Science.gov

Sample records for administration hhs action

  1. 42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... findings of research misconduct and HHS administrative actions. (a) When the ORI makes a finding of research misconduct or seeks to impose or enforce HHS administrative actions, other than debarment or... 42 Public Health 1 2010-10-01 2010-10-01 false Notifying the respondent of findings of...

  2. 42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... findings of research misconduct and HHS administrative actions. (a) When the ORI makes a finding of research misconduct or seeks to impose or enforce HHS administrative actions, other than debarment or... 42 Public Health 1 2011-10-01 2011-10-01 false Notifying the respondent of findings of...

  3. 42 CFR 93.411 - Final HHS action with settlement or finding of research misconduct.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Health and Human Services Research Misconduct Issues § 93.411 Final HHS action with settlement or finding of research misconduct. When a final HHS action results in a settlement or research misconduct... 42 Public Health 1 2011-10-01 2011-10-01 false Final HHS action with settlement or finding...

  4. 42 CFR 93.411 - Final HHS action with settlement or finding of research misconduct.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Health and Human Services Research Misconduct Issues § 93.411 Final HHS action with settlement or finding of research misconduct. When a final HHS action results in a settlement or research misconduct... 42 Public Health 1 2010-10-01 2010-10-01 false Final HHS action with settlement or finding...

  5. 42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or finding of research misconduct. When the final HHS action does not result in a settlement or finding of... 42 Public Health 1 2011-10-01 2011-10-01 false Final HHS action with no settlement or finding...

  6. 42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or finding of research misconduct. When the final HHS action does not result in a settlement or finding of... 42 Public Health 1 2010-10-01 2010-10-01 false Final HHS action with no settlement or finding...

  7. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to contest findings of research misconduct and administrative actions. (a) Opportunity to contest. A respondent may contest ORI findings of research misconduct and HHS administrative actions, including...

  8. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to contest findings of research misconduct and administrative actions. (a) Opportunity to contest. A respondent may contest ORI findings of research misconduct and HHS administrative actions, including...

  9. Data-driven. HHS unleashes wave of public health data so software developers can create tools to raise awareness, spur action.

    PubMed

    Conn, Joseph

    2010-06-01

    Guided by how weather data from the National Oceanic and Atmospheric Administration fuels all kinds of weather reports, maps and forecasts, HHS officials saw parallels on how to distribute health data so software developers could create tools to be used by patients and providers. "We thought that was inspiring," said Todd Park, left, HHS' chief technology officer.

  10. Medical devices; revocation of cardiac pacemaker registry. Food and Drug Administration, HHS. Final rule.

    PubMed

    1999-11-24

    The Food and Drug Administration (FDA) is issuing a final rule to revoke a regulation requiring a cardiac pacemaker registry. The registry, which was mandated by the Deficit Reduction Act of 1984, requires any physician and any provider of services who requests or receives Medicare payment for an implantation, removal, or replacement of permanent cardiac pacemaker devices and pacemaker leads to submit certain information to the registry. The information is used by FDA to track the performance of permanent cardiac pacemakers and pacemaker leads and by the Health Care Finance Administration (HCFA) to administer its Medicare payment program for these devices. This action is being taken to implement an act to Repeal An Unnecessary Medical Device Reporting Requirement passed by Congress in 1996 to remove the cardiac pacemaker registry to eliminate duplicative and unnecessary reporting. PMID:11010690

  11. Administrative Actions for Noncompliance; Lesser Administrative Actions. Direct final rule.

    PubMed

    2016-04-01

    The Food and Drug Administration (FDA) is amending the regulation describing lesser administrative actions that may be imposed on an Institutional Review Board (IRB) that has failed to comply with FDA's IRB regulations. We are clarifying that FDA may require the IRB to withhold approval of new FDA-regulated studies, stop the enrollment of new subjects in ongoing studies, and terminate ongoing studies, or any combination of these actions until the noncompliance with FDA's IRB regulations is corrected. We are taking this action to ensure clarity and improve the accuracy of the regulations.

  12. Temporary Assistance for Needy Families program (TANF). Administration for Children and Families, HHS. Final rule.

    PubMed

    1999-04-12

    The Administration for Children and Families (ACF) issues regulations governing key provisions of the new welfare block grant program enacted in 1996--the Temporary Assistance for Needy Families, or TANF, program. It replaces the national welfare program know as Aid to Families with Dependent Children (AFDC) and the related programs known as the Job Opportunities and Basic Skills Training Program (JOBS) and the Emergency Assistance (EA) program. These rules reflect new Federal, State, and Tribal relationships in the administration of welfare programs; a new focus on moving recipients into work; and a new emphasis on program information, measurement, and performance. They also reflect the Administration's commitment to regulatory reform.

  13. Unified agenda of federal regulatory and deregulatory actions--HHS. Semiannual regulatory agenda.

    PubMed

    1998-11-01

    The President's Executive Order 12866 and the Regulatory Flexibility Act of 1980 require the semiannual publication of an agenda which summarizes all current, projected, and recently completed rulemakings of the Department. The agenda informs the public about regulatory actions that are under development within the components of the Department, and it provides all concerned with the opportunity to participate in this work at an early stage. The last such agenda was published on April 27, 1998.

  14. Listing of color additives for coloring sutures; [phthalocyaninato(2-)] copper. Food and Drug Administration, HHS. Final rule.

    PubMed

    1999-04-30

    The Food and Drug Administration (FDA) is amending the color additive regulations to provide for the safe use of [phthalocyaninato(2-)] copper in coloring nonabsorbable sutures for general and ophthalmic surgery made from a blend of poly(vinylidene fluoride) and poly(vinylidene fluoride-co-hexafluoropropylene). This action responds to a petition filed by Ethicon, Inc.

  15. Listing of color additives for coloring sutures; [phthalocyaninato(2-)] copper. Food and Drug Administration, HHS. Final rule.

    PubMed

    1999-04-30

    The Food and Drug Administration (FDA) is amending the color additive regulations to provide for the safe use of [phthalocyaninato(2-)] copper in coloring nonabsorbable sutures for general and ophthalmic surgery made from a blend of poly(vinylidene fluoride) and poly(vinylidene fluoride-co-hexafluoropropylene). This action responds to a petition filed by Ethicon, Inc. PMID:10558496

  16. Medical devices; exemption from premarket notification and reserved devices; class I. Food and Drug Administration, HHS. Final rule.

    PubMed

    2000-01-14

    The Food and Drug Administration (FDA) is amending its classification regulations to designate class I devices that are exempt from the premarket notification requirements, subject to certain limitations, and to designate those class I devices that remain subject to premarket notification requirements under the new statutory criteria for premarket notification requirements. The devices FDA is designating as exempt do not include class I devices that have been previously exempted by regulation from the premarket notification requirements. This action is being taken under the Federal Food, Drug, and Cosmetic Act (the act), as amended by the Medical Device Amendments of 1976 (the 1976 amendments), the Safe Medical Devices Act of 1990 (SMDA), and the FDA Modernization Act of 1997 (FDAMA). FDA is taking this action in order to implement a requirement of FDAMA. Elsewhere in this issue of the Federal Register, FDA is announcing that it is withdrawing proposed rules to revoke existing exemptions from premarket notification for two devices. PMID:11010655

  17. 14 CFR 1275.106 - Administrative actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Administrative actions. 1275.106 Section 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.106 Administrative actions. (a) Listed in paragraphs (a)(1) through (a)(3) of this section...

  18. 14 CFR 1275.106 - Administrative actions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Administrative actions. 1275.106 Section 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.106 Administrative actions. (a) Listed in paragraphs (a)(1) through (a)(3) of this section...

  19. 14 CFR 1275.106 - Administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Administrative actions. 1275.106 Section 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.106 Administrative actions. (a) Listed in paragraphs (a)(1) through (a)(3) of this section...

  20. 14 CFR 1275.106 - Administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Administrative actions. 1275.106 Section 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.106 Administrative actions. (a) Listed in paragraphs (a)(1) through (a)(3) of this section...

  1. 42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... or nonexistence of any factor is not determinative: (a) Knowing, intentional, or reckless. Were the... misconduct an isolated event or part of a continuing or prior pattern of dishonest conduct? (c) Impact. Did the misconduct have significant impact on the proposed or reported research record, research...

  2. Bonus to reward states for high performance under the TANF program. Administration for Children and Families, HHS. Final rule.

    PubMed

    2000-08-30

    The Administration for Children and Families is issuing final regulations to implement section 403(a)(4) of the Social Security Act. This provision authorizes bonuses to high performing States in meeting the purposes of the Temporary Assistance for Needy Families Block Grant (the TANF program). We will base the bonus awards in FY 2002 and beyond on work measures (substantially the same work measures currently in effect for the FY 1999-2001 awards); measures that support work and self-sufficiency related to: participation by low-income working families in the Food Stamp Program, participation of former TANF recipients in the Medicaid and State Children's Health Insurance Programs (SCHIP), and receipt of child care subsidies; and a measure related to family formation and stability (increase in the number of children in the State who reside in married couple families). Bonus funds of up to $200 million each year were authorized for awards in fiscal years 1999 through 2003. This rule specifies a formula for allocating these funds in FY 2002 and FY 2003. The amount awarded to each high performing State may not exceed five percent of the State's family assistance grant. Earlier, we issued program guidance covering bonus awards in FY 1999, FY 2000, and FY 2001. We published a Notice of Proposed Rulemaking to cover awards beginning in FY 2002 on December 6, 1999 (64 FR 68202). In a related regulatory action, we are amending 45 CFR Part 265, the TANF Data Collection and Reporting Requirements, to reduce the burden of reporting data on Separate State Program-Maintenance of Effort (SSP-MOE) programs. This amendment will allow waivers of certain reporting requirements under limited circumstances.

  3. 29 CFR 15.6 - Administrative action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Secretary of Labor ADMINISTRATIVE CLAIMS UNDER THE FEDERAL TORT CLAIMS ACT AND RELATED STATUTES Claims Against the Government Under the Federal Tort Claims Act § 15.6 Administrative action. (a... of an administrative claim under the Act or of notice of litigation seeking damages for an...

  4. 42 CFR 93.523 - The Administrative Law Judge's ruling.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an...

  5. Medical device reporting: manufacturer reporting, importer reporting, user facility reporting, distributor reporting. Food and Drug Administration, HHS. Final rule.

    PubMed

    2000-01-26

    The Food and Drug Administration (FDA) is amending its regulations governing reporting by manufacturers, importers, distributors and health care (user) facilities of adverse events related to medical devices. Amendments are being made to implement revisions to the Federal Food, Drug, and Cosmetic Act (the act) as amended by the Food and Drug Administration Modernization Act of 1997 (FDAMA).

  6. 78 FR 15957 - Food and Drug Administration/Xavier University Global Medical Device Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA) Cincinnati District, in cosponsorship with...

  7. 77 FR 10537 - Food and Drug Administration/Xavier University Global Medical Device Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA) Cincinnati District, in cosponsorship with...

  8. 77 FR 14403 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document: Norovirus Serological Reagents; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA)...

  9. 42 CFR 93.200 - Administrative action.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Administrative action. 93.200 Section 93.200 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  10. 42 CFR 93.200 - Administrative action.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Administrative action. 93.200 Section 93.200 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  11. 42 CFR 93.200 - Administrative action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Administrative action. 93.200 Section 93.200 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  12. 42 CFR 93.200 - Administrative action.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Administrative action. 93.200 Section 93.200 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  13. 42 CFR 93.200 - Administrative action.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Administrative action. 93.200 Section 93.200 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  14. 76 FR 50484 - Draft Guidance for Industry, Clinical Investigators, and Food and Drug Administration Staff...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry, Clinical Investigators, and Food and Drug Administration Staff; Design Considerations for Pivotal Clinical Investigations for Medical Devices; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The...

  15. 76 FR 61366 - Food and Drug Administration Transparency Initiative: Draft Proposals for Public Comment to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Transparency Initiative: Draft Proposals for Public Comment to Increase Transparency By Promoting Greater Access to the Agency's Compliance and Enforcement Data; Availability AGENCY: Food and Drug Administration, HHS. ] ACTION: Notice...

  16. 76 FR 9027 - Draft Guidance for Industry and Food and Drug Administration Staff on Best Practices for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration... Electronic Healthcare Data Sets; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... industry and FDA staff entitled ``Best Practices for Conducting and Reporting Pharmacoepidemiologic...

  17. 77 FR 14404 - Guidance for the Public, Food and Drug Administration (FDA) Advisory Committee Members, and FDA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... HUMAN SERVICES Food and Drug Administration Guidance for the Public, Food and Drug Administration (FDA) Advisory Committee Members, and FDA Staff: Public Availability of Advisory Committee Members' Financial Interest Information and Waivers; Availability AGENCY: Food and Drug Administration, HHS. ACTION:...

  18. 5 CFR 930.211 - Actions against administrative law judges.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Actions against administrative law judges. 930.211 Section 930.211 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.211 Actions against administrative law judges. (a) Procedures. An...

  19. 5 CFR 930.211 - Actions against administrative law judges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Actions against administrative law judges. 930.211 Section 930.211 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.211 Actions against administrative law judges. (a) Procedures. An...

  20. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  1. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  2. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  3. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  4. 42 CFR 93.506 - Authority of the Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.506 Authority of the Administrative Law Judge. (a) The ALJ...

  5. 77 FR 11149 - Mortgagee Review Board: Administrative Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... advises of the cause and description of administrative actions taken by HUD's Mortgagee Review Board... in the Federal Register a description of and the cause for administrative action against a mortgagee... FHA approval of Action Mortgage Corporation (``AMC''). Cause: The Board took this action based on...

  6. 42 CFR 93.515 - Actions for violating an order or for disruptive conduct.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.515 Actions for violating an order or...

  7. 14 CFR § 1275.106 - Administrative actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Administrative actions. § 1275.106 Section § 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.106 Administrative actions. (a) Listed in paragraphs (a)(1) through (a)(3) of this section...

  8. 14 CFR 1245.115 - Action by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Action by the Administrator. 1245.115... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.115 Action by the Administrator. (a) After receiving the transmittal from the Board, the Administrator shall determine, in accordance with the...

  9. 5 CFR 179.218 - Additional administrative collection action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Additional administrative collection action. 179.218 Section 179.218 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Salary Offset § 179.218 Additional administrative collection...

  10. 40 CFR 72.96 - Administrator's action on compliance certifications.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false Administrator's action on compliance certifications. 72.96 Section 72.96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PERMITS REGULATION Compliance Certification § 72.96 Administrator's action on compliance certifications. (a)...

  11. 40 CFR 72.96 - Administrator's action on compliance certifications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Administrator's action on compliance certifications. 72.96 Section 72.96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PERMITS REGULATION Compliance Certification § 72.96 Administrator's action on compliance certifications. (a)...

  12. 40 CFR 72.96 - Administrator's action on compliance certifications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false Administrator's action on compliance certifications. 72.96 Section 72.96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PERMITS REGULATION Compliance Certification § 72.96 Administrator's action on compliance certifications. (a)...

  13. 40 CFR 72.96 - Administrator's action on compliance certifications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on compliance certifications. 72.96 Section 72.96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PERMITS REGULATION Compliance Certification § 72.96 Administrator's action on compliance certifications. (a)...

  14. 29 CFR 15.6 - Administrative action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Secretary of Labor ADMINISTRATIVE CLAIMS UNDER THE FEDERAL TORT CLAIMS ACT AND RELATED STATUTES (Eff. until 7-12-12) Claims Against the Government Under the Federal Tort Claims Act § 15.6...) Notification. Upon receipt of an administrative claim under the Act or of notice of litigation seeking...

  15. 76 FR 569 - Draft Guidance for Industry and Food and Drug Administration Staff; Establishing the Performance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... for the Detection and Differentiation of Methicillin-Resistant Staphylococcus aureus and Staphylococcus aureus; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. ] SUMMARY: The... Detection and Differentiation of Methicillin-Resistant Staphylococcus aureus (MRSA) and...

  16. 75 FR 22412 - Food and Drug Administration/Xavier University Global Outsourcing Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Outsourcing Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY..., is announcing a public conference entitled ``FDA/Xavier University Global Outsourcing Conference... challenges associated with pharmaceutical outsourcing relationships and supply chain control, as well...

  17. 77 FR 41416 - Food and Drug Administration/Xavier University Global Outsourcing Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... Outsourcing Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY..., is announcing a public conference entitled ``FDA/Xavier University Global Outsourcing Conference... experts. This conference drives collaboration on the topic of global outsourcing compliance by...

  18. 76 FR 56770 - Food and Drug Administration/Xavier University Global Outsourcing Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... Outsourcing Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY..., is announcing a public conference entitled ``FDA/Xavier University Global Outsourcing Conference... industry experts. This conference drives collaboration on the topic of global outsourcing compliance...

  19. 21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... Commissioner concludes that the public interest requires that the action remain in effect pending further... requires that the action remain in effect pending further court or administrative proceedings, the...

  20. 40 CFR 26.1502 - Lesser administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Lesser administrative actions. 26.1502 Section 26.1502 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... corrective action, the Agency may: (1) Withhold approval of new studies subject to the requirements of...

  1. 40 CFR 26.1502 - Lesser administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Lesser administrative actions. 26.1502 Section 26.1502 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... corrective action, the Agency may: (1) Withhold approval of new studies subject to the requirements of...

  2. 43 CFR 4.439 - Action by administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Action by administrative law judge. 4.439 Section 4.439 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES Special Rules Applicable to Public Land Hearings and Appeals Hearings on Appeals Involving Questions of Fact § 4.439 Action...

  3. 12 CFR 615.5361 - Relation to other administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Relation to other administrative actions. 615.5361 Section 615.5361 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Issuance of a Capital...

  4. 21 CFR 10.33 - Administrative reconsideration of action.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Administrative reconsideration of action. 10.33 Section 10.33 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL... publication is the day of decision. (Date) Division of Dockets Management, Food and Drug...

  5. 42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures...

  6. 42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures...

  7. The HHS Mandate and Religious Liberty: A Primer

    ERIC Educational Resources Information Center

    Keim, Adele Auxier

    2013-01-01

    "We are in a war," Health and Human Services Secretary Kathleen Sebelius declared to cheers at a 2011 National Abortion and Reproductive Rights Action League (NARAL) Pro-Choice America fund-raiser. Secretary Sebelius was referring in part to the uproar caused by the "HHS Mandate," her agency's rule that employer-provided…

  8. 40 CFR 97.31 - Administrator's action on compliance certifications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Administrator's action on compliance certifications. 97.31 Section 97.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS...

  9. 7 CFR 1403.12 - Additional administrative collection action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Additional administrative collection action. 1403.12 Section 1403.12 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES DEBT SETTLEMENT POLICIES...

  10. 44 CFR 350.11 - Action by FEMA Regional Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Action by FEMA Regional Administrator. 350.11 Section 350.11 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS REVIEW AND APPROVAL OF STATE AND LOCAL RADIOLOGICAL...

  11. 44 CFR 350.11 - Action by FEMA Regional Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Action by FEMA Regional Administrator. 350.11 Section 350.11 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS REVIEW AND APPROVAL OF STATE AND LOCAL RADIOLOGICAL...

  12. Institutional Image: The Concept and Implications for Administrative Action.

    ERIC Educational Resources Information Center

    Renihan, Frederick I; Renihan, Patrick J.

    1989-01-01

    Explores institutional image as a key to providing a philosophy and a logical foundation for school improvement efforts. Identifies two image dimensions (cosmetic and pastoral) and classifies five school types (synergistic, candy store, disaffected, monastic, and survivor), and discusses implications for administrative action. Includes three…

  13. 45 CFR 689.8 - Interim administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... taken to protect Federal resources or to guard against continuation of any suspected or alleged...

  14. 45 CFR 689.8 - Interim administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... taken to protect Federal resources or to guard against continuation of any suspected or alleged...

  15. Help Teachers Engage Students: Action Tools for Administrators

    ERIC Educational Resources Information Center

    Brinkman, Annette; Forlini, Gary; Williams, Ellen

    2009-01-01

    This unique, hands-on reference for school administrators offers guidelines for effective student engagement as well as reproducible action tools that will enable you to: (1) Identify and share "The Big Eight Student Engagement Strategies" with your teachers; (2) Promote teacher growth and provide support for new and/or struggling teachers; (3)…

  16. 5 CFR 890.908 - Notification of HHS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....908 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES HEALTH BENEFITS PROGRAM Limit on Inpatient Hospital Charges, Physician Charges..., will notify the Secretary of HHS, or the Secretary's designee, if the plan finds that: (a) A...

  17. 78 FR 59038 - Mobile Medical Applications; Guidance for Industry and Food and Drug Administration Staff...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... HUMAN SERVICES Food and Drug Administration Mobile Medical Applications; Guidance for Industry and Food and Drug Administration Staff; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of the guidance...

