78 FR 40382 - Modification of Class D and E Airspace; Twin Falls, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

...-0258; Airspace Docket No. 13-ANM-12] Modification of Class D and E Airspace; Twin Falls, ID AGENCY... Class D airspace, omitted from the Title in the notice of proposed rulemaking is included in this rule... were received. Subsequent to publication, the FAA found that the Class D airspace reference was omitted...

15 CFR 904.201 - Hearing requests and case docketing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures General § 904.201 Hearing requests and case docketing. (a) If the...

15 CFR 904.201 - Hearing requests and case docketing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures General § 904.201 Hearing requests and case docketing. (a) If the...

49 CFR 601.44 - Posting to the docket.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Posting to the docket. 601.44 Section 601.44 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for Public...

Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuous stress.

PubMed

Konishi, H; Ogawa, T; Nakagomi, S; Inoue, K; Tohyama, M; Kiyama, H

2010-09-15

In rats under continuous stress (CS) there is decreased hypothalamic dopaminergic innervation to the intermediate lobe (IL) of the pituitary gland, which causes hyperactivation and subsequent degeneration of melanotrophs in the IL. In this study, we investigated the molecular basis for the changes that occur in melanotrophs during CS. Using microarray analysis, we identified several genes differentially expressed in the IL under CS conditions. Among the genes up-regulated under CS conditions, we focused on the inhibitor of DNA binding/differentiation (Id) family of dominant negative basic helix-loop-helix (bHLH) transcription factors. RT-PCR, Western blotting and in situ hybridization confirmed the significant inductions of Id1, Id2 and Id3 in the IL of CS rats. Administration of the dopamine D2 receptor agonist bromocriptine prevented the inductions of Id1-3 in the IL of CS rats, whereas application of the dopamine D2 antagonist sulpiride induced significant expressions of Id1-3 in the IL of normal rats. Moreover, an in vitro study using primary cultured melanotrophs demonstrated a direct effect on Id1-3 inductions by dopamine suppression. These results suggest that the decreased dopamine levels in the IL during CS induce Id1-3 expressions in melanotrophs. Because Id family members inhibit various bHLH transcription factors, it is conceivable that the induced Id1-3 would cooperatively modulate gene expressions in melanotrophs under CS conditions to induce hormone secretion. (c) 2010 IBRO. Published by Elsevier Ltd. All rights reserved.

14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Filing documents with the Docket Management... Management System (DMS) and sending documents to the administrative law judge and Assistant Chief Counsel for Litigation. (a) The Federal Docket Management System (FDMS). (1) Documents filed in a civil penalty...

14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Filing documents with the Docket Management... Management System (DMS) and sending documents to the administrative law judge and Assistant Chief Counsel for Litigation. (a) The Federal Docket Management System (FDMS). (1) Documents filed in a civil penalty...

14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Filing documents with the Docket Management... Management System (DMS) and sending documents to the administrative law judge and Assistant Chief Counsel for Litigation. (a) The Federal Docket Management System (FDMS). (1) Documents filed in a civil penalty...

Dockets

EPA Pesticide Factsheets

The EPA Docket Center provides the public with access to agency information and rulemaking and non-rulemaking areas such as current and historical information on agency activities; and comments received from the public to inform agency decisions.

77 FR 45417 - Notice of Availability of Draft Environmental Assessment for Public Comment for the Longhorn...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... Longhorn Pipeline Reversal Project AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA... Parts 1500-1508, the Pipeline and Hazardous Materials Safety Administration (PHMSA) is announcing the...

Administrative Settlement Agreement and Order on Consent for Removal Action - CERCLA Docket No. 04-2010-3756

EPA Pesticide Factsheets

Contains legal agreement for the Huntsville Gas Company site under CERCLA Sections 104, 106(a), 107, and 122, Huntsville, Madison County, Alabama, November 24, 2009 Region ID: 04 DocID: 10685283, DocDate: 11-24-2009

77 FR 71813 - Connecticut; Amendment No. 3 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-04

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-4087-DR; Docket ID FEMA-2012-0002] Connecticut; Amendment No. 3 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2012-29207 Filed 12-3-12; 8:45 am] BILLING CODE...

76 FR 1189 - Virginia; Amendment No. 6 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1874-DR; Docket ID FEMA-2010-0002] Virginia; Amendment No. 6 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2011-134 Filed 1-6-11; 8:45 am] BILLING CODE 9111...

76 FR 36142 - Arkansas; Amendment No. 6 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1975-DR;Docket ID FEMA-2011-0001] Arkansas; Amendment No. 6 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2011-15319 Filed 6-20-11; 8:45 am] BILLING CODE...

75 FR 35828 - Kentucky; Amendment No. 6 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1912-DR; Docket ID FEMA-2010-0002] Kentucky; Amendment No. 6 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2010-15238 Filed 6-22-10; 8:45 am] BILLING CODE...

76 FR 26748 - Alabama; Amendment No. 6 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1971-DR; Docket ID FEMA-2011-0001] Alabama; Amendment No. 6 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2011-11288 Filed 5-6-11; 8:45 am] BILLING CODE 9111...

76 FR 58820 - New York; Amendment No. 9 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-4020-DR; Docket ID FEMA-2011-0001] New York; Amendment No. 9 to Notice of a Major Disaster..., Administrator, Federal Emergency Management Agency. [FR Doc. 2011-24323 Filed 9-21-11; 8:45 am] BILLING CODE...

77 FR 18306 - Agency Information Collection; Activity Under OMB Review; Airline Service Quality Performance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration [Docket ID No. RITA... Performance AGENCY: Research & Innovative Technology Administration (RITA), Bureau of Transportation... travelers information concerning the on-time performance history of flights that they are considering...

7 CFR 900.5 - Docket number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Docket number. 900.5 Section 900.5 Agriculture... Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the proceeding may be referred to by such number. ...

7 CFR 900.5 - Docket number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Docket number. 900.5 Section 900.5 Agriculture... Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the proceeding may be referred to by such number. ...

7 CFR 900.5 - Docket number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Docket number. 900.5 Section 900.5 Agriculture... Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the proceeding may be referred to by such number. ...

7 CFR 900.5 - Docket number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Docket number. 900.5 Section 900.5 Agriculture... Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the proceeding may be referred to by such number. ...

7 CFR 900.5 - Docket number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Docket number. 900.5 Section 900.5 Agriculture... Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the proceeding may be referred to by such number. ...

7 CFR 1.134 - Docket number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Docket number. 1.134 Section 1.134 Agriculture Office... Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes § 1.134 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the Hearing Clerk...

7 CFR 1.134 - Docket number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Docket number. 1.134 Section 1.134 Agriculture Office... Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes § 1.134 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the Hearing Clerk...

7 CFR 1.134 - Docket number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Docket number. 1.134 Section 1.134 Agriculture Office... Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes § 1.134 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the Hearing Clerk...

7 CFR 1.134 - Docket number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Docket number. 1.134 Section 1.134 Agriculture Office... Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes § 1.134 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the Hearing Clerk...

7 CFR 1.134 - Docket number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Docket number. 1.134 Section 1.134 Agriculture Office... Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes § 1.134 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the Hearing Clerk...

10 CFR 110.102 - Hearing docket.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Hearing docket. 110.102 Section 110.102 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND MATERIAL Hearings § 110.102 Hearing docket. For each hearing, the Secretary will maintain a docket which will include the hearing...

7 CFR 900.54 - Docket number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

7 CFR 1200.6 - Docket number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Docket number. 1200.6 Section 1200.6 Agriculture... Governing Proceedings To Formulate and Amend an Order § 1200.6 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the...

7 CFR 1200.6 - Docket number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Docket number. 1200.6 Section 1200.6 Agriculture... Governing Proceedings To Formulate and Amend an Order § 1200.6 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the...

7 CFR 900.54 - Docket number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

7 CFR 900.54 - Docket number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

7 CFR 1200.6 - Docket number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Docket number. 1200.6 Section 1200.6 Agriculture... Governing Proceedings To Formulate and Amend an Order § 1200.6 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the...

7 CFR 1200.6 - Docket number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Docket number. 1200.6 Section 1200.6 Agriculture... Governing Proceedings To Formulate and Amend an Order § 1200.6 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the hearing clerk and thereafter the...

7 CFR 900.54 - Docket number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

7 CFR 900.54 - Docket number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

76 FR 22944 - Pipeline Safety: Notice of Public Webinars on Implementation of Distribution Integrity Management...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-25

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... Management Programs AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION... Nation's gas distribution pipeline systems through development of inspection methods and guidance for the...

39 CFR 3002.11 - Office of Secretary and Administration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Employment Opportunity Officer for the Commission and manages the Commission's continuity of operations planning. (d) The Office of Secretary and Administration manages the Commission's records, including the... Office of Secretary and Administration manages the Commission's dockets and docket room, Web site...

39 CFR 3002.11 - Office of Secretary and Administration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Employment Opportunity Officer for the Commission and manages the Commission's continuity of operations planning. (d) The Office of Secretary and Administration manages the Commission's records, including the... Office of Secretary and Administration manages the Commission's dockets and docket room, Web site...

7 CFR 1.414 - Docket number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Docket number. 1.414 Section 1.414 Agriculture Office... Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620 et seq.) § 1.414 Docket number. Each proceeding, following its institution, shall be assigned a docket number by the Hearing Clerk, and thereafter the...

7 CFR 1.414 - Docket number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Docket number. 1.414 Section 1.414 Agriculture Office... Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620 et seq.) § 1.414 Docket number. Each proceeding, following its institution, shall be assigned a docket number by the Hearing Clerk, and thereafter the...

7 CFR 1.414 - Docket number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Docket number. 1.414 Section 1.414 Agriculture Office... Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620 et seq.) § 1.414 Docket number. Each proceeding, following its institution, shall be assigned a docket number by the Hearing Clerk, and thereafter the...

7 CFR 1.414 - Docket number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Docket number. 1.414 Section 1.414 Agriculture Office... Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620 et seq.) § 1.414 Docket number. Each proceeding, following its institution, shall be assigned a docket number by the Hearing Clerk, and thereafter the...

7 CFR 1.414 - Docket number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Docket number. 1.414 Section 1.414 Agriculture Office... Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620 et seq.) § 1.414 Docket number. Each proceeding, following its institution, shall be assigned a docket number by the Hearing Clerk, and thereafter the...

77 FR 19414 - Pipeline Safety: Public Comment on Leak and Valve Studies Mandated by the Pipeline Safety...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... Safety, Regulatory Certainty, and Job Creation Act of 2011 AGENCY: Pipeline and Hazardous Materials... Transportation (DOT), Pipeline and Hazardous Materials Safety Administration (PHMSA) is providing an important...

75 FR 15485 - Pipeline Safety: Workshop on Guidelines for Integrity Assessment of Cased Pipe

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID...: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of workshop. SUMMARY... ``Guidelines for Integrity Assessment of Cased Pipe in Gas Transmission Pipelines'' and related Frequently...

49 CFR 601.42 - Emergency relief docket.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Emergency Relief Docket in the publicly accessible DOT Docket Management System (DMS) (http://dms.dot.gov... message on its web page (http://www.fta.dot.gov) indicating the Emergency Relief Docket has been opened...

49 CFR 601.42 - Emergency relief docket.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Emergency Relief Docket in the publicly accessible DOT Docket Management System (DMS) (http://dms.dot.gov... message on its web page (http://www.fta.dot.gov) indicating the Emergency Relief Docket has been opened...

49 CFR 601.42 - Emergency relief docket.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Emergency Relief Docket in the publicly accessible DOT Docket Management System (DMS) (http://dms.dot.gov... message on its web page (http://www.fta.dot.gov) indicating the Emergency Relief Docket has been opened...

49 CFR 601.42 - Emergency relief docket.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Emergency Relief Docket in the publicly accessible DOT Docket Management System (DMS) (http://dms.dot.gov... message on its web page (http://www.fta.dot.gov) indicating the Emergency Relief Docket has been opened...

49 CFR 601.42 - Emergency relief docket.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Emergency Relief Docket in the publicly accessible DOT Docket Management System (DMS) (http://dms.dot.gov... message on its web page (http://www.fta.dot.gov) indicating the Emergency Relief Docket has been opened...

Procedure for Electronic Management of Rulemaking and Other Docketed Records in the Federal Docket Management System

EPA Pesticide Factsheets

This procedure identifies the specific requirements, processes and supporting documents EPA uses to electronically manage rulemaking and other docketed records in the Federal Docket Management System (FDMS).

78 FR 146 - Notice of Availability of Final Environmental Assessment and Finding of No Significant Impact for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... Impact for the Longhorn Pipeline Reversal Project AGENCY: Pipeline and Hazardous Materials Safety... regulations, 40 CFR parts 1500-1508, the Pipeline and Hazardous Materials Safety Administration (PHMSA) is...

SNP ID-info: SNP ID searching and visualization platform.

PubMed

Yang, Cheng-Hong; Chuang, Li-Yeh; Cheng, Yu-Huei; Wen, Cheng-Hao; Chang, Phei-Lang; Chang, Hsueh-Wei

2008-09-01

Many association studies provide the relationship between single nucleotide polymorphisms (SNPs), diseases and cancers, without giving a SNP ID, however. Here, we developed the SNP ID-info freeware to provide the SNP IDs within inputting genetic and physical information of genomes. The program provides an "SNP-ePCR" function to generate the full-sequence using primers and template inputs. In "SNPosition," sequence from SNP-ePCR or direct input is fed to match the SNP IDs from SNP fasta-sequence. In "SNP search" and "SNP fasta" function, information of SNPs within the cytogenetic band, contig position, and keyword input are acceptable. Finally, the SNP ID neighboring environment for inputs is completely visualized in the order of contig position and marked with SNP and flanking hits. The SNP identification problems inherent in NCBI SNP BLAST are also avoided. In conclusion, the SNP ID-info provides a visualized SNP ID environment for multiple inputs and assists systematic SNP association studies. The server and user manual are available at http://bio.kuas.edu.tw/snpid-info.

22 CFR 102.27 - Docket.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Docket. 102.27 Section 102.27 Foreign Relations... other than the Director of the Office of Aviation and summaries of oral communications prepared in...) All comments submitted under this subpart and placed in the docket, are available for public...

76 FR 31388 - Idaho Disaster #ID-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12603 and 12604] Idaho Disaster ID-00014... declaration of a major disaster for Public Assistance Only for the State of Idaho (FEMA-- 1987--DR), dated 05..., Clearwater, Idaho, Nez Perce, Shoshone, Nez Perce Tribe. The Interest Rates are: Percent For Physical Damage...

75 FR 45682 - Idaho Disaster #ID-00010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-03

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12250 and 12251] Idaho Disaster ID-00010... declaration of a major disaster for Public Assistance Only for the State of Idaho (FEMA-1927- DR), dated 07/27... adversely affected by the disaster: Primary Counties: Adams, Gem, Idaho, Lewis, Payette, Valley, Washington...

76 FR 20032 - Thomas E. Mitchell, M.D.; Dismissal of Proceeding

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-11

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-7] Thomas E. Mitchell, M.D.; Dismissal of Proceeding On September 11, 2009, the Deputy Assistant Administrator, Office of Diversion... procedural misconduct, misrepresentations and the subsequent illegitimate denial of due process.'' Id. On...

76 FR 303 - Pipeline Safety: Safety of On-Shore Hazardous Liquid Pipelines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-04

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 195 [Docket ID PHMSA-2010-0229] RIN 2137-AE66 Pipeline Safety: Safety of On-Shore Hazardous Liquid Pipelines AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of...

76 FR 70953 - Pipeline Safety: Safety of Gas Transmission Pipelines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 192 [Docket ID PHMSA-2011-0023] RIN 2137-AE72 Pipeline Safety: Safety of Gas Transmission Pipelines AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA); DOT. ACTION: Advance notice of...

10 CFR 820.10 - Office of the docketing clerk.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions commencing...

10 CFR 820.10 - Office of the docketing clerk.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions commencing...

49 CFR 211.5 - Regulatory docket.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... Department of Transportation, Docket Operations (M-30), West Building Ground Floor, Room W12-140, 1200 New...://www.regulations.gov. All docketed materials are available for viewing and may be downloaded for...

77 FR 58488 - Hawaii State Plan for Occupational Safety and Health

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... announces the Occupational Safety and Health Administration's (OSHA) decision to modify the Hawaii State... DEPARTMENT OF LABOR Occupational Safety and Health Administration 29 CFR Part 1952 [Docket ID. OSHA 2012-0029] RIN 1218-AC78 Hawaii State Plan for Occupational Safety and Health AGENCY: Occupational...

77 FR 70166 - Provisions of the Food and Drug Administration Safety and Innovation Act Related to Medical Gases...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

...; Establishment of a Public Docket AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is establishing a public docket for information pertaining to FDA's... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-1090...

77 FR 5088 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... Relief Docket for calendar year 2012 so grantees and subgrantees affected by national or regional emergencies may request relief from FTA administrative requirements set forth in FTA policy statements.... Grantees and subgrantees are strongly encouraged to contact their FTA regional office and notify FTA of the...

75 FR 5639 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-03

... Relief Docket for calendar year 2010 so grantees and subgrantees affected by national or regional emergencies may request relief from FTA administrative requirements set forth in FTA policy statements... subgrantee may contact any FTA regional office or FTA headquarters and request that FTA staff submit the...

76 FR 4149 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... Relief Docket for calendar year 2011 so grantees and subgrantees affected by national or regional emergencies may request relief from FTA administrative requirements set forth in FTA policy statements... subgrantee may contact any FTA regional office or FTA headquarters and request that FTA staff submit the...

76 FR 82311 - Food and Drug Administration Transparency Initiative: Food and Drug Administration Report on Good...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0247] Food and Drug Administration Transparency Initiative: Food and Drug Administration Report on Good Guidance Practices: Improving Efficiency and Transparency; Availability AGENCY: Food and Drug...

7 CFR 1200.6 - Docket number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Docket number. 1200.6 Section 1200.6 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Governing Proceedings To Formulate and Amend an Order § 1200.6 Docket number. Each proceeding, immediately...

Administrative Settlement Agreement and Order on Consent for Removal Action, CERCLA Docket No. 04-2009-3979, Forshaw Chemicals, Inc.

EPA Pesticide Factsheets

Contains legal agreement for the Forshaw Chemicals site under CERCLA Sections 104, 106(a), 107 and 122, Charlotte, Mecklenburg County, North Carolina, August 11, 2009 Region ID: 04 DocID: 10539125, DocDate: 08-11-2009

76 FR 51424 - Satinder Dang, M.D.; Revocation of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-4] Satinder Dang, M.D... Control, Drug Enforcement Administration, issued an Order to Show Cause to Satinder K. Dang, M.D....'' Id. (citing Harrell E. Robinson, M.D., 74 FR 61370, 61376-77 (2010)). The ALJ also found that...

75 FR 32836 - Pipeline Safety: Workshop on Public Awareness Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-09

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... American Public Gas Association Association of Oil Pipelines American Petroleum Institute Interstate... the pipeline industry). Hazardous Liquid Gas Transmission/Gathering Natural Gas Distribution (10...

78 FR 41803 - Establishment of a Public Docket for Comment on the Report Prepared Under the Food and Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-11

... Safety and Innovation Act Section 1138 AGENCY: Food and Drug Administration, HHS. ACTION: Establishment... Administration Safety and Innovation Act (FDASIA) Section 1138, enacted July 9, 2012, and posted on the FDA Web... comments to http://www.regulations.gov . Submit written comments to the Division of Dockets Management (HFA...

76 FR 78872 - EPA Responses to State and Tribal 2008 Ozone Designation Recommendations: Notice of Availability...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... the online instructions for submitting comments. Email: [email protected] . Attention Docket ID No. EPA-HQ-OAR-2008-0476. Fax: (202) 566-9744. Attention Docket ID No. EPA-HQ-OAR- 2008-0476. Mail: Air Docket, Attention Docket ID No. EPA-HQ-OAR-2008- 0476, Environmental Protection Agency, Mail Code...

