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Sample records for administration fra plans

  1. 49 CFR 219.602 - FRA Administrator's determination of random drug testing rate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false FRA Administrator's determination of random drug... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Random Alcohol and Drug Testing Programs § 219.602 FRA Administrator's determination of random...

  2. 49 CFR 219.608 - FRA Administrator's determination of random alcohol testing rate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Random Alcohol and Drug Testing Programs § 219.608 FRA Administrator's determination of random alcohol... random selection, with each pool containing the covered employees who are subject to testing at the...

  3. 24 CFR 982.54 - Administrative plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Administrative plan. 982.54 Section... SECTION 8 TENANT-BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM HUD Requirements and PHA Plan for Administration of Program § 982.54 Administrative plan. (a) The PHA must adopt a written administrative plan...

  4. 49 CFR 219.602 - FRA Administrator's determination of random drug testing rate.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE... of the selection process. (f) The railroad must randomly select a sufficient number of covered... objective, neutral criteria which ensures that every covered employee has a substantially equal...

  5. 49 CFR 219.602 - FRA Administrator's determination of random drug testing rate.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE... of the selection process. (f) The railroad must randomly select a sufficient number of covered... objective, neutral criteria which ensures that every covered employee has a substantially equal...

  6. Local Administrators Planning Handbook. Final Report.

    ERIC Educational Resources Information Center

    Dyrenfurth, Michael J.; Dunlap, William S.

    As part of a project to develop a planning guide to assist local vocational education administrators in improving their planning efforts, a needs assessment questionnaire was developed to identify the degree of need for assistance in planning activities. Two hundred sixty-four Missouri local vocational administrators completed the pilot-tested…

  7. 75 FR 57820 - National Credit Union Administration Restoration Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... ADMINISTRATION National Credit Union Administration Restoration Plan AGENCY: National Credit Union Administration (NCUA). ACTION: Approval of National Credit Union Administration restoration plan. On September 16, 2010, the National Credit Union Administration (NCUA) implemented a Restoration Plan for the National...

  8. Disaster Planning Guide for School Administrators.

    ERIC Educational Resources Information Center

    Kansas State Dept. of Education, Topeka.

    This guide for Kansas school administrators will provide a method by which positive safety and emergency planning can be effected. Safety and emergency planning are those efforts by school administrators, teachers, and other staff personnel to provide for a total environment of protection. State, county, and local governmental agencies should…

  9. 24 CFR 982.54 - Administrative plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Administrative plan. 982.54 Section 982.54 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 TENANT BASED...

  10. 24 CFR 982.54 - Administrative plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Administrative plan. 982.54 Section 982.54 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 TENANT BASED...

  11. 47 CFR 52.13 - North American Numbering Plan Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false North American Numbering Plan Administrator. 52... SERVICES (CONTINUED) NUMBERING Administration § 52.13 North American Numbering Plan Administrator. (a) The North American Numbering Plan Administrator (NANPA) shall be an independent and impartial...

  12. 47 CFR 52.13 - North American Numbering Plan Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false North American Numbering Plan Administrator. 52... SERVICES (CONTINUED) NUMBERING Administration § 52.13 North American Numbering Plan Administrator. (a) The North American Numbering Plan Administrator (NANPA) shall be an independent and impartial...

  13. 47 CFR 52.13 - North American Numbering Plan Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false North American Numbering Plan Administrator. 52... SERVICES (CONTINUED) NUMBERING Administration § 52.13 North American Numbering Plan Administrator. (a) The North American Numbering Plan Administrator (NANPA) shall be an independent and impartial...

  14. 7 CFR 225.4 - Program management and administration plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Program management and administration plan. 225.4... Provisions § 225.4 Program management and administration plan. (a) Not later than February 15 of each year, each State agency shall submit to FNSRO a Program management and administration plan for that...

  15. 9. PHOTOCOPY, FOUNDATION AND FLOORING PLANS FOR ADMINISTRATION BUILDING. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. PHOTOCOPY, FOUNDATION AND FLOORING PLANS FOR ADMINISTRATION BUILDING. - NIKE Missile Base SL-40, Administration Building, East central portion of base, southeast of Mess Hall, northeast of HIPAR Equipment Building, Hecker, Monroe County, IL

  16. Planning, Programing, and Administration of Functional Literacy.

    ERIC Educational Resources Information Center

    Bhola, H. S.

    The document was prepared as part of a UNESCO contract to train 16 counterpart officials of UNESCO-sponsored literacy projects. Functional literacy was studied in three parts, all dealing with the total planning process. First was project planning. Literacy projects must consider national educational plans and be related to relevant economic…

  17. Overview of Strategic Planning. Administrative Report.

    ERIC Educational Resources Information Center

    Raze, Nasus

    Strategic planning is a process by which the guiding members of an organization envision its future and develop tactics to achieve that future. This paper discusses the nature and purposes of strategic planning in educational organizations, and presents a 10-step generic model to illustrate the basic components of strategic planning. These 10…

  18. 49 CFR 228.407 - Analysis of work schedules; submissions; FRA review and approval of submissions; fatigue...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Analysis of work schedules; submissions; FRA review and approval of submissions; fatigue mitigation plans. 228.407 Section 228.407 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HOURS OF SERVICE OF...

  19. Highway Safety Program Manual: Volume O: Planning and Administration.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    As the introductory volume to the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices), the document concentrates on aspects of planning and administration of a statewide highway safety program. Topics discussed are: the purpose of planning and administration,…

  20. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Administration of affirmative action plan. 906.5 Section 906.5 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer...

  1. 7 CFR 225.4 - Program management and administration plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM State Agency Provisions § 225.4 Program management and administration plan. (a) Not later than February 15 of each year... 7 Agriculture 4 2014-01-01 2014-01-01 false Program management and administration plan....

  2. 7 CFR 225.4 - Program management and administration plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM State Agency Provisions § 225.4 Program management and administration plan. (a) Not later than February 15 of each year... 7 Agriculture 4 2012-01-01 2012-01-01 false Program management and administration plan....

  3. 7 CFR 225.4 - Program management and administration plan.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM State Agency Provisions § 225.4 Program management and administration plan. (a) Not later than February 15 of each year... 7 Agriculture 4 2011-01-01 2011-01-01 false Program management and administration plan....

  4. 7 CFR 225.4 - Program management and administration plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM State Agency Provisions § 225.4 Program management and administration plan. (a) Not later than February 15 of each year... 7 Agriculture 4 2013-01-01 2013-01-01 false Program management and administration plan....

  5. Planning for Technology: A Guidebook for School Administrators.

    ERIC Educational Resources Information Center

    Lumley, Richard D.; Bailey, Gerald D.

    This guidebook was designed to help school administrators with little or no experience in technology planning initiate and carry out a step-by-step planning cycle. It shows how to organize a district for instructional technology integration by following a six-step planning model. Six chapters, based on the steps of the model, begin with a set of…

  6. 51. Roof plans, General Services Administration, Construction Management Division, Region ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Roof plans, General Services Administration, Construction Management Division, Region 2, New York, October 29, 1976. Scale 1/31=1. - U.S. Navy Fleet Supply Base, Storehouse No. 1, 830 Third Avenue, Brooklyn, Kings County, NY

  7. Alvin Community College Administrative and Professional Staff Development Plan.

    ERIC Educational Resources Information Center

    Lewis, Troy

    The document presents a point-based administrative/professional staff development plan developed by Alvin Community College (Texas). A list of activities and their respective point values are utilized by administrators to document professional growth and development, with a thirty-point minimum per year necessary for advancement to the next…

  8. Succession Planning: A Necessary Strategy for Rural School Administration.

    ERIC Educational Resources Information Center

    Wallin, Dawn C.

    2001-01-01

    Succession planning focuses on anticipated future administrative positions, the expected skill requirements of those positions, and developing potential candidates to fill the positions. Although succession planning is basically a business oriented model, it seems appropriate for rural educational settings. Strategies for implementing succession…

  9. Plan selection in Medicare Part D: Evidence from administrative data

    PubMed Central

    Heiss, Florian; Leive, Adam; McFadden, Daniel; Winter, Joachim

    2014-01-01

    We study the Medicare Part D prescription drug insurance program as a bellwether for designs of private, non-mandatory health insurance markets, focusing on the ability of consumers to evaluate and optimize their choices of plans. Our analysis of administrative data on medical claims in Medicare Part D suggests that fewer than 25 percent of individuals enroll in plans that are ex ante as good as the least cost plan specified by the Plan Finder tool made available to seniors by the Medicare administration, and that consumers on average have expected excess spending of about $300 per year, or about 15 percent of expected total out-of-pocket cost for drugs and Part D insurance. These numbers are hard to reconcile with decision costs alone; it appears that unless a sizeable fraction of consumers place large values on plan features other than cost, they are not optimizing effectively. PMID:24308882

  10. 77 FR 48591 - State Rail Plan Guidance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... grants authorized in the Act and available under the High-Speed Intercity Passenger Rail program. This... Federal Railroad Administration State Rail Plan Guidance AGENCY: Federal Railroad Administration (FRA), Department of Transportation (DOT). ACTION: Request for Public Comment on Proposed State Rail Plan...

  11. Security administration plan for HANDI 2000 business management system

    SciTech Connect

    Wilson, D.

    1998-09-29

    This document encompasses and standardizes the integrated approach for security within the PP and Ps applications, It also identifies the security tools and methods to be used. The Security Administration Plan becomes effective as of this document`s acceptance and will provide guidance through implementation efforts and, as a ``living document`` will support the operations and maintenance of the system.

  12. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility....

  13. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility....

  14. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility....

  15. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility....

  16. The Administrative Role in Hospice Planning and Organization.

    ERIC Educational Resources Information Center

    Sallady, Susan A.

    1982-01-01

    Addresses the specific advantages to new hospices of incorporating administrative resource people in the planning and organization phases of their programs. Describes organizational structure and the role of the interdisciplinary team. An annotated bibliography summarizes hospice adminstrative resources and research. (Author/JAC)

  17. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Administrative and planning costs. 1006.230 Section 1006.230 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE HAWAIIAN HOUSING BLOCK GRANT PROGRAM Eligible Activities §...

  18. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Administrative and planning costs. 1006.230 Section 1006.230 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE HAWAIIAN HOUSING BLOCK GRANT PROGRAM Eligible Activities §...

  19. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Administrative and planning costs. 1006.230 Section 1006.230 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE HAWAIIAN HOUSING BLOCK GRANT PROGRAM Eligible Activities §...

  20. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Administrative and planning costs. 1006.230 Section 1006.230 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE HAWAIIAN HOUSING BLOCK GRANT PROGRAM Eligible Activities §...

  1. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Administrative and planning costs. 1006.230 Section 1006.230 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE HAWAIIAN HOUSING BLOCK GRANT PROGRAM Eligible Activities §...

  2. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Eligible administrative and planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development HOME INVESTMENT PARTNERSHIPS PROGRAM Program Requirements Eligible and Prohibited Activities § 92.207...

  3. Federal Aviation Administration aging aircraft nondestructive inspection research plan

    NASA Technical Reports Server (NTRS)

    Seher, Chris C.

    1992-01-01

    This paper highlights the accomplishments and plans of the Federal Aviation Administration (FAA) for the development of improved nondestructive evaluation (NDE) equipment, procedures, and training. The role of NDE in aircraft safety and the need for improvement are discussed. The FAA program participants, and coordination of activities within the program and with relevant organizations outside the program are also described.

  4. Planning for the Administrative Microcomputer Local Area Network.

    ERIC Educational Resources Information Center

    Rohr, Theodore; Devoti, Bart

    An overview is provided of the methods used by the Forest Park campus of St. Louis Community College (SLCC) to plan and develop a local area network (LAN) for administrative microcomputers. The first three sections provide brief descriptions of the SLCC District, SLCC, and the Forest Park campus. Section IV looks at the organization of…

  5. The Legal Aspects of Educational Planning and Administration. Fundamentals of Educational Planning.

    ERIC Educational Resources Information Center

    Durand-Prinborgne, Claude

    The purpose of this monograph, which is aimed at educational planners, is to explain the essential aspects of the relationship between planning and law. It is intended to illustrate the role of law in the planning and administration of school systems and thus familiarize education specialists with the tools needed to understand legal…

  6. 47 CFR 52.12 - North American Numbering Plan Administrator and B&C Agent.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false North American Numbering Plan Administrator and...) COMMON CARRIER SERVICES (CONTINUED) NUMBERING Administration § 52.12 North American Numbering Plan Administrator and B&C Agent. The North American Numbering Plan Administrator (“NANPA”) and the associated...

  7. 26 CFR 1.414(g)-1 - Definition of plan administrator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 5 2011-04-01 2011-04-01 false Definition of plan administrator. 1.414(g)-1...(g)-1 Definition of plan administrator. (a) In general. For purposes of part I of subchapter D of... for a plan year specifically designates a person or a group of persons as plan administrator,...

  8. 26 CFR 1.414(g)-1 - Definition of plan administrator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 5 2013-04-01 2013-04-01 false Definition of plan administrator. 1.414(g)-1...(g)-1 Definition of plan administrator. (a) In general. For purposes of part I of subchapter D of... for a plan year specifically designates a person or a group of persons as plan administrator,...

  9. 26 CFR 1.414(g)-1 - Definition of plan administrator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 5 2012-04-01 2011-04-01 true Definition of plan administrator. 1.414(g)-1...(g)-1 Definition of plan administrator. (a) In general. For purposes of part I of subchapter D of... for a plan year specifically designates a person or a group of persons as plan administrator,...

  10. State administration and financing of family planning services.

    PubMed

    Weinberg, D

    1972-04-01

    A 1971 survey by the Center for Family Planning Program Development consisted of a questionnaire mailed to health and welfare directors in 50 states and 5 federal jurisdictions concerning their family planning policies and administrative practices. 52 agencies responded; Guam, Mississippi, and Louisiana did not. The major funding for state health agencies was allocated by HEW and by maternal and child health (MCH) formula grants under Title 5 of the Social Security Act. 11 states made additional expenditures of $1.7 million for a variety of purposes. 21 states required local welfare departments to purchase services under the Medicaid program established by Title 19 of the Social Security Act. Administration was assigned to specific organizations within the state health agencies. 31 states reported a total of 128 full-time professional personnel, with 90 assigned at state headquarters level. In general, on a state-by-state basis, the full-time staff does not correspond to the size of the appropriations. Survey findings were useful measures of resource commitments to family planning services by state health and welfare agencies and provided data on future levels of resource requirements. PMID:5052570

  11. 26 CFR 1.414(g)-1 - Definition of plan administrator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Definition of plan administrator. 1.414(g)-1... Definition of plan administrator. (a) In general. For purposes of part I of subchapter D of chapter 1 of the... specifically designates a person or a group of persons as plan administrator, the person or group of...

  12. Contracting with Medicare Advantage plans: a brief for critical access hospital administrators.

    PubMed

    Mason, Michelle; Fraser-Maginn, Roslyn; Mueller, Keith; King, Jennifer; Radford, Andrea; Slifkin, Rebecca; Lenardson, Jennifer; Silver, Lauren; Mueller, Curt

    2005-12-01

    This document summarizes the experience of CAH administrators with contracts offered by Medicare Advantage (MA) plans. Telephone surveys were conducted with CAH administrators across the country to learn about their experiences with MA plans. This brief includes information about the contract terms administrators have been offered, their experiences negotiating with MA plans, and their advice for others dealing with this issue. PMID:16397967

  13. NEPA meets government reinvention: Bonneville Power Administration`s business plan E.I.S.

    SciTech Connect

    Wolfe, D.V.; Alton, C.; Linehan, A.O.

    1995-12-01

    During the early 1990`s Bonneville Power Administration (BPA) found its role as the Pacific Northwest`s largest wholesale marketer of electric power challenged by energy market deregulation, increasing competition from utilities and non-utility power sources, and uncertainty about future costs. Moreover, the rapid decline of endangered salmon stocks appeared to be leading to significant changes in the operations of the Columbia River hydroelectric system and limitations in the amount of hydro power BPA could sell its utility customers. In response, BPA began a fundamental review of all of its power and transmission products, rates, organization, and administrative procedures. BPA`s reinvention was clearly a major Federal action subject to NEPA, and the Business Plan EIS quickly became the focus of both BPA`s effort to question the fundamental mechanisms of its operations, and of the many customers, environmental organizations, and interest groups that watchdog BPA`s activities. In developing the Business Plan EIS, BPA faced multiple challenges: (1) complex, interrelated issues, including power sales contract terms, power rates, hydroelectric operations and salmon survival, transmission system deregulation, energy resource choices, conservation program reinvention, and fish and wildlife program management reform; (2) drawing appropriate boundaries around the subject of analysis instead of letting the EIS become the {open_quotes}black hole{close_quotes} for every regional environmental issue; (3) framing and evaluating broad policy choices in an understandable and useful manner without getting lost in the detail of the myriad decisions BPA faces; (4) keeping pace with evolving management thinking about BPA`s new direction; (5) linking Business Plan choices to market responses and ultimately to environmental impacts. The Business Plan EIS is an innovative effort to address broad policy directions, marketing relationships, and environmental impacts.

  14. 49 CFR Appendix C to Part 209 - FRA's Policy Statement Concerning Small Entities

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false FRA's Policy Statement Concerning Small Entities C Appendix C to Part 209 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Pt. 209, App. C Appendix C to Part 209—FRA's...

  15. 49 CFR Appendix C to Part 215 - FRA Freight Car Standards Defect Code

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false FRA Freight Car Standards Defect Code C Appendix C to Part 215 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS Pt. 215, App. C Appendix C to Part 215—FRA Freight Car...

  16. 21 CFR 118.9 - Administration of the Salmonella Enteritidis (SE) prevention plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Administration of the Salmonella Enteritidis (SE) prevention plan. 118.9 Section 118.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... EGGS § 118.9 Administration of the Salmonella Enteritidis (SE) prevention plan. You must have one...

  17. 21 CFR 118.9 - Administration of the Salmonella Enteritidis (SE) prevention plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Administration of the Salmonella Enteritidis (SE) prevention plan. 118.9 Section 118.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... EGGS § 118.9 Administration of the Salmonella Enteritidis (SE) prevention plan. You must have one...

  18. 21 CFR 118.9 - Administration of the Salmonella Enteritidis (SE) prevention plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Administration of the Salmonella Enteritidis (SE) prevention plan. 118.9 Section 118.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... EGGS § 118.9 Administration of the Salmonella Enteritidis (SE) prevention plan. You must have one...

  19. 21 CFR 118.9 - Administration of the Salmonella Enteritidis (SE) prevention plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Administration of the Salmonella Enteritidis (SE) prevention plan. 118.9 Section 118.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... EGGS § 118.9 Administration of the Salmonella Enteritidis (SE) prevention plan. You must have one...

  20. 21 CFR 118.9 - Administration of the Salmonella Enteritidis (SE) prevention plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Administration of the Salmonella Enteritidis (SE) prevention plan. 118.9 Section 118.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... EGGS § 118.9 Administration of the Salmonella Enteritidis (SE) prevention plan. You must have one...

  1. 49 CFR Appendix C to Part 230 - FRA Inspection Forms

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false FRA Inspection Forms C Appendix C to Part 230 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Pt. 230, App. C Appendix...

  2. 49 CFR Appendix C to Part 230 - FRA Inspection Forms

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false FRA Inspection Forms C Appendix C to Part 230 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Pt. 230, App. C Appendix...

  3. 49 CFR Appendix C to Part 230 - FRA Inspection Forms

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false FRA Inspection Forms C Appendix C to Part 230 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Pt. 230, App. C Appendix...

  4. 29 CFR 2590.606-4 - Notice requirements for plan administrators.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Notice requirements for plan administrators. 2590.606-4 Section 2590.606-4 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR GROUP HEALTH PLANS RULES AND REGULATIONS FOR GROUP HEALTH PLANS Continuation Coverage, Qualified Medical Child...

  5. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 27....1178 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau, under delegated... clearinghouse(s) will administer the cost-sharing plan by, inter alia, determining the cost-sharing...

  6. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 24.241... Mhz Band § 24.241 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau.... This clearinghouse will administer the cost-sharing plan by, inter alia, maintaining all of the...

  7. 47 CFR 27.1162 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 27... § 27.1162 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau, under...(s). This clearinghouse(s) will administer the cost-sharing plan by, inter alia, determining the...

  8. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Headquarters is: 300 West Adams Street, Rm 310, Chicago, Illinois 60606. The fax number is 312-886-9634. The E...-3804. The E-mail address of the Regional Administrator for Region 5 is: John.Megary@fra.dot.gov....

  9. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Headquarters is: 300 West Adams Street, Rm 310, Chicago, Illinois 60606. The fax number is 312-886-9634. The E...-3804. The E-mail address of the Regional Administrator for Region 5 is: John.Megary@fra.dot.gov....

  10. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Headquarters is: 300 West Adams Street, Rm 310, Chicago, Illinois 60606. The fax number is 312-886-9634. The E...-3804. The E-mail address of the Regional Administrator for Region 5 is: John.Megary@fra.dot.gov....

  11. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Headquarters is: 300 West Adams Street, Rm 310, Chicago, Illinois 60606. The fax number is 312-886-9634. The E...-3804. The E-mail address of the Regional Administrator for Region 5 is: John.Megary@fra.dot.gov....

  12. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Headquarters is: 300 West Adams Street, Rm 310, Chicago, Illinois 60606. The fax number is 312-886-9634. The E...-3804. The E-mail address of the Regional Administrator for Region 5 is: John.Megary@fra.dot.gov....

  13. 76 FR 41859 - Waiver Petition Docket Numbers FRA-2011-0002, CSX Transportation Railroad, and FRA-2004-17565...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Register (75 FR 224) announcing the Union Pacific Railroad's request for an amendment to their existing... Administration (FRA) published a notice in the Federal Register (76 FR 10087) announcing the CSX Transportation... submitted on behalf of an association, business, labor union, etc.). You may review DOT's complete...

  14. The Study of School Facility Planning--Unimportant to Educational Administration Programs?

    ERIC Educational Resources Information Center

    Glass, Thomas E.

    1991-01-01

    Contends that preparation programs in educational administration usually do not directly cover facility planning or construction, or the assessment and maintenance of existing facilities. Suggests areas to be addressed in an educational facilities planning course. (12 references) (MLF)

  15. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of... CFR part 91. (e) Indirect Costs. Indirect costs may be charged to the HOME program under a cost... consolidated plan. Preparation of the consolidated plan required under 24 CFR part 91. Preparation includes...

  16. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of... CFR part 91. (e) Indirect Costs. Indirect costs may be charged to the HOME program under a cost... consolidated plan. Preparation of the consolidated plan required under 24 CFR part 91. Preparation includes...

  17. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of... CFR part 91. (e) Indirect Costs. Indirect costs may be charged to the HOME program under a cost... consolidated plan. Preparation of the consolidated plan required under 24 CFR part 91. Preparation includes...

  18. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of... CFR part 91. (e) Indirect Costs. Indirect costs may be charged to the HOME program under a cost... consolidated plan. Preparation of the consolidated plan required under 24 CFR part 91. Preparation includes...

  19. 40 CFR 77.4 - Administrator's action on proposed offset plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on proposed offset plans. 77.4 Section 77.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) EXCESS EMISSIONS § 77.4 Administrator's action on proposed offset plans....

  20. 26 CFR 1.414(g)-1 - Definition of plan administrator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 5 2014-04-01 2014-04-01 false Definition of plan administrator. 1.414(g)-1 Section 1.414(g)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED...(g)-1 Definition of plan administrator. (a) In general. For purposes of part I of subchapter D...

  1. 23 CFR Appendix F to Part 1200 - Planning and Administration (P&A) Costs

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Planning and Administration (P&A) Costs F Appendix F to... HIGHWAY SAFETY GRANT PROGRAMS Pt. 1200, App. F Appendix F to Part 1200—Planning and Administration (P&A) Costs (a) Policy. Federal participation in P&A activities shall not exceed 50 percent of the total...

  2. 23 CFR Appendix F to Part 1200 - PLANNING AND ADMINISTRATION (P&A) COSTS

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false PLANNING AND ADMINISTRATION (P&A) COSTS F APPENDIX F TO... HIGHWAY SAFETY GRANT PROGRAMS Pt. 1200, App. F APPENDIX F TO PART 1200—PLANNING AND ADMINISTRATION (P&A) COSTS (a) Policy. Federal participation in P&A activities shall not exceed 50 percent of the total...

  3. 20 CFR 632.39 - Administrative cost plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... a Native American grantee may be accounted for separately and be allocated by title and program....39 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Administrative Standards and Procedures § 632.39...

  4. 20 CFR 632.39 - Administrative cost plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a Native American grantee may be accounted for separately and be allocated by title and program....39 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Administrative Standards and Procedures § 632.39...

  5. School Business Administration: A Planning Approach. Third Edition.

    ERIC Educational Resources Information Center

    Candoli, I. Carl; And Others

    The school business administration function in the operation of American schools has undergone dramatic changes during the past several years. Changing demographics, high technology, the movement to professionalize school administration, and changes by the legislative and judicial systems have all had significant impact on the character of school…

  6. School Business Administration: A Planning Approach. Second Edition.

    ERIC Educational Resources Information Center

    Candoli, I. Carl; And Others

    Intended for both the student and the practitioner, this text examines the role and function of the school business administrator and offers practical information relevant to the job. The authors recognize that the function of school business administration has radically changed in response to social changes. They believe that conventional…

  7. Accounting and Financial Planning--Top Priorities for School Business Administrators.

    ERIC Educational Resources Information Center

    Walters, Donald L.

    Success for the business administrator depends largely on ability to identify priorities and to direct time, energy, and know-how accordingly. This study attempted to find out the priorities of the tasks of accounting and financial planning for school business administrators and the precise nature of the school business administrator's…

  8. 45 CFR 235.50 - State plan requirements for methods of personnel administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false State plan requirements for methods of personnel administration. 235.50 Section 235.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATION...

  9. 45 CFR 235.50 - State plan requirements for methods of personnel administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false State plan requirements for methods of personnel administration. 235.50 Section 235.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATION...

  10. Planned Giving Administration: The Business Officer's Guide [with DVD

    ERIC Educational Resources Information Center

    Brostrom, Forrest C.

    2005-01-01

    Some people associate planned giving with fancy trusts and exotic tax plans. The truth is far simpler and more profound. This book provides a comprehensive review of the subject, from the relative simplicity of outright gifts and bequests to the more complex workings of pooled income funds and retained life estates. The author lends a common sense…

  11. 36 CFR 219.13 - Plan amendment and administrative changes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... to new information or changing conditions. The responsible official has the discretion to determine... more plan components apply to all or part of the plan area (including management areas or geographic... be based on a new assessment; a monitoring report; or other documentation of new information,...

  12. 36 CFR 219.13 - Plan amendment and administrative changes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... to new information or changing conditions. The responsible official has the discretion to determine... more plan components apply to all or part of the plan area (including management areas or geographic... be based on a new assessment; a monitoring report; or other documentation of new information,...

  13. 36 CFR 219.13 - Plan amendment and administrative changes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to new information or changing conditions. The responsible official has the discretion to determine... more plan components apply to all or part of the plan area (including management areas or geographic... be based on a new assessment; a monitoring report; or other documentation of new information,...

  14. National Aeronautics and Space Administration plans for space communication technology

    NASA Technical Reports Server (NTRS)

    Alexovich, R. E.

    1979-01-01

    A program plan is presented for a space communications application utilizing the 30/20 GHz frequency bands (30 GHz uplink and 20 GHz downlink). Results of market demand studies and spacecraft systems studies which significantly affect the supporting research and technology program are also presented, along with the scheduled activities of the program plan.

  15. A Report on Administrative Compensation Planning for St. Paul Public School Personnel.

    ERIC Educational Resources Information Center

    Hooker, Clifford P.; Mueller, Van D.

    This report describes and analyzes various devices and techniques that may be utilized in planning local school administrative compensation. The document outlines broad overall goals for compensation planning, describes and evaluates the application of a compensation plan in the St. Paul schools, and proposes alternative strategies for…

  16. 78 FR 38846 - Potato Research and Promotion Plan; Amend the Administrative Committee Structure and Delete the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ...; ] DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 1207 Potato Research and Promotion Plan... of the Administrative Committee (Committee) of the U.S. Potato Board (Board) and deleting the Board's mailing address from the Potato Research and Promotion Plan. The Plan is administered by the Board...

  17. 29 CFR 4041.51 - Disclosure of information by plan administrator in distress termination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Disclosure of information by plan administrator in distress termination. 4041.51 Section 4041.51 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION PLAN TERMINATIONS TERMINATION OF SINGLE-EMPLOYER PLANS Distress Termination Process §...

  18. 29 CFR 4041.51 - Disclosure of information by plan administrator in distress termination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Disclosure of information by plan administrator in distress termination. 4041.51 Section 4041.51 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION PLAN TERMINATIONS TERMINATION OF SINGLE-EMPLOYER PLANS Distress Termination Process §...

  19. Elevated Fra-1 expression causes severe lipodystrophy.

    PubMed

    Luther, Julia; Driessler, Frank; Megges, Matthias; Hess, Andreas; Herbort, Bettina; Mandic, Vice; Zaiss, Mario M; Reichardt, Anne; Zech, Christine; Tuckermann, Jan P; Calkhoven, Cornelis F; Wagner, Erwin F; Schett, Georg; David, Jean-Pierre

    2011-05-01

    A shift from osteoblastogenesis to adipogenesis is one of the underlying mechanisms of decreased bone mass and increased fat during aging. We now uncover a new role for the transcription factor Fra-1 in suppressing adipogenesis. Indeed, Fra1 (Fosl1) transgenic (Fra1tg) mice, which developed progressive osteosclerosis as a result of accelerated osteoblast differentiation, also developed a severe general lipodystrophy. The residual fat of these mice appeared immature and expressed lower levels of adipogenic markers, including the fatty acid transporter Cd36 and the CCAAT/enhancer binding protein Cebpa. Consequently accumulation of triglycerides and free fatty acids were detected in the serum of fasting Fra1tg mice. Fra-1 acts cell autonomously because the adipogenic differentiation of Fra1 transgenic primary osteoblasts was drastically reduced, and overexpression of Fra-1 in an adipogenic cell line blocked their differentiation into adipocytes. Strikingly, Cebpa was downregulated in the Fra-1-overexpressing cells and Fra-1 could bind to the Cebpa promoter and directly suppress its activity. Thus, our data add to the known common systemic control of fat and bone mass, a new cell-autonomous level of control of cell fate decision by which the osteogenic transcription factor Fra-1 opposes adipocyte differentiation by inhibiting C/EBPα. PMID:21486951

  20. Impact of the 1985 Space World Administrative Radio Conference on frequency/orbit planning and use

    NASA Technical Reports Server (NTRS)

    Miller, E. F.