  18. 75 FR 74063 - Supplemental Funding Under the Food and Drug Administration's Convener of Active Medical Product...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... HUMAN SERVICES Food and Drug Administration Supplemental Funding Under the Food and Drug Administration... Supplemental Application AGENCY: Food and Drug Administration, HHS. ACTION: Notice of intent. SUMMARY: The Food and Drug Administration (FDA) is announcing a program expansion of its Conference...

  19. 76 FR 70150 - Draft Guidance for Industry and Food and Drug Administration Staff; Investigational Device...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration..., Including Certain First in Human Studies; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a...

  20. 75 FR 16345 - Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ..., 301-827-7010. SUPPLEMENTARY INFORMATION: FDA is amending its administrative regulations in 21 CFR part.... 10.90 Food and Drug Administration regulations, recommendations, and agreements. (a) Regulations. FDA... Administration, HHS. ACTION: Final rule; technical amendment. SUMMARY: The Food and Drug Administration (FDA)...

  1. 75 FR 15439 - Food and Drug Administration/Xavier University Global Medical Device Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration/Xavier University Global Medical Device Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. SUMMARY: The Food and Drug Administration (FDA) Cincinnati District, in co-sponsorship with...

  2. 75 FR 11893 - Food and Drug Administration Transparency Task Force; Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Transparency Task Force; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice; request for comments. SUMMARY: The Food and Drug Administration (FDA) is soliciting comments from interested persons on ways...

  3. 76 FR 30727 - Food and Drug Administration Food Safety Modernization Act: Focus on Inspections and Compliance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Food Safety Modernization Act: Focus on Inspections and Compliance AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public meeting; request for comments. SUMMARY: The Food and Drug Administration (FDA) is announcing a...

  4. 77 FR 39498 - Guidances for Industry and Food and Drug Administration Staff: Computer-Assisted Detection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... HUMAN SERVICES Food and Drug Administration Guidances for Industry and Food and Drug Administration... Approval and Premarket Notification (510(k)) Submissions; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability...

  5. 75 FR 13766 - Food and Drug Administration and Process Analytical Technology for Pharma Manufacturing: Food and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration and Process Analytical Technology for Pharma Manufacturing: Food and Drug Administration--Partnering With Industry; Public Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. The Food and...

  6. 78 FR 30317 - Science Board to the Food and Drug Administration; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... HUMAN SERVICES Food and Drug Administration Science Board to the Food and Drug Administration; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice announces a forthcoming meeting of a public advisory committee of the Food and Drug Administration (FDA). The meeting will be...

  7. 42 CFR 93.506 - Authority of the Administrative Law Judge.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.506 Authority of the Administrative Law Judge. (a) The ALJ assigned... communication; (17) Take action against any party for failing to follow an order or procedure or for...

  8. 78 FR 101 - Guidance for Industry and Food and Drug Administration Staff; Acceptance and Filing Reviews for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; Acceptance and Filing Reviews for Premarket Approval Applications; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing...

  9. 77 FR 63837 - Draft Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical Device Submissions; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability...

  10. 76 FR 48870 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff...; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug..., Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 66, rm. 4613, Silver Spring, MD...

  11. 78 FR 28228 - Guidance for Industry and Food and Drug Administration Staff on Best Practices for Conducting and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff... Healthcare Data; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry and FDA...

  12. 76 FR 77542 - Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian Use Device...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian Use Device Designations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a...

  13. 76 FR 20688 - Guidance for Industry and Food and Drug Administration Staff; 30-Day Notices, 135-Day Premarket...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... Supplements for Manufacturing Method or Process Changes; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration...

  14. 78 FR 102 - Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical Device...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; eCopy Program for Medical Device Submissions; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of...

  15. 78 FR 15019 - Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Prescription Drug User Fee Act V Benefit-Risk Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice, request for comments. SUMMARY: The Food and Drug Administration (FDA or the Agency) is announcing...

  16. 75 FR 18219 - Drug and Medical Device Forum on Food and Drug Administration Drug and Device Requirements and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... HUMAN SERVICES Food and Drug Administration Drug and Medical Device Forum on Food and Drug Administration Drug and Device Requirements and Supplier Controls; Public Educational Forum AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public educational forum. SUMMARY: The Food and Drug Administration...

  17. 77 FR 70166 - Provisions of the Food and Drug Administration Safety and Innovation Act Related to Medical Gases...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... HUMAN SERVICES Food and Drug Administration Provisions of the Food and Drug Administration Safety and Innovation Act Related to Medical Gases; Establishment of a Public Docket AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is establishing a...

  18. 42 CFR 93.523 - The Administrative Law Judge's ruling.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... accordance with 45 CFR 76.845(c). The decision of the debarring official on debarment or suspension is...

  19. 78 FR 6824 - Considerations Regarding Food and Drug Administration Review and Regulation of Drugs for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... HUMAN SERVICES Food and Drug Administration Considerations Regarding Food and Drug Administration Review and Regulation of Drugs for the Treatment of Amyotrophic Lateral Sclerosis; Public Hearing AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public hearing; request for comments. SUMMARY:...

  20. 76 FR 78931 - Food and Drug Administration Rare Disease Patient Advocacy Day; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Rare Disease Patient Advocacy Day; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. The Food and Drug... Disease Patient Advocacy Day. This meeting is intended to enhance the awareness of the rare...

  1. 76 FR 68767 - Draft Guidance for Industry and Food and Drug Administration Staff; De Novo Classification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration Staff; De Novo Classification Process (Evaluation of Automatic Class III Designation); Availability; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notice; extension of...

  2. 5 CFR 1201.142 - Actions filed by administrative law judges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... complaint with the Board under this subpart. The filing and serving requirements of 5 CFR 1201.37 apply... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Actions filed by administrative law... Administrative Law Judges § 1201.142 Actions filed by administrative law judges. An administrative law judge...

  3. 42 CFR 93.515 - Actions for violating an order or for disruptive conduct.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Actions for violating an order or for disruptive... PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.515 Actions for violating an order or...

  4. 78 FR 73195 - Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... HUMAN SERVICES Centers for Medicare & Medicaid Services Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching Program Match No. 1312 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer...

  5. 78 FR 49525 - Privacy Act of 1974; CMS Computer Match No. 2013-06; HHS Computer Match No. 1308

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... HUMAN SERVICES Centers for Medicare & Medicaid Services Privacy Act of 1974; CMS Computer Match No. 2013-06; HHS Computer Match No. 1308 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer Matching Program (CMP). SUMMARY:...

  6. 78 FR 42086 - Draft Guidance for Industry on Arsenic in Apple Juice: Action Level; Supporting Document for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-15

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Arsenic in Apple Juice: Action Level; Supporting Document for Action Level for Arsenic in Apple Juice; A Quantitative Assessment of Inorganic Arsenic in Apple Juice; Availability AGENCY: Food and Drug Administration, HHS....

  7. 77 FR 37058 - Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration...; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... Manufacturers, International and Consumer Assistance, Center for Devices and Radiological Health, Food and...

  8. 78 FR 36711 - Food and Drug Administration Safety and Innovation Act Title VII-Drug Supply Chain; Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Chapter I Food and Drug Administration Safety and Innovation Act Title VII--Drug Supply Chain; Standards for Admission of Imported Drugs, Registration of...: Food and Drug Administration, HHS. ACTION: Notification of public meeting; request for...

  9. 25 CFR 41.6 - HHS participation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GRANTS TO TRIBALLY CONTROLLED COMMUNITY COLLEGES AND NAVAJO COMMUNITY COLLEGE Tribally Controlled Community Colleges § 41.6 HHS participation. The Assistant... College....

  10. 25 CFR 41.6 - HHS participation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GRANTS TO TRIBALLY CONTROLLED COMMUNITY COLLEGES AND NAVAJO COMMUNITY COLLEGE Tribally Controlled Community Colleges § 41.6 HHS participation. The Assistant... College....

  11. 75 FR 17418 - Memorandum of Understanding Between the Food and Drug Administration, United States Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... Health AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Memorandum of Understanding Between the Food and...

  12. 42 CFR 93.502 - Appointment of the Administrative Law Judge and scientific expert.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.502 Appointment of the Administrative Law... expertise to assist the ALJ in evaluating scientific or technical issues related to the findings of...

  13. 77 FR 41415 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Single-Ingredient, Immediate-Release Drug Products... AGENCY: Food and Drug Administration, HHS. ACTION: Notice; correction. SUMMARY: The Food and...

  14. 42 CFR 93.502 - Appointment of the Administrative Law Judge and scientific expert.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.502 Appointment of the Administrative Law... expertise to assist the ALJ in evaluating scientific or technical issues related to the findings of...

  15. 23 CFR 810.208 - Action by the Federal Highway Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC... Transit Projects § 810.208 Action by the Federal Highway Administrator. The Federal Highway...

  16. 23 CFR 810.208 - Action by the Federal Highway Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC... Transit Projects § 810.208 Action by the Federal Highway Administrator. The Federal Highway...

  17. 23 CFR 810.208 - Action by the Federal Highway Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC... Transit Projects § 810.208 Action by the Federal Highway Administrator. The Federal Highway...

  18. 21 CFR 1316.94 - Posting of substitute res in an administrative forfeiture action.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Posting of substitute res in an administrative forfeiture action. 1316.94 Section 1316.94 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF... Property § 1316.94 Posting of substitute res in an administrative forfeiture action. (a) Where property...

  19. 40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water Act. Unless the Administrator...

  20. 40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water Act. Unless the Administrator...

  1. 40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water Act. Unless the Administrator...

  2. 75 FR 32953 - Guidance for Industry and Food and Drug Administration Staff; Use of “Light,” “Mild,” “Low,” or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; Use of ``Light,'' ``Mild,'' ``Low,'' or Similar Descriptors in the Label, Labeling, or Advertising of Tobacco Products; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY:...

  3. 75 FR 22599 - Draft Guidance for Industry and Food and Drug Administration Staff; Food and Drug Administration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... Under the Federal Food, Drug, and Cosmetic Act AGENCY: Food and Drug Administration, HHS. ACTION: Notice...) Requests for Information Under the Federal Food, Drug, and Cosmetic Act.'' This draft guidance is not final...) Requests for Information Under the Federal Food, Drug, and Cosmetic Act'' to the Division of...

  4. 40 CFR 300.815 - Administrative record file for a remedial action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  5. 40 CFR 300.820 - Administrative record file for a removal action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  6. 40 CFR 300.815 - Administrative record file for a remedial action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  7. 40 CFR 300.820 - Administrative record file for a removal action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  8. 40 CFR 300.820 - Administrative record file for a removal action.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  9. 40 CFR 300.820 - Administrative record file for a removal action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  10. 40 CFR 300.815 - Administrative record file for a remedial action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  11. 40 CFR 300.820 - Administrative record file for a removal action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  12. 40 CFR 300.815 - Administrative record file for a remedial action.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  13. 40 CFR 300.815 - Administrative record file for a remedial action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action §...

  14. 5 CFR 5501.102 - Designation of HHS components as separate agencies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Pursuant to 5 CFR 2635.203(a), each of the twelve components of HHS listed below is designated as an agency... agencies for purposes of applying any provision of 5 CFR part 2635 or this part to employees of the... Administration; (8) Health Resources and Services Administration; (9) Indian Health Service; (10)...

  15. 76 FR 74791 - Memorandum of Understanding Between the Food and Drug Administration and the U.S. Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... HUMAN SERVICES Food and Drug Administration Memorandum of Understanding Between the Food and Drug..., and Food Nutrition Service AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The... Food Nutrition Service. The purpose of the MOU is to provide a framework for the parties to...

  16. 78 FR 9928 - Food and Drug Administration Drug Shortages Task Force and Strategic Plan; Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Strategic Plan; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION: Notice; request for comments. SUMMARY: To assist the Food and Drug Administration (FDA or Agency) in drafting a strategic plan... require the formation of a task force to develop and implement a strategic plan for enhancing the...

  17. HHS circulating regulations finalized on June 17.

    PubMed

    Blackford, H M; Davis, N A; Dodd, P M; Gagne, R G; Teutsch, W J; Wherry, B I; Wilkins, S L; Zeitlin, K A

    1986-01-01

    On June 17, 1986, the US Department of Health and Human Services (HHS) published its final regulations in the Federal Register governing the hospital Conditions of Participation in Medicare and Medicaid programs. The final regulations state that "In accordance with applicable State laws and approved medical staff policies and procedures, ...surgical technologists may assist in circulatory duties under the supervision of a qualified registered nurse who is immediately available to respond to emergencies". Coming after a dozen years of exhaustive research and debate on the conditions, HHS deleted the work "direct" as it applies to the degree of supervision required for circulating surgical technologists because, HHS states, "it will give hospitals maximum flexibility to manage their internal procedures...and will recognize appropriately the special qualifications of surgical technologists". The following article will provide you with the historical background and development of this regulation, scheduled to take effect on September 15.

  18. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding...) The developer shall report to the Corporation periodically its progress in meeting the goals and..., and committed opportunities. In meeting the reporting requirements the developer shall: (1) Count...

  19. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding...) The developer shall report to the Corporation periodically its progress in meeting the goals and..., and committed opportunities. In meeting the reporting requirements the developer shall: (1) Count...

  20. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding...) The developer shall report to the Corporation periodically its progress in meeting the goals and..., and committed opportunities. In meeting the reporting requirements the developer shall: (1) Count...

  1. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding...) The developer shall report to the Corporation periodically its progress in meeting the goals and..., and committed opportunities. In meeting the reporting requirements the developer shall: (1) Count...

  2. 36 CFR 906.5 - Administration of affirmative action plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding...) The developer shall report to the Corporation periodically its progress in meeting the goals and..., and committed opportunities. In meeting the reporting requirements the developer shall: (1) Count...

  3. 75 FR 34750 - Web-Based Public Meeting To Discuss Issues Related to the Development of an Enforcement Action...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ... Access and Advertising Regulation). FDA published the final rule on March 19, 2010 (75 FR 13225) and the... HUMAN SERVICES Food and Drug Administration Web-Based Public Meeting To Discuss Issues Related to the... Administration, HHS. ACTION: Notice of Web-based public meeting; request for data, information, and...

  4. 40 CFR 78.6 - Action on petition for administrative review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Action on petition for administrative review. 78.6 Section 78.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPEAL PROCEDURES § 78.6 Action on petition for administrative review. (a) If...

  5. 40 CFR 77.4 - Administrator's action on proposed offset plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on proposed offset plans. 77.4 Section 77.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) EXCESS EMISSIONS § 77.4 Administrator's action on proposed offset plans....

  6. 40 CFR 23.3 - Timing of Administrator's action under Clean Air Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Clean Air Act. 23.3 Section 23.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.3 Timing of Administrator's action under Clean Air...

  7. 40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean...

  8. 40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean...

  9. 40 CFR 23.3 - Timing of Administrator's action under Clean Air Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Clean Air Act. 23.3 Section 23.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.3 Timing of Administrator's action under Clean Air...

  10. 40 CFR 23.3 - Timing of Administrator's action under Clean Air Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Clean Air Act. 23.3 Section 23.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.3 Timing of Administrator's action under Clean Air...

  11. 40 CFR 23.3 - Timing of Administrator's action under Clean Air Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Clean Air Act. 23.3 Section 23.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.3 Timing of Administrator's action under Clean Air...

  12. 40 CFR 23.6 - Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. 23.6 Section 23.6 Protection of Environment... Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. Unless the...

  13. 40 CFR 23.6 - Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. 23.6 Section 23.6 Protection of Environment... Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. Unless the...

  14. 40 CFR 23.6 - Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. 23.6 Section 23.6 Protection of Environment... Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. Unless the...

  15. 40 CFR 23.6 - Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. 23.6 Section 23.6 Protection of Environment... Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. Unless the...

  16. 40 CFR 23.6 - Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. 23.6 Section 23.6 Protection of Environment... Administrator's action under Federal Insecticide, Fungicide and Rodenticide Act. Unless the...

  17. 32 CFR 634.12 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Army administrative actions against intoxicated drivers. 634.12 Section 634.12 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... § 634.12 Army administrative actions against intoxicated drivers. Army commanders will take...

  18. 32 CFR 634.12 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Army administrative actions against intoxicated drivers. 634.12 Section 634.12 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... § 634.12 Army administrative actions against intoxicated drivers. Army commanders will take...

  19. 32 CFR 636.5 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... INSTALLATIONS) Fort Stewart, Georgia § 636.5 Army administrative actions against intoxicated drivers. For...

  20. 32 CFR 636.5 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... INSTALLATIONS) Fort Stewart, Georgia § 636.5 Army administrative actions against intoxicated drivers. For...

  1. 40 CFR 23.3 - Timing of Administrator's action under Clean Air Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Clean Air Act. 23.3 Section 23.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.3 Timing of Administrator's action under Clean Air...

  2. 32 CFR 636.5 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... INSTALLATIONS) Fort Stewart, Georgia § 636.5 Army administrative actions against intoxicated drivers. For...

  3. 32 CFR 636.5 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... INSTALLATIONS) Fort Stewart, Georgia § 636.5 Army administrative actions against intoxicated drivers. For...

  4. 32 CFR 636.5 - Army administrative actions against intoxicated drivers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY... INSTALLATIONS) Fort Stewart, Georgia § 636.5 Army administrative actions against intoxicated drivers. For...

  5. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless...

  6. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless...

  7. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless...

  8. 42 CFR 93.404 - Findings of research misconduct and proposed administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... administrative actions. After completing its review, ORI either closes the case without a finding of research... administrative actions based on the record of the research misconduct proceedings and any other information... 42 Public Health 1 2010-10-01 2010-10-01 false Findings of research misconduct and...

  9. 42 CFR 93.404 - Findings of research misconduct and proposed administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... administrative actions. After completing its review, ORI either closes the case without a finding of research... administrative actions based on the record of the research misconduct proceedings and any other information... 42 Public Health 1 2011-10-01 2011-10-01 false Findings of research misconduct and...

  10. Response to Agencywide Crisis: A Model for Administrative Action.

    ERIC Educational Resources Information Center

    Alwon, Floyd J.

    1980-01-01

    Guidelines are suggested whereby mental health agency administrators can promote organizational growth and avoid dangers during an agency crisis. Emphasis is placed on the administrator's comprehension of leadership styles and task organization. Typical staff reactions to agency crises are described. (Author/DB)

  11. Nursing Academic Administrators' Lived Experiences With Incivility and Bullying From Faculty: Consequences and Outcomes Demanding Action.

    PubMed

    LaSala, Kathleen B; Wilson, Vicki; Sprunk, Elizabeth

    2016-01-01

    There are an increasing number of nursing academic administrators who identify themselves as victims of faculty incivility. This study examined experiences that academic administrators encountered with faculty incivility using a phenomenological research design. Three major themes emerged: faculty inappropriate behaviors, consequences of faculty behaviors on administrator targets, and administrators call for action. Findings revealed that incivility had devastating effects on administrators personally and professionally. PMID:26673315

  12. 15 CFR 922.50 - Appeals of administrative action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Administrator for Ocean Services and Coastal Zone Management, NOAA 1305 East-West Highway, 13th Floor, Silver... reasons (see subpart D of 15 CFR part 904 for applicable procedures), an applicant for, or a holder of,...

  13. 25 CFR 41.6 - HHS participation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GRANTS TO TRIBALLY CONTROLLED COMMUNITY COLLEGES AND NAVAJO COMMUNITY COLLEGE Tribally Controlled Community Colleges § 41.6 HHS participation. The Assistant... Education, Department of Health and Human Services, and to revise such agreement as necessary, to assist...

  14. 41 CFR 105-60.305-12 - Administrative actions to improve assessment and collection of fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Administrative actions... and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 60-PUBLIC AVAILABILITY OF AGENCY RECORDS...

  15. 14 CFR 414.41 - Administrative law judge's recommended decision in safety approval actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Administrative law judge's recommended decision in safety approval actions. 414.41 Section 414.41 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS Appeal Procedures § 414.41 Administrative law...

  16. 14 CFR 414.41 - Administrative law judge's recommended decision in safety approval actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Administrative law judge's recommended decision in safety approval actions. 414.41 Section 414.41 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS Appeal Procedures § 414.41 Administrative law...

  17. 14 CFR 414.41 - Administrative law judge's recommended decision in safety approval actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Administrative law judge's recommended decision in safety approval actions. 414.41 Section 414.41 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS Appeal Procedures § 414.41 Administrative law...

  18. 14 CFR 414.41 - Administrative law judge's recommended decision in safety approval actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Administrative law judge's recommended decision in safety approval actions. 414.41 Section 414.41 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS Appeal Procedures § 414.41 Administrative law...

