Science.gov

Sample records for administration bpa service

  1. BPA Facts

    SciTech Connect

    2014-03-01

    The Bonneville Power Administration is a federal nonprofit power marketing administration based in the Pacific Northwest . Although BPA is part of the U .S . Department of Energy, it is self-funding and covers its costs by selling its products and services . BPA markets wholesale electrical power from 31 federal hydro projects in the Columbia River Basin, one nonfederal nuclear plant and several small nonfederal power plants . The dams are operated by the U .S . Army Corps of Engineers and the Bureau of Reclamation . About 30 percent of the electric power used in the Northwest comes from BPA . BPA’s resources — primarily hydroelectric — make its power nearly carbon free . BPA also operates and maintains about three- fourths of the high-voltage transmission in its service territory . BPA’s service territory includes Idaho, Oregon, Washington, western Montana and small parts of eastern Montana, California, Nevada, Utah and Wyoming . BPA promotes energy efficiency, renewable resources and new technologies that improve its ability to deliver on its mission . BPA also funds regional efforts to protect and enhance fish and wildlife populations affected by hydropower development in the Columbia River Basin . BPA is committed to public service and seeks to make its decisions in a manner that provides opportunities for input from stakeholders . In its vision statement, BPA dedicates itself to providing high system reliability, low rates consistent with sound business principles, environmental stewardship and accountability

  2. Extensive metabolism and route-dependent pharmacokinetics of bisphenol A (BPA) in neonatal mice following oral or subcutaneous administration.

    PubMed

    Draganov, Dragomir I; Markham, Dan A; Beyer, Dieter; Waechter, John M; Dimond, Stephen S; Budinsky, Robert A; Shiotsuka, Ronald N; Snyder, Stephanie A; Ehman, Kimberly D; Hentges, Steven G

    2015-07-01

    Orally administered bisphenol A (BPA) undergoes efficient first-pass metabolism to produce the inactive conjugates BPA-glucuronide (BPA-G) and BPA-sulfate (BPA-S). This study was conducted to evaluate the pharmacokinetics of BPA, BPA-G and BPA-S in neonatal mice following the administration of a single oral or subcutaneous (SC) dose. This study consisted of 3 phases: (1) mass-balance phase in which effective dose delivery procedures for oral or SC administration of (3)H-BPA to postnatal day three (PND3) mice were developed; (2) pharmacokinetic phase during which systemic exposure to total (3)H-BPA-derived radioactivity in female PND3 mice was established; and (3) metabolite profiling phase in which 50 female PND3 pups received either a single oral or SC dose of (3)H-BPA. Blood was collected from 5 pups/route/time-point at various times post-dosing, the blood plasma samples were pooled by group, and time-point and samples were profiled by HPLC with fraction collection. Fractions were analyzed for total radioactivity and data used to reconstruct radiochromatograms and to integrate individual peaks. The identity of the BPA, BPA-G, and BPA-S peaks was confirmed using authentic standards and LC-MS/MS analysis. The result of this study revealed that female PND3 mice have the capacity to metabolize BPA to BPA-G, BPA-S and other metabolites after both routes of administration. Systemic exposure to free BPA is route-dependent as the plasma concentrations were lower following oral administration compared to SC injection.

  3. BPA Statutes.

    SciTech Connect

    United States. Bonneville Power Administration.

    1999-08-01

    This report contains the Bonneville Power Administration's (BPA's) authorizing statutes--the Bonneville Project Act, the Federal Columbia River Transmission System Act, the Pacific Northwest Electric Power Planning and Conservation Act and other laws that contain provisions that define BPA's mission and affect the way it is carried out.

  4. What is BPA?

    SciTech Connect

    United States. Bonneville Power Administration.

    1996-09-01

    This PR pamphlet explains what BPA (Bonneville Power Administration) is (a Federal agency with a Northwest focus). It plays a role in balancing river uses; power revenues pay BPA costs; renewable resource aspects are discussed; fish and wildlife protection are discussed; the BPA power grid is disucssed; and how BPA disposes of its power is discussed.

  5. The administration of human services.

    PubMed

    Hasenfeld, Y

    1985-05-01

    Human service programs have gone from a period of rapid growth in the 1960s and early 1970s to a period of retrenchment in the 1980s. The changing political and economic context has forced these programs to undergo major organizational transformations and to adopt different administrative strategies. These include degovernmentalization of social services, reliance on cutback management, and deprofessionalization of human-service workers. The article explores the implications of these developments on the delivery of services to the public.

  6. BPA Statutes.

    SciTech Connect

    United States. Bonneville Power Administration.

    1995-01-01

    This publication includes the Bonneville Power Administration`s (BPA) authorities. It combines the two previous booklets of BPA authorities` and adds: sections of certain Appropriation Acts affecting BPA; a list of all other Appropriation Acts affecting BPA; a list of the acts authorizing Federal hydroelectric dams in the Columbia River Basin; portions of the Energy Policy Act of 1992 that specifically apply to BPA; portions of the Federal Power Act to provide context for the Energy Policy Act. The laws are in their United States Code format, rather than in the Public Law format as passed. Thus, the citation for Bonneville Project Act section 2(f) is shown as 16 USC {section}832a(f). Most people are familiar with the Public Law citations, so they have been retained and appear in italics at the end of each paragraph. In addition, later amendments to earlier laws are reflected in the United States Code language. For example, the Preference Act`s definition of ``Pacific Northwest`` (16 USC {section}837(b)) reflects the Northwest Power Act`s amendment of that term. The laws are presented in the numerical order they appear in the United States Code, rather than in the order in which they became law. Therefore, the Energy Policy Act of 1992 is presented first. This booklet is not, nor is it intended to be, an official reporter. All citations should be made to the United States Code or some other officially recognized reporter.

  7. Multifunctional data acquisition and analysis and optical sensors: a Bonneville Power Administration (BPA) update

    NASA Astrophysics Data System (ADS)

    Erickson, Dennis C.; Donnelly, Matt K.

    1995-04-01

    The authors present a design concept describing a multifunctional data acquisition and analysis architecture for advanced power system monitoring. The system is tailored to take advantage of the salient features of low energy sensors, particularly optical types. The discussion of the system concept and optical sensors is based on research at BPA and PNL and on progress made at existing BPA installations and other sites in the western power system.

  8. Public Administration of Recreational Services. Second Edition.

    ERIC Educational Resources Information Center

    Hjelte, George; Shivers, Jay S.

    Oriented toward a consideration of administration from the standpoint of departmental problems, this textbook deals with administrative techniques and practices pertaining to public administration of recreational services. It covers organization, operation, planning, development, and managerial procedures, and also describes the basic elements of…

  9. Department of Defense / General Services Administration / National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... (DoD), General Services Administration (GSA), and National Aeronautics and Space Administration (NASA...., Washington, DC 20405, (202) 501-4755. SUPPLEMENTARY INFORMATION: DoD, GSA, and NASA, under their several... Acquisition Policy. DOD/GSA/NASA (FAR)--Final Rule Stage Regulation Sequence Title Identifier Number...

  10. Boron biodistribution for BNCT in the hamster cheek pouch oral cancer model: Combined administration of BSH and BPA

    SciTech Connect

    D.W. Nigg; William Bauer; Various Others

    2014-06-01

    Sodium mercaptoundecahydro-closo-dodecaborate (BSH) is being investigated clinically for BNCT. We examined the biodistribution of BSH and BPA administered jointly in different proportions in the hamster cheek pouch oral cancer model. The 3 assayed protocols were non-toxic, and showed preferential tumor boron uptake versus precancerous and normal tissue and therapeutic tumor boron concentration values (70–85 ppm). All 3 protocols warrant assessment in BNCT studies to contribute to the knowledge of (BSH+BPA)-BNCT radiobiology for head and neck cancer and optimize therapeutic efficacy.

  11. 77 FR 62243 - Health Resources and Services Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-12

    ... HUMAN SERVICES Health Resources and Services Administration National Advisory Council on the National...., November 2, 2012--8:00 a.m.-12:00 p.m. Place: Health Resources and Services Administration (HRSA), Parklawn..., Bureau of Clinician Recruitment and Service, Health Resources and Services Administration,...

  12. 78 FR 29245 - U.S. General Services Administration Federal Property Management Regulations; Administrative Wage...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... Administration Federal Property Management Regulations; Administrative Wage Garnishment AGENCY: Office of the... amending the U.S. General Services Administration Property Management Regulation (GSPMR) to remove... telephone number. The Administrative Wage Garnishment Code of Federal Regulations (CFR) Parts affected...

  13. 78 FR 63177 - Order on Voluntary Remand and Clarifying Policy on Filing of Reactive Power Service Rate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... Generation Sources Service (reactive power) to the Bonneville Power Administration (Bonneville or BPA) is a....'' \\5\\ The Commission stated that ``Chehalis has been providing reactive power to BPA pursuant to an... interconnection agreement between Chehalis and BPA was required to be filed prior to May 2005, even though it...

  14. 7 CFR 2.57 - Administrator, Food and Nutrition Service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Administrator, Food and Nutrition Service. 2.57... for Food, Nutrition, and Consumer Services § 2.57 Administrator, Food and Nutrition Service. (a... delegations of authority are made by the Under Secretary for Food, Nutrition, and Consumer Services to...

  15. 7 CFR 2.57 - Administrator, Food and Nutrition Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Administrator, Food and Nutrition Service. 2.57... for Food, Nutrition, and Consumer Services § 2.57 Administrator, Food and Nutrition Service. (a... delegations of authority are made by the Under Secretary for Food, Nutrition, and Consumer Services to...

  16. 7 CFR 2.57 - Administrator, Food and Nutrition Service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Administrator, Food and Nutrition Service. 2.57... for Food, Nutrition, and Consumer Services § 2.57 Administrator, Food and Nutrition Service. (a... delegations of authority are made by the Under Secretary for Food, Nutrition, and Consumer Services to...

  17. 7 CFR 2.57 - Administrator, Food and Nutrition Service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administrator, Food and Nutrition Service. 2.57... for Food, Nutrition, and Consumer Services § 2.57 Administrator, Food and Nutrition Service. (a... delegations of authority are made by the Under Secretary for Food, Nutrition, and Consumer Services to...

  18. Administration of Educational Services: A Glossary of Basic Administration Terminology.

    ERIC Educational Resources Information Center

    Wheelbarger, J. J.

    From "achievement motivation" and "administration" to "Theory Z" and "viscidity and hedonic tone," this glossary defines 87 terms as they are used in educational administration. The terms include philosophical, psychological, organizational, and social concepts, but they all are employed in the theory and practice of administration. A short…

  19. BPA's Eighth Annual Energy Conservation Management Conference : Proceedings.

    SciTech Connect

    Energy Conservation Management Conference; United States. Bonneville Power Administration.

    1981-01-01

    The five-year energy conservation program at Bonneville Power Administration (BPA) is described at the conference. An overview of the program is presented. Topics covered in panel discussions include: how utilities can work effectively with weatherization contractors, homebuilders, energy auditors, and weatherization material suppliers; mechanisms for implementing conservation programs in the commercial sector; experiences gained in existing residential weatherization programs; and streamlining relationships between consumers, utilities, and BPA in providing services and getting feedback. The planning, programming, technical assistance, and engineering thrusts of BPA's conservation programs are discussed. Indoor air quality, renewable energy, and the regulator's role in relationships to energy conservation are discussed. Passive solar programs, DOE initiatives in solar and conservation for buildings, conservation potential in the commercial and industrial sectors, and current conservation research and development are also discussed. (MCW)

  20. 76 FR 5375 - Public Availability of General Services Administration FY 2010 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... ADMINISTRATION Public Availability of General Services Administration FY 2010 Service Contract Inventory AGENCY: Office of Acquisition Policy; General Services Administration (GSA). ACTION: Notice. SUMMARY: This notice... Consolidated Appropriations Act of 2010 (Pub. L. 111-117), GSA is publishing this notice to advise the...

  1. 41 CFR 101-29.301 - General Services Administration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true General Services Administration. 101-29.301 Section 101-29.301 Public Contracts and Property Management Federal Property... PRODUCT DESCRIPTIONS 29.3-Responsibilities § 101-29.301 General Services Administration....

  2. 41 CFR 101-29.301 - General Services Administration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true General Services Administration. 101-29.301 Section 101-29.301 Public Contracts and Property Management Federal Property... PRODUCT DESCRIPTIONS 29.3-Responsibilities § 101-29.301 General Services Administration....

  3. General Services Administration Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... fall 2007 edition, the Internet has been the basic means for disseminating the Unified Agenda. The... purchase of products and services to be used to facilitate recovery from a major disaster declared by the President or to facilitate recovery from terrorism, or nuclear, biological, chemical, or radiological...

  4. School-Based Health Services: Administrative Rules.

    ERIC Educational Resources Information Center

    Oregon State Dept. of Human Resources, Salem.

    This manual outlines the State of Oregon's program to reimburse medical providers furnishing health services to students with medical disabilities in special education settings. The program was established to comply with federal provisions of the Individuals with Disabilities Education Act of 1990. The guide will assist school personnel in…

  5. 51. Roof plans, General Services Administration, Construction Management Division, Region ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Roof plans, General Services Administration, Construction Management Division, Region 2, New York, October 29, 1976. Scale 1/31=1. - U.S. Navy Fleet Supply Base, Storehouse No. 1, 830 Third Avenue, Brooklyn, Kings County, NY

  6. 7 CFR 2.57 - Administrator, Food and Nutrition Service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Administrator, Food and Nutrition Service. 2.57 Section 2.57 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY THE SECRETARY OF AGRICULTURE AND GENERAL OFFICERS OF THE DEPARTMENT Delegations of Authority by the Under Secretary for Food, Nutrition, and Consumer Services...

  7. 77 FR 76052 - Health Resources and Services Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Agency Information Collection Activities... States Code, as amended by the Paperwork Reduction Act of 1995, Public Law 104-13), the Health...

  8. 48 CFR 42.203 - Contract administration services directory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contract administration services directory. 42.203 Section 42.203 Federal Acquisition Regulations System FEDERAL ACQUISITION... services within designated geographic areas and at specified contractor plants. Federal agencies may...

  9. 48 CFR 42.203 - Contract administration services directory.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contract administration services directory. 42.203 Section 42.203 Federal Acquisition Regulations System FEDERAL ACQUISITION... services within designated geographic areas and at specified contractor plants. Federal agencies may...

  10. 9 CFR 351.7 - Administration of certification service program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Administration of certification service program. 351.7 Section 351.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS...

  11. 9 CFR 351.7 - Administration of certification service program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Administration of certification service program. 351.7 Section 351.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS...

  12. 9 CFR 351.7 - Administration of certification service program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Administration of certification service program. 351.7 Section 351.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS...

  13. 9 CFR 351.7 - Administration of certification service program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Administration of certification service program. 351.7 Section 351.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS...

  14. 9 CFR 351.7 - Administration of certification service program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Administration of certification service program. 351.7 Section 351.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT...

  15. Developing a Performance Measurement System for University Central Administrative Services

    ERIC Educational Resources Information Center

    Arena, Marika; Arnaboldi, Michela; Azzone, Giovanni; Carlucci, Paola

    2009-01-01

    Central administrative services have recently received increasing attention from practitioners and academics due to the challenging need to both manage scarce resources and provide high-quality services. In this context, performance measurement systems (PMSs) may assume a central role, although an unresolved debate remains on the claimed benefits…

  16. 77 FR 66466 - General Services Administration Regulation; Information Collection; Packing List Clause

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-05

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES ADMINISTRATION General Services Administration Regulation; Information Collection; Packing List Clause AGENCY... information collection documents from the General Services Administration, Regulatory Secretariat (MVCB),...

  17. 77 FR 5020 - General Services Administration Acquisition Regulation; Information Collection; GSA Form 527...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... ADMINISTRATION General Services Administration Acquisition Regulation; Information Collection; GSA Form 527... and Financial Information'' on your attached document. Fax: (202) 501-4067. Mail: General Services... provided. SUPPLEMENTARY INFORMATION: A. Purpose The General Services Administration will be requesting...

  18. 78 FR 59161 - Designation of Officers of the General Services Administration to Act as Administrator of General...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    .... (Presidential Sig.) THE WHITE HOUSE, Washington, September 20, 2013. [FR Doc. 2013-23601 Filed 9-25-13; 8:45 am... of the General Services Administration to Act as Administrator of General Services Memorandum for the Administrator of General Services By the authority vested in me as President by the Constitution and the laws...

  19. Public health service administration and academia. A joint venture.

    PubMed

    Campbell, B F; King, J B

    1992-12-01

    Joint ventures between service and academia are designed to enhance the quality of client services, enrich faculty teaching experiences and skills, and strengthen communication channels. The joint venture described in this article is an example of how public health nursing services and academia can be united through faculty participation in administration. Included in the discussion are the impetus for the project, the contract negotiations, the positive outcomes and disadvantages of the venture, and questions that should be raised when a similar venture is considered.

  20. 41 CFR 101-30.704-1 - General Services Administration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATALOG SYSTEM 30.7-Item Reduction Program § 101-30.704-1 General Services Administration. (a) The General... nonconcurrences from all civil agencies are accurately reflected. (7) Register into the Federal catalog system... agencies (except direct submitters of catalog data to DLSC) will also be forwarded covering letters...

  1. 41 CFR 101-30.704-1 - General Services Administration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATALOG SYSTEM 30.7-Item Reduction Program § 101-30.704-1 General Services Administration. (a) The General... nonconcurrences from all civil agencies are accurately reflected. (7) Register into the Federal catalog system... agencies (except direct submitters of catalog data to DLSC) will also be forwarded covering letters...

  2. 41 CFR 101-30.704-1 - General Services Administration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATALOG SYSTEM 30.7-Item Reduction Program § 101-30.704-1 General Services Administration. (a) The General... nonconcurrences from all civil agencies are accurately reflected. (7) Register into the Federal catalog system... agencies (except direct submitters of catalog data to DLSC) will also be forwarded covering letters...

  3. 7 CFR 2.79 - Administrator, Agricultural Marketing Service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... delegated to the Secretary by Executive Order 12580, 3 CFR, 1987 Comp., p. 193, under the following... pollution control standards and section 1-601 of Executive Order 12088, 3 CFR, 1978 Comp., p. 243, to enter... 7 Agriculture 1 2010-01-01 2010-01-01 false Administrator, Agricultural Marketing Service....

  4. 7 CFR 2.79 - Administrator, Agricultural Marketing Service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... delegated to the Secretary by Executive Order 12580, 3 CFR, 1987 Comp., p. 193, under the following... pollution control standards and section 1-601 of Executive Order 12088, 3 CFR, 1978 Comp., p. 243, to enter... 7 Agriculture 1 2011-01-01 2011-01-01 false Administrator, Agricultural Marketing Service....

  5. 3. Photocopy of a photograph (from the General Services Administration, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of a photograph (from the General Services Administration, Auburn, Washington) Photographer unknown, November 1962 IMMIGRATION RESIDENCE PRIOR TO ALTERATION OF THE PORCH STAIRS AND INSTALLATION OF SCREENS ON THE FRONT PORCH, VIEW TO THE SOUTHWEST - U.S. Border Inspection Station, Immigation Officers Residence, West side of State Route 95, Eastport, Boundary County, ID

  6. 7 CFR 2.68 - Administrator, National Agricultural Statistics Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... committees concerned with agricultural science, education, and development activities, including library and... Service. 2.68 Section 2.68 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.68 Administrator, National...

  7. 7 CFR 2.67 - Administrator, Economic Research Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... with agricultural science, education, and development activities, including library and information... 2.67 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY THE SECRETARY OF... Research, Education, and Economics § 2.67 Administrator, Economic Research Service. (a)...

  8. 7 CFR 2.47 - Administrator, Rural Utilities Service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administrator, Rural Utilities Service. 2.47 Section 2.47 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY THE SECRETARY OF AGRICULTURE AND GENERAL OFFICERS OF THE DEPARTMENT Delegations of Authority by the Under Secretary for...

  9. Mary Wakefield: Health Resources and Services Administrator. Interview.

    PubMed

    Wakefield, Mary

    2014-06-01

    Dr. Mary Wakefield is the administrator of the Health Resources and Services Administration. She came from the University of North Dakota, where she directed the Center for Rural Health. She has served as director of the Center for Health Policy, Research and Ethics at George Mason University and has worked with the World Health Organization's Global Programme on AIDS in Geneva, Switzerland. She is a fellow in the American Academy of Nursing and was elected to the Institute of Medicine of the National Academies. A native of North Dakota, Wakefield holds a doctoral degree in nursing from the University of Texas.

  10. 76 FR 81941 - General Services Administration Acquisition Regulation; Information Collection; Price Reductions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES ADMINISTRATION General Services Administration Acquisition Regulation; Information Collection; Price Reductions.... FOR FURTHER INFORMATION CONTACT: Ms. Dana Munson, General Services Acquisition Policy Division,...

  11. Economic Outcome of Employment for Older Participants in Rehabilitation Services Funded by the Rehabilitation Services Administration

    ERIC Educational Resources Information Center

    Wadsworth, John S.; Estrada-Hernandez, Noel; Kampfe, Charlene M.; Smith, S. Mae

    2008-01-01

    The purpose of this study was to determine if persons who were age 65 or older and who participated in vocational rehabilitation programs funded by the Rehabilitation Services Administration (RSA) experienced an increase in earnings from paid employment at the conclusion of services. Preservice and postservice earnings for 9,787 consumers of RSA…

  12. Developing leaders vs training administrators in the health services.

    PubMed Central

    Legnini, M W

    1994-01-01

    In these difficult times, health care institutions need leaders, not simply managers. Leaders' breadth of skills and perspective come from understanding the values involved in health care delivery; managers know the right way to do things, but leaders know which are the right things to do. Schools of public health are moving away from their potential contribution to leadership development in health services administration. The result is a lack of accountability to the community. Leadership skills and an examination of values should be part of health services administration programs in schools of public health, which should see their mission as helping to identify and train leaders, not simply technical specialists in management. PMID:7943472

  13. 47 CFR 54.701 - Administrator of universal service support mechanisms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Administrator of universal service support mechanisms. 54.701 Section 54.701 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.701 Administrator of universal service support mechanisms. (a) The...

  14. Creating a resource database for nursing service administration.

    PubMed

    Clougherty, J; McCloskey, J C; Johnson, M; Casula, M; Gardner, D; Kelly, K; Maas, M; Delaney, C; Blegen, M

    1991-01-01

    In response to the current information explosion in nursing service administration (NSA), the authors felt a need to collect and organize available resources for use by their faculty and graduate students. An electronic database was developed to facilitate the use of the collected print and software resources. This article describes the creation of the NSA Resource Database from the time the need for it was realized to its completion. There is discussion regarding the criteria used for writing the database, what the database screens look like and why and what the database contains. The article also discusses the use and users of the NSA Resource Database to date. PMID:2036589

  15. The Health Resources and Services Administration diversity data collection.

    PubMed

    White, Kathleen M; Zangaro, George; Kepley, Hayden O; Camacho, Alex

    2014-01-01

    The Health Resources and Services Administration maintains a strong emphasis on increasing the diversity of the health-care workforce through its grant programs. Increasing the diversity of the workforce is important for reducing health disparities in the population caused by socioeconomic, geographic, and race/ethnicity factors because evidence suggests that minority health professionals are more likely to serve in areas with a high proportion of underrepresented racial and ethnic minority groups. The data show success in increasing the diversity of enrollees in five nursing programs.

  16. [The approach of sciences of complexity in health services administration].

    PubMed

    Fajardo-Ortiz, Guillermo; Ortiz-Montalvo, Armando

    2013-01-01

    Historically, health services administration has been managed under a Taylorist, Fayolist, humanist and bureaucratic focus approach. However, today dynamic and competitive behaviors that require others approaches in management are developing. Because of the social, scientific and technological changes that are occurring, it is necessary to abandon hierarchical and authoritarian schemes, "up and down" lines, prescriptive rules and order line up must be left behind. Health services administration is an adapted complex system that is not proportional, neither predictable in direction or magnitude. A new proposal is to focus on the sciences of complexity, where the social factors, materials, economics, human and ethics coincide with order and disorder, reason and unreason, and in which we must accept that the phenomenon that emerges creates different organizing different structures from the addition or subtraction of components. There is distance in the process of cause and direct effect. The mirage from the sciences of complexity are trans-disciplinary and we have accepted this in others branches of knowledge, such as quantum physics, non-linear mathematics and cybernetics, so we have to accept the influence of entropy, non-entropy, attractors, the theory of chaos and fractals. PMID:23693104

  17. [The approach of sciences of complexity in health services administration].

    PubMed

    Fajardo-Ortiz, Guillermo; Ortiz-Montalvo, Armando

    2013-01-01

    Historically, health services administration has been managed under a Taylorist, Fayolist, humanist and bureaucratic focus approach. However, today dynamic and competitive behaviors that require others approaches in management are developing. Because of the social, scientific and technological changes that are occurring, it is necessary to abandon hierarchical and authoritarian schemes, "up and down" lines, prescriptive rules and order line up must be left behind. Health services administration is an adapted complex system that is not proportional, neither predictable in direction or magnitude. A new proposal is to focus on the sciences of complexity, where the social factors, materials, economics, human and ethics coincide with order and disorder, reason and unreason, and in which we must accept that the phenomenon that emerges creates different organizing different structures from the addition or subtraction of components. There is distance in the process of cause and direct effect. The mirage from the sciences of complexity are trans-disciplinary and we have accepted this in others branches of knowledge, such as quantum physics, non-linear mathematics and cybernetics, so we have to accept the influence of entropy, non-entropy, attractors, the theory of chaos and fractals.

  18. State administration and financing of family planning services.

    PubMed

    Weinberg, D

    1972-04-01

    A 1971 survey by the Center for Family Planning Program Development consisted of a questionnaire mailed to health and welfare directors in 50 states and 5 federal jurisdictions concerning their family planning policies and administrative practices. 52 agencies responded; Guam, Mississippi, and Louisiana did not. The major funding for state health agencies was allocated by HEW and by maternal and child health (MCH) formula grants under Title 5 of the Social Security Act. 11 states made additional expenditures of $1.7 million for a variety of purposes. 21 states required local welfare departments to purchase services under the Medicaid program established by Title 19 of the Social Security Act. Administration was assigned to specific organizations within the state health agencies. 31 states reported a total of 128 full-time professional personnel, with 90 assigned at state headquarters level. In general, on a state-by-state basis, the full-time staff does not correspond to the size of the appropriations. Survey findings were useful measures of resource commitments to family planning services by state health and welfare agencies and provided data on future levels of resource requirements. PMID:5052570

  19. BPA Prepares for the 21st Century.

    SciTech Connect

    United States. Bonneville Power Administration.

    1998-04-01

    This is a brief review of the state of the Bonneville Power Administration. It reviews BPA`s competitive status, fish and wildlife funding, cost structure of the federal system, subscription sales of electricity, emergency cost recovery, cost reduction measures, transmission access and operation, and the 1998 power rate case decision making process.

  20. 77 FR 7183 - Public Availability of the National Aeronautics and Space Administration FY 2011 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... From the Federal Register Online via the Government Publishing Office NATIONAL AERONAUTICS AND SPACE ADMINISTRATION Public Availability of the National Aeronautics and Space Administration FY 2011 Service Contract Inventory AGENCY: National Aeronautics and Space Administration. ACTION: Notice of...

  1. 48 CFR 339.7001 - Request for approval to make an award to other than a GSA BPA holder.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... make an award to other than a GSA BPA holder. 339.7001 Section 339.7001 Federal Acquisition Regulations... Services 339.7001 Request for approval to make an award to other than a GSA BPA holder. The Contracting... micro-purchase threshold, that obtaining the required services from a source other than a GSA BPA...

  2. 48 CFR 339.7001 - Request for approval to make an award to other than a GSA BPA holder.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... make an award to other than a GSA BPA holder. 339.7001 Section 339.7001 Federal Acquisition Regulations... Services 339.7001 Request for approval to make an award to other than a GSA BPA holder. The Contracting... micro-purchase threshold, that obtaining the required services from a source other than a GSA BPA...

  3. 48 CFR 339.7001 - Request for approval to make an award to other than a GSA BPA holder.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... make an award to other than a GSA BPA holder. 339.7001 Section 339.7001 Federal Acquisition Regulations... Services 339.7001 Request for approval to make an award to other than a GSA BPA holder. The Contracting... micro-purchase threshold, that obtaining the required services from a source other than a GSA BPA...

  4. 48 CFR 339.7001 - Request for approval to make an award to other than a GSA BPA holder.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... make an award to other than a GSA BPA holder. 339.7001 Section 339.7001 Federal Acquisition Regulations... Services 339.7001 Request for approval to make an award to other than a GSA BPA holder. The Contracting... micro-purchase threshold, that obtaining the required services from a source other than a GSA BPA...

  5. 48 CFR 339.7001 - Request for approval to make an award to other than a GSA BPA holder.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... make an award to other than a GSA BPA holder. 339.7001 Section 339.7001 Federal Acquisition Regulations... Services 339.7001 Request for approval to make an award to other than a GSA BPA holder. The Contracting... micro-purchase threshold, that obtaining the required services from a source other than a GSA BPA...

  6. Principal Investigator and Department Administrator Perceptions of Services Provided by Offices of Research Administration at Research Universities

    ERIC Educational Resources Information Center

    Cole, Kimberley W.

    2010-01-01

    The purpose of this research study was to determine what service attributes were perceived as important factors for a successful Office of Research Administration (ORA) to provide to principal investigators and department administrators. Initially established more than 50 years ago, The Office of Research Administration (ORA) has evolved into an…

  7. 78 FR 27208 - Applications for New Awards; Rehabilitation Services Administration-Centers for Independent Living

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... of individual services designed to help consumers move out of institutions and into community-based... Applications for New Awards; Rehabilitation Services Administration--Centers for Independent Living AGENCY: Office of Special Education and Rehabilitative Services, Department of Education. ACTION:...

  8. NIEHS/FDA CLARITY-BPA research program update.

    PubMed

    Heindel, Jerrold J; Newbold, Retha R; Bucher, John R; Camacho, Luísa; Delclos, K Barry; Lewis, Sherry M; Vanlandingham, Michelle; Churchwell, Mona I; Twaddle, Nathan C; McLellen, Michelle; Chidambaram, Mani; Bryant, Matthew; Woodling, Kellie; Gamboa da Costa, Gonçalo; Ferguson, Sherry A; Flaws, Jodi; Howard, Paul C; Walker, Nigel J; Zoeller, R Thomas; Fostel, Jennifer; Favaro, Carolyn; Schug, Thaddeus T

    2015-12-01

    Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S. Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program.

  9. NIEHS/FDA CLARITY-BPA research program update.

    PubMed

    Heindel, Jerrold J; Newbold, Retha R; Bucher, John R; Camacho, Luísa; Delclos, K Barry; Lewis, Sherry M; Vanlandingham, Michelle; Churchwell, Mona I; Twaddle, Nathan C; McLellen, Michelle; Chidambaram, Mani; Bryant, Matthew; Woodling, Kellie; Gamboa da Costa, Gonçalo; Ferguson, Sherry A; Flaws, Jodi; Howard, Paul C; Walker, Nigel J; Zoeller, R Thomas; Fostel, Jennifer; Favaro, Carolyn; Schug, Thaddeus T

    2015-12-01

    Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S. Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program. PMID:26232693

  10. 20 CFR 601.6 - Grants for administration of unemployment compensation laws and employment service.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Grants for administration of unemployment... administration of unemployment compensation laws and employment service. Grants of funds for administration of State unemployment compensation laws and public employment service programs are made to States...

  11. 20 CFR 601.6 - Grants for administration of unemployment compensation laws and employment service.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false Grants for administration of unemployment... administration of unemployment compensation laws and employment service. Grants of funds for administration of State unemployment compensation laws and public employment service programs are made to States...

  12. 20 CFR 601.6 - Grants for administration of unemployment compensation laws and employment service.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Grants for administration of unemployment... administration of unemployment compensation laws and employment service. Grants of funds for administration of State unemployment compensation laws and public employment service programs are made to States...

  13. 20 CFR 601.6 - Grants for administration of unemployment compensation laws and employment service.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false Grants for administration of unemployment... administration of unemployment compensation laws and employment service. Grants of funds for administration of State unemployment compensation laws and public employment service programs are made to States...

  14. 20 CFR 601.6 - Grants for administration of unemployment compensation laws and employment service.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Grants for administration of unemployment... administration of unemployment compensation laws and employment service. Grants of funds for administration of State unemployment compensation laws and public employment service programs are made to States...

  15. 28 CFR 16.102 - Exemption of Drug Enforcement Administration and Immigration and Naturalization Service Joint...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration and Immigration and Naturalization Service Joint System of Records. 16.102 Section 16.102 Judicial... Systems Under the Privacy Act § 16.102 Exemption of Drug Enforcement Administration and Immigration and..., the Immigration and Naturalization Service or the Drug Enforcement Administration will...

  16. 28 CFR 16.102 - Exemption of Drug Enforcement Administration and Immigration and Naturalization Service Joint...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration and Immigration and Naturalization Service Joint System of Records. 16.102 Section 16.102 Judicial... Systems Under the Privacy Act § 16.102 Exemption of Drug Enforcement Administration and Immigration and..., the Immigration and Naturalization Service or the Drug Enforcement Administration will...

  17. 28 CFR 16.102 - Exemption of Drug Enforcement Administration and Immigration and Naturalization Service Joint...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration and Immigration and Naturalization Service Joint System of Records. 16.102 Section 16.102 Judicial... Systems Under the Privacy Act § 16.102 Exemption of Drug Enforcement Administration and Immigration and..., the Immigration and Naturalization Service or the Drug Enforcement Administration will...

  18. 28 CFR 16.102 - Exemption of Drug Enforcement Administration and Immigration and Naturalization Service Joint...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Administration and Immigration and Naturalization Service Joint System of Records. 16.102 Section 16.102 Judicial... Systems Under the Privacy Act § 16.102 Exemption of Drug Enforcement Administration and Immigration and..., the Immigration and Naturalization Service or the Drug Enforcement Administration will...

  19. 28 CFR 16.102 - Exemption of Drug Enforcement Administration and Immigration and Naturalization Service Joint...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration and Immigration and Naturalization Service Joint System of Records. 16.102 Section 16.102 Judicial... Systems Under the Privacy Act § 16.102 Exemption of Drug Enforcement Administration and Immigration and..., the Immigration and Naturalization Service or the Drug Enforcement Administration will...

  20. 78 FR 6168 - Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... ADMINISTRATION Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2012 Service... Appropriations Act of 2010 (Pub. L. 111-117), we are publishing this notice to advise the public of...

  1. 77 FR 3836 - Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... ADMINISTRATION Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2011 Service... Appropriations Act of 2010 (Pub. L. 111-117), we are publishing this notice to advise the public of...

  2. Bonneville Power Administration 1997 Annual Report.

    SciTech Connect

    United States. Bonneville Power Administration.

    1998-01-01

    The Bonneville Power Administration`s 60th anniversary year exceeded expectations. Net revenues were the best since 1991, which demonstrates that earlier decisions to transform BPA into a smaller, cost-conscious, customer-focused organization were the correct decisions. The region`s evaluation of the agency`s role in the Northwest was as gratifying as the positive financial position. Through the Comprehensive Review of the Northwest Energy System, the region concluded that BPA has been and must continue to be an important economic and environmental benefit to the Northwest. BPA occupies a unique position in the region that is crystallized in the agency`s new purpose statement: to meet their public responsibilities through commercially successful businesses. The agency must be commercially successful to provide funding for public responsibilities such as its fish and wildlife program, conservation, and reliable power and transmission systems. But the heart and soul of the agency is providing benefits that reflect the public service orientation that inspired the agency`s creation 60 years ago. BPA will provide the region with power at cost, provide preference to the region because the river on which the hydro system is based is a regional resource, and continue to see that its power flows to the little guys. It is just as important that BPA deliver power to the region`s residential and rural consumers now as it was when the agency brought electricity to rural areas for the first time.

  3. Environmental Effects of BPA

    PubMed Central

    Canesi, Laura

    2015-01-01

    Research on bisphenol A (BPA) as an environmental contaminant has now major regulatory implications toward the ecosystem health, and hence it is incumbent on scientists to do their research to the highest standards possible, in order that the most appropriate decisions are made to mitigate the impacts to aquatic wildlife. However, the contribution given so far appears rather fragmented. The present overview aims to collect available information on the effects of BPA on aquatic vertebrates and invertebrates to provide a general scenario and to suggest future developments toward more comprehensive approaches useful for aquatic species protection. PMID:26674307

  4. 77 FR 7184 - Public Availability of the National Archives and Records Administration FY 2011 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... RECORDS ADMINISTRATION Public Availability of the National Archives and Records Administration FY 2011 Service Contract Inventory AGENCY: National Archives and Records Administration. ACTION: Notice of public... Administration (NARA) is publishing this notice to advise the public of the availability of its FY 2011...

  5. 76 FR 38179 - Information Collection; General Services Administration; Information Specific to a Contract or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... ADMINISTRATION Information Collection; General Services Administration; Information Specific to a Contract or... previously approved information collection requirement regarding information specific to a contract or..., Procurement Analyst, Acquisition Policy Division, at telephone (202) 219-1813 or e-mail...

  6. 78 FR 13383 - Public Availability of the National Aeronautics and Space Administration FY 2012 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... From the Federal Register Online via the Government Publishing Office NATIONAL AERONAUTICS AND SPACE ADMINISTRATION Public Availability of the National Aeronautics and Space Administration FY 2012 Service Contract Inventory (SCI) AGENCY: Office of Procurement, National Aeronautics and...

  7. 78 FR 27239 - General Services Administration Acquisition Regulation; Submission for OMB Review; Industrial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... ADMINISTRATION General Services Administration Acquisition Regulation; Submission for OMB Review; Industrial... the Office of Management and Budget (OMB) a request to review and approve a reinstatement of a previously approved information collection requirement regarding industrial funding fee and sales...

  8. Bonneville Power Administration 1998 Annual Report.

    SciTech Connect

    United States. Bonneville Power Administration.

    1998-01-01

    This is the 1998 annual report to the President by the Administrator and Chief Executive Officer of the Bonneville Power Administration. The topics of the report include financial highlights, letter to the President, review of 1998, financial data, management`s discussion and analysis, performance measures, financial statements, BPA executives, BPA offices, BPA profile.

  9. BPA Facts Pocket Edition

    SciTech Connect

    2014-04-01

    BPA will be an engine of the Northwest’s economic prosperity and environmental sustainability. BPA’s actions advance a Northwest power system that is a national leader in providing: • high reliability; • low rates consistent with sound business principles; • responsible environmental stewardship; and • accountability to the region. We deliver on these public responsibilities through a commercially successful business.

  10. Bonneville Power Administration 1991 Annual Report.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-01-01

    Congress enacted the Bonneville Project Act in 1937, creating the Bonneville Power Administration to market and transmit the power produced by Bonneville Dam on the Columbia River. Since then, Congress has directed BPA to sell at wholesale the power produced at a total of 30 Federal dams in the Pacific Northwest, and to acquire conservation and generating resources sufficient to meet the needs of BPA`s customer utilities. The dams and the electrical system are known as the Federal Columbia River Power System. Bonneville sells wholesale power to public and private utilities, rural cooperatives, large industries, and Federal agencies. BPA also sells or exchanges power with utilities in California. BPA uses revenues from the sale of power and transmission services to recover its own expenses, to repay the Federal investment in the power system, and to pay for the resources it has acquired. BPA pays for operation and maintenance expenses at the Federal dams and at non-Federal power plants. It also pays for irrigation benefits of Federal projects allocated to power to repay, and for fish and wildlife projects which offset damage to these resources by the Federal hydropower system. This document is the 1991 statement of budget, financial statement, cash flows, capitalization, expenses, and projects. An organization chart is included.

  11. Factors that Influence Pre-Service Administrators' Views of Appropriate School Counselor Duties

    ERIC Educational Resources Information Center

    Mason, Kimberly L.; Perera-Diltz, Dilani M.

    2010-01-01

    This study surveyed pre-service administrative internship students (N = 61) at an urban Midwestern state university to explore factors that influence duties assigned to school counselors at the elementary, middle, and high school levels. Results indicated variation in duties assigned by pre-service administrators based on school building level.…

  12. 41 CFR 105-1.101 - General Services Administration Property Management Regulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-INTRODUCTION 1.1-Regulations System § 105-1.101 General Services Administration Property Management Regulations... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false General Services Administration Property Management Regulations. 105-1.101 Section 105-1.101 Public Contracts and...

  13. 75 FR 1788 - General Services Administration Acquisition Regulation; Submission for OMB Review; GSA Form 1364...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES ADMINISTRATION General Services Administration Acquisition Regulation; Submission for OMB Review; GSA Form 1364...: Under the provisions of the Paperwork Reduction Act of 1995 (44 U.S.C. Chapter 35), the General...

  14. 7 CFR 2.53 - Administrator, Food Safety and Inspection Service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Administrator, Food Safety and Inspection Service. 2... Secretary for Food Safety § 2.53 Administrator, Food Safety and Inspection Service. (a) Delegations. Pursuant to § 2.18, the following delegations of authority are made by the Under Secretary for Food...

  15. 75 FR 66796 - Pricewaterhousecoopers LLP (“PwC”), Internal Firm Services Client Account Administrators Group...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ... Services, Atlanta, Georgia. The notice was published in the Federal Register on June 7, 2010 (75 FR 32224... Account Administrators Group Atlanta, GA; Amended Certification Regarding Eligibility To Apply for Worker... PricewaterhouseCoopers LLP (``PwC''), Internal Firm Services Client Account Administrator Group, Atlanta,...

  16. Radon Monitoring Results BPA Residential Weatherization Program, Report Number 1.

    SciTech Connect

    United States. Bonneville Power Administration.