76 FR 22863 - Designation for the Lewiston, ID Area

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-25

... the Lewiston, ID Area AGENCY: Grain Inspection, Packers and Stockyards Administration, USDA. ACTION... official services in the geographic area previously serviced by Lewiston Grain Inspection Service, Inc. (Lewiston). Applications were due by February 3, 2011. Washington was the sole applicant for designation to...

76 FR 36042 - EPA Responses to State and Tribal 2008 Lead Designation Recommendations: Notice of Availability...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... newly deployed monitors can be considered in making appropriate designation decisions. States previously... submitting comments. E-mail: [email protected] . Attention Docket ID No. EPA-HQ-OAR-2009-0443. Fax: 202-566-9744. Attention Docket ID No. EPA-HQ-OAR- 2009-0443. Mail: Air Docket, Attention Docket ID No. EPA...

78 FR 72676 - Draft National Pollutant Discharge Elimination System (NPDES) General Permit for Stormwater...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

.... Email: [email protected] , Attention Docket ID No. EPA- HQ-OW-2012-0803. Fax: (202) 566-9744 Mail: Water Docket, Environmental Protection Agency, Mailcode: 28221T, Attention Docket ID No. EPA-HQ-OW-2012..., Room 3334, 1301 Constitution Avenue NW., Washington, DC, Attention Docket ID No. EPA-HQ-OW-2012-0803...

77 FR 18304 - Agency Information Collection; Activity Under OMB Review; Report of Financial and Operating...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... Operating Statistics for Large Certificated Air Carriers AGENCY: Research & Innovative Technology... DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration [Docket ID Number... Operating Statistics for Large Certificated Air Carriers. Form No.: BTS Form 41. Type Of Review...

75 FR 30860 - Shepard Ginandes, M.D.; Revocation of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-02

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-14] Shepard Ginandes, M.D... Administration, issued an Order to Show Cause and Immediate Suspension of Registration to Shepard Ginandes, M.D... right to a hearing.'' Id. (citing 21 CFR 1301.43(d) & (e)). On September 30, 2009, the Order was served...

Badging, Real ID

Science.gov Websites

. REAL ID LANL Impacts and Solutions The federal government has determined New Mexico is non-compliant Identification Cards whom will also become Non-Compliant. Access through LANL Vehicle Access Portals unaffected alternate ID if they are coming from "non-compliant" REAL-ID states LANS and the Field Office have

75 FR 13342 - Pipeline Safety: Workshop on Distribution Pipeline Construction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... natural gas distribution construction. Natural gas distribution pipelines are subject to a unique subset... distribution pipeline construction practices. This workshop will focus solely on natural gas distribution...

Administrative Settlement Agreement and Order on Consent for Removal Action - Kentucky Wood Preserving Superfund Site. Docket No. 04-2009-3762

EPA Pesticide Factsheets

Contains legal agreement for the Kentucky Wood Preserving Superfund site under CERCLA Sections 104, 106(a), 107 and 122, Winchester, Kentucky, February 9, 2009 Region ID: 04 DocID: 10452978, DocDate: 02-09-2009

78 FR 28943 - Agency Information Collection; Activity Under OMB Review; Passenger Origin-Destination Survey Report

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-16

... techniques or other forms of information technology. DATES: Written comments should be submitted by July 15... DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration [Docket ID Number RITA 2008-0002] Agency Information Collection; Activity Under OMB Review; Passenger Origin-Destination...

78 FR 5866 - Pipeline Safety: Annual Reports and Validation

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID PHMSA-2012-0319] Pipeline Safety: Annual Reports and Validation AGENCY: Pipeline and Hazardous Materials... 2012 gas transmission and gathering annual reports, remind pipeline owners and operators to validate...

33 CFR 1.05-25 - Public docket.

Code of Federal Regulations, 2010 CFR

2010-07-01

... docket. Public dockets for Coast Guard rulemakings are available electronically at http://www.regulations... http://www.regulations.gov. Paragraph (a) of this section describes how to access and view these... available for inspection at the appropriate Captains of the Port Office or online at http://www.regulations...

75 FR 34960 - Import Administration IA ACCESS Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Part 351 [Docket No. 100602237-0250-02] Import Administration IA ACCESS Pilot Program AGENCY: Import Administration, International Trade Administration, Department of Commerce. ACTION: Public notice and request for comments; correction...

78 FR 20330 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-04

... instruction of emergency preparedness officials and other persons in the organization, operation, and techniques of emergency preparedness, and to conduct or operate schools or classes. The Administrator... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID: FEMA-2013-0009...

78 FR 14877 - Pipeline Safety: Incident and Accident Reports

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID PHMSA-2013-0028] Pipeline Safety: Incident and Accident Reports AGENCY: Pipeline and Hazardous Materials... PHMSA F 7100.2--Incident Report--Natural and Other Gas Transmission and Gathering Pipeline Systems and...

77 FR 61825 - Pipeline Safety: Notice of Public Meeting on Pipeline Data

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-11

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... program performance measures for gas distribution, gas transmission, and hazardous liquids pipelines. The... distribution pipelines (49 CFR 192.1007(e)), gas transmission pipelines (49 CFR 192.945) and hazardous liquids...

75 FR 9018 - Pipeline Safety: Random Drug Testing Rate

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-26

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID PHMSA-2010-0034] Pipeline Safety: Random Drug Testing Rate AGENCY: Pipeline and Hazardous Materials... pipelines and operators of liquefied natural gas facilities must select and test a percentage of covered...

77 FR 2606 - Pipeline Safety: Random Drug Testing Rate

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-18

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID PHMSA-2012-0004] Pipeline Safety: Random Drug Testing Rate AGENCY: Pipeline and Hazardous Materials... pipelines and operators of liquefied natural gas facilities must select and test a percentage of covered...

78 FR 62417 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Parts 351, 354, and 356 RIN 0625-AA97 [Docket No. 130927845-3845-01] Import Administration; Change of Agency Name AGENCY: Import Administration, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY...

77 FR 14404 - Guidance for the Public, Food and Drug Administration (FDA) Advisory Committee Members, and FDA...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2002-D-0094; (formerly Docket No. 02D-0049)] Guidance for the Public, Food and Drug Administration (FDA) Advisory... Food and Drug Administration (FDA) is announcing the availability of a guidance for the public, FDA...

21 CFR 12.100 - Administrative record of a hearing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Dockets Management under §§ 12.20 through 12.22; (3) The notice of hearing published under § 12.35; (4... documentary evidence and written testimony, pleadings, statements of position, briefs, and other similar... Dockets Management by the presiding officer or any participant; (b) The record of the administrative...

76 FR 21692 - National Emission Standards for Hazardous Air Pollutants: Primary Lead Smelting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-18

[email protected] . Attention Docket ID Number EPA-HQ-OAR-2004-0305. Fax: (202) 566-9744. Attention Docket... (6102T), EPA West (Air Docket), Attention Docket ID Number EPA- HQ-OAR-2004-0305, U.S. Environmental... Agency, EPA West (Air Docket), Room 3334, 1301 Constitution Avenue, NW., Washington, DC 20004, Attention...

Endangerment and Cause or Contribute Findings for Greenhouse Gases under the Clean Air Act

EPA Pesticide Factsheets

Read the Endangerment and Cause or Contribute Findings for Greenhouse Gases under the Clean Air Act, signed by the Administrator on December 7, 2009. The final findings were published in the Federal Register under Docket ID No. EPA-HQ-OAR-2009-0171.

78 FR 48697 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-09

... INFORMATION: FEMA's Homeland Security Grant Program (HSGP) is an important part of the Administration's larger... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID: FEMA-2013-0034... concerning the collection of information to administer the Homeland Security Grant Program (HSGP). DATES...

ADMINISTRATIVE SETTLEMENT AGREEMENT AND ORDER ON CONSENT FOR REMEDIAL INVESTIGATION/FEASIBILITY STUDY, B.F. GOODRICH. CERCLA DOCKET NO. 04-2010-3761.

EPA Pesticide Factsheets

legal agreement about the B. F. Goodrich Superfund Site Calvert City, Marshall County, Kentucky between EPA and Goodrich Corporation, PolyOne Corporation, and Westlake Vinyls, Inc. Region ID: 04 DocID: 10453129, DocDate: 12-09-2009

75 FR 73964 - Safety Zone; USS Fort Worth Launch, Marinette, WI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2010-1044] RIN 1625... the docket are part of docket USCG-2010-1044 and are available online by going to http://www...-2010-1044 in the Docket ID box, pressing Enter, and then clicking on the item in the Docket ID column...

75 FR 47594 - Board of Scientific Counselors, Executive Committee Meeting-August 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-06

[email protected] , Attention Docket ID No. EPA-HQ-ORD-2010-0661. Fax: Fax comments to: (202) 566-0224, Attention Docket ID No. EPA-HQ-ORD-2010-0661. Mail: Send comments by mail to: Board of Scientific Counselors...., Washington, DC 20004, Attention Docket ID No. EPA-HQ-ORD-2010-0661. Hand Delivery or Courier: Deliver...

75 FR 31678 - Export Administration Regulations: Technical Corrections

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

... and 774 [Docket No. 0907271167-91198-01] RIN 0694-AE69 Export Administration Regulations: Technical... clarifies language concerning the de minimis provisions of the Export Administration Regulations and certain... Items The Export Administration Regulations (EAR) generally do not apply to items that were made and are...

78 FR 51176 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2013-0012] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army, (OAA-AAHS....regulations.gov as they are received without change, including any personal identifiers or contact information...

78 FR 63970 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2013-0034] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army (OAA-RPA), DoD... they are received without change, including any personal identifiers or contact information. FOR...

75 FR 38090 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... DEPARTMENT OF DEFENSE Department of the Army [Docket ID USA-2010-0016] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army, (OAA-AAHS-RDR... without change, including any personal identifiers or contact information. FOR FURTHER INFORMATION CONTACT...

Id-1 and Id-2 genes and products as markers of epithelial cancer

DOEpatents

Desprez, Pierre-Yves [El Cerrito, CA; Campisi, Judith [Berkeley, CA

2008-09-30

A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

Id-1 and Id-2 genes and products as markers of epithelial cancer

DOEpatents

Desprez, Pierre-Yves [El Cerrito, CA; Campisi, Judith [Berkeley, CA

2011-10-04

A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

Establishment of a public docket for medical device/radiological health policy statements and operating procedure guides--FDA. Notice.

PubMed

1993-07-27

The Food and Drug Administration (FDA) is announcing that it is establishing a public docket for policy speeches, policy statements, and standard operating procedure guides pertaining to product evaluation and regulatory enforcement for its medical device and radiological health programs. The docket will operate on a 1-year trial basis and will serve both as a repository for critical policy documents generated by the Center for Devices and Radiological Health (CDRH) and as a public display mechanism for access by representatives of the industry and other interested persons. This action is one element of an overall communications initiative to ensure uniform and timely access to important information.

78 FR 52910 - Proposed Collection; Comment Request; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-27

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-HA-0180] Proposed Collection... DoD-2008-HA-0180. The Docket ID is corrected to read as set forth in this notice. The corrected Docket ID should read DoD-2013-HA-0180. DATES: This notice is effective on August 27, 2013. FOR FURTHER...

75 FR 12232 - Board of Scientific Counselors, Executive Committee Meeting-April 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-15

... business is finished. Requests for the draft agenda or for making oral presentations at the meeting will be... , Attention Docket ID No. EPA-HQ-ORD-2010-0202. Fax: Fax comments to: (202) 566-0224, Attention Docket ID No... 20004, Attention Docket ID No. EPA-HQ-ORD-2010-0202. Hand Delivery or Courier. Deliver comments to: EPA...

39 CFR 3001.13 - Docket and hearing calendar.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Docket and hearing calendar. 3001.13 Section 3001.13 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES OF PRACTICE AND PROCEDURE Rules of... remotely via the Commission's Web site, or viewed at the Commission's docket section during regular...

76 FR 30236 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0061] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31004 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0069] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18300 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0031] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0040] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0055] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0066] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0014] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0012] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0042] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 6183 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0001] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 26793 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0041] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration Docket No. MARAD-2011-0052 Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 51467 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0105] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30237 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0054] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55733 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0113] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 29332 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0053] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0065] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 35943 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0075] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011-0032] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 13701 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0024] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31006 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0064] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30755 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-26

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0068] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011 0034] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

75 FR 6209 - Guidance for Industry and Food and Drug Administration; Guidance for the Use of Bayesian...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2006-D-0410] (formerly Docket No. 2006D-0191) Guidance for Industry and Food and Drug Administration; Guidance for the Use of Bayesian Statistics in Medical Device Clinical Trials; Availability AGENCY: Food and Drug...

77 FR 6857 - Pipeline Safety: Notice of Public Meetings on Improving Pipeline Leak Detection System...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-09

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... installed to lessen the volume of natural gas and hazardous liquid released during catastrophic pipeline... p.m. Panel 3: Considerations for Natural Gas Pipeline Leak Detection Systems 3:30 p.m. Break 3:45 p...

78 FR 57445 - Charging Standard Administrative Fees for Nonprogram-Related Information

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information AGENCY: Social Security Administration. ACTION: Notice of standard... administration of a program under the Social Security Act (Act). SUPPLEMENTARY INFORMATION: Section 1106 of the...

Registration Review Docket Opening Schedule

EPA Pesticide Factsheets

Dockets are opened on a fiscal year schedule for reevaluation of all pesticides. They are subdivided into conventional pesticides, antimicrobials, biochemicals, and microbials. The schedules for 2014 to 2017 are attached.

78 FR 67210 - Charging Standard Administrative Fees for Nonprogram-Related Information; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information; Correction AGENCY: Social Security Administration. ACTION: Notice... Social Security Administration published a document in the Federal Register of September 18, 2013...

Negotiating roadblocks to IDS-physician equity joint ventures.

PubMed

Dubow, S F; Benoff, M

1998-09-01

Integrated delivery systems (IDSs) may find that forming an equity joint venture relationship with a physician group practice is the best way to integrate physicians into their networks. IDSs have a choice between two basic equity structures: affiliated group practice, in which a management services organization (MSO) handles all practice management infrastructure and the physician group is a physician-only organization; and integrated group practice, in which the physician group encompasses both the physician practice and the administrative infrastructure. The choice of equity structure and how it should be implemented hinge on several legal issues, including the existence of a corporate-practice-of-medicine statute in the IDS's state, compliance with the Federal antikickback statute and Stark laws, and various issues regarding the IDS's tax-exempt status. IDSs also should consider pragmatic issues, particularly those associated with aligning the economic incentives of the two partners.

78 FR 78321 - Early Warning Reporting, Foreign Defect Reporting, and Motor Vehicle and Equipment Recall...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration 49 CFR Parts 573, 577, and 579 [Docket No. NHTSA--2012-0068; Notice 3] RIN 2127-AK72 Early Warning Reporting, Foreign Defect... final rule. Id. Manufacturers with early warning reporting (EWR) accounts may obtain a copy of the VIN...

77 FR 5472 - Pipeline Safety: Expanding the Use of Excess Flow Valves in Gas Distribution Systems to...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-03

..., Regulatory Certainty, and Job Creation Act of 2011 (PL112-90), have imposed additional demands on their... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 192 [Docket ID PHMSA-2011-0009] RIN 2137-AE71 Pipeline Safety: Expanding the Use of Excess Flow Valves...

ID2 collaborates with ID3 to suppress iNKT and innate-like tumors1

PubMed Central

Li, Jia; Roy, Sumedha; Kim, Young-Mi; Li, Shibo; Zhang, Baojun; Love, Cassandra; Reddy, Anupama; Rajagopalan, Deepthi; Dave, Sandeep; Diehl, Anna Mae; Zhuang, Yuan

2017-01-01

Inhibitor of DNA binding (ID) proteins, including ID1-4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell types. Although upregulation of Id proteins has been associated with a broad spectrum of tumors, recent studies have identified that ID3 plays a tumor suppressor role in the development of Burkitt’s lymphoma in humans and Hepatosplenic T cell lymphomas in mice. Here, we report rapid lymphoma development in Id2/Id3 double knockout (L-DKO) mice caused by unchecked expansion of either invariant Natural Killer T (iNKT) cells, or a unique subset of innate-like, CD1d-independent T cells. These populations started expansion in neonatal mice and, upon malignant transformation, caused fatality at age between 3–11 months. The malignant cells also gave rise to lymphomas upon transfer to Rag-deficient and wild-type hosts, reaffirming their inherent tumorigenic potential. Microarray analysis revealed a significantly modified program in these neonatal iNKT cells that ultimately led to their malignant transformation. The lymphoma cells demonstrated chromosome instability, along with upregulation of several different signaling pathways, including the cytokine-cytokine receptor interaction pathway, which can promote their expansion and migration. Dysregulation of genes with reported driver mutations and the NF-kB pathway were found to be shared between L-DKO lymphomas and human NKT tumors. Our work identifies a distinct premalignant state and multiple tumoriogenic pathways caused by loss function of ID2 and ID3. Thus, conditional deletion of Id2 and Id3 in developing T cells establishes a unique animal model for iNKT and relevant innate-like lymphomas. PMID:28258199

75 FR 27004 - Petitions for Modification

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-13

... Mountain Processing, Inc., Clover Fork No. 1 Mine, (MSHA I.D. No. 15-18647), Docket No. M-2009-024-C; (b) Huff Creek No. 1 Mine (MSHA I.D. No. 15-17234), Docket No. M-2010-021-C; and (c) Darby Fork No. 1 Mine, (MSHA I.D. No. 15-02263), Docket No. M-2010-022-C. These mines are located in Harlan County, Kentucky...

76 FR 55928 - Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Food and Drug Administration Health Professional Organizations Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. The Food and Drug Administration (FDA) is announcing a...

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome

PubMed Central

Siew, Wei-Hong; Tan, Kai-Leng; Babaei, Maryam Abbaspour; Cheah, Pike-See; Ling, King-Hwa

2013-01-01

Intellectual disability (ID) is one of the many features manifested in various genetic syndromes leading to deficits in cognitive function among affected individuals. ID is a feature affected by polygenes and multiple environmental factors. It leads to a broad spectrum of affected clinical and behavioral characteristics among patients. Until now, the causative mechanism of ID is unknown and the progression of the condition is poorly understood. Advancement in technology and research had identified various genetic abnormalities and defects as the potential cause of ID. However, the link between these abnormalities with ID is remained inconclusive and the roles of many newly discovered genetic components such as non-coding RNAs have not been thoroughly investigated. In this review, we aim to consolidate and assimilate the latest development and findings on a class of small non-coding RNAs known as microRNAs (miRNAs) involvement in ID development and progression with special focus on Down syndrome (DS) and X-linked ID (XLID) [including Fragile X syndrome (FXS)]. PMID:23596395

75 FR 15741 - Applied Materials; Boise, ID; Notice of Termination of Investigation

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,443] Applied Materials; Boise, ID; Notice of Termination of Investigation Pursuant to Section 221 of the Trade Act of 1974, as... of Applied Materials, Boise, Idaho. The petitioning group of workers is covered by an active...

WIPP Docket A-93-02

EPA Pesticide Factsheets

WIPP Docket No. A-93-02 contains information that EPA considered in making its 1998 decision to certify that the Department of Energy had met the compliance criteria established by 40 CFR Part 194 and disposal regulations set by 40 CFR Part 191.

10 CFR 2.303 - Docket.

Code of Federal Regulations, 2013 CFR

2013-01-01

... COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Rules of General Applicability: Hearing Requests, Petitions... Powers, and General Hearing Management for NRC Adjudicatory Hearings § 2.303 Docket. The Secretary shall..., as appropriate. The Secretary shall maintain all files and records of proceedings, including...

10 CFR 2.303 - Docket.

Code of Federal Regulations, 2014 CFR

2014-01-01

... COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Rules of General Applicability: Hearing Requests, Petitions... Powers, and General Hearing Management for NRC Adjudicatory Hearings § 2.303 Docket. The Secretary shall..., as appropriate. The Secretary shall maintain all files and records of proceedings, including...

