analyte displaces a ligand, signifying the antigen's unusually rapid dissociation from its ligand. In addition to classifying antibodies within a panel in terms of their ability to block or sandwich pair with one another, displacement provides a hybrid mechanism of competition. Using high-throughput epitope binning studies we demonstrate that displacements can be observed on any target, if the antibody panel contains appropriate epitope diversity. Unidirectional displacements occurring between disparate-affinity antibodies can generate apparent asymmetries in a cross-blocking experiment, confounding their interpretation. However, examining competition across a wide enough concentration range will often reveal that these displacements are reversible. Displacement provides a gentle and efficient way of eluting antigen from an otherwise high affinity binding partner which can be leveraged in designing reagents or therapeutic antibodies with unique properties.

  6. Image contrast enhancement using adjacent-blocks-based modification for local histogram equalization

    NASA Astrophysics Data System (ADS)

    Wang, Yang; Pan, Zhibin

    2017-11-01

    Infrared images usually have some non-ideal characteristics such as weak target-to-background contrast and strong noise. Because of these characteristics, it is necessary to apply the contrast enhancement algorithm to improve the visual quality of infrared images. Histogram equalization (HE) algorithm is a widely used contrast enhancement algorithm due to its effectiveness and simple implementation. But a drawback of HE algorithm is that the local contrast of an image cannot be equally enhanced. Local histogram equalization algorithms are proved to be the effective techniques for local image contrast enhancement. However, over-enhancement of noise and artifacts can be easily found in the local histogram equalization enhanced images. In this paper, a new contrast enhancement technique based on local histogram equalization algorithm is proposed to overcome the drawbacks mentioned above. The input images are segmented into three kinds of overlapped sub-blocks using the gradients of them. To overcome the over-enhancement effect, the histograms of these sub-blocks are then modified by adjacent sub-blocks. We pay more attention to improve the contrast of detail information while the brightness of the flat region in these sub-blocks is well preserved. It will be shown that the proposed algorithm outperforms other related algorithms by enhancing the local contrast without introducing over-enhancement effects and additional noise.

  7. Increased prevalence of third-degree atrioventricular block in patients with type II diabetes mellitus.

    PubMed

    Movahed, Mohammad-Reza; Hashemzadeh, Mehrtash; Jamal, M Mazen

    2005-10-01

    Diabetes mellitus (DM) is a major risk for cardiovascular disease and mortality. There is some evidence that third-degree atrioventricular (AV) block occurs more commonly in patients with DM. In this study, we evaluated any possible association between DM and third-degree AV block using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes in a very large inpatient database. We used patient treatment files containing discharge diagnoses using ICD-9 codes of inpatient treatment from all Veterans Health Administration hospitals. The cohort was stratified using the ICD-9-CM code for DM (n = 293,124), a control group with hypertension but no DM (n = 552,623), and the ICD-9 code for third-degree AV block (426.0) and smoking (305.1, V15.82). We performed multivariate analysis adjusting for coronary artery disease, congestive heart failure, smoking, and hyperlipidemia. Continuous and binary variables were analyzed using chi2 and Fisher exact tests. Third-degree AV block diagnosis was present in 3,240 of DM patients (1.1%) vs 3,367 patients (0.6%) in the control group. Using multivariate analysis, DM remained strongly associated with third-degree AV block (odds ratio, 3.1; 95% confidential interval, 3.0 to 3.3; p < 0.0001). Third-degree AV block occurs significantly more in patients with DM. This finding may, in part, explain the high cardiovascular mortality in DM patients.

  8. The One-Pot Directed Assembly of Cylinder-Forming Block Copolymer on Adjacent Chemical Patterns for Bimodal Patterning.

    PubMed

    Chang, Tzu-Hsuan; Xiong, Shisheng; Liu, Chi-Chun; Liu, Dong; Nealey, Paul F; Ma, Zhenqiang

    2017-09-01

    The direct self-assembly of cylinder-forming poly(styrene-block-methyl-methacrylate) (PS-b-PMMA) block copolymer is successfully assembled into two orientations, according to the underlying guiding pattern in different areas. Lying-down and perpendicular cylinders are formed, respectively, depending on the design of chemical pattern: sparse line/space pattern or hexagonal dot array. The first chemical pattern composed of prepatterned cross-linked polystyrene (XPS) line/space structure has a period (L S ) equal to twice the intercylinder period of the block copolymer (L 0 ). The PS-b-PMMA thin film on the prepared chemical template after thermal annealing forms a lying-down cylinder morphology when the width of the PS strips is less than the width of PS block in the PS-b-PMMA block copolymer. The morphology is only applicable at the discrete thickness of the PS-b-PMMA film. In addition to forming the lying-down cylinders directly on the XPS guiding pattern, the cylinder-forming block copolymer can also be assembled in a perpendicular way on the second guiding pattern (the hexagonal dot array). The block copolymer films are registered into two orientations in a single directed self-assembly process. The features of the assembled patterns are successfully transferred down to the silicon oxide substrate. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Maternal steroid therapy for fetuses with second-degree immune-mediated congenital atrioventricular block: a systematic review and meta-analysis.

    PubMed

    Ciardulli, Andrea; D'Antonio, Francesco; Magro-Malosso, Elena R; Manzoli, Lamberto; Anisman, Paul; Saccone, Gabriele; Berghella, Vincenzo

    2018-03-07

    To explore the effect of maternal fluorinated steroid therapy on fetuses affected by second-degree immune-mediated congenital atrioventricular block. Studies reporting the outcome of fetuses with second-degree immune-mediated congenital atrioventricular block diagnosed on prenatal ultrasound and treated with fluorinated steroids compared with those not treated were included. The primary outcome was the overall progression of congenital atrioventricular block to either continuous or intermittent third-degree congenital atrioventricular block at birth. Meta-analyses of proportions using random effect model and meta-analyses using individual data random-effect logistic regression were used. Five studies (71 fetuses) were included. The progression rate to congenital atrioventricular block at birth in fetuses treated with steroids was 52% (95% confidence interval 23-79) and in fetuses not receiving steroid therapy 73% (95% confidence interval 39-94). The overall rate of regression to either first-degree, intermittent first-/second-degree or sinus rhythm in fetuses treated with steroids was 25% (95% confidence interval 12-41) compared with 23% (95% confidence interval 8-44) in those not treated. Stable (constant) second-degree congenital atrioventricular block at birth was present in 11% (95% confidence interval 2-27) of cases in the treated group and in none of the newborns in the untreated group, whereas complete regression to sinus rhythm occurred in 21% (95% confidence interval 6-42) of fetuses receiving steroids vs. 9% (95% confidence interval 0-41) of those untreated. There is still limited evidence as to the benefit of administered fluorinated steroids in terms of affecting outcome of fetuses with second-degree immune-mediated congenital atrioventricular block. © 2018 Nordic Federation of Societies of Obstetrics and Gynecology.

  10. Fabrication routes for one-dimensional nanostructures via block copolymers

    NASA Astrophysics Data System (ADS)

    Tharmavaram, Maithri; Rawtani, Deepak; Pandey, Gaurav

    2017-05-01

    Nanotechnology is the field which deals with fabrication of materials with dimensions in the nanometer range by manipulating atoms and molecules. Various synthesis routes exist for the one, two and three dimensional nanostructures. Recent advancements in nanotechnology have enabled the usage of block copolymers for the synthesis of such nanostructures. Block copolymers are versatile polymers with unique properties and come in many types and shapes. Their properties are highly dependent on the blocks of the copolymers, thus allowing easy tunability of its properties. This review briefly focusses on the use of block copolymers for synthesizing one-dimensional nanostructures especially nanowires, nanorods, nanoribbons and nanofibers. Template based, lithographic, and solution based approaches are common approaches in the synthesis of nanowires, nanorods, nanoribbons, and nanofibers. Synthesis of metal, metal oxides, metal oxalates, polymer, and graphene one dimensional nanostructures using block copolymers have been discussed as well.

  11. Highly Efficient One-Pot Synthesis of COS-Based Block Copolymers by Using Organic Lewis Pairs.

    PubMed

    Yang, Jia-Liang; Cao, Xiao-Han; Zhang, Cheng-Jian; Wu, Hai-Lin; Zhang, Xing-Hong

    2018-01-31

    A one-pot synthesis of block copolymer with regioregular poly(monothiocarbonate) block is described via metal-free catalysis. Lewis bases such as guanidine, quaternary onium salts, and Lewis acid triethyl borane (TEB) were equivalently combined and used as the catalysts. By using polyethylene glycol (PEG) as the macromolecular chain transfer agent (CTA), narrow polydispersity block copolymers were obtained from the copolymerization of carbonyl sulfide (COS) and propylene oxide (PO). The block copolymers had a poly(monothiocarbonate) block with perfect alternating degree and regioregularity. Unexpectedly, the addition of CTA to COS/PO copolymerization system could dramatically improve the turnover frequency (TOF) of PO (up to 240 h -1 ), higher than that of the copolymerization without CTA. In addition, the conversion of CTA could be up to 100% in most cases, as revealed by ¹H NMR spectra. Of consequence, the number-average molecular weights ( M n s) of the resultant block copolymers could be regulated by varying the feed ratio of CTA to PO. Oxygen-sulfur exchange reaction (O/S ER), which can generate randomly distributed thiocarbonate and carbonate units, was effectively suppressed in all of the cases in the presence of CTA, even at 80 °C. This work presents a versatile method for synthesizing sulfur-containing block copolymers through a metal-free route, providing an array of new block copolymers.

  12. Cell block one and southeast guard tower, looking from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Cell block one and southeast guard tower, looking from the central guard tower, facing southeast (note view also includes cell block ten (left) and cell block nine (right)) - Eastern State Penitentiary, 2125 Fairmount Avenue, Philadelphia, Philadelphia County, PA

  13. New-onset third-degree atrioventricular block because of autoimmune-induced myositis under treatment with anti-programmed cell death-1 (nivolumab) for metastatic melanoma.

    PubMed

    Behling, Juliane; Kaes, Joachim; Münzel, Thomas; Grabbe, Stephan; Loquai, Carmen

    2017-04-01

    There has been considerable progress in treating malignant melanoma over the last few years. The immune-checkpoint-inhibitors nivolumab and pembrolizumab have been approved by the Food and Drug Administration in 2014 for the therapy of metastatic melanoma. Anti-programmed cell death-1-blocking antibodies are known to cause immune-related adverse events. Physicians should be aware of common and rare side effects and pay attention to new ones. We therefore report a severe and life-threatening side effect of anti-programmed cell death-1 immunotherapy with nivolumab that has not been previously reported: the development of a third-degree atrioventricular block. After a second infusion with nivolumab, our patient developed a troponin I-positive and autoantibody-positive myositis and a few days later a new-onset third-degree atrioventricular block. This is most likely because of an autoimmune-induced myositis with a cardiac impairment in terms of a myocarditis, which led to an impairment of the conduction of cardiac electrical stimuli.

  14. Pain management in total knee arthroplasty by intraoperative local anesthetic application and one-shot femoral block

    PubMed Central

    Sigirci, Aykut

    2017-01-01

    Background: Pain after total knee arthroplasty (TKA) is a big problem in orthopaedic surgery. Although opioids and continuous epidural analgesia remain the major options for the postoperative pain management of TKA, they have some undesirable side effects. Epidural analgesia is technically demanding, and the patient requires close monitoring. Different types of local anesthetic applications can successfully treat TKA pain. Local anesthetics have the advantage of minimizing pain at the source. This study investigates the efficacy of different local anesthetic application methods on early, (1st day) pain control after total knee arthroplasty. Materials and Methods: 200 patients who underwent unilateral TKA surgery under spinal anesthesia were randomly assigned into four different groups (fifty in each group) and were administered pain control by different peri- and postoperative regimens. Group A was the control group wherein no postsurgical analgesia was administered to assess spinal anesthesia efficacy; in Group B, only postsurgical one-shot femoral block was applied; in Group C, intraoperative periarticular local anesthetic was applied; in Group D, a combination of the one-shot femoral block and intraoperative periarticular local anesthetics were applied. Demographic data consisting of age, weight, gender and type of deformity of patients were collected. The data did not differ significantly between the four groups. Results: Group D patients experienced significantly better postoperative pain relief (P < 0.05) and were therefore more relaxed in pain (painless time, VAS score) and knee flexion (degrees) than the other patient groups in the 1st postoperative day followup. Painless time of Group D was 10.5 hours and was better than Group C (6.8 hours), Group B (6.2 hours) and Group A (3.0 hours) (P < 0.05). Group A got the best pain Vas score degrees in the 1st postoperative day which showed the success of combined periarticülar local anesthetic injection and

  15. Pain management in total knee arthroplasty by intraoperative local anesthetic application and one-shot femoral block.

    PubMed

    Sigirci, Aykut

    2017-01-01

    Pain after total knee arthroplasty (TKA) is a big problem in orthopaedic surgery. Although opioids and continuous epidural analgesia remain the major options for the postoperative pain management of TKA, they have some undesirable side effects. Epidural analgesia is technically demanding, and the patient requires close monitoring. Different types of local anesthetic applications can successfully treat TKA pain. Local anesthetics have the advantage of minimizing pain at the source. This study investigates the efficacy of different local anesthetic application methods on early, (1 st day) pain control after total knee arthroplasty. 200 patients who underwent unilateral TKA surgery under spinal anesthesia were randomly assigned into four different groups (fifty in each group) and were administered pain control by different peri- and postoperative regimens. Group A was the control group wherein no postsurgical analgesia was administered to assess spinal anesthesia efficacy; in Group B, only postsurgical one-shot femoral block was applied; in Group C, intraoperative periarticular local anesthetic was applied; in Group D, a combination of the one-shot femoral block and intraoperative periarticular local anesthetics were applied. Demographic data consisting of age, weight, gender and type of deformity of patients were collected. The data did not differ significantly between the four groups. Group D patients experienced significantly better postoperative pain relief ( P < 0.05) and were therefore more relaxed in pain (painless time, VAS score) and knee flexion (degrees) than the other patient groups in the 1 st postoperative day followup. Painless time of Group D was 10.5 hours and was better than Group C (6.8 hours), Group B (6.2 hours) and Group A (3.0 hours) ( P < 0.05). Group A got the best pain Vas score degrees in the 1 st postoperative day which showed the success of combined periarticülar local anesthetic injection and femoral nerve block. The intraoperative

  16. An interdisciplinary study of the estuarine and coastal oceanography of Block Island Sound and adjacent New York coastal waters

    NASA Technical Reports Server (NTRS)

    Yost, E. (Principal Investigator)

    1972-01-01

    The author has identified the following significant results. The synoptic repetitive coverage of the multispectral imagery from the ERTS-1 satellite, when photographically reprocessed using the state-of-the-art techniques, has given indication of spectral differences in Block Island and adjacent New England waters which were heretofore unknown. Of particular interest was the possible detection of relatively small amounts of phytoplankton prior to the occurrence of the red tide in Massachusetts waters. Preparation of spatial and temporal hydrographic charts using ERTS-1 imagery and ground truth analysis will hopefully determine the environmental impact on New York coastal waters.

  17. Parasystole due to re-entry as the possible mechanism of ventricular parasystole with second-degree entrance block.

    PubMed

    Kinoshita, Shinji; Katoh, Takakazu; Yoshida, Hiroshi

    2010-05-01

    In 1974, Kinoshita reported a case of 'irregular parasystole' due to type I second-degree entrance block. Since then, many cases of such 'irregular' parasystole have been reported by us. To explain the mechanism of 'irregular' parasystole, two theories have been suggested, namely, 'electrotonic modulation' by Jalife and Moe, and 'type I second-degree entrance block' by us. On the contrary, in 1960, Kinoshita et al. reported a case of concealed bigeminy for the first time. The electrocardiographic findings in concealed bigeminy have suggested that there are dual re-entrant pathways with markedly long effective refractory periods in the re-entrant pathway. We have suggested that parasystole may be caused by re-entry in such re-entrant pathways. In this article, attempts are made to explain the mechanism of all the electrocardiographic findings in our cases of parasystole by 'parasystole due to re-entry'. Using 24 studies on parasystole and 21 studies on concealed extrasystoles that we have reported over 50 years, as well as three exemplary cases in this article, attempts are made to explain all electrocardiographic findings in parasystole by 'parasystole due to re-entry'. The electrocardiographic findings in our previous clinical cases of parasystole and concealed extrasystoles, as well as exemplary cases and diagrams in the present article, strongly suggest 'parasystole due to re-entry' as the mechanism of ventricular parasystole with second-degree entrance block.

  18. Second-Degree Interatrial Block in Hemodialysis Patients

    PubMed Central

    Enriquez, Andres; D'Amato, Anna; de Luna, Antoni Bayes; Baranchuk, Adrian

    2015-01-01

    Interatrial conduction delays manifest as a prolonged P-wave duration on surface ECG and the term interatrial block (IAB) has been coined. They are usually fixed, but cases of intermittent IAB have been described, suggesting functional conduction block at the Bachmann bundle region. We report 2 cases of patients on chronic hemodialysis therapy presenting with intermittent IAB. PMID:25755895

  19. A new algorithm to find fuzzy Hamilton cycle in a fuzzy network using adjacency matrix and minimum vertex degree.

    PubMed

    Nagoor Gani, A; Latha, S R

    2016-01-01

    A Hamiltonian cycle in a graph is a cycle that visits each node/vertex exactly once. A graph containing a Hamiltonian cycle is called a Hamiltonian graph. There have been several researches to find the number of Hamiltonian cycles of a Hamilton graph. As the number of vertices and edges grow, it becomes very difficult to keep track of all the different ways through which the vertices are connected. Hence, analysis of large graphs can be efficiently done with the assistance of a computer system that interprets graphs as matrices. And, of course, a good and well written algorithm will expedite the analysis even faster. The most convenient way to quickly test whether there is an edge between two vertices is to represent graphs using adjacent matrices. In this paper, a new algorithm is proposed to find fuzzy Hamiltonian cycle using adjacency matrix and the degree of the vertices of a fuzzy graph. A fuzzy graph structure is also modeled to illustrate the proposed algorithms with the selected air network of Indigo airlines.

  20. A case of advanced second-degree atrioventricular block in a ferret secondary to lymphoma

    PubMed Central

    Menicagli, F.; Lanza, A.; Sbrocca, F.; Baldi, A.; Spugnini, E.P.

    2016-01-01

    A female ferret was referred as an emergency for severe respiratory distress symptoms. At presentation, the patient was listlessness, dyspnoeic, and hyper-responsive. The clinical examination evidenced dyspnea with cyanosis, altered cardiac rhythm, and hepatomegaly. Electrocardiography showed an advanced second-degree atrioventricular (AV) block. The liver aspirate was diagnostic for lymphoma. The patient did not respond to supportive therapy and rapidly died. Post-mortem exams confirmed the presence of lymphoma with hepatic involvement. Moreover, a pericardial lymphocytic infiltration and a widespread myocardial nodular localization of lymphoma were evidenced as well. This condition was probably the cause of the cardiac arrhythmia. To the best of our knowledge, ours is the first report of cardiac lymphoma causing heart block in ferrets. PMID:27200273

  1. Reversible second degree atrioventricular block after a severe sickle cell crisis.

    PubMed

    Jaeggi, E; Bolens, M; Friedli, B

    1998-01-01

    Despite the high prevalence of sickle cell disease and trait in the black population and its serious potential for microinfarction, there are only a few reports on acute myocardial damage during vasoocclusive crisis. We report a unique case of transient second degree atrioventricular (A-V) block of Mobitz I and II type during a severe sickle cell crisis. Localized high ventricular septum hypoperfusion demonstrated by a 99mTc-MIBI radionuclide study and reversible echocardiographic wall motion abnormalities in the same area were strong indicators for a local ischemic event in the A-V node and His bundle area, explaining the observed transient conduction abnormalities. The present report draws attention to a potentially lethal complication of sickle cell crisis.

  2. [Reversible first-degree atrioventricular block due to hyperthyroidism].

    PubMed

    Çelebi, Aksüyek Savaş; Amasyalı, Basri

    2017-04-01

    Hyperthyroidism often causes tachyarrhythmia. Reversible atrioventricular block caused by hyperthyroidism is rare occurrence. Presently described is a case of atrioventricular block due to hyperthyroidism and recovery after antithyroid treatment.

  3. The influence of chain rigidity and the degree of sulfonation on the morphology of block copolymers as nano reactor

    NASA Astrophysics Data System (ADS)

    Hong, K.; Zhang, X.

    2005-03-01

    Polyelectrolyte block copolymer was used to form an ordered domain of ionic block as a ``nanoreactor'' due to its ability to bind oppositely charged metal ion, Zn^2+, Fe^2+ etc. The purpose of our research is to investigate the controllability of the size and morphology of domains (inorganic nano particles) by changing backbone stiffness, the charge density and the volume fraction of ionic block. Poly(styrene sulfonate) (PSS), which backbone is flexible, and poly(cyclohexadiene sulfonate) (PCHDS), which backbone is ``semiflexible'', were used as ionic blocks. We synthesized PtBS-PSS and PS-PCHDS with various degree of sulfonation and the volume fraction. Zinc oxide (ZnO) nano particles successfully formed in the ionic domain of microphase separated block copolymers. We used SANS to characterize the morphology of block copolymers and TEM for block copolymer containing ZnO nano particles. Our experimental results show that the chemistry of ``sulfonation'' of block copolymers can be successfully used to synthesize nano composite materials.

  4. Monthly Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2015-01-01

    The basic data provided in these data files are derived from time series of Global, Regional, and National Fossil-Fuel CO2 Emissions (http://cdiac.ess-dive.lbl.gov/trends/emis/overview_2011.html), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signature (del 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  5. ["Habitual" left branch block alternating with 2 "disguised" bracnch block].

    PubMed

    Lévy, S; Jullien, G; Mathieu, P; Mostefa, S; Gérard, R

    1976-10-01

    Two cases of alternating left bundle branch block and "masquerading block" (with left bundle branch morphology in the stnadard leads and right bundle branch block morphology in the precordial leads) were studied by serial tracings and his bundle electrocardiography. In case 1 "the masquerading" block was associated with a first degree AV block related to a prolongation of HV interval. This case is to our knowledge the first cas of alternating bundle branch block in which his bundle activity was recorded in man. In case 2, the patient had atrial fibrilation and His bundle recordings were performed while differents degrees of left bundle branch block were present: The mechanism of the alternation and the concept of "masquerading" block are discussed. It is suggested that this type of block represents a right bundle branch block associated with severe lesions of the "left system".

  6. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude - 2016

    DOE Data Explorer

    Andres, R.J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boden, T.A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Marland, G. [Appalachian State University, Boone, NC (United States)

    2016-01-01

    The monthly, fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  7. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude - 2015

    DOE Data Explorer

    Andres, R.J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boden, T.A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Marland, J. [Appalachian State University, Boone, NC (United States)

    2015-01-01

    The monthly, fossil-fuel CO2 emissions estimates from 1950-2011 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2015), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  8. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude - 2013

    DOE Data Explorer

    Andres, R. J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boden, T.A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Marland, G. [Appalachain State University, Boone, NC (United States)

    1996-01-01

    The monthly, fossil-fuel CO2 emissions estimates from 1950-2010 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2013), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  9. Minimum Description Length Block Finder, a Method to Identify Haplotype Blocks and to Compare the Strength of Block Boundaries

    PubMed Central

    Mannila, H.; Koivisto, M.; Perola, M.; Varilo, T.; Hennah, W.; Ekelund, J.; Lukk, M.; Peltonen, L.; Ukkonen, E.

    2003-01-01

    We describe a new probabilistic method for finding haplotype blocks that is based on the use of the minimum description length (MDL) principle. We give a rigorous definition of the quality of a segmentation of a genomic region into blocks and describe a dynamic programming algorithm for finding the optimal segmentation with respect to this measure. We also describe a method for finding the probability of a block boundary for each pair of adjacent markers: this gives a tool for evaluating the significance of each block boundary. We have applied the method to the published data of Daly and colleagues. The results expose some problems that exist in the current methods for the evaluation of the significance of predicted block boundaries. Our method, MDL block finder, can be used to compare block borders in different sample sets, and we demonstrate this by applying the MDL-based method to define the block structure in chromosomes from population isolates. PMID:12761696

  10. Minimum description length block finder, a method to identify haplotype blocks and to compare the strength of block boundaries.

    PubMed

    Mannila, H; Koivisto, M; Perola, M; Varilo, T; Hennah, W; Ekelund, J; Lukk, M; Peltonen, L; Ukkonen, E

    2003-07-01

    We describe a new probabilistic method for finding haplotype blocks that is based on the use of the minimum description length (MDL) principle. We give a rigorous definition of the quality of a segmentation of a genomic region into blocks and describe a dynamic programming algorithm for finding the optimal segmentation with respect to this measure. We also describe a method for finding the probability of a block boundary for each pair of adjacent markers: this gives a tool for evaluating the significance of each block boundary. We have applied the method to the published data of Daly and colleagues. The results expose some problems that exist in the current methods for the evaluation of the significance of predicted block boundaries. Our method, MDL block finder, can be used to compare block borders in different sample sets, and we demonstrate this by applying the MDL-based method to define the block structure in chromosomes from population isolates.

  11. Observing atmospheric blocking with GPS radio occultation - one decade of measurements

    NASA Astrophysics Data System (ADS)

    Brunner, Lukas; Steiner, Andrea

    2017-04-01

    Atmospheric blocking has received a lot of attention in recent years due to its impact on mid-latitude circulation and subsequently on weather extremes such as cold and warm spells. So far blocking studies have been based mainly on re-analysis data or model output. However, it has been shown that blocking frequency exhibits considerable inter-model spread in current climate models. Here we use one decade (2006 to 2016) of satellite-based observations from GPS radio occultation (RO) to analyze blocking in RO data building on work by Brunner et al. (2016). Daily fields on a 2.5°×2.5° longitude-latitude grid are calculated by applying an adequate gridding strategy to the RO measurements. For blocking detection we use a standard blocking detection algorithm based on 500 hPa geopotential height (GPH) gradients. We investigate vertically resolved atmospheric variables such as GPH, temperature, and water vapor before, during, and after blocking events to increase process understanding. Moreover, utilizing the coverage of the RO data set, we investigate global blocking frequencies. The main blocking regions in the northern and southern hemisphere are identified and the (vertical) atmospheric structure linked to blocking events is compared. Finally, an inter-comparison of results from RO data to different re-analyses, such as ERA-Interim, MERRA 2, and JRA-55, is presented. Brunner, L., A. K. Steiner, B. Scherllin-Pirscher, and M. W. Jury (2016): Exploring atmospheric blocking with GPS radio occultation observations. Atmos. Chem. Phys., 16, 4593-4604, doi:10.5194/acp-16-4593-2016.

  12. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude (V. 2012)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA); Boden, Thomas A. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA); Marland, G. [Appalachian State University, Boone, North Caroline (USA)

    2012-01-01

    The basic data provided in these data files are derived from time series of Global, Regional, and National Fossil-Fuel CO2 Emissions (http://cdiac.ess-dive.lbl.gov/trends/emis/overview_2009.html), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html Q10 for a description why emission totals based upon consumption differ from those based upon production).

  13. Annual Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (V. 2015)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Appalachian State University, Boone, North Carolina (USA)

    2015-01-01

    The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  14. Annual Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree latitude by One Degree Longitude (V. 2013)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Appalachian State University, Boone, North Carolina (USA).

    2013-01-01

    The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  15. Working height, block mass and one- vs. two-handed block handling: the contribution to low back and shoulder loading during masonry work.

    PubMed

    Faber, G S; Kingma, I; Kuijer, P P F M; van der Molen, H F; Hoozemans, M J M; Frings-Dresen, M H W; van Dieën, J H

    2009-09-01

    The goal of this study was to compare the effects of the task variables block mass, working height and one- vs. two-handed block handling on low back and shoulder loading during masonry work. In a mock-up of a masonry work site, nine masonry workers performed one- and two-handed block-lifting and block-placing tasks at varying heights (ranging from floor to shoulder level) with blocks of varying mass (ranging from 6 to 16 kg). Kinematics and ground reaction forces were measured and used in a 3-D linked segment model to calculate low back and shoulder loading. Increasing lifting height appeared to be the most effective way to reduce low back loading. However, working at shoulder level resulted in relatively high shoulder loading. Therefore, it was recommended to organise masonry work in such a way that blocks are handled with the hands at about iliac crest height as much as possible.

  16. Electrocardiographic characteristics of atrioventricular block induced by tilt testing.

    PubMed

    Zyśko, Dorota; Gajek, Jacek; Koźluk, Edward; Mazurek, Walentyna

    2009-02-01

    The electrocardiographic (ECG) characteristics of atrioventricular (AV) block during reflex syncope may be unique due to the presence of hypervagotonia. The aim of the present study was to define the ECG characteristics of the AV block induced by neurocardiogenic reflex provoked by tilt testing (TT). A series of 31 patients with presumed vasovagal syncope and AV block provoked by TT was studied. The duration of PP and PR interval, AV block grade and type, concomitant arrhythmias, and timing of the AV block occurrence were assessed. The AV block occurred at TT termination in 26 patients, in the recovery in 4 patients, and in both periods in 1 patient. Atrioventricular block was preceded by sinus slowing, and sinus rhythm during AV block was slow and instable. Mobitz I, 2:1 second-degree AV block, and advanced second-degree AV block were recognized in 35.5, 48.4, and 67.8% of patients, respectively. Third-degree AV block was diagnosed in 41.9% of patients. Twenty-one patients had at least two AV block forms. The most prevalent concomitant arrhythmia was junctional escape rhythm (61.3%). (i) The occurrence of the AV block during neurocardiogenic reaction induced by TT is always preceded by sinus rhythm slowing and usually by PR interval prolongation. (ii) The AV block provoked by TT usually occurs at TT termination, but may occur even in the recovery period in a supine position. Sometimes the AV block may be present both at TT termination and during the recovery period.

  17. Source character of microseismicity in the San Francisco Bay block, California, and implications for seismic hazard

    USGS Publications Warehouse

    Olson, J.A.; Zoback, M.L.

    1998-01-01

    We examine relocated seismicity within a 30-km-wide crustal block containing San Francisco Bay and bounded by two major right-lateral strike-slip fault systems, the Hayward and San Andreas faults, to determine seismicity distribution, source character, and possible relationship to proposed faults. Well-located low-level seismicity (Md ??? 3.0) has occurred persistently within this block throughout the recording interval (1969 to 1995), with the highest levels of activity occurring along or directly adjacent to (within ???5 km) the bounding faults and falling off toward the long axis of the bay. The total seismic moment release within the interior of the Bay block since 1969 is equivalent to one ML 3.8 earthquake, one to two orders of magnitude lower than activity along and within 5 km of the bounding faults. Focal depths of reliably located events within the Bay block are generally less than 13 km with most seismicity in the depth range of 7 to 12 km, similar to focal depths along both the adjacent portions of the San Andreas and Hayward faults. Focal mechanisms for Md 2 to 3 events within the Bay block mimic focal mechanisms along the adjacent San Andreas fault zone and in the East Bay, suggesting that Bay block is responding to a similar regional stress field. Two potential seismic source zones have been suggested within the Bay block. Our hypocentral depths and focal mechanisms suggest that a proposed subhorizontal detachment fault 15 to 18 km beneath the Bay is not seismically active. Several large-scale linear NW-trending aeromagnetic anomalies within the Bay block were previously suggested to represent large through-going subvertical fault zones. The two largest earthquakes (both Md 3.0) in the Bay block since 1969 occur near two of these large-scale linear aeromagnetic anomalies; both have subvertical nodal planes with right-lateral slip subparallel to the magnetic anomalies, suggesting that structures related to the anomalies may be capable of brittle

  18. Finding Rational Parametric Curves of Relative Degree One or Two

    ERIC Educational Resources Information Center

    Boyles, Dave

    2010-01-01

    A plane algebraic curve, the complete set of solutions to a polynomial equation: f(x, y) = 0, can in many cases be drawn using parametric equations: x = x(t), y = y(t). Using algebra, attempting to parametrize by means of rational functions of t, one discovers quickly that it is not the degree of f but the "relative degree," that describes how…

  19. Monthly Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950 - 2007) (V. 2010)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37831-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37831-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy, and Economics Appalachian State University Boone, NC 28608-2131 USA

    2010-01-01

    The basic data provided in these data files are derived from time series of Global, Regional, and National Fossil-Fuel CO2 Emissions (http://cdiac.ess-dive.lbl.gov/trends/emis/overview_2013.html), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signature (del 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996) for years prior to 1990 and a variable population distribution for later years (Andres et al. 2016). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production). The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http

  20. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950 - 2010) (V.2010)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2010-01-01

    The monthly, fossil-fuel CO2 emissions estimates from 1950-2010 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2013), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  1. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950 - 2006) (V.2009)

    DOE Data Explorer

    Andres, R. J. [.; Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory Oak Ridge, TN (USA).; Boden, Thomas A. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory Oak Ridge, TN (USA).; Marland, Greg [Appalachian State University, Boone, North Carolina (USA)

    2009-01-01

    The basic data provided in these data files are derived from time series of Global, Regional, and National Fossil-Fuel CO2 Emissions (http://cdiac.ess-dive.lbl.gov/trends/emis/overview_2006.html), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  2. Monthly Fossil-Fuel CO2 Emissions: Mass of Emissions Gridded by One Degree Latitude by One Degree Longitude (V. 2011) (1950 - 2010)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA); Boden, Thomas A. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA_; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2011-01-01

    The monthly, fossil-fuel CO2 emissions estimates from 1950-2010 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2013), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  3. Benzodiazepine-associated atrioventricular block.

    PubMed

    Arroyo Plasencia, Anna M; Ballentine, Lynn M; Mowry, James B; Kao, Louise W

    2012-01-01

    Dysrhythmias, although common in overdose situations, are not often seen after benzodiazepine exposures. We report two cases of transient atrioventricular block after benzodiazepine misuse. Case 1 is a 4-year-old boy who was found unresponsive after an ingestion of clonazepam. An electrocardiogram (EKG) performed on emergency department presentation demonstrated first-degree atrioventricular block (PR 206 ms). After flumazenil administration, he developed second-degree atrioventricular block (Mobitz Type 1). EKG abnormalities resolved by morning. Serum clonazepam was 478 ng/mL (laboratory clonazepam reference range, 10-75 ng/mL with a dose of up to 6 mg/day) 5 hours after being found unresponsive. Case 2 is a 23-year-old man who presented to the emergency department after ingesting risperidone, combination hydrocodone/acetaminophen, and alprazolam. On arrival, his EKG demonstrated sinus bradycardia with a PR interval of 182 msec. He subsequently developed second-degree atrioventricular block (Mobitz Type I). Sinus bradycardia with resolution of his atrioventricular block (PR 200 ms) was seen on a third EKG performed 5 hours after presentation. These two patients demonstrated transient first- and second-degree atrioventricular block after benzodiazepine exposure. Benzodiazepines have been shown to alter L-type Ca2+ channel function. This alteration in function may account for the dysrhythmias seen in our patients. Together, these cases serve to remind clinicians of this rare but potentially serious complication associated with benzodiazepine exposure.

  4. Annual Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1751 - 2008) (V. 2011)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center, Oak Ridge National Laboratory, U.S.; Boden, T. A. [Carbon Dioxide Information Analysis Center, Oak Ridge National Laboratory, U.S.; Marland, G. [Carbon Dioxide Information Analysis Center, Oak Ridge National Laboratory, U.S.

    2012-01-01

    The basic data provided in these data files are derived from time series of Global, Regional, and National Fossil-Fuel CO2 Emissions (http://cdiac.ess-dive.lbl.gov/trends/emis/overview_2008.html) and references therein. The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signature (del 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  5. Monthly Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950-2008) (V. 2011)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2011-01-01

    The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  6. Monthly Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950 - 2010) (V. 2013)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2013-01-01

    The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  7. Monthly Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1950 - 2009) (V. 2012)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Boden, T. A. [Carbon Dioxide Information Analysis Center Environmental Sciences Division Oak Ridge National Laboratory Oak Ridge, Tennessee 37830-6290 U.S.A.; Marland, G. [Research Institute for Environment, Energy and Economics Appalachian State University Boone, North Carolina 28608 U.S.A.

    2012-01-01

    The monthly, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1950-2013 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2016), the references therein, and the methodology described in Andres et al. (2011). The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  8. Annual Fossil-Fuel CO2 Emissions: Isomass of Emissions Gridded by One Degree Latitude by One Degree Longitude (1751 - 2009) (V. 2012)

    DOE Data Explorer

    Andres, R. J. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA); Boden, Thomas A. [Carbon Dioxide Information Analysis Center (CDIAC), Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (USA); Marlad, Greg [Appalachian State University, Boone, NC (USA)

    2012-01-01

    The annual, isotopic (δ 13C) fossil-fuel CO2 emissions estimates from 1751-2009 provided in this database are derived from time series of global, regional, and national fossil-fuel CO2 emissions (Boden et al. 2012) and references therein. The data accessible here take these tabular, national, mass-emissions data, multiply them by stable carbon isotopic signatures (δ 13C) as described in Andres et al. (2000), and distribute them spatially on a one degree latitude by one degree longitude grid. The within-country spatial distribution is achieved through a fixed population distribution as reported in Andres et al. (1996). Note that the mass-emissions data used here are based on fossil-fuel consumption estimates as these are more representative of within country emissions than fossil-fuel production estimates (see http://cdiac.ess-dive.lbl.gov/faq.html#Q10 for a description why emission totals based upon consumption differ from those based upon production).

  9. Investigating Mathematics with PentaBlocks.

    ERIC Educational Resources Information Center

    Berman, Sheldon; Plummer, Gary A.; Scheuer, Don

    These classic pattern blocks were introduced in the early 1960s as part of the Elementary Science Study materials developed by the Educational Development Center (EDC). The six classic shapes share one common characteristic: all of the angle measurements are multiplies of 30 degrees. Shapes include the regular triangle, square, and hexagon; the…

  10. Opioid receptors mediate direct predictive fear learning: evidence from one-trial blocking.

    PubMed

    Cole, Sindy; McNally, Gavan P

    2007-04-01

    Pavlovian fear learning depends on predictive error, so that fear learning occurs when the actual outcome of a conditioning trial exceeds the expected outcome. Previous research has shown that opioid receptors, including mu-opioid receptors in the ventrolateral quadrant of the midbrain periaqueductal gray (vlPAG), mediate such predictive fear learning. Four experiments reported here used a within-subject one-trial blocking design to study whether opioid receptors mediate a direct or indirect action of predictive error on Pavlovian association formation. In Stage I, rats were trained to fear conditioned stimulus (CS) A by pairing it with shock. In Stage II, CSA and CSB were co-presented once and co-terminated with shock. Two novel stimuli, CSC and CSD, were also co-presented once and co-terminated with shock in Stage II. The results showed one-trial blocking of fear learning (Experiment 1) as well as one-trial unblocking of fear learning when Stage II training employed a higher intensity footshock than was used in Stage I (Experiment 2). Systemic administrations of the opioid receptor antagonist naloxone (Experiment 3) or intra-vlPAG administrations of the selective mu-opioid receptor antagonist CTAP (Experiment 4) prior to Stage II training prevented one-trial blocking. These results show that opioid receptors mediate the direct actions of predictive error on Pavlovian association formation.

  11. Clinical and electrocardiographic presentations of transient trifascicular block in three cats.

    PubMed

    Oxford, Eva M; Giacomazzi, Flavia B; Moïse, N Sydney; Santilli, Roberto A

    2018-06-01

    This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations. The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. The ECG of cat 3 showed first-degree AV block with concomitant right bundle branch block. The diagnosis of trifascicular block was made when paroxysmal third-degree AV block was documented. All cats recovered with medical management within weeks. Each cat resumed a sinus rhythm. Elevated cardiac troponin I concentrations suggested myocarditis that improved. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Protograph LDPC Codes with Node Degrees at Least 3

    NASA Technical Reports Server (NTRS)

    Divsalar, Dariush; Jones, Christopher

    2006-01-01

    In this paper we present protograph codes with a small number of degree-3 nodes and one high degree node. The iterative decoding threshold for proposed rate 1/2 codes are lower, by about 0.2 dB, than the best known irregular LDPC codes with degree at least 3. The main motivation is to gain linear minimum distance to achieve low error floor. Also to construct rate-compatible protograph-based LDPC codes for fixed block length that simultaneously achieves low iterative decoding threshold and linear minimum distance. We start with a rate 1/2 protograph LDPC code with degree-3 nodes and one high degree node. Higher rate codes are obtained by connecting check nodes with degree-2 non-transmitted nodes. This is equivalent to constraint combining in the protograph. The condition where all constraints are combined corresponds to the highest rate code. This constraint must be connected to nodes of degree at least three for the graph to have linear minimum distance. Thus having node degree at least 3 for rate 1/2 guarantees linear minimum distance property to be preserved for higher rates. Through examples we show that the iterative decoding threshold as low as 0.544 dB can be achieved for small protographs with node degrees at least three. A family of low- to high-rate codes with minimum distance linearly increasing in block size and with capacity-approaching performance thresholds is presented. FPGA simulation results for a few example codes show that the proposed codes perform as predicted.

  13. Light irradiance through novel CAD-CAM block materials and degree of conversion of composite cements.

    PubMed

    Lise, Diogo Pedrollo; Van Ende, Annelies; De Munck, Jan; Yoshihara, Kumiko; Nagaoka, Noriyuki; Cardoso Vieira, Luiz Clovis; Van Meerbeek, Bart

    2018-02-01

    To assess light irradiance (LI) delivered by two light-curing units (LCU's) and to measure the degree of conversion (DC) of three composite cements, when cured through different thicknesses of two novel CAD-CAM block materials. 100-μm-thick films of a dual-curable composite cement (G-CEM LinkAce, GC), a light-curable flowable resin-based composite (RBC) (G-ænial Universal Flo, GC) and a micro-hybrid RBC (G-ænial Posterior, GC) were investigated as luting agents. Two 'polymer-ceramic' CAD-CAM blocks (Cerasmart, GC; Enamic, Vita Zahnfabrik) were sectioned in slabs with different thicknesses (1, 3 and 5mm). LI at the bottom of the specimens was measured using a calibrated spectrometer, while being light-cured through the CAD-CAM block slabs for 40s with a low- (±500mW/cm 2 ) or high- (±1,600mW/cm 2 ) irradiance LCU (n=5). After light-curing, micro-Raman spectra of the composite films were acquired to determine DC at 5min, 10min, 1h and 24h. LI data were statistically analyzed by Kruskal-Wallis followed by post-hoc comparisons, while a linear mixed-effect model was applied for the DC analysis. In addition, the CAD-CAM blocks ultrastructure was characterized upon argon-ion slicing using scanning transmission electron microscopy (STEM). Finally, light transmission (LT) through each CAD-CAM block material was assessed using a spectrophotometer. Curing-light attenuation and DC were significantly influenced by thickness and type of the overlying material. LCU only had a significant effect on DC of the micro-hybrid RBC. DC significantly increased over time for all composite cements. CAD-CAM block structural analysis revealed a relatively small and homogenous filler configuration (mean filler size of 0.2-0.5μm) for Cerasmart, while Enamic contained ceramic grains varying in shape and size (1-10μm), which were interconnected by the polymer-based network. LT was much higher at a wavelength range of 300-800nm for Cerasmart than for Enamic. Light-curable composite cements

  14. Degree counting and Shadow system for Toda system of rank two: One bubbling

    NASA Astrophysics Data System (ADS)

    Lee, Youngae; Lin, Chang-Shou; Wei, Juncheng; Yang, Wen

    2018-04-01

    We initiate the program for computing the Leray-Schauder topological degree for Toda systems of rank two. This program still contains a lot of challenging problems for analysts. As the first step, we prove that if a sequence of solutions (u1k ,u2k) blows up, then one of hje ujk/∫Mhje ujk dvg, j = 1 , 2 tends to a sum of Dirac measures. This is so-called the phenomena of weak concentration. Our purposes in this article are (i) to introduce the shadow system due to the bubbling phenomena when one of parameters ρi crosses 4π and ρj ∉ 4 πN where 1 ≤ i ≠ j ≤ 2; (ii) to show how to calculate the topological degree of Toda systems by computing the topological degree of the general shadow systems; (iii) to calculate the topological degree of the shadow system for one point blow up. We believe that the degree counting formula for the shadow system would be useful in other problems.

  15. The WIYN One Degree Imager - Status and Performance

    NASA Astrophysics Data System (ADS)

    Boroson, Todd A.

    2013-06-01

    A preliminary version of the WIYN One Degree Imager (ODI) has been commissioned and put into scientific operation. ODI was designed to take advantage of the excellent image quality and wide field of view of the WIYN 3.5m telescope. It will do this by covering a one square degree focal plane with orthogonal transfer array (OTA) detectors, which have the capability to correct for image motion during the exposure in regions approximately the size of the isokinetic patch. The partial ODI (pODI) differs from the complete ODI in two ways - only 13 of the 64 OTAs populate the focal plane, and only coherent image motion correction is enabled. However, this implementation has allowed the commissioning of the instrument with all subsystems except the additional detectors in place. The 13 OTAs are configured as a 24 X 24 arcminute “science field”, plus 4 outer OTAs, allowing the sampling of all radii within the one square degree field. pODI is now in use for science observations as we prepare to upgrade the focal plane. The performance of pODI is excellent. Image quality is site seeing limited, and, on good seeing nights, we can achieve images around 0.4 arcsec FWHM over the entire field. The guide signal, from selected regions in the outer OTAs, can be passed to the telescope exclusively, or the high frequency component can be applied as a global shift to the OTAs. We are still in the process of characterizing the gains from this coherent correction, but the detectors perform well in this mode. Data are immediately transferred to an archive at Indiana University, where they are pipeline-processed to remove instrumental signature. The OTA detectors perform adequately in terms of read noise, full well, sensitivity, and dark current. They show 2 anomalies: (1) regions in the circuitry outside the imaging area glow under certain circumstances, and (2) a low level degradation of charge transfer efficiency is present between the imaging area and the serial registers. We have

  16. Learning Non-Adjacent Regularities at Age 0 ; 7

    ERIC Educational Resources Information Center

    Gervain, Judit; Werker, Janet F.

    2013-01-01

    One important mechanism suggested to underlie the acquisition of grammar is rule learning. Indeed, infants aged 0 ; 7 are able to learn rules based on simple identity relations (adjacent repetitions, ABB: "wo fe fe" and non-adjacent repetitions, ABA: "wo fe wo", respectively; Marcus et al., 1999). One unexplored issue is…

  17. Distributed deformation and block rotation in 3D

    NASA Technical Reports Server (NTRS)

    Scotti, Oona; Nur, Amos; Estevez, Raul

    1990-01-01

    The authors address how block rotation and complex distributed deformation in the Earth's shallow crust may be explained within a stationary regional stress field. Distributed deformation is characterized by domains of sub-parallel fault-bounded blocks. In response to the contemporaneous activity of neighboring domains some domains rotate, as suggested by both structural and paleomagnetic evidence. Rotations within domains are achieved through the contemporaneous slip and rotation of the faults and of the blocks they bound. Thus, in regions of distributed deformation, faults must remain active in spite of their poor orientation in the stress field. The authors developed a model that tracks the orientation of blocks and their bounding faults during rotation in a 3D stress field. In the model, the effective stress magnitudes of the principal stresses (sigma sub 1, sigma sub 2, and sigma sub 3) are controlled by the orientation of fault sets in each domain. Therefore, adjacent fault sets with differing orientations may be active and may display differing faulting styles, and a given set of faults may change its style of motion as it rotates within a stationary stress regime. The style of faulting predicted by the model depends on a dimensionless parameter phi = (sigma sub 2 - sigma sub 3)/(sigma sub 1 - sigma sub 3). Thus, the authors present a model for complex distributed deformation and complex offset history requiring neither geographical nor temporal changes in the stress regime. They apply the model to the Western Transverse Range domain of southern California. There, it is mechanically feasible for blocks and faults to have experienced up to 75 degrees of clockwise rotation in a phi = 0.1 strike-slip stress regime. The results of the model suggest that this domain may first have accommodated deformation along preexisting NNE-SSW faults, reactivated as normal faults. After rotation, these same faults became strike-slip in nature.

  18. Needle in the external auditory canal: an unusual complication of inferior alveolar nerve block.

    PubMed

    Ribeiro, Leandro; Ramalho, Sara; Gerós, Sandra; Ferreira, Edite Coimbra; Faria e Almeida, António; Condé, Artur

    2014-06-01

    Inferior alveolar nerve block is used to anesthetize the ipsilateral mandible. The most commonly used technique is one in which the anesthetic is injected directly into the pterygomandibular space, by an intraoral approach. The fracture of the needle, although uncommon, can lead to potentially serious complications. The needle is usually found in the pterygomandibular space, although it can migrate and damage adjacent structures, with variable consequences. The authors report an unusual case of a fractured needle, migrating to the external auditory canal, as a result of an inferior alveolar nerve block. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Phytoparasitic Nematodes Adjacent to Established Strawberry Plantations

    PubMed Central

    Crow, R. V.; MacDonald, D. H.

    1978-01-01

    Plant-nematode populations associated with uncultivated vegetation, adjacent strawberry plants, and alternate crop sites were studied at three locations in Minnesota. At one site (Forest Lake), Paratylenchus projectus, Meloidogyne hapla, and Pratylenchus tenuis were frequently associated with the roots of native vegetation. These nematode species were also present in adjacent strawberry beds. Among alternate crops observed, oats and muskmelon usually supported the fewest nematodes although moderate densities of Xiphinema americanum and P. tenuis were found at one location in plots planted to oats. Pratylenchus tenuis was also found on rye at one location. PMID:19305841

  20. Is right ventricular mid-septal pacing superior to apical pacing in patients with high degree atrio-ventricular block and moderately depressed left ventricular function?

    PubMed

    Chen, Kang; Mao, Ye; Liu, Shao-hua; Wu, Qiong; Luo, Qing-zhi; Pan, Wen-qi; Jin, Qi; Zhang, Ning; Ling, Tian-you; Chen, Ying; Gu, Gang; Shen, Wei-feng; Wu, Li-qun

    2014-06-01

    We are aimed to investigate whether right ventricular mid-septal pacing (RVMSP) is superior to conventional right ventricular apical pacing (RVAP) in improving clinical functional capacity and left ventricular ejection fraction (LVEF) for patients with high-degree atrio-ventricular block and moderately depressed left ventricle (LV) function. Ninety-two patients with high-degree atrio-ventricular block and moderately reduced LVEF (ranging from 35% to 50%) were randomly allocated to RVMSP (n=45) and RVAP (n=47). New York Heart Association (NYHA) functional class, echocardiographic LVEF, and distance during a 6-min walk test (6MWT) were determined at 18 months after pacemaker implantation. Serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured using an enzyme-linked immunosorbent assay (ELISA) kit. Compared with baseline, NYHA functional class remained unchanged at 18 months, distance during 6MWT (485 m vs. 517 m) and LVEF (36.7% vs. 41.8%) were increased, but BNP levels were reduced (2352 pg/ml vs. 710 pg/ml) in the RVMSP group compared with those in the RVAP group, especially in patients with LVEF 35%-40% (for all comparisons, P<0.05). However, clinical function capacity and LV function measurements were not significantly changed in patients with RVAP, despite the pacing measurements being similar in both groups, such as R-wave amplitude and capture threshold. RVMSP provides a better clinical utility, compared with RVAP, in patients with high-degree atrioventricular block and moderately depressed LV function whose LVEF levels ranged from 35% to 40%.

  1. Periodontal tissue reaction to customized nano-hydroxyapatite block scaffold in one-wall intrabony defect: a histologic study in dogs

    PubMed Central

    Lee, Jung-Seok; Park, Weon-Yeong; Cha, Jae-Kook; Jung, Ui-Won; Kim, Chang-Sung; Lee, Yong-Keun

    2012-01-01

    Purpose This study evaluated histologically the tissue responses to and the effects of a customized nano-hydroxyapatite (n-HA) block bone graft on periodontal regeneration in a one-wall periodontal-defect model. Methods A customized block bone for filling in the standardized periodontal defect was fabricated from prefabricated n-HA powders and a polymeric sponge. Bilateral 4×4×5 mm (buccolingual width×mesiodistal width×depth), one-wall, critical-size intrabony periodontal defects were surgically created at the mandibular second and fourth premolars of five Beagle dogs. In each dog, one defect was filled with block-type HA and the other served as a sham-surgery control. The animals were sacrificed following an 8-week healing interval for clinical and histological evaluations. Results Although the sites that received an n-HA block showed minimal bone formation, the n-HA block was maintained within the defect with its original hexahedral shape. In addition, only a limited inflammatory reaction was observed at sites that received an n-HA block, which might have been due to the high stability of the customized block bone. Conclusions In the limitation of this study, customized n-HA block could provide a space for periodontal tissue engineering, with minimal inflammation. PMID:22586523

  2. Periodontal tissue reaction to customized nano-hydroxyapatite block scaffold in one-wall intrabony defect: a histologic study in dogs.

    PubMed

    Lee, Jung-Seok; Park, Weon-Yeong; Cha, Jae-Kook; Jung, Ui-Won; Kim, Chang-Sung; Lee, Yong-Keun; Choi, Seong-Ho

    2012-04-01

    This study evaluated histologically the tissue responses to and the effects of a customized nano-hydroxyapatite (n-HA) block bone graft on periodontal regeneration in a one-wall periodontal-defect model. A customized block bone for filling in the standardized periodontal defect was fabricated from prefabricated n-HA powders and a polymeric sponge. Bilateral 4×4×5 mm (buccolingual width×mesiodistal width×depth), one-wall, critical-size intrabony periodontal defects were surgically created at the mandibular second and fourth premolars of five Beagle dogs. In each dog, one defect was filled with block-type HA and the other served as a sham-surgery control. The animals were sacrificed following an 8-week healing interval for clinical and histological evaluations. Although the sites that received an n-HA block showed minimal bone formation, the n-HA block was maintained within the defect with its original hexahedral shape. In addition, only a limited inflammatory reaction was observed at sites that received an n-HA block, which might have been due to the high stability of the customized block bone. In the limitation of this study, customized n-HA block could provide a space for periodontal tissue engineering, with minimal inflammation.

  3. Cryopreserved embryo transfer: adjacent or non-adjacent to failed fresh long GnRH-agonist protocol IVF cycle.

    PubMed

    Volodarsky-Perel, Alexander; Eldar-Geva, Talia; Holzer, Hananel E G; Schonberger, Oshrat; Reichman, Orna; Gal, Michael

    2017-03-01

    The optimal time to perform cryopreserved embryo transfer (CET) after a failed oocyte retrieval-embryo transfer (OR-ET) cycle is unknown. Similar clinical pregnancy rates were recently reported in immediate and delayed CET, performed after failed fresh OR-ET, in cycles with the gonadotrophin-releasing hormone (GnRH) antagonist protocol. This study compared outcomes of CET performed adjacently (<50 days, n = 67) and non-adjacently (≥50 to 120 days, n = 62) to the last OR-day of cycles with the GnRH agonist down-regulation protocol. Additional inclusion criteria were patients' age 20-38 years, the transfer of only 1-2 cryopreserved embryos, one treatment cycle per patient and artificial preparation for CET. Significantly higher implantation, clinical pregnancy and live birth rates were found in the non-adjacent group than in the adjacent group: 30.5% versus 11.3% (P = 0.001), 41.9% versus 17.9% (P = 0.003) and 32.3% versus 13.4% (P = 0.01), respectively. These results support the postponement of CET after a failed OR-ET for at least one menstrual cycle, when a preceding long GnRH-agonist protocol is used. Copyright © 2016 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  4. Gas block mechanism for water removal in fuel cells

    DOEpatents

    Issacci, Farrokh; Rehg, Timothy J.

    2004-02-03

    The present invention is directed to apparatus and method for cathode-side disposal of water in an electrochemical fuel cell. There is a cathode plate. Within a surface of the plate is a flow field comprised of interdigitated channels. During operation of the fuel cell, cathode gas flows by convection through a gas diffusion layer above the flow field. Positioned at points adjacent to the flow field are one or more porous gas block mediums that have pores sized such that water is sipped off to the outside of the flow field by capillary flow and cathode gas is blocked from flowing through the medium. On the other surface of the plate is a channel in fluid communication with each porous gas block mediums. The method for water disposal in a fuel cell comprises installing the cathode plate assemblies at the cathode sides of the stack of fuel cells and manifolding the single water channel of each of the cathode plate assemblies to the coolant flow that feeds coolant plates in the stack.

  5. Reversible chronic acquired complete atrioventricular block.

    PubMed

    Rakovec, P; Milcinski, G; Voga, G; Korsic, L

    1982-01-01

    The return of atrioventricular conduction is reported in a case after nearly four years of complete acquired heart block. After recovery from atrioventricular block, right bundle branch block persisted, but P-R interval and H-V interval were normal. Three months later a relapse of second degree infranodal atrioventricular block was noted. A short review of similar cases from the literature is given.

  6. Trazodone and Omeprazole Interaction causing Frequent Second-Degree Mobitz Type 1 Atrioventricular (AV) Block (Wenckebach Phenomenon) and Syncope: A Case Report and Literature Review

    PubMed Central

    Akinseye, Oluwaseun A.; Alfishawy, Mostafa; Radparvar, Farshid; Bakshi, Sanjiv

    2015-01-01

    Patient: Male, 54 Final Diagnosis: Trazodone and omeprazole interaction causing second-degree Mobitz type 1 AV block and syncope Symptoms: Syncope Medication: — Clinical Procedure: Trazodone and omeprazole withheld Specialty: Cardiology Objective: Unexpected drug reaction Background: This case report highlights serious cardiovascular adverse effects with a conventional dose of trazodone as a result of its potential interaction with omeprazole. Case Report: A 54-year-old man who was a former smoker, with dyslipidemia, coronary artery disease, and anxiety disorder developed lightheadedness and syncope the morning of admission. He was taking trazodone 50 mg daily, omeprazole 20 mg daily, and simvastatin 20 mg at bedtime. He doubled the dose of trazodone 50 mg on the night prior to presentation to calm his anxiety. An electrocardiogram revealed sinus rhythm at 60 beats per minute and second-degree Mobitz type 1 atrioventricular (AV) block with 5:4 AV conduction. Results of basic metabolic panel, thyroid-stimulating hormone, and chest radiograph were normal. A transthoracic echocardiogram revealed aortic valve sclerosis. We tested for Lyme disease given his history of hunting in the woods 8 months prior to presentation, but the titer was negative. Trazodone and omeprazole were discontinued. By the 3rd day of medication discontinuation, all symptoms had resolved and the frequency of second-degree AV Mobitz type 1 AV block had decreased to once per hour. Conclusions: Due diligence and meticulous attention to detail needs to be exercised to uncover drug interactions as potential causes of lethal and nonlethal patient symptomatology, as in this case of syncope caused by concomitant use of trazodone and a widely prescribed medication, omeprazole. PMID:26017199

  7. Comparison of cervical spine kinematics using a fluoroscopic model for adjacent segment degeneration. Invited submission from the Joint Section on Disorders of the Spine and Peripheral Nerves, March 2007.

    PubMed

    Cheng, Joseph S; Liu, Fei; Komistek, Richard D; Mahfouz, Mohamed R; Sharma, Adrija; Glaser, Diana

    2007-11-01

    In this cervical spine kinematics study the authors evaluate the motions and forces in the normal, degenerative, and fused states to assess how alteration in the cervical motion segment affects adjacent segment degeneration and spondylosis. Fluoroscopic images obtained in 30 individuals (10 in each group with disease at C5-6) undergoing flexion/extension motions were collected. Kinematic data were obtained from the fluoroscopic images and analyzed with an inverse dynamic mathematical model of the cervical spine that was developed for this analysis. During 20 degrees flexion to 15 degrees extension, average relative angles at the adjacent levels of C6-7 and C4-5 in the fused patients were 13.4 degrees and 8.8 degrees versus 3.7 degrees and 4.8 degrees in the healthy individuals. Differences at C3-4 averaged only about 1 degrees. Maximum transverse forces in the fused spines were two times the skull weight at C6-7 and one times the skull weight at C4-5, compared with 0.2 times the skull weight and 0.3 times the skull weight in the healthy individuals. Vertical forces ranged from 1.6 to 2.6 times the skull weight at C6-7 and from 1.2 to 2.5 times the skull weight at C4-5 in the patients who had undergone fusion, and from 1.4 to 3.1 times the skull weight and from 0.9 to 3.3 times the skull weight, respectively, in the volunteers. Adjacent-segment degeneration may occur in patients with fusion due to increased motions and forces at both adjacent levels when compared with healthy individuals in a comparable flexion and extension range.

  8. Investigation of a new thermosensitive block copolymer micelle: hydrolysis, disruption, and release.

    PubMed

    Pelletier, Maxime; Babin, Jérôme; Tremblay, Luc; Zhao, Yue

    2008-11-04

    Thermosensitive polymer micelles are generally obtained with block copolymers in which one block exhibits a lower critical solution temperature in aqueous solution. We investigate a different design that is based on the use of one block bearing a thermally labile side group, whose hydrolysis upon heating shifts the hydrophilic-hydrophobic balance toward the destabilization of block copolymer micelles. Atom transfer radical polymerization was utilized to synthesize a series of diblock copolymers composed of hydrophilic poly(ethylene oxide) (PEO) and hydrophobic poly(2-tetrahydropyranyl methacrylate) (PTHPMA). We show that micelles of PEO-b-PTHPMA in aqueous solution can be destabilized as a result of the thermosensitive hydrolytic cleavage of tetrahydropyranyl (THP) groups that transforms PTHPMA into hydrophilic poly(methacrylic acid). The three related processes occurring in aqueous solution, namely, hydrolytic cleavage of THP, destabilization of micelles, and release of loaded Nile Red (NR), were investigated simultaneously using 1H NMR, dynamic light scattering, and fluorescence spectroscopy, respectively. At 80 degrees C, the results suggest that the three events proceed with a similar kinetics. Although slower than at elevated temperatures, the disruption of PEO-b-PTHPMA micelles can take place at the body temperature (approximately 37 degrees C), and the release kinetics of NR can be adjusted by changing the relative lengths of the two blocks or the pH of the solution.

  9. Geographic patterns of carbon dioxide emissions from fossil-fuel burning, hydraulic cement production, and gas flaring on a one degree by one degree grid cell basis: 1950 to 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brenkert, A.L.; Andres, R.J.; Marland, G.