  19. Patricia Hartge Receives the HHS Career Achievement Award

    Cancer.gov

    In February 2012, Patricia Hartge, Sc.D., Deputy Director of DCEG’s Epidemiology and Biostatistics Program, received the Department of Health and Human Services (HHS) Career Achievement Award at the HHS Honor Awards Ceremony.

  20. 75 FR 3479 - Mortgagee Review Board: Administrative Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... Whitaker Mortgage Corporation, Ocala, FL [Docket No. 09-9607-MR] Action: On August 4, 2009, the Board immediately suspended Taylor, Bean and Whitaker Mortgage Corporation's (Taylor, Bean and Whitaker) FHA... HUD: Taylor, Bean and Whitaker failed to timely file an annual audit report and audited...

  1. 48 CFR 302.7100 - HHS standard templates and formats.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false HHS standard templates and formats. 302.7100 Section 302.7100 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL DEFINITIONS OF WORDS AND TERMS HHS Standard Templates and Formats 302.7100 HHS standard...

  2. 48 CFR 302.7100 - HHS standard templates and formats.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false HHS standard templates and formats. 302.7100 Section 302.7100 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL DEFINITIONS OF WORDS AND TERMS HHS Standard Templates and Formats 302.7100 HHS standard...

  3. 48 CFR 302.7100 - HHS standard templates and formats.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false HHS standard templates and formats. 302.7100 Section 302.7100 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL DEFINITIONS OF WORDS AND TERMS HHS Standard Templates and Formats 302.7100 HHS standard...

  4. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to...

  5. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to...

  6. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to...

  7. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to...

  8. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to...

  9. 40 CFR 97.428 - Administrator's action on submissions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS TR NOX Annual... conduct independent audits concerning any submission under the TR NOX Annual Trading Program and make appropriate adjustments of the information in the submission. (b) The Administrator may deduct TR NOX...

  10. 40 CFR 97.428 - Administrator's action on submissions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS TR NOX Annual... conduct independent audits concerning any submission under the TR NOX Annual Trading Program and make appropriate adjustments of the information in the submission. (b) The Administrator may deduct TR NOX...

  11. 40 CFR 97.428 - Administrator's action on submissions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS TR NOX Annual... conduct independent audits concerning any submission under the TR NOX Annual Trading Program and make appropriate adjustments of the information in the submission. (b) The Administrator may deduct TR NOX...

  12. 32 CFR 513.3 - Administrative and punitive actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...)). (2) Denial of reenlistment (enlisted members) (AR 601-280). (3) Administrative separation from the Service (AR 635-100 or AR 635-200). (4) Punishment under the UCMJ. (See § 513.1(e)(7).) (b) Official... with debt complaints will be filed per AR 600-37 and the Army Functional Files System (AR 340-2 and...

  13. 32 CFR 513.3 - Administrative and punitive actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...)). (2) Denial of reenlistment (enlisted members) (AR 601-280). (3) Administrative separation from the Service (AR 635-100 or AR 635-200). (4) Punishment under the UCMJ. (See § 513.1(e)(7).) (b) Official... with debt complaints will be filed per AR 600-37 and the Army Functional Files System (AR 340-2 and...

  14. 32 CFR 513.3 - Administrative and punitive actions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...)). (2) Denial of reenlistment (enlisted members) (AR 601-280). (3) Administrative separation from the Service (AR 635-100 or AR 635-200). (4) Punishment under the UCMJ. (See § 513.1(e)(7).) (b) Official... with debt complaints will be filed per AR 600-37 and the Army Functional Files System (AR 340-2 and...

  15. 78 FR 2997 - Administration on Intellectual and Developmental Disabilities (AIDD); Notice of Meeting via...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... Intellectual Disabilities (PCPID), HHS. ACTION: Notice of Meeting via Conference Call. DATES: Wednesday... Committee for People with Intellectual Disabilities, 200 Independence Avenue, SW., Room 637D, Washington, DC... Services, through the Administration on Intellectual and Developmental Disabilities, on a broad range...

  16. 78 FR 11654 - Draft Guidance for Industry and Food and Drug Administration Staff; Providing Information About...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... Food, Drug, and Cosmetic Act; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Pediatric Uses of Medical Devices Under Section 515A of the Federal Food, Drug, and Cosmetic Act.'' FDA is... information required under the Federal Food, Drug, and Cosmetic Act (the FD&C Act). This draft guidance is...

  17. 77 FR 26768 - Food and Drug Administration/International Society for Pharmaceutical Engineering Cosponsorship...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ..., and Sustaining a Culture of Compliance AGENCY: Food and Drug Administration, HHS. ] ACTION: Notice of... Culture of Compliance.'' DATES: Date and Time: The public workshop will be held on June 4, 2012, 9 a.m. to.... Topics for discussion include the following: (1) The Business Case For Change; (2) Quality...

  18. 75 FR 57963 - Draft Guidance for Industry and Food and Drug Administration Staff; Establishing the Performance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... Helicobacter pylori; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food... detecting Helicobacter pylori (H. pylori). This draft guidance is not final nor is it in effect at this time... Detection of Antibodies to Helicobacter pylori,'' to suggest information that submitters provide that...

  19. 76 FR 72951 - Guidance for Industry and Food and Drug Administration Staff; Establishing the Performance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... (74 FR 46433), FDA announced the availability of the draft guidance. Comments on the draft guidance... Differentiation of Human Papillomaviruses; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Differentiation of Human Papillomaviruses.'' This guidance document provides industry and Agency staff...

  20. 40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the...

  1. 40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the...

  2. 40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the...

  3. 40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the...

  4. 40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the...

  5. 21 CFR 1316.93 - Ruling on petition for expedited release in an administrative forfeiture action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Ruling on petition for expedited release in an administrative forfeiture action. 1316.93 Section 1316.93 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION... commercial fishing industry vessel for which a summons has been issued shall dismiss the summons),...

  6. 42 CFR 457.203 - Administrative and judicial review of action on State plan material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Administrative and judicial review of action on State plan material. 457.203 Section 457.203 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES...; Deferral and Disallowance of Claims; Reduction of Federal Medical Payments § 457.203 Administrative...

  7. 20 CFR 658.702 - Initial action by the Regional Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... LABOR ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Federal Application of Remedial Action... repayment or withhold future funds in the amount in question. If the Regional Administrator disallows costs... the acceptance of an offer of a hearing, however, shall not stay the effectiveness of the...

  8. 21 CFR 1316.94 - Posting of substitute res in an administrative forfeiture action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Posting of substitute res in an administrative forfeiture action. 1316.94 Section 1316.94 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF... property if it is not evidence of a violation of law or has design or other characteristics...

  9. 14 CFR § 1240.110 - Recommendation to, and action by, the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Recommendation to, and action by, the Administrator. § 1240.110 Section § 1240.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INVENTIONS AND CONTRIBUTIONS Awards for Scientific and Technical Contributions...

  10. 14 CFR 1240.110 - Recommendation to, and action by, the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Recommendation to, and action by, the Administrator. 1240.110 Section 1240.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INVENTIONS AND CONTRIBUTIONS Awards for Scientific and Technical Contributions § 1240.110 Recommendation...

  11. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular...

  12. 40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular...

  13. 14 CFR 414.41 - Administrative law judge's recommended decision in safety approval actions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Administrative law judge's recommended decision in safety approval actions. 414.41 Section 414.41 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS...

  14. 75 FR 70271 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Pressure Wound Therapy; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... Pressure Wound Therapy (NPWT).'' This guidance document describes a means by which non-powered suction... Device Intended for Negative Pressure Wound Therapy (NPWT)'' to the Division of Small...

  15. 76 FR 5387 - Guidance for Industry and Food and Drug Administration Staff; “`Harmful and Potentially Harmful...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    .... SUPPLEMENTARY INFORMATION: I. Background In the Federal Register of June 10, 2010 (75 FR 32952), FDA announced... Food, Drug, and Cosmetic Act''; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Section 904(e) of the Federal Food, Drug, and Cosmetic Act.'' This guidance provides written guidance...

  16. 75 FR 69089 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... for the Topical Approximation of Skin; Availability AGENCY: Food and Drug Administration, HHS. ACTION... Intended for the Topical Approximation of Skin.'' This guidance document describes a means by which tissue adhesives with adjunct wound closure devices intended for the topical approximation of skin may comply...

  17. 78 FR 100 - Guidance for Industry and Food and Drug Administration Staff; Refuse To Accept Policy for 510(k)s...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... checklists for use by FDA review staff. In the Federal Register of August 13, 2012 (77 FR 48159), FDA...; Refuse To Accept Policy for 510(k)s; Availability AGENCY: Food and Drug Administration, HHS. ACTION... entitled ``Refuse to Accept Policy for 510(k)s.'' The purpose of this document is to explain the...

  18. 49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HIGHWAY-RAIL GRADE CROSSINGS Exceptions to the Use of the Locomotive Horn Silenced Horns at Groups of Crossings-Quiet Zones § 222.57 Can parties seek review of the Associate Administrator's actions? (a) A... to temporarily cease sounding of the locomotive horn over public highway-rail grade crossings for...

  19. 49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... HIGHWAY-RAIL GRADE CROSSINGS Exceptions to the Use of the Locomotive Horn Silenced Horns at Groups of Crossings-Quiet Zones § 222.57 Can parties seek review of the Associate Administrator's actions? (a) A... to temporarily cease sounding of the locomotive horn over public highway-rail grade crossings for...

  20. 49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... HIGHWAY-RAIL GRADE CROSSINGS Exceptions to the Use of the Locomotive Horn Silenced Horns at Groups of Crossings-Quiet Zones § 222.57 Can parties seek review of the Associate Administrator's actions? (a) A... to temporarily cease sounding of the locomotive horn over public highway-rail grade crossings for...

  1. 49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... HIGHWAY-RAIL GRADE CROSSINGS Exceptions to the Use of the Locomotive Horn Silenced Horns at Groups of Crossings-Quiet Zones § 222.57 Can parties seek review of the Associate Administrator's actions? (a) A... to temporarily cease sounding of the locomotive horn over public highway-rail grade crossings for...

  2. 49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... HIGHWAY-RAIL GRADE CROSSINGS Exceptions to the Use of the Locomotive Horn Silenced Horns at Groups of Crossings-Quiet Zones § 222.57 Can parties seek review of the Associate Administrator's actions? (a) A... to temporarily cease sounding of the locomotive horn over public highway-rail grade crossings for...

  3. Action Research as a Professional Development Tool for Teachers and Administrators

    ERIC Educational Resources Information Center

    Campbell, Christine; Tovar, Deanna

    2006-01-01

    Many teachers and administrators would acknowledge there are areas of concern in their classrooms and schools. Whether termed "problems," "issues," "challenges," or, as Nunan (1994) put it "puzzles," they provide committed professionals with an opportunity to improve the status quo. Action research is one…

  4. 42 CFR 430.18 - Administrative review of action on State plan material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Administrative review of action on State plan material. 430.18 Section 430.18 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS GRANTS TO STATES FOR MEDICAL...

  5. 40 CFR 78.6 - Action on petition for administrative review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Action on petition for administrative review. 78.6 Section 78.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... evidentiary hearing concerning the petition for review is requested or is to be held, the...

  6. Attitudes of Faculty and Administrators Toward Affirmative Action in Higher Education; A Second Look.

    ERIC Educational Resources Information Center

    Maca, Suanne D.

    This dissertation investigated six indications of change regarding affirmative action efforts on the University of Texas at Austin campus since December, 1973. These indications of change were recorded in university personnel documents, EEO/AA Office records, and the results of a questionnaire submitted to the faculty and administrators of the…

  7. 45 CFR 605.0 - Adoption of HHS regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human Services on Nondiscrimination on the Basis of Handicap, 45 CFR part 84, including any amendments thereto... 45 Public Welfare 3 2013-10-01 2013-10-01 false Adoption of HHS regulations. 605.0 Section...

  8. 45 CFR 605.0 - Adoption of HHS regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human Services on Nondiscrimination on the Basis of Handicap, 45 CFR part 84, including any amendments thereto... 45 Public Welfare 3 2012-10-01 2012-10-01 false Adoption of HHS regulations. 605.0 Section...

  9. 45 CFR 605.0 - Adoption of HHS regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human Services on Nondiscrimination on the Basis of Handicap, 45 CFR part 84, including any amendments thereto... 45 Public Welfare 3 2014-10-01 2014-10-01 false Adoption of HHS regulations. 605.0 Section...

  10. 45 CFR 605.0 - Adoption of HHS regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human Services on Nondiscrimination on the Basis of Handicap, 45 CFR part 84, including any amendments thereto... 45 Public Welfare 3 2011-10-01 2011-10-01 false Adoption of HHS regulations. 605.0 Section...

  11. 45 CFR 605.0 - Adoption of HHS regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human Services on Nondiscrimination on the Basis of Handicap, 45 CFR part 84, including any amendments thereto... 45 Public Welfare 3 2010-10-01 2010-10-01 false Adoption of HHS regulations. 605.0 Section...

  12. 78 FR 5182 - Annual Update of the HHS Poverty Guidelines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty Guidelines AGENCY: Department of... Health and Human Services (HHS) poverty guidelines to account for last calendar year's increase in prices... Federal, state, or local office that is responsible for that program. For information about...

  13. 77 FR 4034 - Annual Update of the HHS Poverty Guidelines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-26

    ... HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty Guidelines AGENCY: Department of... Health and Human Services (HHS) poverty guidelines to account for last calendar year's increase in prices... Federal, state, or local office that is responsible for that program. For information about...

  14. 76 FR 3637 - Annual Update of the HHS Poverty Guidelines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ... was delayed, as described at 75 FR 45628. However, the level of the 2011 poverty guidelines presented... HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty Guidelines AGENCY: Department of... Health and Human Services (HHS) poverty guidelines to account for last calendar year's increase in...

  15. 42 CFR 1007.21 - Other applicable HHS regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG AUTHORITIES STATE MEDICAID FRAUD CONTROL UNITS § 1007.21 Other applicable HHS regulations. Except as otherwise provided in this part,...

  16. 42 CFR 1007.21 - Other applicable HHS regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG AUTHORITIES STATE MEDICAID FRAUD CONTROL UNITS § 1007.21 Other applicable HHS regulations. Except as otherwise provided in this part,...

  17. The relative advantages of criminal versus administrative environmental enforcement actions in Israel.

    PubMed

    Tal, Alon; Aharon, Yaara; Yuhas-Peled, Hadar

    2010-04-01

    Most environmental enforcement programs have separate criminal and administrative procedures for addressing violations. Pitting "criminal"versus"administrative" enforcement as mutually exclusive alternatives constitutes a "false dilemma". Clearly, the government response should be influenced by the severity of pollution and the specific circumstances of the polluter. Yet, policy makers seeking to improve environmental compliance need to have a clearer picture about the merits of each approach and their relative effectiveness. This research empirically assesses the effectiveness of criminal versus administrative enforcement activities in Israel. After considering the philosophical implications associated with each regulatory approach, the results of a year-long study are presented. A series of performance indicators are utilized, with particular weight on compliance status in the field, to assess the condition of environmental violations several years subsequent to completion of enforcement activities. The state of 100 violations of air, water and hazardous materials laws that had been addressed through the criminal process were matched with results of comparable violations, against which administrative actions were taken. Results suggest that while criminal enforcement is a longer process, compliance following these actions was significantly greater than in administrative enforcement cases. The findings also underline the significance of a systematic follow-up system for tracking violations after enforcement actions are complete. Finally, the study confirms the benefits of targeted assistance to improve compliance among violators of environmental standards.

  18. 42 CFR 93.406 - Final HHS actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct...

  19. 40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise...

  20. 40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise...

  1. 40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise...

  2. 40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise...

  3. 40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise...

  4. 40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the...

  5. 40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the...

  6. 40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the...

  7. 40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the...

  8. 40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the...

  9. Electroporation-delivered transdermal neostigmine in rats: equivalent action to intravenous administration

    PubMed Central

    Berkó, Szilvia; Szűcs, Kálmán F; Balázs, Boglárka; Csányi, Erzsébet; Varju, Gábor; Sztojkov-Ivanov, Anita; Budai-Szűcs, Mária; Bóta, Judit; Gáspár, Róbert

    2016-01-01

    Purpose Transdermal electroporation has become one of the most promising noninvasive methods for drug administration, with greatly increased transport of macromolecules through the skin. The cecal-contracting effects of repeated transdermal electroporation delivery and intravenous administration of neostigmine were compared in anesthetized rats. Methods The cecal contractions were detected with implantable strain gauge sensors, and the plasma levels of neostigmine were followed by high-performance liquid chromatography. Results Both intravenously and EP-administered neostigmine (0.2–66.7 μg/kg) increased the cecal contractions in a dose-dependent manner. For both the low doses and the highest dose, the neostigmine plasma concentrations were the same after the two modes of administration, while an insignificantly higher level was observed at a dose of 20 μg/kg after intravenous administration as compared with the electroporation route. The contractile responses did not differ significantly after the two administration routes. Conclusion The results suggest that electroporation-delivered neostigmine elicits action equivalent to that observed after intravenous administration as concerning both time and intensity. Electroporation permits the delivery of even lower doses of water-soluble compounds through the skin, which is very promising for clinical practice. PMID:27274203

  10. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... have been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria..., and Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the...

  11. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... have been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria..., and Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the...

  12. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria are...) Genetic Elements, Recombinant and/or Synthetic Nucleic Acids, and Recombinant and/or Synthetic...

  13. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... have been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria..., and Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the...

  14. 78 FR 56706 - HHS Retrospective Review 2013 Request for Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... to: Promote economic growth, innovation, competitiveness, and job creation; Reduce regulatory and... that would be appropriate for review. See 76 FR 32330 (June 6, 2011). HHS has made significant...

  15. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... GS-1102s and GS-1105s are required to complete both HHS University's classroom-based and on-line... administer acquisitions that involve electronic information technology (EIT) products or services (subject...

  16. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... GS-1102s and GS-1105s are required to complete both HHS University's classroom-based and on-line... administer acquisitions that involve electronic information technology (EIT) products or services (subject...

  17. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... GS-1102s and GS-1105s are required to complete both HHS University's classroom-based and on-line... administer acquisitions that involve electronic information technology (EIT) products or services (subject...

  18. Investigation of the mechanisms of action behind Electromotive Drug Administration (EMDA)

    PubMed Central

    Vásquez, Juan Luis; Miklavčič, Damijan; Hermann, Gregers G.G.; Gehl, Julie

    2016-01-01

    Objective Bladder cancer is a cause of considerable morbidity worldwide. Electromotive Drug Administration is a method that combines intravesical chemotherapy with local electric field application. Electroporation has been suggested among other mechanisms as having a possible role in the therapy, so the goal of the present study was to investigate the electric fields present in the bladder wall during the treatment to determine which mechanisms might be involved. Material and Methods Electromotive Drug Administration involves applying intravesical mitomycin C with direct current of 20 mA delivered through a catheter electrode for 30 min. For numerical electric field computation we built a 3-D nonhomogeneous patient specific model based on CT images and used finite element method simulations to determine the electric fields in the whole body. Results Results indicate that highest electric field in the bladder wall was 37.7 V/m. The mean electric field magnitude in the bladder wall was 3.03 V/m. The mean magnitude of the current density in the bladder wall was 0.61 A/m2. Conclusions The present study shows that electroporation is not the mechanism of action in EMDA. A more likely explanation of the mechanism of action is iontophoretic forces increasing the mitomycin C concentration in the bladder wall. PMID:27635313

  19. Investigation of the mechanisms of action behind Electromotive Drug Administration (EMDA)

    PubMed Central

    Vásquez, Juan Luis; Miklavčič, Damijan; Hermann, Gregers G.G.; Gehl, Julie

    2016-01-01

    Objective Bladder cancer is a cause of considerable morbidity worldwide. Electromotive Drug Administration is a method that combines intravesical chemotherapy with local electric field application. Electroporation has been suggested among other mechanisms as having a possible role in the therapy, so the goal of the present study was to investigate the electric fields present in the bladder wall during the treatment to determine which mechanisms might be involved. Material and Methods Electromotive Drug Administration involves applying intravesical mitomycin C with direct current of 20 mA delivered through a catheter electrode for 30 min. For numerical electric field computation we built a 3-D nonhomogeneous patient specific model based on CT images and used finite element method simulations to determine the electric fields in the whole body. Results Results indicate that highest electric field in the bladder wall was 37.7 V/m. The mean electric field magnitude in the bladder wall was 3.03 V/m. The mean magnitude of the current density in the bladder wall was 0.61 A/m2. Conclusions The present study shows that electroporation is not the mechanism of action in EMDA. A more likely explanation of the mechanism of action is iontophoretic forces increasing the mitomycin C concentration in the bladder wall.