75 FR 2890 - OSHA Listens: Occupational Safety and Health Administration Stakeholder Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-19

... DEPARTMENT OF LABOR Occupational Safety and Health Administration [Docket No. OSHA-2010-0004] OSHA Listens: Occupational Safety and Health Administration Stakeholder Meeting AGENCY: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Notice of public meeting. SUMMARY: The Occupational Safety...

78 FR 773 - Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

...., Commercial/ Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford... financial reporting. The group develops databases for creating reports for corporate, regulatory, and... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,815] Hartford Financial...

75 FR 62530 - Southeastern Power Administration; Notice of Filing

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2010-10-12

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-8-000] Southeastern Power Administration; Notice of Filing October 1, 2010. Take notice that on September 16, 2010, the... power from Southeastern Power Administration's Kerr-Philpott System, and under the authority vested in...

76 FR 49763 - Bonneville Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-8-000] Bonneville Power Administration; Notice of Filing Take notice that on August 1, 2011, the Bonneville Power Administration submitted its Proposed 2012 Wholesale Power and Transmission Rates Rate Adjustment, for confirmation and...

75 FR 65624 - Southeastern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-11-000] Southeastern Power Administration; Notice of Filing October 19, 2010. Take notice that on September 30, 2010, the... Commission by Delegation Order No. 00-037.00, submitted Southeastern Power Administration (Southeastern) Rate...

76 FR 66925 - Guidance for 1-Hour SO2

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-28

... making decisions concerning each document. The draft of the guidance document is available online at http... instructions for submitting comments. Email: [email protected] . Attention Docket ID No. EPA-HQ-OAR-2010-1059. Fax: (202) 566-9744. Attention Docket ID No. EPA-HQ-OAR- 2010-1059. Mail: Air Docket, Attention...

Social Science Docket, 2000-2001.

ERIC Educational Resources Information Center

Singer, Alan, Ed.

2001-01-01

A joint publication of the New York and New Jersey State Councils for the Social Studies, "Social Science Docket" presents K-12 teachers with resources covering the social science disciplines, including history, economics, political science, sociology, geography, anthropology, and psychology. Each issue includes theme-related and…

77 FR 56838 - Southeastern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF12-4-000] Southeastern Power Administration; Notice of Filing Take notice that on September 5, 2012, the Southeastern Power Administration submitted its Rate Order No. SEPA-56 concerning rate and repayment data for the Georgia-Alabama...

76 FR 60015 - Southeastern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-28

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-12-000] Southeastern Power Administration; Notice of Filing Take notice that on September 8, 2011, the Southeastern Power Administration submitted its Rate Order No. SEPA-54 concerning rate and repayment data for the Jim Woodruff...

78 FR 64494 - Southwestern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF14-1-000] Southwestern Power Administration; Notice of Filing Take notice that on October 3, 2013, the Deputy Secretary of the... interim basis in Rate Order SWPA- 66, Southwestern Power Administration Integrated System Rates for the...

77 FR 5247 - Southwestern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF12-1-000] Southwestern Power Administration; Notice of Filing Take notice that on January 9, 2012, the Deputy Secretary of the... Administration Integrated System Rates, Rate Schedule P-11, Wholesale Rates for Hydro Peaking Power, Rate...

76 FR 60015 - Southeastern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-28

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-13-000] Southeastern Power Administration; Notice of Filing Take notice that on September 14, 2011, the Southeastern Power Administration submitted its Rate Order No. SEPA-55 concerning rate and repayment data for the Cumberland System...

75 FR 52527 - Southwestern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-6-000] Southwestern Power Administration; Notice of Filing August 19, 2010. Take notice that on August 17, 2010, the Department of Energy, Southwestern Power Administration, pursuant to Order 714 \\1\\ and section 35.28(e),\\2...

75 FR 67960 - Southeastern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-04

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-1-000] Southeastern Power Administration; Notice of Filing October 28, 2010. Take notice that on October 6, 2010, the Southeastern Power Administration, pursuant to Order No. 714,\\1\\ submitted its Baseline Filing, to be effective...

75 FR 15439 - Food and Drug Administration/Xavier University Global Medical Device Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001] Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA...

78 FR 15957 - Food and Drug Administration/Xavier University Global Medical Device Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001] Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA...

77 FR 10537 - Food and Drug Administration/Xavier University Global Medical Device Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001] Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA...

Federal Agency Hazardous Waste Compliance Docket

EPA Pesticide Factsheets

The Federal Agency Hazardous Waste Compliance Docket contains information reported to EPA by federal facilities that manage hazardous waste or from which hazardous substances, pollutants, or contaminants have been - or may be - released.

78 FR 64494 - Southwestern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF14-2-000] Southwestern Power Administration; Notice of Filing Take notice that on October 3, 2013, the Deputy Secretary of the... interim basis in Rate Order SWPA- 67, Southwestern Power Administration annual rate for the sale of power...

77 FR 65679 - Southwestern Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-30

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF13-1-000] Southwestern Power Administration; Notice of Filing Take notice that on October 18, 2012, the Deputy Secretary of the... an interim basis in Rate Order SWPA-64, Southwestern Power Administration annual rate for the sale of...

75 FR 16345 - Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

.... FDA-1999-N-3539] (formerly Docket No. 1999N-4783) Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment AGENCY: Food and Drug Administration, HHS. ACTION: Final rule... Subjects in 21 CFR Part 10 Administrative practice and procedure, News media. 0 Therefore, under the...

Federal Agency Hazardous Waste Compliance Docket

EPA Pesticide Factsheets

List of the Federal Agency Hazardous Waste Compliance Docket Facilities comprised of four lists: National Priorities List (NPL), Non-National Priorities List, Base Realignment and Closure Act (BRAC), and Resource Conservation and Recovery Act (RCRA).

7 CFR 1944.412 - Docket preparation.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.412 Docket...-Help Technical Assistance Grant Agreement (Exhibit A) 2 1 1-O 1-C Any Personnel Forms to be used 2 1-O...

76 FR 58805 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-9-000] Western Area Power Administration; Notice of Filing Take notice that on September 7, 2011, the Western Area Power Administration submitted its Rate Order No. WAPA-156, concerning power, transmission, and ancillary service...

77 FR 15096 - Bonneville Power Administration; Notice of Compliance Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL11-44-002] Bonneville Power Administration; Notice of Compliance Filing Take notice that on March 6, 2012, the Bonneville Power Administration (Bonneville) submitted a compliance filing with Pro Forma sheets in response to the...

77 FR 65188 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-25

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-4-002] Western Area Power Administration; Notice of Filing Take notice that on September 12, 2012, Western Area Power Administration submitted revisions to its Open Access Transmission Tariff to correct formatting and technical...

76 FR 17646 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-30

... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... adverse effects on human health or the environment. Registration review dockets contain information that... pesticide's registration is based on current scientific and other knowledge, including its effects on human...

78 FR 35937 - Food and Drug Administration Decisions for Investigational Device Exemption Clinical...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0790] Food and Drug Administration Decisions for Investigational Device Exemption Clinical Investigations; Draft Guidance for Industry and Food and Drug Administration Staff; Availability AGENCY: Food and Drug...

78 FR 55728 - Society of Clinical Research Associates-Food and Drug Administration: Food and Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-11

...: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food and Drug Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001] Society of Clinical Research Associates-Food and Drug Administration: Food and Drug Administration...

76 FR 65718 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-14-000] Western Area Power Administration; Notice of Filing Take notice that on September 23, 2011, Western Area Power Administration submitted its Rate Order No. WAPA-151 concerning rate and repayment data for Network Integration...

76 FR 12957 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-4-001] Western Area Power Administration; Notice of Filing Take notice that on March 3, 2011, the Western Area Power Administration, submitted its Open Access Transmission Tariff Compliance Filing, to be effective March 2, 2011...

76 FR 8726 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-4-000] Western Area Power Administration; Notice of Filing Take notice that on February 3, 2011, the Western Area Power Administration, pursuant to Order No. 714,\\1\\ and the Federal Energy Regulatory Commission's (Commission) Order...

78 FR 62014 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-11-001] Western Area Power Administration; Notice of Filing Take notice that on September 17, 2013, the Western Area Power Administration submitted its Rate Order No. WAPA-1626, concerning extension of the Parker-Davis Project firm...

76 FR 58805 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-10-000] Western Area Power Administration; Notice of Filing Take notice that on September 7, 2011, the Western Area Power Administration submitted its Rate Order No. WAPA-155 and certain Rate Schedules concerning formula rates...

75 FR 65624 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-10-000] Western Area Power Administration; Notice of Filing October 19, 2010. Take notice that on September 30, 2010, Western Area Power Administration submitted a tariff filing pursuant to its Open Access Transmission Tariff, to...

77 FR 65546 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-29

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-7-000] Western Area Power Administration; Notice of Filing Take notice that on July 14, 2011, Western Area Power Administration submitted its revised version of its Tariff Title for the Western Rate Schedules database, to be...

77 FR 65545 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-29

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-7-001] Western Area Power Administration; Notice of Filing Take notice that on August 13, 2012, Western Area Power Administration submitted its revised version of its Western Rate Schedules, to be effective October 1, 2012. Any...

Evaluation of red blood cell and platelet antigen genotyping platforms (ID CORE XT/ID HPA XT) in routine clinical practice.

PubMed

Finning, Kirstin; Bhandari, Radhika; Sellers, Fiona; Revelli, Nicoletta; Villa, Maria Antonietta; Muñiz-Díaz, Eduardo; Nogués, Núria

2016-03-01

High-throughput genotyping platforms enable simultaneous analysis of multiple polymorphisms for blood group typing. BLOODchip® ID is a genotyping platform based on Luminex® xMAP technology for simultaneous determination of 37 red blood cell (RBC) antigens (ID CORE XT) and 18 human platelet antigens (HPA) (ID HPA XT) using the BIDS XT software. In this international multicentre study, the performance of ID CORE XT and ID HPA XT, using the centres' current genotyping methods as the reference for comparison, and the usability and practicality of these systems, were evaluated under working laboratory conditions. DNA was extracted from whole blood in EDTA with Qiagen methodologies. Ninety-six previously phenotyped/genotyped samples were processed per assay: 87 testing samples plus five positive controls and four negative controls. Results were available for 519 samples: 258 with ID CORE XT and 261 with ID HPA XT. There were three "no calls" that were either caused by human error or resolved after repeating the test. Agreement between the tests and reference methods was 99.94% for ID CORE XT (9,540/9,546 antigens determined) and 100% for ID HPA XT (all 4,698 alleles determined). There were six discrepancies in antigen results in five RBC samples, four of which (in VS, N, S and Do(a)) could not be investigated due to lack of sufficient sample to perform additional tests and two of which (in S and C) were resolved in favour of ID CORE XT (100% accuracy). The total hands-on time was 28-41 minutes for a batch of 16 samples. Compared with the reference platforms, ID CORE XT and ID HPA XT were considered simpler to use and had shorter processing times. ID CORE XT and ID HPA XT genotyping platforms for RBC and platelet systems were accurate and user-friendly in working laboratory settings.

77 FR 10665 - General Services Administration Acquisition Regulation; Acquisition-Related Thresholds

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... GENERAL SERVICES ADMINISTRATION 48 CFR Parts 519 and 552 [GSAR Amendment 2012-02; GSAR Case 2011-G502; (Change 54) Docket 2012- 0003, Sequence 1] RIN 3090-AJ24 General Services Administration Acquisition Regulation; Acquisition-Related Thresholds AGENCIES: Office of Acquisition Policy, General...

76 FR 61366 - Food and Drug Administration Transparency Initiative: Draft Proposals for Public Comment to...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0247] Food and Drug Administration Transparency Initiative: Draft Proposals for Public Comment to Increase...: Food and Drug Administration, HHS. [[Page 61367

76 FR 5375 - Public Availability of General Services Administration FY 2010 Service Contract Inventory

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

... GENERAL SERVICES ADMINISTRATION [2011-MV-1; Docket No. 2011-0006; Sequence 4] Public Availability of General Services Administration FY 2010 Service Contract Inventory AGENCY: Office of Acquisition Policy; General Services Administration (GSA). ACTION: Notice. SUMMARY: This notice announces that GSA is...

78 FR 52531 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-07; Docket No. 2013-0002; Sequence 24] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting Notice. SUMMARY: The...

77 FR 5253 - Public Availability of General Services Administration FY 2011 Service Contract Inventory

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

... GENERAL SERVICES ADMINISTRATION [Notice-MV-2012-01; Docket 2012-0002; Sequence 3] Public Availability of General Services Administration FY 2011 Service Contract Inventory AGENCY: Office of Acquisition Policy (MV); General Services Administration (GSA). ACTION: Notice of public availability of FY...

78 FR 45200 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-26

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-06; Docket No. 2013-0002; Sequence 22] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting Notice. SUMMARY: The...

78 FR 64942 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-30

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-10; Docket No. 2013-0002; Sequence 32] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-Wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting notice. SUMMARY: The...

78 FR 34384 - The President's Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-07

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-04; Docket No. 2013-0002; Sequence 19] The President's Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting Notice. SUMMARY: The...

78 FR 55079 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-09

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-08; Docket No. 2013-0002; Sequence 27] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meetings AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting notice. SUMMARY: The...

78 FR 38042 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-25

... GENERAL SERVICES ADMINISTRATION [Notice--MK-2013-05; Docket No. 2013-0002; Sequence 20] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting; Correction AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting notice...

77 FR 54917 - Public Availability of General Services Administration FY 2012 Federal Activities Inventory...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... GENERAL SERVICES ADMINISTRATION [Notice-MV-2012-02; Docket No. 2012-0002; Sequence 14] Public Availability of General Services Administration FY 2012 Federal Activities Inventory Reform (FAIR) Act Inventory AGENCY: General Services Administration (GSA). ACTION: Notice of Public Availability of Fiscal...

76 FR 60822 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticides... perform its intended function without unreasonable adverse effects on human health or the environment... knowledge, including its effects on human health and the environment. EPA is also announcing that the docket...

76 FR 9771 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF11-5-000] Western Area Power Administration; Notice of Filing Take notice that on February 7, 2011, the Western Area Power Administration submitted a notice of complete cancellation of its baseline tariff filed on September 30, 2010, to...

75 FR 25869 - The National Institutes of Health and the Food and Drug Administration Joint Leadership Council...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-10

... comments to the Division of Dockets Management (HFA- 305), Food and Drug Administration, 5630 Fishers Lane..., an ever-changing economic landscape resulting from globalization, and the prospect for fundamental... Dockets Management (see ADDRESSES) written or electronic comments. Submit a single copy of electronic...

77 FR 21784 - Science Board to the Food and Drug Administration; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No FDA-2012-N-0001] Science Board to the Food and Drug Administration; Notice of Meeting AGENCY: Food and Drug Administration... Food and Drug Administration (FDA). The meeting will be open to the public. Name of Committee: Science...

75 FR 11893 - Food and Drug Administration Transparency Task Force; Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0247... Administration, HHS. ACTION: Notice; request for comments. SUMMARY: The Food and Drug Administration (FDA) is soliciting comments from interested persons on ways in which FDA can increase transparency between FDA and...

75 FR 38114 - [Docket ID FEMA-2010-0008

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

...: 1660-NEW. Form Titles and Numbers: FEMA Form FEMA Form 091-0, Homeland Security Exercise and Evaluation...; Existing collection in use without an OMB control number; OMB No. 1660-NEW; FEMA Form FEMA Form 091-0...] Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No. 1660-NEW...

78 FR 35272 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-12

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-05; Docket No. 2013-0002; Sequence 20] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-wide Policy, U.S. General Services Administration (GSA). ACTION: M eeting notice. SUMMARY: The...

78 FR 10174 - Public Availability of General Services Administration FY 2012 Service Contract Inventory

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-13

... GENERAL SERVICES ADMINISTRATION [Notice-MV-2013-02; Docket No. 2013-0002; Sequence 3] Public Availability of General Services Administration FY 2012 Service Contract Inventory AGENCY: General Services Administration (GSA). ACTION: Notice of Public Availability of FY 2012 Service Contract Inventories. SUMMARY: In...

76 FR 78933 - Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The...

76 FR 17138 - Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The...

75 FR 14448 - Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001] Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good Clinical Practices; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop...

78 FR 69416 - The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

... GENERAL SERVICES ADMINISTRATION [Notice-MK-2013-11; Docket No. 2013-0002; Sequence No. 36] The Presidential Commission on Election Administration (PCEA); Upcoming Public Advisory Meeting AGENCY: Office of Government-Wide Policy, U.S. General Services Administration (GSA). ACTION: Meeting Notice. SUMMARY: The...

39 CFR 3002.11 - Administrative Office.

Code of Federal Regulations, 2012 CFR

2012-07-01

... administration in conjunction with the Personnel Officer of a personnel program designed to meet the needs of the... electronic reading room accessible on the Commission's website at www.prc.gov. The information available on the Commission's website is, in general, coextensive with that available from the Commission's docket...

39 CFR 3002.11 - Administrative Office.

Code of Federal Regulations, 2011 CFR

2011-07-01

... administration in conjunction with the Personnel Officer of a personnel program designed to meet the needs of the... electronic reading room accessible on the Commission's website at www.prc.gov. The information available on the Commission's website is, in general, coextensive with that available from the Commission's docket...

76 FR 71498 - Periodic Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-18

... methodological changes approved in Proposal Twelve. Id. at 14. These methodological changes include the use of... study and models for Return Receipt service were developed in 1976 and updated in Docket Nos. MC96-3, R2000-1, and R2001-1. Id. \\7\\ Id. at 21; Docket No. ACR2010, USPS-FY10-28, FY 2010 Special Cost Studies...

77 FR 3836 - Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-25

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2011-0105] Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2011 Service Contract Inventories. SUMMARY: In accordance with...

78 FR 6168 - Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2013-0001] Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2012 Service Contract Inventories. SUMMARY: In accordance with...

75 FR 5166 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA 2009-0043] Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration/Railroad Retirement Board (SSA/RRB))-- Match Number 1308 AGENCY: Social Security Administration (SSA). ACTION: Notice of renewal of an existing...

78 FR 73863 - Public Availability of General Services Administration FY 2013 Federal Activities Inventory...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

... GENERAL SERVICES ADMINISTRATION [Notice-MV-2013-03; Docket No. 2013-0002; Sequence 37] Public... Inventory AGENCY: General Services Administration (GSA). ACTION: Notice of public availability of FY 2013...) Circular A-76, General Services Administration (GSA) is publishing this notice to advise the public of the...

77 FR 42082 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GUILDING LIGHT; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012 0079] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GUILDING LIGHT; Invitation for Public Comments AGENCY... GUILDING LIGHT is: [[Page 42083

78 FR 32214 - Land Acquisitions: Appeals of Land Acquisition Decisions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

...; 134D0102DR-DS5A300000-DR.5A311.IA000113; Docket ID: BIA-2013-0005] RIN 1076-AF15 Land Acquisitions: Appeals... trust under this part, including broadening notice of any right to file an administrative appeal. DATES... the United States acquired title. See, e.g., Neighbors for Rational Dev., Inc. v. Norton, 379 F.3d 956...

77 FR 5020 - General Services Administration Acquisition Regulation; Information Collection; GSA Form 527...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... GENERAL SERVICES ADMINISTRATION [OMB Control No. 3090-0007; Docket 2011-0001; Sequence 12] General Services Administration Acquisition Regulation; Information Collection; GSA Form 527, Contractor's Qualifications and Financial Information AGENCY: Office of the Chief Finance Officer, GSA. ACTION: Notice of...

Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma

DOEpatents

Desprez, Pierre-Yves; Campisi, Judith

2014-09-30

A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a delivery vehicle comprising a product which modulates Id-1 or Id-2 expression.

75 FR 73984 - Amendments to General Regulations of the Food and Drug Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 1, 14, and 17 [Docket No. FDA-2010-N-0560] RIN 0910-AG55 Amendments to General Regulations of the Food and Drug Administration AGENCY: Food and Drug Administration, HHS. ACTION: Proposed rule. SUMMARY: The Food and Drug...