    1997-03-01

    Data sets of one degree latitude by one degree longitude carbon dioxide (CO{sub 2}) emissions in units of thousand metric tons of carbon (C) per year from anthropogenic sources have been produced for 1950, 1960, 1970, 1980 and 1990. Detailed geographic information on CO{sub 2} emissions can be critical in understanding the pattern of the atmospheric and biospheric response to these emissions. Global, regional and national annual estimates for 1950 through 1992 were published previously. Those national, annual CO{sub 2} emission estimates were based on statistics on fossil-fuel burning, cement manufacturing and gas flaring in oil fields as well asmore » energy production, consumption and trade data, using the methods of Marland and Rotty. The national annual estimates were combined with gridded one-degree data on political units and 1984 human populations to create the new gridded CO{sub 2} emission data sets. The same population distribution was used for each of the years as proxy for the emission distribution within each country. The implied assumption for that procedure was that per capita energy use and fuel mix is uniform over a political unit. The consequence of this first-order procedure is that the spatial changes observed over time are solely due to changes in national energy consumption and nation-based fuel mix. Increases in emissions over time are apparent for most areas.« less

  10. Constructing an optimal facility layout to maximize adjacency as a function of common boundary length

    NASA Astrophysics Data System (ADS)

    Ghassemi Tari, Farhad; Neghabi, Hossein

    2018-03-01

    An effective facility layout implies that departments with high flow are laid adjacent. However, in the case of a very narrow boundary length between the neighbouring departments, the adjacency would actually be useless. In traditional layout design methods, a score is generally assigned independent of the department's boundary length. This may result in a layout design with a restricted material flow. This article proposes a new concept of adjacency in which the department pairs are laid adjacent with a wider path. To apply this concept, a shop with unequal rectangular departments is contemplated and a mathematical programming model with the objective of maximizing the sum of the adjacency degrees is proposed. A computational experiment is conducted to demonstrate the efficiency of the layout design. It is demonstrated that the new concept provides a more efficient and a more realistic layout design.

  11. Variability of adjacency effects in sky reflectance measurements.

    PubMed

    Groetsch, Philipp M M; Gege, Peter; Simis, Stefan G H; Eleveld, Marieke A; Peters, Steef W M

    2017-09-01

    Sky reflectance R sky (λ) is used to correct in situ reflectance measurements in the remote detection of water color. We analyzed the directional and spectral variability in R sky (λ) due to adjacency effects against an atmospheric radiance model. The analysis is based on one year of semi-continuous R sky (λ) observations that were recorded in two azimuth directions. Adjacency effects contributed to R sky (λ) dependence on season and viewing angle and predominantly in the near-infrared (NIR). For our test area, adjacency effects spectrally resembled a generic vegetation spectrum. The adjacency effect was weakly dependent on the magnitude of Rayleigh- and aerosol-scattered radiance. The reflectance differed between viewing directions 5.4±6.3% for adjacency effects and 21.0±19.8% for Rayleigh- and aerosol-scattered R sky (λ) in the NIR. Under which conditions in situ water reflectance observations require dedicated correction for adjacency effects is discussed. We provide an open source implementation of our method to aid identification of such conditions.

  12. BOREAS RSS-10 TOMS Circumpolar One-Degree PAR Images

    NASA Technical Reports Server (NTRS)

    Dye, Dennis G.; Holben, Brent; Nickeson, Jaime (Editor); Hall, Forrest G. (Editor); Smith, David E. (Technical Monitor)

    2000-01-01

    The Boreal Ecosystem-Atmosphere Study (BOREAS) Remote Sensing Science (RSS)-10 team investigated the magnitude of daily, seasonal, and yearly variations of Photosynthetically Active Radiation (PAR) from ground and satellite observations. This data set contains satellite estimates of surface-incident PAR (400-700 nm, MJ/sq m) at one-degree spatial resolution. The spatial coverage is circumpolar from latitudes of 41 to 66 degrees north. The temporal coverage is from May through September for years 1979 through 1989. Eleven-year statistics are also provided: (1) mean, (2) standard deviation, and (3) coefficient of variation for 1979-89. The PAR estimates were derived from the global gridded ultraviolet reflectivity data product (average of 360, 380 nm) from the Nimbus-7 Total Ozone Mapping Spectrometer (TOMS). Image mask data are provided for identifying the boreal forest zone, and ocean/land and snow/ice-covered areas. The data are available as binary image format data files. The PAR data are available from the Earth Observing System Data and Information System (EOSDIS) Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC). The data files are available on a CD-ROM (see document number 20010000884).

  13. Degree-constrained multicast routing for multimedia communications

    NASA Astrophysics Data System (ADS)

    Wang, Yanlin; Sun, Yugeng; Li, Guidan

    2005-02-01

    Multicast services have been increasingly used by many multimedia applications. As one of the key techniques to support multimedia applications, the rational and effective multicast routing algorithms are very important to networks performance. When switch nodes in networks have different multicast capability, multicast routing problem is modeled as the degree-constrained Steiner problem. We presented two heuristic algorithms, named BMSTA and BSPTA, for the degree-constrained case in multimedia communications. Both algorithms are used to generate degree-constrained multicast trees with bandwidth and end to end delay bound. Simulations over random networks were carried out to compare the performance of the two proposed algorithms. Experimental results show that the proposed algorithms have advantages in traffic load balancing, which can avoid link blocking and enhance networks performance efficiently. BMSTA has better ability in finding unsaturated links and (or) unsaturated nodes to generate multicast trees than BSPTA. The performance of BMSTA is affected by the variation of degree constraints.

  14. 2. FIRST AVENUE, PERSPECTIVE VIEW OF WEST SIDE OF BLOCK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. FIRST AVENUE, PERSPECTIVE VIEW OF WEST SIDE OF BLOCK FACE BEGINNING WITH 136 FIRST AVENUE LOOKING NORTH - Towns of Sea Girt, Manasquan & Brielle, Adjacent to State Route 71, south of State Route 38, Sea Girt, Monmouth County, NJ

  15. [Influence of ambient light and adjacent tooth in anterior tooth color measurement].

    PubMed

    Wang, Si-qian; Sean, S Lee; Wu, Zhang; Li, Yiming; Ma, Jian-feng

    2007-10-01

    To investigate the influence of different intensity and directions of ambient light and adjacent tooth in anterior tooth color measurement by using colorimeter. Fiber lite MI-150 was used as ambient illuminant and it irradiated from three or twelve o'clock direction through 45 degrees angle above. The light magnitude 0, 50, 75, 100, 125, 150 W were applied in this experiment. The values of CIE L* a* b* were measured by Minolta Chroma meter CR-321 colorimeter on the center labial surface of ten extracted human maxillary central incisors with or without adjacent teeth, then those data were analyzed statistically by using SPSS 11.5. Neither different intensities nor different directions of ambient light could influence the results of color measurement by using Minolta Chroma meter CR-321 colorimeter, so did the adjacent teeth whether those were exist or not. There is no influence of ambient light and adjacent teeth in the color measurement of anterior teeth under this experiment condition, and Minolta Chroma meter CR-321 colorimeter can be used to measure the color directly aside the chair with light.

  16. An integrated environmental tracer approach to characterizing groundwater circulation in a mountain block

    USGS Publications Warehouse

    Manning, Andrew H.; Solomon, D. Kip

    2005-01-01

    The subsurface transfer of water from a mountain block to an adjacent basin (mountain block recharge (MBR)) is a commonly invoked mechanism of recharge to intermountain basins. However, MBR estimates are highly uncertain. We present an approach to characterize bulk fluid circulation in a mountain block and thus MBR that utilizes environmental tracers from the basin aquifer. Noble gas recharge temperatures, groundwater ages, and temperature data combined with heat and fluid flow modeling are used to identify clearly improbable flow regimes in the southeastern Salt Lake Valley, Utah, and adjacent Wasatch Mountains. The range of possible MBR rates is reduced by 70%. Derived MBR rates (5.5–12.6 × 104 m3 d−1) are on the same order of magnitude as previous large estimates, indicating that significant MBR to intermountain basins is plausible. However, derived rates are 50–100% of the lowest previous estimate, meaning total recharge is probably less than previously thought.

  17. Synthesis of most polyene natural product motifs using just twelve building blocks and one coupling reaction

    PubMed Central

    Woerly, Eric M.; Roy, Jahnabi; Burke, Martin D.

    2014-01-01

    The inherent modularity of polypeptides, oligonucleotides, and oligosaccharides has been harnessed to achieve generalized building block-based synthesis platforms. Importantly, like these other targets, most small molecule natural products are biosynthesized via iterative coupling of bifunctional building blocks. This suggests that many small molecules also possess inherent modularity commensurate with systematic building block-based construction. Supporting this hypothesis, here we report that the polyene motifs found in >75% of all known polyene natural products can be synthesized using just 12 building blocks and one coupling reaction. Using the same general retrosynthetic algorithm and reaction conditions, this platform enabled the synthesis of a wide range of polyene frameworks covering all of this natural product chemical space, and first total syntheses of the polyene natural products asnipyrone B, physarigin A, and neurosporaxanthin β-D-glucopyranoside. Collectively, these results suggest the potential for a more generalized approach for making small molecules in the laboratory. PMID:24848233

  18. 1. FIRST AVENUE, PERSPECTIVE VIEW OF WEST SIDE OF BLOCK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. FIRST AVENUE, PERSPECTIVE VIEW OF WEST SIDE OF BLOCK FACE BEGINNING WITH 156 FIRST AVENUE LOOKING SOUTH, PUBLIC WALK AND OCEANFRONT COTTAGES - Towns of Sea Girt, Manasquan & Brielle, Adjacent to State Route 71, south of State Route 38, Sea Girt, Monmouth County, NJ

  19. Non-crosslinked, amorphous, block copolymer electrolyte for batteries

    DOEpatents

    Mayes, Anne M.; Ceder, Gerbrand; Chiang, Yet-Ming; Sadoway, Donald R.; Aydinol, Mehmet K.; Soo, Philip P.; Jang, Young-Il; Huang, Biying

    2006-04-11

    Solid battery components are provided. A block copolymeric electrolyte is non-crosslinked and non-glassy through the entire range of typical battery service temperatures, that is, through the entire range of at least from about 0.degree. C. to about 70.degree. C. The chains of which the copolymer is made each include at least one ionically-conductive block and at least one second block immiscible with the ionically-conductive block. The chains form an amorphous association and are arranged in an ordered nanostructure including a continuous matrix of amorphous ionically-conductive domains and amorphous second domains that are immiscible with the ionically-conductive domains. A compound is provided that has a formula of Li.sub.xM.sub.yN.sub.zO.sub.2. M and N are each metal atoms or a main group elements, and x, y and z are each numbers from about 0 to about 1. y and z are chosen such that a formal charge on the M.sub.yN.sub.z portion of the compound is (4-x). In certain embodiments, these compounds are used in the cathodes of rechargeable batteries. The present invention also includes methods of predicting the potential utility of metal dichalgogenide compounds for use in lithium intercalation compounds. It also provides methods for processing lithium intercalation oxides with the structure and compositional homogeneity necessary to realize the increased formation energies of said compounds. An article is made of a dimensionally-stable, interpenetrating microstructure of a first phase including a first component and a second phase, immiscible with the first phase, including a second component. The first and second phases define interphase boundaries between them, and at least one particle is positioned between a first phase and a second phase at an interphase boundary. When the first and second phases are electronically-conductive and ionically-conductive polymers, respectively, and the particles are ion host particles, the arrangement is an electrode of a battery.

  20. Diastolic mitral and tricuspid regurgitation by Doppler echocardiography in patients with atrioventricular block: new insight into the mechanism of atrioventricular valve closure.

    PubMed

    Schnittger, I; Appleton, C P; Hatle, L K; Popp, R L

    1988-01-01

    The purpose of this study was to prospectively determine the incidence of diastolic mitral and tricuspid regurgitation in atrioventricular (AV) block using Doppler echocardiography. The temporal relation between mitral and tricuspid diastolic insufficiency and the diastolic murmur recorded in patients with complete heart block was also investigated. Twenty-two consecutive patients with AV block (referred to the Echo-Doppler laboratory for routine clinical studies), aged 18 to 87 years, were enrolled in the study. Eleven patients had third degree AV block and a ventricular-inhibited (VVI) pacemaker, two patients had second degree AV block, seven patients had first degree AV block, one patient had blocked premature atrial complexes and one patient had atrial flutter with 4:1 AV block. Diastolic mitral regurgitation was detected in 20 patients, and diastolic tricuspid regurgitation in 21. A mid-diastolic murmur was detected in all patients except in the three youngest. The murmur occurred before diastolic regurgitation and coincided with peak forward flow through the AV valve after atrial contraction. M-mode mitral valve echocardiograms obtained in nine patients demonstrated near closure of some portions of the mitral valve after atrial contraction. Effective closure of the valve, however, did not occur unless ventricular systole supervened. In conclusion, diastolic mitral and tricuspid regurgitation are almost universally present in patients with AV block and are associated with a diastolic murmur. The murmur coincides with forward AV valve flow. Diastolic regurgitation is silent. Effective AV valve closure is not established until ventricular systole occurs, as demonstrated by M-mode echocardiographic recording of the mitral valve.

  1. Physics Doctorates One Year after Degree: Data from the Follow-up Survey of Degree Recipients from the Classes of 2013 and 2014. Focus On

    ERIC Educational Resources Information Center

    Pold, Jack; Mulvey, Patrick

    2016-01-01

    This report presents trend data on the status of physics PhDs one year after receiving their degree. For the last decade postdoctoral fellowships were the most commonly reported positions taken by physics PhDs in the year after receiving their degree. The type of initial employment for of physics PhDs varied depending on the subfield of their…

  2. The Structure of the Onega Downthrown Block and Adjacent Geological Objects According to the Microseismic Sounding Method

    NASA Astrophysics Data System (ADS)

    Danilov, Konstantin B.

    2017-07-01

    The geological structure of the major part of the Arkhangelsk region in the North-West Russia has been poorly studied. In the present work, the microseismic sounding method was, for the first time, used to carry out a detailed geological-geophysical survey in the region. The particles motion study confirmed the results of mathematical modeling of the smallest imaged heterogeneity and resolution of the method. The microseism stability study allowed to determine the amount of error of the microseismic sounding method which is 1-2 dB. Two geophysical cross sections of the north-eastern and south-western boundaries of the Onega downthrown block were studied. The method was shown to allow obtaining seismic images with a high precision in the horizontal direction at relatively low costs in terms of time and finances. The obtained data provided additional information about the structure of the crust, which was consistent with the known geological and geophysical information for the surveyed area. Based on the data, it was concluded that the main reasons of the dissonance of geological information were most likely the division of the downthrown block into the northern and southern blocks and horizontal displacement of the layer to the North at a depth ranging from 3 to 5 km. It was suggested that the most active tectonic processes, including eruptions of ancient volcanoes, occurred in the northern block. Two benches at the studied downthrown block were allocated at the depths of 5 and 10 km.

  3. Conference room 211, adjacent to commander's quarters, with vault door ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Conference room 211, adjacent to commander's quarters, with vault door at right. Projection area at center is equipped with automatic security drapes. Projection room uses a 45 degree mirror to reflect the image onto the frosted glass screen. Door on far left leads to display area senior battle staff viewing bridge, and the commander's quarters - March Air Force Base, Strategic Air Command, Combat Operations Center, 5220 Riverside Drive, Moreno Valley, Riverside County, CA

  4. Bicomponent Block Copolymers Derived from One or More Random Copolymers as an Alternative Route to Controllable Phase Behavior

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ashraf, Arman R.; Ryan, Justin J.; Satkowski, Michael M.

    Block copolymers have been extensively studied due to their ability to spontaneously self-organize into a wide variety of morphologies that are valuable in energy-, medical- and conservation-related (nano)technologies. While the phase behavior of bicomponent diblock and triblock copolymers is conventionally governed by temperature and individual block masses, we demonstrate that their phase behavior can alternatively be controlled through the use of blocks with random monomer sequencing. Block random copolymers (BRCs), i.e., diblock copolymers wherein one or both blocks is a random copolymer comprised of A and B repeat units, have been synthesized, and their phase behavior, expressed in terms ofmore » the order-disorder transition (ODT), has been investigated. Our results establish that, depending on the block composition contrast and molecular weight, BRCs can microphase-separate. We also report that the predicted ODT can be generated at relatively constant molecular weight and temperature with these new soft materials. This sequence-controlled synthetic strategy is extended to thermoplastic elastomeric triblock copolymers differing in chemistry and possessing a random-copolymer midblock.« less

  5. Characterizing the inverses of block tridiagonal, block Toeplitz matrices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boffi, Nicholas M.; Hill, Judith C.; Reuter, Matthew G.

    2014-12-04

    We consider the inversion of block tridiagonal, block Toeplitz matrices and comment on the behaviour of these inverses as one moves away from the diagonal. Using matrix M bius transformations, we first present an O(1) representation (with respect to the number of block rows and block columns) for the inverse matrix and subsequently use this representation to characterize the inverse matrix. There are four symmetry-distinct cases where the blocks of the inverse matrix (i) decay to zero on both sides of the diagonal, (ii) oscillate on both sides, (iii) decay on one side and oscillate on the other and (iv)more » decay on one side and grow on the other. This characterization exposes the necessary conditions for the inverse matrix to be numerically banded and may also aid in the design of preconditioners and fast algorithms. Finally, we present numerical examples of these matrix types.« less

  6. Incipient microphase separation in short chain perfluoropolyether-block-poly(ethylene oxide) copolymers.

    PubMed

    Chintapalli, Mahati; Timachova, Ksenia; Olson, Kevin R; Banaszak, Michał; Thelen, Jacob L; Mecham, Sue J; DeSimone, Joseph M; Balsara, Nitash P

    2017-06-07

    Incipient microphase separation is observed by wide angle X-ray scattering (WAXS) in short chain multiblock copolymers consisting of perfluoropolyether (PFPE) and poly(ethylene oxide) (PEO) segments. Two PFPE-PEO block copolymers were studied; one with dihydroxyl end groups and one with dimethyl carbonate end groups. Despite having a low degree of polymerization (N ∼ 10), these materials exhibited significant scattering intensity, due to disordered concentration fluctuations between their PFPE-rich and PEO-rich domains. The disordered scattering intensity was fit to a model based on a multicomponent random phase approximation to determine the value of the interaction parameter, χ, and the radius of gyration, R g . Over the temperature range 30-90 °C, the values of χ were determined to be very large (∼2-2.5), indicating a high degree of immiscibility between the PFPE and PEO blocks. In PFPE-PEO, due to the large electron density contrast between the fluorinated and non-fluorinated block and the high value of χ, disordered scattering was detected at intermediate scattering angles, (q ∼ 2 nm -1 ) for relatively small polymer chains. Our ability to detect concentration fluctuations was enabled by both a relatively large value of χ and significant scattering contrast.

  7. Anesthetic efficacy of the intraosseous injection after an inferior alveolar nerve block.

    PubMed

    Dunbar, D; Reader, A; Nist, R; Beck, M; Meyers, W J

    1996-09-01

    The purpose of this study was to determine the contribution of the intraosseous (IO) injection to the inferior alveolar nerve (IAN) block in human first molars. Using a repeated-measures design, 40 subjects randomly received either a combination IAN block + IO injection (on the distal of the first molar) using 2% lidocaine with 1:100,000 epinephrine or an IAN block+mock IO injection (gingival penetration only) at two successive appointments. The first molar and adjacent teeth, and contralateral canine (+/-controls) were blindly tested with an Analytic Technology pulp tester at 2-min cycles for 60 min. An 80 reading was used as the criterion for pulpal anesthesia. One hundred percent of the subjects had lip numbness with the IAN block. For the first molar, anesthetic success, defined as achieving an 80 reading within 15 min and keeping this reading for 60 min, was 42% with the IAN and 90% with the IAN + IO. Anesthetic failure defined as never achieving two 80 readings during the 60 min was 32% with the IAN and 0% with the IAN + IO. The onset of anesthesia was immediate with the IO injection. Eighty percent of the subjects sampled had a subjective increase in heart rate with the IO injection. The IO injection and postinjection questionnaire recorded low pain ratings.

  8. 45Degree view of one (1) arm of the swing span ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45-Degree view of one (1) arm of the swing span bridge in the open position. The view shows the continuous bottom chord of the truss. The vertical post and diagonal web members that frame into this bottom chord are connected with single steel pins at each panel point (or joint). The timber track ties, supporting the track, span from truss to truss bottom chords (16' -0') and are supported thereby. - Bridgeport Swing Span Bridge, Spanning Tennessee River, Bridgeport, Jackson County, AL

  9. Method of forming oriented block copolymer line patterns, block copolymer line patterns formed thereby, and their use to form patterned articles

    DOEpatents

    Russell, Thomas P.; Hong, Sung Woo; Lee, Doug Hyun; Park, Soojin; Xu, Ting

    2015-10-13

    A block copolymer film having a line pattern with a high degree of long-range order is formed by a method that includes forming a block copolymer film on a substrate surface with parallel facets, and annealing the block copolymer film to form an annealed block copolymer film having linear microdomains parallel to the substrate surface and orthogonal to the parallel facets of the substrate. The line-patterned block copolymer films are useful for the fabrication of magnetic storage media, polarizing devices, and arrays of nanowires.

  10. Method of forming oriented block copolymer line patterns, block copolymer line patterns formed thereby, and their use to form patterned articles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Russell, Thomas P.; Hong, Sung Woo; Lee, Dong Hyun

    A block copolymer film having a line pattern with a high degree of long-range order is formed by a method that includes forming a block copolymer film on a substrate surface with parallel facets, and annealing the block copolymer film to form an annealed block copolymer film having linear microdomains parallel to the substrate surface and orthogonal to the parallel facets of the substrate. The line-patterned block copolymer films are useful for the fabrication of magnetic storage media, polarizing devices, and arrays of nanowires.

  11. [Preparation of frozen blocks of fish flesh and its evaluation during storage].

    PubMed

    Rodríguez, L; Bello, R A

    1987-06-01

    Minced fish flesh from shrimp by-catch was used as raw material to prepare four frozen blocks under different conditions, as follows: a) Minced fish flesh washed in cool water for 10 minutes with continuous stirring (water-fish proportion, 3:1). b) Minced fish flesh mixed with sodium tripolyphosphate (TPP) (0.5%), and sodium chloride (1%), respectively. c) Minced fish flesh mixed with 0.5% sodium tripolyphosphate, 1% sodium chloride and 7.5% corn starch, and c) Minced fish flesh without any treatment, which was used as control. Fish blocks were frozen at -40 degrees C and stored at -10 degrees C and -30 degrees C freezing points during a six-month period. Physical, chemical and microbiological tests were performed during the storage period. The results obtained indicate that frozen fish blocks stored at -10 degrees C deteriorate faster than those stored at -30 degrees C. The TPP, sodium chloride and corn starch treatments were not effective in reducing protein denaturation, but they do increase the water retention capacity of the blocks.

  12. Global Population Distribution (1990),Terrestrial Area and Country Name Information on a One by One Degree Grid Cell Basis

    DOE Data Explorer

    Li, Yi-Fan [Canadian Global Emissions Inventory Centre, Downsview, Ontario (Canada); Brenkert, A. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    1996-01-01

    This data base contains gridded (one degree by one degree) information on the world-wide distribution of the population for 1990 and country-specific information on the percentage of the country's population present in each grid cell (Li, 1996a). Secondly, the data base contains the percentage of a country's total area in a grid cell and the country's percentage of the grid cell that is terrestrial (Li, 1996b). Li (1996b) also developed an indicator signifying how many countries are represented in a grid cell and if a grid cell is part of the sea; this indicator is only relevant for the land, countries, and sea-partitioning information of the grid cell. Thirdly, the data base includes the latitude and longitude coordinates of each grid cell; a grid code number, which is a translation of the latitude/longitude value and is used in the Global Emission Inventory Activity (GEIA) data bases; the country or region's name; and the United Nations three-digit country code that represents that name.

  13. Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction.

    PubMed

    Woerly, Eric M; Roy, Jahnabi; Burke, Martin D

    2014-06-01

    The inherent modularity of polypeptides, oligonucleotides and oligosaccharides has been harnessed to achieve generalized synthesis platforms. Importantly, like these other targets, most small-molecule natural products are biosynthesized via iterative coupling of bifunctional building blocks. This suggests that many small molecules also possess inherent modularity commensurate with systematic building block-based construction. Supporting this hypothesis, here we report that the polyene motifs found in >75% of all known polyene natural products can be synthesized using just 12 building blocks and one coupling reaction. Using the same general retrosynthetic algorithm and reaction conditions, this platform enabled both the synthesis of a wide range of polyene frameworks that covered all of this natural-product chemical space and the first total syntheses of the polyene natural products asnipyrone B, physarigin A and neurosporaxanthin b-D-glucopyranoside. Collectively, these results suggest the potential for a more generalized approach to making small molecules in the laboratory.

  14. Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction

    NASA Astrophysics Data System (ADS)

    Woerly, Eric M.; Roy, Jahnabi; Burke, Martin D.

    2014-06-01

    The inherent modularity of polypeptides, oligonucleotides and oligosaccharides has been harnessed to achieve generalized synthesis platforms. Importantly, like these other targets, most small-molecule natural products are biosynthesized via iterative coupling of bifunctional building blocks. This suggests that many small molecules also possess inherent modularity commensurate with systematic building block-based construction. Supporting this hypothesis, here we report that the polyene motifs found in >75% of all known polyene natural products can be synthesized using just 12 building blocks and one coupling reaction. Using the same general retrosynthetic algorithm and reaction conditions, this platform enabled both the synthesis of a wide range of polyene frameworks that covered all of this natural-product chemical space and the first total syntheses of the polyene natural products asnipyrone B, physarigin A and neurosporaxanthin β-D-glucopyranoside. Collectively, these results suggest the potential for a more generalized approach to making small molecules in the laboratory.

  15. Risk of advanced heart block during extradural anaesthesia in patients with right bundle branch block and left anterior hemiblock.

    PubMed

    Coriat, P; Harari, A; Ducardonet, A; Tarot, J P; Viars, P

    1981-05-01

    Electrocardiographic recording by Holter monitoring demonstrated the absence of any modification, however minimal, of the intranodal conduction during surgical procedures under extradural anaesthesia in 20 patients with right bundle branch block (RBBB) and left anterior hemiblock (LAHB) but without symptoms. These data suggest that extradural anaesthesia can be used safely in patients with asymptomatic chronic RBBB and LAHB without prophylactic insertion of pacemakers. However, patients having experienced either syncope or transient Mobitz II second degree AV block are likely to have a trifascicular block and increased risk of advanced heart block during extradural anaesthesia.

  16. Comparison of two-stage thermophilic (68 degrees C/55 degrees C) anaerobic digestion with one-stage thermophilic (55 degrees C) digestion of cattle manure.

    PubMed

    Nielsen, H B; Mladenovska, Z; Westermann, P; Ahring, B K

    2004-05-05

    A two-stage 68 degrees C/55 degrees C anaerobic degradation process for treatment of cattle manure was studied. In batch experiments, an increase of the specific methane yield, ranging from 24% to 56%, was obtained when cattle manure and its fractions (fibers and liquid) were pretreated at 68 degrees C for periods of 36, 108, and 168 h, and subsequently digested at 55 degrees C. In a lab-scale experiment, the performance of a two-stage reactor system, consisting of a digester operating at 68 degrees C with a hydraulic retention time (HRT) of 3 days, connected to a 55 degrees C reactor with 12-day HRT, was compared with a conventional single-stage reactor running at 55 degrees C with 15-days HRT. When an organic loading of 3 g volatile solids (VS) per liter per day was applied, the two-stage setup had a 6% to 8% higher specific methane yield and a 9% more effective VS-removal than the conventional single-stage reactor. The 68 degrees C reactor generated 7% to 9% of the total amount of methane of the two-stage system and maintained a volatile fatty acids (VFA) concentration of 4.0 to 4.4 g acetate per liter. Population size and activity of aceticlastic methanogens, syntrophic bacteria, and hydrolytic/fermentative bacteria were significantly lower in the 68 degrees C reactor than in the 55 degrees C reactors. The density levels of methanogens utilizing H2/CO2 or formate were, however, in the same range for all reactors, although the degradation of these substrates was significantly lower in the 68 degrees C reactor than in the 55 degrees C reactors. Temporal temperature gradient electrophoresis profiles (TTGE) of the 68 degrees C reactor demonstrated a stable bacterial community along with a less divergent community of archaeal species. Copyright 2004 Wiley Periodicals, Inc.

  17. Local adjacency metric dimension of sun graph and stacked book graph

    NASA Astrophysics Data System (ADS)

    Yulisda Badri, Alifiah; Darmaji

    2018-03-01

    A graph is a mathematical system consisting of a non-empty set of nodes and a set of empty sides. One of the topics to be studied in graph theory is the metric dimension. Application in the metric dimension is the navigation robot system on a path. Robot moves from one vertex to another vertex in the field by minimizing the errors that occur in translating the instructions (code) obtained from the vertices of that location. To move the robot must give different instructions (code). In order for the robot to move efficiently, the robot must be fast to translate the code of the nodes of the location it passes. so that the location vertex has a minimum distance. However, if the robot must move with the vertex location on a very large field, so the robot can not detect because the distance is too far.[6] In this case, the robot can determine its position by utilizing location vertices based on adjacency. The problem is to find the minimum cardinality of the required location vertex, and where to put, so that the robot can determine its location. The solution to this problem is the dimension of adjacency metric and adjacency metric bases. Rodrguez-Velzquez and Fernau combine the adjacency metric dimensions with local metric dimensions, thus becoming the local adjacency metric dimension. In the local adjacency metric dimension each vertex in the graph may have the same adjacency representation as the terms of the vertices. To obtain the local metric dimension of values in the graph of the Sun and the stacked book graph is used the construction method by considering the representation of each adjacent vertex of the graph.

  18. A Perron-Frobenius theory for block matrices associated to a multiplex network

    NASA Astrophysics Data System (ADS)

    Romance, Miguel; Solá, Luis; Flores, Julio; García, Esther; García del Amo, Alejandro; Criado, Regino

    2015-03-01

    The uniqueness of the Perron vector of a nonnegative block matrix associated to a multiplex network is discussed. The conclusions come from the relationships between the irreducibility of some nonnegative block matrix associated to a multiplex network and the irreducibility of the corresponding matrices to each layer as well as the irreducibility of the adjacency matrix of the projection network. In addition the computation of that Perron vector in terms of the Perron vectors of the blocks is also addressed. Finally we present the precise relations that allow to express the Perron eigenvector of the multiplex network in terms of the Perron eigenvectors of its layers.

  19. Nonalcoholic fatty liver disease is associated with an increased risk of heart block in hospitalized patients with type 2 diabetes mellitus.

    PubMed

    Mantovani, Alessandro; Rigolon, Riccardo; Pichiri, Isabella; Bonapace, Stefano; Morani, Giovanni; Zoppini, Giacomo; Bonora, Enzo; Targher, Giovanni

    2017-01-01

    Recent studies suggested that nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiac tachyarrhythmias (mainly atrial fibrillation) in patients with and without type 2 diabetes mellitus. The aim of this study was to examine whether an association also exists between NAFLD and heart block. We have retrospectively evaluated a hospital-based cohort of 751 patients with type 2 diabetes discharged from our Division of Diabetes and Endocrinology during years 2007-2014. Standard electrocardiograms were performed on all patients. Diagnosis of NAFLD was based on ultrasonography, whereas the severity of advanced hepatic fibrosis was based on the fibrosis (FIB)-4 score and other non-invasive fibrosis markers. Overall, 524 (69.8%) patients had NAFLD and 202 (26.9%) had heart block (defined as at least one block among first-degree atrio-ventricular block, second-degree block, third-degree block, left bundle branch block, right bundle branch block, left anterior hemi-block or left posterior hemi-block) on electrocardiograms. Patients with NAFLD had a remarkably higher prevalence of any persistent heart block than those without NAFLD (31.3% vs. 16.7%, p<0.001); this prevalence was particularly increased among those with higher FIB-4 score. NAFLD was associated with a threefold increased risk of prevalent heart block (adjusted-odds ratio 3.04, 95% CI 1.81-5.10), independently of age, sex, hypertension, prior ischemic heart disease, hemoglobin A1c, microvascular complication status, use of medications and other potentially confounding factors. In conclusion, this is the largest cross-sectional study to show that NAFLD and its severity are independently associated with an increased risk of prevalent heart block in hospitalized patients with type 2 diabetes.

  20. Sedimentary records of the Yangtze Block (South China) and their correlation with equivalent Neoproterozoic sequences on adjacent continents

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Zhou, Mei-Fu

    2012-07-01

    The Neoproterozoic Danzhou Group, composed of siliciclastic sedimentary rocks interbedded with minor carbonate and volcanic rocks in the southeastern Yangtze Block, South China, is thought to be related to the breakup of Rodinia. Detrital zircon ages constrain the deposition of the Danzhou Group at ~ 770 Ma and ~ 730 Ma. The Danzhou Group contains dominant Neoproterozoic detrital zircon grains (~ 740-900 Ma) with two major age groups at ~ 740-790 Ma and ~ 810-830 Ma, suggesting the detritus was largely sourced from the widely distributed Neoproterozoic igneous plutons within the Yangtze Block. The sedimentary rocks from the lower Danzhou Group, including sandstones, siltstone and pelitic rocks, have UCC-like chemical signatures, representing mixed products of primary sources. The upper Danzhou Group received more recycled materials because the rocks have relatively higher Zr/Sc ratios, Hf contents and a greater influx of Pre-Neoproterozoic zircons. All of the rocks have high La/Sc, low Sc/Th and Co/Th ratios, consistent with sources dominantly composed of granitic to dioritic end-members from the western and northwestern Yangtze Block. Chemical compositions do not support significant contributions of mafic components. Most Neoproterozoic zircons have positive ɛHf(t) (0-17) indicative of sediments derived mainly from the western and northwestern Yangtze Block. The uni-modal Neoproterozoic zircons and felsic igneous source rocks for the Danzhou Group suggest that the Yangtze Block was an independent continent in the peripheral part of Rodinia.

  1. Is there a prognostic relevance of electrophysiological studies in bundle branch block patients?

    PubMed

    Bogossian, Harilaos; Frommeyer, Gerrit; Göbbert, Kornelius; Hasan, Fuad; Nguyen, Quy Suu; Ninios, Ilias; Mijic, Dejan; Bandorski, Dirk; Hoeltgen, Reinhard; Seyfarth, Melchior; Lemke, Bernd; Eckardt, Lars; Zarse, Markus

    2017-08-01

    The present European guidelines suggest a diagnostic electrophysiological (EP) study to determine indication for cardiac pacing in patients with bundle branch block and unexplained syncope. We evaluated the prognostic relevance of an EP study for mortality and the development of permanent complete atrioventricular (AV) block in patients with symptomatic bifascicular block and first-degree AV block. The HV interval is a poor prognostic marker to predict the development of permanent AV block in patients with symptomatic bifascicular block (BFB) and AV block I°. Thirty consecutive patients (mean age, 74.8 ± 8.6 years; 25 males) with symptomatic BFB and first-degree AV block underwent an EP study before device implantation, according to current guidelines. For 53 ± 31 months, patients underwent yearly follow-up screening for syncope or higher-degree AV block. Thirty patients presented with prolonged HV interval during the EP study (mean, 82.2 ± 20.1 ms; range, 57-142 ms), classified into 3 groups: group 1, <70 ms (mean, 62 ± 4 ms; range, 57-67 ms; n = 7), group 2, >70 to ≤100 ms (mean, 80 ± 8 ms; range, 70-97 ms; n = 18), and group 3, >100 ms (mean, 119 ± 14 ms; range, 107-142 ms; n = 5). According to the guidelines, patients in groups 2 and 3 received a pacemaker. The length of the HV interval was not associated with the later development of third-degree AV block or with increased mortality. Our present study suggests that an indication for pacemaker implantation based solely on a diagnostic EP study with prolongation of the HV interval is not justified. © 2017 Wiley Periodicals, Inc.

  2. Catheter ablation as a treatment of atrioventricular block.

    PubMed

    Tuohy, Stephen; Saliba, Walid; Pai, Manjunath; Tchou, Patrick

    2018-01-01

    Symptomatic second-degree atrioventricular (AV) block is typically treated by implantation of a pacemaker. An otherwise healthy AV conduction system can nevertheless develop AV block due to interference from junctional extrasystoles. When present with a high burden, these can produce debilitating symptoms from AV block despite an underlying normal AV node and His-Purkinje system properties. The purpose of this study was to describe a catheter ablation approach for alleviating symptomatic AV block due to a ventricular nodal pathway interfering with AV conduction. Common clinical monitoring techniques such as Holter and event recorders were used. Standard electrophysiological study techniques using multipolar recording and ablation catheters were utilized during procedures. A 55-year-old woman presented with highly symptomatic, high-burden second-degree AV block due to concealed and manifest junctional premature beats. Electrophysiological characteristics indicated interference of AV conduction due to a concealed ventricular nodal pathway as the cause of the AV block. The patient's AV nodal and His-Purkinje system conduction characteristics were otherwise normal. Radiofrequency catheter ablation of the pathway was successful in restoring normal AV conduction and eliminating her clinical symptoms. Pathways inserting into the AV junction can interfere with AV conduction. When present at a high burden, this type of AV block can be highly symptomatic. Catheter ablation techniques can be used to alleviate this type of AV block and restore normal AV conduction. Copyright © 2017 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  3. Changes, Challenges, and Opportunities for Student Services at One Baccalaureate Degree-Granting Community College

    ERIC Educational Resources Information Center

    Martinez, Edna

    2018-01-01

    Objective: The objective of this study was to explore organizational changes within the area of student services at one baccalaureate degree-granting community college. Method: Data were collected via in-depth semistructured interviews with faculty and administrators, observations, and organizational documents. Results: Analysis revealed extensive…

  4. Oligosaccharide/silicon-containing block copolymers with 5 nm features for lithographic applications.

    PubMed

    Cushen, Julia D; Otsuka, Issei; Bates, Christopher M; Halila, Sami; Fort, Sébastien; Rochas, Cyrille; Easley, Jeffrey A; Rausch, Erica L; Thio, Anthony; Borsali, Redouane; Willson, C Grant; Ellison, Christopher J

    2012-04-24

    Block copolymers demonstrate potential for use in next-generation lithography due to their ability to self-assemble into well-ordered periodic arrays on the 3-100 nm length scale. The successful lithographic application of block copolymers relies on three critical conditions being met: high Flory-Huggins interaction parameters (χ), which enable formation of <10 nm features, etch selectivity between blocks for facile pattern transfer, and thin film self-assembly control. The present paper describes the synthesis and self-assembly of block copolymers composed of naturally derived oligosaccharides coupled to a silicon-containing polystyrene derivative synthesized by activators regenerated by electron transfer atom transfer radical polymerization. The block copolymers have a large χ and a low degree of polymerization (N) enabling formation of 5 nm feature diameters, incorporate silicon in one block for oxygen reactive ion etch contrast, and exhibit bulk and thin film self-assembly of hexagonally packed cylinders facilitated by a combination of spin coating and solvent annealing techniques. As observed by small angle X-ray scattering and atomic force microscopy, these materials exhibit some of the smallest block copolymer features in the bulk and in thin films reported to date.

  5. Heat transfer distributions induced by elevon deflections on swept wings and adjacent surfaces at Mach 6

    NASA Technical Reports Server (NTRS)

    Johnson, C. B.; Kaufman, L. G., II

    1978-01-01

    Surface heat transfer distributions are presented for swept wing semispan models having trailing edge elevon ramp angles of 0, 10, 20, and 30 degrees. The wing sweepback angles are 0, 50, and 70 degrees. The models have attachable cylindrical and flat plate center bodies and various attachable wing-tip fins. The data, obtained for a 0 degree angle of attack, a free stream Mach number of 6, and a wing root chord Reynolds number of about 17,000,000, reveal considerably larger regions of elevon induced thermal loads on adjacent surfaces than would be suggested by fully attached flow analyses.

  6. Size cues and the adjacency principle.

    DOT National Transportation Integrated Search

    1963-11-01

    The purpose of the present study was to apply the adjacency principle to the perception of relative depth from size cues. In agreement with the adjacency principle, it was found that the size cue between adjacent objects was more effective than the s...

  7. Fault locking, block rotation and crustal deformation in the Pacific Northwest

    USGS Publications Warehouse

    McCaffrey, R.; Qamar, A.I.; King, R.W.; Wells, R.; Khazaradze, G.; Williams, C.A.; Stevens, C.W.; Vollick, J.J.; Zwick, P.C.

    2007-01-01

    We interpret Global Positioning System (GPS) measurements in the northwestern United States and adjacent parts of western Canada to describe relative motions of crustal blocks, locking on faults and permanent deformation associated with convergence between the Juan de Fuca and North American plates. To estimate angular velocities of the oceanic Juan de Fuca and Explorer plates and several continental crustal blocks, we invert the GPS velocities together with seafloor spreading rates, earthquake slip vector azimuths and fault slip azimuths and rates. We also determine the degree to which faults are either creeping aseismically or, alternatively, locked on the block-bounding faults. The Cascadia subduction thrust is locked mainly offshore, except in central Oregon, where locking extends inland. Most of Oregon and southwest Washington rotate clockwise relative to North America at rates of 0.4-1.0?? Myr-1. No shear or extension along the Cascades volcanic arc has occurred at the mm/yr level during the past decade, suggesting that the shear deformation extending northward from the Walker Lane and eastern California shear zone south of Oregon is largely accommodated by block rotation in Oregon. The general agreement of vertical axis rotation rates derived from GPS velocities with those estimated from palaeomagnetic declination anomalies suggests that the rotations have been relatively steady for 10-15 Ma. Additional permanent dextral shear is indicated within the Oregon Coast Range near the coast. Block rotations in the Pacific Northwest do not result in net westward flux of crustal material - the crust is simply spinning and not escaping. On Vancouver Island, where the convergence obliquity is less than in Oregon and Washington, the contractional strain at the coast is more aligned with Juan de Fuca-North America motion. GPS velocities are fit significantly better when Vancouver Island and the southern Coast Mountains move relative to North America in a block

  8. Pressure distributions induced by elevon deflections on swept wings and adjacent end-plate surfaces at Mach 6

    NASA Technical Reports Server (NTRS)

    Kaufman, L. G., II; Johnson, C. B.

    1977-01-01

    Surface pressure distributions are presented for regions where three-dimensional separated flow effects are prominent on swept-wing-elevon-end-plate models of 0 degree, 50 degree, and 70 degree sweepback, and with 0 degree, 10 degree, 20 degree, and 30 degree elevon deflections. Surface-oil-flow photographs and pressure distributions on the flat-plate wing, elevon, and end-plate surfaces are presented for numerous geometric variations, including various spacings between the elevon and the end plate, with and without a tip fin. The data, for a free-stream Mach number of 6 and a wing-root-chord Reynolds number of 20 x 10 to the sixth power, reveal considerably larger regions of elevon induced loads on the adjacent end-plate surface than would be anticipated by using inviscid flow analyses.

  9. Multi-purpose wind tunnel reaction control model block

    NASA Technical Reports Server (NTRS)

    Dresser, H. S.; Daileda, J. J. (Inventor)

    1978-01-01

    A reaction control system nozzle block is provided for testing the response characteristics of space vehicles to a variety of reaction control thruster configurations. A pressurized air system is connected with the supply lines which lead to the individual jet nozzles. Each supply line terminates in a compact cylindrical plenum volume, axially perpendicular and adjacent to the throat of the jet nozzle. The volume of the cylindrical plenum is sized to provide uniform thrust characteristics from each jet nozzle irrespective of the angle of approach of the supply line to the plenum. Each supply line may be plugged or capped to stop the air supply to selected jet nozzles, thereby enabling a variety of nozzle configurations to be obtained from a single model nozzle block.

  10. Sealed Battery Block Provided With A Cooling System

    DOEpatents

    Verhoog, Roelof; Barbotin, Jean-Loup

    1999-11-16

    The present invention relates to a sealed battery block operating at a pressure of at least 1 bar relative, the battery including a container made of a plastics material and made up of a lid and of a case subdivided into wells by at least one partition, said battery being provided with a cooling system including two cheek plates made of a plastics material and co-operating with the outside faces of respective ones of two opposite walls of said case, each cheek plate co-operating with the corresponding wall to define a compartment provided with a plurality of ribs forming baffles for fluid flow purposes, and with an inlet orifice and an outlet orifice for the fluid, said battery being characterized in that each of said ribs extends in a direction that forms an angle relative to the plane of said partition lying in the range 60.degree. to 90.degree..

  11. Spectra of Adjacency Matrices in Networks of Extreme Introverts and Extroverts

    NASA Astrophysics Data System (ADS)

    Bassler, Kevin E.; Ezzatabadipour, Mohammadmehdi; Zia, R. K. P.

    Many interesting properties were discovered in recent studies of preferred degree networks, suitable for describing social behavior of individuals who tend to prefer a certain number of contacts. In an extreme version (coined the XIE model), introverts always cut links while extroverts always add them. While the intra-group links are static, the cross-links are dynamic and lead to an ensemble of bipartite graphs, with extraordinary correlations between elements of the incidence matrix: nij In the steady state, this system can be regarded as one in thermal equilibrium with long-ranged interactions between the nij's, and displays an extreme Thouless effect. Here, we report simulation studies of a different perspective of networks, namely, the spectra associated with this ensemble of adjacency matrices {aij } . As a baseline, we first consider the spectra associated with a simple random (Erdős-Rényi) ensemble of bipartite graphs, where simulation results can be understood analytically. Work supported by the NSF through Grant DMR-1507371.

  12. Block QCA Fault-Tolerant Logic Gates

    NASA Technical Reports Server (NTRS)

    Firjany, Amir; Toomarian, Nikzad; Modarres, Katayoon

    2003-01-01

    Suitably patterned arrays (blocks) of quantum-dot cellular automata (QCA) have been proposed as fault-tolerant universal logic gates. These block QCA gates could be used to realize the potential of QCA for further miniaturization, reduction of power consumption, increase in switching speed, and increased degree of integration of very-large-scale integrated (VLSI) electronic circuits. The limitations of conventional VLSI circuitry, the basic principle of operation of QCA, and the potential advantages of QCA-based VLSI circuitry were described in several NASA Tech Briefs articles, namely Implementing Permutation Matrices by Use of Quantum Dots (NPO-20801), Vol. 25, No. 10 (October 2001), page 42; Compact Interconnection Networks Based on Quantum Dots (NPO-20855) Vol. 27, No. 1 (January 2003), page 32; Bit-Serial Adder Based on Quantum Dots (NPO-20869), Vol. 27, No. 1 (January 2003), page 35; and Hybrid VLSI/QCA Architecture for Computing FFTs (NPO-20923), which follows this article. To recapitulate the principle of operation (greatly oversimplified because of the limitation on space available for this article): A quantum-dot cellular automata contains four quantum dots positioned at or between the corners of a square cell. The cell contains two extra mobile electrons that can tunnel (in the quantummechanical sense) between neighboring dots within the cell. The Coulomb repulsion between the two electrons tends to make them occupy antipodal dots in the cell. For an isolated cell, there are two energetically equivalent arrangements (denoted polarization states) of the extra electrons. The cell polarization is used to encode binary information. Because the polarization of a nonisolated cell depends on Coulomb-repulsion interactions with neighboring cells, universal logic gates and binary wires could be constructed, in principle, by arraying QCA of suitable design in suitable patterns. Heretofore, researchers have recognized two major obstacles to realization of QCA

  13. 46 CFR 148.445 - Adjacent spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Adjacent spaces. 148.445 Section 148.445 Shipping COAST... THAT REQUIRE SPECIAL HANDLING Additional Special Requirements § 148.445 Adjacent spaces. When... following requirements must be met: (a) Each space adjacent to a cargo hold must be ventilated by natural...

  14. 46 CFR 148.445 - Adjacent spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Adjacent spaces. 148.445 Section 148.445 Shipping COAST... THAT REQUIRE SPECIAL HANDLING Additional Special Requirements § 148.445 Adjacent spaces. When... following requirements must be met: (a) Each space adjacent to a cargo hold must be ventilated by natural...

  15. 46 CFR 148.445 - Adjacent spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Adjacent spaces. 148.445 Section 148.445 Shipping COAST... THAT REQUIRE SPECIAL HANDLING Additional Special Requirements § 148.445 Adjacent spaces. When... following requirements must be met: (a) Each space adjacent to a cargo hold must be ventilated by natural...

  16. 46 CFR 148.445 - Adjacent spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Adjacent spaces. 148.445 Section 148.445 Shipping COAST... THAT REQUIRE SPECIAL HANDLING Additional Special Requirements § 148.445 Adjacent spaces. When... following requirements must be met: (a) Each space adjacent to a cargo hold must be ventilated by natural...

  17. Porous block nanofiber composite filters

    DOEpatents

    Ginley, David S.; Curtis, Calvin J.; Miedaner, Alexander; Weiss, Alan J.; Paddock, Arnold

    2016-08-09

    Porous block nano-fiber composite (110), a filtration system (10) and methods of using the same are disclosed. An exemplary porous block nano-fiber composite (110) includes a porous block (100) having one or more pores (200). The porous block nano-fiber composite (110) also includes a plurality of inorganic nano-fibers (211) formed within at least one of the pores (200).

  18. Hollow Block Copolymer Nanoparticles through a Spontaneous One-Step Structural Reorganization

    PubMed Central

    Petzetakis, Nikos; Robin, Mathew P.; Patterson, Joseph P.; Kelley, Elizabeth G.; Cotanda, Pepa; Bomans, Paul H. H.; Sommerdijk, Nico A. J. M.; Dove, Andrew P.; Epps, Thomas H.; O'Reilly, Rachel K.

    2013-01-01

    The spontaneous one-step synthesis of hollow nanocages and nanotubes from spherical and cylindrical micelles based on poly(acrylic acid)-b-polylactide (P(AA)-b-P(LA)) block copolymers (BCPs) has been achieved. This structural reorganization, which occurs simply upon drying of the samples, was elucidated by transmission electron microscopy (TEM) and atomic force microscopy (AFM). We show that it was necessary to use stain-free imaging to examine these nanoscale assemblies, as the hollow nature of the particles was obscured by application of a heavy metal stain. Additionally, the internal topology of the P(AA)-b-P(LA) particles could be tuned by manipulating the drying conditions to give solid or compartmentalized structures. Upon re-suspension, these reorganized nanoparticles retain their hollow structure and can be display significantly enhanced loading of a hydrophobic dye compared to the original cylinders. PMID:23391297

  19. PID position regulation in one-degree-of-freedom Euler-Lagrange systems actuated by a PMSM

    NASA Astrophysics Data System (ADS)

    Verastegui-Galván, J.; Hernández-Guzmán, V. M.; Orrante-Sakanassi, J.

    2018-02-01

    This paper is concerned with position regulation in one-degree-of-freedom Euler-Lagrange Systems. We consider that the mechanical subsystem is actuated by a permanent magnet synchronous motor (PMSM). Our proposal consists of a Proportional-Integral-Derivative (PID) controller for the mechanical subsystem and a slight variation of field oriented control for the PMSM. We take into account the motor electric dynamics during the stability analysis. We present, for the first time, a global asymptotic stability proof for such a control scheme without requiring the mechanical subsystem to naturally possess viscous friction. Finally, as a corollary of our main result we prove global asymptotic stability for output feedback PID regulation of one-degree-of-freedom Euler-Lagrange systems when generated torque is considered as the system input, i.e. when the electric dynamics of PMSM's is not taken into account.

  20. Block Tectonic Motion on Venus

    NASA Astrophysics Data System (ADS)

    Byrne, P. K.; Ghail, R.; Sengor, A. M. C.; Klimczak, C.; Solomon, S. C.

    2017-12-01

    Despite close similarities in mass and bulk composition to Earth, Venus apparently shows no evidence for Earth-like plate tectonics, except perhaps for limited plume-induced subduction. We use Magellan radar data to survey numerous examples of low-lying areas infilled with plains lavas and delimited by networks of narrow belts of substantial tectonic deformation; such sites include those at Lavinia and Llorona Planitiæ and to the north of Helen Planitia. This deformation is locally extensional or shortening in style but very often also includes structures that denote substantial lateral motion. Cross-cutting relations suggest that this motion occurred both before and after the lavas were emplaced. Together, these observations imply that many of the belt-bounded areas have acted as relatively rigid blocks that experienced considerable horizontal movement relative to each other, in a manner similar to blocks that constitute parts of the Terran continental lithosphere. On Earth, continental deformation is enabled by the low strength of the lower crust and/or upper mantle. On Venus, the shallow brittle-ductile transition (BDT), a result of the planet's elevated surface temperature, likely acts in a similar way to decouple the upper and lower crust. Subcrustal lid rejuvenation, a recently proposed mechanism for renewal of the mantle portion of Venus' stagnant lithospheric lid through thinning and recycling, could drive the horizontal movement of these rigid blocks. It may be, then, that the blocks move as continental blocks do on Earth, with mantle motion transferred to the surface and manifest as narrow zones of tectonic deformation akin to, for example, the Tian Shan and Altin Tagh ranges that bound the Tarim Basin in northwestern China. The shallow BDT on Venus precludes the blocks from subducting, and so their fate is to shorten, lengthen, or retain their geometry at the expense of adjacent blocks. We suggest that this behavior is analogous to plate

  1. The use of non-invasive fetal electrocardiography in diagnosing second-degree fetal atrioventricular block.

    PubMed

    Lakhno, Igor; Behar, Joachim A; Oster, Julien; Shulgin, Vyacheslav; Ostras, Oleksii; Andreotti, Fernando

    2017-01-01

    Complete atrioventricular block in fetuses is known to be mostly associated with autoimmune disease and can be irreversible if no steroids treatment is provided. Conventional methods used in clinical practice for diagnosing fetal arrhythmia are limited since they do not reflect the primary electrophysiological conduction processes that take place in the myocardium. The non-invasive fetal electrocardiogram has the potential to better support fetal arrhythmias diagnosis through the continuous analysis of the beat to beat variation of the fetal heart rate and morphological analysis of the PQRST complex. We present two retrospective case reports on which atrioventricular block diagnosis could have been supported by the non-invasive fetal electrocardiogram. The two cases comprised a 22-year-old pregnant woman with the gestational age of 31 weeks and a 25-year-old pregnant woman with the gestational age of 41 weeks. Both women were admitted to the Department of Maternal and Fetal Medicine at the Kyiv and Kharkiv municipal perinatal clinics. Patients were observed using standard fetal monitoring methods as well as the non-invasive fetal electrocardiogram. The non-invasive fetal electrocardiographic recordings were analyzed retrospectively, where it is possible to identify the presence of the atrioventricular block. This study demonstrates, for the first time, the feasibility of the non-invasive fetal electrocardiogram as a supplementary method to diagnose of the fetal atrioventricular block. Combined with current fetal monitoring techniques, non-invasive fetal electrocardiography could support clinical decisions.

  2. Two innovative solutions based on fibre concrete blocks designed for building substructure

    NASA Astrophysics Data System (ADS)

    Pazderka, J.; Hájek, P.

    2017-09-01

    Using of fibers in a high-strength concrete allows reduction of the dimensions of small precast concrete elements, which opens up new ways of solution for traditional construction details in buildings. The paper presents two innovative technical solutions for building substructure: The special shaped plinth block from fibre concrete and the fibre concrete elements for new technical solution of ventilated floor. The main advantages of plinth block from fibre concrete blocks (compared with standard plinth solutions) is: easier and faster assembly, higher durability and thanks to the air cavity between the vertical part of the block, the building substructure reduced moisture level of structures under the waterproofing layer and a comprehensive solution to the final surface of building plinth as well as the surface of adjacent terrain. The ventilated floor based on fibre concrete precast blocks is an attractive structural alternative for tackling the problem of increased moisture in masonry in older buildings, lacking a functional waterproof layer in the substructure.

  3. EMG and mechanical changes during sprint starts at different front block obliquities.

    PubMed

    Guissard, N; Duchateau, J; Hainaut, K

    1992-11-01

    The effect of decreased front block obliquity on start velocity was studied during sprint starts. The electromyographic (EMG) activity of the medial gastrocnemius (MG), the soleus (Sol), and the vastus medialis (VM) was recorded and analyzed at a 70 degrees, a 50 degrees, and a 30 degrees angle between the foot plate surface and the horizontal. Integrated EMGs (IEMG) were compared with muscle length changes in the MG and Sol in relation to foot and knee movements. The results indicate that decreasing front block obliquity significantly (P < 0.05) increases the start velocity without any change to the total duration of the pushing phase and the overall EMG activity. This improvement in sprint start performance is associated with the enhanced contribution of the MG during eccentric and concentric phases of calf muscles contraction. In the "set position" the initial length of MG and Sol is increased at 50 degrees and 30 degrees as compared with 70 degrees. The subsequent stretch-shortening cycle is improved and contributes more effectively to the speed of the muscle shortening. Moreover, lengthening these muscles during the eccentric phase stretches the muscle spindles, and the reflex activities that contribute to the observed increase in the MG IEMG, are present when the slope of the block is reduced. The results indicate that decreasing front block obliquity induces neural and mechanical modifications that contribute to increasing the sprint start velocity without any increase in the duration of the pushing phase.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. One-dimensional poly(L-lysine)-block-poly(L-threonine) assemblies exhibit potent anticancer activity by enhancing membranolysis.

    PubMed

    Chen, Yu-Fon; Shiau, Ai-Li; Chang, Sue-Joan; Fan, Nai-Shin; Wang, Chung-Teng; Wu, Chao-Liang; Jan, Jeng-Shiung

    2017-06-01

    Herein, we report the oncolytic activity of cationic, one-dimensional (1D) fibril assemblies formed from coil-sheet poly(L-lysine)-block-poly(L-threonine) (PLL-b-PLT) block copolypeptides for cancer therapy. The 1D fibril assemblies can efficiently interact with negatively charged cellular and mitochondrial membranes via electrostatic interactions, leading to necrosis via membrane lysis and apoptosis via the mitochondria-lytic effect. The concept is analogous to that of 1D drug carriers that exhibit enhanced cell penetration. In comparison to free PLL chains, PLL-b-PLT fibril assemblies exhibit selective cytotoxicity toward cancer cells, low hemolysis activity, enhanced membranolytic activity, and a different apoptosis pathway, which may be due to differences in the peptide-membrane interactions. Antitumor studies using a metastatic LL2 lung carcinoma model indicate that the fibril assemblies significantly inhibited tumor growth, improved survival in tumor-bearing mice and suppressed lung metastasis without obvious body weight loss. An additive efficacy was also observed for treatment with both PLL-b-PLT and cisplatin. These results support the feasibility of using 1D fibril assemblies as potential apoptotic anticancer therapeutics. We report that cationic, one-dimensional (1D) fibril assemblies formed by coil-sheet poly(L-lysine)-block-poly(L-threonine) (PLL-b-PLT) block copolypeptides exhibited potent anticancer activity by enhancing membranolysis. The 1D fibril assemblies can efficiently interact with negatively charged cellular and mitochondrial membranes via electrostatic interactions, leading to necrosis via membrane lysis and apoptosis via mitochondria-lytic effect. Moreover, the fibril assemblies exhibited low hemolytic activity and selective cytotoxicity toward cancer cell, which is advantageous as compared to PLL and most antimicrobial/anticancerous peptides. This study provides a new concept of using cationic, 1D fibril assemblies for cancer therapy

  5. Paleomagnetic evidence that the central block of Salinia (California) is not a far-traveled terrane

    USGS Publications Warehouse

    Whidden, K.J.; Lund, S.P.; Bottjer, D.J.; Champion, D.; Howell, D.G.

    1998-01-01

    New paleomagnetic results from Late Cretaceous (75-85 m.y.) red beds on the central block of Salinia indicate that Salinia was located within 6?? (in latitude) of its current cratonal North American position during the Late Cretaceous (after correction for Neogene San Andreas Fault transport). The red beds formed as alluvial-fan overbank deposits with hematite cement deposited directly on Salinian granites in the La Panza Range. Paleomagnetic analysis shows two components of magnetization in the red beds, a low-blocking-temperature present-day overprint residing in goethite and a high-blocking-temperature (>600??) component residing in hematite. The hematite magnetization is a chemical remanent magnetization which formed soon after deposition during pedogenesis. The bedding-corrected hematite remanence contains a magnetic polarity stratigraphy with antipodal normal and reversed directions. Twenty-three Class I sites (??95 < 20??) have an average hematite direction with inclination = 54.4?? and declination = 18.2?? (??95 = 6.1??) after structural correction. These paleomagnetic data suggest that Salinia resided at about 35??N latitude during the Late Cretaceous, within 6?? of its current location adjacent to cratonal North America. By contrast, a summary of paleomagnetic data from the Peninsular Ranges terrane and the Sur-Obispo terrane, which are currently outboard of Salinia, shows northward transport of these terranes of 12,.o\\ to 22?? relative to their current locations in North America since the Cretaceous. The offsets increase systematically away from the craton with the most outboard Sur-Obispo terrane (which is composed of accretionary prism and distal forearc material) showing the largest degree of northward translation.

  6. An anatomical study of the transversus abdominis plane block: location of the lumbar triangle of Petit and adjacent nerves.

    PubMed

    Jankovic, Zorica B; du Feu, Frances M; McConnell, Patricia

    2009-09-01

    The transversus abdominis plane (TAP) block is a new technique for providing analgesia to the anterior abdominal wall. Most previous studies have used the lumbar triangle of Petit as a landmark for the block. In this cadaveric study, we determined the exact position and size of the lumbar triangle of Petit and identified the nerves affected by the TAP block. The position of the lumbar triangle of Petit was assessed unilaterally in 26 cadaveric specimens relative to reliably palpable surface landmarks. In addition, a series of dissections were performed to explore the course of the nerves blocked by the TAP. The mean distance from the midaxillary line along the iliac crest to the center of the base of the lumbar triangle of Petit at the level of the subcutaneous tissue and over the skin surface was 6.9 cm (range, 4.5-9.2 cm) and 9.3 cm (range, 4-15.1 cm), respectively. The center of the lumbar triangle of Petit was 1.4 cm above the iliac crest. The depth of the TAP at the lumbar triangle of Petit position was 0.5-4 cm and at the midaxillary line it was 0.5-2 cm. The average size of the lumbar triangle of Petit was 2.3 cm x 3.3 cm x 2.2 cm, with an average area of 3.63 +/- 1.93 cm2. The three cadaveric specimens we explored showed the nerves blocked by TAP passed lateral to the triangle. An incidental finding was that in 66% of specimens the lumbar triangle of Petit contained small branches of the subcostal artery. The lumbar triangles of Petit found in the specimens in this study were more posterior than the literature suggests. The position of the lumbar triangle of Petit varies largely and the size is relatively small. The relevant nerves to be blocked had not entered the TAP in the specimens in this study at the point of the lumbar triangle of Petit. At the midaxillary line, however, all the nerves were in the TAP.