  20. Administrators in Action--Managing Public Monies and Processing Emotion in School Activities: A Teaching Case Study

    ERIC Educational Resources Information Center

    Tenuto, Penny L.; Gardiner, Mary E.; Yamamoto, Julie K.

    2015-01-01

    This teaching case describes school administrators in action performing day-to-day leadership tasks, managing public funds in school activities, and interacting with others appropriately. The case focuses on administrative challenges in handling and managing school activity funds. A method for processing emotion is discussed to assist…

  1. [The protective action of tocopherol acetate in simultaneous administration with nitrobenzene and its chloro derivatives].

    PubMed

    Paranich, A V; Paranich, L I; Bugaĭ, E V; Ortis, L F

    1998-05-01

    In experiments in albino rats, effects were studied of nitrobenzene and its chloro derivatives in intragastric administration with tocoferolum acetatum. Changes in the process of lipid peroxidation in blood serum, liver, and spleen which were characteristic of xenobiotics themselves have been shown to be less pronounced in this setting. Tocoferolum acetatum being administered at the same time is actively drawn into the metabolism. Normalization of the antioxidant activity of the tissues under investigation was to be observed, with lipid peroxidation and the antioxidant system being in equilibrium. Tocoferolum acetatum administered with xenobiotics has been shown to have a protective action. Tocoferolum acetatum is recommended to be included into diets for workers engaged in chemical industry on a prophylactic basis.

  2. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria are...) Genetic Elements, Recombinant and/or Synthetic Nucleic Acids, and Recombinant and/or Synthetic Organisms... exclusion category. (e) An attenuated strain of a select agent or a select toxin modified to be less...

  3. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... located at Parts 1-1299 of Title 21. • Procurement (contract) regulations are located at Chapter 3 of Title 41. Each volume of the Code contains an index of its parts. (5 U.S.C. 301) ... titles of the Code of Federal Regulations: • Regulations having HHS-wide application or which the...

  4. 42 CFR 93.227 - Secretary or HHS.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  5. 42 CFR 93.227 - Secretary or HHS.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  6. 42 CFR 93.227 - Secretary or HHS.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  7. 42 CFR 93.227 - Secretary or HHS.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  8. 42 CFR 93.227 - Secretary or HHS.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  9. HHS announces Text4Health task force recommendations

    Cancer.gov

    Today, the U.S. Department of Health and Human Services (HHS) announced new recommendations to support health text messaging and mobile health (mHealth) programs. The department has been actively exploring means to capitalize on the rapid proliferation of

  10. 42 CFR 1007.21 - Other applicable HHS regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OIG AUTHORITIES STATE MEDICAID FRAUD CONTROL UNITS § 1007.21 Other applicable HHS regulations. Except as otherwise provided in this part, the following regulations from 45 CFR subtitle A apply to grants... Procedure for Hearings Under 45 CFR part 80; Part 84—Nondiscrimination on the Basis of Handicap in...

  11. 42 CFR 1007.21 - Other applicable HHS regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OIG AUTHORITIES STATE MEDICAID FRAUD CONTROL UNITS § 1007.21 Other applicable HHS regulations. Except as otherwise provided in this part, the following regulations from 45 CFR subtitle A apply to grants... Procedure for Hearings Under 45 CFR part 80; Part 84—Nondiscrimination on the Basis of Handicap in...

  12. 42 CFR 1007.21 - Other applicable HHS regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OIG AUTHORITIES STATE MEDICAID FRAUD CONTROL UNITS § 1007.21 Other applicable HHS regulations. Except as otherwise provided in this part, the following regulations from 45 CFR subtitle A apply to grants... Procedure for Hearings Under 45 CFR part 80; Part 84—Nondiscrimination on the Basis of Handicap in...

  13. 42 CFR 93.500 - General policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General... findings of research misconduct and HHS administrative actions, including debarment or suspension, arising... to contest ORI research misconduct findings and HHS administrative actions under this part,...

  14. 42 CFR 93.500 - General policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General... findings of research misconduct and HHS administrative actions, including debarment or suspension, arising... to contest ORI research misconduct findings and HHS administrative actions under this part,...

  15. Possession, Use, and Transfer of Select Agents and Toxins-- Addition of Bacillus Cereus Biovar Anthracis to the HHS List of Select Agents and Toxins. Interim final rule and request for comments.

    PubMed

    2016-09-14

    The Centers for Disease Control and Prevention (CDC) in the Department of Health and Human Services (HHS) is adding Bacillus cereus Biovar anthracis to the list of HHS select agents and toxins as a Tier 1 select agent. We are taking this action to regulate this agent that is similar to B. anthracis to prevent its misuse, which could cause a biological threat to public health and/or national security. PMID:27632805

  16. Possession, Use, and Transfer of Select Agents and Toxins-- Addition of Bacillus Cereus Biovar Anthracis to the HHS List of Select Agents and Toxins. Interim final rule and request for comments.

    PubMed

    2016-09-14

    The Centers for Disease Control and Prevention (CDC) in the Department of Health and Human Services (HHS) is adding Bacillus cereus Biovar anthracis to the list of HHS select agents and toxins as a Tier 1 select agent. We are taking this action to regulate this agent that is similar to B. anthracis to prevent its misuse, which could cause a biological threat to public health and/or national security.

  17. 42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if...

  18. 42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if...

  19. 42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if...

  20. One Department Serving Rural America: HHS Rural Task Force Report to the Secretary.

    ERIC Educational Resources Information Center

    Department of Health and Human Services, Washington, DC.

    In 2001, the Department of Health and Human Services (HHS) created a rural task force to develop strategies to improve HHS services in rural communities. Fifteen HHS agencies have programs serving rural communities; child- and education-related programs provide child welfare services, Head Start, health promotion and prevention services, training…

  1. 45 CFR 91.18 - Age distinctions contained in HHS regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Age distinctions contained in HHS regulations. 91... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.18 Age distinctions contained in HHS regulations. Any...

  2. 45 CFR 91.18 - Age distinctions contained in HHS regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Age distinctions contained in HHS regulations. 91... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.18 Age distinctions contained in HHS regulations. Any...

  3. 45 CFR 91.18 - Age distinctions contained in HHS regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Age distinctions contained in HHS regulations. 91... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.18 Age distinctions contained in HHS regulations. Any...

  4. 45 CFR 91.18 - Age distinctions contained in HHS regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Age distinctions contained in HHS regulations. 91... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.18 Age distinctions contained in HHS regulations. Any...

  5. Improved insulin response and action by chronic magnesium administration in aged NIDDM subjects.

    PubMed

    Paolisso, G; Sgambato, S; Pizza, G; Passariello, N; Varricchio, M; D'Onofrio, F

    1989-04-01

    In eight aged non-insulin-dependent diabetes mellitus (NIDDM) subjects, insulin response and action were studied before and after chronic magnesium supplementation (2 g/day) to diet. Chronic magnesium supplementation to diet versus placebo produced 1) a significant increase in plasma (0.83 +/- 0.05 vs. 0.78 +/- 0.06 mM, P less than .05) and erythrocyte (2.03 +/- 0.06 vs. 1.88 +/- 0.09 mM, P less than .01) magnesium levels, 2) an increase in acute insulin response (AIR) (4.0 +/- 0.6 vs. -1.6 +/- 0.6 mU/L, P less than .05) to glucose pulse, and 3) an increase in glucose infusion rate (GIR) (3.6 +/- 0.6 vs. 2.9 +/- 0.5 mg.kg-1.min-1, P less than .025) calculated in the last 60 min of a euglycemic-hyperinsulinemic (100 mU.m2.min-1 during 180 min) glucose clamp. Net increase in AIR, glucose disappearance rate after glucose pulse, and GIR were significantly and positively correlated to the net increase in erythrocyte magnesium content calculated after chronic magnesium supplementation to diet. In conclusion, our data suggest that NIDDM subjects may benefit from therapeutic chronic administration of magnesium salts.

  6. Blood pressure-lowering effect and duration of action of bedtime administration of doxazosin determined by home blood pressure measurement.

    PubMed

    Gonokami, Kenta; Obara, Taku; Kobayashi, Mitsuru; Katada, Sakiko; Hara, Azusa; Metoki, Hirohito; Asayama, Kei; Kikuya, Masahiro; Ohkubo, Takayoshi; Imai, Yutaka

    2010-01-01

    The effects and duration of action of bedtime administration of doxazosin 2 mg for 4 weeks on uncontrolled morning home hypertension were investigated. Morning home blood pressure (HBP) was significantly lowered by bedtime administration of doxazosin. Doxazosin significantly lowered evening HBP only in the subgroup of patients with an uncontrolled evening HBP. The evening (E)/morning (M) ratio was greater in patients with an uncontrolled evening HBP than in those with a controlled evening HBP. The results suggest that bedtime administration of doxazosin effectively suppresses morning HBP in uncontrolled morning hypertensives and lowers evening HBP in uncontrolled evening hypertensives.

  7. 21 CFR 1316.92 - Petition for expedited release in an administrative forfeiture action.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Administration (DEA) or Federal Bureau of Investigation (FBI) field office in the judicial district in which the... the Director of the FBI or to the Administrator of the DEA, depending upon which agency seized...

  8. 20 CFR 408.1004 - Which administrative actions are not initial determinations?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... refund offset procedure. (See § 408.943). (i) The determination to reduce, suspend, or terminate...

  9. 20 CFR 408.1004 - Which administrative actions are not initial determinations?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... refund offset procedure. (See § 408.943). (i) The determination to reduce, suspend, or terminate...

  10. 20 CFR 408.1004 - Which administrative actions are not initial determinations?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... refund offset procedure. (See § 408.943). (i) The determination to reduce, suspend, or terminate...

  11. 20 CFR 408.1004 - Which administrative actions are not initial determinations?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... refund offset procedure. (See § 408.943). (i) The determination to reduce, suspend, or terminate...

  12. 20 CFR 408.1004 - Which administrative actions are not initial determinations?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... refund offset procedure. (See § 408.943). (i) The determination to reduce, suspend, or terminate...

  13. Human drugs and biologics; determination that informed consent is NOT feasible or is contrary to the best interests of recipients; revocation of 1990 interim final rule; establishment of new interim final rule. Food and Drug Administration, HHS. Interim final rule; opportunity for public comment.

    PubMed

    1999-10-01

    The Food and Drug Administration (FDA) is revoking its 1990 interim final regulations that permitted the Commissioner of Food and Drugs (the Commissioner) to determine that obtaining informed consent from military personnel for the use of an investigational drug or biologic is not feasible in certain situations related to military combat. FDA also is issuing a new interim final rule addressing waiver of informed consent in military operations. FDA is taking these actions based on its analysis and consideration of all relevant facts, including its evaluation of the Department of Defense's (DOD) experience during the Persian Gulf War, its evaluation of the comments received by the agency in response to the agency's July 31, 1997, request for comments on whether the agency should revise or revoke the interim regulations, and the enactment of the Strom Thurmond National Defense Authorization Act for Fiscal Year 1999 (the Defense Authorization Act). Under the Defense Authorization Act, the President is authorized to waive the Federal Food, Drug, and Cosmetic Act's (the act) informed consent requirements in military operations if the President finds that obtaining consent is infeasible or contrary to the best interests of recipients and on an additional ground that obtaining consent is contrary to national security interests. In light of the enactment of the Defense Authorization Act, with an immediate effective date, and because the President could be called upon to make a waiver determination for military personnel engaged in a specific military operation at any time, the agency believes that it is critical to have in place adequate criteria and standards for the President to apply in making an informed consent waiver determination. Therefore, FDA is issuing a new interim final regulation with an immediate effective date to establish criteria and standards for the President to apply in making a determination that informed consent is not feasible or is contrary to the

  14. 20 CFR 410.610 - Administrative actions that are initial determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... determinations. 410.610 Section 410.610 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE... Determinations, Administrative Review, Finality of Decisions, and Representation of Parties § 410.610... individual has been made (see § 410.561). (l) Need for representative payment. The Social...

  15. 20 CFR 410.610 - Administrative actions that are initial determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... determinations. 410.610 Section 410.610 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE... Determinations, Administrative Review, Finality of Decisions, and Representation of Parties § 410.610... individual has been made (see § 410.561). (l) Need for representative payment. The Social...

  16. 20 CFR 410.615 - Administrative actions that are not initial determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... determinations. 410.615 Section 410.615 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE... Determinations, Administrative Review, Finality of Decisions, and Representation of Parties § 410.615... following: (a) The suspension of benefits pursuant to the criteria in section 203(h)(3) of the...

  17. 20 CFR 410.615 - Administrative actions that are not initial determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... determinations. 410.615 Section 410.615 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE... Determinations, Administrative Review, Finality of Decisions, and Representation of Parties § 410.615... following: (a) The suspension of benefits pursuant to the criteria in section 203(h)(3) of the...

  18. 20 CFR 658.702 - Initial action by the Regional Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LABOR (CONTINUED) ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Federal Application of... repayment or withhold future funds in the amount in question. If the Regional Administrator disallows costs... the acceptance of an offer of a hearing, however, shall not stay the effectiveness of the...

  19. 20 CFR 658.702 - Initial action by the Regional Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... LABOR (CONTINUED) ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Federal Application of... repayment or withhold future funds in the amount in question. If the Regional Administrator disallows costs... the acceptance of an offer of a hearing, however, shall not stay the effectiveness of the...

  20. Streamlining Administrative Procedures at the Defense Language Institute: The Strategic Impact Model in Action

    ERIC Educational Resources Information Center

    Oded, Yaniv; Su, Bude

    2010-01-01

    Performance at the Defense Language Institute was examined through the prism of human performance technology and the strategic impact model. This examination revealed performance deficiencies in the administrative realm that required mainly a noninstructional intervention. A systematic analysis showed that digitizing administrative procedures…

  1. 26 CFR 301.7430-8 - Administrative costs incurred in damage actions for violations of section 362 or 524 of the...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 18 2011-04-01 2011-04-01 false Administrative costs incurred in damage actions for violations of section 362 or 524 of the Bankruptcy Code. 301.7430-8 Section 301.7430-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION...

  2. Study on Interactions between the Major Apple Valsa Canker Pathogen Valsa mali and Its Biocontrol Agent Saccharothrix yanglingensis Hhs.015 Using RT-qPCR

    PubMed Central

    Fan, Dongying; Li, Yanfang; Zhao, Lingyun; Li, Zhengpeng; Huang, Lili; Yan, Xia

    2016-01-01

    The mechanism of biocontrol agent Saccharothrix yanglingensis Hhs.015 action against Valsa mali, a major apple Valsa canker pathogen, was examined using a novel, sensitive (minimum detection limit 100 pg/μL) and reliably RT-qPCR technique. Prior to lesion formation, total concentration of V. mali in the bark showed a significant decrease (p<0.05) after 24 h of Hhs.015 treatment. This was more pronounced at 48 and 96 h post treatment. After lesion formation, levels of V. mali remained constant at the boundary between infected and uninfected bark tissues, although the relative expansion rate of the lesion was significantly reduced (p<0.05). Gene expression levels of endo-polygalacturonase, a marker for fungal pathogenicity, were sharply reduced while host induced resistance callose synthase levels increased significantly (p<0.05) at the boundary bark at 9 d after Hhs.015 treatment. The results showed that biocontrol agent Hhs.015 prevented infection of V. mali by inhibiting pathogen growth, down-regulating pathogenicity factor expression and inducing a high level of host resistance. PMID:27611855

  3. Study on Interactions between the Major Apple Valsa Canker Pathogen Valsa mali and Its Biocontrol Agent Saccharothrix yanglingensis Hhs.015 Using RT-qPCR.

    PubMed

    Fan, Dongying; Li, Yanfang; Zhao, Lingyun; Li, Zhengpeng; Huang, Lili; Yan, Xia

    2016-01-01

    The mechanism of biocontrol agent Saccharothrix yanglingensis Hhs.015 action against Valsa mali, a major apple Valsa canker pathogen, was examined using a novel, sensitive (minimum detection limit 100 pg/μL) and reliably RT-qPCR technique. Prior to lesion formation, total concentration of V. mali in the bark showed a significant decrease (p<0.05) after 24 h of Hhs.015 treatment. This was more pronounced at 48 and 96 h post treatment. After lesion formation, levels of V. mali remained constant at the boundary between infected and uninfected bark tissues, although the relative expansion rate of the lesion was significantly reduced (p<0.05). Gene expression levels of endo-polygalacturonase, a marker for fungal pathogenicity, were sharply reduced while host induced resistance callose synthase levels increased significantly (p<0.05) at the boundary bark at 9 d after Hhs.015 treatment. The results showed that biocontrol agent Hhs.015 prevented infection of V. mali by inhibiting pathogen growth, down-regulating pathogenicity factor expression and inducing a high level of host resistance. PMID:27611855

  4. Action!

    ERIC Educational Resources Information Center

    Senese, Joseph

    1998-01-01

    A small group of teachers at one Illinois high school is helping to effect and promote change. Through the Action Research Laboratory (ARL), teams of teachers conduct collaborative action research to improve classroom practices. Data from the first two years of the ARL indicate that teachers are eager to participate in, and have thrived in, their…

  5. Using Participatory Action Research and Photo Methods to Explore Higher Education Administration as an Emotional Endeavor

    ERIC Educational Resources Information Center

    Gonzales, Leslie D.; Rincones, Rodolfo

    2013-01-01

    In this paper, we build on Wood's (2010, 2012) recent call to consider higher education as a work place that conjures emotion among constituents, particularly positional leaders, like department chairs. Using a participatory action research and photo-enhanced methodological approach, we illustrate the emotional labor that was poured into the…

  6. Administrators' Professional Learning via Twitter: The Dissonance between Beliefs and Actions

    ERIC Educational Resources Information Center

    Cho, Vincent

    2016-01-01

    Purpose: Although there has been increasing optimism about the potential for social media platforms such as Twitter to support educators' professional learning, it is yet unclear whether such promises hold true. Accordingly, the purpose of this paper is to explore school administrators' use of Twitter for professional learning.…

  7. 20 CFR 408.1003 - Which administrative actions are initial determinations?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... payment will be made; (i) A claim for benefits under § 408.351 based on alleged misinformation; and (j... amount (i.e., a reduction, suspension, or termination) which results from a mass change as defined...

  8. 20 CFR 408.1003 - Which administrative actions are initial determinations?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... payment will be made; (i) A claim for benefits under § 408.351 based on alleged misinformation; and (j... amount (i.e., a reduction, suspension, or termination) which results from a mass change as defined...

  9. 20 CFR 408.1003 - Which administrative actions are initial determinations?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... payment will be made; (i) A claim for benefits under § 408.351 based on alleged misinformation; and (j... amount (i.e., a reduction, suspension, or termination) which results from a mass change as defined...

  10. 20 CFR 408.1003 - Which administrative actions are initial determinations?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... payment will be made; (i) A claim for benefits under § 408.351 based on alleged misinformation; and (j... amount (i.e., a reduction, suspension, or termination) which results from a mass change as defined...

  11. 20 CFR 408.1003 - Which administrative actions are initial determinations?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... CERTAIN WORLD WAR II VETERANS Determinations and the Administrative Review Process Introduction... payment will be made; (i) A claim for benefits under § 408.351 based on alleged misinformation; and (j... amount (i.e., a reduction, suspension, or termination) which results from a mass change as defined...

  12. 15 CFR 720.3 - Final decision on administrative action denying export privileges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL... Administration Regulations (15 CFR parts 730 through 774). The initial decision and order will be served on each... of Industry and Security, for review of the initial decision and order. A petition for review must...

  13. 7 CFR 246.18 - Administrative review of State agency actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR... review procedures. The State agency must develop procedures for a full administrative review of the... listed in paragraph (a)(1)(ii) of this section, the State agency must develop procedures for...

  14. 48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false FAC-C and HHS SAC certification requirements. 301.603-72 Section 301.603-72 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority,...

  15. 75 FR 45628 - Delayed Update of the HHS Poverty Guidelines for the Remainder of 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... HUMAN SERVICES Office of the Secretary Delayed Update of the HHS Poverty Guidelines for the Remainder of... delayed update of the Department of Health and Human Services (HHS) poverty guidelines for the remainder of 2010, and until the 2011 poverty guidelines are published, which is expected to occur in...

  16. 75 FR 3734 - 2009 HHS Poverty Guidelines Extended Until March 1, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... published in the Federal Register (74 FR 4199) on January 23, 2009, shall remain in effect until the... HUMAN SERVICES Office of the Secretary 2009 HHS Poverty Guidelines Extended Until March 1, 2010 AGENCY... Human Services (HHS) poverty guidelines will remain in effect until updated 2010 poverty guidelines...