75 FR 13766 - Food and Drug Administration and Process Analytical Technology for Pharma Manufacturing: Food and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

... Administration--Partnering With Industry; Public Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. The Food and Drug Administration (FDA) is announcing a joint conference with... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001...

75 FR 73107 - Guidance for Industry and Food and Drug Administration Staff; Blood Lancet Labeling; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0590] Guidance for Industry and Food and Drug Administration Staff; Blood Lancet Labeling; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is...

78 FR 14557 - Guidance for Industry and Food and Drug Administration Staff: Investigational Device Exemption...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-D-0010] Guidance for Industry and Food and Drug Administration Staff: Investigational Device Exemption Guidance for Retinal Prostheses; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The...

77 FR 49449 - Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001] Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food...

76 FR 25358 - 2011 Parenteral Drug Association/Food and Drug Administration Glass Quality Conference; Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] 2011 Parenteral Drug Association/Food and Drug Administration Glass Quality Conference; Public Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food...

77 FR 49448 - Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001] Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food...

76 FR 72953 - Science Board to the Food and Drug Administration; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No: FDA-2011-N-0002] Science Board to the Food and Drug Administration; Notice of Meeting AGENCY: Food and Drug Administration... pace with technical and scientific evolutions in the fields of regulatory science, on formulating an...

77 FR 40069 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0563... Labeled for Human Use; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing its intention to take enforcement...

7 CFR 1944.412 - Docket preparation.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.412 Docket... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... Fair Housing Marketing Plan 3 1 1-O and 1C 1-C Certified Copy Authorizing Resolution 1 1 1-O - Self...

78 FR 21120 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Acts...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... Constitution Ave. NW., Washington, DC 20460-0001. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is (202... the visitor instructions and additional information about the docket available at http://www.epa.gov...

78 FR 46287 - Administrative Revisions to EPAAR

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-31

..., such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov Federal Register, or in hard... administrative formating error with ``Alternate l''. 31. 1552.232-74 is amended to add ``Contracting Officer's...

Hobbins v. Attorney General; People v. Kevorkian (Docket No. 171056); People v. Kevorkian (Docket No. 172399).

PubMed

1994-05-10

In 1994, Michigan's Court of Appeals was asked to rule on three circuit court decisions involving Michigan's statute criminalizing assisted suicide and violations of the statute by Jack Kevorkian, M.D. The cases, consolidated on appeal, were Hobbins v. Attorney General, wherein the assisted suicide statute was declared unconstitutional; People v. Kevorkian (Docket No. 171056), wherein charges that Kevorkian had violated the statute by assisting in a suicide were dismissed; and People v. Kevorkian (Docket No. 172399), wherein additional charges that Kevorkian had violated the statute by assisting in another suicide were dismissed. In declaring the Michigan statute unconstitutional, two of the three circuit court judges held that individuals had a constitutional right to commit suicide. The Court of Appeals affirmed that the statute was unconstitutional because, by creating a commission to study end-of-life issues as well as specifically criminalizing assisted suicide, it violated the one-object provision of the Michigan Constitution. The court held, however, that there is no constitutional right to suicide, reversing the two circuit court orders in this respect.

A comparison of intellectual assessments over video conferencing and in-person for individuals with ID: preliminary data.

PubMed

Temple, V; Drummond, C; Valiquette, S; Jozsvai, E

2010-06-01

Video conferencing (VC) technology has great potential to increase accessibility to healthcare services for those living in rural or underserved communities. Previous studies have had some success in validating a small number of psychological tests for VC administration; however, VC has not been investigated for use with persons with intellectual disabilities (ID). A comparison of test results for two well known and widely used assessment instruments was undertaken to establish if scores for VC administration would differ significantly from in-person assessments. Nineteen individuals with ID aged 23-63 were assessed once in-person and once over VC using the Wechsler Abbreviated Scale of Intelligence (WASI) and the Beery-Buktenica Test of Visual-Motor Integration (VMI). Highly similar results were found for test scores. Full-scale IQ on the WASI and standard scores for the VMI were found to be very stable across the two administration conditions, with a mean difference of less than one IQ point/standard score. Video conferencing administration does not appear to alter test results significantly for overall score on a brief intelligence test or a test of visual-motor integration.

The Antibody Response of Pregnant Cameroonian Women to VAR2CSA ID1-ID2a, a Small Recombinant Protein Containing the CSA-Binding Site

PubMed Central

Babakhanyan, Anna; Leke, Rose G. F.; Salanti, Ali; Bobbili, Naveen; Gwanmesia, Philomina; Leke, Robert J. I.; Quakyi, Isabella A.; Chen, John J.; Taylor, Diane Wallace

2014-01-01

In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally acquire antibodies to ID1-ID2a and if antibodies to ID1-ID2a correlate with absence of placental malaria at delivery. Antibody levels to full-length VAR2CSA and ID1-ID2a were measured in plasma samples from 745 pregnant Cameroonian women, 144 Cameroonian men, and 66 US subjects. IgM levels and IgG avidity to ID1-ID2a were also determined. As expected, antibodies to ID1-ID2a were absent in US controls. Although pregnant Cameroonian women developed increasing levels of antibodies to full-length VAR2CSA during pregnancy, no increase in either IgM or IgG to ID1-ID2a was observed. Surprisingly, no differences in antibody levels to ID1-ID2a were detected between Cameroonian men and pregnant women. For example, in rural settings only 8–9% of males had antibodies to full-length VAR2CSA, but 90–96% had antibodies to ID1-ID2a. In addition, no significant difference in the avidity of IgG to ID1-ID2a was found between pregnant women and Cameroonian men, and no correlation between antibody levels at delivery and absence of placental malaria was found. Thus, the response to ID1-ID2a was not pregnancy specific, but predominantly against cross-reactivity epitopes, which may have been induced by other PfEMP1 antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a. PMID:24505415

Evaluation of ID-PaGIA syphilis antibody test.

PubMed

Naaber, Paul; Makoid, Ene; Aus, Anneli; Loivukene, Krista; Poder, Airi

2009-01-01

Laboratory diagnosis of syphilis is usually accomplished by serology. There are currently a large number of different commercial treponemal tests available that vary in format, sensitivity and specificity. To evaluate the ID-PaGIA Syphilis Antibody Test as an alternative to other specific treponemal tests for primary screening or confirmation of diagnosis. Serum samples from healthy adults (n = 100) were used for detection of specificity of ID-PaGIA. To evaluate sensitivity of ID-PaGIA serum samples (n = 101) from patients with confirmed or suspected syphilis were tested for syphilis antibodies with FTA-Abs IgM, ID-PaGIA, ELISA IgM and TPHA tests. No false-positive results were found with ID-PaGIA. Sensitivity of various treponemal tests was the following: FTA-Abs IgM: 95.5%, ID-PaGIA and ELISA IgM: 94%, and TPHA 75%. The positive and negative predictive values of ID-PaGIA were 100 and 89.5%, respectively. Compared with other treponemal tests ID-PaGIA has excellent sensitivity and specificity.

75 FR 73951 - Amendments to General Regulations of the Food and Drug Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 1, 14, and 17 [Docket No. FDA-2010-N-0560] RIN 0910-AG55 Amendments to General Regulations of the Food and Drug Administration AGENCY: Food and Drug Administration, HHS. ACTION: Direct final rule. SUMMARY: The Food and Drug...

77 FR 74913 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA 2012-0055] Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA)/Office of Personnel Management (OPM))--Match Number 1307 AGENCY: Social Security Administration. ACTION: Notice of a renewal of an existing...

78 FR 76842 - Food and Drug Administration/American Academy of Ophthalmology Workshop on Developing Novel...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

... for Premium Intraocular Lenses; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice. The Food and Drug Administration (FDA) is announcing the following public workshop entitled ``FDA... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001...

78 FR 54901 - Food and Drug Administration/American Academy of Ophthalmology Workshop on Developing Novel...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... for Premium Intraocular Lenses; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food and Drug Administration (FDA) is announcing the following public... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001...

33 CFR 148.207 - How and where may I view docketed documents?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Docket Management System Web site at http://www.dot.dms.gov. The projects are also listed by name and the assigned docket number at the G-PSO-5 Web site: http://www.uscg.mil/hq/g-m/mso/mso5.htm. ...

77 FR 11798 - Federal Housing Administration (FHA) Risk Management Initiatives: Revised Seller Concessions...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Chapter II [Docket No. FR-5572-C-02] Federal Housing Administration (FHA) Risk Management Initiatives: Revised Seller Concessions; Addresses for the... Administration (FHA) Risk Management Initiatives: Revised Seller Concessions). 1. Submission of Comments by Mail...

Vanillin improves scopolamine-induced memory impairment through restoration of ID1 expression in the mouse hippocampus

PubMed Central

Lee, Jae-Chul; Kim, In Hye; Cho, Jeong Hwi; Lee, Tae-Kyeong; Park, Joon Ha; Ahn, Ji Hyeon; Shin, Bich Na; Yan, Bing Chun; Kim, Jong-Dai; Jeon, Yong Hwan; Lee, Young Joo; Won, Moo-Ho; Kang, Il Jun

2018-01-01

4-Hydroxy-3-methoxybenzaldehyde (vanillin), contained in a number of species of plant, has been reported to display beneficial effects against brain injuries. In the present study, the impact of vanillin on scopolamine-induced alterations in cognition and the expression of DNA binding protein inhibitor ID-1 (ID1), one of the inhibitors of DNA binding/differentiation proteins that regulate gene transcription, in the mouse hippocampus. Mice were treated with 1 mg/kg scopolamine with or without 40 mg/kg vanillin once daily for 4 weeks. Scopolamine-induced cognitive impairment was observed from 1 week and was deemed to be severe 4 weeks following the administration of scopolamine. However, treatment with vanillin in scopolamine-treated mice markedly attenuated cognitive impairment 4 weeks following treatment with scopolamine. ID1-immunoreactive cells were revealed in the hippocampus of vehicle-treated mice, and were hardly detected 4 weeks following treatment with scopolamine. However, treatment with vanillin in scopolamine-treated mice markedly restored ID1-immunoreactive cells and expression 4 weeks subsequent to treatment. The results of the present study suggested that vanillin may be beneficial for cognitive impairment, by preventing the reduction of ID1 expression which may be associated with cognitive impairment. PMID:29328430

[Expression of Id1 and Id3 in endometrial carcinoma and their roles in regulating biological behaviors of endometrial carcinoma cells in vitro].

PubMed

Sun, Lili; Li, Xuenong; Liu, Guobing

2013-06-01

To investigate the expression of inhibitor of DNA differentiation/DNA binding 1 (Id1) and Id3 in endometrial carcinoma and explore their roles in regulating the proliferation, invasion, migration and adhesion of endometrial carcinoma cells in vitro. Id1 and Id3 expression in 4 fresh endometrial cancer tissue specimens and matched adjacent tissues were detected using Western blotting. Two endometrial cancer cell lines, HEC-1-B and RL-952, were both divided into 4 groups, namely the untreated group, blank virus group, promoter group and Id1/Id3 double-knockdown group, and their expressions of MMP2, CXCR4 and P21 were detected by qRT-PCR and Western blotting. The proliferation, invasion, migration and adhesion of the cells were evaluated with MTT, Transwell, wound-healing, and adhesion assays. Endometrial carcinoma tissues showed significantly higher Id1 and Id3 expression than the adjacent tissues (P<0.05). In the two endometrial carcinoma cell lines, Id1/Id3 double-knockdown significantly decreased MMP2 and CXCR4 expression and increased P21 expression at both mRNA and protein levels (P<0.05), and resulted in suppressed cell proliferation, invasion, migration and adhesion. Id1 and Id3 expressions are up-regulated in endometrial carcinoma to promote the proliferation, invasion, migration and adhesion of the tumor cells by increasing MMP2 and CXCR4 expression and reducing P21 expression. Therapies targeting Id1/Id3 can be a novel strategy for treatment of endometrial carcinoma.

77 FR 59611 - Notice of Receipt of Pesticide Products; Registration Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-28

... Symbol: 85004-RN. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc., 12085 Research Dr., Suite 185, Alachua, FL 32615. Active ingredient: Nematicide with Pasteuria spp. (Hoplolaimus... Symbol: 85004-RR. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc., 12085...

76 FR 789 - Guidance for Industry and Food and Drug Administration Staff; Section 905(j) Reports...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0635] Guidance for Industry and Food and Drug Administration Staff; Section 905(j) Reports: Demonstrating Substantial Equivalence for Tobacco Products; Availability AGENCY: Food and Drug Administration, HHS. ACTION...

75 FR 47603 - Draft Guidance for Industry and Food and Drug Administration Staff; Recommendations for Premarket...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0395] Draft Guidance for Industry and Food and Drug Administration Staff; Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays; Availability AGENCY: Food and Drug Administration, HHS...

76 FR 50740 - Draft Guidance for Industry and Food and Drug Administration Staff; Procedures for Handling...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0514] Draft Guidance for Industry and Food and Drug Administration Staff; Procedures for Handling Section 522 Postmarket Surveillance Studies; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

77 FR 55845 - Science Board to the Food and Drug Administration: Request for Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001... Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is requesting nominations to serve on the Science Board to FDA (Science Board). FDA seeks to include the views of women and men...

78 FR 277 - Food and Drug Administration Actions Related to Nicotine Replacement Therapies and Smoking...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

... Dependence; Public Hearing; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notification of public hearing; Extension of comment period. SUMMARY: The Food and Drug Administration (FDA) is... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 15 [Docket No...

75 FR 28205 - Administrative Waivers of the Coastwise Trade Laws: New Definition for Eligible Vessel

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-20

... Administration (MARAD) is changing the definition of ``eligible vessel'' to be considered for a waiver of the... DEPARTMENT OF TRANSPORTATION Maritime Administration 46 CFR Part 388 [Docket No. MARAD 2010 0012] RIN 2133-AB76 Administrative Waivers of the Coastwise Trade Laws: New Definition for Eligible Vessel...

77 FR 26001 - Southwest Power Pool; Western Area Power Administration; Basin Electric Cooperative; Heartland...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-60-000] Southwest Power Pool; Western Area Power Administration; Basin Electric Cooperative; Heartland Consumers Power District... 385.207, Southwest Power Pool (SPP), Western Area Power Administration (Western), Basin Electric Power...

78 FR 44574 - Third Annual Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-24

... . Contact: Brenda Rose, Office of Special Health Issues, 10903 New Hampshire Ave., Silver Spring, MD 20993... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001] Third Annual Food and Drug Administration Health Professional Organizations Conference AGENCY: Food and...

R&D100: IC ID

ScienceCinema

Hamlet, Jason; Pierson, Lyndon; Bauer, Todd

2018-06-25

Supply chain security to detect, deter, and prevent the counterfeiting of networked and stand-alone integrated circuits (ICs) is critical to cyber security. Sandia National Laboratory researchers have developed IC ID to leverage Physically Unclonable Functions (PUFs) and strong cryptographic authentication to create a unique fingerprint for each integrated circuit. IC ID assures the authenticity of ICs to prevent tampering or malicious substitution.

76 FR 9027 - Draft Guidance for Industry and Food and Drug Administration Staff on Best Practices for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0057] Draft Guidance for Industry and Food and Drug Administration Staff on Best Practices for Conducting and...: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is...

77 FR 52744 - Food and Drug Administration/European Medicines Agency Orphan Product Designation and Grant Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001] Food and Drug Administration/European Medicines Agency Orphan Product Designation and Grant Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of meeting. The Food and Drug Administration's (FDA) Office of Orphan Products Development...

78 FR 6673 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-30

... include alternative testing options for certain large spark ignition (generally natural gas-fueled... action under Docket ID No. EPA-HQ-OAR-2008-0708. The EPA also relies on materials in Docket ID Nos. EPA... Business Information or other information whose disclosure is restricted by statute. Certain other material...

78 FR 25530 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HOWLIN AT THE MOON...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0050] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HOWLIN AT THE MOON; Invitation for Public Comments... HOWLIN AT THE MOON is: [[Page 25531

76 FR 30727 - Food and Drug Administration Food Safety Modernization Act: Focus on Inspections and Compliance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0366] Food and Drug Administration Food Safety Modernization Act: Focus on Inspections and Compliance AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public meeting; request for comments. SUMMARY: The...

75 FR 48699 - Memorandum of Understanding Between United States Food and Drug Administration and the Centers...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-11

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004] [FDA 225-10-0010] Memorandum of Understanding Between United States Food and Drug Administration and the Centers for Medicare and Medicaid Services AGENCY: Food and Drug Administration, HHS. ACTION...

78 FR 5185 - Guidance for Industry and Food and Drug Administration Staff; Humanitarian Use Device (HUD...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0847] Guidance for Industry and Food and Drug Administration Staff; Humanitarian Use Device (HUD) Designations... public comment ``Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian Use...

75 FR 29561 - Memorandum of Understanding Between the Food and Drug Administration and Drugs.Com

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004] [FDA 225-09-0012] Memorandum of Understanding Between the Food and Drug Administration and Drugs.Com... Administration (FDA) is providing notice of a memorandum of understanding (MOU) between FDA and Drugs.Com. The...

Administrative Record Introduction, American Drum & Pallet Co. Removal Site, Memphis, Shelby County, Tennessee

EPA Pesticide Factsheets

Introduction to a document that contains the Index to and the Administrative Record for the American Drum & Pallet Co. Removal Site, Memphis, Shelby County, Tennessee. Region ID: 04 DocID: 10517014, DocDate: 08-17-2007

77 FR 31432 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PASSION; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0062] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PASSION; Invitation for Public Comments AGENCY... PASSION is: Intended Commercial Use of Vessel: ``Bareboat chartering, sailing classes.'' Geographic Region...

76 FR 75948 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CHRYSALIS; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0149] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CHRYSALIS; Invitation for Public Comments AGENCY... CHRYSALIS is: Intended Commercial Use of Vessel: ``Weekly charter vessel.'' Geographic Region: ``Florida...

77 FR 40146 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SATISFACTION; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0076] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SATISFACTION; Invitation for Public Comments AGENCY... SATISFACTION is: Intended Commercial Use of Vessel: ``Sightseeing, whale watching, snorkeling, and cruising...

77 FR 41415 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... INFORMATION CONTACT: Astrid Lopez-Goldberg, Center for Drug Evaluation and Research, Food and Drug... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0563] Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration and...

77 FR 47652 - Second Annual Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-09

... of Special Health Issues, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD... between health professional organizations and FDA staff. The Office of Special Health Issues serves as a... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001...

46 CFR 502.271 - Special docket application for permission to refund or waive freight charges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 9 2010-10-01 2010-10-01 false Special docket application for permission to refund or... docket application for permission to refund or waive freight charges. (a)(1) A common carrier or a shipper may file a special docket application seeking permission for a common carrier or conference to...

75 FR 1050 - Western Area Power Administration; Notice of Filing

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2010-01-08

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-2-000] Western Area Power Administration; Notice of Filing December 30, 2009. Take notice that on December 16, 2009, the Deputy Secretary of the [[Page 1051

77 FR 14403 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0167] Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document: Norovirus Serological Reagents; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

78 FR 39061 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MISTRESS MALLIKA; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0076] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MISTRESS MALLIKA; Invitation for Public Comments AGENCY... MISTRESS MALLIKA is: Intended Commercial Use Of Vessel: ``Pleasure Charters''. Geographic Region: Rhode...

78 FR 25529 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ALCHEMY; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0048] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ALCHEMY; Invitation for Public Comments AGENCY... ALCHEMY is: Intended Commercial Use of Vessel: ``Uninspected six-pack sailing charters and instruction...

78 FR 25531 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel TEMPEST; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0046] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel TEMPEST; Invitation for Public Comments AGENCY... TEMPEST is: Intended Commercial Use of Vessel: ``Offshore wreck diving.'' Geographic Region: Maine, New...

78 FR 47825 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SERENITY; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0091] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SERENITY; Invitation for Public Comments AGENCY... SERENITY is: Intended Commercial Use of Vessel: ``Coastwise charters, Sight seeing tours, sunset and...

78 FR 14586 - Agency Information Collection Activities: Application for Civil Surgeon Designation Registration...

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2013-03-06

... include the OMB Control Number 1615-0114 in the subject box, the agency name and Docket ID USCIS-XXXX- XXXX. To avoid duplicate submissions, please use only one of the following methods to submit comments... e-Docket ID number USCIS-XXXX-XXXX; (2) Email. Submit comments to [email protected] ; (3...

77 FR 41186 - Proposed Consent Decree, Clean Air Act Citizen Suit

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2012-07-12

... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OGC-2012-0554; FRL-9699-6] Proposed Consent Decree, Clean... August 13, 2012. ADDRESSES: Submit your comments, identified by Docket ID number EPA-HQ- OGC-2012-0554... (identified by Docket ID No. EPA-HQ-OGC-2012-0554) contains a copy of the proposed consent decree. The...

77 FR 36583 - NRC Form 5, Occupational Dose Record for a Monitoring Period

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2012-06-19

... methods: Federal Rulemaking Web site: Go to http://www.regulations.gov and search for Docket ID NRC-2012... following methods: Federal Rulemaking Web Site: Go to http://www.regulations.gov and search for Docket ID... begin the search, select ``ADAMS Public Documents'' and then select ``Begin Web- based ADAMS Search...

IDS contribution to ITRF2008

NASA Astrophysics Data System (ADS)

Valette, Jean-Jacques; Lemoine, Frank G.; Ferrage, Pascale; Yaya, Philippe; Altamimi, Zuheir; Willis, Pascal; Soudarin, Laurent

2010-12-01

For the first time, the International DORIS Service (IDS) has produced a technique level combination based on the contributions of seven analysis centers (ACs), including the European Space Operations Center (ESOC), Geodetic Observatory Pecny (GOP), Geoscience Australia (GAU), the NASA Goddard Space Flight Center (GSFC), the Institut Géographique National (IGN), the Institute of Astronomy, Russian Academy of Sciences (INASAN, named as INA), and CNES/CLS (named as LCA). The ACs used five different software packages to process the DORIS data from 1992 to 2008, including NAPEOS (ESA), Bernese (GOP), GEODYN (GAU, GSC), GIPSY/OASIS (INA), and GINS (LCA). The data from seven DORIS satellites, TOPEX/Poseidon, SPOT-2, SPOT-3, SPOT-4, SPOT-5, Envisat and Jason-1 were processed and all the analysis centers produced weekly SINEX files in either variance-covariance or normal equation format. The processing by the analysis centers used the latest GRACE-derived gravity models, forward modelling of atmospheric gravity, updates to the radiation pressure modelling to improve the DORIS geocenter solutions, denser parameterization of empirically determined drag coefficients to improve station and EOP solutions, especially near the solar maximum in 2001-2002, updated troposphere mapping functions, and an ITRF2005-derived station set for orbit determination, DPOD2005. The CATREF software was used to process the weekly AC solutions, and produce three iterations of an IDS global weekly combination. Between the development of the initial solution IDS-1, and the final solution, IDS-3, the ACs improved their analysis strategies and submitted updated solutions to eliminate troposphere-derived biases in the solution scale, to reduce drag-related degradations in station positioning, and to refine the estimation strategy to improve the combination geocenter solution. An analysis of the frequency content of the individual AC geocenter and scale solutions was used as the basis to define the

78 FR 6824 - Considerations Regarding Food and Drug Administration Review and Regulation of Drugs for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

... Amyotrophic Lateral Sclerosis; Public Hearing AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public hearing; request for comments. SUMMARY: The Food and Drug Administration (FDA or the Agency) is... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0035...

78 FR 51732 - The Food and Drug Administration/European Medicines Agency Orphan Product Designation and Grant...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001] The Food and Drug Administration/European Medicines Agency Orphan Product Designation and Grant Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food and Drug...

76 FR 6477 - Industry Exchange Workshop on Food and Drug Administration Drug and Device Requirements; Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Industry Exchange Workshop on Food and Drug Administration Drug and Device Requirements; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. SUMMARY: The Food and Drug...

75 FR 74063 - Supplemental Funding Under the Food and Drug Administration's Convener of Active Medical Product...

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2010-11-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0576] Supplemental Funding Under the Food and Drug Administration's Convener of Active Medical Product Surveillance Discussions (U13) RFA- FD-09-012; Request for Supplemental Application AGENCY: Food and Drug Administration...

77 FR 67820 - Privacy Act of 1974; Report of a New System of Records; Food and Drug Administration User Fee System

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-14

..., timely account disablement/deletion, configuration management, maintenance, system and information... paper or CD-ROM submissions): Division of Dockets Management (HFA-305), Food and Drug Administration... document, into the ``Search'' box and follow the prompts and/or go to the Division of Dockets Management...

ID-based encryption scheme with revocation

NASA Astrophysics Data System (ADS)

Othman, Hafizul Azrie; Ismail, Eddie Shahril

2017-04-01

In 2015, Meshram proposed an efficient ID-based cryptographic encryption based on the difficulty of solving discrete logarithm and integer-factoring problems. The scheme was pairing free and claimed to be secure against adaptive chosen plaintext attacks (CPA). Later, Tan et al. proved that the scheme was insecure by presenting a method to recover the secret master key and to obtain prime factorization of modulo n. In this paper, we propose a new pairing-free ID-based encryption scheme with revocation based on Meshram's ID-based encryption scheme, which is also secure against Tan et al.'s attacks.

78 FR 20172 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BASIC INSTINCT; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0037] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BASIC INSTINCT; Invitation for Public Comments AGENCY... BASIC INSTINCT is: Intended Commercial Use Of Vessel: Charters for day excursions. Geographic Region...

78 FR 46410 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel IMPOSSIBLE DREAM; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0084] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel IMPOSSIBLE DREAM; Invitation for Public Comments AGENCY... of the vessel IMPOSSIBLE DREAM is: Intended Commercial Use of Vessel: ``Day, Multiple Day, Week...

78 FR 15017 - Guidance for Industry: What You Need To Know About Administrative Detention of Foods; Small...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0643... Compliance Guide; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled...

76 FR 77542 - Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian Use Device...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0847] Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian Use Device Designations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and...

76 FR 51993 - Draft Guidance for Industry and Food and Drug Administration Staff on In Vitro Companion...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-19

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0215] Draft Guidance for Industry and Food and Drug Administration Staff on In Vitro Companion Diagnostic Devices; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notice; extension...

76 FR 36543 - Draft Guidance for Industry and Food and Drug Administration Staff: Applying Human Factors and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0469] Draft Guidance for Industry and Food and Drug Administration Staff: Applying Human Factors and Usability Engineering To Optimize Medical Device Design; Availability AGENCY: Food and Drug Administration, HHS. ACTION...

78 FR 14305 - Draft Guidance for Industry and Food and Drug Administration Staff; Types of Communication During...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-0147] Draft Guidance for Industry and Food and Drug Administration Staff; Types of Communication During the Review of Medical Device Submissions; Availability AGENCY: Food and Drug Administration, HHS. ACTION...

77 FR 41413 - Draft Guidance for Industry and Food and Drug Administration Staff; Medical Devices: The Pre...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0530... Program and Meetings With FDA Staff; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of the draft...

FEDFacts: Information about the Federal Electronic Docket Facilities

EPA Pesticide Factsheets

Cleanup status information related to Federal Facilities contained in EPA's Federal Agency Hazardous Waste Compliance Docket. Information includes maps, lists of facilities, dashboard view with graphs, links to community resources, and news items.

Previous Federal Agency Hazardous Waste Compliance Docket Updates

EPA Pesticide Factsheets

The Federal Agency Hazardous Waste Compliance Docket contains information reported to EPA by federal facilities that manage hazardous waste or from which hazardous substances, pollutants, or contaminants have been - or may be - released.

77 FR 46128 - Proposed Revision 0 to Standard Review Plan Section 19.5: Adequacy of Design Features and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-02

... searching on http://www.regulations.gov under Docket ID NRC-2012-0180. You may submit comments by any of the following methods: Federal rulemaking Web site: Go to http://www.regulations.gov and search for Docket ID..., Policy Branch, Division of Advanced Reactors and Rulemaking, Office of New Reactors, U.S. Nuclear...

76 FR 38150 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... ID No. EPA-HQ-OEI- 2011-0096, to (1) EPA online using http://www.regulations.gov (our preferred... a public docket for this ICR under Docket ID No. EPA-HQ-OEI-2011-0096, which is available for online..., technology-neutral framework for electronic reporting across all EPA programs; allow EPA programs to offer...

29 CFR 501.38 - Notice of docketing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Notice of docketing. 501.38 Section 501.38 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

29 CFR 502.38 - Notice of docketing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Notice of docketing. 502.38 Section 502.38 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

75 FR 17418 - Memorandum of Understanding Between the Food and Drug Administration, United States Department of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004] Memorandum of Understanding Between the Food and Drug Administration, United States Department of Health and... understanding (MOU) between the Food and Drug Administration, U.S. Department of Health and Human Services and...

49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

Code of Federal Regulations, 2014 CFR

2014-10-01

... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's official public docket files of its accident investigations, or its computerized accident database(s) shall be...

49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

Code of Federal Regulations, 2012 CFR

2012-10-01

... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's official public docket files of its accident investigations, or its computerized accident database(s) shall be...

49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

Code of Federal Regulations, 2010 CFR

2010-10-01

... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's official public docket files of its accident investigations, or its computerized accident database(s) shall be...

49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

Code of Federal Regulations, 2013 CFR

2013-10-01

... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's official public docket files of its accident investigations, or its computerized accident database(s) shall be...

49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

Code of Federal Regulations, 2011 CFR

2011-10-01

... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's official public docket files of its accident investigations, or its computerized accident database(s) shall be...

76 FR 79764 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel DREAM CATCHER; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0156] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel DREAM CATCHER; Invitation for Public Comments AGENCY... DREAM CATCHER is: INTENDED COMMERCIAL USE OF VESSEL: ``Passenger charter.'' GEOGRAPHIC REGION: ``Georgia...

77 FR 20100 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel NORDIC STAR; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012 0039] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel NORDIC STAR; Invitation for Public Comments AGENCY... NORDIC STAR is: Intended Commercial Use of Vessel: ``Sailing excursions and extended charters...

76 FR 67254 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ABOUT TIME; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0136] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ABOUT TIME; Invitation for Public Comments AGENCY... ABOUT TIME is: INTENDED COMMERCIAL USE OF VESSEL: ``Uninspected passenger vessel.'' GEOGRAPHIC REGION...

78 FR 19066 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MI CASA; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0035] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MI CASA; Invitation for Public Comments AGENCY... CASA is: Intended Commercial Use of Vessel: Passenger charters. Geographic Region: Massachusetts, New...

78 FR 70096 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE MOON; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0129] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE MOON; Invitation for Public Comments AGENCY... MOON is: Intended Commercial Use of Vessel: ``Bareboat Charter'' Geographic Region: ``Maine, Maryland...

77 FR 35743 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND CHANCE; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0067] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND CHANCE; Invitation for Public Comments AGENCY... SECOND CHANCE is: Intended Commercial Use of Vessel: ``Small group charters.'' Geographic Region...

78 FR 35092 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEAR BOAT; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0069] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEAR BOAT; Invitation for Public Comments AGENCY... BOAT is: Intended Commercial Use of Vessel: ``Crewed and unscrewed (bareboat) sailboat charters...

76 FR 64354 - Burden of Food and Drug Administration Food Safety Modernization Act Fee Amounts on Small...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-18

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0529] Burden of Food and Drug Administration Food Safety Modernization Act Fee Amounts on Small Business; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notice; extension of comment...

78 FR 9928 - Food and Drug Administration Drug Shortages Task Force and Strategic Plan; Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0124] Food and Drug Administration Drug Shortages Task Force and Strategic Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice; request for comments. SUMMARY: To assist the Food...

49 CFR 601.44 - Posting to the docket.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 24 hours a day, seven days a week, via the Internet at the docket facility's Web site at http://dms... or subgrantee needs to request immediate relief and does not have access to electronic means to...

Multimodal biometrics for identity documents (MBioID).

PubMed

Dessimoz, Damien; Richiardi, Jonas; Champod, Christophe; Drygajlo, Andrzej

2007-04-11

The MBioID initiative has been set up to address the following germane question: What and how biometric technologies could be deployed in identity documents in the foreseeable future? This research effort proposes to look at current and future practices and systems of establishing and using biometric identity documents (IDs) and evaluate their effectiveness in large-scale developments. The first objective of the MBioID project is to present a review document establishing the current state-of-the-art related to the use of multimodal biometrics in an IDs application. This research report gives the main definitions, properties and the framework of use related to biometrics, an overview of the main standards developed in the biometric industry and standardisation organisations to ensure interoperability, as well as some of the legal framework and the issues associated to biometrics such as privacy and personal data protection. The state-of-the-art in terms of technological development is also summarised for a range of single biometric modalities (2D and 3D face, fingerprint, iris, on-line signature and speech), chosen according to ICAO recommendations and availabilities, and for various multimodal approaches. This paper gives a summary of the main elements of that report. The second objective of the MBioID project is to propose relevant acquisition and evaluation protocols for a large-scale deployment of biometric IDs. Combined with the protocols, a multimodal database will be acquired in a realistic way, in order to be as close as possible to a real biometric IDs deployment. In this paper, the issues and solutions related to the acquisition setup are briefly presented.

77 FR 56264 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HAPPY ENDINGS; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0090] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HAPPY ENDINGS; Invitation for Public Comments AGENCY... of the vessel HAPPY ENDINGS is: Intended Commercial Use of Vessel: ``Sunset, day and overnight...

77 FR 5628 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BIG GAME; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0003] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BIG GAME; Invitation for Public Comments AGENCY... GAME is: Intended Commercial Use of Vessel: ``Fishing charter boat.'' Geographic Region: ``Rhode Island...

78 FR 25530 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE DOLPHIN; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0049] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE DOLPHIN; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BLUE...

78 FR 76406 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COSMO; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0142] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COSMO; Invitation for Public Comments AGENCY: Maritime... COSMO is: Intended Commercial Use Of Vessel: ``Day sail charters and lessons.'' Geographic Region: ``New...

78 FR 35093 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel EYE DOC; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0071] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel EYE DOC; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel EYE...

78 FR 53004 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2013 0093] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for Public Comments AGENCY... SECOND WIND is: Intended Commercial Use of Vessel: ``Breakfast, lunch, and dinner cruises featuring...

78 FR 70097 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEE; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0128] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEE; Invitation for Public Comments AGENCY: Maritime....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BEE...

78 FR 23823 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA HAG; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0042] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA HAG; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SEA...

78 FR 8698 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COOL BEANS; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0005] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COOL BEANS; Invitation for Public Comments AGENCY... BEANS is: Intended Commercial Use of Vessel: Sightseeing and sunset cruises. Geographic Region: Florida...

78 FR 42153 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-15

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0081] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for Public Comments AGENCY... COMPASS ROSE is: Intended Commercial Use Of Vessel: ``Sailboat charters six passengers or less...

76 FR 67253 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE GIFT; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0131] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE GIFT; Invitation for Public Comments AGENCY... GIFT is: INTENDED COMMERCIAL USE OF VESSEL: ``Passenger carrying.'' GEOGRAPHIC REGION: ``ME, NH, MA, RI...

77 FR 26818 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FREE SPIRIT; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0058] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FREE SPIRIT; Invitation for Public Comments AGENCY... SPIRIT is: Intended Commercial Use of Vessel: ``Day/overnight passenger passage. Depart and return same...

77 FR 74274 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MELLO MOON; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-13

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0110] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MELLO MOON; Invitation for Public Comments AGENCY... of the vessel MELLO MOON is: Intended Commercial Use of Vessel: ``Six pack passenger charters...

77 FR 10802 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SILVER MOON; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0012] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SILVER MOON; Invitation for Public Comments AGENCY... SILVER MOON is: Intended Commercial Use of Vessel: ``Catamaran Sailing Charters, both term and day...

78 FR 76403 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel JAGUAR; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0146] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel JAGUAR; Invitation for Public Comments AGENCY: Maritime... JAGUAR is: Intended Commercial Use Of Vessel: ``For bare boat/lease recreational use.'' Geographic Region...

76 FR 70216 - Requested Administrative Waiver of the Coastwise Trade Laws; Vessel REEL ATTITUDE; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0146] Requested Administrative Waiver of the Coastwise Trade Laws; Vessel REEL ATTITUDE; Invitation for Public Comments AGENCY... ATTITUDE is: Intended Commercial Use of Vessel: ``Fishing Charter passenger less than 6.'' Geographic...

78 FR 40265 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HMS-DISCOVERY; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0077] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HMS-DISCOVERY; Invitation for Public Comments AGENCY... of the vessel HMS-DISCOVERY is: Intended Commercial Use of Vessel: ``Sight Seeing Tours''. Geographic...

78 FR 33150 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLACK ICE; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0063] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLACK ICE; Invitation for Public Comments AGENCY... BLACK ICE is: Intended Commercial Use Of Vessel: Small passenger sails. Sightseeing, dinner sails...

75 FR 31450 - Memorandum of Understanding by and Between the United States Food and Drug Administration and the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... Administration and the International Anesthesia Research Society for the Safety of Key Inhaled and Intravenous Drugs in Pediatrics Public-Private Partnership AGENCY: Food and Drug Administration, HHS. ACTION: Notice... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004...

78 FR 36711 - Food and Drug Administration Safety and Innovation Act Title VII-Drug Supply Chain; Standards for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-19

...: Food and Drug Administration, HHS. ACTION: Notification of public meeting; request for comments. SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing a public meeting regarding FDA's... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Chapter I [Docket Nos...

78 FR 28228 - Guidance for Industry and Food and Drug Administration Staff on Best Practices for Conducting and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0057] Guidance for Industry and Food and Drug Administration Staff on Best Practices for Conducting and Reporting Pharmacoepidemiologic Safety Studies Using Electronic Healthcare Data; Availability AGENCY: Food and Drug Administration...

77 FR 5027 - Food and Drug Administration Transparency Initiative: Exploratory Program To Increase Access to...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0247] Food and Drug Administration Transparency Initiative: Exploratory Program To Increase Access to the... responsible for a broad range of compliance and enforcement activities. Increasing the transparency of these...

77 FR 24271 - Federal Plan Requirements for Hospital/Medical/Infectious Waste Incinerators Constructed on or...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

... a-and-r[email protected] , Attention Docket ID No. EPA-HQ-OAR-2011-0405. Facsimile: Fax your comments... electronic mail to a-and-r[email protected] , Attention Docket ID No. EPA-HQ-OAR-2006-0534. Facsimile: Fax your....regulations.gov Web site is an ``anonymous access'' system, which means the EPA will not know your identity or...

39 CFR 3020.73 - Docket and notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Docket and notice. 3020.73 Section 3020.73 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PRODUCT LISTS Proposal of the Commission To Modify the... Web site. The notice shall include: (a) The general nature of the proceeding; (b) A reference to legal...

39 CFR 3020.33 - Docket and notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Docket and notice. 3020.33 Section 3020.33 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PRODUCT LISTS Requests Initiated by the Postal Service To... on its Web site. The notice shall include: (a) The general nature of the proceeding; (b) A reference...

76 FR 67255 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KIWI CAT; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0135] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KIWI CAT; Invitation for Public Comments AGENCY... CAT is: INTENDED COMMERCIAL USE OF VESSEL: ``Small vessel 12 person chartering service for the San...

78 FR 23823 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FISHIN GAME; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0043] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FISHIN GAME; Invitation for Public Comments AGENCY... FISHIN GAME is: Intended Commercial Use Of Vessel: Sport fishing excursions with six passengers or less...

78 FR 13752 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GATO; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0012] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GATO; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel GATO is: Intended...

78 FR 37659 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ORCA; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-21

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0075] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ORCA; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel ORCA is: Intended...