  7. An Initial Look at Adjacent Band Interference Between Aeronautical Mobile Telemetry and Long-Term Evolution Wireless Service

    DTIC Science & Technology

    2016-07-04

    required analysis, and further testing. 15. SUBJECT TERMS Adjacent Channel Interference, ACI, LTE -A, LTE , PCM/FM, SOQPSK-TG, ARTM CPM, AWS-3, User...Interference, ACI, LTE -A, LTE , PCM/FM, SOQPSK-TG, ARTM CPM, AWS-3, User Equipment, UE, Evolved Node B, eNodeB, Resource Blocks INTRODUCTION “On...these questions make necessary an improved understanding of the interferers that can be obtained only by hands-on measurements . This work will

  8. Practical quantum private query of blocks based on unbalanced-state Bennett-Brassard-1984 quantum-key-distribution protocol

    NASA Astrophysics Data System (ADS)

    Wei, Chun-Yan; Gao, Fei; Wen, Qiao-Yan; Wang, Tian-Yin

    2014-12-01

    Until now, the only kind of practical quantum private query (QPQ), quantum-key-distribution (QKD)-based QPQ, focuses on the retrieval of a single bit. In fact, meaningful message is generally composed of multiple adjacent bits (i.e., a multi-bit block). To obtain a message from database, the user Alice has to query l times to get each ai. In this condition, the server Bob could gain Alice's privacy once he obtains the address she queried in any of the l queries, since each ai contributes to the message Alice retrieves. Apparently, the longer the retrieved message is, the worse the user privacy becomes. To solve this problem, via an unbalanced-state technique and based on a variant of multi-level BB84 protocol, we present a protocol for QPQ of blocks, which allows the user to retrieve a multi-bit block from database in one query. Our protocol is somewhat like the high-dimension version of the first QKD-based QPQ protocol proposed by Jacobi et al., but some nontrivial modifications are necessary.

  9. Practical quantum private query of blocks based on unbalanced-state Bennett-Brassard-1984 quantum-key-distribution protocol

    PubMed Central

    Wei, Chun-Yan; Gao, Fei; Wen, Qiao-Yan; Wang, Tian-Yin

    2014-01-01

    Until now, the only kind of practical quantum private query (QPQ), quantum-key-distribution (QKD)-based QPQ, focuses on the retrieval of a single bit. In fact, meaningful message is generally composed of multiple adjacent bits (i.e., a multi-bit block). To obtain a message from database, the user Alice has to query l times to get each ai. In this condition, the server Bob could gain Alice's privacy once he obtains the address she queried in any of the l queries, since each ai contributes to the message Alice retrieves. Apparently, the longer the retrieved message is, the worse the user privacy becomes. To solve this problem, via an unbalanced-state technique and based on a variant of multi-level BB84 protocol, we present a protocol for QPQ of blocks, which allows the user to retrieve a multi-bit block from database in one query. Our protocol is somewhat like the high-dimension version of the first QKD-based QPQ protocol proposed by Jacobi et al., but some nontrivial modifications are necessary. PMID:25518810

  10. An interprojection sensor fusion approach to estimate blocked projection signal in synchronized moving grid-based CBCT system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Hong; Kong, Vic; Ren, Lei

    2016-01-15

    Purpose: A preobject grid can reduce and correct scatter in cone beam computed tomography (CBCT). However, half of the signal in each projection is blocked by the grid. A synchronized moving grid (SMOG) has been proposed to acquire two complimentary projections at each gantry position and merge them into one complete projection. That approach, however, suffers from increased scanning time and the technical difficulty of accurately merging the two projections per gantry angle. Herein, the authors present a new SMOG approach which acquires a single projection per gantry angle, with complimentary grid patterns for any two adjacent projections, and usemore » an interprojection sensor fusion (IPSF) technique to estimate the blocked signal in each projection. The method may have the additional benefit of reduced imaging dose due to the grid blocking half of the incident radiation. Methods: The IPSF considers multiple paired observations from two adjacent gantry angles as approximations of the blocked signal and uses a weighted least square regression of these observations to finally determine the blocked signal. The method was first tested with a simulated SMOG on a head phantom. The signal to noise ratio (SNR), which represents the difference of the recovered CBCT image to the original image without the SMOG, was used to evaluate the ability of the IPSF in recovering the missing signal. The IPSF approach was then tested using a Catphan phantom on a prototype SMOG assembly installed in a bench top CBCT system. Results: In the simulated SMOG experiment, the SNRs were increased from 15.1 and 12.7 dB to 35.6 and 28.9 dB comparing with a conventional interpolation method (inpainting method) for a projection and the reconstructed 3D image, respectively, suggesting that IPSF successfully recovered most of blocked signal. In the prototype SMOG experiment, the authors have successfully reconstructed a CBCT image using the IPSF-SMOG approach. The detailed geometric features in

  11. An interprojection sensor fusion approach to estimate blocked projection signal in synchronized moving grid-based CBCT system.

    PubMed

    Zhang, Hong; Ren, Lei; Kong, Vic; Giles, William; Zhang, You; Jin, Jian-Yue

    2016-01-01

    A preobject grid can reduce and correct scatter in cone beam computed tomography (CBCT). However, half of the signal in each projection is blocked by the grid. A synchronized moving grid (SMOG) has been proposed to acquire two complimentary projections at each gantry position and merge them into one complete projection. That approach, however, suffers from increased scanning time and the technical difficulty of accurately merging the two projections per gantry angle. Herein, the authors present a new SMOG approach which acquires a single projection per gantry angle, with complimentary grid patterns for any two adjacent projections, and use an interprojection sensor fusion (IPSF) technique to estimate the blocked signal in each projection. The method may have the additional benefit of reduced imaging dose due to the grid blocking half of the incident radiation. The IPSF considers multiple paired observations from two adjacent gantry angles as approximations of the blocked signal and uses a weighted least square regression of these observations to finally determine the blocked signal. The method was first tested with a simulated SMOG on a head phantom. The signal to noise ratio (SNR), which represents the difference of the recovered CBCT image to the original image without the SMOG, was used to evaluate the ability of the IPSF in recovering the missing signal. The IPSF approach was then tested using a Catphan phantom on a prototype SMOG assembly installed in a bench top CBCT system. In the simulated SMOG experiment, the SNRs were increased from 15.1 and 12.7 dB to 35.6 and 28.9 dB comparing with a conventional interpolation method (inpainting method) for a projection and the reconstructed 3D image, respectively, suggesting that IPSF successfully recovered most of blocked signal. In the prototype SMOG experiment, the authors have successfully reconstructed a CBCT image using the IPSF-SMOG approach. The detailed geometric features in the Catphan phantom were mostly

  12. Block LU factorization

    NASA Technical Reports Server (NTRS)

    Demmel, James W.; Higham, Nicholas J.; Schreiber, Robert S.

    1992-01-01

    Many of the currently popular 'block algorithms' are scalar algorithms in which the operations have been grouped and reordered into matrix operations. One genuine block algorithm in practical use is block LU factorization, and this has recently been shown by Demmel and Higham to be unstable in general. It is shown here that block LU factorization is stable if A is block diagonally dominant by columns. Moreover, for a general matrix the level of instability in block LU factorization can be founded in terms of the condition number kappa(A) and the growth factor for Gaussian elimination without pivoting. A consequence is that block LU factorization is stable for a matrix A that is symmetric positive definite or point diagonally dominant by rows or columns as long as A is well-conditioned.

  13. Uplink scheduling and adjacent-channel coupling loss analysis for TD-LTE deployment.

    PubMed

    Yeo, Woon-Young; Moon, Sung Ho; Kim, Jae-Hoon

    2014-01-01

    TD-LTE, one of the two duplexing modes in LTE, operates in unpaired spectrum and has the advantages of TDD-based technologies. It is expected that TD-LTE will be more rapidly deployed in near future and most of WiMax operators will upgrade their networks to TD-LTE gradually. Before completely upgrading to TD-LTE, WiMax may coexist with TD-LTE in an adjacent frequency band. In addition, multiple TD-LTE operators may deploy their networks in adjacent bands. When more than one TDD network operates in adjacent frequency bands, severe interference may happen due to adjacent channel interference (ACI) and unsynchronized operations. In this paper, coexistence issues between TD-LTE and other systems are analyzed and coexistence requirements are provided. This paper has three research objectives. First, frame synchronization between TD-LTE and WiMax is discussed by investigating possible combinations of TD-LTE and WiMax configurations. Second, an uplink scheduling algorithm is proposed to utilize a leakage pattern of ACI in synchronized operations. Third, minimum requirements for coexistence in unsynchronized operations are analyzed by introducing a concept of adjacent-channel coupling loss. From the analysis and simulation results, we can see that coexistence of TD-LTE with other TDD systems is feasible if the two networks are synchronized. For the unsynchronized case, some special cell-site engineering techniques may be required to reduce the ACI.

  14. Signalment, clinical signs, and prognostic indicators associated with high-grade second- or third-degree atrioventricular block in dogs: 124 cases (January 1, 1997-December 31, 1997).

    PubMed

    Schrope, Donald P; Kelch, William J

    2006-06-01

    To evaluate signalment, clinical signs, and prognosis associated with high-grade second- or third-degree atrioventricular block (AVB) in dogs. Retrospective case series. 124 dogs. Data were gathered from ECGs, veterinarian questionnaires, echocardiograms, and radiographs submitted for review; compared with data from a large control group; and examined for association between variables and duration of survival. A new classification system for AVB was evaluated. Afghan, Catahoula Leopard Dog, Chow Chow, Cocker Spaniel, German Wirehaired Pointer, and Labrador Retriever breeds were predisposed to high-grade second- or third-degree AVB. Heavier, older, and sexually intact female dogs were overrepresented in the study group. Weakness, lethargy, exercise intolerance, and syncope were the most common clinical signs. The presence of clinical signs was not associated with duration of survival. Dogs with high-grade second-degree AVB had a duration of survival similar to that of dogs with third-degree AVB. Dogs with high-grade second- or third-degree AVB were at high risk for sudden death in the first 6 months after diagnosis. High ventricular escape rhythm rate and narrow escape-complex QRS width were negatively associated with duration of survival. Pacemaker implantation had a significant positive association with survival. Pacemaker implantation should be strongly considered in all dogs with high-grade second- or third-degree AVB regardless of whether clinical signs are evident. If medical treatment is warranted, vagolytic medications may be the best choice. A new classification system for AVB may merit further investigation.

  15. The formation and analysis of a 5 deg equal area block terrestrial gravity field

    NASA Technical Reports Server (NTRS)

    Rapp, R. H.

    1972-01-01

    A set of 23,355 1 degree x 1 degree mean free air anomalies were used to predict a set of 5 degree equal area anomalies and their standard errors. Using the 1 degree data incorporating geophysically predicted values of ACIC, 1283 5 degree blocks were computed. Excluding the geophysically predicted anomalies 1249 blocks were computed. The 1 degree data were also used to compute covariance functions and the equatorial gravity and flattening implied by this data. The predicted anomalies were supplemented by model anomalies to form a complete 1654 global anomaly field. These data were used in a weighted least squares to determine potential coefficients to degree 15, and in a summation type formulation to determine potential coefficients to degree 25. These potential coefficients sets are compared to recent satellite determinations.

  16. One-degree-of-freedom spherical model for the passive motion of the human ankle joint.

    PubMed

    Sancisi, Nicola; Baldisserri, Benedetta; Parenti-Castelli, Vincenzo; Belvedere, Claudio; Leardini, Alberto

    2014-04-01

    Mathematical modelling of mobility at the human ankle joint is essential for prosthetics and orthotic design. The scope of this study is to show that the ankle joint passive motion can be represented by a one-degree-of-freedom spherical motion. Moreover, this motion is modelled by a one-degree-of-freedom spherical parallel mechanism model, and the optimal pivot-point position is determined. Passive motion and anatomical data were taken from in vitro experiments in nine lower limb specimens. For each of these, a spherical mechanism, including the tibiofibular and talocalcaneal segments connected by a spherical pair and by the calcaneofibular and tibiocalcaneal ligament links, was defined from the corresponding experimental kinematics and geometry. An iterative procedure was used to optimize the geometry of the model, able to predict original experimental motion. The results of the simulations showed a good replication of the original natural motion, despite the numerous model assumptions and simplifications, with mean differences between experiments and predictions smaller than 1.3 mm (average 0.33 mm) for the three joint position components and smaller than 0.7° (average 0.32°) for the two out-of-sagittal plane rotations, once plotted versus the full flexion arc. The relevant pivot-point position after model optimization was found within the tibial mortise, but not exactly in a central location. The present combined experimental and modelling analysis of passive motion at the human ankle joint shows that a one degree-of-freedom spherical mechanism predicts well what is observed in real joints, although its computational complexity is comparable to the standard hinge joint model.

  17. Thermokarst in pingos and adjacent collapse scar bogs in interior Alaska

    NASA Astrophysics Data System (ADS)

    Douglas, T. A.; Turetsky, M. R.

    2017-12-01

    A region of discontinuous permafrost 50 kilometers southeast of Fairbanks, Alaska exhibits rapid thermokarst and landscape change. The area contains a dozen pingos (hydrolaccoliths), mounds of ice covered by earth material typically 100 meters across and 20 meters above the surrounding ground surface. The pingos have sunken craters in their centers formed through melting and collapse of an inner ice lens core. Adjacent to the pingos are collapse scar bogs in various states of formation and ice wedge terrain undergoing thaw subsidence to polygons and thermokarst mounds (baydzherakhs). With a mean annual temperature of -1 degree C the area contains warm ecosystem-protected permafrost vulnerable to thaw. We analyzed historical imagery to the 1970s to track water features in a subset of pingos. The craters have expanded over the past few decades suggesting melting and collapse of the ice cored center and potential permafrost degradation along pingo margins. Collapse scar bogs in adjacent low-elevation terrain are roughly the same size as the pingos but have little vertical elevation gradient compared to the surrounding terrain. Electrical resistivity tomography (ERT) measurements, high resolution GPS surveys, SIPRE coring, and thaw depth probing were focused along nine 400 meter transects across three of the pingos to identify relationships between geophysical properties, permafrost composition, seasonal thaw, and ecological state. A large ( 40 meters across and 20 meters thick) lens shaped region of thawed permafrost is evident in the ERT results about 10 meters below the ground surface in the center of one pingo we surveyed in detail. This is believed to be the original ice cored region of the pingo that has melted. A thin (1-5 meters thick) layer of permafrost is present above this thawed region while the rampart margins surrounding the pingo are underlain by thick (10-30 m) permafrost. The pingo and thermokarst features reside in a location where rapid permafrost

  18. Coherent manipulation of an NV center and one carbon nuclear spin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scharfenberger, Burkhard; Nemoto, Kae; Munro, William J.

    2014-12-04

    We study a three-qubit system formed by the NV center’s electronic and nuclear spin plus an adjacent spin 1/2 carbon {sup 13}C. Specifically, we propose a manipulation scheme utilizing the hyperfine coupling of the effective S=1 degree of freedom of the vacancy electrons to the two adjacent nuclear spins to achieve accurate coherent control of all three qubits.

  19. Agricultural Intensification Exacerbates Spillover Effects on Soil Biogeochemistry in Adjacent Forest Remnants

    PubMed Central

    Didham, Raphael K.; Barker, Gary M.; Bartlam, Scott; Deakin, Elizabeth L.; Denmead, Lisa H.; Fisk, Louise M.; Peters, Jennifer M. R.; Tylianakis, Jason M.; Wright, Hannah R.; Schipper, Louis A.

    2015-01-01

    Land-use intensification is a central element in proposed strategies to address global food security. One rationale for accepting the negative consequences of land-use intensification for farmland biodiversity is that it could ‘spare’ further expansion of agriculture into remaining natural habitats. However, in many regions of the world the only natural habitats that can be spared are fragments within landscapes dominated by agriculture. Therefore, land-sparing arguments hinge on land-use intensification having low spillover effects into adjacent protected areas, otherwise net conservation gains will diminish with increasing intensification. We test, for the first time, whether the degree of spillover from farmland into adjacent natural habitats scales in magnitude with increasing land-use intensity. We identified a continuous land-use intensity gradient across pastoral farming systems in New Zealand (based on 13 components of farmer input and soil biogeochemistry variables), and measured cumulative off-site spillover effects of fertilisers and livestock on soil biogeochemistry in 21 adjacent forest remnants. Ten of 11 measured soil properties differed significantly between remnants and intact-forest reference sites, for both fenced and unfenced remnants, at both edge and interior. For seven variables, the magnitude of effects scaled significantly with magnitude of surrounding land-use intensity, through complex interactions with fencing and edge effects. In particular, total C, total N, δ15N, total P and heavy-metal contaminants of phosphate fertilizers (Cd and U) increased significantly within remnants in response to increasing land-use intensity, and these effects were exacerbated in unfenced relative to fenced remnants. This suggests movement of livestock into surrounding natural habitats is a significant component of agricultural spillover, but pervasive changes in soil biogeochemistry still occur through nutrient spillover channels alone, even in fenced

  20. Enzymatic preparation of novel thermoplastic di-block copolyesters containing poly[(R)-3-hydroxybutyrate] and poly(epsilon-caprolactone) blocks via ring-opening polymerization.

    PubMed

    Dai, Shiyao; Li, Zhi

    2008-07-01

    Enzymatic modification of a microbial polyester was achieved by the ring-opening polymerization of epsilon-caprolactone (CL) with low-molecular weight telechelic hydroxylated poly[( R)-3-hydroxybutyrate] (PHB-diol) as initiator and Novozym 435 (immobilized Candida antarctica Lipase B) as catalyst in anhydrous 1,4-dioxane or toluene. The ring-opening polymerization was investigated at different conditions with two different types of PHB-diols: PHB-diol(P), containing a primary OH and a secondary OH end groups, and PHB-diol(M), consisting of 91% PHB-diol(P) and 9% PHB-diol containing two secondary OH end groups. The reactions were followed by GPC analyses of the resulting polymers at different time points, and the optimal conditions were established to be 70 degrees C at a weight ratio of CL/enzyme/solvent of 8:1:24. The ring-opening polymerization of CL with PHB-diol(M) (Mn of 2380, NMR) at the molar ratio of 50:1 under the optimal conditions in 1,4-dioxane gave the corresponding poly[HB(56 wt %)-co-CL(44 wt %)] with Mn (NMR) of 3900 in 66% yield. Polymerization of CL and PHB-diol(P) ( Mn of 2010, NMR) at the same condition in toluene gave the corresponding poly[HB(28 wt %)-co-CL(72 wt %)] with Mn (NMR) of 7100 in 86% yield. Both polymers were characterized by (1)H and (13)C NMR and IR analyses as di-block copolyesters containing a PHB block with a secondary OH end group and a poly(epsilon-caprolactone) (PCL) block with a primary OH end group. NMR analyses and control experiments suggested no formation of random copolymers and no change of the PHB block during the reaction. The enzymatic ring-opening polymerization was selectively initiated by the primary OH group of PHB-diol, whereas the secondary OH group remained as an end group in the final polymers. The thermal properties of the di-block poly(HB-co-CL)s were analyzed by DSC, with excellent T g values for the elastomer domain: poly[HB(56 wt %)- co-CL(44 wt %)] with M n (NMR) of 3900 demonstrated a T g of -57

  1. Uplink Scheduling and Adjacent-Channel Coupling Loss Analysis for TD-LTE Deployment

    PubMed Central

    Yeo, Woon-Young; Moon, Sung Ho

    2014-01-01

    TD-LTE, one of the two duplexing modes in LTE, operates in unpaired spectrum and has the advantages of TDD-based technologies. It is expected that TD-LTE will be more rapidly deployed in near future and most of WiMax operators will upgrade their networks to TD-LTE gradually. Before completely upgrading to TD-LTE, WiMax may coexist with TD-LTE in an adjacent frequency band. In addition, multiple TD-LTE operators may deploy their networks in adjacent bands. When more than one TDD network operates in adjacent frequency bands, severe interference may happen due to adjacent channel interference (ACI) and unsynchronized operations. In this paper, coexistence issues between TD-LTE and other systems are analyzed and coexistence requirements are provided. This paper has three research objectives. First, frame synchronization between TD-LTE and WiMax is discussed by investigating possible combinations of TD-LTE and WiMax configurations. Second, an uplink scheduling algorithm is proposed to utilize a leakage pattern of ACI in synchronized operations. Third, minimum requirements for coexistence in unsynchronized operations are analyzed by introducing a concept of adjacent-channel coupling loss. From the analysis and simulation results, we can see that coexistence of TD-LTE with other TDD systems is feasible if the two networks are synchronized. For the unsynchronized case, some special cell-site engineering techniques may be required to reduce the ACI. PMID:24707214

  2. Binding Blocks: Building the Universe One Nucleus at a Time

    ERIC Educational Resources Information Center

    Diget, C. Aa.; Pastore, A.; Leech, K.; Haylett, T.; Lock, S.; Sanders, T.; Shelley, M.; Willett, H. V.; Keegans, J.; Sinclair, L.; Simpson, E. C.

    2017-01-01

    We present a new teaching and outreach activity based around the construction of a three-dimensional chart of isotopes using LEGO® bricks. The activity, "binding blocks", demonstrates nuclear and astrophysical processes through a seven-meter chart of all nuclear isotopes, built from over 26000 LEGO® bricks. It integrates A-Level and GCSE…

  3. Energy resolution in semiconductor gamma radiation detectors using heterojunctions and methods of use and preparation thereof

    DOEpatents

    Nikolic, Rebecca J.; Conway, Adam M.; Nelson, Art J.; Payne, Stephen A.

    2012-09-04

    In one embodiment, a system comprises a semiconductor gamma detector material and a hole blocking layer adjacent the gamma detector material, the hole blocking layer resisting passage of holes therethrough. In another embodiment, a system comprises a semiconductor gamma detector material, and an electron blocking layer adjacent the gamma detector material, the electron blocking layer resisting passage of electrons therethrough, wherein the electron blocking layer comprises undoped HgCdTe. In another embodiment, a method comprises forming a hole blocking layer adjacent a semiconductor gamma detector material, the hole blocking layer resisting passage of holes therethrough. Additional systems and methods are also presented.

  4. Ballistic Blocks Surrounding Kilauea's Caldera

    NASA Astrophysics Data System (ADS)

    Swanson, D.; Zolkos, S.; Haravitch, B.

    2010-12-01

    Thousands of lithic blocks dot the surface around Kilauea’s caldera, erupted ballistically at the end of the 1790 eruption or soon thereafter. Most of the blocks occur in the western and southern sectors, probably reflecting the proximity of vents on the caldera floor. We mapped the ejecta field, measuring most of the blocks with nominal diameters ((a+b+c)/3) more than 75 cm and many of the smaller ones, noting distinctive lithologies. The distributions, sizes, and lithologies suggest 7-8 different ballistic bursts from 3-4 generalized vent areas. We measured 15 blocks with nominal diameters (ND) of 150-201 cm, 169 blocks with ND 100-149 cm, 308 blocks with ND 75-99 cm, 684 blocks with ND 50-74 cm, and 545 blocks with ND 25-49 cm. The smaller blocks were measured only in outlying areas, where they were the largest in the neighborhood, but they occur throughout the field. Twelve blocks with ND >150 cm lie within 1.7 km west and south of the center of Halema`uma`u; a vent near this location likely erupted the blocks. Three of the largest blocks, however, are 2.2-2.7 km north of Halema`uma`u and probably came from a more northerly vent. This interpretation is supported by the distributions of all blocks with ND >100 cm, which define at least 4, and possibly 5, different dispersal lobes; three cluster near Halema`uma`u, one is slightly north, and the one with the three large blocks is still farther north. The blocks have typical lithologies for Kilauea’s summit, including coarse basalt or fine gabbro derived from the centers of thick flows, solidified lakes, or small intrusions. Three lithologies are distinctive and help define 3, possibly 4, discrete bursts. Blocks of fine-grained basalt riddled with segregation veins occur only in a lobe 1.3 km wide reaching as far as 1.8 km southwest of Halema`uma`u; this lobe overlaps slightly with one defined by block size but is mostly distinct and probably indicates a separate burst. A cluster of blocks with puffy, somewhat

  5. A novel revision to the classical transnasal topical sphenopalatine ganglion block for the treatment of headache and facial pain.

    PubMed

    Candido, Kenneth D; Massey, Scott T; Sauer, Ruben; Darabad, Raheleh Rahimi; Knezevic, Nebojsa Nick

    2013-01-01

    The sphenopalatine ganglion (SPG) is located with some degree of variability near the tail or posterior aspect of the middle nasal turbinate. The SPG has been implicated as a strategic target in the treatment of various headache and facial pain conditions, some of which are featured in this manuscript. Interventions for blocking the SPG range from minimally to highly invasive procedures often associated with great cost and unfavorable risk profiles. The purpose of this pilot study was to present a novel, FDA-cleared medication delivery device, the Tx360® nasal applicator, incorporating a transnasal needleless topical approach for SPG blocks. This study features the technical aspects of this new device and presents some limited clinical experience observed in a small series of head and face pain cases. Case series. Pain management center, part of teaching-community hospital, major metropolitan city, United States. After Institutional Review Board (IRB) approval, the technical aspects of this technique were examined on 3 patients presenting with various head and face pain conditions including trigeminal neuralgia (TN), chronic migraine headache (CM), and post-herpetic neuralgia (PHN). The subsequent response to treatment and quality of life was quantified using the following tools: the 11-point Numeric Rating Scale (NRS), Modified Brief Pain Inventory - short form (MBPI-sf), Patient Global Impression of Change (PGIC), and patient satisfaction surveys. The Tx360® nasal applicator was used to deliver 0.5 mL of ropivacaine 0.5% and 2 mg of dexamethasone for SPG block. Post-procedural assessments were repeated at 15 and 30 minutes, and on days one, 7, 14, and 21 with a final assessment at 28 days post-treatment. All patients were followed for one year. Individual patients received up to 10 SPG blocks, as clinically indicated, after the initial 28 days. Three women, ages 43, 18, and 15, presented with a variety of headache and face pain disorders including TN, CM, and

  6. Addition of dexmedetomidine to bupivacaine in supraclavicular brachial plexus block.

    PubMed

    Aksu, Recep; Bicer, Cihangir

    2017-06-26

    Research is ongoing to determine the lowest dose of local anesthetics in brachial plexus block that provides adequate anesthesia and postoperative analgesia and reduces complications related to local anesthetics. Patients 18-65 years of age who underwent upper limb surgery and who received ultrasound-guided supraclavicular brachial plexus block at the Erciyes University Faculty of Medicine Hospital between February 2014 and January 2015 were included in the study (n=50). Supraclavicular brachial plexus blocks were performed on Group B cases by adding 30 ml 0.33% bupivacaine and on Group BD cases by adding 15 ml 0.33% bupivacaine and 1 µg / kg dexmedetomidine. Block success was evaluated by the onset and block duration of motor and sensory block and the duration of analgesia. The block success of Group B and Group BD was 92.6% and 89.3%, respectively (P = 1.000). Onset time of sensory block, degree of sensory block, duration of sensory block, onset time of motor block, degree of motor block and duration of motor block were similar in both groups in the intergroup comparison (P > 0.05). Duration of analgesia and the operative conditions of groups were similar (P > 0.05). In the implementation of ultrasound-guided supraclavicular brachial plexus block, block success, sensory and motor block and analgesia duration were similar for patients anaesthetized with 30 ml of bupivacaine in comparison with dexmedetomidine+bupivacaine (when the bupivacaine dose was reduced by 50% by the addition of the adjuvant).

  7. Self-doped microphase separated block copolymer electrolyte

    DOEpatents

    Mayes, Anne M.; Sadoway, Donald R.; Banerjee, Pallab; Soo, Philip; Huang, Biying

    2002-01-01

    A polymer electrolyte includes a self-doped microphase separated block copolymer including at least one ionically conductive block and at least one second block that is immiscible in the ionically conductive block, an anion immobilized on the polymer electrolyte and a cationic species. The ionically conductive block provides a continuous ionically conductive pathway through the electrolyte. The electrolyte may be used as an electrolyte in an electrochemical cell.

  8. Inexpensive position sensitive detector block for dedicated PET cameras using 40-mm diameter PMT in quadrant sharing configuration

    NASA Astrophysics Data System (ADS)

    Uribe, J.; Aykac, M.; Baghaei, H.; Li, Hongdi; Wang, Yu; Liu, Yaqiang; Wong, V.; Xing, Tao; Ramirez, R.; Wong, Wai-Hoi

    2003-06-01

    Recent approvals by CMS (HCFA) for reimbursement of positron emission tomography (PET) scans fuels the rapid grow of the PET market, thus creating the need for more affordable dedicated PET scanners. The objective of the work presented here was the development of a BGO position-sensitive block with similar detector area (40 mm /spl times/ 40 mm) and same number of crystals (8 /spl times/ 8) as the block of a commercial BGO PET, using the less expensive photomultiplier quadrant sharing (PQS) technique. This block is coupled to four single-anode 40-mm diameter photomultipliers (PMT) instead of the 19-mm PMT used in a popular commercial BGO PET, and each PMT is shared by four adjacent detector blocks. Potentially, this design needs only 25% of the number of PMT used in the commercial BGO PET. In order not to waste the unused half-row of PMT at the edges of a detector panel/module when the module is made up solely of square blocks, an extended rectangular block has to be developed for the edge-blocks in the module, which maximized the use of the PMT and minimized the gap between modules. Only the extended block needs to be developed to derive the design for all the blocks in the module because the symmetric square block uses the same light-distributing partitions as those along the short side of the extended rectangular block. White-paint masks applied with accurate templates and airbrush were fine-tuned for every pair of adjacent crystals. The experimental block developed in this study provided good crystal-decoding. The composite energy spectrum of all 64 crystals showed a prominent photopeak. The worst crystal sitting in the air space between 4 round PMTs still has 60% of the signal pulse height as the best crystal. The average energy resolution was 21.8% for 511 keV gamma (range 17% - 28.7%) that compared well with the 22% - 44% measured with GE and CTI blocks. The image resolution provided by the PQS blocks is expected to be comparable to that of commercial BGO

  9. Skin aging parameters: A window to heart block.

    PubMed

    Roshdy, Hisham Samir; Soliman, Mohammad Hassan; El-Dosouky, Ibtesam Ibrahim; Ghonemy, Soheir

    2018-01-01

    Skin acts as a mirror to the internal state of the body. We tried to find the relation between skin aging parameters and the incidence of degenerative AV block. This study included 97 patients divided into 2 groups; group D comprised 49 patients with advanced-degree AV block, and group C comprised the 48 matched control group. All were subjected to full history taking, thorough clinical examination, calculation of intrinsic skin aging score, and resting 12-lead surface electrocardiography (ECG). ECG for all patients assessed left ventricular end-systolic diameter, left ventricular end-diastolic diameter, ejection fraction, left atrium (LA) diameter, aortic root diameter, mitral annular calcification, aortic sclerosis. Coronary angiography was also performed when indicated for patients in group D. Patients in group D had a higher percentages of uneven pigmentation, fine skin wrinkles, lax appearance, seborrheic keratosis, total score > 7 (38 [77.55%] vs 10 [20.83%]), mitral annular calcification score of 33 (67.34%) vs 5 (10.41%), aortic sclerosis score of 21 (42.85%) vs 4 (8.33%), and mean LA diameter of 39.98 ± 5.52 vs 36.21 ± 3 mm (P < 0.001). Total score > 6 is the best cutoff value to predict advanced-degree heart block with 89.79% sensitivity and 64.58% specificity. Seborrheic keratosis was the strongest independent predictor. Any population with a total intrinsic skin aging score of >6 is at high risk for developing advanced-degree AV block and should undergo periodic ECG follow-up for early detection of any conduction disturbance in the early asymptomatic stages to minimize sudden cardiac death. © 2017 Wiley Periodicals, Inc.

  10. Structure of clusters and building blocks in amylopectin from African rice accessions.

    PubMed

    Gayin, Joseph; Abdel-Aal, El-Sayed M; Marcone, Massimo; Manful, John; Bertoft, Eric

    2016-09-05

    Enzymatic hydrolysis in combination with gel-permeation and anion-exchange chromatography techniques were employed to characterise the composition of clusters and building blocks of amylopectin from two African rice (Oryza glaberrima) accessions-IRGC 103759 and TOG 12440. The samples were compared with one Asian rice (Oryza sativa) sample (cv WITA 4) and one O. sativa×O. glaberrima cross (NERICA 4). The average DP of clusters from the African rice accessions (ARAs) was marginally larger (DP=83) than in WITA 4 (DP=81). However, regarding average number of chains, clusters from the ARAs represented both the smallest and largest clusters. Overall, the result suggested that the structure of clusters in TOG 12440 was dense with short chains and high degree of branching, whereas the situation was the opposite in NERICA 4. IRGC 103759 and WITA 4 possessed clusters with intermediate characteristics. The commonest type of building blocks in all samples was group 2 (single branched dextrins) representing 40.3-49.4% of the blocks, while groups 3-6 were found in successively lower numbers. The average number of building blocks in the clusters was significantly larger in NERICA 4 (5.8) and WITA 4 (5.7) than in IRGC 103759 and TOG 12440 (5.1 and 5.3, respectively). Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Diffusion-Weighted MRI Assessment of Adjacent Disc Degeneration After Thoracolumbar Vertebral Fractures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Noriega, David C., E-mail: dcnoriega1970@gmail.com; Marcia, Stefano, E-mail: stemarcia@gmail.com; Ardura, Francisco, E-mail: fardura@ono.com

    ObjectiveThe purpose of this study was to assess, by the mean apparent diffusion coefficient (ADC), if a relationship exists between disc ADC and MR findings of adjacent disc degeneration after thoracolumbar fractures treated by anatomic reduction using vertebral augmentation (VAP).Materials and MethodsTwenty non-consecutive patients (mean age 50.7 years; range 45–56) treated because of vertebral fractures, were included in this study. There were 10 A3.1 and 10 A1.2 fractures (AO classification). Surgical treatment using VAP was applied in 14 cases, and conservative in 6 patients. MRI T2-weighted images and mapping of apparent diffusion coefficient (ADC) of the intervertebral disc adjacent to themore » fractured segment were performed after a mean follow-up of 32 months. A total of 60 discs, 3 per patient, were analysed: infra-adjacent, supra-adjacent and a control disc one level above the supra-adjacent.ResultsNo differences between patients surgically treated and those following a conservative protocol regarding the average ADC values obtained in the 20 control discs analysed were found. Considering all discs, average ADC in the supra-adjacent level was lower than in the infra-adjacent (1.35 ± 0.12 vs. 1.53 ± 0.06; p < 0.001). Average ADC values of the discs used as a control were similar to those of the infra-adjacent level (1.54 ± 0.06). Compared to surgically treated patients, discs at the supra-adjacent fracture level showed statistically significant lower values in cases treated conservatively (p < 0.001). The variation in the delay of surgery had no influence on the average values of ADC at any of the measured levels.ConclusionsADC measurements of the supra-adjacent discs after a mean follow-up of 32 months following thoracolumbar fractures, showed that restoration of the vertebral collapse by minimally invasive VAP prevents posttraumatic disc degeneration.« less

  12. Improving the Curie depth estimation through optimizing the spectral block dimensions of the aeromagnetic data in the Sabalan geothermal field

    NASA Astrophysics Data System (ADS)

    Akbar, Somaieh; Fathianpour, Nader

    2016-12-01

    The Curie point depth is of great importance in characterizing geothermal resources. In this study, the Curie iso-depth map was provided using the well-known method of dividing the aeromagnetic dataset into overlapping blocks and analyzing the power spectral density of each block separately. Determining the optimum block dimension is vital in improving the resolution and accuracy of estimating Curie point depth. To investigate the relation between the optimal block size and power spectral density, a forward magnetic modeling was implemented on an artificial prismatic body with specified characteristics. The top, centroid, and bottom depths of the body were estimated by the spectral analysis method for different block dimensions. The result showed that the optimal block size could be considered as the smallest possible block size whose corresponding power spectrum represents an absolute maximum in small wavenumbers. The Curie depth map of the Sabalan geothermal field and its surrounding areas, in the northwestern Iran, was produced using a grid of 37 blocks with different dimensions from 10 × 10 to 50 × 50 km2, which showed at least 50% overlapping with adjacent blocks. The Curie point depth was estimated in the range of 5 to 21 km. The promising areas with the Curie point depths less than 8.5 km are located around Mountain Sabalan encompassing more than 90% of known geothermal resources in the study area. Moreover, the Curie point depth estimated by the improved spectral analysis is in good agreement with the depth calculated from the thermal gradient data measured in one of the exploratory wells in the region.

  13. Lyme carditis with isolated left bundle branch block and myocarditis successfully treated with oral doxycycline.

    PubMed

    Cunha, Burke A; Elyasi, Maekal; Singh, Prince; Jimada, Ismail

    2018-01-01

    Lyme disease may present with a variety of cardiac manifestations ranging from first degree to third degree heart block. Cardiac involvement with Lyme disease may be asymptomatic, or symptomatic. Atrioventrical conduction abnormalities are the most common manifestation of Lyme carditis. Less common, are alternating right bundle branch block (RBBB) and left bundle branch block (LBBB). We present an interesting case of a young male whose main manifestation of Lyme carditis was isolated LBBB. He also had mild Lyme myocarditis. The patient was successfully treated with oral doxycycline, and his isolated LBBB and myocarditis rapidly resolved.

  14. [Ultrasound-guided peripheral nerve block at wrist level for the treatment of idiopathic palmar hyperhidrosis with botulinum toxin].

    PubMed

    Olea, E; Fondarella, A; Sánchez, C; Iriarte, I; Almeida, M V; Martínez de Salinas, A

    2013-12-01

    Evaluation of pain and degree of satisfaction in patients undergoing ultrasound-assisted peripheral regional block for the treatment of idiopathic palmar hyperhidrosis with botulinum toxin. A descriptive, observational study of patients with palmar hyperhidrosis treated with botulinum toxin A, who underwent ultrasound-guided peripheral regional block of the median and ulnar nerves with 3 ml of mepivacaine 1% in each one. The radial nerve block was injected in the anatomical snuffbox. After establishing blocking, the dermatologist performed a mapping and injected around 100 IU of botulinum toxin across the whole palm. The pain experienced during the injection of botulinum toxin was evaluated by verbal numerical scale (from 0 to 10), along with the degree of satisfaction with the anesthetic technique, and the post-anesthetic complications. A total of 40 patients were enrolled in the study, 11 men and 29 women with no significant differences. The pain intensity assessed with verbal numerical scale was 1.03 (standard deviation of 1.37). No patients had a value greater than 5. The degree of patient satisfaction with the anesthetic technique was very good for 85% of the patients, and good for 7.5%. There were no complications related to type of anesthesia. The ultrasound-assisted peripheral regional block could be a simple, effective and safe technique for patients undergoing palmar injection of botulinum toxin. Pain intensity was very low, and it provided a very good level of satisfaction in most patients. Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

  15. Paleogeographic evolution of foldbelts adjacent to petroleum basins of Venezuela and Trinidad

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goodman, E.D.; Koch, P.S.; Summa, L.L.

    1996-08-01

    The foldbelts of Venezuela and Trinidad have shaped the history of adjacent sedimentary basins. A set of paleogeographic maps on reconstructed bases depict the role of foldbelts in the development of the sedimentary basins of Venezuela. Some of the foldbelts are inverted, pre-Tertiary graben/passive margin systems. Other foldbelts are allochthonous nappes or parautochthons that override the Mesozoic passive margin hinge without inversion. The emergence of these foldbelts changed the course of existing river systems and provided a new source for sediments and maturation in adjacent deeps. The Merida Andes area was remobilized beginning in the Early Miocene as a zonemore » of lateral shear, along which the Bonaire Block has moved over 200 km to the northeast, dismembering the Maracaibo and Barinas basins. Late Miocene to Recent transpression and fault reactivation have driven rapid Andean uplift with thrust-related subsidence and maturation (e.g., SE Maracaibo foredeep). To the east, uplift and erosion of the Serrania del Interior (1) curtailed mid-Tertiary fluvial systems flowing northward from the igneous and sedimentary rocks of the Guyana Shield, deflecting them eastward, and (2) removed the thick early Miocene foredeep fill into a younger foredeep. Thus, the fold-thrust belts and sedimentary basins in this region are linked in their evolutionary histories.« less

  16. Practical quantum private query of blocks based on unbalanced-state Bennett-Brassard-1984 quantum-key-distribution protocol.

    PubMed

    Wei, Chun-Yan; Gao, Fei; Wen, Qiao-Yan; Wang, Tian-Yin

    2014-12-18

    Until now, the only kind of practical quantum private query (QPQ), quantum-key-distribution (QKD)-based QPQ, focuses on the retrieval of a single bit. In fact, meaningful message is generally composed of multiple adjacent bits (i.e., a multi-bit block). To obtain a message a1a2···al from database, the user Alice has to query l times to get each ai. In this condition, the server Bob could gain Alice's privacy once he obtains the address she queried in any of the l queries, since each a(i) contributes to the message Alice retrieves. Apparently, the longer the retrieved message is, the worse the user privacy becomes. To solve this problem, via an unbalanced-state technique and based on a variant of multi-level BB84 protocol, we present a protocol for QPQ of blocks, which allows the user to retrieve a multi-bit block from database in one query. Our protocol is somewhat like the high-dimension version of the first QKD-based QPQ protocol proposed by Jacobi et al., but some nontrivial modifications are necessary.

  17. Management and outcome of topical beta-blockerinduced atrioventricular block

    PubMed Central

    Özcan, Kazım Serhan; Güngör, Barış; Tekkeşin, Ahmet İlker; Altay, Servet; Ekmekçi, Ahmet; Toprak, Ercan; Yıldırım, Ersin; Çalık, Nazmi; Alper, Ahmet Taha; Gürkan, Kadir; Erdinler, İzzet; Osmonov, Damirbek

    2015-01-01

    Summary Background Topical beta-blockers have a well-established role in the treatment of glaucoma. We aimed to investigate the outcome of patients who developed symptomatic atrioventricular (AV) block induced by topical beta-blockers. Methods All patients admitted or discharged from our institution, the Siyami Ersek Training and Research Hospital, between January 2009 and January 2013 with a diagnosis of AV block were included in the study. Subjects using ophthalmic beta-blockers were recruited and followed for permanent pacemaker requirement during hospitalisation and for three months after discontinuation of the drug. A permanent pacemaker was implanted in patients in whom AV block persisted beyond 72 hours or recurred during the follow-up period. Results A total of 1 122 patients were hospitalised with a diagnosis of AV block and a permanent pacemaker was implanted in 946 cases (84.3%) during the study period. Thirteen patients using ophthalmic beta-blockers for the treatment of glaucoma and no other rate-limiting drugs were included in the study. On electrocardiography, eight patients had complete AV block and five had high-degree AV block. The ophthalmic beta-blockers used were timolol in seven patients (55%), betaxolol in four (30%), and cartelol in two cases (15%). The mean duration of ophthalmic beta-blocker treatment was 30.1 ± 15.9 months. After drug discontinuation, in 10 patients the block persisted and a permanent pacemaker was implanted. During follow up, one more patient required pacemaker implantation. Therefore in total, pacemakers were implanted in 11 out of 13 patients (84.6%). The pacemaker implantation rate did not differ according to the type of topical beta-blocker used (p = 0.37). The presence of infra-nodal block on electrocardiography was associated with higher rates of pacemaker implantation. Conclusion Our results indicate that topical beta-blockers for the treatment of glaucoma may cause severe conduction abnormalities and when AV

  18. An aerodynamic model for one and two degree of freedom wing rock of slender delta wings

    NASA Technical Reports Server (NTRS)

    Hong, John

    1993-01-01

    The unsteady aerodynamic effects due to the separated flow around slender delta wings in motion were analyzed. By combining the unsteady flow field solution with the rigid body Euler equations of motion, self-induced wing rock motion is simulated. The aerodynamic model successfully captures the qualitative characteristics of wing rock observed in experiments. For the one degree of freedom in roll case, the model is used to look into the mechanisms of wing rock and to investigate the effects of various parameters, like angle of attack, yaw angle, displacement of the separation point, and wing inertia. To investigate the roll and yaw coupling for the delta wing, an additional degree of freedom is added. However, no limit cycle was observed in the two degree of freedom case. Nonetheless, the model can be used to apply various control laws to actively control wing rock using, for example, the displacement of the leading edge vortex separation point by inboard span wise blowing.

  19. New Early and Late Carboniferous paleomagnetic results from the Qaidam Block, NW China: Implications for the paleogeography of Central Asia

    NASA Astrophysics Data System (ADS)

    Cao, Yong; Sun, Zhiming; Li, Haibing; Pei, Junling; Xu, Wei; Pan, Jiawei; Zhang, Lei; Ye, Xiaozhou; Huang, Baochun; Wang, Zongxiu

    2017-10-01

    There is an ongoing debate regarding the paleogeographic evolution of the Qaidam Block (37.3 °N/96.4 °E) in northwest China during the late Paleozoic. To provide a reliable constraint on the paleogeographic reconstruction and to determine the relationship with the adjacent area, we performed a paleomagnetic investigation of Early and Late Carboniferous sediments from the Qaidam Block. Stepwise thermal demagnetization successfully isolated high unblocking-temperature characteristic directions from the samples. The tilt-corrected mean direction of the Early Carboniferous sediments is Ds/Is = 298.6°/- 46.4° with α95 = 4.7° and N = 15 sites, corresponding to a paleopole at - 3.2 °N, 147.5 °E with A95 = 4.8°. The Late Carboniferous paleomagnetic direction is Ds/Is = 320.1°/- 46.1° with α95 = 5.3° and N = 8 sites, corresponding to a paleopole at - 15.1 °N, 132.2 °E with A95 = 5.4°. A positive fold test for the Early Carboniferous paleomagnetic directions, and consistency with the Kiaman reversed superchron for the Late Carboniferous paleomagnetic directions, indicates the primary origin of the characteristic remanence of the studied section. The new paleomagnetic results suggest that the Qaidam Block was located at about 27 °N and did not undergo significant N-S movement during the Carboniferous. However, the Qaidam Block experienced a counter-clockwise rotation of about 21° during this period. Comparisons of the paleomagnetic results from the major blocks of Central Asia suggest that the Qaidam Block may have experienced a relatively rapid northward movement and collided with the Tarim Block after the Late Permian. Based on the paleomagnetic poles of the Qaidam Block and adjacent blocks, we present a tentative paleogeographic reconstruction for central Asia during the Early and Late Carboniferous.

  20. 1. Ninth Street (west) facade. Adjacent on the north is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Ninth Street (west) facade. Adjacent on the north is the 9th Street facade of 816 E Street. Both buildings were originally one property. - Riley Building, Rendezvous Adult Magazines & Films, 437 Ninth Street, Northwest, Washington, District of Columbia, DC

  1. Your College Degree: The External Degree Way.

    ERIC Educational Resources Information Center

    Haponski, William C.; And Others

    Information on undertaking an external degree program to obtain a college education is presented. An external degree program is one that has no, or minimal requirements for residence (on-campus attendance). Most often it can be entered at any time of the year and usually grants credit for documented learning already acquired. An external degree…

  2. An interdisciplinary study of the estuarine and coastal oceanography of Block Island Sound and adjacent New York coastal waters

    NASA Technical Reports Server (NTRS)

    Yost, E. F. (Principal Investigator); Hollman, R.; Alexander, J.; Nuzzi, R.

    1974-01-01

    The author has identified the following significant results. Photo-optical additive color quantitative measurements were made of ERTS-1 reprocessed positives of New York Bight and Block Island Sound. Regression of these data on almost simultaneous ship sample data of water's physical, chemical, biological, and optical properties showed that ERTS bands 5 and 6 can be used to predict the absolute value of the total number of particles and bands 4 and 5 to predict the relative extinction coefficient in New York Bight. Water masses and mixing patterns in Block Island Sound heretofore considered transient were found to be persistent phenomena requiring revision of existing mathematical and hydraulic models.

  3. Acidity-promoted cellular uptake and drug release mediated by amine-functionalized block polycarbonates prepared via one-shot ring-opening copolymerization.

    PubMed

    Wang, Hua-Fen; Jia, Hui-Zhen; Chu, Yan-Feng; Feng, Jun; Zhang, Xian-Zheng; Zhuo, Ren-Xi

    2014-04-01

    This paper reports a drug nanovehicle self-assembled from an amine-functionalized block copolymer poly(6,14-dimethyl-1,3,9,11-tetraoxa-6,14-diaza-cyclohexadecane-2,10-dione)-block-poly(1,3-dioxepan-2-one) (PADMC-b-PTeMC), which is prepared by controlable ring-opening block copolymerization attractively in a "one-shot feeding" pathway. The copolymers display high cell-biocompatibility with no apparent cytotoxicities detected in 293T and HeLa cells. Due to their amphiphilic nature, PADMC-b-PTeMC copolymers can self-assemble into nanosized micelles capable of loading anticancer drugs such as camptothecin (CPT) and doxorubicin (DOX). In particular, the outer PADMC shell endows the PADMC-b-PTeMC nanomicelles with pH-dependent control over the micellar morphology, cell uptake efficiency, and the drug release pattern. Confocal inspection reveals the remarkably enhanced cellular internalization of drug loaded micelles by cancerous HeLa cells at relatively lower pH 5.8 simulating the mildly acid microenvironment in tumors. Along with the acidity-triggered volume expansion of micelles, an accelerated CPT release in vitro occurs. The obtained results adumbrate the possibility of completely biodegradable PADMC-b-PTeMC as pH-sensitive drug carriers for tumor chemotherapy. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. An electrostatic Particle-In-Cell code on multi-block structured meshes

    NASA Astrophysics Data System (ADS)

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; Vernon, Louis J.; Moulton, J. David

    2017-12-01

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. Despite the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where an arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma-material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. Compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.

  5. An electrostatic Particle-In-Cell code on multi-block structured meshes

    DOE PAGES

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; ...

    2017-09-14

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

  6. An electrostatic Particle-In-Cell code on multi-block structured meshes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

  7. Stress field rotation or block rotation: An example from the Lake Mead fault system

    NASA Technical Reports Server (NTRS)

    Ron, Hagai; Nur, Amos; Aydin, Atilla

    1990-01-01

    The Coulomb criterion, as applied by Anderson (1951), has been widely used as the basis for inferring paleostresses from in situ fault slip data, assuming that faults are optimally oriented relative to the tectonic stress direction. Consequently if stress direction is fixed during deformation so must be the faults. Freund (1974) has shown that faults, when arranged in sets, must generally rotate as they slip. Nur et al., (1986) showed how sufficiently large rotations require the development of new sets of faults which are more favorably oriented to the principal direction of stress. This leads to the appearance of multiple fault sets in which older faults are offset by younger ones, both having the same sense of slip. Consequently correct paleostress analysis must include the possible effect of fault and material rotation, in addition to stress field rotation. The combined effects of stress field rotation and material rotation were investigated in the Lake Meade Fault System (LMFS) especially in the Hoover Dam area. Fault inversion results imply an apparent 60 degrees clockwise (CW) rotation of the stress field since mid-Miocene time. In contrast structural data from the rest of the Great Basin suggest only a 30 degrees CW stress field rotation. By incorporating paleomagnetic and seismic evidence, the 30 degrees discrepancy can be neatly resolved. Based on paleomagnetic declination anomalies, it is inferred that slip on NW trending right lateral faults caused a local 30 degrees counter-clockwise (CCW) rotation of blocks and faults in the Lake Mead area. Consequently the inferred 60 degrees CW rotation of the stress field in the LMFS consists of an actual 30 degrees CW rotation of the stress field (as for the entire Great Basin) plus a local 30 degrees CCW material rotation of the LMFS fault blocks.

  8. Stress field rotation or block rotation: An example from the Lake Mead fault system

    NASA Astrophysics Data System (ADS)

    Ron, Hagai; Nur, Amos; Aydin, Atilla

    1990-02-01

    The Coulomb criterion, as applied by Anderson (1951), has been widely used as the basis for inferring paleostresses from in situ fault slip data, assuming that faults are optimally oriented relative to the tectonic stress direction. Consequently if stress direction is fixed during deformation so must be the faults. Freund (1974) has shown that faults, when arranged in sets, must generally rotate as they slip. Nur et al., (1986) showed how sufficiently large rotations require the development of new sets of faults which are more favorably oriented to the principal direction of stress. This leads to the appearance of multiple fault sets in which older faults are offset by younger ones, both having the same sense of slip. Consequently correct paleostress analysis must include the possible effect of fault and material rotation, in addition to stress field rotation. The combined effects of stress field rotation and material rotation were investigated in the Lake Meade Fault System (LMFS) especially in the Hoover Dam area. Fault inversion results imply an apparent 60 degrees clockwise (CW) rotation of the stress field since mid-Miocene time. In contrast structural data from the rest of the Great Basin suggest only a 30 degrees CW stress field rotation. By incorporating paleomagnetic and seismic evidence, the 30 degrees discrepancy can be neatly resolved. Based on paleomagnetic declination anomalies, it is inferred that slip on NW trending right lateral faults caused a local 30 degrees counter-clockwise (CCW) rotation of blocks and faults in the Lake Mead area. Consequently the inferred 60 degrees CW rotation of the stress field in the LMFS consists of an actual 30 degrees CW rotation of the stress field (as for the entire Great Basin) plus a local 30 degrees CCW material rotation of the LMFS fault blocks.

  9. Thermal blocking of preheating

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lerner, Rose; Tranberg, Anders, E-mail: rose.lerner@desy.de, E-mail: anders.tranberg@uis.no

    2015-04-01

    The parametric resonance responsible for preheating after inflation will end when self-interactions of the resonating field and interactions of this field with secondary degrees of freedom become important. In many cases, the effect may be quantified in terms of an effective mass and the resulting shifting out of the spectrum of the strongest resonance band. In certain curvaton models, such thermal blocking can even occur before preheating has begun, delaying or even preventing the decay of the curvaton. We investigate numerically to what extent this thermal blocking is realised in a specific scenario, and whether the effective mass is wellmore » approximated by the perturbative leading order thermal mass. We find that the qualitative behaviour is well reproduced in this approximation, and that the end of preheating can be confidently estimated.« less

  10. Effects of Grafting Density on Block Polymer Self-Assembly: From Linear to Bottlebrush

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, Tzu-Pin; Chang, Alice B.; Luo, Shao-Xiong

    Grafting density is an important structural parameter that imparts significant influences over the physical properties of architecturally complex polymers. In this paper, the physical consequences of varying the grafting density (z) were studied in the context of block polymer self-assembly. Well-defined block polymers spanning the linear, comb, and bottlebrush regimes (0 ≤ z ≤ 1) were prepared via grafting-through ring-opening-metathesis polymerization (ROMP). ω-norbornenyl poly(D,L-lactide) (PLA) and polystyrene (PS) macromonomers were copolymerized with discrete co-monomers in different feed ratios, enabling precise control over the grafting density. Small-angle X-ray scattering (SAXS) experiments demonstrate that these graft block polymers can self-assemble into long-range-orderedmore » lamellar structures. For seventeen series of block polymers with variable z, the scaling of the lamellar period with the total backbone degree of polymerization (d* ~ N bb α) was studied. The scaling exponent α monotonically decreases with decreasing z and exhibits an apparent transition at z ≈ 0.2, suggesting significant changes in the chain conformations. Comparison of two block polymer systems, one that is strongly segregated for all z (System I) and one that experiences weak segregation at low z (System II), indicates that the observed trends are primarily caused by the polymer architectures, instead of segregation strengths. A model is pro-posed in which the characteristic ratio (C ∞), a proxy for the backbone stiffness, scales with N bb as a function of the grafting density: C ∞ ~ N bb f(z). To the best of our knowledge, this report represents the first study of scaling behavior for the self-assembly of block polymers with variable grafting density. Lastly, the relationships disclosed herein provide valuable insights into conformational changes with grafting density, thus introducing new opportunities for future block polymer design.« less

  11. Effects of Grafting Density on Block Polymer Self-Assembly: From Linear to Bottlebrush

    DOE PAGES

    Lin, Tzu-Pin; Chang, Alice B.; Luo, Shao-Xiong; ...

    2017-10-26

    Grafting density is an important structural parameter that imparts significant influences over the physical properties of architecturally complex polymers. In this paper, the physical consequences of varying the grafting density (z) were studied in the context of block polymer self-assembly. Well-defined block polymers spanning the linear, comb, and bottlebrush regimes (0 ≤ z ≤ 1) were prepared via grafting-through ring-opening-metathesis polymerization (ROMP). ω-norbornenyl poly(D,L-lactide) (PLA) and polystyrene (PS) macromonomers were copolymerized with discrete co-monomers in different feed ratios, enabling precise control over the grafting density. Small-angle X-ray scattering (SAXS) experiments demonstrate that these graft block polymers can self-assemble into long-range-orderedmore » lamellar structures. For seventeen series of block polymers with variable z, the scaling of the lamellar period with the total backbone degree of polymerization (d* ~ N bb α) was studied. The scaling exponent α monotonically decreases with decreasing z and exhibits an apparent transition at z ≈ 0.2, suggesting significant changes in the chain conformations. Comparison of two block polymer systems, one that is strongly segregated for all z (System I) and one that experiences weak segregation at low z (System II), indicates that the observed trends are primarily caused by the polymer architectures, instead of segregation strengths. A model is pro-posed in which the characteristic ratio (C ∞), a proxy for the backbone stiffness, scales with N bb as a function of the grafting density: C ∞ ~ N bb f(z). To the best of our knowledge, this report represents the first study of scaling behavior for the self-assembly of block polymers with variable grafting density. Lastly, the relationships disclosed herein provide valuable insights into conformational changes with grafting density, thus introducing new opportunities for future block polymer design.« less

  12. Replacement of Fine Aggregate by using Recyclable Materials in Paving Blocks

    NASA Astrophysics Data System (ADS)

    Koganti, Shyam Prakash; Hemanthraja, Kommineni; Sajja, Satish

    2017-08-01

    Cement concrete paving blocks are precast hard products complete out of cement concrete. The product is made in various sizes and shapes like square, round and rectangular blocks of different dimensions with designs for interlocking of adjacent tiles blocks. Several Research Works have been carried out in the past to study the possibility of utilizing waste materials and industrial byproducts in the manufacturing of paver blocks. Various industrial waste materials like quarry dust, glass powder, ceramic dust and coal dust are used as partial replacement of fine aggregate and assessed the strength parameters and compared the profit percentages after replacement with waste materials. Quarry dust can be replaced by 20% and beyond that the difference in strength is not much higher but considering cost we can replace upto 40% so that we can get a profit of almost 10%. Similarly we can replace glass powder and ceramic dust by 20% only beyond that there is decrement in strength and even with 20% replacement we can get 1.34 % and 2.42% of profit. Coal dust is not suitable for alternative material as fine aggregate as it reduces the strength.

  13. Effects of Grafting Density on Block Polymer Self-Assembly: From Linear to Bottlebrush.

    PubMed

    Lin, Tzu-Pin; Chang, Alice B; Luo, Shao-Xiong; Chen, Hsiang-Yun; Lee, Byeongdu; Grubbs, Robert H

    2017-11-28

    Grafting density is an important structural parameter that exerts significant influences over the physical properties of architecturally complex polymers. In this report, the physical consequences of varying the grafting density (z) were studied in the context of block polymer self-assembly. Well-defined block polymers spanning the linear, comb, and bottlebrush regimes (0 ≤ z ≤ 1) were prepared via grafting-through ring-opening-metathesis polymerization. ω-Norbornenyl poly(d,l-lactide) and polystyrene macromonomers were copolymerized with discrete comonomers in different feed ratios, enabling precise control over both the grafting density and molecular weight. Small-angle X-ray scattering experiments demonstrate that these graft block polymers self-assemble into long-range-ordered lamellar structures. For 17 series of block polymers with variable z, the scaling of the lamellar period with the total backbone degree of polymerization (d* ∼ N bb α ) was studied. The scaling exponent α monotonically decreases with decreasing z and exhibits an apparent transition at z ≈ 0.2, suggesting significant changes in the chain conformations. Comparison of two block polymer systems, one that is strongly segregated for all z (System I) and one that experiences weak segregation at low z (System II), indicates that the observed trends are primarily caused by the polymer architectures, not segregation effects. A model is proposed in which the characteristic ratio (C ∞ ), a proxy for the backbone stiffness, scales with N bb as a function of the grafting density: C ∞ ∼ N bb f(z) . The scaling behavior disclosed herein provides valuable insights into conformational changes with grafting density, thus introducing opportunities for block polymer and material design.

  14. Adjacent segment infection after surgical treatment of spondylodiscitis.

    PubMed

    Siam, Ahmed Ezzat; El Saghir, Hesham; Boehm, Heinrich

    2016-03-01

    This is the first case series to describe adjacent segment infection (ASI) after surgical treatment of spondylodiscitis (SD). Patients with SD, spondylitis who were surgically treated between 1994 and 2012 were included. Out of 1187 cases, 23 (1.94 %) returned to our institution (Zentralklinik Bad Berka) with ASI: 10 males, 13 females, with a mean age of 65.1 years and a mean follow-up of 69 months. ASI most commonly involved L3-4 (seven patients), T12-L1 (five) and L2-3 (four). The mean interval between operations of primary infection and ASI was 36.9 months. All cases needed surgical intervention, debridement, reconstruction and fusion with longer instrumentation, with culture and sensitivity-based postoperative antimicrobial therapy. At last follow-up, six patients (26.1 %) were mobilized in a wheelchair with a varying degree of paraplegia (three had pre-existing paralysis). Three patients died within 2 months after the ASI operation (13 %). Excellent outcomes were achieved in five patients, and good in eight. Adjacent segment infection after surgical treatment of spondylodiscitis is a rare complication (1.94 %). It is associated with multimorbidity and shows a high mortality rate and a high neurological affection rate. Possible explanations are: haematomas of repeated micro-fractures around screw loosening, haematogenous spread, direct inoculation or a combination of these factors. ASI may also lead to proximal junctional kyphosis, as found in this series. We suggest early surgical intervention with anterior debridement, reconstruction and fusion with posterior instrumentation, followed by antimicrobial therapy for 12 weeks. Level IV retrospective uncontrolled case series.

  15. Processing multiple non-adjacent dependencies: evidence from sequence learning

    PubMed Central

    de Vries, Meinou H.; Petersson, Karl Magnus; Geukes, Sebastian; Zwitserlood, Pienie; Christiansen, Morten H.