  17. 75 FR 28023 - Solicitation of Written Comments on Draft HHS Strategic Framework on Multiple Chronic Conditions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... HUMAN SERVICES Solicitation of Written Comments on Draft HHS Strategic Framework on Multiple Chronic... electronically and may be addressed to MCC@hhs.gov . Written responses should be addressed to Department of... apply) and your name. Anonymous submissions will not be considered. The submission of written...

  18. 42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false HHS criteria for requesting books, documents, and... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM PROGRAM INTEGRITY: MEDICARE Access to Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and...

  19. Action of a chronic administration of mescaline in dynamic behavioural situations.

    PubMed

    Fundaro', A; Molinengo, L; Cassone, M C; Orsetti, M

    1986-01-01

    The modifications of the rat behaviour caused by a chronic administration of mescaline were studied in two schedules of operant conditioning. In the "periodic conditioning" test, the schedule of reinforcement was changed from a fixed ratio to a fixed interval schedule. Mescaline (4 mg/kg/day and 10 mg/kg/day) caused no modification of the ability of the rat to adapt its behaviour to the new experimental situation. In the "reversal test" the contingency for food delivery was switched from one lever, where responses were previously reinforced to the other lever where responses had no programmed consequences. A chronic administration of mescaline (4 mg/kg/day) caused a total incapacity of the rat to switch to the lever which became reinforced in the reversal trial. A chronic administration of 9 mg/kg/day of mescaline had an excitatory effect and the number of reinforced responses in the II and III reversals exceeded the unreinforced responses in a measure greater than in the controls.

  20. Taking Action: Ideas To Promote Technology Integration [and] Administrator's Desk Reference: Readings To Promote Technology Integration. Technology Integration: A Thematic Focus.

    ERIC Educational Resources Information Center

    Thormann, Joan, Ed.; And Others

    This guide for school administrators interested in technology integration in the curriculum was developed from discussions at the Technology Integration Seminar held in March, 1991. The guide is divided into five chapters covering various administrative responsibilities and action steps. The first chapter presents an overview and identifies…

  1. 29 CFR 102.48 - Action of the Board upon expiration of time to file exceptions to the administrative law judge's...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to file exceptions to the administrative law judge's decision; decisions by the Board; extraordinary... 29 Labor 2 2010-07-01 2010-07-01 false Action of the Board upon expiration of time to file exceptions to the administrative law judge's decision; decisions by the Board; extraordinary...

  2. 76 FR 14402 - Draft Action Plan-A Public Health Action Plan To Combat Antimicrobial Resistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... HUMAN SERVICES Centers for Disease Control and Prevention Draft Action Plan--A Public Health Action Plan...), Department of Health and Human Services (DHHS). ACTION: Notice of availability and request for public comment... Human Services (HHS) is publishing this notice requesting public comment on the draft A Public...

  3. Reduction of Tendon Adhesions following Administration of Adaprev, a Hypertonic Solution of Mannose-6-Phosphate: Mechanism of Action Studies

    PubMed Central

    Wong, Jason K. F.; Metcalfe, Anthony D.; Wong, Richard; Bush, Jim; Platt, Chris; Garcon, Arnaud; Goldspink, Nick; McGrouther, Duncan A.; Ferguson, Mark W. J.

    2014-01-01

    Repaired tendons may be complicated by progressive fibrosis, causing adhesion formation or tendon softening leading to tendon rupture and subsequent reduced range of motion. There are few therapies available which improve the gliding of damaged tendons in the hand. We investigate the role of Mannose 6-phosphate (M6P) in a 600 mM hypertonic solution (Adaprev) on tendon adhesion formation in vivo using a mouse model of severed tendon in conjunction with analysis of collagen synthesis, cellular proliferation and receptors involved in TGF beta signalling. Cytotoxicity was assessed by measuring tissue residency, mechanical strength and cell viability of tendons after treatment with Adaprev. To elicit potential modes of action, in vitro and ex vivo studies were performed investigating phosphorylation of p38, cell migration and proliferation. Adaprev treatment significantly (p<0.05) reduced the development of adhesions and improved collagen organisation without reducing overall collagen synthesis following tendon injury in vivo. The bioavailability of Adaprev saw a 40% reduction at the site of administration over 45 minutes and tendon fibroblasts tolerated up to 120 minutes of exposure without significant loss of cell viability or tensile strength. These favourable effects were independent of CI-MPR and TGF-β signalling and possibly highlight a novel mechanism of action related to cellular stress demonstrated by phosphorylation of p38. The effect of treatment reduced tendon fibroblast migration and transiently halted tendon fibroblast proliferation in vitro and ex vivo. Our studies demonstrate that the primary mode of action for Adaprev is potentially via a physical, non-chemical, hyperosmotic effect. PMID:25383548

  4. Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions.

    PubMed

    Yamamura, Satoshi; Abe, Masao; Nakagawa, Masanori; Ochi, Shinichiro; Ueno, Shu-ichi; Okada, Motohiro

    2011-03-01

    The atypical antidepressant, mirtazapine enhances noradrenergic transmission, but its effects on serotonergic transmission remain to be clarified. The present study determined the effects of acute and chronic administration of mirtazapine on serotonergic transmissions in raphe nuclei and their innervation regions, frontal and entorhinal cortex, using multiple-probes microdialysis with real-time PCR and western blotting. Acute administration of mirtazapine did not affect extracellular serotonin level in raphe nuclei or cortex; however, chronic administration increased extracellular serotonin level in raphe nuclei without affecting that in cortex. Blockade of 5-HT1A receptor, but not that of the 5-HT2A/2C receptor, enhanced the effects of acute administration of mirtazapine on extracellular serotonin level in raphe nuclei. Chronic mirtazapine administration reduced the inhibitory function associated with somatodendritic 5-HT1A receptor in raphe nuclei, but enhanced postsynaptic 5-HT1A receptor in serotonergic innervated cortical regions. Chronic administration reduced the expression of mRNA and protein of serotonin transporter and 5-HT1A receptor in raphe nuclei, but not in the cortices. These results suggested that acute administration of mirtazapine probably activated serotonergic transmission, but its stimulatory action was abolished by activated inhibitory 5-HT1A receptor. Chronic administration of mirtazapine resulted in increased extracellular serotonin level via reduction of serotonin transporter with reduction of somatodendritic 5-HT1A autoreceptor function in raphe nuclei. These pharmacological actions of mirtazapine include its serotonergic profiles as noradrenergic and specific serotonergic antidepressant (NaSSA). PMID:21195096

  5. 20 CFR 30.2 - In general, how have the tasks associated with the administration of EEOICPA claims process been...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... an administrative review process for claimants who disagree with its recommended and final adverse... cancer claims (see § 30.115). HHS also has exclusive control of the process for designating classes of... regulations governing that process at 42 CFR part 83. Finally, HHS has promulgated regulations at 42 CFR...

  6. 7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture. 356.4 Section 356.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  7. 26 CFR 301.7430-8 - Administrative costs incurred in damage actions for violations of section 362 or 524 of the...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... for violations of section 362 or 524 of the Bankruptcy Code. 301.7430-8 Section 301.7430-8 Internal... Administrative costs incurred in damage actions for violations of section 362 or 524 of the Bankruptcy Code. (a... Service relating to the willful violation of section 362 or 524 of the Bankruptcy Code only if...

  8. 76 FR 42713 - Notice of Meeting; Administration for Native Americans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    .... FOR FURTHER INFORMATION CONTACT: Lillian A. Sparks, Commissioner, Administration for Native Americans... for Native Americans, 370 L'Enfant Promenade, SW., Washington, DC 20447, anacommissioner@acf.hhs.gov... HUMAN SERVICES Administration for Children and Families Notice of Meeting; Administration for...

  9. Medicaid program; Medicaid managed care. Health Care Financing Administration (HCFA), HHS. Final rule with comment period.

    PubMed

    2001-01-19

    This final rule with comment period amends the Medicaid regulations to implement provisions of the Balanced Budget Act of 1997 (BBA) that allow the States greater flexibility by permitting them to amend their State plan to require certain categories of Medicaid beneficiaries to enroll in managed care entities without obtaining waivers if beneficiary choice is provided; establish new beneficiary protections in areas such as quality assurance, grievance rights, and coverage of emergency services; eliminate certain requirements viewed by State agencies as impediments to the growth of managed care programs, such as the enrollment composition requirement, the right to disenroll without cause at any time, and the prohibition against enrollee cost-sharing. In addition, this final rule expands on regulatory beneficiary protections provided to enrollees of prepaid health plans (PHPs) by requiring that PHPs comply with specified BBA requirements that would not otherwise apply to PHPs.

  10. Antinociceptive action of diphenyl diselenide in the nociception induced by neonatal administration of monosodium glutamate in rats.

    PubMed

    Rosa, Suzan G; Quines, Caroline B; da Rocha, Juliana T; Bortolatto, Cristiani F; Duarte, Thiago; Nogueira, Cristina W

    2015-07-01

    Monosodium glutamate (MSG) is a neuroexcitatory amino acid commonly used as flavoring of foods. MSG neonatal administration to animals leads to behavioral and physiological disorders in adulthood, including increased pain sensitivity. This study aimed to investigate the effect of diphenyl diselenide (PhSe)2, an organoselenium compound with pharmacological properties already documented, on nociception induced by MSG. Newborn Wistar rats received 10 subcutaneous injections of MSG at a dose of 4.0g/kg or saline (once daily). At the 60th day of life, the rats were daily treated with (PhSe)2 (1mg/kg) or vehicle (canola oil) by the intragastric route for 7 days. The behavioral tests (locomotor activity, hot plate, tail-immersion and mechanical allodynia) were carried out. Ex vivo assays were performed in samples of hippocampus to determine Na(+), K(+)-ATPase and Ca(2+)-ATPase activities, cytokine levels and [(3)H]glutamate uptake. The results demonstrated that MSG increased nociception in the hot plate test and in the mechanical allodynia stimulated by Von-Frey hair but did not alter the tail immersion test. (PhSe)2 reversed all nociceptive behaviors altered by MSG. MSG caused an increase in Na(+),K(+)-ATPase and Ca(2+)-ATPase activities and in pro-inflammatory cytokine levels and a decrease in the anti-inflammatory cytokine and in the [(3)H]glutamate uptake. (PhSe)2 was effective in reversing all alterations caused by MSG. The results indicate that (PhSe)2 had a potential antinociceptive and anti-inflammatory action in the MSG model.

  11. 10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... for Information Services and Administration and Chief Information Officer. (a) The Deputy Executive Director for Information Services and Administration and Chief Information Officer, on the basis of...

  12. Green Team Recognized with HHS Green Champion Award Honorable Mention | Poster

    Cancer.gov

    Courtesy of the NCI at Frederick Green Team The NCI at Frederick Green Team received a Department of Health and Human Services (HHS) Green Champion Award honorable mention in June for the team’s plant swap initiative, begun in October 2012.  “The Green Team has been doing a great job this past year, and it is wonderful that their efforts have been recognized by the HHS through the Green Champion Awards,” said Craig Reynolds, Ph.D., director of the NCI Office of Scientific Operations (OSO). 

  13. Unified agenda of federal regulatory and deregulatory actions--HHS. Semiannual regulatory agenda.

    PubMed

    1998-04-27

    The President's Executive Order 12866 and the Regulatory Flexibility Act of 1980 require the semiannual publication of an agenda which summarizes all current, projected, and recently completed rulemakings of the Department. The agenda enables the public to know about and to participate in the Department's regulations development work. The last such agenda was published on October 29, 1997.

  14. A Response to Recent Board of Regents' Action on Business Administration Education and a Critique of the Call for Business Administration Accreditation.

    ERIC Educational Resources Information Center

    Blanchard, Bryan

    In May 1986, the Board of Regents of Higher Education in Massachusetts accepted a report of a statewide program review in postsecondary business administration education. This critique of the program review report focuses specifically on the board-adopted requirement that public senior institutions seek accreditation from the American Assembly of…

  15. 42 CFR 59a.7 - Other HHS regulations that apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... include, but are not necessarily limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR parts 6 and 8—Inventions and patents 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant appeals procedures...

  16. 42 CFR 64.9 - Other HHS regulations that apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals procedures. 45 CFR part 76—subparts A-F. Governmentwide debarment and suspension...

  17. 42 CFR 64.9 - Other HHS regulations that apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals procedures. 45 CFR part 76—subparts A-F. Governmentwide debarment and suspension...

  18. 42 CFR 64.9 - Other HHS regulations that apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals procedures. 45 CFR part 76—subparts A-F. Governmentwide debarment and suspension...

  19. 42 CFR 64.9 - Other HHS regulations that apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals procedures. 45 CFR part 76—subparts A-F. Governmentwide debarment and suspension...

  20. 42 CFR 64.9 - Other HHS regulations that apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals procedures. 45 CFR part 76—subparts A-F. Governmentwide debarment and suspension...

  1. 42 CFR 59a.7 - Other HHS regulations that apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... include, but are not necessarily limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR parts 6 and 8—Inventions and patents 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant appeals procedures...

  2. 42 CFR 52d.8 - Other HHS regulations that apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... other regulations apply to grants under this subpart. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant...

  3. 42 CFR 52d.8 - Other HHS regulations that apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... other regulations apply to grants under this subpart. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant...

  4. 42 CFR 52d.8 - Other HHS regulations that apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... other regulations apply to grants under this subpart. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant...

  5. 42 CFR 52d.8 - Other HHS regulations that apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... other regulations apply to grants under this subpart. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant...

  6. 42 CFR 52d.8 - Other HHS regulations that apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... other regulations apply to grants under this subpart. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure 45 CFR part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45 CFR part 75—Informal grant...

  7. 48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Requirement for retention of FAC-C and HHS SAC certification. 301.603-74 Section 301.603-74 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career...

  8. 78 FR 66653 - Patient Protection and Affordable Care Act; HHS Notice of Benefit and Payment Parameters for 2014...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ...-04902 (78 FR 15410), the final rule entitled, ``Patient Protection and Affordable Care Act; HHS Notice... Affordable Care Act; HHS Notice of Benefit and Payment Parameters for 2014''. This correcting amendment... section reference to the Affordable Care Act. On page 15495, in our discussion of estimating the value...

  9. 2 CFR 376.995 - Principal (HHS supplement to government-wide definition at 2 CFR 180.995).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Definitions § 376.995 Principal (HHS supplement to government-wide definition at 2 CFR 180.995). Principal means individuals, in addition to those listed at 2 CFR 180.995, who participate in HHS covered... definition at 2 CFR 180.995). 376.995 Section 376.995 Grants and Agreements Federal Agency Regulations...

  10. 45 CFR 74.12 - Forms for applying for HHS financial assistance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... report clearance requirements of 5 CFR part 1320, “Controlling Paperwork Burdens on the Public,” with... pursuant to 5 CFR part 1320. (c) For Federal programs covered by E.O. 12372, as amended by E.O. 12416... also 45 CFR part 100.) (d) HHS awarding agencies that do not use the SF-424 form will indicate on...

  11. 42 CFR 73.5 - Exemptions for HHS select agents and toxins.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days...

  12. 42 CFR 73.5 - Exemptions for HHS select agents and toxins.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days...

  13. Five Years of HHS Home Health Care Evaluations: Using Evaluation to Change National Policy

    ERIC Educational Resources Information Center

    Brandon, Paul R.; Smith, Nick L.; Grob, George F.

    2012-01-01

    In 1997, American Evaluation Association member George Grob, now retired from the U.S. Department of Health and Human Services (HHS) and currently President of the Center for Public Program Evaluation, made a testimony on Medicare home health care fraud and abuse before the U.S. Senate Special Committee on Aging. The occasion was to announce the…

  14. 45 CFR 74.12 - Forms for applying for HHS financial assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... report clearance requirements of 5 CFR part 1320, “Controlling Paperwork Burdens on the Public,” with... pursuant to 5 CFR part 1320. (c) For Federal programs covered by E.O. 12372, as amended by E.O. 12416... also 45 CFR part 100.) (d) HHS awarding agencies that do not use the SF-424 form will indicate on...

  15. 42 CFR 51d.8 - Which other HHS regulations apply to these awards?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other...

  16. 42 CFR 51d.8 - Which other HHS regulations apply to these awards?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other...

  17. 42 CFR 51d.8 - Which other HHS regulations apply to these awards?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other...

  18. 42 CFR 51d.8 - Which other HHS regulations apply to these awards?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other...

  19. 42 CFR 51d.8 - Which other HHS regulations apply to these awards?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other...

  20. 75 FR 53971 - Guidance for Industry and Food and Drug Administration Staff; Impact-Resistant Lenses: Questions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-02

    ...; Impact-Resistant Lenses: Questions and Answers; Availability AGENCY: Food and Drug Administration, HHS... guidance entitled ``Impact-Resistant Lenses: Questions and Answers.'' This guidance document answers manufacturer, importer, and consumer questions on impact-resistant lenses, including questions on...

  1. 78 FR 23263 - Administration for Children and Families

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... HUMAN SERVICES Administration for Children and Families Submission for OMB Review; Comment Request Title... Administration for Children and Families (ACF), U.S. Department of Health and Human Services (HHS) is proposing a... local children and families, program and staff characteristics, and community characteristics);...

  2. Understanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities.

    PubMed

    Carey, Gemma; Friel, Sharon

    2015-10-11

    Many of the societal level factors that affect health - the 'social determinants of health (SDH)' - exist outside the health sector, across diverse portfolios of government, and other major institutions including non-governmental organisations (NGOs) and the private sector. This has created growing interest in how to create and implement public policies which will drive better and fairer health outcomes. While designing policies that can improve the SDH is critical, so too is ensuring they are appropriately administered and implemented. In this paper, we draw attention to an important area for future public health consideration - how policies are managed and implemented through complex administrative layers of 'the state.' Implementation gaps have long been a concern of public administration scholarship. To precipitate further work in this area, in this paper, we provide an overview of the scholarly field of public administration and highlight its role in helping to understand better the challenges and opportunities for implementing policies and programs to improve health equity.

  3. 77 FR 74183 - Farm Credit Administration Board Action To Approve a Plan of Voluntary Liquidation for, and To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... the Charter of, the Farm Credit Finance Corporation of Puerto Rico AGENCY: Farm Credit Administration... voluntary liquidation of the Farm Credit Finance Corporation of Puerto Rico (FCFCPR) without the appointment... Credit Finance Corporation of Puerto Rico under FCA's regulation Sec. 627.2795--Voluntary Liquidation...

  4. An Action-Oriented Perspective on Caring Leadership: A Qualitative Study of Higher Education Administrators' Positive Leadership Experiences

    ERIC Educational Resources Information Center

    Uusiautti, Satu

    2013-01-01

    Interest in human experiences, especially positive experiences, has been increasing ever since positive psychology gained a foothold in public attention. In this research, higher education administrators from Finland and the USA ("N"?=?13) were asked to describe positive or successful situations or chains of events in which their…

  5. Comparison of early reactions of the blood system in rats to immobilization, the action of hypoxia and the administration of erythopoietin

    NASA Technical Reports Server (NTRS)

    Gorizontov, P. D.; Fedotova, M. I.; Gudim, V. I.; Belousova, O. I.

    1980-01-01

    Three series of experiments were simultaneously carried on rats with the purpose of studying the action of different stimulants on the blood system; rats were subjected to immobilization, hypoxic hypoxia and erythropoietin administration. Changes in various cellular forms in the bone marrow, the thymus and the spleen were studied. A unitypical reaction, as in stress, was noted during the first hours; a reduction of the cell count in the lymphoid organs, a reduction of granulocytes and an increase of lymphoid cells in the bone marrow. The differences were chiefly quantitative. This was followed by stimulation of myelo and erythropoiesis determined by the specific features of the action applied. Nonspecific blood reaction was apparently due to activation of the adaptation mechanisms.

  6. NCI at Frederick Team Receives 2014 HHS Green Champions Award | Poster

    Cancer.gov

    A team of NCI and Leidos Biomedical Research employees at NCI at Frederick received the Energy and Fleet Management Award, one of the 2014 Department of Health and Human Services (HHS) Green Champions Awards, for comparing the costs and energy usage of two -80°C freezer technologies. This was the first scientific study to be jointly conducted by Leidos Biomedical Research’s Applied and Developmental Research Directorate (ADRD) and Facilities Maintenance and Engineering Directorate (FME).  

  7. 75 FR 73984 - Amendments to General Regulations of the Food and Drug Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ...'' (62 FR 62466, November 21, 1997). This guidance document may be accessed at http://www.fda.gov... HUMAN SERVICES Food and Drug Administration 21 CFR Parts 1, 14, and 17 RIN 0910-AG55 Amendments to General Regulations of the Food and Drug Administration AGENCY: Food and Drug Administration, HHS....