    1986-01-01

    In October 1984, the Bonneville Power Administration (BPA) began offering free radon monitoring to participants of its regionwide Residential Weatherization Program. The purpose of the radon monitoring is to provide information to participating homeowners or consumers on the average radon concentrations within their residences. This radon concentration information and other information on indoor air quality (IAQ) is provided to assist homeowners on their decision to install ''house-tightening'' weatherization measures. This radon report will present background information on why BPA decided to offer radon monitoring, the procedures used for monitoring, the extent of BPA radon monitoring in the region, and results of this monitoring. Subsequent BPA radon monitoring reports will be produced on a quarterly basis which will include a brief narrative on the radon monitoring and provide a summary of the radon data received to date.

  17. Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model

    SciTech Connect

    Yang, Xiaoxia Doerge, Daniel R.; Fisher, Jeffrey W.

    2013-07-01

    Bisphenol A (BPA) has received considerable attention throughout the last decade due to its widespread use in consumer products. For the first time a physiologically based pharmacokinetic (PBPK) model was developed in neonatal and adult rats to quantitatively evaluate age-dependent pharmacokinetics of BPA and its phase II metabolites. The PBPK model was calibrated in adult rats using studies on BPA metabolism and excretion in the liver and gastrointestinal tract, and pharmacokinetic data with BPA in adult rats. For immature rats the hepatic and gastrointestinal metabolism of BPA was inferred from studies on the maturation of phase II enzymes coupled with serum time course data in pups. The calibrated model predicted the measured serum concentrations of BPA and BPA conjugates after administration of 100 μg/kg of d6-BPA in adult rats (oral gavage and intravenous administration) and postnatal days 3, 10, and 21 pups (oral gavage). The observed age-dependent BPA serum concentrations were partially attributed to the immature metabolic capacity of pups. A comparison of the dosimetry of BPA across immature rats and monkeys suggests that dose adjustments would be necessary to extrapolate toxicity studies from neonatal rats to infant humans. - Highlights: • A PBPK model predicts the kinetics of bisphenol A (BPA) in young and adult rats. • BPA metabolism within enterocytes is required for fitting of oral BPA kinetic data. • BPA dosimetry in young rats is different than adult rats and young monkeys.

  18. Interest in Long-Term Care among Health Services Administration Students

    ERIC Educational Resources Information Center

    Temple, April; Thompson, Jon M.

    2011-01-01

    The aging of the population has created increased opportunities for health administrators in long-term care. This study consisted of a cross-sectional survey of 68 undergraduate health services administration students to explore factors related to interest in a career in long-term care administration. One third expressed interest working in the…

  19. Application of models for exchange of electronic documents in complex administrative services

    NASA Astrophysics Data System (ADS)

    Glavev, Victor

    2015-11-01

    The report presents application of models for exchange of electronic documents between different administrations in government and business sectors. It shows the benefits of implementing electronic exchange of documents between different local offices of one administration in government sector such as a municipality and the way it is useful for implementing complex administrative services.

  20. 77 FR 59790 - General Services Administration Acquisition Regulation (GSAR); Rewrite of Part 504...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... October 9, 2008, GSA published in the Federal Register at 73 FR 59589 a proposed rule with a request for... (GSAR); Rewrite of Part 504; Administrative Matters AGENCY: Office of Acquisition Policy, General... Administrative Matters and Forms. This final rule is part of the General Services Administration...

  1. 76 FR 6827 - Public Availability of the National Aeronautic and Space Administration FY 2010 Service Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ... SPACE ADMINISTRATION Public Availability of the National Aeronautic and Space Administration FY 2010 Service Contract Inventory AGENCY: National Aeronautic and Space Administration. ACTION: Notice of public... of the Consolidated Appropriations Act of 2010 (Pub. L. 111-117), National Aeronautic and...

  2. 76 FR 63509 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... CFR Part 121 RIN 3245-AG27 Small Business Size Standards: Administrative and Support, Waste Management... October 12, 2011 Part VI Small Business Administration 13 CFR Part 121 Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services; Proposed Rule #0;#0;Federal Register /...

  3. 77 FR 72691 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Part 121 RIN 3245-AG27 Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services AGENCY: U.S. Small Business Administration. ACTION: Final rule....

  4. Application of models for exchange of electronic documents in complex administrative services

    SciTech Connect

    Glavev, Victor

    2015-11-30

    The report presents application of models for exchange of electronic documents between different administrations in government and business sectors. It shows the benefits of implementing electronic exchange of documents between different local offices of one administration in government sector such as a municipality and the way it is useful for implementing complex administrative services.

  5. The School Administrator and the Food Service Program.

    ERIC Educational Resources Information Center

    Perryman, John N.

    The aim of this publication is to offer information that will assist the elementary school principal in the establishment or improvement of a school lunch program. The material focuses on the necessary ingredients of an effective school food service, the necessity of nutrition education as a part of a food service program, and the importance of…

  6. 48 CFR 42.203 - Contract administration services directory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... names and telephone numbers of those DCMA and other agency offices that offer contract administration... it on the Internet at http://www.dcma.mil/. For additional information contact—Defense...

  7. A comparative study of resident, family, and administrator expectations for service quality in nursing homes.

    PubMed

    Duffy, J A; Duffy, M; Kilbourne, W E

    2001-01-01

    This article compares the service quality expectations of residents, family, and administrators within a long-term-care context. Expectations for service quality are measured using the SERVQUAL scale. The results support the reliability of the SERVQUAL instrument for nursing home residents. Resident expectations were significantly different from administrators' expectations on all dimensions of quality. The findings are interpreted in terms of expectation formation and the nature of service encounters.

  8. A comparative study of resident, family, and administrator expectations for service quality in nursing homes.

    PubMed

    Duffy, J A; Duffy, M; Kilbourne, W E

    2001-01-01

    This article compares the service quality expectations of residents, family, and administrators within a long-term-care context. Expectations for service quality are measured using the SERVQUAL scale. The results support the reliability of the SERVQUAL instrument for nursing home residents. Resident expectations were significantly different from administrators' expectations on all dimensions of quality. The findings are interpreted in terms of expectation formation and the nature of service encounters. PMID:11482179

  9. Sustainability at BPA 2013

    SciTech Connect

    2013-12-01

    THIS IS THE THIRD YEAR BPA has reported on sustainability program accomplishments. The report provides an opportunity to review progress made on sustainability initiatives, evaluate how far we have come and how much we can improve. The program has demonstrated maturation as the concepts of sustainability and resource conservation are communicated and understood. The sustainability program started as an employee-driven “grass roots” effort in 2010. Sustainability is becoming a consideration in how work is performed. The establishment of several policies supporting sustainability efforts proves the positive progress being made. In 2009, BPA became a founder and member of The Climate Registry, a nonprofit collaboration that sets standards to calculate, verify and report greenhouse gas emissions. This year, BPA completed and published our Greenhouse Gas inventory for the years of 2009, 2010 and 2011. The 2012 inventory is currently in the process of third-party verification and scheduled for public release in January 2014. These inventories provide a concrete measure of the progress we are making.

  10. The "Special" Academic Library: Enhanced Information Services for University Committees and Administrators.

    ERIC Educational Resources Information Center

    Ensor, Pat

    This report provides information on the planning for and pilot testing of a new service called Enhanced Information Services for Administrators and Committees that was developed in 1990 by Electronic Information Services, a unit within the Reference Department of Indiana State University Libraries. The report begins with an early planning memo…

  11. Using CD-ROM to Provide Enhanced Information Services for University Administrators and Committees.

    ERIC Educational Resources Information Center

    Ensor, Pat; Hardin, Steve

    1991-01-01

    Discusses information needs of university administrators and committees, and describes the development of an information service provided by the Electronic Information Services (EIS) unit of the Indiana State University library. Highlights include staff reactions, a pilot test, marketing the service, cost effectiveness of CD-ROM use, and document…

  12. 48 CFR 7.403 - General Services Administration assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...; and (4) Industry or market trends. (b) Agencies may request information from the following GSA offices... information technology. (2) Federal Supply Service, Office of Acquisition (FC), Washington, DC 20406,...

  13. 48 CFR 7.403 - General Services Administration assistance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...; and (4) Industry or market trends. (b) Agencies may request information from the following GSA offices... information technology. (2) Federal Supply Service, Office of Acquisition (FC), Washington, DC 20406,...

  14. Master Contracting with Comprehensive Service Providers: A Tool to Simplify Administration and Promote Outcome-Focused, Integrated Services

    ERIC Educational Resources Information Center

    Lepler, Susan; Uyeda, Kimberly; Halfon, Neal

    2006-01-01

    In response to the problems caused by categorical funding for services to children and families, the National Commission on Children recommended a series of changes in the organization, administration, and implementation of programs at all levels of government, to encourage a more collaborative and comprehensive service delivery system, including…

  15. 7 CFR 2.67 - Administrator, Economic Research Service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and social science research and analyses relating to: (i) Food and agriculture situation and outlook...) Perform economic and other social science research under section 104(b)(1) and (3) of the Agricultural... Administrator, other agencies, or before the courts. (5) Review economic data and analyses used in speeches...

  16. Perceived impact by administrators of psychiatric emergency services after changes in a state's mental health system.

    PubMed

    Arfken, Cynthia L; Zeman, Lori Lackman; Koch, Alison

    2006-06-01

    As a safety net, psychiatric emergency services are sensitive to system changes. To determine the impact of a state's changes in its mental health system, administrators of publicly funded psychiatric emergency services were surveyed. They reported few (M=0.8) negative changes in coordination of care but 77% endorsed change in administrative burden (54% saying it negatively affected quality of services). Reporting negative effect of administrative burden was associated with treating more persons with substance abuse problems and greater challenge posed by distance to local providers. These results suggest that impact of state-level changes was not uniform but associated with local characteristics.

  17. 7 CFR 2.47 - Administrator, Rural Utilities Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Reauthorization Act of 1986 (42 U.S.C. 9601 et seq.). (13) Administer the Distance Learning and Medical Link... Comptroller General (4 CFR chapter II), with respect to the claims of the Rural Utilities Service. (10... Secretary by Executive Order 12580, 3 CFR, 1987 Comp., p. 193, under the following provisions of...

  18. 7 CFR 2.47 - Administrator, Rural Utilities Service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Reauthorization Act of 1986 (42 U.S.C. 9601 et seq.). (13) Administer the Distance Learning and Medical Link... Comptroller General (4 CFR chapter II), with respect to the claims of the Rural Utilities Service. (10... Secretary by Executive Order 12580, 3 CFR, 1987 Comp., p. 193, under the following provisions of...

  19. 7 CFR 2.47 - Administrator, Rural Utilities Service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Reauthorization Act of 1986 (42 U.S.C. 9601 et seq.). (13) Administer the Distance Learning and Medical Link... Comptroller General (4 CFR chapter II), with respect to the claims of the Rural Utilities Service. (10... Secretary by Executive Order 12580, 3 CFR, 1987 Comp., p. 193, under the following provisions of...

  20. 7 CFR 2.49 - Administrator, Rural Housing Service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... will provide competent and cost effective representation for the Rural Housing Service and.... 9604(i)(11)), with respect to the reduction of exposure to significant risk to human health; (iv... Rural Economic and Community Development, the following delegations are made by the Under Secretary...

  1. 78 FR 61367 - Health Resources and Services Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... comprehensive primary health care in outpatient settings for people living with HIV disease. Part D grantees...-xxxx--New. Abstract: The HRSA's HIV/AIDS Bureau (HAB) administers the Ryan White HIV/AIDS Program (RWHAP) authorized under Title XXVI of the Public Health Service Act as amended by the Ryan White...

  2. 7 CFR 2.49 - Administrator, Rural Housing Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... will provide competent and cost effective representation for the Rural Housing Service and.... 9604(i)(11)), with respect to the reduction of exposure to significant risk to human health; (iv... Rural Economic and Community Development, the following delegations are made by the Under Secretary...

  3. 76 FR 51311 - Administrative Practice and Procedure, Postal Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Postal Service's product structure has developed under the PAEA. This task is incorporated into the...). SUPPLEMENTARY HISTORY: Regulatory History: 72 FR 29284, May 25, 2007; 72 FR 33261, June 15, 2007; 72 FR 50744... (Order No. 45); see also 72 FR 63662 (November 9, 2007). The publication of the initial product...

  4. 48 CFR 42.203 - Contract administration services directory.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... services within designated geographic areas and at specified contractor plants. Federal agencies may access it on the Internet at https://pubapp.dcma.mil/CASD/main.jsp. For additional information contact... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contract...

  5. 48 CFR 42.203 - Contract administration services directory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... services within designated geographic areas and at specified contractor plants. Federal agencies may access it on the Internet at https://pubapp.dcma.mil/CASD/main.jsp. For additional information contact... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Contract...

  6. Charting a Course for the Future : BPA Programs in Perspectives, Technical Appendix.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-05-01

    Programs in Perspective is the Bonneville Power Administration`s public involvement process for engaging customers and other stakeholders in a regional dialog to set strategic direction and broad program plans for BPA. This process leads into a biennial rate setting cycle and offers a more accessible and flexible opportunity for dialog on broad issues than is possible under the strict administrative procedures of ratemaking. The self-financed character of BPA has made this public process a necessary and valuable one to assure that those who play BPA`s rates have a clear understanding and a strong voice in the plans for use of the resulting revenues.

  7. Blood Donor Locator Service--Social Security Administration. Final rules.

    PubMed

    1991-12-24

    We are issuing these final regulations to govern the Blood Donor Locator Service, which we will establish and conduct, as required by section 8008 of the Technical and Miscellaneous Revenue Act of 1988 (Pub. L. 100-647). Under these regulations, we will furnish to participating States at their request the last known personal mailing address (residence or post office box) of blood donors whose blood donation shows that they are or may be infected with the human immunodeficiency virus (HIV) which causes acquired immune deficiency syndrome, if the State or an authorized blood donation facility has been unable to locate the donors. If our records or those of the Internal Revenue Service (IRS) contain an adequate personal mailing address for the donor, we will provide it to the State so that the State or the blood donation facility can inform the donor that he or she may need medical care and treatment. PMID:10116070

  8. [Optimal exchange of resources and the administration of bibliographical services].

    PubMed

    Myatt, A G

    1981-01-01

    It is pointed out in this paper that an optimal exchange of resources requires a maximum availability of materials and services at minimum cost. The author is of the view that each activity of the biomedical information network will have to be subjected to critical scrutiny including a calculation of its costs. The overall plan will determine whether current activities can be maintained or expanded and new activities launched. The primary given to access to materials rather than to their possession is a step toward user-oriented networks, and therefore means that future development will be assessed in relation to the customer. The author is convinced that the recording and analysis of the use actually made of services by the user will generate many of the criteria that will govern some of the most important decisions to be taken in the future in connection with the network. PMID:7308118

  9. BPA Instream Habitat Projects Completed within Asotin Creek Watershed, 1999-2001 Final Report.

    SciTech Connect

    Johnson, Bradley J.

    2002-10-23

    The Asotin County Conservation District (ACCD) is the primary entity coordinating habitat projects on both private and public lands within the Asotin Creek watershed. The watershed covers approximately 325 square miles in the Blue Mountains of southeastern Washington in WRIA 35. According to WDFW's Priority WRIA's by At-Risk Stock Significance Map, it is the highest priority WRIA in southeastern WA. Summer steelhead, bull trout, and Snake River spring chinook salmon which are listed under the Endangered Species Act (ESA), are present in the watershed. WDFW manages it as a Wild Steelhead Reserve, because no hatchery fish have been released here since 1997. The ACCD has been working with landowners, Bonneville Power Administration (BPA), Washington State Conservation Commission (WCC), Natural Resource Conservation Service (NRCS), Washington Department of Fish and Wildlife (WDFW), U.S. Forest Service, Pomeroy Ranger District (USFS), Nez Perce Tribe (NPT), Department of Ecology (DOE), National Marine Fisheries Service (NMFS), and U.S. Fish and Wildlife Service (USFWS) to address habitat projects in Asotin County. Local students, volunteers and Salmon Corps Members have been instrumental in the success of the Model Watershed Program on Asotin Creek. ACCD began coordinating habitat projects in 1995 with the help of BPA funding. Approximately two hundred seventy-six projects have been implemented as of 1999. The Washington State Legislature was successful in securing funding for endangered salmon and steelhead recovery throughout the State in 1998. While these issues were new to most of the State, southeastern Washington had been dealing with endangered fall and spring chinook salmon since 1994. The Asotin Creek In-Stream Habitat Project teamed BPA and Governor's Salmon Recovery Funding on four instream habitat projects in the Asotin Creek Watershed. These projects provide complex instream habitat for steelhead, bull trout and spring chinook in the stream. 38 pools were

  10. Artificial intelligence in the service of system administrators

    NASA Astrophysics Data System (ADS)

    Haen, C.; Barra, V.; Bonaccorsi, E.; Neufeld, N.

    2012-12-01

    The LHCb online system relies on a large and heterogeneous IT infrastructure made from thousands of servers on which many different applications are running. They run a great variety of tasks: critical ones such as data taking and secondary ones like web servers. The administration of such a system and making sure it is working properly represents a very important workload for the small expert-operator team. Research has been performed to try to automatize (some) system administration tasks, starting in 2001 when IBM defined the so-called “self objectives” supposed to lead to “autonomic computing”. In this context, we present a framework that makes use of artificial intelligence and machine learning to monitor and diagnose at a low level and in a non intrusive way Linux-based systems and their interaction with software. Moreover, the multi agent approach we use, coupled with an “object oriented paradigm” architecture should increase our learning speed a lot and highlight relations between problems.

  11. 75 FR 1788 - General Services Administration Regulation; Submission for OMB Review; Packing List Clause

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... comments was published in the Federal Register at 74 FR 52811, October 14, 2009. No comments were received... Administration, 1800 F Street, NW., Room 4041, Washington, DC 20405. Please cite OMB Control No. 3090-0246... General Services Administration, Regulatory Secretariat (MVPR), 1800 F Street, NW., Room 4041,...

  12. 77 FR 2726 - General Services Administration Acquisition Regulation; Information Collection; Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... ADMINISTRATION General Services Administration Acquisition Regulation; Information Collection; Contract Financing... 1142 was inadvertently deleted as part of the rewrite of GSAR regulations on Contract Financing. GSA... Information Collection 3090- 0080, Contract Financing Final Payment; (GSAR Part 532 and 552.232-72; GSA...

  13. 77 FR 15370 - General Services Administration Acquisition Regulation; Information Collection; Price Reductions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... date of the notice of request for comments regarding OMB Control No. 3090-0235, Price Reductions Clause, published in the Federal Register at 76 FR 81941, on December 29, 2011. DATES: Submit comments on or before... ADMINISTRATION General Services Administration Acquisition Regulation; Information Collection; Price...

  14. 77 FR 58380 - General Services Administration Acquisition Regulation; Submission for OMB Review; Price...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... ADMINISTRATION General Services Administration Acquisition Regulation; Submission for OMB Review; Price... collection requirement regarding the GSAR Price Reductions Clause. A notice was published in the Federal Register at 76 FR 89141, on December 29, 2011. One respondent submitted comments. Public comments...

  15. 75 FR 48872 - General Services Administration Acquisition Regulation; Rewrite of GSAR Part 541, Acquisition of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... must provide that the limit can only be increased by affirmative action of the Government. Comment: The... Administration (GSA). ACTION: Final rule. SUMMARY: The General Services Administration (GSA) is amending the... Federal Register at 71 FR 7910, an Advanced Notice of Proposed Rulemaking (ANPR) with a request...

  16. 75 FR 66797 - PricewaterhouseCoopers LLP (“PwC”) Internal Firm Services Client Account Administrators Group...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ... Employment and Training Administration PricewaterhouseCoopers LLP (``PwC'') Internal Firm Services Client... read PricewaterhouseCoopers LLP (``PwC''), Internal Firm Services Client Account Administrators Group... PricewaterhouseCoopers LLP (``PwC''), Internal Firm Services Client Account Administrators Group. The...

  17. 10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... for Information Services and Administration and Chief Information Officer. (a) The Deputy Executive Director for Information Services and Administration and Chief Information Officer, on the basis of...

  18. 76 FR 5647 - Public Availability of U.S. Small Business Administration FY 2010 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-01

    ... ADMINISTRATION Public Availability of U.S. Small Business Administration FY 2010 Service Contract Inventory AGENCY: U.S. Small Business Administration. ACTION: Notice of Public Availability of FY 2010 Service... Appropriations Act of 2010 (Pub. L. 111-117), the Small Business Administration is publishing this notice...

  19. 77 FR 22831 - Public Availability of U.S. Small Business Administration FY 2010 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... ADMINISTRATION Public Availability of U.S. Small Business Administration FY 2010 Service Contract Inventory AGENCY: U.S. Small Business Administration. ACTION: Notice of Public Availability of FY 2011 Service... Appropriations Act of 2010 (Pub. L. 111-117), the Small Business Administration is publishing this notice...

  20. 78 FR 16563 - Public Availability of U.S. Small Business Administration FY 2012 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... ADMINISTRATION Public Availability of U.S. Small Business Administration FY 2012 Service Contract Inventory AGENCY: U.S. Small Business Administration. ACTION: Notice of Public Availability of FY 2012 Service... Appropriations Act of 2010 (Pub. L. 111-117), the Small Business Administration is publishing this notice...

  1. 28 CFR 0.157 - Federal Bureau of Investigation-Drug Enforcement Administration Senior Executive Service.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... position in the excepted service does not include: (1) A Schedule C position authorized under 5 CFR 213... within the Federal Bureau of Investigation (FBI) and the Drug Enforcement Administration (DEA) to be known as the FBI-DEA Senior Executive Service (FBI-DEA SES). (b) Pursuant to 5 U.S.C. 3151(b)(2)(B),...

  2. 28 CFR 0.157 - Federal Bureau of Investigation-Drug Enforcement Administration Senior Executive Service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... position in the excepted service does not include: (1) A Schedule C position authorized under 5 CFR 213... within the Federal Bureau of Investigation (FBI) and the Drug Enforcement Administration (DEA) to be known as the FBI-DEA Senior Executive Service (FBI-DEA SES). (b) Pursuant to 5 U.S.C. 3151(b)(2)(B),...

  3. 28 CFR 0.157 - Federal Bureau of Investigation-Drug Enforcement Administration Senior Executive Service.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... position in the excepted service does not include: (1) A Schedule C position authorized under 5 CFR 213... within the Federal Bureau of Investigation (FBI) and the Drug Enforcement Administration (DEA) to be known as the FBI-DEA Senior Executive Service (FBI-DEA SES). (b) Pursuant to 5 U.S.C. 3151(b)(2)(B),...

  4. 28 CFR 0.157 - Federal Bureau of Investigation-Drug Enforcement Administration Senior Executive Service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... position in the excepted service does not include: (1) A Schedule C position authorized under 5 CFR 213... within the Federal Bureau of Investigation (FBI) and the Drug Enforcement Administration (DEA) to be known as the FBI-DEA Senior Executive Service (FBI-DEA SES). (b) Pursuant to 5 U.S.C. 3151(b)(2)(B),...

  5. 28 CFR 0.157 - Federal Bureau of Investigation-Drug Enforcement Administration Senior Executive Service.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... position in the excepted service does not include: (1) A Schedule C position authorized under 5 CFR 213... within the Federal Bureau of Investigation (FBI) and the Drug Enforcement Administration (DEA) to be known as the FBI-DEA Senior Executive Service (FBI-DEA SES). (b) Pursuant to 5 U.S.C. 3151(b)(2)(B),...

  6. 42 CFR 484.14 - Condition of participation: Organization, services, and administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Standard: Services furnished. Part-time or intermittent skilled nursing services and at least one other... personnel, and the staff; employs qualified personnel and ensures adequate staff education and evaluations... administrator. (d) Standard: Supervising physician or registered nurse. The skilled nursing and...

  7. 42 CFR 484.14 - Condition of participation: Organization, services, and administration.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Standard: Services furnished. Part-time or intermittent skilled nursing services and at least one other... personnel, and the staff; employs qualified personnel and ensures adequate staff education and evaluations... administrator. (d) Standard: Supervising physician or registered nurse. The skilled nursing and...

  8. A Qualitative Assessment Project Comparing and Contracting Faculty and Administrators' Perspectives on Service-Learning

    ERIC Educational Resources Information Center

    Welch, Marshall; Liese, Lawrence H.; Bergerson, Amy

    2004-01-01

    More than 130 service-learning courses have been developed and taught at the University of Utah, a major Research I university, over the last ten years. A series of focus groups were conducted to identify salient factors related to faculty and administrators' perspectives of the advantages and challenges associated with service-learning. The study…

  9. The Relationship between Institutional Unit and Administrative Features of Disability Services Offices in Higher Education

    ERIC Educational Resources Information Center

    Harbour, Wendy S.

    2009-01-01

    Using data from an Association on Higher Education And Disability (AHEAD) survey, this study of 424 postsecondary disability services (DS) administrators examines how campus and office characteristics may vary with disability services placement in academic or student affairs. The results of this survey suggest that only modest differences exist,…

  10. 77 FR 72868 - The Centers for Disease Control (CDC)/Health Resources and Services Administration (HRSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... HUMAN SERVICES Centers for Disease Control and Prevention The Centers for Disease Control (CDC)/Health Resources and Services Administration (HRSA) Advisory Committee on HIV, Viral Hepatitis and STD Prevention... (Pub. L. 92-463) of October 6, 1972, that the CDC/HRSA Advisory Committee on HIV, Viral Hepatitis...

  11. Receipt of employment services among Veterans Health Administration users with psychiatric diagnoses.

    PubMed

    Abraham, Kristen M; Ganoczy, Dara; Yosef, Matheos; Resnick, Sandra G; Zivin, Kara

    2014-01-01

    This study examined the population-based reach of Veterans Health Administration (VHA) employment services to VHA patients with psychiatric diagnoses. Reach of services includes the percentage and characteristics of people who accessed services compared with those who did not. Using clinical administrative data, we identified patients with a psychiatric diagnosis among a random sample of all patients who received VHA services in 1 yr. Among VHA patients with psychiatric diagnoses, we examined their likelihood of receiving any VHA employment services and specific types of employment services, including supported employment, transitional work, incentive therapy, and vocational assistance. We identified clinical and demographic characteristics associated with receiving employment services. Results indicated that 4.2% of VHA patients with a psychiatric diagnosis received employment services. After adjusting for clinical and demographic characteristics, VHA patients with schizophrenia and bipolar disorder were more likely to receive any employment services and to receive supported employment than were patients with depression, PTSD, or other anxiety disorders. VHA patients with depression and PTSD were more likely to receive transitional work and vocational assistance than patients with schizophrenia. Future studies should examine system-level barriers to receiving employment services and identify types of employment services most appropriate for Veterans with different psychiatric diagnoses.

  12. 7. Photocopy of Elevations drawing (from the BPA Engineering Vault, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of Elevations drawing (from the BPA Engineering Vault, Drawing C13-J2-342-D1, Sheet 3, 13 March 1939) - Bonneville Power Administration South Bank Substation, I-84, South of Bonneville Dam Powerhouse, Bonneville, Multnomah County, OR

  13. 9. Photocopy of Reinforced Concrete Details drawing (from the BPA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopy of Reinforced Concrete Details drawing (from the BPA Engineering Vault, Drawing C13-J2-342-D1, Sheet 6, 13 March 1939) - Bonneville Power Administration South Bank Substation, I-84, South of Bonneville Dam Powerhouse, Bonneville, Multnomah County, OR

  14. BPA`s large customers seek new suppliers

    SciTech Connect

    1994-06-06

    Large customers are seeking to reduce dependence on the Bonneville Power Administration by buying power from alternative sources. BPA raised rates an average of 15.7% last October and may impose a 10% one-year surcharge in October because of costs associated with protecting endangered salmon.

  15. Rates and correlates of tobacco cessation service use nationally in the Veterans Health Administration.

    PubMed

    Kelly, Megan M; Sido, Hannah; Rosenheck, Robert

    2016-05-01

    Tobacco use is a substantial problem for veterans using Veterans Health Administration (VHA) services, but relatively little is known about the association of specific patient characteristics, patterns of service use, the amount of such services, and the frequency of their use. Analysis of national VHA administrative data (N = 5,531,379) from fiscal year 2012 (FY2012) were used to identify use of tobacco cessation counseling services among veterans with a diagnosed tobacco use disorder, and to examine correlates of such use. Only 3.8% of veterans diagnosed with a tobacco use disorder used VHA tobacco cessation services, and only 0.9% met U.S. Public Health Service clinical practice guidelines for the recommended amount of counseling (i.e., 4 or more sessions). Veterans who used intensive tobacco cessation counseling services were more likely to be homeless, had comorbid mental health and substance use disorders, and used more VHA services overall than veterans who did not use tobacco cessation services. An analysis of the supply of tobacco cessation services (counseling visits provided per 100 veteran users of any services at each facility) showed that increasing the supply by just 1 visit for every 100 veterans would increase the percentage of veterans involved in tobacco cessation counseling by 35%. Veterans diagnosed with tobacco use disorder substantially underuse VHA tobacco cessation counseling services, and use is greatest at facilities that provide more tobacco cessation counseling services. Future efforts should focus on increasing the amount of VHA tobacco cessation services and encouraging veterans' awareness of and motivation to use these services. (PsycINFO Database Record PMID:27148953

  16. Provide Systematic Guidance Services. Module LT-C-2 of Category C--Student Services. Competency-Based Vocational Education Administrator Module Series.

    ERIC Educational Resources Information Center

    Puleo, Nancy F.; And Others

    This module, one in a series of competency-based administrator instructional packages, focuses on a specific competency that vocational education administrators need to be successful in the area of student services. The purpose of the module is to help the administrator develop skill in defining the broad conceptualization of student services,…

  17. 47 CFR 54.725 - Universal service disbursements during pendency of a request for review and Administrator decision.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Universal service disbursements during pendency of a request for review and Administrator decision. 54.725 Section 54.725 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator §...

  18. 76 FR 76980 - Notice of Listing of Members of the Food and Drug Administration's Senior Executive Service...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... be named to serve on FDA's Senior Executive Performance Review Board or Panels, which oversee the evaluation of performance appraisals of FDA's Senior Executive Service (SES) members. The Civil Service... Administration's Senior Executive Service Performance Review Board AGENCY: Food and Drug Administration,...

  19. 12 CFR 1808.606 - Program Administrator; Servicer; Master Servicer/Trustee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Managing regional or national originator communication systems and infrastructure; (v) Developing and...) Managing regional or national intake, processing, or servicing operational systems and infrastructure of... Bond Loans; (ii) Financial strength and capacity; (iii) Managing regional or national...

  20. Final priority; Rehabilitation Services Administration--Assistive Technology Alternative Financing Program. Final priority.

    PubMed

    2014-08-14

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Assistive Technology Alternative Financing Program administered by the Rehabilitation Services Administration (RSA). The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. This priority is designed to ensure that the Department funds high-quality assistive technology (AT) alternative financing programs (AFPs) that meet rigorous standards in order to enable individuals with disabilities to access and acquire assistive technology devices and services necessary to achieve education, community living, and employment goals.

  1. Global positioning system applications at the Bonneville Power Administration

    SciTech Connect

    Street, M.A.; Thurein, I.P.; Martin, K.E.

    1995-12-31

    The Bonneville Power Administration (BPA) has used the precise timing feature of the Global Positioning System (GPS) to enhance power system performance and reliability. The BPA Traveling Wave Fault Locator System and the BPA Phasor Measurement System both employ GPS timing.

  2. 48 CFR 908.7101-2 - Consolidated acquisition of new vehicles by General Services Administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Management Regulations (DOE-PMR) 41 CFR 109-26.501. Orders for all motor vehicles must be placed utilizing... submitted utilizing GSA's on-line system (Auto Choice), in accordance with FPMR 41 CFR 101-26.501... Services Administration. (a) New vehicles shall be procured in accordance with Federal Property...

  3. 48 CFR 908.7101-2 - Consolidated acquisition of new vehicles by General Services Administration.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Management Regulations (DOE-PMR) 41 CFR 109-26.501. Orders for all motor vehicles must be placed utilizing... submitted utilizing GSA's on-line system (Auto Choice), in accordance with FPMR 41 CFR 101-26.501... Services Administration. (a) New vehicles shall be procured in accordance with Federal Property...

  4. Substance Abuse and Mental Health Services Administration. March/April 2008

    ERIC Educational Resources Information Center

    Goodman, Deborah, Ed.

    2008-01-01

    "SAMHSA News" is the national newsletter of the Substance Abuse and Mental Health Services Administration. Published six times a year (bimonthly) by SAMHSA's Office of Communications, SAMHSA News contains information about the latest substance abuse and mental health treatment and prevention practices, recent statistics on mental health and…

  5. HIGHER EDUCATION IN THE NATION'S FIRE SERVICE, INTERNATIONAL FIRE ADMINISTRATION INSTITUTE.

    ERIC Educational Resources Information Center

    State Univ. of New York, Albany. Center for Executive Development.

    THIS PUBLICATION IS A REVISED AND UP-DATED EDITION OF A PUBLICATION, "FIRE SERVICE TECHNOLOGY CURRICULA SURVEY," BASED ON A SURVEY CONDUCTED IN 1966 BY THE INTERNATIONAL FIRE ADMINISTRATION INSTITUTE FOR THE PURPOSE OF ASCERTAINING THE SCOPE OF THE FIRE EDUCATION PROGRAMS IN THE NATION'S INSTITUTIONS OF HIGHER LEARNING. A DIRECTORY OF INSTITUTIONS…

  6. Required Preliminary Administrative Service Credential Program Culminating Activities in California NCATE Accredited Universities

    ERIC Educational Resources Information Center

    Wildman, Louis

    2014-01-01

    The purpose of this effort is to share information about the variety of culminating activities used in the acquisition of the California Preliminary Administrative Services Credential. Knowledge of these varying culminating activities and related practices has not previously been readily available. The culminating activities among…

  7. 78 FR 57156 - General Services Administration Acquisition Regulation; Submission for OMB Review; Modifications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... Acquisition Policy Division, GSA, 202-357-9652 or email Dana.Munson@gsa.gov for clarification of content. For... Services Administration, Regulatory Secretariat Division (MVCB), 2250C, 1800 F Street NW., Washington, DC...-72 Modifications (Multiple Award Schedule), is being reinstated at GSAR 552.238-81,...

  8. 9 CFR 72.18 - Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (SPLENETIC) FEVER IN CATTLE § 72.18 Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment required when dipping facilities unavailable. (a) Tick-infested cattle. Cattle of the free area which are tick-infested may be moved interstate for any purpose after they...

  9. 9 CFR 72.18 - Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (SPLENETIC) FEVER IN CATTLE § 72.18 Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment required when dipping facilities unavailable. (a) Tick-infested cattle. Cattle of the free area which are tick-infested may be moved interstate for any purpose after they...

  10. 9 CFR 72.18 - Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (SPLENETIC) FEVER IN CATTLE § 72.18 Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment required when dipping facilities unavailable. (a) Tick-infested cattle. Cattle of the free area which are tick-infested may be moved interstate for any purpose after they...

  11. A Course in Administration for Managers of Information Services: Design, Implementation and Topical Outline.

    ERIC Educational Resources Information Center

    Wasserman, Paul; Rizzo, John R.

    A topical outline for courses in administration for managers of information services, and a set of guidelines for designing and implementing these courses are included in this manual for those responsible for planning, developing, and offering management training programs. Key elements in presenting and developing management skills of information…

  12. 7 CFR 2.53 - Administrator, Food Safety and Inspection Service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... or her authority, exercise the functions delegated to the Secretary by Executive Order 12580, 3 CFR... to the Administrator, Food Safety and Inspection Service: (1) Exercise the functions of the Secretary... and other products. (2) Exercise the functions of the Secretary of Agriculture contained in...

  13. 7 CFR 2.53 - Administrator, Food Safety and Inspection Service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... or her authority, exercise the functions delegated to the Secretary by Executive Order 12580, 3 CFR... to the Administrator, Food Safety and Inspection Service: (1) Exercise the functions of the Secretary... and other products. (2) Exercise the functions of the Secretary of Agriculture contained in...

  14. 7 CFR 2.53 - Administrator, Food Safety and Inspection Service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... or her authority, exercise the functions delegated to the Secretary by Executive Order 12580, 3 CFR... to the Administrator, Food Safety and Inspection Service: (1) Exercise the functions of the Secretary... and other products. (2) Exercise the functions of the Secretary of Agriculture contained in...

  15. 77 FR 53802 - Procurement, Management, and Administration of Engineering and Design Related Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... Register of August 30, 2010 (75 FR 53129), and effective on October 1, 2010, raising the Federal simplified... specified in the final rule published in the Federal Register of August 30, 2010 (75 FR 53129)). Additional... of Engineering and Design Related Services AGENCY: Federal Highway Administration (FHWA),...

  16. College and University Dining Services Administrators' Intention to Adopt Sustainable Practices: Results from US Institutions

    ERIC Educational Resources Information Center

    Chen, Chao-Jung; Gregoire, Mary B.; Arendt, Susan; Shelley, Mack C.

    2011-01-01

    Purpose: The purpose of this paper is to examine college and university dining services administrators' (CUDSAs) intention to adopt sustainable practices. Design/methodology/approach: The theory of planned behavior (TPB) including constructs of subjective norm (SN), attitude, perceived behavior control, and personal norm (PN), formed the…

  17. Views of School Administrators Related to In-Service Training Activities

    ERIC Educational Resources Information Center

    Güngör, Semra Kiranli; Yildirim, Yusuf

    2016-01-01

    The aim of this research is to specify the views of school administrators related to in-service training activities. In this research, semi-structured interview method, one of the qualitative research methods, has been used. Content analysis has been used in order to analyze the interview data and themes and sub-themes have been constituted. The…

  18. 7 CFR 2.53 - Administrator, Food Safety and Inspection Service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administrator, Food Safety and Inspection Service. 2.53 Section 2.53 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY THE SECRETARY OF AGRICULTURE AND GENERAL OFFICERS OF THE DEPARTMENT Delegations of Authority by the...

  19. Business Services' Impact on Student Retention: Exploring Student and Administrator Perceptions

    ERIC Educational Resources Information Center

    Hassabis, Haris

    2014-01-01

    High student attrition rates for first-year university students affect the financial and long-term sustainability of institutions. Previous researchers failed to provide workable solutions to improving student retention. This study was an exploration of students' and administrators' perceptions of business services and their potential impact on…

  20. CCSF Survey on Using Technology: Administrators, Department Chairs, Classified Staff, and Student Services.

    ERIC Educational Resources Information Center

    City Coll. of San Francisco, CA. Office of Institutional Research, Planning and Grants.

    This document discusses the findings of a survey completed by all employees of City College of San Francisco in 2003. The employees surveyed include administrators, department chairs, classified staff, and student service faculty. The survey discovered that these employees differ from instructional faculty in the following ways: (1) they do their…

  1. 32 CFR 644.314 - Rules and regulations of the General Services Administration (GSA).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Rules and regulations of the General Services Administration (GSA). 644.314 Section 644.314 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal § 644.314 Rules and regulations...

  2. 32 CFR 644.314 - Rules and regulations of the General Services Administration (GSA).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Rules and regulations of the General Services Administration (GSA). 644.314 Section 644.314 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal § 644.314 Rules and regulations...

  3. 32 CFR 644.524 - Reporting contaminated land to the General Services Administration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Reporting contaminated land to the General... and Other Contamination from Proposed Excess Land and Improvements § 644.524 Reporting contaminated land to the General Services Administration. Contaminated areas, except industrial properties...

  4. A&M. Technical service laboratory in administration building (TAN602). Floor plan, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Technical service laboratory in administration building (TAN-602). Floor plan, reception desk, door and finish schedules. Ralph M. Parsons 1480-12-ANP/GE-3-602-A-1. INEEL index code no. 033-0602-00-693-107488 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  5. 77 FR 5253 - Public Availability of General Services Administration FY 2011 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... CONTACT: Questions regarding the service contract inventory should be directed to Mr. Paul F. Boyle in the Office of Acquisition Policy at (202) 501-0324 or via email to paul.boyle@gsa.gov . SUPPLEMENTARY... Act Public Law 111-117, GSA is publishing this notice to advise the public of the availability of...

  6. 78 FR 10174 - Public Availability of General Services Administration FY 2012 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... Appropriations Act Public Law 111-117, GSA is publishing this notice to advise the public of the availability of...: Questions regarding the service contract inventory should be directed to Mr. Paul F. Boyle in the Office of Acquisition Policy at 202-501-0324 or Paul.Boyle@gsa.gov . SUPPLEMENTARY INFORMATION: In accordance...

  7. Review of BPA Funded Sturgeon, Resident Fish and Wildlife Projects for 1990/1991.

    SciTech Connect

    United States. Bonneville Power Administration.

    1990-12-01

    The Bonneville Power Administration (BPA) held a public meeting on November 19--21, 1991, for the purpose of review, coordination, and consultation of the BPA-funded projects for sturgeon, resident fish, and wildlife in the Columbia River Basin (Basin). The comments received after the meeting were favorable and the participants agreed that the meeting was stimulating and productive. The information exchanged should lead to better coordination with other projects throughout the Basin. This document list the projects by title, the project leaders and BPA's project officers, and an abstract of each leader's presentation.

  8. Administrative Coordination in Non-Profit Human Service Delivery Networks: The Role of Competition and Trust

    PubMed Central

    Bunger, Alicia C.