    2012-01-01

    Processing non-adjacent dependencies is considered to be one of the hallmarks of human language. Assuming that sequence-learning tasks provide a useful way to tap natural-language-processing mechanisms, we cross-modally combined serial reaction time and artificial-grammar learning paradigms to investigate the processing of multiple nested (A1A2A3B3B2B1) and crossed dependencies (A1A2A3B1B2B3), containing either three or two dependencies. Both reaction times and prediction errors highlighted problems with processing the middle dependency in nested structures (A1A2A3B3_B1), reminiscent of the ‘missing-verb effect’ observed in English and French, but not with crossed structures (A1A2A3B1_B3). Prior linguistic experience did not play a major role: native speakers of German and Dutch—which permit nested and crossed dependencies, respectively—showed a similar pattern of results for sequences with three dependencies. As for sequences with two dependencies, reaction times and prediction errors were similar for both nested and crossed dependencies. The results suggest that constraints on the processing of multiple non-adjacent dependencies are determined by the specific ordering of the non-adjacent dependencies (i.e. nested or crossed), as well as the number of non-adjacent dependencies to be resolved (i.e. two or three). Furthermore, these constraints may not be specific to language but instead derive from limitations on structured sequence learning. PMID:22688641

  16. Non-Linear Material Three Degree of Freedom Analysis of Submarine Drydock Blocking System

    DTIC Science & Technology

    1988-05-01

    drydock blocking materials laminates should be used. For example, if laminated oak timbers are judged to be suitable they would exhibit a minimum of...1/4 of the strength variation of solid timbers . They would not have the inherent defects of large sawn timbers such as grain slope, checks, shakes ,and...experiments on this concept have been carried out over the last few years using the shaking table at the Earthquake Engineering Research Center

  17. Periodic nanostructures from self assembled wedge-type block-copolymers

    DOEpatents

    Xia, Yan; Sveinbjornsson, Benjamin R.; Grubbs, Robert H.; Weitekamp, Raymond; Miyake, Garret M.; Piunova, Victoria; Daeffler, Christopher Scot

    2015-06-02

    The invention provides a class of wedge-type block copolymers having a plurality of chemically different blocks, at least a portion of which incorporates a wedge group-containing block providing useful properties. For example, use of one or more wedge group-containing blocks in some block copolymers of the invention significantly inhibits chain entanglement and, thus, the present block copolymers materials provide a class of polymer materials capable of efficient molecular self-assembly to generate a range of structures, such as periodic nanostructures and microstructures. Materials of the present invention include copolymers having one or more wedge group-containing blocks, and optionally for some applications copolymers also incorporating one or more polymer side group-containing blocks. The present invention also provides useful methods of making and using wedge-type block copolymers.

  18. Novel modes and adaptive block scanning order for intra prediction in AV1

    NASA Astrophysics Data System (ADS)

    Hadar, Ofer; Shleifer, Ariel; Mukherjee, Debargha; Joshi, Urvang; Mazar, Itai; Yuzvinsky, Michael; Tavor, Nitzan; Itzhak, Nati; Birman, Raz

    2017-09-01

    The demand for streaming video content is on the rise and growing exponentially. Networks bandwidth is very costly and therefore there is a constant effort to improve video compression rates and enable the sending of reduced data volumes while retaining quality of experience (QoE). One basic feature that utilizes the spatial correlation of pixels for video compression is Intra-Prediction, which determines the codec's compression efficiency. Intra prediction enables significant reduction of the Intra-Frame (I frame) size and, therefore, contributes to efficient exploitation of bandwidth. In this presentation, we propose new Intra-Prediction algorithms that improve the AV1 prediction model and provide better compression ratios. Two (2) types of methods are considered: )1( New scanning order method that maximizes spatial correlation in order to reduce prediction error; and )2( New Intra-Prediction modes implementation in AVI. Modern video coding standards, including AVI codec, utilize fixed scan orders in processing blocks during intra coding. The fixed scan orders typically result in residual blocks with high prediction error mainly in blocks with edges. This means that the fixed scan orders cannot fully exploit the content-adaptive spatial correlations between adjacent blocks, thus the bitrate after compression tends to be large. To reduce the bitrate induced by inaccurate intra prediction, the proposed approach adaptively chooses the scanning order of blocks according to criteria of firstly predicting blocks with maximum number of surrounding, already Inter-Predicted blocks. Using the modified scanning order method and the new modes has reduced the MSE by up to five (5) times when compared to conventional TM mode / Raster scan and up to two (2) times when compared to conventional CALIC mode / Raster scan, depending on the image characteristics (which determines the percentage of blocks predicted with Inter-Prediction, which in turn impacts the efficiency of the new

  19. Periodontal regenerative effect of a bovine hydroxyapatite/collagen block in one-wall intrabony defects in dogs: a histometric analysis

    PubMed Central

    Jung, Ui-Won; Lee, Jung-Seok; Park, Weon-Yeong; Cha, Jae-Kook; Hwang, Ji-Wan; Park, Jung-Chul; Kim, Chang-Sung; Cho, Kyoo-Sung; Chai, Jung-Kiu

    2011-01-01

    Purpose The aim of this study was to elucidate the effect of a bovine hydroxyapatite/collagen (BHC) block in one-wall intrabony periodontal defects in dogs. Methods A one-wall intrabony periodontal defect (4 mm wide and 5 mm deep) was prepared bilaterally at the mesial side of the mandibular fourth premolar in five beagle dogs. After thorough root planing, block-type BHC (4×5×5 mm) was placed on one side. The contralateral defect area did not receive any material as a sham-surgery control. Histological analysis of the sites was performed after an 8-week healing period. Results Two of five samples in the experimental group healed well without dissipation of the graft materials, and histological analysis revealed excellent regeneration of the periodontal tissues. However, most of the grafted materials had been displaced in the other three samples, leaving only a small portion of the graft. The measured parameters exhibited large standard deviations, and the mean values did not differ significantly between the experimental and sham-surgery control sides. Conclusions The application of BHC alone-without a barrier membrane-to wide, one-wall intrabony periodontal defects yielded inconsistent results regarding both periodontal regeneration and substantivity of the graft materials. Thus, the use of a barrier membrane for noncontained-type defects is recommended to improve the stability of the grafted material, and to condense it. PMID:22324006

  20. 49 CFR 236.827 - System, block signal.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false System, block signal. 236.827 Section 236.827... System, block signal. A method of governing the movement of trains into or within one or more blocks by block signals or cab signals. ...

  1. Response Surface Analysis of Experiments with Random Blocks

    DTIC Science & Technology

    1988-09-01

    partitioned into a lack of fit sum of squares, SSLOF, and a pure error sum of squares, SSPE . The latter is obtained by pooling the pure error sums of squares...from the blocks. Tests concerning the polynomial effects can then proceed using SSPE as the error term in the denominators of the F test statistics. 3.2...the center point in each of the three blocks is equal to SSPE = 2.0127 with 5 degrees of freedom. Hence, the lack of fit sum of squares is SSLoF

  2. Bullet-Block Science Video Puzzle

    ERIC Educational Resources Information Center

    Shakur, Asif

    2015-01-01

    A science video blog, which has gone viral, shows a wooden block shot by a vertically aimed rifle. The video shows that the block hit dead center goes exactly as high as the one shot off-center. (Fig. 1). The puzzle is that the block shot off-center carries rotational kinetic energy in addition to the gravitational potential energy. This leads a…

  3. Colostomy with Transversus Abdominis Plane Block

    PubMed Central

    Tekelioğlu, Ümit Yaşar; Demirhan, Abdullah; Şit, Mustafa; Kurt, Adem Deniz; Bilgi, Murat; Koçoğlu, Hasan

    2015-01-01

    Transversus abdominis plane (TAP) block is one of the abdominal field block. The TAP block is used for both anaesthetic management and post-operative pain therapy in lower abdominal surgery. TAP block is a procedure in which local anaesthetic agents are applied to the anatomic neurofacial space between the internal oblique and the transversus abdominis muscle. TAP block is a good method for post-operative pain control as well as allows for short operations involving the abdominal area. In this article, a case of colostomy under TAP block is presented. PMID:27366540

  4. Long-Term Follow-Up of Children with Heart Block Born from Mothers with Systemic Lupus Erythematosus: A Retrospective Study from the Database Pediatric and Congenital Heart Disease in University Hospitals Leuven.

    PubMed

    DE Caluwé, Eva; VAN DE Bruaene, Alexander; Willems, Rik; Troost, Els; Gewillig, Marc; Rega, Filip; Budts, Werner

    2016-09-01

    Children from mothers with systemic lupus erythematosus are frequently born with congenital heart block. This study aimed at evaluating long-term outcome because long-term data are scarce. In the database of pediatric and congenital heart disease (University Hospitals Leuven), 19 children from systemic lupus erythematosus mothers and who were born with or developed atrioventricular block were identified. All records were reviewed for disease course and outcome. Median follow-up time was 7 years (interquartile ranges [IQR] 4.5-13 years). One child had no heart block at birth and developed only a first-degree block during follow-up. One had a second-degree heart block and developed a complete heart block. Seventeen patients (89%) were born with a complete heart block. Seventeen patients (89%) needed a definitive pacemaker. In all, epicardial leads were used at first implantation. Eighty-two percent received their pacemaker in the first year of life. The first battery had a median lifetime of 5 years (IQR 3.5-5 years), the second 6 years (IQR 4.5-6.3 years), and the third 5 years (IQR 5-6 years). Note that 47% of patients needed a lead replacement due to lead problems. Only one pericardial tamponade after pacemaker implantation. No device or lead infections occurred. The left ventricular systolic function at latest follow-up was normal for all. No patients died. In children with heart block born from systemic lupus erythematosus mothers, an early need for pacemaker implantation was documented. The overall battery life was acceptable, but there was a high need for lead replacement. Complication rate was low. Late outcome was good. © 2016 Wiley Periodicals, Inc.

  5. One-step formation of w/o/w multiple emulsions stabilized by single amphiphilic block copolymers.

    PubMed

    Hong, Liangzhi; Sun, Guanqing; Cai, Jinge; Ngai, To

    2012-02-07

    Multiple emulsions are complex polydispersed systems in which both oil-in-water (O/W) and water-in-oil (W/O) emulsion exists simultaneously. They are often prepared accroding to a two-step process and commonly stabilized using a combination of hydrophilic and hydrophobic surfactants. Recently, some reports have shown that multiple emulsions can also be produced through one-step method with simultaneous occurrence of catastrophic and transitional phase inversions. However, these reported multiple emulsions need surfactant blends and are usually described as transitory or temporary systems. Herein, we report a one-step phase inversion process to produce water-in-oil-in-water (W/O/W) multiple emulsions stabilized solely by a synthetic diblock copolymer. Unlike the use of small molecule surfactant combinations, block copolymer stabilized multiple emulsions are remarkably stable and show the ability to separately encapsulate both polar and nonpolar cargos. The importance of the conformation of the copolymer surfactant at the interfaces with regards to the stability of the multiple emulsions using the one-step method is discussed.

  6. 47 CFR 101.1421 - Coordination of adjacent area MVDDS stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Multichannel Video Distribution and Data Service Rules for... compatible with adjacent and co-channel operations in the adjacent areas on all its frequencies; and (2... adjacent and co-channel operations in adjacent areas. (b) Harmful interference to public safety stations...

  7. LDPC Codes with Minimum Distance Proportional to Block Size

    NASA Technical Reports Server (NTRS)

    Divsalar, Dariush; Jones, Christopher; Dolinar, Samuel; Thorpe, Jeremy

    2009-01-01

    Low-density parity-check (LDPC) codes characterized by minimum Hamming distances proportional to block sizes have been demonstrated. Like the codes mentioned in the immediately preceding article, the present codes are error-correcting codes suitable for use in a variety of wireless data-communication systems that include noisy channels. The previously mentioned codes have low decoding thresholds and reasonably low error floors. However, the minimum Hamming distances of those codes do not grow linearly with code-block sizes. Codes that have this minimum-distance property exhibit very low error floors. Examples of such codes include regular LDPC codes with variable degrees of at least 3. Unfortunately, the decoding thresholds of regular LDPC codes are high. Hence, there is a need for LDPC codes characterized by both low decoding thresholds and, in order to obtain acceptably low error floors, minimum Hamming distances that are proportional to code-block sizes. The present codes were developed to satisfy this need. The minimum Hamming distances of the present codes have been shown, through consideration of ensemble-average weight enumerators, to be proportional to code block sizes. As in the cases of irregular ensembles, the properties of these codes are sensitive to the proportion of degree-2 variable nodes. A code having too few such nodes tends to have an iterative decoding threshold that is far from the capacity threshold. A code having too many such nodes tends not to exhibit a minimum distance that is proportional to block size. Results of computational simulations have shown that the decoding thresholds of codes of the present type are lower than those of regular LDPC codes. Included in the simulations were a few examples from a family of codes characterized by rates ranging from low to high and by thresholds that adhere closely to their respective channel capacity thresholds; the simulation results from these examples showed that the codes in question have low

  8. INFERENCE BUILDING BLOCKS

    DTIC Science & Technology

    2018-02-15

    address the problem that probabilistic inference algorithms are diÿcult and tedious to implement, by expressing them in terms of a small number of...building blocks, which are automatic transformations on probabilistic programs. On one hand, our curation of these building blocks reflects the way human...reasoning with low-level computational optimization, so the speed and accuracy of the generated solvers are competitive with state-of-the-art systems. 15

  9. Marketing Program Outcomes: The Building Blocks of an Associate Degree Marketing Program.

    ERIC Educational Resources Information Center

    Ruhland, Sheila; Samson, Harland; Brewer, Jerrilyn; Hague, David

    This document contains materials about and from an assessment of Wisconsin's associate degree marketing program. The document begins with a report containing the following: marketing program mission and vision statements; overview, conclusions, and recommendations of an assessment of marketing education needs in which recent graduates of the…

  10. Coastal protection using topological interlocking blocks

    NASA Astrophysics Data System (ADS)

    Pasternak, Elena; Dyskin, Arcady; Pattiaratchi, Charitha; Pelinovsky, Efim

    2013-04-01

    The coastal protection systems mainly rely on the self-weight of armour blocks to ensure its stability. We propose a system of interlocking armour blocks, which form plate-shape assemblies. The shape and the position of the blocks are chosen in such a way as to impose kinematic constraints that prevent the blocks from being removed from the assembly. The topological interlocking shapes include simple convex blocks such as platonic solids, the most practical being tetrahedra, cubes and octahedra. Another class of topological interlocking blocks is so-called osteomorphic blocks, which form plate-like assemblies tolerant to random block removal (almost 25% of blocks need to be removed for the assembly to loose integrity). Both classes require peripheral constraint, which can be provided either by the weight of the blocks or post-tensioned internal cables. The interlocking assemblies provide increased stability because lifting one block involves lifting (and bending) the whole assembly. We model the effect of interlocking by introducing an equivalent additional self-weight of the armour blocks. This additional self-weight is proportional to the critical pressure needed to cause bending of the interlocking assembly when it loses stability. Using beam approximation we find an equivalent stability coefficient for interlocking. It is found to be greater than the stability coefficient of a structure with similar blocks without interlocking. In the case when the peripheral constraint is provided by the weight of the blocks and for the slope angle of 45o, the effective stability coefficient for a structure of 100 blocks is 33% higher than the one for a similar structure without interlocking. Further increase in the stability coefficient can be reached by a specially constructed peripheral constraint system, for instance by using post-tension cables.

  11. 78 FR 1938 - Unblocking of One Individual and One Entity Blocked Pursuant to Executive Order 13315 of August...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... list of Specially Designated Nationals and Blocked Persons (``SDN List''). DATES: The removal of the individual and entity from the SDN List is effective as of January 3, 2013. FOR FURTHER INFORMATION CONTACT... entity should be removed from the SDN List: Individual 1. SPECKMAN, Jeanine, United Kingdom (individual...

  12. Distribution of short block copolymer chains in Binary Blends of Block Copolymers Having Hydrogen Bonding

    NASA Astrophysics Data System (ADS)

    Kwak, Jongheon; Han, Sunghyun; Kim, Jin Kon

    2014-03-01

    A binary mixture of two block copolymers whose blocks are capable of forming the hydrogen bonding allows one to obtain various microdomains that could not be expected for neat block copolymer. For instance, the binary blend of symmetric polystyrene-block-poly(2-vinylpyridine) copolymer (PS-b-P2VP) and polystyrene-block-polyhydroxystyrene copolymer (PS-b-PHS) blends where the hydrogen bonding occurred between P2VP and PHS showed hexagonally packed (HEX) cylindrical and body centered cubic (BCC) spherical microdomains. To know the exact location of short block copolymer chains at the interface, we synthesized deuterated polystyrene-block-polyhydroxystyrene copolymer (dPS-b-PHS) and prepared a binary mixture with PS-b-P2VP. We investigate, via small angle X-ray scattering (SAXS) and neutron reflectivity (NR), the exact location of shorter dPS block chain near the interface of the microdomains.

  13. Block Copolymer Nanocomposites with High Refractive Index Contrast for One-Step Photonics.

    PubMed

    Song, Dong-Po; Li, Cheng; Li, Wenhao; Watkins, James J

    2016-01-26

    Photonic crystals (PhCs) prepared using the self-assembly of block copolymers (BCPs) offer the potential for simple and rapid device fabrication but typically suffer from low refractive index contrast (Δn ≤ 0.1) between the phase-segregated domains. Here, we report the simple fabrication of BCP-based photonic nanocomposites with large differences in refractive index (Δn > 0.27). Zirconium oxide (ZrO2) nanoparticles coated with gallic acid are used to tune the optical constants of the target domains of self-assembled (polynorbornene-graft-poly(tert-butyl acrylate))-block-(polynorbornene-graft-poly(ethylene oxide)) (PtBA-b-PEO) brush block copolymers (BBCPs). Strong hydrogen-bonding interactions between the ligands on ZrO2 and PEO brushes of the BBCPs enable selective incorporation and high loading of up to 70 wt % (42 vol %) of the ZrO2 nanoparticles within the PEO domain, resulting in a significant increase of refractive index from 1.45 to up to 1.70. Consequently, greatly enhanced reflection at approximately 398 nm (increases of ∼250%) was observed for the photonic nanocomposites (domain spacing = 137 nm) relative to that of the unmodified BBCPs, which is consistent with numeric modeling results using transfer matrix methods. This work provides a simple strategy for a wide range tuning of optical constants of BCP domains, thereby enabling the design and creation of high-performance photonic coatings for various applications. The large refractive index contrast enables high reflectivity while simultaneously reducing the coating thickness necessary, compared to pure BCP systems.

  14. Structure and Dynamics of Ionic Block Copolymer Melts: Computational Study

    DOE PAGES

    Aryal, Dipak; Agrawal, Anupriya; Perahia, Dvora; ...

    2017-09-06

    Structure and dynamics of melts of copolymers with an ABCBA topology, where C is an ionizable block, have been studied by fully atomistic molecular dynamics (MD) simulations. Introducing an ionizable block for functionality adds a significant element to the coupled set of interactions that determine the structure and dynamics of the macromolecule. The polymer consists of a randomly sulfonated polystyrene C block tethered to a flexible poly(ethylene-r-propylene) bridge B and end-capped with poly(tert-butylstyrene) A. The chemical structure and topology of these polymers constitute a model for incorporation of ionic blocks within a framework that provides tactility and mechanical stability. Heremore » in this paper we resolve the structure and dynamics of a structured polymer on the nanoscale constrained by ionic clusters. We find that the melts form intertwined networks of the A and C blocks independent of the degree of sulfonation of the C block with no long-range order. The cluster cohesiveness and morphology affect both macroscopic translational motion and segmental dynamics of all the blocks.« less

  15. Structure and Dynamics of Ionic Block Copolymer Melts: Computational Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aryal, Dipak; Agrawal, Anupriya; Perahia, Dvora

    Structure and dynamics of melts of copolymers with an ABCBA topology, where C is an ionizable block, have been studied by fully atomistic molecular dynamics (MD) simulations. Introducing an ionizable block for functionality adds a significant element to the coupled set of interactions that determine the structure and dynamics of the macromolecule. The polymer consists of a randomly sulfonated polystyrene C block tethered to a flexible poly(ethylene-r-propylene) bridge B and end-capped with poly(tert-butylstyrene) A. The chemical structure and topology of these polymers constitute a model for incorporation of ionic blocks within a framework that provides tactility and mechanical stability. Heremore » in this paper we resolve the structure and dynamics of a structured polymer on the nanoscale constrained by ionic clusters. We find that the melts form intertwined networks of the A and C blocks independent of the degree of sulfonation of the C block with no long-range order. The cluster cohesiveness and morphology affect both macroscopic translational motion and segmental dynamics of all the blocks.« less

  16. 33 CFR 80.1395 - Puget Sound and adjacent waters.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Puget Sound and adjacent waters... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1395 Puget Sound and adjacent waters. The 72 COLREGS shall apply on all waters of Puget Sound and adjacent waters, including Lake Union...

  17. 33 CFR 80.1395 - Puget Sound and adjacent waters.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Puget Sound and adjacent waters... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1395 Puget Sound and adjacent waters. The 72 COLREGS shall apply on all waters of Puget Sound and adjacent waters, including Lake Union...

  18. 33 CFR 80.1395 - Puget Sound and adjacent waters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Puget Sound and adjacent waters... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1395 Puget Sound and adjacent waters. The 72 COLREGS shall apply on all waters of Puget Sound and adjacent waters, including Lake Union...

  19. 33 CFR 80.1395 - Puget Sound and adjacent waters.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Puget Sound and adjacent waters... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1395 Puget Sound and adjacent waters. The 72 COLREGS shall apply on all waters of Puget Sound and adjacent waters, including Lake Union...

  20. 33 CFR 80.1395 - Puget Sound and adjacent waters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Puget Sound and adjacent waters... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1395 Puget Sound and adjacent waters. The 72 COLREGS shall apply on all waters of Puget Sound and adjacent waters, including Lake Union...

  1. Alumni from One External Degree Program: Profile, Perceptions, and Preference.

    ERIC Educational Resources Information Center

    Firenze, Louis

    1983-01-01

    The importance to alumni of a nontraditional program and the negotiability of the degree to the alumni, their employers and peers, and graduate schools was examined. Data indicated that the main reasons for selecting a nontraditional program were a flexible schedule and the need to maintain a regular working day. (Author/MLW)

  2. Intra prediction using face continuity in 360-degree video coding

    NASA Astrophysics Data System (ADS)

    Hanhart, Philippe; He, Yuwen; Ye, Yan

    2017-09-01

    This paper presents a new reference sample derivation method for intra prediction in 360-degree video coding. Unlike the conventional reference sample derivation method for 2D video coding, which uses the samples located directly above and on the left of the current block, the proposed method considers the spherical nature of 360-degree video when deriving reference samples located outside the current face to which the block belongs, and derives reference samples that are geometric neighbors on the sphere. The proposed reference sample derivation method was implemented in the Joint Exploration Model 3.0 (JEM-3.0) for the cubemap projection format. Simulation results for the all intra configuration show that, when compared with the conventional reference sample derivation method, the proposed method gives, on average, luma BD-rate reduction of 0.3% in terms of the weighted spherical PSNR (WS-PSNR) and spherical PSNR (SPSNR) metrics.

  3. Eigenvalue routines in NASTRAN: A comparison with the Block Lanczos method

    NASA Technical Reports Server (NTRS)

    Tischler, V. A.; Venkayya, Vipperla B.

    1993-01-01

    The NASA STRuctural ANalysis (NASTRAN) program is one of the most extensively used engineering applications software in the world. It contains a wealth of matrix operations and numerical solution techniques, and they were used to construct efficient eigenvalue routines. The purpose of this paper is to examine the current eigenvalue routines in NASTRAN and to make efficiency comparisons with a more recent implementation of the Block Lanczos algorithm by Boeing Computer Services (BCS). This eigenvalue routine is now available in the BCS mathematics library as well as in several commercial versions of NASTRAN. In addition, CRAY maintains a modified version of this routine on their network. Several example problems, with a varying number of degrees of freedom, were selected primarily for efficiency bench-marking. Accuracy is not an issue, because they all gave comparable results. The Block Lanczos algorithm was found to be extremely efficient, in particular, for very large size problems.

  4. Mass counts: ERP correlates of non-adjacent dependency learning under different exposure conditions.

    PubMed

    Citron, Francesca M M; Oberecker, Regine; Friederici, Angela D; Mueller, Jutta L

    2011-01-10

    Miniature language learning can serve to model real language learning as high proficiency can be reached after very little exposure. In a previous study by Mueller et al. [18] German participants acquired non-adjacent syntactic dependencies by mere exposure to correct Italian sentences, but their ERP pattern differed from the one shown by native speakers. The present study follows up on that experiment using a similar design and material and is focused on two important issues: the influence of acoustic cues in the material and the impact of the learning procedure. With respect to the latter we compared alternating learning and test phases to a continuous learning and test phase. In addition, a splicing procedure eliminated prosodic cues in order to ensure that non-adjacent dependencies were learned instead of adjacent ones. Results for the continuous phase design showed a native-like biphasic ERP pattern, an N400 followed by a left-focused positivity. In the alternating design behavioural accuracy was lower and only an N400 was found. The results suggest an advantage of continuous learning phases for adult learners, possibly due to the absence of ungrammatical items present in the test phases in the alternating learning procedure. Furthermore, the replication of the earlier study with prosodically controlled material adds evidence to the general finding that syntactic non-adjacent dependencies can be learned from mere exposure to correct examples. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  5. Improving Parent-Child Relationships through Block Play

    ERIC Educational Resources Information Center

    Lin, Yen-Chun

    2010-01-01

    Blocks are one of the most popular playthings for children. The purpose of this article is to describe the use of block play in developing parent-child relations. This paper has two major parts. First, a brief historical overview highlights the critical roles of child's block play in learning and development. Block play contributes to children's…

  6. Blocking a Redundant Cue: What Does It Say about Preschoolers' Causal Competence?

    ERIC Educational Resources Information Center

    Kloos, Heidi; Sloutsky, Vladimir M.

    2013-01-01

    The current study investigates the degree to which preschoolers can engage in causal inferences in a blocking paradigm, a paradigm in which a cue is consistently linked with a target, either alone (A-T) or paired with another cue (AB-T). Unlike previous blocking studies with preschoolers, we manipulated the causal structure of the events without…

  7. Development of improved connection details for adjacent prestressed member bridges.

    DOT National Transportation Integrated Search

    2017-06-01

    Adjacent prestressed member girder bridges are economical systems for short spans and generally come in two types: adjacent box beam bridges and adjacent voided slab bridges. Each type provides the advantages of having low clearances because of their...

  8. Specificity and effector mechanisms of autoantibodies in congenital heart block.

    PubMed

    Wahren-Herlenius, Marie; Sonesson, Sven-Erik

    2006-12-01

    Complete congenital atrio-ventricular (AV) heart block develops in 2-5% of fetuses of Ro/SSA and La/SSB autoantibody-positive pregnant women. During pregnancy, the Ro/SSA and La/SSB antibodies are transported across the placenta and affect the fetus. Emerging data suggest that this happens by a two-stage process. In the first step, maternal autoantibodies bind fetal cardiomyocytes, dysregulate calcium homestasis and induce apoptosis in affected cells. This step might clinically correspond to a first-degree heart block, and be reversible. La/SSB antibodies can bind apoptotic cardiomyocytes and thus increase Ig deposition in the heart. The tissue damage could, as a second step, lead to spread of inflammation in genetically pre-disposed fetuses, progressing to fibrosis and calcification of the AV-node and subsequent complete congenital heart block. Early intrauterine treatment of an incomplete AV-block with fluorinated steroids has been shown to prevent progression of the heart block, making it clinically important to find specific markers to identify the high-risk pregnancies.

  9. Improved connection details for adjacent prestressed bridge beams.

    DOT National Transportation Integrated Search

    2015-03-01

    Bridges with adjacent box beams and voided slabs are simply and rapidly constructed, and are well suited to : short to medium spans. The traditional connection between the adjacent members is a shear key lled with a : conventional non-shrink grout...

  10. 78 FR 6179 - Unblocking of One Specially Designated National and Blocked Person Pursuant to Executive Order 13448

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Nationals and Blocked Persons (``SDN List'') of the individual identified in this notice whose property and... SDN List the individual listed below, whose property and interests in property were blocked pursuant...

  11. Fluvial entrainment of low density peat blocks (block carbon)

    NASA Astrophysics Data System (ADS)

    Warburton, Jeff

    2014-05-01

    In many fluvial environments low density materials are transported in significant quantities and these form an important part of the stream load and /or have a distinct impact on sedimentation in these environments. However, there are significant gaps in understanding of how these materials are entrained and transported by streams and rivers. Eroding upland peatland environments in particular, frequently have fluvial systems in which large eroded peat blocks, often exceeding 1 m in length; form an important component of the stream material flux. Transport of this material is significant in determining rates of erosion but also has important impacts in terms of damage to infrastructure and carbon loss. This paper describes a field experiment designed to establish for the first time the conditions under which large peat blocks (c. > 0.1 m b axis) are initially entrained from a rough gravel bed. The field site is Trout Beck, in the North Pennines, Northern England which is an upland wandering river channel with occasional lateral and mid channel bars. Mean low flow stage is typically 0.2 m but during flood can rapidly rise, in one to two hours, to over 1.5 m. To study peat block entrainment a bespoke data acquisition system consisting of two pressure transducers, four release triggers and time lapse camera was set up. The pressure transducers provided a record of local depth and the release triggers were embedded in peat blocks to record initial motion and arranged on the rough stream bed. The time lapse camera provided verification of timing of block entrainment (during daylight hours) and also provided information on the mechanism of initial movement. Peat blocks were cut from a local source and were equidimensional, ranging in size from 0.1 to 0.7 m. The derived entrainment function is related to a critical depth of entrainment. Results demonstrate that peat blocks are entrained when the local depth approximates the height of the peat block. Blocks frequently shift

  12. Interaction of Cracks Between Two Adjacent Indents in Glass

    NASA Technical Reports Server (NTRS)

    Choi, S. R.; Salem, J. A.

    1993-01-01

    Experimental observations of the interaction behavior of cracks between two adjacent indents were made using an indentation technique in soda-lime glass. It was specifically demonstrated how one indent crack initiates and propagates in the vicinity of another indent crack. Several types of crack interactions were examined by changing the orientation and distance of one indent relative to the other. It was found that the residual stress field produced by elastic/plastic indentation has a significant influence on controlling the mode of crack interaction. The interaction of an indent crack with a free surface was also investigated for glass and ceramic specimens.

  13. Denitrification in sediments from the hyporheic zone adjacent to a small forested stream

    USGS Publications Warehouse

    Duff, J.H.; Triska, F.J.

    1990-01-01

    Denitrifying potentials increased with increasing distance from the stream channel. Dissolved oxygen was 100% of the concentration expected in equilibrium with the atmosphere in water obtained from monitoring wells immediately adjacent to the stream but was as low as 7% of the expected value in water 11.4 m inland. Both nitrate and dissolved organic carbon decreased over summer in wells at the base of the alder-forested slope. A 48-h injection of nitrate-amended stream water into hyporheic water 8.4 m inland stimulated nitrous oxide production in the presence of acetylene. Nitrous oxide was generated as nitrate and acetylene were co-transported to a well 13 m down-gradient. Acetylene-block experiments coupled with the chemistry data suggest that denitrification can modify the chemistry of water during passage through the hyporheic zone. -from Authors

  14. [Intervention among patients with right bundle branch block and left anterior hemiblock. Operatory risk (author's transl)].

    PubMed

    Coriat, P; Harari, A; Tarot, J P; Ducardonnet, A; Viars, P

    1981-01-01

    In order to assess the risk of advanced heart block during anesthesia in patients with right bundle branch block and left anterior hemiblock, 35 consecutive patients were monitored throughout the pre-, intra- and postoperative period. As conventional ECG monitoring may only detect advanced atrioventricular block, patients were monitored according to the Holter method which can easily detect even minor changes of atrioventricular conduction namely slight increased PR interval or dropped P wave. All patients were asymptomatic, in normal sinus rhythm without second degree AV block. Surgical procedures were performed under general anesthesia (n = 15) and epidural anesthesia using lidocaine (n = 20). No episode of second or third degree atrioventricular block occurred. The only modifications observed were rare and transient increase of PR, occurring during surgical procedures in 5 patients, always associated with a sinus bradycardia. They immediately regressed at the termination of the sinus bradycardia either spontaneously or following atropine injection, strongly suggesting the responsability of increased vagal tone. Thus general or epidural anesthesia did not compromise infranodal conduction in any of the observed patients. These data indicate that anesthesia can be safely used without prophylactic preoperative insertion of pacemakers in patients with asymptomatic chronic right bundle branch block and left anterior hemi-block.

  15. Precision aligned split V-block

    DOEpatents

    George, Irwin S.

    1984-01-01

    A precision aligned split V-block for holding a workpiece during a milling operation having an expandable frame for allowing various sized workpieces to be accommodated, is easily secured directly to the mill table and having key lugs in one base of the split V-block that assures constant alignment.

  16. Feasibility of motion laws for planar one degree of freedom linkage mechanisms at dead point configurations

    NASA Astrophysics Data System (ADS)

    Lores García, E.; Veciana Fontanet, J. M.; Jordi Nebot, L.

    2018-01-01

    This paper proposes an analytical solution of the Inverse Kinematics (IK) problem at dead point configurations for any planar one degree of freedom linkage mechanism, with regard to the continuity Cn of the motion law. The systems analyzed are those whose elements are linked with lower pairs and do not present redundancies. The study aims to provide the user with some rules to facilitate the design of feasible motion profiles to be reproduced by conventional electrical actuators at these configurations. During the last decades, several methods and techniques have been developed to study this specific configuration. However, these techniques are mainly focused on solving numerically the IK indeterminacy, rather than analyzing the motion laws that the mechanisms are able to perform at these particular configurations. The analysis presented in this paper has been carried out differentiating and applying l'Hôpital's rule to the system of constraint equations ϕ (q) of the mechanism. The study also considers the feasibility of the time-domain profiles to be reproduced with conventional electrical actuators (i.e. AC/DC motors, linear actuators, etc.). To show the usefulness and effectiveness of the method, the development includes the analytical application and numerical simulations for two common one degree of freedom systems: a slider-crank and a four linkage mechanisms. Finally, experimental results are presented on a four linkage mechanism test bed.

  17. Markov prior-based block-matching algorithm for superdimension reconstruction of porous media

    NASA Astrophysics Data System (ADS)

    Li, Yang; He, Xiaohai; Teng, Qizhi; Feng, Junxi; Wu, Xiaohong

    2018-04-01

    A superdimension reconstruction algorithm is used for the reconstruction of three-dimensional (3D) structures of a porous medium based on a single two-dimensional image. The algorithm borrows the concepts of "blocks," "learning," and "dictionary" from learning-based superresolution reconstruction and applies them to the 3D reconstruction of a porous medium. In the neighborhood-matching process of the conventional superdimension reconstruction algorithm, the Euclidean distance is used as a criterion, although it may not really reflect the structural correlation between adjacent blocks in an actual situation. Hence, in this study, regular items are adopted as prior knowledge in the reconstruction process, and a Markov prior-based block-matching algorithm for superdimension reconstruction is developed for more accurate reconstruction. The algorithm simultaneously takes into consideration the probabilistic relationship between the already reconstructed blocks in three different perpendicular directions (x , y , and z ) and the block to be reconstructed, and the maximum value of the probability product of the blocks to be reconstructed (as found in the dictionary for the three directions) is adopted as the basis for the final block selection. Using this approach, the problem of an imprecise spatial structure caused by a point simulation can be overcome. The problem of artifacts in the reconstructed structure is also addressed through the addition of hard data and by neighborhood matching. To verify the improved reconstruction accuracy of the proposed method, the statistical and morphological features of the results from the proposed method and traditional superdimension reconstruction method are compared with those of the target system. The proposed superdimension reconstruction algorithm is confirmed to enable a more accurate reconstruction of the target system while also eliminating artifacts.

  18. Rates and timing of vertical-axis block rotations across the Sierra Nevada-Walker Lane transition in the Bodie Hills

    NASA Astrophysics Data System (ADS)

    Rood, D. H.; Herman, S.; Burbank, D.; Bogue, S.

    2008-12-01

    We use paleomagnetic data from Tertiary volcanic rocks to address the rates and timing of vertical-axis block rotation across the Sierra Nevada-Walker Lane transition in the Bodie Hills, California/Nevada. In zones of continental deformation, block rotations are an important mechanism for permanent stain accommodation, and thus may be crucial to testing geodetic block models and resolving geologic-geodetic slip discrepancies. In our study, data included in the paleomagetic site means are high quality AF demagnetization results (least squared fits that generally include 5-7 points with MAD values less than 1). Thermal demagnetization results match the AF directions, and both thermal demag and rockmag results indicate strong ChRM, mostly carried by single domain magnetite. The site means used to calculate the VGPs all have a95 values less than 10 (mostly 2-5) and include 6-11 sites each. Each site (and thus site mean) has a reasonably well-known structural correction. The VGP scatter values range from 12 to 16 degrees, indicating that they include appropriate secular variation. The mean declinations and 95 percent confidence limits for each VGP timeslice are statistically distinct from one another (71 ± 9, 39 ± 13, and 11 ± 11 degrees). The slope of a linear regression fit to the age versus declination data gives a rate of vertical axis block rotation of approximately 3-4 degrees/Myr. Fitting two separate lines to the age vs. declination data would indicate an increase in the rates of rotation since ~10 Ma. Two possible interpretations of the data are: (1) the rotations began during or before the Middle Miocene, or (2) rates of rotation were high initially (e.g. ~10 Ma) and decelerated until the Pliocene. These data have implications for the (1) timing and spatial extent of distributed strain accumulation related to the initiation of the San Andreas Fault-Eastern California Shear Zone-Walker Lane transform plate boundary, (2) transfer of transform plate boundary

  19. High degree-of-freedom dynamic manipulation

    NASA Astrophysics Data System (ADS)

    Murphy, Michael P.; Stephens, Benjamin; Abe, Yeuhi; Rizzi, Alfred A.

    2012-06-01

    The creation of high degree of freedom dynamic mobile manipulation techniques and behaviors will allow robots to accomplish difficult tasks in the field. We are investigating the use of the body and legs of legged robots to improve the strength, velocity, and workspace of an integrated manipulator to accomplish dynamic manipulation. This is an especially challenging task, as all of the degrees of freedom are active at all times, the dynamic forces generated are high, and the legged system must maintain robust balance throughout the duration of the tasks. To accomplish this goal, we are utilizing trajectory optimization techniques to generate feasible open-loop behaviors for our 28 dof quadruped robot (BigDog) by planning the trajectories in a 13 dimensional space. Covariance Matrix Adaptation techniques are utilized to optimize for several criteria such as payload capability and task completion speed while also obeying constraints such as torque and velocity limits, kinematic limits, and center of pressure location. These open-loop behaviors are then used to generate feed-forward terms, which are subsequently used online to improve tracking and maintain low controller gains. Some initial results on one of our existing balancing quadruped robots with an additional human-arm-like manipulator are demonstrated on robot hardware, including dynamic lifting and throwing of heavy objects 16.5kg cinder blocks, using motions that resemble a human athlete more than typical robotic motions. Increased payload capacity is accomplished through coordinated body motion.

  20. Vertical and lateral fluid flow related to a large growth fault, South Eugene Island Block 330 field, offshore Louisiana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Losh, S.; Eglinton, L.; Schoell, M.

    1999-02-01

    Data from sediments in and near a large growth fault adjacent to the giant South Eugene Island Block 330 field, offshore Louisiana, indicate that the fault has acted as a conduit for fluids whose flux has varied in space and time. Core and cuttings samples from two wells that penetrated the same fault about 300 m apart show markedly different thermal histories and evidence for mass flux. Sediments within and adjacent to the fault zone in the US Department of Energy-Pennzoil Pathfinder well at about 2200 m SSTVD (subsea true vertical depth) showed little paleothermal or geochemical evidence for through-goingmore » fluid flow. The sediments were characterized by low vitrinite reflectances (R{sub {omicron}}), averaging 0.3% R{sub {omicron}}, moderate to high {delta}{sup 18}O and {delta}{sup 13}C values, and little difference in major or trace element composition between deformed and undeformed sediments. In contrast, faulted sediments from the A6ST well, which intersects the A fault at 1993 m SSTVD, show evidence for a paleothermal anomaly (0.55% R{sub {omicron}}) and depleted {delta}{sup 18}O and {delta}{sup 13}C values. Overall, indicators of mass and heat flux indicate the main growth fault zone in South Eugene Island Block 330 has acted as a conduit for ascending fluids, although the cumulative fluxes vary along strike. This conclusion is corroborated by oil and gas distribution in downthrown sands in Blocks 330 and 331, which identify the fault system in northwestern Block 330 as a major feeder.« less

  1. Binding blocks: building the Universe one nucleus at a time

    NASA Astrophysics Data System (ADS)

    Diget, C. Aa; Pastore, A.; Leech, K.; Haylett, T.; Lock, S.; Sanders, T.; Shelley, M.; Willett, H. V.; Keegans, J.; Sinclair, L.; Simpson, E. C.; Binding Blocks Collaboration

    2017-03-01

    We present a new teaching and outreach activity based around the construction of a three-dimensional chart of isotopes using \\text{LEG}{{\\text{O}}\\circledR} bricks5. The activity, binding blocks, demonstrates nuclear and astrophysical processes through a seven-meter chart of all nuclear isotopes, built from over 26 000 \\text{LEG}{{\\text{O}}\\circledR} bricks. It integrates A-Level and GCSE curricula across areas of nuclear physics, astrophysics, and chemistry, including: nuclear decays (through the colours in the chart); nuclear binding energy (through tower heights); production of chemical elements in the cosmos; fusion processes in stars and fusion energy on Earth; as well as links to medical physics, particularly diagnostics and radiotherapy.

  2. Influence of needle position on lumbar segmental nerve root block selectivity.

    PubMed

    Wolff, André P; Groen, Gerbrand J; Wilder-Smith, Oliver H

    2006-01-01

    In patients with chronic low back pain radiating to the leg, segmental nerve root blocks (SNRBs) are performed to predict surgical outcome and identify the putative symptomatic spinal nerve. Epidural spread may lead to false interpretation, affecting clinical decision making. Systematic fluoroscopic analysis of epidural local anesthetic spread and its relationship to needle tip location has not been published to date. Study aims include assessment of epidural local anesthetic spread and its relationship to needle position during fluoroscopy-assisted blocks. Patients scheduled for L4, L5, and S1 blocks were included in this prospective observational study. Under fluoroscopy and electrostimulation, they received 0.5 mL of a mixture containing lidocaine 5 mg and iohexol 75 mg. X-rays with needle tip and contrast were scored for no epidural spread (grade 0), local spread epidurally (grade 1), or to adjacent nerve roots (grade 2). Sixty-five patients were analyzed for epidural spread, 62 for needle position. Grade 1 epidural spread occurred in 47% of L4 and 28% of L5 blocks and grade 2 spread in 3 blocks (5%; L5 n = 1, S1 n = 2). For lumbar blocks, the needle was most frequently found in the lateral upper half of the intervertebral foramen. Epidural spread occurred more frequently with medial needle positions (P = .06). The findings suggest (P = .06) that the risk of grade 1 and 2 lumbar epidural spread, which results in decreased SNRB selectivity, is greater with medial needle positions in the intervertebral foramen. The variability in anatomic position of the dorsal root ganglion necessitates electrostimulation to guide SNRB in addition to fluoroscopy.

  3. Perception of the Acquisition of Generic Competences in Engineering Degrees

    ERIC Educational Resources Information Center

    Olmedo-Torre, Noelia; Martínez, María Martínez; Perez-Poch, Antoni; García, Beatriz Amante

    2018-01-01

    The aim of this paper is to analyze what generic competencies at the "Universitat Politécnica de Catalunya" (UPC BarcelonaTech) are most evaluated by the teaching staff belonging to the first curricular block of industrial engineering degree courses at the Barcelona "Escola Universitaria d'Enginyeria Técnica Industrial," and…

  4. Flow and transport within a coastal aquifer adjacent to a stratified water body

    NASA Astrophysics Data System (ADS)

    Oz, Imri; Yechieli, Yoseph; Eyal, Shalev; Gavrieli, Ittai; Gvirtzman, Haim

    2016-04-01

    also show that this configuration of three interfaces and three circulation cells, which is expected to develop adjacent to the stratified Dead Sea, is expected to decrease the dissolution rates of salt layer that is located within the adjacent aquifer, by one order of magnitude in comparison to the dissolution rates today. Therefore, the processes of salt dissolution and sinkhole formation adjacent to the Dead Sea will be relatively restrained.

  5. Tier-Adjacency Is Not a Necessary Condition for Learning Phonotactic Dependencies

    ERIC Educational Resources Information Center

    Koo, Hahn; Callahan, Lydia

    2012-01-01

    One hypothesis raised by Newport and Aslin to explain how speakers learn dependencies between nonadjacent phonemes is that speakers track bigram probabilities between two segments that are adjacent to each other within a tier of their own. The hypothesis predicts that a dependency between segments separated from each other at the tier level cannot…

  6. Which one is more effective for analgesia in infratentorial craniotomy? The scalp block or local anesthetic infiltration.

    PubMed

    Akcil, Eren Fatma; Dilmen, Ozlem Korkmaz; Vehid, Hayriye; Ibısoglu, Lutfiye Serap; Tunali, Yusuf

    2017-03-01

    The most painful stages of craniotomy are the placement of the pin head holder and the skin incision. The primary aim of the present study is to compare the effects of the scalp block and the local anesthetic infiltration with bupivacaine 0.5% on the hemodynamic response during the pin head holder application and the skin incision in infratentorial craniotomies. The secondary aims are the effects on pain scores and morphine consumption during the postoperative 24h. This prospective, randomized and placebo controlled study included forty seven patients (ASA I, II and III). The scalp block was performed in the Group S, the local anesthetic infiltration was performed in the Group I and the control group (Group C) only received remifentanil as an analgesic during the intraoperative period. The hemodynamic response to the pin head holder application and the skin incision, as well as postoperative pain intensity, cumulative morphine consumption and opioid related side effects were compared. The scalp block reduced the hemodynamic response to the pin head holder application and the skin incision in infratentorial craniotomies. The local anesthetic infiltration reduced the hemodynamic response to the skin incision. As well as both scalp block and local anesthetic infiltration reduced the cumulative morphine consumption in postoperative 24h. Moreover, the pain intensity was lower after scalp block in the early postoperative period. The scalp block may provide better analgesia in infratentorial craniotomies than local anesthetic infiltration. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. 31 CFR 510.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Blocked account; blocked property. 510.301 Section 510.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Definitions § 510.301 Blocked account; blocked property. The terms blocked account and blocked property shall...

  8. 31 CFR 510.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Blocked account; blocked property. 510.301 Section 510.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Definitions § 510.301 Blocked account; blocked property. The terms blocked account and blocked property shall...

  9. 31 CFR 510.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Blocked account; blocked property. 510.301 Section 510.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Definitions § 510.301 Blocked account; blocked property. The terms blocked account and blocked property shall...

  10. Liposomal Bupivacaine as a Single-Injection Peripheral Nerve Block: A Dose-Response Study

    PubMed Central

    Ilfeld, Brian M.; Malhotra, Nisha; Furnish, Timothy J.; Donohue, Michael C.; Madison, Sarah J.

    2013-01-01

    Background Currently available local anesthetics approved for single-injection peripheral nerve blocks have a maximum duration less than 24 hours. A liposomal bupivacaine formulation (EXPAREL®, Pacira Pharmaceuticals, Inc., San Diego, California), releasing bupivacaine over 96 hours, recently gained Food and Drug Administration approval exclusively for wound infiltration, but not peripheral nerve blocks. Methods Bilateral single-injection femoral nerve blocks were administered in healthy volunteers (n=14). For each block, liposomal bupivacaine (0–80 mg) was mixed with normal saline to produce 30 mL of study fluid. Each subject received two different doses, one on each side, applied randomly in a double-masked fashion. The end points included the maximum voluntary isometric contraction (MVIC) of the quadriceps femoris muscle and tolerance to cutaneous electrical current in the femoral nerve distribution. Measurements were performed from baseline until quadriceps MVIC returned to 80% of baseline bilaterally. Results There were statistically significant dose responses in MVIC (0.09% / mg, SE = 0.03, 95% CI 0.04 to 0.14, p = 0.002) and tolerance to cutaneous current (−0.03 mA / mg, SE = 0.01, 95% CI −0.04 to 0.02, p < 0.001), however, in the opposite direction than expected (the higher the dose, the lower the observed effect). This inverse relationship is biologically implausible, and most likely due to the limited sample size and the subjective nature of the measurement instruments. While peak effects occurred within 24 hours after block administration in 75% of cases (95% CI 43 to 93%), block duration usually lasted much longer: for bupivacaine doses above 40 mg, tolerance to cutaneous current did not return to within 20% above baseline until after 24 h in 100% of subjects (95% CI 56 to 100). MVIC did not consistently return to within 20% of baseline until after 24 hours in 90% of subjects (95% CI 54 to 100%). Motor block duration was not correlated with

  11. 49 CFR 236.827 - System, block signal.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false System, block signal. 236.827 Section 236.827..., MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.827 System, block signal. A method of governing the movement of trains into or within one or more blocks by...

  12. 49 CFR 236.827 - System, block signal.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false System, block signal. 236.827 Section 236.827..., MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.827 System, block signal. A method of governing the movement of trains into or within one or more blocks by...

  13. Hybrid Semiclassical Theory of Quantum Quenches in One-Dimensional Systems

    NASA Astrophysics Data System (ADS)

    Moca, Cǎtǎlin Paşcu; Kormos, Márton; Zaránd, Gergely

    2017-09-01

    We develop a hybrid semiclassical method to study the time evolution of one-dimensional quantum systems in and out of equilibrium. Our method handles internal degrees of freedom completely quantum mechanically by a modified time-evolving block decimation method while treating orbital quasiparticle motion classically. We can follow dynamics up to time scales well beyond the reach of standard numerical methods to observe the crossover between preequilibrated and locally phase equilibrated states. As an application, we investigate the quench dynamics and phase fluctuations of a pair of tunnel-coupled one-dimensional Bose condensates. We demonstrate the emergence of soliton-collision-induced phase propagation, soliton-entropy production, and multistep thermalization. Our method can be applied to a wide range of gapped one-dimensional systems.

  14. Chaotic Mountain Blocks in Pluto’s Sputnik Planitia

    NASA Astrophysics Data System (ADS)

    Singer, Kelsi N.; Knight, Katherine I.; Stern, S. Alan; Olkin, Catherine; Grundy, William M.; McKinnon, William B.; Moore, Jeffrey M.; Schenk, Paul M.; Spencer, John R.; Weaver, Harold A.; Young, Leslie; Ennico, Kimberly; New Horizons Geology, Geophysics and Imaging Science Theme Team, The New Horizons Surface Composition Science Theme Team

    2017-10-01

    One of the first high-resolution Pluto images returned by New Horizons displayed a collection of tall, jagged peaks rising out of the large nitrogen ice sheet informally known as Sputnik Planitia (SP). This mountain range was later revealed to be one of several along the western edge of SP. The mountains are several hundred broken-up blocks of Pluto’s primarily water ice lithosphere and some retain surface terrains similar to the nearby intact crust surrounding SP. Water ice with some fractures or porosity is likely >5% less dense than solid N2 ice at Pluto’s temperatures. Thus it is possible the blocks are, or were, floating icebergs or at least partially suspended to the point that some blocks appear to be tilted as if they have faltered (Moore et al., 2016, Science, 351, 1284-1293).We analyze four mountain ranges on the western edge of SP and compare to chaotic terrains on Europa and Mars. The blocks on Pluto have angular planforms but we characterize their size using block surface area converted to an equivalent circular diameter. Topography was used to define block extents. The blocks range in size from 3-30 km in diameter, with a mode of ~8-10 km. Blocks range from 0.2-3.8 km in height, and block height generally increases with block diameter. One or more dark layers can be identified in a few scarp faces, and are at a similar depth to each other and to layers seen in fault and crater walls elsewhere on Pluto. A large N-S trending fault system runs tangential to SP and may be the source of crustal disruption on the western side.On Europa and Mars block sizes vary greatly between different chaos regions, but Conamara Chaos has an average block size of ~5 km in diameter, smaller than that typically seen on Pluto. Also the blocks often transition into fractured terrain still connected to the surround lithosphere at the periphery of the chaos regions. The source regions for the blocks are more obvious on Europa and Mars. Additionally the block heights on

  15. Ricci time in the Lemaître-Tolman model and the block universe

    NASA Astrophysics Data System (ADS)

    Elmahalawy, Yasser; Hellaby, Charles; Ellis, George F. R.

    2015-10-01

    It is common to think of our universe according to the "block universe" concept, which says that spacetime consists of many "stacked" three-surfaces, labelled by some kind of proper time, . Standard ideas do not distinguish past and future, but Ellis' "evolving block universe" tries to make a fundamental distinction. One proposal for this proper time is the proper time measured along the timelike Ricci eigenlines, starting from the big bang. This work investigates the shape of the "Ricci time" surfaces relative to the the null surfaces. We use the Lemaître-Tolman metric as our inhomogeneous spacetime model, and we find the necessary and sufficient conditions for these constant surfaces, , to be spacelike or timelike. Furthermore, we look at the effect of strong gravity domains by determining the location of timelike S regions relative to apparent horizons. We find that constant Ricci time surfaces are always spacelike near the big bang, while at late times (near the crunch or the extreme far future), they are only timelike under special circumstances. At intermediate times, timelike S regions are common unless the variation of the bang time is restricted. The regions where these surfaces become timelike are often adjacent to apparent horizons, but always outside them, and in particular timelike S regions do not occur inside the horizons of black-hole-like models.

  16. Combined KHFAC + DC nerve block without onset or reduced nerve conductivity after block

    NASA Astrophysics Data System (ADS)

    Franke, Manfred; Vrabec, Tina; Wainright, Jesse; Bhadra, Niloy; Bhadra, Narendra; Kilgore, Kevin

    2014-10-01

    Objective. Kilohertz frequency alternating current (KHFAC) waveforms have been shown to provide peripheral nerve conductivity block in many acute and chronic animal models. KHFAC nerve block could be used to address multiple disorders caused by neural over-activity, including blocking pain and spasticity. However, one drawback of KHFAC block is a transient activation of nerve fibers during the initiation of the nerve block, called the onset response. The objective of this study is to evaluate the feasibility of using charge balanced direct current (CBDC) waveforms to temporarily block motor nerve conductivity distally to the KHFAC electrodes to mitigate the block onset-response. Approach. A total of eight animals were used in this study. A set of four animals were used to assess feasibility and reproducibility of a combined KHFAC + CBDC block. A following randomized study, conducted on a second set of four animals, compared the onset response resulting from KHFAC alone and combined KHFAC + CBDC waveforms. To quantify the onset, peak forces and the force-time integral were measured during KHFAC block initiation. Nerve conductivity was monitored throughout the study by comparing muscle twitch forces evoked by supra-maximal stimulation proximal and distal to the block electrodes. Each animal of the randomized study received at least 300 s (range: 318-1563 s) of cumulative dc to investigate the impact of combined KHFAC + CBDC on nerve viability. Main results. The peak onset force was reduced significantly from 20.73 N (range: 18.6-26.5 N) with KHFAC alone to 0.45 N (range: 0.2-0.7 N) with the combined CBDC and KHFAC block waveform (p < 0.001). The area under the force curve was reduced from 6.8 Ns (range: 3.5-21.9 Ns) to 0.54 Ns (range: 0.18-0.86 Ns) (p < 0.01). No change in nerve conductivity was observed after application of the combined KHFAC + CBDC block relative to KHFAC waveforms. Significance. The distal application of CBDC can significantly reduce or even

  17. A comparison of retrobulbar block, sub-Tenon block, and topical anesthesia during cataract surgery.

    PubMed

    Ryu, Jung-Hee; Kim, Minsuk; Bahk, Jae-Hyon; Do, Sang-Hwan; Cheong, Il-Young; Kim, Yong-Chul

    2009-01-01

    This randomized, double-blinded, prospective study was performed to compare the intraoperative hemodynamic variables and the patient-reported outcomes, such as intra- and postoperative analgesia and patient satisfaction, of retrobulbar block, sub-Tenon block, and topical anesthesia during cataract surgery under monitored anesthesia care. Eighty-one patients, ASA physical status I-III, undergoing elective cataract surgery under monitored anesthesia care, aged between 43 and 78 years, were randomly assigned to three groups: retrobulbar block (group R), sub-Tenon block (group S), or topical anesthesia (group T). Three minutes after the start of monitored anesthesia care with lidocaine-propofol-remifentanil mixture, an ophthalmologist performed regional anesthesia. Intraoperative hemodynamics, pain score, and patients' satisfaction with the anesthetic experiences were recorded by a study-blinded anesthesiologist. Mean arterial pressure and heart rate in group R were significantly higher than those in groups S and T during and just after the regional block (p<0.05). Group R required smaller dosage of patient controlled sedation and fewer supplemental bolus doses than groups S and T (p<0.05). On the other hand, group S showed the highest satisfaction scores among the three groups (p<0.05). Sub-Tenon block seems to be better than retrobulbar block and topical anesthesia in patient satisfaction though adequate analgesia was achieved after retrobulbar block during cataract surgery under monitored anesthesia care.

  18. Color Image Classification Using Block Matching and Learning

    NASA Astrophysics Data System (ADS)

    Kondo, Kazuki; Hotta, Seiji

    In this paper, we propose block matching and learning for color image classification. In our method, training images are partitioned into small blocks. Given a test image, it is also partitioned into small blocks, and mean-blocks corresponding to each test block are calculated with neighbor training blocks. Our method classifies a test image into the class that has the shortest total sum of distances between mean blocks and test ones. We also propose a learning method for reducing memory requirement. Experimental results show that our classification outperforms other classifiers such as support vector machine with bag of keypoints.

  19. Block Play: Practical Suggestions for Common Dilemmas

    ERIC Educational Resources Information Center

    Tunks, Karyn Wellhousen

    2009-01-01

    Learning materials and teaching methods used in early childhood classrooms have fluctuated greatly over the past century. However, one learning tool has stood the test of time: Wood building blocks, often called unit blocks, continue to be a source of pleasure and learning for young children at play. Wood blocks have the unique capacity to engage…

  20. The tiger beetles (Coleoptera, Carabidae, Cicindelinae) of Israel and adjacent lands

    PubMed Central

    Matalin, Andrey V.; Chikatunov, Vladimir I.

    2016-01-01

    Abstract Based on field studies, museums collections and literature sources, the current knowledge of the tiger beetle fauna of Israel and adjacent lands is presented. In Israel eight species occur, one of them with two subspecies, while in the Sinai Peninsula nine species of tiger beetles are now known. In the combined regions seven genera from two tribes were found. The Rift Valley with six cicindelids species is the most specious region of Israel. Cylindera contorta valdenbergi and Cicindela javeti azari have localized distributions and should be considered regional endemics. A similarity analysis of the tiger beetles faunas of different regions of Israel and the Sinai Peninsula reveal two clusters of species. The first includes the Great Rift Valley and most parts of the Sinai Peninsula, and the second incorporates most regions of Israel together with Central Sinai Foothills. Five distinct adult phenological groups of tiger beetles can be distinguished in these two clusters: active all-year (three species), spring-fall (five species), summer (two species), spring-summer (one species) and spring (one species). The likely origins of the tiger beetle fauna of this area are presented. An annotated list and illustrated identification key of the Cicindelinae of Israel and adjacent lands are provided. PMID:27110198

  1. Magnetophysiologic and echocardiographic comparison of blocked atrial bigeminy and 2:1 atrioventricular block in the fetus.

    PubMed

    Wiggins, Delonia L; Strasburger, Janette F; Gotteiner, Nina L; Cuneo, Bettina; Wakai, Ronald T

    2013-08-01

    Blocked atrial bigeminy (BAB) and second-degree atrioventricular block with 2:1 conduction block (2:1 AVB) both present as ventricular bradycardia and can be difficult to distinguish by echocardiography. Since the prognosis and clinical management of these rhythms are different, an accurate diagnosis is essential. To identify magnetic and mechanical heart rate and rhythm parameters that could reliably distinguish BAB from 2:1 AVB. A retrospective study of ten BAB and seven 2:1 AVB subjects was performed, using fMCG and pulsed Doppler ultrasound. Distinguishing BAB from 2:1 AVB by using fMCG was relatively straightforward because in BAB the ectopic P wave (P') occurred early, resulting in a bigeminal (short-long) atrial rhythm. The normalized coupling interval of the ectopic beat (PP' of the blocked beat to PP of the conducted beat) was 0.29 ± 0.03. In contrast, the echocardiographic assessment of inflow-outflow gave a normalized mechanical coupling interval (AA'/AA) near 0.5, which made it difficult to distinguish BAB from 2:1 AVB. Heart rate distinguished most subjects with BAB from those with 2:1 AVB (82 ± 5.7 beats/min vs 69 ± 4.2 beats/min), but was not a completely reliable indicator. In most subjects, BAB alternated with sinus rhythm or other rhythms, resulting in complex heart rate and rhythm patterns. Fetal BAB and 2:1 AV block can be difficult to distinguish using echocardiography because in many fetuses with BAB the mechanical rhythm does not accurately reflect the magnetic rhythm. fMCG provides a more reliable means of making a differential diagnosis. Copyright © 2013 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  2. A systematic review of definitions and classification systems of adjacent segment pathology.

    PubMed

    Kraemer, Paul; Fehlings, Michael G; Hashimoto, Robin; Lee, Michael J; Anderson, Paul A; Chapman, Jens R; Raich, Annie; Norvell, Daniel C

    2012-10-15

    Systematic review. To undertake a systematic review to determine how "adjacent segment degeneration," "adjacent segment disease," or clinical pathological processes that serve as surrogates for adjacent segment pathology are classified and defined in the peer-reviewed literature. Adjacent segment degeneration and adjacent segment disease are terms referring to degenerative changes known to occur after reconstructive spine surgery, most commonly at an immediately adjacent functional spinal unit. These can include disc degeneration, instability, spinal stenosis, facet degeneration, and deformity. The true incidence and clinical impact of degenerative changes at the adjacent segment is unclear because there is lack of a universally accepted classification system that rigorously addresses clinical and radiological issues. A systematic review of the English language literature was undertaken and articles were classified using the Grades of Recommendation Assessment, Development, and Evaluation criteria. RESULTS.: Seven classification systems of spinal degeneration, including degeneration at the adjacent segment, were identified. None have been evaluated for reliability or validity specific to patients with degeneration at the adjacent segment. The ways in which terms related to adjacent segment "degeneration" or "disease" are defined in the peer-reviewed literature are highly variable. On the basis of the systematic review presented in this article, no formal classification system for either cervical or thoracolumbar adjacent segment disorders currently exists. No recommendations regarding the use of current classification of degeneration at any segments can be made based on the available literature. A new comprehensive definition for adjacent segment pathology (ASP, the now preferred terminology) has been proposed in this Focus Issue, which reflects the diverse pathology observed at functional spinal units adjacent to previous spinal reconstruction and balances

  3. One-Course-at-a-Time "Block Plan" Re-examined by College That Adopted It 25 Years Ago.

    ERIC Educational Resources Information Center

    Gose, Ben

    1995-01-01

    Colorado College is reconsidering its block scheduling, in which students take eight immersion courses consecutively within the academic year, rather than taking several courses concurrently. Advantages of block scheduling include more intensive instruction and increased student focus on subject matter. Some students and faculty are concerned that…

  4. Supercontinent Formation in 3-D Spherical Mantle Convection Models With Multiple Continental Blocks

    NASA Astrophysics Data System (ADS)

    Zhang, N.; Zhong, S.; McNamara, A.