  8. Tracer kinetics and actions of oral and intraperitoneal 1,25-dihydroxyvitamin D3 administration in rats

    SciTech Connect

    Vieth, R.; Kooh, S.W.; Balfe, J.W.; Rawlins, M.; Tinmouth, W.W. )

    1990-11-01

    Tracer kinetic parameters of ({sup 3}H)-1,25(OH)2D3 were calculated from data obtained following its acute oral (p.o.) or intraperitoneal (i.p.) administration. In normal rats studied after the tracer had distributed into the body, the slope and intercept of the log-serum ({sup 3}H)-1,25(OH)2D3 versus time relationship were not significantly influenced by the route of administration. Pretreatment with 1,25(OH)2D3 (0.2 micrograms/100 g/day) by the same route as the tracer resulted in the following changes: in p.o. rats the serum ({sup 3}H)-1,25(OH)2D3 intercept was much lower but the slope was not changed; in i.p. rats the intercept was not changed but the slope was increased. Both p.o. and i.p. treatment with 1,25(OH)2D3 lowered the weight gain and diet consumption, and increased serum calcium, kidney tissue calcium and urinary excretion of orally administered {sup 45}Ca. All the measures of bioactivity were greater in the i.p. dosed rats than in the p.o. dosed rats. We conclude that the p.o. 1,25(OH)2D3 was less potent because of diminished bioavailability due to self induction of its presystemic metabolism and inactivation.

  9. 78 FR 41412 - Notice of Availability of Policy Document

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... HUMAN SERVICES Health Resources and Services Administration Notice of Availability of Policy Document AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Final Agency Guidance and... . Background: HHS' Health Resources and Services Administration (HRSA) provides grants to eligible...

  10. SAVEnergy Action Plan: National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northwest Fisheries Science Center, Seattle, Washington

    SciTech Connect

    Parker, S.A.; Wahlstrom, R.R.; Richman, E.E.; Sandusky, W.F. III; Dittmer, A.L.

    1995-05-01

    The Pacific Northwest Laboratory (PNL) conducted a SAVEnergy Audit of the National Oceanic and Atmospheric Administration`s (NOAA) National Marine Fisheries Service, Northwest Fisheries Science Center in Seattle, Washington. The objectives of this study were to evaluate the performance of all energy-consuming equipment in the facility, to estimate energy consumption and demand by end-use and to recommend energy conservation measures (ECMs) and water conservation measures (WCMs) to reduce costs . This section describes the facility and the systems encountered during the visit by the audit team. It also presents a summary of energy conservation measures. Section 2 shows energy consumption and costs for electricity, natural gas and water. A breakdown of energy consumed by end-use is also presented. Recommended energy conservation measures are presented in Section 3. Section 4 contains a discussion of operations and maintenance issues and other energy measures that can be implemented on a replace-on-failure basis rather than replacing immediately. Appendix A contains a three-year history of consumption, demand and cost for electric, natural gas and water utilities. Appendix B contains information on local weather data correlated to utility billing periods. A brief summary on Federal life-cycle costing is located in Appendix C along with the life-cycle cost analyses summaries for the energy and water conservation measures detailed in this report. Information on the rebate program sponsored by Seattle City Light, the electric utility, is located in Appendix D. Sample information for water-efficient equipment is located in Appendix E. Appendix F contains submittal forms to the Federal Energy Efficiency Fund for the energy conservation measures recommended in Section 3 of this report. A glossary of terms and abbreviations used in this report is located in Appendix G.

  11. 42 CFR 93.517 - The hearing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing... committed research misconduct and if the HHS administrative actions, including any debarment or suspension... research misconduct and the proposed HHS administrative actions. The ALJ does not review the...

  12. Health care programs: fraud and abuse; revisions to the civil money penalty provisions relating to the misuse of certain names, symbols and emblems--HHS. Final rule.

    PubMed

    1995-11-27

    In accordance with amendments to section 1140 of the Social Security Act, resulting from the Social Security Independence and Program Improvements Act of 1994, this final rule makes a number of revisions to the civil money penalty authority regulations relating to the misuse of certain symbols, emblems and names. Among other revisions, this rule eliminates the annual cap on penalties, includes the words and letters of the Department and Medicaid under the prohibition, and redefines a violation with regard to mailings. In addition, this final rule serves to remove references to Social Security and the Social Security Administration (SSA) from the HHS/OIG penalty regulations. The penalty regulations addressing the misuse of certain words, letters, symbols and emblems for SSA and its programs are being set forth in a new part of the Code of Federal Regulations published elsewhere in this edition of the Federal Register.

  13. Tobacco regulatory science: research to inform regulatory action at the Food and Drug Administration's Center for Tobacco Products.

    PubMed

    Ashley, David L; Backinger, Cathy L; van Bemmel, Dana M; Neveleff, Deborah J

    2014-08-01

    The U.S. Food and Drug Administration (FDA) promotes the development of regulatory science to ensure that a strong evidence base informs all of its regulatory activities related to the manufacture, marketing, and distribution of tobacco products as well as public education about tobacco product constituents and effects. Toward that end, the FDA's Center for Tobacco Products (CTP) provides funding for research studies with scientific aims that fall within its defined regulatory authority. However, given their traditional biomedical focus on basic and applied research, some researchers may not understand the principles of regulatory science or the types of studies CTP funds. The purpose of this paper is (1) to clarify the definition of regulatory science as a distinct scientific discipline, (2) to explore the role of tobacco regulatory science in order to help researchers understand the parameters and types of research that can be funded by CTP, and (3) to describe the types of research efforts that will inform the FDA's public health framework for tobacco product regulation. PMID:24638850

  14. Tobacco regulatory science: research to inform regulatory action at the Food and Drug Administration's Center for Tobacco Products.

    PubMed

    Ashley, David L; Backinger, Cathy L; van Bemmel, Dana M; Neveleff, Deborah J

    2014-08-01

    The U.S. Food and Drug Administration (FDA) promotes the development of regulatory science to ensure that a strong evidence base informs all of its regulatory activities related to the manufacture, marketing, and distribution of tobacco products as well as public education about tobacco product constituents and effects. Toward that end, the FDA's Center for Tobacco Products (CTP) provides funding for research studies with scientific aims that fall within its defined regulatory authority. However, given their traditional biomedical focus on basic and applied research, some researchers may not understand the principles of regulatory science or the types of studies CTP funds. The purpose of this paper is (1) to clarify the definition of regulatory science as a distinct scientific discipline, (2) to explore the role of tobacco regulatory science in order to help researchers understand the parameters and types of research that can be funded by CTP, and (3) to describe the types of research efforts that will inform the FDA's public health framework for tobacco product regulation.

  15. We Need Action on Social Determinants of Health - but Do We Want It, too? Comment on "Understanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities".

    PubMed

    de Leeuw, Evelyne

    2016-02-27

    Recently a number of calls have been made to mobilise the arsenal of political science insights to investigate - and point to improvements in - the social determinants of health (SDH), and health equity. Recently, in this journal, such a rallying appeal was made for the field of public administration. This commentary argues that, although scholarly potential should justifiably be redirected to resolve these critical issues for humanity, a key ingredient in taking action may have been neglected. This factor is 'community.' Community health has been a standard element of the public health and health promotion, even political, repertoire for decades now. But this commentary claims that communities are insufficiently charged, equipped or appreciated to play the role that scholarship attributes (or occasionally avoids to identify) to them. Community is too important to not fully engage and understand. Rhetorical tools and inquiries can support their quintessential role.

  16. 77 FR 20826 - Guidance for Industry and Food and Drug Administration Staff; Food and Drug Administration and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ..., 2010 (75 FR 22599), FDA announced the availability of the draft guidance. Comments on the draft... the Federal Food, Drug, and Cosmetic Act; Availability AGENCY: Food and Drug Administration, HHS... Procedures for Section 513(g) Requests for Information under the Federal Food, Drug, and Cosmetic Act.''...

  17. Mechanisms of corticosteroid action on lymphocyte subpopulations. III. Differential effects of dexamethasone administration on subpopulations of effector cells mediating cellular cytotoxicity in man

    PubMed Central

    Parrillo, J. E.; Fauci, A. S.

    1978-01-01

    The present study investigated the effect of dexamethasone (DEX) administration on different populations of mononuclear cells and neutrophils mediating antibody-dependent cellular cytotoxicity (ADCC) against different target cells. Mononuclear cells (lymphocytes and monocytes) and neutrophils were obtained from twenty-seven normal volunteers at 0, 4, 24 and 48 hr after oral administration of 21 mg of DEX. ADCC was determined utilizing the following targets: human red blood cells (HRBC), Chang liver cells (Ch) and human heart cells (HHC). The predominant mononuclear effector in HRBC killing was shown to be a monocyte and in Ch and HHC killing, a K cell. As previously shown, DEX produced a profound monocytopenia and lymphocytopenia at 4 hr with a return of lymphocyte counts to normal and monocyte counts to supra-normal at 24 hr. At the point of maximal monocytopenia, monocyte-mediated HRBC killing decreased from a geometric mean of 14 to 4 lytic units per 108 effector cells (P<0·05) and rebounded at 24 hr to a mean of 39 lytic units (P<0·02) with the rebound monocytosis. At the point of absolute lymphopenia (4 hr), there was a relative enrichment in the proportion of lymphocytes bearing an Fc receptor (K cells, P<0·01). Concomitant with this was an increase in ADCC against Ch and HHC from geometric means of 1121 to 7172 lytic units and 939 to 7354 lytic units (P<0·001) respectively. Thus, a major action of DEX administration on mononuclear ADCC was to differentially enrich or deplete different effector cells to and from the circulation, causing changes in cytotoxicity. Since the cytotoxicity paralleled the proportion of effector cells, the cells remaining in the circulation following DEX administration retained normal antibody-dependent cytotoxic capabilities. Neutrophil-mediated ADCC against HRBC significantly increased at 4 hr from a geometric mean of 3785 to 20142 lytic units (P<0·02) concomitant with the blood neutrophilia and remained elevated for 72 hr

  18. Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide.

    PubMed

    Konsman, J P; Veeneman, J; Combe, C; Poole, S; Luheshi, G N; Dantzer, R

    2008-12-01

    Although receptors for the pro-inflammatory cytokine interleukin-1 have long been known to be expressed in the brain, their role in fever and behavioural depression observed during the acute phase response (APR) to tissue infection remains unclear. This may in part be due to the fact that interleukin-1 in the brain is bioactive only several hours after peripheral administration of bacterial lipopolysaccharide (LPS). To study the role of cerebral interleukin-1 action in temperature and behavioural changes, and activation of brain structures during the APR, interleukin-1 receptor antagonist (IL-1ra; 100 microg) was infused into the lateral brain ventricle 4 h after intraperitoneal (i.p.) LPS injection (250 microg/kg) in rats. I.p. LPS administration induced interleukin-1beta (IL-1beta) production in systemic circulation as well as in brain circumventricular organs and the choroid plexus. Intracerebroventricular (i.c.v.) infusion of IL-1ra 4 h after i.p. LPS injection attenuated the reduction in social interaction, a cardinal sign of behavioural depression during sickness, and c-Fos expression in the amygdala and bed nucleus of the stria terminalis. However, LPS-induced fever, rises in plasma corticosterone, body weight loss and c-Fos expression in the hypothalamus and caudal brainstem were not altered by i.c.v. infusion of IL-1ra. These findings, together with our previous observations showing that i.c.v. infused IL-1ra diffuses throughout perivascular spaces, where macrophages express interleukin-1 receptors, can be interpreted to suggest that circulating or locally produced brain IL-1beta acts on these cells to bring about behavioural depression and activation of limbic structures during the APR after peripheral LPS administration.

  19. Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide.

    PubMed

    Konsman, J P; Veeneman, J; Combe, C; Poole, S; Luheshi, G N; Dantzer, R

    2008-12-01

    Although receptors for the pro-inflammatory cytokine interleukin-1 have long been known to be expressed in the brain, their role in fever and behavioural depression observed during the acute phase response (APR) to tissue infection remains unclear. This may in part be due to the fact that interleukin-1 in the brain is bioactive only several hours after peripheral administration of bacterial lipopolysaccharide (LPS). To study the role of cerebral interleukin-1 action in temperature and behavioural changes, and activation of brain structures during the APR, interleukin-1 receptor antagonist (IL-1ra; 100 microg) was infused into the lateral brain ventricle 4 h after intraperitoneal (i.p.) LPS injection (250 microg/kg) in rats. I.p. LPS administration induced interleukin-1beta (IL-1beta) production in systemic circulation as well as in brain circumventricular organs and the choroid plexus. Intracerebroventricular (i.c.v.) infusion of IL-1ra 4 h after i.p. LPS injection attenuated the reduction in social interaction, a cardinal sign of behavioural depression during sickness, and c-Fos expression in the amygdala and bed nucleus of the stria terminalis. However, LPS-induced fever, rises in plasma corticosterone, body weight loss and c-Fos expression in the hypothalamus and caudal brainstem were not altered by i.c.v. infusion of IL-1ra. These findings, together with our previous observations showing that i.c.v. infused IL-1ra diffuses throughout perivascular spaces, where macrophages express interleukin-1 receptors, can be interpreted to suggest that circulating or locally produced brain IL-1beta acts on these cells to bring about behavioural depression and activation of limbic structures during the APR after peripheral LPS administration. PMID:19087175

  20. 41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Education (ED) or the Department of Health and Human Services (HHS) notify nonprofit organizations that surplus real property and related personal property is available for educational and public health... May the Department of Education (ED) or the Department of Health and Human Services (HHS)...

  1. 41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Education (ED) or the Department of Health and Human Services (HHS) notify nonprofit organizations that surplus real property and related personal property is available for educational and public health... May the Department of Education (ED) or the Department of Health and Human Services (HHS)...

  2. Co-administration of memantine with epinephrine produces a marked peripheral action in intensifying and prolonging analgesia in response to local skin pinprick in rats.

    PubMed

    Chen, Yu-Wen; Tzeng, Jann-Inn; Pan, He-Jia; Hung, Ching-Hsia; Chen, Yu-Chung; Wang, Jhi-Joung

    2014-06-27

    The purpose of this study was to examine the effect of epinephrine as adjuvant for memantine or lidocaine as an infiltrative anesthetic. Using a rat model of cutaneous trunci muscle reflex (CTMR), we evaluated the effects of adding epinephrine to memantine or lidocaine on infiltrative cutaneous analgesia. Lidocaine, a known local anesthetic, was used as control. We found that epinephrine, memantine, and lidocaine produced a dose-dependent local anesthetic effect as infiltrative cutaneous analgesia. On a 50% effective dose (ED50) basis, the relative potencies were epinephrine [0.012 (0.006-0.020)μmol]>memantine [4.010 (3.311-4.988)μmol]>lidocaine [6.177 (5.333-7.218)μmol] (P<0.05 for each comparison). Mixtures of epinephrine (2.7nmol or 13.7nmol) with drugs (memantine or lidocaine) at ED50 or ED95, respectively, enhanced the potency and prolonged the duration of action on infiltrative cutaneous analgesia. Intraperitoneal injection of co-administration of drugs (memantine or lidocaine) at ED95 with epinephrine (13.7nmol) produced no cutaneous analgesia (data not shown). Epinephrine, memantine, and lidocaine were shown to have local anesthetic effects as infiltrative cutaneous analgesia. Epinephrine increased the duration and potency of memantine and lidocaine as an infiltrative anesthetic. PMID:24861513

  3. Co-administration of memantine with epinephrine produces a marked peripheral action in intensifying and prolonging analgesia in response to local skin pinprick in rats.

    PubMed

    Chen, Yu-Wen; Tzeng, Jann-Inn; Pan, He-Jia; Hung, Ching-Hsia; Chen, Yu-Chung; Wang, Jhi-Joung

    2014-06-27

    The purpose of this study was to examine the effect of epinephrine as adjuvant for memantine or lidocaine as an infiltrative anesthetic. Using a rat model of cutaneous trunci muscle reflex (CTMR), we evaluated the effects of adding epinephrine to memantine or lidocaine on infiltrative cutaneous analgesia. Lidocaine, a known local anesthetic, was used as control. We found that epinephrine, memantine, and lidocaine produced a dose-dependent local anesthetic effect as infiltrative cutaneous analgesia. On a 50% effective dose (ED50) basis, the relative potencies were epinephrine [0.012 (0.006-0.020)μmol]>memantine [4.010 (3.311-4.988)μmol]>lidocaine [6.177 (5.333-7.218)μmol] (P<0.05 for each comparison). Mixtures of epinephrine (2.7nmol or 13.7nmol) with drugs (memantine or lidocaine) at ED50 or ED95, respectively, enhanced the potency and prolonged the duration of action on infiltrative cutaneous analgesia. Intraperitoneal injection of co-administration of drugs (memantine or lidocaine) at ED95 with epinephrine (13.7nmol) produced no cutaneous analgesia (data not shown). Epinephrine, memantine, and lidocaine were shown to have local anesthetic effects as infiltrative cutaneous analgesia. Epinephrine increased the duration and potency of memantine and lidocaine as an infiltrative anesthetic.

  4. 42 CFR 1007.20 - Circumstances in which data mining is permissible and approval by HHS Office of Inspector General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Circumstances in which data mining is permissible... CONTROL UNITS § 1007.20 Circumstances in which data mining is permissible and approval by HHS Office of Inspector General. (a) Notwithstanding § 1007.19(e)(2), a MFCU may engage in data mining as defined in...

  5. 42 CFR 1007.20 - Circumstances in which data mining is permissible and approval by HHS Office of Inspector General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Circumstances in which data mining is permissible... CONTROL UNITS § 1007.20 Circumstances in which data mining is permissible and approval by HHS Office of Inspector General. (a) Notwithstanding § 1007.19(e)(2), a MFCU may engage in data mining as defined in...

  6. 42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions §...

  7. 42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions §...

  8. 42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions §...

  9. 42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions §...

  10. 45 CFR 1303.21 - Procedures for appeal by current or prospective delegate agencies to the responsible HHS official...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... supportive of this position, including all written material or documentation submitted to the grantee under... copy of the appeal and all material filed with the responsible HHS official must be simultaneously... alleged defects and deficiencies in the delegate agency's application or in the operation of its...

  11. 2 CFR 376.935 - Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...-wide definition at 2 CFR 180.935). 376.935 Section 376.935 Grants and Agreements Federal Agency... SUSPENSION Definitions § 376.935 Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935... transactions pursuant to the statutes listed in 2 CFR 180.935, and pursuant to Title XI of the Social...

  12. 2 CFR 376.995 - Principal (HHS supplement to government-wide definition at 2 CFR 180.995).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... definition at 2 CFR 180.995). 376.995 Section 376.995 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.995 Principal (HHS supplement to government-wide definition at 2 CFR 180.995)....

  13. 2 CFR 376.935 - Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...-wide definition at 2 CFR 180.935). 376.935 Section 376.935 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.935 Disqualified. (HHS supplement to government-wide definition at 2 CFR...

  14. 2 CFR 376.995 - Principal (HHS supplement to government-wide definition at 2 CFR 180.995).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... definition at 2 CFR 180.995). 376.995 Section 376.995 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.995 Principal (HHS supplement to government-wide definition at 2 CFR 180.995)....

  15. 2 CFR 376.995 - Principal (HHS supplement to government-wide definition at 2 CFR 180.995).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... definition at 2 CFR 180.995). 376.995 Section 376.995 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.995 Principal (HHS supplement to government-wide definition at 2 CFR 180.995)....

  16. 2 CFR 376.935 - Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...-wide definition at 2 CFR 180.935). 376.935 Section 376.935 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.935 Disqualified. (HHS supplement to government-wide definition at 2 CFR...

  17. 2 CFR 376.995 - Principal (HHS supplement to government-wide definition at 2 CFR 180.995).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... definition at 2 CFR 180.995). 376.995 Section 376.995 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.995 Principal (HHS supplement to government-wide definition at 2 CFR 180.995)....

  18. 2 CFR 376.935 - Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...-wide definition at 2 CFR 180.935). 376.935 Section 376.935 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.935 Disqualified. (HHS supplement to government-wide definition at 2 CFR...

  19. 2 CFR 376.935 - Disqualified. (HHS supplement to government-wide definition at 2 CFR 180.935).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...-wide definition at 2 CFR 180.935). 376.935 Section 376.935 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF HEALTH AND HUMAN SERVICES NONPROCUREMENT DEBARMENT AND SUSPENSION Definitions § 376.935 Disqualified. (HHS supplement to government-wide definition at 2 CFR...

  20. 78 FR 72321 - Patient Protection and Affordable Care Act; HHS Notice of Benefit and Payment Parameters for 2015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... c. Small group determination for risk adjustment d. Risk adjustment data validation e. HHS audits of... cost-sharing reduction amounts from reinsurance payments g. Audits h. Same covered life i. Reinsurance... of Benefit and Payment Parameters for 2014 final rule (78 FR 15410) (2014 Payment Notice)...