    1986-01-01

    The 1985 World Administrative Radio Conference (WARC-ORB-85) was held to determine which space radio services should be planned and which planning methods should be used. The second session of this Conference (WARC-ORB-88) will meet to develop the required plans. This paper presents the results of WARC-ORB-85, assesses the impact of those decisions, and identifies the intersessional work to be conducted by administrations and the CCIR (Consultative Committee on International Radio). The major decisions of WARC-ORB-85 were: (1) the restriction of additional planning to the fixed satellite service at identified frequencies; and (2) the selection of a planning method consisting of two parts (a) an allotment plan, and (b) improved procedures. The paper also discusses WARC-ORB-85 decisions relative to the Region 2 broadcast satellite service plans at 12 GHz, feederlink planning for Regions 1 and 3 broadcast satellites at 12 GHz, and sound broadcast satellite service.

  1. Impact of the 1985 space World Administrative Radio Conference on frequency/orbit planning and use

    NASA Technical Reports Server (NTRS)

    Miller, E. F.

    1986-01-01

    The 1985 World Administrative Radio Conference (WARC-ORB-85) was held to determine which space radio services should be planned and which planning methods should be used. The second session of this Conference (WARC-ORB-88) will meet to develop the required plans. This paper presents the results of WARC-ORB-85, assesses the impact of those decisions, and identifies the intersessional work to be conducted by administrations and the CCIR (consultative Committee on International Radio). The major decisions of WARC-ORB-85 were: (1) the restriction of additional planning to the fixed satellite service at identified frequencies; and (2) the selection of a planning method consisting of two parts: (a) an allotment plan, and (b) improved procedures. The paper also discusses WARC-ORB-85 decisions relative to the Region 2 broadcast satellite service plans at 12 GHz, feederlink planning for Regions 1 and 3 broadcast satellites at 12 GHz, and sound broadcast satellite service.

  2. Planning the future of JPL's management and administrative support systems around an integrated database

    NASA Technical Reports Server (NTRS)

    Ebersole, M. M.

    1983-01-01

    JPL's management and administrative support systems have been developed piece meal and without consistency in design approach over the past twenty years. These systems are now proving to be inadequate to support effective management of tasks and administration of the Laboratory. New approaches are needed. Modern database management technology has the potential for providing the foundation for more effective administrative tools for JPL managers and administrators. Plans for upgrading JPL's management and administrative systems over a six year period evolving around the development of an integrated management and administrative data base are discussed.

  3. 49 CFR 228.407 - Analysis of work schedules; submissions; FRA review and approval of submissions; fatigue...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Analysis of work schedules; submissions; FRA... Employees Engaged in Commuter or Intercity Rail Passenger Transportation § 228.407 Analysis of work schedules; submissions; FRA review and approval of submissions; fatigue mitigation plans. (a) Analysis...

  4. 44 CFR 206.437 - State administrative plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... requirements of 44 CFR parts 13 and 206; (xii) Provide quarterly progress reports to the Regional Administrator... costs provided under 44 CFR part 207 that the grantee will make available to subgrantees, and the basis... eligibility and key deadlines; (iii) Determine applicant eligibility; (iv) Conduct environmental...

  5. Peer Pressure to Drink: Implications for University Administration and Planning.

    ERIC Educational Resources Information Center

    Shore, Elsie R.; Rivers, P. Clayton

    1985-01-01

    Surveyed college students (N=688) from two universities to examine variables related to drinking, i.e., peer pressure, social ease, and desire to refrain from drinking. Results show class standing and gender to be variables affecting resistance to pressure to drink (RPD). Presents preventive strategies for university administrators. (BH)

  6. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the 1850-1990 Mhz Band § 24.241 Administration of the Cost-Sharing Plan. The Wireless Telecommunications...

  7. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the 1850-1990 Mhz Band § 24.241 Administration of the Cost-Sharing Plan. The Wireless Telecommunications...

  8. National Aeronautics and Space Administration. 2003 Strategic Plan

    NASA Technical Reports Server (NTRS)

    2003-01-01

    As the 21st century begins to unfold, NASA will focus, with renewed vigor, on the challenges and opportunities before us and on developing the unique capabilities that strengthen America and address our national needs. Our Mission is driven by science, exploration, and discovery, and it will be carried out with a firm commitment to fiscal responsibility. We will study climate change and the natural and human-induced hazards to Earth's ecosystem. We will help to counter the threat of international terrorism by developing technologies that can improve the security and safety of our air transportation system. We will lead the world into a new understanding of our planet, our solar system, and the universe around us, and in so doing, we will begin to understand whether life may have developed elsewhere in the cosmos. This strategic plan lays out our hopes for the future and the important things we seek to accomplish for America. We are privileged to be entrusted with these pursuits and thrilled to be able to carry them out. We invite you to join us on this great adventure. Releasing this strategic plan with our 2004 budget request represents our new commitment to the integration of budget and performance reporting. In this way, we will ensure that strategic priorities are aligned with and influence budget priorities. Our new Integrated Budget and Performance Document, a companion volume to this strategic plan, expands on the goals and objectives presented here and identifies the specific long-term and annual performance measures for which we will be held accountable.

  9. A plan for administrative computing at ANL FY1991 through FY1993

    SciTech Connect

    Caruthers, L.E.; O'Brien, D.E.; Bretscher, M.E.; Hischier, R.C.; Moore, N.J.; Slade, R.G.

    1990-10-01

    In July of 1988, Argonne National Laboratory management approved the restructuring of Computing Services into the Computing and Telecommunications Division, part of the Physical Research area of the Laboratory. One major area of the Computing and Telecommunications Division is Management Information Systems (MIS). A significant aspect of Management Information Systems' work is the development of proposals for new and enhanced administrative computing systems based on an analysis of informational needs. This document represent the outcome of the planning process for FY1991 through FY1993. The introduction of the FY1991 through FY1993 Long-Range Plan assesses the state of administrative computing at ANL and the implications of FY1991 funding recommendations. It includes a history of MIS planning for administrative data processing. This document discusses the strategy and goals which are an important part of administrative data processing plans for the Laboratory. It also describes the management guidelines established by the Administrative Data Processing Oversight Committee for the proposal and implementation of administrative computing systems. Summaries of the proposals for new or enhanced administrative computing systems presented by individual divisions or departments with assistance of Management Information Systems, to the Administrative Data Processing Oversight Committee are given. The detailed tables in this paper give information on how much the resources to develop and implement a given systems will cost its users. The tables include development costs, computing/operations costs, software and hardware costs, and efforts costs. They include both systems funded by Laboratory General Expense and systems funded by the users themselves.

  10. Administration by Objectives: A Systematic Approach to Educational Planning in Virginia. Report of a Study.

    ERIC Educational Resources Information Center

    Holmes, George W., III; Seawell, William H.

    This report presents (1) details of a program for educational administration by objectives and (2) the results of such a program developed by the Virginia State Department of Education to upgrade the quality of education in the public schools of that State. Administration by objectives is a systematic approach to education planning using…

  11. A&M. Plot plan of administration and A&M areas. Shows relationships ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Plot plan of administration and A&M areas. Shows relationships among administration buildings and to A&M building (TAN-607), railroad turntable. Ralph M. Parsons 902-2&3-ANP-U 3. Date: December 1952. INEEL index code no. 032-0100-00-693-106690 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  12. A PLAN FOR EDUCATIONAL POLICY AND ADMINISTRATIVE UNITS, FURTHER DECENTRALIZATION OF THE PUBLIC SCHOOLS.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY.

    THIS PLAN CONTAINS LEGISLATIVE PROPOSALS AND GENERAL RECOMMENDATIONS FOR THE DECENTRALIZATION OF THE NEW YORK CITY PUBLIC SCHOOLS AND FOR INCREASED PARENT AND COMMUNITY PARTICIPATION. IN PART IT RESPONDS TO AN EARLIER PLAN PROPOSED BY THE MAYOR'S PANEL ON DECENTRALIZATION. THE PRESENT PROPOSAL SUGGESTS THAT THE ADMINISTRATIVE RESTRUCTURING OF THE…

  13. 75 FR 48627 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Administrative and Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ...; Administrative and Non-Substantive Changes to Existing Delaware SIP Regulations AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA proposes to approve the State Implementation Plan (SIP... Implementation Plan (SIP). In the Final Rules section of this Federal Register, EPA is approving the State's...

  14. 29 CFR 4022.61 - Limitations on benefit payments by plan administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., a plan administrator files with the PBGC a notice of intent to terminate in a distress termination... a single life annuity at age 65. Because the participant is older than age 65, no adjustment is... participant who retired under a plan at age 60 is a reduced single life annuity of $400 per month plus...

  15. 29 CFR 4022.61 - Limitations on benefit payments by plan administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., a plan administrator files with the PBGC a notice of intent to terminate in a distress termination... a single life annuity at age 65. Because the participant is older than age 65, no adjustment is... participant who retired under a plan at age 60 is a reduced single life annuity of $400 per month plus...

  16. 29 CFR 4022.61 - Limitations on benefit payments by plan administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., a plan administrator files with the PBGC a notice of intent to terminate in a distress termination... a single life annuity at age 65. Because the participant is older than age 65, no adjustment is... participant who retired under a plan at age 60 is a reduced single life annuity of $400 per month plus...

  17. Photographic copy of architectural plan for Administration Building (T50): Taylor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural plan for Administration Building (T-50): Taylor & Barnes, Architects & Engineers, 803 W. Third Street, Los Angeles California, O.C.E. Office of Civil Engineer Job No. A(9-10), Military Construction: Materiel Command Flight Test Base, Muroc, California, Hangar and Auxiliary Buildings: Administration Building Type OB-H-T, Plans and - Details, Sheet No. 38 of 38, March 1944. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, Administration Building T-50, D Street, Boron, Kern County, CA

  18. Family planning needs: an empirical study of federal responsiveness before and during the Reagan administration.

    PubMed

    Mcfarlane, D R

    1988-01-01

    Arguing that the states would have "enhanced responsiveness to local needs," the Reagan administration proposed in 1981 to repeal some 40 categorical health programs, to reduce their funding, and replace them with block grants to the states. This responsiveness argument is examined within the context of the national family planning program, which was funded by several diverse federal grants and which serves 4,500,000 women each year. 3 questions are addressed: did experience prior to the Reagan Administration suggest that state administered, discretionary federal funds would be more responsive to individual state family planning needs than were federally administered categorical grants; how have the different types of grants performed during the Reagan Administration; and are state administered block grant programs more responsive to local needs than are other types of state administered federal grants. State expenditure data were used to examine the variation in the responses of different funding sources to states' needs for 2 periods: fiscal years 1976-81, the 6-year period prior to the Reagan Administration; and fiscal years 1982-83, the first 2 full budgetary years after Reagan assumed office. From fiscal 1976-81, Title V of the Social Security Act (the Maternal and Child Health Block Grant) annually contributed between 7-11% of all federal funds for family planning. The categorical program, Title X, was the largest single contributor to the federal family planning effort; its annual contribution ranged from 48-54% of all federal expenditures. The Medicaid program, Title XIX, accounted for the 2nd largest contribution to federal expenditures for family planning, ranging from 15-38%. Title XX funds, which were allocated to states on the basis of total population, accounted for 17-22% of all federal expenditures for family planning. It was hypothesized that: prior to the Reagan Administration, state administered federal grants were more responsive to states

  19. 76 FR 48941 - Notification of Petition for Approval; Product Safety Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ... Railroad Administration (FRA) approval of a Product Safety Plan (PSP) submitted pursuant to 49 CFR part 236... approval of a PSP for the Railsoft TrackAccess System. The TrackAccess System is a processor- based... productivity. Marquette asserts the PSP demonstrates that the TrackAccess System has been designed in a...

  20. 49 CFR 213.119 - Continuous welded rail (CWR); plan contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... arrangement in the CWR plans. (7) Specify the recordkeeping requirements related to joint bars in CWR... paragraphs (h)(1) through (h)(7) of this section, a track owner may seek approval from FRA to use alternate...)(1) through (h)(7) of this section, the Associate Administrator will approve the alternate...

  1. 49 CFR 213.119 - Continuous welded rail (CWR); plan contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... arrangement in the CWR plans. (7) Specify the recordkeeping requirements related to joint bars in CWR... paragraphs (h)(1) through (h)(7) of this section, a track owner may seek approval from FRA to use alternate...)(1) through (h)(7) of this section, the Associate Administrator will approve the alternate...

  2. 49 CFR 213.119 - Continuous welded rail (CWR); plan contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... arrangement in the CWR plans. (7) Specify the recordkeeping requirements related to joint bars in CWR... paragraphs (h)(1) through (h)(7) of this section, a track owner may seek approval from FRA to use alternate...)(1) through (h)(7) of this section, the Associate Administrator will approve the alternate...

  3. 131. ARAII Administration building (ARA613) floor plans for first and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    131. ARA-II Administration building (ARA-613) floor plans for first and second floors. Includes roof plan. Shows use of rooms as offices, laboratory, conference room. F.C. Torkelson Company 842-area/SL-1-613-A-1. Date: October 1958. Ineel index code no. 070-0613-00-851-150718. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  4. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1710-1755 MHz, 2110-2155 MHz, 2000-2020 MHz, and 2180-2200 MHz bands Cost-Sharing Policies Governing Broadband Radio Service Relocation from the 2150-2160/62 Mhz Band § 27.1178 Administration of the Cost-Sharing Plan. The Wireless...

  5. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1710-1755 MHz, 2110-2155 MHz, 2160-2180 MHz Bands Cost-Sharing Policies Governing Broadband Radio Service Relocation from the 2150-2160/62 Mhz Band § 27.1178 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau, under...

  6. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1695-1710 MHz, 1710-1755 MHz, 1755-1780 MHz, 2110-2155 MHz, 2155-2180 MHz, 2180-2200 MHz Bands Cost-Sharing Policies Governing Broadband Radio Service Relocation from the 2150-2160/62 Mhz Band § 27.1178 Administration of the Cost-Sharing Plan. The...

  7. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1710-1755 MHz, 2110-2155 MHz, 2160-2180 MHz Bands Cost-Sharing Policies Governing Broadband Radio Service Relocation from the 2150-2160/62 Mhz Band § 27.1178 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau, under...

  8. 42 CFR 441.745 - State plan HCBS administration: State responsibilities and quality improvement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false State plan HCBS administration: State responsibilities and quality improvement. 441.745 Section 441.745 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS SERVICES: REQUIREMENTS AND LIMITS APPLICABLE TO...

  9. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Administration of the Cost-Sharing Plan. 24.241 Section 24.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the...

  10. Attitudes of Employees of Provincial Directorates of National Education and School Administrators towards Strategic Planning

    ERIC Educational Resources Information Center

    Altinkurt, Yahya

    2010-01-01

    The aim of the study is to determine the attitudes of employees of Provincial Directorates of National Education and school administrators towards strategic planning. The research was designed as a survey model study. The population of the research consisted of employees of Provincial Directorate of National Education of Kutahya and school…

  11. Model Plan for Administration and Supervision Services. (Student Vocational Organization Coordinator.) Final Report.

    ERIC Educational Resources Information Center

    Wonser, Renee; Kohns, Donald

    Growing out of a project to improve administrative and support services for North Dakota student vocational organizations, this manual outlines possible duties and responsibilities of a state-level student vocational organizational coordinator based on a sequential planning and implementation system. The manual is divided into four areas with…

  12. 24 CFR 1000.236 - What are eligible administrative and planning expenses?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What are eligible administrative and planning expenses? 1000.236 Section 1000.236 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  13. 24 CFR 1000.236 - What are eligible administrative and planning expenses?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What are eligible administrative and planning expenses? 1000.236 Section 1000.236 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  14. 24 CFR 1000.236 - What are eligible administrative and planning expenses?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What are eligible administrative and planning expenses? 1000.236 Section 1000.236 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  15. 24 CFR 1000.236 - What are eligible administrative and planning expenses?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What are eligible administrative and planning expenses? 1000.236 Section 1000.236 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  16. 24 CFR 1000.236 - What are eligible administrative and planning expenses?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What are eligible administrative and planning expenses? 1000.236 Section 1000.236 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  17. Directory of National Institutions of Educational Planning and Administration in Asia and the Pacific. Second Edition.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

    This directory provides information about 27 institutions and organizations that offer in-service training and research and professional services in relation to educational planning and administration in 13 Asian and Pacific basin countries. The directory's objective is to generate and strengthen regional, inter-country, and inter-institutional…

  18. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Administration of the Cost-Sharing Plan. 24.241 Section 24.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the...

  19. 78 FR 9928 - Food and Drug Administration Drug Shortages Task Force and Strategic Plan; Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Drug Shortages Task Force and Strategic Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice; request for comments. SUMMARY: To assist the Food and Drug Administration (FDA or Agency) in drafting a strategic...

  20. 78 FR 15019 - Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice, request for comments. SUMMARY: The Food and Drug Administration (FDA or the Agency) is announcing...

  1. Photographic copy of foundation plans for Administration Building (T50), Operations ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of foundation plans for Administration Building (T-50), Operations Building (T-42), and Inflammable Storage Building (T-57): Taylor & Barnes, Architects & Engineers, 803 W. Third Street, Los Angeles California, O.C.E. Office of Civil Engineer Job No. A(9-10), Military Construction: Materiel Command Flight Test Base, Muroc, California, Hangar and Auxiliary Buildings: Administration Bldg Type OB-H-T, Operations Bldg Type OB-A-T, Inflammable Storage Bldg. Type WHSE 1-A (Mod.) Foundation Plans, Sheet No. 35 of 38, March 1944. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, Administration Building T-50, D Street, Boron, Kern County, CA

  2. A study of managerial style of the district family planning administrators.

    PubMed

    Nath, D H; Sapru, R

    1976-01-01

    In 1973-74, NIHAE, an organization established primarily to improve the general administration of health services by imparting inservice training in modern management concepts and techniques to senior health administrators in India, conducted a study to determine the training needs of district level family planning administrators, according to their actual managerial roles and functions and the problems and difficulties they face. 331 district family planning officials were mailed a Blake and Mouton grid questionnaire. 5 major styles located in the 4 corners and the mix point of the grid have been used as the representative managerial styles of 5 major sets of underlying assumptions. The distribution of district family planning administrators in 1973 is based upon a pooled estimate of around 286 of the 331 district family planning officers. Their managerial styles are as follows: 44.2% of the respondents revealed a managerial style that shows a high potential for team management and the ability to generate a climate of mutual interdependence, trust and confidence by integrating organizational purpose with the creation of sound and healthy human relationships; 2) 29.6% showed a style that focuses on the needs of people in an attempt to maintain interpersonal relationships leading to a friendly organizational climate and work tempo; 3) 10.7% represented the task management approach, showing primary concern for performance; 4) 12.2% strove to strike a balance between concern for performance and the human element; and 5) 5.4% of the managers showed a lack of concern for either task performance or human relationships. Although around 50% of the district family planning officers revealed managerial potential, the study findings indicate that individual respondents were dispersed in all the 5 typical styles, irrespective of age. However, the organizational pressures in existing State Health Administrations were by and large tending to make the officers resort to levels of

  3. 49 CFR 272.103 - Submission of critical incident stress plan for approval by the Federal Railroad Administration.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Submission of critical incident stress plan for... CRITICAL INCIDENT STRESS PLANS Plan Components and Approval Process § 272.103 Submission of critical incident stress plan for approval by the Federal Railroad Administration. (a) Each railroad subject to...

  4. Effect of contrast agent administration on consequences of dosimetry and biology in radiotherapy planning

    NASA Astrophysics Data System (ADS)

    Lo, Ching-Jung; Yang, Pei-Ying; Chao, Tsi-Chian; Tu, Shu-Ju

    2015-06-01

    In the treatment planning of radiation therapy, patients may be administrated with contrast media in CT scanning to assist physicians for accurate delineation of the target or organs. However, contrast media are not used in patients during the treatment delivery. In particular, contrast media contain materials with high atomic numbers and dosimetric variations may occur between scenarios where contrast media are present in treatment planning and absent in treatment delivery. In this study we evaluate the effect of contrast media on the dosimetry and biological consequence. An analytical phantom based on AAPM TG 119 and five sets of CT images from clinical patients are included. Different techniques of treatment planning are considered, including 1-field AP, 2-field AP+PA, 4-field box, 7-field IMRT, and RapidArc. RapidArc is a recent technique of volumetric modulated arc therapy and is used in our study of contrast media in clinical scenarios. The effect of RapidArc on dosimetry and biological consequence for administration of contrast media in radiotherapy is not discussed previously in literature. It is shown that dose difference is reduced as the number of external beams is increased, suggesting RapidArc may be favored to be used in the treatment planning enhanced by contrast media. Linear trend lines are fitted for assessment of percent dose differences in the planning target volume versus concentrations of contrast media between plans where contrast media are present and absent, respectively.

  5. 49 CFR Appendix C to Part 209 - FRA's Policy Statement Concerning Small Entities

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... hazardous materials shippers meeting the economic criteria established for Class III railroads in 49 CFR... described in Appendix A to 49 CFR part 209, it is FRA's policy to consider a variety of factors in... RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Pt. 209,...

  6. 49 CFR 240.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF... individual railroad programs by FRA. (a) Each railroad shall submit its written certification program and...

  7. 49 CFR 240.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF... individual railroad programs by FRA. (a) Each railroad shall submit its written certification program and...

  8. 49 CFR 240.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF... individual railroad programs by FRA. (a) Each railroad shall submit its written certification program and...

  9. 49 CFR 240.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF... individual railroad programs by FRA. (a) Each railroad shall submit its written certification program and...

  10. 49 CFR 240.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF... individual railroad programs by FRA. (a) Each railroad shall submit its written certification program and...

  11. Follow-up process evaluation of Bonneville Power Administration's energy savings plan program

    SciTech Connect

    Jennings, J.G.; Peters, J.S. )

    1990-01-01

    The Energy $avings Plan (E$P) program has been operated by the Bonneville Power Administration (Bonneville) since late fall 1987. The program is designed to build capability in the acquisition of conservation resources in the non-aluminum industrial sector in the Pacific Northwest. According to the Northwest Power Planning Council, the non-aluminum industrial sector accounts for about 23% of the total regional electricity consumption. Five non-aluminum industries consume 85% of this total. Three major industries --- chemical producers, pulp and paper plants, and lumber mills --- account for around 68% of non-aluminum industrial consumption (i.e., 16% of the total regional electricity consumption). 1 ref.

  12. 130. ARAII Administration building (ARA613) vicinity map and plot plan ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    130. ARA-II Administration building (ARA-613) vicinity map and plot plan showing relationship to other existing buildings on site and to ARA-602, to which this building was attached. F.C. Torkelson Comapny 842-area/SL-1-101-U-1. Date: October 1959. Ineel index code no. 070-0101-65-851-150053. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  13. Health maintenance organizations; Midwest Health Plan--Health Resources and Services Administration.

    PubMed

    1983-04-26

    On January 21, 1983, the Office of Health Maintenance Organizations (OHMO) notified Midwest Health Plan (MHP), 3415 Bridgeland Drive, Bridgeton, Missouri 63044, a federally qualified health maintenance organization (HMO), that MHP had successfully reestablished compliance with its assurances to the Secretary that it would (1) maintain a fiscally sound operation, and (2) maintain satisfactory administrative and managerial arrangements. This determination took effect on January 1, 1983. PMID:10324428

  14. Strategic plan for geriatrics and extended care in the veterans health administration: background, plan, and progress to date.

    PubMed

    Shay, Kenneth; Hyduke, Barbara; Burris, James F

    2013-04-01

    The leaders of Geriatrics and Extended Care (GEC) in the Veterans Health Administration (VHA) undertook a strategic planning process that led to approval in 2009 of a multidisciplinary, evidence-guided strategic plan. This article reviews the four goals contained in that plan and describes VHA's progress in addressing them. The goals included transforming the healthcare system to a veteran-centric approach, achieving universal access to a panel of services, ensuring that the Veterans Affair's (VA) healthcare workforce was adequately prepared to manage the needs of the growing elderly veteran population, and integrating continuous improvement into all care enhancements. There has been substantial progress in addressing all four goals. All VHA health care has undergone an extensive transformation to patient-centered care, has enriched the services it can offer caregivers of dependent veterans, and has instituted models to better integrate VA and non-VA cares and services. A range of successful models of geriatric care described in the professional literature has been adapted to VA environments to gauge suitability for broader implementation. An executive-level task force developed a three-pronged approach for enhancing the VA's geriatric workforce. The VHA's performance measurement approaches increasingly include incentives to enhance the quality of management of vulnerable elderly adults in primary care. The GEC strategic plan was intended to serve as a road map for keeping VHA aligned with an ambitious but important long-term vision for GEC services. Although no discrete set of resources was appropriated for fulfillment of the plan's recommendations, this initial report reflects substantial progress in addressing most of its goals. PMID:23527829

  15. Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival

    PubMed Central

    Iskit, Sedef; Schlicker, Andreas; Wessels, Lodewyk; Peeper, Daniel S.

    2015-01-01

    Fra-1 (Fos-related antigen-1) is a member of the AP-1 (activator protein-1) family of transcription factors. We previously showed that Fra-1 is necessary for breast cancer cells to metastasize in vivo, and that a classifier comprising genes that are expressed in a Fra-1-dependent fashion can predict breast cancer outcome. Here, we show that Fra-1 plays an important role also in colon cancer progression. Whereas Fra-1 depletion does not affect 2D proliferation of human colon cancer cells, it impairs growth in soft agar and in suspension. Consistently, subcutaneous tumors formed by Fra-1-depleted colon cancer cells are three times smaller than those produced by control cells. Most remarkably, when injected intravenously, Fra-1 depletion causes a 200-fold reduction in tumor burden. Moreover, a Fra-1 classifier generated by comparing RNA profiles of parental and Fra-1-depleted colon cancer cells can predict the prognosis of colon cancer patients. Functional pathway analysis revealed Wnt as one of the central pathways in the classifier, suggesting a possible mechanism of Fra-1 function in colon cancer metastasis. Our results demonstrate that Fra-1 is an important determinant of the metastatic potential of human colon cancer cells, and that the Fra-1 classifier can be used as a prognostic predictor in colon cancer patients. PMID:26646695

  16. Expanding ADA coverage to employee benefit plans: recent judicial and administrative developments.

    PubMed

    Mook, J R

    1995-01-01

    The Americans with Disabilities Act has been heralded as the Emancipation Proclamation for persons with disabilities. The purpose of the law is to provide nothing less than a "clear and comprehensive national mandate for the elimination of discrimination against individuals with disabilities." Precisely how the nondiscrimination principles of the ADA will be applied to an employer's provision of health benefits to its employees has been the subject of much debate since the Act's passage in 1990. Although the statutory language and the legislative history support a limited application of the ADA to benefits issues, recent court decisions and enforcement actions by the Equal Employment Opportunity Commission indicate that the ADA may have a much more profound impact in the area of benefits plan design and administration. Moreover, as benefits administrators take a much more active role in managing health care decisions, the ADA may become a vehicle for legal challenges to those decisions that affect the disabled. PMID:10172245

  17. Serving the Needs of Struggling Developmental Education Students: The Development of a Program Planning Guidebook for Community College Administrators

    ERIC Educational Resources Information Center

    Bohnet, Kimberly Jean

    2016-01-01

    This dissertation describes the process of creating a guidebook that developmental education administrators can use to build their capacity as leaders, learners, and program planners. The guidebook is the product of a qualitative study designed to better understand how community college administrators who have program planning responsibilities for…

  18. A Plan of Organization, Administration, and Elements of Finance for Vocational-Technical Adult Education, Birmingham City School System.

    ERIC Educational Resources Information Center

    Shelton, John Alton

    Designed to help formulate a plan of organization and administration for vocational and technical education and adult education in the Birmingham, Alabama, city schools, this study entailed an extensive literature review on vocational education and administrative matters; a historical review of several Birmingham schools (Paul Hayne School,…

  19. Planning and Delivering Instruction with Increasing Class Sizes in Educational Administration Program Coursework: Modeling Leadership Skills for New Professors Transitioning from K-12 Administration

    ERIC Educational Resources Information Center

    Stebbins, Gary

    2009-01-01

    Increased class sizes and advising responsibilities are the new realities in California's graduate programs of Educational Administration. In order to effectively meet new challenges, professors must make adjustments in venue, plan meticulously, utilize technology, distribute leadership, and implement alternative grading systems. This is a…

  20. Brief Report: Effects of an Administrative Supervisory Protocol on Preparation of Behavior Support Plans at a Child Service Setting

    ERIC Educational Resources Information Center

    Garrity, Meredith L.; Luiselli, James K.

    2005-01-01

    We evaluated a supervisory protocol that targeted preparation of behavior support plans by administrative staff at a school for children with developmental disabilities. Using a multiple baseline design, the protocol was applied sequentially to three components of behavior support plan preparation. Intervention procedures included goal…

  1. Comprehensive Planning or Vocational Education. A Guide for Administrators. [8th Yearbook of the American Vocational Association].

    ERIC Educational Resources Information Center

    Lamar, Carl S., Ed.

    This book was designed to serve as a guide for vocational education administrators in implementing comprehensive program planning (the process of forecasting the future and then preparing for it) as called for in the Education Amendments of 1976. The content is presented in ten chapters. The first provides an overview of comprehensive planning in…

  2. 29 CFR 2520.103-5 - Transmittal and certification of information to plan administrator for annual reporting purposes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (Insurance Carrier) hereby certifies that the foregoing statement furnished pursuant to 29 CFR 2520.103-5(c... 29 Labor 9 2010-07-01 2010-07-01 false Transmittal and certification of information to plan... Report Requirements § 2520.103-5 Transmittal and certification of information to plan administrator...