    2007-12-01

    Much of the large-scale tectonics on the Earth in the last Ga is predominated by the assembly and breakup of supercontinents Rodinia and Pangea. However, the mechanism that is responsible for supercontinent formation remains poorly understood. Zhong et al [2007] recently showed that mantle convection with moderately strong lithosphere and lower mantle is characterized by a largely degree-1 planform in which one hemisphere is predominated by upwellings while the other by downwellings. They further suggested that the downwellings should attract all the continental blocks to merge in the downwelling hemisphere, thus leading to supercontinent formation there. However, Zhong et al. [2007] did not consider drifting and collision processes of continents. In this study, we explore the supercontinent formation mechanisms by including drifting and collision processes of multiple continental blocks in 3-D spherical mantle convection models. We use thermochemical CitcomS code to model 3-D spherical mantle convection with continental blocks. In our models, particles are used to represent continents and to track their motions. We found that for models with mantle viscosity (i.e., moderately strong lithosphere and lower mantle) that leads to degree-1 convection as reported in Zhong et al. [2007], initially evenly- distributed continental blocks always merge to form a supercontinent on a time-scale of about 6 transit times (i.e., corresponding to about 300 Ma). The hemisphere where a supercontinent is formed is predominated by downwellings as continents merge towards there, while the other hemisphere by upwellings. However, after the supercontinent formation, upwellings are generated beneath the supercontinent. This scenario is qualitatively consistent with what Zhong et al. [2007] proposed. We also found that while some convection models with intrinsically small-scale planforms may also lead to formation of a supercontinent, some other models may fail to produce a supercontinent

  5. Delayed Acquisition of Non-Adjacent Vocalic Distributional Regularities

    ERIC Educational Resources Information Center

    Gonzalez-Gomez, Nayeli; Nazzi, Thierry

    2016-01-01

    The ability to compute non-adjacent regularities is key in the acquisition of a new language. In the domain of phonology/phonotactics, sensitivity to non-adjacent regularities between consonants has been found to appear between 7 and 10 months. The present study focuses on the emergence of a posterior-anterior (PA) bias, a regularity involving two…

  6. Electrically and chemically tunable soft-solid block copolymer structural color (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Park, Cheolmin

    2016-09-01

    1D photonic crystals based on the periodic stacking of two different dielectric layers have been widely studied due to their potential use in low-power reflective mode displays, e-books and sensors, but the fabrication of mechanically flexible polymer structural color (SC) films, with electro-active color switching, remains challenging. Here, we demonstrate free-standing electric field tunable ionic liquid swollen block copolymer films. Placement of a polymer/ionic liquid (IL) film-reservoir adjacent to a self-assembled poly(styrene-block-quaternized 2vinyl pyridine) (PS-b-QP2VP) copolymer SC film allowed the development of R, G and B full-color SC block copolymer films by swelling of the QP2VP domains by the ionic liquid associated with water molecules. The IL-polymer/BCP SC film is mechanically flexible with excellent color stability over several days at ambient conditions. The selective swelling of the QP2VP domains could be controlled by both the ratio of the IL to a polymer in the gel-like IL reservoir layer and by an applied voltage in the range of -3V to +6V using a metal/IL reservoir/SC film/IL reservoir/metal capacitor type device.

  7. 77 FR 10808 - Designation of One Entity Pursuant to Executive Order 13572 of April 29, 2011, “Blocking Property...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... Executive Order 13572 of April 29, 2011, ``Blocking Property of Certain Persons With Respect to Human Rights..., 2011, ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in Syria.'' DATES: The..., ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in Syria,'' (the ``Order...

  8. 76 FR 54534 - Designation of One Entity Pursuant to Executive Order 13572 of April 29, 2011, “Blocking Property...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... Executive Order 13572 of April 29, 2011, ``Blocking Property of Certain Persons with Respect to Human Rights... April 29, 2011, ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in Syria..., ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in Syria,'' (the ``Order...

  9. Binaural unmasking with multiple adjacent masking electrodes in bilateral cochlear implant users

    PubMed Central

    Lu, Thomas; Litovsky, Ruth; Zeng, Fan-Gang

    2011-01-01

    Bilateral cochlear implant (BiCI) users gain an advantage in noisy situations from a second implant, but their bilateral performance falls short of normal hearing listeners. Channel interactions due to overlapping electrical fields between electrodes can impair speech perception, but its role in limiting binaural hearing performance has not been well characterized. To address the issue, binaural masking level differences (BMLD) for a 125 Hz tone in narrowband noise were measured using a pair of pitch-matched electrodes while simultaneously presenting the same masking noise to adjacent electrodes, representing a more realistic stimulation condition compared to prior studies that used only a single electrode pair. For five subjects, BMLDs averaged 8.9 ± 1.0 dB (mean ± s.e.) in single electrode pairs but dropped to 2.1 ± 0.4 dB when presenting noise on adjacent masking electrodes, demonstrating a negative impact of the additional maskers. Removing the masking noise from only the pitch-matched electrode pair not only lowered thresholds but also resulted in smaller BMLDs. The degree of channel interaction estimated from auditory nerve evoked potentials in three subjects was significantly and negatively correlated with BMLD. The data suggest that if the amount of channel interactions can be reduced, BiCI users may experience some performance improvements related to binaural hearing. PMID:21682415

  10. 31 CFR 598.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Blocked account; blocked property. 598.301 Section 598.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS General Definitions § 598.301 Blocked account; blocked property. The terms blocked account and...

  11. 31 CFR 598.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Blocked account; blocked property. 598.301 Section 598.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS General Definitions § 598.301 Blocked account; blocked property. The terms blocked account and...

  12. 31 CFR 598.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Blocked account; blocked property. 598.301 Section 598.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS General Definitions § 598.301 Blocked account; blocked property. The terms blocked account and...

  13. 31 CFR 598.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Blocked account; blocked property. 598.301 Section 598.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS General Definitions § 598.301 Blocked account; blocked property. The terms blocked account and...

  14. Mode-based equivalent multi-degree-of-freedom system for one-dimensional viscoelastic response analysis of layered soil deposit

    NASA Astrophysics Data System (ADS)

    Li, Chong; Yuan, Juyun; Yu, Haitao; Yuan, Yong

    2018-01-01

    Discrete models such as the lumped parameter model and the finite element model are widely used in the solution of soil amplification of earthquakes. However, neither of the models will accurately estimate the natural frequencies of soil deposit, nor simulate a damping of frequency independence. This research develops a new discrete model for one-dimensional viscoelastic response analysis of layered soil deposit based on the mode equivalence method. The new discrete model is a one-dimensional equivalent multi-degree-of-freedom (MDOF) system characterized by a series of concentrated masses, springs and dashpots with a special configuration. The dynamic response of the equivalent MDOF system is analytically derived and the physical parameters are formulated in terms of modal properties. The equivalent MDOF system is verified through a comparison of amplification functions with the available theoretical solutions. The appropriate number of degrees of freedom (DOFs) in the equivalent MDOF system is estimated. A comparative study of the equivalent MDOF system with the existing discrete models is performed. It is shown that the proposed equivalent MDOF system can exactly present the natural frequencies and the hysteretic damping of soil deposits and provide more accurate results with fewer DOFs.

  15. The influence of cold on the recovery of three neuromuscular blocking agents in man.

    PubMed

    England, A J; Wu, X; Richards, K M; Redai, I; Feldman, S A

    1996-03-01

    The Arrhenius hypothesis suggests that change in temperature has a less marked effect on the rate of physical processes than on biological reactions. We have investigated the process underlying recovery from neuromuscular block in man by studying the effect of cooling on the rate of recovery from depolarising and non-depolarising block. Vecuronium, rocuronium and decamethonium (C10) neuromuscular block were investigated using the isolated forearm technique on awake human volunteers. In these experiments, one arm was cooled whilst the other was used as control. Moderate hypothermia decreased the rate of recovery from all three agents, but this was significantly less marked with the depolarising drug. The mean Q10 (the anticipated change in rate of a reaction across of 10 degrees C temperature gradient) of the rate of recovery for vecuronium was 3.21, rocuronium 2.86 and decamethonium 1.29. This suggests a different process in the recovery of these two types of drug. According to the Arrhenius hypothesis this would suggest that the recovery from non-depolarising drugs is likely to involve a biochemical mechanism and that recovery from decamethonium is controlled by a physical process.

  16. Tracing sources of organic matter in adjacent urban streams having different degrees of channel modification.

    PubMed

    Duan, Shuiwang; Amon, Rainer M W; Brinkmeyer, Robin L

    2014-07-01

    Urbanization and stream-channel modifications affect organic matter concentrations and quality in streams, by altering allochthonous organic matter input and in-stream transformation. This study uses multiple tracers (δ(13)C, δ(15)N, C/N ratio, and chlorophyll-a) to track sources of organic matter in two highly urbanized bayous in Houston (Texas, USA). Wastewater treatment plants (WWTPs) are located in headwaters of both bayous and contribute more than 75% to water flow. Low isotopic relatedness to natural end-members and enriched δ(15)N values suggest the influence of WWTPs on the composition of all organic matter fractions. The two bayous differ in degree of channel improvement resulting in different responses to hydrological conditions. During high flow conditions, the influence of terrestrial organic matter and sediment resuspension was much more pronounced in the Buffalo Bayou than in the concrete-lined White Oak Bayou. Particulate organic matter (POM) in White Oak Bayou had similar values of enriched δ(15)N in all subsegments, whereas in Buffalo Bayou, the degree of δ(15)N enrichment was less in the subsegments of the lower watershed. The difference in riparian zone contributions and interactions with sediments/soils was likely responsible for the compositional differences between the two bayous. Phytoplankton inputs were significantly higher in the bayous, especially in slow-flowing sections, relative to the reference sites, and elevated phytoplankton inputs accounted for the observed stable C isotope differences between FPOM and high molecular weight dissolved organic matter (HMW DOM). Relative to POM, HMW DOM in the bayous was similar to WWTP effluents and showed minor longitudinal variability in both streams suggesting that WWTPs contribute much of the DOM in the systems. Urbanization has a major influence on organic matter sources and quality in these urban water bodies and these changes seem further enhanced by stream channel modifications

  17. Organic photovoltaic cell incorporating electron conducting exciton blocking layers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forrest, Stephen R.; Lassiter, Brian E.

    2014-08-26

    The present disclosure relates to photosensitive optoelectronic devices including a compound blocking layer located between an acceptor material and a cathode, the compound blocking layer including: at least one electron conducting material, and at least one wide-gap electron conducting exciton blocking layer. For example, 3,4,9,10 perylenetetracarboxylic bisbenzimidazole (PTCBI) and 1,4,5,8-napthalene-tetracarboxylic-dianhydride (NTCDA) function as electron conducting and exciton blocking layers when interposed between the acceptor layer and cathode. Both materials serve as efficient electron conductors, leading to a fill factor as high as 0.70. By using an NTCDA/PTCBI compound blocking layer structure increased power conversion efficiency is achieved, compared to anmore » analogous device using a conventional blocking layers shown to conduct electrons via damage-induced midgap states.« less

  18. Piedramuelle Limestone in the building heritage of Oviedo, Spain, and adjacent towns.

    NASA Astrophysics Data System (ADS)

    Cardenes Van den Eynde, Victor; Mateos, Felix Javier; Valdeon, Luis; Rojo, Araceli

    2017-04-01

    The Piedramuelle limestone has a very important representation in the building heritage of Oviedo, historical capital of Asturias (Spain) and surrounding towns. This argillaceous limestone has been quarried since the High Middle Ages until the beginning of the XX century. The main mineralogical components are carbonates (mainly calcite and sometimes ankerite, 70-90%), quartz (5-15%), terrigenous minerals (6-15%) and iron oxides (<5%). Two different facies, with different constructive uses, can be clearly distinguished depending on the grain size: fine-grained facies and coarse-grained facies. The fine-grained facies has color ranging from red to yellow, slightly higher content in carbonates, higher terrigenous components and a micro crystalline texture. The coarse-grained facies is mainly yellow, with detrital clastic texture. The open porosity is higher for the coarse-grained facies (16-20%), while for the fine-grained facies it ranges between 5 and 15%. The fine-grained facies is more vulnerable to weathering than the coarse-grained one, and it is used in the building heritage mainly for ornamental details, while the coarse-grained one is found in the bigger blocks and ashlars of the buildings. Some of the buildings constructed with Piedramuelle limestone are the Cathedral, the Old University and the Palaces from the XVII and XVIII centuries. The ambiance and historical architecture of Oviedo and adjacent towns is closely linked with the textures and colors of this stone. Nowadays, the Piedramuelle limestone is not exploited anymore, being the quarries exhausted. This represents an issue from a conservation point of view, since there is not a suitable stone for replacement. In order to preserve and maintain the building heritage of these towns, it is very important to prospect and protect the remaining outcrops still able to supply this characteristic stone.

  19. Altered disc pressure profile after an osteoporotic vertebral fracture is a risk factor for adjacent vertebral body fracture

    PubMed Central

    Tzermiadianos, Michael N.; Renner, Susan M.; Phillips, Frank M.; Hadjipavlou, Alexander G.; Zindrick, Michael R.; Havey, Robert M.; Voronov, Michael

    2008-01-01

    This study investigated the effect of endplate deformity after an osteoporotic vertebral fracture in increasing the risk for adjacent vertebral fractures. Eight human lower thoracic or thoracolumbar specimens, each consisting of five vertebrae were used. To selectively fracture one of the endplates of the middle VB of each specimen a void was created under the target endplate and the specimen was flexed and compressed until failure. The fractured vertebra was subjected to spinal extension under 150 N preload that restored the anterior wall height and vertebral kyphosis, while the fractured endplate remained significantly depressed. The VB was filled with cement to stabilize the fracture, after complete evacuation of its trabecular content to ensure similar cement distribution under both the endplates. Specimens were tested in flexion-extension under 400 N preload while pressure in the discs and strain at the anterior wall of the adjacent vertebrae were recorded. Disc pressure in the intact specimens increased during flexion by 26 ± 14%. After cementation, disc pressure increased during flexion by 15 ± 11% in the discs with un-fractured endplates, while decreased by 19 ± 26.7% in the discs with the fractured endplates. During flexion, the compressive strain at the anterior wall of the vertebra next to the fractured endplate increased by 94 ± 23% compared to intact status (p < 0.05), while it did not significantly change at the vertebra next to the un-fractured endplate (18.2 ± 7.1%, p > 0.05). Subsequent flexion with compression to failure resulted in adjacent fracture close to the fractured endplate in six specimens and in a non-adjacent fracture in one specimen, while one specimen had no adjacent fractures. Depression of the fractured endplate alters the pressure profile of the damaged disc resulting in increased compressive loading of the anterior wall of adjacent vertebra that predisposes it to wedge fracture. This data suggests that

  20. Relevance of adjacent joint imaging in the evaluation of ankle fractures.

    PubMed

    Antoci, Valentin; Patel, Shaun P; Weaver, Michael J; Kwon, John Y

    2016-10-01

    Routinely obtaining adjacent joint radiographs when evaluating patients with ankle fractures may be of limited clinical utility and an unnecessary burden, particularly in the absence of clinical suspicion for concomitant injuries. One thousand, three hundred and seventy patients who sustained ankle fractures over a 5-year period presenting to two level 1 trauma centers were identified. Medical records were retrospectively reviewed for demographics, physical examination findings, and radiographic information. Analyses included descriptive statistics along with sensitivity and predictive value calculations for the presence of adjacent joint fracture. Adjacent joint imaging (n=1045 radiographs) of either the knee or foot was obtained in 873 patients (63.7%). Of those, 75/761 patients (9.9%) demonstrated additional fractures proximal to the ankle joint, most commonly of the proximal fibula. Twenty-two of 284 (7.7%) demonstrated additional fractures distal to the ankle joint, most commonly of the metatarsals. Tenderness to palpation demonstrated sensitivities of 0.92 and 0.77 and positive predictive values of 0.94 and 0.89 for the presence of proximal and distal fractures, respectively. Additionally, 19/22 (86.4%) of patients sustaining foot fractures had their injury detectable on initial ankle X-rays. Overall, only 5.5% (75/1370) of patients sustained fractures proximal to the ankle and only 0.2% (3/1370) of patients had additional foot fractures not evident on initial ankle X-rays. The addition of adjacent joint imaging for the evaluation of patients sustaining ankle fractures is low yield. As such, patient history, physical examination, and clinical suspicion should direct the need for additional X-rays. Level IV. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Aseismic blocks and destructive earthquakes in the Aegean

    NASA Astrophysics Data System (ADS)

    Stiros, Stathis

    2017-04-01

    Aseismic areas are not identified only in vast, geologically stable regions, but also within regions of active, intense, distributed deformation such as the Aegean. In the latter, "aseismic blocks" about 200m wide were recognized in the 1990's on the basis of the absence of instrumentally-derived earthquake foci, in contrast to surrounding areas. This pattern was supported by the available historical seismicity data, as well as by geologic evidence. Interestingly, GPS evidence indicates that such blocks are among the areas characterized by small deformation rates relatively to surrounding areas of higher deformation. Still, the largest and most destructive earthquake of the 1990's, the 1995 M6.6 earthquake occurred at the center of one of these "aseismic" zones at the northern part of Greece, found unprotected against seismic hazard. This case was indeed a repeat of the case of the tsunami-associated 1956 Amorgos Island M7.4 earthquake, the largest 20th century event in the Aegean back-arc region: the 1956 earthquake occurred at the center of a geologically distinct region (Cyclades Massif in Central Aegean), till then assumed aseismic. Interestingly, after 1956, the overall idea of aseismic regions remained valid, though a "promontory" of earthquake prone-areas intruding into the aseismic central Aegean was assumed. Exploitation of the archaeological excavation evidence and careful, combined analysis of historical and archaeological data and other palaeoseismic, mostly coastal data, indicated that destructive and major earthquakes have left their traces in previously assumed aseismic blocks. In the latter earthquakes typically occur with relatively low recurrence intervals, >200-300 years, much smaller than in adjacent active areas. Interestingly, areas assumed a-seismic in antiquity are among the most active in the last centuries, while areas hit by major earthquakes in the past are usually classified as areas of low seismic risk in official maps. Some reasons

  2. Impact of trap architecture, adjacent habitats, abiotic factors, and host plant phenology on captures of plum curculio (Coleoptera: Curculionidae) adults.

    PubMed

    Lafleur, Gérald; Chouinard, Gérald; Vincent, Charles; Cormier, Daniel

    2007-06-01

    Pyramid traps, 2.44 m and 3.66 m in height, were compared with standard-sized pyramid traps, 1.22 m in height, to assess the impact of trap architecture on captures of adult plum curculio, Conotrachelus nenuphar (Herbst) (Coleoptera: Curculionidae), in two apple (Malus spp.) orchards and a blueberry (Vaccinium spp.) planting. The effects of adjacent habitat (organic orchard versus wooded areas), abiotic factors, and phenological stages of apple also were assessed to determine whether these variables influenced trap captures. Standard-sized pyramidal traps captured significantly more adults than larger trap variants. In the apple orchards, most adults (70-80%) were captured before petal fall with the exception of blocks adjacent to the organic orchard (25%). Significantly more adults were captured along the edge of an apple orchard (managed using an integrated pest management strategy) facing an organic apple orchard (76%) than along the edge facing wooded areas (24%). There was a significant positive correlation between daily trap captures and mean daily temperatures before petal fall in apple orchards.

  3. Response of rotation-translation blocked proteins using Langevin dynamics on a locally harmonic landscape.

    PubMed

    Manson, Anthony C; Coalson, Rob D

    2012-10-11

    Langevin dynamics is used to compute the time evolution of the nonequilibrium motion of the atomic coordinates of a protein in response to ligand dissociation. The protein potential energy surface (PES) is approximated by a harmonic basin about the minimum of the unliganded state. Upon ligand dissociation, the protein undergoes relaxation from the bound to the unbound state. A coarse graining scheme based on rotation translation blocks (RTB) is applied to the relaxation of the two domain iron transport protein, ferric binding protein. This scheme provides a natural and efficient way to freeze out the small amplitude, high frequency motions within each rigid fragment, thereby allowing for the number of dynamical degrees of freedom to be reduced. The results obtained from all flexible atom (constraint free) dynamics are compared to those obtained using RTB-Langevin dynamics. To assess the impact of the assumed rigid fragment clustering on the temporal relaxation dynamics of the protein molecule, three distinct rigid block decompositions were generated and their responses compared. Each of the decompositions was a variant of the one-block-per-residue grouping, with their force and friction matrices being derived from their fully flexible counterpart. Monitoring the time evolution of the distance separating a selected pair of amino acids, the response curves of the blocked decompositions were similar in shape to each other and to the control system in which all atomic degrees of freedom are fully independent. The similar shape of the blocked responses showed that the variations in grouping had only a minor impact on the kinematics. Compared with the all atom responses, however, the blocked responses were faster as a result of the instantaneous transmission of force throughout each rigid block. This occurred because rigid blocking does not permit any intrablock deformation that could store or divert energy. It was found, however, that this accelerated response could be

  4. Effect of multilevel lumbar disc arthroplasty on the operative- and adjacent-level kinematics and intradiscal pressures: an in vitro human cadaveric assessment.

    PubMed

    Dmitriev, Anton E; Gill, Norman W; Kuklo, Timothy R; Rosner, Michael K

    2008-01-01

    With lumbar arthroplasty gaining popularity, limited data are available highlighting changes in adjacent-level mechanics after multilevel procedures. Compare operative- and adjacent-segment range of motion (ROM) and intradiscal pressures (IDPs) after two-level arthroplasty versus circumferential arthrodesis. Cadaveric biomechanical study. Ten human cadaveric lumbar spines were used in this investigation. Biomechanical testing was performed according to a hybrid testing protocol using an unconstrained spine simulator under axial rotation (AR), flexion extension (FE), and lateral-bending (LB) loading. Specimens were tested in the following order: 1) Intact, 2) L3-L5 total disc replacement (TDR), 3) L3-L5 anterior interbody cages+pedicle screws. IDP was recorded at proximal and distal adjacent levels and normalized to controls (%intact). Full ROM was monitored at the operative and adjacent levels and reported in degrees. Kinematics assessment revealed L3-L5 ROM reduction after both reconstructions versus intact controls (p < .05). However, global quality of segmental motion distributed over L2-S1 was preserved in the arthroplasty group but was significantly altered after circumferential fixation. Furthermore, adjacent-level ROM was increased for the arthrodesis group under LB at both segments and during AR at L2-L3 relative to controls (p < .05). FE did not reveal any intergroup statistical differences. Nonetheless, after arthrodesis IDPs were increased proximally under all three loading modalities, whereas distally a significant IDP rise was noted during AR and LB (p < .05). No statistical differences in either biomechanical parameter were recorded at the adjacent levels between intact control and TDR groups. Our results indicate no significant adjacent-level biomechanical changes between arthroplasty and control groups. In contrast, significant alterations in ROM and IDP were recorded both proximally (ROM=LB & AR; IDP=AR, FE, LB) and distally (ROM=LB; IDP=AR & LB

  5. Combined KHFAC+DC nerve block without onset or reduced nerve conductivity after block

    PubMed Central

    Franke, Manfred; Vrabec, Tina; Wainright, Jesse; Bhadra, Niloy; Bhadra, Narendra; Kilgore, Kevin

    2017-01-01

    Background Kilohertz Frequency Alternating Current waveforms (KHFAC) have been shown to provide peripheral nerve conductivity block in many acute and chronic animal models. KHFAC nerve block could be used to address multiple disorders caused by neural over-activity, including blocking pain and spasticity. However, one drawback of KHFAC block is a transient activation of nerve fibers during the initiation of the nerve block, called the onset response. The objective of this study is to evaluate the feasibility of using charge balanced direct current (CBDC) waveforms to temporarily block motor nerve conductivity distally to the KHFAC electrodes to mitigate the block onset-response. Methods A total of eight animals were used in this study. A set of four animals were used to assess feasibility and reproducibility of a combined KHFAC+CBDC block. A following randomized study, conducted on a second set of four animals, compared the onset response resulting from KHFAC alone and combined KHFAC+CBDC waveforms. To quantify the onset, peak forces and the force-time integral were measured during KHFAC block initiation. Nerve conductivity was monitored throughout the study by comparing muscle twitch forces evoked by supra-maximal stimulation proximal and distal to the block electrodes. Each animal of the randomized study received at least 300 seconds (range: 318 to 1563s) of cumulative DC to investigate the impact of combined KHFAC+CBDC on nerve viability. Results The peak onset force was reduced significantly from 20.73 N (range: 18.6–26.5 N) with KHFAC alone to 0.45 N (range: 0.2–0.7 N) with the combined CBDC and KHFAC block waveform (p<0.001). The area under the force curve was reduced from 6.8 Ns (range: 3.5–21.9 Ns) to 0.54 Ns (range: 0.18–0.86Ns) (p<0.01). No change in nerve conductivity was observed after application of the combined KHFAC+CBDC block relative to KHFAC waveforms. Conclusion The distal application of CBDC can significantly reduce or even completely

  6. Objectifying the adjacent and opposite angles: a cultural historical analysis

    NASA Astrophysics Data System (ADS)

    Daher, Wajeeh; Musallam, Nadera

    2018-02-01

    The angle topic is central to the development of geometric knowledge. Two of the basic concepts associated with this topic are the adjacent and opposite angles. It is the goal of the present study to analyze, based on the cultural historical semiotics framework, how high-achieving seventh grade students objectify the adjacent and opposite angles' concepts. We videoed the learning of a group of three high-achieving students who used technology, specifically GeoGebra, to explore geometric relations related to the adjacent and opposite angles' concepts. To analyze students' objectification of these concepts, we used the categories of objectification of knowledge (attention and awareness) and the categories of generalization (factual, contextual and symbolic), developed by Radford. The research results indicate that teacher's and students' verbal and visual signs, together with the software dynamic tools, mediated the students' objectification of the adjacent and opposite angles' concepts. Specifically, eye and gestures perceiving were part of the semiosis cycles in which the participating students were engaged and which related to the mathematical signs that signified the adjacent and the opposite angles. Moreover, the teacher's suggestions/requests/questions included/suggested semiotic signs/tools, including verbal signs that helped the students pay attention, be aware of and objectify the adjacent and opposite angles' concepts.

  7. Testing block subdivision algorithms on block designs

    NASA Astrophysics Data System (ADS)

    Wiseman, Natalie; Patterson, Zachary

    2016-01-01

    Integrated land use-transportation models predict future transportation demand taking into account how households and firms arrange themselves partly as a function of the transportation system. Recent integrated models require parcels as inputs and produce household and employment predictions at the parcel scale. Block subdivision algorithms automatically generate parcel patterns within blocks. Evaluating block subdivision algorithms is done by way of generating parcels and comparing them to those in a parcel database. Three block subdivision algorithms are evaluated on how closely they reproduce parcels of different block types found in a parcel database from Montreal, Canada. While the authors who developed each of the algorithms have evaluated them, they have used their own metrics and block types to evaluate their own algorithms. This makes it difficult to compare their strengths and weaknesses. The contribution of this paper is in resolving this difficulty with the aim of finding a better algorithm suited to subdividing each block type. The proposed hypothesis is that given the different approaches that block subdivision algorithms take, it's likely that different algorithms are better adapted to subdividing different block types. To test this, a standardized block type classification is used that consists of mutually exclusive and comprehensive categories. A statistical method is used for finding a better algorithm and the probability it will perform well for a given block type. Results suggest the oriented bounding box algorithm performs better for warped non-uniform sites, as well as gridiron and fragmented uniform sites. It also produces more similar parcel areas and widths. The Generalized Parcel Divider 1 algorithm performs better for gridiron non-uniform sites. The Straight Skeleton algorithm performs better for loop and lollipop networks as well as fragmented non-uniform and warped uniform sites. It also produces more similar parcel shapes and patterns.

  8. Perpendicularly Aligned, Anion Conducting Nanochannels in Block Copolymer Electrolyte Films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arges, Christopher G.; Kambe, Yu; Suh, Hyo Seon

    Connecting structure and morphology to bulk transport properties, such as ionic conductivity, in nanostructured polymer electrolyte materials is a difficult proposition because of the challenge to precisely and accurately control order and the orientation of the ionic domains in such polymeric films. In this work, poly(styrene-block-2-vinylpyridine) (PSbP2VP) block copolymers were assembled perpendicularly to a substrate surface over large areas through chemical surface modification at the substrate and utilizing a versatile solvent vapor annealing (SVA) technique. After block copolymer assembly, a novel chemical vapor infiltration reaction (CVIR) technique selectively converted the 2-vinylpyridine block to 2-vinyl n-methylpyridinium (NMP+ X-) groups, which aremore » anion charge carriers. The prepared block copolymer electrolytes maintained their orientation and ordered nanostructure upon the selective introduction of ion moieties into the P2VP block and post ion-exchange to other counterion forms (X- = chloride, hydroxide, etc.). The prepared block copolymer electrolyte films demonstrated high chloride ion conductivities, 45 mS cm(-1) at 20 degrees C in deionized water, the highest chloride ion conductivity for anion conducting polymer electrolyte films. Additionally, straight-line lamellae of block copolymer electrolytes were realized using chemoepitaxy and density multiplication. The devised scheme allowed for precise and accurate control of orientation of ionic domains in nanostructured polymer electrolyte films and enables a platform for future studies that examines the relationship between polymer electrolyte structure and ion transport.« less

  9. Eikonalization of conformal blocks

    DOE PAGES

    Fitzpatrick, A. Liam; Kaplan, Jared; Walters, Matthew T.; ...

    2015-09-03

    Classical field configurations such as the Coulomb potential and Schwarzschild solution are built from the t-channel exchange of many light degrees of freedom. We study the CFT analog of this phenomenon, which we term the 'eikonalization' of conformal blocks. We show that when an operator T appears in the OPE Ο(x)Ο(0), then the large spin Fock space states [TT···T] ℓ also appear in this OPE with a computable coefficient. The sum over the exchange of these Fock space states in an correlator build the classical 'T field' in the dual AdS description. In some limits the sum of all Fockmore » space exchanges can be represented as the exponential of a single T exchange in the 4-pt correlator of O. Our results should be useful for systematizing 1/ℓ perturbation theory in general CFTs and simplifying the computation of large spin OPE coefficients. As examples we obtain the leading log ℓ dependence of Fock space conformal block coefficients, and we directly compute the OPE coefficients of the simplest ‘triple-trace’ operators.« less

  10. UVB-induced epidermal pigmentation in mice eyes with no contact lens wear and non-UVB blocking and UVB blocking contact lens wear.

    PubMed

    Hiramoto, Keiichi; Kobayashi, Hiromi; Yamate, Yurika; Ishii, Masamitsu; Sato, Takao; Inoue, Masayasu

    2013-02-01

    Irradiation by ultraviolet (UV) B is known to increase the number of Dopa-positive melanocytes in the skin. This study examines the effectiveness of a contact lens for the defense of UVB eye irradiation-induced pigmentation. A 2.5 kJ/m(2) dose of UVB radiation was delivered by a sunlamp to the eye of C57BL/6j male mice, and changes in the expression of Dopa-positive melanocytes in the epidermis and the plasma level of alpha-melanocyte-stimulating hormone (α-MSH) was analyzed. The degree of change in the Dopa-positive melanocytes expression was reduced by UVB blocking contact lens using mice given UVB irradiation to the eye. The plasma level of α-MSH increased in the C57BL/6j mice after irradiation to the eye, but there was no increase in the UVB blocking contact lens mice given UVB irradiation to the eye. Both the increase of the expression of Dopa-positive melanocytes and the plasma level of α-MSH were strongly suppressed by an alignment fitting UVB blocking contact lens and only a slightly suspended UVB blocking contact lens. In addition, these changes were successfully inhibited by a UVB blocking contact lens but not by a non-UVB blocking contact lens with a similar absorbance. These observations suggest that the UVB blocking contact lens inhibits the pigmentation of the epidermis in mice by suppressing of the α-MSH. Copyright © 2012 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  11. Guide to Teaching Degrees 2011

    ERIC Educational Resources Information Center

    Adams, Caralee

    2011-01-01

    Getting a master's degree means lots of late nights, busy weekends, and probably taking on student loan debt. The commitment raises the question: Is it worth it? This article takes a comprehensive look at how much a master's is worth, which degree one should pursue, and how one can find a balance in graduate school.

  12. Bayesian block-diagonal variable selection and model averaging

    PubMed Central

    Papaspiliopoulos, O.; Rossell, D.

    2018-01-01

    Summary We propose a scalable algorithmic framework for exact Bayesian variable selection and model averaging in linear models under the assumption that the Gram matrix is block-diagonal, and as a heuristic for exploring the model space for general designs. In block-diagonal designs our approach returns the most probable model of any given size without resorting to numerical integration. The algorithm also provides a novel and efficient solution to the frequentist best subset selection problem for block-diagonal designs. Posterior probabilities for any number of models are obtained by evaluating a single one-dimensional integral, and other quantities of interest such as variable inclusion probabilities and model-averaged regression estimates are obtained by an adaptive, deterministic one-dimensional numerical integration. The overall computational cost scales linearly with the number of blocks, which can be processed in parallel, and exponentially with the block size, rendering it most adequate in situations where predictors are organized in many moderately-sized blocks. For general designs, we approximate the Gram matrix by a block-diagonal matrix using spectral clustering and propose an iterative algorithm that capitalizes on the block-diagonal algorithms to explore efficiently the model space. All methods proposed in this paper are implemented in the R library mombf. PMID:29861501

  13. Morphologic Variability of two Adjacent Mass-Transport Deposits: Twin Slides, Gela Basin (Sicily Channel).

    NASA Astrophysics Data System (ADS)

    Minisini, D.; Trincardi, F.; Asioli, A.; Canu, M.; Foglini, F.

    2006-12-01

    Integrating geophysical, sedimentological, structural and paleontological data, we reconstruct the age, size and internal geometry of two adjacent and recent mass-transport deposits (Twin Slides) exposed on the seafloor of Gela Basin (Sicily Channel). Twin Slides are coeval (late-Holocene), and were likely triggered by an earthquake. Twin Slides originated from the mobilization of Pleistocene slope units, are only 6 km apart from each other, have their headscarps in similar water depth (230 m), and have a comparable run out distance (ca. 10 km). Both slides suggest a multistage evolution, but differ in internal organization and morphological expression. The northern slide shows a deposit characterised by pressure ridges in the toe region suggesting a component of plastic deformation, while the southern slide is characterised by large blocks and a reduced thickness of displaced masses. We ascribe the difference in deformation style and resulting morphology to the stratigraphic architecture of the Pleistocene progradational units involved in failure. In the case of the blocky southern slide the units affected by failure are slightly older (Eemian or pre-Emian) and more consolidated; furthermore, in the area where the headscarp is located these units appear affected by shallow faulting likely resulting in the definition of large blocks. The northern slide, instead, affects progradational units of the Last Glacial Maximum in an area where these units are more than 100 m thick and, possibly, underconsolidated.

  14. Differences in STEM degree attainment by region, ethnicity, and degree type

    NASA Astrophysics Data System (ADS)

    Koledoye, Kimberly A.

    Purpose One purpose of this study was to determine the extent to which a difference was present in the STEM degree attainment of all students and particularly of URMs between the 2001 and the 2009 academic year. The second purpose of this study was to determine the extent to which a difference was present in the attainment of STEM associate degrees and bachelor degrees of all students and particularly of URMs awarded between the 2001 and the 2009 academic year. Another purpose of this study was to determine the extent to which a difference existed in STEM associate degree and STEM bachelor degree attainment among geographic regions between the 2001 and the 2009 academic years. The extent to which a difference existed in the STEM bachelor degree and associate degree attainment of URMs among geographic regions between the 2001 to the 2009 academic year was ascertained. The final purpose of this study was to determine the extent to which a difference was present in STEM associate degree and bachelor degree attainment of all students and particularly URMs as a function of degree type between the 2001 academic year and the 2009 academic year. Methodology Archival data from the Integrated Postsecondary Education Data System were utilized to compare STEM degree attainment for regions, regions for URMs, STEM degree attainment overall and for URMs, STEM degree attainment classified by associate degrees and bachelor degrees for all students and URMs, and STEM degree attainment of associate degrees and bachelor degrees for all students and URMs by specific degree type between 2001 and 2009. Findings In this non-experimental causal comparative investigation, statistically significant differences were revealed in 95 of the 165 comparisons. Declining associate degree attainment was concerning, particularly in the computer and information sciences and engineering and engineering technologies. Moderate increases were determined in bachelor degree attainment with statistically

  15. Flux control and one-hundred and eighty degree core systems

    DOEpatents

    Hsu, John S

    2012-11-27

    A two-phase or four-phase electric machine includes a first stator part and a second stator part disposed about ninety electrical degrees apart. Stator pole parts are positioned near the first stator part and the second stator part. An injector injects a third-harmonic frequency current that is separate from and not produced by the fundamental current driving the first stator part and the second stator part. The electric angular speed of the third-harmonic rotating field comprises .theta. ##EQU00001## where p comprises the number of pole pairs, .theta. comprises a mechanical angle and t comprise time in seconds.

  16. Mean gravity anomalies and sea surface heights derived from GEOS-3 altimeter data

    NASA Technical Reports Server (NTRS)

    Rapp, R. H.

    1978-01-01

    Approximately 2000 GEOS-3 altimeter arcs were analyzed to improve knowledge of the geoid and gravity field. An adjustment procedure was used to fit the sea surface heights (geoid undulations) in an adjustment process that incorporated cross-over constraints. The error model used for the fit was a one or two parameter model which was designed to remove altimeter bias and orbit error. The undulations on the adjusted arcs were used to produce geoid maps in 20 regions. The adjusted data was used to derive 301 5 degree equal area anomalies and 9995 1 x 1 degree anomalies in areas where the altimeter data was most dense, using least squares collocation techniques. Also emphasized was the ability of the altimeter data to imply rapid anomaly changes of up to 240 mgals in adjacent 1 x 1 degree blocks.

  17. Analysis of genome rearrangement by block-interchanges.

    PubMed

    Lu, Chin Lung; Lin, Ying Chih; Huang, Yen Lin; Tang, Chuan Yi

    2007-01-01

    Block-interchanges are a new kind of genome rearrangements that affect the gene order in a chromosome by swapping two nonintersecting blocks of genes of any length. More recently, the study of such rearrangements is becoming increasingly important because of its applications in molecular evolution. Usually, this kind of study requires to solve a combinatorial problem, called the block-interchange distance problem, which is to find a minimum number of block-interchanges between two given gene orders of linear/circular chromosomes to transform one gene order into another. In this chapter, we shall introduce the basics of block-interchange rearrangements and permutation groups in algebra that are useful in analyses of genome rearrangements. In addition, we shall present a simple algorithm on the basis of permutation groups to efficiently solve the block-interchange distance problem, as well as ROBIN, a web server for the online analyses of block-interchange rearrangements.

  18. Non-target adjacent stimuli classification improves performance of classical ERP-based brain computer interface

    NASA Astrophysics Data System (ADS)

    Ceballos, G. A.; Hernández, L. F.

    2015-04-01

    Objective. The classical ERP-based speller, or P300 Speller, is one of the most commonly used paradigms in the field of Brain Computer Interfaces (BCI). Several alterations to the visual stimuli presentation system have been developed to avoid unfavorable effects elicited by adjacent stimuli. However, there has been little, if any, regard to useful information contained in responses to adjacent stimuli about spatial location of target symbols. This paper aims to demonstrate that combining the classification of non-target adjacent stimuli with standard classification (target versus non-target) significantly improves classical ERP-based speller efficiency. Approach. Four SWLDA classifiers were trained and combined with the standard classifier: the lower row, upper row, right column and left column classifiers. This new feature extraction procedure and the classification method were carried out on three open databases: the UAM P300 database (Universidad Autonoma Metropolitana, Mexico), BCI competition II (dataset IIb) and BCI competition III (dataset II). Main results. The inclusion of the classification of non-target adjacent stimuli improves target classification in the classical row/column paradigm. A gain in mean single trial classification of 9.6% and an overall improvement of 25% in simulated spelling speed was achieved. Significance. We have provided further evidence that the ERPs produced by adjacent stimuli present discriminable features, which could provide additional information about the spatial location of intended symbols. This work promotes the searching of information on the peripheral stimulation responses to improve the performance of emerging visual ERP-based spellers.

  19. 31 CFR 598.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... 598.301 Section 598.301 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS General Definitions § 598.301 Blocked account; blocked property. The terms blocked account and blocked property mean any account or property subject to § 598.202 held in the name of a specially...

  20. Open-door laminoplasty for cervical myelopathy resulting from adjacent-segment disease in patients with previous anterior cervical decompression and fusion.

    PubMed

    Matsumoto, Morio; Nojiri, Kenya; Chiba, Kazuhiro; Toyama, Yoshiaki; Fukui, Yasuyuki; Kamata, Michihiro

    2006-05-20

    This is a retrospective study of patients with cervical myelopathy resulting from adjacent-segment disease who were treated by open-door expansive laminoplasty. The purpose of this study was to evaluate the effectiveness of laminoplasty for cervical myelopathy resulting from adjacent-segment disease. Adjacent-segment disease is one of the problems associated with anterior cervical decompression and fusion. However, the optimal surgical management strategy is still controversial. Thirty-one patients who underwent open-door expansive laminoplasty for cervical myelopathy resulting from adjacent-segment disease and age- and sex-matched 31 patients with myelopathy who underwent laminoplasty as the initial surgery were enrolled in the study. The pre- and postoperative Japanese Orthopedic Association scores (JOA scores) and the recovery rate were compared between the two groups. The average JOA scores in the patients with adjacent-segment disease and the controls were 9.2 +/- 2.6 and 9.4 +/- 2.3 before the expansive laminoplasty and 11.9 +/- 2.8 and 13.3 +/- 1.7 at the follow-up examination, respectively; the average recovery rates in the two groups were 37.1 +/- 22.4% and 50.0 +/- 21.3%, respectively (P = 0.04). The mean number of segments covered by the high-intensity lesions on the T2-weighted magnetic resonance images was 1.87 and 0.9, respectively (P = 0.001). Moderate neurologic recovery was obtained after open-door laminoplasty in patients with cervical myelopathy resulting from adjacent-segment disc disease, although the results were not as satisfactory as those in the control group. This may be attributed to the irreversible damage of the spinal cord caused by persistent compression at the adjacent segments.

  1. Monolithic laser diode array with one metalized sidewall

    DOEpatents

    Freitas, Barry L.; Skidmore, Jay A.; Wooldridge, John P.; Emanuel, Mark A.; Payne, Stephen A.

    2001-01-01

    A monolithic, electrically-insulating substrate that contains a series of notched grooves is fabricated. The substrate is then metalized so that only the top surface and one wall adjacent to the notch are metalized. Within the grooves is located a laser bar, an electrically-conductive ribbon or contact bar and an elastomer which secures/registers the laser bar and ribbon (or contact bar) firmly along the wall of the groove that is adjacent to the notch. The invention includes several embodiments for providing electrical contact to the corresponding top surface of the adjacent wall. In one embodiment, after the bar is located in the proper position, the electrically conductive ribbon is bent so that it makes electrical contact with the adjoining metalized top side of the heatsink.

  2. A novel 360-degree shape measurement using a simple setup with two mirrors and a laser MEMS scanner

    NASA Astrophysics Data System (ADS)

    Jin, Rui; Zhou, Xiang; Yang, Tao; Li, Dong; Wang, Chao

    2017-09-01

    There is no denying that 360-degree shape measurement technology plays an important role in the field of threedimensional optical metrology. Traditional optical 360-degree shape measurement methods are mainly two kinds: the first kind, by placing multiple scanners to achieve 360-degree measurements; the second kind, through the high-precision rotating device to get 360-degree shape model. The former increases the number of scanners and costly, while the latter using rotating devices lead to time consuming. This paper presents a low cost and fast optical 360-degree shape measurement method, which possesses the advantages of full static, fast and low cost. The measuring system consists of two mirrors with a certain angle, a laser projection system, a stereoscopic calibration block, and two cameras. And most of all, laser MEMS scanner can achieve precise movement of laser stripes without any movement mechanism, improving the measurement accuracy and efficiency. What's more, a novel stereo calibration technology presented in this paper can achieve point clouds data registration, and then get the 360-degree model of objects. A stereoscopic calibration block with special coded patterns on six sides is used in this novel stereo calibration method. Through this novel stereo calibration technology we can quickly get the 360-degree models of objects.

  3. HEAO Block 2 study executive summary

    NASA Technical Reports Server (NTRS)

    1976-01-01

    An executive summary is presented of a preliminary study done on several potential High Energy Astronomy Observatory (HEAO) missions which are follow-on missions to the currently defined HEAO program. The purpose was to examine several typical missions and determine the relative complexities associated with them. The four payloads investigated were (1) a 1.2 m Diameter X-ray Telescope observatory, (2) a Large Area Moderate Angular Resolution (LAMAR) observatory, (3) a cosmic ray observatory, and (4) a gamma ray observatory. Each of the four observatories was considered a national facility. Low cost approaches were stressed throughout, with considerable use of HEAO Block I experience and designs effected to provide a high degree of confidence that such approaches were achievable. The use of the Multi-Mission Spacecraft (MMS) and the HEAO Block I spacecraft was considered as a result of this low cost emphasis. Also, NASA standard components were considered, where applicable.

  4. 33 CFR 334.730 - Waters of Santa Rosa Sound and Gulf of Mexico adjacent to Santa Rosa Island, Armament Center...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Gulf of Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. 334.730... Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. (a) The areas—(1) The... CFR part 329, including the waters of Santa Rosa Sound and Gulf of Mexico within a circle one nautical...

  5. 33 CFR 334.730 - Waters of Santa Rosa Sound and Gulf of Mexico adjacent to Santa Rosa Island, Armament Center...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Gulf of Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. 334.730... Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. (a) The areas—(1) The... CFR part 329, including the waters of Santa Rosa Sound and Gulf of Mexico within a circle one nautical...

  6. 33 CFR 334.730 - Waters of Santa Rosa Sound and Gulf of Mexico adjacent to Santa Rosa Island, Armament Center...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Gulf of Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. 334.730... Mexico adjacent to Santa Rosa Island, Armament Center, Eglin Air Force Base, Fla. (a) The areas—(1) The... CFR part 329, including the waters of Santa Rosa Sound and Gulf of Mexico within a circle one nautical...

  7. Functionalized Helical Building Blocks for Nanoelectronics.

    PubMed

    Khokhlov, Khrystofor; Schuster, Nathaniel J; Ng, Fay; Nuckolls, Colin

    2018-04-06

    Molecular building blocks are designed and created for the cis- and trans-dibrominated perylenediimides. The syntheses are simple and provide these useful materials on the gram scale. To demonstrate their synthetic versatility, these building blocks were used to create new dimeric perylenediimide helixes. Two of these helical dimers are twistacenes, and one is a helicene. Crucially, each possesses regiochemically defined functionality that allows the dimer helix to be elaborated into higher oligomers. It would be very difficult to prepare these helical PDI building blocks regioselectively without the methods described.

  8. Microbial production of polyhydroxyalkanoate block copolymer by recombinant Pseudomonas putida.

    PubMed

    Li, Shi Yan; Dong, Cui Ling; Wang, Shen Yu; Ye, Hai Mu; Chen, Guo-Qiang

    2011-04-01

    Polyhydroxyalkanoate (PHA) synthesis genes phaPCJ(Ac) cloned from Aeromonas caviae were transformed into Pseudomonas putida KTOY06ΔC, a mutant of P. putida KT2442, resulting in the ability of the recombinant P. putida KTOY06ΔC (phaPCJ(A.c)) to produce a short-chain-length and medium-chain-length PHA block copolymer consisting of poly-3-hydroxybutyrate (PHB) as one block and random copolymer of 3-hydroxyvalerate (3HV) and 3-hydroxyheptanoate (3HHp) as another block. The novel block polymer was studied by differential scanning calorimetry (DSC), nuclear magnetic resonance, and rheology measurements. DSC studies showed the polymer to possess two glass transition temperatures (T(g)), one melting temperature (T(m)) and one cool crystallization temperature (T(c)). Rheology studies clearly indicated a polymer chain re-arrangement in the copolymer; these studies confirmed the polymer to be a block copolymer, with over 70 mol% homopolymer (PHB) of 3-hydroxybutyrate (3HB) as one block and around 30 mol% random copolymers of 3HV and 3HHp as the second block. The block copolymer was shown to have the highest tensile strength and Young's modulus compared with a random copolymer with similar ratio and a blend of homopolymers PHB and PHVHHp with similar ratio. Compared with other commercially available PHA including PHB, PHBV, PHBHHx, and P3HB4HB, the short-chain- and medium-chain-length block copolymer PHB-b-PHVHHp showed differences in terms of mechanical properties and should draw more attentions from the PHA research community. © Springer-Verlag 2010

  9. Variable length adjacent partitioning for PTS based PAPR reduction of OFDM signal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ibraheem, Zeyid T.; Rahman, Md. Mijanur; Yaakob, S. N.

    2015-05-15

    Peak-to-Average power ratio (PAPR) is a major drawback in OFDM communication. It leads the power amplifier into nonlinear region operation resulting into loss of data integrity. As such, there is a strong motivation to find techniques to reduce PAPR. Partial Transmit Sequence (PTS) is an attractive scheme for this purpose. Judicious partitioning the OFDM data frame into disjoint subsets is a pivotal component of any PTS scheme. Out of the existing partitioning techniques, adjacent partitioning is characterized by an attractive trade-off between cost and performance. With an aim of determining effects of length variability of adjacent partitions, we performed anmore » investigation into the performances of a variable length adjacent partitioning (VL-AP) and fixed length adjacent partitioning in comparison with other partitioning schemes such as pseudorandom partitioning. Simulation results with different modulation and partitioning scenarios showed that fixed length adjacent partition had better performance compared to variable length adjacent partitioning. As expected, simulation results showed a slightly better performance of pseudorandom partitioning technique compared to fixed and variable adjacent partitioning schemes. However, as the pseudorandom technique incurs high computational complexities, adjacent partitioning schemes were still seen as favorable candidates for PAPR reduction.« less

  10. Doxorubicin-induced second degree and complete atrioventricular block.

    PubMed

    Kilickap, Saadettin; Akgul, Ebru; Aksoy, Sercan; Aytemir, Kudret; Barista, Ibrahim

    2005-05-01

    Doxorubicin is one of the most effective chemotherapeutic agents used in the treatment of malignancies. Cardiotoxicity is the most important dose-limiting toxicity of doxorubicin. Although cardiomyopathy is the most well known side effect of doxorubicin, it usually occurs many years after the treatment and relates to cumulative doxorubicin dosage. Another form of doxorubicin cardiotoxicity is arrhythmia which may occur at any time and after any dosage. However, doxorubicin-induced arrhythmia is rarely a life-threatening side effect. In this report, we present a case in which there were doxorubicin-induced life-threatening arrhythmias.

  11. Active lower limb orthosis with one degree of freedom for people with paraplegia.

    PubMed

    Gloger, Michal; Obinata, Goro; Genda, Eiichi; Babjak, Jan; Pei, Yanling

    2017-07-01

    The main challenges of designing devices for paraplegic walking can be summarized into three groups, stability and comfort, high efficiency or low energy consumption, dimensions and weight. A new economical device for people with paraplegia which tackles all problems of the three groups is introduced in this paper. The main idea of this device is based on HALO mechanism. HALO is compact passive medial hip joint orthosis with contralateral hip and ankle linkage, which keeps the feet always parallel to the ground and assists swinging the leg. The medial hip joint is equipped with one actuator in the new design and the new orthosis is called @halo. Due to this update, we can achieve more stable and smoother walking patterns with decreased energy consumption of the users, yet maintain its compact and lightweight features. It is proven by the results from preliminary experiments with able-bodied subjects during which the same device with and without actuator was evaluated. Waddling and excessive vertical elevation of the center of gravity were decreased by 40% with significantly smaller standard deviations in case of the active orthosis. There was 52% less energy spent by the user wearing @halo which was calculated from the vertical excursion difference. There was measured 38.5% bigger impulse in crutches while using passive orthosis. The new @halo device is the first active orthosis for lower limbs with just one actuated degree of freedom for users with paraplegia.

  12. HIS bundle electrogram in rheumatic mitral valve disease with special reference to Bachmann's bundle block in P mitrale.

    PubMed

    Lee, Y S; Lien, W P

    1975-08-01

    HBEs were recorded from either the right or left ventricle or simultaneously from both in 26 patients with chronic rheumatic mitral stenosis alone or in association with other mild valvular lesions during the diagnostic cardiac catheterization. Eleven of the patients had auricular fibrillation. Of the remaining 15 patients with sinus mechanism and P mitrale in the surface electrocardiogram, 12 were noted to have H potential preceded the termination of P wave and gave P2H interval of negative value- so-called "Bachmann's bundle block". Among these, double atrial activities (A and A' waves) could be identified on the HBE recorded from the left ventricular endocardial surface with catheter electrodes positioned at the subarotic region in 7 patients studied. Interatrial conduction time (P1A' interval) measured in these patients was prolonged in all and ranged from 47 to 82 with an average of 66 msec. Prolongation of intraatrial (or internodal) conduction time was noted in only one patient who also had first degree A-V block and prolonged A-H interval. There was no correlation of either P1P2 or P2H interval to the degree of left atrial enlargement. The P1P2 or P2H interval also had no correlation with hemodynamic parameters. In patients with auricular fibrillation, all impulses unable to conduct to the ventricle were blocked proximal to the His bundle and concealed conduction was not observed distal to it.

  13. An easy access to 2-Amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: the reaction under conventional and microwave conditions.

    PubMed

    Ostras, Konstantin S; Gorobets, Nikolay Yu; Desenko, Sergey M; Musatov, Vladimir I

    2006-08-01

    A new one-stage fast multicomponent synthesis of title compounds leads to products in 21-55% isolated yields under both conventional and microwave conditions. The primary amino group in the building blocks can be easily acylated by various usual electophilic agents that can be utilized in the synthesis of diverse heterocylic compounds libraries.

  14. Long-term effects of vertebroplasty: adjacent vertebral fractures.

    PubMed

    Baroud, Gamal; Vant, Christianne; Wilcox, Ruth

    2006-01-01

    In today's aging population, osteoporosis-related fractures are an ever-growing concern. Vertebroplasty, a promising yet cost-effective treatment for vertebral compression fractures, has an increasing role. The first vertebroplasty procedures were reported by Deramond and Galibert in France in 1987, and international interest grew with continued development of clinical techniques and augmentation materials in Europe and the United States. Initial publications and presentations at peer review meetings demonstrated 60-90% success rates in providing immediate and significant pain relief. The objective of this review is to assemble experimental and computational biomechanical research whose goal is determining and preventing the negative long-term effects ofvertebroplasty, with a specific focus on adjacent vertebral fractures. Biomechanical studies using isolated cancellous bone cylinders have shown that osteoporotic cancellous bone samples augmented by the rigid bone cement were at least 12 times stiffer and 35 times stronger than the untreated osteoporotic cancellous bone samples. The biomechanical efficacy of the procedure to repair the fractured vertebrae and prevent further collapse is determined using single-vertebra models. The strength or load-bearing capacity of a single vertebra is significantly increased following augmentation when compared to the intact strength. However, there is no dear result regarding the overall stiffness of the single vertebra, with studies reporting contradictorily that the stiffness increases, decreases, or does not significantly alter following augmentation. The effects of vertebroplasty on adjacent structures are studied via multisegment models, whose results plainly oppose the findings of the single-vertebra and intravertebral models. Here, augmentation was shown to decrease the overall segment strength by 19% when compared to the matched controls. As well, there is a significant increase in disc pressure compared to the pre

  15. Adjacent slice prostate cancer prediction to inform MALDI imaging biomarker analysis

    NASA Astrophysics Data System (ADS)

    Chuang, Shao-Hui; Sun, Xiaoyan; Cazares, Lisa; Nyalwidhe, Julius; Troyer, Dean; Semmes, O. John; Li, Jiang; McKenzie, Frederic D.

    2010-03-01

    Prostate cancer is the second most common type of cancer among men in US [1]. Traditionally, prostate cancer diagnosis is made by the analysis of prostate-specific antigen (PSA) levels and histopathological images of biopsy samples under microscopes. Proteomic biomarkers can improve upon these methods. MALDI molecular spectra imaging is used to visualize protein/peptide concentrations across biopsy samples to search for biomarker candidates. Unfortunately, traditional processing methods require histopathological examination on one slice of a biopsy sample while the adjacent slice is subjected to the tissue destroying desorption and ionization processes of MALDI. The highest confidence tumor regions gained from the histopathological analysis are then mapped to the MALDI spectra data to estimate the regions for biomarker identification from the MALDI imaging. This paper describes a process to provide a significantly better estimate of the cancer tumor to be mapped onto the MALDI imaging spectra coordinates using the high confidence region to predict the true area of the tumor on the adjacent MALDI imaged slice.

  16. Global Precipitation at One-Degree Daily Resolution From Multi-Satellite Observations

    NASA Technical Reports Server (NTRS)

    Huffman, George J.; Adler, Robert F.; Morrissey, Mark M.; Curtis, Scott; Joyce, Robert; McGavock, Brad; Susskind, Joel

    2000-01-01

    The One-Degree Daily (1DD) technique is described for producing globally complete daily estimates of precipitation on a 1 deg x 1 deg lat/long grid from currently available observational data. Where possible (40 deg N-40 deg S), the Threshold-Matched Precipitation Index (TMPI) provides precipitation estimates in which the 3-hourly infrared brightness temperatures (IR T(sub b)) are thresholded and all "cold" pixels are given a single precipitation rate. This approach is an adaptation of the Geostationary Operational Environmental Satellite (GOES) Precipitation Index (GPI), but for the TMPI the IR Tb threshold and conditional rain rate are set locally by month from Special Sensor Microwave/Imager (SSM/I)-based precipitation frequency and the Global Precipitation Climatology Project (GPCP) satellite-gauge (SG) combined monthly precipitation estimate, respectively. At higher latitudes the 1DD features a rescaled daily Television Infrared Observation Satellite (TIROS) Operational Vertical Sounder (TOVS) precipitation. The frequency of rain days in the TOVS is scaled down to match that in the TMPI at the data boundaries, and the resulting non-zero TOVS values are scaled locally to sum to the SG (which is a globally complete monthly product). The time series of the daily 1DD global images shows good continuity in time and across the data boundaries. Various examples are shown to illustrate uses. Validation for individual grid -box values shows a very high root-mean-square error but, it improves quickly when users perform time/space averaging according to their own requirements.

  17. Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA.

    PubMed

    Guo, Shicheng; Diep, Dinh; Plongthongkum, Nongluk; Fung, Ho-Lim; Zhang, Kang; Zhang, Kun

    2017-04-01

    Adjacent CpG sites in mammalian genomes can be co-methylated owing to the processivity of methyltransferases or demethylases, yet discordant methylation patterns have also been observed, which are related to stochastic or uncoordinated molecular processes. We focused on a systematic search and investigation of regions in the full human genome that show highly coordinated methylation. We defined 147,888 blocks of tightly coupled CpG sites, called methylation haplotype blocks, after analysis of 61 whole-genome bisulfite sequencing data sets and validation with 101 reduced-representation bisulfite sequencing data sets and 637 methylation array data sets. Using a metric called methylation haplotype load, we performed tissue-specific methylation analysis at the block level. Subsets of informative blocks were further identified for deconvolution of heterogeneous samples. Finally, using methylation haplotypes we demonstrated quantitative estimation of tumor load and tissue-of-origin mapping in the circulating cell-free DNA of 59 patients with lung or colorectal cancer.

  18. Large Block Test Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, W

    2001-12-01

    This report documents the Large-Block Test (LBT) conducted at Fran Ridge near Yucca Mountain, Nevada. The LBT was a thermal test conducted on an exposed block of middle non-lithophysal Topopah Spring tuff (Tptpmn) and was designed to assist in understanding the thermal-hydrological-mechanical-chemical (THMC) processes associated with heating and then cooling a partially saturated fractured rock mass. The LBT was unique in that it was a large (3 x 3 x 4.5 m) block with top and sides exposed. Because the block was exposed at the surface, boundary conditions on five of the six sides of the block were relatively wellmore » known and controlled, making this test both easier to model and easier to monitor. This report presents a detailed description of the test as well as analyses of the data and conclusions drawn from the test. The rock block that was tested during the LBT was exposed by excavation and removal of the surrounding rock. The block was characterized and instrumented, and the sides were sealed and insulated to inhibit moisture and heat loss. Temperature on the top of the block was also controlled. The block was heated for 13 months, during which time temperature, moisture distribution, and deformation were monitored. After the test was completed and the block cooled down, a series of boreholes were drilled, and one of the heater holes was over-cored to collect samples for post-test characterization of mineralogy and mechanical properties. Section 2 provides background on the test. Section 3 lists the test objectives and describes the block site, the site configuration, and measurements made during the test. Section 3 also presents a chronology of events associated with the LBT, characterization of the block, and the pre-heat analyses of the test. Section 4 describes the fracture network contained in the block. Section 5 describes the heating/cooling system used to control the temperature in the block and presents the thermal history of the block during the

  19. Electrophysiologic and histologic observations of chronic atrioventricular block induced by closed-chest catheter desiccation with radiofrequency energy.

    PubMed

    Huang, S K; Bharati, S; Lev, M; Marcus, F I

    1987-07-01

    Direct-current or laser energy has been used to induce atrioventricular (AV) block, but certain complications associated with this type of energy have been reported. We have previously documented that radiofrequency (RF) energy can effectively and safely induce acute AV block in closed-chest dogs during the 4-7 days of follow-up. This study was undertaken to determine if the ablation was permanent and to define the chronic pathology and site of AV block. Complete AV block was successfully achieved in four dogs immediately after ablation with a bipolar "standard" RF output (750 kHz) delivered between the tip electrode of a standard 7F USCI catheter and an external patch electrode on the left lateral chest wall. During 2 months of follow-up, three dogs had persistent complete AV block with a stable escape rhythm; the other had persistent 2:1 AV block. Repeat His bundle recordings were performed at 2 months prior to sacrifice of the dogs. Supra-His AV block was noted in two dogs; His bundle potential could not be recorded in another two. Histologically, the damaged area was well delineated. In all animals, the AV node and, in some dogs, part of the His bundle were completely replaced by granulation tissue and/or cartilage. There was fatty infiltration and also chronic inflammatory cells around the lesions. Neither perforation, hemorrhage nor vacuolation was seen in the adjacent area. Thrombus was not present. It is concluded that RF energy can effectively achieve chronic AV block and produce well-circumscribed pathological lesions.