  1. 42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions §...

  2. Medicare program; revision to accrual basis of accounting policy. Health Care Financing Administration (HCFA), HHS. Final rule.

    PubMed

    1999-09-27

    Medicare policy provides that payroll taxes that a provider becomes obligated to remit to governmental agencies are included in allowable costs only in the cost reporting period in which payment (upon which the payroll taxes are based) is actually made to an employee. Therefore, for payroll accrued in 1 year but not paid until the next year, the associated payroll taxes are not an allowable cost until the next year. This final rule provides for an exception when payment would be made to the employee in the current year but for the fact the regularly scheduled payment date is after the end of the year. In that case, the rule requires allowance in the current year of accrued taxes on payroll that is accrued through the end of the year but not paid until the beginning of the next year, thus allowing accrued taxes on end-of-the year payroll in the same year that the accrual of the payroll itself is allowed. The effect of this rule is not on the allowability of cost but rather only on the timing of payment; that is, the cost of payroll taxes on end-of-the-year payroll is allowable in the current period rather than in the following period. PMID:11010708

  3. 77 FR 20825 - Guidance for Industry and Food and Drug Administration Staff; User Fees for 513(g) Requests for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... classification information.'' In the Federal Register of April 29, 2010 (75 FR 22601), FDA announced the...; User Fees for 513(g) Requests for Information; Availability AGENCY: Food and Drug Administration, HHS... guidance entitled ``Guidance for Industry and Food and Drug Administration Staff; User Fees for...

  4. 77 FR 48159 - Draft Guidance for Industry and Food and Drug Administration Staff; Refuse To Accept Policy for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... Staff; Refuse To Accept Policy for 510(k)s; Availability AGENCY: Food and Drug Administration, HHS... draft guidance entitled ``Refuse to Accept Policy for 510(k)s.'' The purpose of this document is to... (510(k)) submission is administratively complete, which determines whether it should be accepted...

  5. 59 FR- Administration on Children, Youth and Families; Youth Gang Drug Prevention Program; Availability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-07-12

    ... and Families published a program announcement in the Federal Register (59 FR 23867). The announcement...; Youth Gang Drug Prevention Program; Availability of Fiscal Year 1994 Funds and Request for Applications... (ACF); HHS. ACTION: Extension of closing date for submittal of applications under the Youth Gang...

  6. The HHS-HCC risk adjustment model for individual and small group markets under the Affordable Care Act.

    PubMed

    Kautter, John; Pope, Gregory C; Ingber, Melvin; Freeman, Sara; Patterson, Lindsey; Cohen, Michael; Keenan, Patricia

    2014-01-01

    Beginning in 2014, individuals and small businesses are able to purchase private health insurance through competitive Marketplaces. The Affordable Care Act (ACA) provides for a program of risk adjustment in the individual and small group markets in 2014 as Marketplaces are implemented and new market reforms take effect. The purpose of risk adjustment is to lessen or eliminate the influence of risk selection on the premiums that plans charge. The risk adjustment methodology includes the risk adjustment model and the risk transfer formula. This article is the second of three in this issue of the Review that describe the Department of Health and Human Services (HHS) risk adjustment methodology and focuses on the risk adjustment model. In our first companion article, we discuss the key issues and choices in developing the methodology. In this article, we present the risk adjustment model, which is named the HHS-Hierarchical Condition Categories (HHS-HCC) risk adjustment model. We first summarize the HHS-HCC diagnostic classification, which is the key element of the risk adjustment model. Then the data and methods, results, and evaluation of the risk adjustment model are presented. Fifteen separate models are developed. For each age group (adult, child, and infant), a model is developed for each cost sharing level (platinum, gold, silver, and bronze metal levels, as well as catastrophic plans). Evaluation of the risk adjustment models shows good predictive accuracy, both for individuals and for groups. Lastly, this article provides examples of how the model output is used to calculate risk scores, which are an input into the risk transfer formula. Our third companion paper describes the risk transfer formula.

  7. The HHS-HCC risk adjustment model for individual and small group markets under the Affordable Care Act.

    PubMed

    Kautter, John; Pope, Gregory C; Ingber, Melvin; Freeman, Sara; Patterson, Lindsey; Cohen, Michael; Keenan, Patricia

    2014-01-01

    Beginning in 2014, individuals and small businesses are able to purchase private health insurance through competitive Marketplaces. The Affordable Care Act (ACA) provides for a program of risk adjustment in the individual and small group markets in 2014 as Marketplaces are implemented and new market reforms take effect. The purpose of risk adjustment is to lessen or eliminate the influence of risk selection on the premiums that plans charge. The risk adjustment methodology includes the risk adjustment model and the risk transfer formula. This article is the second of three in this issue of the Review that describe the Department of Health and Human Services (HHS) risk adjustment methodology and focuses on the risk adjustment model. In our first companion article, we discuss the key issues and choices in developing the methodology. In this article, we present the risk adjustment model, which is named the HHS-Hierarchical Condition Categories (HHS-HCC) risk adjustment model. We first summarize the HHS-HCC diagnostic classification, which is the key element of the risk adjustment model. Then the data and methods, results, and evaluation of the risk adjustment model are presented. Fifteen separate models are developed. For each age group (adult, child, and infant), a model is developed for each cost sharing level (platinum, gold, silver, and bronze metal levels, as well as catastrophic plans). Evaluation of the risk adjustment models shows good predictive accuracy, both for individuals and for groups. Lastly, this article provides examples of how the model output is used to calculate risk scores, which are an input into the risk transfer formula. Our third companion paper describes the risk transfer formula. PMID:25360387

  8. The bare essentials. Release of LOM report leaves HHS to determine what should be covered by health benefits packages.

    PubMed

    Zigmond, Jessica

    2011-10-10

    In the wake of an IOM report on the criteria HHS should use to determine what benefits will be "essential" under reform, various stakeholders are weighing in. The National Association of Public Hospitals and Health Systems would like "enabling" services--such as language, transportation and case-management services--included, because they help make medical care more effective, says Xiaoyi Huang, left, of the NAPH. PMID:22111491

  9. 77 FR 31026 - Requirements for Importing Food and Drug Administration Regulated Products Into the United States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... to be discussed are FDA regulations with respect to importing pharmaceutical products, medical... meeting. SUMMARY: The Food and Drug Administration (FDA) is announcing the following meeting..., Chicago, IL 60661; 312-596-4217; email: lisa.misevicz@fda.hhs.gov . Registration: Send...

  10. 77 FR 22949 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... FR 3328) in which the Secretary of HHS (the Secretary) adopted the ICD-10-CM and ICD-10-PCS (ICD-10... Federal Register on August 22, 2008 (73 FR 49742); ``HIPAA Administrative Simplification: Modification to... Federal Register on August 22, 2008 (73 FR 49796) (hereinafter referred to as the ICD-10 proposed...

  11. A bill to prohibit the Administrator of the Federal Emergency Management Agency from taking administrative action to recover certain payments for disaster or emergency assistance, and for other purposes.

    THOMAS, 113th Congress

    Sen. Nelson, Bill [D-FL

    2016-09-28

    09/28/2016 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  12. Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA); interpretation of "federal public benefit"--HHS. Notice with comment period.

    PubMed

    1998-08-01

    This notice with comment period interprets the term "Federal public benefit" as used in Title IV of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA), Pub. L. 104-193, and identifies the HHS programs that provide such benefits under this interpretation. According to section 401 if PRWORA, aliens who are not "qualified aliens" are not eligible for any "Federal public benefit," unless the "Federal public benefit" falls within a specified exception. A "Federal public benefit" includes "any grant, contract, loan, professional license, or commercial license" provided to an individual, and also "any retirement, welfare, health, disability, public or assisted housing, postsecondary education, food assistance, unemployment benefit, or any other similar benefit for which payments or assistance are provided to an individual, household, or family eligibility unit." Under section 432, providers of a non-exempt "Federal public benefit" must verify that a person applying for the benefit is a qualified alien and is eligible to receive the benefit. The HHS programs that provide "Federal public benefits" and are not otherwise excluded from the definition by the exceptions provided in section 401(b) are: Adoption Assistance Administration on Developmental Disabilities (ADD)-State Developmental Disabilities Councils (direct services only) ADD-Special Projects (direct services only) ADD-University Affiliated Programs (clinical disability assessment services only) Adult Programs/Payments to Territories Agency for Health Care Policy and Research Dissertation Grants Child Care and Development Fund Clinical Training Grant for Faculty Development in Alcohol & Drug Abuse Foster Care Health Profession Education and Training Assistance Independent Living Program Job Opportunities for Low Income Individuals (JOLI) Low Income Home Energy Assistance Program (LIHEAP) Medicare Medicaid (except assistance for an emergency medical condition) Mental Health Clinical

  13. 78 FR 18420 - Special Permit Applications Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Pipeline and Hazardous Materials Safety Administration Special Permit Applications Actions AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of actions on special... processing of, special permits from the Department of Transportation's Hazardous Material Regulations (49...

  14. Office of the Assistant Secretary for Preparedness and Response; HHS Public Health Emergency Medical Countermeasures Enterprise implementation plan for chemical, biological, radiological and nuclear threats. Notice.

    PubMed

    2007-04-23

    The United States faces serious public health threats from the deliberate use of weapons of mass destruction (WMD)--chemical, biological, radiological, or nuclear (CBRN)--by hostile States or terrorists, and from naturally emerging infectious diseases that have a potential to cause illness on a scale that could adversely impact national security. Effective strategies to prevent, mitigate, and treat the consequences of CBRN threats is an integral component of our national security strategy. To that end, the United States must be able to rapidly develop, stockpile, and deploy effective medical countermeasures to protect the American people. The HHS Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) has taken a holistic, end-to-end approach that considers multiple aspects of the medical countermeasures mission including research, development, acquisition, storage, maintenance, deployment, and guidance for utilization. Phase one of this approach established the HHS PHEMCE Strategy for Chemical, Biological, Radiological, and Nuclear Threats (HHS PHEMCE Strategy). The HHS PHEMCE Strategy, published in the Federal Register on March 20, 2007, described a framework of strategic policy goals and objectives for identifying medical countermeasure requirements and establishing priorities for medical countermeasure evaluation, development and acquisition. These strategic policy goals and objectives were used to establish the Four Pillars upon which this HHS Public Health Emergency Medical Countermeasures Enterprise Implementation Plan (HHS PHEMCE Implementation Plan) is based. The HHS PHEMCE Implementation Plan considers the full spectrum of medical countermeasures-related activities, including research, development, acquisition, storage/maintenance, deployment, and utilization. The HHS PHEMCE Implementation Plan is consistent with the President's Biodefense for the 21st Century and is aligned with the National Strategy for Medical Countermeasures against

  15. 78 FR 12074 - Office of Biotechnology Activities; Recombinant DNA Research: Actions Under the NIH Guidelines...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... containing an HA from the Goose/Guangdong/1/96 lineage should become an HHS Select Agent (77 FR 63783... HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Recombinant DNA Research: Actions Under the NIH Guidelines for Research Involving Recombinant DNA Molecules (NIH...

  16. Actions Speak Louder than Words: A Case Study of the Perceptions of African American Women Administrators of Community at William Paterson University of New Jersey

    ERIC Educational Resources Information Center

    Howe-Barksdale, Sydney

    2007-01-01

    Globalization and privatization have begun to destabilize the patterns of university professional work and campus community. African American Women Administrators battle the unique challenges of racial and gender discrimination as well as the intersection of these issues. AAWAs face feelings of isolation and lack of trust, and struggles over power…

  17. A Reference-Intensive Embedded Librarian Program: Kresge Business Administration Library's Program to Support Action-Based Learning at the Ross School of Business

    ERIC Educational Resources Information Center

    Berdish, Laura; Seeman, Corey

    2010-01-01

    While a great deal of literature on embedded librarians in academic libraries is focused on the role of instructor, there are many other services that could be provided by librarians working closely with students. The Kresge Business Administration Library (Stephen M. Ross School of Business at the University of Michigan) has created a unique…

  18. 7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FORFEITURE... may waive any rights to any procedures relating to forfeiture under this subpart by signing a statement providing for waiver of such rights. (1) The Deputy Administrator shall publish a copy of...

  19. 75 FR 32952 - Draft Guidance for Industry and Food and Drug Administration Staff; “‘Harmful and Potentially...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... the Federal Food, Drug, and Cosmetic Act''; Availability AGENCY: Food and Drug Administration, HHS... Products as Used in Section 904(e) of the Federal Food, Drug, and Cosmetic Act.'' This draft guidance... Cosmetic Act.'' This draft guidance, when finalized, will discuss the meaning of the term ``harmful...

  20. The Department of Veterans Health Administration Office of Nursing Service, "transforming nursing in a national healthcare system: an example of transformation in action".

    PubMed

    Wertenberger, Sydney; Chapman, Kathleen M; Wright-Brown, Salena

    2011-01-01

    The Department of Veterans Health Administration Office of Nursing Service has embarked on a multiyear transformational process, an example of which is the development of an organization-wide nursing handbook. The development of this handbook offered the opportunity to improve collaboration, redefine expectations and behavior, as well as prepare for the future of Nursing within the Veterans Health Administration. The lessons learned from this process have revolved around the themes of leadership skills for managing high-level change often in a virtual environment; constant collaboration; that the practice of nursing will continue to evolve on the basis of new evidence, technology, customer expectations, and resources; and that the process to accomplish this goal is powerful.

  1. 40 CFR 265.224 - Response actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... action plan. The response action plan must set forth the actions to be taken if the action leakage rate... leakage rate for any sump, the owner or operator must: (1) Notify the Regional Administrator in writing of... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  2. 40 CFR 265.224 - Response actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... action plan. The response action plan must set forth the actions to be taken if the action leakage rate... leakage rate for any sump, the owner or operator must: (1) Notify the Regional Administrator in writing of... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  3. 78 FR 62417 - Import Administration; Change of Agency Name

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... International Trade Administration 19 CFR Parts 351, 354, and 356 RIN 0625-AA97 Import Administration; Change of Agency Name AGENCY: Import Administration, International Trade Administration, Commerce. ACTION: Final...), through internal department organizational orders, changed the name of ``Import Administration''...

  4. 75 FR 57820 - National Credit Union Administration Restoration Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... ADMINISTRATION National Credit Union Administration Restoration Plan AGENCY: National Credit Union Administration (NCUA). ACTION: Approval of National Credit Union Administration restoration plan. On September 16, 2010, the National Credit Union Administration (NCUA) implemented a Restoration Plan for the National...

  5. Effects of chronic vanadate administration in the STZ-induced diabetic rat. The antihyperglycemic action of vanadate is attributable entirely to its suppression of feeding.

    PubMed

    Malabu, U H; Dryden, S; McCarthy, H D; Kilpatrick, A; Williams, G

    1994-01-01

    Vanadate treatment can lower glycemia in diabetic rats. This action is generally attributed to vanadate's insulinomimetic properties, but vanadate also inhibits feeding, which could lower blood glucose. We therefore assessed the contribution of hypophagia to vanadate's antihyperglycemic action in a 3-week study of streptozocin-induced (STZ) diabetic rats. Untreated diabetic rats (n = 8) ate 54% more food than nondiabetic control rats (P < 0.001). Diabetic rats given sodium metavanadate (0.5 mg in 0.5 ml of water by gavage twice daily; n = 8) had significantly lower food intakes (P < 0.001) than untreated diabetic rats. In vanadate-treated diabetic rats, blood glucose levels were significantly lower than in untreated diabetic rats (P < 0.001). Untreated diabetic rats pair-fed to the food intake of the vanadate-treated diabetic rats (n = 8) showed virtually identical blood glucose falls (P > 0.05 vs. vanadate-treated diabetic rats). Vanadate treatment did not affect plasma insulin concentrations in diabetic rats. In nondiabetic rats (n = 8), vanadate treatment significantly reduced food intake (P < 0.05) and also lowered plasma insulin concentrations (P < 0.05) without significantly affecting glycemia. To investigate the mechanism of vanadate's hypophagic effect, we also measured regional hypothalamic levels of neuropeptide Y (NPY), a potent central appetite stimulant that is thought to drive hyperphagia in STZ-induced diabetes. Hypothalamic NPY concentrations rise markedly in diabetes and are normalized by insulin replacement. Unlike insulin, vanadate treatment did not normalize regional hypothalamic NPY concentrations in diabetic rats.(ABSTRACT TRUNCATED AT 250 WORDS)

  6. 78 FR 58314 - Advisory Committee for Pharmaceutical Science and Clinical Pharmacology; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... Pharmacology; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice... Science and Clinical Pharmacology. General Function of the Committee: To provide advice...

  7. 75 FR 10488 - Advisory Committee for Pharmaceutical Science and Clinical Pharmacology; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Pharmacology; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice... Science and Clinical Pharmacology. General Function of the Committee: To provide advice...

  8. 77 FR 42746 - Advisory Committee for Pharmaceutical Science and Clinical Pharmacology; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... Pharmacology; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice... Science and Clinical Pharmacology. General Function of the Committee: To provide advice...

  9. 78 FR 58315 - Advisory Committee for Pharmaceutical Science and Clinical Pharmacology; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... Pharmacology; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice... Science and Clinical Pharmacology. General Function of the Committee: To provide advice...

  10. 75 FR 11551 - Advisory Committee for Pharmaceutical Science and Clinical Pharmacology; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... Pharmacology; Notice of Meeting AGENCY: Food and Drug Administration, HHS. ACTION: Notice. This notice... Science and Clinical Pharmacology. General Function of the Committee: To provide advice...

  11. 42 CFR 93.509 - Computation of time.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions...

  12. 42 CFR 93.518 - Witnesses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions...

  13. Regulation of Hippocampal Cannabinoid CB1 Receptor Actions by Adenosine A1 Receptors and Chronic Caffeine Administration: Implications for the Effects of Δ9-Tetrahydrocannabinol on Spatial Memory

    PubMed Central

    Sousa, Vasco C; Assaife-Lopes, Natália; Ribeiro, Joaquim A; Pratt, Judith A; Brett, Ros R; Sebastião, Ana M

    2011-01-01

    The cannabinoid CB1 receptor-mediated modulation of γ-aminobutyric acid (GABA) release from inhibitory interneurons is important for the integrity of hippocampal-dependent spatial memory. Although adenosine A1 receptors have a central role in fine-tuning excitatory transmission in the hippocampus, A1 receptors localized in GABAergic cells do not directly influence GABA release. CB1 and A1 receptors are the main targets for the effects of two of the most heavily consumed psychoactive substances worldwide: Δ9-tetrahydrocannabinol (THC, a CB1 receptor agonist) and caffeine (an adenosine receptor antagonist). We first tested the hypothesis that an A1–CB1 interaction influences GABA and glutamate release in the hippocampus. We found that A1 receptor activation attenuated the CB1-mediated inhibition of GABA and glutamate release and this interaction was manifested at the level of G-protein activation. Using in vivo and in vitro approaches, we then investigated the functional implications of the adenosine–cannabinoid interplay that may arise following chronic caffeine consumption. Chronic administration of caffeine in mice (intraperitoneally, 3 mg/kg/day, for 15 days, >12 h before trials) led to an A1-mediated enhancement of the CB1-dependent acute disruptive effects of THC on a short-term spatial memory task, despite inducing a reduction in cortical and hippocampal CB1 receptor number and an attenuation of CB1 coupling with G protein. A1 receptor levels were increased following chronic caffeine administration. This study shows that A1 receptors exert a negative modulatory effect on CB1-mediated inhibition of GABA and glutamate release, and provides the first evidence of chronic caffeine-induced alterations on the cannabinoid system in the cortex and hippocampus, with functional implications in spatial memory. PMID:20927050

  14. 76 FR 5212 - Employment and Training Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Employment and Training Administration Comment Request for Information Collection for Internal Fraud and...: Employment and Training Administration (ETA), Department of Labor. ACTION: Notice. SUMMARY: The Department of.... Currently, the Employment and Training Administration is soliciting comments concerning the Office...

  15. 76 FR 45621 - Employment and Training Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... Employment and Training Administration Comment Request for Extension of Information Collection (Without... Temporary Employment Certification AGENCY: Employment and Training Administration. ACTION: Notice. SUMMARY... Training Administration (ETA) is soliciting comments concerning the extension of the approval for...

  16. 75 FR 6433 - Federal Aviation Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Federal Aviation Administration Notice of Availability of a Draft Environmental Assessment and Public...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Availability of a Draft Environmental... Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA) proposes to fund, construct,...

  17. 76 FR 78966 - Federal Aviation Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on the noise compatibility...

  18. 5 CFR 5501.102 - Designation of HHS components as separate agencies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Institutes of Health; (11) Program Support Center; and (12) Substance Abuse and Mental Health Services... agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES §...