    2014-01-01

    Non-profit human service organizations operating within the same regional network are often faced with dual pressure to compete as well as coordinate administrative operations (by sharing funding, staff or space) to enhance efficiency. Emerging evidence has demonstrated that competing organizations coordinate, despite the risks. Trust, or perceived trustworthiness between two organizations may mitigate the negative influence of competition on coordination, however there have been few explicit tests of this hypothesis among non-profit organizations. Drawing on quantitative data collected from a network of 36 non-profit children’s behavioral health organizations, this paper empirically tests how competition and perceived trustworthiness interact to influence administrative coordination. Results support the hypothesis that trustworthiness moderates the influence of competition on administrative coordination. Findings suggest that as competing non-profit leaders build trust, the more their agencies coordinate their administrative functions. This study highlights the importance of leaders’ perceptions for organizational strategy. PMID:25349468

  9. Administrative Coordination in Non-Profit Human Service Delivery Networks: The Role of Competition and Trust.

    PubMed

    Bunger, Alicia C

    2013-12-01

    Non-profit human service organizations operating within the same regional network are often faced with dual pressure to compete as well as coordinate administrative operations (by sharing funding, staff or space) to enhance efficiency. Emerging evidence has demonstrated that competing organizations coordinate, despite the risks. Trust, or perceived trustworthiness between two organizations may mitigate the negative influence of competition on coordination, however there have been few explicit tests of this hypothesis among non-profit organizations. Drawing on quantitative data collected from a network of 36 non-profit children's behavioral health organizations, this paper empirically tests how competition and perceived trustworthiness interact to influence administrative coordination. Results support the hypothesis that trustworthiness moderates the influence of competition on administrative coordination. Findings suggest that as competing non-profit leaders build trust, the more their agencies coordinate their administrative functions. This study highlights the importance of leaders' perceptions for organizational strategy.

  10. Designing the Expanded Programme on Immunisation (EPI) as a service: Prioritising patients over administrative logic.

    PubMed

    McKnight, Jacob; Holt, Douglas B

    2014-01-01

    Expanded Programme on Immunisation (EPI) vaccination rates remain well below herd immunity in regions of many countries despite huge international resources devoted to both financing and access. We draw upon service marketing theory, organisational sociology, development anthropology and cultural consumer research to conduct an ethnographic study of vaccination delivery in Jimma Zone, Ethiopia - one such region. We find that Western public health sector policies are dominated by an administrative logic. Critical failures in delivery are produced by a system that obfuscates the on-the-ground problems that mothers face in trying to vaccinate their children, while instead prioritising administrative processes. Our ethnographic analysis of 83 mothers who had not vaccinated their children reveals key barriers to vaccination from a 'customer' perspective. While mothers value vaccination, it is a 'low involvement' good compared to the acute daily needs of a subsistence life. The costs imposed by poor service - such as uncaring staff with class hostilities, unpredictable and missed schedules and long waits - are too much and so they forego the service. Our service design framework illuminates specific service problems from the mother's perspective and points towards simple service innovations that could improve vaccination rates in regions that have poor uptake. PMID:25363481

  11. Designing the Expanded Programme on Immunisation (EPI) as a service: Prioritising patients over administrative logic.

    PubMed

    McKnight, Jacob; Holt, Douglas B

    2014-01-01

    Expanded Programme on Immunisation (EPI) vaccination rates remain well below herd immunity in regions of many countries despite huge international resources devoted to both financing and access. We draw upon service marketing theory, organisational sociology, development anthropology and cultural consumer research to conduct an ethnographic study of vaccination delivery in Jimma Zone, Ethiopia - one such region. We find that Western public health sector policies are dominated by an administrative logic. Critical failures in delivery are produced by a system that obfuscates the on-the-ground problems that mothers face in trying to vaccinate their children, while instead prioritising administrative processes. Our ethnographic analysis of 83 mothers who had not vaccinated their children reveals key barriers to vaccination from a 'customer' perspective. While mothers value vaccination, it is a 'low involvement' good compared to the acute daily needs of a subsistence life. The costs imposed by poor service - such as uncaring staff with class hostilities, unpredictable and missed schedules and long waits - are too much and so they forego the service. Our service design framework illuminates specific service problems from the mother's perspective and points towards simple service innovations that could improve vaccination rates in regions that have poor uptake.

  12. 47 CFR 54.806 - Calculation by the Administrator of interstate access universal service support for areas served...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... access universal service support for areas served by price cap local exchange carriers. 54.806 Section 54...) UNIVERSAL SERVICE Interstate Access Universal Service Support Mechanism § 54.806 Calculation by the Administrator of interstate access universal service support for areas served by price cap local...

  13. Hospital administration team development and support in a children's cancer service.

    PubMed

    Slater, Penelope J

    2011-11-01

    The administration team in the Queensland Children's Cancer Centre at the Royal Children's Hospital, Brisbane, included a team of 16 administration staff supporting the service and the state-wide clinical network. Shortly after the creation of a new expanded service, issues became apparent in administration team morale, relationships, communication, processes, leadership, support and training. The analysis of these issues included team interviews and surveys, consultation with senior administration staff and monthly sick leave monitoring. Strategies implemented included providing information; the joint development of a team business plan and individual performance plans; a review of the team's structure, workload and business processes; engaging staff in quality improvements; and the development of relationships and leadership. As a result, the team reported being more comfortable and supported in their roles, had improved morale and worked better together with more consistent and improving business processes. They had clear purpose and expectations of their roles, displayed better customer service and had reduced sick leave. The study shows that in a high stress environment, such as a children's cancer centre, attention to the team's culture, vision and purpose, providing information and improving communication and relationships, when combined with a team's enthusiasm, will improve the team's growth, cooperation and work outcomes.

  14. Pathways to vocational services: factors affecting entry by veterans enrolled in Veterans Health Administration mental health services.

    PubMed

    Drebing, Charles E; Mueller, Lisa; Van Ormer, E Alice; Duffy, Patricia; LePage, James; Rosenheck, Robert; Drake, Robert; Rose, Gary S; King, Kendra; Penk, Walter

    2012-02-01

    The current study provides naturalistic data documenting the pathways-to-care to vocational services for 155 veterans who were receiving some form of mental health care from the Veterans Health Administration and had a vocational need but were not currently enrolled in vocational services. Of the participants, 94.2% had recognized their vocational need, 80.6% reported that they or someone else had sought help to alleviate the need, and 77.4% had previously received some form of vocational services. The median length of the participants' vocational need was more than 4.2 years. Delays associated with recognition, help-seeking, and treatment entry all contributed to the overall delay in entering appropriate care. Filtering factors associated with quicker recognition, seeking help, and receiving services included diagnosis, level of disability, type of vocational need, and support from primary providers, family, and friends. The results provide information for designing interventions to improve service entry by adults with mental health problems and vocational needs.

  15. Substance Abuse and Mental Health Services Administration (SAMHSA) Behavioral Health Disaster Response App.

    PubMed

    Seligman, Jamie; Felder, Stephanie S; Robinson, Maryann E

    2015-10-01

    The Substance Abuse and Mental Health Services Administration (SAMHSA) in the Department of Health and Human Services offers extensive disaster behavior health resources to assist disaster survivors in preparing for, responding to, and recovering from natural and manmade disasters. One of SAMHSA's most innovative resources is the SAMHSA Behavioral Health Disaster Response App (SAMHSA Disaster App). The SAMHSA Disaster App prepares behavioral health responders for any type of traumatic event by allowing them to access disaster-related materials and other key resources right on their phone, at the touch of a button. The SAMHSA Disaster App is available on iPhone, Android, and BlackBerry devices. PMID:26165522

  16. Substance Abuse and Mental Health Services Administration (SAMHSA) Behavioral Health Disaster Response App.

    PubMed

    Seligman, Jamie; Felder, Stephanie S; Robinson, Maryann E

    2015-10-01

    The Substance Abuse and Mental Health Services Administration (SAMHSA) in the Department of Health and Human Services offers extensive disaster behavior health resources to assist disaster survivors in preparing for, responding to, and recovering from natural and manmade disasters. One of SAMHSA's most innovative resources is the SAMHSA Behavioral Health Disaster Response App (SAMHSA Disaster App). The SAMHSA Disaster App prepares behavioral health responders for any type of traumatic event by allowing them to access disaster-related materials and other key resources right on their phone, at the touch of a button. The SAMHSA Disaster App is available on iPhone, Android, and BlackBerry devices.

  17. 41 CFR 102-118.420 - Can the Administrator of General Services waive the postpayment auditing provisions of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Can the Administrator of General Services waive the postpayment auditing provisions of this subpart? 102-118.420 Section 102-118... Transportation Audits § 102-118.420 Can the Administrator of General Services waive the postpayment...

  18. [Alcohol consumption in administrative and service personnel in an Ecuadorian university].

    PubMed

    Bravo Ortiz, Carmita María; Marziale, Maria Helena Palucci

    2010-01-01

    The aim of this descriptive study was to characterize the consumption of alcohol among workers in the administrative and service sectors at an Ecuadorian university and to determine differences in consumption between the two groups of workers. The Alcohol Use Disorders Identification Test (AUDIT) was applied to 102 participants. The results showed that the service personnel consumed more alcohol than the administrative personnel with a mean total score of 7.26 against 1.84. The total prevalence of non-prejudicial consumption was 79.41%, prejudicial consumption 19.61% and dependency 0.98%. The total scores of 76.47% of the participants were within risk zone one; 18.63% risk zone two; 3.92% risk zone three; 0.98% risk zone four. In conclusion, due to the identification of hazardous consumption, it is necessary to implement a program of alcohol use prevention in the institution studied. PMID:20694416

  19. Assessment of the Geothermal Potential Within the BPA Marketing Area.

    SciTech Connect

    Lund, John W.; Allen, Eliot D.

    1980-07-01

    The potential of geothermal energy is estimated that can be used for direct heat applications and electrical power generation within the Bonneville Power Administration (BPA) marketing area. The BPA marketing area includes three principal states of Oregon, Washington, and Idaho and portions of California, Montana, Wyoming, Nevada, and Utah bordering on these three states. This area covers approximately 384,000 square miles and has an estimated population of 6,760,000. The total electrical geothermal potential within this marketing area is 4077 MW/sub e/ from hydrothermal resources and 16,000 MW/sub e/ from igneous systems, whereas the total thermal (wellhead) potential is 16.15 x 10/sup 15/ Btu/y. Approximately 200 geothermal resource sites were initially identified within the BPA marketing area. This number was then reduced to about 100 sites thought to be the most promising for development by the year 2000. These 100 sites, due to load area overlap, were grouped into 53 composite sites; 21-3/4 within BPA preference customer areas and 31-1/4 within nonpreference customer areas. The geothermal resource potential was then estimated for high-temperature (> 302/sup 0/F = 150/sup 0/C), intermediate-temperature (194 to 302/sup 0/F = 90 to 150/sup 0/C), and low-temperature (< 194/sup 0/F = 90/sup 0/C) resources.

  20. 48 CFR 908.7101-2 - Consolidated acquisition of new vehicles by General Services Administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Services Administration. (a) New vehicles shall be procured in accordance with FPMR 41 CFR 101-25.304, 101-26.501, and 101-38.13, and DOE-PMR 41 CFR 109-25.304, 109-38.13, and 109-38.51. (b) Orders for all... accordance with FPMR 41 CFR 101-26.501. Requisitions for sedans, station wagons, and certain light trucks...

  1. 48 CFR 908.7101-2 - Consolidated acquisition of new vehicles by General Services Administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Services Administration. (a) New vehicles shall be procured in accordance with FPMR 41 CFR 101-25.304, 101-26.501, and 101-38.13, and DOE-PMR 41 CFR 109-25.304, 109-38.13, and 109-38.51. (b) Orders for all... accordance with FPMR 41 CFR 101-26.501. Requisitions for sedans, station wagons, and certain light trucks...

  2. Development and evaluation of a nursing service management and administration information system at district hospital.

    PubMed

    Stamouli, M A; Mantas, J

    2001-01-01

    The rapid development of information technology and the multiple usage of Information Systems make indisputable their appliance in all the sectors including the Nursing Service area. Information Systems that have been developed for the Nursing Service Administration are extremely useful in the processing and the categorisation of a large number of information, providing significant advantages such as information storage, information availability, information precision and reliability. In addition, the appliance of Information Systems provides important advantages in the administration of the nursing personnel's data, contributing to the improvement of the operating effectiveness of the Nursing Service. This paper describes the development and the evaluation of an Information System for the Nursing Service Administration that classifies all the information related to the nursing personnel and helps the administration to handle the appropriate nursing data. The method of Life Cycle Model was decided as the most appropriate for the development of the System, because of the important advantages that it offers. For the evaluation of our own designed system we based on the standards, which are used for evaluating Information Systems in general. The evaluation of this Information System is carried out by a survey among the undergraduate and the postgraduate students of the Nursing Department of the University of Athens and the Nursing Personnel of a number of Hospitals. Useful conclusions have been derived concerning those characteristics, which should be fulfilled by the system. Important conclusions have been also drown out concerning the dependencies of the variables under study, the future readjustments of the system, and the general perception of the newcomers in health profession towards the application of the information technology.

  3. Packaging effective community service delivery: the utility of mandates and contracts in obtaining administrative cooperation.

    PubMed

    Woodard, K L

    1994-01-01

    Voluntary agreements, mandates, and contracts integrate networks of social service organizations, allowing them to function as coordinated wholes. The author reviews the history of contracting and mandating in the public sector. It is hypothesized that contracted relationships formalize agreements between local organizations dependent on others. Mandated relationships are perceived to be important by policy-makers at a state or federal level. The differential acceptance and rejection of these relationships in the community is explored. Data from social service agencies are used to compare administrators' assessments of the effectiveness of mandated and contracted relationships used to coordinate a group of agencies delivering services to children. When a mandated relationship has been formalized into a contract by a local administrator the perceived effectiveness of that relationship is higher than any other relationship in the community. If the mandated relationship has not been formalized by a contract this relationship is perceived to be the least effective. Important mandated inter-organizational ties without monetary incentives are less likely to work. Local administrators having developed the contracted ties see these ties as producing a higher level of performance. PMID:10138341

  4. 76 FR 22708 - Centers for Disease Control and Prevention/Health Resources and Services Administration (CDC/HRSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... HUMAN SERVICES Centers for Disease Control and Prevention Centers for Disease Control and Prevention/Health Resources and Services Administration (CDC/HRSA) Advisory Committee on HIV and STD Prevention and... related to prevention and control of HIV/AIDS and other STDs, the support of health care services...

  5. Product-line administration: a framework for redefining medical record department services.

    PubMed

    Postal, S N

    1990-06-01

    Product-line administration is a viable approach for managing medical records services in an environment that demands high quantity and quality service levels. Product-line administration directs medical record department team members to look outside of the department and seek input from the customers it is intended to serve. The feedback received may be alarming at first, as the current state of products usually reveals a true lack of customer input. As the planning, defining, managing, and marketing phases are implemented, the road will not be easy and rewards will be slow to come. Product-line administration does not provide quick fixes, but it does provide long-term problem resolution as products are refined and new products developed to meet customer needs and expectations. In addition to better meeting the needs of the department's external customers, the department's internal customers' needs and expectations will be addressed. The participative management approach will help nurture each team member's creativity. The team members will have the opportunity to reach their full potential while reaping the rewards and benefits of providing products and services that meet the needs and expectations of all department customers. The future of the health care industry promises more changes as the country moves toward some form of prospective payment in the ambulatory setting. Reactive management and the constant struggle to catch up can no longer be accepted as a management approach. It is imperative that the medical record department be viewed as a business with product lines composed of quality products. The planning, defining, managing, and marketing components of product-line administration afford responsiveness to the current situation and the development of quality products that will ensure that medical record departments are prepared for the future.

  6. Evaluation of the Super Efficient Refrigerator Program (SERP) in the Bonneville Power Administration service territory

    SciTech Connect

    Lee, A.D.; Conger, R.L.

    1996-06-01

    The Super Efficient Refrigerator Program (SERP) is a collaborative utility program intended to transform the market for energy-efficient and environmentally friendly refrigerators. it is one of the first examples of large-scale {open_quotes}market transformation{close_quotes} energy efficiency program. This report documents the evaluation of SERP ({open_quotes}the Program{close_quotes}) in the Bonneville Power Administration`s (Bonneville`s) service territory. Pacific Northwest National Laboratory (PNNL) conducted this evaluation for Bonneville. This study includes the process evaluation, preliminary impact evaluation, and market transformation assessment. It is based on site visits and interviews with refrigerator dealers and manufacturers, industry data, and Bonneville information. Results from this study are compared with those from a parallel study that examines the Program across the 24 participating utilities.

  7. Molecular Mechanisms of Action of BPA.

    PubMed

    Acconcia, Filippo; Pallottini, Valentina; Marino, Maria

    2015-01-01

    Bisphenol A (BPA) exposure has been associated with serious endocrine-disrupting effects in humans and wildlife. Toxicological and epidemiological studies evidenced that BPA increases body mass index and disrupts normal cardiovascular physiology by interfering with endogenous hormones in rodents, nonhuman primates, and cell culture test systems. The BPA concentration derived from these experiments were used by government regulatory agencies to determine the safe exposure levels of BPA in humans. However, accumulating literature in vivo and in vitro indicate that at concentrations lower than that reported in toxicological studies, BPA could elicit a different endocrine-disrupting capacity. To further complicate this picture, BPA effects rely on several and diverse mechanisms that converge upon endocrine and reproductive systems. If all or just few of these mechanisms concur to the endocrine-disrupting potential of low doses of BPA is at present still unclear. Thus, taking into account that the incidence and/or prevalence of health problems associated with endocrine disruption have increased worldwide, the goal of the present review is to give an overview of the many mechanisms of BPA action in order to decipher whether different mechanisms are at the root of the effect of low dose of BPA on endocrine system. PMID:26740804

  8. Molecular Mechanisms of Action of BPA

    PubMed Central

    Acconcia, Filippo; Pallottini, Valentina

    2015-01-01

    Bisphenol A (BPA) exposure has been associated with serious endocrine-disrupting effects in humans and wildlife. Toxicological and epidemiological studies evidenced that BPA increases body mass index and disrupts normal cardiovascular physiology by interfering with endogenous hormones in rodents, nonhuman primates, and cell culture test systems. The BPA concentration derived from these experiments were used by government regulatory agencies to determine the safe exposure levels of BPA in humans. However, accumulating literature in vivo and in vitro indicate that at concentrations lower than that reported in toxicological studies, BPA could elicit a different endocrine-disrupting capacity. To further complicate this picture, BPA effects rely on several and diverse mechanisms that converge upon endocrine and reproductive systems. If all or just few of these mechanisms concur to the endocrine-disrupting potential of low doses of BPA is at present still unclear. Thus, taking into account that the incidence and/or prevalence of health problems associated with endocrine disruption have increased worldwide, the goal of the present review is to give an overview of the many mechanisms of BPA action in order to decipher whether different mechanisms are at the root of the effect of low dose of BPA on endocrine system. PMID:26740804

  9. Molecular Mechanisms of Action of BPA.

    PubMed

    Acconcia, Filippo; Pallottini, Valentina; Marino, Maria

    2015-01-01

    Bisphenol A (BPA) exposure has been associated with serious endocrine-disrupting effects in humans and wildlife. Toxicological and epidemiological studies evidenced that BPA increases body mass index and disrupts normal cardiovascular physiology by interfering with endogenous hormones in rodents, nonhuman primates, and cell culture test systems. The BPA concentration derived from these experiments were used by government regulatory agencies to determine the safe exposure levels of BPA in humans. However, accumulating literature in vivo and in vitro indicate that at concentrations lower than that reported in toxicological studies, BPA could elicit a different endocrine-disrupting capacity. To further complicate this picture, BPA effects rely on several and diverse mechanisms that converge upon endocrine and reproductive systems. If all or just few of these mechanisms concur to the endocrine-disrupting potential of low doses of BPA is at present still unclear. Thus, taking into account that the incidence and/or prevalence of health problems associated with endocrine disruption have increased worldwide, the goal of the present review is to give an overview of the many mechanisms of BPA action in order to decipher whether different mechanisms are at the root of the effect of low dose of BPA on endocrine system.

  10. Increasing Access to Health Administrative Data with ICES Data & Analytic Services.

    PubMed

    Ishiguro, Lisa; Saskin, Refik; Vermeulen, Marian J; Yates, Erika; Gunraj, Nadia; Victor, J Charles

    2016-01-01

    The Institute for Clinical Evaluative Sciences (ICES) is one of only a few organizations in Ontario permitted to access, link and analyze health administrative data for the purpose of generating evidence to inform decisions in policy and practice. Although ICES is a leading research institute, its access to the data has historically been restricted to scientists with an ICES affiliation. This requirement, designed to meet ICES' data privacy and security obligations, created barriers with respect to the widespread use of Ontario's data assets. In 2014, as part of the government's commitment to the Strategy for Patient-Oriented Research, ICES launched the Data & Analytic Services platform, which is aimed at increasing access to data and analytic services to investigators external to ICES. In making the data widely available to the broader research community, this initiative engages investigators involved in front-line care, stimulates new avenues of research and fosters collaboration that was previously challenging or unfeasible. PMID:27133600

  11. The Joy of Social Work Administration: An Exploratory Qualitative Study of Human Service Administrators' Positive Perceptions of Their Work

    ERIC Educational Resources Information Center

    Watson, Larry D.; Hoefer, Richard A.

    2016-01-01

    Positive organizational psychology suggests that researchers should focus on the rewarding elements of work life, yet those in the fields of social work and nonprofit administration have not conducted research in line with this admonition. Indeed, the current focus on administrative challenges and problems may be part of the reason there is…

  12. Public service quality improvements: a case for exemption from IRB review of public administration research.

    PubMed

    Jordan, Sara R

    2014-01-01

    Should the exemption from Institutional Review Board (IRB) evaluations currently in place for quality improvements research be extended to public administration research that addresses questions of improving the quality of public service delivery? As a means to both reduce the level of disdain held by a group of social science researchers for IRBs and to reduce the cost of review for minimal risk studies, I argue here that much of the current public administration research should also be exempted from normal processes of review by IRBs on the basis of their similarity to Quality Improvements (QI) research, a category of studies already granted exemption. This argument dovetails provisions currently in place for studies of public service and public benefit, but reframes these exemptions in the language of "quality improvements," which may be a more comfortable language for IRBs concerned to demonstrate compliance for review of all fields. To expedite this argument into the practices of IRBs, I included a checklist that researchers could use to self-identify their studies as QI, not research as such. PMID:24228974

  13. Factors Affecting Student Affairs Administrators' Views of Campus Services for International Students at Five Public Universities in Ohio

    ERIC Educational Resources Information Center

    Di Maria, David L.

    2012-01-01

    The purpose of this study was to determine factors affecting views of campus services for international students among student affairs administrators. Factors identified during the literature review were examined using a multiple perspectives framework, which combined concepts related to student affairs administration, strategic planning for…

  14. 47 CFR 54.725 - Universal service disbursements during pendency of a request for review and Administrator decision.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Administrator decision under § 54.719(a) through (c) in connection with the high cost and low income support... § 54.719(a) through (c) in connection with the schools and libraries support mechanism or the rural health care support mechanism, the Administrator shall not reimburse a service provider for the...

  15. 41 CFR 105-68.630 - May the General Services Administration impute conduct of one person to another?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Administration impute conduct of one person to another? 105-68.630 Section 105-68.630 Public Contracts and... Services Administration impute conduct of one person to another? For purposes of actions taken under this... to another individual, if the individual to whom the improper conduct is imputed either...

  16. Measuring Pre-Service Master's of School Administrator's Candidates' Social Capital as a Predictor of Culturally Responsive Leadership

    ERIC Educational Resources Information Center

    Taliaferro, Alisa; Seigler, Timothy

    2012-01-01

    This study measured Pre-Service Masters of School Administrators' candidates' social capital as a predictor of culturally responsive leadership. The purpose of this research was to examine the relationship between the MSA Pre-service candidates' social capital and their propensity to become culturally responsive leaders. The 23 participants in…

  17. 41 CFR 105-54.309 - Added responsibilities of service and staff office heads and regional administrators.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Added responsibilities of service and staff office heads and regional administrators. 105-54.309 Section 105-54.309 Public... 54.3-Advisory Committee Procedures § 105-54.309 Added responsibilities of service and staff...

  18. 41 CFR 105-54.309 - Added responsibilities of service and staff office heads and regional administrators.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Added responsibilities of service and staff office heads and regional administrators. 105-54.309 Section 105-54.309 Public... 54.3-Advisory Committee Procedures § 105-54.309 Added responsibilities of service and staff...

  19. 75 FR 78997 - Centers for Disease Control and Prevention/Health Resources and Services Administration (CDC/HRSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... HUMAN SERVICES Centers for Disease Control and Prevention Centers for Disease Control and Prevention/Health Resources and Services Administration (CDC/HRSA) Advisory Committee on HIV and STD Prevention and...-463) of October 6, 1972, that the CDC/HRSA Advisory Committee on HIV and STD Prevention and...

  20. Barriers and Facilitators to Adoption of Genomic Services for Colorectal Care within the Veterans Health Administration

    PubMed Central

    Sperber, Nina R.; Andrews, Sara M.; Voils, Corrine I.; Green, Gregory L.; Provenzale, Dawn; Knight, Sara

    2016-01-01

    We examined facilitators and barriers to adoption of genomic services for colorectal care, one of the first genomic medicine applications, within the Veterans Health Administration to shed light on areas for practice change. We conducted semi-structured interviews with 58 clinicians to understand use of the following genomic services for colorectal care: family health history documentation, molecular and genetic testing, and genetic counseling. Data collection and analysis were informed by two conceptual frameworks, the Greenhalgh Diffusion of Innovation and Andersen Behavioral Model, to allow for concurrent examination of both access and innovation factors. Specialists were more likely than primary care clinicians to obtain family history to investigate hereditary colorectal cancer (CRC), but with limited detail; clinicians suggested templates to facilitate retrieval and documentation of family history according to guidelines. Clinicians identified advantage of molecular tumor analysis prior to genetic testing, but tumor testing was infrequently used due to perceived low disease burden. Support from genetic counselors was regarded as facilitative for considering hereditary basis of CRC diagnosis, but there was variability in awareness of and access to this expertise. Our data suggest the need for tools and policies to establish and disseminate well-defined processes for accessing services and adhering to guidelines. PMID:27136589

  1. Barriers and Facilitators to Adoption of Genomic Services for Colorectal Care within the Veterans Health Administration.

    PubMed

    Sperber, Nina R; Andrews, Sara M; Voils, Corrine I; Green, Gregory L; Provenzale, Dawn; Knight, Sara

    2016-01-01

    We examined facilitators and barriers to adoption of genomic services for colorectal care, one of the first genomic medicine applications, within the Veterans Health Administration to shed light on areas for practice change. We conducted semi-structured interviews with 58 clinicians to understand use of the following genomic services for colorectal care: family health history documentation, molecular and genetic testing, and genetic counseling. Data collection and analysis were informed by two conceptual frameworks, the Greenhalgh Diffusion of Innovation and Andersen Behavioral Model, to allow for concurrent examination of both access and innovation factors. Specialists were more likely than primary care clinicians to obtain family history to investigate hereditary colorectal cancer (CRC), but with limited detail; clinicians suggested templates to facilitate retrieval and documentation of family history according to guidelines. Clinicians identified advantage of molecular tumor analysis prior to genetic testing, but tumor testing was infrequently used due to perceived low disease burden. Support from genetic counselors was regarded as facilitative for considering hereditary basis of CRC diagnosis, but there was variability in awareness of and access to this expertise. Our data suggest the need for tools and policies to establish and disseminate well-defined processes for accessing services and adhering to guidelines. PMID:27136589

  2. Barriers and Facilitators to Adoption of Genomic Services for Colorectal Care within the Veterans Health Administration.

    PubMed

    Sperber, Nina R; Andrews, Sara M; Voils, Corrine I; Green, Gregory L; Provenzale, Dawn; Knight, Sara

    2016-04-28

    We examined facilitators and barriers to adoption of genomic services for colorectal care, one of the first genomic medicine applications, within the Veterans Health Administration to shed light on areas for practice change. We conducted semi-structured interviews with 58 clinicians to understand use of the following genomic services for colorectal care: family health history documentation, molecular and genetic testing, and genetic counseling. Data collection and analysis were informed by two conceptual frameworks, the Greenhalgh Diffusion of Innovation and Andersen Behavioral Model, to allow for concurrent examination of both access and innovation factors. Specialists were more likely than primary care clinicians to obtain family history to investigate hereditary colorectal cancer (CRC), but with limited detail; clinicians suggested templates to facilitate retrieval and documentation of family history according to guidelines. Clinicians identified advantage of molecular tumor analysis prior to genetic testing, but tumor testing was infrequently used due to perceived low disease burden. Support from genetic counselors was regarded as facilitative for considering hereditary basis of CRC diagnosis, but there was variability in awareness of and access to this expertise. Our data suggest the need for tools and policies to establish and disseminate well-defined processes for accessing services and adhering to guidelines.

  3. Health service utilization in IBD: comparison of self-report and administrative data

    PubMed Central

    2011-01-01

    Background The reliability of self-report regarding health care utilization in inflammatory bowel disease (IBD) is unknown. If proven reliable, it could help justify self-report as a means of determining health care utilization and associated costs. Methods The Manitoba IBD Cohort Study is a population-based longitudinal study of participants diagnosed within 7 years of enrollment. Health care utilization was assessed through standardized interview. Participants (n = 352) reported the total number of nights hospitalized, frequency of physician contacts in the prior 12 months and whether the medical contacts were for IBD-related reasons or not. Reports of recent antibiotic use were also recorded. Actual utilization was drawn from the administrative database of Manitoba Health, the single comprehensive provincial health insurer. Results According to the administrative data, 15% of respondents had an overnight hospitalization, while 10% had an IBD-related hospitalization. Self-report concordance was highly sensitive (92%; 82%) and specific (96%; 97%, respectively). 97% of participants had contact with a physician in the previous year, and 69% had IBD-related visits. Physician visits were significantly under-reported and there was a trend to over-report the number of nights in hospital. Conclusions Self-report data can be helpful in evaluating health service utilization, provided that the researcher is aware of the systematic sources of bias. Outpatient visits are well identified by self-report. The discordance for the type of outpatient visit may be either a weakness of self-report or a flaw in diagnosis coding of the administrative data. If administrative data are not available, self-report information may be a cost-effective alternative, particularly for hospitalizations. PMID:21627808

  4. Descriptive study of stress and satisfaction at work in the Saragossa university services and administration staff

    PubMed Central

    2010-01-01

    Background The notion of stress in connection with the work environment became an important topic during the 1970's, when the first studies on the subject were published and the term of work stress was first coined. In 1974, Freudenberger proposed the term burnout to refer to the condition of physical and emotional exhaustion, as well as the associated negative attitudes, resulting from the intense interaction in working with people. The aim of our study is to examine burnout and job satisfaction in Saragossa University Services and Administration Staff (SAS) and detect the main factors which could contribute to too much stress, because job stress has emerged as a major psychosocial influence on mental health, associated with burnout. Methods 24 people from the Services and Administration Staff in the University of Saragossa participated in the study. The research was carried out during the implementation of a module on Stress Management organised by the University of Saragossa and commissioned to the Unit for Research in Physical Therapy (University School of Health Sciences) from that University. This research is an exploratory research to improve the stress management program. A personal interview was carried out and additionally, participants were given the Maslach Burnout Inventory and the Scale of Satisfaction at Work of Warr, Cook & Wall. Results However using small sample this is worth to state that participants present most of them low burnout levels in the burnout scale. Only in one person high exhaustion level was reflected, even though other seven showed mean levels; in the professional self-esteem section, most of them showed high self-esteem, with two cases of low self-esteem and five with mean level. With regard to satisfaction people participating in the study show mean levels in intrinsic as much as in extrinsic factors and general satisfaction. Conclusions Services and Administration Staff from the University of Saragossa shows low burnout levels

  5. Renewable Energy Demonstration Project by the National Renewable Energy Laboratory and the General Services Administration

    NASA Astrophysics Data System (ADS)

    Carlisle, Nancy; Hoo, Ed; Westby, Robert; Hancock, Ed; Lu, J.

    1994-11-01

    The Energy Policy Act of 1992 (EPACT) requires the General Services Administration (GSA) to implement a solar energy program to demonstrate and evaluate the performance of available technologies expected to have widespread commercial application. The GSA decided to carry out the project at the Denver Federal Center because of its proximity to the National Renewable Energy Laboratory (NREL). The location was thought to be of mutual benefit to NREL and the GSA: it provides NREL an opportunity to deploy technology and it provides the GSA an opportunity to gain a hands-on learning experience with renewables. The GSA plans to document their experience and use it as a case study in part of a larger training effort on renewable energy. This paper describes the technology selection process and provides an update on the status of the project.

  6. Dental School Administrators' Attitudes Towards Providing Support Services for LGBT-Identified Students.

    PubMed

    Behar-Horenstein, Linda S; Morris, Dustin R

    2015-08-01

    A lack of curriculum time devoted to teaching dental students about the needs of lesbian, gay, bisexual, and transgendered (LGBT) health care patient needs and biases against LGBT students and faculty have been reported. Understanding dental school administrators' attitudes about LGBT students' needs might provide further insight into these long-standing issues. The aims of this study were to develop a survey to assess dental administrators' attitudes regarding the support services they believe LGBT-identified students need, to identify dental schools' current diversity inclusion policies, and to determine what types of support dental schools currently provide to LGBT students. A survey developed with the aid of a focus group, cognitive interviewing, and pilot testing was sent to 136 assistant and associate deans and deans of the 65 U.S. and Canadian dental schools. A total of 54 responses from 43 (66%) schools were received from 13 deans, 29 associate deans, and 11 assistant deans (one participant did not report a position), for a 40% response rate. The findings suggest there is a considerable lack of knowledge or acknowledgment of LGBT dental students' needs. Future studies are needed to show the importance of creating awareness about meeting the needs of all dental student groups, perhaps through awareness campaigns initiated by LGBT students.

  7. Dental School Administrators' Attitudes Towards Providing Support Services for LGBT-Identified Students.

    PubMed

    Behar-Horenstein, Linda S; Morris, Dustin R

    2015-08-01

    A lack of curriculum time devoted to teaching dental students about the needs of lesbian, gay, bisexual, and transgendered (LGBT) health care patient needs and biases against LGBT students and faculty have been reported. Understanding dental school administrators' attitudes about LGBT students' needs might provide further insight into these long-standing issues. The aims of this study were to develop a survey to assess dental administrators' attitudes regarding the support services they believe LGBT-identified students need, to identify dental schools' current diversity inclusion policies, and to determine what types of support dental schools currently provide to LGBT students. A survey developed with the aid of a focus group, cognitive interviewing, and pilot testing was sent to 136 assistant and associate deans and deans of the 65 U.S. and Canadian dental schools. A total of 54 responses from 43 (66%) schools were received from 13 deans, 29 associate deans, and 11 assistant deans (one participant did not report a position), for a 40% response rate. The findings suggest there is a considerable lack of knowledge or acknowledgment of LGBT dental students' needs. Future studies are needed to show the importance of creating awareness about meeting the needs of all dental student groups, perhaps through awareness campaigns initiated by LGBT students. PMID:26246536

  8. Identification of American Indian and Alaska Native veterans in administrative data of the Veterans Health Administration and the Indian Health Service.

    PubMed

    Kramer, B Josea; Wang, Mingming; Hoang, Tuyen; Harker, Judith O; Finke, Bruce; Saliba, Debra

    2006-09-01

    We sought to determine the extent to which the Indian Health Service (IHS) identified enrollees who also use the Veterans Health Administration (VHA) as veterans. We used a bivariate analysis of administrative data from fiscal years 2002-2003 to study the target population. Of the 32259 IHS enrollees who received care as veterans in the VHA, only 44% were identified by IHS as veterans. IHS data underestimates the number of veterans, and both IHS and VHA need mechanisms to recognize mutual beneficiaries in order to facilitate better coordination of strategic planning and resource sharing among federal health care agencies. PMID:16873744

  9. Medicaid: Determining Cost-Effectiveness of Home and Community-Based Services. Report to the Administrator, Health Care Financing Administration, Department of Health and Human Services.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC.

    To examine alternatives to nursing home care, states have been testing home and community-based services under the Medicaid program. Information on the operations of the state projects will be vital to designing cost-effective alternative services in the future. The General Accounting Office (GAO) reviewed state reports to see if accurate,…

  10. The Audio-Visual Services in Fifteen African Countries. Comparative Study on the Administration of Audio-Visual Services in Advanced and Developing Countries. Part Four. First Edition.

    ERIC Educational Resources Information Center

    Jongbloed, Harry J. L.

    As the fourth part of a comparative study on the administration of audiovisual services in advanced and developing countries, this UNESCO-funded study reports on the African countries of Cameroun, Republic of Central Africa, Dahomey, Gabon, Ghana, Kenya, Libya, Mali, Nigeria, Rwanda, Senegal, Swaziland, Tunisia, Upper Volta and Zambia. Information…

  11. Review of BPA Funded Sturgeon, Resident Fish and Wildlife Projects, 1989/1990.

    SciTech Connect

    United States. Bonneville Power Administration.

    1990-12-01

    The Bonneville Power Administration (BPA) held a public meeting on November 6-7, 1990, for the purpose of review, coordination, and consultation of the BPA-funded projects for sturgeon, resident fish, and wildlife in the Columbia River Basin (Basin). The comments received after the meeting were favorable and the participants agreed that the meeting was stimulating and productive. The information exchanged should lead to better coordination with other projects throughout the Basin. The following pages list the projects by title, the project leaders and BPA's project officers, and an abstract of each leaders presentation. These summaries are in some cases preliminary; they are subject to change and should not be quoted without consulting the project leader.

  12. Landowner’s Guide for Compatible Use of BPA Rights-of-Way

    SciTech Connect

    2011-02-01

    Keeping transmission lines safe and reliable is a critical priority for the Bonneville Power Administration. The key element in achieving those objectives is BPA’s ability to construct, operate and maintain its transmission lines and rights-of-way — the area under and around the lines. You can help BPA keep these rights-of-way clear of trees, brush and structures that could affect the safety or reliability of the transmission system. Prior to planting, digging, or constructing within BPA’s rights-of-way, fill out BPA’s Land Use Application Form. The information you provide on the application helps BPA understand your proposed use and the potential impacts to public safety, and the safety of our crews. BPA also reviews the application to determine whether a proposed use of land is compatible with the construction, operation and maintenance of BPA transmission lines. Coordinating with BPA early in your planning process can keep you safe and avoid wasting time and money.

  13. National Nuclear Security Administration Service Center Environmental Programs Long-Term Environmental Stewardship Baseline Handbook

    SciTech Connect

    Griswold, D. D.; Rohde, K.

    2003-02-26

    As environmental restoration (ER) projects move toward completion, the planning, integration, and documentation of long-term environmental stewardship (LTES) activities is increasingly important for ensuring smooth transition to LTES. The Long-Term Environmental Stewardship Baseline Handbook (Handbook) prepared by the National Nuclear Security Administration (NNSA) Service Center Environmental Programs Department (EPD) outlines approaches for integrating site-specific LTES planning and implementation into site ER baseline documentation. Since LTES will vary greatly from site to site, the Handbook also provides for flexibility in addressing LTES in ER Project life-cycle baselines, while clearly identifying Environmental Management (EM) requirements. It provides suggestions for enacting LTES principles and objectives through operational activities described in site-specific LTES plans and life cycle ER Project baseline scope, cost, and schedule documentation and tools for more thorough planning, better quantification, broader understanding of risk and risk management factors, and more comprehensive documentation. LTES planning applied to baselines in a phased approach will facilitate seamlessly integrating LTES into site operational activities, thereby minimizing the use of resources.

  14. 42 CFR 484.14 - Condition of participation: Organization, services, and administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... therapeutic service (physical, speech, or occupational therapy; medical social services; or home health aide...'s ongoing functions; maintains ongoing liaison among the governing body, the group of...

  15. 42 CFR 418.100 - Condition of Participation: Organization and administration of services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... counseling. (v) Hospice aide, volunteer, and homemaker services. (vi) Physical therapy, occupational therapy, and speech-language pathology services. (vii) Short-term inpatient care. (viii) Medical...

  16. BPA Riparian Fencing and Alternative Water Development Projects Completed within Asotin Creek Watershed, 2000 and 2001 Asotin Creek Fencing Final Report of Accomplishments.

    SciTech Connect

    Johnson, B.J.

    2002-01-01

    The Asotin County Conservation District (ACCD) is the primary entity coordinating habitat projects on both private and public lands within the Asotin Creek watershed. The watershed covers approximately 325 square miles in the Blue Mountains of southeastern Washington in Water Resource Inventory Area (WRIA) 35. According to Washington Department of Fish and Wildlife's (WDFW) Priority WRIA's by ''At-Risk Stock Significance Map'', it is the highest priority WRIA in southeastern Washington. Summer steelhead, bull trout, and Snake River spring chinook salmon which are listed under the Endangered Species Act (ESA), are present in the watershed. WDFW manages it as a Wild Steelhead Reserve; no hatchery fish have been released here since 1997. The ACCD has been working with landowners, Bonneville Power Administration (BPA), Washington State Conservation Commission (WCC), Natural Resource Conservation Service (NRCS), Washington Department of Fish and Wildlife (WDFW), U.S. Forest Service, Pomeroy Ranger District (USFS), Nez Perce Tribe, Washington Department of Ecology (DOE), National Marine Fisheries Service (NMFS), and U.S. Fish and Wildlife Service (USFWS) to address habitat projects in Asotin County. Local students, volunteers and Salmon Corps members from the Nez Perce Tribe have been instrumental in the success of the Model Watershed Program on Asotin Creek. ACCD began coordinating habitat projects in 1995 with the help of BPA funding. Approximately two hundred and seventy-six projects have been implemented as of 1999. The Washington State Legislature was successful in securing funding for endangered salmon and steelhead recovery throughout the State in 1998. While these issues were new to most of the State, the ACCD has been securing and administering funding for endangered salmonids since 1994. The ''Asotin Creek Riparian Planting 2000-053-00 and Asotin Creek Riparian Fencing 2000-054-00'' teamed BPA and the Governor's Salmon Recovery Funding to plant approximately 84

  17. 38 CFR 3.360 - Service-connected health-care eligibility of certain persons administratively discharged under...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Service-connected health-care eligibility of certain persons administratively discharged under other than honorable condition. (a) General. The health-care and related benefits authorized by chapter 17 of title 38... bars listed in § 3.12(c) applies. (c) Eligibility criteria. In making determinations of...