77 FR 73735 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PREDATOR II; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-11

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0108] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PREDATOR II; Invitation for Public Comments AGENCY... of the vessel PREDATOR II is: Intended Commercial Use of Vessel: 6 pack private charters. Geographic...

78 FR 13751 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LAST TIME AROUND; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0015] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LAST TIME AROUND; Invitation for Public Comments AGENCY... TIME AROUND is: Intended Commercial Use Of Vessel: ``Chartering for day or week'' Geographic Region...

78 FR 13752 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0013] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SPIRIT is: Intended...

77 FR 22631 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0049] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SPIRIT is: Intended...

76 FR 76812 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BARBARY GHOST; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0148] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BARBARY GHOST; Invitation for Public Comments AGENCY... BARBARY GHOST is: Intended Commercial Use Of Vessel: ``Sightseeing tours in the San Francisco Bay for a...

78 FR 14413 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LUCKY DUCK; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0019] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LUCKY DUCK; Invitation for Public Comments AGENCY... LUCKY DUCK is: Intended Commercial Use Of Vessel: ``The vessel is to be operated as a sailing...

78 FR 30961 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LITTLE DUTCH; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0057] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LITTLE DUTCH; Invitation for Public Comments AGENCY... LITTLE DUTCH is: Intended Commercial Use of Vessel: ``Carrying up to six passengers for day trips, sunset...

77 FR 26819 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE PLANET; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0054] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE PLANET; Invitation for Public Comments AGENCY... PLANET is: Intended Commercial use of Vessel: ``Charter to Boy Scouts of America Florida Sea Base...

78 FR 15019 - Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0196] Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice, request for comments. SUMMARY: The Food and...

75 FR 18219 - Drug and Medical Device Forum on Food and Drug Administration Drug and Device Requirements and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0142] Drug and Medical Device Forum on Food and Drug Administration Drug and Device Requirements and Supplier Controls; Public Educational Forum AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public...

78 FR 102 - Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical Device...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-1056] Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical Device Submissions; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug...

77 FR 11550 - Draft Guidance for Industry on Notification to Food and Drug Administration of Issues That May...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0140] Draft Guidance for Industry on Notification to Food and Drug Administration of Issues That May Result in a Prescription Drug Shortage; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

75 FR 21000 - Draft Guidance for the Public, Food and Drug Administration Advisory Committee Members, and Food...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-22

...] (formerly Docket No. 02D-0049) Draft Guidance for the Public, Food and Drug Administration Advisory Committee Members, and Food and Drug Administration Staff: Public Availability of Advisory Committee Members... and Drug Administration Amendments Act of 2007, Public Law No. 110-85), and section 701 (21 U.S.C. 371...

77 FR 56264 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel TREE OF LIFE; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0089] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel TREE OF LIFE; Invitation for Public Comments AGENCY... OF LIFE is: Intended Commercial Use of Vessel: ``Passenger carrying charter vessel.'' Geographic...

76 FR 76813 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FOR-2-NA; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0157] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FOR-2-NA; Invitation for Public Comments AGENCY...-2-NA is: Intended Commercial Use of Vessel: ``Charter fishing, for hire.'' Geographic Region...

76 FR 55927 - Draft Guidance for Industry and Food and Drug Administration Staff; Demonstrating the Substantial...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0147] Draft Guidance for Industry and Food and Drug Administration Staff; Demonstrating the Substantial Equivalence of a New Tobacco Product: Responses to Frequently Asked Questions; Availability AGENCY: Food and...

77 FR 11553 - Draft Guidance on Food and Drug Administration Oversight of Positron Emission Tomography Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0080... Food and Drug Administration (FDA) is announcing the availability of a draft guidance entitled ``FDA... that address nearly all aspects of the FDA approval and surveillance processes, including application...

77 FR 71803 - Guidance on Food and Drug Administration Oversight of Positron Emission Tomography Drug Products...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0080... and Drug Administration (FDA) is announcing the availability of a guidance entitled ``FDA Oversight of... nearly all aspects of the FDA approval and surveillance processes, including application submission...

44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

Code of Federal Regulations, 2014 CFR

2014-10-01

... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal Insurance... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and...

44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

Code of Federal Regulations, 2012 CFR

2012-10-01

... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal Insurance... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and...

The Role of Id2 Protein in Neuroblatoma in Children.

PubMed

Wieczorek, Aleksandra; Balwierz, Walentyna

2015-09-01

Id (DNA binding and/or differentiation) proteins occur physiologically during ontogenesis and negatively regulate the activity of other helix-loop-helix (HLH) proteins. Id2 protein causes block of cells differentiation in the S phase of the cell cycle and regulates the activity of Rb protein. The role of Id2 protein in physiological cell cycle progression and in neuroblastoma (NBL) pathogenesis was proposed by Lasorella. The aim of the study was evaluation of Id2 expression and its prognostic significance in NBL cells coming from primary tumors and evaluation of its prognostic significance, and correlation of Id2 expression with known prognostic factors. Sixty patients with primary NBL treated from 1991 to 2005 were included in the analysis. We found 50 patients with high and 10 patients with low intensity of Id2 expression. The median percentage of NBL cells with Id2 expression was 88 %. We found no correlation between the number of NBL cells or the intensity of Id2 expression and OS and DFS. In patients with stage 4 NBL, almost all patients had high expression of Id2 and it was significantly more common than in other disease stages (p = 0,03). We found no correlation between Id2 expression and other known prognostic factor in NBL patients. We assume that Id2 is not prognostic factor. However, due to its abundant expression in most of NBL cells and its role in cell cycle, it may be potential therapeutic target. Exact knowledge of expression time may be helpful in explaining mechanisms of oncogenesis.

78 FR 25433 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF13-5-000] Western Area Power Administration; Notice of Filing Take notice that on April 24, 2013, the Secretary of the Department of Energy submitted its Rate Order No. WAPA-160 concerning extension of Washoe Project, Stampede...

75 FR 62531 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-7-000] Western Area Power Administration; Notice of Filing October 1, 2010. Take notice that on September 16, 2010, the Deputy Secretary of the Department of Energy, under the authority vested in the Federal Energy Regulatory...

78 FR 19068 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GOLDEN BOY II; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0036] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GOLDEN BOY II; Invitation for Public Comments AGENCY... GOLDEN BOY II is: Intended Commercial Use Of Vessel: Limited charter of passengers for luxury day...

78 FR 39062 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA BREEZE 27; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0079] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA BREEZE 27; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SEA...

77 FR 26820 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE BLUE MOON; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0055] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE BLUE MOON; Invitation for Public Comments AGENCY... BLUE MOON is: Intended Commercial Use of Vessel: ``6 pack UPV (short cruises).'' Geographic Region...

76 FR 43690 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2007-D-0149] (Formerly 2007D-0309) Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document: Electrocardiograph Electrodes; Availability AGENCY: Food and Drug...

77 FR 66911 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FIVE O'CLOCK HERE; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0102] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FIVE O'CLOCK HERE; Invitation for Public Comments... O'CLOCK HERE is: Intended Commercial Use of Vessel: ``Day and overnight charters in California...

75 FR 63462 - Smart Grid Interoperability Standards; Notice of Docket Designation for Smart Grid...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RM11-2-000] Smart Grid Interoperability Standards; Notice of Docket Designation for Smart Grid Interoperability Standards October 7, 2010... directs the development of a framework to achieve interoperability of smart grid devices and systems...

77 FR 35745 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SMOKE AND ROSES; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0068] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SMOKE AND ROSES; Invitation for Public Comments AGENCY... SMOKE AND ROSES is: INTENDED COMMERCIAL USE OF VESSEL: ``We intend to carry up to 10 passengers for hire...

77 FR 66832 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... ICR under docket ID number EPA-HQ-OECA-2012-0505, which is available for public viewing online at http://www.regulations.gov , or in person viewing at the Enforcement and Compliance Docket in the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Avenue NW., Washington, DC. The EPA Docket Center...

75 FR 1052 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-3-000] Western Area Power Administration; Notice of Filing December 30, 2009. Take notice that on December 23, 2009, the Deputy Secretary of the Department of Energy submitted Rate Order Nos. WAPA-144 and WAPA-148, confirmed...

75 FR 1050 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-1-000] Western Area Power Administration; Notice of Filing December 30, 2009. Take notice that on December 16, 2009, the Deputy Secretary of the Department of Energy submitted Rate Order No. WAPA-146, confirmed and approved on...

78 FR 25434 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF13-4-000] Western Area Power Administration; Notice of Filing Take notice that on April 4, 2013, the Deputy Secretary of the Department of Energy submitted its Rate Order No. WAPA-157 concerning rate adjustment for the Pacific...

78 FR 9396 - Draft Guidance for Industry and Food and Drug Administration Staff; Civil Money Penalties for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-1083] Draft Guidance for Industry and Food and Drug Administration Staff; Civil Money Penalties for Tobacco... guidance for industry entitled ``Civil Money Penalties for Tobacco Retailers: Responses to Frequently Asked...

78 FR 72900 - Guidance for Industry and Food and Drug Administration Staff; Civil Money Penalties for Tobacco...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-1083] Guidance for Industry and Food and Drug Administration Staff; Civil Money Penalties for Tobacco Retailers... the guidance entitled ``Civil Money Penalties for Tobacco Retailers: Responses to Frequently Asked...

78 FR 19362 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0026] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel W.L...

78 FR 9701 - Draft Joint Food and Drug Administration/Health Canada Quantitative Assessment of the Risk of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... on the sources of L. monocytogenes contamination, the effects of individual manufacturing and/or... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-1182] Draft Joint Food and Drug Administration/Health Canada Quantitative Assessment of the Risk of...

75 FR 59726 - Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-28

... method comparison section and the sample selection inclusion and exclusion criteria section. The... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0428] Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

76 FR 48870 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

... selection inclusion and exclusion criteria section. The revisions define and differentiate the required... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0428] Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document...

77 FR 21150 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SIR MARTIN II; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-09

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0047] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SIR MARTIN II; Invitation for Public Comments AGENCY... the vessel SIR MARTIN II is: Intended Commercial Use of Vessel: ``Day charter up to 6 passengers for...

78 FR 39342 - SHINE Medical Technologies, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-01

... NUCLEAR REGULATORY COMMISSION [Docket No. 50-608; NRC-2013-0053] SHINE Medical Technologies, Inc... Technologies, Inc., is acceptable for docketing. ADDRESSES: Please refer to Docket ID NRC-2013-0053 when...: [email protected] . SUPPLEMENTARY INFORMATION: On March 26, 2013, SHINE Medical Technologies (SHINE...

75 FR 17423 - Memorandum of Understanding Between the Food and Drug Administration, United States Department of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004] [FDA 225-10-0007] Memorandum of Understanding Between the Food and Drug Administration, United States...) is providing notice of a memorandum of understanding (MOU) between the FDA, U.S. Department of Health...

76 FR 36133 - Draft Guidances for Industry and Food and Drug Administration Staff: Classification of Products...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0429] Draft Guidances for Industry and Food and Drug Administration Staff: Classification of Products as Drugs... Action'' in the Definition of Device Under Section 201(h) of the Federal Food, Drug, and Cosmetic Act...

76 FR 22905 - Guidance for Food and Drug Administration Staff and Tobacco Retailers on Civil Money Penalties...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-25

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0431] Guidance for Food and Drug Administration Staff and Tobacco Retailers on Civil Money Penalties and No... entitled ``Civil Money Penalties and No- Tobacco-Sale Orders for Tobacco Retailers.'' This guidance...

75 FR 53316 - Draft Guidance for Food and Drug Administration Staff and Tobacco Retailers on Civil Money...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-31

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0431] Draft Guidance for Food and Drug Administration Staff and Tobacco Retailers on Civil Money Penalties and... guidance entitled ``Civil Money Penalties and No-Tobacco-Sale Orders for Tobacco Retailers.'' This guidance...

75 FR 9202 - Western Area Power Administration; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EF10-5-000] Western Area Power Administration; Notice of Filing February 19, 2010. Take notice that on February 2, 2010, the... Commission by Delegation Order No. 00-037.00, submitted Rate Order No. WAPA-149, the power rate formula for...

18 CFR 385.2006 - Docket system (Rule 2006).

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Docket system (Rule 2006). 385.2006 Section 385.2006 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... availability is consistent with the proper discharge of the Commission's duties and in conformity with part 388...

77 FR 73396 - Proposed Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-10

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-B-1089] Proposed Flood Elevation Determinations AGENCY.... ADDRESSES: You may submit comments, identified by Docket No. FEMA-B- 1089, to Luis Rodriguez, Chief...

77 FR 73398 - Proposed Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-10

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-B-1085] Proposed Flood Elevation Determinations AGENCY..., identified by Docket No. FEMA-B- 1085, to Luis Rodriguez, Chief, Engineering Management Branch, Federal...

77 FR 66791 - Proposed Flood Elevation Determinations for Wicomico County, MD, and Incorporated Areas

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-B-1085] Proposed Flood Elevation Determinations for Wicomico..., identified by Docket No. FEMA-B- 1085, to Luis Rodriguez, Chief, Engineering Management Branch, Federal...

77 FR 73393 - Proposed Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-10

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-B-1085] Proposed Flood Elevation Determinations AGENCY..., identified by Docket No. FEMA-B- 1085, to Luis Rodriguez, Chief, Engineering Management Branch, Federal...

Enhanced ID Pit Sizing Using Multivariate Regression Algorithm

NASA Astrophysics Data System (ADS)

Krzywosz, Kenji

2007-03-01

EPRI is funding a program to enhance and improve the reliability of inside diameter (ID) pit sizing for balance-of plant heat exchangers, such as condensers and component cooling water heat exchangers. More traditional approaches to ID pit sizing involve the use of frequency-specific amplitude or phase angles. The enhanced multivariate regression algorithm for ID pit depth sizing incorporates three simultaneous input parameters of frequency, amplitude, and phase angle. A set of calibration data sets consisting of machined pits of various rounded and elongated shapes and depths was acquired in the frequency range of 100 kHz to 1 MHz for stainless steel tubing having nominal wall thickness of 0.028 inch. To add noise to the acquired data set, each test sample was rotated and test data acquired at 3, 6, 9, and 12 o'clock positions. The ID pit depths were estimated using a second order and fourth order regression functions by relying on normalized amplitude and phase angle information from multiple frequencies. Due to unique damage morphology associated with the microbiologically-influenced ID pits, it was necessary to modify the elongated calibration standard-based algorithms by relying on the algorithm developed solely from the destructive sectioning results. This paper presents the use of transformed multivariate regression algorithm to estimate ID pit depths and compare the results with the traditional univariate phase angle analysis. Both estimates were then compared with the destructive sectioning results.

75 FR 34464 - Memorandum of Understanding Between the Food and Drug Administration and Drugs.Com; Correction of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-17

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004] FDA 225-09-0012 Memorandum of Understanding Between the Food and Drug Administration and Drugs.Com... date of the memorandum of understanding (MOU) between FDA and Drugs.Com that published in the Federal...

76 FR 16425 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-23

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76 FR 13700 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... day charters on Chesapeake Bay and tributaries and Delaware Bay for team building exercises, hands-on... represented by the Maritime Administration (MARAD), is authorized to grant waivers of the U.S.-build... Clerk, U.S. Department of Transportation, Docket Operations, M-30, West Building Ground Floor, Room W12...

78 FR 16184 - Revision to Ambient Nitrogen Dioxide Monitoring Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-14

... Revision to Ambient Nitrogen Dioxide Monitoring Requirements AGENCY: Environmental Protection Agency (EPA... ambient air quality standard (NAAQS) for nitrogen dioxide (NO 2 ) for the near-road component of the NO 2... Nitrogen Dioxide Monitoring Requirements Docket, Docket ID No. EPA-HQ-OAR-2012- 0486, EPA Docket Center...

76 FR 13571 - Proposed Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2008-0020; Internal Agency Docket No. FEMA-B-1072] Proposed Flood Elevation Determinations AGENCY... June 13, 2011. ADDRESSES: You may submit comments, identified by Docket No. FEMA-B- 1072, to Luis...

76 FR 74791 - Memorandum of Understanding Between the Food and Drug Administration and the U.S. Department of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0005] Memorandum of Understanding Between the Food and Drug Administration and the U.S. Department of Agriculture's... memorandum of understanding (MOU) with the U.S. Department of Agriculture's (USDA) Agricultural and Marketing...

75 FR 32952 - Draft Guidance for Industry and Food and Drug Administration Staff; “‘Harmful and Potentially...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-10

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0281] Draft Guidance for Industry and Food and Drug Administration Staff; ```Harmful and Potentially Harmful... Food, Drug, and Cosmetic Act.'' This draft guidance provides written guidance to industry and FDA staff...

Microbe-ID: an open source toolbox for microbial genotyping and species identification

PubMed Central

Tabima, Javier F.; Everhart, Sydney E.; Larsen, Meredith M.; Weisberg, Alexandra J.; Kamvar, Zhian N.; Tancos, Matthew A.; Smart, Christine D.; Chang, Jeff H.

2016-01-01

Development of tools to identify species, genotypes, or novel strains of invasive organisms is critical for monitoring emergence and implementing rapid response measures. Molecular markers, although critical to identifying species or genotypes, require bioinformatic tools for analysis. However, user-friendly analytical tools for fast identification are not readily available. To address this need, we created a web-based set of applications called Microbe-ID that allow for customizing a toolbox for rapid species identification and strain genotyping using any genetic markers of choice. Two components of Microbe-ID, named Sequence-ID and Genotype-ID, implement species and genotype identification, respectively. Sequence-ID allows identification of species by using BLAST to query sequences for any locus of interest against a custom reference sequence database. Genotype-ID allows placement of an unknown multilocus marker in either a minimum spanning network or dendrogram with bootstrap support from a user-created reference database. Microbe-ID can be used for identification of any organism based on nucleotide sequences or any molecular marker type and several examples are provided. We created a public website for demonstration purposes called Microbe-ID (microbe-id.org) and provided a working implementation for the genus Phytophthora (phytophthora-id.org). In Phytophthora-ID, the Sequence-ID application allows identification based on ITS or cox spacer sequences. Genotype-ID groups individuals into clonal lineages based on simple sequence repeat (SSR) markers for the two invasive plant pathogen species P. infestans and P. ramorum. All code is open source and available on github and CRAN. Instructions for installation and use are provided at https://github.com/grunwaldlab/Microbe-ID. PMID:27602267

Microbe-ID: an open source toolbox for microbial genotyping and species identification.

PubMed

Tabima, Javier F; Everhart, Sydney E; Larsen, Meredith M; Weisberg, Alexandra J; Kamvar, Zhian N; Tancos, Matthew A; Smart, Christine D; Chang, Jeff H; Grünwald, Niklaus J

2016-01-01

Development of tools to identify species, genotypes, or novel strains of invasive organisms is critical for monitoring emergence and implementing rapid response measures. Molecular markers, although critical to identifying species or genotypes, require bioinformatic tools for analysis. However, user-friendly analytical tools for fast identification are not readily available. To address this need, we created a web-based set of applications called Microbe-ID that allow for customizing a toolbox for rapid species identification and strain genotyping using any genetic markers of choice. Two components of Microbe-ID, named Sequence-ID and Genotype-ID, implement species and genotype identification, respectively. Sequence-ID allows identification of species by using BLAST to query sequences for any locus of interest against a custom reference sequence database. Genotype-ID allows placement of an unknown multilocus marker in either a minimum spanning network or dendrogram with bootstrap support from a user-created reference database. Microbe-ID can be used for identification of any organism based on nucleotide sequences or any molecular marker type and several examples are provided. We created a public website for demonstration purposes called Microbe-ID (microbe-id.org) and provided a working implementation for the genus Phytophthora (phytophthora-id.org). In Phytophthora-ID, the Sequence-ID application allows identification based on ITS or cox spacer sequences. Genotype-ID groups individuals into clonal lineages based on simple sequence repeat (SSR) markers for the two invasive plant pathogen species P. infestans and P. ramorum. All code is open source and available on github and CRAN. Instructions for installation and use are provided at https://github.com/grunwaldlab/Microbe-ID.

Security analysis for biometric data in ID documents

NASA Astrophysics Data System (ADS)

Schimke, Sascha; Kiltz, Stefan; Vielhauer, Claus; Kalker, Ton

2005-03-01

In this paper we analyze chances and challenges with respect to the security of using biometrics in ID documents. We identify goals for ID documents, set by national and international authorities, and discuss the degree of security, which is obtainable with the inclusion of biometric into documents like passports. Starting from classical techniques for manual authentication of ID card holders, we expand our view towards automatic methods based on biometrics. We do so by reviewing different human biometric attributes by modality, as well as by discussing possible techniques for storing and handling the particular biometric data on the document. Further, we explore possible vulnerabilities of potential biometric passport systems. Based on the findings of that discussion we will expand upon two exemplary approaches for including digital biometric data in the context of ID documents and present potential risks attack scenarios along with technical aspects such as capacity and robustness.

76 FR 44594 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0465] Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document... guidance document will serve as the special control for rTMS systems. Section 513(f)(2) of the Federal Food...

Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-Occurring ASD and ID

ERIC Educational Resources Information Center

Schieve, Laura A.; Clayton, Heather B.; Durkin, Maureen S.; Wingate, Martha S.; Drews-Botsch, Carolyn

2015-01-01

While studies report associations between perinatal outcomes and both autism spectrum disorder (ASD) and intellectual disability (ID), there has been little study of ASD with versus without co-occurring ID. We compared perinatal risk factors among 7547 children in the 2006-2010 Autism and Developmental Disability Monitoring Network classified as…

Biolog(TM) ID as compared to 16S ribosomal RNA ID for environmental isolates from the deep subsurface

DOE Office of Scientific and Technical Information (OSTI.GOV)

McKinsey, P.C.

2000-05-05

The U.S. Dept of Energy (DOE) Subsurface Microbial Culture Collection (SMCC) contains nearly 10,000 strains of microorganisms isolated from terrestrial subsurface environments. Many of the aerobic, gram-negative, chemoheterotrophs isolated from the DOE Savannah River Site (SRS) have previously been identified by phylogenetic analysis of 16S ribosomal RNA (rRNA) gene nucleotide sequences. These SMCC isolates are currently being examined using Biolog GN Microplates and the Biolog Microstation System in order to gain knowledge of their metabolic capabilities and to compare Biolog IDs with 16S IDs. To accommodate the particular needs of these subsurface isolates, which are often incapable of growing undermore » high-nutrient conditions, Biolog's recommendations for inoculating isolates into Biolog GN Microplates have been altered. The isolates are grown on low nutrient media, sodium thioglycolate (3mM) is added to the culture media to inhibit capsule formation, and a low density of bacteria is inoculated into the microplate. Using these altered inoculation criteria, 60 percent of these SMCC isolates have a Biolog genus ID that matches the 16S rRNA ID. These results indicate that the Biolog System can be a good means of identifying unusual environmental isolates, even when recommended inoculation procedures are altered to accommodate particular isolate needs.« less

Priority Queuing on the Docket: Universality of Judicial Dispute Resolution Timing

NASA Astrophysics Data System (ADS)

Mukherjee, Satyam; Whalen, Ryan

2018-01-01

This paper analyzes court priority queuing behavior by examining the time lapse between when a case enters a court’s docket and when it is ultimately disposed of. Using data from the Supreme courts of the United States, Massachusetts, and Canada we show that each court’s docket features a slow decay with a decreasing tail. This demonstrates that, in each of the courts examined, the vast majority of cases are resolved relatively quickly, while there remains a small number of outlier cases that take an extremely long time to resolve. We discuss the implications for this on legal systems, the study of the law, and future research.

Novel ID-based anti-collision approach for RFID

NASA Astrophysics Data System (ADS)

Zhang, De-Gan; Li, Wen-Bin

2016-09-01

Novel correlation ID-based (CID) anti-collision approach for RFID under the banner of the Internet of Things (IOT) has been presented in this paper. The key insights are as follows: according to the deterministic algorithms which are based on the binary search tree, we propose a method to increase the association between tags so that tags can initiatively send their own ID under certain trigger conditions, at the same time, we present a multi-tree search method for querying. When the number of tags is small, by replacing the actual ID with the temporary ID, it can greatly reduce the number of times that the reader reads and writes to tag's ID. Active tags send data to the reader by the way of modulation binary pulses. When applying this method to the uncertain ALOHA algorithms, the reader can determine the locations of the empty slots according to the position of the binary pulse, so it can avoid the decrease in efficiency which is caused by reading empty slots when reading slots. Theory and experiment show that this method can greatly improve the recognition efficiency of the system when applied to either the search tree or the ALOHA anti-collision algorithms.

78 FR 57150 - Agency Information Collection Activities; Proposed Collection; Request for Comments on Three...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-17

... (Identify Docket ID No. EPA-HQ- OW-2008-0719 in the subject line). Mail: Water Docket, Environmental... or email. The www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will.../epahome/dockets.htm . FOR FURTHER INFORMATION CONTACT: Sandra Rivera, State and Regional Branch, Water...

77 FR 75039 - Propiconazole; Pesticide Tolerances

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

...- 671A) is available to enforce the tolerance expression. The method may be requested from: Chief... action, identified by docket identification (ID) number EPA-HQ-OPP-2011-0772, is available at http://www... additional information about the docket available at http://www.epa.gov/dockets . FOR FURTHER INFORMATION...

75 FR 66055 - Notice of Data Availability Supporting Federal Implementation Plans To Reduce Interstate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-27

... at the Air and Radiation Docket and Information Center, EPA/DC, EPA East Building, Room 3334, 1301... docket for the Proposed Transport Rule (Docket ID No. EPA-HQ-OAR-2009- 0491) additional information... emissions inventories for specific source categories and related new information and models that have become...

Chronic arsenic intoxication diagnostic score (CAsIDS).

PubMed

Dani, Sergio Ulhoa; Walter, Gerhard Franz

2018-01-01

Arsenic and its compounds are well-established, potent, environmentally widespread and persistent toxicants with metabolic, genotoxic, mutagenic, teratogenic, epigenetic and carcinogenic effects. Arsenic occurs naturally in the Earth's crust, but anthropogenic arsenic emissions have surmounted the emissions from important natural sources such as volcanism. Inorganic arsenicals exhibit acute and chronic toxicities in virtually all cell types and tissues, and hence arsenic intoxication affects multiple systems. Whereas acute arsenic intoxication is rare and relatively easy to diagnose, chronic arsenic intoxication (CAsI) is common but goes often misdiagnosed. Based on a review of the literature as well as our own clinical experience, we propose a chronic arsenic intoxication diagnostic score (CAsIDS). A distinctive feature of CAsIDS is the use of bone arsenic load as an essential criterion for the individual risk assessment of chronic arsenic intoxication, combined with a systemic clinical assessment. We present clinical examples where CAsIDS is applied for the diagnosis of CAsI, review the main topics of the toxicity of arsenic in different cell and organ systems and discuss the therapy and prevention of disease caused or aggravated by chronic arsenic intoxication. CAsIDS can help physicians establish the diagnosis of CAsI and associated conditions. Copyright © 2017 John Wiley & Sons, Ltd.

Virosomal hepatitis a vaccine: comparing intradermal and subcutaneous with intramuscular administration.

PubMed

Frösner, Gert; Steffen, Robert; Herzog, Christian

2009-01-01

Vaccination against hepatitis A virus (HAV) is unaffordable to many developing countries. Substantial reductions in cost occur when vaccines are administered intradermally at low doses. Aluminum-free HAV vaccines are considered more suitable for intradermal use than traditional vaccines which can cause long-lasting local reactions. Thus, we compared the immunogenicity and safety of an aluminum-free virosomal HAV vaccine (Epaxal) administered by different routes: intradermal (i.d.), subcutaneous (s.c.), and intramuscular (i.m.). Two open pilot studies were conducted as sub-studies of a large lot consistency trial. Healthy subjects aged 18 to 45 were enrolled. Study 1 compared two i.d. regimens of a lower dose of Epaxal [0.1 mL (4.8 IU), one or two injection sites] with i.m. administration of the standard dose [0.5 mL (24 IU)]. Study 2 compared the s.c. with the i.m. administration of the standard dose. At month 12, subjects in study 1 received a booster dose of 0.1 mL i.d. or 0.5 mL i.m.; subjects in study 2 received 0.5 mL via the respective route (s.c. or i.m.). Serum was tested for antibodies at baseline, 2 weeks (study 1), and 1 and 6 months after the primary vaccination as well as prior and 1 month after the booster dose. Incidences of solicited and unsolicited adverse events were recorded. Seroprotection rates (anti-HAV geometric mean concentration of > or =20 mIU/mL) after 1 month ranged from 93.2% to 100% in all groups and remained high until month 12 (range 85.2&-90.2%). Complete (100%) seroprotection was achieved by all subjects in all groups after booster vaccination. All routes of administration were well tolerated. Local reactions were more common in subjects vaccinated i.d. and s.c. than i.m. The aluminum-free virosomal HAV vaccine Epaxal is highly immunogenic and well tolerated when administered either via i.d., s.c., or i.m. Vaccination via the i.d. route may confer significant cost savings over the conventional i.m. route.

The ID23-2 structural biology microfocus beamline at the ESRF

PubMed Central

Flot, David; Mairs, Trevor; Giraud, Thierry; Guijarro, Matias; Lesourd, Marc; Rey, Vicente; van Brussel, Denis; Morawe, Christian; Borel, Christine; Hignette, Olivier; Chavanne, Joel; Nurizzo, Didier; McSweeney, Sean; Mitchell, Edward

2010-01-01

The first phase of the ESRF beamline ID23 to be constructed was ID23-1, a tunable MAD-capable beamline which opened to users in early 2004. The second phase of the beamline to be constructed is ID23-2, a monochromatic microfocus beamline dedicated to macromolecular crystallography experiments. Beamline ID23-2 makes use of well characterized optical elements: a single-bounce silicon (111) monochromator and two mirrors in Kirkpatrick–Baez geometry to focus the X-ray beam. A major design goal of the ID23-2 beamline is to provide a reliable, easy-to-use and routine microfocus beam. ID23-2 started operation in November 2005, as the first beamline dedicated to microfocus macromolecular crystallography. The beamline has taken the standard automated ESRF macromolecular crystallography environment (both hardware and software), allowing users of ID23-2 to be rapidly familiar with the microfocus environment. This paper describes the beamline design, the special considerations taken into account given the microfocus beam, and summarizes the results of the first years of the beamline operation. PMID:20029119

47 CFR 1.730 - The Enforcement Bureau's Accelerated Docket.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Docket proceedings, the Commission may conduct a minitrial, or hearing-type proceeding, as an alternative... receive a specific time allotment in which it may present evidence and make argument during the minitrial... allotment any time that the party spends presenting either evidence or argument during the proceeding. The...

75 FR 34782 - Exelon Generation Company, LLC, Braidwood Station, Independent Spent Fuel Installation Order...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

..., to request (1) a digital ID certificate, which allows the participant (or its counsel or... NRC- issued digital ID certificate). Based upon this information, the Secretary will establish an... electronic docket. Information about applying for a digital ID certificate is available on NRC's public Web...

75 FR 24998 - In the Matter of Florida Power and Light Company: Turkey Point Nuclear Plant; Independent Spent...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-06

..., to request (1) a digital ID certificate, which allows the participant (or its counsel or... NRC- issued digital ID certificate). Based upon this information, the Secretary will establish an... electronic docket. Information about applying for a digital ID certificate is available on NRC's public Web...

Fake ID ownership and heavy drinking in underage college students: prospective findings.

PubMed

Martinez, Julia A; Rutledge, Patricia C; Sher, Kenneth J

2007-06-01

The authors examined the ownership of false identification (fake ID) for the purpose of obtaining alcohol and the relation of fake ID ownership to heavy drinking in a longitudinal sample of college students under 21 years of age. A sample of 3,720 undergraduates was assessed the summer prior to college entrance and during the 4 semesters comprising freshman and sophomore years. Regression analyses were used to estimate bidirectional relations between consumption and fake ID ownership. Sex, Greek membership, and prior drinking were controlled. Results showed that fake ID ownership increased over time (12.5% pre-college to 32.2% fourth semester) and that Greek members were more likely than others to own fake IDs. Fake ID ownership predicted concurrent and next-semester heavy drinking with increasing strength over time. Also, the acquisition (onset) of fake ID ownership at each time point was predicted by previous-semester consumption. When traditional, robust risk factors of consumption are controlled, fake ID ownership meaningfully relates to heavy drinking in college. It thus presents a significant public health problem, addressable through training for alcohol servers and retailers, punitive measures toward fake ID owners, and other possible interventions.

78 FR 11589 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-19

... Docket ID no. EPA-HQ- SFUND-1990-0011, by one of the following methods: http://www.regulations.gov... received will be included in the public docket without change and may be made available online at http... is placed in the public docket and made available on the Internet. If you submit an electronic...

77 FR 56201 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... comments, referencing Docket ID No. EPA-HQ-OAR- 2003-0162, to (1) EPA online using www.regulations.gov (our... collecting, are available in the public docket for this ICR. The docket can be viewed online at www... actions conform with the SIP requirements. Depending on the type of action, the federal entities must...

Administrative Settlement Agreement and Order on Consent for Removal Action, in the Matter of: Forshaw Chemicals Site, Charlotte, Mecklenburg County, North Carolina, Forshaw Chemicals, Inc. Respondent, CERCLA DOCKET NO. 04-2009-3979

EPA Pesticide Factsheets

Contains legal agreement for the Forshaw Chemicals site under CERCLA Sections 104, 106(a), 107 and 122, Charlotte, Mecklenburg County, North Carolina, August 17, 2009 Region ID: 04 DocID: 10427285, DocDate: 08-17-2009

Infant and toddler disease score was useful for risk of hospitalization based on data from administrative claims.

PubMed

Mikaeloff, Yann; Moride, Yola; Khoshnood, Babak; Weill, Alain; Bréart, Gérard

2007-07-01

To develop the infant and toddler disease score (IDS), a population-based predictive tool of morbidity status in infants and toddlers, based on data from administrative claims. A prospective cohort study was conducted, including 35,580 children less than 2 years of age in June 2003 from the French "ERASME" database (mean follow-up 13 months). The outcome variable was incident hospitalization during the follow-up year, that is, before the second birthday for infants and before the third for toddlers. Risk factors before inclusion (age, health care use, medications) were assessed in a 50% random sample (construction sample) by a logistic regression model. Beta coefficients were summed up to obtain the IDS. The IDS was then validated for the remaining 50% of the study population (validation sample). The major variables significantly associated with the outcome were long-term disability, younger age, and >or=1 hospitalization before inclusion. The risks of hospitalization estimated by the IDS were concordant in the construction and validation samples. The IDS is a useful index for the risk of hospitalization of infants and toddlers in relation to their morbidity status and may be used for adjustment in pharmacoepidemiologic studies using administrative claims databases.

An online ID identification system for liquefied-gas cylinder plant

NASA Astrophysics Data System (ADS)

He, Jin; Ding, Zhenwen; Han, Lei; Zhang, Hao

2017-11-01

An automatic ID identification system for gas cylinders' online production was developed based on the production conditions and requirements of the Technical Committee for Standardization of Gas Cylinders. A cylinder ID image acquisition system was designed to improve the image contrast of ID regions on gas cylinders against the background. Then the ID digits region was located by the CNN template matching algorithm. Following that, an adaptive threshold method based on the analysis of local average grey value and standard deviation was proposed to overcome defects of non-uniform background in the segmentation results. To improve the single digit identification accuracy, two BP neural networks were trained respectively for the identification of all digits and the easily confusable digits. If the single digit was classified as one of confusable digits by the former BP neural network, it was further tested by the later one, and the later result was taken as the final identification result of this single digit. At last, the majority voting was adopted to decide the final identification result for the 6-digit cylinder ID. The developed system was installed on a production line of a liquefied-petroleum-gas cylinder plant and worked in parallel with the existing weighing step on the line. Through the field test, the correct identification rate for single ID digit was 94.73%, and none of the tested 2000 cylinder ID was misclassified through the majority voting.

77 FR 22777 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... Docket ID No. EPA-HQ-RCRA-2011-0890, which is available for online viewing at www.regulations.gov , or in person viewing at the Resource Conservation and Recovery Act (RCRA) Docket at the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Ave. NW., Washington, DC. The EPA/DC Public Reading Room...

77 FR 3262 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-23

... Docket ID No EPA-HQ-RCRA-2011-0624, which is available for online viewing at www.regulations.gov , or in person viewing at the Resource Conservation and Recovery Act (RCRA) Docket in the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Ave. NW., Washington, DC. The EPA/DC Public Reading Room...

77 FR 22571 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... Docket ID No EPA-HQ-RCRA-2011-0890, which is available for online viewing at www.regulations.gov , or in person viewing at the Resource Conservation and Recovery Act (RCRA) Docket at the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Ave. NW., Washington, DC. The EPA/DC Public Reading Room...

76 FR 54223 - Notice of Proposed Administrative Cost Recovery Settlement Pursuant to the Comprehensive...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-31

... Costs Incurred at Marine Corps Logistics Base Barstow, CA AGENCY: Department of the Navy, DoD. ACTION... Logistics Base, Yermo Annex, Barstow, California, DON CERCLA Administrative Docket No. 2011-0001, pertaining to environmental contamination at the Marine Corps Logistics Base in Barstow, California (the ``Site...

77 FR 43846 - Food and Drug Administration Pediatric Medical Devices Workshop; Notice of Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0001... Products Development is announcing the following workshop: FDA Pediatric Medical Devices Workshop. This meeting is intended to focus on challenges in pediatric device development--namely, business planning and...

78 FR 36277 - Vogtle Electric Generating Plant, Unit 3

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... NUCLEAR REGULATORY COMMISSION [Docket No. 52-025; NRC-2008-0252] Vogtle Electric Generating Plant....01, for the Vogtle Electric Generating Plant, Unit 3. ADDRESSES: Please refer to Docket ID NRC-2008... Generating Plant, Unit 3 [[Page 36278

RGSS-ID: an approach to new radiologic reporting system.

PubMed

Ikeda, M; Sakuma, S; Maruyama, K

1990-01-01

RGSS-ID is a developmental computer system that applies artificial intelligence (AI) methods to a reporting system. The representation scheme called Generalized Finding Representation (GFR) is proposed to bridge the gap between natural language expressions in the radiology report and AI methods. The entry process of RGSS-ID is made mainly by selecting items; our system allows a radiologist to compose a sentence which can be completely parsed by the computer. Further RGSS-ID encodes findings into the expression corresponding to GFR, and stores this expression into the knowledge data base. The final printed report is made in the natural language.

Enabling OpenID Authentication for VO-integrated Portals

NASA Astrophysics Data System (ADS)

Plante, R.; Yekkirala, V.; Baker, W.

2012-09-01

To support interoperating services that share proprietary data and other user-specific information, the VAO Project provides login services for browser-based portals built on the open standard, OpenID. To help portal developers take advantage of this service, we have developed a downloadable toolkit for integrating OpenID single sign-on support into any portal. This toolkit provides APIs in a few languages commonly used on the server-side as well as a command-line version for use in any language. In addition to describing how to use this toolkit, we also discuss the general VAO framework for single sign-on. While a portal may, if it wishes, support any OpenID provider, the VAO service provides a few extra features to support VO interoperability. This includes a portal's ability to retrieve (with the user's permission) an X.509 certificate representing the authenticated user so that the portal can access other restricted services on the user's behalf. Other standard features of OpenID allow portals to request other information about the user; this feature will be used in the future for sharing information about a user's group membership to enable sharing within a group of collaborating scientists.

14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

Code of Federal Regulations, 2010 CFR

2010-01-01

... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive security...