  3. Work management administration FY 1995 site support program plan WBS 6.2

    SciTech Connect

    Hale, N.S.

    1994-09-01

    Westinghouse Hanford Company`s (WHC) near-term vision is to implement a Site-wide work management program that is consistent from one facility to the other, and can realize workforce efficiencies, minimum down time, and familiarization with facilities uniqueness. Additionally, consistent Hanford Site work management processes can produce meaningful information to be shared complex-wide as the US Department of Energy (DOE) cleans up facilities Site-wide. It is the mission of the WHC Work Management Administration Program to provide guidance and program direction on how to implement consistent and effective work management across the Hanford Site that comply with the DOE and other regulatory requirements. This report describes the steps needed to implement a work management plan at Hanford.

  4. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    SciTech Connect

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA's Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  5. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    SciTech Connect

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA`s Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  6. 20 CFR 1002.167 - What actions may a plan administrator take if the employee does not elect or pay for continuing...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What actions may a plan administrator take if... Uniformed Services Health Plan Coverage § 1002.167 What actions may a plan administrator take if the... may take regarding the provision or cancellation of an employee's continuing coverage depend...

  7. 45 CFR 400.9 - Administrative review of decisions on approval of State plans and plan amendments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State...

  8. 45 CFR 400.9 - Administrative review of decisions on approval of State plans and plan amendments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State...

  9. 45 CFR 400.9 - Administrative review of decisions on approval of State plans and plan amendments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State...

  10. 45 CFR 400.9 - Administrative review of decisions on approval of State plans and plan amendments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State...

  11. 45 CFR 400.9 - Administrative review of decisions on approval of State plans and plan amendments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State...

  12. Morphine administration by Paramedics: an application of the Theory of Planned Behaviour.

    PubMed

    Weber, Anthony; Dwyer, Trudy; Mummery, Kerry

    2012-09-01

    Timely and appropriate pain management in the pre-hospital environment is paramount to effective patient care. Experts agree that there are many factors that hinder the delivery of adequate pain management to patients with pain. The purpose of this study was to use the Theory of Planned Behaviour (TPB) model to identify the factors influencing Ambulance Paramedics' intention to administer morphine to patients with pain. Participants of this study were Advanced Care and Intensive Care Paramedics who were deemed competent in morphine administration. Data were collected by means of a questionnaire that used the constructs of the TPB, including subjective norm, perceived behavioural control and attitude. Whilst participants reported strong intentions to administer morphine they also reported negative attitudes towards the behaviour. The constructs of the TPB explained 26% of the variance in intention to administer morphine with subjective norm being the strongest significant predictor. The findings related to specific attitudes and normative pressures provide an understanding into Paramedic's pain management behaviour. PMID:21215396

  13. Manpower Planning Data: Selected Professional and Administrative Career Fields: 1966-1970 Trends, 1971-1975 Projections.

    ERIC Educational Resources Information Center

    Veterans Administration, Washington, DC.

    This report provides 5-year (1966-1970) trends for the following manpower planning factors: number of employees in each career field, grade distribution, age, length of service, education, employment of women, promotions, retirement, and losses. These data are intended as an aid to Veterans Administration (VA) management in assessing future…

  14. Developing "Green" Business Plans: Using Entrepreneurship to Teach Science to Business Administration Majors and Business to Biology Majors

    ERIC Educational Resources Information Center

    Letovsky, Robert; Banschbach, Valerie S.

    2011-01-01

    Biology majors team with business administration majors to develop proposals for "green" enterprise for a business plan competition. The course begins with a series of student presentations so that science students learn about the fundamentals of business, and business students learn about environmental biology. Then mixed biology-business student…

  15. Administrators and Researchers -- Coworkers in University Planning. A Case Study of a Successful Cooperative Venture in Research.

    ERIC Educational Resources Information Center

    Crouch, Kathleen; And Others

    A cooperative effort by administrators and institutional researchers to assess the public image of an institution of higher education as one step in the planning process is described. Discussed are the interpersonal dynamics occurring in the recognition of the general problem, the formulation of specific questions, the design of the survey…

  16. Employment Training Panel: Has Achieved Many of Its Training Program Responsibilities Despite Some Administrative and Planning Problems.

    ERIC Educational Resources Information Center

    California State Office of the Auditor General, Sacramento.

    California's Employment Training Panel was created in 1982 to work in partnership with the state's businesses, labor unions, and government to provide training funds to California businesses. In 1995, the Employment Training Panel's administrative practices, strategic planning efforts, and contracting policies and practices/procedures were…

  17. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  18. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  19. 24 CFR 1000.239 - May a recipient establish and maintain reserve accounts for administration and planning?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false May a recipient establish and maintain reserve accounts for administration and planning? 1000.239 Section 1000.239 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  20. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT...

  1. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  2. 24 CFR 1000.239 - May a recipient establish and maintain reserve accounts for administration and planning?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false May a recipient establish and maintain reserve accounts for administration and planning? 1000.239 Section 1000.239 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  3. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT...

  4. The Relationship between Funding, ICT, Selection Processes, Administration and Planning and the Standard of Science Teacher Education in Nigeria

    ERIC Educational Resources Information Center

    Ololube, Nwachukwu Prince

    2007-01-01

    This study was motivated by the premise that no nation grows further than the quality of its education. The paper presents an investigation on the relationships between funding, ICT, selection processes, administration and planning and the standard of science teacher education in Nigeria. The data for the study was gathered through a two page…

  5. 29 CFR 2590.606-4 - Notice requirements for plan administrators.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the Social Security Administration, under title II or XVI of the Social Security Act (42 U.S.C. 401 et... disability by the Social Security Administration regarding a covered employee, qualified beneficiary,...

  6. 29 CFR 2590.606-4 - Notice requirements for plan administrators.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Social Security Administration, under title II or XVI of the Social Security Act (42 U.S.C. 401 et... disability by the Social Security Administration regarding a covered employee, qualified beneficiary,...

  7. 29 CFR 2590.606-4 - Notice requirements for plan administrators.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Social Security Administration, under title II or XVI of the Social Security Act (42 U.S.C. 401 et... disability by the Social Security Administration regarding a covered employee, qualified beneficiary,...

  8. 29 CFR 2590.606-4 - Notice requirements for plan administrators.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Social Security Administration, under title II or XVI of the Social Security Act (42 U.S.C. 401 et... disability by the Social Security Administration regarding a covered employee, qualified beneficiary,...

  9. Evaluation and recommendations for the Department of Energy-Farmers Home Administration small-town energy-planning grant program

    SciTech Connect

    Cannon, T.; Kron, N. Jr.

    1980-10-01

    DOE funded several small-town energy planning projects, through the Farmer's Home Administration (FmHA) Area Development Assistance Planning Grant Program. DOE intended that this program should: (1) encourage community energy planning and the development of Integrated Community Energy Systems (ICES) and (2) provide a testing ground for the technologies and planning methods developed by its Buildings and Community Systems Division. FmHA intended that the joint program should further the development of rural areas and make DOE expertise available to grant recipients doing energy planning. All grantees under this joint program endeavored to define their local energy problems and to find local solutions. However, the resulting energy cost savings were not always impressive, and generally they were not very well documented. Lack of implementation power, lack of focus, and inability to generate local financial support for projects and further planning were the main reasons for this performance. The lack of sufficient documentation could be the result of DOE's failure to require a standardized and systematic accounting of grantees' accomplishments. The recommended changes in the scope-of-work requirements suggested in this report would cause grantees to focus their energy-planning activities so as to increase local financial support. The appendixes give a standardized format by which grantees would account for the energy savings and production made possible by their planning efforts.

  10. Study of Educational Hospital Employees’ Satisfaction with the Administration of the Health Reform Plan in Ghazvin, 2015

    PubMed Central

    Gholami, Soheyla; Oveisi, Sonia; Ghamari, Fatemeh; Etedal, Mahboobeh Ghorban; Rajaee, Roya

    2015-01-01

    Introduction Employee satisfaction is considered to be an important component in the promotion of service quality and increased efficiency and effectiveness in the reform plan for a healthcare system. Neglecting this issue could result in a lack of success in achieving the healthcare system’s objectives. The healthcare reform plan is being implemented to achieve the objectives of the healthcare system. Thus, given the key role of hospital employees in implementing the reform plan, the aim of this study was to determine the levels of hospital employees’ satisfaction with their jobs. Methods This was a qualitative study in 2015 that included thematic analysis, and 138 employees of the Kosar, Rajaii, and Ghods Hospitals participated. Data were collected using semi-structured interviews, and the data were analyzed using content analysis. Results After analyzing the data collected by interviewing the employees, 132 codes were identified. The codes were classified into five general concepts including opinions about 1) the reform plan and its administrative barriers, 2) changes in visits, 3) changes in working conditions, 4) changes in salaries and 5) General satisfaction of personnel. Conclusion Increasing workloads, stagnant salaries, and the shortage of personnel were the main factors that reduced the satisfaction of the hospitals’ employees with the administration of the healthcare reform plan. PMID:26767104

  11. 78 FR 38878 - Critical Incident Stress Plans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... report prepared by FRA grantee, Dr. Richard Gist, in support of Grant FR-RRD-0024-11- 01, titled... Administrator of FRA on rulemakings and other safety program issues. 61 FR 9740 (Mar. 11, 1996). RSAC's charter under the Federal Advisory Committee Act (Pub. L. 92-463) was most recently renewed in 2012. 77 FR...

  12. 77 FR 22949 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ...This proposed rule would implement section 1104 of the Patient Protection and Affordable Care Act (hereinafter referred to as the Affordable Care Act) by establishing new requirements for administrative transactions that would improve the utility of the existing Health Insurance Portability and Accountability Act of 1996 (HIPAA) transactions and reduce administrative burden and costs. It......

  13. Experimental Investigation on FRA Diagnosis of Transformer Faults

    NASA Astrophysics Data System (ADS)

    Sano, Takahiro; Miyagi, Katsunori

    The need for economical, reliable and effective delivery of electric power leads to the search for new, efficient and effective methods for diagnosing the high voltage equipments in the industries all over the world. As the average usage period of transformers increases, the necessity to know the internal condition of transformers is increasing. It is therefore critically important to establish monitoring and diagnostic techniques that can perform transformer condition assessment. Frequency response analysis, generally known as FRA, is one of the technologies to diagnose transformers. Using case studies, this paper presents the effectiveness of FRA as measurements for detecting transformer faults. This paper introduces the fact that FRA waveforms have useful information about diagnosis of fault on winding shield and core earths, and that the condition outside transformers can affect frequency response characteristics. The FRA measurement results are further investigated through a simulation study using a computer model.

  14. Future plans by the National Oceanic and Atmospheric Administration for operational geosynchronous weather satellites

    NASA Technical Reports Server (NTRS)

    Gird, Ronald S.; Shenk, William E.

    1991-01-01

    The present status of the GOES program and plans for the GOES I-M system schedules for initial launch in 1992 are reviewed. Plans for improving NASA's capabilities to monitor weather patterns by using operational geosynchronous weather satellites are considered. The requirements for the imager, sounder, Space Environment Monitor, and Data Collection System of GOES-N are presented.

  15. Administrative Guidelines: Education of Gifted Students [and] Plan for Education of the Gifted in South Dakota.

    ERIC Educational Resources Information Center

    South Dakota State Dept. of Education and Cultural Affairs, Pierre.

    This document is intended to assist South Dakota schools in the development and implementation of Gifted Education Plans, and includes state laws and rules pertaining to gifted education, guidelines for reporting, and explanations of the necessary components of a district's written plan. A brief statement of philosophy addresses characteristics of…

  16. Library Web Site Administration: A Strategic Planning Model For the Smaller Academic Library

    ERIC Educational Resources Information Center

    Ryan, Susan M.

    2003-01-01

    Strategic planning provides a useful structure for creating and implementing library web sites. The planned integration of a library's web site into its mission and objectives ensures that the library's community of users will consider the web site one of the most important information tools the library offers.

  17. Supporting Data Use among Administrators: Results from a Data Planning Model.

    ERIC Educational Resources Information Center

    Khanna, Ritu; Trousdale, Donna; Penuel, William R.; Kell, Judy

    The initiatives taken by one school district to support professional development for principals in using data for school planning and reform were studied. A data-planning training model was developed in the San Francisco Unified School District (SFUSD) (California) to build skills principals need to read, interpret, and use multiple sources of…

  18. OCLC for the hospital library: the justification plan for hospital administration.

    PubMed

    Allen, C W; Branson, J R

    1982-07-01

    This paper delineates the necessary steps to provide hospital administrators with the information needed to evaluate an automated system, OCLC, for addition to the medical library. Based on experience at the Norton-Children's Hospitals, included are: (1) cost analyses of present technical processing systems and cost comparisons with OCLC; (2) delineation of start-up costs for installing OCLC; (3) budgetary requirements for 1981; (4) the impact of automation on library systems, personnel, and services; (5) potential as a shared service; and (6) preparation of the proposal for administrative review. PMID:7116018

  19. China Education Almanac (1949 - 1981): The Planned Administration of Education, Educational Funds, and Wage System.

    ERIC Educational Resources Information Center

    Rosen, Stanley, Ed.

    1986-01-01

    This issue provides topics and titles of contemporary reference works on Chinese education. Most of the material provided is translated from pages 88 through 114 of the China Education Almanac, and describes the administration and funding of general education in China. (JDH)

  20. 29 CFR 2580.412-3 - Plan administrators, officers and employees for purposes of section 13.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY BONDING RULES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 TEMPORARY BONDING RULES Criteria for Determining Who Must Be Bonded § 2580...) For purposes of the bonding provisions, the term “administrator” is defined in the same manner...

  1. Training Administrators to Serve as Student Mentors: An Untapped Resource in Retention Planning.

    ERIC Educational Resources Information Center

    Martin, James; Samels, James E.

    1993-01-01

    Mount Ida College (Massachusetts) has found the use of college administrators as mentors to students, complementing academic advising and faculty mentoring, to be an effective approach to strengthening the tie between first-year college students and their institutions. The impact has been noticeable in the campus culture as well as in student…

  2. Financial Planning for Libraries. Second Edition. The Library Administration Series, No. 8.

    ERIC Educational Resources Information Center

    Prentice, Ann E.

    This new edition retains the underlying principles which distinguished the earlier volume: the impact of the economic environment on libraries, the interrelations of financial and service planning, attention to budgeting, and realistic appraisal of the prospects for the support of libraries. Added to this foundation are the economic and…

  3. Post-Implementation Success Factors for Enterprise Resource Planning Student Administration Systems in Higher Education Institutions

    ERIC Educational Resources Information Center

    Sullivan, Linda; Bozeman, William

    2010-01-01

    Enterprise Resource Planning (ERP) systems can represent one of the largest investments of human and financial resources by a higher education institution. They also bring a significant process reengineering aspect to the institution and the associated implementation project through the integration of compiled industry best practices into the…

  4. 29 CFR 4022.61 - Limitations on benefit payments by plan administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... higher benefit. (e) PBGC authority to modify procedures. In order to avoid abuse of the plan termination... difference between the participant and the beneficiary is computed under § 4022.23(e). In computing the difference in ages, years over 65 years of age are not taken into account. Therefore, the age difference is...

  5. K-12 Planning Guide for Videodisc Usage for Teachers and Administrators. 1995 Edition.

    ERIC Educational Resources Information Center

    Brumbaugh, Ken

    This guide is intended for K-12 educators who are planning to implement videodisc technology into a school's educational curriculum. Teachers need expertise in two areas for the success of interactive video in schools. First, they need to be able to integrate videodisc materials into existing curricula. Second, they need skills for reviewing,…

  6. Guidelines for developing NASA (National Aeronautics and Space Administration) ADP security risk management plans

    NASA Technical Reports Server (NTRS)

    Tompkins, F. G.

    1983-01-01

    This report presents guidance to NASA Computer security officials for developing ADP security risk management plans. The six components of the risk management process are identified and discussed. Guidance is presented on how to manage security risks that have been identified during a risk analysis performed at a data processing facility or during the security evaluation of an application system.

  7. 77 FR 54663 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... entity identifier (OEID), or an identifier for entities that are not health plans, health care providers... specifies the circumstances under which an organization covered health care provider must require certain noncovered individual health care providers who are prescribers to obtain and disclose a National...

  8. Federal Transit Administration strategic plan 1998--2002. People moving people into America`s future

    SciTech Connect

    1998-03-01

    The plan highlights the fact the transit is a critical element of an efficient transportation system, providing basic mobility for millions of Americans as well as congestion relief, reduced air and noise pollution, better land use patterns, and more livable communities. FTA`s Strategic Plan focuses on developing and utilizing a skilled and diverse workforce along with the latest information management and technological advances to fully exploit the benefits of transit. The report begins with a brief discussion of FTA`s vision, mission, core values and five strategic goals -- Safety and Security; Mobility and Accessibility; Economic Growth and Trade; Human and Natural Environment; and Quality Organization. Each strategic goal is customer oriented and discussed separately in terms of its outcome and performance goals as well as performance measures. The report also discusses the impact of current trends and transportation and implication for FTA programs, along with factors affecting achievement of FTA`s outcome and performance goals.

  9. National Aeronautics and Space Administration FY 02 Revised Final Annual Performance Plan

    NASA Astrophysics Data System (ADS)

    2002-01-01

    The Government Performance and Results Act (GPRA) was passed by Congress and signed by the President in 1993. GPRA was enacted to improve the efficiency of all Federal agencies, with the following specific goals: (1) Improve Federal program management, effectiveness, and public accountability; (2) Improve Congressional decision making on where to commit the Nation's financial and human resources; and (3) Improve citizen confidence in government performance. GPRA directs Executive Branch agencies to develop a customer-focused strategic plan that aligns activities with concrete missions and goals. The Act directs agencies to manage and measure results to justify Congressional appropriations and authorizations. The Report Consolidation Act of 2000 directs agencies to provide a report on the degree of success in achieving the goals and performance measures defined in the strategic and performance plans one hundred and fifty days after the completion of the fiscal year.

  10. 75 FR 61552 - Federal Railroad Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Railroad Administration Notice of Informational Filing In accordance with Section 236.913 of Title... Administration (FRA) has received an informational filing from the Northeast Illinois Regional Commuter...

  11. A plan for the delegation of epinephrine administration in nonpublic schools to unlicensed assistive personnel.

    PubMed

    Truglio-Londrigan, Marie; Macali, Margaret K; Bernstein, Marilynn; Kaider, Gina; Petersen, Susannah; Tumino, Maria Celeste

    2002-01-01

    Professional nurses in nonpublic schools address variables in their practice that are different from nurses in a public school setting. These may include lack of funds for full-time nursing, different educational requirements, incorporation of religious beliefs into the social milieu, and inadequate peer or union support. These variables are problematic when public law health statues require change in school/parent/student relationships. New Jersey's Public Law 1997, Chapter 368 (N.J.S.A. 18A:40-12.5 and 12.6), hereafter referred to as P.L. 1997, c. 368, was enacted because school nurses may not always be available to assess students who are experiencing severe allergic reactions. Since allergies in the school population are common and can lead to anaphylaxis which is life threatening (Smith, 1999), P.L. 1997, c. 368, requires each educational board or chief school administrator/principal of public and nonpublic schools to develop a policy governing epinephrine administration. This article describes how public health nurses, the director of public health nursing, and a faculty consultant in the Bergen County Department of Health Services worked together to produce strategies for the safe implementation of this law. These strategies may provide a template for consideration by other public health nurses who serve the student population. PMID:12406176

  12. Bonneville Power Administration Fish & Wildlife Implementation Plan Final Environmental Impact Statement

    SciTech Connect

    N /A

    2003-05-09

    The Pacific Northwest has long prided itself on its bountiful and diverse natural resources--its forests and grasslands, minerals and rivers, fish and wildlife. The Region has also relied on these natural resources to serve multiple, and sometimes conflicting, uses. The independent demands of the whole spectrum of human uses (such as irrigation, municipal water supplies, grazing, fishing and hunting, electric power production, recreation, timber harvest, and transportation) have placed increasing stress on the natural resources of the Columbia River Basin. One consequence is that, over the last decade, the number of fish and wildlife species listed as endangered or threatened under the Endangered Species Act (ESA) has dramatically increased. The Region has sought to stem and even reverse the species decline. Unfortunately, after a decade of good intentions, there has been less progress than is necessary to reverse this trend. Here are the most important reasons: (1) Different groups have different value judgments about priorities, leading to different (and often conflicting) ideas about what recovery and mitigation efforts should be. (2) There is no clear and agreed-upon scientific answer to the problem. (3) Conflicting directives and jurisdictions of regional authorities have meant that funds dedicated to fish and wildlife mitigation and recovery efforts have often been used less efficiently and effectively than they otherwise could have been. Recently, regional entities have taken steps to work together to develop a comprehensive and coordinated planning approach for species recovery and mitigation. For example, over the past several years the Council's Columbia River Basin Fish and Wildlife Program, the Recommendations for the Protection and Restoration of Fish In The Columbia River Basin by the Governors of the four Northwestern States, and the Federal Caucus' Conservation of Columbia Basin Fish: Final Basinwide Salmon Recovery Strategy (Basinwide Strategy

  13. 20 CFR 1002.167 - What actions may a plan administrator take if the employee does not elect or pay for continuing...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Omnibus Budget Reconciliation Act of 1985, 26 U.S.C. 4980B (COBRA), it may be reasonable for a health plan administrator to adopt COBRA-compliant rules regarding election of continuing coverage, as long as those rules... cancellation of coverage if timely payment is not made. Where health plans are covered under COBRA, it may...

  14. 20 CFR 1002.167 - What actions may a plan administrator take if the employee does not elect or pay for continuing...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Omnibus Budget Reconciliation Act of 1985, 26 U.S.C. 4980B (COBRA), it may be reasonable for a health plan administrator to adopt COBRA-compliant rules regarding election of continuing coverage, as long as those rules... cancellation of coverage if timely payment is not made. Where health plans are covered under COBRA, it may...

  15. 20 CFR 1002.167 - What actions may a plan administrator take if the employee does not elect or pay for continuing...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Omnibus Budget Reconciliation Act of 1985, 26 U.S.C. 4980B (COBRA), it may be reasonable for a health plan administrator to adopt COBRA-compliant rules regarding election of continuing coverage, as long as those rules... cancellation of coverage if timely payment is not made. Where health plans are covered under COBRA, it may...

  16. 20 CFR 1002.167 - What actions may a plan administrator take if the employee does not elect or pay for continuing...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Omnibus Budget Reconciliation Act of 1985, 26 U.S.C. 4980B (COBRA), it may be reasonable for a health plan administrator to adopt COBRA-compliant rules regarding election of continuing coverage, as long as those rules... cancellation of coverage if timely payment is not made. Where health plans are covered under COBRA, it may...

  17. The use of Metro-Apex in health administration and planning education and training.

    PubMed

    Washburn, A W; McGinty, R T

    1977-01-01

    Metro-Apex is a computerized gaming-simulation designed to give practitioners and students an understanding of the environment of health care delivery systems. The exercise allows participants to explore the interaction of health roles and the health system's interaction with the larger community system. Originally developed as an air pollution control exercise, it has evolved to be a game about communities and how they operate. In 1972, the Department of Health, Education, and Welfare funded the Center for Multidisciplinary Educational Exercises (COMEX), of the University of Southern California to modify Metro-Apex for use with health service planners, health care administrators, and students in programs leading to these positions. The game runs in several rounds of from three to eight hours for groups of from 40 to 120 persons. Used in both educational and training settings, Metro-Apex is found to be a flexible addition to the health educator's tools. PMID:870456

  18. Administrative politics in the Ohio Department of Energy: the regulation of electric utility strategic planning

    SciTech Connect

    Stroup, K.M.

    1984-01-01

    The study examines political behavior manifested by several regulatory and quasi-regulatory state agencies in the development and implementation of a procedure to review electric utility long-range forecasts of demand and resources. The analysis identifies the political issues which orient political behavior during the development and implementation of the forecast evaluation process, and examines the social and cultural resources that various actors manipulate in pursuit of support for their political goals. A processual framework is employed to trace actors' dynamic manipulative strategies, including those involving the manipulation of cultural forms such as myth and ideology. The research results suggest that bureaucratic agencies are adept at manipulating social and cultural forms in their pursuit of legislative and administrative support for their political goals.

  19. Developing Items to Measure Theory of Planned Behavior Constructs for Opioid Administration for Children: Pilot Testing.

    PubMed

    Vincent, Catherine; Riley, Barth B; Wilkie, Diana J

    2015-12-01

    The Theory of Planned Behavior (TpB) is useful to direct nursing research aimed at behavior change. As proposed in the TpB, individuals' attitudes, perceived norms, and perceived behavior control predict their intentions to perform a behavior and subsequently predict their actual performance of the behavior. Our purpose was to apply Fishbein and Ajzen's guidelines to begin development of a valid and reliable instrument for pediatric nurses' attitudes, perceived norms, perceived behavior control, and intentions to administer PRN opioid analgesics when hospitalized children self-report moderate to severe pain. Following Fishbein and Ajzen's directions, we were able to define the behavior of interest and specify the research population, formulate items for direct measures, elicit salient beliefs shared by our target population and formulate items for indirect measures, and prepare and test our questionnaire. For the pilot testing of internal consistency of measurement items, Cronbach alphas were between 0.60 and 0.90 for all constructs. Test-retest reliability correlations ranged from 0.63 to 0.90. Following Fishbein and Ajzen's guidelines was a feasible and organized approach for instrument development. In these early stages, we demonstrated good reliability for most subscales, showing promise for the instrument and its use in pain management research. Better understanding of the TpB constructs will facilitate the development of interventions targeted toward nurses' attitudes, perceived norms, and/or perceived behavior control to ultimately improve their pain behaviors toward reducing pain for vulnerable children. PMID:26527107

  20. Safety and quality management and administration Fiscal Year 1995 site support program plan WBS 6.7.2.6

    SciTech Connect

    Hagan, J.W.

    1994-09-01

    The mission of the Emergency, Safety, and Quality Services (ESQ) management and Program Integration is to provide leadership for the ESQ Department, coordinate business management activities of the ESQ department, and the programs it supports, as well as to plan organize, direct, and control other activities that require department-wide coordination. Primary activities include providing strategic and business planning and reporting support to ESQ management; developing and documenting ESQ management systems and procedures; coordinating ESQ`s self-assessment and Award Fee self evaluation efforts; coordinating the ESQ departments`s communication, total quality, cost savings, and productivity efforts; and tracking ESQ commitments and staffing data. This program element also provides program direction and performance assessment for the ESH&Q division of ICF KH. The ESH&Q Division educates ICF KH management and employees to protect personnel and the environment; identifies, interprets and inspects to requirements; provides administrative and field support; performs final acceptance of construction; assesses effectiveness of ICF KH programs and processes, and performs baseline ESH&Q assessments.

  1. Administrator Succession Planning

    ERIC Educational Resources Information Center

    Wilson, Jackie

    2009-01-01

    The Delaware Department of Education, in collaboration with the Delaware Academy for School Leadership at the University of Delaware, has been the recipient of Wallace Foundation funding since 2000 as part of the foundation's initiative to develop and share ideas for strengthening education leadership. The grant has enabled the state education…

  2. Guidelines and workbook for assessment of organization and administration of utilities seeking operating license for a nuclear power plant. Guidelines for utility organization and administration plan. Volume 1, Revision 1

    SciTech Connect

    Thurber, J.A.; Olson, J.; Osborn, R.N.; Sommers, P.; Widrig, R.D.

    1986-09-01

    Volumes 1 and 2 of this report are a partial response to the requirements of Item I.B.1.1 of the ''NRC Action Plan Developed as a Result of the TMI-2 Accident,'' NUREG-0660, and are designed to serve as a basis for replacing the earlier NUREG-0731, ''Guidelines for Utility Management Structure and Technical Resources.'' These Guidelines are intended to provide guidance to the user in preparing a written plan for a proposed nuclear organization and administration. The purpose of the Workbook (Vol. 2) is to guide the NRC reviewer through a systematic review and assessment of a proposed organization and administration. It is the NRC's intention to incorporate these Guidelines and Workbook into a future revision of the Standard Review Plan (SRP), NUREG-0800. However, at this time the report is being published so that the material may be used on a voluntary basis by industry to systematically prepare or evaluate their organization or administration plans. Use of the report by the NRC would not occur until after it has been incorpoarted in the SRP.

  3. Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells.

    PubMed

    Ried, K; Finnis, M; Hobson, L; Mangelsdorf, M; Dayan, S; Nancarrow, J K; Woollatt, E; Kremmidiotis, G; Gardner, A; Venter, D; Baker, E; Richards, R I

    2000-07-01

    Fluorescence in situ hybridization of a tile path of DNA subclones has previously enabled the cyto-genetic definition of the minimal DNA sequence which spans the FRA16D common chromosomal fragile site, located at 16q23.2. Homozygous deletion of the FRA16D locus has been reported in adenocarcinomas of stomach, colon, lung and ovary. We have sequenced the 270 kb containing the FRA16D fragile site and the minimal homozygously deleted region in tumour cells. This sequence enabled localization of some of the tumour cell breakpoints to regions which contain AT-rich secondary structures similar to those associated with the FRA10B and FRA16B rare fragile sites. The FRA16D DNA sequence also led to the identification of an alternatively spliced gene, named FOR (fragile site FRA16D oxidoreductase), exons of which span both the fragile site and the minimal region of homozygous deletion. In addition, the complete DNA sequence of the FRA16D-containing FOR intron reveals no evidence of additional authentic transcripts. Alternatively spliced FOR transcripts (FOR I, FOR II and FOR III) encode proteins which share N-terminal WW domains and differ at their C-terminus, with FOR III having a truncated oxidoreductase domain. FRA16D-associated deletions selectively affect the FOR gene transcripts. Three out of five previously mapped translocation breakpoints in multiple myeloma are also located within the FOR gene. FOR is therefore the principle genetic target for DNA instability at 16q23.2 and perturbation of FOR function is likely to contribute to the biological consequences of DNA instability at FRA16D in cancer cells. PMID:10861292

  4. A Systems Approach to College Administration and Planning: A Descriptive Comparison of Selected Models, Programs, and Services. Suitable for Use in Small Colleges.

    ERIC Educational Resources Information Center

    Shoemaker, William A.

    A systems approach to college administration and planning is probably the most valuable tool available for coping with the complex problems facing institutions of higher education today. A system is defined as a set of interrelated elements, units, or subsystems that work together toward a common goal. If a college functions as a system, the…

  5. Trend Analysis of Administrative Documents Pertinent to the Community Alternatives and Institutional Reform Planning Grant Program. A Report to the U. S. Department of Health, Education and Welfare.

    ERIC Educational Resources Information Center

    Braddock, David L.; Sosowsky, Larry

    To identify trends in institutional reform and deinstitutionalization of the developmentally disabled, 34 administrative documents emanating from a federally funded planning grant program were examined. Documents were gathered in response to a survey letter to state Developmental Disabilities Councils, and fact sheets summarizing the documents…

  6. Collaboration and Conflict: Insights regarding Reducing Barriers to Participation through a Survey Study of Parents and School Administrators during Special Education Planning

    ERIC Educational Resources Information Center

    Tucker, Vanessa E.

    2009-01-01

    Parents and school administrators are both stakeholders in the IEP (Individualized Education Plan) process. While the inclusion of parents in the process as full members is mandated by IDEA 2004 there remains a growing problem of conflict within this process. Research has reviewed the process of conflict during the IEP meeting and other…

  7. Transmission of the fra(X) haplotype from three nonpenetrant brothers to their affected grandsons.

    PubMed

    Kirkilionis, A J; Chudley, A E; Greenberg, C R; Yan, D L; McGillivray, B; Hamerton, J L

    1992-06-01

    We report on a family showing transmission of the fra(X) gene by 3 nonpenetrant, fra(X) negative, normally intelligent, full and half-brothers to their affected grandsons. The mothers of the affected boys are obligate carriers, fra(X) negative, and of normal intelligence. This family illustrates the "Sherman Paradox" and is compatible with the predictions of the Laird X-inactivation imprinting model. In addition, molecular and/or cytogenetic studies have enabled at-risk relatives to learn more about their carrier fra(X) status and have allowed for more accurate genetic counselling. PMID:1605253

  8. Presence of hydroxyl in the Fra Mauro region

    NASA Astrophysics Data System (ADS)

    Berezhnoy, Alexey; Wöhler, Christian; Sinitsyn, Mikhail; Grumpe, Arne; Feoktistova, Ekaterina; Shevchenko, Vladislav

    Lunar pyroclastic deposits (LPDs) are known to consist of volcanic material (basalt and glass) ejected by eruptions [1]. In the southern part of the crater Fra Mauro, a localised LPD is associated with Rima Parry V [2]. In [3], a suppressed neutron flux is described for the Fra Mauro region based on measurements of the Lunar Exploration Neutron Detector (LEND) [4], interpreted as an indicator of hydroxyl (OH). In this study we compare these measurements with NIR hyperspectral data acquired by the Moon Mineralogy Mapper (M(3) ) [5] instrument. The suppression factor of the neutron flux is defined according to delta = (N_ref-N_ex)/N_ref [6,7] with N_ex as the average count rate of the omnidirectional sensor (SETN) [8] of LEND for the region under study (here: the Fra Mauro region) and N_ref as the average count rate for a reference area (here: immediately west of Fra Mauro). For Fra Mauro crater, a suppression factor of 2.4% with a standard error of 0.41% was found. The epithermal neutron flux can be assumed to be inversely proportional to the hydrogen content. Hence, the measured positive suppression factor indicates a positive anomaly of the hydrogen content at up to 1 m depth. Under the approximative assumption of a proportional relation between the suppression factor delta and the hydrogen content, the observation in [7] of a suppression factor of 18% in the crater Cabeus associated with a homogeneous hydrogen content of about 500 ppm implies an enrichment in hydrogen by about 70 ppm for the Fra Mauro region. However, these values do not specifically refer to the small Fra Mauro LPD but to a larger area of about 150 km diameter. To identify the LPD-specific suppression factor, it would be necessary to acquire collimated neutron flux measurements. We have complemented the LEND-based measurements by the analysis of spectral reflectance data acquired by the M(3) instrument. The presence of OH in the surface material leads to an absorption band beyond 2700 nm

  9. 77 FR 64374 - Notification of Petition for Approval; Port Authority Trans-Hudson Product Safety Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... a Product Safety Plan (PSP). FRA assigned the petition Docket Number FRA-2012-0075. PATH is... maintenance costs. PATH asserts that the PSP demonstrates that Digicode has been designed in a highly safe... Train Control Systems. The PSP itself provides the detailed description of the Digicode track...

  10. A metabolic intermediate of the fructose-asparagine utilization pathway inhibits growth of a Salmonella fraB mutant

    PubMed Central

    Sabag-Daigle, Anice; Blunk, Henry M.; Sengupta, Anindita; Wu, Jikang; Bogard, Alexander J.; Ali, Mohamed M.; Stahl, Christopher; Wysocki, Vicki H.; Gopalan, Venkat; Behrman, Edward J.; Ahmer, Brian M. M.

    2016-01-01

    Insertions in the Salmonella enterica fra locus, which encodes the fructose-asparagine (F-Asn) utilization pathway, are highly attenuated in mouse models of inflammation (>1000-fold competitive index). Here, we report that F-Asn is bacteriostatic to a fraB mutant (IC50 19 μM), but not to the wild-type or a fra island deletion mutant. We hypothesized that the presence of FraD kinase and absence of FraB deglycase causes build-up of a toxic metabolite: 6-phosphofructose-aspartate (6-P-F-Asp). We used biochemical assays to assess FraB and FraD activities, and mass spectrometry to confirm that the fraB mutant accumulates 6-P-F-Asp. These results, together with our finding that mutants lacking fraD or the fra island are not attenuated in mice, suggest that the extreme attenuation of a fraB mutant stems from 6-P-F-Asp toxicity. Salmonella FraB is therefore an excellent drug target, a prospect strengthened by the absence of the fra locus in most of the gut microbiota. PMID:27403719

  11. A metabolic intermediate of the fructose-asparagine utilization pathway inhibits growth of a Salmonella fraB mutant.

    PubMed

    Sabag-Daigle, Anice; Blunk, Henry M; Sengupta, Anindita; Wu, Jikang; Bogard, Alexander J; Ali, Mohamed M; Stahl, Christopher; Wysocki, Vicki H; Gopalan, Venkat; Behrman, Edward J; Ahmer, Brian M M

    2016-01-01

    Insertions in the Salmonella enterica fra locus, which encodes the fructose-asparagine (F-Asn) utilization pathway, are highly attenuated in mouse models of inflammation (>1000-fold competitive index). Here, we report that F-Asn is bacteriostatic to a fraB mutant (IC50 19 μM), but not to the wild-type or a fra island deletion mutant. We hypothesized that the presence of FraD kinase and absence of FraB deglycase causes build-up of a toxic metabolite: 6-phosphofructose-aspartate (6-P-F-Asp). We used biochemical assays to assess FraB and FraD activities, and mass spectrometry to confirm that the fraB mutant accumulates 6-P-F-Asp. These results, together with our finding that mutants lacking fraD or the fra island are not attenuated in mice, suggest that the extreme attenuation of a fraB mutant stems from 6-P-F-Asp toxicity. Salmonella FraB is therefore an excellent drug target, a prospect strengthened by the absence of the fra locus in most of the gut microbiota. PMID:27403719

  12. 49 CFR Appendix C to Part 209 - FRA's Policy Statement Concerning Small Entities

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) explains FRA's communication and enforcement policies concerning small entities subject to the federal... hazardous materials shippers meeting the economic criteria established for Class III railroads in 49 CFR... enforcement actions against small businesses. Small Entity Communication Policy It is FRA's policy that...

  13. 49 CFR 219.206 - FRA access to breath test results.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false FRA access to breath test results. 219.206 Section 219.206 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.206 FRA access to breath test results. Documentation of breath test results must be made...

  14. 49 CFR 219.206 - FRA access to breath test results.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false FRA access to breath test results. 219.206 Section 219.206 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.206 FRA access to breath test results. Documentation of breath test results must be made...

  15. 49 CFR 219.206 - FRA access to breath test results.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false FRA access to breath test results. 219.206 Section 219.206 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.206 FRA access to breath test results. Documentation of breath test results must be made...

  16. 49 CFR 219.206 - FRA access to breath test results.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false FRA access to breath test results. 219.206 Section 219.206 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.206 FRA access to breath test results. Documentation of breath test results must be made...

  17. 49 CFR 219.206 - FRA access to breath test results.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false FRA access to breath test results. 219.206 Section 219.206 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.206 FRA access to breath test results. Documentation of breath test results must be made...

  18. News and views on EMT Fra-1 controls EMT in mammary epithelial cells

    PubMed Central

    Bakiri, Latifa; Wagner, Erwin F.

    2016-01-01

    Epithelial-to-mesenchymal transition (EMT), a process critical for breast cancer cell dissemination, engages the Fos-related antigen 1 (Fra-1) transcription factor. Molecular and cellular analyses revealed an evolutionary conservation of Fra-1 functions in EMT of mouse and human mammary cells, establishing a solid basis for preclinical studies in genetically engineered mouse models.

  19. Apollo 14 - Nature and origin of rock types in soil from the Fra Mauro formation.

    NASA Technical Reports Server (NTRS)

    Aitken, F. K.; Anderson, D. H.; Bass, M. N.; Brown, R. W.; Butler, P., Jr.; Heiken, G.; Jakes, P.; Reid, A. M.; Ridley, W. I.; Takeda, H.

    1971-01-01

    Compositions of glasses in the Apollo 14 soil correspond to four types of Fra Mauro basalts, to mare basalts and soils, and, in minor amounts, to gabbroic anorthosite and potash granite. The Fra Mauro basalts can be related by simple low pressure crystal-liquid fractionation that implies a parent composition like that of Apollo 14 sample 14310.

  20. Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration (Report and Appendix)

    SciTech Connect

    Eudy, L.; Chandler, K.

    2010-11-01

    This document describes the fuel cell transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's Federal Transit Administration (FTA). This document provides a description of the demonstration sites, funding sources, and data collection activities for fuel cell transit bus evaluations currently planned from FY10 through FY12.

  1. Work Stoppage Strategies. A Guide to Assist School Administrators to Develop Strike Management Plans. AASA Executive Handbook Series, Volume 6.

    ERIC Educational Resources Information Center

    American Association of School Administrators, Washington, DC.

    This handbook provides help and direction in minimizing the impact of a teacher strike on the local community. It is, in essence, a management plan to deal with work stoppages on as high a professional plane as possible. Modification must be made to meet local and state circumstances. Each school district must write a plan in line with its own…

  2. A Course into the '80s: Developing a Plan and a Planning Process at Cumberland County College. A Report to Cumberland County College Planning Committee, Administration, and Board of Trustees.

    ERIC Educational Resources Information Center

    Martorana, S. V.; And Others

    Cumberland County College with a team of consultants developed a long-range plan along with a continuing planning process to assure the college's continued effectiveness. Aspects of the planning process include: review of available reports relevant to the college's long-range planning; identification of preliminary goals and objectives; assessment…

  3. Administrative IT

    ERIC Educational Resources Information Center

    Grayson, Katherine, Ed.

    2006-01-01

    When it comes to Administrative IT solutions and processes, best practices range across the spectrum. Enterprise resource planning (ERP), student information systems (SIS), and tech support are prominent and continuing areas of focus. But widespread change can also be accomplished via the implementation of campuswide document imaging and sharing,…

  4. Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.

    PubMed

    Bozec, Aline; Bakiri, Latifa; Jimenez, Maria; Schinke, Thorsten; Amling, Michael; Wagner, Erwin F

    2010-09-20

    The activator protein-1 (AP-1) transcription factor complex, in particular the Fos proteins, is an important regulator of bone homeostasis. Fra-2 (Fosl2), a Fos-related protein of the AP-1 family, is expressed in bone cells, and newborn mice lacking Fra-2 exhibit defects in chondrocytes and osteoclasts. Here we show that Fra-2-deficient osteoblasts display a differentiation defect both in vivo and in vitro. Moreover, Fra-2-overexpressing mice are osteosclerotic because of increased differentiation of osteoblasts, which appears to be cell autonomous. Importantly, the osteoblast-specific osteocalcin (Oc) gene and collagen1α2 (col1α2) are transcriptional targets of Fra-2 in both murine and human bone cells. In addition, Fra-2, Oc, and col1 are expressed in stromal cells of human chondroblastic and osteoblastic osteosarcomas (Os's) as well as during osteoblast differentiation of human Os cell lines. These findings reveal a novel function of Fra-2/AP-1 as a positive regulator of bone and matrix formation in mice and humans. PMID:20837772

  5. 77 FR 74183 - Farm Credit Administration Board Action To Approve a Plan of Voluntary Liquidation for, and To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... the Charter of, the Farm Credit Finance Corporation of Puerto Rico AGENCY: Farm Credit Administration... voluntary liquidation of the Farm Credit Finance Corporation of Puerto Rico (FCFCPR) without the appointment... Credit Finance Corporation of Puerto Rico under FCA's regulation Sec. 627.2795--Voluntary Liquidation...

  6. 76 FR 38267 - The Federal Motor Carrier Safety Administration's 2011-2016 Strategic Plan: Raising the Safety Bar

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... was held on September 8, 2010 (75 FR 53015, August 30, 2010). The new draft strategic plan, The... the comment, if submitted on behalf of an association, business, labor union, etc.). You may review... FR 3316) at http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . FOR FURTHER INFORMATION CONTACT:...

  7. 23 CFR 420.121 - What other requirements apply to the administration of FHWA planning and research funds?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... research funds by the State DOTs must be in accordance with 49 CFR 18.32(b). Local government subrecipients... research funds by the State DOTs must be in accordance with 49 CFR 18.36(a) and (i) and, if applicable, 18... DOTs and their subrecipients with FHWA planning and research funds must be in accordance with 49 CFR...

  8. Reducing inpatient falls in a 100% single room elderly care environment: evaluation of the impact of a systematic nurse training programme on falls risk assessment (FRA).

    PubMed

    Singh, Inderpal; Okeke, Justin

    2016-01-01

    Inpatient falls (IF) are the most commonly reported safety incidents. The high rate of inpatient falls was reported in a newly built hospital, within Aneurin Bevan University Health Board, Wales (UK). The aim of the project is to reduce the incidence of IF and associated adverse clinical outcomes in a hospital with 100% single rooms. The key mechanism for improvement was education and training of nursing staff around falls risk factors. A Plan-Do-Study-Act methodology was used and a geriatrician-led, systematic nurse training programme on the understanding and correct use of existing multifactorial falls risk assessment (FRA) tool was implemented in April 2013. Pre-training baseline data revealed inadequate falls assessment and low completion rates of the FRA tool. Subsequent, post-training data showed improvement in compliance with all aspects of FRA. Concurrent with nurse training, the actual falls incidence/1000 patient-bed-days fell significantly from the baseline of 18.19±3.46 (Nov 2011-March 2013) to 13.36±2.89 (p<0.001) over next 12 months (April 2013-March 2014) and remained low (mean falls 12.81±2.85) until November 2015. Improved clinical outcomes have been observed in terms of a reduction of length of stay and new care home placements, making total annualised savings of £642,055. PMID:27559476

  9. Reducing inpatient falls in a 100% single room elderly care environment: evaluation of the impact of a systematic nurse training programme on falls risk assessment (FRA)

    PubMed Central

    Singh, Inderpal; Okeke, Justin

    2016-01-01

    Inpatient falls (IF) are the most commonly reported safety incidents. The high rate of inpatient falls was reported in a newly built hospital, within Aneurin Bevan University Health Board, Wales (UK). The aim of the project is to reduce the incidence of IF and associated adverse clinical outcomes in a hospital with 100% single rooms. The key mechanism for improvement was education and training of nursing staff around falls risk factors. A Plan-Do-Study-Act methodology was used and a geriatrician-led, systematic nurse training programme on the understanding and correct use of existing multifactorial falls risk assessment (FRA) tool was implemented in April 2013. Pre-training baseline data revealed inadequate falls assessment and low completion rates of the FRA tool. Subsequent, post-training data showed improvement in compliance with all aspects of FRA. Concurrent with nurse training, the actual falls incidence/1000 patient-bed-days fell significantly from the baseline of 18.19±3.46 (Nov 2011-March 2013) to 13.36±2.89 (p<0.001) over next 12 months (April 2013-March 2014) and remained low (mean falls 12.81±2.85) until November 2015. Improved clinical outcomes have been observed in terms of a reduction of length of stay and new care home placements, making total annualised savings of £642,055. PMID:27559476

  10. 75 FR 8785 - Agency Request for Emergency Processing of Collection of Information Associated With FRA's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... ICR, with applicable supporting documentation, may be obtained by calling FRA's Clearance Officers, Mr... toll-free. A copy of this ICR may also be obtained electronically by contacting Mr. Brogan at...

  11. Administrative simplification: adoption of operating rules for eligibility for a health plan and health care claim status transactions. Interim final rule with comment period.

    PubMed

    2011-07-01

    Section 1104 of the Administrative Simplification provisions of the Patient Protection and Affordable Care Act (hereafter referred to as the Affordable Care Act) establishes new requirements for administrative transactions that will improve the utility of the existing HIPAA transactions and reduce administrative costs. Specifically, in section 1104(b)(2) of the Affordable Care Act, Congress required the adoption of operating rules for the health care industry and directed the Secretary of Health and Human Services to "adopt a single set of operating rules for each transaction * * * with the goal of creating as much uniformity in the implementation of the electronic standards as possible." This interim final rule with comment period adopts operating rules for two Health Insurance Portability and Accountability Act of 1996 (HIPAA) transactions: eligibility for a health plan and health care claim status. This rule also defines the term "operating rules" and explains the role of operating rules in relation to the adopted transaction standards. In general, transaction standards adopted under HIPAA enable electronic data interchange through a common interchange structure, thus minimizing the industry's reliance on multiple formats. Operating rules, in turn, attempt to define the rights and responsibilities of all parties, security requirements, transmission formats, response times, liabilities, exception processing, error resolution and more, in order to facilitate successful interoperability between data systems of different entities. PMID:21739765

  12. SAVEnergy Action Plan: National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northwest Fisheries Science Center, Seattle, Washington

    SciTech Connect

    Parker, S.A.; Wahlstrom, R.R.; Richman, E.E.; Sandusky, W.F. III; Dittmer, A.L.

    1995-05-01

    The Pacific Northwest Laboratory (PNL) conducted a SAVEnergy Audit of the National Oceanic and Atmospheric Administration`s (NOAA) National Marine Fisheries Service, Northwest Fisheries Science Center in Seattle, Washington. The objectives of this study were to evaluate the performance of all energy-consuming equipment in the facility, to estimate energy consumption and demand by end-use and to recommend energy conservation measures (ECMs) and water conservation measures (WCMs) to reduce costs . This section describes the facility and the systems encountered during the visit by the audit team. It also presents a summary of energy conservation measures. Section 2 shows energy consumption and costs for electricity, natural gas and water. A breakdown of energy consumed by end-use is also presented. Recommended energy conservation measures are presented in Section 3. Section 4 contains a discussion of operations and maintenance issues and other energy measures that can be implemented on a replace-on-failure basis rather than replacing immediately. Appendix A contains a three-year history of consumption, demand and cost for electric, natural gas and water utilities. Appendix B contains information on local weather data correlated to utility billing periods. A brief summary on Federal life-cycle costing is located in Appendix C along with the life-cycle cost analyses summaries for the energy and water conservation measures detailed in this report. Information on the rebate program sponsored by Seattle City Light, the electric utility, is located in Appendix D. Sample information for water-efficient equipment is located in Appendix E. Appendix F contains submittal forms to the Federal Energy Efficiency Fund for the energy conservation measures recommended in Section 3 of this report. A glossary of terms and abbreviations used in this report is located in Appendix G.

  13. Succession planning for the future through an academic-practice partnership: a nursing administration master's program for emerging nurse leaders.

    PubMed

    Sherman, Rose; Dyess, Susan; Hannah, Ed; Prestia, Angela

    2013-01-01

    A global nursing leadership shortage is projected by the end of this decade. There is an urgent need to begin developing emerging nurse leaders now. This article describes the work of an academic-practice partnership collaborative of nurse leaders. The goal of the partnership is to develop and promote an innovative enhanced nursing administration master's program targeted to young emerging nurse leaders, who have not yet moved into formal leadership roles. An action research design is being used in program development and evaluation. Qualities needed by emerging leaders identified through research included a need to be politically astute, competency with business skills required of nurse leaders today, comfort with ambiguity, use of a caring approach, and leadership from a posture of innovation. The current curriculum was revised to include clinical immersion with a nurse leader from the first semester in the program, a change from all online to online/hybrid courses, innovative assignments, and a strong mentorship component. Eighteen young emerging nurse leaders began the program in January 2012. Early outcomes are positive. The emerging nurse leaders may be uniquely positioned, given the right skills sets, to be nurse leaders in the new age. PMID:23222750

  14. Histidine 103 in Fra2 Is an Iron-Sulfur Cluster Ligand in the [2Fe-2S] Fra2-Grx3 Complex and Is Required for in Vivo Iron Signaling in Yeast*

    PubMed Central

    Li, Haoran; Mapolelo, Daphne T.; Dingra, Nin N.; Keller, Greg; Riggs-Gelasco, Pamela J.; Winge, Dennis R.; Johnson, Michael K.; Outten, Caryn E.

    2011-01-01

    The BolA homologue Fra2 and the cytosolic monothiol glutaredoxins Grx3 and Grx4 together play a key role in regulating iron homeostasis in Saccharomyces cerevisiae. Genetic studies indicate that Grx3/4 and Fra2 regulate activity of the iron-responsive transcription factors Aft1 and Aft2 in response to mitochondrial Fe-S cluster biosynthesis. We have previously shown that Fra2 and Grx3/4 form a [2Fe-2S]2+-bridged heterodimeric complex with iron ligands provided by the active site cysteine of Grx3/4, glutathione, and a histidine residue. To further characterize this unusual Fe-S-binding complex, site-directed mutagenesis was used to identify specific residues in Fra2 that influence Fe-S cluster binding and regulation of Aft1 activity in vivo. Here, we present spectroscopic evidence that His-103 in Fra2 is an Fe-S cluster ligand in the Fra2-Grx3 complex. Replacement of this residue does not abolish Fe-S cluster binding, but it does lead to a change in cluster coordination and destabilization of the [2Fe-2S] cluster. In vivo genetic studies further confirm that Fra2 His-103 is critical for control of Aft1 activity in response to the cellular iron status. Using CD spectroscopy, we find that ∼1 mol eq of apo-Fra2 binds tightly to the [2Fe-2S] Grx3 homodimer to form the [2Fe-2S] Fra2-Grx3 heterodimer, suggesting a mechanism for formation of the [2Fe-2S] Fra2-Grx3 heterodimer in vivo. Taken together, these results demonstrate that the histidine coordination and stability of the [2Fe-2S] cluster in the Fra2-Grx3 complex are essential for iron regulation in yeast. PMID:20978135

  15. FRaC: a feature-modeling approach for semi-supervised and unsupervised anomaly detection

    PubMed Central

    Brodley, Carla; Slonim, Donna

    2011-01-01

    Anomaly detection involves identifying rare data instances (anomalies) that come from a different class or distribution than the majority (which are simply called “normal” instances). Given a training set of only normal data, the semi-supervised anomaly detection task is to identify anomalies in the future. Good solutions to this task have applications in fraud and intrusion detection. The unsupervised anomaly detection task is different: Given unlabeled, mostly-normal data, identify the anomalies among them. Many real-world machine learning tasks, including many fraud and intrusion detection tasks, are unsupervised because it is impractical (or impossible) to verify all of the training data. We recently presented FRaC, a new approach for semi-supervised anomaly detection. FRaC is based on using normal instances to build an ensemble of feature models, and then identifying instances that disagree with those models as anomalous. In this paper, we investigate the behavior of FRaC experimentally and explain why FRaC is so successful. We also show that FRaC is a superior approach for the unsupervised as well as the semi-supervised anomaly detection task, compared to well-known state-of-the-art anomaly detection methods, LOF and one-class support vector machines, and to an existing feature-modeling approach. PMID:22639542

  16. Fra(10)(q25): the BrdU effect is substitution-dependent.

    PubMed Central

    Gollin, S M; Holmquist, G P; Ledbetter, D H

    1985-01-01

    Expression in the majority of fra(10)(q25) cases is either induced or enhanced by the presence of bromodeoxyuridine (BrdU) in the culture medium. BrdU is known to exert its effects on cells via two primary mechanisms: substitution-dependent and concentration-dependent. BrdU incorporation into DNA and BrdU concentration in the culture medium can be resolved as independent variables. The results of such experiments indicate that at three fixed levels of BrdU substitution, 100-fold variation of BrdU concentration had little or no effect on fra(10)(q25) expression. At a fixed BrdU concentration, the level of fra(10)(q25) expression rises as a function of increased BrdU substitution, approaching 100% expression at 100% substitution. Thus, BrdU induction or enhancement of fra(10)(q25) expression is clearly substitution-dependent. Iododeoxyuridine, another halogenated pyrimidine, has a similar effect. The critical time of incorporation is between 8 and 9 hrs before mitosis. After this time, removal of BrdU (and fluorodeoxyuridine [FdU]) from the culture medium followed by addition of deoxythymidine does not reverse the BrdU effect on fra(10)(q25) expression. PMID:3976659

  17. UCSD/FRA non-contact ultrasonic guided-wave system for rail inspection: an update

    NASA Astrophysics Data System (ADS)

    Coccia, Stefano; Phillips, Robert; Nucera, Claudio; Bartoli, Ivan; Salamone, Salvatore; Lanza di Scalea, Francesco; Fateh, Mahmood; Carr, Gary

    2011-04-01

    The University of California at San Diego (UCSD), under a Federal Railroad Administration (FRA) Office of Research and Development (R&D) grant, is developing a system for high-speed and non-contact rail defect detection. A prototype has been designed and field tested with the support of Volpe National Transportation Systems Center and ENSCO, Inc. The goal of this project is to develop a rail defect detection system that provides (a) better defect detection reliability (including internal transverse head defects under shelling and vertical split head defects), and (b) higher inspection speed than achievable by current rail inspection systems. This effort is also in direct response to Safety Recommendations issued by the National Transportation Safety Board (NTSB) following the disastrous train derailments at Superior, WI in 1992 and Oneida, NY in 2007 among others. The UCSD prototype uses non-contact ultrasonic probing of the rail head (laser and air-coupled), ultrasonic guided waves, and a proprietary real-time statistical analysis algorithm that maximizes the sensitivity to defects while minimizing false positives. The current design allows potential inspection speeds up to 40 mph, although all field tests have been conducted up to 15 mph so far. This paper summarizes (a) the latest technology development test conducted at the rail defect farm of Herzog, Inc. in St Joseph, MO in June 2010, and (b) the completion of the new Rail Defect Farm facility at the UCSD Camp Elliott Field Station with partial in-kind donations from the Burlington Northern Santa Fe (BNSF) Railway.

  18. Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron.

    PubMed Central

    Bergers, G; Graninger, P; Braselmann, S; Wrighton, C; Busslinger, M

    1995-01-01

    Constitutive expression of c-Fos, FosB, Fra-1, or c-Jun in rat fibroblasts leads to up-regulation of the immediate-early gene fra-1. Using the posttranslational FosER induction system, we demonstrate that this AP-1-dependent stimulation of fra-1 expression is rapid, depends on a functional DNA-binding domain of FosER, and is a general phenomenon observed in different cell types. In vitro mutagenesis and functional analysis of the rat fra-1 gene in stably transfected Rat-1A-FosER fibroblasts indicated that basal and AP-1-regulated expression of the fra-1 gene depends on regulatory sequences in the first intron which comprise a consensus AP-1 site and two AP-1-like elements. We have also investigated the transactivating and transforming properties of the Fra-1 protein to address the significance of fra-1 up-regulation. The entire Fra-1 protein fused to the DNA-binding domain of Ga14 is shown to lack any transactivation function, and yet it possesses oncogenic potential, as overexpression of Fra-1 in established rat fibroblasts results in anchorage-independent growth in vitro and tumor development in athymic mice, fra-1 is therefore not only induced by members of the Fos family, but its gene product may also contribute to cellular transformation by these proteins. Together, these data identify fra-1 as a unique member of the fos gene family which is under positive control by AP-1 activity. PMID:7791782

  19. Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.

    PubMed

    Bakiri, Latifa; Takada, Yasunari; Radolf, Martin; Eferl, Robert; Yaniv, Moshe; Wagner, Erwin F; Matsuo, Koichi

    2007-04-01

    Bone resorbing osteoclasts are specialized macrophages that cannot differentiate in the absence of c-Fos, a member of the dimeric transcription factor AP-1 (activator protein-1). However, osteoclast differentiation in the absence of c-Fos can be rescued in vitro and in vivo by Fra1, a Fos-like protein and transcriptional target of c-Fos. To enable AP-1 proteins binding to DNA, c-Fos or Fra1 must heterodimerize with a partner such as c-Jun, JunB and JunD. In this study, we investigated the dimerization partners of c-Fos and Fra1 required for osteoclast differentiation using synthetic "single-chain" AP-1 dimers in which c-Fos or Fra1 is tethered via a linker to Jun proteins. When c-Fos was analyzed in combination with any Jun protein, including a c-Jun mutant lacking major phosphorylation sites for c-Jun amino-terminal kinase (JNK), osteoclasts were efficiently formed from c-Fos-deficient hematopoietic precursors. However, Fra1 in combination with any Jun protein could not rescue osteoclastogenesis. The ability to rescue was compared to transcriptional activity measured in transient transfection assays using promoters driven by consensus AP-1 sites or a composite AP-1/NFAT binding site. These data show that a single Jun/c-Fos dimer is sufficient for osteoclast differentiation, likely due to its transactivation ability for a broader range of promoters, in particular consensus AP-1 sites. We propose that Fra1 together with a dimerization partner different from Jun proteins can rescue osteoclast differentiation in c-Fos-deficient precursors. PMID:17189721

  20. 49 CFR 229.207 - New locomotive crashworthiness design standards and changes to existing FRA-approved locomotive...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-approved locomotive crashworthiness design standards. (a) General. The following procedures govern... approval of a locomotive crashworthiness design standard must be titled “Petition for FRA Approval of a New... petition for approval of a substantive change to an FRA-approved locomotive crashworthiness design...

  1. The F8H Glycosyltransferase is a Functional Paralog of FRA8 Involved in Glucuronoxylan Biosynthesis in Arabidopsis

    EPA Science Inventory

    The FRAGILE FIBER8 gene was previously shown to be required for the biosynthesis of the reducing end tetrasaccharide sequence of glucuronoxylan (GX) in Arabidopsis thaliana. Here, we demonstrate that F8H, a close homolog of FRA8, is a functional ortholog of FRA8 involved in GX bi...

  2. 49 CFR 229.207 - New locomotive crashworthiness design standards and changes to existing FRA-approved locomotive...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false New locomotive crashworthiness design standards... Design Requirements § 229.207 New locomotive crashworthiness design standards and changes to existing FRA... consideration and action upon requests for FRA approval of new locomotive crashworthiness design standards...

  3. Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis

    PubMed Central

    2013-01-01

    Background The Fra-1/AP-1 transcription factor regulates the expression of genes controlling various processes including migration, invasion, and survival as well as extracellular remodeling. We recently demonstrated that loss of Fra-1 leads to exacerbated bleomycin-induced pulmonary fibrosis, accompanied by enhanced expression of various inflammatory and fibrotic genes. To better understand the molecular mechanisms by which Fra-1 confers protection during bleomycin-induced lung injury, genome-wide mRNA expression profiling was performed. Results We found that Fra-1 regulates gene expression programs that include: 1) several cytokines and chemokines involved in inflammation, 2) several genes involved in the extracellular remodeling and cell adhesion, and 3) several genes involved in programmed cell death. Conclusion Loss of Fra-1 leads to the enhanced expression of genes regulating inflammation and immune responses and decreased the expression of genes involved in apoptosis, suggesting that this transcription factor distinctly modulates early pro-fibrotic cellular responses. PMID:23758685

  4. Uniparental disomy (UPD) for fra(X) in a 47,XXY male

    SciTech Connect

    Torfs, C.P.; Christianson, R.E.; Amos, J.A.; Huang, X.L.; Kang, X.Z.

    1994-09-01

    We report a 4-year-old hyperactive, mentally retarded male with 47,XXY and UPD for fra(X). Speech and motor delay were first noted at age 15 months. He has no dysmorphic features, normal ears, hyperextensible joints, small testes, and no history of seizures. His mother has prominent lowest ears, a long midface, anteverted nostrils, hyperextensible joints, malocclusion, and had learning problems in school. Routine chromosome analysis revealed the proband to be 47,XXY. Parental chromosomes were normal in number. The proband was fra(X) positive [30/160 cells, 18%]. No cells had two expressed fra(X)s; however, this may be a function of the low level of expression and the number of cells scored. Maternal cells were also fra(X) positive [19/205, 9.2%]. Southern analysis demonstrated the mother to be heterozygous for a methylated, full mutation (>220 repeats); her normal FMR-1 gene was disproportionately unmethylated. The proband had two fully expanded and methylated FMR-1 genes, one the same size as the maternal gene and the other >620 repeats. RFLP analysis revealed a maternal meiotic II error, the result of which was UPD of the X chromosome.

  5. 49 CFR Appendix C to Part 209 - FRA's Policy Statement Concerning Small Entities

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... hazardous materials shippers meeting the economic criteria established for Class III railroads in 49 CFR... described in Appendix A to 49 CFR part 209, it is FRA's policy to consider a variety of factors in... provide oral and written responses to questions raised by small entities concerning the plain meaning...

  6. 49 CFR Appendix C to Part 209 - FRA's Policy Statement Concerning Small Entities

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... hazardous materials shippers meeting the economic criteria established for Class III railroads in 49 CFR... described in Appendix A to 49 CFR part 209, it is FRA's policy to consider a variety of factors in... provide oral and written responses to questions raised by small entities concerning the plain meaning...

  7. 75 FR 34213 - Solicitation of Applications and Notice of Funding Availability for the FRA Railroad System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... 13, 2010 (75 FR 27112), the FRA sought applications from interested and responsible parties for two grants: to conduct a Locomotive Biofuel Study, and to conduct a Study of the Use of Bio-based... consult the notice published on May 13, 2010 in the Federal Register (75 FR 27112) for additional...

  8. 75 FR 27112 - Solicitation of Applications and Notice of Funding Availability for the FRA Railroad System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ...Under this Notice, the FRA is soliciting applications from interested and responsible parties for two grants: (1) To conduct a Locomotive Biofuel Study, and (2) to conduct a Study of the Use of Bio- based Technologies (Lubricants) that can be used in locomotives, rolling stock and other rail...

  9. 75 FR 59322 - Notice of Availability of Answers to Frequently Asked Questions Regarding Buy America & FRA's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ... Buy America & FRA's High-Speed Intercity Passenger Rail Program AGENCY: Federal Railroad...'s High Speed Intercity ] Passenger Rail Program. The Answers to Frequently Asked Questions can be... to support intercity passenger rail service (Sec. 301), high-speed corridor development (Sec....

  10. 49 CFR Appendix C to Part 229 - FRA Locomotive Standards-Code of Defects

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FR 21121, Mar. 31, 1980, as part of the original document, is not carried in the CFR. ... 49 Transportation 4 2010-10-01 2010-10-01 false FRA Locomotive Standards-Code of Defects C Appendix C to Part 229 Transportation Other Regulations Relating to Transportation (Continued)...

  11. 49 CFR Appendix C to Part 229 - FRA Locomotive Standards-Code of Defects

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FR 21121, Mar. 31, 1980, as part of the original document, is not carried in the CFR. ... 49 Transportation 4 2013-10-01 2013-10-01 false FRA Locomotive Standards-Code of Defects C Appendix C to Part 229 Transportation Other Regulations Relating to Transportation (Continued)...

  12. 49 CFR Appendix C to Part 229 - FRA Locomotive Standards-Code of Defects

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FR 21121, Mar. 31, 1980, as part of the original document, is not carried in the CFR. ... 49 Transportation 4 2014-10-01 2014-10-01 false FRA Locomotive Standards-Code of Defects C Appendix C to Part 229 Transportation Other Regulations Relating to Transportation (Continued)...

  13. 15 CFR 990.61 - Administrative record.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... constructive notice of the Draft Restoration Plan and the opportunity to comment on the plan; (2) Do not... regarding the Final Restoration Plan. (b) Opening an administrative record for restoration implementation... Final Restoration Plan....

  14. 15 CFR 990.61 - Administrative record.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... constructive notice of the Draft Restoration Plan and the opportunity to comment on the plan; (2) Do not... regarding the Final Restoration Plan. (b) Opening an administrative record for restoration implementation... Final Restoration Plan....

  15. 15 CFR 990.61 - Administrative record.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... constructive notice of the Draft Restoration Plan and the opportunity to comment on the plan; (2) Do not... regarding the Final Restoration Plan. (b) Opening an administrative record for restoration implementation... Final Restoration Plan....

  16. 15 CFR 990.61 - Administrative record.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... constructive notice of the Draft Restoration Plan and the opportunity to comment on the plan; (2) Do not... regarding the Final Restoration Plan. (b) Opening an administrative record for restoration implementation... Final Restoration Plan....

  17. Targeting "Plan Colombia": A Critical Analysis of Ideological and Political Visual Narratives by the Beehive Collective and the Drug Enforcement Administration Museum

    ERIC Educational Resources Information Center

    Erler, Carolyn

    2008-01-01

    This article compares the Beehive Collective's "Plan Colombia" to a museum exhibition representing the official U.S. position on Plan Colombia. Through a dialectical (Kellner & Share, 2007; Greene, 1988) reading of "Plan Colombia" and "Target America," I examine how each uses visual narrative to promote a particular reading of Plan Colombia.…

  18. Planning and Conducting a Program of Instruction in Vocational Agriculture for Young Farmers. Suggestions for Teachers and School Administrators in Developing Educational Programs for Out-of-School Young Farmers. (Revised.)

    ERIC Educational Resources Information Center

    Olsen, Les; And Others

    Designed to help vocational educators, including both teachers and administrators, in secondary and postsecondary institutions to plan, finance, and conduct instructional programs for young farmers and young agribusiness personnel, this manual focuses upon the need and importance of such adult vocational education and provides specific suggestions…

  19. Educational Administration and Multilevel Plan Implementation: Experiences from Developing Countries. Contributions to IIEP Seminars Held in November 1979, November 1980 and to an IIEP Workshop Held in December 1980.

    ERIC Educational Resources Information Center

    Malpica, Carlos; Rassekh, Shapour

    Eight papers, each presented at one of three conferences sponsored by the International Institute for Educational Planning (IIEP), are published together in this collection. It provides an overview of the current interest in developing nations in the role of administration in educational development, particularly as that role involves the…

  20. FRA2A is a CGG repeat expansion associated with silencing of AFF3.

    PubMed

    Metsu, Sofie; Rooms, Liesbeth; Rainger, Jacqueline; Taylor, Martin S; Bengani, Hemant; Wilson, David I; Chilamakuri, Chandra Sekhar Reddy; Morrison, Harris; Vandeweyer, Geert; Reyniers, Edwin; Douglas, Evelyn; Thompson, Geoffrey; Haan, Eric; Gecz, Jozef; Fitzpatrick, David R; Kooy, R Frank

    2014-04-01

    Folate-sensitive fragile sites (FSFS) are a rare cytogenetically visible subset of dynamic mutations. Of the eight molecularly characterized FSFS, four are associated with intellectual disability (ID). Cytogenetic expression results from CGG tri-nucleotide-repeat expansion mutation associated with local CpG hypermethylation and transcriptional silencing. The best studied is the FRAXA site in the FMR1 gene, where large expansions cause fragile X syndrome, the most common inherited ID syndrome. Here we studied three families with FRA2A expression at 2q11 associated with a wide spectrum of neurodevelopmental phenotypes. We identified a polymorphic CGG repeat in a conserved, brain-active alternative promoter of the AFF3 gene, an autosomal homolog of the X-linked AFF2/FMR2 gene: Expansion of the AFF2 CGG repeat causes FRAXE ID. We found that FRA2A-expressing individuals have mosaic expansions of the AFF3 CGG repeat in the range of several hundred repeat units. Moreover, bisulfite sequencing and pyrosequencing both suggest AFF3 promoter hypermethylation. cSNP-analysis demonstrates monoallelic expression of the AFF3 gene in FRA2A carriers thus predicting that FRA2A expression results in functional haploinsufficiency for AFF3 at least in a subset of tissues. By whole-mount in situ hybridization the mouse AFF3 ortholog shows strong regional expression in the developing brain, somites and limb buds in 9.5-12.5dpc mouse embryos. Our data suggest that there may be an association between FRA2A and a delay in the acquisition of motor and language skills in the families studied here. However, additional cases are required to firmly establish a causal relationship. PMID:24763282

  1. FRA2A Is a CGG Repeat Expansion Associated with Silencing of AFF3

    PubMed Central

    Metsu, Sofie; Rooms, Liesbeth; Rainger, Jacqueline; Taylor, Martin S.; Bengani, Hemant; Wilson, David I.; Chilamakuri, Chandra Sekhar Reddy; Morrison, Harris; Vandeweyer, Geert; Reyniers, Edwin; Douglas, Evelyn; Thompson, Geoffrey; Haan, Eric; Gecz, Jozef; FitzPatrick, David R.; Kooy, R. Frank

    2014-01-01

    Folate-sensitive fragile sites (FSFS) are a rare cytogenetically visible subset of dynamic mutations. Of the eight molecularly characterized FSFS, four are associated with intellectual disability (ID). Cytogenetic expression results from CGG tri-nucleotide-repeat expansion mutation associated with local CpG hypermethylation and transcriptional silencing. The best studied is the FRAXA site in the FMR1 gene, where large expansions cause fragile X syndrome, the most common inherited ID syndrome. Here we studied three families with FRA2A expression at 2q11 associated with a wide spectrum of neurodevelopmental phenotypes. We identified a polymorphic CGG repeat in a conserved, brain-active alternative promoter of the AFF3 gene, an autosomal homolog of the X-linked AFF2/FMR2 gene: Expansion of the AFF2 CGG repeat causes FRAXE ID. We found that FRA2A-expressing individuals have mosaic expansions of the AFF3 CGG repeat in the range of several hundred repeat units. Moreover, bisulfite sequencing and pyrosequencing both suggest AFF3 promoter hypermethylation. cSNP-analysis demonstrates monoallelic expression of the AFF3 gene in FRA2A carriers thus predicting that FRA2A expression results in functional haploinsufficiency for AFF3 at least in a subset of tissues. By whole-mount in situ hybridization the mouse AFF3 ortholog shows strong regional expression in the developing brain, somites and limb buds in 9.5–12.5dpc mouse embryos. Our data suggest that there may be an association between FRA2A and a delay in the acquisition of motor and language skills in the families studied here. However, additional cases are required to firmly establish a causal relationship. PMID:24763282

  2. Requirement of Fra proteins for communication channels between cells in the filamentous nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120.

    PubMed

    Omairi-Nasser, Amin; Mariscal, Vicente; Austin, Jotham R; Haselkorn, Robert

    2015-08-11

    The filamentous nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120 differentiates specialized cells, heterocysts, that fix atmospheric nitrogen and transfer the fixed nitrogen to adjacent vegetative cells. Reciprocally, vegetative cells transfer fixed carbon to heterocysts. Several routes have been described for metabolite exchange within the filament, one of which involves communicating channels that penetrate the septum between adjacent cells. Several fra gene mutants were isolated 25 y ago on the basis of their phenotypes: inability to fix nitrogen and fragmentation of filaments upon transfer from N+ to N- media. Cryopreservation combined with electron tomography were used to investigate the role of three fra gene products in channel formation. FraC and FraG are clearly involved in channel formation, whereas FraD has a minor part. Additionally, FraG was located close to the cytoplasmic membrane and in the heterocyst neck, using immunogold labeling with antibody raised to the N-terminal domain of the FraG protein. PMID:26216997

  3. Requirement of Fra proteins for communication channels between cells in the filamentous nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120

    PubMed Central

    Omairi-Nasser, Amin; Mariscal, Vicente; Austin, Jotham R.; Haselkorn, Robert

    2015-01-01

    The filamentous nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120 differentiates specialized cells, heterocysts, that fix atmospheric nitrogen and transfer the fixed nitrogen to adjacent vegetative cells. Reciprocally, vegetative cells transfer fixed carbon to heterocysts. Several routes have been described for metabolite exchange within the filament, one of which involves communicating channels that penetrate the septum between adjacent cells. Several fra gene mutants were isolated 25 y ago on the basis of their phenotypes: inability to fix nitrogen and fragmentation of filaments upon transfer from N+ to N− media. Cryopreservation combined with electron tomography were used to investigate the role of three fra gene products in channel formation. FraC and FraG are clearly involved in channel formation, whereas FraD has a minor part. Additionally, FraG was located close to the cytoplasmic membrane and in the heterocyst neck, using immunogold labeling with antibody raised to the N-terminal domain of the FraG protein. PMID:26216997

  4. School Business Administration.

    ERIC Educational Resources Information Center

    Jordan, K. Forbis; Webb, L. Dean

    1986-01-01

    Reviews the societal and organizational changes affecting school business administration, describes major activities encompassed in the practice of school business administration, and reviews current literature specifically related to such activities as electronic data processing, fiscal planning and budgeting, purchasing and property management,…

  5. AN ANALYSIS OF THE RATIONALE AND PROCEDURES FOR LONG-RANGE PLANNING --FOUND IN SELECTED CORPORATE ENTERPRISES, GOVERNMENT AGENCIES OR DEPARTMENTS, AND SCHOOL SYSTEMS--WHICH ARE APPROPRIATE FOR EDUCATIONAL AND ADMINISTRATIVE PLANNING IN LOCAL SCHOOL SYSTEMS.

    ERIC Educational Resources Information Center

    RULIFFSON, WILLARD ADAMS

    THIS STUDY REVIEWS SOME OF THE CURRENT PLANNING PRACTICES IN SCHOOL SYSTEMS WHICH ARE CONSIDERED TO BE ALREADY INVOLVED IN LONG-RANGE PLANNING, AND DESCRIBES FURTHER LONG-RANGE TECHNIQUES WHICH COULD BE ADAPTED FOR SCHOOL SYSTEMS FROM CURRENT CORPORATE AND GOVERNMENTAL PLANNING PROCEDURES. INDIVIDUAL INTERVIEWS WERE CONDUCTED WITH SELECTED…

  6. The Strawberry Pathogenesis-related 10 (PR-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates*

    PubMed Central

    Casañal, Ana; Zander, Ulrich; Muñoz, Cristina; Dupeux, Florine; Luque, Irene; Botella, Miguel Angel; Schwab, Wilfried; Valpuesta, Victoriano; Marquez, José A.

    2013-01-01

    Pathogenesis-related 10 (PR-10) proteins are involved in many aspects of plant biology but their molecular function is still unclear. They are related by sequence and structural homology to mammalian lipid transport and plant abscisic acid receptor proteins and are predicted to have cavities for ligand binding. Recently, three new members of the PR-10 family, the Fra a proteins, have been identified in strawberry, where they are required for the activity of the flavonoid biosynthesis pathway, which is essential for the development of color and flavor in fruits. Here, we show that Fra a proteins bind natural flavonoids with different selectivity and affinities in the low μm range. The structural analysis of Fra a 1 E and a Fra a 3-catechin complex indicates that loops L3, L5, and L7 surrounding the ligand-binding cavity show significant flexibility in the apo forms but close over the ligand in the Fra a 3-catechin complex. Our findings provide mechanistic insight on the function of Fra a proteins and suggest that PR-10 proteins, which are widespread in plants, may play a role in the control of secondary metabolic pathways by binding to metabolic intermediates. PMID:24133217

  7. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism.

    PubMed

    Bozec, Aline; Bakiri, Latifa; Jimenez, Maria; Rosen, Evan D; Catalá-Lehnen, Philip; Schinke, Thorsten; Schett, Georg; Amling, Michael; Wagner, Erwin F

    2013-12-01

    Recent studies have established that the skeleton functions as an endocrine organ affecting metabolism through the osteoblast-derived hormone osteocalcin (Ocn). However, it is not fully understood how many transcription factors expressed in osteoblasts regulate the endocrine function. Here, we show that mice with osteoblast-specific deletion of Fra-2 (Fosl2) have low bone mass but increased body weight. In contrast, transgenic expression of Fra-2 in osteoblasts leads to increased bone mass and decreased body weight accompanied by reduced serum glucose and insulin levels, improved glucose tolerance and insulin sensitivity. In addition, mice lacking Fra-2 have reduced levels of circulating Ocn, but high adiponectin (Adipoq), whereas Fra-2 transgenic mice exhibit high Ocn and low Adipoq levels. Moreover, we found that Adipoq was expressed in osteoblasts and that this expression was transcriptionally repressed by Fra-2. These results demonstrate that Fra-2 expression in osteoblasts represents a novel paradigm for a transcription factor controlling the endocrine function of the skeleton. PMID:24046454

  8. An Analysis of the Need for Medical Record Administration Programs in New Jersey. Manpower Planning Series. Office of Research and Manpower, Volume 1, Report Number 3.

    ERIC Educational Resources Information Center

    Rineberg, Joan

    The need for medical record administrators in New Jersey, and specifically in hospitals, was studied using a methodology that projects requirements and accounts for the utilization of Registered Record Administrators (RRAs) in alternative health care settings by 1990. Furthermore, employment opportunities in such nontraditional settings as…

  9. Head of Administration

    NASA Astrophysics Data System (ADS)

    2005-03-01

    Purpose and scope of the position: The main task is to provide efficient administrative services and advice to the Director General, Division Leaders and to staff members in the scientific and technical areas in the fields of financial planning and accounting, personnel management, purchasing, legal and contractual matters, information systems and building and site maintenance. As a member of the ESO Management the Head of Administration contributes essentially to the development of the overall policy, strategic planning, relations to the members of the personnel and maintains professional contacts at highest level outside the Organisation. ESO employs in total approximately 650 staff members and the Administration Division comprises the Administration at the Headquarters in Garching near Munich and the Administration in Santiago (Chile). The successful candidate will be supported by some 50 qualified staff members.

  10. Energy planning and management plan

    SciTech Connect

    1996-01-01

    This paper contains printed copies of 60FR 53181, October 12, 1995 and 60 FR 54151. This is a record of decision concerning the Western Area Power Administration`s final draft and environmental impact statement, and Energy Planning and Management Program.

  11. Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression.

    PubMed

    Bakiri, L; Macho-Maschler, S; Custic, I; Niemiec, J; Guío-Carrión, A; Hasenfuss, S C; Eger, A; Müller, M; Beug, H; Wagner, E F

    2015-02-01

    Epithelial-to-mesenchymal transition (EMT) is essential for embryonic morphogenesis and wound healing and critical for tumour cell invasion and dissemination. The AP-1 transcription factor Fra-1 has been implicated in tumorigenesis and in tumour-associated EMT in human breast cancer. We observed a significant inverse correlation between Fra-1 mRNA expression and distant-metastasis-free survival in a large cohort of breast cancer patients derived from multiple array data sets. This unique correlation among Fos genes prompted us to assess the evolutionary conservation between Fra-1 functions in EMT of human and mouse cells. Ectopic expression of Fra-1 in fully polarized, non-tumourigenic, mouse mammary epithelial EpH4 cells induced a mesenchymal phenotype, characterized by a loss of epithelial and gain of mesenchymal markers. Proliferation, motility and invasiveness were also increased in the resulting EpFra1 cells, and the cells were tumourigenic and efficiently colonized the lung upon transplantation. Molecular analyses revealed increased expression of Tgfβ1 and the EMT-inducing transcription factors Zeb1, Zeb2 and Slug. Mechanistically, Fra-1 binds to the tgfb1 and zeb2 promoters and to an evolutionarily conserved region in the first intron of zeb1. Furthermore, increased activity of a zeb2 promoter reporter was detected in EpFra1 cells and shown to depend on AP-1-binding sites. Inhibiting TGFβ signalling in EpFra1 cells moderately increased the expression of epithelial markers, whereas silencing of zeb1 or zeb2 restored the epithelial phenotype and decreased migration in vitro and tumorigenesis in vivo. Thus Fra-1 induces changes in the expression of genes encoding EMT-related transcription factors leading to the acquisition of mesenchymal, invasive and tumorigenic capacities by epithelial cells. This study defines a novel function of Fra-1/AP-1 in modulating tgfb1, zeb1 and zeb2 expression through direct binding to genomic regulatory regions, which establishes

  12. Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression

    PubMed Central

    Bakiri, L; Macho-Maschler, S; Custic, I; Niemiec, J; Guío-Carrión, A; Hasenfuss, S C; Eger, A; Müller, M; Beug, H; Wagner, E F

    2015-01-01

    Epithelial-to-mesenchymal transition (EMT) is essential for embryonic morphogenesis and wound healing and critical for tumour cell invasion and dissemination. The AP-1 transcription factor Fra-1 has been implicated in tumorigenesis and in tumour-associated EMT in human breast cancer. We observed a significant inverse correlation between Fra-1 mRNA expression and distant-metastasis-free survival in a large cohort of breast cancer patients derived from multiple array data sets. This unique correlation among Fos genes prompted us to assess the evolutionary conservation between Fra-1 functions in EMT of human and mouse cells. Ectopic expression of Fra-1 in fully polarized, non-tumourigenic, mouse mammary epithelial EpH4 cells induced a mesenchymal phenotype, characterized by a loss of epithelial and gain of mesenchymal markers. Proliferation, motility and invasiveness were also increased in the resulting EpFra1 cells, and the cells were tumourigenic and efficiently colonized the lung upon transplantation. Molecular analyses revealed increased expression of Tgfβ1 and the EMT-inducing transcription factors Zeb1, Zeb2 and Slug. Mechanistically, Fra-1 binds to the tgfb1 and zeb2 promoters and to an evolutionarily conserved region in the first intron of zeb1. Furthermore, increased activity of a zeb2 promoter reporter was detected in EpFra1 cells and shown to depend on AP-1-binding sites. Inhibiting TGFβ signalling in EpFra1 cells moderately increased the expression of epithelial markers, whereas silencing of zeb1 or zeb2 restored the epithelial phenotype and decreased migration in vitro and tumorigenesis in vivo. Thus Fra-1 induces changes in the expression of genes encoding EMT-related transcription factors leading to the acquisition of mesenchymal, invasive and tumorigenic capacities by epithelial cells. This study defines a novel function of Fra-1/AP-1 in modulating tgfb1, zeb1 and zeb2 expression through direct binding to genomic regulatory regions, which establishes

  13. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration (Report and Appendix)

    SciTech Connect

    Eudy, L.; Chandler, K.

    2008-05-01

    This document describes the hydrogen transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's Federal Transit Administration (FTA).

  14. Adapting and Testing Business Management Development Programs for Educational Administrators. Volume 4 of 6 Volumes. Appendix G-Planning Document: North Carolina SEA, Program Services. Appendix H-Planning Document: North Carolina LEA, Cabarrus County. Final Report.

    ERIC Educational Resources Information Center

    Klawuhn, Raymond E.; Basso, Alexander J.

    This document is comprised of two appendixes that provide a portion of the materials utilized in the project to test the feasibility of adapting business management practices to educational institutions. Included are the educational planning process documents for two of the eight participating management teams. Each planning process document…

  15. Adapting and Testing Business Management Development Programs for Educational Administrators. Volume 3 of 6 Volumes. Appendix E-Planning Document: Maryland LEA, Prince George's Co., Appendix F-Planning Document: North Carolina SEA, Executive Staff. Final Report.

    ERIC Educational Resources Information Center

    Klawuhn, Raymond E.; Basso, Alexander J.

    This document is comprised of two appendixes that provide a portion of the materials utilized in the project to test the feasibility of adapting business management practices to educational institutions. Included are the educational planning process documents for two of the eight participating management teams. Each planning process document…

  16. Dual role for mitogen-activated protein kinase (Erk) in insulin-dependent regulation of Fra-1 (fos-related antigen-1) transcription and phosphorylation.

    PubMed Central

    Hurd, Toby W; Culbert, Ainsley A; Webster, Kenneth J; Tavaré, Jeremy M

    2002-01-01

    Insulin regulates the activity of the AP-1 (activator protein-1) transcriptional complex in several cell types. One component of the AP-1 complex is the transcription factor Fra-1 (fos-related antigen-1), and we have demonstrated previously that insulin stimulates the expression of Fra-1 mRNA in CHO.T cells [Griffiths, Black, Culbert, Dickens, Shaw, Gillespie and Tavaré (1998) Biochem. J. 335, 19-26]. Here we demonstrate that insulin stimulates the activity of a fra-1 promoter linked to a luciferase reporter gene, indicating that the ability of insulin to induce expression of Fra-1 mRNA is due, at least in part, to an increase in gene transcription. Furthermore, we found that insulin induces the serine phosphorylation of Fra-1 and reduces its mobility during SDS/PAGE as a result of phosphorylation. The ability of insulin to induce the accumulation of Fra-1 mRNA, stimulate the fra-1 promoter and stimulate phosphorylation of Fra-1 all require the mitogen-activated protein (MAP) kinase cascade, which leads to the activation of extracellular-signal-regulated kinase (Erk) 1/2. Consequently, our results demonstrate that the Erk cascade plays a dual role in the co-ordinated regulation of the transcription and the phosphorylation of Fra-1 by insulin. PMID:12197835

  17. Apollo 14 mineral ages and the thermal history of the Fra Mauro formation.

    NASA Technical Reports Server (NTRS)

    Compston, W.; Vernon, M. J.; Berry, H.; Rudowski, R.; Gray, C. M.; Ware, N.; Chappell, B. W.; Kaye, M.

    1972-01-01

    The thermal inertia of the Fra Mauro formation limits its rate of cooling. The calculations of Jaeger (1961) for the cooling of an extrusive sheet are used to estimate the time required for a central temperature drop of 10%. This time is found to be about 45 years. For a 90% temperature drop, the time is about 200 years. Analytical methods used in the investigations are discussed together with the diffusion of Rb and Sr within lunar basalt. Isochron diagrams for various minerals are presented.

  18. Adult Education Program Performance Report. Fiscal Year 1994. Under the Four-Year Plan for the Administration of Adult Education, P.L. 102-73.

    ERIC Educational Resources Information Center

    Guam Community Coll., Agana. Office of the State Director for Adult Education.

    Guam Community College provides basic skills education for adults who have less than high school education. In 1994, these services were provided at 11 sites by 20 administrative and support personnel, 70 teachers, and 6 counselors (88 of these work part time). In that year, more than 2,000 adults enrolled in programs to enhance their skills and…

  19. Formacion de Formadores: Experiencias Institucionales en Planeamiento y Administracion de la Educacion. (The Formation of Educational Planners: Institutional Experiences in Planning and Administration for Education.

    ERIC Educational Resources Information Center

    Senen Gonzalez, Silvia N. de

    Information collected from interviews with 15 ministers of education and 30 program directors and researchers at 18 universities in Venezuela, Costa Rica, Chile, Mexico, Colombia, Brazil, and Argentina is used to study academic programs which prepare persons to be educational planners and administrators. Section one describes background…

  20. State of Rhode Island Department of Administration Office of Library and Information Services. Five-Year State Plan for the Fiscal Years 2008 to 2012

    ERIC Educational Resources Information Center

    Rhode Island Office of Library and Information Services, 2008

    2008-01-01

    In preparation for its Five-Year Plan for the years 2008 through 2012, the Rhode Island Office of Library and Information Services has reviewed a variety of information resources, including studies, publications, surveys and stakeholder meetings, to assist in understanding the state, its people, its future and the potential role of libraries. This…

  1. Adult Education Program Performance Report. Program Year 1996. Under the Four-Year Plan for the Administration of Adult Education P.L. 102-73.

    ERIC Educational Resources Information Center

    Guam Community Coll., Agana. Office of the State Director for Adult Education.

    The Guam State Plan for Adult Education, as implemented by Guam Community College, had five goals: provide a comprehensive adult education instructional program that is flexible and responsive to employment needs; increase enrollment and expand services for special groups; establish continuous needs assessment of targeted educationally…

  2. Budget Planning and Administrative Coordination: A Case Study--The University of Minnesota. Resource Allocation Management in Higher Education. Reporting and Communicating.

    ERIC Educational Resources Information Center

    Moos, Malcolm C.

    1972-01-01

    The financial crunch hit the University of Minnesota after the 1971 legislative session, which appropriated for the 1971-72 and 1972-73 fiscal years and began an attempt at a new kind of budget planning process. It was a unique process in the institutional review of programs and in the setting of priorities for future growth and direction. There…

  3. Faculty and Administrator's Perceptions of the Utilization of the Accrediting Commission for Community and Junior Colleges (ACCJC) Program Review and Planning Rubrics

    ERIC Educational Resources Information Center

    Grossman, David H.

    2014-01-01

    California community colleges have been inconsistent in their efforts to meet the program review and planning accreditation standards established by the Accrediting Commission for Community and Junior Colleges (ACCJC). To assist colleges in their effort to meet the accreditation standards and to improve educational quality, the ACCJC developed the…

  4. The Generalisation of Educational Innovations: The Administrator's Perspective. Contributions to a Workshop Held at the International Institute for Educational Planning (Paris, France, December 8-10, 1980).

    ERIC Educational Resources Information Center

    Malpica, Carlos

    Twelve papers were presented at a 1980 International Institute for Educational Planning (IIEP) workshop on the generalization of educational innovations from the local to the national level. Six of these papers are published in this report, along with a substantial bibliography and an introductory chapter summarizing the papers and describing the…

  5. Administrative Synergy

    ERIC Educational Resources Information Center

    Hewitt, Kimberly Kappler; Weckstein, Daniel K.

    2012-01-01

    One of the biggest obstacles to overcome in creating and sustaining an administrative professional learning community (PLC) is time. Administrators are constantly deluged by the tyranny of the urgent. It is a Herculean task to carve out time for PLCs, but it is imperative to do so. In this article, the authors describe how an administrative PLC…

  6. Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes.

    PubMed

    Mechaly, Ariel E; Bellomio, Augusto; Morante, Koldo; Agirre, Jon; Gil-Cartón, David; Valle, Mikel; González-Mañas, Juan Manuel; Guérin, Diego M A

    2012-11-01

    The recent high-resolution structure of the toxin FraC derived from the sea anemone Actinia fragacea has provided new insight into the mechanism of pore formation by actinoporins. In this work, we report two new crystal forms of FraC in its oligomeric prepore conformation. Together with the previously reported structure, these two new structures reveal that ring-like nonamers of the toxin assemble into compact two-dimensional hexagonal arrays. This supramolecular organization is maintained in different relative orientations adopted by the oligomers within the crystal layers. Analyses of the aggregation of FraC pores in both planar and curved (vesicles) model membranes show similar 2D hexagonal arrangements. Our observations support a model in which hexagonal pore-packing is a clustering mechanism that maximizes toxin-driven membrane damage in the target cell. PMID:22728830

  7. FRA-1 as a driver of tumour heterogeneity: a nexus between oncogenes and embryonic signalling pathways in cancer.

    PubMed

    Dhillon, A S; Tulchinsky, E

    2015-08-20

    Tumour heterogeneity is a major factor undermining the success of therapies targeting metastatic cancer. Two major theories are thought to explain the phenomenon of heterogeneity in cancer--clonal evolution and cell plasticity. In this review, we examine a growing body of work implicating the transcription factor FOS-related antigen 1 (FRA-1) as a central node in tumour cell plasticity networks, and discuss mechanisms regulating its activity in cancer cells. We also discuss evidence from the FRA-1 perspective supporting the notion that clonal selection and cell plasticity represent two sides of the same coin. We propose that FRA-1-overexpressing clones featuring high plasticity undergo positive selection during consecutive stages of multistep tumour progression. This model underscores a potential mechanism through which tumour cells retaining elevated levels of plasticity acquire a selective advantage over other clonal populations within a tumour. PMID:25381818

  8. Project Plan for Taft-Bell 500 KV Transmission Line on Federal Lands Administrated by United States Department of Interior, Bureau of Land Management and United States Department of Agriculture Forest Service, Construction by Bonneville Power Administration.

    SciTech Connect

    Gillard, C.E.; Miller, C.S.

    1985-08-01

    The project described includes the Taft-Bell 500 kV Transmission Line. This facility crosses 52.05 miles of National Forest System lands, and 2.54 miles of lands managed by the Bureau of Land Management. Between the Coeur d'Alene River and Wallace, a 10.5 mile portion will parallel the Washington Water Power Company's Noxon-Wallace-Pine Creek 230 kV Transmission Line. BPA will do road construction and right-of-way clearing for both The Washington Water Power Company and BPA transmission lines in this parallel area. This Project Plan is a compilation of Points of Agreement. It is intended to serve as permanent documentation and as a field guide during the construction period.

  9. 40 CFR 60.27 - Actions by the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Actions by the Administrator. 60.27... Designated Facilities § 60.27 Actions by the Administrator. (a) The Administrator may, whenever he determines... receipt of a plan or plan revision, the Administrator will propose the plan or revision for approval...

  10. 40 CFR 60.27 - Actions by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Actions by the Administrator. 60.27... Designated Facilities § 60.27 Actions by the Administrator. (a) The Administrator may, whenever he determines... receipt of a plan or plan revision, the Administrator will propose the plan or revision for approval...

  11. 40 CFR 60.27 - Actions by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Actions by the Administrator. 60.27... Designated Facilities § 60.27 Actions by the Administrator. (a) The Administrator may, whenever he determines... receipt of a plan or plan revision, the Administrator will propose the plan or revision for approval...

  12. 40 CFR 60.27 - Actions by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Actions by the Administrator. 60.27... Designated Facilities § 60.27 Actions by the Administrator. (a) The Administrator may, whenever he determines... receipt of a plan or plan revision, the Administrator will propose the plan or revision for approval...

  13. A Treatise on Administration.

    ERIC Educational Resources Information Center

    Moore, Thomas R.

    1988-01-01

    Expands Henri Fayol's definition of the administrative process to include a humanistic approach involving planning, organizing, implementing, controlling, evaluating, and satisfying functions. This empirical definition differs from some theoretical approaches by looking beyond resource consumption to consider ecological effects on the environment…

  14. Administrative Utility Analysis: Appendices.

    ERIC Educational Resources Information Center

    Peat, Marwick, Mitchell and Co., San Juan, Puerto Rico.

    Appendixes to a study on administrative utility analysis and vocational education programs for the Area of Vocational and Technical Education (AVTE) in the Puerto Rico Department of Education contain the planning and budgeting system elements, position descriptions, and information on the growth of vocational education in Puerto Rico. The elements…

  15. Survey Plan For Characterization of the Subsurface Underlying the National Aeronautics and Space Administration's Marshall Space Flight Center in Huntsville, Alabama. Volume 1 and 2

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Topic considered include: survey objectives; technologies for non-Invasive imaging of subsurface; cost; data requirements and sources; climatic condition; hydrology and geology; chemicals; magnetometry; electrical(resistivity, potential); optical-style imaging; reflection/refraction seismics; gravitometry; photo-acoustic activation;well drilling and borehole analysis; comparative assessment matrix; ground sensors; choice of the neutron sources; logistic of operations; system requirements; health and safety plans.

  16. 49 CFR Appendix F to Part 236 - Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System Safety...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Minimum Requirements of FRA Directed Independent... F to Part 236—Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System... independent third-party assessment of PTC system safety verification and validation pursuant to subpart H or...

  17. 49 CFR Appendix F to Part 236 - Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System Safety...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Minimum Requirements of FRA Directed Independent... F to Part 236—Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System... independent third-party assessment of PTC system safety verification and validation pursuant to subpart H or...

  18. 49 CFR Appendix F to Part 236 - Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System Safety...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Minimum Requirements of FRA Directed Independent... F to Part 236—Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System... independent third-party assessment of PTC system safety verification and validation pursuant to subpart H or...

  19. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2

    PubMed Central

    Wurm, Stefanie; Zhang, Jisheng; Guinea-Viniegra, Juan; García, Fernando; Muñoz, Javier; Bakiri, Latifa; Ezhkova, Elena

    2015-01-01

    Altered epidermal differentiation characterizes numerous skin diseases affecting >25% of the human population. Here we identified Fra-2/AP-1 as a key regulator of terminal epidermal differentiation. Epithelial-restricted, ectopic expression of Fra-2 induced expression of epidermal differentiation genes located within the epidermal differentiation complex (EDC). Moreover, in a papilloma-prone background, a reduced tumor burden was observed due to precocious keratinocyte differentiation by Fra-2 expression. Importantly, loss of Fra-2 in suprabasal keratinocytes is sufficient to cause skin barrier defects due to reduced expression of differentiation genes. Mechanistically, Fra-2 binds and transcriptionally regulates EDC gene promoters, which are co-occupied by the transcriptional repressor Ezh2. Fra-2 remains transcriptionally inactive in nondifferentiated keratinocytes, where it was found monomethylated and dimethylated on Lys104 and interacted with Ezh2. Upon keratinocyte differentiation, Fra-2 is C-terminally phosphorylated on Ser320 and Thr322 by ERK1/2, leading to transcriptional activation. Thus, the induction of epidermal differentiation by Fra-2 is controlled by a dual mechanism involving Ezh2-dependent methylation and activation by ERK1/2-dependent phosphorylation. PMID:25547114

  20. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2.

    PubMed

    Wurm, Stefanie; Zhang, Jisheng; Guinea-Viniegra, Juan; García, Fernando; Muñoz, Javier; Bakiri, Latifa; Ezhkova, Elena; Wagner, Erwin F

    2015-01-15

    Altered epidermal differentiation characterizes numerous skin diseases affecting >25% of the human population. Here we identified Fra-2/AP-1 as a key regulator of terminal epidermal differentiation. Epithelial-restricted, ectopic expression of Fra-2 induced expression of epidermal differentiation genes located within the epidermal differentiation complex (EDC). Moreover, in a papilloma-prone background, a reduced tumor burden was observed due to precocious keratinocyte differentiation by Fra-2 expression. Importantly, loss of Fra-2 in suprabasal keratinocytes is sufficient to cause skin barrier defects due to reduced expression of differentiation genes. Mechanistically, Fra-2 binds and transcriptionally regulates EDC gene promoters, which are co-occupied by the transcriptional repressor Ezh2. Fra-2 remains transcriptionally inactive in nondifferentiated keratinocytes, where it was found monomethylated and dimethylated on Lys104 and interacted with Ezh2. Upon keratinocyte differentiation, Fra-2 is C-terminally phosphorylated on Ser320 and Thr322 by ERK1/2, leading to transcriptional activation. Thus, the induction of epidermal differentiation by Fra-2 is controlled by a dual mechanism involving Ezh2-dependent methylation and activation by ERK1/2-dependent phosphorylation. PMID:25547114

  1. 75 FR 2466 - State Highway-Rail Grade Crossing Action Plans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ...) published on November 13, 2009 (74 FR 58589), FRA proposed a rule to require the ten States with the most... Statement in the Federal Register published on April 11, 2000 (65 FR 19477-78) or you may visit http://www... Federal Railroad Administration 49 CFR Part 234 RIN 2130-AC20 State Highway-Rail Grade Crossing...

  2. Modernizing Administration.

    ERIC Educational Resources Information Center

    Lombardi, Vincent L.; Hildebrand, Verna

    1981-01-01

    Suggests assignment of research duties and rotation of teaching and management roles for college administrators, to increase their effectiveness and diminish the negative effects of declining enrollments. (JD)

  3. Fra a 1.02 Is the Most Potent Isoform of the Bet v 1-like Allergen in Strawberry Fruit.

    PubMed

    Franz-Oberdorf, Katrin; Eberlein, Bernadette; Edelmann, Kathrin; Hücherig, Stephanie; Besbes, Fatma; Darsow, Ulf; Ring, Johannes; Schwab, Wilfried

    2016-05-11

    The strawberry fruit proteins Fra a 1.01E-1.08 are homologues of the major birch pollen allergen Bet v 1. Three of the proteins are known to have essential biological functions in pigment formation during fruit ripening and seem to be responsible for allergic reactions to strawberry fruit. We evaluated the cross-reactive allergenic potential of these putative strawberry allergens in patients allergic to birch pollen. Activation of basophils of eight atopic patients was studied using different concentrations of Fra a 1 isoforms. Bet v 1a was used as control and as atopic patient selection criterion. Although Fra a 1.01E-1.08 have amino acid sequence identities of 74.5-97.5% with Fra a 1.02, the basophil activation mediated by the eight Fra a 1 proteins differed substantially. Fra a 1.03 and Fra a 1.02 showed the highest activation of basophils, 73 and 66% of total basophils, respectively. On the basis of the high relative expression of the gene Fra a 1.02 in ripe strawberry fruits of allergenic varieties, Fra a 1.02 was identified as the main strawberry allergen of the Bet v 1 superfamily. Knowledge of the allergenic potential of Fra a 1.02/1.03 will help to improve food safety and can serve as a valuable marker for the development of red-fruited hypoallergenic strawberry cultivars. PMID:27086707

  4. The Yeast Iron Regulatory Proteins Grx3/4 and Fra2 Form Heterodimeric Complexes Containing a [2Fe-2S] Cluster with Cysteinyl and Histidyl Ligation†

    PubMed Central

    Li, Haoran; Mapolelo, Daphne T.; Dingra, Nin N.; Naik, Sunil G.; Lees, Nicolas S.; Hoffman, Brian M.; Riggs-Gelasco, Pamela J.; Huynh, Boi Hanh; Johnson, Michael K.; Outten, Caryn E.

    2009-01-01

    The transcription of iron uptake and storage genes in S. cerevisiae is primarily regulated by the transcription factor Aft1. Nucleocytoplasmic shuttling of Aft1 is dependent upon mitochondrial Fe-S cluster biosynthesis via a signaling pathway that includes the cytosolic monothiol glutaredoxins (Grx3 and Grx4) and the BolA homologue Fra2. However the interactions between these proteins and the iron-dependent mechanism by which they control Aft1 localization are unclear. To reconstitute and characterize components of this signaling pathway in vitro, we have overexpressed yeast Fra2 and Grx3/4 in E. coli. We have shown that co-expression of recombinant Fra2 with Grx3 or Grx4 allows purification of a stable [2Fe-2S]2+ cluster-containing Fra2-Grx3 or Fra2-Grx4 heterodimeric complex. Reconstitution of a [2Fe-2S] cluster on Grx3 or Grx4 without Fra2 produces a [2Fe-2S]-bridged homodimer. UV-visible absorption and CD, resonance Raman, EPR, ENDOR, Mössbauer, and EXAFS studies of [2Fe-2S] Grx3/4 homodimers and the [2Fe-2S] Fra2-Grx3/4 heterodimers indicate that inclusion of Fra2 in the Grx3/4 Fe-S complex causes a change in the cluster stability and coordination environment. Taken together, our analytical, spectroscopic, and mutagenesis data indicate that Grx3/4 and Fra2 form a Fe-S-bridged heterodimeric complex with Fe ligands provided by the active site cysteine of Grx3/4, glutathione, and a histidine residue. Overall, these results suggest that the ability of the Fra2-Grx3/4 complex to assemble a [2Fe-2S] cluster may act as a signal to control the iron regulon in response to cellular iron status in yeast. PMID:19715344

  5. Administrative Support.

    ERIC Educational Resources Information Center

    Doran, Dorothy; And Others

    This guide is intended to assist business education teachers in administrative support courses. The materials presented are based on the Arizona validated occupational competencies and tasks for the occupations of receptionist, secretary, and administrative assistant. Word processing skills have been infused into each of the three sections. The…

  6. Administrative Ecology

    ERIC Educational Resources Information Center

    McGarity, Augustus C., III; Maulding, Wanda

    2007-01-01

    This article discusses how all four facets of administrative ecology help dispel the claims about the "impossibility" of the superintendency. These are personal ecology, professional ecology, organizational ecology, and community ecology. Using today's superintendency as an administrative platform, current literature describes a preponderance of…

  7. Fracture network evaluation program (FraNEP): A software for analyzing 2D fracture trace-line maps

    NASA Astrophysics Data System (ADS)

    Zeeb, Conny; Gomez-Rivas, Enrique; Bons, Paul D.; Virgo, Simon; Blum, Philipp

    2013-10-01

    Fractures, such as joints, faults and veins, strongly influence the transport of fluids through rocks by either enhancing or inhibiting flow. Techniques used for the automatic detection of lineaments from satellite images and aerial photographs, LIDAR technologies and borehole televiewers significantly enhanced data acquisition. The analysis of such data is often performed manually or with different analysis software. Here we present a novel program for the analysis of 2D fracture networks called FraNEP (Fracture Network Evaluation Program). The program was developed using Visual Basic for Applications in Microsoft Excel™ and combines features from different existing software and characterization techniques. The main novelty of FraNEP is the possibility to analyse trace-line maps of fracture networks applying the (1) scanline sampling, (2) window sampling or (3) circular scanline and window method, without the need of switching programs. Additionally, binning problems are avoided by using cumulative distributions, rather than probability density functions. FraNEP is a time-efficient tool for the characterisation of fracture network parameters, such as density, intensity and mean length. Furthermore, fracture strikes can be visualized using rose diagrams and a fitting routine evaluates the distribution of fracture lengths. As an example of its application, we use FraNEP to analyse a case study of lineament data from a satellite image of the Oman Mountains.

  8. Key Obama officials leave administration

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2013-01-01

    Secretary of the Interior Ken Salazar is one of the latest members of the Obama administration to announce that he is leaving his position near the start of President Obama's second term in office. Salazar, who has served as interior secretary since January 2009, intends to leave the department by the end of March, the department noted on 16 January. Salazar joins a number of other key officials who are planning to leave the administration. They include Environmental Protection Agency administrator Lisa Jackson, National Oceanic and Atmospheric Administration administrator Jane Lubchenco, and U.S. Geological Survey director Marcia McNutt.

  9. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Administrative costs. 96.88 Section 96.88 Public... Assistance Program § 96.88 Administrative costs. (a) Costs of planning and administration. Any expenditure... be included in determining administrative costs subject to the statutory limitation on...

  10. 49 CFR 234.11 - State highway-rail grade crossing action plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... highway-rail grade crossing collisions, on average, during the calendar years 2006, 2007, and 2008. (c... crossings, including highway-rail grade crossing closures or grade separations; (ii) Focus on crossings that... State on the development of an FRA approved State highway-rail grade crossing action plan....

  11. 49 CFR 234.11 - State highway-rail grade crossing action plans.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... highway-rail grade crossing collisions, on average, during the calendar years 2006, 2007, and 2008. (c... crossings, including highway-rail grade crossing closures or grade separations; (ii) Focus on crossings that... State on the development of an FRA approved State highway-rail grade crossing action plan....

  12. 49 CFR 234.11 - State highway-rail grade crossing action plans.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... highway-rail grade crossing collisions, on average, during the calendar years 2006, 2007, and 2008. (c... crossings, including highway-rail grade crossing closures or grade separations; (ii) Focus on crossings that... State on the development of an FRA approved State highway-rail grade crossing action plan....

  13. Coaches Guide to Sport Administration.

    ERIC Educational Resources Information Center

    Leith, Larry M.

    This guide for athletic coaches offers a practical approach to the administrative functions of organizing, planning, leading, and controlling. Included are chapters on coaching administration, fund raising, organizing competitions, and designing effective budgets and controls. The guide addresses the following topics: (1) the categories of…

  14. The Enigma of Administrative Behaviour.

    ERIC Educational Resources Information Center

    Batchler, Merv

    1981-01-01

    Writers attempting to describe administration have approached the subject from a number of perspectives. Researchers such as Gulick (1937) identified planning, organizing, staffing, directing, coordinating, reporting, and budgeting as functional elements of administration. Hemphill, Griffiths, and Fredericksen (1962), using simulated job settings,…

  15. The Library Administrator's Automation Handbook.

    ERIC Educational Resources Information Center

    Boss, Richard W.

    One of the most significant decisions in a library administrator's career is the decision to automate one or more of a library's operations. This book describes the present state of local library automation; the planning, selection, and implementation process; and the library administrator's role in the process. The bulk of the text provides a…

  16. Cooperation between public administration and scientific research in raising awareness on the role of urban planning in responding to climate change in Portugal

    NASA Astrophysics Data System (ADS)

    Alcoforado, M. J.; Campos, V.; Oliveira, S.; Andrade, H.; Festas, M. J.

    2009-09-01

    Following the IPCC predictions of climate change, even considering one of the "best” scenarios (B1), temperature will rise circa 2°C by 2100. In southern Europe, predictions also indicate a greater precipitation variability, that is the increase in drought frequency, together with an increment of flood risk, with detrimental impacts on water availability and quality, summer tourism and crop productivity, among others. Urban areas create their own local climate, resulting in higher temperatures (UHI), modified wind patterns and lower air quality, among several other consequences. Therefore, as a result of both global and urban induced changes, the climate of cities has suffered several modifications over time, particularly in sprawling urban areas. In November 2007, the ministers responsible for spatial planning and territorial cohesion of the European Union, gathered at the Azores Informal Ministerial on Territorial Cohesion during the Portuguese Presidency, considered climate change to be one of the most important territorial challenges Europe is facing and stated that "our cities and regions need to become more resilient in the context of climate change”. They also agreed that spatial and urban planning is a suitable tool to define cost-effective adaptation measures. Furthermore, the Ministers committed themselves to put mitigation and adaptation issues of climate change into the mainstream of spatial and urban development policy at national, regional and local level. These decisions have lead to different actions in the Member States. In Portugal, the new Policy for the Cities POLIS XXI has selected the relationship between climate change and urban development as one of the key issues to be addressed by projects initiated by local authorities and submitted for co-financing through the OP "Territorial Enhancement” of the NSRF. This paper presents one of the actions taken by the Portuguese Directorate General for Spatial Planning and Urban Development

  17. The Administration's Private Pension Proposal.

    ERIC Educational Resources Information Center

    American Enterprise Inst. for Public Policy Research, Washington, DC.

    This report examines legislation proposed by the Nixon administration to (1) make available to employed workers a new type of personal retirement plan having tax-deferral advantages, (2) apply pre-retirement vesting requirements to the private pension system, and (3) broaden tax-deferred retirement plans presently available to the self-employed…

  18. 40 CFR 172.23 - State plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., by submitting a State plan, request the Administrator to authorize the designated State agency to... submit a State plan in writing to the Administrator. (b) Contents. A State plan shall include— (1) A... acceptance of State plan. (1) The Administrator shall grant authorization to issue experimental use...

  19. An evaluation of an initiative to improve Veterans Health Administration mental health services: broad impacts of the VHA's Mental Health Strategic Plan.

    PubMed

    Greenberg, Greg A; Rosenheck, Robert A

    2009-12-01

    In federal fiscal year (FY) 2005 the Department of Veterans Affairs (VA) implemented the comprehensive Mental Health Strategic Plan (MHSP). This study used performance measures from six broad domains to examine changes in the overall delivery of mental health services in the VA since the implementation of the MHSP. Performance measures from fiscal year 2004, the year before implementation of the MHSP, were compared with measures from fiscal years 2005, 2006, and 2007, the first 3 years of MHSP implementation. We combined heterogeneous performance measures within domains through the use of standardized scores or "z-scores." An overall improvement of 0.32 standardized units was observed from FY 2004 to FY 2007, representing moderate to large changes by conventional standards. The domains with the greatest improvement (>1.0 standard deviation units) from FY 2004 to FY 2007 were population coverage/access, outpatient care quality, economic performance (primarily efficiency), and global functioning. There was a 0.3 standard deviation decline in inpatient satisfaction and a slight increase in reliance on inpatient care. Overall improvement in VA mental health care was thus substantial and continuing. PMID:20055066

  20. Monitoring thermal stresses and incipient buckling of continuous-welded rails: results from the UCSD/BNSF/FRA large-scale laboratory test track

    NASA Astrophysics Data System (ADS)

    Phillips, Robert; Nucera, Claudio; Coccia, Stefano; Lanza di Scalea, Francesco; Bartoli, Ivan; Fateh, Mahmood; Carr, Gary

    2011-04-01

    Most modern railways use Continuous Welded Rail (CWR). A major problem is the almost total absence of expansion joints that can create buckling in hot weather and breakage in cold weather due to the rail thermal stresses. In June 2008 the University of California, San Diego (UCSD), under the sponsorship of a Federal Railroad Administration (FRA) Office of Research and Development (R&D) grant, began work to develop a technique for in-situ measurement of stress and detection of incipient buckling in CWR. The method under investigation is based on ultrasonic guided waves, and the ultimate goal is to develop a prototype that can be used in motion. A large-scale full rail track (70 feet in length) has been constructed at UCSD's Powell Structural Laboratories, the largest laboratories in the country for structural testing, to validate the CWR stress measurement and buckling detection technique under rail heating conditions well controlled in the laboratory. This paper will report on the results obtained from this unique large-scale test track to date. These results will pave the road for the future development of the rail stress measurement & buckling detection prototype.

  1. 5 CFR 1690.11 - Plan year.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Plan year. 1690.11 Section 1690.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD THRIFT SAVINGS PLAN Miscellaneous § 1690.11 Plan year. The Thrift Savings Plan's plan year is established on a calendar-year basis for all...

  2. 5 CFR 1690.11 - Plan year.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Plan year. 1690.11 Section 1690.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD THRIFT SAVINGS PLAN Miscellaneous § 1690.11 Plan year. The Thrift Savings Plan's plan year is established on a calendar-year basis for all...

  3. 5 CFR 1690.11 - Plan year.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Plan year. 1690.11 Section 1690.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD THRIFT SAVINGS PLAN Miscellaneous § 1690.11 Plan year. The Thrift Savings Plan's plan year is established on a calendar-year basis for all...

  4. 5 CFR 1690.11 - Plan year.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Plan year. 1690.11 Section 1690.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD THRIFT SAVINGS PLAN Miscellaneous § 1690.11 Plan year. The Thrift Savings Plan's plan year is established on a calendar-year basis for all...

  5. 5 CFR 1690.11 - Plan year.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Plan year. 1690.11 Section 1690.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD THRIFT SAVINGS PLAN Miscellaneous § 1690.11 Plan year. The Thrift Savings Plan's plan year is established on a calendar-year basis for all...

  6. Planning for School Emergencies.

    ERIC Educational Resources Information Center

    Della-Giustina, Daniel E.

    This document is designed to provide civil leaders and school administrators with a resource that will enable them to develop comprehensive contingency plans for specific emergency situations. A discussion of disaster and emergency management planning includes an outline of the objectives of emergency planning that were established for this guide.…

  7. Planning Homemaking Departments.

    ERIC Educational Resources Information Center

    Schooler, Ruth; Mather, Mary

    1961-01-01

    A comprehensive guide for home economists, the article treats five major ideas for planning home economics departments in schools, as follows--(1) the importance of sharing the planning responsibility among teacher, parent, and administrator, citing an example of successful planning, (2) the need for teaching methods, course content and equipment…

  8. Introduction to Health Planning.

    ERIC Educational Resources Information Center

    Bergwall, David F.; And Others

    This fundamental text is designed for students of both health care administration and comprehensive health planning. It is intended as a resource on the theory and process of health project planning with some mention of possible sources for further exploration. The emphasis is on how to develop a plan when the planner also has the authority to…

  9. Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling.

    PubMed

    Lau, Eunice Yuen Ting; Lo, Jessica; Cheng, Bowie Yik Ling; Ma, Mark Kin Fai; Lee, Joyce Man Fong; Ng, Johnson Kai Yu; Chai, Stella; Lin, Chi Ho; Tsang, Suk Ying; Ma, Stephanie; Ng, Irene Oi Lin; Lee, Terence Kin Wah

    2016-05-10

    Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesized that cancer-associated fibroblasts (CAFs) would regulate liver T-ICs. We found that the presence of α-SMA(+) CAFs correlates with poor clinical outcome. CAF-derived HGF regulates liver T-ICs via activation of FRA1 in an Erk1,2-dependent manner. Further functional analysis identifies HEY1 as a direct downstream effector of FRA1. Using the STAM NASH-HCC mouse model, we find that HGF-induced FRA1 activation is associated with the fibrosis-dependent development of HCC. Thus, targeting the CAF-derived, HGF-mediated c-Met/FRA1/HEY1 cascade may be a therapeutic strategy for the treatment of HCC. PMID:27134167

  10. Engineering Administration.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    This book is intended to acquaint naval engineering officers with their duties in the engineering department. Standard shipboard organizations are analyzed in connection with personnel assignments, division operations, and watch systems. Detailed descriptions are included for the administration of directives, ship's bills, damage control, training…

  11. ADMINISTRATIVE CLIMATE.

    ERIC Educational Resources Information Center

    BRUCE, ROBERT L.; CARTER, G.L., JR.

    IN THE COOPERATIVE EXTENSION SERVICE, STYLES OF LEADERSHIP PROFOUNDLY AFFECT THE QUALITY OF THE SERVICE RENDERED. ACCORDINGLY, MAJOR INFLUENCES ON ADMINISTRATIVE CLIMATE AND EMPLOYEE PRODUCTIVITY ARE EXAMINED IN ESSAYS ON (1) SOURCES OF JOB SATISFACTION AND DISSATISFACTION, (2) MOTIVATIONAL THEORIES BASED ON JOB-RELATED SATISFACTIONS AND NEEDS,…

  12. Database Administrator

    ERIC Educational Resources Information Center

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  13. Rb-Sr ages of igneous rocks from the Apollo 14 mission and the age of the Fra Mauro formation.

    NASA Technical Reports Server (NTRS)

    Papanastassiou, D. A.; Wasserburg, G. J.

    1971-01-01

    Internal Rb-Sr isochrons were determined on four basaltic rocks and on a basaltic clast from a breccia from the Fra Mauro landing site. An internal isochron was determined for rock 12004 and yielded a value in agreement with previous results for basaltic rocks from the Apollo 12 site. The crystallization ages for Apollo 14 basalts are only 0.2 to 0.3 AE older than were found for mare basalts from the Sea of Tranquility. Assuming these leucocratic igneous rocks to be representative of the Fra Mauro site, it follows that there were major igneous processes active in these regions, and presumably throughout the highlands, at times only slightly preceding the periods at which the maria were last flooded.

  14. SIRT1 promotes epithelial-mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expression.

    PubMed

    Cheng, Feifei; Su, Li; Yao, Chao; Liu, Limei; Shen, Junjie; Liu, Chungang; Chen, Xuejiao; Luo, Yongli; Jiang, Lupin; Shan, Juanjuan; Chen, Jun; Zhu, Wei; Shao, Jimin; Qian, Cheng

    2016-06-01

    Understanding molecular mechanisms of colorectal cancer (CRC) metastasis is urgently required for targeted therapy and prognosis of metastatic CRC. In this study, we explored potential effects of silent mating type information regulation 2 homolog 1 (SIRT1) on CRC metastasis. Our data showed that ectopic expression of SIRT1 markedly increased the migration and invasion of CRC cells. In contrast, silencing SIRT1 repressed this behavior in aggressive CRC cells. Tumor xenograft experiments revealed that knockdown of SIRT1 impaired CRC metastasis in vivo. Silencing SIRT1 in CRC cells induced mesenchymal-epithelial transition (MET), which is the reverse process of epithelial-mesenchymal transition (EMT) and characterized by a gain of epithelial and loss of mesenchymal markers. We provided a mechanistic insight toward regulation of Fra-1 by SIRT1 and demonstrated a direct link between the SIRT1-Fra-1 axis and EMT. Moreover, SIRT1 expression correlated positively with Fra-1 expression, metastasis and overall survival in patients with CRC. Taken together, our data provide a novel mechanistic role of SIRT1 in CRC metastasis, suggesting that SIRT1 may serve as a potential therapeutic target for metastatic CRC. PMID:26975631

  15. Do You Know Buildings? Facility Planning Knowledge and Skills.

    ERIC Educational Resources Information Center

    Glass, Thomas E.

    1994-01-01

    A school business administrator should be equipped to lead a district facility planning effort. Describes the processes of demographic planning, facility assessing, long-range financial facility plan budgeting, and aligning the facility plan with the district strategic plan. (MLF)

  16. 9 CFR 146.2 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Administration. 146.2 Section 146.2... Administration. (a) The Department cooperates through a Memorandum of Understanding with the Official State Agency in the administration of the Plan. In the Memorandum of Understanding, the Official State...

  17. 9 CFR 146.2 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Administration. 146.2 Section 146.2... Administration. (a) The Department cooperates through a Memorandum of Understanding with the Official State Agency in the administration of the Plan. In the Memorandum of Understanding, the Official State...

  18. 9 CFR 146.2 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Administration. 146.2 Section 146.2... Administration. (a) The Department cooperates through a Memorandum of Understanding with the Official State Agency in the administration of the Plan. In the Memorandum of Understanding, the Official State...

  19. College & University Business Administration. Third Edition.

    ERIC Educational Resources Information Center

    National Association of College and University Business Officers, Washington, DC.

    This text presents indepth coverage of five areas of college and university business administration, including administrative management, business management, fiscal management, and financial accounting and reporting. The section on administrative management encompasses institutional planning, management information systems and data processing,…

  20. Public Administration of Recreational Services. Second Edition.

    ERIC Educational Resources Information Center

    Hjelte, George; Shivers, Jay S.

    Oriented toward a consideration of administration from the standpoint of departmental problems, this textbook deals with administrative techniques and practices pertaining to public administration of recreational services. It covers organization, operation, planning, development, and managerial procedures, and also describes the basic elements of…

  1. Administrative Plan to Prevent High School Dropouts.

    ERIC Educational Resources Information Center

    Carnes, Ernest B.

    Recommendations for developing educational programs for high school dropout-prone students are presented in this publication. Data compiled on dropouts by the South Carolina State Department of Education indicate that approximately one out of every two first graders in South Carolina public schools drops out of school before completing the…

  2. 24 CFR 982.54 - Administrative plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... activity or alcohol abuse in accordance with § 982.553; (5) Encouraging participation by owners of suitable units located outside areas of low income or minority concentration; (6) Assisting a family that claims... redeterminations of family income and composition; (19) Restrictions, if any, on the number of moves by...

  3. 24 CFR 982.54 - Administrative plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... activity or alcohol abuse in accordance with § 982.553; (5) Encouraging participation by owners of suitable units located outside areas of low income or minority concentration; (6) Assisting a family that claims... redeterminations of family income and composition; (19) Restrictions, if any, on the number of moves by...

  4. Cash Flow Planning.

    ERIC Educational Resources Information Center

    Littman, George W., III

    1979-01-01

    Proper cash flow planning allows a school business administrator to determine the availability of cash for operating expenses, the need for bank loans to cover these expenses, and the availability of idle cash for investment. (Author)

  5. Administration's Plan to Eliminate Older Workers Jobs Program. Hearings before the Subcommittee on Retirement Income and Employment of the Select Committee on Aging. House of Representatives, Ninety-Seventh Congress, Second Session (Washington, DC, February 25, 1982; Boston, MA, February 19, 1982; Astoria, NY, February 22, 1982).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    The Subcommittee on Aging of the House of Representatives was provided with information on the administration's plan to eliminate the older workers jobs program authorized by Title V, Older Americans Act. Testimony for each hearing begins with opening statements by members of the subcommittee. Statements follow from approximately 40 witnesses and…

  6. Administrative Evaluation. Administrator's Update. Volume 1, Number 1.

    ERIC Educational Resources Information Center

    Winschel, Carolyn

    Literature relevant to administrative evaluation in higher education was surveyed. Reasons for the increasing importance of this type of evaluation, approaches to and components of an evaluation plan, some of the problems involved in the evaluation process, and use of results are discussed. The current literature indicates that increased presure…

  7. Leadership with Administration: Securing Administrative Support for Transforming Your Program

    ERIC Educational Resources Information Center

    Saginak, Kelli A.; Dollarhide, Colette T.

    2006-01-01

    This article provides school counselors with a plan for securing administrative support for implementing of comprehensive school counseling programs. Systems and systems theory is introduced to explain systemic change in the context of leadership. Leadership theory is presented to assist school counselors in leading systemic change and securing…

  8. Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer.

    PubMed

    Letessier, A; Garrido-Urbani, S; Ginestier, C; Fournier, G; Esterni, B; Monville, F; Adélaïde, J; Geneix, J; Xerri, L; Dubreuil, P; Viens, P; Charafe-Jauffret, E; Jacquemier, J; Birnbaum, D; Lopez, M; Chaffanet, M

    2007-01-11

    Common fragile sites (CFSs) are regions of chromosomal break that may play a role in oncogenesis. The most frequent alteration occurs at FRA3B, within the FHIT gene, at chromosomal region 3p14. We studied a series of breast carcinomas for break of a CFS at 6q26, FRA6E, and its associated gene PARK2, using fluorescence in situ hybridization on tissue microarrays (TMA). We found break of PARK2 in 6% of cases. We studied the PARK2-encoded protein Parkin by using immunohistochemistry on the same TMA. Loss of Parkin was found in 13% of samples but was not correlated with PARK2 break. PARK2 break but not Parkin expression was correlated with prognosis. Alteration of PARK2/FRA6E may cause haplo-insufficiency of one or several telomeric potential tumor suppressor genes (TSG). The AF-6/MLLT4 gene, telomeric of PARK2, encodes the Afadin scaffold protein, which is essential for epithelial integrity. Loss of Afadin was found in 14.5% of cases, and 36% of these cases showed PARK2 break. Loss of Afadin had prognostic impact, suggesting that AF-6 may be a TSG. Loss of Afadin was correlated with loss of FHIT expression, suggesting fragility of FRA6E and FRA3B in a certain proportion of breast tumors. PMID:16819513

  9. Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product.

    PubMed Central

    Vallone, D; Battista, S; Pierantoni, G M; Fedele, M; Casalino, L; Santoro, M; Viglietto, G; Fusco, A; Verde, P

    1997-01-01

    The expression of the high mobility group I (HMGI)-C chromatin component was shown previously to be essential for the establishment of the neoplastic phenotype in retrovirally transformed thyroid cell lines. To identify possible targets of the HMGI-C gene product, we have analyzed the AP-1 complex in normal, fully transformed and antisense HMGI-C-expressing rat thyroid cells. We show that neoplastic transformation is associated with a drastic increase in AP-1 activity, which reflects multiple compositional changes. The strongest effect is represented by the dramatic junB and fra-1 gene induction, which is prevented in cell lines expressing the antisense HMGI-C. These results indicate that the HMGI-C gene product is essential for the junB and fra-1 transcriptional induction associated with neoplastic transformation. The inhibition of Fra-1 protein synthesis by stable transfection with a fra-1 antisense RNA vector significantly reduces the malignant phenotype of the transformed thyroid cells, indicating a pivotal role for the fra-1 gene product in the process of cellular transformation. PMID:9311991

  10. Keys to Successful Systems Administration.

    ERIC Educational Resources Information Center

    Akins, M. L.; Griffin, J. R.

    1999-01-01

    Presents the main ingredients for successful computer-systems administration. Discusses training and ongoing support, change management for system upgrades, developing a problem-reporting form and keeping the documentation history, managing technical support, and having a disaster-recovery plan. (AEF)

  11. Improving Administrative Efficiency through Technology.

    ERIC Educational Resources Information Center

    Porter, Dennis R.

    1993-01-01

    Key adult education management functions (planning, directing personnel, organizing work, staffing, and evaluating) can be enhanced through appropriate technologies. Of particular interest to administrators are computer-based communications, management information systems, and desktop application software such as spreadsheets, groupware, and…

  12. Alleviating Stress for Women Administrators.

    ERIC Educational Resources Information Center

    Ten Elshof, Annette; Tomlinson, Elaine

    1981-01-01

    Describes a workshop designed to help women administrators assess individual stress levels. Stress can be alleviated through exercise, support groups or networking, sleep and diet, relaxation, guided fantasy, and planned activity. The long-term implications include preventing illness and making women more effective within the administrative…

  13. Vocational Planning Guide.

    ERIC Educational Resources Information Center

    Dyrenfurth, Michael J.; Elias, John E.

    This guide provides local vocational administrators (LVAs) with information and guidelines to plan vocational programs for their school, district, or community college. The first four chapters outline a four-step planning process. They guide the LVA through (1) establishment of vocational education's place within the community's educational…

  14. Planned Change in Education.

    ERIC Educational Resources Information Center

    Miller, Donald R.

    Educational planners and managers are provided with the background knowledge essential to understanding and effecting planned change in education. Several dimensions of planned change are outlined and related to involvement of administrators, operational leaders, and teachers. Also presented is a model of the time-involvement dimensions for…

  15. 7. Administrative structures.

    PubMed

    2014-05-01

    The basic systems of any society rarely can operate independently. Instead, they are dependent and often interdependent upon other entities. Such entities control the resources within their respective systems. Thus, coordination and control agencies require contracts or memoranda of understanding with these entities in order to assure access to the resources required during a crisis. These administrative structures include: (1) governmental institutions and agencies, including the military; (2) intergovernmental organisations; (3) nongovernmental organisations; (4) commercial private sector organisations; and (5) academic institutions. These dependencies create potential barriers to the provision of coordination and control including: (1) the complexity of the administrative structures with which coordination and control must interact; (2) the location of resources; (3) finding responsible person(s); (4) the competence and compatibility; (5) methods of access; (6) payment; (7) contracts and memoranda of understanding; (8) inventories of accessible resources; (9) competition for the mandate, power, and resources; and (10) jealousy. The need for potential interactions between administrative structures requires that agreements for the sharing of resources during crises be reached as part of planning and preparedness. Gaining an understanding of these relationships is an important area for research. PMID:24785804

  16. Planning for an Enrollment Drop!

    ERIC Educational Resources Information Center

    Blaustein, M. Lee

    Faced with the prospect of declining school enrollment, educational administrators must take stock of the situation and outline plans for improving the quality of education in a period of reduced enrollment and possibly reduced state aid to local school districts. Planning principles that can help administrators in this task include the following:…

  17. Copy number and haplotype variation at the VRN-A1 and central FR-A2 loci are associated with frost tolerance in hexaploid wheat

    PubMed Central

    Zhu, Jie; Pearce, Stephen; Burke, Adrienne; See, Deven Robert; Skinner, Daniel Z.; Dubcovsky, Jorge; Campbell, Kimberly Garland

    2016-01-01

    Frost tolerance is critical for wheat survival during cold winters. Natural variation for this trait is mainly associated with allelic differences at the VERNALIZATION 1 (VRN1) and FROST RESISTANCE 2 (FR2) loci. VRN1 regulates the transition between vegetative and reproductive stages and FR2, a locus including several tandemly duplicated C-REPEAT BINDING FACTOR (CBF) transcription factors, regulates the expression of Cold regulated genes. We identified sequence and copy number variation at these two loci among winter and spring wheat varieties and characterized their association with frost tolerance. We identified two FR-A2 haplotypes – ‘FR-A2-S’ and ‘FR-A2-T’ – distinguished by two insertion/deletions and ten single nucleotide polymorphisms within the CBF-A12 and CBF-A15 genes. Increased copy number of CBF-A14 was frequently associated with the FR-A2-T haplotypes and with higher CBF14 transcript levels in response to cold. Factorial ANOVAs revealed significant interactions between VRN1 and FR-A2 for frost tolerance in both winter and spring panels suggesting a crosstalk between vernalization and cold acclimation pathways. The model including these two loci and their interaction explained 32.0 and 20.7% of the variation in frost tolerance in the winter and spring panels, respectively. The interaction was validated in a winter wheat F4:5 population segregating for both genes. Increased VRN-A1 copy number was associated with improved frost tolerance among varieties carrying the FR-A2-T allele but not among those carrying the FR-A2-S allele. These results suggest that selection of varieties carrying the FR-A2-T allele and three copies of the recessive vrn-A1 allele would be a good strategy to improve frost tolerance in wheat. PMID:24626953

  18. 78 FR 54949 - Major Project Financial Plan Guidance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... TRANSPORTATION Federal Highway Administration Major Project Financial Plan Guidance AGENCY: Federal Highway... Major Project Financial Plan Guidance outlining the procedures the FHWA will follow when reviewing and approving Financial Plans. The proposed Major Project Financial Plan Guidance incorporates changes...

  19. MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability.

    PubMed

    Cuevas, Bruce D; Uhlik, Mark T; Garrington, Timothy P; Johnson, Gary L

    2005-01-27

    Activator protein 1 (AP-1) transcription factor dimers are composed of Jun, Fos, and ATF member proteins, but the mechanisms that determine AP-1 composition are not clearly defined and the function of specific dimers is not well understood. MEKK1 is a mitogen-activated protein kinase (MAPK) kinase kinase and an ubiquitin ligase that regulates both the extracellular signal-regulated kinase 1/2 and the c-Jun amino-terminal kinase. Herein, we demonstrate that MEKK1 regulates the AP-1 protein repertoire. Both FGF-2 and phorbol ester-inducible urokinase-type plasminogen activator (uPA) expression requires AP-1 binding to an enhancer element in the uPA promoter, and we have previously shown that FGF-2 or PMA induction of uPA expression is strongly dependent on MEKK1. JunB mRNA is significantly increased in MEKK1-/- cells, demonstrating that MEKK1 suppresses JunB mRNA expression. Upregulation of JunB expression in MEKK1-/- cells forms an inhibitory AP-1 complex that binds to the uPA promoter and inhibits uPA transcription. MEKK1 also regulates Fra-2 protein stability by inducing Fra-2 ubiquitination and degradation. MEKK1 regulates AP-1-dependent gene expression by regulating the expression, activity and degradation of component members of the AP-1 complex. Controlling the repertoire of a transcription factor complex is a newly defined function for an MAPK kinase kinase. PMID:15558021

  20. WWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancer.

    PubMed

    Richards, Robert I; Choo, Amanda; Lee, Cheng Shoou; Dayan, Sonia; O'Keefe, Louise

    2015-03-01

    The WWOX gene spans the common chromosomal fragile site FRA16D that is located within a massive (780 kb) intron. The WWOX gene is very long, at 1.1 Mb, which may contribute to the very low abundance of the full-length 1.4 kb mRNA. Alternative splicing also accounts for a variety of aberrant transcripts, most of which are devoid of C-terminal sequences required for WWOX to act as an oxidoreductase. The mouse WWOX gene also spans a chromosomal fragile site implying some sort of functional relationship that confers a selective advantage. The encoded protein domains of WWOX are conserved through evolution (between humans and Drosophila melanogaster) and include WW domains, an NAD -binding site, short-chain dehydrogenase/reductase enzyme and nuclear compartmentalization signals. This homology has enabled functional analyses in D. melanogaster that demonstrate roles for WWOX in reactive oxygen species regulation and metabolism. Indeed the human WWOX gene is also responsive to altered metabolism. Cancer cells typically exhibit altered metabolism (Warburg effect). Many cancers exhibit FRA16D DNA instability that results in aberrant WWOX expression and is associated with poor prognosis for these cancers. It is therefore thought that aberrant WWOX expression contributes to the altered metabolism in cancer. In addition, others have found that a specific (low-expression) allele of WWOX genotype contributes to cancer predisposition. PMID:25595186

  1. 49 CFR 601.4 - Responsibilities of the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 7 2013-10-01 2013-10-01 false Responsibilities of the Administrator. 601.4... Responsibilities of the Administrator. The Administrator is responsible for the planning, direction and control of... Deputy Administrator is the “first assistant” for purposes of the Federal Vacancies Reform Act of...

  2. 49 CFR 601.4 - Responsibilities of the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 7 2012-10-01 2012-10-01 false Responsibilities of the Administrator. 601.4... Responsibilities of the Administrator. The Administrator is responsible for the planning, direction and control of... Deputy Administrator is the “first assistant” for purposes of the Federal Vacancies Reform Act of...

  3. 49 CFR 601.4 - Responsibilities of the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Responsibilities of the Administrator. 601.4... Responsibilities of the Administrator. The Administrator is responsible for the planning, direction and control of... Deputy Administrator is the “first assistant” for purposes of the Federal Vacancies Reform Act of...

  4. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development...

  5. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development...

  6. 7 CFR 23.10 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Administration. 23.10 Section 23.10 Agriculture Office of the Secretary of Agriculture STATE AND REGIONAL ANNUAL PLANS OF WORK Regional Program § 23.10 Administration. (a) The Regional Programs will be administered through four Regional Rural Development...

  7. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  8. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Administrative costs. 96.88 Section 96.88 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of...

  9. 40 CFR 209.10 - Approval of plan, implementation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Approval of plan, implementation. 209... Approval of plan, implementation. (a) If the Administrator finds that the remedial plan is designed to... implementation of the approved plan upon receipt of notice from the Administrator that the remedial plan has...

  10. Strategic Planning for Collegiate Athletics.

    ERIC Educational Resources Information Center

    Yow, Deborah A.; Migliore, R. Henry; Bowden, William W.; Stevens, Robert E.; Loudon, David L.

    This book presents strategies for planning and managing athletic programs. It helps college athletic administrators analyze their organization's environment, set objectives, decide on specific actions, and obtain feedback. Chapter 1, "Perspectives on Planning for Athletics Programs," discusses what planning is and why it is important. Chapter 2,…

  11. Strengthening State Library Administrative Agency (Territorial Library).

    ERIC Educational Resources Information Center

    Nieves M. Flores Memorial Library, Agana, Guam.

    This document describes the Basic State Plan Amendments for the Library Services and Construction Act in Guam and the regulations promulgated thereunder. The major projects described under the plan are: Strengthening State Library Administrative Agency; Staff Development; Library Collections, Extention Services, Institutional Libraries; and…

  12. 21 CFR 812.25 - Investigational plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Investigational plan. 812.25 Section 812.25 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.25 Investigational plan. The investigational plan shall...

  13. 5 CFR 370.109 - Agency plans.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Agency plans. 370.109 Section 370.109 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS INFORMATION TECHNOLOGY EXCHANGE... under this part, an agency must establish an Information Technology Exchange Program Plan. The plan...

  14. 21 CFR 812.25 - Investigational plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Investigational plan. 812.25 Section 812.25 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.25 Investigational plan. The investigational plan shall...

  15. 45 CFR 95.507 - Plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Plan requirements. 95.507 Section 95.507 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GENERAL ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Cost Allocation Plans § 95.507 Plan requirements....

  16. Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer

    PubMed Central

    Gupta, Shilpi; Kumar, Prabhat; Kaur, Harsimrut; Sharma, Nishi; Saluja, Daman; Bharti, Alok C.; Das, Bhudev C.

    2015-01-01

    Tongue squamous cell carcinoma (TSCC) is most aggressive head and neck cancer often associated with HR-HPV infection. The role of AP-1 which is an essential regulator of HPV oncogene expression and tumorigenesis is not reported in tongue cancer. One hundred tongue tissue biopsies comprising precancer, cancer and adjacent controls including two tongue cancer cell lines were employed to study the role of HPV infection and AP-1 family proteins. An exclusive prevalence (28%) of HR-HPV type 16 was observed mainly in well differentiated tongue carcinomas (78.5%). A higher expression and DNA binding activity of AP-1 was observed in tongue tumors and cancer cell lines with c-Fos and Fra-2 as the major binding partners forming the functional AP-1 complex but c-Jun participated only in HPV negative and poorly differentiated carcinoma. Knocking down of Fra-2 responsible for aggressive tongue tumorigenesis led to significant reduction in c-Fos, c-Jun, MMP-9 and HPVE6/E7 expression but Fra-1 and p53 were upregulated. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis only in HPV negative cases while HPV infection leads to well differentiation and better prognosis preferably in nonsmokers. PMID:26581505

  17. 49 CFR 242.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF CONDUCTORS Program and Eligibility Requirements § 242.103 Approval of design of individual railroad...

  18. 49 CFR 242.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF CONDUCTORS Program and Eligibility Requirements § 242.103 Approval of design of individual railroad...

  19. 49 CFR 242.103 - Approval of design of individual railroad programs by FRA.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Approval of design of individual railroad programs... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF CONDUCTORS Program and Eligibility Requirements § 242.103 Approval of design of individual railroad...

  20. Senior Administrators Should Have Administrative Contracts.

    ERIC Educational Resources Information Center

    Posner, Gary J.

    1987-01-01

    Recognizing that termination is viewed by the employee as the equivalent to capital punishment of a career, an administrative contract can reduce the emotional and financial entanglements that often result. Administrative contracts are described. (MLW)

  1. [Biological and physico-chemical properties of Yersinia pseudotuberculosis bacterial culture having the fra-operon Yersinia pestis].

    PubMed

    Byvalov, A A; Gavrilov, K E; Krupin, V V; Chebotarev, E V; Zheludkova, E V; Drubkov, V I; Smirnov, A E; Mal'kov, V N; Dupiasheva, T Iu; Pechenkin, D V; Bondarev, V P

    2008-01-01

    The biological and physico-chemical properties of cultures of two isogenous recombinant variants of Yersinia pseudotuberculosis were studied. The cell genomes of the cultures are distinguished from one another only by the presence or by the absence of the fra-operon, which is a determined attribute of the plague microbe capsule-forming process. The expression of the attribute is amplified by rising the microbial biomass cultivation temperature and stimulates the decrease in the viability of the bacteria and adaptation potential in vitro. In the warm-blooded owner organism the microbes of the capsule-forming recombinant variant are characterized by the greater residual pathogenicity and immunogenic ability to the experimental plague of the laboratory animals as compared to the reference-variant cells. These specific features could be explained by more expressed colonizing ability of the capsule-forming microbes provided by owner cells' stability to the phagocyte process. PMID:18368776

  2. In quest of lunar regolith breccias of exotic provenance - A uniquely anorthositic sample from the Fra Mauro (Apollo 14) highlands

    NASA Technical Reports Server (NTRS)

    Jerde, Eric A.; Warren, Paul H.; Morris, Richard V.

    1990-01-01

    Bulk compositions of 21 Apollo regolith breccias were determined using an INAA procedure modified from that of Kallemeyn et al. (1989). With one major exception, namely, the 14076,1 sample, the regolith breccias analyzed were found to be not significantly different from the surfaces from which they were collected. In contrast, the 14076,1 sample from the Fra Mauro (Apollo 14) region is a highly anorthositic regolith breccia from a site where anorthosites are extremely scarce. The sample's composition resembles soils from the Descartes (Apollo 16) highlands. However, the low statistical probability for long-distance horizontal transport by impact cratering, together with the relatively high contents of imcompatible elements in 14076,1 suggest that this regolith breccia originated within a few hundred kilometers of the Apollo 14 site. Its compositional resemblance to ferroan anorthosite strengthens the hypothesis that ferroan anorthosite originated as the flotation crust of a global magmasphere.

  3. WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response

    PubMed Central

    Abu-Odeh, Mohammad; Salah, Zaidoun; Herbel, Christoph; Hofmann, Thomas G.; Aqeilan, Rami I.

    2014-01-01

    Genomic instability is a hallmark of cancer. The WW domain-containing oxidoreductase (WWOX) is a tumor suppressor spanning the common chromosomal fragile site FRA16D. Here, we report a direct role of WWOX in DNA damage response (DDR) and DNA repair. We show that Wwox deficiency results in reduced activation of the ataxia telangiectasia-mutated (ATM) checkpoint kinase, inefficient induction and maintenance of γ-H2AX foci, and impaired DNA repair. Mechanistically, we show that, upon DNA damage, WWOX accumulates in the cell nucleus, where it interacts with ATM and enhances its activation. Nuclear accumulation of WWOX is regulated by its K63-linked ubiquitination at lysine residue 274, which is mediated by the E3 ubiquitin ligase ITCH. These findings identify a novel role for the tumor suppressor WWOX and show that loss of WWOX expression may drive genomic instability and provide an advantage for clonal expansion of neoplastic cells. PMID:25331887

  4. Insulin-stimulated expression of c-fos, fra1 and c-jun accompanies the activation of the activator protein-1 (AP-1) transcriptional complex.

    PubMed Central

    Griffiths, M R; Black, E J; Culbert, A A; Dickens, M; Shaw, P E; Gillespie, D A; Tavaré, J M

    1998-01-01

    The activator protein-1 (AP-1) transcriptional complex is made up of members of the Fos (c-Fos, FosB, Fra1, Fra2) and Jun (c-Jun, JunB, JunD) families and is stimulated by insulin in several cell types. The mechanism by which insulin activates this complex is not well understood but it is dependent on the activation of the Erk1 and Erk2 isoforms of mitogen-activated protein kinases. In the current study we show that the AP-1 complex isolated from insulin-stimulated cells contained c-Fos, Fra1, c-Jun and JunB. The activation of the AP-1 complex by insulin was accompanied by (i) a transient increase in c-fos expression, and the transactivation of the ternary complex factors Elk1 and Sap1a, in an Erk1/Erk2-dependent fashion; (ii) a substantial increase in the expression of Fra1 protein and mRNA, which was preceded by a transient decrease in its electrophoretic mobility upon SDS/PAGE, indicative of phosphorylation; and (iii) a sustained increase in c-jun expression without increasing c-Jun phosphorylation on serines 63 and 73 or activation of the stress-activated kinase JNK/SAPK. In conclusion, insulin appears to stimulate the activity of the AP-1 complex primarily through a change in the abundance of the components of this complex, although there may be an additional role for Fra1 phosphorylation. PMID:9742208

  5. HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells

    PubMed Central

    Tang, Xiaomei; Xia, Yong; He, Guozhen; Min, Zhiqun; Li, Chun; Xiong, Shiqiu; Shi, Zhi; Lu, Yongjian; Yuan, Zhongmin

    2016-01-01

    Activator protein 1 (AP-1) is a transcriptional factor composed of the dimeric members of bZIP proteins, which are frequently deregulated in human cancer cells. In this study, we aimed to identify an oncogenic AP-1 dimer critical for the proliferation of neuroblastoma cells and to investigate whether histone deacetylase inhibitors (HDACIs), a new generation of anticancer agents, could target the AP-1 dimer. We report here that HDACIs including trichostatin A, suberoylanilidehydroxamic acid, valproic acid and M344 can transcriptionally suppress both c-Jun and Fra-1, preceding their inhibition of cell growth. c-Jun preferentially interacting with Fra-1 as a heterodimer is responsible for AP-1 activity and critical for cell growth. Mechanistically, HDACIs suppress Fra-1 expression through transcriptionally downregulating Raf1 and subsequently decreasing MEK1/2-ERK1/2 activity. Unexpectedly, HDACI treatment caused MKK7 downregulation at both the protein and mRNA levels. Deletion analysis of the 5′-flanking sequence of the MKK7 gene revealed that a major element responsible for the downregulation by HDACI is located at −149 to −3 relative to the transcriptional start site. Knockdown of MKK7 but not MKK4 remarkably decreased JNK/c-Jun activity and proliferation, whereas ectopic MKK7-JNK1 reversed HDACI-induced c-Jun suppression. Furthermore, suppression of both MKK-7/c-Jun and Raf-1/Fra-1 activities was involved in the tumor growth inhibitory effects induced by SAHA in SH-SY5Y xenograft mice. Collectively, these findings demonstrated that c-Jun/Fra-1 dimer is critical for neuroblastoma cell growth and that HDACIs act as effective suppressors of the two oncogenes through transcriptionally downregulating MKK7 and Raf1. PMID:26734995

  6. A comparison of forest cover maps in Mainland Southeast Asia from multiple sources: PALSAR, MERIS, MODIS and FRA

    NASA Astrophysics Data System (ADS)

    Dong, J.; Xiao, X.; Sheldon, S. L.; Biradar, C. M.; Duong, N. D.; Hazarika, M.

    2012-12-01

    The uncertainty in tracking tropical forest extent and changes substantially affects our assessment of the consequences of forest change on the global carbon cycle, biodiversity and ecosystem services. Recently cloud-free imagery useful for tropical forest mapping from the Phased Array Type L-band Synthetic Aperture Radar (PALSAR) onboard the Advanced Land Observing Satellite (ALOS) has become available. We used PALSAR 50-m Orthorectified mosaic imagery in 2009 and a decision tree method to conduct land cover classification and generate a 2009 forest map, which was evaluated using 2106 field photos from the Global Geo-referenced Field Photo Library (http://www.eomf.ou.edu/photos). The resulting land cover classification had a high overall accuracy of 93.3 % and a Kappa Coefficient of 0.9. The PALSAR-based forest map was then compared with three existing forest cover products at three scales (regional, national, and continental): the Food and Agriculture Organization of the United Nations (FAO) Forest Resources Assessments (FRA) 2010, Global Land Cover Map with MERIS (GlobCover) 2009, and the MODIS Terra + Aqua Land Cover Type product (MCD12Q1) 2009. The intercomparison results show that these four forest datasets differ. The PALSAR-based forest area estimate is within the range (6.1 ~ 9.0 ×105 km2) of the other three products and closest to the FAO FRA 2010 estimate. The spatial disagreements of the PALSAR-based forest, MCD12Q1 forest and GlobCover forest are evident; however, the PALSAR-based forest map provides more detail (50-m spatial resolution) and high accuracy (the Producer's and the User's Accuracies were 88 % and 95 %, respectively) and PALSAR can be used to evaluate MCD12Q1 2009 and GlobCover 2009 forest maps. Given the higher spatial resolution, PALSAR-based forest products could further improve the modeling accuracy of carbon cycle in tropical forests.

  7. Novice Administrators: Personality and Administrative Style Changes.

    ERIC Educational Resources Information Center

    Schmidt, Linda J.; Kosmoski, Georgia J.; Pollack, Dennis R.

    Since the advent of effective-schools research findings, educational administration experts have advocated a democratic and collegial leadership style for school administrators. This paper provides the findings of a study that examined 43 beginning administrators (25 females, 32 Caucasians, 9 African-Americans, 2 Hispanics) to determine what…

  8. 42 CFR 431.702 - State plan requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Licensing Nursing Home Administrators § 431.702 State plan requirement. A State plan must provide that the State has a program for licensing administrators of nursing homes that meets the requirements of §§...

  9. 42 CFR 431.702 - State plan requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Licensing Nursing Home Administrators § 431.702 State plan requirement. A State plan must provide that the State has a program for licensing administrators of nursing homes that meets the requirements of §§...

  10. 42 CFR 431.702 - State plan requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Licensing Nursing Home Administrators § 431.702 State plan requirement. A State plan must provide that the State has a program for licensing administrators of nursing homes that meets the requirements of §§...

  11. 42 CFR 431.702 - State plan requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Licensing Nursing Home Administrators § 431.702 State plan requirement. A State plan must provide that the State has a program for licensing administrators of nursing homes that meets the requirements of §§...

  12. Guidelines for Planning in Colleges and Universities. Volume One, Planning System.

    ERIC Educational Resources Information Center

    Pinnell, Charles; Wacholder, Michael

    This volume outlines a system for effective planning in higher education. The system integrates management and program planning, physical plant planning, and financial planning into a single process designed to support institutional management and decision making at all administrative levels. Because successful planning is a process, procedures…

  13. 75 FR 64389 - Proposed Recommendation to the Social Security Administration for Occupational Information System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ... From the Federal Register Online via the Government Publishing Office ] SOCIAL SECURITY ADMINISTRATION Proposed Recommendation to the Social Security Administration for Occupational Information System (OIS) Development Planning; Request for Comment AGENCY: Social Security Administration. ACTION:...

  14. 49 CFR 244.1 - Scope, application, and purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... approval by the Surface Transportation Board. See 49 CFR part 1106. ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD... part prescribes requirements for filing and implementing a Safety Integration Plan with FRA whenever...

  15. 49 CFR 244.1 - Scope, application, and purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... approval by the Surface Transportation Board. See 49 CFR part 1106. ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD... part prescribes requirements for filing and implementing a Safety Integration Plan with FRA whenever...

  16. 49 CFR 244.1 - Scope, application, and purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... approval by the Surface Transportation Board. See 49 CFR part 1106. ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD... part prescribes requirements for filing and implementing a Safety Integration Plan with FRA whenever...

  17. 49 CFR 244.1 - Scope, application, and purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... approval by the Surface Transportation Board. See 49 CFR part 1106. ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD... part prescribes requirements for filing and implementing a Safety Integration Plan with FRA whenever...

  18. 49 CFR 244.1 - Scope, application, and purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... approval by the Surface Transportation Board. See 49 CFR part 1106. ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD... part prescribes requirements for filing and implementing a Safety Integration Plan with FRA whenever...

  19. FY 2016 - Stockpile Stewardship and Management Plan

    SciTech Connect

    2015-03-01

    This Department of Energy’s (DOE) National Nuclear Security Administration (NNSA) Fiscal Year Stockpile Stewardship and Management Plan (SSMP) is a key planning document for the nuclear security enterprise.

  20. FY 2015 - Stockpile Stewardship and Management Plan

    SciTech Connect

    2014-04-01

    This Department of Energy’s (DOE) National Nuclear Security Administration (NNSA) Fiscal Year Stockpile Stewardship and Management Plan (SSMP) is a key planning document for the nuclear security enterprise.

  1. Succession Management: A Necessary Strategy for Rural School Administration.

    ERIC Educational Resources Information Center

    Wallin, Dawn C.

    This paper discusses succession planning for rural educational administrators, focusing on management succession practices, responsibilities, and policies that ensure the efficient and effective transition of rural administrators. In planning their human resources, all organizations must match the needs of the organization with the shifting needs…

  2. 45 CFR 301.10 - State plan.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false State plan. 301.10 Section 301.10 Public Welfare...), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES STATE PLAN APPROVAL AND GRANT PROCEDURES § 301.10 State plan. The State plan is a comprehensive statement submitted by the IV-D...

  3. 15 CFR 8a.230 - Transition plans.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Transition plans. 8a.230 Section 8a... Transition plans. (a) Submission of plans. An institution to which § 8a.225 applies and that is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  4. 45 CFR 86.17 - Transition plans.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Transition plans. 86.17 Section 86.17 Public... Transition plans. (a) Submission of plans. An institution to which § 86.16 applies and which is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  5. 5 CFR 370.109 - Agency plans.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Agency plans. 370.109 Section 370.109... PROGRAM § 370.109 Agency plans. Before detailing agency employees or receiving private sector employees under this part, an agency must establish an Information Technology Exchange Program Plan. The plan...

  6. 45 CFR 301.10 - State plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false State plan. 301.10 Section 301.10 Public Welfare...), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES STATE PLAN APPROVAL AND GRANT PROCEDURES § 301.10 State plan. The State plan is a comprehensive statement submitted by the IV-D...

  7. 23 CFR 1335.6 - Strategic plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Strategic plan. 1335.6 Section 1335.6 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STATE HIGHWAY SAFETY DATA IMPROVEMENTS § 1335.6 Strategic plan. A strategic plan shall— (a) Be a multi-year plan that identifies and...

  8. 5 CFR 720.304 - Agency plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Agency plan. 720.304 Section 720.304...) AFFIRMATIVE EMPLOYMENT PROGRAMS Disabled Veterans Affirmative Action Program § 720.304 Agency plan. (a) Plan Development. As part of the affirmative action plan it prepares pursuant to section 501(b) of...

  9. 5 CFR 370.109 - Agency plans.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Agency plans. 370.109 Section 370.109... PROGRAM § 370.109 Agency plans. Before detailing agency employees or receiving private sector employees under this part, an agency must establish an Information Technology Exchange Program Plan. The plan...

  10. 31 CFR 28.230 - Transition plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Transition plans. 28.230 Section 28... Transition plans. (a) Submission of plans. An institution to which § 28.225 applies and that is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  11. 15 CFR 8a.230 - Transition plans.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Transition plans. 8a.230 Section 8a... Transition plans. (a) Submission of plans. An institution to which § 8a.225 applies and that is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  12. 45 CFR 86.17 - Transition plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Transition plans. 86.17 Section 86.17 Public... Transition plans. (a) Submission of plans. An institution to which § 86.16 applies and which is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  13. 31 CFR 28.230 - Transition plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Transition plans. 28.230 Section 28... Transition plans. (a) Submission of plans. An institution to which § 28.225 applies and that is composed of more than one administratively separate unit may submit either a single transition plan applicable...

  14. 5 CFR 720.304 - Agency plan.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Agency plan. 720.304 Section 720.304...) AFFIRMATIVE EMPLOYMENT PROGRAMS Disabled Veterans Affirmative Action Program § 720.304 Agency plan. (a) Plan Development. As part of the affirmative action plan it prepares pursuant to section 501(b) of...

  15. 23 CFR 1335.6 - Strategic plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Strategic plan. 1335.6 Section 1335.6 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STATE HIGHWAY SAFETY DATA IMPROVEMENTS § 1335.6 Strategic plan. A strategic plan shall— (a) Be a multi-year plan that identifies and...

  16. 23 CFR 1335.6 - Strategic plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Strategic plan. 1335.6 Section 1335.6 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STATE HIGHWAY SAFETY DATA IMPROVEMENTS § 1335.6 Strategic plan. A strategic plan shall— (a) Be a multi-year plan that identifies and...

  17. 24 CFR 3282.302 - State plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false State plan. 3282.302 Section 3282... State plan. A State wishing to qualify and act as an SAA under this subpart shall make a State Plan Application under this section. The State Plan Application shall be made to the Administrator, Office...

  18. 44 CFR 10.7 - Planning.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Planning. 10.7 Section 10.7... GENERAL ENVIRONMENTAL CONSIDERATIONS Agency Implementing Procedures § 10.7 Planning. (a) Early planning. The Regional Administrator shall integrate the NEPA process with other planning at the...

  19. 40 CFR 35.107 - Work plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Work plans. 35.107 Section 35.107... ASSISTANCE Environmental Program Grants Preparing An Application § 35.107 Work plans. (a) Bases for negotiating work plans. The work plan is negotiated between the applicant and the Regional Administrator...

  20. 40 CFR 35.107 - Work plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Work plans. 35.107 Section 35.107... ASSISTANCE Environmental Program Grants Preparing An Application § 35.107 Work plans. (a) Bases for negotiating work plans. The work plan is negotiated between the applicant and the Regional Administrator...

  1. 40 CFR 35.107 - Work plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Work plans. 35.107 Section 35.107... ASSISTANCE Environmental Program Grants Preparing An Application § 35.107 Work plans. (a) Bases for negotiating work plans. The work plan is negotiated between the applicant and the Regional Administrator...

  2. 40 CFR 35.107 - Work plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Work plans. 35.107 Section 35.107... ASSISTANCE Environmental Program Grants Preparing An Application § 35.107 Work plans. (a) Bases for negotiating work plans. The work plan is negotiated between the applicant and the Regional Administrator...

  3. 40 CFR 35.107 - Work plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Work plans. 35.107 Section 35.107... ASSISTANCE Environmental Program Grants Preparing An Application § 35.107 Work plans. (a) Bases for negotiating work plans. The work plan is negotiated between the applicant and the Regional Administrator...

  4. Working toward Independence: The Administration's Plan To Build upon the Successes of Welfare Reform. Hearing before the Committee on Education and the Workforce. House of Representatives, One Hundred Seventh Congress, Second Session (April 9, 2002).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and the Workforce.

    This document reports on a congressional hearing on the George W. Bush administration's proposals for welfare reform and legislation to reauthorize the 1996 welfare reform law. Testimony includes statements from United States (US) Representatives John Boehner and Patsy Mink; Tommy G. Thompson, Secretary of the U.S. Department of Health and Human…

  5. Financial Management and Strategic Planning.

    ERIC Educational Resources Information Center

    Dickmeyer, Nathan

    1982-01-01

    Strategic planning involves analysis of risks and opportunities; financial management entails balancing risks and resources to achieve institutional goals. A framework is suggested to help college administrators integrate the two functions. (Author/MSE)

  6. Organization/Administration.

    ERIC Educational Resources Information Center

    Chaffee, Ellen Earle

    Patterns that emerged from reviewing 26 syllabi for courses on organization and administration in higher education are discussed, and six sample syllabi are presented. The syllabi focused more on organization than administration. Of the 26 syllabi, 19 dealt with organization and administration generally; 5 with administration in a specific…

  7. Do You Need a New Campus Master Plan?

    ERIC Educational Resources Information Center

    Sturgeon, Julie

    1999-01-01

    Explains why school administrators should review their campus Master Plans every five to 10 years, and highlights guidelines for developing a Master Plan. Three examples are provided of how school administrators succeeded in developing their campus Master Plans as are suggested tips for Master Plan development that can guarantee positive outcomes.…

  8. 13 CFR 303.5 - Eligible administrative expenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Eligible administrative expenses. 303.5 Section 303.5 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF... administrative expenses. In accordance with applicable Federal cost principles, Planning Investments may be...

  9. 13 CFR 303.5 - Eligible administrative expenses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Eligible administrative expenses. 303.5 Section 303.5 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF... administrative expenses. In accordance with applicable Federal cost principles, Planning Investments may be...

  10. 42 CFR 431.15 - Methods of administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Methods of administration. 431.15 Section 431.15 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 431.15 Methods of administration. A State plan must provide for methods of administration that...

  11. 42 CFR 423.666 - Review by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Review by the Administrator. 423.666 Section 423... and Appeals § 423.666 Review by the Administrator. (a) Request for review by Administrator. CMS or a Part D plan sponsor that has received a hearing decision may request a review by the...

  12. 42 CFR 423.666 - Review by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Review by the Administrator. 423.666 Section 423... and Appeals § 423.666 Review by the Administrator. (a) Request for review by Administrator. CMS or a Part D plan sponsor that has received a hearing decision may request a review by the...

  13. 42 CFR 423.666 - Review by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Review by the Administrator. 423.666 Section 423... Determinations and Appeals § 423.666 Review by the Administrator. (a) Request for review by Administrator. CMS or a Part D plan sponsor that has received a hearing decision may request a review by the...

  14. 42 CFR 423.666 - Review by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Review by the Administrator. 423.666 Section 423... Determinations and Appeals § 423.666 Review by the Administrator. (a) Request for review by Administrator. CMS or a Part D plan sponsor that has received a hearing decision may request a review by the...

  15. 42 CFR 431.15 - Methods of administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Methods of administration. 431.15 Section 431.15 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 431.15 Methods of administration. A State plan must provide for methods of administration that...

  16. 42 CFR 431.15 - Methods of administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Methods of administration. 431.15 Section 431.15 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 431.15 Methods of administration. A State plan must provide for methods of administration that...

  17. 34 CFR 361.12 - Methods of administration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Methods of administration. 361.12 Section 361.12... State Plan and Other Requirements for Vocational Rehabilitation Services Administration § 361.12 Methods... applicable, employs methods of administration found necessary by the Secretary for the proper and...

  18. 45 CFR 205.101 - Organization for administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Organization for administration. 205.101 Section... ADMINISTRATION-PUBLIC ASSISTANCE PROGRAMS § 205.101 Organization for administration. (a) A State plan for... description of the organization and functions of the single State agency and an organizational chart of...

  19. Mental retardation, acromegalic face, and megalotestes in two half-brothers: a specific form of X-linked mental retardation without fra(X) (q)?

    PubMed

    Tariverdian, G; Froster-Iskenius, U; Deuschl, G; Wolff, G

    1991-01-01

    We describe a family with two half-brothers affected with severe mental retardation. The phenotype in the affected individuals is characterized by apparent acromegaly, profound mental retardation, and hyperactivity. The mother has analogous but less severe facial anomalies and mild mental impairment. Screening for fra(X) (q) was negative in peripheral lymphocytes using methotrexate for fra(X) enhancement. The clinical findings in our patients are similar to those described by Fryns et al. [1986] in two patients with acquired lesions of the central nervous system. CT investigations in one of our patients showed areas of hyperdensity in the pontine region and a small subarachnoid cyst. The pedigree suggests X-linked inheritance. The association of apparent acromegaly, CNS anomalies, megalotestes, and mental retardation in this family supports the hypothesis that a distinct syndrome may exist with phenotype anomalies more severe than those characteristic for the Martin-Bell syndrome but without fragile X. PMID:2018059

  20. Planning Makes College Possible.

    ERIC Educational Resources Information Center

    Belmont, Jean

    Written by a college financial aid administrator, this booklet is intended to help parents of younger children plan and prepare for the financial aspects of college education. After an introductory chapter, Chapter II lists current and projected (year 2000) costs at the most expensive colleges and at New York City colleges. Chapter III presents…

  1. What Is Educational Planning? Fundamentals of Educational Planning-1.

    ERIC Educational Resources Information Center

    Coombs, Philip H.

    This report is one of a series primarily intended for those engaged in or preparing for educational planning and administration--especially in developing countries--as well as for those government officials and civic leaders seeking a more general understanding of educational planning and its role in overall national development. This booklet…

  2. Sources of clasts in terrestrial impact melts - Clues to the origin of LKFM. [Low-K Fra Mauro

    NASA Technical Reports Server (NTRS)

    Mccormick, K. A.; Taylor, G. J.; Keil, K.; Spudis, P. D.; Grieve, R. A. F.

    1989-01-01

    Low-K Fra Mauro (LKFM) 'basalt', which is found exclusively as an impact melt rock, cannot be modeled geochemically from its clast population or from any combination of known pristine lunar rock types. To clarify clast/melt relationships, a study was made of impact melt rocks from Mistastin Lake crater, Labrador, where there are only three target rocks: anorthosite, quartz monzonite, and granodiorite. Feldspar compositions in these rocks define distinct fields on the An-Ab-Or ternary diagram, making it possible to identify the source of each feldspar clast. Clasts in the Mistastin impact melts do not reflect the abundance of target rocks melted during the impact. The abundance of anorthosite in the clast population varies from 34 to 100 percent compared to a relatively constant value of 65 percent calculated to be in the melt matrix. Therefore the clasts appear to be derived predominantly from material relatively far removed from the zone of impact melting. Melt-matrix composition is dictated strictly by the composition of the target materials within a small radius around and below the point of impact. This suggests that the LKFM composition was derived from a lower crustal source.

  3. Transcriptional profiling of genes at the human common fragile site FRA1H in tumor-derived cell lines.

    PubMed

    Pelliccia, Franca; Curatolo, Angela; Limongi, Zaira M; Bosco, Nazario; Rocchi, Angela

    2007-10-15

    Common fragile sites (CFSs) are chromosome regions that exhibit gaps and breaks when the cells are exposed to replication stress and to some DNA-binding compounds. In cancer cells, the CFSs are frequently involved in recurrent chromosome rearrangements. Furthermore, altered expression of associated genes, known or potential oncogenes, and tumor-suppressor genes has often been observed. Seventeen of the 88 listed CFSs have been analyzed at the molecular level, but the basis of their fragility has not been clarified. In the present work, the nine genes TGFB2, IARS2, MARK1, TAF1A, TP53BP2, ADPRT, including a very large gene ESRRG and two microRNA genes, MIRN194-1 and MIRN215, localized in the fragile site FRA1H, were investigated by polymerase chain reaction (PCR) for homozygous deletions and by real-time PCR for modification or loss of gene expression in a panel of 19 cancer cell lines. The expression level of five (ESRRG, TGFB2, MIRN194-1, MIRN215, and MARK1) of the nine genes studied presented significant modifications in some of the 19 examined tumor-derived cell lines compared to their normal control tissues. Because of their function, these genes could have a role in neoplastic transformation. PMID:17954271

  4. Bloodborne Pathogens Exposure Control Plan.

    ERIC Educational Resources Information Center

    National Child Care Association, Atlanta, GA.

    This sample exposure control plan is a guide to assist child care providers in complying with the blood-borne pathogens standard issued by the Occupational Safety and Health Administration (OSHA). The standard requires employers to establish a written exposure control plan by May 5, 1992 (for exposure to microorganisms in human blood that cause…

  5. Five Essentials of Emergency Planning

    ERIC Educational Resources Information Center

    Barnes, Jill M.

    2011-01-01

    Principals and other administrators seem to be perpetually overworked. There is always something that still needs to be done at the end of the day, and it is easy for disaster planning and preparedness to keep slipping to the bottom of the list. However, disaster preparation is essential, even when planning for the unknown. At some point in every…

  6. 45 CFR 400.7 - Submittal of the State plan and plan amendments for Governor's review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State Plan §...

  7. 45 CFR 400.7 - Submittal of the State plan and plan amendments for Governor's review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State Plan §...

  8. 45 CFR 400.7 - Submittal of the State plan and plan amendments for Governor's review.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Grants to States for Refugee Resettlement The State Plan §...

  9. 77 FR 44306 - Service Delivery Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... ADMINISTRATION Service Delivery Plan AGENCY: Social Security Administration (SSA). ACTION: Notice; request for comments. SUMMARY: We are requesting public input as we develop our Service Delivery Plan (SDP). We...) Deliver quality disability decisions and services; (2) provide quality service to the public; (3)...

  10. 78 FR 15797 - Service Delivery Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... provide the best possible service. (77 FR 44306 (2012)). We have incorporated those suggestions into this... ADMINISTRATION Service Delivery Plan AGENCY: Social Security Administration (SSA). ACTION: Notice; request for comments. SUMMARY: We are requesting public input as we finalize our Service Delivery Plan (SDP)....

  11. Administration for Community Living

    MedlinePlus

    ... by Acting Assistant Secretary for Aging and ACL Administrator Edwin Walker at the HCBS Conference (08/29/ ... Remarks by Assistant Secretary on Aging and ACL Administrator Kathy Greenlee at the n4a Answers on Aging ...

  12. The New Administrative Computing.

    ERIC Educational Resources Information Center

    Green, Kenneth C.

    1988-01-01

    The past decade has seen dramatic changes in administrative computing, including more systems, more applications, a new group of computer users, and new opportunities for computer use in campus administration. (Author/MSE)

  13. Transportation Security Administration

    MedlinePlus

    ... content Official website of the Department of Homeland Security Transportation Security Administration When I fly can I bring my... ... to know if you could bring through the security checkpoint. Main menu Administrator Travel Security Screening Special ...

  14. NASA, NOAA administrators nominated

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    President Ronald Reagan recently said he intended to nominate James Montgomery Beggs as NASA Administrator and John V. Byrne as NOAA Administrator. These two positions are key scientific posts that have been vacant since the start of the Reagan administration on January 20. The President also said he intends to nominate Hans Mark as NASA Deputy Administrator. At press time, Reagan had not designated his nominee for the director of the Office of Science and Technology Policy.

  15. 14 CFR 152.105 - Sponsors and planning agencies: Airport planning.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Sponsors and planning agencies: Airport planning. 152.105 Section 152.105 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project...

  16. A Philosophy of Administration.

    ERIC Educational Resources Information Center

    Bruening, William H.

    Justification is given for paying relatively large salaries to college administrators, specifically the president or chancellor and the chief academic officer. Three administrative task areas are discussed as criteria: management, administration per se, and leadership. It is contended that only leadership can be used as a criterion for…

  17. School Business Administration.

    ERIC Educational Resources Information Center

    Jordan, K. Forbis; And Others

    This textbook reviews the principal concerns within each of 13 major responsibility areas in school business administration. The first chapter assesses the political, social, and economic context in which schools function and school administrators work. The role and function of the school business administrator within this context is addressed in…

  18. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of funds... $4,000 plus 10% of the amount of funds payable (and not transferred for use under another block...

  19. 7 CFR 1780.76 - Contract administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Contract administration. 1780.76 Section 1780.76 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Planning, Designing, Bidding, Contracting, Constructing and Inspections §...

  20. Cool Heads: Crisis Management for Administrators.

    ERIC Educational Resources Information Center

    Smiar, Nicholas P.

    1992-01-01

    Applies risk management models to child care administration. These models have been used by corporations to plan for crisis management. The formation of a crisis management policy and procedure is described, and features of effective communication during crises are outlined. (GLR)

  1. Answers for Administrators: PLDS Can Help.

    ERIC Educational Resources Information Center

    Robinson, Charles W.

    1989-01-01

    Discusses the value of statistics in public library administration and recent efforts by the federal government and the Public Library Association (PLA) to gather public library statistics. PLA's Public Library Data Service (PLDS) Statistical Report '88 and planned online availability are described. An inset shows data on salaries for beginning…

  2. Forecasting and Resource Allocation in Educational Administration

    ERIC Educational Resources Information Center

    Schaefer, Marguerite J.

    1977-01-01

    An awareness of all the forces affecting higher education today is not enough; carefully planned strategies to deal with them are also necessary for effective administration. Organizational-environmental concerns, the seven-component model for managing organizational complexity, and forecasting technologies are among topics discussed. (Editor/TA)

  3. Operations Research and Higher Education Administration.

    ERIC Educational Resources Information Center

    Cheng, T. C . E.

    1993-01-01

    Illustrates the uses of operations research (OR) in higher education administration by reviewing the higher education system's most significant operational problems: resource allocation, financial planning, budgeting, formation of student project groups, scheduling and classroom allocation, student registration, tuition and fee structure…

  4. Information System for Educational Policy and Administration.

    ERIC Educational Resources Information Center

    Clayton, J. C., Jr.

    Educational Information System (EIS) is a proposed computer-based data processing system to help schools solve current educational problems more efficiently. The system would allow for more effective administrative operations in student scheduling, financial accounting, and long range planning. It would also assist school trustees and others in…

  5. Administration of Athletics in Colleges and Universities.

    ERIC Educational Resources Information Center

    Steitz, Edward S., Ed.

    The purpose of this book was to make available the best thoughts and methods in the area of athletic administration in colleges and universities. The sections are: (1) The Role of Athletics in Education; (2) Business Procedures; (3) Equipment and Supplies; (4) Planning, Construction, and Maintenance of Facilities; (5) School Law and Legal…

  6. 24 CFR 576.108 - Administrative activities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Administrative activities. 576.108 Section 576.108 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY...

  7. The Education of Librarians for Data Administration.

    ERIC Educational Resources Information Center

    Koenig, Michael E. D.; Kochoff, Stephen T.

    1983-01-01

    Argues that the increasing importance of database management systems (DBMS) and recognition of the information dependency of business planning are creating new job opportunities for librarians/information technicians. Highlights include development and functions of DBMSs, data and database administration, potential for librarians, and implications…

  8. Quality Assurance: Administrator's Panacea or Pandemonium.

    ERIC Educational Resources Information Center

    Comerford, Ralph; Silverman, Wade H.

    Where mental health administrators used to rely on subjective judgments of senior clinicians to evaluate the effectiveness of mental health services, they now rely more on a quality assurance (QA) plan. The primary motive for undertaking a QA program should be better service. QA may start out being very expensive in terms of personnel and…

  9. Japanese Management Theory and Library Administration.

    ERIC Educational Resources Information Center

    Clayton, Peter

    1992-01-01

    Provides an overview of Japanese management theory and suggests applications to library administration. Highlights include participative management; shared decision making; long-term objectives; organizational philosophy; staff training and human resource development; strategic planning; staffing issues; cooperation; quality control; and total…

  10. Early Childhood Education: A Workbook for Administrators.

    ERIC Educational Resources Information Center

    Hewes, Dorothy; Hartman, Barbara

    Business management theory and principles as applied to the administration of early childhood programs are presented in this workbook. Following a brief survey of the historical background of early childhood education and current early childhood programs, information and guidance to help plan, operate, and evaluate program facilities are provided.…

  11. 9 CFR 145.2 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Administration. 145.2 Section 145.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING POULTRY General Provisions §...

  12. 9 CFR 145.2 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Administration. 145.2 Section 145.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING POULTRY General Provisions §...

  13. 9 CFR 145.2 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Administration. 145.2 Section 145.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING POULTRY General Provisions §...

  14. Program Evaluation Skills for Busy Administrators.

    ERIC Educational Resources Information Center

    Owens, Thomas R.; Evans, Warren D.

    This manual was designed for the administrator who has the responsibility for conducting all or part of an evaluation or is responsible for using evaluation results in program planning. The manual provides step-by-step guidelines to help: identify the purposes and audiences of an evaluation; prepare a basic description of the program or activity;…

  15. School Administrator's Guide to Implementing Language Programming

    ERIC Educational Resources Information Center

    Alberta Education, 2007

    2007-01-01

    The "School Administrator's Guide to Implementing Language Programming" serves as a starting point to plan for and implement language programming. It provides a general overview; suggests practical strategies for working with students, parents, teachers and the surrounding community; and includes details on areas to address in selecting and…

  16. Hospital Organization, Administration and Wellness Programming.

    ERIC Educational Resources Information Center

    Fleming, Jeanne Hmura

    1984-01-01

    Hospital organization, administration and planning, and implementation program procedures are reviewed in this article. Hospitals and medical centers are changing their strategies in the area of wellness programming since they offer the appropriate facilities for these programs. Various types of wellness programs currently being promoted are…

  17. Bibliography. College and University Business Administration.

    ERIC Educational Resources Information Center

    National Association of College and University Business Officers, Washington, DC.

    This regularly-updated bibliography is organized by chapter and is generally limited to publications that have specific application to colleges and universities. The chapters include: business administration in higher education; institutional planning; management information systems and data processing; risk management and insurance;…

  18. 7 CFR 1491.2 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CFR part 12; and (10) Provide leadership for establishing, implementing, and overseeing administrative... entity; (5) Ensure a conservation plan is developed in accordance with 7 CFR part 12; (6) Make funding... supervision and direction of the NRCS Chief. (b) NRCS shall— (1) Provide overall program management...

  19. 7 CFR 1491.2 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CFR part 12; and (10) Provide leadership for establishing, implementing, and overseeing administrative... entity; (5) Ensure a conservation plan is developed in accordance with 7 CFR part 12; (6) Make funding... supervision and direction of the NRCS Chief. (b) NRCS shall— (1) Provide overall program management...

  20. 23 CFR 450.208 - Coordination of planning process activities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Coordination of planning process activities. 450.208 Section 450.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.208 Coordination of planning process activities. (a)...