  20. Advantages of caudal block over intrarectal local anesthesia plus periprostatic nerve block for transrectal ultrasound guided prostate biopsy

    PubMed Central

    Wang, Na; Fu, Yaowen; Ma, Haichun; Wang, Jinguo; Gao, Yang

    2016-01-01

    Objective: To compare caudal block with intrarectal local anesthesia plus periprostatic nerve block for transrectal ultrasound guided prostate biopsy. Methods: One hundred and ninety patients scheduled for transrectal ultrasound guided prostate biopsy were randomized equally into Group-A who received caudal block (20 ml 1.2% lidocaine) and Group-B who received intrarectal local anesthesia (0.3% oxybuprocaine cream) plus periprostatic nerve block (10 ml 1% lidocaine plus 0.5% ropivacaine) before biopsy. During and after the procedure, the patients rated the level of pain/discomfort at various time points. Complications during the whole study period and the patient overall satisfaction were also evaluated. Results: More pain and discomfort was detected during periprostatic nerve block than during caudal block. Pain and discomfort was significantly lower during prostate biopsy and during the manipulation of the probe in the rectum in Group-A than in Group-B. No significant differences were detected in the pain intensity after biopsy and side effects between the two groups. Conclusions: Caudal block provides better anesthesia than periprostatic nerve block plus intrarectal local anesthesia for TRUS guided prostate biopsy without an increase of side effects. PMID:27648052

  1. Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides.

    PubMed

    Weitzhandler, Isaac; Dzuricky, Michael; Hoffmann, Ingo; Garcia Quiroz, Felipe; Gradzielski, Michael; Chilkoti, Ashutosh

    2017-08-14

    Reported here is the synthesis of perfectly sequence defined, monodisperse diblock copolypeptides of hydrophilic elastin-like and hydrophobic resilin-like polypeptide blocks and characterization of their self-assembly as a function of structural parameters by light scattering, cryo-TEM, and small-angle neutron scattering. A subset of these diblock copolypeptides exhibit lower critical solution temperature and upper critical solution temperature phase behavior and self-assemble into spherical or cylindrical micelles. Their morphologies are dictated by their chain length, degree of hydrophilicity, and hydrophilic weight fraction of the ELP block. We find that (1) independent of the length of the corona-forming ELP block there is a minimum threshold in the length of the RLP block below which self-assembly does not occur, but that once that threshold is crossed, (2) the RLP block length is a unique molecular parameter to independently tune self-assembly and (3) increasing the hydrophobicity of the corona-forming ELP drives a transition from spherical to cylindrical morphology. Unlike the self-assembly of purely ELP-based block copolymers, the self-assembly of RLP-ELPs can be understood by simple principles of polymer physics relating hydrophilic weight fraction and polymer-polymer and polymer-solvent interactions to micellar morphology, which is important as it provides a route for the de novo design of desired nanoscale morphologies from first principles.

  2. Explaining large mortality differences between adjacent counties: a cross-sectional study.

    PubMed

    Schootman, M; Chien, L; Yun, S; Pruitt, S L

    2016-08-02

    Extensive geographic variation in adverse health outcomes exists, but global measures ignore differences between adjacent geographic areas, which often have very different mortality rates. We describe a novel application of advanced spatial analysis to 1) examine the extent of differences in mortality rates between adjacent counties, 2) describe differences in risk factors between adjacent counties, and 3) determine if differences in risk factors account for the differences in mortality rates between adjacent counties. We conducted a cross-sectional study in Missouri, USA with 2005-2009 age-adjusted all-cause mortality rate as the outcome and county-level explanatory variables from a 2007 population-based survey. We used a multi-level Gaussian model and a full Bayesian approach to analyze the difference in risk factors relative to the difference in mortality rates between adjacent counties. The average mean difference in the age-adjusted mortality rate between any two adjacent counties was -3.27 (standard deviation = 95.5) per 100,000 population (maximum = 258.80). Six variables were associated with mortality differences: inability to obtain medical care because of cost (β = 2.6), hospital discharge rate (β = 1.03), prevalence of fair/poor health (β = 2.93), and hypertension (β = 4.75) and poverty prevalence (β = 6.08). Examining differences in mortality rates and associated risk factors between adjacent counties provides additional insight for future interventions to reduce geographic disparities.

  3. Resilient self-assembling hydrogels from block copolypeptide amphiphiles

    NASA Astrophysics Data System (ADS)

    Nowak, Andrew Paul

    The ability to produce well defined synthetic polypeptides has been greatly improved by the discovery of transition metal species that mediate the controlled polymerization of N-carboxyanhydrides (NCAs). These metal species create a living polymerization system by producing control over chain length, low polydispersities, and the ability to form complex block architectures. We have applied this system to the synthesis of block copolypeptide amphiphiles. Initial block copolymers synthesized were composed of hydrophilic, cationic poly(L-Lysine) combined with hydrophobic, alpha-helical poly(L-Leucine). These Lysine- block-Leucine copolypeptides were found to form stiff, clear hydrogels at low concentration (˜1 wt%) in low ionic strength water. Based on this unexpected result we used the flexibility of our transition metal polymerization chemistry to better understand the nature and mechanisms of gel formation in these materials. Systematic changes to the original Lysine-block-Leucine copolypeptides were made by altering overall chain size, relative block length, polyelectrolyte charge, and hydrophobic secondary structure. Rheological characterization revealed that the strength of these hydrogels was primarily dependent on degree of polymerization, relative block length, and a well ordered secondary structure in the hydrophobic segment. The Lysine-block-Leucine hydrogels were formed by direct addition of water to dry polypeptide material which swelled to homogeneously fill the entire volume of liquid with no special processing. CryoTEM showed a percolating cellular network at ˜100nm that appears to be comprised of both membranes and fibers. Larger length scales studied with Laser Scanning Confocal Microscopy revealed a spontaneously formed microporous network with large (˜10mum) water rich voids. These hydrogels also displayed interesting mechanical properties including rapid recovery of solid like behavior after being sheared to a liquid and mechanical stability

  4. Vertebral Augmentation can Induce Early Signs of Degeneration in the Adjacent Intervertebral Disc: Evidence from a Rabbit Model.

    PubMed

    Feng, Zhiyun; Chen, Lunhao; Hu, Xiaojian; Yang, Ge; Wang, Yue; Chen, Zhong

    2018-04-11

    An experimental study. The aim of this study was to determine the effect of polymethylmethacrylate (PMMA) augmentation on the adjacent disc. Vertebral augmentation with PMMA reportedly may predispose the adjacent vertebra to fracture. The influence of PMMA augmentation on the adjacent disc, however, remains unclear. Using a retroperitoneal approach, PMMA augmentation was performed for 23 rabbits. For each animal, at least one vertebra was augmented with 0.2 to 0.3 mL PMMA. The disc adjacent to the augmented vertebra and a proximal control disc were studied using magnetic resonance (MR) imaging, histological and molecular level evaluation at 1, 3, and 6 months postoperatively. Marrow contact channels in the endplate were quantified in histological slices and number of invalid channels (those without erythrocytes inside) was rated. Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) was performed to determine disc cell apoptosis. On MR images, the signal and height of the adjacent disc did not change 6 months after vertebral augmentation. Histological scores of the adjacent disc increased over time, particularly for the nucleus pulposus. The adjacent disc had greater nucleus degeneration score than the control disc at 3 months (5.7 vs. 4.5, P < 0.01) and 6 months (6.9 vs. 4.4, P < 0.001). There were more invalid marrow contact channels in the endplate of augmented vertebra than the control (43.3% vs. 11.1%, P < 0.01). mRNA of ADAMTS-5, MMP-13, HIF-1α, and caspase-3 were significantly upregulated in the adjacent disc at 3 and 6 months (P < 0.05 for all). In addition, there were more TUNEL-positive cells in the adjacent disc than in the control disc (43.4% vs. 24.0%, P < 0.05) at 6 months postoperatively. Vertebral augmentation can induce early degenerative signs in the adjacent disc, which may be due to impaired nutrient supply to the disc. N/A.

  5. Nalbuphine as an adjuvant to 0.25% levobupivacaine in ultrasound-guided supraclavicular block provided prolonged sensory block and similar motor block durations (RCT).

    PubMed

    Abdelhamid, Bassant Mohamed; Omar, Heba

    2018-05-28

    Prolonged postoperative analgesia with early motor recovery for early rehabilitation is a challenge in regional block. The purpose of this study is to evaluate the effect of adding 20 mg nalbuphine to 25 ml of 0.25% levobupivacaine in supraclavicular brachial plexus block. One hundred thirty-five (135) patients scheduled for hand and forearm surgeries with supraclavicular block were randomly allocated into three equal groups. Group L received 25 ml of 0.5% levobupivacaine + 1 ml normal saline; group H received 25 ml of 0.25% levobupivacaine + 1 ml normal saline; and group N received 25 ml of 0.25% levobupivacaine + 1 ml (20 mg) nalbuphine. Onset time and duration of sensory and motor block, and time to first analgesic dose were recorded. Sensory block onset was comparable between the three groups. Motor block onset in group L and group N was comparable (13.16 ± 3.07 and 13.84 ± 3.05 min, respectively) and was shorter than that in group H (15.71 ± 2 0.91 min). Sensory block duration in group L and group N was comparable (522.22 ± 69.57 and 533.78 ± 66.03 min, respectively) and was longer than that in group H (342.67 ± 92.80 min). Motor block duration in group N and group H was comparable (272.00 ± 59.45 and 249.78 ± 66.01 min, respectively) and was shorter than that in group L (334.67 ± 57.90 min). Time to first analgesic dose was significantly longer in group N (649.78 ± 114.76 min) than that of group L and group H (575.56 ± 96.85 and 375.56 ± 84.49 min, respectively) and longer in group L when compared to group H. Adding 20 mg nalbuphine to 25 ml of 0.25% levobupivacaine in supraclavicular block provided prolonged duration of sensory block with similar duration of motor block.

  6. 78 FR 31631 - Designation of One (1) Individual Pursuant to Executive Orders 13572 of April 29, 2011, “Blocking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... to Human Rights Abuses in Syria'' and 13573 of May 18, 2011, ``Blocking Property of Senior Officials... 13572 of April 29, 2011, ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in...

  7. A comparison between caudal block versus splash block for postoperative analgesia following inguinal herniorrhaphy in children

    PubMed Central

    Cheon, Jun Kong; Hwang, Kan Taeck; Choi, Bo Yoon

    2011-01-01

    Background We wanted to determine the postoperative analgesic efficacy of preincisional caudal epidural block versus instillation (splash block) following inguinal herniorrhaphy in children. Methods Thirty children (age range: 1-7 years) who were scheduled to undergo inguinal herniorrhaphy were divided into 2 groups: the caudal block group and the splash block group with 15 children in each group. Tracheal intubation was performed. Fifteen children received caudal block with 1.0 ml/kg of 0.25% ropivacaine (Group 1). Caudal block was performed using the loss of resistance method via the sacral hiatus. Fifteen children in Group 2 received local instillation (splash block) in the surgical site with up to 0.4 ml/kg of 0.25% ropivacaine. The patients were observed for 90 minutes in the postanesthesia care unit and then they were transferred to the ward. The pain scores were taken 4 times. We assessed pain using the Faces pain scores. Results There were no significant differences between the groups regarding the pain scores at 10, 30 and 60 minutes upon entering the postanesthesia care unit. The pain scores of Group 1 were slightly lower at the last evaluation point when compared to that of Group 2. One patient in Group 1 required supplemental postoperative intravenous (IV) tramadol, while all the other patients in both groups did not require supplemental IV tramadol. The intraoperative requirement for sevoflurane was decreased in Group 1 as compared to that of Group 2. There were no major complications related to either type of block. Conclusions We conclude that a splash block can have a similar analgesic effect as that of a caudal block for the postoperative herniorrhaphy pain of children. PMID:21602975

  8. A comparison between caudal block versus splash block for postoperative analgesia following inguinal herniorrhaphy in children.

    PubMed

    Cheon, Jun Kong; Park, Cheon Hee; Hwang, Kan Taeck; Choi, Bo Yoon

    2011-04-01

    We wanted to determine the postoperative analgesic efficacy of preincisional caudal epidural block versus instillation (splash block) following inguinal herniorrhaphy in children. THIRTY CHILDREN (AGE RANGE: 1-7 years) who were scheduled to undergo inguinal herniorrhaphy were divided into 2 groups: the caudal block group and the splash block group with 15 children in each group. Tracheal intubation was performed. Fifteen children received caudal block with 1.0 ml/kg of 0.25% ropivacaine (Group 1). Caudal block was performed using the loss of resistance method via the sacral hiatus. Fifteen children in Group 2 received local instillation (splash block) in the surgical site with up to 0.4 ml/kg of 0.25% ropivacaine. The patients were observed for 90 minutes in the postanesthesia care unit and then they were transferred to the ward. The pain scores were taken 4 times. We assessed pain using the Faces pain scores. There were no significant differences between the groups regarding the pain scores at 10, 30 and 60 minutes upon entering the postanesthesia care unit. The pain scores of Group 1 were slightly lower at the last evaluation point when compared to that of Group 2. One patient in Group 1 required supplemental postoperative intravenous (IV) tramadol, while all the other patients in both groups did not require supplemental IV tramadol. The intraoperative requirement for sevoflurane was decreased in Group 1 as compared to that of Group 2. There were no major complications related to either type of block. We conclude that a splash block can have a similar analgesic effect as that of a caudal block for the postoperative herniorrhaphy pain of children.

  9. Constrained and Unconstrained Partial Adjacent Category Logit Models for Ordinal Response Variables

    ERIC Educational Resources Information Center

    Fullerton, Andrew S.; Xu, Jun

    2018-01-01

    Adjacent category logit models are ordered regression models that focus on comparisons of adjacent categories. These models are particularly useful for ordinal response variables with categories that are of substantive interest. In this article, we consider unconstrained and constrained versions of the partial adjacent category logit model, which…

  10. Blocking a Redundant Cue: What does it say about preschoolers’ causal competence?

    PubMed Central

    Kloos, Heidi; Sloutsky, Vladimir M.

    2013-01-01

    The current study investigates the degree to which preschoolers can engage in causal inferences in blocking paradigm, a paradigm in which a cue is consistently linked with a target, either alone (A-T) or paired with another cue (AB-T). Unlike previous blocking studies with preschoolers, we manipulated the causal structure of the events without changing the specific contingencies. In particular, cues were said to be either potential causes (prediction condition), or they were said to be potential effects (diagnosis condition). The causally appropriate inference is to block the redundant cue B when it is a potential cause of the target, but not when it is a potential effect. Findings show a stark difference in performance between preschoolers and adults: While adults blocked the redundant cue only in the prediction condition, children blocked the redundant cue indiscriminately across both conditions. Therefore, children, but not adults ignored the causal structure of the events. These findings challenge a developmental account that attributes sophisticated machinery of causal reasoning to young children. PMID:24033577

  11. How Young Children Learn to Program with Sensor, Action, and Logic Blocks

    ERIC Educational Resources Information Center

    Wyeth, Peta

    2008-01-01

    Electronic Blocks are a new programming environment designed specifically for children aged between 3 and 8 years. These physical, stackable blocks include sensor blocks, action blocks, and logic blocks. By connecting these blocks, children can program a wide variety of structures that interact with one another and the environment. Electronic…

  12. Protograph based LDPC codes with minimum distance linearly growing with block size

    NASA Technical Reports Server (NTRS)

    Divsalar, Dariush; Jones, Christopher; Dolinar, Sam; Thorpe, Jeremy

    2005-01-01

    We propose several LDPC code constructions that simultaneously achieve good threshold and error floor performance. Minimum distance is shown to grow linearly with block size (similar to regular codes of variable degree at least 3) by considering ensemble average weight enumerators. Our constructions are based on projected graph, or protograph, structures that support high-speed decoder implementations. As with irregular ensembles, our constructions are sensitive to the proportion of degree-2 variable nodes. A code with too few such nodes tends to have an iterative decoding threshold that is far from the capacity threshold. A code with too many such nodes tends to not exhibit a minimum distance that grows linearly in block length. In this paper we also show that precoding can be used to lower the threshold of regular LDPC codes. The decoding thresholds of the proposed codes, which have linearly increasing minimum distance in block size, outperform that of regular LDPC codes. Furthermore, a family of low to high rate codes, with thresholds that adhere closely to their respective channel capacity thresholds, is presented. Simulation results for a few example codes show that the proposed codes have low error floors as well as good threshold SNFt performance.

  13. Crystallization-driven one-dimensional self-assembly of polyethylene-b-poly(tert-butylacrylate) diblock copolymers in DMF: effects of crystallization temperature and the corona-forming block.

    PubMed

    Fan, Bin; Liu, Lei; Li, Jun-Huan; Ke, Xi-Xian; Xu, Jun-Ting; Du, Bin-Yang; Fan, Zhi-Qiang

    2016-01-07

    Crystallization-driven self-assembly of polyethylene-b-poly(tert-butylacrylate) (PE-b-PtBA) block copolymers (BCPs) in N,N-dimethyl formamide (DMF) was studied. It is found that all three PE-b-PtBA BCPs used in this work can self-assemble into one-dimensional crystalline cylindrical micelles. When the BCP solution is cooled to crystallization temperature (Tc) from 130 °C, the seed micelles may be produced via two competitive processes in the initial period: stepwise micellization/crystallization and simultaneous crystallization/micellization. Subsequently, the seed micelles can undergo growth driven by the epitaxial crystallization of the unimers. The lengths of both the seed micelles and the grown micelles are longer for the BCP with a longer PtBA block at a higher Tc. Quasi-living growth of the PE-b-PtBA crystalline cylindrical micelles is achieved at a higher Tc. A longer PtBA block evidently retards the attachment of unimers to the crystalline micelles, leading to a slower growth rate.

  14. PIXE analysis of elements in gastric cancer and adjacent mucosa

    NASA Astrophysics Data System (ADS)

    Liu, Qixin; Zhong, Ming; Zhang, Xiaofeng; Yan, Lingnuo; Xu, Yongling; Ye, Simao

    1990-04-01

    The elemental regional distributions in 20 resected human stomach tissues were obtained using PIXE analysis. The samples were pathologically divided into four types: normal, adjacent mucosa A, adjacent mucosa B and cancer. The targets for PIXE analysis were prepared by wet digestion with a pressure bomb system. P, K, Fe, Cu, Zn and Se were measured and statistically analysed. We found significantly higher concentrations of P, K, Cu, Zn and a higher ratio of Cu compared to Zn in cancer tissue as compared with normal tissue, but statistically no significant difference between adjacent mucosa and cancer tissue was found.

  15. Downscaling ocean conditions with application to the Gulf of Maine, Scotian Shelf and adjacent deep ocean

    NASA Astrophysics Data System (ADS)

    Katavouta, Anna; Thompson, Keith

    2017-04-01

    A high resolution regional model (1/36 degree) of the Gulf of Maine, Scotian Shelf and adjacent deep ocean (GoMSS) is developed to downscale ocean conditions from an existing global operational system. First, predictions from the regional GoMSS model in a one-way nesting set up are evaluated using observations from multiple sources including satellite-borne sensors of surface temperature and sea level, CTDs, Argo floats and moored current meters. It is shown that on the shelf, the regional model predicts more realistic fields than the global system because it has higher resolution and includes tides that are absent from the global system. However, in deep water the regional model misplaces deep ocean eddies and meanders associated with the Gulf Stream. This is because of unrealistic internally generated variability (associated with the one-way nesting set up) that leads to decoupling of the regional model from the global system in the deep water. To overcome this problem, the large scales (length scales > 90 km) of the regional model are spectrally nudged towards the global system fields. This leads to more realistic predictions off the shelf. Wavenumber spectra show that even though spectral nudging constrains the large scales, it does not suppress the variability on small scales; on the contrary, it favours the formation of eddies with length scales below the cut-off wavelength of the spectral nudging.

  16. [Efficacy and safety of ultrasound-guided or neurostimulator-guided bilateral axillary brachial plexus block].

    PubMed

    Xu, C S; Zhao, X L; Zhou, H B; Qu, Z J; Yang, Q G; Wang, H J; Wang, G

    2017-10-17

    Objective: To explore the efficacy and safety of bilateral axillary brachial plexus block under the guidance of ultrasound or neurostimulator. Methods: From February 2012 to April 2014, 120 patients undergoing bilateral hand/forearm surgery in Beijing Jishuitan Hospital were enrolled and anaesthetized with bilateral axillary brachial plexus block. All patients were divided into two groups randomly using random number table: the ultrasound-guided group (group U, n =60) and the neurostimulator-guidedgroup (group N, n =60). The block was performed with 0.5% ropivacaine. Patients' age, sex and operation duration were recorded. Moreover, success rate, performance time, onset of sensor and motor block, performance pain, patient satisfaction degree and the incidence of related complications were also documented. Venous samples were collected at selected time points and the total and the plasma concentrations of ropivacaine were analyzed with HPLC. Results: The performance time, the onset of sensor block and the onset of motor block of group U were (8.2±1.5), (14.2± 2.2)and (24.0±3.5)min respectively, which were markedly shorter than those in group N( (14.6±3.9), (19.9±3.8), (28.8±4.2)min, respectively), and the differences were statistically significant( t =11.74, 10.09, 6.73, respectively, all P <0.01). The performance pain score of group N was (25.5± 13.2), which was obviously more serious than group U (31.7± 11.2) and a significant statistical difference was detected ( t =2.856, P <0.05). The patient satisfaction degree of group U was 95.0%, which was significantly higher than group N (83.3%) and a markedly statistical difference was detected (χ(2)=4.227, P <0.05). Fifty min after performance, the total plasma concentration of ropivacaine of group U was(1.76±0.48)mg/L, which was significantly lower than group N (1.88±0.53)mg/L and a significant statistical difference was detected ( t =2.43, P <0.05), while no significant differences were detected at the

  17. Analysis of the width-w non-adjacent form in conjunction with hyperelliptic curve cryptography and with lattices☆

    PubMed Central

    Krenn, Daniel

    2013-01-01

    In this work the number of occurrences of a fixed non-zero digit in the width-w non-adjacent forms of all elements of a lattice in some region (e.g. a ball) is analysed. As bases, expanding endomorphisms with eigenvalues of the same absolute value are allowed. Applications of the main result are on numeral systems with an algebraic integer as base. Those come from efficient scalar multiplication methods (Frobenius-and-add methods) in hyperelliptic curves cryptography, and the result is needed for analysing the running time of such algorithms. The counting result itself is an asymptotic formula, where its main term coincides with the full block length analysis. In its second order term a periodic fluctuation is exhibited. The proof follows Delange’s method. PMID:23805020

  18. Tookad-mediated photodynamic effects on the prostate and its adjacent tissues: in vivo study in canine models

    NASA Astrophysics Data System (ADS)

    Huang, Zheng; Chen, Qun; Luck, David; Beckers, Jill; Blanc, Dominique; Hetzel, Fred W.

    2005-04-01

    Photodynamic therapy (PDT) mediated with a vascular acting photosensitizer Tookad (pd-bacteriopheophorbide), was investigated as an alternative treatment modality for prostate cancer. Tookad photodynamic effects on the prostate and its adjacent tissues were evaluated in canine models. Interstitial prostate PDT was performed by irradiating individual lobes with a diode laser (763 nm) and 1-cm cylindrical diffuser fibers at various light doses to activate the IV administered photosensitizer Tookad (1 - 2 mg/kg). The sensitivity of the adjacent tissues to Tookad-PDT was determined by superficially irradiating the surfaces of the bladder, colon, abdominal muscle and pelvic plexus with a microlens fiber at various drug/light doses. PDT effect on the prostatic urethra was evaluated by transurethral irradiation. The prostate and adjacent tissues were harvested one-week after the treatment and subjected to histopathologic examination. At one-week post interstitial prostate PDT, the animals recovered well with little or no urethral complications. PDT induced prostate lesions were characterized by marked hemorrhagic necrosis. The bladder, colon, abdominal muscle and pelvic plexus, appeared to also be sensitive to Tookad-PDT at light dose levels greater than 40 Jcm2. Urethral mucosa appeared less sensitive to Tookad-PDT. In conclusion, Tookad-mediated PDT demonstrates very strong vascular effects and can provide an effective alternative for the treatment of localized prostate cancer. Protection of the adjacent tissues should be taken into consideration in the total prostate ablation process due to their sensitivity to the Tookad-mediated PDT.

  19. Map showing distribution of gold in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, W.R.; Motooka, J.M.; McHugh, J.B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of gold in the less-than-0.180-mm (minus-80-mesh) fraction of stream sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the Selected References of this report. The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  20. Map showing distribution of thorium in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of thorium in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  1. Map showing distribution of zinc in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of zinc in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  2. Map showing distribution of copper in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle shows the regional distribution of copper in the less-than-0.180-mm (minus-80-mesh) fraction of stream sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  3. Map showing distribution of barium in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle shows the regional distribution of barium in the less-than-0.180-mm (minus-80-mesh) fraction of stream sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  4. Map showing distribution of lead in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of lead in the less-than-0.180-mm (minus-80-mesh) fraction of stream sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  5. Map showing distribution of molybdenum in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of molybdenum in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  6. Map showing distribution of silver in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of silver in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  7. Map showing distribution of tin in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of tin in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  8. Map showing distribution of uranium in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of uranium in the less-than-0.180-mm (minus-80-mesh) fraction of stream-sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  9. Local entanglement entropy of fermions as a marker of quantum phase transition in the one-dimensional Hubbard model

    NASA Astrophysics Data System (ADS)

    Cha, Min-Chul; Chung, Myung-Hoon

    2018-05-01

    We study quantum phase transition of interacting fermions by measuring the local entanglement entropy in the one-dimensional Hubbard model. The reduced density matrices for blocks of a few sites are constructed from the ground state wave function in infinite systems by adopting the matrix product state representation where time-evolving block decimations are performed to obtain the lowest energy states. The local entanglement entropy, constructed from the reduced density matrices, as a function of the chemical potential shows clear signatures of the Mott transition. The value of the central charge, numerically determined from the universal properties of the local entanglement entropy, confirms that the transition is caused by the suppression of the charge degrees of freedom.

  10. Microwave treatment of renal cell carcinoma adjacent to renal sinus.

    PubMed

    Gao, Yongyan; Liang, Ping; Yu, Xiaoling; Yu, Jie; Cheng, Zhigang; Han, Zhiyu; Duan, Shaobo; Huang, Hui

    2016-11-01

    To evaluate the efficacy and safety of ultrasound (US)-guided percutaneous microwave ablation (MWA) for renal cell carcinoma (RCC) adjacent to renal sinus. This retrospective study included 41 patients who underwent US-guided percutaneous MWA of 41 RCCs adjacent to the renal sinus from April 2006 to December 2015. Contrast-enhanced images of US and computed tomography (CT) or magnetic resonance (MR) imaging were performed at pre-ablation and 1day, 1 month, 3 months, and every 6 months after ablation. Initial ablation success (IAS), disease-free survival (DFS), RCC-related survival (RRS), and overall survival (OS) were recorded at the follow-up visits. IAS was achieved in 92.7% (38/41) of the study subjects. The IAS significantly differed between patients with RCCs ≤4cm (100%, 29/29) and RCCs >4cm (75%, 9/12, p=0.021). During the median follow-up of 37.6 (range, 3.0-97.3) months, the estimated 1-, 3-, and 5-year DFS of patients with an initial tumor of ≤4cm were 100%, 89.7%, and 81.5%, respectively. The 1-, 3-, and 5-year RRS were 100%, 93.3%, and 93.3%, respectively. The 1-, 3-, and 5-year OS were 97.1%, 87.8%, and 83.6%, respectively. The multivariate analysis using the Cox proportional hazard model revealed no independent predictor of recurrence among all the variables. There were no MWA-related deaths among the study subjects. One patient developed a retroperitoneal abscess after ablation. US-guided percutaneous MWA appears to be a promising method for RCCs adjacent to renal sinus, especially for tumors ≤4cm. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Toothbrushing alters the surface roughness and gloss of composite resin CAD/CAM blocks.

    PubMed

    Kamonkhantikul, Krid; Arksornnukit, Mansuang; Lauvahutanon, Sasipin; Takahashi, Hidekazu

    2016-01-01

    This study investigated the surface roughness and gloss of composite resin CAD/CAM blocks after toothbrushing. Five composite resin blocks (Block HC, Cerasmart, Gradia Block, KZR-CAD Hybrid Resin Block, and Lava Ultimate), one hybrid ceramic (Vita Enamic), one feldspar ceramic (Vitablocs Mark II), one PMMA block (Telio CAD), and one conventional composite resin (Filtek Z350 XT) were evaluated. Surface roughness (Ra) and gloss were determined for each group of materials (n=6) after silicon carbide paper (P4000) grinding, 10k, 20k, and 40k toothbrushing cycles. One-way repeated measures ANOVA indicated significant differences in the Ra and gloss of each material except for the Ra of GRA. After 40k toothbrushing cycles, the Ra of BLO and TEL showed significant increases, while CER, KZR, ULT, and Z350 showed significant decreases. GRA, ENA, and VIT maintained their Ra. All of the materials tested, except CER, demonstrated significant decreases in gloss after 40k toothbrushing cycles.

  12. Adjacent-level arthroplasty following cervical fusion.

    PubMed

    Rajakumar, Deshpande V; Hari, Akshay; Krishna, Murali; Konar, Subhas; Sharma, Ankit

    2017-02-01

    OBJECTIVE Adjacent-level disc degeneration following cervical fusion has been well reported. This condition poses a major treatment dilemma when it becomes symptomatic. The potential application of cervical arthroplasty to preserve motion in the affected segment is not well documented, with few studies in the literature. The authors present their initial experience of analyzing clinical and radiological results in such patients who were treated with arthroplasty for new or persistent arm and/or neck symptoms related to neural compression due to adjacent-segment disease after anterior cervical discectomy and fusion (ACDF). METHODS During a 5-year period, 11 patients who had undergone ACDF anterior cervical discectomy and fusion (ACDF) and subsequently developed recurrent neck or arm pain related to adjacent-level cervical disc disease were treated with cervical arthroplasty at the authors' institution. A total of 15 devices were implanted (range of treated levels per patient: 1-3). Clinical evaluation was performed both before and after surgery, using a visual analog scale (VAS) for pain and the Neck Disability Index (NDI). Radiological outcomes were analyzed using pre- and postoperative flexion/extension lateral radiographs measuring Cobb angle (overall C2-7 sagittal alignment), functional spinal unit (FSU) angle, and range of motion (ROM). RESULTS There were no major perioperative complications or device-related failures. Statistically significant results, obtained in all cases, were reflected by an improvement in VAS scores for neck/arm pain and NDI scores for neck pain. Radiologically, statistically significant increases in the overall lordosis (as measured by Cobb angle) and ROM at the treated disc level were observed. Three patients were lost to follow-up within the first year after arthroplasty. In the remaining 8 cases, the duration of follow-up ranged from 1 to 3 years. None of these 8 patients required surgery for the same vertebral level during the follow

  13. Organic photosensitive optoelectronic device having a phenanthroline exciton blocking layer

    DOEpatents

    Thompson, Mark E [Anaheim Hills, CA; Li, Jian [Los Angeles, CA; Forrest, Stephen [Princeton, NJ; Rand, Barry [Princeton, NJ

    2011-02-22

    An organic photosensitive optoelectronic device, having an anode, a cathode, and an organic blocking layer between the anode and the cathode is described, wherein the blocking layer comprises a phenanthroline derivative, and at least partially blocks at least one of excitons, electrons, and holes.

  14. Occurrence and surgical repair of third degree perineal lacerations in adult female camels (Camelus dromedarius) by one-stage (Goetz) technique

    PubMed Central

    Anwar, S.; Purohit, G.N.

    2013-01-01

    Retrospective analysis of third degree perineal lacerations in 7 female camels (6-17 yrs of age) that were surgically corrected by one stage repair (Goetz technique) is presented. Majority (3/7) of the camels was primiparous and all parturitions had a history of calving assistance. Six (6/7) camels recovered by first intention of healing. Dehiscence of perineal structure occurred in only one camel due to infection and healed by second intention. Subsequent matings resulted in pregnancy in four camels and one camel died due to unrelated causes. We conclude that perineal lacerations can occur in primiparous camels with difficult assisted deliveries and that one stage repair of perineal lacerations in camels improves the perineal conformation and such camels may easily regain normal fertility. PMID:26623316

  15. Variable-energy collimator for high-energy radiation

    DOEpatents

    Hill, R.A.

    1982-03-03

    An apparatus is disclosed providing a variable aperture energy beam collimator. A plurality of beam opaque blocks are in sliding interface edge contact to form a variable aperture. The blocks may be offset at the apex angle to provide a non-equilateral aperture. A plurality of collimator block assemblies may be employed for providing a channel defining a collimated beam. Adjacent assemblies are inverted front-to-back with respect to one another for preventing noncollimated ;energy from emergine from the apparatus. An adjustment mechanism comprises a cable attached to at least one block and a hand wheel mechanism for operating the cable. The blocks are supported by guide rods engaging slide brackets on the blocks. The guide rods are pivotally connected at each end to intermediate actuators supported on rotatable shafts to change the shape of the aperture. A divergent collimated beam may be obtained by adjusting the apertures of adjacent stages to be unequal.

  16. Variable aperture collimator for high energy radiation

    DOEpatents

    Hill, Ronald A.

    1984-05-22

    An apparatus is disclosed providing a variable aperture energy beam collimator. A plurality of beam opaque blocks are in sliding interface edge contact to form a variable aperture. The blocks may be offset at the apex angle to provide a non-equilateral aperture. A plurality of collimator block assemblies may be employed for providing a channel defining a collimated beam. Adjacent assemblies are inverted front-to-back with respect to one another for preventing noncollimated energy from emerging from the apparatus. An adjustment mechanism comprises a cable attached to at least one block and a hand wheel mechanism for operating the cable. The blocks are supported by guide rods engaging slide brackets on the blocks. The guide rods are pivotally connected at each end to intermediate actuators supported on rotatable shafts to change the shape of the aperture. A divergent collimated beam may be obtained by adjusting the apertures of adjacent stages to be unequal.

  17. 49 CFR 214.107 - Working over or adjacent to water.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Working over or adjacent to water. 214.107 Section 214.107 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD WORKPLACE SAFETY Bridge Worker Safety Standards § 214.107 Working over or adjacent to water. (a)...

  18. 49 CFR 214.107 - Working over or adjacent to water.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Working over or adjacent to water. 214.107 Section 214.107 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD WORKPLACE SAFETY Bridge Worker Safety Standards § 214.107 Working over or adjacent to water. (a)...

  19. 49 CFR 214.107 - Working over or adjacent to water.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Working over or adjacent to water. 214.107 Section 214.107 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD WORKPLACE SAFETY Bridge Worker Safety Standards § 214.107 Working over or adjacent to water. (a)...

  20. Epidural block

    MedlinePlus

    ... body. This lessens the pain of contractions during childbirth. An epidural block may also be used to ... extremities. This article focuses on epidural blocks during childbirth. How is the Epidural Given? The block or ...

  1. Nonuniformity correction for an infrared focal plane array based on diamond search block matching.

    PubMed

    Sheng-Hui, Rong; Hui-Xin, Zhou; Han-Lin, Qin; Rui, Lai; Kun, Qian

    2016-05-01

    In scene-based nonuniformity correction algorithms, artificial ghosting and image blurring degrade the correction quality severely. In this paper, an improved algorithm based on the diamond search block matching algorithm and the adaptive learning rate is proposed. First, accurate transform pairs between two adjacent frames are estimated by the diamond search block matching algorithm. Then, based on the error between the corresponding transform pairs, the gradient descent algorithm is applied to update correction parameters. During the process of gradient descent, the local standard deviation and a threshold are utilized to control the learning rate to avoid the accumulation of matching error. Finally, the nonuniformity correction would be realized by a linear model with updated correction parameters. The performance of the proposed algorithm is thoroughly studied with four real infrared image sequences. Experimental results indicate that the proposed algorithm can reduce the nonuniformity with less ghosting artifacts in moving areas and can also overcome the problem of image blurring in static areas.

  2. 77 FR 43658 - Designation of One (1) Entity Pursuant to Executive Order 13572 of April 29, 2011, “Blocking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... Human Rights Abuses in Syria'' AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice... of April 29, 2011, ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in... Executive Order 13572, ``Blocking Property of Certain Persons with Respect to Human Rights Abuses in Syria...

  3. 78 FR 31630 - Designation of One (1) Entity Pursuant to Executive Order 13582 of August 17, 2011, “Blocking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... to Executive Order 13582 of August 17, 2011, ``Blocking Property of the Government of Syria and Prohibiting Certain Transactions With Respect to Syria'' AGENCY: Office of Foreign Assets Control, Treasury... Executive Order 13582 of August 17, 2011, ``Blocking Property of the Government of Syria and Prohibiting...

  4. 77 FR 49864 - Designation of One (1) Entity Pursuant to Executive Order 13582 of August 17, 2011, “Blocking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... to Executive Order 13582 of August 17, 2011, ``Blocking Property of the Government of Syria and Prohibiting Certain Transactions With Respect to Syria'' AGENCY: Office of Foreign Assets Control, Treasury... Executive Order 13582 of August 17, 2011, ``Blocking Property of the Government of Syria and Prohibiting...

  5. A 3D Analysis of Rock Block Deformation and Failure Mechanics Using Terrestrial Laser Scanning

    NASA Astrophysics Data System (ADS)

    Rowe, Emily; Hutchinson, D. Jean; Kromer, Ryan A.; Edwards, Tom

    2017-04-01

    Many natural geological hazards are present along the Thompson River corridor in British Columbia, Canada, including one particularly hazardous rocky slope known as the White Canyon. Railway tracks used by Canadian National (CN) and Canadian Pacific (CP) Railway companies pass through this area at the base of the Canyon slope. The geologically complex and weathered rock face exposed at White Canyon is prone to rockfalls. With a limited ditch capacity, these falling rocks have the potential to land on the tracks and therefore increase the risk of train derailment. Since 2012, terrestrial laser scanning (TLS) data has been collected at this site on a regular basis to enable researchers at Queen's University to study these rockfalls in greater detail. In this paper, the authors present a summary of an analysis of these TLS datasets including an examination of the pre-failure deformation patterns exhibited by failed rock blocks as well as an investigation into the influence of structural constraints on the pre-failure behavior of these blocks. Aligning rockfall source zones in an early point cloud dataset to a later dataset generates a transformation matrix describing the movement of the block from one scan to the next. This process was repeated such that the motion of the block over the entire TLS data coverage period was measured. A 3D roto-translation algorithm was then used to resolve the motion into translation and rotation components (Oppikofer et al. 2009; Kromer et al. 2015). Structural information was plotted on a stereonet for further analysis. A total of 111 rockfall events exceeding a volume of 1 m3 were analyzed using this approach. The study reveals that although some rockfall source blocks blocks do not exhibit detectable levels of deformation prior to failure, others do experience cm-level translation and rotation on the order of 1 to 6 degrees before detaching from the slope. Moreover, these movements may, in some cases, be related to the discontinuity

  6. First Professional Degree Awards to Women.

    ERIC Educational Resources Information Center

    Brown, George H.

    Changes in the percentage representation of women among recipients of first professional degrees are examined between the academic years 1970-71 and 1975-76. The data were collected through the annual Survey of Degrees and Other Formal Awards Conferred. A first professional degree is one that "signifies completion of the academic requirements for…

  7. Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.

    PubMed

    Yun, M J; Kim, Y H; Han, M K; Kim, J H; Hwang, J W; Do, S H

    2009-11-01

    In this prospective randomized study, the authors compared the analgesic effect of a fascia iliaca compartment (FIC) block with that of intravenous (i.v.) alfentanil when administered to facilitate positioning for spinal anaesthesia in elderly patients undergoing surgery for a femoral neck fracture. The 40 patients were randomly assigned to one of two groups, namely, the FIC group (fascia iliaca compartment block, n=20) and the IVA group (intravenous analgesia with alfentanil, n=20). Group IVA patients received a bolus dose of i.v. alfentanil 10 microg/kg, followed by a continuous infusion of alfentanil 0.25 microg/kg/min starting 2 min before the spinal block, and group FIC patients received a FIC block with 30 ml of ropivacaine 3.75 mg/ml (112.5 mg) 20 min before the spinal block. Visual analogue pain scale (VAS) scores, time to achieve spinal anaesthesia, quality of patient positioning, and patient acceptance were compared. VAS scores during positioning (mean and range) were lower in the FIC group than in the IVA group [2.0 (1-4) vs. 3.5 (2-6), P=0.001], and the mean (+/- SD) time to achieve spinal anaesthesia was shorter in the FIC group (6.9 +/- 2.7 min vs. 10.8 +/- 5.6 min; P=0.009). Patient acceptance (yes/no) was also better in the FIC group (19/1) than in the IVA group (12/8)(P=0.008). An FIC block is more efficacious than i.v. alfentanil in terms of facilitating the lateral position for spinal anaesthesia in elderly patients undergoing surgery for femoral neck fractures.

  8. Impacted maxillary canines and root resorption of adjacent teeth: A retrospective observational study.

    PubMed

    Guarnieri, R; Cavallini, C; Vernucci, R; Vichi, M; Leonardi, R; Barbato, E

    2016-11-01

    The prevalence of impacted maxillary canine is reported to be between 1% and 3%. The lack of monitoring and the delay in the treatment of the impacted canine can cause different complications such as: displacement of adjacent teeth, loss of vitality of neighbouring teeth, shortening of the dental arch, follicular cysts, canine ankylosis, recurrent infections, recurrent pain, internal resorption of the canine and the adjacent teeth, external resorption of the canine and the adjacent teeth, combination of these factors. An appropriate diagnosis, accurate predictive analysis and early intervention are likely to prevent such undesirable effects. The objective is to evaluate, by means of a retrospective observational study, the possibility of carrying out a predictive analysis of root resorption adjacent to the impacted canines by means of orthopantomographs, so as to limit the prescription of additional 3D radiography. 120 subjects with unilateral or bilateral maxillary impacted canine were examined and 50 patients with 69 impacted maxillary canine (22 male, 28 female; mean age: 11.7 years) satisfied the inclusion criteria of the study. These patients were subjected to a basic clinical and radiographic investigation (orthopantomographs and computerized tomography). All panoramic films were viewed under standardized conditions for the evaluation of two main variables: maxillary canine angulations (a, b, g angles) and the overlapping between the impacted teeth and the lateral incisor (Analysis of Lindauer). Binary logistic regression was used to estimate the likelihood of resorbed lateral incisors depending on sector location and angle measurements. Results indicated that b angle has the greatest influence on the prediction of root resorption (predictive value of b angle = 76%). If β angle <18° and Lindauer = I, the probability of resorption is 0.06. Evaluation of b angle and superimposition lateral incisor/impacted canine analysed on orthopantomographs could be one of

  9. First-Principles Prediction of New Electrides with Nontrivial Band Topology Based on One-Dimensional Building Blocks

    NASA Astrophysics Data System (ADS)

    Park, Changwon; Kim, Sung Wng; Yoon, Mina

    2018-01-01

    We introduce a new class of electrides with nontrivial band topology by coupling materials database searches and first-principles-calculations-based analysis. Cs3O and Ba3N are for the first time identified as a new class of electrides, consisting of one-dimensional (1D) nanorod building blocks. Their crystal structures mimic β -TiCl3 with the position of anions and cations exchanged. Unlike the weakly coupled nanorods of β -TiCl3 , Cs3O and Ba3N retain 1D anionic electrons along the hollow interrod sites; additionally, a strong interrod interaction in C3O and Ba3N induces band inversion in a 2D superatomic triangular lattice, resulting in Dirac-node lines. The new class of electrides can serve as a prototype for new electrides with a large cavity space that can be utilized for various applications such as gas storage, ion transport, and metal intercalation.

  10. A One-Step Route to CO2 -Based Block Copolymers by Simultaneous ROCOP of CO2 /Epoxides and RAFT Polymerization of Vinyl Monomers.

    PubMed

    Wang, Yong; Zhao, Yajun; Ye, Yunsheng; Peng, Haiyan; Zhou, Xingping; Xie, Xiaolin; Wang, Xianhong; Wang, Fosong

    2018-03-26

    The one-step synthesis of well-defined CO 2 -based diblock copolymers was achieved by simultaneous ring-opening copolymerization (ROCOP) of CO 2 /epoxides and RAFT polymerization of vinyl monomers using a trithiocarbonate compound bearing a carboxylic group (TTC-COOH) as the bifunctional chain transfer agent (CTA). The double chain-transfer effect allows for independent and precise control over the molecular weight of the two blocks and ensures narrow polydispersities of the resultant block copolymers (1.09-1.14). Notably, an unusual axial group exchange reaction between the aluminum porphyrin catalyst and TTC-COOH impedes the formation of homopolycarbonates. By taking advantage of the RAFT technique, it is able to meet the stringent demand for functionality control to well expand the application scopes of CO 2 -based polycarbonates. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Building blocks for subleading helicity operators

    DOE PAGES

    Kolodrubetz, Daniel W.; Moult, Ian; Stewart, Iain W.

    2016-05-24

    On-shell helicity methods provide powerful tools for determining scattering amplitudes, which have a one-to-one correspondence with leading power helicity operators in the Soft-Collinear Effective Theory (SCET) away from singular regions of phase space. We show that helicity based operators are also useful for enumerating power suppressed SCET operators, which encode subleading amplitude information about singular limits. In particular, we present a complete set of scalar helicity building blocks that are valid for constructing operators at any order in the SCET power expansion. In conclusion, we also describe an interesting angular momentum selection rule that restricts how these building blocks canmore » be assembled.« less

  12. Additive Manufacturing of Molds for Fabrication of Insulated Concrete Block

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Love, Lonnie J.; Lloyd, Peter D.

    ORNL worked with concrete block manufacturer, NRG Insulated Block, to demonstrate additive manufacturing of a multi-component block mold for its line of insulated blocks. Solid models of the mold parts were constructed from existing two-dimensional drawings and the parts were fabricated on a Stratasys Fortus 900 using ULTEM 9085. Block mold parts were delivered to NRG and installed on one of their fabrication lines. While form and fit were acceptable, the molds failed to function during NRG’s testing.

  13. The Effectiveness of Articulation and Transfer Agreements between Missouri Community Colleges and Universities in Promoting the Successful Completion of a Four-Year Degree

    ERIC Educational Resources Information Center

    Perkins, Katherine S.

    2010-01-01

    American community colleges have become important in the pursuit of a four-year degree. The state of Missouri established an Associates of Arts degree and the 42-hour general education block option to assist students with transfer and degree completion in the shortest time possible (Coordinating Board for Higher Education, 2000). If articulation…

  14. Teaching strategies and student achievement in high school block scheduled biology classes

    NASA Astrophysics Data System (ADS)

    Louden, Cynthia Knapp

    The objectives of this study included determining whether teachers in block or traditionally scheduled biology classes (1) implement inquiry-based instruction more often or with different methods, (2) understand the concept of inquiry-based instruction as it is described in the National Science Standards, (3) have classes with significantly different student achievement, and (4) believe that their school schedule facilitates their use of inquiry-based instruction in the classroom. Biology teachers in block and non-block scheduled classes were interviewed, surveyed, and observed to determine the degree to which they implement inquiry-based instructional practices in their classrooms. State biology exams were used to indicate student achievement. Teachers in block scheduled and traditional classes used inquiry-based instruction with nearly the same frequency. Approximately 30% of all teachers do not understand the concept of inquiry-based instruction as described by the National Science Standards. No significant achievement differences between block and traditionally scheduled biology classes were found using ANCOVA analyses and a nonequivalent control-group quasi-experimental design. Using the same analysis techniques, significant achievement differences were found between biology classes with teachers who used inquiry-based instruction frequently and infrequently. Teachers in block schedules believed that their schedules facilitated inquiry-based instruction more than teachers in traditional schedules.

  15. A Comparison of Jump Height, Takeoff Velocities, and Blocking Coverage in the Swing and Traditional Volleyball Blocking Techniques

    PubMed Central

    Ficklin, Travis; Lund, Robin; Schipper, Megan

    2014-01-01

    The purpose of this study was to compare traditional and swing blocking techniques on center of mass (COM) projectile motion and effective blocking area in nine healthy Division I female volleyball players. Two high-definition (1080 p) video cameras (60 Hz) were used to collect two-dimensional variables from two separate views. One was placed perpendicular to the plane of the net and the other was directed along the top of the net, and were used to estimate COM locations and blocking area in a plane parallel to the net and hand penetration through the plane of the net respectively. Video of both the traditional and swing techniques were digitized and kinematic variables were calculated. Paired samples t-tests indicated that the swing technique resulted in greater (p < 0.05) vertical and horizontal takeoff velocities (vy and vx), jump height (H), duration of the block (tBLOCK), blocking coverage during the block (C) as well as hand penetration above and through the net’s plane (YPEN, ZPEN). The traditional technique had significantly greater approach time (tAPP). The results of this study suggest that the swing technique results in both greater jump height and effective blocking area. However, the shorter tAPP that occurs with swing is associated with longer times in the air during the block which may reduce the ability of the athlete to make adjustments to attacks designed to misdirect the defense. Key Points Swing blocking technique has greater jump height, effective blocking area, hand penetration, horizontal and vertical takeoff velocity, and has a shorter time of approach. Despite these advantages, there may be more potential for mistiming blocks and having erratic deflections of the ball after contact when using the swing technique. Coaches should take more than simple jump height and hand penetration into account when deciding which technique to employ. PMID:24570609

  16. A comparison of jump height, takeoff velocities, and blocking coverage in the swing and traditional volleyball blocking techniques.

    PubMed

    Ficklin, Travis; Lund, Robin; Schipper, Megan

    2014-01-01

    The purpose of this study was to compare traditional and swing blocking techniques on center of mass (COM) projectile motion and effective blocking area in nine healthy Division I female volleyball players. Two high-definition (1080 p) video cameras (60 Hz) were used to collect two-dimensional variables from two separate views. One was placed perpendicular to the plane of the net and the other was directed along the top of the net, and were used to estimate COM locations and blocking area in a plane parallel to the net and hand penetration through the plane of the net respectively. Video of both the traditional and swing techniques were digitized and kinematic variables were calculated. Paired samples t-tests indicated that the swing technique resulted in greater (p < 0.05) vertical and horizontal takeoff velocities (vy and vx), jump height (H), duration of the block (tBLOCK), blocking coverage during the block (C) as well as hand penetration above and through the net's plane (YPEN, ZPEN). The traditional technique had significantly greater approach time (tAPP). The results of this study suggest that the swing technique results in both greater jump height and effective blocking area. However, the shorter tAPP that occurs with swing is associated with longer times in the air during the block which may reduce the ability of the athlete to make adjustments to attacks designed to misdirect the defense. Key PointsSwing blocking technique has greater jump height, effective blocking area, hand penetration, horizontal and vertical takeoff velocity, and has a shorter time of approach.Despite these advantages, there may be more potential for mistiming blocks and having erratic deflections of the ball after contact when using the swing technique.Coaches should take more than simple jump height and hand penetration into account when deciding which technique to employ.

  17. Early Verb Constructions in French: Adjacency on the Left Edge

    ERIC Educational Resources Information Center

    Veneziano, Edy; Clark, Eve V.

    2016-01-01

    Children acquiring French elaborate their early verb constructions by adding adjacent morphemes incrementally at the left edge of core verbs. This hypothesis was tested with 2657 verb uses from four children between 1;3 and 2;7. Consistent with the Adjacency Hypothesis, children added clitic subjects frst only to present tense forms (as in…

  18. Light-emitting block copolymers composition, process and use

    DOEpatents

    Ferraris, John P.; Gutierrez, Jose J.

    2006-11-14

    Generally, and in one form, the present invention is a composition of light-emitting block copolymer. In another form, the present invention is a process producing a light-emitting block copolymers that intends polymerizing a first di(halo-methyl) aromatic monomer compound in the presence of an anionic initiator and a base to form a polymer and contacting a second di(halo-methyl) aromatic monomer compound with the polymer to form a homopolymer or block copolymer wherein the block copolymer is a diblock, triblock, or star polymer. In yet another form, the present invention is an electroluminescent device comprising a light-emitting block copolymer, wherein the electroluminescent device is to be used in the manufacturing of optical and electrical devices.

  19. Adjacent bin stability evaluating for feature description

    NASA Astrophysics Data System (ADS)

    Nie, Dongdong; Ma, Qinyong

    2018-04-01

    Recent study improves descriptor performance by accumulating stability votes for all scale pairs to compose the local descriptor. We argue that the stability of a bin depends on the differences across adjacent pairs more than the differences across all scale pairs, and a new local descriptor is composed based on the hypothesis. A series of SIFT descriptors are extracted from multiple scales firstly. Then the difference value of the bin across adjacent scales is calculated, and the stability value of a bin is calculated based on it and accumulated to compose the final descriptor. The performance of the proposed method is evaluated with two popular matching datasets, and compared with other state-of-the-art works. Experimental results show that the proposed method performs satisfactorily.

  20. Vector wind, horizontal divergence, wind stress and wind stress curl from SEASAT-SASS at one degree resolution

    NASA Technical Reports Server (NTRS)

    Pierson, W. J., Jr.; Sylvester, W. B.; Salfi, R. E.

    1984-01-01

    Conventional data obtained in 1983 are contrasted with SEASAT-A scatterometer and scanning multichannel microwave radiometer (SMMR) data to show how observations at a single station can be extended to an area of about 150,000 square km by means of remotely sensed data obtained in nine minutes. Superobservations at a one degree resolution for the vector winds were estimated along with their standard deviations. From these superobservations, the horizontal divergence, vector wind stress, and the curl of the wind stress can be found. Weather forecasting theory is discussed and meteorological charts of the North Pacific Ocean are presented. Synoptic meteorology as a technique is examined.

  1. Active angular alignment of gauge blocks in double-ended interferometers.

    PubMed

    Buchta, Zdeněk; Reřucha, Simon; Hucl, Václav; Cížek, Martin; Sarbort, Martin; Lazar, Josef; Cíp, Ondřej

    2013-09-27

    This paper presents a method implemented in a system for automatic contactless calibration of gauge blocks designed at ISI ASCR. The system combines low-coherence interferometry and laser interferometry, where the first identifies the gauge block sides position and the second one measures the gauge block length itself. A crucial part of the system is the algorithm for gauge block alignment to the measuring beam which is able to compensate the gauge block lateral and longitudinal tilt up to 0.141 mrad. The algorithm is also important for the gauge block position monitoring during its length measurement.

  2. Active Angular Alignment of Gauge Blocks in Double-Ended Interferometers

    PubMed Central

    Buchta, Zdeněk; Řeřucha, Šimon; Hucl, Václav; Čížek, Martin; Šarbort, Martin; Lazar, Josef; Číp, Ondřej

    2013-01-01

    This paper presents a method implemented in a system for automatic contactless calibration of gauge blocks designed at ISI ASCR. The system combines low-coherence interferometry and laser interferometry, where the first identifies the gauge block sides position and the second one measures the gauge block length itself. A crucial part of the system is the algorithm for gauge block alignment to the measuring beam which is able to compensate the gauge block lateral and longitudinal tilt up to 0.141 mrad. The algorithm is also important for the gauge block position monitoring during its length measurement. PMID:24084107

  3. Novel Self-Assembling Amino Acid-Derived Block Copolymer with Changeable Polymer Backbone Structure.

    PubMed

    Koga, Tomoyuki; Aso, Eri; Higashi, Nobuyuki

    2016-11-29

    Block copolymers have attracted much attention as potentially interesting building blocks for the development of novel nanostructured materials in recent years. Herein, we report a new type of self-assembling block copolymer with changeable polymer backbone structure, poly(Fmoc-Ser) ester -b-PSt, which was synthesized by combining the polycondensation of 9-fluorenylmethoxycarbonyl-serine (Fmoc-Ser) with the reversible addition-fragmentation chain transfer (RAFT) polymerization of styrene (St). This block copolymer showed the direct conversion of the backbone structure from polyester to polypeptide through a multi O,N-acyl migration triggered by base-induced deprotection of Fmoc groups in organic solvent. Such polymer-to-polymer conversion was found to occur quantitatively without decrease in degree of polymerization and to cause a drastic change in self-assembling property of the block copolymer. On the basis of several morphological analyses using FTIR spectroscopy, atomic force, and transmission and scanning electron microscopies, the resulting peptide block copolymer was found to self-assemble into a vesicle-like hollow nanosphere with relatively uniform diameter of ca. 300 nm in toluene. In this case, the peptide block generated from polyester formed β-sheet structure, indicating the self-assembly via peptide-guided route. We believe the findings presented in this study offer a new concept for the development of self-assembling block copolymer system.

  4. Surface geology of the northern Midway-Sunset Field and adjacent Temblor Range, Kern County, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wylie, A.S. Jr.; Sturm, D.H.; Gardiner, R.L.

    1996-01-01

    New surface mapping at a 1:12000 scale adjacent to the 2 billion barrel Midway Sunset Field has revealed complex intraformational stratigraphy within the upper Miocene Santa Margarita Formation (Tms). Locally known as the Potter and Spellacy Formations in the subsurface, these sandstone and conglomerate heavy oil reservoirs produce the majority of Midway Sunset daily production of 164,000 barrels of oil via thermal EOR processes. The Tms consists mostly of conglomerate inserted into the Belridge Diatomite (Tmb) interval. The stratigraphically lower intervals of the Tms clearly fill deeply incised valleys or submarine canyons cut into Tmb and locally into the underlyingmore » Antelope Shale (Tma). The basal intervals of Tms; are very coarse grained, containing boulders of granitic and metamorphic rock as large as 4 meters that were derived from the Salinian block west of the San Andreas Fault. The upper intervals of Tms are more sheet-like and interbedded containing clasts less than 50 cm in length. The incised valleys have a spacing of about one mile in outcrop, with a gap located in the area of the older Republic Sandstone (Tmr). Paleocurrents from Tms regionally suggest sediment transport to the northeast. The sedimentary structures of Tms suggest deposition in deep-water conditions, probably a slope (bathyal) setting. Shelf environments should have been present to the southwest (now stripped away by erosion) and submarine-fan and basin-floor environments to the northeast.« less

  5. Surface geology of the northern Midway-Sunset Field and adjacent Temblor Range, Kern County, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wylie, A.S. Jr.; Sturm, D.H.; Gardiner, R.L.

    1996-12-31

    New surface mapping at a 1:12000 scale adjacent to the 2 billion barrel Midway Sunset Field has revealed complex intraformational stratigraphy within the upper Miocene Santa Margarita Formation (Tms). Locally known as the Potter and Spellacy Formations in the subsurface, these sandstone and conglomerate heavy oil reservoirs produce the majority of Midway Sunset daily production of 164,000 barrels of oil via thermal EOR processes. The Tms consists mostly of conglomerate inserted into the Belridge Diatomite (Tmb) interval. The stratigraphically lower intervals of the Tms clearly fill deeply incised valleys or submarine canyons cut into Tmb and locally into the underlyingmore » Antelope Shale (Tma). The basal intervals of Tms; are very coarse grained, containing boulders of granitic and metamorphic rock as large as 4 meters that were derived from the Salinian block west of the San Andreas Fault. The upper intervals of Tms are more sheet-like and interbedded containing clasts less than 50 cm in length. The incised valleys have a spacing of about one mile in outcrop, with a gap located in the area of the older Republic Sandstone (Tmr). Paleocurrents from Tms regionally suggest sediment transport to the northeast. The sedimentary structures of Tms suggest deposition in deep-water conditions, probably a slope (bathyal) setting. Shelf environments should have been present to the southwest (now stripped away by erosion) and submarine-fan and basin-floor environments to the northeast.« less

  6. Method for closing a drift between adjacent in situ oil shale retorts

    DOEpatents

    Hines, Alex E.

    1984-01-01

    A row of horizontally spaced-apart in situ oil shale retorts is formed in a subterranean formation containing oil shale. Each row of retorts is formed by excavating development drifts at different elevations through opposite side boundaries of a plurality of retorts in the row of retorts. Each retort is formed by explosively expanding formation toward one or more voids within the boundaries of the retort site to form a fragmented permeable mass of formation particles containing oil shale in each retort. Following formation of each retort, the retort development drifts on the advancing side of the retort are closed off by covering formation particles within the development drift with a layer of crushed oil shale particles having a particle size smaller than the average particle size of oil shale particles in the adjacent retort. In one embodiment, the crushed oil shale particles are pneumatically loaded into the development drift to pack the particles tightly all the way to the top of the drift and throughout the entire cross section of the drift. The closure between adjacent retorts provided by the finely divided oil shale provides sufficient resistance to gas flow through the development drift to effectively inhibit gas flow through the drift during subsequent retorting operations.

  7. How to push a block along a wall

    NASA Technical Reports Server (NTRS)

    Mason, Matthew T.

    1989-01-01

    Some robot tasks require manipulation of objects that may be touching other fixed objects. The effects of friction and kinematic constraint must be anticipated, and may even be exploited to accomplish the task. An example task, a dynamic analysis, and appropriate effector motions are presented. The goal is to move a rectangular block along a wall, so that one side of the block maintains contact with the wall. Two solutions that push the block along the wall are discussed.

  8. From global to heavy-light: 5-point conformal blocks

    NASA Astrophysics Data System (ADS)

    Alkalaev, Konstantin; Belavin, Vladimir

    2016-03-01

    We consider Virasoro conformal blocks in the large central charge limit. There are different regimes depending on the behavior of the conformal dimensions. The most simple regime is reduced to the global sl(2,C) conformal blocks while the most complicated one is known as the classical conformal blocks. Recently, Fitzpatrick, Kaplan, and Walters showed that the two regimes are related through the intermediate stage of the so-called heavy-light semiclassical limit. We study this idea in the particular case of the 5-point conformal block. To find the 5-point global block we use the projector technique and the Casimir operator approach. Furthermore, we discuss the relation between the global and the heavy-light limits and construct the heavy-light block from the global block. In this way we reproduce our previous results for the 5-point perturbative classical block obtained by means of the monodromy method.

  9. 77 FR 53164 - Railroad Workplace Safety; Adjacent-Track On-Track Safety for Roadway Workers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ...-0059, Notice No. 6] RIN 2130-AC37 Railroad Workplace Safety; Adjacent-Track On-Track Safety for Roadway... complex issues raised in both the petitions for reconsideration of the final rule published November 30... issues. One of the Petitions included a request for a delay in the effective date of the final rule until...

  10. Computational analysis of electrokinetically driven flow mixing in microchannels with patterned blocks

    NASA Astrophysics Data System (ADS)

    Chang, C.-C.; Yang, R.-J.

    2004-04-01

    Electroosmotic flow in microchannels is restricted to low Reynolds number regimes characterized by extremely weak inertia forces and laminar flow. Consequently, the mixing of different species occurs primarily through diffusion, and hence cannot readily be achieved within a short mixing channel. The current study presents a numerical investigation of electrokinetically driven flow mixing in microchannels with various numbers of incorporated patterned rectangular blocks. Furthermore, a novel approach is introduced which patterns heterogeneous surfaces on the upper faces of these rectangular blocks in order to enhance species mixing. The simulation results confirm that the introduction of rectangular blocks within the mixing channel slightly enhances species mixing by constricting the bulk flow, hence creating a stronger diffusion effect. However, it is noted that a large number of blocks and hence a long mixing channel are required if a complete mixing of the species is to be obtained. The results also indicate that patterning heterogeneous upper surfaces on the rectangular blocks is an effective means of enhancing the species mixing. It is shown that increasing the magnitude of the heterogeneous surface zeta potential enables a reduction in the mixing channel length and an improved degree of mixing efficiency.