  18. 38 CFR 3.360 - Service-connected health-care eligibility of certain persons administratively discharged under...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Service-connected health-care eligibility of certain persons administratively discharged under other than honorable condition. (a) General. The health-care and related benefits authorized by chapter 17 of title 38... bars listed in § 3.12(c) applies. (c) Eligibility criteria. In making determinations of...

  19. 38 CFR 3.360 - Service-connected health-care eligibility of certain persons administratively discharged under...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Service-connected health-care eligibility of certain persons administratively discharged under other than honorable condition. (a) General. The health-care and related benefits authorized by chapter 17 of title 38... bars listed in § 3.12(c) applies. (c) Eligibility criteria. In making determinations of...

  20. 38 CFR 3.360 - Service-connected health-care eligibility of certain persons administratively discharged under...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Service-connected health-care eligibility of certain persons administratively discharged under other than honorable condition. (a) General. The health-care and related benefits authorized by chapter 17 of title 38... bars listed in § 3.12(c) applies. (c) Eligibility criteria. In making determinations of...

  1. 38 CFR 3.360 - Service-connected health-care eligibility of certain persons administratively discharged under...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Service-connected health-care eligibility of certain persons administratively discharged under other than honorable condition. (a) General. The health-care and related benefits authorized by chapter 17 of title 38... bars listed in § 3.12(c) applies. (c) Eligibility criteria. In making determinations of...

  2. 41 CFR 102-38.330 - Are there any reports that we must submit to the General Services Administration?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... days after the close of each fiscal year, you must provide GSA with a listing and description of all... sale. (b) Exchange/sale report. Within 90 calendar days after the close of each fiscal year, you must... that we must submit to the General Services Administration? 102-38.330 Section 102-38.330...

  3. 41 CFR 102-71.5 - What is the scope and philosophy of the General Services Administration's (GSA) real property...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What is the scope and philosophy of the General Services Administration's (GSA) real property policies? 102-71.5 Section 102-71.5...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 71-GENERAL § 102-71.5 What is the scope and philosophy of...

  4. 41 CFR 102-71.5 - What is the scope and philosophy of the General Services Administration's (GSA) real property...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What is the scope and philosophy of the General Services Administration's (GSA) real property policies? 102-71.5 Section 102-71.5...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 71-GENERAL § 102-71.5 What is the scope and philosophy of...

  5. 41 CFR 102-71.5 - What is the scope and philosophy of the General Services Administration's (GSA) real property...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What is the scope and philosophy of the General Services Administration's (GSA) real property policies? 102-71.5 Section 102-71.5...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 71-GENERAL § 102-71.5 What is the scope and philosophy of...

  6. 75 FR 22145 - Health Resources and Services Administration (HRSA); CDC/HRSA Advisory Committee on HIV and STD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ... (HRSA); CDC/HRSA Advisory Committee on HIV and STD Prevention and Treatment (CHACHSPT) In accordance... the Administrator, HRSA, regarding activities related to the prevention and control of HIV/AIDS and other STDs, the support of healthcare services to persons living with HIV/AIDS, and the education...

  7. A Demonstration Project for Administrative Trainees in Social Service Agencies September 1, 1967 - August 31, 1968. Final Report.

    ERIC Educational Resources Information Center

    1968

    Sponsored by Camp Fire Girls, Inc. and Girl Scouts of the U.S.A., under contract with the United States Department of Labor, this demonstration project was designed to explore the practicability of a program of non-credit college study and work experience to prepare women for administrative positions with social service agencies. Programs were set…

  8. 41 CFR 102-71.5 - What is the scope and philosophy of the General Services Administration's (GSA) real property...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What is the scope and philosophy of the General Services Administration's (GSA) real property policies? 102-71.5 Section 102-71.5...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 71-GENERAL § 102-71.5 What is the scope and philosophy of...

  9. 41 CFR 102-71.5 - What is the scope and philosophy of the General Services Administration's (GSA) real property...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is the scope and philosophy of the General Services Administration's (GSA) real property policies? 102-71.5 Section 102-71.5...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 71-GENERAL § 102-71.5 What is the scope and philosophy of...

  10. A Review of the Major Issues and Problems of Welfare Reform; A Background Paper Developed for the Community Services Administration.

    ERIC Educational Resources Information Center

    Technical Assistance Research Programs, Inc., Washington, DC.

    This background paper was developed for the Community Services Administration (CSA) in order to provide background information concerning welfare reform. It examines possible public assistance strategies, such as the following: (1) broad-based cash transfer (negative income tax, wage rate subsidies, demogrants, and family allowances), (2)…

  11. Social Work Values in Human Services Administration: Implications for Social Work Education

    ERIC Educational Resources Information Center

    Watson, Larry D.; Hoefer, Richard

    2014-01-01

    The perceived wisdom in the social work education community, based on empirical research from the 1990s and the early part of this century, says that the master of social work (MSW) degree is not competitive with the master of business administration or the master of public administration to obtain top-level administration jobs in nonprofit…

  12. Bonneville Power Administration 1991 site environmental report

    SciTech Connect

    Not Available

    1992-06-01

    In 1991, in order to provide BPA's management with environmental information for decision making, and to comply with the National Environmental Policy Act (NEPA) of 1969, BPA completed 15 environmental impact evaluations and decision documents, with many more in progress. BPA received the results of two US Department of Energy (DOE) environmental management audits, which noted areas for improvement in our operations. We completed Action Plans in response to each DOE report. We received one administrative complaint from the US Environmental Protection Agency (EPA) concerning a 1990 spill in Arlington, Oregon, caused by a BPA subcontractor. BPA responded promptly to EPA's findings and concerns. There were 32 new spill/release incidents, most involving failure of Polychlorinated biphenyl (PCB) capacitors. Cleanup of these spills/releases has proceeded satisfactorily. BPA continued vigorous efforts to clean up substations contaminated with residuals of oil and PCB from past spills. BPA took several actions to improve our environmental performance with respect to water quality. The BPA environmental team developed a long-term schedule for environmental appraisals and audits, identifying facilities and projects that will receive audits through 1996.

  13. Bonneville Power Administration Site Environmental Report, 1991.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-06-01

    In 1991, in order to provide BPA`s management with environmental information for decision making, and to comply with the National Environmental Policy Act (NEPA) of 1969, BPA completed 15 environmental impact evaluations and decision documents, with many more in progress. BPA received the results of two US Department of Energy (DOE) environmental management audits, which noted areas for improvement in our operations. We completed Action Plans in response to each DOE report. We received one administrative complaint from the US Environmental Protection Agency (EPA) concerning a 1990 spill in Arlington, Oregon, caused by a BPA subcontractor. BPA responded promptly to EPA`s findings and concerns. There were 32 new spill/release incidents, most involving failure of Polychlorinated biphenyl (PCB) capacitors. Cleanup of these spills/releases has proceeded satisfactorily. BPA continued vigorous efforts to clean up substations contaminated with residuals of oil and PCB from past spills. BPA took several actions to improve our environmental performance with respect to water quality. The BPA environmental team developed a long-term schedule for environmental appraisals and audits, identifying facilities and projects that will receive audits through 1996.

  14. 78 FR 14303 - Statement of Delegation of Authority; Health Resources and Services Administration and Centers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ... Services under Title III, Part R, Section 399BB, titled ``Autism, Education, Early Detection, and Intervention,'' of the Public Health Service (PHS) Act, as amended, insofar as such authority pertains to...

  15. Bonneville Purchasing Instructions. Appendix 14A, Contracting Officer`s Technical Representatives` Guide for Services Contracts.

    SciTech Connect

    United States. Bonneville Power Administration.

    1993-07-01

    This guide outlines the duties of BPA personnel designated as Contracting Officers Technical Representatives (COTRs). The BPA Administrator gives contracting officers (COs) in BPA responsibility and authority for awarding and administering contracts. COs are authorized to designate other BPA employees to act as their representatives for purposes of contract administration, from the time of contract award until final receipt and acceptance of the contracted services. COTRs are the individuals primarily relied upon to perform technical contract administration functions. Similar functions for supply and construction contracts are performed by engineering representatives, construction inspectors, and inspectors. Although this Guide is written primarily with the COTR in mind, the concept and operation of teamwork is essential throughout the entire process of contract administration. The CO administers the contract during performance, but rarely has expertise in all of the relevant technical areas. Therefore, CO decisions rely on input from a team. The COTR is an indispensable member of that team. The instructions in this Guide are designed to facilitate this essential CO-COTR cooperation. COTR duties are usually additional to those required of the COTR in his or her assigned line organization. The COTR is still accountable to the line supervisor for performance of regularly-assigned duties. These duties are to be reflected appropriately in performance appraisals and job descriptions. For contract administration duties, however, the COTR reports directly to, and is accountable only to, the CO. The COTR`s supervisor must allow sufficient time to ensure that the COTR can adequately monitor the contract for technical compliance. This Guide is designed for COTRs who are performing service contract (including intergovernmental contract) administration functions as an adjunct to their normal technical duties.

  16. 75 FR 13129 - General Services Administration Acquisition Regulation; Submission for OMB Review; Sales Practice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... Format--Supplies and/or Services With an Established Catalog Price and Sales Practices Format-- Supplies and/or Services With Market Pricing Without an Established Catalog Price AGENCY: Office of the Chief... an Established Catalog Price and Sales Practices Format--Supplies and/or Services with Market...

  17. Service Learning in a Master of Business Administration (MBA) Integrative Project Course: An Experience in China

    ERIC Educational Resources Information Center

    Coffey, Betty S.; Wang, Jia

    2006-01-01

    Service learning is a teaching method used by business faculty to link the learning goals and objectives of an academic course with meaningful community service. Although service learning has been advanced in business education in the United States and other Western countries, little has been reported on its use outside the Western context. In…

  18. Disparity in Naloxone Administration by Emergency Medical Service Providers and the Burden of Drug Overdose in US Rural Communities

    PubMed Central

    Dailey, Michael W.; Sugerman, David E.; Sasser, Scott M.; Levy, Benjamin; Paulozzi, Len J.

    2015-01-01

    Objectives. We determined the factors that affect naloxone (Narcan) administration in drug overdoses, including the certification level of emergency medical technicians (EMTs). Methods. In 2012, 42 states contributed all or a portion of their ambulatory data to the National Emergency Medical Services Information System. We used a logistic regression model to measure the association between naloxone administration and emergency medical services certification level, age, gender, geographic location, and patient primary symptom. Results. The odds of naloxone administration were much higher among EMT-intermediates than among EMT-basics (adjusted odds ratio [AOR] = 5.4; 95% confidence interval [CI] = 4.5, 6.5). Naloxone use was higher in suburban areas than in urban areas (AOR = 1.41; 95% CI = 1.3, 1.5), followed by rural areas (AOR = 1.23; 95% CI = 1.1, 1.3). Although the odds of naloxone administration were 23% higher in rural areas than in urban areas, the opioid drug overdose rate is 45% higher in rural communities. Conclusions. Naloxone is less often administered by EMT-basics, who are more common in rural areas. In most states, the scope-of-practice model prohibits naloxone administration by basic EMTs. Reducing this barrier could help prevent drug overdose death. PMID:25905856

  19. Burnout and Job Satisfaction in Rehabilitation Administrators and Direct Service Providers.

    ERIC Educational Resources Information Center

    Riggar, T. F.; And Others

    1984-01-01

    Compared levels of burnout and job satisfaction in 124 rehabilitation counselors and 115 administrators, using the Maslach Burnout Inventory and the Muthard and Miller Job Satisfaction Inventory. Results showed administrators reported higher levels of job satisfaction than counselors and that an inverse relationship existed between job…

  20. Faculty Perspectives on Academic Work and Administrative Burden: Implications for the Design of Effective Support Services

    ERIC Educational Resources Information Center

    Wimsatt, Leslie; Trice, Andrea; Langley, David

    2009-01-01

    This paper uses literature on faculty worklife and findings from a recent study conducted by the Federal Demonstration Partnership (FDP) to shed light on the sources and extent of administrative burden experienced by faculty engaged in federal grant research. Discussion focuses on the implications for research administrators, including strategies…

  1. 75 FR 39045 - Hewlett-Packard Company Division of Corporate Administration and Shared Services Including On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... Employment and Training Administration Hewlett-Packard Company Division of Corporate Administration and... Various States in the United States Reporting to Omaha, NE; Including Employees of Hewlett-Packard Company... to Apply for Worker Adjustment Assistance on May 20, 2010, applicable to workers of...

  2. Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation

    PubMed Central

    McCaffrey, Katherine A.; Jones, Brian; Mabrey, Natalie; Weiss, Bernard; Swan, Shanna H.; Patisaul, Heather B.

    2013-01-01

    Bisphenol A (BPA) is a high volume production chemical used in polycarbonate plastics, epoxy resins, thermal paper receipts, and other household products. The neural effects of early life BPA exposure, particularly to low doses administered orally, remain unclear. Thus, to better characterize the dose range over which BPA alters sex specific neuroanatomy, we examined the impact of perinatal BPA exposure on two sexually dimorphic regions in the anterior hypothalamus, the sexually dimorphic nucleus of the preoptic area (SDN-POA) and the anterioventral periventricular (AVPV) nucleus. Both are sexually differentiated by estradiol and play a role in sex specific reproductive physiology and behavior. Long Evans rats were prenatally exposed to 10, 100, 1000, 10,000 mg/kg bw/day BPA through daily, noninvasive oral administration of dosed-cookies to the dams. Offspring were reared to adulthood. Their brains were collected and immunolabeled for tyrosine hydroxylase (TH) in the AVPV and calbindin (CALB) in the SDN-POA. We observed decreased TH-ir cell numbers in the female AVPV across all exposure groups, an effect indicative of masculinization. In males, AVPV TH-ir cell numbers were significantly reduced in only the BPA 10 and BPA 10,000 groups. SDN-POA endpoints were unaltered in females but in males SDN-POA volume was significantly lower in all BPA exposure groups. CALB-ir was significantly lower in all but the BPA 1000 group. These effects are consistent with demasculinization. Collectively these data demonstrate that early life oral exposure to BPA at levels well below the current No Observed Adverse Effect Level (NOAEL) of 50 mg/kg/day can alter sex specific hypothalamic morphology in the rat. PMID:23500335

  3. Training for Better Management: Avante Zambézia, PEPFAR and Improving the Quality of Administrative Services

    PubMed Central

    Schwarcz, Sandra K.; Rutherford, George W.; Horvath, Hacsi

    2015-01-01

    The United States President’s Emergency Plan for AIDS Relief (PEPFAR) emphasizes health systems strengthening as a cornerstone of programmatic success. Health systems strengthening, among other things, includes effective capacity building for clinical care, administrative management and public health practice. Avante Zambézia is a district-level in-service training program for administrative staff. It is associated with improved accounting practices and human resources and transportation management but not monitoring and evaluation. We discuss other examples of successful administrative training programs that vary in the proportion of time that is spent learning on the job and the proportion of time spent in classrooms. We suggest that these programs be more rigorously evaluated so that lessons learned can be generalized to other countries and regions. PMID:26673340

  4. Maintain School Discipline. Module LT-C-3 of Category C--Student Services. Competency-Based Vocational Education Administrator Module Series.

    ERIC Educational Resources Information Center

    Harrington, Lois G.; And Others

    This module, one in a series of competency-based administrator instructional packages, focuses on a specific competency that vocational education administrators need to be successful in the area of student services. The purpose of the module is to help the administrator develop skill in creating a climate conducive to discipline and in instituting…

  5. 77 FR 749 - General Services Administration Acquisition Regulation; Implementation of Information Technology...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-06

    ... CONTACT: Ms. Deborah Lague, Procurement Analyst, at (202) 694-8149, for clarification of content. For... recommendation and published an interim rule in the Federal Register at 76 FR 34886 on June 15, 2011, with a... Product Service Code D--ADP and Telecommunication Services. The requirements of the plan apply to all...

  6. 42 CFR 484.14 - Condition of participation: Organization, services, and administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION HOME HEALTH SERVICES... budget that includes an annual operating budget and capital expenditure plan. (1) Annual operating budget... identification of the components of each type of anticipated income or expense. (2) Capital expenditure plan....

  7. 20 CFR 655.625 - Written notice, service and Federal Register publication of Administrator's determination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... perform longshore activity(ies) in a U.S. port (whether the Administrator's investigation involves an.... The notice shall identify the activity(ies), the U.S. port, and the prevailing practice regarding...

  8. 20 CFR 655.625 - Written notice, service and Federal Register publication of Administrator's determination.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... perform longshore activity(ies) in a U.S. port (whether the Administrator's investigation involves an.... The notice shall identify the activity(ies), the U.S. port, and the prevailing practice regarding...

  9. 20 CFR 655.625 - Written notice, service and Federal Register publication of Administrator's determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... perform longshore activity(ies) in a U.S. port (whether the Administrator's investigation involves an.... The notice shall identify the activity(ies), the U.S. port, and the prevailing practice regarding...

  10. Are we preparing health services administration students to respond to bioterrorism and mass casualty management?

    PubMed

    Houser, Shannon H; Houser, Howard W

    2006-01-01

    Bioterrorism/natural disaster events add significant specialized demands and disrupt normal operation of the health system, often for an indefinite period of time. Health administration leaders should be educationally prepared for and informed about these potential events, but few receive this knowledge via their academic preparation in health administration. This study examined the existence of coverage of bioterrorism topics in health administration curricula and characteristics of bioterrorism coverage in current health administration programs through a self-completed survey among AUPHA graduate and undergraduate program members. Of the total survey respondents, only 32% of programs have current coverage of bioterrorism. The main reasons for nothavingbioterrorism coverage were not having enough resources; not having enough time to develop course/materials; and not thinking it is necessary to add these courses/materials. To prepare better and to inform future health administrators regarding major disruptive circumstances, advocacy and documentation are important to develop and implement bioterrorism awareness. Possibly, suggested minimum curricular requirements, content, and mechanisms for inclusion can be developed in the near future. Health administration educators should address the new reality and demonstrate that their graduates can function and lead in crises and situations disruptive to normal commerce.

  11. Proposed Revenues, Financial Strategy, and Program Costs for FY 1992 and 1993 : Technical Appendix, BPA Programs in Perspective.

    SciTech Connect

    United States. Bonneville Power Administration.

    1990-07-01

    Programs in Perspective is the Bonneville Power Administration's public involvement process (PIP) for engaging customers and other stakeholders in a regional dialog to set strategic direction and broad program plans for BPA effort. This planning leads into a biennial rate setting cycle and offers a more accessible and flexible opportunity for dialog on broad issues than is possible under the strict administrative procedures of ratemaking. The self-financed character of BPA has made this public process a necessary and valuable one to assure that those who pay BPA's rates have a clear understanding and a strong voice in the plans for use of the resulting revenues. During 1989, the previous PIP engaged the region in discussion of major strategic, issues focussing on major areas. In 1990, BPA seeks discussion of the directions and plans specifically for fiscal years 1992 and 1993. The steps taken for those years will lay the foundation for the years beyond. Thus, we have subtitled this year's process, Staying fit for the long run.'' We have consulted extensively with customers and others in the region in developing these plans. In dozens of program--specific meetings, BPA staff have talked and listened to what others think our plans ought to be. PIP now gives us a chance to review their sum total, along with projections for revenues and our overall financial position. 8 tabs., 8 figs.

  12. 42 CFR 485.918 - Condition of participation: Organization, governance, administration of services, and partial...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) STANDARDS AND CERTIFICATION CONDITIONS OF PARTICIPATION: SPECIALIZED PROVIDERS Conditions of Participation... been discharged from an inpatient mental health facility. (a) Standard: Governing body and... management of the CMHC, the services it furnishes, its fiscal operations, and continuous quality...

  13. The Role of the Administrator in the Community Services/Continuing Education Program.

    ERIC Educational Resources Information Center

    Thomas, Thomas K.

    1985-01-01

    Suggests ways that community services/continuing education programs can maintain their visibility, integrity, currentness, and flexibility. Sees proper marketing both within and without the institution as important means of ensuring the continued expansion of credibility. (DMM)

  14. Managing transition: guidelines for mental health administrators facing services retrenchment due to funding cuts.

    PubMed

    Raymond, J S

    1983-01-01

    This piece of writing is one part of a four part series on managing transition in turbulent times. The series is written for mental health administrators and is a product of the author's direct experience as chief administrator of addiction treatment facilities and programs for The Salvation Army in Hawaii. Despite the loss of several hundred thousands of dollars, the agency was able to manage its own transition to emerge stronger and with two full years of accreditation as a psychiatric facility by the prestigious Joint Commission on the Accreditation of Hospitals.

  15. 9 CFR 72.18 - Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... treatment required when dipping facilities unavailable. (a) Tick-infested cattle. Cattle of the free area which are tick-infested may be moved interstate for any purpose after they have been treated in the same... Administrator, APHIS. (b) Tick-exposed cattle. Cattle of the free area which have been exposed to...

  16. 47 CFR 54.701 - Administrator of universal service support mechanisms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... § 54.705: (1) the Schools and Libraries Committee, which shall oversee the schools and libraries... Administrator shall establish three divisions: (i) The Schools and Libraries Division, which shall perform duties and functions in connection with the schools and libraries support mechanism under the...

  17. 42 CFR 418.100 - Condition of Participation: Organization and administration of services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... goals, with patient needs and goals as priority. (b) Standard: Governing body and administrator. A governing body (or designated persons so functioning) assumes full legal authority and responsibility for... reporting to the governing body is responsible for the day-to-day operation of the hospice....

  18. 42 CFR 418.100 - Condition of Participation: Organization and administration of services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... goals, with patient needs and goals as priority. (b) Standard: Governing body and administrator. A governing body (or designated persons so functioning) assumes full legal authority and responsibility for... reporting to the governing body is responsible for the day-to-day operation of the hospice....

  19. Pre-Service, Professional Development, and Collaborative Practices Regarding Paraprofessionals, Special Education Teachers, and Administrators

    ERIC Educational Resources Information Center

    Beddow-Beste, Jolaine

    2012-01-01

    Administrators, teachers, and paraprofessionals play an important role in successful outcomes for students with special needs. Post-secondary training does not guarantee that emphasis is put on how each professional entity maintains the ability to collaborate with one another, and how to determine what continued training is pertinent for each of…

  20. 77 FR 69768 - General Services Administration Acquisition Regulation (GSAR); Rewrite of Part 504...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... (GSA) published a document in the Federal Register on October 1, 2012 (77 FR 59790), revising... published in the Federal Register at 77 FR 59790 on October 1, 2012 contained a typographical error. This...); Rewrite of Part 504, Administrative Matters; Correction AGENCY: Office of Acquisition Policy,...

  1. Institutional Innovation and Public Extension Services Provision: The Marche Regional Administration Reform in Central Italy

    ERIC Educational Resources Information Center

    Pascucci, Stefano; De Magistris, Tiziana

    2011-01-01

    This paper describes how Marche Regional Administration (MRA) introduced an innovative institutional reform of an Agricultural Knowledge and Information System (AKIS) in central Italy. In order to study the main features of the MRA reform we used a methodological approach based on three steps: (i) first we applied a desk analysis to sketch the…

  2. 75 FR 77921 - Office of Administrative Services; Mandatory Declassification Review Address

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ... (National Archives and Records Administration) --Federal Register Notice 75 FR 707, ``Classified National Security Information'' (January 5, 2010) --Federal Register Notice 75 FR 37254, ``32 CFR Parts 2001 and... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE...

  3. Task Force Report on HIV/AIDS and Health Services Administration Education.

    ERIC Educational Resources Information Center

    Dunham, Nancy Cross

    In November 1987, a task force met to review the major organizational, structural, and policy-related issues for health care administration professionals related to the growing impact of Acquired Immune Deficiency Syndrome (AIDS) on the health care delivery system and to make recommendations on the training needs of persons within the health care…

  4. Legal Issues in School Health Services and School Psychology: Guidelines for the Administration of Medication

    ERIC Educational Resources Information Center

    Mazur-Mosiewicz, Anna; Pierson, Eric E.; McIntosh, David E.

    2009-01-01

    The use of psychoactive medications to augment behavioral and psychosocial interventions in schools has significantly increased within the last few decades. Yet, advising, administrating, and supervising the dispensation of medication (including psychostimulants and psychoactive substances) tend to be some of the most risky tasks of school…

  5. Structuring the Administrative Organization of Local School Systems. Educational Research Service Circular No. 2.

    ERIC Educational Resources Information Center

    American Association of School Administrators, Washington, DC.

    This paper is intended to assist school administrators in improving existing school organizations. It discusses the nature of organizations, provides indicators of reorganization timing, and discusses the task of reorganization. A matrix chart, used to analyze and compare different organizational structures, is provided with explanations.…

  6. Neonatal Neurocritical Care Service Is Associated With Decreased Administration of Seizure Medication.

    PubMed

    Wietstock, Sharon O; Bonifacio, Sonia L; McCulloch, Charles E; Kuzniewicz, Michael W; Glass, Hannah C

    2015-08-01

    This cohort study examines medication use in term neonates with hypoxic-ischemic encephalopathy and seizures before and after implementation of a Neonatal Neurocritical Care Service (N = 108), which included increased seizure monitoring. Nearly all neonates received phenobarbital (96% pre- vs 95% post-Neonatal Neurocritical Care Service) and total loading dose did not vary among groups (33 [95% confidence interval 29-37] vs 30 [26-34] mg/kg). After adjustment for seizure burden, neonates managed during the Neonatal Neurocritical Care Service era, on average, received 30 mg/kg less cumulative phenobarbital (95% confidence interval 15-46 mg/kg) and were on maintenance 5 fewer days (95% confidence interval 3-8 days) than those who were treated prior to implementation of the service. In spite of the enhanced ability to detect seizures because of improved monitoring and increased vigilance by bedside practitioners, implementation of the Neonatal Neurocritical Care Service was associated with decreased use of potentially harmful phenobarbital treatment among neonates with hypoxic-ischemic encephalopathy. PMID:25380602

  7. Neonatal neurocritical care service is associated with decreased administration of seizure medication

    PubMed Central

    Wietstock, Sharon O; Bonifacio, Sonia L; McCulloch, Charles E; Kuzniewicz, Michael W; Glass, Hannah C

    2014-01-01

    This cohort study examines medication use in term neonates with hypoxic-ischemic encephalopathy (HIE) and seizures before and after implementation of a Neonatal Neurocritical Care Service (N=108), which included increased seizure monitoring. Nearly all neonates received phenobarbital (96% pre- versus 95% post-Neonatal Neurocritical Care Service) and total loading dose did not vary among groups (33 [95% CI 29–37] versus 30 [26–34] mg/kg). After adjustment for seizure burden, neonates managed during the Neonatal Neurocritical Care Service era, on average, received 30 mg/kg less cumulative phenobarbital (95% CI 15–46 mg/kg) and were on maintenance 5 fewer days (95% CI 3–8 days) than those who were treated prior to implementation of the service. In spite of the enhanced ability to detect seizures due to improved monitoring and increased vigilance by bedside practitioners, implementation of the Neonatal Neurocritical Care Service was associated with decreased use of potentially harmful phenobarbital treatment among neonates with HIE. PMID:25380602

  8. Commercial ELV services and the National Aeronautics and Space Administration - Concord or discord?

    NASA Technical Reports Server (NTRS)

    Frankle, Edward A.

    1988-01-01

    In implementation of the U.S. policy to foster and encourage the commercial expendable launch vehicle (ELV) industry, tensions have developed between the industry and U.S. Government agencies in two distinct areas: industry use of government facilities and government purchase of commercial ELV services. The reasons for the tensions and discrete legal problems for each area are identified and discussed. Specifically, in the use of government facilities area, issues of insurance and indemnification for third-party liability and government property, concerns over priority and scheduling, and dispute-resolution procedures are discussed. In the area of government purchase of ELV launch services, a comparison is made between a launch service purchase and prior procurement practice. In all areas, the conclusion is reached that while problems still exist, they generally are understood and great progress has been made toward their resolution.

  9. Education for Health Services Administration in the United Kingdom. Program Notes, Number 66.

    ERIC Educational Resources Information Center

    White, Donald K., Ed.

    International comparative studies are justified because they can increase the options among which health care decision makers may select approaches suitable to their own circumstances. The collection of papers on management education and training in the National Health Service in the United Kingdom presents a summary of the salient features of the…

  10. 77 FR 76446 - General Services Administration Acquisition Regulation (GSAR); Industrial Funding Fee (IFF) and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ...); Industrial Funding Fee (IFF) and Sales Reporting AGENCY: Office of Acquisition Policy, General Services... address the use of the Industrial Funding Fee (IFF) under the Multiple Award Schedules (MAS) Program. The... Provisions and Contract Clauses at 552.238- 74 Industrial Funding Fee and Sales Reporting. Currently,...

  11. Professors, Administrators at U. of Portland Get a Firsthand Look at Services to City's Poor.

    ERIC Educational Resources Information Center

    Monaghan, Peter

    1987-01-01

    Professors and staff members of the University of Portland took the "urban plunge" when they visited the state's Adult and Family Services offices, shelters for the homeless and for battered women, an alcohol- and drug-rehabilitation center, and served lunch at two soup kitchens. A project at Notre Dame is also described. (MLW)

  12. 77 FR 74631 - General Services Administration Acquisition Regulation: Modifications (Multiple Award Schedules...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... (Multiple Award Schedules); Information Collection AGENCY: Office of Acquisition Policy, General Services... Modifications (Multiple Award Schedule). DATES: Submit comments on or before: February 15, 2013. FOR FURTHER... Acquisition Regulation (GSAR) to add clause 552.243-72; Modifications (Multiple Award Schedules). Under...

  13. 77 FR 74191 - Information Collection; Proposed Collection; Comment Request; General Services Administration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES... regarding an existing information collection. SUMMARY: As part of a Federal Government wide effort to....gov : http://www.regulations.gov . Submit comments via the Federal eRulemaking portal by searching...

  14. 77 FR 36543 - General Services Administration Acquisition Regulation (GSAR) Part 523; Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... items of hazardous material allows for appropriate handling of such items throughout GSA's supply chain..., Procurement Analyst, General Services Acquisition Policy Division, GSA, at telephone (202) 357-5846 or via... comments via the Federal eRulemaking portal by searching the OMB control number. Select the link ``Submit...

  15. 77 FR 59613 - General Services Administration Acquisition Regulation (GSAR) Part 523; Submission for OMB Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... items of hazardous material allows for appropriate handling of such items throughout GSA's supply chain..., Occupational Safety, and Drug- Free Workplace. A notice was published in the Federal Register at 77 FR 36543... Gasbarra, Procurement Analyst, General Services Acquisition Policy Division, GSA, at telephone...

  16. 9 CFR 72.18 - Movement interstate; specification by the Deputy Administrator, Veterinary Services of treatment...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... unavailable. 72.18 Section 72.18 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Movement interstate; specification...

  17. 78 FR 18981 - General Services Administration Acquisition Regulation; Submission for OMB Review; Proposal to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ....gov . Submit comments via the Federal eRulemaking portal by searching for ``Information Collection... information provided. FOR FURTHER INFORMATION CONTACT: Ms. Kathy Rifkin, Procurement Analyst, General Services... result of the reform, five new lease contract models have been developed that are targeted to meet...

  18. 78 FR 73863 - Public Availability of General Services Administration FY 2013 Federal Activities Inventory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ... the Federal Activities Inventory Reform (FAIR) Act of 1998, Public Law 105-270, and Office of.... Paul F. Boyle in the Office of Acquisition Policy at 202-501-0324 or gsa.gov ">Paul.Boyle@ gsa.gov... Law 105-270, and Office of Management and Budget (OMB) Circular A-76, General Services...

  19. A Study of Coordinated Service Provision and Administrative Procedures in Selected University Communities.

    ERIC Educational Resources Information Center

    Clemson Univ., SC. Strom Thurmond Inst. of Government and Public Affairs.

    This study investigated the existence of coordinated/consolidated services between colleges and universities and their communities by surveying 27 university communities of similar size and/or characteristics to Clemson University (South Carolina). The report begins with the profiles of the universities selected: their size in acreage, enrollment,…

  20. The Challenges of Creating a Benchmarking Process for Administrative and Support Services

    ERIC Educational Resources Information Center

    Manning, Terri M.

    2007-01-01

    In the current climate of emphasis on outcomes assessment, colleges and universities are working diligently to create assessment processes for student learning outcomes, competence in general education, student satisfaction with services, and electronic tracking media to document evidence of competence in graduates. Benchmarking has become a…

  1. Library of Michigan FY 2002 Library Services and Technology Act (LSTA) Grant Administration Handbook.

    ERIC Educational Resources Information Center

    Michigan Library, Lansing.

    This handbook provides FY (fiscal year) 2002 guidelines developed by the Library of Michigan for administering LSTA (Library Services and Technology Act) grants. The first section provides an overview of the LSTA program. The second section gives the grant timeline for FY 2002. The third section describes the award process, including award…

  2. 77 FR 76446 - General Services Administration Acquisition Regulation (GSAR); GSAR Case 2006-G507; Rewrite of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... at 74 FR 4596, January 26, 2009. There were 36 public comments received in response to the Advanced...; Subpart 538.19, FSS and Small Business Programs; Subpart 538.25, Requirements for Foreign Entities... addressed in the GSAR Part 538 Rewrite, and strong stakeholder interest, the General Services...

  3. Health maintenance organizations; Midwest Health Plan--Health Resources and Services Administration.

    PubMed

    1983-04-26

    On January 21, 1983, the Office of Health Maintenance Organizations (OHMO) notified Midwest Health Plan (MHP), 3415 Bridgeland Drive, Bridgeton, Missouri 63044, a federally qualified health maintenance organization (HMO), that MHP had successfully reestablished compliance with its assurances to the Secretary that it would (1) maintain a fiscally sound operation, and (2) maintain satisfactory administrative and managerial arrangements. This determination took effect on January 1, 1983. PMID:10324428

  4. Power Subscription Strategy: Administrator`s Record of Decision.

    SciTech Connect

    United States. Bonneville Power Administration

    1998-12-01

    The Bonneville Power Administration (BPA) has decided to adopt a Power Subscription Strategy for entering into new power sales contracts with its Pacific Northwest customers. The Strategy equitably distributes the electric power generated by the Federal Columbia River Power System (FCRPS) within the framework of existing law. The Power Subscription Strategy addresses the availability of power; describes power products; lays out strategies for pricing, including risk management; and discusses contract elements. In proceeding with this Subscription Strategy, BPA is guided by and committed to the Fish and Wildlife funding Principles for the BPA announced by the Vice President of the US in September 1998. This Record of Decision (ROD) addresses the issues raised by commenters who responded to BPA`s Power Subscription Strategy Proposal during and after the comment period that began with the release of the Proposal on September 18, 1998. The ROD is organized in approximately the same way as the Proposal and the Power Subscription Strategy that BPA developed based on the comments received. Abbreviations of party names used in citations appear in the section just preceding this introduction; a list of all the commenters follows the text of the ROD.

  5. Realising opportunities for evidence-based cancer service delivery and research: linking cancer registry and administrative data in Australia.

    PubMed

    Roder, D M; Fong, K M; Brown, M P; Zalcberg, J; Wainwright, C E

    2014-11-01

    The traditional roles of Australian cancer registries have been incidence, mortality and survival surveillance although increasingly, roles are being broadened to include data support for health-service management and evaluation. In some Australian jurisdictions, cancer stage and other prognostic data are being included in registry databases and this is being facilitated by an increase in structured pathology reporting by pathology and haematology laboratories. Data linkage facilities are being extended across the country at national and jurisdictional level, facilitating data linkage between registry data and data extracts from administrative databases that include treatment, screening and vaccination data, and self-reported data from large population cohorts. Well-established linkage protocols exist to protect privacy. The aim is to gain better data on patterns of care, service outcomes and related performance indicators for health-service management and population health and health-services research, at a time of increasing cost pressures. Barriers include wariness among some data custodians towards releasing data and the need for clearance for data release from large numbers of research ethics committees. Progress is being made though, and proof of concept is being established.

  6. Computer learning strategies and outcomes: a field test in health services administration.

    PubMed

    Reutzel, T J; Smorynski, H W

    1986-01-01

    Decisions in the changing, competitive and highly complex health care market must be arrived at faster. The argument for the extensive use of computers by modern health care executives and the inclusion of computer training in the health administration curriculum rests on the fact that the survival and growth of health care institutions is vitally tied to the capacity of their managers to absorb increasingly complex data and turn it rapidly into usable information. Although educators cannot solve all health care industry implementation problems either as consultants or as analysis in implementation studies, they must provide clear direction in the analytical training of future managers concerning computer utilization and management information systems generally. Without the basic foundation in knowledge, attitude, and behavior reinforcement, the risk of improper and insufficient computer utilization in the industry is large. This article examines the curricular structure, learning theory, and preliminary student learning and behavior outcomes of a course developed in 1985 for health administration students at Sangamon State University.

  7. Directing the Cooperative Extension Service. Selected Papers Presented at the National Cooperative Extension Administrative Seminar (7th, Madison, Wisconsin, April 30-May 4, 1962).

    ERIC Educational Resources Information Center

    Clark, Robert C., Ed.; Ralston, N. P., Ed.

    The book provides administrators and students of administration with a background of extension programs of the past, the principles of large scale organization, and staff role in attaining extension goals. In Part 1, Changing Goals of the Cooperative Extension Service, C. M. Ferguson, Professor, University of Wisconsin, speaks on "Changing…

  8. Graduate Education in Political Science, in Traditional Public Administration and in the Emerging Public Management Approach: A Comparison of the Relevance of Each to Public Service Career Preparation.

    ERIC Educational Resources Information Center

    Boynton, Robert Paul; Lehnen, Robert G.

    Three approaches to public administration are analyzed in light of their contributions to preparation for careers in public service. The approaches are graduate education in political science, traditional public administration training, and public management. The three types of programs stress different subject matter and have different…

  9. [Research on characteristic of interrelationship between toxic organic compound BPA and Chlorella vulgaris].

    PubMed

    Chen, Shan-Jia; Chen, Xiu-Rong; Yan, Long; Zhao, Jian-Guo; Zhang, Fei; Jiang, Zi-Jian

    2014-04-01

    The effects of different concentrations of bisphenol A (BPA) on Chlorella vulgaris and removal capacity of BPA by Chlorella vulgaris were investigated. Results showed that a low concentration (0-20 mg x L(-1)) of BPA promoted the growth of Chlorella vulgaris, whereas a relative high concentration (20-50 mg x L(-1)) of BPA inhibited the growth of Chlorella vulgaris, and the inhibition effect was positively correlated with the concentration of BPA. Likewise, a high dose of initial BPA (> 20 mg x L(-1)) led to a decline in the content of chlorephyll a. Chlorella vulgaris had BPA removal capacity when initial BPA concentration ranged from 2 mg x L(-1) to 50 mg x L(-1). There was positive correlation between the removal rate of BPA per cell and initial BPA concentration. The removal rate of BPA was the highest when initial BPA was 50 mg x L(-1), which appeared between lag phase and logarithmic phase.

  10. Administration of care to older patients in transition from hospital to home care services: home nursing leaders’ experiences

    PubMed Central

    Dale, Bjørg; Hvalvik, Sigrun

    2013-01-01

    Background Older persons in transition between hospital and home care services are in a particularly vulnerable situation and risk unfortunate consequences caused by organizational inefficiency. The purpose of the study reported here was to elucidate how home nursing leaders experience the administration of care to older people in transition from hospital to their own homes. Methods A qualitative study design was used. Ten home nursing leaders in two municipalities in southern Norway participated in individual interviews. The interview texts were audio taped, transcribed verbatim and analyzed by use of a phenomenological-hermeneutic approach. Results Three main themes and seven subthemes were deduced from the data. The first main theme was that the home nursing leaders felt challenged by the organization of home care services. Two subthemes were identified related to this. The first was that the leaders lacked involvement in the transitional process, and the second was that they were challenged by administration of care being decided at another level in the municipality. The second main theme found was that the leaders felt that they were acting in a shifting and unsettled context. Related to this, they had to adjust internal resources to external demands and expectations, and experienced lack of communication with significant others. The third main theme identified was that the leaders endeavored to deliver care in accordance with professional values. The two related subthemes were, first, that they provided for appropriate internal systems and routines, and, second, that they prioritized available professional competence, and made an effort to promote a professional culture. Conclusion To meet the complex needs of the patients in a professional way, the home nursing leaders needed to be flexible and pragmatic in their administration of care. This involved utilizing available professional competence appropriately. The coordination and communication between the

  11. Army Active Duty Members' Linkage to Veterans Health Administration Services After Deployments to Iraq or Afghanistan and Following Separation.