78 FR 40142 - Office of Managing Director Creates Docket for Petitions Seeking Review of Application Fee Refund...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... FEDERAL COMMUNICATIONS COMMISSION [MD Docket No. 13-163; DA 13-1400] Office of Managing Director... Communications Commission. ACTION: Notice. SUMMARY: The Office of Managing Director has created the new docket..., Federal Communications Commission, Financial Management Specialist, Office of the Managing Director, 445...

14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

Code of Federal Regulations, 2014 CFR

2014-01-01

... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive security...

14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

Code of Federal Regulations, 2012 CFR

2012-01-01

... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive security...

14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

Code of Federal Regulations, 2013 CFR

2013-01-01

... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive security...

14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

Code of Federal Regulations, 2011 CFR

2011-01-01

... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive security...

78 FR 22490 - Administrative Practice and Procedure; Postal Service; Review of Price Cap Rules

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

...] Administrative Practice and Procedure; Postal Service; Review of Price Cap Rules AGENCY: Postal Regulatory Commission. ACTION: Proposed rule. SUMMARY: The Commission is initiating a review of its Price Cap Rules. The... implemented without a price cap calculation. Docket No. R2011-5, Order Approving Market Dominant Price...

77 FR 55813 - Transition of DOE-ID Public Reading Room

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... to the INL Research Library at 1776 Science Center Drive, Idaho Falls, ID 83401, beginning September... Library, 1776 Science Center Drive, Idaho Falls, ID 83401. FOR FURTHER INFORMATION CONTACT: Clayton...

A Contextual Model for Identity Management (IdM) Interfaces

ERIC Educational Resources Information Center

Fuller, Nathaniel J.

2014-01-01

The usability of Identity Management (IdM) systems is highly dependent upon design that simplifies the processes of identification, authentication, and authorization. Recent findings reveal two critical problems that degrade IdM usability: (1) unfeasible techniques for managing various digital identifiers, and (2) ambiguous security interfaces.…

How to save distressed IDS-physician marriages: a case study.

PubMed

Collins, H; Johnson, B A

1998-04-01

A hospital-driven IDS that encounters serious problems resulting from ownership of a physician practice should address those problems by focusing on three core areas: vision and leadership, effectiveness of operations, and physician compensation arrangements. If changes in these areas do not lead to improvements, the IDS may need to consider organizational restructuring. In one case study, a hospital-driven IDS faced the problem of owning a poorly performing MSO with a captive physician group. The IDS's governing board determined that the organization lacked effective communication with the physicians and that realization of the organization's vision would require greater physician involvement in organizational decision making. The organization is expected to undergo some corporate reorganization in which physicians will acquire an equity interest in the enterprise.

Picture This: How to Establish an Effective School ID Card Program

ERIC Educational Resources Information Center

Finkelstein, David

2013-01-01

Most school districts do not have an ID card policy that everyone knows and follows, yet. many school districts are implementing ID card programs to address concerns about safety, efficiency, and convenience. A well-thought-out ID card program leads to greater security and smoother operations throughout the school and should thus be a priority.…

75 FR 34787 - In the Matter of Luminant Generation Company LLC; Comanche Peak Steam Electric Station...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

[email protected] , or by telephone at (301) 415-1677, to request (1) a digital ID certificate, which allows the... its counsel or representative, already holds an NRC- issued digital ID certificate). Based upon this... Secretary has not already established an electronic docket. Information about applying for a digital ID...

A&M. Plot plan of administration and A&M areas. Shows relationships ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A&M. Plot plan of administration and A&M areas. Shows relationships among administration buildings and to A&M building (TAN-607), railroad turntable. Ralph M. Parsons 902-2&3-ANP-U 3. Date: December 1952. INEEL index code no. 032-0100-00-693-106690 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

20 CFR 501.8 - Clerk of the Office of the Appellate Boards; docket of proceedings; records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Clerk of the Office of the Appellate Boards; docket of proceedings; records. 501.8 Section 501.8 Employees' Benefits EMPLOYEES' COMPENSATION APPEALS BOARD, DEPARTMENT OF LABOR RULES OF PROCEDURE § 501.8 Clerk of the Office of the Appellate Boards; docket of proceedings; records. (a) Location...

78 FR 39279 - United States Department of Energy; Bonneville Power Administration; Notice of Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. NJ13-10-000] United States Department of Energy; Bonneville Power Administration; Notice of Petition for Declaratory Order Take notice... (OATT) and a Petition for Declaratory Order requesting the Commission find that Bonneville's OATT, as...

ISS/IDS Detector Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cervera-Villanueva, A.

2008-02-21

This article summarises the results obtained by the detector working group of the 'International Scooping Study' (ISS) of a future neutrino oscillations facility. Special emphasis is put on far detectors, for which some of the main issues are identified. A detector R and D strategy in the context of the 'International Design Study' (IDS) for a neutrino factory is also presented.

76 FR 65739 - Iowa; Amendment No. 3 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1998-DR; Docket ID FEMA-2011-0001] Iowa; Amendment No. 3 to Notice of a Major Disaster Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. [[Page 65740

Global Organics LLC d/b/a/ BioFlora; Proposed Settlement of Clean Water Act Class I Administrative Penalty

EPA Pesticide Factsheets

Public Notice of Proposed Settlement of Clean Water Act Class I Administrative Penalty Matter and Opportunity to Comment In the Matter of Global Organics, LLC d/b/a/ BioFlora, Docket Number CWA-09-2018-0008.

78 FR 13348 - Science Board to the Food and Drug Administration Advisory Committee; Amendment of Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001... for Devices and Radiological Health Research Review subcommittee and the Global Health subcommittee. Progress updates will be presented regarding the Global Health subcommittee and the recently established...

75 FR 13568 - MMS Information Collection Activity: 1010-0142, Decommissioning Activities, Extension of a...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-22

... report 2 on plans for re- entry to complete or permanently abandon the well and inspection report. 1722(h... entry titled ``Enter Keyword or ID,'' enter docket ID MMS-2010-OMM-0011 then click search. Follow the...

76 FR 43196 - Implementation of the Truth in Caller ID Act

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-20

...In this Report and Order (Order), the Commission adopts rules to implement the Truth in Caller ID Act of 2009 (Truth in Caller ID Act, or Act). The Truth in Caller ID Act, and the Commission's implementing rules, prohibit any person or entity from knowingly altering or manipulating caller identification information with the intent to defraud, cause harm, or wrongfully obtain anything of value.

77 FR 72917 - Editorial Corrections to the Commerce Control List of the Export Administration Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-07

... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Part 774 [Docket No. 120320200-2296-01] RIN 0694-AF62 Editorial Corrections to the Commerce Control List of the Export Administration Regulations AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: This final rule...

76 FR 70150 - Draft Guidance for Industry and Food and Drug Administration Staff; Investigational Device...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

... proof of principle and initial clinical safety data before the device design is finalized. This draft... to the Division of Dockets Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane, rm.... Early feasibility studies allow for early clinical evaluation of devices to provide proof of principle...

ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.

Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, wemore » examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.« less

Guinea Pig ID-Like Families of SINEs

PubMed Central

Kass, David H.; Schaetz, Brian A.; Beitler, Lindsey; Bonney, Kevin M.; Jamison, Nicole; Wiesner, Cathy

2009-01-01

Previous studies have indicated a paucity of SINEs within the genomes of the guinea pig and nutria, representatives of the Hystricognathi suborder of rodents. More recent work has shown that the guinea pig genome contains a large number of B1 elements, expanding to various levels among different rodents. In this work we utilized A–B PCR and screened GenBank with sequences from isolated clones to identify potentially uncharacterized SINEs within the guinea pig genome, and identified numerous sequences with a high degree of similarity (>92%) specific to the guinea pig. The presence of A-tails and flanking direct repeats associated with these sequences supported the identification of a full-length SINE, with a consensus sequence notably distinct from other rodent SINEs. Although most similar to the ID SINE, it clearly was not derived from the known ID master gene (BC1), hence we refer to this element as guinea pig ID-like (GPIDL). Using the consensus to screen the guinea pig genomic database (Assembly CavPor2) with Ensembl BlastView, we estimated at least 100,000 copies, which contrasts markedly to just over 100 copies of ID elements. Additionally we provided evidence of recent integrations of GPIDL as two of seven analyzed conserved GPIDL-containing loci demonstrated presence/absence variants in Cavia porcellus and C. aperea. Using intra-IDL PCR and sequence analyses we also provide evidence that GPIDL is derived from a hystricognath-specific SINE family. These results demonstrate that this SINE family continues to contribute to the dynamics of genomes of hystricognath rodents. PMID:19232383

Guinea pig ID-like families of SINEs.

PubMed

Kass, David H; Schaetz, Brian A; Beitler, Lindsey; Bonney, Kevin M; Jamison, Nicole; Wiesner, Cathy

2009-05-01

Previous studies have indicated a paucity of SINEs within the genomes of the guinea pig and nutria, representatives of the Hystricognathi suborder of rodents. More recent work has shown that the guinea pig genome contains a large number of B1 elements, expanding to various levels among different rodents. In this work we utilized A-B PCR and screened GenBank with sequences from isolated clones to identify potentially uncharacterized SINEs within the guinea pig genome, and identified numerous sequences with a high degree of similarity (>92%) specific to the guinea pig. The presence of A-tails and flanking direct repeats associated with these sequences supported the identification of a full-length SINE, with a consensus sequence notably distinct from other rodent SINEs. Although most similar to the ID SINE, it clearly was not derived from the known ID master gene (BC1), hence we refer to this element as guinea pig ID-like (GPIDL). Using the consensus to screen the guinea pig genomic database (Assembly CavPor2) with Ensembl BlastView, we estimated at least 100,000 copies, which contrasts markedly to just over 100 copies of ID elements. Additionally we provided evidence of recent integrations of GPIDL as two of seven analyzed conserved GPIDL-containing loci demonstrated presence/absence variants in Cavia porcellus and C. aperea. Using intra-IDL PCR and sequence analyses we also provide evidence that GPIDL is derived from a hystricognath-specific SINE family. These results demonstrate that this SINE family continues to contribute to the dynamics of genomes of hystricognath rodents.

Defining the safe current limit for opening ID photon shutter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seletskiy, S.

The NSLS-II storage ring is protected from possible damage from insertion devices (IDs) synchrotron radiation by a dedicated active interlock system (AIS). It monitors electron beam position and angle and triggers beam drop if beam orbit exceeds the boundaries of pre-calculated active interlock envelope (AIE). The beamlines (BL) and beamline frontends (FE) are designed under assumption that the electron beam is interlocked within the AIE. For historic reasons the AIS engages the ID active interlock (AI-ID) at any non-zero beam current whenever the ID photon shutter (IDPS) is getting opened. Such arrangement creates major inconveniences for BLs commissioning. Apparently theremore » is some IDPS safe current limit (SCL) under which the IDPS can be opened without interlocking the e-beam. The goal of this paper is to find such limit.« less

The Self-Identity Protein IdsD Is Communicated between Cells in Swarming Proteus mirabilis Colonies.

PubMed

Saak, Christina C; Gibbs, Karine A

2016-12-15

Proteus mirabilis is a social bacterium that is capable of self (kin) versus nonself recognition. Swarming colonies of this bacterium expand outward on surfaces to centimeter-scale distances due to the collective motility of individual cells. Colonies of genetically distinct populations remain separate, while those of identical populations merge. Ids proteins are essential for this recognition behavior. Two of these proteins, IdsD and IdsE, encode identity information for each strain. These two proteins bind in vitro in an allele-restrictive manner. IdsD-IdsE binding is correlated with the merging of populations, whereas a lack of binding is correlated with the separation of populations. Key questions remained about the in vivo interactions of IdsD and IdsE, specifically, whether IdsD and IdsE bind within single cells or whether IdsD-IdsE interactions occur across neighboring cells and, if so, which of the two proteins is exchanged. Here we demonstrate that IdsD must originate from another cell to communicate identity and that this nonresident IdsD interacts with IdsE resident in the recipient cell. Furthermore, we show that unbound IdsD in recipient cells does not cause cell death and instead appears to contribute to a restriction in the expansion radius of the swarming colony. We conclude that P. mirabilis communicates IdsD between neighboring cells for nonlethal kin recognition, which suggests that the Ids proteins constitute a type of cell-cell communication. We demonstrate that self (kin) versus nonself recognition in P. mirabilis entails the cell-cell communication of an identity-encoding protein that is exported from one cell and received by another. We further show that this intercellular exchange affects swarm colony expansion in a nonlethal manner, which adds social communication to the list of potential swarm-related regulatory factors. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

The Self-Identity Protein IdsD Is Communicated between Cells in Swarming Proteus mirabilis Colonies

PubMed Central

Saak, Christina C.

2016-01-01

ABSTRACT Proteus mirabilis is a social bacterium that is capable of self (kin) versus nonself recognition. Swarming colonies of this bacterium expand outward on surfaces to centimeter-scale distances due to the collective motility of individual cells. Colonies of genetically distinct populations remain separate, while those of identical populations merge. Ids proteins are essential for this recognition behavior. Two of these proteins, IdsD and IdsE, encode identity information for each strain. These two proteins bind in vitro in an allele-restrictive manner. IdsD-IdsE binding is correlated with the merging of populations, whereas a lack of binding is correlated with the separation of populations. Key questions remained about the in vivo interactions of IdsD and IdsE, specifically, whether IdsD and IdsE bind within single cells or whether IdsD-IdsE interactions occur across neighboring cells and, if so, which of the two proteins is exchanged. Here we demonstrate that IdsD must originate from another cell to communicate identity and that this nonresident IdsD interacts with IdsE resident in the recipient cell. Furthermore, we show that unbound IdsD in recipient cells does not cause cell death and instead appears to contribute to a restriction in the expansion radius of the swarming colony. We conclude that P. mirabilis communicates IdsD between neighboring cells for nonlethal kin recognition, which suggests that the Ids proteins constitute a type of cell-cell communication. IMPORTANCE We demonstrate that self (kin) versus nonself recognition in P. mirabilis entails the cell-cell communication of an identity-encoding protein that is exported from one cell and received by another. We further show that this intercellular exchange affects swarm colony expansion in a nonlethal manner, which adds social communication to the list of potential swarm-related regulatory factors. PMID:27672195

77 FR 41320 - Suspension of Community Eligibility

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 64 [Docket ID FEMA-2012-0003; Internal Agency Docket No. FEMA-8237] Suspension of Community Eligibility AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final rule. SUMMARY: This rule identifies communities where the...

76 FR 30375 - Mississippi; Amendment No. 3 to Notice of an Emergency Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-3320-EM; Docket ID FEMA-2011-0001] Mississippi; Amendment No. 3 to Notice of an Emergency Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: This notice amends the...

76 FR 3595 - Proposed Flood Elevation Determinations for Cumberland County, ME (All Jurisdictions)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 [Docket ID FEMA-2008-0020; Internal Agency Docket No. FEMA-B-1060] Proposed Flood Elevation Determinations for Cumberland County, ME (All Jurisdictions) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice of...

75 FR 7956 - Changes in Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 65 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-B-1073] Changes in Flood Elevation Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Interim rule. SUMMARY: This interim rule lists...

78 FR 21171 - International Mail Product

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... POSTAL REGULATORY COMMISSION [Docket No. CP2013-57; Order No. 1690] International Mail Product... have the Agreement included within the existing IBRS Competitive Contract 3 product on grounds of... Contract 3 product in Docket No. CP2012-18. Id. at 3. [[Page 21172

[Concurrent validity of the HAWIK-IV and the Intelligence and Development Scales (IDS)].

PubMed

Hagmann-von Arx, Priska; Grob, Alexander; Petermann, Franz; Daseking, Monika

2012-01-01

The present study examined the concurrent validity of the Hamburg Wechsler Intelligenztest für Kinder - IV (HAWIK-IV; Petermann & Petermann, 2010) and the Intelligence and Development Scales (IDS; Grob, Meyer & Hagmann-von Arx, 2009). HAWIK-IV and IDS were administered in counterbalanced order to N = 172 children aged 6 to 11 years. The study presents the descriptive statistics, correlations, and an exploratory factor analysis of the data. There is a high correlation between HAWIK-IV Full Scale IQ and IDS intelligence score (r = .83). HAWIK-IV indices showed moderate to high correlations with the cognitive scales of the IDS (Cognition, Language, Mathematics). Low to absent correlations were found between HAWIK-IV indices and the noncognitive scales of the IDS (Social-Emotional Competence, Psychomotor, Achievement Motivation). The factor structure can be interpreted meaningfully and allows integration of the IDS cognitive, language, and mathematical subtests into the four HAWIK-IV indices. The results show that HAWIK-IV and IDS test results can be related to each other.

78 FR 72570 - Import Administration; Change of Agency Name for Instruments and Apparatus for Educational and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

... [Docket No.: 131114957-3957-01] Import Administration; Change of Agency Name for Instruments and Apparatus... apparatus for educational and scientific institutions. 15 CFR Part 303 Watches, Watch movements and jewelry program. PART 301--INSTRUMENTS AND APPARATUS FOR EDUCATIONAL AND SCIENTIFIC INSTITUTIONS 0 1. The...

Regulation of Id2 expression in EL4 T lymphoma cells overexpressing growth hormone.

PubMed

Weigent, Douglas A

2009-01-01

In previous studies, we have shown that overexpression of growth hormone (GH) in cells of the immune system upregulates proteins involved in cell growth and protects from apoptosis. Here, we report that overexpression of GH in EL4 T lymphoma cells (GHo) also significantly increased levels of the inhibitor of differentiation-2 (Id2). The increase in Id2 was suggested in both Id2 promoter luciferase assays and by Western analysis for Id2 protein. To identify the regulatory elements that mediate transcriptional activation by GH in the Id2 promoter, promoter deletion analysis was performed. Deletion analysis revealed that transactivation involved a 301-132bp region upstream to the Id2 transcriptional start site. The pattern in the human GHo Jurkat T lymphoma cell line paralleled that found in the mouse GHo EL4 T lymphoma cell line. Significantly less Id2 was detected in the nucleus of GHo EL4 T lymphoma cells compared to vector alone controls. Although serum increased the levels of Id2 in control vector alone cells, no difference was found in the total levels of Id2 in GHo EL4 T lymphoma cells treated with or without serum. The increase in Id2 expression in GHo EL4 T lymphoma cells measured by Id2 promoter luciferase expression and Western blot analysis was blocked by the overexpression of a dominant-negative mutant of STAT5. The results suggest that in EL4 T lymphoma cells overexpressing GH, there is an upregulation of Id2 protein that appears to involve STAT protein activity.

Best practices for the implementation of the REAL ID Act.

DOT National Transportation Integrated Search

2015-10-01

The REAL ID Act specifies the minimum standards that must be used to produce and issue drivers license and : identification cards that are REAL ID compliant. Beginning in 2020, if a person does not possess a form of : identification that meets REA...

ID card number detection algorithm based on convolutional neural network

NASA Astrophysics Data System (ADS)

Zhu, Jian; Ma, Hanjie; Feng, Jie; Dai, Leiyan

2018-04-01

In this paper, a new detection algorithm based on Convolutional Neural Network is presented in order to realize the fast and convenient ID information extraction in multiple scenarios. The algorithm uses the mobile device equipped with Android operating system to locate and extract the ID number; Use the special color distribution of the ID card, select the appropriate channel component; Use the image threshold segmentation, noise processing and morphological processing to take the binary processing for image; At the same time, the image rotation and projection method are used for horizontal correction when image was tilting; Finally, the single character is extracted by the projection method, and recognized by using Convolutional Neural Network. Through test shows that, A single ID number image from the extraction to the identification time is about 80ms, the accuracy rate is about 99%, It can be applied to the actual production and living environment.

77 FR 16036 - Guidance for Industry, Third Parties and Food and Drug Administration Staff; Medical Device ISO...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-19

... comments to the Division of Dockets Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane... Organization for Standardization (ISO) 13485:2003 ``Medical devices--Quality management systems--Requirements... management systems--Requirements for regulatory purposes,'' (ISO 13485:2003) or a national adoption of this...