  11. Objectifying the Adjacent and Opposite Angles: A Cultural Historical Analysis

    ERIC Educational Resources Information Center

    Daher, Wajeeh; Musallam, Nadera

    2018-01-01

    The angle topic is central to the development of geometric knowledge. Two of the basic concepts associated with this topic are the adjacent and opposite angles. It is the goal of the present study to analyze, based on the cultural historical semiotics framework, how high-achieving seventh grade students objectify the adjacent and opposite angles'…

  12. The categorisation of swimming start performance with reference to force generation on the main block and footrest components of the Omega OSB11 start blocks.

    PubMed

    Slawson, Sian E; Conway, Paul P; Cossor, Jodi; Chakravorti, Nandini; West, Andrew A

    2013-01-01

    Work presented in this paper provides a methodology for categorising swimming start performance based on peak force production on the main block and footrest components of the Omega OSB11 starting block. A total of 46 elite British swimmers were tested, producing over 1000 start trials. Overwater cameras were synchronised to a specifically designed start block that allowed the measurement of force production via two sets of four, tri-axis, force transducers; one set in the main block and one in the footrest. Data were then analysed, segregating trials for gender. Each start was categorised, with respect to the peak force production in horizontal and vertical components, into one of nine categories. Three performance indicators, i.e. block time, take-off velocity and distance of entry, were used to assess whether differences in performance could be correlated with these categories. Results from these data suggest that swimmers generating higher than average peak forces were more likely to produce a better overall start performance than those who produced forces lower than the average, for this population of athletes.

  13. Coarse mesh and one-cell block inversion based diffusion synthetic acceleration

    NASA Astrophysics Data System (ADS)

    Kim, Kang-Seog

    DSA (Diffusion Synthetic Acceleration) has been developed to accelerate the SN transport iteration. We have developed solution techniques for the diffusion equations of FLBLD (Fully Lumped Bilinear Discontinuous), SCB (Simple Comer Balance) and UCB (Upstream Corner Balance) modified 4-step DSA in x-y geometry. Our first multi-level method includes a block Gauss-Seidel iteration for the discontinuous diffusion equation, uses the continuous diffusion equation derived from the asymptotic analysis, and avoids void cell calculation. We implemented this multi-level procedure and performed model problem calculations. The results showed that the FLBLD, SCB and UCB modified 4-step DSA schemes with this multi-level technique are unconditionally stable and rapidly convergent. We suggested a simplified multi-level technique for FLBLD, SCB and UCB modified 4-step DSA. This new procedure does not include iterations on the diffusion calculation or the residual calculation. Fourier analysis results showed that this new procedure was as rapidly convergent as conventional modified 4-step DSA. We developed new DSA procedures coupled with 1-CI (Cell Block Inversion) transport which can be easily parallelized. We showed that 1-CI based DSA schemes preceded by SI (Source Iteration) are efficient and rapidly convergent for LD (Linear Discontinuous) and LLD (Lumped Linear Discontinuous) in slab geometry and for BLD (Bilinear Discontinuous) and FLBLD in x-y geometry. For 1-CI based DSA without SI in slab geometry, the results showed that this procedure is very efficient and effective for all cases. We also showed that 1-CI based DSA in x-y geometry was not effective for thin mesh spacings, but is effective and rapidly convergent for intermediate and thick mesh spacings. We demonstrated that the diffusion equation discretized on a coarse mesh could be employed to accelerate the transport equation. Our results showed that coarse mesh DSA is unconditionally stable and is as rapidly convergent

  14. Pathways to a Four-Year Degree: Determinants of Degree Completion among Socioeconomically Disadvantaged Students.

    ERIC Educational Resources Information Center

    Cabrera, Alberto F.; Burkum, Kurt R.; La Nasa, Steven M.

    The High School Sophomore Cohort of 1980 followed nine different pathways to a 4-year college degree. These paths were formed by a combination of different levels of academic preparation secured in high school and the first type of postsecondary institution attended. The pathway most likely to lead to a 4-year degree is one defined by acquiring…

  15. Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.

    PubMed

    Anderson, Matthew Z; Gerstein, Aleeza C; Wigen, Lauren; Baller, Joshua A; Berman, Judith

    2014-07-01

    Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites for gene amplification, which is thought to drive genetic diversity. Here we found that individual subtelomeric TLO genes exhibit increased variation in transcript and protein levels at both the cell-to-cell level as well as at the population-level. The cell-to-cell variation, termed Telomere-Adjacent Gene Expression Noise (TAGEN) was largely intrinsic noise and was dependent upon genome position: noise was reduced when a TLO gene was expressed at an ectopic internal locus and noise was elevated when a non-telomeric gene was expressed at a telomere-adjacent locus. This position-dependent TAGEN also was dependent on Sir2p, an NAD+-dependent histone deacetylase. Finally, we found that telomere silencing and TAGEN are tightly linked and regulated in cis: selection for either silencing or activation of a TLO-adjacent URA3 gene resulted in reduced noise at the neighboring TLO but not at other TLO genes. This provides experimental support to computational predictions that the ability to shift between silent and active chromatin states has a major effect on cell-to-cell noise. Furthermore, it demonstrates that these shifts affect the degree of expression variation at each telomere individually.

  16. The Volpe Center GPS Adjacent Band Compatibility Program Plan : GPS Adjacent Band Compatibility Workshop, Volpe Center, Cambridge MA

    DOT National Transportation Integrated Search

    2014-09-18

    Approach to DOT GPS Adjacent Band Compatibility Assessment. Identify forums and provide public outreach to make sure the progress and work are as open and transparent as possible. Develop an implementation plan that incorporates aspects from the DOT ...

  17. Automatic blocking of nested loops

    NASA Technical Reports Server (NTRS)

    Schreiber, Robert; Dongarra, Jack J.

    1990-01-01

    Blocked algorithms have much better properties of data locality and therefore can be much more efficient than ordinary algorithms when a memory hierarchy is involved. On the other hand, they are very difficult to write and to tune for particular machines. The reorganization is considered of nested loops through the use of known program transformations in order to create blocked algorithms automatically. The program transformations used are strip mining, loop interchange, and a variant of loop skewing in which invertible linear transformations (with integer coordinates) of the loop indices are allowed. Some problems are solved concerning the optimal application of these transformations. It is shown, in a very general setting, how to choose a nearly optimal set of transformed indices. It is then shown, in one particular but rather frequently occurring situation, how to choose an optimal set of block sizes.

  18. Use of an Android application "clinometer" for measurement of head down tilt given during subarachnoid block.

    PubMed

    Dixit, R B; Neema, M M

    2016-01-01

    Head down tilt is given to patients after sub arachnoid block for adjustment of height of block. However, the amount of tilt given is subjective and cannot be documented. We used an android application named "clinometer" to measure exact degree of tilt given by anesthesiologists as their routine practice. This observational study, at a medical college hospital, was done in 130 patients given sub arachnoid block for lower abdominal surgeries. We observed and documented vital data of patients and measured tilt given by application "clinometer." We observed that the application was easy to use and measured tilt each time. The result obtained can be documented, digitally saved and transferred. In 130 patients studied, we observed incidence of degree of tilt as follows: 6-8° tilt in 38 patients (29.23%), 8-10 in 36 patients (27.69%), 10-12 in 30 patients (23.08%), 12-14 in 12 patients (9.23%) and 14-16° tilt in 14 patients (10.77%). Use of application was received with enthusiasm by practicing anesthesiologists. Various possible uses of this application are discussed.

  19. Assessing the effects of lumbar posterior stabilization and fusion to vertebral bone density in stabilized and adjacent segments by using Hounsfield unit

    PubMed Central

    Öksüz, Erol; Deniz, Fatih Ersay; Demir, Osman

    2017-01-01

    Background Computed tomography (CT) with Hounsfield unit (HU) is being used with increasing frequency for determining bone density. Established correlations between HU and bone density have been shown in the literature. The aim of this retrospective study was to determine the bone density changes of the stabilized and adjacent segment vertebral bodies by comparing HU values before and after lumbar posterior stabilization. Methods Sixteen patients who had similar diagnosis of lumbar spondylosis and stenosis were evaluated in this study. Same surgical procedures were performed to all of the patients with L2-3-4-5 transpedicular screw fixation, fusion and L3-4 total laminectomy. Bone mineral density measurements were obtained with clinical CT. Measurements were obtained from stabilized and adjacent segment vertebral bodies. Densities of vertebral bodies were evaluated with HU before the surgeries and approximately one year after the surgeries. The preoperative HU value of each vertebra was compared with postoperative HU value of the same vertebrae by using statistical analysis. Results The HU values of vertebra in the stabilized and adjacent segments consistently decreased after the operations. There were significant differences between the preoperative HU values and the postoperative HU values of the all evaluated vertebral bodies in the stabilized and adjacent segments. Additionally first sacral vertebra HU values were found to be significantly higher than lumbar vertebra HU values in the preoperative group and postoperative group. Conclusions Decrease in the bone density of the adjacent segment vertebral bodies may be one of the major predisposing factors for adjacent segment disease (ASD). PMID:29354730

  20. Biomechanical performance of rigid compared to dynamic anterior cervical plating: analysis of adjacent upper and lower level compressive forces.

    PubMed

    Connor, David E; Shamieh, Khader Samer; Ogden, Alan L; Mukherjee, Debi P; Sin, Anthony; Nanda, Anil

    2012-12-01

    Dynamic anterior cervical plating is well established as a means of enhancing graft loading and subsequent arthrodesis. Current concerns center on the degree of adjacent-level stress induced by these systems. The aim of this study was to evaluate and compare the load transferred to adjacent levels for single-level anterior cervical discectomy and fusion utilizing rigid compared to dynamic anterior plating systems. Nine cadaveric adult human cervical spine specimens were subjected to range-of-motion testing prior to and following C5-C6 anterior cervical discectomy and fusion procedures. Interbody grafting was performed with human fibula tissue. Nondestructive biomechanical testing included flexion/extension and lateral bending loading modes. A constant displacement of 5mm was applied in each direction and the applied load was measured in newtons (N). Specimens were tested in the following order: intact, following discectomy, after rigid plating, then after dynamic plating. Adjacent level (C4-C5 [L(S)] and C6-C7 [L(I)]) compressive forces were measured using low profile load cells inserted into each disc space. The measured load values for plating systems were then normalized using values measured for the intact specimens. Mean loads transferred to L(S) and L(I) during forced flexion in specimens with rigid plating were 23.47 N and 8.76 N, respectively; while the corresponding values in specimens with dynamic plating were 18.55 N and 1.03 N, respectively. Dynamic plating yielded no significant change at L(I) and a 21.0% decrease in load at L(S) when compared with rigid plating, although the difference was not significant. The observed trend suggests that dynamic plating may diminish superior adjacent level compressive stresses. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Gold-Catalyzed Solid-Phase Synthesis of 3,4-Dihydropyrazin-2(1H)-ones: Relevant Pharmacophores and Peptide Backbone Constraints.

    PubMed

    Přibylka, Adam; Krchňák, Viktor

    2017-11-13

    Here, we report the efficient solid-phase synthesis of N-propargyl peptides using Fmoc-amino acids and propargyl alcohol as key building blocks. Gold-catalyzed nucleophilic addition to the triple bond induced C-N bond formation, which triggered intramolecular cyclization, yielding 1,3,4-trisubstituted-5-methyl-3,4-dihydropyrazin-2(1H)-ones. Conformations of acyclic and constrained peptides were compared using a two-step conformer distribution analysis at the molecular mechanics level and density functional theory. The results indicated that the incorporation of heterocyclic molecular scaffold into a short peptide sequence adopted extended conformation of peptide chain. The amide bond adjacent to the constraint did not show significant preference for either cis or trans isomerism. Prepared model compounds demonstrate a proof of concept for gold-catalyzed polymer-supported synthesis of variously substituted 3,4-dihydropyrazin-2(1H)-ones for applications in drug discovery and peptide backbone constraints.

  2. Long-term soil accumulation of chromium, copper, and arsenic adjacent to preservative-treated wood.

    Treesearch

    S. Lebow; D. Foster; J. Evans

    2004-01-01

    Chromated copper arsenate (CCA) treated wood has been used extensively in outdoor applications. The Environmental Protection Agency (EPA) and CCA producers recently reached an agreement to limit future use of CCA for some types of applications. One area of concern is the long-term accumulation of leached CCA in soil adjacent to treated wood structures. Interpreting...

  3. Do Mangroves Subsidize Carbon to Adjacent Mudflat Fish Communities?

    NASA Astrophysics Data System (ADS)

    Henkel, S.; Kasten, S.; Hartmann, J.; Staubwasser, M.; Hernandez, M. F.; West, L.; Midway, S. R.; Polito, M. J.

    2017-12-01

    Mangroves are often implicated as energetic sources for fisheries productivity. However, the validity of this connection still remains in contention. Stable isotopes may provide answers by tracking the use of specific basal carbon sources in fish and invertebrates living in mangrove-mudflat habitat mosaics. We analyzed 307 consumer samples representing n=44 fish and invertebrate species collected from mangrove forest creeks and adjacent mudflats in coastal Tanzania using bulk carbon and nitrogen stable isotope analysis. Given the proposed high productivity of mangrove habitats, we hypothesize that mudflat communities will have carbon stable isotope values similar to mangrove communities either through the flux of mangrove carbon into adjacent mudflats and/or via the movement of mudflat fish communities into and out of mangrove habitats. Alternatively, mangrove carbon is often refractory, which may result in mudflat communities with isotopic values that differ from those found in adjacent mangrove communities. This scenario would suggest limited carbon flow between mudflat and mangrove food webs and that the movement of fish into and out of mangrove habitats is related to shelter from predation more than feeding. Data analysis is ongoing to test these competing hypotheses. By understanding the contribution of mangrove carbon to adjacent habitats, managers in Tanzania can make better informed decisions regarding the protection of mangroves and the local fisheries, which are a crucial source of income and food.

  4. Diaphragm-Sparing Nerve Blocks for Shoulder Surgery.

    PubMed

    Tran, De Q H; Elgueta, Maria Francisca; Aliste, Julian; Finlayson, Roderick J

    Shoulder surgery can result in significant postoperative pain. Interscalene brachial plexus blocks (ISBs) constitute the current criterion standard for analgesia but may be contraindicated in patients with pulmonary pathology due to the inherent risk of phrenic nerve block and symptomatic hemidiaphragmatic paralysis. Although ultrasound-guided ISB with small volumes (5 mL), dilute local anesthetic (LA) concentrations, and LA injection 4 mm lateral to the brachial plexus have been shown to reduce the risk of phrenic nerve block, no single intervention can decrease its incidence below 20%. Ultrasound-guided supraclavicular blocks with LA injection posterolateral to the brachial plexus may anesthetize the shoulder without incidental diaphragmatic dysfunction, but further confirmatory trials are required. Ultrasound-guided C7 root blocks also seem to offer an attractive, diaphragm-sparing alternative to ISB. However, additional large-scale studies are needed to confirm their efficacy and to quantify the risk of periforaminal vascular breach. Combined axillary-suprascapular nerve blocks may provide adequate postoperative analgesia for minor shoulder surgery but do not compare favorably to ISB for major surgical procedures. One intriguing solution lies in the combined use of infraclavicular brachial plexus blocks and suprascapular nerve blocks. Theoretically, the infraclavicular approach targets the posterior and lateral cords, thus anesthetizing the axillary nerve (which supplies the anterior and posterior shoulder joint), as well as the subscapular and lateral pectoral nerves (both of which supply the anterior shoulder joint), whereas the suprascapular nerve block anesthetizes the posterior shoulder. Future randomized trials are required to validate the efficacy of combined infraclavicular-suprascapular blocks for shoulder surgery.

  5. Why Do Students Switch from One University to Another: The View of Students Studying for a Foreign Degree in Hong Kong

    ERIC Educational Resources Information Center

    Willis, Mike

    2005-01-01

    Over 300 Foreign (non Hong Kong) universities deliver undergraduate degree programs in Hong Kong either on campus in that city or via distance education (or both). Although this topic has been studied from a variety of perspectives, the issue of why Hong Kong students might switch from one locally provided foreign university program to another has…

  6. Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery.

    PubMed

    Charlton, Shona; Cyna, Allan M; Middleton, Philippa; Griffiths, James D

    2010-12-08

    The transversus abdominis plane (TAP) block is a peripheral nerve block which anaesthetises the abdominal wall. The increasing use of TAP block, as a form of pain relief after abdominal surgery warrants evaluation of its effectiveness as an adjunctive technique to routine care and, when compared with other analgesic techniques. To assess effects of TAP blocks (and variants) on postoperative analgesia requirements after abdominal surgery. We searched specialised registers of Cochrane Anaesthesia and Cochrane Pain, Palliative and Supportive Care Review Groups, CENTRAL, MEDLINE, EMBASE and CINAHL to June 2010. We included randomised controlled trials (RCTs) comparing TAP block or rectus sheath block with: no TAP or rectus sheath block; placebo; systemic, epidural or any other analgesia. At least two review authors assessed study eligibility and risk of bias, and extracted data. We included eight studies (358 participants), five assessing TAP blocks, three assessing rectus sheath blocks; with moderate risk of bias overall. All studies had a background of general anaesthesia in both arms in most cases.Compared with no TAP block or saline placebo, TAP block resulted in significantly less postoperative requirement for morphine at 24 hours (mean difference (MD) -21.95 mg, 95% confidence interval (CI) -37.91 to 5.96; five studies, 236 participants) and 48 hours (MD -28.50, 95% CI -38.92 to -18.08; one study of 50 participants) but not at two hours (all random-effects analyses). Pain at rest was significantly reduced in two studies, but not a third.Only one of three included studies of rectus sheath blocks found a reduction in postoperative analgesic requirements in participants receiving blocks. One study, assessing number of participants who were pain-free after their surgery, found more participants who received a rectus sheath block to be pain-free for up to 10 hours postoperatively. As with TAP blocks, rectus sheath blocks made no apparent impact on nausea and vomiting

  7. Locking mechanisms in degree-4 vertex origami structures

    NASA Astrophysics Data System (ADS)

    Fang, Hongbin; Li, Suyi; Xu, Jian; Wang, K. W.

    2016-04-01

    Origami has emerged as a potential tool for the design of mechanical metamaterials and metastructures whose novel properties originate from their crease patterns. Most of the attention in origami engineering has focused on the wellknown Miura-Ori, a folded tessellation that is flat-foldable for folded sheet and stacked blocks. This study advances the state of the art and expands the research field to investigate generic degree-4 vertex (4-vertex) origami, with a focus on facet-binding. In order to understand how facet-binding attributes to the mechanical properties of 4-vertex origami structures, geometries of the 4-vertex origami cells are analyzed and analytically expressed. Through repeating and stacking 4-vertex cells, origami sheets and stacked origami blocks can be constructed. Geometry analyses discover four mechanisms that will lead to the self-locking of 4-vertex origami cells, sheets, and stacked blocks: in-cell facet-binding, inlayer facet-binding, inter-layer facet binding, and in-layer and inter-layer facet-bindings. These mechanisms and the predicted self-locking phenomena are verified through 3D simulations and prototype experiments. Finally, this paper briefly introduces the unusual mechanical properties caused by the locking of 4-vertex origami structures. The research reported in this paper could foster a new breed of self-locking structures with various engineering applications.

  8. Algorithm and Application of Gcp-Independent Block Adjustment for Super Large-Scale Domestic High Resolution Optical Satellite Imagery

    NASA Astrophysics Data System (ADS)

    Sun, Y. S.; Zhang, L.; Xu, B.; Zhang, Y.

    2018-04-01

    The accurate positioning of optical satellite image without control is the precondition for remote sensing application and small/medium scale mapping in large abroad areas or with large-scale images. In this paper, aiming at the geometric features of optical satellite image, based on a widely used optimization method of constraint problem which is called Alternating Direction Method of Multipliers (ADMM) and RFM least-squares block adjustment, we propose a GCP independent block adjustment method for the large-scale domestic high resolution optical satellite image - GISIBA (GCP-Independent Satellite Imagery Block Adjustment), which is easy to parallelize and highly efficient. In this method, the virtual "average" control points are built to solve the rank defect problem and qualitative and quantitative analysis in block adjustment without control. The test results prove that the horizontal and vertical accuracy of multi-covered and multi-temporal satellite images are better than 10 m and 6 m. Meanwhile the mosaic problem of the adjacent areas in large area DOM production can be solved if the public geographic information data is introduced as horizontal and vertical constraints in the block adjustment process. Finally, through the experiments by using GF-1 and ZY-3 satellite images over several typical test areas, the reliability, accuracy and performance of our developed procedure will be presented and studied in this paper.

  9. Properties of concrete blocks prepared with low grade recycled aggregates.

    PubMed

    Poon, Chi-Sun; Kou, Shi-cong; Wan, Hui-wen; Etxeberria, Miren

    2009-08-01

    Low grade recycled aggregates obtained from a construction waste sorting facility were tested to assess the feasibility of using these in the production of concrete blocks. The characteristics of the sorted construction waste are significantly different from that of crushed concrete rubbles that are mostly derived from demolition waste streams. This is due to the presence of higher percentages of non-concrete components (e.g. >10% soil, brick, tiles etc.) in the sorted construction waste. In the study reported in this paper, three series of concrete block mixtures were prepared by using the low grade recycled aggregates to replace (i) natural coarse granite (10mm), and (ii) 0, 25, 50, 75 and 100% replacement levels of crushed stone fine (crushed natural granite <5mm) in the concrete blocks. Test results on properties such as density, compressive strength, transverse strength and drying shrinkage as well as strength reduction after exposure to 800 degrees C are presented below. The results show that the soil content in the recycled fine aggregate was an important factor in affecting the properties of the blocks produced and the mechanical strength deceased with increasing low grade recycled fine aggregate content. But the higher soil content in the recycled aggregates reduced the reduction of compressive strength of the blocks after exposure to high temperature due probably to the formation of a new crystalline phase. The results show that the low grade recycled aggregates obtained from the construction waste sorting facility has potential to be used as aggregates for making non-structural pre-cast concrete blocks.

  10. Population Blocks.

    ERIC Educational Resources Information Center

    Smith, Martin H.

    1992-01-01

    Describes an educational game called "Population Blocks" that is designed to illustrate the concept of exponential growth of the human population and some potential effects of overpopulation. The game material consists of wooden blocks; 18 blocks are painted green (representing land), 7 are painted blue (representing water); and the remaining…

  11. Adjacent-Categories Mokken Models for Rater-Mediated Assessments

    PubMed Central

    Wind, Stefanie A.

    2016-01-01

    Molenaar extended Mokken’s original probabilistic-nonparametric scaling models for use with polytomous data. These polytomous extensions of Mokken’s original scaling procedure have facilitated the use of Mokken scale analysis as an approach to exploring fundamental measurement properties across a variety of domains in which polytomous ratings are used, including rater-mediated educational assessments. Because their underlying item step response functions (i.e., category response functions) are defined using cumulative probabilities, polytomous Mokken models can be classified as cumulative models based on the classifications of polytomous item response theory models proposed by several scholars. In order to permit a closer conceptual alignment with educational performance assessments, this study presents an adjacent-categories variation on the polytomous monotone homogeneity and double monotonicity models. Data from a large-scale rater-mediated writing assessment are used to illustrate the adjacent-categories approach, and results are compared with the original formulations. Major findings suggest that the adjacent-categories models provide additional diagnostic information related to individual raters’ use of rating scale categories that is not observed under the original formulation. Implications are discussed in terms of methods for evaluating rating quality. PMID:29795916

  12. 33 CFR 148.217 - How can a State be designated as an adjacent coastal State?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications... as an adjacent coastal State in the notice may request to be designated as one if the environmental risks to it are equal to or greater than the risks posed to a State directly connected by pipeline to...

  13. Genetic organization of the unc-22 IV gene and the adjacent region in Caenorhabditis elegans.

    PubMed

    Rogalski, T M; Baillie, D L

    1985-01-01

    The genetic organization of the region immediately adjacent to the unc-22 IV gene in Caenorhabditis elegans has been studied. We have identified twenty essential genes in this interval of approximately 1.5-map units on Linkage Group IV. The mutations that define these genes were positioned by recombination mapping and complementation with several deficiencies. With few exceptions, the positions obtained by these two methods agreed. Eight of the twenty essential genes identified are represented by more than one allele. Three possible internal deletions of the unc-22 gene have been located by intra-genic mapping. In addition, the right end point of a deficiency or an inversion affecting the adjacent genes let-56 and unc-22 has been positioned inside the unc-22 gene.

  14. Formation of cage-like particles by poly(amino acid)-based block copolymers in aqueous solution.

    PubMed Central

    Cudd, A; Bhogal, M; O'Mullane, J; Goddard, P

    1991-01-01

    When dissolved in N,N-dimethylformamide and then dialyzed against phosphate-buffered saline, A-B-A block copolymers composed of poly [N5-(2-hydroxyethyl)-L-glutamine]-block-poly(gamma-benzyl-L-glutamate)- block-poly [N5-(2-hydroxyethyl)-L-glutamine] form particles. The particles are cage-like structures with average diameters of 300 nm (average polydispersity, 0.3-0.5). They are stable in aqueous solution at 4 degrees C for up to 3 weeks, at which time flocculation becomes apparent. Negative staining and freeze-fracture electron microscopy suggest that cage-like particles are formed by selective association of segregated micelle populations. A model of particle formation is presented in which B blocks form micelles in dimethylformamide. On dialysis against an aqueous solution, the extended A blocks then associate intermolecularly to form rod-shaped micelles, which connect the B block micelles. The result is a meshed cage-like particle. The implications of these observations on the aggregation behavior of polymeric surfactants in dilute solution are discussed. Images PMID:11607245

  15. Making Nasopalatine Blocks Comfortable: A Randomised Prospective Clinical Comparison of Pain Associated with the Injection Using an Insulin Syringe and a Standard Disposable 3 mL Syringe.

    PubMed

    Prabhu, Sundararaman; Faizel, Syed; Pahlajani, Vedant; Prabhu, Shweta Jha

    2013-12-01

    This study was conducted to compare and evaluate the pain associated with administration of Nasopalatine blocks using a disposable insulin syringe and the conventional disposable 3 mL syringe. Forty patients requiring intraalveolar extractions of maxillary central incisors were randomly assigned to two groups of 20 patients each; one (Group A) received the nasopalatine block with a standard 3mL syringe and the other (Group B) received the block with an insulin syringe. Patients were asked to rate the pain associated with the injection on a visual analog scale (VAS) and the results were analysed using a Chi Square Test. The mean VAS score for Group A and B was 1.55 and 1 respectively. Chi Square value was calculated to be 8.603 (degree of freedom= 3, P value= 0.0351). There were no differences in the effectiveness of anesthesia between the groups. Pain associated with administration of the nasopalatine blocks may be significantly mitigated by using the Insulin syringe.

  16. The California Community College Baccalaureate Degree Pilot Program: A Case Study of Baccalaureate Degree Implementation

    ERIC Educational Resources Information Center

    Yeager, Susan Cadavid

    2017-01-01

    This case study examined the implementation of a baccalaureate degree at Skyline Community College--one of the 15 California community colleges authorized to offer baccalaureate degrees established as part of a pilot program enacted by the California Legislature via Senate Bill 850 (2014). The study explored the policies and procedures in place at…

  17. Physics Bachelor's One Year after Degree: Data from the Degree Recipient Follow-Up Survey for the Classes of 2011 and 2012 Combined. Focus On

    ERIC Educational Resources Information Center

    Tesfaye, Casey Langer; Mulvey, Patrick

    2014-01-01

    Each fall, the Statistical Research Center conducts the "Survey of Enrollments and Degrees," which asks physics and astronomy departments to provide information concerning the number of students they have enrolled and counts of recent degree recipients. In connection with this survey, the names and contact information for their recent…

  18. View of cell block eight (left), cell block seven, and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of cell block eight (left), cell block seven, and southwest guard tower, looking from cell block eight roof - Eastern State Penitentiary, 2125 Fairmount Avenue, Philadelphia, Philadelphia County, PA

  19. Cell block eleven (left) and cell block fifteen, looking from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Cell block eleven (left) and cell block fifteen, looking from cell block two into the "Death Row" exercise yard - Eastern State Penitentiary, 2125 Fairmount Avenue, Philadelphia, Philadelphia County, PA

  20. Mutant p53 expression in kidney tubules adjacent to renal cell carcinoma: evidence of a precursor lesion.

    PubMed

    Lai, R; el Dabbagh, L; Mourad, W A

    1996-06-01

    Neoplastic transformation can be associated with mutations of the p53 gene. This leads to stabilization of its protein product and to its accumulation, which allows immunohistochemical detection. Mutant p53 expression has been seen in many neoplasms, including renal cell carcinoma (RCC). We recently described putative precursor lesions of RCC. The lesions were defined as intratubular epithelial dysplasia (IED) of kidney tubules adjacent to RCC. They were seen in one-third of the cases studied. The findings were based only on light microscopic analysis. We hypothesized that neoplastic transformation would be manifested by mutant p53 expression in the kidney tubules adjacent to RCC and not in nonneoplastic kidneys. Immunohistochemical staining for p53 in 24 cases of RCC with adjacent kidneys was performed. We used the DO-7 monoclonal antibody reactive for the N-terminal of the p53 protein on formalin-fixed paraffin-embedded tissue. Sections from 14 kidneys resected for nonneoplastic conditions were used as controls. Twenty-one (87%) of the 24 cases of RCC had nuclear p53 expression in the tumor cells. This included 14 cases (58%) with intense reactivity and 7 cases (29%) with weaker p53 immunoreactivity. Of the 24 cases of RCC, IED was identified in 13 cases (54%). Immunoreactivity for p53 was focally seen in tubules of all the lesions, as well as in the nonlesional areas. Six of the lesions exhibited intense nuclear staining. The kidneys adjacent to the RCC, with no evidence of IED, showed focally intense positive p53 nuclear staining in four cases. None of the control specimens showed p53 expression. Our findings provide supportive evidence that previously described IED in kidneys adjacent to RCC are most likely precursor lesions of the neoplasm. Aberrant expression of p53 in areas without evidence of IED may suggest that neoplastic transformation manifested by p53 mutation in kidney tubules may be seen before the development of the morphologic features of

  1. S-band microwave radiation by a high-impedance diode with an A6 anode block

    NASA Astrophysics Data System (ADS)

    Sayapin, A.; Dai, U.; Krasik, Ya. E.

    2017-12-01

    The results of experimental research of the intensity distribution of microwave fields in the resonant cavities of an A6 anode block with a high-impedance (≥120 Ω) magnetically insulated electron diode powered by a Linear Induction Accelerator (LIA) (˜350 kV, ˜2.5 kA, 150 ns) are presented. The power and duration of the microwave pulses obtained from one cavity varied in the range of 200-300 MW and 120-50 ns, respectively, depending on the charging voltage of the LIA and the value of the axial magnetic field. It was found that the field intensity in cavities adjacent to the extraction cavity differs by ˜3 times and that the field intensity gradually increases along the series of cavities. The direction of this increase coincides with the direction of the electrons' E ×B drift, i.e., the change in the magnetic field direction results in the change in the direction of the increase in the intensity of the field in the cavities.

  2. Automatic extraction of blocks from 3D point clouds of fractured rock

    NASA Astrophysics Data System (ADS)

    Chen, Na; Kemeny, John; Jiang, Qinghui; Pan, Zhiwen

    2017-12-01

    This paper presents a new method for extracting blocks and calculating block size automatically from rock surface 3D point clouds. Block size is an important rock mass characteristic and forms the basis for several rock mass classification schemes. The proposed method consists of four steps: 1) the automatic extraction of discontinuities using an improved Ransac Shape Detection method, 2) the calculation of discontinuity intersections based on plane geometry, 3) the extraction of block candidates based on three discontinuities intersecting one another to form corners, and 4) the identification of "true" blocks using an improved Floodfill algorithm. The calculated block sizes were compared with manual measurements in two case studies, one with fabricated cardboard blocks and the other from an actual rock mass outcrop. The results demonstrate that the proposed method is accurate and overcomes the inaccuracies, safety hazards, and biases of traditional techniques.

  3. Transversus Abdominis Plane Block versus Ilioinguinal/Iliohypogastric Nerve Block with Wound Infiltration for Postoperative Analgesia in Inguinal Hernia Surgery: A Randomized Clinical Trial.

    PubMed

    Sujatha, Chinthavali; Zachariah, Mamie; Ranjan, R V; George, Sagiev Koshy; Ramachandran, T R; Pillai, Anil Radhakrishna

    2017-01-01

    Various analgesic modalities have been used for postoperative analgesia in patients undergoing inguinal hernia surgery. In this randomized clinical trial, we have compared the analgesic efficacy of transversus abdominis plane (TAP) block with that of ilioinguinal/iliohypogastric (IIIH) nerve block with wound infiltration in patients undergoing unilateral open inguinal hernia repair. The primary objective of this study was to compare the efficacy of postoperative analgesia of ultrasound-guided TAP block and IIIH block with wound infiltration (WI) in patients undergoing open inguinal hernia surgery. This was a randomized clinical trial performed in a tertiary care hospital. Sixty patients scheduled for hernia repair were randomized into two groups, Group T and Group I. Postoperatively, under ultrasound guidance, Group T received 20 ml of 0.25% ropivacaine - TAP block and Group I received 10 ml of 0.25% ropivacaine - IIIH block + WI with 10 ml of 0.25% ropivacaine. The primary outcome measure was the time to rescue analgesia in the first 24 h postoperatively. Fentanyl along with diclofenac was given as first rescue analgesic when the patient complained of pain. Statistical comparisons were performed using Student's t -test and Chi-square test. Mean time to rescue analgesia was 5.900 ± 1.881 h and 3.766 ± 1.754 h ( P < 0.001) and the mean pain scores were 5.73 ± 0.784 and 6.03 ± 0.850 for Group TAP and IIIH + WI, respectively. Hemodynamics were stable in both the groups. One-third of the patients received one dose of paracetamol in addition to the rescue analgesic in the first 24 h. There were no complications attributed to the block. As a multimodal analgesic regimen, definitely both TAP block and IIIH block with wound infiltration have a supporting role in providing analgesia in the postoperative period for adult inguinal hernia repair. In this study, ultrasound-guided TAP block provided longer pain control postoperatively than IIIH block with WI after inguinal

  4. Eelgrass Meadows in the California Channel Islands and Adjacent Coast Reveal a Mosaic of Two Species, Evidence for Introgression and Variable Clonality

    PubMed Central

    Coyer, J. A.; Miller, K. A.; Engle, J. M.; Veldsink, J.; Cabello-Pasini, A.; Stam, W. T.; Olsen, J. L.

    2008-01-01

    Background and Aims Seagrasses are important facilitator species in shallow, soft-bottom marine environments worldwide and, in many places, are threatened by coastal development and eutrophication. One narrow-leaved species (Zostera marina) and one wide-leaved species, variously designated as Z. marina, Z. pacifica or Z. asiatica, are found off the California Channel Islands and adjacent California–Mexico coast. The aim of the present study was to confirm species identification genetically and to link patterns of genetic diversity, connectivity and hybridization among and within the populations with historical sea levels (Ice Age) or the contemporary environment. Methods Samples (n = 11–100) were collected from 28 sites off five California Channel Islands and six sites off the adjacent coast of southern California and Baja California, Mexico. DNA polymorphisms of the rDNA-ITS (internal transcribed spacer) cistron (nuclear), the matK intron (chloroplast) and nine microsatellite loci (nuclear) were examined in a population genetic and phylogeographic context. Key Results All wide-leaved individuals were Z. pacifica, whereas narrow-leaved forms were Z. marina. Microsatellite genotypes were consistent with hybridization between the two species in three populations. The present distribution of Z. pacifica follows a glacial age land mass rather than present oceanographic regimes, but no link was observed between the present distribution of Z. marina and past or present environments. Island populations of Z. marina often were clonal and characterized by low genotypic diversity compared with populations along the Baja California coast. The high level of clonal connectivity around Santa Catalina Island indicated the importance of dispersal and subsequent re-establishment of vegetative fragments. Conclusions The pristine environmental conditions of offshore islands do not guarantee maximum genetic diversity. Future restoration and transplantation efforts of seagrasses

  5. Self-Assembly of Rod-Coil Block Copolymers on Carbon Nanotubes: A Route toward Diverse Surface Nanostructures.

    PubMed

    Han, Yang; Cai, Chunhua; Lin, Jiaping; Gong, Shuting; Xu, Wenheng; Hu, Rui

    2018-04-14

    In this work, it is reported that poly(γ-benzyl-l-glutamate)-block-poly(ethylene glycol) (PBLG-b-PEG) rod-coil block copolymers (BCPs) can disperse carbon nanotubes (CNTs) in solution and form various surface nanostructures on the CNTs via solution self-assembly. In an organic solvent that dissolves the BCPs, the PBLG rod blocks adsorb on CNT surfaces, and the BCPs form conformal coatings. Then, by the introduction of water, a selective solvent for PEG blocks, the BCPs in the coatings further self-assemble into diverse surface nanostructures, such as helices (left-handed or right-handed), gyros, spheres, and rings. The morphology of the surface nanostructure can be tailored by initial organic solvent composition, preparation temperature, feeding ratio of BCPs to CNTs, degree of polymerization of PBLG blocks, and diameter of the CNTs. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Conformal blocks from Wilson lines with loop corrections

    NASA Astrophysics Data System (ADS)

    Hikida, Yasuaki; Uetoko, Takahiro

    2018-04-01

    We compute the conformal blocks of the Virasoro minimal model or its WN extension with large central charge from Wilson line networks in a Chern-Simons theory including loop corrections. In our previous work, we offered a prescription to regularize divergences from loops attached to Wilson lines. In this paper, we generalize our method with the prescription by dealing with more general operators for N =3 and apply it to the identity W3 block. We further compute general light-light blocks and heavy-light correlators for N =2 with the Wilson line method and compare the results with known ones obtained using a different prescription. We briefly discuss general W3 blocks.

  7. 75 FR 65278 - Pamlico Sound and Adjacent Waters, NC; Danger Zones for Marine Corps Operations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... DEPARTMENT OF DEFENSE Corps of Engineers, Department of the Army 33 CFR Part 334 Pamlico Sound and... (Corps) is proposing to amend its regulations to establish one new danger zone in Pamlico Sound near... described in Sec. 334.420(b)(1)(i)] in the Pamlico Sound and adjacent waters in Carteret County, North...

  8. Map showing distribution of bismuth and cadmium in stream-sediment samples, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle shows the regional distribution of bismuth and cadimum in the less-than-0.180-mm (minus-80-mesh) fraction of stream sediments. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess the mineral

  9. Block Transfer Handbook: Constructing and Negotiating Block Transfer Agreements.

    ERIC Educational Resources Information Center

    Finlay, Finola

    The purpose of this handbook is to provide resources for institutions or articulation committees who are engaged in the task of investigating the feasibility of block transfer agreements. Block transfer is the process whereby a block of credits is granted to students who have successfully completed a certificate, diploma, or cluster of courses…

  10. Mutations affecting two adjacent amino acid residues in the alpha subunit of RNA polymerase block transcriptional activation by the bacteriophage P2 Ogr protein.

    PubMed Central

    Ayers, D J; Sunshine, M G; Six, E W; Christie, G E

    1994-01-01

    The bacteriophage P2 ogr gene product is a positive regulator of transcription from P2 late promoters. The ogr gene was originally defined by compensatory mutations that overcame the block to P2 growth imposed by a host mutation, rpoA109, in the gene encoding the alpha subunit of RNA polymerase. DNA sequence analysis has confirmed that this mutation affects the C-terminal region of the alpha subunit, changing a leucine residue at position 290 to a histidine (rpoAL290H). We have employed a reporter plasmid system to screen other, previously described, rpoA mutants for effects on activation of a P2 late promoter and have identified a second allele, rpoA155, that blocks P2 late transcription. This mutation lies just upstream of rpoAL290H, changing the leucine residue at position 289 to a phenylalanine (rpoAL289F). The effect of the rpoAL289F mutation is not suppressed by the rpoAL290H-compensatory P2 ogr mutation. P2 ogr mutants that overcome the block imposed by rpoAL289F were isolated and characterized. Our results are consistent with a direct interaction between Ogr and the alpha subunit of RNA polymerase and support a model in which transcription factor contact sites within the C terminus of alpha are discrete and tightly clustered. PMID:8002564

  11. Block Preconditioning to Enable Physics-Compatible Implicit Multifluid Plasma Simulations

    NASA Astrophysics Data System (ADS)

    Phillips, Edward; Shadid, John; Cyr, Eric; Miller, Sean

    2017-10-01

    Multifluid plasma simulations involve large systems of partial differential equations in which many time-scales ranging over many orders of magnitude arise. Since the fastest of these time-scales may set a restrictively small time-step limit for explicit methods, the use of implicit or implicit-explicit time integrators can be more tractable for obtaining dynamics at time-scales of interest. Furthermore, to enforce properties such as charge conservation and divergence-free magnetic field, mixed discretizations using volume, nodal, edge-based, and face-based degrees of freedom are often employed in some form. Together with the presence of stiff modes due to integrating over fast time-scales, the mixed discretization makes the required linear solves for implicit methods particularly difficult for black box and monolithic solvers. This work presents a block preconditioning strategy for multifluid plasma systems that segregates the linear system based on discretization type and approximates off-diagonal coupling in block diagonal Schur complement operators. By employing multilevel methods for the block diagonal subsolves, this strategy yields algorithmic and parallel scalability which we demonstrate on a range of problems.

  12. Laramide structure of the central Sangre de Cristo Mountains and adjacent Raton Basin, southern Colorado

    USGS Publications Warehouse

    Lindsey, D.A.

    1998-01-01

    Laramide structure of the central Sangre de Cristo Mountains (Culebra Range) is interpreted as a system of west-dipping, basement-involved thrusts and reverse faults. The Culebra thrust is the dominant structure in the central part of the range; it dips 30 -55?? west and brings Precambrian metamorphic base-ment rocks over unmetamorphosed Paleozoic rocks. East of the Culebra thrust, thrusts and reverse faults break the basement and overlying cover rocks into north-trending fault blocks; these boundary faults probably dip 40-60?? westward. The orientation of fault slickensides indicates oblique (northeast) slip on the Culebra thrust and dip-slip (ranging from eastward to northward) movement on adjacent faults. In sedimentary cover rocks, east-vergent anticlines overlie and merge with thrusts and reverse faults; these anticlines are interpreted as fault-propagation folds. Minor east-dipping thrusts and reverse faults (backthrusts) occur in both the hanging walls and footwalls of thrusts. The easternmost faults and folds of the Culebra Range form a continuous structural boundary between the Laramide Sangre de Cristo highland and the Raton Basin. Boundary structures consist of west-dipping frontal thrusts flanked on the basinward side by poorly exposed, east-dipping backthrusts. The backthrusts are interpreted to overlie structural wedges that have been emplaced above blind thrusts in the basin margin. West-dipping frontal thrusts and blind thrusts are interpreted to involve basement, but backthrusts are rooted in basin-margin cover rocks. At shallow structural levels where erosion has not exposed a frontal thrust, the structural boundary of the basin is represented by an anticline or monocline. Based on both regional and local stratigraphic evidence, Laramide deformation in the Culebra Range and accompanying synorogenic sedimentation in the western Raton Basin probably took place from latest Cretaceous through early Eocene time. The earliest evidence of uplift and

  13. Effect of Lumbar Lordosis on the Adjacent Segment in Transforaminal Lumbar Interbody Fusion: A Finite Element Analysis.

    PubMed

    Zhao, Xin; Du, Lin; Xie, Youzhuan; Zhao, Jie

    2018-06-01

    We used a finite element (FE) analysis to investigate the biomechanical changes caused by transforaminal lumbar interbody fusion (TLIF) at the L4-L5 level by lumbar lordosis (LL) degree. A lumbar FE model (L1-S5) was constructed based on computed tomography scans of a 30-year-old healthy male volunteer (pelvic incidence,= 50°; LL, 52°). We investigated the influence of LL on the biomechanical behavior of the lumbar spine after TLIF in L4-L5 fusion models with 57°, 52°, 47°, and 40° LL. The LL was defined as the angle between the superior end plate of L1 and the superior end plate of S1. A 150-N vertical axial preload was imposed on the superior surface of L3. A 10-N/m moment was simultaneously applied on the L3 superior surface along the radial direction to simulate the 4 basic physiologic motions of flexion, extension, lateral bending, and torsion in the numeric simulations. The range of motion (ROM) and intradiscal pressure (IDP) of L3-L4 were evaluated and compared in the simulated cases. In all motion patterns, the ROM and IDP were both increased after TLIF. In addition, the decrease in lordosis generally increased the ROM and IDP in all motion patterns. This FE analysis indicated that decreased spinal lordosis may evoke overstress of the adjacent segment and increase the risk of the pathologic development of adjacent segment degeneration; thus, adjacent segment degeneration should be considered when planning a spinal fusion procedure. Copyright © 2018. Published by Elsevier Inc.

  14. Analysis of the width-[Formula: see text] non-adjacent form in conjunction with hyperelliptic curve cryptography and with lattices.

    PubMed

    Krenn, Daniel

    2013-06-17

    In this work the number of occurrences of a fixed non-zero digit in the width-[Formula: see text] non-adjacent forms of all elements of a lattice in some region (e.g. a ball) is analysed. As bases, expanding endomorphisms with eigenvalues of the same absolute value are allowed. Applications of the main result are on numeral systems with an algebraic integer as base. Those come from efficient scalar multiplication methods (Frobenius-and-add methods) in hyperelliptic curves cryptography, and the result is needed for analysing the running time of such algorithms. The counting result itself is an asymptotic formula, where its main term coincides with the full block length analysis. In its second order term a periodic fluctuation is exhibited. The proof follows Delange's method.

  15. Characterizing permanent magnet blocks with Helmholtz coils

    NASA Astrophysics Data System (ADS)

    Carnegie, D. W.; Timpf, J.

    1992-08-01

    Most of the insertion devices to be installed at the Advanced Photon Source will utilize permanent magnets in their magnetic structures. The quality of the spectral output is sensitive to the errors in the field of the device which are related to variations in the magnetic properties of the individual blocks. The Advanced Photon Source will have a measurement facility to map the field in the completed insertion devices and equipment to test and modify the magnetic strength of the individual magnet blocks. One component of the facility, the Helmholtz coil permanent magnet block measurement system, has been assembled and tested. This system measures the total magnetic moment vector of a block with a precision better than 0.01% and a directional resolution of about 0.05°. The design and performance of the system will be presented.

  16. East Cameron Block 270, a Pleistocene field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holland, D.S.; Sutley, C.E.; Berlitz, R.E.

    1974-01-01

    Exploration of the Plio-Pleistocene in the Gulf of Mexico since 1970 has discovered significant hydrocarbon reserves. One of the better gas fields to date has been the Block 270 E. Cameron field. Utilization of a coordinated exploitation plan with Schlumberger has allowed Pennzoil as operator, to develop and put on production the Block 270 field in a minimum time period. Block 270 field is a N.-S. trending faulted nose at 6,000 ft. At G-Sand depth (8,700 ft), the structure has closed, forming an elongated N.-S. structure with dip in all directions from the Block 270 area. Closure is the resultmore » of contemporaneous growth on the E. bounding regional fault. Structural and stratigraphic interpretations from dipmeters were used to help determine the most favorable offset locations.« less

  17. Ice Block Avalanche

    NASA Image and Video Library

    2018-06-25

    One of the most actively changing areas on Mars are the steep edges of the North Polar layered deposits. This image from NASA's Mars Reconnaissance Orbiter (MRO) shows many new ice blocks compared to an earlier image in December 2006. An animation shows one example, where a section of ice cliff collapsed. The older image (acquired in bin-2 mode) is not as sharp as the newer one. HiRISE has been re-imaging regions first photographed in 2006 through 2007, six Mars years ago. This long baseline allows us to see large, rare changes as well as many smaller changes. More information is available at https://photojournal.jpl.nasa.gov/catalog/PIA22535

  18. Blocking contacts for N-type cadmium zinc telluride

    NASA Technical Reports Server (NTRS)

    Stahle, Carl M. (Inventor); Parker, Bradford H. (Inventor); Babu, Sachidananda R. (Inventor)

    2012-01-01

    A process for applying blocking contacts on an n-type CdZnTe specimen includes cleaning the CdZnTe specimen; etching the CdZnTe specimen; chemically surface treating the CdZnTe specimen; and depositing blocking metal on at least one of a cathode surface and an anode surface of the CdZnTe specimen.

  19. Stem and leaf hydraulics of congeneric tree species from adjacent tropical savanna and forest ecosystems

    Treesearch

    Guang You Hao; William A. Hoffmann; Fabian G. Scholz; Sandra J. Bucci; Frederick C. Meinzer; Augusto C. Franco; Kun Fang Cao; Guillermo Goldstein

    2008-01-01

    Leaf and stem functional traits related to plant water relations were studied for six congeneric species pairs, each composed of one tree species typical of savanna habitats and another typical of adjacent forest habitats, to determine whether there were intrinsic differences in plant hydraulics between these two functional types. Only individuals growing in savanna...

  20. The Doctor of Arts Degree.

    ERIC Educational Resources Information Center

    Koenker, Robert H.

    The Doctor of Arts (D.A.) degree is a degree specifically designed to prepare and train quality college teachers. The program leading to the D.A. is a rigorous one, and takes into account not only a candidates knowledge of a particular field but also his ability to relate his knowledge to others. This report takes into consideration the factors…

  1. View southeast of caps for blocks for JFK; blocks are ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast of caps for blocks for JFK; blocks are used to support ship when it is repositioned to paint inaccessible areas masked by original support blocks. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Carpentry Shop, League Island, Philadelphia, Philadelphia County, PA

  2. Effect of Augmentation Material Stiffness on Adjacent Vertebrae after Osteoporotic Vertebroplasty Using Finite Element Analysis with Different Loading Methods.

    PubMed

    Cho, Ah-Reum; Cho, Sang-Bong; Lee, Jae-Ho; Kim, Kyung-Hoon

    2015-11-01

    Vertebroplasty is an effective treatment for osteoporotic vertebral fractures, which are one of the most common fractures associated with osteoporosis. However, clinical observation has shown that the risk of adjacent vertebral body fractures may increase after vertebroplasty. The mechanism underlying adjacent vertebral body fracture after vertebroplasty is not clear; excessive stiffness resulting from polymethyl methacrylate has been suspected as an important mechanism. The aim of our study was to compare the effects of bone cement stiffness on adjacent vertebrae after osteoporotic vertebroplasty under load-controlled versus displacement-controlled conditions. An experimental computer study using a finite element analysis. Medical research institute, university hospital, Korean. A three-dimensional digital anatomic model of L1/2 bone structure was reconstructed from human computed tomographic images. The reconstructed three-dimensional geometry was processed for finite element analysis such as meshing elements and applying material properties. Two boundary conditions, load-controlled and displacement-controlled methods, were applied to each of 5 deformation modes: compression, flexion, extension, lateral bending, and torsion. The adjacent L1 vertebra, irrespective of augmentation, revealed nearly similar maximum von Mises stresses under the load-controlled condition. However, for the displacement-controlled condition, the maximum von Mises stresses in the cortical bone and inferior endplate of the adjacent L1 vertebra increased significantly after cement augmentation. This increase was more significant than that with stiffer bone cement under all modes, except the torsion mode. The finite element model was simplified, excluding muscular forces and incorporating a large volume of bone cement, to more clearly demonstrate effects of bone cement stiffness on adjacent vertebrae after vertebroplasty. Excessive stiffness of augmented bone cement increases the risk of

  3. Efficacy of paraspinal anesthetic block in patients with chronic pelvic pain refractory to drug therapy: a randomized clinical trial.

    PubMed

    da Rosa, Karen Felix; Amantéa, Vinícius Atrib; dos Santos, Antônio Cardoso; Savaris, Ricardo Francalacci

    2015-03-01

    To determine whether paraspinal block reduces pain scores compared to placebo in women with chronic pelvic pain refractory to drug therapy. Subjects with chronic pelvic pain due to benign conditions and refractory to drug therapy were invited to participate in a randomized, double blind, superiority trial at a tertiary reference center. Subjects were randomly allocated to receive paraspinal anesthetic block with 1% lidocaine without epinephrine or placebo (control). Lidocaine was injected along the spinal process of the painful segment in the supra- and interspinal ligaments using a 25G X 2" needle. Placebo consisted of introduction of the needle in the same segment without injecting any substance. The main outcome measured was the pain score based on a visual analog scale at T0 (baseline), T1 (within 15 min after the procedure) and T2 (one week after the procedure). Data were statistically analyzed by ANOVA and the 95% confidence interval (95%CI). Mean age was similar for both groups, i.e., 51.2 (paraspinal anesthetic block) and 51.8 years (control). A blind examiner measured the degree of pain according to the visual analog scale from 0 (no pain) to 10 (worst pain imaginable). Based on the visual analog scale, the mean pain scores of the paraspinal anesthetic block group at T0, T1 and T2 were 5.50 (SD=2.92; 95%CI 3.84-7.15), 2.72 (SD=2.10; 95%CI 1.53-3.90), and 4.36 (SD=2.37; 95%CI 1.89-6.82), respectively. The difference between T0 and T1 was statistically significant, with p=0.03. Paraspinal anesthetic block had a small effect on visual analog scale pain score immediately after the injections, but no sustained benefit after one week. Further studies are needed to determine the efficacy of paraspinal anesthetic block with different lidocaine doses for the treatment of visceral pain of other causes.

  4. Responsive linear-dendritic block copolymers.

    PubMed

    Blasco, Eva; Piñol, Milagros; Oriol, Luis

    2014-06-01

    The combination of dendritic and linear polymeric structures in the same macromolecule opens up new possibilities for the design of block copolymers and for applications of functional polymers that have self-assembly properties. There are three main strategies for the synthesis of linear-dendritic block copolymers (LDBCs) and, in particular, the emergence of click chemistry has made the coupling of preformed blocks one of the most efficient ways of obtaining libraries of LDBCs. In these materials, the periphery of the dendron can be precisely functionalised to obtain functional LDBCs with self-assembly properties of interest in different technological areas. The incorporation of stimuli-responsive moieties gives rise to smart materials that are generally processed as self-assemblies of amphiphilic LDBCs with a morphology that can be controlled by an external stimulus. Particular emphasis is placed on light-responsive LDBCs. Furthermore, a brief review of the biomedical or materials science applications of LDBCs is presented. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Responsive block copolymer photonics triggered by protein-polyelectrolyte coacervation.

    PubMed

    Fan, Yin; Tang, Shengchang; Thomas, Edwin L; Olsen, Bradley D

    2014-11-25

    Ionic interactions between proteins and polyelectrolytes are demonstrated as a method to trigger responsive transitions in block copolymer (BCP) photonic gels containing one neutral hydrophobic block and one cationic hydrophilic block. Poly(2-vinylpyridine) (P2VP) blocks in lamellar poly(styrene-b-2-vinylpyridine) block copolymer thin films are quaternized with primary bromides to yield swollen gels that show strong reflectivity peaks in the visible range; exposure to aqueous solutions of various proteins alters the swelling ratios of the quaternized P2VP (QP2VP) gel layers in the PS-QP2VP materials due to the ionic interactions between proteins and the polyelectrolyte. Parameters such as charge density, hydrophobicity, and cross-link density of the QP2VP gel layers as well as the charge and size of the proteins play significant roles on the photonic responses of the BCP gels. Differences in the size and pH-dependent charge of proteins provide a basis for fingerprinting proteins based on their temporal and equilibrium photonic response. The results demonstrate that the BCP gels and their photonic effect provide a robust and visually interpretable method to differentiate different proteins.

  6. A prospective, randomized evaluation of the effects of epidural needle rotation on the distribution of epidural block.

    PubMed

    Borghi, Battista; Agnoletti, Vanni; Ricci, Alessandro; van Oven, Hanna; Montone, Nicoletta; Casati, Andrea

    2004-05-01

    We evaluated the effects of turning the tip of the Tuohy needle 45 degrees toward the operative side before threading the epidural catheter (45 degrees -rotation group, n = 24) as compared to a conventional insertion technique with the tip of the Tuohy needle oriented at 90 degrees cephalad (control group, n = 24) on the distribution of 10 mL of 0.75% ropivacaine with 10 microg sufentanil in 48 patients undergoing total hip replacement. The catheter was introduced 3 to 4 cm beyond the tip of the Tuohy needle. A blinded observer recorded sensory and motor blocks on both sides, quality of analgesia, and volumes of local anesthetic used during the first 48 h of patient-controlled epidural analgesia. Readiness to surgery required 21 +/- 6 min in the control group and 17 +/- 7 min in the 45 degree-rotation group (P > 0.50). The maximum sensory level reached on the operative side was T10 (T10-7) in the control group and T9 (T10-6) in the 45 degree-rotation group (P > 0.50); whereas the maximum sensory level reached on the nonoperative side was T10 (T12-9) in the control group and L3 (L5-T12) in the 45 degree-rotation group (P = 0.0005). Complete motor blockade of the operative limb was achieved earlier in the 45 degree-rotation than in the control group, and motor block of the nonoperative side was more intense in patients in the control group. Two-segment regression of sensory level on the surgical side was similar in the two groups, but occurred earlier on the nonoperative side in the 45 degree-rotation group (94 +/- 70 min) than in the control group (178 +/- 40 min) (P = 0.0005). Postoperative analgesia was similar in the 2 groups, but the 45 degree-rotation group consumed less local anesthetic (242 +/- 35 mL) than the control group (297 +/- 60 mL) (P = 0.0005). We conclude that the rotation of the Tuohy introducer needle 45 degrees toward the operative side before threading the epidural catheter provides a preferential distribution of sensory and motor block toward

  7. Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia.

    PubMed

    Escobar-Diaz, Maria C; Tworetzky, Wayne; Friedman, Kevin; Lafranchi, Terra; Fynn-Thompson, Francis; Alexander, Mark E; Mah, Douglas Y

    2014-08-01

    Congenital atrioventricular (AV) block is commonly associated with heterotaxy syndrome; together they have reportedly low survival rates (10-25%). However, information about perinatal outcome and predictors of non-survival after prenatal diagnosis of this association is scarce. Therefore, we studied fetuses with heterotaxy syndrome and bradycardia or AV-block diagnosed between 1995 and 2011, and analyzed pre and post-natal variables. The primary outcome was death and the secondary outcome was pacemaker placement. Of the 154 fetuses with heterotaxy syndrome, 91 had polysplenia syndrome, 22/91(24%) with bradycardia or AV-block. Thirteen (59%) patients had sinus bradycardia at diagnosis, 8 (36%) complete AV block, and 1 (5%) second-degree AV-block. Three patients elected for termination of pregnancy (3/22, 14%), 4 had spontaneous fetal demise (4/22, 18%), and 15 (15/22, 68%) were live-born. Of the fetuses with bradycardia/AV-block, 30% presented with hydrops, 20% had ventricular rates <55 beats/min, and 10% had cardiac dysfunction. Excluding termination of pregnancy, 15/19 fetuses (79%) survived to birth. Among the 15 live-born patients, 4 had bradycardia and 11 had AV-block. A further 3 patients died in infancy, all with AV-block who required pacemakers in the neonatal period. Thus, the 1-year survival rate, excluding termination of pregnancy, was 63% (12/19). Of the remaining 12 patients, 9 required pacemaker. Predictors of perinatal death included hydrops (p < 0.0001), ventricular dysfunction (p = 0.002), prematurity (p = 0.04), and low ventricular rates (p = 0.04). In conclusion, we found a higher survival rate (63%) than previously published in patients with heterotaxy syndrome and AV block or bradycardia diagnosed prenatally. Hydrops, cardiac dysfunction, prematurity and low ventricular rates were predictors of death.

  8. Perinatal Outcome in Fetuses with Heterotaxy Syndrome and Atrioventricular Block or Bradycardia

    PubMed Central

    Tworetzky, Wayne; Friedman, Kevin; Lafranchi, Terra; Fynn-Thompson, Francis; Alexander, Mark E.; Mah, Douglas Y.

    2015-01-01

    Congenital atrioventricular (AV) block is commonly associated with heterotaxy syndrome; together they have reportedly low survival rates (10–25 %). However, information about perinatal outcome and predictors of nonsurvival after prenatal diagnosis of this association is scarce. Therefore, we studied fetuses with heterotaxy syndrome and bradycardia or AV-block diagnosed between 1995 and 2011, and analyzed pre and post-natal variables. The primary outcome was death and the secondary outcome was pacemaker placement. Of the 154 fetuses with heterotaxy syndrome, 91 had polysplenia syndrome, 22/91(24 %) with bradycardia or AV-block. Thirteen (59 %) patients had sinus bradycardia at diagnosis, 8 (36 %) complete AV block, and 1 (5 %) second-degree AV-block. Three patients elected for termination of pregnancy (3/22, 14 %), 4 had spontaneous fetal demise (4/22, 18 %), and 15 (15/22, 68 %) were live-born. Of the fetuses with bradycardia/AV-block, 30 % presented with hydrops, 20 % had ventricular rates <55 beats/min, and 10 % had cardiac dysfunction. Excluding termination of pregnancy, 15/19 fetuses (79 %) survived to birth. Among the 15 live-born patients, 4 had bradycardia and 11 had AV-block. A further 3 patients died in infancy, all with AV-block who required pacemakers in the neonatal period. Thus, the 1-year survival rate, excluding termination of pregnancy, was 63 % (12/19). Of the remaining 12 patients, 9 required pacemaker. Predictors of perinatal death included hydrops (p < 0.0001), ventricular dysfunction (p = 0.002), prematurity (p = 0.04), and low ventricular rates (p = 0.04). In conclusion, we found a higher survival rate (63 %) than previously published in patients with heterotaxy syndrome and AV block or bradycardia diagnosed prenatally. Hydrops, cardiac dysfunction, prematurity and low ventricular rates were predictors of death. PMID:24509635

  9. A Shifted Block Lanczos Algorithm 1: The Block Recurrence

    NASA Technical Reports Server (NTRS)

    Grimes, Roger G.; Lewis, John G.; Simon, Horst D.

    1990-01-01

    In this paper we describe a block Lanczos algorithm that is used as the key building block of a software package for the extraction of eigenvalues and eigenvectors of large sparse symmetric generalized eigenproblems. The software package comprises: a version of the block Lanczos algorithm specialized for spectrally transformed eigenproblems; an adaptive strategy for choosing shifts, and efficient codes for factoring large sparse symmetric indefinite matrices. This paper describes the algorithmic details of our block Lanczos recurrence. This uses a novel combination of block generalizations of several features that have only been investigated independently in the past. In particular new forms of partial reorthogonalization, selective reorthogonalization and local reorthogonalization are used, as is a new algorithm for obtaining the M-orthogonal factorization of a matrix. The heuristic shifting strategy, the integration with sparse linear equation solvers and numerical experience with the code are described in a companion paper.

  10. Environmental characteristics of the Grand Fir Mosaic and adjacent habitat types

    Treesearch

    Dennis E. Ferguson; John C. Byrne

    2000-01-01

    Grand Fir Mosaic habitats differ from adjacent forest habitats in their slow rate of secondary succession to woody vegetation. Remote monitoring stations were used to sample the environment at a Grand Fir Mosaic site and three adjacent habitat types. The Grand Fir Mosaic site has shorter growing seasons, cooler temperatures, and more soil moisture than the other sites...

  11. Strength of masonry blocks made with recycled concrete aggregates

    NASA Astrophysics Data System (ADS)

    Matar, Pierre; Dalati, Rouba El

    The idea of recycling concrete of demolished buildings aims at preserving the environment. Indeed, the reuse of concrete as aggregate in new concrete mixes helped to reduce the expenses related to construction and demolition (C&D) waste management and, especially, to protect the environment by reducing the development rate of new quarries. This paper presents the results of an experimental study conducted on masonry blocks containing aggregates resulting from concrete recycling. The purpose of this study is to investigate the effect of recycled aggregates on compressive strength of concrete blocks. Tests were performed on series of concrete blocks: five series each made of different proportions of recycled aggregates, and one series of reference blocks exclusively composed of natural aggregates. Tests showed that using recycled aggregates with addition of cement allows the production of concrete blocks with compressive strengths comparable to those obtained on concrete blocks made exclusively of natural aggregates.

  12. Toxicity and Bioavailability of Metals in the Missouri River Adjacent to a Lead Refinery

    DTIC Science & Technology

    2001-12-01

    Missouri River adjacent to the facility. Groundwater was also collected from the facility. Waters and sediments were analyzed for inorganic...highly elevated in the groundwater , but not in river sediment pore waters . Lead concentrations were moderately elevated in whole sediment at one site...but lead concentrations in pore waters were low due to apparent sequestration by acid-volatile sulfides. The groundwater sample was highly toxic to

  13. Planetary and synoptic-scale interactions during the life cycle of a mid-latitude blocking anticyclone over the North Atlantic

    NASA Technical Reports Server (NTRS)

    Smith, Phillip J.

    1995-01-01

    The formation of a blocking anticyclone over the North Atlantic has been examined over its entire life-CyCle using the Zwack-Okossi (Z-O) equation as the diagnostic tool. This blocking anticyclone occurred in late October and early November of 1985. The data used were provided by the NASA Goddard Laboratory for Atmospheres on a global 2.O degree latitude by 2.5 degree longitudinal grid. The horizontal distribution of the atmospheric forcing mechanisms that were important to 500 mb block formation, maintenance and decay were examined. A scale-partitioned form of the Z-O equation was then used to examine the relative importance of forcing on the planetary and synoptic scales, and their interactions. As seen in previous studies, the results presented here show that upper tropospheric anticyclonic vorticity advection was the most important contributor to block formation and maintenance. However, adiabatic warming, and vorticity tilting were also important at various times during the block lifetime. In association with precursor surface cyclogenesis, the 300 mb jet streak in the downstream (upstream) from a long-wave trough (ridge) amplified significantly. This strengthening of the jet streak enhanced the anti-cyclonic vorticity advection field that aided the amplification of a 500 mb short-wave ridge. Tile partitioned height tendency results demonstrate that the interactions between the planetary and sn,noptic-scale through vorticity advection was the most important contributor to block formation. Planetary-scale, synoptic-scale. and their interactions contributed weakly to the maintenance of the blocking anticyclone with the advection of synoptic-scale vorticity by the planetary-scale flow playing a more important role. Planetary-scale decay ofthe long-wave ridge contributed to the demise of this blocking event.

  14. MINARETS WILDERNESS AND ADJACENT AREAS, CALIFORNIA.

    USGS Publications Warehouse

    Huber, N. King; Thurber, Horace K.

    1984-01-01

    A mineral survey of the Minarets Wilderness and adjacent areas in the central Sierra Nevada, California was conducted. The results of the survey indicate that the study area has a substantiated resource potential for small deposits of copper, silver, zinc, lead, and iron, and a probable mineral-resource potential for molybdenum. No energy-resource potential was identified in the study.

  15. Block copolymer directed one-pot simple synthesis of L10-phase FePt nanoparticles inside ordered mesoporous aluminosilicate/carbon composites.

    PubMed

    Kang, Eunae; Jung, Hyunok; Park, Je-Geun; Kwon, Seungchul; Shim, Jongmin; Sai, Hiroaki; Wiesner, Ulich; Kim, Jin Kon; Lee, Jinwoo

    2011-02-22

    A "one-pot" synthetic method was developed to produce L1(0)-phase FePt nanoparticles in ordered mesostructured aluminosilicate/carbon composites using polyisoprene-block-poly(ethylene oxide) (PI-b-PEO) as a structure-directing agent. PI-b-PEO block copolymers with aluminosilicate sols are self-assembled with a hydrophobic iron precursor (dimethylaminomethyl-ferrocene) and a hydrophobic platinum precursor (dimethyl(1,5-cyclooctadiene)platinum(II)) to obtain mesostructured composites. The as-synthesized material was heat-treated to 800 °C under an Ar/H(2) mixture (5% v/v), resulting in the formation of fct FePt nanocrystals encapsulated in ordered mesopores. By changing the quantities of the Fe and Pt precursors in the composite materials, the average particle size of the resulting fct FePt, estimated using the Debye-Scherer equation with X-ray diffraction patterns, can be easily controlled to be 2.6-10.4 nm. Using this simple synthetic method, we can extend the size of directly synthesized fct FePt up to ∼10 nm, which cannot be achieved directly in the colloidal synthetic method. All fct FePt nanoparticles show hysteresis behavior at room temperature, which indicates that ferromagnetic particles are obtained inside mesostructued channels. Well-isolated, ∼10 nm fct FePt have a coercivity of 1100 Oe at 300 K. This coercivity value is higher than values of fct FePt nanoparticles synthesized through the tedious hard template method by employing SBA-15 as a host material. The coercivity value for FePt-1 (2.6 nm) at 5 K is as high as 11 900 Oe, which is one of the largest values reported for FePt nanoparticles, or any other magnetic nanoparticles. The fct FePt nanoparticles also showed exchange-bias behavior.

  16. Transport and Depositional Model for Large Country Rock Blocks Within the Searchlight Pluton, Southern Nevada

    NASA Astrophysics Data System (ADS)

    Perrault, D. S.; Furbish, D. J.; Miller, C. F.

    2006-05-01

    Searchlight pluton, a steeply tilted, 10 km thick Miocene intrusion in the Colorado River Extensional Corridor, exposes a zone with abundant, 5-400 m long blocks of Proterozoic gneiss. Blocks are present within a pair of subparallel horizons that make up a 2 km-thick zone and extend about 6 km laterally away from the pluton's north margin slightly oblique to the initially subhorizontal boundary between the pluton's middle unit (granite) and lower unit (qtz monzonite). Blocks are a variety of Precambrian metasedimentary gneisses, granitic gneisses, and mylonites. Blocks are commonly polylithologic and well foliated, with long and intermediate dimensions parallel to both their own foliation and that of the granitic host. Their average aspect ratio is ~ 4:1. Blocks within these horizons are interpreted as stoped (detached country rock that experience gravity- induced displacement) based on several lines of evidence. First, the distribution and abundances of blocks are not consistent with an isolated panel of wall rock (screen). The zone is laterally discontinuous (local abundances vary from ~ 0-40 %); transects a gradational (cm-m scale) internal contact at a slightly oblique angle; and tapers away from the pluton's margin. Second, while block foliations are homoclinal and show fairly consistent attitudes from block to block, block foliations are discordant with wall rock foliations at the same stratigraphic level (adjacent north wall). Third, mush disturbance features such as schlieren and enhanced feldspar foliation beneath blocks suggest a downward compaction. We interpret the blocks to have been emplaced after wall collapse events. We are using scaled settling experiments to clarify how blocks move within viscous fluids and interact with crystal mushes. The experiments, involving tabular ceramic blocks with density ρ = 1.75-2.20 g cm-3 settling in shampoo (ρ = 1.02 g cm-3) with viscosity μ = 20.35 Pa s, are scaled to order-of-magnitude by the particle Reynolds

  17. Modified round block mastopexy versus traditional round block mastopexy.

    PubMed

    Sterodimas, A; Nicaretta, B; Boriani, F

    2015-01-01

    Breast ptosis may be caused by several factors, including significant weight loss, pregnancy, long breastfeeding periods, and involution of the postmenopausal breast tissue. The authors performed a prospective study to evaluate patient satisfaction and the rate of complications after modified round block mastopexy versus traditional round block mastopexy. Forty-four patients fulfilled the inclusion criteria for undergoing round block mastopexy in a prospective randomized controlled study performed from 2007 to 2008. All the patients received polyurethane silicone implants. Group A included patients who underwent the traditional round block technique described by Benelli. Group B included patients who underwent the traditional round block and 4 cardinal glando-glandular permanent sutures. The overall satisfaction with body appearance after breast mastopexy was rated on a scale of 1 (poor), 2 (fair), 3 (good), 4 (very good), and 5 (excellent). Group A patient ages ranged from 28 to 52 years and in Group B ranged from 29 to 49 years. The mean implant volume was 215 cc in both Groups. The complication and satisfaction rates for both Groups are reported. The combination of the cardinal glandulo-glandular sutures along with the traditional round block appears to be key to preventing the areolar enlargement and persistent breast ptosis. The satisfaction rates in patients who underwent the modified round mastopexy appear superior when compared to the traditional round block mastopexy. Furhter long-term follow-up need to be performed in order to confirm the favorable results seen in this series of cases.

  18. Block copolymer adhesion promoters via ring-opening metathesis polymerization

    DOEpatents

    Kent, Michael S.; Saunders, Randall

    1997-01-01

    Coupling agents based on functionalized block copolymers for bonding thermoset polymers to solid materials. These are polymers which possess at least two types of functional groups, one which is able to attach to and react with solid surfaces, and another which can react with a thermoset resin, which are incorporated as pendant groups in monomers distributed in blocks (typically two) along the backbone of the chain. The block copolymers in this invention are synthesized by living ring-opening metathesis polymerization.

  19. Performance and microbial community composition dynamics of aerobic granular sludge from sequencing batch bubble column reactors operated at 20 degrees C, 30 degrees C, and 35 degrees C.

    PubMed

    Ebrahimi, Sirous; Gabus, Sébastien; Rohrbach-Brandt, Emmanuelle; Hosseini, Maryam; Rossi, Pierre; Maillard, Julien; Holliger, Christof

    2010-07-01

    Two bubble column sequencing batch reactors fed with an artificial wastewater were operated at 20 degrees C, 30 degrees C, and 35 degrees C. In a first stage, stable granules were obtained at 20 degrees C, whereas fluffy structures were observed at 30 degrees C. Molecular analysis revealed high abundance of the operational taxonomic unit 208 (OTU 208) affiliating with filamentous bacteria Leptothrix spp. at 30 degrees C, an OTU much less abundant at 20 degrees C. The granular sludge obtained at 20 degrees C was used for the second stage during which one reactor was maintained at 20 degrees C and the second operated at 30 degrees C and 35 degrees C after prior gradual increase of temperature. Aerobic granular sludge with similar physical properties developed in both reactors but it had different nutrient elimination performances and microbial communities. At 20 degrees C, acetate was consumed during anaerobic feeding, and biological phosphorous removal was observed when Rhodocyclaceae-affiliating OTU 214 was present. At 30 degrees C and 35 degrees C, acetate was mainly consumed during aeration and phosphorous removal was insignificant. OTU 214 was almost absent but the Gammaproteobacteria-affiliating OTU 239 was more abundant than at 20 degrees C. Aerobic granular sludge at all temperatures contained abundantly the OTUs 224 and 289 affiliating with Sphingomonadaceae indicating that this bacterial family played an important role in maintaining stable granular structures.

  20. Facile synthesis of main-chain degradable block copolymers for performance enhanced dismantlable adhesion.

    PubMed

    Sato, Eriko; Hagihara, Takashi; Matsumoto, Akikazu

    2012-04-01

    Block copolymers consisting of readily degradable polyperoxides and non-degradable vinyl polymers as the block segments were successfully synthesized by reversible chain transfer catalyzed polymerization, which is one of living radical polymerization techniques. The block copolymers showed characteristic morphology and wettability being different from the polymer blends. When block copolymers containing polyperoxide and polymethacrylate blocks were heated below 150 °C, the polyperoxide blocks were completely degraded and the polymethacrylate blocks were recovered without degradation. Block copolymers containing a poly(2-ethylhexyl methacrylate) block were then investigated as a dismantlable adhesion material, which requires adequate bonding strength during use and easy debonding on demand. Among the several block copolymers, the one consisting of poly(2-ethylhexyl methacrylate) and polyperoxide from methyl sorbate (PPMS) (M(n) = 4900) exhibited good performance as a pressure-sensitive adhesive (PSA). After heating the test specimens in a temperature range from 60 to 100 °C, PSA performance, which was evaluated by 180° peel strength and shear holding power measurements, was significantly diminished. Especially, after heating at 100 °C for 1 h, spontaneous debonding of some test specimens was observed because of the evolution of volatile acetaldehyde from PPMS.

  1. Fabrication of carbonate apatite block based on internal dissolution-precipitation reaction of dicalcium phosphate and calcium carbonate.

    PubMed

    Daitou, Fumikazu; Maruta, Michito; Kawachi, Giichiro; Tsuru, Kanji; Matsuya, Shigeki; Terada, Yoshihiro; Ishikawa, Kunio

    2010-05-01

    In this study, we investigated a novel method for fabrication of carbonate apatite block without ionic movement between precursor and solution by using precursor that includes all constituent ions of carbonate apatite. A powder mixture prepared from dicalcium phosphate anhydrous and calcite at appropriate Ca/P ratios (1.5, 1.67, and 1.8) was used as starting material. For preparation of specimens, the slurry made from the powder mixture and distilled water was packed in a split stainless steel mold and heat - treated, ranging from 60 degrees C to 100 degrees C up to 48 hours at 100% humidity. It appeared that carbonate apatite could be obtained above 70 degrees C and monophasic carbonate apatite could be obtained from the powder mixture at Ca/P ratio of 1.67. Carbonate content of the specimen was about 5-7%. Diametral tensile strength of the carbonate apatite blocks slightly decreased with increasing treatment temperature. The decrease in diametral tensile strength is thought to be related to the crystal size of the carbonate apatite formed.

  2. Plastic Fibre Reinforced Soil Blocks as a Sustainable Building Material

    NASA Astrophysics Data System (ADS)

    Prasad, C. K. Subramania; Nambiar, E. K. Kunhanandan; Abraham, Benny Mathews

    2012-10-01

    Solid waste management, especially the huge quantity of waste plastics, is one of the major environmental concerns nowadays. Their employability in block making in the form of fibres, as one of the methods of waste management, can be investigated through a fundamental research. This paper highlights the salient observations from a systematic investigation on the effect of embedded fibre from plastic waste on the performance of stabilised mud blocks. Stabilisation of the soil was done by adding cement, lime and their combination. Plastic fibre in chopped form from carry bags and mineral water bottles were added (0.1% & 0.2% by weight of soil) as reinforcement. The blocks were tested for density, and compressive strength, and observed failure patterns were analysed. Blocks with 0.1% of plastic fibres showed an increase in strength of about 3 to 10%. From the observations of failure pattern it can be concluded that benefits of fibre reinforcement includes both improved ductility in comparison with raw blocks and inhibition of crack propogation after its initial formation.

  3. Automation of block assignment planning using a diagram-based scenario modeling method

    NASA Astrophysics Data System (ADS)

    Hwang, In Hyuck; Kim, Youngmin; Lee, Dong Kun; Shin, Jong Gye

    2014-03-01

    Most shipbuilding scheduling research so far has focused on the load level on the dock plan. This is be¬cause the dock is the least extendable resource in shipyards, and its overloading is difficult to resolve. However, once dock scheduling is completed, making a plan that makes the best use of the rest of the resources in the shipyard to minimize any additional cost is also important. Block assignment planning is one of the midterm planning tasks; it assigns a block to the facility (factory/shop or surface plate) that will actually manufacture the block according to the block characteristics and current situation of the facility. It is one of the most heavily loaded midterm planning tasks and is carried out manu¬ally by experienced workers. In this study, a method of representing the block assignment rules using a diagram was su¬ggested through analysis of the existing manual process. A block allocation program was developed which automated the block assignment process according to the rules represented by the diagram. The planning scenario was validated through a case study that compared the manual assignment and two automated block assignment results.

  4. Neutronic reactor

    DOEpatents

    Lewis, Warren R.

    1978-05-30

    A graphite-moderated, water-cooled nuclear reactor including a plurality of rectangular graphite blocks stacked in abutting relationship in layers, alternate layers having axes which are normal to one another, alternate rows of blocks in alternate layers being provided with a channel extending through the blocks, said channeled blocks being provided with concave sides and having smaller vertical dimensions than adjacent blocks in the same layer, there being nuclear fuel in the channels.

  5. Preschoolers' Thinking during Block Play

    ERIC Educational Resources Information Center

    Piccolo, Diana L.; Test, Joan

    2010-01-01

    Children build foundations for mathematical thinking in early play and exploration. During the preschool years, children enjoy exploring mathematical concepts--such as patterns, shape, spatial relationships, and measurement--leading them to spontaneously engage in mathematical thinking during play. Block play is one common example that engages…

  6. [A case of severe bradycardia and AV block during administration of propofol].

    PubMed

    Takase, Hajime; Kudoh, Akira; Takazawa, Tomoko

    2003-09-01

    A 69-yr-old man underwent emergency laparotomy. He was in endotoxic shock. Preoperative evaluation including a full blood count, chest X-ray and ECG were normal. Body temperature was 37.4 degrees C. Preoperative arterial pressure was 140/80 mmHg and heart rate 65 bpm. Anesthesia was induced with ketamine 100 mg, propofol 20 mg, fentanyl 50 micrograms and vecuronium 4 mg and maintained with propofol 4 mg.kg-1.hr-1 and fentanyl. Soon after opening the abdominal peritoneum, severe bradycardia (< 20 bpm) occurred, but it was effectively treated by ephedrine 16 mg. After that, surgery was performed uneventfully. In the intensive care unit (ICU), the patient developed four episodes of severe atrioventricular (AV) block after stimulation of the trachea by suction drainage under sedation with propofol, although there was no AV block during sedation with ketamine and propofol. After stopping propofol, the AV block was no longer observed. He was discharged from the ICU on the 12th postoperative day. Postoperative Holter ECG and echocardiography showed no abnormalities. It is likely that stimulation of the trachea triggered vagovagal reflex and propofol prolonged AV conduction, causing the AV block.

  7. Frequency stability of on-orbit GPS Block-I and Block-II Navstar clocks

    NASA Astrophysics Data System (ADS)

    McCaskill, Thomas B.; Reid, Wilson G.; Buisson, James A.

    On-orbit analysis of the Global Positioning System (GPS) Block-I and Block-II Navstar clocks has been performed by the Naval Research Laboratory using a multi-year database. The Navstar clock phase-offset measurements were computed from pseudorange measurements made by the five GPS monitor sites and from the U.S. Naval Observatory precise-time site using single or dual frequency GPS receivers. Orbital data was obtained from the Navstar broadcast ephemeris and from the best-fit, postprocessed orbital ephemerides supplied by the Naval Surface Weapons Center or by the Defense Mapping Agency. Clock performance in the time domain is characterized using frequency-stability profiles with sample times that vary from 1 to 100 days. Composite plots of Navstar frequency stability and time-prediction uncertainty are included as a summary of clock analysis results. The analysis includes plots of the clock phase offset and frequency offset histories with the eclipse seasons superimposed on selected plots to demonstrate the temperature sensitivity of one of the Block-I Navstar rubidium clocks. The potential impact on navigation and on transferring precise time of the degradation in the long-term frequency stability of the rubidium clocks is discussed.

  8. The relationship between mean anomaly block sizes and spherical harmonic representations. [of earth gravity

    NASA Technical Reports Server (NTRS)

    Rapp, R. H.

    1977-01-01

    The frequently used rule specifying the relationship between a mean gravity anomaly in a block whose side length is theta degrees and a spherical harmonic representation of these data to degree l-bar is examined in light of the smoothing parameter used by Pellinen (1966). It is found that if the smoothing parameter is not considered, mean anomalies computed from potential coefficients can be in error by about 30% of the rms anomaly value. It is suggested that the above mentioned rule should be considered only a crude approximation.

  9. Virtual displays for 360-degree video

    NASA Astrophysics Data System (ADS)

    Gilbert, Stephen; Boonsuk, Wutthigrai; Kelly, Jonathan W.

    2012-03-01

    In this paper we describe a novel approach for comparing users' spatial cognition when using different depictions of 360- degree video on a traditional 2D display. By using virtual cameras within a game engine and texture mapping of these camera feeds to an arbitrary shape, we were able to offer users a 360-degree interface composed of four 90-degree views, two 180-degree views, or one 360-degree view of the same interactive environment. An example experiment is described using these interfaces. This technique for creating alternative displays of wide-angle video facilitates the exploration of how compressed or fish-eye distortions affect spatial perception of the environment and can benefit the creation of interfaces for surveillance and remote system teleoperation.

  10. Developmental tumors and adjacent cortical dysplasia: single or dual pathology?

    PubMed

    Palmini, André; Paglioli, Eliseu; Silva, Vinicius Duval

    2013-12-01

    Developmental tumors often lead to refractory partial seizures and constitute a well-defined, surgically remediable epilepsy syndrome. Dysplastic features are often associated with these tumors, and their significance carries both practical and conceptual relevance. If associated focal cortical dysplasia (FCD) relates to the extent of the epileptogenic tissue, then presurgical evaluation and surgical strategies should target both the tumor and the surrounding dyslaminated cortex. Furthermore, the association has been included in the recently revised classification of FCD and the epileptogenicity of this associated dysplastic tissue is crucial to validate such revision. In addition to the possibility of representing dual pathology, the association of developmental tumors and adjacent dysplasia may instead represent a single developmental lesion with distinct parts distributed along a histopathologic continuum. Moreover, the possibility that this adjacent dyslamination is of minor epileptogenic relevance should also be entertained. Surgical data show that complete resection of the solid tumors and immediately adjacent tissue harboring satellites may disrupt epileptogenic networks and lead to high rates of seizure freedom, challenging the epileptogenic relevance of more extensive adjacent dyslaminated cortex. Whether the latter is a primary or secondary abnormality and whether dyslaminated cortex in the context of a second lesion may produce seizures after complete resection of the main lesion is still to be proven. Wiley Periodicals, Inc. © 2013 International League Against Epilepsy.

  11. Characterization of compressed earth blocks using low frequency guided acoustic waves.

    PubMed

    Ben Mansour, Mohamed; Ogam, Erick; Fellah, Z E A; Soukaina Cherif, Amel; Jelidi, Ahmed; Ben Jabrallah, Sadok

    2016-05-01

    The objective of this work was to analyze the influence of compaction pressure on the intrinsic acoustic parameters (porosity, tortuosity, air-flow resistivity, viscous, and thermal characteristic lengths) of compressed earth blocks through their identification by solving an inverse acoustic wave transmission problem. A low frequency acoustic pipe (60-6000 Hz of length 22 m, internal diameter 3.4 cm) was used for the experimental characterization of the samples. The parameters were identified by the minimization of the difference between the transmissions coefficients data obtained in the pipe with that from an analytical interaction model in which the compressed earth blocks were considered as having rigid frames. The viscous and thermal effects in the pores were accounted for by employing the Johnson-Champoux-Allard-Lafarge model. The results obtained by inversion for high-density compressed earth blocks showed some discordance between the model and experiment especially for the high frequency limit of the acoustic characteristics studied. This was as a consequence of applying high compaction pressure rendering them very highly resistive therefore degrading the signal-to-noise ratios of the transmitted waves. The results showed that the airflow resistivity was very sensitive to the degree of the applied compaction pressure used to form the blocks.

  12. 76 FR 65562 - Unblocking of One Specially Designated National or Blocked Person Pursuant to Executive Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... Executive Order 13350 of July 30, 2004. DATES: The removal of this entity from the SDN List is effective as...-2490. SUPPLENTARY IMFORMATION: Electronic and Facsimile Availability The SDN List and additional... blocked pursuant to Executive Order 13315, as amended, should be removed from the SDN List. The following...

  13. 76 FR 60129 - Unblocking of One Specially Designated National or Blocked Person Pursuant to Executive Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Executive Order 13350 of July 30, 2004. DATES: The removal of this individual from the SDN List is effective...-2490. SUPPLEMENTARY INFORMATION: Electronic and Facsimile Availability The SDN List and additional... blocked pursuant to Executive Order 13315, as amended, should be removed from the SDN List. The following...

  14. Effects of Cocos Ridge Collision on the Western Caribbean: Is there a Panama Block?

    NASA Astrophysics Data System (ADS)

    Kobayashi, D.; La Femina, P. C.; Geirsson, H.; Chichaco, E.; Abrego M, A. A.; Fisher, D. M.; Camacho, E. I.

    2011-12-01

    earthquake relocation and geologic data are used to define block boundaries and fault geometries. We invert the three-dimensional GPS velocity vectors and earthquake slip vectors to estimate the magnitude and spatial distribution of interplate mechanical coupling on active plate and block boundaries around the Panama block; the Middle America Trench - South Panama Deformed Belt, the Central Costa Rican Deformed Belt, and the North Panama Deformed Belt in particular, and the rates of relative plate motion between the Panama block and the adjacent Cocos, Nazca, and Caribbean plates. This study tests whether the Panama block responds to the ridge collision as a rigid tectonic block or as a deforming zone consisting of multiple blocks.

  15. Block copolymer adhesion promoters via ring-opening metathesis polymerization

    DOEpatents

    Kent, M.S.; Saunders, R.

    1997-02-18

    Coupling agents are disclosed based on functionalized block copolymers for bonding thermoset polymers to solid materials. These are polymers which possess at least two types of functional groups, one which is able to attach to and react with solid surfaces, and another which can react with a thermoset resin, which are incorporated as pendant groups in monomers distributed in blocks (typically two) along the backbone of the chain. The block copolymers in this invention are synthesized by living ring-opening metathesis polymerization. 18 figs.

  16. Blocking Losses With a Photon Counter

    NASA Technical Reports Server (NTRS)

    Moision, Burce E.; Piazzolla, Sabino

    2012-01-01

    It was not known how to assess accurately losses in a communications link due to photodetector blocking, a phenomenon wherein a detector is rendered inactive for a short time after the detection of a photon. When used to detect a communications signal, blocking leads to losses relative to an ideal detector, which may be measured as a reduction in the communications rate for a given received signal power, or an increase in the signal power required to support the same communications rate. This work involved characterizing blocking losses for single detectors and arrays of detectors. Blocking may be mitigated by spreading the signal intensity over an array of detectors, reducing the count rate on any one detector. A simple approximation was made to the blocking loss as a function of the probability that a detector is unblocked at a given time, essentially treating the blocking probability as a scaling of the detection efficiency. An exact statistical characterization was derived for a single detector, and an approximation for multiple detectors. This allowed derivation of several accurate approximations to the loss. Methods were also derived to account for a rise time in recovery, and non-uniform illumination due to diffraction and atmospheric distortion of the phase front. It was assumed that the communications signal is intensity modulated and received by an array of photon-counting photodetectors. For the purpose of this analysis, it was assumed that the detectors are ideal, in that they produce a signal that allows one to reproduce the arrival times of electrons, produced either as photoelectrons or from dark noise, exactly. For single detectors, the performance of the maximum-likelihood (ML) receiver in blocking is illustrated, as well as a maximum-count (MC) receiver, that, when receiving a pulse-position-modulated (PPM) signal, selects the symbol corresponding to the slot with the largest electron count. Whereas the MC receiver saturates at high count rates

  17. Shaking table experimentation on adjacent structures controlled by passive and semi-active MR dampers

    NASA Astrophysics Data System (ADS)

    Basili, M.; De Angelis, M.; Fraraccio, G.

    2013-06-01

    This paper presents the results of shaking table tests on adjacent structures controlled by passive and semi-active MR dampers. The aim was to demonstrate experimentally the effectiveness of passive and semi-active strategies in reducing structural vibrations due to seismic excitation. The physical model at issue was represented by two adjacent steel structures, respectively of 4 and 2 levels, connected at the second level by a MR damper. When the device operated in semi-active mode, an ON-OFF control algorithm, derived by the Lyapunov stability theory, was implemented and experimentally validated. Since the experimentation concerned adjacent structures, two control objectives have been reached: global and selective protection. In case of global protection, the attention was focused on protecting both structures, whereas, in case of selective protection, the attention was focused on protecting only one structure. For each objective the effectiveness of passive control has been compared with the situation of no control and then the effectiveness of semi-active control has been compared with the passive one. The quantities directly compared have been: measured displacements, accelerations and force-displacement of the MR damper, moreover some global response quantities have been estimated from experimental measures, which are the base share force and the base bending moment, the input energy and the energy dissipated by the device. In order to evaluate the effectiveness of the control action in both passive and semi-active case, an energy index EDI, previously defined and already often applied numerically, has been utilized. The aspects investigated in the experimentation have been: the implementation and validation of the control algorithm for selective and global protection, the MR damper input voltage influence, the kind of seismic input and its intensity.

  18. Trends in Undergraduate Economics Degrees, 1991-2012

    ERIC Educational Resources Information Center

    Siegfried, John J.

    2013-01-01

    The 2007-10 growth spurt (18 percent over three years) in U.S. undergraduate economics degrees came to an abrupt end in 2011 and 2012. Degrees awarded grew less than one percent over the past two years.

  19. Inverse Relationship Between Membranous Septal Length and the Risk of Atrioventricular Block in Patients Undergoing Transcatheter Aortic Valve Implantation.

    PubMed

    Hamdan, Ashraf; Guetta, Victor; Klempfner, Robert; Konen, Eli; Raanani, Ehud; Glikson, Michael; Goitein, Orly; Segev, Amit; Barbash, Israel; Fefer, Paul; Spiegelstein, Dan; Goldenberg, Ilan; Schwammenthal, Ehud

    2015-08-17

    This study sought to examine whether imaging of the atrioventricular (AV) membranous septum (MS) by computed tomography (CT) can be used to identify patient-specific anatomic risk of high-degree AV block and permanent pacemaker (PPM) implantation before transcatheter aortic valve implantation (TAVI) with self-expandable valves. MS length represents an anatomic surrogate of the distance between the aortic annulus and the bundle of His and may therefore be inversely related to the risk of conduction system abnormalities after TAVI. Seventy-three consecutive patients with severe aortic stenosis underwent contrast-enhanced CT before TAVI. The aortic annulus, aortic valve, and AV junction were assessed, and MS length was measured in the coronal view. In 13 patients (18%), high-degree AV block developed, and 21 patients (29%) received a PPM. Multivariable logistic regression analysis revealed MS length as the most powerful pre-procedural independent predictor of high-degree AV block (odds ratio [OR]: 1.35, 95% confidence interval [CI]: 1.1 to 1.7, p = 0.01) and PPM implantation (OR: 1.43, 95% CI: 1.1 to 1.8, p = 0.002). When taking into account pre- and post-procedural parameters, the difference between MS length and implantation depth emerged as the most powerful independent predictor of high-degree AV block (OR: 1.4, 95% CI: 1.2 to 1.7, p < 0.001), whereas the difference between MS length and implantation depth and calcification in the basal septum were the most powerful independent predictors of PPM implantation (OR: 1.39, 95% CI: 1.2 to 1.7, p < 0.001 and OR: 4.9, 95% CI: 1.2 to 20.5, p = 0.03; respectively). Short MS, insufficient difference between MS length and implantation depth, and the presence of calcification in the basal septum, factors that may all facilitate mechanical compression of the conduction tissue by the implanted valve, predict conduction abnormalities after TAVI with self-expandable valves. CT assessment of membranous septal anatomy provides

  20. Discoloration of various CAD/CAM blocks after immersion in coffee.

    PubMed

    Lauvahutanon, Sasipin; Shiozawa, Maho; Takahashi, Hidekazu; Iwasaki, Naohiko; Oki, Meiko; Finger, Werner J; Arksornnukit, Mansuang

    2017-02-01

    This study evaluated color differences (Δ E s) and translucency parameter changes (Δ TP s) of various computer-aided design/computer-aided manufacturing (CAD/CAM) blocks after immersion in coffee. Eight CAD/CAM blocks and four restorative composite resins were evaluated. The CIE L * a * b * values of 2.0 mm thick disk-shaped specimens were measured using the spectrophotometer on white and black backgrounds ( n = 6). The Δ E s and Δ TP s of one day, one week, and one month immersion in coffee or water were calculated. The values of each material were analyzed by two-way ANOVA and Tukey's multiple comparisons (α = 0.05). The Δ E s after prophylaxis paste polishing of 1 month coffee immersion specimens, water sorption and solubility were also evaluated. After one month in coffee, Δ E s of CAD/CAM composite resin blocks and restorative composites ranged from 1.6 to 3.7 and from 2.1 to 7.9, respectively, and Δ TP s decreased. The ANOVA of Δ E s and Δ TP s revealed significant differences in two main factors, immersion periods and media, and their interaction except for Δ E s of TEL (Telio CAD, Ivoclar Vivadent). The Δ E s significantly decreased after prophylaxis polishing except GRA (Gradia Block, GC). There was no significant correlation between Δ E s and water sorption or solubility in water. The Δ E s of CAD/CAM blocks after immersion in coffee varied among products and were comparable to those of restorative composite resins. The discoloration of CAD/CAM composite resin blocks could be effectively removed with prophylaxis paste polishing, while that of some restorative composites could not be removed.

  1. 31 CFR 594.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 594.301 Section 594.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS...

  2. 31 CFR 545.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 545.301 Section 545.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TALIBAN (AFGHANISTAN) SANCTIONS...

  3. 31 CFR 551.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 551.301 Section 551.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY SOMALIA SANCTIONS REGULATIONS...

  4. 77 FR 2777 - Unblocking of One Specially Designated National or Blocked Person Pursuant to Executive Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ...,'' as amended by Executive Order 13350 of July 30, 2004. DATES: The removal of this entity from the SDN... The SDN List and additional information concerning OFAC are available from OFAC's web site ( www... property were blocked pursuant to Executive Order 13315, as amended, should be removed from the SDN List...

  5. Random and Block Sulfonated Polyaramides as Advanced Proton Exchange Membranes

    DOE PAGES

    Kinsinger, Corey L.; Liu, Yuan; Liu, Feilong; ...

    2015-10-09

    We present here the experimental and computational characterization of two novel copolyaramide proton exchange membranes (PEMs) with higher conductivity than Nafion at relatively high temperatures, good mechanical properties, high thermal stability, and the capability to operate in low humidity conditions. The random and block copolyaramide PEMs are found to possess different ion exchange capacities (IEC) in addition to subtle structural and morphological differences, which impact the stability and conductivity of the membranes. SAXS patterns indicate the ionomer peak for the dry block copolymer resides at q = 0.1 Å –1, which increases in amplitude when initially hydrated to 25% relativemore » humidity, but then decrease in amplitude with additional hydration. This pattern is hypothesized to signal the transport of water into the polymer matrix resulting in a reduced degree of phase separation. Coupled to these morphological changes, the enhanced proton transport characteristics and structural/mechanical stability for the block copolymer are hypothesized to be primarily due to the ordered structure of ionic clusters that create connected proton transport pathways while reducing swelling upon hydration. Interestingly, the random copolymer did not possess an ionomer peak at any of the hydration levels investigated, indicating a lack of any significant ionomer structure. The random copolymer also demonstrated higher proton conductivity than the block copolymer, which is opposite to the trend normally seen in polymer membranes. However, it has reduced structural/mechanical stability as compared to the block copolymer. In conclusion, this reduction in stability is due to the random morphology formed by entanglements of polymer chains and the adverse swelling characteristics upon hydration. Therefore, the block copolymer with its enhanced proton conductivity characteristics, as compared to Nafion, and favorable structural/mechanical stability, as compared to the

  6. Slip-spring model of entangled rod-coil block copolymers

    NASA Astrophysics Data System (ADS)

    Wang, Muzhou; Likhtman, Alexei E.; Olsen, Bradley D.

    2015-03-01

    Understanding the dynamics of rod-coil block copolymers is important for optimal design of functional nanostructured materials for organic electronics and biomaterials. Recently, we proposed a reptation theory of entangled rod-coil block copolymers, predicting the relaxation mechanisms of activated reptation and arm retraction that slow rod-coil dynamics relative to coil and rod homopolymers, respectively. In this work, we introduce a coarse-grained slip-spring model of rod-coil block copolymers to further explore these mechanisms. First, parameters of the coarse-grained model are tuned to match previous molecular dynamics simulation results for coils, rods, and block copolymers. For activated reptation, rod-coil copolymers are shown to disfavor configurations where the rod occupies curved portions of the entanglement tube of randomly varying curvature created by the coil ends. The effect of these barriers on diffusion is quantitatively captured by considering one-dimensional motion along an entanglement tube with a rough free energy potential. Finally, we analyze the crossover between the two mechanisms. The resulting dynamics from both mechanisms acting in combination is faster than from each one individually.

  7. Molecular Mobility in Phase Segregated Bottlebrush Block Copolymer Melts

    NASA Astrophysics Data System (ADS)

    Yavitt, Benjamin; Gai, Yue; Song, Dongpo; Winter, H. Henning; Watkins, James

    We investigate the linear viscoelastic behavior of poly(styrene)-block-poly(ethylene oxide) (PS-b-PEO) brush block copolymer (BBCP) materials over a range of vol. fractions and with side chain lengths below the entanglement molecular weights. The high chain mobility of the brush architecture results in rapid micro-phase segregation of the brush copolymer segments, which occurs during thermal annealing at mild temperatures. Master curves of the dynamic moduli were obtained by time-temperature superposition. The reduced degree of chain entanglements leads to a unique liquid-like rheology similar to that of bottlebrush homopolymers, even in the phase segregated state. We also explore the alignment of phase segregated domains at exceptionally low strain amplitudes (γ = 0.01) and mild processing temperatures using small angle X-ray scattering (SAXS). Domain orientation occurred readily at strains within the linear viscoelastic regime without noticeable effect on the moduli. This interplay of high molecular mobility and rapid phase segregation that are exhibited simultaneously in BBCPs is in contrast to the behavior of conventional linear block copolymer (LBCP) analogs and opens up new possibilities for processing BBCP materials for a wide range of nanotechnology applications. NSF Center for Hierarchical Manufacturing at the University of Massachusetts, Amherst (CMMI-1025020).

  8. Epidemic spreading on preferred degree adaptive networks.

    PubMed

    Jolad, Shivakumar; Liu, Wenjia; Schmittmann, B; Zia, R K P

    2012-01-01

    We study the standard SIS model of epidemic spreading on networks where individuals have a fluctuating number of connections around a preferred degree κ. Using very simple rules for forming such preferred degree networks, we find some unusual statistical properties not found in familiar Erdös-Rényi or scale free networks. By letting κ depend on the fraction of infected individuals, we model the behavioral changes in response to how the extent of the epidemic is perceived. In our models, the behavioral adaptations can be either 'blind' or 'selective'--depending on whether a node adapts by cutting or adding links to randomly chosen partners or selectively, based on the state of the partner. For a frozen preferred network, we find that the infection threshold follows the heterogeneous mean field result λ(c)/μ = <κ>/<κ2> and the phase diagram matches the predictions of the annealed adjacency matrix (AAM) approach. With 'blind' adaptations, although the epidemic threshold remains unchanged, the infection level is substantially affected, depending on the details of the adaptation. The 'selective' adaptive SIS models are most interesting. Both the threshold and the level of infection changes, controlled not only by how the adaptations are implemented but also how often the nodes cut/add links (compared to the time scales of the epidemic spreading). A simple mean field theory is presented for the selective adaptations which capture the qualitative and some of the quantitative features of the infection phase diagram.

  9. 31 CFR 594.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Blocked account; blocked property. 594.301 Section 594.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS...

  10. 31 CFR 594.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Blocked account; blocked property. 594.301 Section 594.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS...

  11. 31 CFR 594.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Blocked account; blocked property. 594.301 Section 594.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS...

  12. 31 CFR 546.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 546.302 Section 546.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DARFUR SANCTIONS REGULATIONS General...

  13. 31 CFR 593.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 593.301 Section 593.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES...

  14. 31 CFR 510.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Blocked account; blocked property. 510.301 Section 510.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY NORTH KOREA SANCTIONS REGULATIONS General...

  15. 31 CFR 547.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Blocked account; blocked property. 547.302 Section 547.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO...

  16. Solvothermal Vapor Annealing of Lamellar Poly(styrene)-block-poly(d,l-lactide) Block Copolymer Thin Films for Directed Self-Assembly Application.

    PubMed

    Cummins, Cian; Mokarian-Tabari, Parvaneh; Andreazza, Pascal; Sinturel, Christophe; Morris, Michael A

    2016-03-01

    Solvothermal vapor annealing (STVA) was employed to induce microphase separation in a lamellar forming block copolymer (BCP) thin film containing a readily degradable block. Directed self-assembly of poly(styrene)-block-poly(d,l-lactide) (PS-b-PLA) BCP films using topographically patterned silicon nitride was demonstrated with alignment over macroscopic areas. Interestingly, we observed lamellar patterns aligned parallel as well as perpendicular (perpendicular microdomains to substrate in both cases) to the topography of the graphoepitaxial guiding patterns. PS-b-PLA BCP microphase separated with a high degree of order in an atmosphere of tetrahydrofuran (THF) at an elevated vapor pressure (at approximately 40-60 °C). Grazing incidence small-angle X-ray scattering (GISAXS) measurements of PS-b-PLA films reveal the through-film uniformity of perpendicular microdomains after STVA. Perpendicular lamellar orientation was observed on both hydrophilic and relatively hydrophobic surfaces with a domain spacing (L0) of ∼32.5 nm. The rapid removal of the PLA microdomains is demonstrated using a mild basic solution for the development of a well-defined PS mask template. GISAXS data reveal the through-film uniformity is retained following wet etching. The experimental results in this article demonstrate highly oriented PS-b-PLA microdomains after a short annealing period and facile PLA removal to form porous on-chip etch masks for nanolithography application.

  17. Community conservation adjacent to Ruaha National Park, Tanzania

    Treesearch

    Sue Stolberger

    2007-01-01

    In the areas adjacent to Ruaha National Park where rural communities exist, much more work and education is required to enable them to benefit directly and indirectly from tourism and managing their own natural resources.

  18. Use of an Android application “clinometer” for measurement of head down tilt given during subarachnoid block

    PubMed Central

    Dixit, RB; Neema, MM

    2016-01-01

    Context: Head down tilt is given to patients after sub arachnoid block for adjustment of height of block. However, the amount of tilt given is subjective and cannot be documented. Aims: We used an android application named “clinometer” to measure exact degree of tilt given by anesthesiologists as their routine practice. Settings and Design: This observational study, at a medical college hospital, was done in 130 patients given sub arachnoid block for lower abdominal surgeries. Materials and Methods: We observed and documented vital data of patients and measured tilt given by application “clinometer.” Results: We observed that the application was easy to use and measured tilt each time. The result obtained can be documented, digitally saved and transferred. In 130 patients studied, we observed incidence of degree of tilt as follows: 6-8° tilt in 38 patients (29.23%), 8-10 in 36 patients (27.69%), 10-12 in 30 patients (23.08%), 12-14 in 12 patients (9.23%) and 14-16° tilt in 14 patients (10.77%). Use of application was received with enthusiasm by practicing anesthesiologists. Various possible uses of this application are discussed. PMID:26955307

  19. A simple 3-D numerical model of thermal convection in Earth's growing inner core: on the possibility of the formation of the degree-one structure with lateral viscosity variations

    NASA Astrophysics Data System (ADS)

    Yoshida, M.

    2015-12-01

    An east-west hemispherically asymmetric structure for Earth's inner core has been suggested by various seismological evidence, but its origin is not clearly understood. Here, to investigate the possibility of an "endogenic origin" for the degree-one thermal/mechanical structure of the inner core, I performed new numerical simulations of thermal convection in the growing inner core. A setup value that controls the viscosity contrast between the inner core boundary and the interior of the inner core, ΔηT, was taken as a free parameter. Results show that the degree-one structure only appeared for a limited range of ΔηT; such a scenario may be possible but is not considered probable for the real Earth. The degree-one structure may have been realized by an "exogenous factor" due to the planetary-scale thermal coupling among the lower mantle, the outer core, and the inner core, not by an endogenic factor due to the internal rheological heterogeneity.

  20. Hypothermia blocks beta-catenin degradation after focal ischemia in rats.

    PubMed

    Zhang, Hanfeng; Ren, Chuancheng; Gao, Xuwen; Takahashi, Tetsuya; Sapolsky, Robert M; Steinberg, Gary K; Zhao, Heng

    2008-03-10

    Dephosphorylated and activated glycogen synthase kinase (GSK) 3beta hyperphosphorylates beta-catenin, leading to its ubiquitin-proteosome-mediated degradation. beta-catenin-knockdown increases while beta-catenin overexpression prevents neuronal death in vitro; in addition, protein levels of beta-catenin are reduced in the brain of Alzheimer's patients. However, whether beta-catenin degradation is involved in stroke-induced brain injury is unknown. Here we studied activities of GSK 3beta and beta-catenin, and the protective effect of moderate hypothermia (30 degrees C) on these activities after focal ischemia in rats. The results of Western blot showed that GSK 3beta was dephosphorylated at 5 and 24 h after stroke in the normothermic (37 degrees C) brain; hypothermia augmented GSK 3beta dephosphorylation. Because hypothermia reduces infarction, these results contradict with previous studies showing that GSK 3beta dephosphorylation worsens neuronal death. Nevertheless, hypothermia blocked degradation of total GSK 3beta protein. Corresponding to GSK 3beta activity in normothermic rats, beta-catenin phosphorylation transiently increased at 5 h in both the ischemic penumbra and core, and the total protein level of beta-catenin degraded after normothermic stroke. Hypothermia did not inhibit beta-catenin phosphorylation, but it blocked beta-catenin degradation in the ischemic penumbra. In conclusion, moderate hypothermia can stabilize beta-catenin, which may contribute to the protective effect of moderate hypothermia.

  1. Map showing distribution of silver in the nonmagnetic fraction of heavy-mineral concentrates, Richfield 1 degree by 2 degrees Quadrangle, Utah

    USGS Publications Warehouse

    Miller, William R.; Motooka, Jerry M.; McHugh, John B.

    1990-01-01

    This map of the Richfield 1° x 2° quadrangle, Utah, shows the regional distribution of silver in the nonmagnetic fraction of heavy-mineral concentrates of drainage-sediment samples. It is part of a folio of maps of the Richfield 1° x 2° quadrangle, Utah, prepared under the Conterminuous United States Mineral Assessment Program. Other published geochemical maps in this folio are listed in the references (this publication). The Richfield quadrangle is located in west-central Utah and includes the eastern part of the Pioche-Marysvale igneous and mineral belt, which extends from the vicinity of Pioche in southeastern Nevada, east-northeastward for 155 miles into central Utah. The western two-thirds of the Richfield quadrangle is part of the Basin and Range province, whereas the eastern third is part of the High Plateaus of Utah, a subprovince of the Colorado Plateau. Bedrock in the northern part of the Richfield quadrangle consists predominantly of Late Proterozoic and Paleozoic sedimentary strata that were thrust eastward during the Sevier orogeny in Cretaceous time onto an autochthon of Mesozoic sedimentary rocks located in the eastern part of the quadrangle. The southern part of the quadrangle is largely underlain by Oligocene and younger volcanic rocks and related intrusions. Extensional tectonism in late Cenozoic time broke the bedrock terrain into a series of north-trending fault blocks; the uplifted mountain areas were eroded to various degrees and the resulting debris was deposited in adjacent basins. Most of the mineral deposits in the Pioche-Marysvale mineral belt were formed as a result of igneous activity in the middle and late Cenozoic time. A more complete description of the geology and a mineral-resource appraisal of the Richfield quadrangle appears in Steven and Morris (1984 and 1987). The regional sampling program was designed to define broad geochemical patterns and trends that can be utilized along with geological and geophysical data to assess

  2. Concentric network symmetry grasps authors' styles in word adjacency networks

    NASA Astrophysics Data System (ADS)

    Amancio, Diego R.; Silva, Filipi N.; Costa, Luciano da F.

    2015-06-01

    Several characteristics of written texts have been inferred from statistical analysis derived from networked models. Even though many network measurements have been adapted to study textual properties at several levels of complexity, some textual aspects have been disregarded. In this paper, we study the symmetry of word adjacency networks, a well-known representation of text as a graph. A statistical analysis of the symmetry distribution performed in several novels showed that most of the words do not display symmetric patterns of connectivity. More specifically, the merged symmetry displayed a distribution similar to the ubiquitous power-law distribution. Our experiments also revealed that the studied metrics do not correlate with other traditional network measurements, such as the degree or the betweenness centrality. The discriminability power of the symmetry measurements was verified in the authorship attribution task. Interestingly, we found that specific authors prefer particular types of symmetric motifs. As a consequence, the authorship of books could be accurately identified in 82.5% of the cases, in a dataset comprising books written by 8 authors. Because the proposed measurements for text analysis are complementary to the traditional approach, they can be used to improve the characterization of text networks, which might be useful for applications based on stylistic classification.

  3. Quantum bright solitons in a quasi-one-dimensional optical lattice

    NASA Astrophysics Data System (ADS)

    Barbiero, Luca; Salasnich, Luca

    2014-06-01

    We study a quasi-one-dimensional attractive Bose gas confined in an optical lattice with a superimposed harmonic potential by analyzing the one-dimensional Bose-Hubbard Hamiltonian of the system. Starting from the three-dimensional many-body quantum Hamiltonian, we derive strong inequalities involving the transverse degrees of freedom under which the one-dimensional Bose-Hubbard Hamiltonian can be safely used. To have a reliable description of the one-dimensional ground state, which we call a quantum bright soliton, we use the density-matrix-renormalization-group (DMRG) technique. By comparing DMRG results with mean-field (MF) ones, we find that beyond-mean-field effects become relevant by increasing the attraction between bosons or by decreasing the frequency of the harmonic confinement. In particular, we find that, contrary to the MF predictions based on the discrete nonlinear Schrödinger equation, average density profiles of quantum bright solitons are not shape-invariant. We also use the time-evolving-block-decimation method to investigate the dynamical properties of bright solitons when the frequency of the harmonic potential is suddenly increased. This quantum quench induces a breathing mode whose period crucially depends on the final strength of the superimposed harmonic confinement.

  4. Patchy micelles based on coassembly of block copolymer chains and block copolymer brushes on silica particles.

    PubMed

    Zhu, Shuzhe; Li, Zhan-Wei; Zhao, Hanying

    2015-04-14

    Patchy particles are a type of colloidal particles with one or more well-defined patches on the surfaces. The patchy particles with multiple compositions and functionalities have found wide applications from the fundamental studies to practical uses. In this research patchy micelles with thiol groups in the patches were prepared based on coassembly of free block copolymer chains and block copolymer brushes on silica particles. Thiol-terminated and cyanoisopropyl-capped polystyrene-block-poly(N-isopropylacrylamide) block copolymers (PS-b-PNIPAM-SH and PS-b-PNIPAM-CIP) were synthesized by reversible addition-fragmentation chain transfer polymerization and chemical modifications. Pyridyl disulfide-functionalized silica particles (SiO2-SS-Py) were prepared by four-step surface chemical reactions. PS-b-PNIPAM brushes on silica particles were prepared by thiol-disulfide exchange reaction between PS-b-PNIPAM-SH and SiO2-SS-Py. Surface micelles on silica particles were prepared by coassembly of PS-b-PNIPAM-CIP and block copolymer brushes. Upon cleavage of the surface micelles from silica particles, patchy micelles with thiol groups in the patches were obtained. Dynamic light scattering, transmission electron microscopy, and zeta-potential measurements demonstrate the preparation of patchy micelles. Gold nanoparticles can be anchored onto the patchy micelles through S-Au bonds, and asymmetric hybrid structures are formed. The thiol groups can be oxidized to disulfides, which results in directional assembly of the patchy micelles. The self-assembly behavior of the patchy micelles was studied experimentally and by computer simulation.

  5. Strategies for Controlled Placement of Nanoscale Building Blocks

    PubMed Central

    2007-01-01

    The capability of placing individual nanoscale building blocks on exact substrate locations in a controlled manner is one of the key requirements to realize future electronic, optical, and magnetic devices and sensors that are composed of such blocks. This article reviews some important advances in the strategies for controlled placement of nanoscale building blocks. In particular, we will overview template assisted placement that utilizes physical, molecular, or electrostatic templates, DNA-programmed assembly, placement using dielectrophoresis, approaches for non-close-packed assembly of spherical particles, and recent development of focused placement schemes including electrostatic funneling, focused placement via molecular gradient patterns, electrodynamic focusing of charged aerosols, and others. PMID:21794185

  6. 31 CFR 593.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Blocked account; blocked property. 593.301 Section 593.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR...

  7. 31 CFR 593.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Blocked account; blocked property. 593.301 Section 593.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR...

  8. 31 CFR 593.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Blocked account; blocked property. 593.301 Section 593.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR...

  9. 31 CFR 593.301 - Blocked account; blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Blocked account; blocked property. 593.301 Section 593.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR...

  10. 31 CFR 547.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Blocked account; blocked property. 547.302 Section 547.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS...

  11. 31 CFR 547.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Blocked account; blocked property. 547.302 Section 547.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS...

  12. 31 CFR 547.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Blocked account; blocked property. 547.302 Section 547.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS...

  13. 31 CFR 547.302 - Blocked account; blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Blocked account; blocked property. 547.302 Section 547.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS...

  14. Aggravation of pre-existing atrioventricular block, Wenckebach type, provoked by application of X-ray contrast medium.

    PubMed

    Brodmann, Marianne; Seinost, Gerald; Stark, Gerhard; Pilger, Ernst

    2006-01-01

    Significant bradycardia followed by cardiac arrest related to single bolus administration of X-ray contrast medium into a peripheral artery has not, to our knowledge, been described in the literature. While performing a percutaneous transluminal angioplasty of the left superficial femoral artery in a 68-year old patient with a pre-existing atrioventricular (AV) block, Wenckebach type, he developed an AV block III after a single bolus injection of intra-arterial X-ray contrast medium. We believe that application of contrast medium causes a transitory ischemia in the obstructed vessel and therefore elevation of endogenous adenosine. In the case of a previously damaged AV node this elevation of endogenous adenosine may be responsible for the development of a short period of third-degree AV block.

  15. Liposomal bupivacaine as a single-injection peripheral nerve block: a dose-response study.

    PubMed

    Ilfeld, Brian M; Malhotra, Nisha; Furnish, Timothy J; Donohue, Michael C; Madison, Sarah J

    2013-11-01

    .14, 95% CI, -0.27 to 0.39, P = 0.707). The results of this investigation suggest that deposition of a liposomal bupivacaine formulation adjacent to the femoral nerve results in a partial sensory and motor block of >24 hours for the highest doses examined. However, the high variability of block magnitude among subjects and inverse relationship of dose and response magnitude attests to the need for a phase 3 study with a far larger sample size, and that these results should be viewed as suggestive, requiring confirmation in a future trial.

  16. Activation gating kinetics of GIRK channels are mediated by cytoplasmic residues adjacent to transmembrane domains.

    PubMed

    Sadja, Rona; Reuveny, Eitan

    2009-01-01

    G-protein-coupled inwardly rectifying potassium channels (GIRK/Kir3.x) are involved in neurotransmission-mediated reduction of excitability. The gating mechanism following G protein activation of these channels likely proceeds from movement of inner transmembrane helices to allow K(+) ions movement through the pore of the channel. There is limited understanding of how the binding of G-protein betagamma subunits to cytoplasmic regions of the channel transduces the signal to the transmembrane regions. In this study, we examined the molecular basis that governs the activation kinetics of these channels, using a chimeric approach. We identified two regions as being important in determining the kinetics of activation. One region is the bottom of the outer transmembrane helix (TM1) and the cytoplasmic domain immediately adjacent (the slide helix); and the second region is the bottom of the inner transmembrane helix (TM2) and the cytoplasmic domain immediately adjacent. Interestingly, both of these regions are sufficient in mediating the kinetics of fast activation gating. This result suggests that there is a cooperative movement of either one of these domains to allow fast and efficient activation gating of GIRK channels.

  17. Toxicity and bioavailability of metals in the Missouri River adjacent to a lead refinery

    USGS Publications Warehouse

    Chapman, Duane C.; Allert, Ann L.; Fairchild, James F.; May, Thomas W.; Schmitt, Christopher J.; Callahan, Edward V.

    2001-01-01

    This study is an evaluation of the potential environmental impacts of contaminated groundwater from the ASARCO metals refining facility adjacent to the Missouri River in Omaha, Nebraska. Surface waters, sediments, and sediment pore waters were collected from the Burt-Izard drain, which transects the facility, and from the Missouri River adjacent to the facility. Groundwater was also collected from the facility. Waters and sediments were analyzed for inorganic contaminants, and the toxicity of the waters was evaluated with the Ceriodaphnia dubia 7-day test. Concentrations of several elemental contaminants were highly elevated in the groundwater, but not in river sediment pore waters. Lead concentrations were moderately elevated in whole sediment at one site, but lead concentrations in pore waters were low due to apparent sequestration by acid-volatile sulfides. The groundwater sample was highly toxic to C. dubia, causing 100% mortality. Even at the lowest groundwater concentration tested (6.25%) C. dubia survival was reduced; however, at that concentration, reproduction was not significantly different from upstream porewater reference samples. Sediment pore waters were not toxic, except reproduction in pore water collected from one downstream site was somewhat reduced. The decrease in reproduction could not be attributed to measured elemental contaminants.

  18. Comparison of saddle, lumbar epidural and caudal blocks on anal sphincter tone: A prospective, randomized study.

    PubMed

    Shon, Yoon-Jung; Huh, Jin; Kang, Sung-Sik; Bae, Seung-Kil; Kang, Ryeong-Ah; Kim, Duk-Kyung

    2016-10-01

    Objective To compare the effects of saddle, lumbar epidural and caudal blocks on anal sphincter tone using anorectal manometry. Methods Patients undergoing elective anorectal surgery with regional anaesthesia were divided randomly into three groups and received a saddle (SD), lumbar epidural (LE), or caudal (CD) block. Anorectal manometry was performed before and 30 min after each regional block. The degree of motor blockade of the anal sphincter was compared using the maximal resting pressure (MRP) and the maximal squeezing pressure (MSP). Results The study analysis population consisted of 49 patients (SD group, n = 18; LE group, n = 16; CD group, n = 15). No significant differences were observed in the percentage inhibition of the MRP among the three regional anaesthetic groups. However, percentage inhibition of the MSP was significantly greater in the SD group (83.6 ± 13.7%) compared with the LE group (58.4 ± 19.8%) and the CD group (47.8 ± 16.9%). In all groups, MSP was reduced significantly more than MRP after each regional block. Conclusions Saddle block was more effective than lumbar epidural or caudal block for depressing anal sphincter tone. No differences were detected between lumbar epidural and caudal blocks.

  19. Sacroiliac Joint Fusion Minimally Affects Adjacent Lumbar Segment Motion: A Finite Element Study

    PubMed Central

    Kiapour, Ali; Yerby, Scott A.; Goel, Vijay K.

    2015-01-01

    Background Adjacent segment disease is a recognized consequence of fusion in the spinal column. Fusion of the sacroiliac joint is an effective method of pain reduction. Although effective, the consequences of sacroiliac joint fusion and the potential for adjacent segment disease for the adjacent lumbar spinal levels is unknown. The objective of this study was to quantify the change in range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments due to sacroiliac joint fusion and compare these changes to previous literature to assess the potential for adjacent segment disease in the lumbar spine. Methods An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the sacroiliac joint using three laterally placed triangular implants (iFuse Implant System, SI-BONE, Inc., San Jose, CA). The range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments were calculated using a hybrid loading protocol and compared with the intact range of motion in flexion, extension, lateral bending, and axial rotation. Results The range of motions of the treated sacroiliac joints were reduced in flexion, extension, lateral bending, and axial rotation, by 56.6%, 59.5%, 27.8%, and 53.3%, respectively when compared with the intact condition. The stiffening of the sacroiliac joint resulted in increases at the adjacent lumbar motion segment (L5-S1) for flexion, extension, lateral bending, and axial rotation, of 3.0%, 3.7%, 1.1%, and 4.6%, respectively. Conclusions Fusion of the sacroiliac joint resulted in substantial (> 50%) reductions in flexion, extension, and axial rotation of the sacroiliac joint with minimal (< 5%) increases in range of motion in the lumbar spine. Although the predicted increases in lumbar range of motion are minimal after sacroiliac joint fusion, the long-term clinical results remain to be investigated. PMID:26767156

  20. Sacroiliac Joint Fusion Minimally Affects Adjacent Lumbar Segment Motion: A Finite Element Study.

    PubMed

    Lindsey, Derek P; Kiapour, Ali; Yerby, Scott A; Goel, Vijay K

    2015-01-01

    Adjacent segment disease is a recognized consequence of fusion in the spinal column. Fusion of the sacroiliac joint is an effective method of pain reduction. Although effective, the consequences of sacroiliac joint fusion and the potential for adjacent segment disease for the adjacent lumbar spinal levels is unknown. The objective of this study was to quantify the change in range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments due to sacroiliac joint fusion and compare these changes to previous literature to assess the potential for adjacent segment disease in the lumbar spine. An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the sacroiliac joint using three laterally placed triangular implants (iFuse Implant System, SI-BONE, Inc., San Jose, CA). The range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments were calculated using a hybrid loading protocol and compared with the intact range of motion in flexion, extension, lateral bending, and axial rotation. The range of motions of the treated sacroiliac joints were reduced in flexion, extension, lateral bending, and axial rotation, by 56.6%, 59.5%, 27.8%, and 53.3%, respectively when compared with the intact condition. The stiffening of the sacroiliac joint resulted in increases at the adjacent lumbar motion segment (L5-S1) for flexion, extension, lateral bending, and axial rotation, of 3.0%, 3.7%, 1.1%, and 4.6%, respectively. Fusion of the sacroiliac joint resulted in substantial (> 50%) reductions in flexion, extension, and axial rotation of the sacroiliac joint with minimal (< 5%) increases in range of motion in the lumbar spine. Although the predicted increases in lumbar range of motion are minimal after sacroiliac joint fusion, the long-term clinical results remain to be investigated.