    PubMed

    Vanneman, Megan E; Harris, Alex H S; Chen, Cheng; Mohr, Beth A; Adams, Rachel Sayko; Williams, Thomas V; Larson, Mary Jo

    2015-10-01

    This study described the rate and predictors of Operation Enduring Freedom/Operation Iraqi Freedom active duty Army members' enrollment in and use of Veterans Health Administration (VHA) services (linkage), as well as variation in linkage rates by VHA facility. We used a multivariate mixed effect regression model to predict linkage to VHA, and also calculated linkage rates in the catchment areas of each facility (n = 158). The sample included 151,122 active duty members who deployed to Iraq or Afghanistan and then separated from the Army between fiscal years 2008 and 2012. Approximately 48% of the active duty members separating utilized VHA as an enrollee within one year. There was significant variation in linkage rates by VHA facilities (31-72%). The most notable variables associated with greater linkage included probable serious injury during index deployment (odds ratio = 1.81), separation because of disability (odds ratio = 2.86), and various measures of receipt of VHA care before and after separation. Information about the individual characteristics that predict greater or lesser linkage to VHA services can be used to improve delivery of health care services at VHA as well as outreach efforts to active duty Army members. PMID:26444467

  12. BPA Committed to Northwest Values

    SciTech Connect

    2010-09-01

    The Columbia River has been called the “crown jewel” of the Pacific Northwest. There is no question it is among the region’s greatest assets — supplying low-cost clean hydropower, making deserts bloom thanks to irrigation and providing navigation, recreation and a home for many species of fish and wildlife. The Bonneville Power Administration is proud to be a steward of this great resource. Our mission is to serve the people and environment of the Pacific Northwest. We sell wholesale power from Grand Coulee Dam and 30 other Northwest federal dams to Northwest utilities, including public utility districts, rural electric cooperatives and municipal utility departments, as well as investor-owned utilities. We operate three-fourths of the region’s high voltage transmission system that delivers that power. But, as a federal agency, we are not just a power marketer. We have public responsibilities that include, among many, promoting energy efficiency, facilitating development of renewable power, protecting fish and wildlife affected by hydro development, honoring treaty obligations to tribes and promoting a reliable energy future through collaboration and partnerships. This document describes our responsibilities to citizens in the Pacific Northwest.

  13. What explains the quality and price of GP services? An investigation using linked survey and administrative data.

    PubMed

    Johar, Meliyanni; Jones, Glenn; Savage, Elizabeth

    2014-09-01

    We examine patient socioeconomic status, the strength of the patient-doctor relationship and local area competition as determinants of the quality and price of GP services. We exploit a large-sample patient data set in Australia and its linkage to administrative databases. The sample contains over 260,000 patients and over 12,600 GPs, observed between 2005 and 2010. Controlling for GP fixed effects and patient health, we find no strong evidence that quality differs by patient age, gender, country of origin, health concession card status and income, but quality is increased by stronger patient-doctor relationship. Using a competition measure that is defined at the individual GP level and not restricted to a local market, we find that competition lowers quality. Price is increasing in patient income, whereas competition has a small impact on price.

  14. Wide-Area Energy Storage and Management system to Balance Intermittent Resources in the Bonneville Power Administration and California ISO Control Areas

    SciTech Connect

    Makarov, Yuri V.; Yang, Bo; DeSteese, John G.; Lu, Shuai; Miller, Carl H.; Nyeng, Preben; Ma, Jian; Hammerstrom, Donald J.; Vishwanathan, Vilanyur V.

    2008-06-30

    The entire project addresses the issue of mitigating additional intermittency and fast ramps that occur at higher penetration of intermittent resources, including wind genera-tion, in the Bonneville Power Administration (BPA) and the California Independent Sys-tem Operator (California ISO) control areas. The proposed Wide Area Energy Storage and Management System (WAEMS) will address the additional regulation requirement through the energy exchange between the participating control areas and through the use of energy storage and other generation resources. For the BPA and California ISO control centers, the new regulation service will look no different comparing with the traditional regulation resources. The proposed project will benefit the regulation service in these service areas, regardless of the actual degree of penetration of the intermittent resources in the regions. The project develops principles, algorithms, market integration rules, functional de-sign and technical specifications for the WAEMS system. The project is sponsored by BPA and supported in kind by California ISO, Beacon Power Corporation, and the Cali-fornia Energy Commission (CEC).

  15. Opportunities and Barriers to Rural, Remote and First Nation Health Services Research in Canada: Comparing Access to Administrative Claims Data in Manitoba and British Columbia.

    PubMed

    Lavoie, Josée G; Wong, Sabrina; Katz, Alan; Sinclair, Stephanie

    2016-08-01

    Access to geographically disaggregated data is essential for the pursuit of meaningful rural, remote and First Nation health services research. This paper explores the opportunities and challenges associated with undertaking administrative claims data research in the context of two different models of administrative data management: the Manitoba and British Columbia models. We argue that two conditions must be in place to support rural, remote and First Nation health services research: (1) pathways to data access that reconcile the need to protect privacy with the imperative to conduct analyses on disaggregated data; and (2) a trust-based relationship with data providers. PMID:27585026

  16. Opportunities and Barriers to Rural, Remote and First Nation Health Services Research in Canada: Comparing Access to Administrative Claims Data in Manitoba and British Columbia.

    PubMed

    Lavoie, Josée G; Wong, Sabrina; Katz, Alan; Sinclair, Stephanie

    2016-08-01

    Access to geographically disaggregated data is essential for the pursuit of meaningful rural, remote and First Nation health services research. This paper explores the opportunities and challenges associated with undertaking administrative claims data research in the context of two different models of administrative data management: the Manitoba and British Columbia models. We argue that two conditions must be in place to support rural, remote and First Nation health services research: (1) pathways to data access that reconcile the need to protect privacy with the imperative to conduct analyses on disaggregated data; and (2) a trust-based relationship with data providers.

  17. Opportunities and Barriers to Rural, Remote and First Nation Health Services Research in Canada: Comparing Access to Administrative Claims Data in Manitoba and British Columbia

    PubMed Central

    Wong, Sabrina; Katz, Alan; Sinclair, Stephanie

    2016-01-01

    Access to geographically disaggregated data is essential for the pursuit of meaningful rural, remote and First Nation health services research. This paper explores the opportunities and challenges associated with undertaking administrative claims data research in the context of two different models of administrative data management: the Manitoba and British Columbia models. We argue that two conditions must be in place to support rural, remote and First Nation health services research: (1) pathways to data access that reconcile the need to protect privacy with the imperative to conduct analyses on disaggregated data; and (2) a trust-based relationship with data providers. PMID:27585026

  18. SAVEnergy Action Plan: National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northwest Fisheries Science Center, Seattle, Washington

    SciTech Connect

    Parker, S.A.; Wahlstrom, R.R.; Richman, E.E.; Sandusky, W.F. III; Dittmer, A.L.

    1995-05-01

    The Pacific Northwest Laboratory (PNL) conducted a SAVEnergy Audit of the National Oceanic and Atmospheric Administration`s (NOAA) National Marine Fisheries Service, Northwest Fisheries Science Center in Seattle, Washington. The objectives of this study were to evaluate the performance of all energy-consuming equipment in the facility, to estimate energy consumption and demand by end-use and to recommend energy conservation measures (ECMs) and water conservation measures (WCMs) to reduce costs . This section describes the facility and the systems encountered during the visit by the audit team. It also presents a summary of energy conservation measures. Section 2 shows energy consumption and costs for electricity, natural gas and water. A breakdown of energy consumed by end-use is also presented. Recommended energy conservation measures are presented in Section 3. Section 4 contains a discussion of operations and maintenance issues and other energy measures that can be implemented on a replace-on-failure basis rather than replacing immediately. Appendix A contains a three-year history of consumption, demand and cost for electric, natural gas and water utilities. Appendix B contains information on local weather data correlated to utility billing periods. A brief summary on Federal life-cycle costing is located in Appendix C along with the life-cycle cost analyses summaries for the energy and water conservation measures detailed in this report. Information on the rebate program sponsored by Seattle City Light, the electric utility, is located in Appendix D. Sample information for water-efficient equipment is located in Appendix E. Appendix F contains submittal forms to the Federal Energy Efficiency Fund for the energy conservation measures recommended in Section 3 of this report. A glossary of terms and abbreviations used in this report is located in Appendix G.

  19. Rehabilitation Services Administration

    MedlinePlus

    ... from RSA More at RSA.ED.GOV Workforce Innovation and Opportunity Act ( WIOA ) Final Rules The Office ... of the following final rules implementing the Workforce Innovation and Opportunity Act ( WIOA ). WIOA : Joint Rule for ...

  20. Administrative Support Services.

    ERIC Educational Resources Information Center

    Heterick, Robert C.

    1981-01-01

    The opportunities for improved internal communication through the use of information technology are discussed. A case is made for the leverage gained by investing in computer-based, information technology. Potential impacts on physical space, staff productivity, circulation patterns, and organizational structure are suggested. (Author/MLW)

  1. Bonneville, Power Administration Timing System

    NASA Technical Reports Server (NTRS)

    Martin, Kenneth E.

    1996-01-01

    Time is an integral part of the Bonneville Power Administration's (BPA) operational systems. Generation and power transfers are planned in advance. Utilities coordinate with each other by making these adjustments on a timed schedule. Price varies with demand, so billing is based on time. Outages for maintenance are scheduled to assure they do not interrupt reliable power delivery. Disturbance records are aligned with recorded timetags for analysis and comparison with related information. Advanced applications like traveling wave fault location and real-time phase measurement require continuous timing with high precision. Most of BPA is served by a Central Time System (CTS) at the Dittmer Control Center near Portland, OR. This system keeps time locally and supplies time to both the control center systems and field locations via a microwave signal. It is kept synchronized to national standard time and coordinated with interconnected utilities. It is the official BPA time. Powwer system control and operation is described, followed by a description of BPA timing systems including CTS, the Fault Location Acquisition Reporter, time dissemination, and phasor measurements. References are provided for further reading.

  2. Health risk of exposure to Bisphenol A (BPA).

    PubMed

    Konieczna, Aleksandra; Rutkowska, Aleksandra; Rachoń, Dominik

    2015-01-01

    Bisphenol A (BPA) belongs to chemicals that are produced in large quantities worldwide. It is commonly used as monomer in polycarbonate synthesis, plasticizer in the production of epoxy resins, as well as an additive for the elimination of surfeit of hydrochloric acid during the polyvinyl chloride (PVC) production. BPA is not only used in the production of plastics intended to a direct contact with food, including plastic packaging and kitchenware, but also in inner coatings of cans and jar caps. There are various routes of human exposure to this substance such as oral, by inhalation and transdermal. The main sources of exposure to BPA include food packaging and dust, dental materials, healthcare equipment, thermal paper, toys and articles for children and infants. BPA is metabolized in the liver to form bisphenol A glucuronide and mostly in this form is excreted with urine. Due to its phenolic structure BPA has been shown to interact with estrogen receptors and to act as agonist or antagonist via estrogen receptor (ER) dependent signalling pathways. Therefore, BPA has been shown to play a role in the pathogenesis of several endocrine disorders including female and male infertility, precocious puberty, hormone dependent tumours such as breast and prostate cancer and several metabolic disorders including polycystic ovary syndrome (PCOS). Because of the constant, daily exposure and its tendency to bio-accumulation, BPA seems to require special attention such as biomonitoring. This observation should include clinical tests of BPA concentration in the urine, which is not only one of the best methods of evaluation of the exposure to this compound, but also the dependence of the daily intake of BPA and the risk of some endocrine disorders.

  3. Health risk of exposure to Bisphenol A (BPA).

    PubMed

    Konieczna, Aleksandra; Rutkowska, Aleksandra; Rachoń, Dominik

    2015-01-01

    Bisphenol A (BPA) belongs to chemicals that are produced in large quantities worldwide. It is commonly used as monomer in polycarbonate synthesis, plasticizer in the production of epoxy resins, as well as an additive for the elimination of surfeit of hydrochloric acid during the polyvinyl chloride (PVC) production. BPA is not only used in the production of plastics intended to a direct contact with food, including plastic packaging and kitchenware, but also in inner coatings of cans and jar caps. There are various routes of human exposure to this substance such as oral, by inhalation and transdermal. The main sources of exposure to BPA include food packaging and dust, dental materials, healthcare equipment, thermal paper, toys and articles for children and infants. BPA is metabolized in the liver to form bisphenol A glucuronide and mostly in this form is excreted with urine. Due to its phenolic structure BPA has been shown to interact with estrogen receptors and to act as agonist or antagonist via estrogen receptor (ER) dependent signalling pathways. Therefore, BPA has been shown to play a role in the pathogenesis of several endocrine disorders including female and male infertility, precocious puberty, hormone dependent tumours such as breast and prostate cancer and several metabolic disorders including polycystic ovary syndrome (PCOS). Because of the constant, daily exposure and its tendency to bio-accumulation, BPA seems to require special attention such as biomonitoring. This observation should include clinical tests of BPA concentration in the urine, which is not only one of the best methods of evaluation of the exposure to this compound, but also the dependence of the daily intake of BPA and the risk of some endocrine disorders. PMID:25813067

  4. ADMINISTRATIVE CLIMATE.

    ERIC Educational Resources Information Center

    BRUCE, ROBERT L.; CARTER, G.L., JR.

    IN THE COOPERATIVE EXTENSION SERVICE, STYLES OF LEADERSHIP PROFOUNDLY AFFECT THE QUALITY OF THE SERVICE RENDERED. ACCORDINGLY, MAJOR INFLUENCES ON ADMINISTRATIVE CLIMATE AND EMPLOYEE PRODUCTIVITY ARE EXAMINED IN ESSAYS ON (1) SOURCES OF JOB SATISFACTION AND DISSATISFACTION, (2) MOTIVATIONAL THEORIES BASED ON JOB-RELATED SATISFACTIONS AND NEEDS,…

  5. BPA uptake in rat tissues after partial hepatectomy

    SciTech Connect

    Slatkin, D.N.; Nawrocky, M.M.; Coderre, J.A.; Fisher, C.D.; Joel, D.D.; Lombardo, D.T.; Micca, P.L.

    1996-12-31

    In boron neutron capture therapy (BNCT), boron given as boronophenylalanine (BPA) accumulates transiently not only in tumors but also in normal tissues. Average boron concentrations in transplanted 9L gliosarcoma tumors of 20 rats were 2.5 to 3.7 times concentrations found in blood. Although boron levels in a variety of tissues were also higher than blood the concentrations were less than the lowest found in the tumor. Further note than although BPA is a structural analogue of phenylalanine (Phe), the pathway of BPA uptake into regenerating liver may not be linked to Phe uptake mechanisms.

  6. Career Pathing among General Administrative and Support Services Employees Based on Holland?s Typology of Personality Theory and Personal Style Inventory

    ERIC Educational Resources Information Center

    Mendoza, Catalino N.

    2009-01-01

    The study is about the prevailing differences, commonalities and significant contributions of the career pathing among the general administrative and support services employees based on Holland's Typology of Personality Theory and Personal Style Inventory of selected higher educational institutions in Metro Manila.

  7. Mountain-Plains Handbook: The Design and Operation of a Residential Family Based Education Program. Appendix. Supplement I to Volume 5. Operational Support: Administrative Services Division.

    ERIC Educational Resources Information Center

    Anderson, Newell B.; And Others

    One of two supplements which accompany chapter 5 of "Mountain-Plains Handbook: The Design and Operation of a Residential, Family Oriented Career Education Model" (CE 014 630), this document contains specific information concerning the reprographic and personnel components of the administrative services division. Several job descriptions and sample…

  8. Impact of Federal Legislation and Policy on VR Services for Consumers Who Are Deaf or Hard of Hearing: Perspectives of Agency Administrators and Program Specialists

    ERIC Educational Resources Information Center

    Anderson, Glenn B.; Boone, Steven E.; Watson, Douglas

    2003-01-01

    The authors report on a national survey of administrators and program specialists at 43 state vocational rehabilitation (VR) agencies concerning the impact of federal employment legislation and rehabilitation policies on the provision of services to consumers who are deaf or hard of hearing. The article focuses on 5 initiatives enacted to enhance…

  9. Practical and Policy Implications of Using Different Rural-Urban Classification Systems: A Case Study of Inpatient Service Utilization among Veterans Administration Users

    ERIC Educational Resources Information Center

    Berke, Ethan M.; West, Alan N.; Wallace, Amy E.; Weeks, William B.

    2009-01-01

    Context: Several classification systems exist for defining rural areas, which may lead to different interpretations of rural health services data. Purpose: To compare rural classification systems on their implications for estimating Veterans Administration (VA) utilization. Methods: Using 7 classification systems, we counted VA health care…

  10. Mountain-Plains Handbook: The Design and Operation of a Residential Family Based Education Program. Appendix. Supplement II to Volume 5. Operational Support: Administrative Services Division.

    ERIC Educational Resources Information Center

    Anderson, Newell B.; And Others

    One of two supplements which accompany chapter 5 of "Mountain-Plains Handbook: The Design and Operation of a Residential, Family Oriented Career Education Model" (CE 014 630), this document contains specific information concerning the following components of the administrative services division: purchasing, property control, and operations and…

  11. 41 CFR 102-34.335 - How do I submit information to the General Services Administration (GSA) for the Federal Fleet...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... information to the General Services Administration (GSA) for the Federal Fleet Report (FFR)? 102-34.335... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 34-MOTOR VEHICLE MANAGEMENT Federal Fleet Report... Fleet Report (FFR)? (a) Annually, agencies must submit to GSA the information needed to produce the...

  12. Minimum Standards for Police Services. A Report of the Police Standards Committee to the Governor's Commission on Law Enforcement and the Administration of Justice.

    ERIC Educational Resources Information Center

    Governor's Commission on Law Enforcement and the Administration of Justice, Cockeysville, MD.

    The publication enumerates the minimum standards for police services in Maryland which were developed by the Police Standards Committee of the Maryland Governor's Commission on Law Enforcement and the Administration of Justice. They are the result of intensive study after a series of public hearings held throughout the State at which testimony was…

  13. Oral Bisphenol A (BPA) given to rats at moderate doses is associated with erectile dysfunction, cavernosal lipofibrosis and alterations of global gene transcription.

    PubMed

    Kovanecz, I; Gelfand, R; Masouminia, M; Gharib, S; Segura, D; Vernet, D; Rajfer, J; Li, D K; Kannan, K; Gonzalez-Cadavid, N F

    2014-01-01

    Bisphenol A (BPA), a suspected reproductive biohazard and endocrine disruptor, released from plastics is associated with ED in occupationally exposed workers. However, in rats, despite the induction of hypogonadism, apoptosis of the penile corporal smooth muscle (SM), fat infiltration into the cavernosal tissue and changes in global gene expression with the intraperitoneal administration of high dose BPA, ED was not observed. We investigated whether BPA administered orally rather than intraperitoneally to rats for longer periods and lower doses will lead to ED. Main outcome measures are ED, histological, and biochemical markers in rat penile tissues. In all, 2.5-month-old rats were given drinking water daily without and with BPA at 1 and 0.1 mg kg(-1) per day. Two months later, erectile function was determined by cavernosometry and electrical field stimulation (EFS) and serum levels of testosterone (T), estradiol (E2) and BPA were measured. Penile tissue sections were assayed by Masson (SM/collagen), Oil Red O (fat), terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) (apoptosis), immunohistochemistry for Oct4 (stem cells), and α-SM actin/calponin (SM and myofibroblasts), applying quantitative image analysis. Other markers were assayed by western blotting. DNA microarrays/microRNA (miR) assays defined transcription profiles. Orally administered BPA did not affect body weight, but (1) decreased serum T and E2; (2) reduced the EFS response and increased the drop rate; (3) increased within the corporal tissue the presence of fat, myofibroblasts and apoptosis; (4) lowered the contents of SM and stem cells, but not nerve terminals; and (5) caused alterations in the transcriptional profiles for both mRNA and miRs within the penile shaft. Long-term exposure of rats to oral BPA caused a moderate corporal veno-occlusive dysfunction (CVOD), possibly due to alterations within the corporal tissue that pose gene transcriptional changes related to inflammation

  14. From BPA to its analogues: Is it a safe journey?

    PubMed

    Usman, Afia; Ahmad, Masood

    2016-09-01

    Bisphenol-A (BPA) is one of the most abundant synthetic chemicals in the world due to its uses in plastics. Its widespread exposure vis-a-vis low dose effects led to a reduction in its safety dose and imposition of ban on its use in infant feeding bottles. This restriction paved the way for the gradual market entry of its analogues. However, their structural similarity to BPA has put them under surveillance for endocrine disrupting potential. The application of these analogues is increasing and so are the studies reporting their toxicity. This review highlights the reasons which led to the ban of BPA and also reports the exposure and toxicological data available on its analogues. Hence, this compilation is expected to answer in a better way whether the replacement of BPA by these analogues is safer or more harmful?

  15. From BPA to its analogues: Is it a safe journey?

    PubMed

    Usman, Afia; Ahmad, Masood

    2016-09-01

    Bisphenol-A (BPA) is one of the most abundant synthetic chemicals in the world due to its uses in plastics. Its widespread exposure vis-a-vis low dose effects led to a reduction in its safety dose and imposition of ban on its use in infant feeding bottles. This restriction paved the way for the gradual market entry of its analogues. However, their structural similarity to BPA has put them under surveillance for endocrine disrupting potential. The application of these analogues is increasing and so are the studies reporting their toxicity. This review highlights the reasons which led to the ban of BPA and also reports the exposure and toxicological data available on its analogues. Hence, this compilation is expected to answer in a better way whether the replacement of BPA by these analogues is safer or more harmful? PMID:27262103

  16. Design of Studies for Development of BPA Fish and Wildlife Mitigation Accounting Policy Phase II, Volume I, 1985-1988 Summary Report.

    SciTech Connect

    Kneese, Allen V.

    1988-08-01

    As the mitigation prescribed by the Regional Act proceeds, the incremental costs of corrective measures to lessen the environmental impacts of the hydroelectric system are expected to increase and difficult questions to arise about the costs, effectiveness, and justification of alternative measures and their systemwide implications. It was deemed prudent by the BPA to anticipate this situation by launching a forward-looking research program aimed at providing methodological tools and data suitable for estimating the productivity and cost implications of mitigation alternatives in a timely manner with state-of-the-art accuracy. In this spirit, Resources for the Future (RFF) agreed at the request of the BPA to develop a research program which would provide an analytical system designed to assist the BPA Administrator and other interested and responsible parties in evaluating the ecological and economic aspects of alternative protection, enhancement, and mitigation measures. 12 refs., 4 figs., 1 tab.

  17. 47 CFR 54.715 - Administrative expenses of the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Administrative expenses of the Administrator. 54.715 Section 54.715 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.715 Administrative expenses of the Administrator. (a) The annual administrative expenses...

  18. (10)B-NMR determination of (10)B-BPA, (10)B-BPA-fructose complex and total (10)B in blood for BNCT.

    PubMed

    Yoshino, K; Yabe, T; Hattori, T; Saito, K; Ishikawa, A; Ohki, H

    2014-06-01

    First spontaneous, noninvasive determination method of (10)B-BPA, (10)B-BPA-fructose complex, and total (10)B in blood is described. (10)B-NMR measurement with 100,000 FT accumulation enables us to obtain the result within 100min/sample. The detection limits for the simultaneous analysis were 3ppm, 3ppm and 6ppm for (10)B-BPA, (10)B-BPA-fructose complex and total (10)B respectively in this study. By this method, we can actually discuss behavior of the (10)B-BPA-fructose complex in blood.

  19. The National Oceanic and Atmospheric Administration (NOAA) Climate Services Portal: A New Centralized Resource for Distributed Climate Information

    NASA Astrophysics Data System (ADS)

    Burroughs, J.; Baldwin, R.; Herring, D.; Lott, N.; Boyd, J.; Handel, S.; Niepold, F.; Shea, E.

    2010-09-01

    With the rapid rise in the development of Web technologies and climate services across NOAA, there has been an increasing need for greater collaboration regarding NOAA's online climate services. The drivers include the need to enhance NOAA's Web presence in response to customer requirements, emerging needs for improved decision-making capabilities across all sectors of society facing impacts from climate variability and change, and the importance of leveraging climate data and services to support research and public education. To address these needs, NOAA (during fiscal year 2009) embarked upon an ambitious program to develop a NOAA Climate Services Portal (NCS Portal). Four NOAA offices are leading the effort: 1) the NOAA Climate Program Office (CPO), 2) the National Ocean Service's Coastal Services Center (CSC), 3) the National Weather Service's Climate Prediction Center (CPC), and 4) the National Environmental Satellite, Data, and Information Service's (NESDIS) National Climatic Data Center (NCDC). Other offices and programs are also contributing in many ways to the effort. A prototype NCS Portal is being placed online for public access in January 2010, http://www.climate.gov. This website only scratches the surface of the many climate services across NOAA, but this effort, via direct user engagement, will gradually expand the scope and breadth of the NCS Portal to greatly enhance the accessibility and usefulness of NOAA's climate data and services.

  20. Discrepancies between survey and administrative data on the use of mental health services in the general population: findings from a study conducted in Québec

    PubMed Central

    2011-01-01

    Background Population surveys and health services registers are the main source of data for the management of public health. Yet, the validity of survey data on the use of mental health services has been questioned repeatedly due to the sensitive nature of mental illness and to the risk of recall bias. The main objectives of this study were to compare data on the use of mental health services from a large scale population survey and a national health services register and to identify the factors associated with the discrepancies observed between these two sources of data. Methods This study was based on the individual linkage of data from the cycle 1.2 of the Canadian Community Health Survey (CCHS-1.2) and from the health services register of the Régie de l'assurance maladie du Québec (RAMQ). The RAMQ is the governmental agency managing the Quebec national health insurance program. The analyses mostly focused on the 637 Quebecer respondents who were recorded as users of mental health services in the RAMQ and who were self-reported users or non users of these services in the CCHS-1.2. Results Roughly 75%, of those recorded as users of mental health services users in the RAMQ's register did not report using mental health services in the CCHS-1.2. The odds of disagreement between survey and administrative data were higher in seniors, individuals with a lower level of education, legal or de facto spouses and mothers of young children. They were lower in individuals with a psychiatric disorder and in frequent and more recent users of mental health services according to the RAMQ's register. Conclusions These findings support the hypotheses that social desirability and recall bias are likely to affect the self-reported use of mental health services in a population survey. They stress the need to refine the investigation of mental health services in population surveys and to combine survey and administrative data, whenever possible, to obtain an optimal estimation of the

  1. 41 CFR 105-68.630 - May the General Services Administration impute conduct of one person to another?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false May the General Services... Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES... that organization, or with the organization's knowledge, approval or acquiescence. The...

  2. 41 CFR 105-68.630 - May the General Services Administration impute conduct of one person to another?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false May the General Services... Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES... that organization, or with the organization's knowledge, approval or acquiescence. The...

  3. 5 CFR 2430.12 - Administrative Law Judge's decision; contents; service; transfer of case to the Authority...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...; contents; service; transfer of case to the Authority; contents of record in case. 2430.12 Section 2430.12... Judge's decision; contents; service; transfer of case to the Authority; contents of record in case. (a..., and the record of the unfair labor practice proceeding upon which the application is based....

  4. 20 CFR 410.686b - Fee for services performed for an individual before the Social Security Administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969... person or in writing; (ii) There was a death or serious illness in the individual's family;...

  5. 19 CFR 201.207 - Administrative offset against amounts payable from Civil Service Retirement and Disability Fund

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.207 Administrative... Office of Personnel Management; and (3) The Commission has complied with the requirements of 31 CFR...

  6. 19 CFR 201.207 - Administrative offset against amounts payable from Civil Service Retirement and Disability Fund

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.207 Administrative... Office of Personnel Management; and (3) The Commission has complied with the requirements of 31 CFR...

  7. Bonneville Power Administration Wildlife Mitigation Program : Draft Environmental Impact Statement.

    SciTech Connect

    United States. Bonneville Power Administration.

    1996-08-01

    Bonneville Power Administration (BPA) is responsible for mitigating the loss of wildlife habitat caused by the development of the Federal Columbia River Power System. BPA accomplishes this mitigation by funding projects consistent with those recommended by the Northwest Power Planning Council (Council). The projects are submitted to the Council from Indian Tribes, state agencies, property owners, private conservation groups, and other Federal agencies. Future wildlife mitigation actions with potential environmental impacts are expected to include land acquisition and management, water rights acquisition and management, habitat restoration and enhancement, installation of watering devices, riparian fencing, and similar wildlife conservation actions. BPA needs to ensure that individual wildlife mitigation projects are planned and managed with appropriate consistency across projects, jurisdictions, and ecosystems, as well as across time. BPA proposes to standardize the planning and implementation of individual wildlife mitigation projects funded by BPA. Alternative 1 is the No Action alternative. Five standardizing alternatives are identified to represent the range of possible strategies, goals, and procedural requirements reasonably applicable to BPA-funded projects under a standardized approach to project planning and implementation. All action alternatives are based on a single project planning process designed to resolve site-specific issues in an ecosystem context and to adapt to changing conditions and information.

  8. Medicaid program; payments for services furnished by certain primary care physicians and charges for vaccine administration under the Vaccines for Children program. Final rule.

    PubMed

    2012-11-01

    This final rule implements Medicaid payment for primary care services furnished by certain physicians in calendar years (CYs) 2013 and 2014 at rates not less than the Medicare rates in effect in those CYs or, if greater, the payment rates that would be applicable in those CYs using the CY 2009 Medicare physician fee schedule conversion factor. This minimum payment level applies to specified primary care services furnished by a physician with a specialty designation of family medicine, general internal medicine, or pediatric medicine, and also applies to services rendered by these provider types paid by Medicaid managed care plans contracted by states to provide the primary care services. It also provides for 100 percent federal financial participation (FFP) for any increase in payment above the amounts that would be due for these services under the provisions of the approved Medicaid state plan, as of July 1, 2009. In other words, there will not be any additional cost to states for payments above the amount required by the 2009 rate methodology. In this final rule, we specify which services and types of physicians qualify for the minimum payment level in CYs 2013 and 2014, and the method for calculating the payment amount and any increase for which increased federal funding is due. In addition, this final rule will update the interim regional maximum fees that providers may charge for the administration of pediatric vaccines to federally vaccine-eligible children under the Pediatric Immunization Distribution Program, more commonly known as the Vaccines for Children (VFC) program.

  9. Estrogenic chemicals often leach from BPA-free plastic products that are replacements for BPA-containing polycarbonate products

    PubMed Central

    2014-01-01

    Background Xenobiotic chemicals with estrogenic activity (EA), such as bisphenol A (BPA), have been reported to have potential adverse health effects in mammals, including humans, especially in fetal and infant stages. Concerns about safety have caused many manufacturers to use alternatives to polycarbonate (PC) resins to make hard and clear, reusable, plastic products that do not leach BPA. However, no study has focused on whether such BPA-free PC-replacement products, chosen for their perceived higher safety, especially for babies, also release other chemicals that have EA. Methods We used two, well-established, mammalian cell-based, assays (MCF-7 and BG1Luc) to assess the EA of chemicals that leached into over 1000 saline or ethanol extracts of 50 unstressed or stressed (autoclaving, microwaving, and UV radiation) BPA-free PC-replacement products. An EA antagonist, ICI 182,780, was used to confirm that agonist activity in leachates was due to chemicals that activated the mammalian estrogen receptor. Results Many unstressed and stressed, PC-replacement-products made from acrylic, polystyrene, polyethersulfone, and Tritan™ resins leached chemicals with EA, including products made for use by babies. Exposure to various forms of UV radiation often increased the leaching of chemicals with EA. In contrast, some BPA-free PC-replacement products made from glycol-modified polyethylene terephthalate or cyclic olefin polymer or co-polymer resins did not release chemicals with detectable EA under any conditions tested. Conclusions This hazard assessment survey showed that many BPA-free PC- replacement products still leached chemicals having significant levels of EA, as did BPA-containing PC counterparts they were meant to replace. That is, BPA-free did not mean EA-free. However, this study also showed that some PC-replacement products did not leach chemicals having significant levels of EA. That is, EA-free PC-replacement products could be made in commercial quantities at

  10. Environmental Effects of BPA: Focus on Aquatic Species.

    PubMed

    Canesi, Laura; Fabbri, Elena

    2015-01-01

    Research on bisphenol A (BPA) as an environmental contaminant has now major regulatory implications toward the ecosystem health, and hence it is incumbent on scientists to do their research to the highest standards possible, in order that the most appropriate decisions are made to mitigate the impacts to aquatic wildlife. However, the contribution given so far appears rather fragmented. The present overview aims to collect available information on the effects of BPA on aquatic vertebrates and invertebrates to provide a general scenario and to suggest future developments toward more comprehensive approaches useful for aquatic species protection. PMID:26674307

  11. Pharmacokinetics of BPA in Gliomas with Ultrasound Induced Blood-Brain Barrier Disruption as Measured by Microdialysis

    PubMed Central

    Yang, Feng-Yi; Lin, Yi-Li; Chou, Fong-In; Lin, Yu-Chuan; Hsueh Liu, Yen-Wan; Chang, Lun-Wei; Hsieh, Yu-Ling

    2014-01-01

    The blood-brain barrier (BBB) can be transiently disrupted by focused ultrasound (FUS) in the presence of microbubbles for targeted drug delivery. Previous studies have illustrated the pharmacokinetics of drug delivery across the BBB after sonication using indirect visualization techniques. In this study, we investigated the in vivo extracellular kinetics of boronophenylalanine-fructose (BPA-f) in glioma-bearing rats with FUS-induced BBB disruption by microdialysis. After simultaneous intravenous administration of BPA and FUS exposure, the boron concentration in the treated brains was quantified by inductively coupled plasma mass spectroscopy. With FUS, the mean peak concentration of BPA-f in the glioma dialysate was 3.6 times greater than without FUS, and the area under the concentration-time curve was 2.1 times greater. This study demonstrates that intracerebral microdialysis can be used to assess local BBB transport profiles of drugs in a sonicated site. Applying microdialysis to the study of metabolism and pharmacokinetics is useful for obtaining selective information within a specific brain site after FUS-induced BBB disruption. PMID:24936788

  12. Perceptions of Educational Administration Pre-Service Training by Former Illinois Superintendents Currently Serving as University Professors

    ERIC Educational Resources Information Center

    Kaufman, Douglas R.

    2013-01-01

    The 1983 publication of "A Nation at Risk" was the start of the latest chapter in the long history and development of the public school superintendent. "A Nation at Risk" brought new pressure and awareness on university programs that train school administrators coupled with suggestions on how to improve their effectiveness.…

  13. Serving English as a Second Language Communities: A Literary Review and an In-Service Plan To Assist Administrators.

    ERIC Educational Resources Information Center

    Westendorf, David; Karr-Kidwell, PJ

    This paper presents a literature review and describes an inservice plan for aspiring and current elementary administrators in schools serving English-as-a-Second-Language (ESL) communities. The literature review examines habits and guidelines for effective leaders to use in educational settings, discusses laws regarding bilingual/ESL education,…

  14. Brief Report: Effects of an Administrative Supervisory Protocol on Preparation of Behavior Support Plans at a Child Service Setting

    ERIC Educational Resources Information Center

    Garrity, Meredith L.; Luiselli, James K.

    2005-01-01

    We evaluated a supervisory protocol that targeted preparation of behavior support plans by administrative staff at a school for children with developmental disabilities. Using a multiple baseline design, the protocol was applied sequentially to three components of behavior support plan preparation. Intervention procedures included goal…

  15. Final priorities; Rehabilitation Services Administration--Capacity Building Program for Traditionally Underserved Populations--vocational rehabilitation training institute for the preparation of personnel in American Indian Vocation Rehabilitation Services projects. Final priorities.

    PubMed

    2014-08-14

    The Assistant Secretary for Special Education and Rehabilitative Services announces two priorities under the Capacity Building Program for Traditionally Underserved Populations administered by the Rehabilitation Services Administration (RSA). The Assistant Secretary may use one or more of these priorities for competitions in fiscal year (FY) 2014 and later years. Priority 1 establishes a new vocational rehabilitation (VR) training institute for the preparation of personnel in American Indian Vocational Rehabilitation Services (AIVRS) projects (the Institute). Priority 2 requires a partnership between a four-year institution of higher education (IHE) and a two-year community college or tribal college. This partnership is designed to successfully implement the VR training Institute established in Priority 1. In addition, the partnership agreement required under Priority 2 provides a brief description of how the partnership will be managed, the partners' roles and responsibilities and a strategy for sustaining the partnership after the Federal investment ends.

  16. Evidence that bisphenol A (BPA) can be accurately measured without contamination in human serum and urine, and that BPA causes numerous hazards from multiple routes of exposure.

    PubMed

    vom Saal, Frederick S; Welshons, Wade V

    2014-12-01

    There is extensive evidence that bisphenol A (BPA) is related to a wide range of adverse health effects based on both human and experimental animal studies. However, a number of regulatory agencies have ignored all hazard findings. Reports of high levels of unconjugated (bioactive) serum BPA in dozens of human biomonitoring studies have also been rejected based on the prediction that the findings are due to assay contamination and that virtually all ingested BPA is rapidly converted to inactive metabolites. NIH and industry-sponsored round robin studies have demonstrated that serum BPA can be accurately assayed without contamination, while the FDA lab has acknowledged uncontrolled assay contamination. In reviewing the published BPA biomonitoring data, we find that assay contamination is, in fact, well controlled in most labs, and cannot be used as the basis for discounting evidence that significant and virtually continuous exposure to BPA must be occurring from multiple sources.

  17. Evidence that bisphenol A (BPA) can be accurately measured without contamination in human serum and urine, and that BPA causes numerous hazards from multiple routes of exposure

    PubMed Central

    vom Saal, Frederick S.; Welshons, Wade V.

    2016-01-01

    There is extensive evidence that bisphenol A (BPA) is related to a wide range of adverse health effects based on both human and experimental animal studies. However, a number of regulatory agencies have ignored all hazard findings. Reports of high levels of unconjugated (bioactive) serum BPA in dozens of human biomonitoring studies have also been rejected based on the prediction that the findings are due to assay contamination and that virtually all ingested BPA is rapidly converted to inactive metabolites. NIH and industry-sponsored round robin studies have demonstrated that serum BPA can be accurately assayed without contamination, while the FDA lab has acknowledged uncontrolled assay contamination. In reviewing the published BPA biomonitoring data, we find that assay contamination is, in fact, well controlled in most labs, and cannot be used as the basis for discounting evidence that significant and virtually continuous exposure to BPA must be occurring from multiple sources. PMID:25304273

  18. Factors associated with Institutional delivery service utilization among mothers in Bahir Dar City administration, Amhara region: a community based cross sectional study

    PubMed Central

    2014-01-01

    Background High maternal mortality is a continued challenge for the achievement of the fifth millennium development goal in Sub-Saharan African countries including Ethiopia. Although institutional delivery service utilization ensures safe birth and a key to reduce maternal mortality, interventions at the community and/or institutions were unsatisfactorily reduced maternal mortality. Institutional delivery service utilization is affected by the interaction of personal, socio-cultural, behavioral and institutional factors. Therefore this study was designed to assess factors associated with institutional delivery service use among mothers in Bahir Dar city administration. Methods A community based cross sectional study was conducted in Bahir Dar City administration Northwest of Addis Ababa, Ethiopia. Four hundred eighty four mothers were included in the study. Data were collected by trained female data collectors. Descriptive statistics, binary and multivariable logistic regression analyses were computed. Statistical significance was considered at p < 0.05 and the strength of statistical association was assessed by odds ratios (OR) with 95% confidence intervals. Result In this study, 78.8% of women gave birth to their current child at health institution. The multivariable logistic regression showed that, attending primary education (AOR = 4.7[95% CI:1.3-16.7], secondary education (AOR = 3.5[95% CI:1.1-10.7]), age at first marriage; first time marriage at 15–19 years (AOR = 5.4[95% CI:2.0-15.0]) and first time marriage at 20–24 years (AOR = 5.0[95% CI:1.5-16.8] and gestational age at first ANC visit (first trimester) (AOR = 5.3[1.3-22.2]) and second trimester (AOR = 2.8[95% CI:0.7-11.]) were independent factors affecting institutional delivery service utilization. Conclusion In this study, institutional delivery service utilization is optimal, urban mothers were more likely to practice institutional delivery. This study indicated that

  19. [PUBLIC ADMINISTRATION OF PERSONNEL POLICY IN REFORMING OF UKRAINIAN HEALTH CARE SYSTEM USING THE EXAMPLE OF DERMATOVENEREOLOGICAL SERVICE].

    PubMed

    Korolenko, V V; Dykun, O P; Isayenko, R M; Remennyk, O I; Avramenko, T P; Stepanenko, V I; Petrova, K I; Volosovets, O P; Lazoryshynets, V V

    2014-01-01

    The health care system, its modernization and optimization are among the most important functions of the modern Ukrainian state. The main goal of the reforms in the field of healthcare is to improve the health of the population, equal and fair access for all to health services of adequate quality. Important place in the health sector reform belongs to optimizing the structure and function of dermatovenereological service. The aim of this work is to address the issue of human resources management of dermatovenereological services during health sector reform in Ukraine, taking into account the real possibility of disengagement dermatovenereological providing care between providers of primary medical care level (general practitioners) and providers of secondary (specialized) and tertiary (high-specialized) medical care (dermatovenerologists and pediatrician dermatovenerologists), and coordinating interaction between these levels. During research has been found, that the major problems of human resources of dermatovenereological service are insufficient staffing and provision of health-care providers;,growth in the number of health workers of retirement age; sectoral and regional disparity of staffing; the problem of improving the skills of medical personnel; regulatory support personnel policy areas and create incentives for staff motivation; problems of rational use of human resources for health care; problems of personnel training for dermatovenereological service. Currently reforming health sector should primarily serve the needs of the population in a fairly effective medical care at all levels, to ensure that there must be sufficient qualitatively trained and motivated health workers. To achieve this goal directed overall work of the Ministry of Health of Uktaine, the National Academy of Medical Sciences of Ukraine, medical universities, regional health authorities, professional medical associations. Therefore Ukrainian dermatovenereological care, in particular

  20. Services

    ERIC Educational Resources Information Center

    Environmental Science and Technology, 1972

    1972-01-01

    Alphabetical listing of companies which offer analytical sampling and testing services for pollution control and abatement; consultants that also manufacture and distribute products. List of book publishers included. (LK)

  1. Identifying Distinct Geographic Health Service Environments in British Columbia, Canada: Cluster Analysis of Population-Based Administrative Data.

    PubMed

    Lavergne, M Ruth

    2016-08-01

    Definitions of "urban" and "rural" developed for general purposes may not reflect the organization and delivery of healthcare. This research used cluster analysis to group Local Health Areas based on the distribution of healthcare spending across service categories. Though total spending was similar, the metropolitan areas of Vancouver and Victoria were identified as distinct from non-metropolitan and remote communities, based on the distribution of healthcare spending alone. Non-metropolitan communities with large community hospitals and greater physician supply were further distinguished from those with fewer healthcare resources. This approach may be useful to other researchers and service planners. PMID:27585025

  2. Identifying Distinct Geographic Health Service Environments in British Columbia, Canada: Cluster Analysis of Population-Based Administrative Data.

    PubMed

    Lavergne, M Ruth

    2016-08-01

    Definitions of "urban" and "rural" developed for general purposes may not reflect the organization and delivery of healthcare. This research used cluster analysis to group Local Health Areas based on the distribution of healthcare spending across service categories. Though total spending was similar, the metropolitan areas of Vancouver and Victoria were identified as distinct from non-metropolitan and remote communities, based on the distribution of healthcare spending alone. Non-metropolitan communities with large community hospitals and greater physician supply were further distinguished from those with fewer healthcare resources. This approach may be useful to other researchers and service planners.

  3. The Department of Veterans Health Administration Office of Nursing Service, "transforming nursing in a national healthcare system: an example of transformation in action".

    PubMed

    Wertenberger, Sydney; Chapman, Kathleen M; Wright-Brown, Salena

    2011-01-01

    The Department of Veterans Health Administration Office of Nursing Service has embarked on a multiyear transformational process, an example of which is the development of an organization-wide nursing handbook. The development of this handbook offered the opportunity to improve collaboration, redefine expectations and behavior, as well as prepare for the future of Nursing within the Veterans Health Administration. The lessons learned from this process have revolved around the themes of leadership skills for managing high-level change often in a virtual environment; constant collaboration; that the practice of nursing will continue to evolve on the basis of new evidence, technology, customer expectations, and resources; and that the process to accomplish this goal is powerful.

  4. The Snapshot Survey Service: A Web Site for Assessing Teachers' and Administrators' Technology Activities, Beliefs, and Needs.

    ERIC Educational Resources Information Center

    Norris, Cathleen; Soloway, Elliot

    This paper documents the authors' efforts at constructing, deploying, and analyzing Snapshot Surveys in a range of educational settings. The Snapshot Survey Service is an Internet-based technology that enables educators at the local, state, and even national level to survey, quickly and at low-cost, other educators on issues that are particularly…

  5. Health Administrator Perspectives on Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Prevention and Services at Historically Black Colleges and Universities

    ERIC Educational Resources Information Center

    Warren-Jeanpiere, Lari; Jones, Sandra; Sutton, Madeline Y.

    2011-01-01

    Objective: Due to the disproportionate impact of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) among African American young adults, the authors explored (1) number of historically black college and university (HBCU) campuses with existing HIV prevention policies and services and (2) perceived barriers for implementing…

  6. Rehabilitation Training Program and Special Capacity Building Program, 1997-1998: Catalog of Projects under the Rehabilitation Services Administration.

    ERIC Educational Resources Information Center

    Office of Special Education and Rehabilitative Services (ED), Washington, DC.

    This directory lists programs funded by rehabilitation training grants funded under the Rehabilitation Act of 1973 (Section 304a). These programs are grouped under the following categories: (1) rehabilitation long-term training; (2) experimental and innovative training; (3) state vocational rehabilitation unit in-service training; (4)…

  7. 75 FR 63844 - Health Resources and Services Administration CDC/HRSA Advisory Committee on HIV and STD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... CDC/HRSA Advisory Committee on HIV and STD Prevention and Treatment (CHACHSPT) In accordance with... prevention and control of HIV/AIDS and other STDs; the support of health care services to persons living with HIV/AIDS; and the education of health professionals and the public about HIV/AIDS and other...

  8. Comparability Study of Armed Services Vocational Aptitude Battery Scores from Answer Sheet and Answer Card Administration. Final Report.

    ERIC Educational Resources Information Center

    Valentine, Lonnie D., Jr.; Cowan, Douglas K.

    Armed Services Vocational Aptitude Battery (ASVAB) Form 2 was standardized for Digitek answer sheets. In September 1973, the Digitek scoring facility at Randolph AFB will be inadequate to handle anticipated scoring load. Consequently, ASVAB answer forms have been redesigned for processing via a Hewlett-Packard mark-sense reader from IBM card size…

  9. Food Assistance: Financial Information on WIC Nutrition Services and Administrative Costs. United States General Accounting Office Report to Congressional Committees.

    ERIC Educational Resources Information Center

    Robertson, Robert E.

    The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a federally funded nutrition assistance program administered by the Department of Agriculture's (USDA) Food and Nutrition Service (FNS). Responding to Congressional requests for information regarding program costs, this report provides information on: (1) funding…

  10. Therapeutic Case Advocacy Trainers' Guide: A Format for Training Direct Service Staff and Administrators. Therapeutic Case Advocacy Project.

    ERIC Educational Resources Information Center

    Mason, James L.; Young, Thomas M., III

    This guide assists in establishing a collaborative unit or a task group to deliver services to children and youth with serious emotional disabilities and their families. The guide is not intended to be an exhaustive manual, but does address the primary activities of professionals using interagency collaboration to establish comprehensive systems…

  11. GIS Services, Visualization Products, and Interoperability at the National Oceanic and Atmospheric Administration (NOAA) National Climatic Data Center (NCDC)

    NASA Astrophysics Data System (ADS)

    Baldwin, R.; Ansari, S.; Reid, G.; Lott, N.; Del Greco, S.

    2007-12-01

    The main goal in developing and deploying Geographic Information System (GIS) services at NOAA's National Climatic Data Center (NCDC) is to provide users with simple access to data archives while integrating new and informative climate products. Several systems at NCDC provide a variety of climatic data in GIS formats and/or map viewers. The Online GIS Map Services provide users with data discovery options which flow into detailed product selection maps, which may be queried using standard "region finder" tools or gazetteer (geographical dictionary search) functions. Each tabbed selection offers steps to help users progress through the systems. A series of additional base map layers or data types have been added to provide companion information. New map services include: Severe Weather Data Inventory, Local Climatological Data, Divisional Data, Global Summary of the Day, and Normals/Extremes products. THREDDS Data Server technology is utilized to provide access to gridded multidimensional datasets such as Model, Satellite and Radar. This access allows users to download data as a gridded NetCDF file, which is readable by ArcGIS. In addition, users may subset the data for a specific geographic region, time period, height range or variable prior to download. The NCDC Weather Radar Toolkit (WRT) is a client tool which accesses Weather Surveillance Radar 1988 Doppler (WSR-88D) data locally or remotely from the NCDC archive, NOAA FTP server or any URL or THREDDS Data Server. The WRT Viewer provides tools for custom data overlays, Web Map Service backgrounds, animations and basic filtering. The export of images and movies is provided in multiple formats. The WRT Data Exporter allows for data export in both vector polygon (Shapefile, Well-Known Text) and raster (GeoTIFF, ESRI Grid, VTK, NetCDF, GrADS) formats. As more users become accustom to GIS, questions of better, cheaper, faster access soon follow. Expanding use and availability can best be accomplished through

  12. Removal of bisphenol A (BPA) in a nitrifying system with immobilized biomass.

    PubMed

    Zielińska, Magdalena; Cydzik-Kwiatkowska, Agnieszka; Bernat, Katarzyna; Bułkowska, Katarzyna; Wojnowska-Baryła, Irena

    2014-11-01

    The potential for bisphenol A (BPA) removal by mixed consortia of immobilized microorganisms with high nitrification activity was investigated with BPA concentrations in the influent from 2.5 to 10.0 mg/L. The presence of BPA limited ammonium oxidation; nitrification efficiency decreased from 91.2±1.3% in the control series to 47.4±9.4% when BPA concentration in wastewater was the highest. The efficiency of BPA removal rose from 87.1±5.5% to 92.9±2.9% with increased BPA concentration in the influent. Measurement of oxygen uptake rates by biomass exposed to BPA showed that BPA was mainly removed by heterotrophic bacteria. A strong negative correlation between the BPA removal efficiency and nitrification efficiency indicated the limited contribution of ammonia-oxidizing bacteria (AOB) to BPA biodegradation. Exposure of biomass to BPA changed the quantity and diversity of AOB in the biomass as shown by real-time PCR and denaturing gradient gel electrophoresis.

  13. American Recovery and Reinvestment Act ( ARRA) FEMP Technical Assistance, U.S. General Services Administration - Project 194 U.S. Custom Cargo Inspection Facility, Detroit, MI

    SciTech Connect

    Arends, J.; Sandusky, William F.

    2010-05-31

    This report documents the findings of an on-site audit of the U.S. Customs Cargo Inspection Facility (CIF) in Detroit, Michigan. The federal landlord for this building is the General Services Administration (GSA). The focus of the audit was to identify various no-cost or low-cost energy-efficiency opportunities that, once implemented, would reduce electrical and gas consumption and increase the operational efficiency of the building. This audit also provided an opportunity to identify potential capital cost projects that should be considered in the future to acquire additional energy (electric and gas) and water savings to further increase the operational efficiency of the building.

  14. Removal of bisphenol A (BPA) from water by various nanofiltration (NF) and reverse osmosis (RO) membranes.

    PubMed

    Yüksel, Suna; Kabay, Nalan; Yüksel, Mithat

    2013-12-15

    The removal of an endocrine disrupting compound, bisphenol A (BPA), from model solutions by selected nanofiltration (NF) and reverse osmosis (RO) membranes was studied. The commercially available membranes NF 90, NF 270, XLE BWRO, BW 30 (Dow FilmTech), CE BWRO and AD SWRO (GE Osmonics) were used to compare their performances for BPA removal. The water permeability coefficients, rejection of BPA and permeate flux values were calculated for all membranes used. No significant changes in their BPA removal were observed for all tight polyamide based NF and RO membranes tested except for loose NF 270 membrane. The polyamide based membranes exhibited much better performance than cellulose acetate membrane for BPA removal. Almost a complete rejection (≥ 98%) for BPA was obtained with three polyamide based RO membranes (BW 30, XLE BWRO and AD SWRO). But cellulose acetate based CE BWRO membrane offered a low and variable (10-40%) rejection for BPA.

  15. Removal of bisphenol A (BPA) from water by various nanofiltration (NF) and reverse osmosis (RO) membranes.

    PubMed

    Yüksel, Suna; Kabay, Nalan; Yüksel, Mithat

    2013-12-15

    The removal of an endocrine disrupting compound, bisphenol A (BPA), from model solutions by selected nanofiltration (NF) and reverse osmosis (RO) membranes was studied. The commercially available membranes NF 90, NF 270, XLE BWRO, BW 30 (Dow FilmTech), CE BWRO and AD SWRO (GE Osmonics) were used to compare their performances for BPA removal. The water permeability coefficients, rejection of BPA and permeate flux values were calculated for all membranes used. No significant changes in their BPA removal were observed for all tight polyamide based NF and RO membranes tested except for loose NF 270 membrane. The polyamide based membranes exhibited much better performance than cellulose acetate membrane for BPA removal. Almost a complete rejection (≥ 98%) for BPA was obtained with three polyamide based RO membranes (BW 30, XLE BWRO and AD SWRO). But cellulose acetate based CE BWRO membrane offered a low and variable (10-40%) rejection for BPA. PMID:23731784

  16. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    SciTech Connect

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA's Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  17. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    SciTech Connect

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA`s Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  18. Veterans Administration Databases

    Cancer.gov

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  19. State Regulation of Medication Administration by Unlicensed Assistive Personnel in Residential Care and Adult Day Services Settings.

    PubMed

    Carder, Paula C; O'Keeffe, Janet

    2016-09-01

    Residential care settings and adult day services are two community-based care options used by older adults with chronic health conditions. Most states have regulatory provisions that allow unlicensed assistive personnel (UAP) to administer medications. The current national policy study examined state regulations to identify which states permit UAP to administer medications, as well as staffing and training requirements. Key findings include states lack clear and adequate provisions for nurse oversight of UAP who administer medications, although adult day service regulations provide a greater level of nurse oversight than residential care settings. Specifically, 32 states require residential care to hire a nurse, but only six include provisions regarding nurse availability (e.g., on-call, on-site, number of hours). In contrast, 10 of 20 states that require adult day service programs to hire a nurse provide availability provisions. Nurse oversight of UAP is an important means of assuring quality care and reducing errors; thus, state regulatory agencies might need to strengthen nurse oversight provisions. [Res Gerontol Nurs. 2016; 9(5):209-222.]. PMID:27054368

  20. Bonneville Power Administration, Fish and Wildlife Implementation Plan Draft Environmental Impact Statement

    SciTech Connect

    N /A

    2001-06-22

    Despite the efforts of BPA and other regional entities in the Pacific Northwest, some species of fish and wildlife continue to decline. Reasons for the lack of success include: different groups have different values and priorities, there is no clear scientific answer, and there are conflicting directives and jurisdictions. The absence of a comprehensive and coordinated planning approach has caused inefficiencies in implementation of mitigation and recovery efforts, as well as their funding. On behalf of the Federal Columbia River Power System, BPA funds a large share of the regional efforts. BPA needs a comprehensive and consistent policy to guide the implementation and funding of its fish and wildlife mitigation and recovery efforts. BPA reviewed the many ongoing processes, identified key issues, and developed alternative policy directions based on alternatives developed by existing initiatives in the region. BPA examined five alternative Policy Directions (Natural Focus, Weak Stock Focus, Sustainable Use, Strong Stock Focus, and Commerce Focus) in relationship to continuing the Status Quo, or ''no action'', approach. The EIS evaluates the environmental consequences of BPA's implementation and funding of sample actions that could emerge from any of the policy directions. BPA does not intend to unilaterally select a Policy Direction for the region. Instead, this EIS provides an analysis of the full range of regional alternatives so that a timely funding and implementation strategy may proceed regardless of the alternative policy that ultimately is chosen--whether by design or by default. The BPA Administrator's initial decision, as well as future tiered decisions, will rely on the environmental analysis and the comparison of the alternatives against the purposes for action. The decisions will consider BPA's fish and wildlife responsibilities, as well as the agency's business responsibilities as a Federal Power Marketing Agency and its responsibility to provide

  1. Enantioselective synthesis of L-(-)-4- boronophenylalanine (L-BPA)

    DOEpatents

    Samsel, Edward G.

    1992-01-01

    A method of making substantially pure L-BPA is disclosed. The method includes the steps of reacting 4-bromobenzaldehyde with ethylene glycol to form 4-bromobenzaldehyde ethylene glycol acetal, sequentially reacting 4-bromobenzaldehyde ethyleneglycol acetal with Mg to produce the Grignard reagent and thereafter reacting with tributyl borate and then converting to an acid environment to form 4-boronobenzaldehyde, reacting 4-boronobenzaldehyde with diethanol amine to form 4-boronobenzaldehyde diethanolamine ester, condensing the 4-boronobenzaldehyde diethanolamine ester with 2-phenyl-2-oxazolin-5-one to form an azlactone, reacting the azlactone with an alkali metal hydroxide to form z-.alpha.-benzoylamino-4-boronocinnamic acid, asymmetrically hydrogenating the z-.alpha.-benzoylamino-4-boronocinnamic acid in the presence of a catalyst of a cheltate complex of rhodium (I) with chiral bisphosphines to form L-(+)-N-benzoyl-4-boronophenylalanine, and thereafter acidifying the L-(+)-N-benzoyl-4-boronophenylalanine in an organic medium to produce L-BPA.

  2. Enantioselective synthesis of L-(-)-4- boronophenylalanine (L-BPA)

    DOEpatents

    Samsel, E.G.

    1992-10-20

    A method of making substantially pure L-BPA is disclosed. The method includes the steps of reacting 4-bromobenzaldehyde with ethylene glycol to form 4-bromobenzaldehyde ethylene glycol acetal, sequentially reacting 4-bromobenzaldehyde ethyleneglycol acetal with Mg to produce the Grignard reagent and thereafter reacting with tributyl borate and then converting to an acid environment to form 4-boronobenzaldehyde, reacting 4-boronobenzaldehyde with diethanol amine to form 4-boronobenzaldehyde diethanolamine ester, condensing the 4-boronobenzaldehyde diethanolamine ester with 2-phenyl-2-oxazolin-5-one to form an azlactone, reacting the azlactone with an alkali metal hydroxide to form z-[alpha]-benzoylamino-4boronocinnamic acid, asymmetrically hydrogenating the z-[alpha]-benzoylamino-4-boronocinnamic acid in the presence of a catalyst of a cheltate complex of rhodium (I) with chiral bisphosphines to form L-(+)-N-benzoyl-4-boronophenylalanine, and thereafter acidifying the L-(+)-N-benzoyl-4-boronophenylalanine in an organic medium to produce L-BPA. 3 figs.

  3. 77 FR 26275 - Bonneville Power Administration; Montana-to-Washington Transmission System Upgrade Project EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... Bonneville Power Administration; Montana-to-Washington Transmission System Upgrade Project EIS AGENCY... Sinha, Project Manager, Bonneville Power Administration--TEP-3, P.O. Box 3621, Portland, Oregon 97208... (including wind generators and power marketers) requested the use of BPA's transmission system to...

  4. 7 CFR 201.3 - Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Administration § 201.3 Administrator. The Administrator of the Agricultural Marketing Service...

  5. Substance Abuse and Mental Health Services Administration; mental health and substance abuse emergency response criteria. Interim final rule.

    PubMed

    2001-10-11

    Section 3102 of the Children's Health Act of 2000, Pub. L. 106-310, amends section 501 of the Public Health Service (PHS) Act (42 U.S.C. 290 aa) to add a new subsection (m) entitled "Emergency Response." This newly enacted subsection 501(m) authorizes the Secretary to use up to, but no more than, 2.5% of all amounts appropriated under Title V of the PHS Act, other than those appropriated under Part C, in each fiscal year to make "noncompetitive grants, contracts or cooperative agreements to public entities to enable such entities to address emergency substance abuse or mental health needs in local communities." Because Congress believed the Secretary needed the ability to respond to emergencies, it exempted any grants,contracts, or cooperative agreements authorized under this section from the peer review process otherwise required by section 504 of the PHS Act. See section 501(m)(1) of the PHS Act. Instead, the Secretary is to use an objective review process by establishing objective criteria to review applications for funds under this authority. Pursuant to Public Law 106-310, the Secretary is required to establish, and publish in the Federal Register, criteria for determining when a mental health or substance abuse emergency exists. In this interim final rule, the Secretary sets out these criteria, as well as the intended approach for implementing this new mental health and substance abuse emergency response authority. The Secretary invites public comments on both the criteria and the approach described in this interim final rule.

  6. Canby Area Service Project : Substation and Associated Transmission Line : Environmental Assessment.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp's substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC's Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC's substation can accommodate only about 10 percent of the expected additional electric load. BPA's proposed action is intended to meet SVEC's increasing electric load. BPA proposes to meet SVEC's increasing energy load by tapping into BPA's existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC's Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no environmental impact statement'' is not required.

  7. Canby Area Service Project substation and associated transmission line. Environmental Assessment

    SciTech Connect

    Not Available

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp`s substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC`s Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC`s substation can accommodate only about 10 percent of the expected additional electric load. BPA`s proposed action is intended to meet SVEC`s increasing electric load. BPA proposes to meet SVEC`s increasing energy load by tapping into BPA`s existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC`s Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no ``environmental impact statement`` is not required.

  8. Mitochondrion-mediated apoptosis is involved in reproductive damage caused by BPA in male rats.

    PubMed

    Wang, Peng; Luo, Chunhua; Li, Qianyuan; Chen, Sai; Hu, Yong

    2014-11-01

    Bisphenol A (BPA) is a widely used environmental endocrine disruptor. Many studies have reported that BPA exposure shows reproductive toxicity and causes apoptosis in spermatogenic cells. However, few studies have investigated the relationship between the mitochondrial pathway and BPA-induced apoptosis. This study investigated the role of the mitochondrial pathway in apoptosis induced by BPA, which resulted in compromised male rat spermatogenesis and reproductive damage. Rats were exposed to various BPA concentrations (0, 50, 100, or 200mg of BPA/kg body weight per day), and factors in the mitochondrial signal transduction pathway and the apoptosis indices of spermatogenic cells were measured and sperm characteristics were analyzed. Our data revealed that BPA exposure increased the protein and mRNA levels of cytochrome C, apoptosis-inducing factor, caspase-3/9, and Bax; caspase-3 and caspase-9 activities; and the apoptosis indices of spermatogenic cells. In addition, abnormal structure of mitochondria and decreased protein and gene levels of Bcl-2 were observed following BPA exposure. These results suggest that apoptosis in the mitochondrial pathway mediates compromised reproductive system function caused by BPA exposure.

  9. Developmental programming: interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep.

    PubMed

    Veiga-Lopez, Almudena; Moeller, Jacob; Sreedharan, Rohit; Singer, Kanakadurga; Lumeng, Carey; Ye, Wen; Pease, Anthony; Padmanabhan, Vasantha

    2016-02-01

    Among potential contributors for the increased incidence of metabolic diseases is the developmental exposure to endocrine-disrupting chemicals such as bisphenol A (BPA). BPA is an estrogenic chemical used in a variety of consumer products. Evidence points to interactions of BPA with the prevailing environment. The aim of this study was to assess the effects of prenatal exposure to BPA on postnatal metabolic outcomes, including insulin resistance, adipose tissue distribution, adipocyte morphometry, and expression of inflammatory markers in adipose tissue as well as to assess whether postnatal overfeeding would exacerbate these effects. Findings indicate that prenatal BPA exposure leads to insulin resistance in adulthood in the first breeder cohort (study 1), but not in the second cohort (study 2), which is suggestive of potential differences in genetic susceptibility. BPA exposure induced adipocyte hypertrophy in the visceral fat depot without an accompanying increase in visceral fat mass or increased CD68, a marker of macrophage infiltration, in the subcutaneous fat depot. Cohens effect size analysis found the ratio of visceral to subcutaneous fat depot in the prenatal BPA-treated overfed group to be higher compared with the control-overfed group. Altogether, these results suggest that exposure to BPA during fetal life at levels found in humans can program metabolic outcomes that lead to insulin resistance, a forerunner of type 2 diabetes, with postnatal obesity failing to manifest any interaction with prenatal BPA relative to insulin resistance and adipocyte hypertrophy.

  10. Mineralization of bisphenol A (BPA) by anodic oxidation with boron-doped diamond (BDD) electrode.

    PubMed

    Murugananthan, M; Yoshihara, S; Rakuma, T; Shirakashi, T

    2008-06-15

    Anodic oxidation of bisphenol A (BPA), a representative endocrine disrupting chemical, was carried out using boron-doped diamond (BDD) electrode at galvanostatic mode. The electro-oxidation behavior of BPA at BDD electrode was investigated by means of cyclic voltammetric technique. The extent of degradation and mineralization of BPA were monitored by HPLC and total organic carbon (TOC) value, respectively. The results obtained, indicate that the BPA removal at BDD depends on the applied current density (Iappl), initial concentration of BPA, pH of electrolyte and supporting medium. Galvanostatic electrolysis at BDD anode cause concomitant generation of hydroxyl radical that leads to the BPA destruction. The kinetics for the BPA degradation follows a pseudo-first order reaction with a higher rate constant 12.8x10(-5) s(-1) for higher Iappl value 35.7 mA cm(-2), indicating that the oxidation reaction is limited by Iappl control. Complete mineralization of BPA was achieved regardless of the variables and accordingly the mineralization current efficiency was calculated from the TOC removal measurements. Considering global oxidation process, the effect of supporting electrolytes has been discussed in terms of the electro generated inorganic oxidants. The better performance of BDD anode was proved on a comparative study with Pt and glassy carbon under similar experimental conditions. A possible reaction mechanism for BPA degradation involving three main aromatic intermediates, identified by GC-MS analysis, was proposed.

  11. Developmental programming: interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep.

    PubMed

    Veiga-Lopez, Almudena; Moeller, Jacob; Sreedharan, Rohit; Singer, Kanakadurga; Lumeng, Carey; Ye, Wen; Pease, Anthony; Padmanabhan, Vasantha

    2016-02-01

    Among potential contributors for the increased incidence of metabolic diseases is the developmental exposure to endocrine-disrupting chemicals such as bisphenol A (BPA). BPA is an estrogenic chemical used in a variety of consumer products. Evidence points to interactions of BPA with the prevailing environment. The aim of this study was to assess the effects of prenatal exposure to BPA on postnatal metabolic outcomes, including insulin resistance, adipose tissue distribution, adipocyte morphometry, and expression of inflammatory markers in adipose tissue as well as to assess whether postnatal overfeeding would exacerbate these effects. Findings indicate that prenatal BPA exposure leads to insulin resistance in adulthood in the first breeder cohort (study 1), but not in the second cohort (study 2), which is suggestive of potential differences in genetic susceptibility. BPA exposure induced adipocyte hypertrophy in the visceral fat depot without an accompanying increase in visceral fat mass or increased CD68, a marker of macrophage infiltration, in the subcutaneous fat depot. Cohens effect size analysis found the ratio of visceral to subcutaneous fat depot in the prenatal BPA-treated overfed group to be higher compared with the control-overfed group. Altogether, these results suggest that exposure to BPA during fetal life at levels found in humans can program metabolic outcomes that lead to insulin resistance, a forerunner of type 2 diabetes, with postnatal obesity failing to manifest any interaction with prenatal BPA relative to insulin resistance and adipocyte hypertrophy. PMID:26646100

  12. 20 CFR 652.8 - Administrative provisions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FUNCTIONING OF STATE EMPLOYMENT SERVICES Employment Service Operations § 652.8 Administrative provisions. (a... consistent with the provisions of the Act, describing services offered by employment security agencies, job... government lawfully charged with administration of unemployment compensation laws, employment...

  13. BPA/Puget Power Northwest Washington Transmission Project Final Environmental Impact Statement.

    SciTech Connect

    United States. Bonneville Power Administration.

    1995-08-01

    Bonneville Power Administration (BPA) and Puget Sound Power & Light Company (Puget Power) propose to upgrade the existing high-voltage transmission system in the Whatcom and Skagit counties area between the towns of Custer and Sedro Woolley, including some areas within the City of Bellingham, starting in 1995. A Draft Environmental Impact Statement (DEIS) for the project was issued in November 1993, followed by a 45-day public comment period. Public response to the DEIS included the identification of several new transmission route alternatives in the Lake Whatcom area. BPA issued a Supplemental DEIS in April 1995 to provide a second public review-and-comment period. Rebuilding an existing 230-kV line to a double-circuit 230-kV transmission line was identified in the Supplemental DEIS as the Proposed Action. The Supplemental DEIS also examined in detail a North Shore Road alternative which was proposed by some members of the public. Public comments on the EIS were listed and responded to in the Supplemental DEIS. In May 1995, a second set of open houses and public meetings was held to review the Supplemental DEIS. Electromagnetic field (EMF) effects raised as an issue in the DEIS continued to be an issue of public concern in the meetings. The EIS has identified impacts that would generally be classified as low to moderate and localized. Effects on soils and water resources in sensitive areas (e.g., near Lake Whatcom) would be low to moderate; there would be little change in magnetic fields; noise levels would remain at existing levels; and land use and property value impacts would be minimal. Threatened and endangered species would not be adversely affected, and all proposed actions in wetlands would be covered by a Corps of Engineers Nationwide Permit. Visual and socioeconomic would be low to moderate. There would be no effect on cultural resources.

  14. A CLAS act? Community-based organizations, health service decentralization and primary care development in Peru. Local Committees for Health Administration.

    PubMed

    Iwami, Michiyo; Petchey, Roland

    2002-12-01

    In 1994 Peru embarked on a programme of health service reform, which combined primary care development and community participation through Local Committees for Health Administration (CLAS). They are responsible for carrying out local health needs assessments and identifying unmet health needs through regular household surveys. These enable them to determine local health provision and tailor services to local requirements. CLAS build on grassroots self-help circles that developed during the economic and political crises of the 1980s, and in which women have been prominent. However, they function under a 3 year contract with the Ministry of Health and within a framework of centrally determined guidelines and regulations. These reforms were implemented in the context of neo-liberal economic policies, which stressed financial deregulation and fiscal and monetary restraint, and were aimed at reducing foreign indebtedness and inflation. We evaluate the achievements of the CLAS and analyse the relationship between health and economic policy in Peru, with the aid of two contrasting models of the role of the state - 'agency' and 'stewardship'. We argue that Peru's experience holds valuable lessons for other countries seeking to foster community involvement. These include the need for community capacity building and partnership between community organizations and state (and other civil) agencies. PMID:12546199

  15. 5 CFR 831.301 - Military service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Administration (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed... (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed before...

  16. 5 CFR 831.301 - Military service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Administration (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed... (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed before...

  17. 5 CFR 831.301 - Military service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Administration (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed... (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed before...

  18. 5 CFR 831.301 - Military service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Administration (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed... (formerly Coast and Geodetic Survey and Environmental Science Services Administration), performed before...

  19. Annual Review of BPA-Funded Projects in Natural and Artificial Propagation of Salmonids, March 27-29, 1985, Holiday Inn Airport, Portland, Oregon.

    SciTech Connect

    United States. Bonneville Power Administration.

    1985-04-01

    The Fish and Wildlife Division of Bonneville Power Administration (BPA) hosted a meeting for contractors to present the results of fiscal year 1984 research conducted to implement the Northwest Power Planning Council's Fish and Wildlife Program. The meeting focused on those projects specifically related to natural and artificial propagation of salmonids. The presentations were held at the Holiday Inn Airport in Portland, Oregon, on March 27-29, 1985. This document contains abstracts of the presentations from that meeting. Section 1 contains abstracts on artificial propagation, fish health, and downstream migration, and Section 2 contains abstracts on natural propagation and habitat improvement. The abstracts are indexed by BPA Project Number and by Fish and Wildlife Program Measure. The registered attendees at the meeting are listed alphabetically in Appendix A and by affiliation in Appendix B.

  20. Developmental exposure to bisphenol A (BPA) alters sexual differentiation in painted turtles (Chrysemys picta)

    USGS Publications Warehouse

    Jandegian, Caitlin M.; Deem, Sharon L.; Bhandari, Ramji K.; Holliday, Casey M.; Nicks, Diane; Rosenfeld, Cheryl S.; Selcer, Kyle; Tillitt, Donald E.; vom Saal, Fredrick S.; Velez, Vanessa; Yang, Ying; Holliday, Dawn K.

    2015-01-01

    Environmental chemicals can disrupt endocrine signaling and adversely impact sexual differentiation in wildlife. Bisphenol A (BPA) is an estrogenic chemical commonly found in a variety of habitats. In this study, we used painted turtles (Chrysemys picta), which have temperature-dependent sex determination (TSD), as an animal model for ontogenetic endocrine disruption by BPA. We hypothesized that BPA would override TSD and disrupt sexual development. We incubated farm-raised turtle eggs at the male-producing temperature (26 °C), randomly assigned individuals to treatment groups: control, vehicle control, 17β-estradiol (E2, 20 ng/g-egg) or 0.01, 1.0, 100 μg BPA/g-egg and harvested tissues at hatch. Typical female gonads were present in 89% of the E2-treated “males”, but in none of the control males (n = 35). Gonads of BPA-exposed turtles had varying amounts of ovarian-like cortical (OLC) tissue and disorganized testicular tubules in the medulla. Although the percentage of males with OLCs increased with BPA dose (BPA-low = 30%, BPA-medium = 33%, BPA-high = 39%), this difference was not significant (p = 0.85). In all three BPA treatments, SOX9 patterns revealed disorganized medullary testicular tubules and β-catenin expression in a thickened cortex. Liver vitellogenin, a female-specific liver protein commonly used as an exposure biomarker, was not induced by any of the treatments. Notably, these results suggest that developmental exposure to BPA disrupts sexual differentiation in painted turtles. Further examination is necessary to determine the underlying mechanisms of sex reversal in reptiles and how these translate to EDC exposure in wild populations.

  1. Developmental exposure to bisphenol A (BPA) alters sexual differentiation in painted turtles (Chrysemys picta).

    PubMed

    Jandegian, Caitlin M; Deem, Sharon L; Bhandari, Ramji K; Holliday, Casey M; Nicks, Diane; Rosenfeld, Cheryl S; Selcer, Kyle W; Tillitt, Donald E; Vom Saal, Frederick S; Vélez-Rivera, Vanessa; Yang, Ying; Holliday, Dawn K

    2015-05-15

    Environmental chemicals can disrupt endocrine signaling and adversely impact sexual differentiation in wildlife. Bisphenol A (BPA) is an estrogenic chemical commonly found in a variety of habitats. In this study, we used painted turtles (Chrysemys picta), which have temperature-dependent sex determination (TSD), as an animal model for ontogenetic endocrine disruption by BPA. We hypothesized that BPA would override TSD and disrupt sexual development. We incubated farm-raised turtle eggs at the male-producing temperature (26°C), randomly assigned individuals to treatment groups: control, vehicle control, 17β-estradiol (E2, 20ng/g-egg) or 0.01, 1.0, 100μgBPA/g-egg and harvested tissues at hatch. Typical female gonads were present in 89% of the E2-treated "males", but in none of the control males (n=35). Gonads of BPA-exposed turtles had varying amounts of ovarian-like cortical (OLC) tissue and disorganized testicular tubules in the medulla. Although the percentage of males with OLCs increased with BPA dose (BPA-low=30%, BPA-medium=33%, BPA-high=39%), this difference was not significant (p=0.85). In all three BPA treatments, SOX9 patterns revealed disorganized medullary testicular tubules and β-catenin expression in a thickened cortex. Liver vitellogenin, a female-specific liver protein commonly used as an exposure biomarker, was not induced by any of the treatments. Notably, these results suggest that developmental exposure to BPA disrupts sexual differentiation in painted turtles. Further examination is necessary to determine the underlying mechanisms of sex reversal in reptiles and how these translate to EDC exposure in wild populations. PMID:25863134

  2. Developmental exposure to bisphenol A (BPA) alters sexual differentiation in painted turtles (Chrysemys picta).

    PubMed

    Jandegian, Caitlin M; Deem, Sharon L; Bhandari, Ramji K; Holliday, Casey M; Nicks, Diane; Rosenfeld, Cheryl S; Selcer, Kyle W; Tillitt, Donald E; Vom Saal, Frederick S; Vélez-Rivera, Vanessa; Yang, Ying; Holliday, Dawn K

    2015-05-15

    Environmental chemicals can disrupt endocrine signaling and adversely impact sexual differentiation in wildlife. Bisphenol A (BPA) is an estrogenic chemical commonly found in a variety of habitats. In this study, we used painted turtles (Chrysemys picta), which have temperature-dependent sex determination (TSD), as an animal model for ontogenetic endocrine disruption by BPA. We hypothesized that BPA would override TSD and disrupt sexual development. We incubated farm-raised turtle eggs at the male-producing temperature (26°C), randomly assigned individuals to treatment groups: control, vehicle control, 17β-estradiol (E2, 20ng/g-egg) or 0.01, 1.0, 100μgBPA/g-egg and harvested tissues at hatch. Typical female gonads were present in 89% of the E2-treated "males", but in none of the control males (n=35). Gonads of BPA-exposed turtles had varying amounts of ovarian-like cortical (OLC) tissue and disorganized testicular tubules in the medulla. Although the percentage of males with OLCs increased with BPA dose (BPA-low=30%, BPA-medium=33%, BPA-high=39%), this difference was not significant (p=0.85). In all three BPA treatments, SOX9 patterns revealed disorganized medullary testicular tubules and β-catenin expression in a thickened cortex. Liver vitellogenin, a female-specific liver protein commonly used as an exposure biomarker, was not induced by any of the treatments. Notably, these results suggest that developmental exposure to BPA disrupts sexual differentiation in painted turtles. Further examination is necessary to determine the underlying mechanisms of sex reversal in reptiles and how these translate to EDC exposure in wild populations.

  3. Bonneville Power Administration 1993 Annual Report.

    SciTech Connect

    United States. Bonneville Power Administration.

    1994-01-01

    For the first time in a decade, Bonneville had to propose a double digit rate increase in 1993. Many of the causes were beyond our control, but self-examination and painful budget cuts put the focus squarely where it should be -- on the changes needed for BPA to compete in an increasingly market-driven business environment. As deregulation and change sweep the electricity industry, BPA has launched a major Competitiveness Project. It`s clear that we can, and will, cut costs and make ourselves more efficient. We can shape our products and services to better reflect what customers want and are willing to pay for. And more than ever we will measure and reward output -- results -- more than process. BPA today is the Northwest`s low-cost supplier of electricity and transmission services. To stay that way, we must adopt a more business-like model. The move does not signal a rejection of our role as a federal agency. In fact, close attention to sound business principles is the only way to strengthen our commitment to fish and wildlife, environment, and other community values.

  4. The role of Pten/Akt signaling pathway involved in BPA-induced apoptosis of rat Sertoli cells.

    PubMed

    Wang, Chengmin; Fu, Wenjuan; Quan, Chao; Yan, Maosheng; Liu, Changjiang; Qi, Suqin; Yang, Kedi

    2015-07-01

    Bisphenol-A (BPA), one of endocrine-disrupting chemicals, is a male reproductive toxicant. Previous studies have revealed the direct cytotoxicity of BPA in many cultured cells, such as mitotic aneuploidy in embryonic cells and somatic cells, and apoptosis in neurons and testicular Sertoli cells. To understand the action of BPA and assess its risk, the Pten/Akt pathway was investigated in cultured Sertoli cells to elucidate the mechanism of the reproductive effects of BPA. The results showed that over 50 μM BPA treatment could decrease the viability of Sertoli cells and cause more apoptosis. In addition, BPA could induce the increase in mRNA levels of Pten and Akt. The protein level of Pten was increased; however, the protein levels of phospho-Akt and procaspase-3 were decreased after BPA exposure. Taken together, observed results suggested that the Pten/Akt pathway might be involved in the apoptotic effects of BPA on Sertoli cells.

  5. Bisphenol Analogues Other Than BPA: Environmental Occurrence, Human Exposure, and Toxicity-A Review.

    PubMed

    Chen, Da; Kannan, Kurunthachalam; Tan, Hongli; Zheng, Zhengui; Feng, Yong-Lai; Wu, Yan; Widelka, Margaret

    2016-06-01

    Numerous studies have investigated the environmental occurrence, human exposure, and toxicity of bisphenol A (BPA). Following stringent regulations on the production and usage of BPA, several bisphenol analogues have been produced as a replacement for BPA in various applications. The present review outlines the current state of knowledge on the occurrence of bisphenol analogues (other than BPA) in the environment, consumer products and foodstuffs, human exposure and biomonitoring, and toxicity. Whereas BPA was still the major bisphenol analogue found in most environmental monitoring studies, BPF and BPS were also frequently detected. Elevated concentrations of BPAF, BPF, and BPS (i.e., similar to or greater than that of BPA) have been reported in the abiotic environment and human urine from some regions. Many analogues exhibit endocrine disrupting effects, cytotoxicity, genotoxicity, reproductive toxicity, dioxin-like effects, and neurotoxicity in laboratory studies. BPAF, BPB, BPF, and BPS have been shown to exhibit estrogenic and/or antiandrogenic activities similar to or even greater than that of BPA. Knowledge gaps and research needs have been identified, which include the elucidation of environmental occurrences, persistence, and fate of bisphenol analogues (other than BPA), sources and pathways for human exposure, effects on reproductive systems and the mammary gland, mechanisms of toxicity from coexposure to multiple analogues, metabolic pathways and products, and the impact of metabolic modification on toxicity. PMID:27143250

  6. Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells

    PubMed Central

    Bontempo, Paola; Mita, Luigi; Doto, Antonella; Miceli, Marco; Nebbioso, Angela; Lepore, Ilaria; Franci, GianLuigi; Menafra, Roberta; Carafa, Vincenzo; Conte, Mariarosaria; De Bellis, Floriana; Manzo, Fabio; Di Cerbo, Vincenzo; Benedetti, Rosaria; D'Amato, Loredana; Marino, Maria; Bolli, Alessandro; Del Pozzo, Giovanna; Diano, Nadia; Portaccio, Marianna; Mita, Gustavo D; Vietri, Maria Teresa; Cioffi, Michele; Nola, Ernesto; Dell'Aversana, Carmela; Sica, Vincenzo; Molinari, Anna Maria; Altucci, Lucia

    2009-01-01

    Background: BPA (bisphenol A or 2,2-bis(4-hydroxy-phenol)propane) is present in the manufacture of polycarbonate plastic and epoxy resins, which can be used in impact-resistant safety equipment and baby bottles, as protective coatings inside metal food containers, and as composites and sealants in dentistry. Recently, attention has focused on the estrogen-like and carcinogenic adverse effects of BPA. Thus, it is necessary to investigate the cytotoxicity and apoptosis-inducing activity of this compound. Methods: Cell cycle, apoptosis and differentiation analyses; western blots. Results: BPA is able to induce cell cycle arrest and apoptosis in three different acute myeloid leukemias. Although some granulocytic differentiation concomitantly occurred in NB4 cells upon BPA treatment, the major action was the induction of apoptosis. BPA mediated apoptosis was caspase dependent and occurred by activation of extrinsic and intrinsic cell death pathways modulating both FAS and TRAIL and by inducing BAD phosphorylation in NB4 cells. Finally, also non genomic actions such as the early decrease of both ERK and AKT phosphorylation were induced by BPA thus indicating that a complex intersection of regulations occur for the apoptotic action of BPA. Conclusion: BPA is able to induce apoptosis in leukemia cells via caspase activation and involvement of both intrinsic and extrinsic pathways of apoptosis. PMID:19538739

  7. Bisphenol Analogues Other Than BPA: Environmental Occurrence, Human Exposure, and Toxicity-A Review.

    PubMed

    Chen, Da; Kannan, Kurunthachalam; Tan, Hongli; Zheng, Zhengui; Feng, Yong-Lai; Wu, Yan; Widelka, Margaret

    2016-06-01

    Numerous studies have investigated the environmental occurrence, human exposure, and toxicity of bisphenol A (BPA). Following stringent regulations on the production and usage of BPA, several bisphenol analogues have been produced as a replacement for BPA in various applications. The present review outlines the current state of knowledge on the occurrence of bisphenol analogues (other than BPA) in the environment, consumer products and foodstuffs, human exposure and biomonitoring, and toxicity. Whereas BPA was still the major bisphenol analogue found in most environmental monitoring studies, BPF and BPS were also frequently detected. Elevated concentrations of BPAF, BPF, and BPS (i.e., similar to or greater than that of BPA) have been reported in the abiotic environment and human urine from some regions. Many analogues exhibit endocrine disrupting effects, cytotoxicity, genotoxicity, reproductive toxicity, dioxin-like effects, and neurotoxicity in laboratory studies. BPAF, BPB, BPF, and BPS have been shown to exhibit estrogenic and/or antiandrogenic activities similar to or even greater than that of BPA. Knowledge gaps and research needs have been identified, which include the elucidation of environmental occurrences, persistence, and fate of bisphenol analogues (other than BPA), sources and pathways for human exposure, effects on reproductive systems and the mammary gland, mechanisms of toxicity from coexposure to multiple analogues, metabolic pathways and products, and the impact of metabolic modification on toxicity.

  8. Oversight on Community Services Administration, Child Abuse Prevention and Treatment, and Adoption Opportunities, and Native American Programs Act. Hearing before the Subcommittee on Aging, Family and Human Services of the Committee on Labor and Human Resources. United States Senate, Ninety-Seventh Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    Oversight hearings were conducted on April 23, 1981 in reference to social service block grants for the Community Services Administration, child abuse prevention and treatment and adoption programs, and Native American Programs Act. Testimonies for support of block grants advocated ability of States to decide how program resources can best be…

  9. Estrogens in the wrong place at the wrong time: fetal BPA exposure and mammary cancer

    PubMed Central

    Paulose, Tessie; Speroni, Lucia; Sonnenschein, Carlos; Soto, Ana M

    2014-01-01

    Iatrogenic gestational exposure to diethylstilbestrol (DES) induced alterations of the genital tract and predisposed individuals to develop clear cell carcinoma of the vagina as well as breast cancer later in life. Gestational exposure of rodents to a related compound, the xenoestrogen bisphenol-A (BPA) increases the propensity to develop mammary cancer during adulthood, long after cessation of exposure. Exposure to BPA during gestation induces morphological alterations in both the stroma and the epithelium of the fetal mammary gland at 18 days of age. We postulate that the primary target of BPA is the fetal stroma, the only mammary tissue expressing estrogen receptors during fetal life. BPA would then alter the reciprocal stroma-epithelial interactions that mediate mammogenesis. In addition to this direct effect on the mammary gland, BPA is postulated to affect the hypothalamus and thus in turn affect the regulation of mammotropic hormones at puberty and beyond. PMID:25277313

  10. Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function.

    PubMed

    Chen, Yichang; Shu, Le; Qiu, Zhiqun; Lee, Dong Yeon; Settle, Sara J; Que Hee, Shane; Telesca, Donatello; Yang, Xia; Allard, Patrick

    2016-07-01

    Concerns about the safety of Bisphenol A, a chemical found in plastics, receipts, food packaging and more, have led to its replacement with substitutes now found in a multitude of consumer products. However, several popular BPA-free alternatives, such as Bisphenol S, share a high degree of structural similarity with BPA, suggesting that these substitutes may disrupt similar developmental and reproductive pathways. We compared the effects of BPA and BPS on germline and reproductive functions using the genetic model system Caenorhabditis elegans. We found that, similarly to BPA, BPS caused severe reproductive defects including germline apoptosis and embryonic lethality. However, meiotic recombination, targeted gene expression, whole transcriptome and ontology analyses as well as ToxCast data mining all indicate that these effects are partly achieved via mechanisms distinct from BPAs. These findings therefore raise new concerns about the safety of BPA alternatives and the risk associated with human exposure to mixtures. PMID:27472198

  11. Estrogens in the wrong place at the wrong time: Fetal BPA exposure and mammary cancer.

    PubMed

    Paulose, Tessie; Speroni, Lucia; Sonnenschein, Carlos; Soto, Ana M

    2015-07-01

    Iatrogenic gestational exposure to diethylstilbestrol (DES) induced alterations of the genital tract and predisposed individuals to develop clear cell carcinoma of the vagina as well as breast cancer later in life. Gestational exposure of rodents to a related compound, the xenoestrogen bisphenol-A (BPA) increases the propensity to develop mammary cancer during adulthood, long after cessation of exposure. Exposure to BPA during gestation induces morphological alterations in both the stroma and the epithelium of the fetal mammary gland at 18 days of age. We postulate that the primary target of BPA is the fetal stroma, the only mammary tissue expressing estrogen receptors during fetal life. BPA would then alter the reciprocal stroma-epithelial interactions that mediate mammogenesis. In addition to this direct effect on the mammary gland, BPA is postulated to affect the hypothalamus and thus in turn affect the regulation of mammotropic hormones at puberty and beyond.

  12. Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function.

    PubMed

    Chen, Yichang; Shu, Le; Qiu, Zhiqun; Lee, Dong Yeon; Settle, Sara J; Que Hee, Shane; Telesca, Donatello; Yang, Xia; Allard, Patrick

    2016-07-01

    Concerns about the safety of Bisphenol A, a chemical found in plastics, receipts, food packaging and more, have led to its replacement with substitutes now found in a multitude of consumer products. However, several popular BPA-free alternatives, such as Bisphenol S, share a high degree of structural similarity with BPA, suggesting that these substitutes may disrupt similar developmental and reproductive pathways. We compared the effects of BPA and BPS on germline and reproductive functions using the genetic model system Caenorhabditis elegans. We found that, similarly to BPA, BPS caused severe reproductive defects including germline apoptosis and embryonic lethality. However, meiotic recombination, targeted gene expression, whole transcriptome and ontology analyses as well as ToxCast data mining all indicate that these effects are partly achieved via mechanisms distinct from BPAs. These findings therefore raise new concerns about the safety of BPA alternatives and the risk associated with human exposure to mixtures.

  13. Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function

    PubMed Central

    Chen, Yichang; Qiu, Zhiqun; Lee, Dong Yeon; Telesca, Donatello; Yang, Xia; Allard, Patrick

    2016-01-01

    Concerns about the safety of Bisphenol A, a chemical found in plastics, receipts, food packaging and more, have led to its replacement with substitutes now found in a multitude of consumer products. However, several popular BPA-free alternatives, such as Bisphenol S, share a high degree of structural similarity with BPA, suggesting that these substitutes may disrupt similar developmental and reproductive pathways. We compared the effects of BPA and BPS on germline and reproductive functions using the genetic model system Caenorhabditis elegans. We found that, similarly to BPA, BPS caused severe reproductive defects including germline apoptosis and embryonic lethality. However, meiotic recombination, targeted gene expression, whole transcriptome and ontology analyses as well as ToxCast data mining all indicate that these effects are partly achieved via mechanisms distinct from BPAs. These findings therefore raise new concerns about the safety of BPA alternatives and the risk associated with human exposure to mixtures. PMID:27472198

  14. Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study.

    PubMed

    Rebuli, Meghan E; Camacho, Luísa; Adonay, Maria E; Reif, David M; Aylor, David L; Patisaul, Heather B

    2015-12-01

    Bisphenol A (BPA) is a high volume production chemical and has been identified as an endocrine disruptor, prompting concern that developmental exposure could impact brain development and behavior. Rodent and human studies suggest that early life BPA exposure may result in an anxious, hyperactive phenotype but results are conflicting and data from studies using multiple doses below the no-observed-adverse-effect level are limited. To address this, the present studies were conducted as part of the CLARITY-BPA (Consortium Linking Academic and Regulatory Insights on BPA Toxicity) program. The impact of perinatal BPA exposure (2.5, 25, or 2500 µg/kg body weight (bw)/day) on behaviors related to anxiety and exploratory activity was assessed in juvenile (prepubertal) and adult NCTR Sprague-Dawley rats of both sexes. Ethinyl estradiol (0.5 µg/kg bw/day) was used as a reference estrogen. Exposure spanned gestation and lactation with dams gavaged from gestational day 6 until birth and then the offspring gavaged directly through weaning (n = 12/sex/group). Behavioral assessments included open field, elevated plus maze, and zero maze. Anticipated sex differences in behavior were statistically identified or suggested in most cases. No consistent effects of BPA were observed for any endpoint, in either sex, at either age compared to vehicle controls; however, significant differences between BPA-exposed and ethinyl estradiol-exposed groups were identified for some endpoints. Limitations of this study are discussed and include suboptimal statistical power and low concordance across behavioral tasks. These data do not indicate BPA-related effects on anxiety or exploratory activity in these developmentally exposed rats.

  15. Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study.

    PubMed

    Rebuli, Meghan E; Camacho, Luísa; Adonay, Maria E; Reif, David M; Aylor, David L; Patisaul, Heather B

    2015-12-01

    Bisphenol A (BPA) is a high volume production chemical and has been identified as an endocrine disruptor, prompting concern that developmental exposure could impact brain development and behavior. Rodent and human studies suggest that early life BPA exposure may result in an anxious, hyperactive phenotype but results are conflicting and data from studies using multiple doses below the no-observed-adverse-effect level are limited. To address this, the present studies were conducted as part of the CLARITY-BPA (Consortium Linking Academic and Regulatory Insights on BPA Toxicity) program. The impact of perinatal BPA exposure (2.5, 25, or 2500 µg/kg body weight (bw)/day) on behaviors related to anxiety and exploratory activity was assessed in juvenile (prepubertal) and adult NCTR Sprague-Dawley rats of both sexes. Ethinyl estradiol (0.5 µg/kg bw/day) was used as a reference estrogen. Exposure spanned gestation and lactation with dams gavaged from gestational day 6 until birth and then the offspring gavaged directly through weaning (n = 12/sex/group). Behavioral assessments included open field, elevated plus maze, and zero maze. Anticipated sex differences in behavior were statistically identified or suggested in most cases. No consistent effects of BPA were observed for any endpoint, in either sex, at either age compared to vehicle controls; however, significant differences between BPA-exposed and ethinyl estradiol-exposed groups were identified for some endpoints. Limitations of this study are discussed and include suboptimal statistical power and low concordance across behavioral tasks. These data do not indicate BPA-related effects on anxiety or exploratory activity in these developmentally exposed rats. PMID:26209558

  16. Assessing bisphenol A (BPA) exposure risk from long-term dietary intakes in Taiwan.

    PubMed

    Chen, Wei-Yu; Shen, Yi-Pei; Chen, Szu-Chieh

    2016-02-01

    Dietary intake is the major bisphenol A (BPA) exposure route in humans, and is a cause of BPA-related adverse effects. The large-scale exposure risk of humans to BPA through dietary sources in Taiwan is less well studied. The aim of this study was to assess the average daily dose (ADD) and hazardous quotient (HQ) of BPA exposure risk from long-term dietary intake of BPA, as well as BPA concentrations in different age-sex groups in Taiwan. We reanalyzed the BPA concentrations of regular daily food sources (rice, poultry, livestock, seafood, protein, fruits, and vegetables) and used a national dietary survey to estimate the contribution of variance to ADDs and potential human health effect for different age-sex groups. This study found that the daily consumption of chicken, pork/beef, and seafood were estimated to be 33.77 (Male)/22.65 (Female), 91.70 (M)/66.35 (F), and 54.15 (M)/40.78 (F) g/day, respectively. The highest BPA ADD was found in the 6-9 years age group (95% CI=0.0006-0.0027 mg/kg-bw/day), whereas the lowest BPA ADD was in the ≥65 years age group (0.0002-0.0020 mg/kg-bw/day). Based on the latest EFSA guidelines (0.004 mg/kg-bw/day), the 97.5 percentile HQ of BPA intake in different age-sex groups in Taiwan posed no risks through dietary intake. However, a combination of multiple exposure routes and long-term exposure in specific populations may be of concern in the future. PMID:26580736

  17. BPA Directly Decreases GnRH Neuronal Activity via Noncanonical Pathway.

    PubMed

    Klenke, Ulrike; Constantin, Stephanie; Wray, Susan

    2016-05-01

    Peripheral feedback of gonadal estrogen to the hypothalamus is critical for reproduction. Bisphenol A (BPA), an environmental pollutant with estrogenic actions, can disrupt this feedback and lead to infertility in both humans and animals. GnRH neurons are essential for reproduction, serving as an important link between brain, pituitary, and gonads. Because GnRH neurons express several receptors that bind estrogen, they are potential targets for endocrine disruptors. However, to date, direct effects of BPA on GnRH neurons have not been shown. This study investigated the effects of BPA on GnRH neuronal activity using an explant model in which large numbers of primary GnRH neurons are maintained and express many of the receptors found in vivo. Because oscillations in intracellular calcium have been shown to correlate with electrical activity in GnRH neurons, calcium imaging was used to assay the effects of BPA. Exposure to 50μM BPA significantly decreased GnRH calcium activity. Blockage of γ-aminobutyric acid ergic and glutamatergic input did not abrogate the inhibitory BPA effect, suggesting direct regulation of GnRH neurons by BPA. In addition to estrogen receptor-β, single-cell RT-PCR analysis confirmed that GnRH neurons express G protein-coupled receptor 30 (G protein-coupled estrogen receptor 1) and estrogen-related receptor-γ, all potential targets for BPA. Perturbation studies of the signaling pathway revealed that the BPA-mediated inhibition of GnRH neuronal activity occurred independent of estrogen receptors, GPER, or estrogen-related receptor-γ, via a noncanonical pathway. These results provide the first evidence of a direct effect of BPA on GnRH neurons. PMID:26934298

  18. BPA Directly Decreases GnRH Neuronal Activity via Noncanonical Pathway.

    PubMed

    Klenke, Ulrike; Constantin, Stephanie; Wray, Susan

    2016-05-01

    Peripheral feedback of gonadal estrogen to the hypothalamus is critical for reproduction. Bisphenol A (BPA), an environmental pollutant with estrogenic actions, can disrupt this feedback and lead to infertility in both humans and animals. GnRH neurons are essential for reproduction, serving as an important link between brain, pituitary, and gonads. Because GnRH neurons express several receptors that bind estrogen, they are potential targets for endocrine disruptors. However, to date, direct effects of BPA on GnRH neurons have not been shown. This study investigated the effects of BPA on GnRH neuronal activity using an explant model in which large numbers of primary GnRH neurons are maintained and express many of the receptors found in vivo. Because oscillations in intracellular calcium have been shown to correlate with electrical activity in GnRH neurons, calcium imaging was used to assay the effects of BPA. Exposure to 50μM BPA significantly decreased GnRH calcium activity. Blockage of γ-aminobutyric acid ergic and glutamatergic input did not abrogate the inhibitory BPA effect, suggesting direct regulation of GnRH neurons by BPA. In addition to estrogen receptor-β, single-cell RT-PCR analysis confirmed that GnRH neurons express G protein-coupled receptor 30 (G protein-coupled estrogen receptor 1) and estrogen-related receptor-γ, all potential targets for BPA. Perturbation studies of the signaling pathway revealed that the BPA-mediated inhibition of GnRH neuronal activity occurred independent of estrogen receptors, GPER, or estrogen-related receptor-γ, via a noncanonical pathway. These results provide the first evidence of a direct effect of BPA on GnRH neurons.

  19. Assessing bisphenol A (BPA) exposure risk from long-term dietary intakes in Taiwan.

    PubMed

    Chen, Wei-Yu; Shen, Yi-Pei; Chen, Szu-Chieh

    2016-02-01

    Dietary intake is the major bisphenol A (BPA) exposure route in humans, and is a cause of BPA-related adverse effects. The large-scale exposure risk of humans to BPA through dietary sources in Taiwan is less well studied. The aim of this study was to assess the average daily dose (ADD) and hazardous quotient (HQ) of BPA exposure risk from long-term dietary intake of BPA, as well as BPA concentrations in different age-sex groups in Taiwan. We reanalyzed the BPA concentrations of regular daily food sources (rice, poultry, livestock, seafood, protein, fruits, and vegetables) and used a national dietary survey to estimate the contribution of variance to ADDs and potential human health effect for different age-sex groups. This study found that the daily consumption of chicken, pork/beef, and seafood were estimated to be 33.77 (Male)/22.65 (Female), 91.70 (M)/66.35 (F), and 54.15 (M)/40.78 (F) g/day, respectively. The highest BPA ADD was found in the 6-9 years age group (95% CI=0.0006-0.0027 mg/kg-bw/day), whereas the lowest BPA ADD was in the ≥65 years age group (0.0002-0.0020 mg/kg-bw/day). Based on the latest EFSA guidelines (0.004 mg/kg-bw/day), the 97.5 percentile HQ of BPA intake in different age-sex groups in Taiwan posed no risks through dietary intake. However, a combination of multiple exposure routes and long-term exposure in specific populations may be of concern in the future.

  20. Perceptions of behavioral health care among veterans with substance use disorders: results from a national evaluation of mental health services in the Veterans Health Administration.

    PubMed

    Blonigen, Daniel M; Bui, Leena; Harris, Alex H S; Hepner, Kimberly A; Kivlahan, Daniel R

    2014-08-01

    Understanding patients' perceptions of care is essential for health care systems. We examined predictors of perceptions of behavioral health care (satisfaction with care, helpfulness of care, and perceived improvement) among veterans with substance use disorders (SUD; n = 1,581) who participated in a phone survey as part of a national evaluation of mental health services in the U.S. Veterans Health Administration. In multivariate analyses, SUD specialty care utilization and higher mental health functioning were associated positively with all perceptions of care, and comorbid schizophrenia, bipolar, and PTSD were associated positively with multiple perceptions of care. Perceived helpfulness of care was associated with receipt of SUD specialty care in the prior 12 months (adjusted OR = 1.77, p<.001). Controlling for patient characteristics, satisfaction with care exhibited strong associations with perceptions of staff as supportive and empathic, whereas perceived improvement was strongly linked to the perception that staff helped patients develop goals beyond symptom management. Survey responses that account for variation in SUD patients' perceptions of care could inform and guide quality improvement efforts with this population.

  1. Design of Studies for Development of BPA Fish and Wildlife Mitigation Accounting Policy Phase II, Volume II, 1985-1988 Technical Report.

    SciTech Connect

    Kneese, Allen V.

    1988-08-01

    The incremental costs of corrective measures to lessen the environmental impacts of the hydroelectric system are expected to increase and difficult questions to arise about the costs, effectiveness, and justification of alternative measures and their systemwide implications. The BPA anticipate this situation by launching a forward-looking research program aimed at providing methodological tools and data suitable for estimating the productivity and cost implications of mitigation alternatives in a timely manner with state-of-the-art accuracy. Resources for the Future (RFF) agreed at the request of the BPA to develop a research program which would provide an analytical system designed to assist the BPA Administrator and other interested and responsible parties in evaluating the ecological and economic aspects of alternative protection, enhancement, and mitigation measures. While this progression from an ecological understanding to cost-effectiveness analyses is straightforward in concept, the complexities of the Columbia River system make the development of analytical methods far from simple in practice. The Phase 2 final report outlines the technical issues involved in developing an analytical system and proposes a program of research to address these issues. The report is presented in the Summary Report (Volume 1), and the present volume which consists of three technical reports: Part I, Modeling the Salmon and Steelhead Fisheries of the Columbia River Basin; Part II, Models for Cost-Effectiveness Analysis; and Part III, Ocean Fisheries Harvest Management.

  2. Goldstone (GDSCC) administrative computing

    NASA Technical Reports Server (NTRS)

    Martin, H.

    1981-01-01

    The GDSCC Data Processing Unit provides various administrative computing services for Goldstone. Those activities, including finance, manpower and station utilization, deep-space station scheduling and engineering change order (ECO) control are discussed.

  3. 7 CFR 3431.20 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.20 Administration. The VMLRP will be administered by...

  4. Medical emergency teams are associated with reduced mortality across a major metropolitan health network after two years service: a retrospective study using government administrative data

    PubMed Central

    2012-01-01

    Introduction Medical emergency teams (MET) are implemented to ensure prompt clinical review of patients with deteriorating physiology with the intention of averting further deterioration, cardiac arrest and death. We sought to determine if MET implementation has led to reductions in hospital mortality across a large metropolitan health network utilising routine administrative data submitted by hospitals to the Department of Health Victoria. Methods The Victorian admissions episodes data set (VAED) contains data on all individual hospital separations in the State of Victoria, Australia. After gaining institutional ethics approval, we extracted data on all acute admissions to metropolitan hospitals for which we had information on the presence and timing of a MET system. Using logistic regression we determined whether there was an effect of MET implementation on mortality controlling for age, gender, Charlson comorbidity diagnostic groupings, emergency admission, same day admission, ICU admission, mechanical ventilation, year, indigenous ethnicity, liaison nurse service and hospital designation. Results 5911533 individual admissions and 73,599 associated deaths from July 1999 to June 2010 were included in the analysis. 52.2% were male and median age was 57(42-72 IQR). Mortality rates for MET and non-MET periods were 3.92 (3.88-3.95 95%CI) and 4.56 (4.51-4.61 95%CI) deaths per 1000 patient days with a rate ratio after adjustment for year of 0.88 (0.86-0.89 95%CI) P < 0.001. In a multivariable logistic regression, mortality was associated with a MET team being active in the hospital for more than 2 years. The odds ratio for mortality in hospitals where a MET system had been in place for greater than 4 years duration was 0.90 (0.88-0.92). Mortality during the first 2 years of a MET system being in place was not statistically different from pre-MET periods. Conclusions Utilising routinely collected administrative data we demonstrated that the presence of a hospital MET

  5. Federal Agency and Federal Library Reports: Library of Congress; Center for the Book; Federal Library and Information Center Committee; National Agricultural Library; National Library of Medicine; United States Government Printing Office; National Technical Information Service; National Archives and Records Administration; National Center for Education Statistics Library Statistics Program; National Commission on Libraries and Information Science; National Library of Education; Educational Resources Information Center.

    ERIC Educational Resources Information Center

    Fischer, Audrey; Cole, John Y.; Tarr, Susan M.; Carey, Len; Mehnert, Robert; Sherman, Andrew M.; Davis, Linda; Leahy, Debra W.; Chute, Adrienne; Willard, Robert S.; Dunn, Christina

    2003-01-01

    Includes annual reports from 12 federal agencies and libraries that discuss security, budgets, legislation, digital projects, preservation, government role, information management, personnel changes, collections, databases, financial issues, services, administration, Web sites, access to information, customer service, statistics, international…

  6. Are typical human serum BPA concentrations measurable and sufficient to be estrogenic in the general population?

    PubMed

    Teeguarden, Justin; Hanson-Drury, Sesha; Fisher, Jeffrey W; Doerge, Daniel R

    2013-12-01

    Mammalian estrogen receptors modulate many physiological processes. Chemicals with structural features similar to estrogens can interact with estrogen receptors to produce biological effects similar to those caused by endogenous estrogens in the body. Bisphenol A (BPA) is a structural analogue of estrogen that binds to estrogen receptors. Exposure to BPA in humans is virtually ubiquitous in industrialized societies, but BPA is rapidly detoxified by metabolism and does not accumulate in the body. Whether or not serum concentrations of BPA in humans are sufficiently high to disrupt normal estrogen-related biology is the subject of intense political and scientific debate. Here we show a convergence of robust methods for measuring or calculating serum concentrations of BPA in humans from 93 published studies of more than 30,000 individuals in 19 countries across all life stages. Typical serum BPA concentrations are orders of magnitude lower than levels measurable by modern analytical methods and below concentrations required to occupy more than 0.0009% of Type II Estrogen Binding Sites, GPR30, ERα or ERβ receptors. Occupancies would be higher, but ≤0.04%, for the highest affinity receptor, ERRγ. Our results show limited or no potential for estrogenicity in humans, and question reports of measurable BPA in human serum.

  7. Toxicogenomic analysis of placenta samples from mice exposed to different doses of BPA.

    PubMed

    Tait, Sabrina; Tassinari, Roberta; Maranghi, Francesca; Mantovani, Alberto

    2015-06-01

    Bisphenol A (BPA), a widespread Endocrine Disrupter mainly used in food contact plastics, may induce adverse effects especially on susceptible lifestages, first of all pregnancy. The present study considered placental development as a potential target of BPA and investigated potential differences in the modes of action of two doses of BPA by a toxicogenomic approach. Pregnant CD-1 mice were administered with vehicle, 0.5 (BPA05) or 50 mg/kg (BPA50) body weight (bw)/die of BPA, from gestational day (GD) 1 to GD11. At GD12 dams were sacrificed and transcriptomic analysis was performed on placenta samples. Histological, histomorphometrical and immunohistochemical analyses were also performed to phenotypically anchor transcriptional changes associated with BPA exposure. The interpretation and description of the overall data are included in a manuscript under revision [1]. Here we describe the experimental design and the analysis performed on the gene expression data which are publicly available through the Gene Expression Omnibus (GEO) database with accession number GSE63852.

  8. Probabilistic modeling of school meals for potential bisphenol A (BPA) exposure.

    PubMed

    Hartle, Jennifer C; Fox, Mary A; Lawrence, Robert S

    2016-01-01

    Many endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA), are approved for use in food packaging, with unbound BPA migrating into the foods it contacts. Children, with their developing organ systems, are especially susceptible to hormone disruption, prompting this research to model the potential dose of BPA from school-provided meals. Probabilistic exposure models for school meals were informed by mixed methods. Exposure scenarios were based on United States school nutrition guidelines and included meals with varying levels of exposure potential from canned and packaged food. BPA exposure potentials were modeled with a range of 0.00049 μg/kg-BW/day for a middle school student with a low exposure breakfast and plate waste to 1.19 μg/kg-BW/day for an elementary school student eating lunch with high exposure potential. The modeled BPA doses from school meals are below the current US EPA Oral Reference Dose (RfD) of 50 μg/kg-BW/day. Recent research shows BPA animal toxicity thresholds at 2 μg/kg-BW/day. The single meal doses modeled in this research are at the same order of magnitude as the low-dose toxicity thresholds, illustrating the potential for school meals to expose children to chronic toxic levels of BPA.

  9. Toxicogenomic analysis of placenta samples from mice exposed to different doses of BPA.

    PubMed

    Tait, Sabrina; Tassinari, Roberta; Maranghi, Francesca; Mantovani, Alberto

    2015-06-01

    Bisphenol A (BPA), a widespread Endocrine Disrupter mainly used in food contact plastics, may induce adverse effects especially on susceptible lifestages, first of all pregnancy. The present study considered placental development as a potential target of BPA and investigated potential differences in the modes of action of two doses of BPA by a toxicogenomic approach. Pregnant CD-1 mice were administered with vehicle, 0.5 (BPA05) or 50 mg/kg (BPA50) body weight (bw)/die of BPA, from gestational day (GD) 1 to GD11. At GD12 dams were sacrificed and transcriptomic analysis was performed on placenta samples. Histological, histomorphometrical and immunohistochemical analyses were also performed to phenotypically anchor transcriptional changes associated with BPA exposure. The interpretation and description of the overall data are included in a manuscript under revision [1]. Here we describe the experimental design and the analysis performed on the gene expression data which are publicly available through the Gene Expression Omnibus (GEO) database with accession number GSE63852. PMID:26484192

  10. Probabilistic modeling of school meals for potential bisphenol A (BPA) exposure.

    PubMed

    Hartle, Jennifer C; Fox, Mary A; Lawrence, Robert S

    2016-01-01

    Many endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA), are approved for use in food packaging, with unbound BPA migrating into the foods it contacts. Children, with their developing organ systems, are especially susceptible to hormone disruption, prompting this research to model the potential dose of BPA from school-provided meals. Probabilistic exposure models for school meals were informed by mixed methods. Exposure scenarios were based on United States school nutrition guidelines and included meals with varying levels of exposure potential from canned and packaged food. BPA exposure potentials were modeled with a range of 0.00049 μg/kg-BW/day for a middle school student with a low exposure breakfast and plate waste to 1.19 μg/kg-BW/day for an elementary school student eating lunch with high exposure potential. The modeled BPA doses from school meals are below the current US EPA Oral Reference Dose (RfD) of 50 μg/kg-BW/day. Recent research shows BPA animal toxicity thresholds at 2 μg/kg-BW/day. The single meal doses modeled in this research are at the same order of magnitude as the low-dose toxicity thresholds, illustrating the potential for school meals to expose children to chronic toxic levels of BPA. PMID:26395857

  11. Endocrine activity of alternatives to BPA found in thermal paper in Switzerland.

    PubMed

    Goldinger, Daniela M; Demierre, Anne-Laure; Zoller, Otmar; Rupp, Heinz; Reinhard, Hans; Magnin, Roxane; Becker, Thomas W; Bourqui-Pittet, Martine

    2015-04-01

    Alternatives to bisphenol A (BPA) are more and more used in thermal paper receipts. To get an overview of the situation in Switzerland, 124 thermal paper receipts were collected and analyzed. Whereas BPA was detected in most samples (n=100), some alternatives, namely bisphenol S (BPS), Pergafast® 201 and D-8 have been found in 4, 11 and 9 samples respectively. As no or few data on their endocrine activity are available, these chemicals and bisphenol F (BPF) were tested in vitro using the H295R steroidogenesis assay. 17β-Estradiol production was induced by BPA and BPF, whereas free testosterone production was inhibited by BPA and BPS. Both non-bisphenol substances did not show significant effects. The binding affinity to 16 proteins and the toxicological potential (TP) were further calculated in silico using VirtualToxLab™. TP values lay between 0.269 and 0.476 and the main target was the estrogen receptor β (84.4 nM to 1.33 μM). A substitution of BPA by BPF and BPS should be thus considered with caution, since they exhibit almost a similar endocrine activity as BPA. D-8 and Pergafast® 201 could be alternatives to replace BPA, however further analyses are needed to better characterize their effects on the hormonal system.

  12. Dental students' HIV/AIDS-related knowledge, attitudes, and intentions: impact of the U.S. Health Resources and Services Administration's community-based dental partnership program.

    PubMed

    Hamershock, Rose A; Rajabiun, Serena; Fox, Jane E; Mofidi, Mahyar; Abel, Stephen N; York, Jill A; Kunzel, Carol; Sanogo, Moussa; Mayfield, Theresa G

    2014-08-01

    Access to oral health care for vulnerable populations is one of the concerns addressed by the U.S. Health Resources and Services Administration HIV/AIDS Bureau's Community-Based Dental Partnership Program (CBDPP). The program introduces dental students and residents at several dental schools to care for vulnerable patients through didactic and clinical work in community-based dental settings. This study of the dental students and residents in this program answered three questions: 1) What are their HIV knowledge, attitudes, and behaviors? 2) How has participation in the CBDPP impacted their knowledge, attitudes, and behaviors? 3) Has the intervention affected their work placement decisions and attitudes after graduation, particularly with respect to treating people living with HIV and other underserved populations? A total of 305 first- through fourth-year dental students and first- and second-year residents at five dental schools across the United States completed surveys before and after a community-based rotation and following graduation. Response rates at each of the five schools ranged from 82.4 to 100 percent. The results showed an increase in the participants' knowledge and positive attitudes regarding treatment for patients with HIV and other vulnerable populations post-rotation compared to pre-rotation. Results after graduation found that most respondents were practicing in private settings or in academic institutions as residents but were willing to treat a diverse patient population. These findings support the role of training programs, such as the CBDPP, for expanding the dental workforce to treating vulnerable populations including people living with HIV/AIDS.

  13. Dental students' HIV/AIDS-related knowledge, attitudes, and intentions: impact of the U.S. Health Resources and Services Administration's community-based dental partnership program.

    PubMed

    Hamershock, Rose A; Rajabiun, Serena; Fox, Jane E; Mofidi, Mahyar; Abel, Stephen N; York, Jill A; Kunzel, Carol; Sanogo, Moussa; Mayfield, Theresa G

    2014-08-01

    Access to oral health care for vulnerable populations is one of the concerns addressed by the U.S. Health Resources and Services Administration HIV/AIDS Bureau's Community-Based Dental Partnership Program (CBDPP). The program introduces dental students and residents at several dental schools to care for vulnerable patients through didactic and clinical work in community-based dental settings. This study of the dental students and residents in this program answered three questions: 1) What are their HIV knowledge, attitudes, and behaviors? 2) How has participation in the CBDPP impacted their knowledge, attitudes, and behaviors? 3) Has the intervention affected their work placement decisions and attitudes after graduation, particularly with respect to treating people living with HIV and other underserved populations? A total of 305 first- through fourth-year dental students and first- and second-year residents at five dental schools across the United States completed surveys before and after a community-based rotation and following graduation. Response rates at each of the five schools ranged from 82.4 to 100 percent. The results showed an increase in the participants' knowledge and positive attitudes regarding treatment for patients with HIV and other vulnerable populations post-rotation compared to pre-rotation. Results after graduation found that most respondents were practicing in private settings or in academic institutions as residents but were willing to treat a diverse patient population. These findings support the role of training programs, such as the CBDPP, for expanding the dental workforce to treating vulnerable populations including people living with HIV/AIDS. PMID:25086143

  14. Quantitative determination of free and total bisphenol A in human urine using labeled BPA glucuronide and isotope dilution mass spectrometry.

    PubMed

    Kubwabo, Cariton; Kosarac, Ivana; Lalonde, Kaela; Foster, Warren G

    2014-07-01

    Bisphenol A (BPA) is a widely used industrial chemical in the manufacturing of polycarbonate plastic bottles, food and beverage can linings, thermal receipts, and dental sealants. Animal and human studies suggest that BPA may disrupt normal hormonal function and hence, potentially, have negative effects on the human health. While total BPA is frequently reported, it is recognized that free BPA is the biologically active form and is rarely reported in the literature. The objective of this study was to develop a sensitive and improved method for the measurement of free and total BPA in human urine. Use of a labeled conjugated BPA (bisphenol A-d6 β-D-glucuronide) allowed for the optimization of the enzymatic reaction and permitted an accurate determination of the conjugated BPA concentration in urine samples. In addition, a (13)C12-BPA internal standard was used to account for the analytical recoveries and performance of the isotope dilution method. Solid-phase extraction (SPE) combined with derivatization and analysis using a triple quadrupole GC-EI/MS/MS system achieved very low method detection limit of 0.027 ng/mL. BPA concentrations were measured in urine samples collected during the second and third trimesters of pregnancy in 36 Canadian women. Total maternal BPA concentrations in urine samples ranged from not detected to 9.40 ng/mL (median, 1.21 ng/mL), and free BPA concentrations ranged from not detected to 0.950 ng/mL (median, 0.185 ng/mL). Eighty-six percent of the women had detectable levels of conjugated BPA, whereas only 22 % had detectable levels of free BPA in their urine. BPA levels measured in this study agreed well with data reported internationally.

  15. Hospital Library Administration.

    ERIC Educational Resources Information Center

    Cramer, Anne

    The objectives of a hospital are to improve patient care, while the objectives of a hospital library are to improve services to the staff which will support their efforts. This handbook dealing with hospital administration is designed to aid the librarian in either implementing a hospital library, or improving services in an existing medical…

  16. Inspection of surveillance activities and administrative leave policy at Bonneville Power Administration, Portland, Oregon

    SciTech Connect

    Not Available

    1994-04-01

    The authors conducted an inspection of surveillance activities and administrative leave policy at the Bonneville Power Administration, Portland, Oregon. The purpose of their inspection was to determine if a covert video surveillance operation conducted at Bonneville Power Administration was consistent with Department of Energy policies and procedures and other applicable regulations and procedures, and to determine if administrative leave policies and procedures used at Bonneville Power Administration in a specific instance were consistent with Department of Energy requirements and the Code of Federal Regulations. This inspection focused on a specific incident that occurred in 1989 on the 5th floor of the BPA Headquarters Building located in Portland, Oregon. The incident involved the soiling of an employee`s personal property with what appeared to be urine.

  17. Biodistribution of the boron carriers boronophenylalanine (BPA) and/or decahydrodecaborate (GB-10) for Boron Neutron Capture Therapy (BNCT) in an experimental model of lung metastases

    SciTech Connect

    D.W. Nigg; Various Others

    2014-06-01

    BNCT was proposed for the treatment of diffuse, non-resectable tumors in the lung. We performed boron biodistribution studies with 5 administration protocols employing the boron carriers BPA and/or GB-10 in an experimental model of disseminated lung metastases in rats. All 5 protocols were non-toxic and showed preferential tumor boron uptake versus lung. Absolute tumor boron concentration values were therapeutically useful (25–76 ppm) for 3 protocols. Dosimetric calculations indicate that BNCT at RA-3 would be potentially therapeutic without exceeding radiotolerance in the lung.

  18. 48 CFR 808.405-2 - Ordering procedure for services requiring a statement of work.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Federal Supply Schedules 808.405-2 Ordering procedure for services requiring a statement of work. When placing an order or establishing a BPA for supplies or services requiring a statement of work, the... services requiring a statement of work. 808.405-2 Section 808.405-2 Federal Acquisition Regulations...

  19. 48 CFR 808.405-2 - Ordering procedure for services requiring a statement of work.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Federal Supply Schedules 808.405-2 Ordering procedure for services requiring a statement of work. When placing an order or establishing a BPA for supplies or services requiring a statement of work, the... services requiring a statement of work. 808.405-2 Section 808.405-2 Federal Acquisition Regulations...

  20. 48 CFR 808.405-2 - Ordering procedure for services requiring a statement of work.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Federal Supply Schedules 808.405-2 Ordering procedure for services requiring a statement of work. When placing an order or establishing a BPA for supplies or services requiring a statement of work, the... services requiring a statement of work. 808.405-2 Section 808.405-2 Federal Acquisition Regulations...

  1. 48 CFR 808.405-2 - Ordering procedure for services requiring a statement of work.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Federal Supply Schedules 808.405-2 Ordering procedure for services requiring a statement of work. When placing an order or establishing a BPA for supplies or services requiring a statement of work, the... services requiring a statement of work. 808.405-2 Section 808.405-2 Federal Acquisition Regulations...

  2. 48 CFR 808.405-2 - Ordering procedure for services requiring a statement of work.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Federal Supply Schedules 808.405-2 Ordering procedure for services requiring a statement of work. When placing an order or establishing a BPA for supplies or services requiring a statement of work, the... services requiring a statement of work. 808.405-2 Section 808.405-2 Federal Acquisition Regulations...

  3. A Basic Manual for Physical Plant Administration.

    ERIC Educational Resources Information Center

    Weber, George O., Ed.; Fincham, Michael W., Ed.

    This book provides practical advice on problems of institutional plant management to physical plant administrators. Areas covered include the role, organization, and facilities of the physical plant department; personnel administration; financial administration; buildings maintenance and operation; custodial services; utilities distribution…

  4. Enhancing Skin Permeation of Biphenylacetic Acid (BPA) Using Salt Formation with Organic and Alkali Metal Bases.

    PubMed

    Pawar, Vijay; Naik, Prashant; Giridhar, Rajani; Yadav, Mange Ram

    2015-01-01

    In the present study, a series of organic and alkali metal salts of biphenylacetic acid (BPA) have been prepared and evaluated in vitro for percutaneous drug delivery. The physicochemical properties of BPA salts were determined using solubility measurements, DSC, and IR. The DSC thermogram and FTIR spectra confirmed the salt formation with organic and alkali metal bases. Among the series, salts with organic amines (ethanolamine, diethanolamine, triethanolamine, and diethylamine) had lowered melting points while the alkali metal salt (sodium) had a higher melting point than BPA. The in vitro study showed that salt formation improves the physicochemical properties of BPA, leading to improved permeability through the skin. Amongst all the prepared salts, ethanolamine salt (1b) showed 7.2- and 5.4-fold higher skin permeation than the parent drug at pH 7.4 and 5.0, respectively, using rat skin.

  5. Administrators' Beliefs/Preferences for Delivering Higher Education Counseling Services and the Relationship between the Domains of Career and Personal Counseling

    ERIC Educational Resources Information Center

    Waters, Sharon K.

    2012-01-01

    An examination of the relationship between the domains of career and personal counseling within higher education was conducted through surveying administrators of these departments with emphasis toward determining factors that contribute toward administrators' beliefs and preferences regarding an integrated (personal and career counseling)…

  6. Bisphenol A (BPA) in food contact materials - new scientific opinion from EFSA regarding public health risk.

    PubMed

    Ćwiek-Ludwicka, Kazimiera

    2015-01-01

    The wide use of bisphenol A (BPA) as a monomer in plastics manufacture or epoxy resins intended for food contact materials (FCM) has triggered numerous concerns due to toxicological findings indicating possible endocrine disrupting properties. This article traces the evolution of the scientific opinions since 1986 when the Tolerable Daily Intake (TDI) for BPA and its specific migration limit (SML) from plastic FCM into food were proposed for the first time by the Scientific Committee for Food (SCF). Resent extensive scientific studies concerning refined data on toxicity and exposure to BPA from food and non-food sources (eg. dust, cosmetics, thermal paper), including the most vulnerable groups of population, allowed the European Food Safety Authority (EFSA) to reduce the TDI of BPA from previously 50 µg/kg bw/day to now 4 µg/kg bw/day. EFSA's latest scientific opinion published in 2015 concludes that basing on the current estimations of total exposure to BPA from dietary and non-dietary sources for infants, children and adolescents is below the temporary TDI of 4 μg/kg bw/day. EFSA has also underlined that BPA poses no health risk at the estimated exposure levels of any population age group, including unborn children and the elderly. However, EFSA has indicated that some data on exposure and toxicological effects still require clarifications. PMID:26656411

  7. Simultaneous adsorption of Cd²⁺ and BPA on amphoteric surfactant activated montmorillonite.

    PubMed

    Liu, Chongmin; Wu, Pingxiao; Zhu, Yajie; Tran, Lytuong

    2016-02-01

    The study mainly investigated the simultaneous adsorption of bisphenol A (BPA) and Cd(2+) from aqueous solution on octadecane-betaine modified montmorillonite (BS-Mt). The characteristics of the obtained materials were analyzed by X-ray diffraction (XRD), Fourier-transform infrared (FTIR), Specific surface area (BET) and Scanning electron microscopy/Energy disperse spectroscopy (SEM/EDS), confirming that BS-18 was successfully introduced into Mt. Also, factors including initial solution pH, initial Cd(2+)/BPA concentration, contact time and adsorbent dosage on the adsorption processes were shown to be crucial for Cd(2+) adsorption, whereas had negligible effects on BPA adsorption. In this study, we found that pseudo-second-order model fitted well with the adsorption kinetic studies for both Cd(2+) and BPA with an equilibrium time of 24 h. The Cd(2+) and BPA adsorption isotherm could be well described by Freundlich model and Langmuir model, respectively. On the basis of kinetic models, the maximum adsorption capacity of Cd(2+) in aqueous solution was slightly enhanced after modification, indicating that Cd(2+) adsorption on BS-Mt was mainly attributed to direct electrostatic attraction and the chelate reaction, while the dramatic enhancement of maximum adsorption capacity for BPA was due to the hydrophobic interaction.

  8. Simultaneous adsorption of Cd²⁺ and BPA on amphoteric surfactant activated montmorillonite.

    PubMed

    Liu, Chongmin; Wu, Pingxiao; Zhu, Yajie; Tran, Lytuong

    2016-02-01

    The study mainly investigated the simultaneous adsorption of bisphenol A (BPA) and Cd(2+) from aqueous solution on octadecane-betaine modified montmorillonite (BS-Mt). The characteristics of the obtained materials were analyzed by X-ray diffraction (XRD), Fourier-transform infrared (FTIR), Specific surface area (BET) and Scanning electron microscopy/Energy disperse spectroscopy (SEM/EDS), confirming that BS-18 was successfully introduced into Mt. Also, factors including initial solution pH, initial Cd(2+)/BPA concentration, contact time and adsorbent dosage on the adsorption processes were shown to be crucial for Cd(2+) adsorption, whereas had negligible effects on BPA adsorption. In this study, we found that pseudo-second-order model fitted well with the adsorption kinetic studies for both Cd(2+) and BPA with an equilibrium time of 24 h. The Cd(2+) and BPA adsorption isotherm could be well described by Freundlich model and Langmuir model, respectively. On the basis of kinetic models, the maximum adsorption capacity of Cd(2+) in aqueous solution was slightly enhanced after modification, indicating that Cd(2+) adsorption on BS-Mt was mainly attributed to direct electrostatic attraction and the chelate reaction, while the dramatic enhancement of maximum adsorption capacity for BPA was due to the hydrophobic interaction. PMID:26451652

  9. Bisphenol A (BPA) in food contact materials - new scientific opinion from EFSA regarding public health risk.

    PubMed

    Ćwiek-Ludwicka, Kazimiera

    2015-01-01

    The wide use of bisphenol A (BPA) as a monomer in plastics manufacture or epoxy resins intended for food contact materials (FCM) has triggered numerous concerns due to toxicological findings indicating possible endocrine disrupting properties. This article traces the evolution of the scientific opinions since 1986 when the Tolerable Daily Intake (TDI) for BPA and its specific migration limit (SML) from plastic FCM into food were proposed for the first time by the Scientific Committee for Food (SCF). Resent extensive scientific studies concerning refined data on toxicity and exposure to BPA from food and non-food sources (eg. dust, cosmetics, thermal paper), including the most vulnerable groups of population, allowed the European Food Safety Authority (EFSA) to reduce the TDI of BPA from previously 50 µg/kg bw/day to now 4 µg/kg bw/day. EFSA's latest scientific opinion published in 2015 concludes that basing on the current estimations of total exposure to BPA from dietary and non-dietary sources for infants, children and adolescents is below the temporary TDI of 4 μg/kg bw/day. EFSA has also underlined that BPA poses no health risk at the estimated exposure levels of any population age group, including unborn children and the elderly. However, EFSA has indicated that some data on exposure and toxicological effects still require clarifications.

  10. Certification of Financial Aid Administrators

    ERIC Educational Resources Information Center

    Peterson, Stacey A.

    2011-01-01

    The certification of financial aid administrators has been debated for over 37 years. A job satisfaction survey conducted by the National Association of Student Financial Aid Administrators (NASFAA, 2008a) revealed that college and university administrators' perceptions of the efficiency, effectiveness, and quality of the services provided by the…

  11. Developmental programming: Prenatal BPA treatment disrupts timing of LH surge and ovarian follicular wave dynamics in adult sheep

    SciTech Connect

    Veiga-Lopez, A.; Beckett, E.M.; Abi Salloum, B.; Ye, W.; Padmanabhan, V.

    2014-09-01

    Developmental exposure to BPA adversely affects reproductive function. In sheep, prenatal BPA treatment induces reproductive neuroendocrine defects, manifested as LH excess and dampened LH surge and perturbs early ovarian gene expression. In this study we hypothesized that prenatal BPA treatment will also disrupt ovarian follicular dynamics. Pregnant sheep were treated from days 30 to 90 of gestation with 3 different BPA doses (0.05, 0.5, or 5 mg/kg BW/day). All female offspring were estrus synchronized and transrectal ultrasonography was performed daily for 22 days to monitor ovarian follicular and corpora lutea dynamics. Blood samples were collected to assess preovulatory hormonal changes and luteal progesterone dynamics. Statistical analysis revealed that the time interval between the estradiol rise and the preovulatory LH surge was shortened in the BPA-treated females. None of the three BPA doses had an effect on corpora lutea, progestogenic cycles, and mean number or duration of ovulatory and non-ovulatory follicles. However, differences in follicular count trajectories were evident in all three follicular size classes (2–3 mm, 4–5 mm, and ≥ 6 mm) of prenatal BPA-treated animals compared to controls. Number of follicular waves tended also to be more variable in the prenatal BPA-treated groups ranging from 2 to 5 follicular waves per cycle, while this was restricted to 3 to 4 waves in control females. These changes in ovarian follicular dynamics coupled with defects in time interval between estradiol rise and preovulatory LH release are likely to lead to subfertility in prenatal BPA-treated females. - Highlights: • Prenatal BPA shortens interval between estradiol rise and preovulatory LH surge. • Prenatal BPA affects follicular count trajectory and follicular wave occurrence. • Prenatal BPA does not affect ovulatory rate and progesterone dynamics.

  12. Effects of developmental exposure to bisphenol A on spatial navigational learning and memory in rats: A CLARITY-BPA study.

    PubMed

    Johnson, Sarah A; Javurek, Angela B; Painter, Michele S; Ellersieck, Mark R; Welsh, Thomas H; Camacho, Luísa; Lewis, Sherry M; Vanlandingham, Michelle M; Ferguson, Sherry A; Rosenfeld, Cheryl S

    2016-04-01

    Bisphenol A (BPA) is a ubiquitous industrial chemical used in the production of a wide variety of items. Previous studies suggest BPA exposure may result in neuro-disruptive effects; however, data are inconsistent across animal and human studies. As part of the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA), we sought to determine whether female and male rats developmentally exposed to BPA demonstrated later spatial navigational learning and memory deficits. Pregnant NCTR Sprague-Dawley rats were orally dosed from gestational day 6 to parturition, and offspring were directly orally dosed until weaning (postnatal day 21). Treatment groups included a vehicle control, three BPA doses (2.5μg/kg body weight (bw)/day-[2.5], 25μg/kg bw/day-[25], and 2500μg/kg bw/day-[2500]) and a 0.5μg/kg/day ethinyl estradiol (EE)-reference estrogen dose. At adulthood, 1/sex/litter was tested for seven days in the Barnes maze. The 2500 BPA group sniffed more incorrect holes on day 7 than those in the control, 2.5 BPA, and EE groups. The 2500 BPA females were less likely than control females to locate the escape box in the allotted time (p value=0.04). Although 2.5 BPA females exhibited a prolonged latency, the effect did not reach significance (p value=0.06), whereas 2.5 BPA males showed improved latency compared to control males (p value=0.04), although the significance of this result is uncertain. No differences in serum testosterone concentration were detected in any male or female treatment groups. Current findings suggest developmental exposure of rats to BPA may disrupt aspects of spatial navigational learning and memory.

  13. Perinatal BPA exposure induces hyperglycemia, oxidative stress and decreased adiponectin production in later life of male rat offspring.

    PubMed

    Song, Shunzhe; Zhang, Ling; Zhang, Hongyuan; Wei, Wei; Jia, Lihong

    2014-04-01

    The main object of the present study was to explore the effect of perinatal bisphenol A (BPA) exposure on glucose metabolism in early and later life of male rat offspring, and to establish the potential mechanism of BPA-induced dysglycemia. Pregnant rats were treated with either vehicle or BPA by drinking water at concentrations of 1 and 10 µg/mL BPA from gestation day 6 through the end of lactation. We measured the levels of fasting serum glucose, insulin, adiponectin and parameters of oxidative stress on postnatal day (PND) 50 and PND100 in male offspring, and adiponectin mRNA and protein expression in adipose tissue were also examined. Our results showed that perinatal exposure to 1 or 10 µg/mL BPA induced hyperglycemia with insulin resistance on PND100, but only 10 µg/mL BPA exposure had similar effects as early as PND50. In addition, increased oxidative stress and decreased adiponectin production were also observed in BPA exposed male offspring. Our findings indicated that perinatal exposure to BPA resulted in abnormal glucose metabolism in later life of male offspring, with an earlier and more exacerbated effect at higher doses. Down-regulated expression of adiponectin gene and increased oxidative stress induced by BPA may be associated with insulin resistance.

  14. Effect of BPA on the germination, root development, seedling growth and leaf differentiation under different light conditions in Arabidopsis thaliana.

    PubMed

    Pan, Wen-Juan; Xiong, Can; Wua, Qiu-Ping; Liu, Jin-Xia; Liao, Hong-Mei; Chen, Wei; Liu, Yong-Sheng; Zheng, Lei

    2013-11-01

    Bisphenol A (BPA) is a well-known environmental toxic substance, which exerts unfavorable effects through endocrine disruptor (ER)-dependent and ER-independent mechanisms to threaten ecological systems seriously. BPA may also interact with other environmental factors, such as light and heavy metals, to have a synergetic effect in plants. However, there is little data concerning the toxic effect of BPA on the primary producers-plants and its possible interaction with light-dependent response. Here, the effects of BPA on germination, fresh weight, tap root length, and leaf differentiation were studied in Arabidopsis thaliana under different parts of light spectrum (dark, red, yellow, green, blue, and white light). Our results showed that low-dose BPA (1.0, 5.0 µM) caused an increase in the fresh weight, the tap root length and the lateral root formation of A. thaliana seedlings, while high-dose BPA (10.0, 25.0 µM) show an inhibition effect in a dose-dependent manner. Unlike karrikins, the effects of BPA on germination fresh weight and tap roots length under various light conditions are similar, which imply that BPA has no notable role in priming light response in germination and early seedling growth in A. thaliana. Meanwhile, BPA exposure influences the differentiation of A. thaliana leaf blade significantly in a light-dependent manner with little to no effect in dark and clear effect under red illumination.

  15. Bisphenol A (BPA) Found in Humans and Water in Three Geographic Regions with Distinctly Different Levels of Economic Development

    PubMed Central

    Karalius, Vytas P.; Harbison, Justin E.; Plange-Rhule, Jacob; van Breemen, Richard B.; Li, Guannan; Huang, Ke; Durazo-Arvizu, Ramon A.; Mora, Nallely; Dugas, Lara R.; Vail, Lane; Tuchman, Nancy C.; Forrester, Terrence; Luke, Amy

    2014-01-01

    The suspected endocrine disruptor bisphenol A (BPA) is associated with the manufacture, distribution, and use of epoxy resins and polycarbonate plastics; thus, studies of this compound have focused primarily on urban areas in developed countries. This small study investigating urinary BPA of 109 people was conducted in the urban United States, urban Jamaica, and rural Ghana. Additionally, local drinking and surface water samples were collected and analyzed from areas near study participants. Levels of BPA in both urine and water were comparable among all three sites. Thus, future studies of BPA should consider expanding investigations to rural areas not typically associated with the compound. PMID:24453495

  16. The Genotoxic and Cytotoxic Effects of Bisphenol-A (BPA) in MCF-7 Cell Line and Amniocytes

    PubMed Central

    Aghajanpour-Mir, Seyed Mohsen; Zabihi, Ebrahim; Akhavan-Niaki, Haleh; Keyhani, Elahe; Bagherizadeh, Iman; Biglari, Sajjad; Behjati, Farkhondeh

    2016-01-01

    Bisphenol-A (BPA) is an industrial xenoestrogen used widely in our living environment. Recently, several studies suggested that BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. However, there are still many controversial issues which need clarification. In this study, we investigated the BPA-induced chromosomal damages in MCF-7 cell line, ER-positive and negative amniocyte cells. Cytotoxicity and genotoxicity effects of BPA were also compared between these three cell groups. Expression of estrogen receptors was determined using immunocytochemistry technique. The cell cytotoxicity of BPA was measured by MTT assay. Classic cytogenetic technique was carried out for the investigation of chromosome damage. BPA, in addition to cytotoxicity, had remarkable genotoxicity at concentrations close to the traceable levels in tissues or biological fluids. Although some differences were observed in the amount of damages between ER-positive and negative fetal cells, interestingly, these differences were not significant. The present study showed that BPA could lead to chromosomal aberrations in both ER-dependent and independent pathways at some concentrations or in cell types yet not reported. Also, BPA could probably be considered as a facilitator for some predisposed cells to be cancerous by raising the chromosome instability levels. Finally, estrogen receptor seems to have a different role in cytotoxicity and genotoxicity effects. PMID:27386435

  17. The Genotoxic and Cytotoxic Effects of Bisphenol-A (BPA) in MCF-7 Cell Line and Amniocytes.

    PubMed

    Aghajanpour-Mir, Seyed Mohsen; Zabihi, Ebrahim; Akhavan-Niaki, Haleh; Keyhani, Elahe; Bagherizadeh, Iman; Biglari, Sajjad; Behjati, Farkhondeh

    2016-01-01

    Bisphenol-A (BPA) is an industrial xenoestrogen used widely in our living environment. Recently, several studies suggested that BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. However, there are still many controversial issues which need clarification. In this study, we investigated the BPA-induced chromosomal damages in MCF-7 cell line, ER-positive and negative amniocyte cells. Cytotoxicity and genotoxicity effects of BPA were also compared between these three cell groups. Expression of estrogen receptors was determined using immunocytochemistry technique. The cell cytotoxicity of BPA was measured by MTT assay. Classic cytogenetic technique was carried out for the investigation of chromosome damage. BPA, in addition to cytotoxicity, had remarkable genotoxicity at concentrations close to the traceable levels in tissues or biological fluids. Although some differences were observed in the amount of damages between ER-positive and negative fetal cells, interestingly, these differences were not significant. The present study showed that BPA could lead to chromosomal aberrations in both ER-dependent and independent pathways at some concentrations or in cell types yet not reported. Also, BPA could probably be considered as a facilitator for some predisposed cells to be cancerous by raising the chromosome instability levels. Finally, estrogen receptor seems to have a different role in cytotoxicity and genotoxicity effects. PMID:27386435

  18. The Genotoxic and Cytotoxic Effects of Bisphenol-A (BPA) in MCF-7 Cell Line and Amniocytes.

    PubMed

    Aghajanpour-Mir, Seyed Mohsen; Zabihi, Ebrahim; Akhavan-Niaki, Haleh; Keyhani, Elahe; Bagherizadeh, Iman; Biglari, Sajjad; Behjati, Farkhondeh

    2016-01-01

    Bisphenol-A (BPA) is an industrial xenoestrogen used widely in our living environment. Recently, several studies suggested that BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. However, there are still many controversial issues which need clarification. In this study, we investigated the BPA-induced chromosomal damages in MCF-7 cell line, ER-positive and negative amniocyte cells. Cytotoxicity and genotoxicity effects of BPA were also compared between these three cell groups. Expression of estrogen receptors was determined using immunocytochemistry technique. The cell cytotoxicity of BPA was measured by MTT assay. Classic cytogenetic technique was carried out for the investigation of chromosome damage. BPA, in addition to cytotoxicity, had remarkable genotoxicity at concentrations close to the traceable levels in tissues or biological fluids. Although some differences were observed in the amount of damages between ER-positive and negative fetal cells, interestingly, these differences were not significant. The present study showed that BPA could lead to chromosomal aberrations in both ER-dependent and independent pathways at some concentrations or in cell types yet not reported. Also, BPA could probably be considered as a facilitator for some predisposed cells to be cancerous by raising the chromosome instability levels. Finally, estrogen receptor seems to have a different role in cytotoxicity and genotoxicity effects.

  19. 45 CFR 74.47 - Contract administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Contract administration. 74.47 Section 74.47 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION UNIFORM ADMINISTRATIVE... administration. A system for contract administration shall be maintained to ensure contractor conformance...

  20. 5 CFR 831.101 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Administration. 831.101 Section 831.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.101 Administration. (a) OPM has charge of...

  1. Administrative Synergy

    ERIC Educational Resources Information Center

    Hewitt, Kimberly Kappler; Weckstein, Daniel K.

    2012-01-01

    One of the biggest obstacles to overcome in creating and sustaining an administrative professional learning community (PLC) is time. Administrators are constantly deluged by the tyranny of the urgent. It is a Herculean task to carve out time for PLCs, but it is imperative to do so. In this article, the authors describe how an administrative PLC…

  2. Conjugated Bisphenol A (BPA) in maternal serum in relation to miscarriage risk

    PubMed Central

    Lathi, Ruth B.; Liebert, Cara A.; Brookfield, Kathleen F.; Taylor, Julia A.; Saal, Frederick S. vom; Fujimoto, Victor Y.; Baker, Valerie L.

    2014-01-01

    Objective To examine the relationship between maternal serum Bisphenol-A (BPA) concentration at the time of the missed period and miscarriage risk. Design Retrospective cohort of prospectively collected serum samples. Setting Academic fertility center. Patients Women presenting for early pregnancy monitoring with singleton pregnancies. Intervention Stored serum samples from 4-5 weeks gestation were analyzed for conjugated serum BPA concentrations. Main Outcomes Live birth, miscarriage, and chromosome content of miscarriage. Results Of the 115 included subjects, there were 47 live births and 68 clinical miscarriages (46 aneuploid and 22 euploid). Median conjugated BPA concentrations were higher in women with miscarriages than those with live births (0.101 vs 0.075 ng/ml). Women with the highest quartile of conjugated BPA had an increased relative risk of miscarriage (1.83, 95% CI 1.14-2.96) compared to women in the lowest quartile. We found a similar increase risk for both euploid and aneuploid miscarriages. Conclusions Maternal conjugated BPA was associated with higher risk of aneuploid and euploid miscarriage in this cohort. The impact of reducing individual exposures on future pregnancy outcomes deserves further study. PMID:24746738

  3. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ... Employment and Training Administration Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service...-Tech Customer Service, Philadelphia, Pennsylvania and Verizon Business Networks Services,...

  4. Discretionary Grants Administration Manual.

    ERIC Educational Resources Information Center

    Office of Human Development Services (DHHS), Washington, DC.

    This manual sets forth applicable administrative policies and procedures to recipients of discretionary project grants or cooperative agreements awarded by program offices in the Office of Human Development Services (HDS). It is intended to serve as a basic reference for project directors and business officers of recipient organizations who are…

  5. Migrant Education Administrative Handbook.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Bureau of Migrant Education.

    Intended to provide information pertaining to the administration of migrant education projects in Louisiana, the handbook is divided into two sections: basic guidelines for program operations and support services--nursing. Section I covers the Federal and State migrant program, local migrant projects, project personnel and staff development, and…

  6. State of Rhode Island Department of Administration Office of Library and Information Services. Five-Year State Plan for the Fiscal Years 2008 to 2012

    ERIC Educational Resources Information Center

    Rhode Island Office of Library and Information Services, 2008

    2008-01-01

    In preparation for its Five-Year Plan for the years 2008 through 2012, the Rhode Island Office of Library and Information Services has reviewed a variety of information resources, including studies, publications, surveys and stakeholder meetings, to assist in understanding the state, its people, its future and the potential role of libraries. This…

  7. Learning from the Partnership Literature: Implications for UK University/National Health Service Relationships and for Research Administrators Supporting Applied Health Research

    ERIC Educational Resources Information Center

    Perkins, Mary; Bauld, Linda; Langley, David

    2010-01-01

    The Department of Health in England released a new health research strategy in 2006 with far-reaching implications for both health research and research management. The explicit policy shift is towards centres of excellence and away from historical block allocations of funding to National Health Service (NHS) healthcare organisations--with these…

  8. High intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity.

    PubMed

    Branco, Alan T; Lemos, Bernardo

    2014-05-01

    Bisphenol A (BPA) is an organic compound to which human populations are ubiquitously exposed. Epidemiological data suggest BPA exposure might be associated with higher rates of diabetes and reproductive anomalies. Health concerns also include transgenerational consequences, but these mechanisms are crudely defined. Similarly, little is known about synergistic interactions between BPA and other substances. Here we show that acute and chronic exposure to BPA causes genome-wide modulation of several functionally coherent genetic pathways in the fruit fly Drosophila melanogaster. In particular, BPA exposure causes massive downregulation of testis-specific genes and upregulation of ribosome-associated genes widely expressed across tissues. In addition, it causes the modulation of transposable elements that are specific to the ribosomal DNA loci, suggesting that nucleolar stress might contribute to BPA toxicity. The upregulation of ribosome-associated genes and the impairment of testis-specific gene expression are significantly enhanced upon BPA exposure with a high-sugar diet. Our results suggest that BPA and dietary sugar might functionally interact, with consequences to regulatory programs in both reproductive and somatic tissues.

  9. BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats.

    PubMed

    Jiang, Ying; Xia, Wei; Yang, Jie; Zhu, Yingshuang; Chang, Huailong; Liu, Juan; Huo, Wenqian; Xu, Bing; Chen, Xi; Li, Yuanyuan; Xu, Shunqing

    2015-03-01

    Implication of environmental endocrine disruptors, such as bisphenol A (BPA), on the development of cardiopathy has been poorly investigated. The aim of the study was to investigate the effects of long-term exposure to BPA at the reference dose on the myocardium of rats, and the underlying mechanisms. Male rats received corn oil or 50 μg/kg/day of BPA since delactation. At 24 and 48 weeks (wk), cardiac function and mitochondrial function were examined. The mRNA expression and the methylation status of PCG-1α, a major regulator of mitochondrial biogenesis in cardiac muscle, were also tested. At 48 wk, BPA-exposed rats displayed cardiomyopathy, characterized by myocardium hypertrophy, cardiomyocyte enlargement, and impairment of cardiac function. At 24 wk, significantly reduced ATP production, dissipated mitochondrial membrane potential (Ψm) and declined mitochondrial respiratory complex (MRC) activity in cardiomyocytes were observed in BPA-exposed rats compared with the control rats, indicating a decrease in mitochondrial function occurs before the development of cardiomyopathy. Additionally, BPA exposure decreased the expression of PGC-1α and induced hypermethylation of PGC-1 α in heart tissue in 24- and 48-week-old rats. The change in methylation of PGC-1α was observed more pronounced in BPA-exposed rats at 48 wk. Overall, long-term BPA exposure induces cardiomyopathy in male rats, and the underlying mechanism may involve the impairment of cardiac mitochondrial function and the disturbance of methylation of PGC-1α.

  10. 7 CFR 1205.11 - Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Procedures for Conduct of Sign-up Period Definitions § 1205.11 Administrator. The term Administrator means the Administrator of the Agricultural Marketing Service, or any officer or employee of USDA to...

  11. 7 CFR 23.2 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Administration. (a) Title V will be administered by the Administrators of the Extension Service and the Cooperative State Research Service for extension and research programs respectively, in cooperation with the chief administrative officer of the State Land Grant University who will administer the program...

  12. 50 CFR 401.1 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Administration. 401.1 Section 401.1... INTERIOR AND NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT..., DEVELOPMENT AND ENHANCEMENT § 401.1 Administration. The Director of the U.S. Fish and Wildlife Service and...

  13. 28 CFR 802.16 - Administrative appeal.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Administrative appeal. 802.16 Section 802.16 Judicial Administration COURT SERVICES AND OFFENDER SUPERVISION AGENCY FOR THE DISTRICT OF... of appeal should be sent to the Office of the General Counsel, Court Services and...

  14. 28 CFR 802.16 - Administrative appeal.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Administrative appeal. 802.16 Section 802.16 Judicial Administration COURT SERVICES AND OFFENDER SUPERVISION AGENCY FOR THE DISTRICT OF... of appeal should be sent to the Office of the General Counsel, Court Services and...

  15. 5 CFR 362.301 - Program administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Program administration. 362.301 Section 362.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS... an entry-level developmental experience designed to lead to a civil service career in the...

  16. 5 CFR 362.301 - Program administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Program administration. 362.301 Section 362.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS... an entry-level developmental experience designed to lead to a civil service career in the...

  17. American Recovery and Reinvestment Act (ARRA) FEMP Technical Assistance U.S. General Services Administration – Project 195 John Seiberling Federal Office Building and U.S. Courthouse, Akron, Ohio

    SciTech Connect

    Arends, J.; Sandusky, William F.

    2010-05-28

    This report documents the findings from an onsite audit of the John Seiberling Federal building located in Akron, Ohio. The Federal landlord for this building is the General Services Administration (GSA). The focus of the audit was to identify various no-cost or low-cost energy efficiency opportunities that, once implemented, would reduce in either electrical and gas consumption and increase the operational efficiency of the building. This audit also provided an opportunity to identify potential capital cost projects that should be considered in the to acquire additional energy (electric and gas) and water savings to further increase the operational efficiency of the building.

  18. Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells.

    PubMed

    Yin, Nuoya; Yao, Xinglei; Qin, Zhanfen; Wang, Yuan-Liang; Faiola, Francesco

    2015-10-01

    The adverse effects of environmental pollution on our well-being have been intensively studied with many in vitro and in vivo systems. In our group, we focus on stem cell toxicology due to the multitude of embryonic stem cell (ESC) properties which can be exerted in toxicity assays. In fact, ESCs can differentiate in culture to mimic embryonic development in vivo, or specifically to virtually any kind of somatic cells. Here, we used the toxicant Bisphenol A (BPA), a chemical known as a hazard to infants and children, and showed that our stem cell toxicology system was able to efficiently recapitulate most of the toxic effects of BPA previously detected by in vitro system or animal tests. More precisely, we demonstrated that BPA affected the proper specification of germ layers during our in vitro mimicking of the embryonic development, as well as the establishment of neural ectoderm and neural progenitor cells. PMID:26456621

  19. Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells.

    PubMed

    Yin, Nuoya; Yao, Xinglei; Qin, Zhanfen; Wang, Yuan-Liang; Faiola, Francesco

    2015-10-01

    The adverse effects of environmental pollution on our well-being have been intensively studied with many in vitro and in vivo systems. In our group, we focus on stem cell toxicology due to the multitude of embryonic stem cell (ESC) properties which can be exerted in toxicity assays. In fact, ESCs can differentiate in culture to mimic embryonic development in vivo, or specifically to virtually any kind of somatic cells. Here, we used the toxicant Bisphenol A (BPA), a chemical known as a hazard to infants and children, and showed that our stem cell toxicology system was able to efficiently recapitulate most of the toxic effects of BPA previously detected by in vitro system or animal tests. More precisely, we demonstrated that BPA affected the proper specification of germ layers during our in vitro mimicking of the embryonic development, as well as the establishment of neural ectoderm and neural progenitor cells.

  20. Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study.

    PubMed

    Bergenheim, A Tommy; Capala, Jacek; Roslin, Michael; Henriksson, Roger

    2005-02-01

    Boron neutron capture therapy (BNCT) is dependent on the selective accumulation of boron-10 in tumour cells. To maximise the radiation effect, the neutrons should be delivered when the ratio between the boron concentration in tumour cells to that in normal tissues reaches maximum. However, the pharmacokinetics of p-boronophenylalanine (BPA) and other boron delivery agents are only partly known. We used microdialysis to investigate the extracellular in vivo kinetics of boron in three intracerebral compartments -- solid tumour, brain adjacent to tumour (BAT), and the normal brain, as well as the subcutaneous tissue before, during, and after BNCT treatment. The findings were compared to the pharmacokinetics of BPA in the blood. We also measured the glucose metabolism and the levels of glutamate and glycerol in those compartments. Four patients were studied, two patients underwent surgical tumour resection and in two a stereotactic biopsy was performed. The patients were given BPA (900 mg/kg body weight) by a 6-h infusion. The infusion was completed approximately 2-3 h before neutron irradiation. In tumour tissue the extracellular concentration of BPA followed that of blood with a maximal concentration of 31.2 ppm and a maximal ratio vs. blood of 1.07. In BAT, the maximal concentration of BPA was 18.0 ppm with the peak level delayed for 4-6 h compared to the peak in blood with a maximal ratio of 1.2. Maximal blood concentration found was 41.0 ppm. The uptake of BPA in the normal brain was considerably lower than that in the blood and tumour tissue. No change in glucose metabolism was observed. The extracellular level of glycerol was increased after treatment in tumour tissue but not in normal brain suggesting a selective acute cytotoxic effect of BNCT on tumour cells. PMID:15735919

  1. Demonstration Assessment of Light-Emitting Diode (LED) Retrofit Lamps at the Lobby of the Bonneville Power Administration, Portland, OR

    SciTech Connect

    Miller, Naomi

    2011-07-01

    This report describes the process and results of a demonstration of solid-state lighting (SSL) technology in the lobby of the Bonneville Power Administration (BPA) headquarters building in Portland, Oregon. The project involved a simple retrofit of 32 track lights used to illuminate historical black-and-white photos and printed color posters from the 1930s and 1940s. BPA is a federal power marketing agency in the Northwestern United States, and selected this prominent location to demonstrate energy efficient light-emitting diode (LED) retrofit options that not only can reduce the electric bill for their customers but also provide attractive alternatives to conventional products, in this case accent lighting for BPA's historical artwork.

  2. 7 CFR 1580.501 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Administration. 1580.501 Section 1580.501 Agriculture Regulations of the Department of Agriculture (Continued) FOREIGN AGRICULTURAL SERVICE, DEPARTMENT OF... assistance and services to a state cooperative extension service. (e) The Deputy Administrator may,...

  3. Administrative Ecology

    ERIC Educational Resources Information Center

    McGarity, Augustus C., III; Maulding, Wanda

    2007-01-01

    This article discusses how all four facets of administrative ecology help dispel the claims about the "impossibility" of the superintendency. These are personal ecology, professional ecology, organizational ecology, and community ecology. Using today's superintendency as an administrative platform, current literature describes a preponderance of…

  4. Administrative Support.

    ERIC Educational Resources Information Center

    Doran, Dorothy; And Others

    This guide is intended to assist business education teachers in administrative support courses. The materials presented are based on the Arizona validated occupational competencies and tasks for the occupations of receptionist, secretary, and administrative assistant. Word processing skills have been infused into each of the three sections. The…

  5. Comparison of the effects of BPA and BPAF on oocyte spindle assembly and polar body release in mice.

    PubMed

    Nakano, Kei; Nishio, Manami; Kobayashi, Norio; Hiradate, Yuuki; Hoshino, Yumi; Sato, Eimei; Tanemura, Kentaro

    2016-04-01

    Bisphenol AF (BPAF), a homolog of bisphenol A (BPA), is a widely used environmental chemical that has adverse effects on reproduction. The aim of this study was to analyse the effects of BPA and BPAF exposure on oocyte maturation in vitro. Oocytes were cultured in the presence of BPA or BPAF (2, 20, 50 or 100 μg/ml) for 18 h. At concentrations of 50 and 100 μg/ml, BPA and BPAF inhibited oocyte maturation, with BPAF treatment causing a sharp decrease in the number of oocytes reaching maturity. Oocytes were exposed to BPA or BPAF at 2 μg/ml and cultured for different durations (6, 9, 12, 15 or 18 h). Both BPAF and BPA caused a cell cycle delay under these conditions. Oocytes cultured in the presence of BPA or BPAF (50 μg/ml) for 21 h were tested for the localization of α-tubulin and MAD2 using immunofluorescence. High concentrations of BPAF induced cell cycle arrest through the activation of the spindle assembly checkpoint. After 12 h of culture in BPAF (50 μg/ml), oocytes were transferred to control medium for 9 h. Only 63.3% oocytes treated in this manner progressed to metaphase II (MII). Oocytes exposed to high doses of BPA experienced a cell cycle delay, but managed to progress to MII when the culture period was prolonged. In addition, MAD2 was localized in the cytoplasm of these oocytes. In conclusion, both BPAF and BPA exposure affected oocyte maturation, however BPAF and BPA have differential effects on SAC activity.

  6. 41 CFR 105-53.130 - Office of the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administrator. 105-53.130 Section 105-53.130 Public Contracts and Property Management Federal Property... FUNCTIONS Central Offices § 105-53.130 Office of the Administrator. The Administrator of General Services... assigned to the General Services Administration. The Deputy Administrator, who is appointed by...

  7. Environmental audit, Bonneville Power Administration, lower Columbia area

    SciTech Connect

    Not Available

    1990-11-01

    This report documents the results of the US Department of Energy's (DOE's) Environmental Audit conducted by the DOE Headquarters Office of Environmental Audit within the Bonneville Power Administration's (BPA's) Lower Columbia Area. The BPA facilities included in the Audit are the Ross Complex in Vancouver, Washington; the substations of North Bonneville, North Bonneville Annex, Camas, and Longview within the state of Washington; and the Acton and Troutdale Substations within the state of Oregon. The independent Audit was conducted by a team of professionals from DOE and contractors. The purpose of the Audit is to provide the Secretary of Energy, Admiral James D. Watkins, Ret., with the status of environmental programs within BPA's Lower Columbia Area. The Environmental Audit team identified 25 findings dealing with the lack of conformance with federal and state laws and regulations and DOE Orders, and 7 findings in which BMPs were not attained. Although all findings require corrective action, none required cessation of operations or reflect situations that present an immediate risk to public health or the environment. The Audit team noted inadequacies in PCB management included storage, labeling, reporting, and spill control. The most significant causal factors for the findings include lack of policy implementation throughout the Lower Columbia Area, inadequate training of personnel charged with environmental protection, lack of standard operating procedures for many programs, lack of reviews and appraisals, and an inaccurate perception of low risk for environmental concerns.

  8. 1993 status report - The Bonneville Power Administration's geothermal program

    SciTech Connect

    Darr, G.D. )

    1993-01-01

    The Bonneville Power Administration's (BPA) Geothermal Program includes up to three demonstration (pilot) power projects that will initiate development of high-potential reservoirs in the Pacific Northwest. The program also includes activities that support the pilot projects and that encourage the use of the region's geothermal resources. Activities supporting the pilot projects include initiating environmental baseline monitoring programs and conducting environmental and economic impact studies. Research activities include efforts to better understand the cold water blanket phenomenon in the Cascades, a study to characterize the hydrothermal system in the Pueblo Valley, a geothermal exploration program in southeastern Oregon, and support for research to expand the use of slim-holes for resource confirmation. Efforts to address institutional issues include support for the Regional Renewables Project, which will help Northwest environmentalists become more knowledgeable about the role of conservation and renewables in the region's energy picture. A guide to geothermal permitting and licensing was prepared to help developers and utilities find their way through the regulatory maze. A geothermal curriculum is being developed for grades 4 through 8 in the Oregon schools. Data on the location and operating experience of existing U.S. geothermal plants has been collected in a database. Market penetration of geothermal heat pumps is being encouraged through a demonstration project in Montana and by helping BPA customers prepare proposals for geothermal heat pump projects that can compete successfully in BPA power acquisitions.

  9. Rehabilitation and the Veterans' Administration

    NASA Technical Reports Server (NTRS)

    Meister, F.

    1974-01-01

    The Veteran's Administration health care system provides prosthetic and sensory aids for the rehabilitation of neurologically handicapped veterans. Research and development centers include prosthetic clinic teams, orthopedic shops, restoration clinics, bioengineering services, orthotics, etc.

  10. 76 FR 80329 - Information Collection; Grazing Permit Administration Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Forest Service Information Collection; Grazing Permit Administration Forms AGENCY: Forest Service, USDA... Forest Service is seeking comments from all interested individuals and organizations on the extension...: Comments concerning this notice should be addressed to: USDA, Forest Service, Attn: Director,...

  11. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., including such services as general legal services, accounting services, and audit services; and (4) Other...-specific environmental review costs may be charged as administrative costs or as project costs, at...

  12. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., including such services as general legal services, accounting services, and audit services; and (4) Other...-specific environmental review costs may be charged as administrative costs or as project costs, at...

  13. 5 CFR 362.101 - Program administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Program administration. 362.101 Section 362.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS PROGRAMS General Provisions § 362.101 Program administration. (a) The Pathways Programs authorized under Executive Order 13562 consist of the...

  14. 7 CFR 1230.603 - Administrator, FSA.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Administrator, FSA. 1230.603 Section 1230.603... CONSUMER INFORMATION Procedures for the Conduct of Referendum Definitions § 1230.603 Administrator, FSA. The term Administrator, FSA, means the Administrator, of the Farm Service Agency, or any officer...

  15. 7 CFR 1280.603 - Administrator, FSA.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Administrator, FSA. 1280.603 Section 1280.603... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.603 Administrator, FSA. Administrator, FSA, means the Administrator, of the Farm Service Agency, or any officer or employee of USDA to...

  16. 7 CFR 1280.602 - Administrator, AMS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Administrator, AMS. 1280.602 Section 1280.602... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.602 Administrator, AMS. Administrator, AMS, means the Administrator of the Agricultural Marketing Service, or any officer or employee of...

  17. 7 CFR 1230.602 - Administrator, AMS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Administrator, AMS. 1230.602 Section 1230.602... CONSUMER INFORMATION Procedures for the Conduct of Referendum Definitions § 1230.602 Administrator, AMS. The term Administrator, AMS, means the Administrator of the Agricultural Marketing Service, or...

  18. 7 CFR 29.9231 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Administration. 29.9231 Section 29.9231 Agriculture... Tobacco Produced and Marketed in a Quota Area Administration § 29.9231 Administration. The Director... the administration of the act. The conduct of all services and the licensing or employment...

  19. BPA-Induced Deregulation Of Epigenetic Patterns: Effects On Female Zebrafish Reproduction.

    PubMed

    Santangeli, Stefania; Maradonna, Francesca; Gioacchini, Giorgia; Cobellis, Gilda; Piccinetti, Chiara Carla; Dalla Valle, Luisa; Carnevali, Oliana

    2016-01-01

    Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms. To determine its effects on female reproductive physiology and investigate whether changes in the expression levels of genes related to reproduction are caused by histone modifications, BPA concentrations consistent with environmental exposure were administered to zebrafish for three weeks. Effects on oocyte growth and maturation, autophagy and apoptosis processes, histone modifications, and DNA methylation were assessed by Real-Time PCR (qPCR), histology, and chromatin immunoprecipitation combined with qPCR analysis (ChIP-qPCR). The results showed that 5 μg/L BPA down-regulated oocyte maturation-promoting signals, likely through changes in the chromatin structure mediated by histone modifications, and promoted apoptosis in mature follicles. These data indicate that the negative effects of BPA on the female reproductive system may be due to its upstream ability to deregulate epigenetic mechanism.

  20. BPA-Induced Deregulation Of Epigenetic Patterns: Effects On Female Zebrafish Reproduction.

    PubMed

    Santangeli, Stefania; Maradonna, Francesca; Gioacchini, Giorgia; Cobellis, Gilda; Piccinetti, Chiara Carla; Dalla Valle, Luisa; Carnevali, Oliana

    2016-01-01

    Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms. To determine its effects on female reproductive physiology and investigate whether changes in the expression levels of genes related to reproduction are caused by histone modifications, BPA concentrations consistent with environmental exposure were administered to zebrafish for three weeks. Effects on oocyte growth and maturation, autophagy and apoptosis processes, histone modifications, and DNA methylation were assessed by Real-Time PCR (qPCR), histology, and chromatin immunoprecipitation combined with qPCR analysis (ChIP-qPCR). The results showed that 5 μg/L BPA down-regulated oocyte maturation-promoting signals, likely through changes in the chromatin structure mediated by histone modifications, and promoted apoptosis in mature follicles. These data indicate that the negative effects of BPA on the female reproductive system may be due to its upstream ability to deregulate epigenetic mechanism. PMID:26911650