  19. 5 CFR 5501.102 - Designation of HHS components as separate agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Institutes of Health; (11) Program Support Center; and (12) Substance Abuse and Mental Health Services... agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES §...

  20. 5 CFR 5501.102 - Designation of HHS components as separate agencies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Institutes of Health; (11) Program Support Center; and (12) Substance Abuse and Mental Health Services... agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES §...

  1. 5 CFR 5501.102 - Designation of HHS components as separate agencies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Institutes of Health; (11) Program Support Center; and (12) Substance Abuse and Mental Health Services... agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES §...

  2. 41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that...

  3. 41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify nonprofit organizations that surplus real property and related personal property is available for educational and public health purposes? 102-75.495 Section 102-75.495...

  4. 45 CFR Appendix B to Part 5b - Routine Uses Applicable to More Than One System of Records Maintained by HHS

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Records Maintained by HHS B Appendix B to Part 5b Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... or the Civil Rights Commission, issue a subpoena to the Department for records in this system of... agencies in defending claims against the United States when the claim is based upon an individual's...

  5. 45 CFR Appendix B to Part 5b - Routine Uses Applicable to More Than One System of Records Maintained by HHS

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Records Maintained by HHS B Appendix B to Part 5b Public Welfare Department of Health and Human Services... or the Civil Rights Commission, issue a subpoena to the Department for records in this system of... agencies in defending claims against the United States when the claim is based upon an individual's...

  6. 45 CFR Appendix B to Part 5b - Routine Uses Applicable to More Than One System of Records Maintained by HHS

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Records Maintained by HHS B Appendix B to Part 5b Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... or the Civil Rights Commission, issue a subpoena to the Department for records in this system of... agencies in defending claims against the United States when the claim is based upon an individual's...

  7. Reversing Cancer Multidrug Resistance in Xenograft Models via Orchestrating Multiple Actions of Functional Mesoporous Silica Nanoparticles.

    PubMed

    Yang, Debin; Wang, Tingfang; Su, Zhigui; Xue, Lingjing; Mo, Ran; Zhang, Can

    2016-08-31

    A multistimuli responsive drug delivery system (DDS) based on sulfhydryl and amino-cofunctionalized mesoporous silica nanoparticles (SH/NH2-MSNs) has been developed, in which the multifunctional hyaluronic acid (HA) derivatives were grafted onto the SH/NH2-MSNs by disulfide bonds for targeting delivery, controlling drug release and reversing multidrug resistance (MDR). The doxorubicin (Dox) loaded multifunctional HA derivatives modified mesoporous silica nanoparticles (Dox/HHS-MSNs) were enzyme and redox sensitive, which could respond to the intracellular stimuli of hyaluronidase (HAase) and glutathione (GSH) successively and prevent drug leakage before reaching the tumor tissues. The cellular uptake experiments showed that Dox/HHS-MSNs were vulnerable to be endocytosed into the Dox-resistant human breast adenocarcinoma (MCF-7/ADR) cells, efficiently realized the endolysosomal escape and remained in the cytoplasm. Because of orchestrating multiple actions above including active targeting, endolysosomal escape and efficient multilevel drug release, Dox/HHS-MSNs could induce the strongest apoptosis and cytotoxicity of MCF-7/ADR cells. Furthermore, a series of in vivo studies on MCF-7/ADR tumor-bearing xenograft mouse models demonstrated that Dox/HHS-MSNs possessed the enhanced tumor-targeting capacity and the best therapeutic efficacy to reverse cancer MDR. PMID:27420116

  8. 78 FR 28851 - Agency Information Collection Activities; Proposed Collection; Comment Request; Guidance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... Center for Veterinary Medicine Using the Food and Drug Administration's Electronic Submission Gateway AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities;...

  9. 76 FR 59139 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Submission for...: Food and Drug Administration, HHS. ] ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is... CONTACT: Juanmanuel Vilela, Office of Information Management, Food and Drug Administration, 1350...

  10. 76 FR 60501 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ...; Administrative Procedures, Policies, and Requirements AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Drug Marketing Act of 1987; Administrative Procedures, Policies, and Requirements--21 CFR Part 203... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Submission...

  11. 25 CFR 163.33 - Administrative appeals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Forest Management and Operations § 163.33 Administrative appeals. Any challenge to action under 25 CFR part 163... provisions of 25 CFR part 2, Appeals from administrative actions, except that an appeal of any action...

  12. 25 CFR 163.33 - Administrative appeals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Forest Management and Operations § 163.33 Administrative appeals. Any challenge to action under 25 CFR part 163... provisions of 25 CFR part 2, Appeals from administrative actions, except that an appeal of any action...

  13. 25 CFR 163.33 - Administrative appeals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Forest Management and Operations § 163.33 Administrative appeals. Any challenge to action under 25 CFR part 163... provisions of 25 CFR part 2, Appeals from administrative actions, except that an appeal of any action...

  14. 25 CFR 163.33 - Administrative appeals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Forest Management and Operations § 163.33 Administrative appeals. Any challenge to action under 25 CFR part 163... provisions of 25 CFR part 2, Appeals from administrative actions, except that an appeal of any action...

  15. 25 CFR 163.33 - Administrative appeals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Forest Management and Operations § 163.33 Administrative appeals. Any challenge to action under 25 CFR part 163... provisions of 25 CFR part 2, Appeals from administrative actions, except that an appeal of any action...

  16. 40 CFR 265.303 - Response actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  17. 40 CFR 264.223 - Response actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... action plan must set forth the actions to be taken if the action leakage rate has been exceeded. At a...) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the... action leakage rate has been exceeded, submit to the Regional Administrator the results of the...

  18. 40 CFR 265.259 - Response actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak determination system exceeds the action leakage rate for any... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  19. 40 CFR 265.303 - Response actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  20. 40 CFR 264.223 - Response actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... action plan must set forth the actions to be taken if the action leakage rate has been exceeded. At a...) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the... action leakage rate has been exceeded, submit to the Regional Administrator the results of the...

  1. 40 CFR 265.259 - Response actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak determination system exceeds the action leakage rate for any... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the...

  2. Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.

    PubMed

    Beppu, Hidehiko; Shimpo, Kan; Chihara, Takeshi; Kaneko, Takaaki; Tamai, Ikuko; Yamaji, Sachiyo; Ozaki, Sayaka; Kuzuya, Hiroshi; Sonoda, Shigeru

    2006-02-20

    We carried out three experimental trials to determine antidiabetic effects of Aloe arborescens Miller components. Firstly, ICR mice which received frequent injections of streptozotocin (Sz) in small doses (low-dose Sz-induced diabetes mice) were fed ad libitum with basal diets supplemented with components of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe) and Aloe vera Linne from 31 days before to 73 days after the Sz injections. Variation in blood glucose levels, incidence rates of insulitis and blood insulin levels were examined during the trial. As a result, groups receiving diets supplemented at the rate of 2% with whole leaf of Kidachi aloe and 10 KDa fraction powder (a fraction with less than 10 KDa molecular weight derived from Kidachi aloe leaf skin juice by ultra filtration) significantly suppressed the elevation of blood sugar as compared to a control group receiving basal diet. In contrast, there was no significant effect with Aloe vera leaf pulp powder. Insulitis emerged at the rate of 87% in the basal diet group. On the contrary, the whole aloe leaf and 10 KDa fraction groups significantly decreased the incidence of insulitis and incidence rates of whole aloe leaf and 10 KDa fraction powder were 51 and 38%, respectively. While insulin levels in the basal diet group averaged at 0.05 ng, more than four times the insulin level was observed in the 10 KDa group relative to the basal diet group. Secondary, the inhibitory effects of test materials on intestinal glucose absorption were observed using the jejunum of rats. A strong inhibitory action on intestinal glucose absorption was observed in the 10 KDa fraction powder group. Thirdly, phenol compounds derived from aloe in the blood serum and organs were quantitatively measured by a HPLC following forced administration of aloe components to rats to determine absorption kinetics of aloe components inside the body. The primary component of aloe phenol compounds is the same component of the 10 KDa

  3. Delayed Satiety-Like Actions and Altered Feeding Microstructure by a Selective Type 2 Corticotropin-Releasing Factor Agonist in Rats: Intra-Hypothalamic Urocortin 3 Administration Reduces Food Intake by Prolonging the Post-Meal Interval

    PubMed Central

    Fekete, Éva M; Inoue, Koki; Zhao, Yu; Rivier, Jean E; Vale, Wylie W; Szücs, Attila; Koob, George F; Zorrilla, Eric P

    2009-01-01

    Brain corticotropin-releasing factor/urocortin (CRF/Ucn) systems are hypothesized to control feeding, with central administration of ‘type 2’ urocortins producing delayed anorexia. The present study sought to identify the receptor subtype, brain site, and behavioral mode of action through which Ucn 3 reduces nocturnal food intake in rats. Non-food-deprived male Wistar rats (n = 176) were administered Ucn 3 into the lateral (LV) or fourth ventricle, or into the ventromedial or paraventricular nuclei of the hypothalamus (VMN, PVN) or the medial amygdala (MeA), regions in which Ucn 3 is expressed in proximity to CRF2 receptors. LV Ucn 3 suppressed ingestion during the third–fourth post-injection hours. LV Ucn 3 anorexia was reversed by cotreatment with astressin2-B, a selective CRF2 antagonist and not observed following equimole subcutaneous or fourth ventricle administration. Bilateral intra-VMN and intra-PVN infusion, more potently than LV infusion, reduced the quantity (57–73%) and duration of ingestion (32–68%) during the third–fourth post-infusion hours. LV, intra-PVN and intra-VMN infusion of Ucn 3 slowed the eating rate and reduced intake by prolonging the post-meal interval. Intra-VMN Ucn 3 reduced feeding bout size, and intra-PVN Ucn 3 reduced the regularity of eating from pellet to pellet. Ucn 3 effects were behaviorally specific, because minimal effective anorectic Ucn 3 doses did not alter drinking rate or promote a conditioned taste aversion, and site-specific, because intra-MeA Ucn 3 produced a nibbling pattern of more, but smaller meals without altering total intake. The results implicate the VMN and PVN of the hypothalamus as sites for Ucn 3-CRF2 control of food intake. PMID:17019404

  4. It barks, but will it bite? While HHS can review proposed insurance premium increases, it lacks the authority to actually stop them.

    PubMed

    Vesely, Rebecca

    2011-01-01

    HHS has new authority to review proposed insurance premium increases, but no real power to stop them. But at least some states without a rate review process say they welcome any support. "We are borderline at market failure," says Michael McRaith, left, director of the Illinois Department of Insurance. "The expectation is not that rates are going to dramatically or miraculously decline. But that rates will be more stable". PMID:21322334

  5. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the United... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that...

  6. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the United... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that...

  7. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the United... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that...

  8. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the United... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that...

  9. 42 CFR 93.516 - Standard and burden of proof.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... that are relevant to a decision to impose HHS administrative actions following a research misconduct... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.516 Standard and burden of proof. (a) Standard of proof. The standard...

  10. 46 CFR 327.34 - Court action.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Court action. 327.34 Section 327.34 Shipping MARITIME... AND LITIGATION Admiralty Extension Act Claims; Administrative Action and Litigation § 327.34 Court... under 46 U.S.C. 30101(a) against the Maritime Administration, shall institute a court action against...

  11. 46 CFR 327.34 - Court action.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Court action. 327.34 Section 327.34 Shipping MARITIME... AND LITIGATION Admiralty Extension Act Claims; Administrative Action and Litigation § 327.34 Court... under 46 U.S.C. 30101(a) against the Maritime Administration, shall institute a court action against...

  12. 45 CFR 77.4 - Remedial actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Remedial actions. 77.4 Section 77.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.4 Remedial actions. If, after the conclusion of the procedures set forth...

  13. Administrative Synergy

    ERIC Educational Resources Information Center

    Hewitt, Kimberly Kappler; Weckstein, Daniel K.

    2012-01-01

    One of the biggest obstacles to overcome in creating and sustaining an administrative professional learning community (PLC) is time. Administrators are constantly deluged by the tyranny of the urgent. It is a Herculean task to carve out time for PLCs, but it is imperative to do so. In this article, the authors describe how an administrative PLC…

  14. 76 FR 2745 - Federal Aviation Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Eighty-Fourth Meeting: RTCA Special Committee 159: Global Positioning System (GPS) AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special...

  15. 77 FR 64837 - Federal Aviation Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Federal Aviation Administration Fourth Meeting: RTCA Special Committee 227, Standards of Navigation Performance AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... 15, 2012. Kathy Hitt, Management Analyst, Business Operations Group, Federal Aviation...

  16. 5 CFR 532.413 - Simultaneous action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more...

  17. 5 CFR 532.413 - Simultaneous action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more...

  18. 5 CFR 532.413 - Simultaneous action.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more...

  19. 5 CFR 532.413 - Simultaneous action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more...

  20. 5 CFR 532.413 - Simultaneous action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more...

  1. Medicare and Medicaid programs; physicians' referrals to health care entities with which they have financial relationships. Health Care Financing Administration (HCFA), HHS. Final rule with comment period.

    PubMed

    2001-01-01

    This final rule with 90-day comment period (Phase I of this rulemaking) incorporates into regulations the provisions in paragraphs (a), (b), and (h) of section 1877 of the Social Security Act (the Act). Under section 1877, if a physician or a member of a physician's immediate family has a financial relationship with a health care entity, the physician may not make referrals to that entity for the furnishing of designated health services (DHS) under the Medicare program, unless an exception applies. The following services are DHS: clinical laboratory services; physical therapy services; occupational therapy services; radiology services, including magnetic resonance imaging, computerized axial tomography scans, and ultrasound services; radiation therapy services and supplies; durable medical equipment and supplies; parenteral and enteral nutrients, equipment, and supplies; prosthetics, orthotics, and prosthetic devices and supplies; home health services; outpatient prescription drugs; and inpatient and outpatient hospital services. In addition, section 1877 of the Act provides that an entity may not present or cause to be presented a Medicare claim or bill to any individual, third party payer, or other entity for DHS furnished under a prohibited referral, nor may we make payment for a designated health service furnished under a prohibited referral. Paragraph (a) of section 1877 of the Act includes the general prohibition. Paragraph (b) of the Act includes exceptions that pertain to both ownership and compensation relationships, including an in-office ancillary services exception. Paragraph (h) includes definitions that are used throughout section 1877 of the Act, including the group practice definition and the definitions for each of the DHS. We intend to publish a second final rule with comment period (Phase II of this rulemaking) shortly addressing, to the extent necessary, the remaining sections of the Act. Phase II of this rulemaking will address comments concerning the ownership and investment exceptions in paragraphs (c) and (d) and the compensation exceptions in paragraph (e) of section 1877 of the Act. Phase II of this rulemaking will also address comments concerning the reporting requirements and sanctions provided by paragraphs (f) and (g) of the Act, respectively, and include further consideration of the general exception to the referral prohibition related to both ownership/investment and compensation for services furnished in an ambulatory surgical center (ASC), end-stage renal dialysis facility, or by a hospice in section 411.355(d) of the regulations (this exception presently is in force and effect as to clinical laboratory services). In addition, Phase II of this rulemaking will address section 1903(s) of the Act, which extends aspects of the referral prohibition to the Medicaid Program. Phase II will also address comments received in response to this rulemaking, as appropriate, and certain proposals for new exceptions to section 1877 of the Act not included in the 1998 proposed rulemaking, but suggested in the public comments.

  2. National Practitioner Data Bank for Adverse Information on Physicians and other Health Care Practitioners: charge for self-queries. Health Resources and Services Administration, HHS. Final rule.

    PubMed

    1999-03-01

    This final rule amends the existing regulations implementing the Health Care Quality Improvement Act of 1986 (the Act), which established the National Practitioner Data Bank for Adverse Information on Physicians and Other Health Care Practitioners (the Data Bank). The final rule amends the existing fee structure so that the Data Bank can fully recover its costs, as required by law. This rule removes the prohibition against charging for self-queries and, therefore, allows the Data Bank to assess costs in an equitable manner. This is consistent with both the Freedom of Information Act and the Privacy Act which allow the Government to charge fees for the reproduction of records. The Data Bank will continue its current practice of sending to the practitioner in whose name it was submitted--automatically, without a request, and free of charge--a copy of every report received by the Data Bank for purposes of verification and dispute resolution.

  3. Medicare program; revision to accrual basis of accounting policy. Department of Health and Human Services (HHS), Health Care Financing Administration (HCFA). Final rule.

    PubMed

    1999-09-27

    Medicare policy provides that payroll taxes that a provider becomes obligated to remit to governmental agencies are included in allowable costs only in the cost reporting period in which payment (upon which the payroll taxes are based) is actually made to an employee. Therefore, for payroll accrued in 1 year but not paid until the next year, the associated payroll taxes are not an allowable cost until the next year. This final rule provides for an exception when payment would be made to the employee in the current year but for the fact that regularly scheduled payment date is after the end of the year. In that case, the rule requires allowance in the current year of accrued taxes on payroll that is accrued through the end of the year but not paid until the beginning of the next year, thus allowing accrued taxes on end-of-the year payroll in the same year that the accrual of the payroll itself is allowed. The effect of this rule is not on the allowability of cost but rather only on the timing of payment; that is, the cost of payroll taxes on end-of-the-year payroll is allowable in the current period rather than in the following period. PMID:10915462

  4. 78 FR 63989 - Request for Notification From Industry Organizations Interested in Participating in the Selection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Request for Notification From Industry Organizations... AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration...

  5. 78 FR 48689 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Announcement of...: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA)...

  6. 75 FR 77878 - Determination of Regulatory Review Period for Purposes of Patent Extension; FREESTYLE NAVIGATOR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ... HUMAN SERVICES Food and Drug Administration Determination of Regulatory Review Period for Purposes of Patent Extension; FREESTYLE NAVIGATOR AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) has determined the regulatory review period for...

  7. 75 FR 4077 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Submission for... Cattle AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... and Drug Administration, 5600 Fishers Lane, Rockville, MD 20857, 301-796-3793....

  8. 76 FR 11788 - Agency Information Collection Activities; Proposed Collection; Comment Request; Infant Formula...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed Collection; Comment Request; Infant Formula Label Statements Experimental Study AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an...

  9. 76 FR 72952 - Guidance for Industry on Nonclinical Evaluation of Late Radiation Toxicity of Therapeutic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Nonclinical Evaluation of Late Radiation Toxicity of Therapeutic Radiopharmaceuticals; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability...

  10. 78 FR 46347 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Announcement of Office of Management and Budget Approval; Environmental Impact Considerations AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing that...

  11. 76 FR 12743 - Medical Device Reporting; Malfunction Reporting Frequency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... HUMAN SERVICES Food and Drug Administration Medical Device Reporting; Malfunction Reporting Frequency AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA... continue to submit malfunction reports in full compliance with FDA's Medical Device Reporting...

  12. 77 FR 37413 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Coronary Heart Disease Health Claim AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing that a collection of information entitled ``Record... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Announcement...

  13. 77 FR 26284 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Submission for... of Harmful and Potentially Harmful Tobacco Constituents AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing that a proposed...

  14. 78 FR 16685 - Impax Laboratories, Inc.; Withdrawal of Approval of Bupropion Hydrochloride Extended-Release...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... HUMAN SERVICES Food and Drug Administration Impax Laboratories, Inc.; Withdrawal of Approval of Bupropion Hydrochloride Extended-Release Tablets, 300 Milligrams AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is withdrawing approval of...

  15. 77 FR 23267 - Agency Information Collection Activities; Proposed Collection; Comment Request; Guidance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... Medical Device User Fee Small Business Qualification and Certification AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an...

  16. 77 FR 26281 - Agency Information Collection Activities; Proposed Collection; Comment Request; Registration and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... Product Establishments and Listing of Ingredients in Tobacco Products AGENCY: Food and Drug Administration, HHS. ] ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an...

  17. 78 FR 46965 - Draft Guidance for Industry on Bioequivalence Recommendations for Mesalamine Rectal Suppositories...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Bioequivalence Recommendations for Mesalamine Rectal Suppositories; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a...

  18. 78 FR 73200 - Draft Guidance for Industry on Bioequivalence Recommendations for Paliperidone Palmitate Extended...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Bioequivalence Recommendations for Paliperidone Palmitate Extended-Release Injectable Suspension; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is...

  19. 77 FR 35688 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... HUMAN SERVICES Food and Drug Administration Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability...

  20. 78 FR 52777 - Draft Guidance for Industry on Bioequivalence Recommendations for Risperidone Injection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-26

    ... HUMAN SERVICES Food and Drug Administration (Formerly Docket No. 2007D-0168) Draft Guidance for Industry on Bioequivalence Recommendations for Risperidone Injection; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing...