Science.gov

Sample records for administration key results

  1. Key Obama officials leave administration

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2013-01-01

    Secretary of the Interior Ken Salazar is one of the latest members of the Obama administration to announce that he is leaving his position near the start of President Obama's second term in office. Salazar, who has served as interior secretary since January 2009, intends to leave the department by the end of March, the department noted on 16 January. Salazar joins a number of other key officials who are planning to leave the administration. They include Environmental Protection Agency administrator Lisa Jackson, National Oceanic and Atmospheric Administration administrator Jane Lubchenco, and U.S. Geological Survey director Marcia McNutt.

  2. Creating a Welcoming Environment: 4 Key Tips for Administrators

    ERIC Educational Resources Information Center

    Region IX Equity Assistance Center at WestEd, 2015

    2015-01-01

    Family-school partnerships boost student achievement and school improvement from preschool through high school. With family engagement as a priority and requirement for Local Control Accountability Plans (LCAPs), family engagement in schools matters more than ever. Four key tips for administrators for creating a welcoming environment are shared…

  3. New Security Results on Encrypted Key Exchange

    SciTech Connect

    Bresson, Emmanuel; Chevassut, Olivier; Pointcheval, David

    2003-12-15

    Schemes for encrypted key exchange are designed to provide two entities communicating over a public network, and sharing a (short) password only, with a session key to be used to achieve data integrity and/or message confidentiality. An example of a very efficient and ''elegant'' scheme for encrypted key exchange considered for standardization by the IEEE P1363 Standard working group is AuthA. This scheme was conjectured secure when the symmetric-encryption primitive is instantiated via either a cipher that closely behaves like an ''ideal cipher,'' or a mask generation function that is the product of the message with a hash of the password. While the security of this scheme in the former case has been recently proven, the latter case was still an open problem. For the first time we prove in this paper that this scheme is secure under the assumptions that the hash function closely behaves like a random oracle and that the computational Diffie-Hellman problem is difficult. Furthermore, since Denial-of-Service (DoS) attacks have become a common threat we enhance AuthA with a mechanism to protect against them.

  4. Key results from SB8 simulant flowsheet studies

    SciTech Connect

    Koopman, D. C.

    2013-04-26

    Key technically reviewed results are presented here in support of the Defense Waste Processing Facility (DWPF) acceptance of Sludge Batch 8 (SB8). This report summarizes results from simulant flowsheet studies of the DWPF Chemical Process Cell (CPC). Results include: Hydrogen generation rate for the Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles of the CPC on a 6,000 gallon basis; Volume percent of nitrous oxide, N2O, produced during the SRAT cycle; Ammonium ion concentrations recovered from the SRAT and SME off-gas; and, Dried weight percent solids (insoluble, soluble, and total) measurements and density.

  5. Key Questions on the Obama Administration's 2014 Education Budget Request. Issue Brief

    ERIC Educational Resources Information Center

    New America Foundation, 2013

    2013-01-01

    President Obama sent his fiscal year 2014 budget request to Congress on April 10, 2013. The New America Foundation's Education Policy Program released this subsequent issue brief, "Key Questions on the Obama Administration's 2014 Budget Request." Obama's budget request totals $71.2 billion in appropriations funding for the U.S. Department of…

  6. Librarians Look at Bibliography: Title and Key Word Index to Small Business Administration Bibliography Series

    ERIC Educational Resources Information Center

    Potter, Robert Ellis

    1972-01-01

    Since the U.S. Small Business Administration bibliography series'' is without an index and/or table-of-contents, this librarian has compiled a complete-title and key words index to this collection for all types of business and industrial libraries. (Author/NH)

  7. Lessons and key results from 30 years of imaging spectroscopy

    NASA Astrophysics Data System (ADS)

    Green, Robert O.

    2014-09-01

    Spectroscopy was first used in 1814 by Joseph von Fraunhofer as a scientific method for discovery, and to develop and test scientific hypotheses. From this beginning, spectroscopy evolved to a broadly used analytical tool for both science and applications. In the 1970's, technology began to enable a class of instruments that measure spectra for every point in an image. The first airborne imaging spectrometer developed at the Jet Propulsion Laboratory flew in 1982. Subsequently, a wide range of imaging spectrometers have been developed, many at the Jet Propulsion Laboratory, for airborne and space platforms and they have participated in NASA mission throughout the solar system. A key lesson over this time period has been the broad applicability of imaging spectrometers to pursue a range of science and application objectives wherever there is relevant signal in the spectral range from the ultra violet to the thermal infrared. As with all optical imaging instruments, imaging spectrometers have spectral, radiometric and spatial characteristics and related requirements. Of these, uniformity, radiometric precision, and calibration have been identified as critically important for the science and application utility of imaging spectrometer instruments. These key requirements are enabling for the most advanced imaging spectrometer algorithms that retrieve parameters with units and quantifiable uncertainties. The current trend in imaging spectrometer instrumentation is for broader spectral coverage and wider swath while improving uniformity, precision, and calibration. A companion emphasis is for lower mass, power and volume, with instruments taking advantage of the latest detector, optical, electronics and computational technologies. The number of imaging spectrometers in use is increasing every year and this trend is on track to continue.

  8. Key uncertainties in climate change policy: Results from ICAM-2

    SciTech Connect

    Dowlatabadi, H.; Kandlikar, M.

    1995-12-31

    A critical aspect of climate change decision-making is uncertainties in current understanding of the socioeconomic, climatic and biogeochemical processes involved. Decision-making processes are much better informed if these uncertainties are characterized and their implications understood. Quantitative analysis of these uncertainties serve to: inform decision makers about the likely outcome of policy initiatives; and help set priorities for research so that outcome ambiguities faced by the decision-makers are reduced. A family of integrated assessment models of climate change have been developed at Carnegie Mellon. These models are distinguished from other integrated assessment efforts in that they were designed from the outset to characterize and propagate parameter, model, value, and decision-rule uncertainties. The most recent of these models is ICAM 2.0. This model includes demographics, economic activities, emissions, atmospheric chemistry, climate change, sea level rise and other impact modules and the numerous associated feedbacks. The model has over 700 objects of which over 1/3 are uncertain. These have been grouped into seven different classes of uncertain items. The impact of uncertainties in each of these items can be considered individually or in combinations with the others. In this paper we demonstrate the relative contribution of various sources of uncertainty to different outcomes in the model. The analysis shows that climatic uncertainties are most important, followed by uncertainties in damage calculations, economic uncertainties and direct aerosol forcing uncertainties. Extreme uncertainties in indirect aerosol forcing and behavioral response to climate change (adaptation) were characterized by using bounding analyses; the results suggest that these extreme uncertainties can dominate the choice of policy outcomes.

  9. Human resource leadership: the key to improved results in health.

    PubMed

    O'Neil, Mary L

    2008-06-20

    This article is the lead article in the Human Resources for Health journal's first quarterly feature. The series of seven articles has been contributed by Management Sciences for Health (MSH) under the theme of leadership and management in public health and will be published article by article over the next few weeks. The journal has invited Dr Manuel M. Dayrit, Director of the WHO Department of Human Resources for Health and former Minister of Health for the Philippines to launch the feature with an opening editorial to be found in the journal's blog. This opening article describes the human resource challenges that managers around the world report and analyses why solutions often fail to be implemented. Despite rising attention to the acute shortage of health care workers, solutions to the human resource (HR) crisis are difficult to achieve, especially in the poorest countries. Although we are aware of the issues and have developed HR strategies, the problem is that some old systems of leading and managing human resources for health do not work in today's context. The Leadership Development Program (LDP) is grounded on the belief that good leadership and management can be learned and practiced at all levels. The case studies in this issue were chosen to illustrate results from using the LDP at different levels of the health sector. The LDP makes a profound difference in health managers' attitudes towards their work. Rather than feeling defeated by a workplace climate that lacks motivation, hope, and commitment to change, people report that they are mobilized to take action to change the status quo. The lesson is that without this capacity at all levels, global policy and national HR strategies will fail to make a difference.

  10. Nursing Faculty Shortage Nurses' Perceptions as a Key to Administrative Solutions

    ERIC Educational Resources Information Center

    Klocke, Evelyn M.

    2009-01-01

    The nursing faculty shortage is well documented. Higher education administrators turn away qualified student applicants because of the lack of qualified nursing faculty. Furthermore, they find recruitment and retention of qualified nursing faculty a challenge. The purpose of this study was to explore perceptions of the nursing faculty role, causes…

  11. 75 FR 33243 - Carbazole Violet Pigment 23 From India: Final Results of Countervailing Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... India: Preliminary Results of Countervailing Duty Administrative Review, 75 FR 977 (January 7, 2010... Administrative Review, 75 FR 26716 (May 12, 2010). Scope of the Order The merchandise covered by this order is... International Trade Administration Carbazole Violet Pigment 23 From India: Final Results of Countervailing...

  12. Key Performance Indicators: From Promise to Payoff. The Productivity for Results Series No. 2

    ERIC Educational Resources Information Center

    Casserly, Michael; Eugene, Michael

    2014-01-01

    This paper draws upon the expertise of two leading educators, Michael Casserly, director of the Council of the Great City Schools, and Michael Eugene, chief operating officer of the Orange County Public Schools in Florida. They outline a set of key performance indicators that some urban districts use to benchmark the results of their operating…

  13. Monitoring the Future: National Results on Adolescent Drug Use. Overview of Key Findings, 2006

    ERIC Educational Resources Information Center

    Johnston, Lloyd D., O'Malley, Patrick M.; Bachman, Jerald G.; Schulenberg, John E.

    2007-01-01

    This report provides a summary of drug use trends from a survey of nearly 50,000 eighth-, tenth-, and twelfth- grade students nationwide. It also includes perceived risk, personal disapproval, and perceived availability of each drug by this group. A synopsis of the methods used in the study and an overview of the key results from the 2006 survey…

  14. 75 FR 66347 - Brass Sheet and Strip From Germany: Amended Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ...., international freight) from the gross sales value. The Department clarified its ``automatic assessment... International Trade Administration Brass Sheet and Strip From Germany: Amended Final Results of Antidumping Duty Administrative Review AGENCY: Import Administration, International Trade Administration, U.S. Department...

  15. 78 FR 23220 - Lightweight Thermal Paper From Germany: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... Duty Orders: Lightweight Thermal Paper from Germany and the People's Republic of China, 73 FR 70959...; Preliminary Results Antidumping Duty Administrative Review; 2010-2011, 77 FR 73615 (December 11, 2012... International Trade Administration Lightweight Thermal Paper From Germany: Final Results of Antidumping...

  16. 65 FR 68978 - Electrolytic Manganese Dioxide From Greece: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-11-15

    ... Administrative Review: Electrolytic Manganese Dioxide from Greece, 65 FR 26570 (May 8, 2000) (Preliminary Results... INTERNATIONAL TRADE ADMINISTRATION (A-484-801) Electrolytic Manganese Dioxide From Greece: Final Results of... the antidumping duty order on electrolytic manganese dioxide from Greece. The review covers...

  17. 77 FR 73979 - Magnesium Metal From the Russian Federation: Notice of Reinstated Final Results of Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... Russian Federation: Final Results of Antidumping Duty Administrative Review, 73 FR 52642 (September 10... period April 1, 2006, through March 31, 2007. See Final Results, 73 FR at 52643. The CIT remanded the... Administrative Review Pursuant to Court Decision, 76 FR 13355 (March 11, 2011). On July 27, 2012, the...

  18. 77 FR 69792 - Certain Pasta From Turkey: Final Results of Countervailing Duty Administrative Review; 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... Notice of Countervailing Duty Order: Certain Pasta from Turkey, 61 FR 38546 (July 24, 1996), remains...: Preliminary Results of Countervailing Duty Administrative Review, 77 FR 46386 (August 3, 2012) (``Preliminary... Preliminary Results of the Countervailing Duty Administrative Review, 77 FR 11065 (February 24, 2012)....

  19. 75 FR 54090 - Stainless Steel Bar From India: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ...: Preliminary Results of Antidumping Duty Administrative Review 75 FR 12199 (March 15, 2010) (``Preliminary... Limit for the Final Results of the 2008-2009 Antidumping Duty Administrative Review, 75 FR 41438 (July...'') in room 1117 in the main Department building. See also Notice of Scope Rulings, 70 FR...

  20. Key Informants' Perspectives on Accredited Breast Cancer Centres: Results of a Survey.

    PubMed

    Kowalski, C; Wesselmann, S; Ansmann, L; Kreienberg, R; Pfaff, H

    2012-03-01

    This paper presents the results of a survey among key informants that was conducted between June and September 2011 in Breast Cancer Centers that were accredited according to the criteria of the German Cancer Society (DKG). The survey intended to assess the degree to which the breast cancer center concept was accepted among the key informants as well as to gain an overview over structures and processes in the centers. The Questionnaire for Breast Cancer Centres Key Informants 2011 (FRIZ 2011) was used with two reminders having been sent out. Questionnaires were sent back from 149 of the 243 initially contacted hospitals (response rate: 61.3 %). The vast majority of respondents indicated to be part of the Breast Cancer Center management. 110 of the 149 hospitals did also participate in the patient survey conducted in 2010. Among the key informants surveyed, the concept is highly accepted with regard to improvements in patient care. Overall, the concept is regarded as "good" or "very good" by almost all respondents. Both contact to resident doctors and the hospitals' reputations improved since the implementation of the concept. Quality and patient safety were more often on the agenda than financial performance in the quality circles with the main co-operation partners of the Breast Cancer Centers. PMID:25308982

  1. 75 FR 6352 - Certain Pasta from Italy: Notice of Final Results of the Twelfth Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... from Italy: Notice of Preliminary Results of Twelfth Antidumping Duty Administrative Review, 74 FR... Circumstances Review and Revocation, in Part, 74 FR 41120 (August 14, 2009). The merchandise subject to this... Eleventh Administrative Review and Partial Rescission of Review, 73 FR 75400 (December 11, 2008)....

  2. 76 FR 57955 - Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... Antidumping Duty Orders: Certain Polyester Staple Fiber From the Republic of Korea and Taiwan, 65 FR 33807... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty... administrative review of the antidumping duty order on certain polyester staple fiber from Taiwan. The period...

  3. 77 FR 54561 - Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... the order may be coated, usually with a silicon or other finish, or not coated. Polyester staple fiber... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty... administrative review of the antidumping duty order on certain polyester staple fiber from Taiwan. The period...

  4. 77 FR 46377 - Certain Pasta From Italy: Notice of Preliminary Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... Results of Antidumping Duty Administrative Review, 75 FR 6627 (February 10, 2010) (``SSSS from Mexico... Order and Amended Final Determination of Sales at Less Than Fair Value: Certain Pasta From Italy, 61 FR... Investigation; Opportunity To Request Administrative Review, 76 FR 38609 (July 1, 2011). \\3\\ The...

  5. 77 FR 39467 - Stainless Steel Bar From India: Final Results of the Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ...: Stainless Steel Bar from India, 59 FR 66915 (December 28, 1994). These cash deposit requirements, when... Rescission of the Antidumping Duty Administrative Review, 77 FR 13270 (March 6, 2012) (Preliminary Results... Antidumping Duty Administrative Review, 75 FR 7563 (February 22, 2010). This margin will apply to Chandan...

  6. 2011-12 IPEGS Training for School Administrators: Survey Results. Research Brief. Volume 1105

    ERIC Educational Resources Information Center

    Shneyderman, Aleksandr

    2012-01-01

    The survey results indicate that school administrators are familiar with the Instructional Performance Evaluation and Growth System (IPEGS); most rate themselves as proficient in conducting teacher observations. In addition, a majority of school administrators report a high degree of familiarity with both the IPEGS standards and the four-point…

  7. 77 FR 66580 - Certain Preserved Mushrooms From India: Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... India, 64 FR 8311 (February 19, 1999) (Mushroom Antidumping Duty Order), remains dispositive... International Trade Administration Certain Preserved Mushrooms From India: Preliminary Results of Antidumping... review of the antidumping duty order on certain preserved mushrooms (mushrooms) from India. The period...

  8. The mid-IR and near-IR interferometry of AGNs: key results and their implications

    NASA Astrophysics Data System (ADS)

    Kishimoto, M.

    2015-09-01

    Infrared interferometry has been very productive in directly probing the structure of AGNs at sub-pc scales. With tens of objects already probed in the mid-IR and near-IR, I will summarize the key results and im- plications from this direct exploration. The Keck interferometry in the near-IR and VLTI in the mid-IR shaped the luminosity dependence of the torus size and structure, while the latter also revealed an equatorial structure at several Rsub (dust sublimation radius), and a polar-elongated region at a few tens of Rsub. Notably, this polar component seems to dominate the compact mid-IR flux. This component can persuasively be attributed to a polar outflow. However, interferometry, through emissivity estimations, also indicates that it is not a UV-optically-thin cloud but participating in the obscuration of the nucleus. I will discuss how to accommodate all these facts to build a consistent picture.

  9. 77 FR 7129 - Certain Pasta From Italy: Final Results of the 2009 Countervailing Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ...: Preliminary Results of the 14th (2009) Countervailing Duty Administrative Review, 76 FR 48130 (August 8, 2011... Circumstances Review and Revocation, In Part, 76 FR 27634 (May 12, 2011). The merchandise subject to review is... Preliminary Results, 76 FR at 48135-36. Upon reevaluation of Measure 3.14 for these final results, we...

  10. 75 FR 39663 - Stainless Steel Bar From Brazil: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    .... prices to monthly home-market prices (see Preliminary Results, 75 FR at 12516), and we compared the home... Strip in Coils from Mexico; Final Results of Antidumping Duty Administrative Review, 74 FR 6365... Review, 75 FR 12514 (March 16, 2010) (Preliminary Results). We invited interested parties to comment...

  11. The Vital Role of Administrative Cost Allowances to Student Financial Aid Offices: Key Findings from NASFAA's Administrative Cost Allowance Survey, July 2011

    ERIC Educational Resources Information Center

    National Association of Student Financial Aid Administrators (NJ1), 2011

    2011-01-01

    The National Association of Student Financial Aid Administrators (NASFAA) recently conducted a survey on the 2009-10 award year Administrative Cost Allowances (ACA), which are funds used by colleges and universities to support operations and professional development. Specifically, ACA is often used in essential areas that support the day-to-day…

  12. The HIT-II Spherical Torus: Physics and Key Experimental Results

    NASA Astrophysics Data System (ADS)

    Redd, A. J.; Hamp, W. T.; Izzo, V. A.; Jarboe, T. R.; Nelson, B. A.; O'Neill, R. G.; Raman, R.; Sieck, P. E.; Smith, R. J.

    2004-11-01

    Discharges in the HIT-II spherical torus device [Redd et al., Phys. Plasmas 9, 2006 (2002)] can be driven by either Ohmic or Coaxial Helicity Injection (CHI) current drive. A new CHI operating regime has been explored, with toroidal plasma currents of up to 350 kA, I_p/I_TF ratios of up to 1.2, and internal probing data which may demonstrate the formation of a closed-flux core. The key to acheiving these results is the magnetic field shear in the CHI injector region, with a minimum shear necessary for current build-up. Ohmic plasma performance has also improved, with peak currents up to 300 kA, with and without transient CHI startup. The CHI startup technique [Raman et al., Phys. Plasmas 11, 2565 (2004)] provides more robust discharges, with a wider operating space and more efficient use of the transformer Volt-seconds, than unassisted Ohmic. Finally, CHI can be used to enhance an Ohmic plasma current without significantly degrading the quality of the discharge. Results will be presented for each HIT--II operating regime, including empirical performance scalings and applicable parametric operating spaces.

  13. Key results for the NRC`s Short Cracks in Piping and Piping Welds Research Program

    SciTech Connect

    Wilkowski, G.; Krishnaswamy, P.; Brust, F.

    1995-04-01

    The overall objective of the Short Cracks in Piping and Piping Welds Program is to verify and improve engineering analyses to predict the fracture behavior of circumferentially cracked pipe under quasi-static loading with particular attention to crack lengths typically used in LBB or flaw evaluation criteria. The USNCRC program at Battelle was initiated in March 1990 and is scheduled to be completed in December 1994. This paper discusses key results from the overall program with particular emphasis on the efforts since the last WRSIM meeting. The program consists of eight technical tasks as listed below: task 1 short through-wall-cracked (TWC) pipe evaluations; task 2 short surface-cracked (SC) pipe evaluations; task 3 bi-metallic weld crack evaluations; task 4 dynamic strain aging and crack instabilities; task 5 fracture evaluations of anisotropic pipe; task 6 crack-opening-area evaluations; task 7 NRCPIPE code improvements; task 8 additional efforts. Task 8 is a collection of new efforts initiated during the coarse of the program. A list of the full-scale pipe experiments in this program is given in Table 1. All of the experiments have been completed. The most recent accomplishments in each of the tasks listed above are discussed below. The details of all the results in the eight tasks are published in the semiannual reports as well as topical reports from the program.

  14. Impacts on irrigated agriculture of changes in electricity costs resulting from Western Area Power Administration`s power marketing alternatives

    SciTech Connect

    Edwards, B.K.; Flaim, S.J.; Howitt, R.E.; Palmer, S.C.

    1995-03-01

    Irrigation is a major factor in the growth of US agricultural productivity, especially in western states, which account for more than 85% of the nation`s irrigated acreage. In some of these states, almost all cropland is irrigated, and nearly 50% of the irrigation is done with electrically powered pumps. Therefore, even small increases in the cost of electricity could have a disproportionate impact on irrigated agriculture. This technical memorandum examines the impacts that could result from proposed changes in the power marketing programs of the Western Area Power Administration`s Salt Lake City Area Office. The changes could increase the cost of power to all Western customers, including rural municipalities and irrigation districts that rely on inexpensive federal power to pump water. The impacts are assessed by translating changes in Western`s wholesale power rate into changes in the cost of pumping water as an input for agricultural production. Farmers can adapt to higher electricity prices in many ways, such as (1) using different pumping fuels, (2) adding workers and increasing management to irrigate more efficiently, and (3) growing more drought-tolerant crops. This study projects several responses, including using less groundwater and planting fewer waterintensive crops. The study finds that when dependence on Western`s power is high, the cost of power can have a major effect on energy use, agricultural practices, and the distribution of planted acreage. The biggest percentage changes in farm income would occur (1) in Nevada and Utah (however, all projected changes are less than 2% of the baseline) and (2) under the marketing alternatives that represent the lowest capacity and energy offer considered in Western`s Electric Power Marketing Environmental Impact Statement. The aggregate impact on farm incomes and the value of total farm production would be much smaller than that suggested by the changes in water use and planted acreage.

  15. 66 FR 15399 - Electrolytic Manganese Dioxide From Greece: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2001-03-19

    ...: Electrolytic Manganese Dioxide from Greece, 66 FR 1950 (January 10, 2001) (Preliminary Results). Scope of... International Trade Administration Electrolytic Manganese Dioxide From Greece: Final Results of Antidumping Duty... antidumping duty order on electrolytic manganese dioxide from Greece. The review covers one...

  16. 75 FR 61128 - Polyethylene Retail Carrier Bags From Malaysia: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ..., as discussed in the Preliminary Results (75 FR at 33773-74), to Euro Plastics Malaysia Sdn. Bhd... Malaysia, 69 FR 34128 (June 18, 2004). These deposit requirements shall remain in effect until further...: Preliminary Results of Antidumping Duty Administrative Review, 75 FR 33772 (June 15, 2010)...

  17. 77 FR 40574 - Certain Frozen Warmwater Shrimp From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... Administrative Review and Preliminary No Shipment Determination, 77 FR 13082 (Mar. 5, 2012) (Preliminary Results... Preliminary Results, 77 FR at 13084-5, and the July 3, 2012, ``Issues and Decision Memorandum,'' which... to, whiteleg shrimp (Penaeus vannemei), banana prawn (Penaeus merguiensis), fleshy prawn...

  18. Factors Contributing to Financial Aid Administrators' Job Satisfaction: NASFAA 2008 Financial Aid Administrators' Job Satisfaction Survey Results

    ERIC Educational Resources Information Center

    National Association of Student Financial Aid Administrators (NJ1), 2008

    2008-01-01

    In what kind of job environment are financial aid administrators (FAA) currently working? How satisfied are they with their jobs? What motivates them and what factors are considered morale dampers? How are financial aid (FA) functions viewed by campus' top administrators? Does FA get similar respect and appreciation from their campus peer offices…

  19. North Atlantic Aerosol Properties and Direct Radiative Effects: Key Results from TARFOX and ACE-2

    NASA Technical Reports Server (NTRS)

    Russell, P. B.; Livingston, J. M.; Schmid, B.; Bergstrom, R. A.; Hignett, P.; Hobbs, P. V.; Durkee, P. A.; Condon, Estelle (Technical Monitor)

    1998-01-01

    Aerosol effects on atmospheric radiative fluxes provide a forcing function that can change the climate in potentially significant ways. This aerosol radiative Forcing is a major source of uncertainty in understanding the observed climate change of the past century and in predicting, future climate. To help reduce this uncertainty, the International Global Atmospheric Chemistry Project (IGAC) has endorsed a series of multiplatform aerosol field campaigns. The Tropospheric Aerosol Radiative Forcing Observational Experiment (TARFOX) and the second Aerosol Characterization Experiment (ACE-2) were the first IGAC campaigns to address the impact of anthropogenic aerosols. Both TARFOX and ACE-2 gathered extensive data sets on aerosol properties and radiative effects. TARFOX focused on the urban-industrial haze plume flowing from the eastern United States over the western Atlantic Ocean, whereas ACE-2 studied aerosols carried over the eastern Atlantic from both European urban/industrial and African mineral sources. These aerosols often have a marked influence on the top-of-atmosphere radiances measured by satellites, as illustrated in Figure 1. Shown there are contours of aerosol optical depth derived from radiances measured by the AVHRR sensor on the NOAA-11 satellite. The contours readily show that aerosols originating in North America, Europe, and Africa impact the radiative properties of air over the North Atlantic. However, the accurate derivation of flux chances, or radiative forcing, from the satellite-measured radiances or 'etrieved optical depths remains a difficult challenge. In this paper we summarize key Initial results from TARFOX and, to a lesser extent ACE-2, with a focus on those results that allow an improved assessment of the flux changes caused by North Atlantic aerosols at middle and high latitudes.

  20. North Atlantic Aerosol Properties and Direct Radiative Effects: Key Results from TARFOX and ACE-2

    NASA Technical Reports Server (NTRS)

    Russell, P. B.; Livingston, J. M.; Schmid, B.; Bergstrom, Robert A.; Hignett, P.; Hobbs, P. V.; Durkee, P. A.

    2000-01-01

    Aerosol effects on atmospheric radiative fluxes provide a forcing function that can change the climate In potentially significant ways. This aerosol radiative forcing is a major source of uncertainty in understanding the observed climate change of the past century and in predicting future climate. To help reduce this uncertainty, the International Global Atmospheric Chemistry Project (IGAC) has endorsed a series of multiplatform aerosol field campaigns. The Tropospheric Aerosol Radiative Forcing Observational Experiment (TARFOX) and the second Aerosol Characterization Experiment (ACE-2) were the first IGAC campaigns to address the impact of anthropogenic aerosols, Both TARFOX and ACE-2 gathered extensive data sets on aerosol properties and radiative effects, TARFOX focused on the urban-industrial haze plume flowing from the eastern United States over the western Atlantic Ocean, whereas ACE-2 studied aerosols carried over the eastern Atlantic from both European urban/industrial and African mineral sources. These aerosols often have a marked influence on the top-of-atmosphere radiances measured by satellites. Shown there are contours of aerosol optical depth derived from radiances measured by the AVHRR sensor on the NOAA-11 satellite. The contours readily show that aerosols originating in North America, Europe, and Africa impact the radiative properties of air over the North Atlantic. However, the accurate derivation of flux changes, or radiative forcing, from the satellite measured radiances or retrieved optical depths remains a difficult challenge. In this paper we summarize key initial results from TARFOX and, to a lesser extent, ACE-2, with a focus on those results that allow an improved assessment of the flux changes caused by North Atlantic aerosols at middle latitudes.

  1. 75 FR 43921 - Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... Polyester Staple Fiber From Taiwan: Preliminary Results of Antidumping Duty Administrative Review, 75 FR... Duties, 68 FR 23954 (May 6, 2003). The Department intends to issue assessment instructions directly to... Republic of Korea and Taiwan, 65 FR 33807 (May 25, 2000). These cash-deposit requirements shall remain...

  2. 78 FR 38938 - Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review; 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... Antidumping Duty Administrative Review; 2011-2012, 78 FR 17637 (March 22, 2013) (Preliminary Results). The... Duty Proceedings; Final Modification, 77 FR 8101, 8102 (February 14, 2012) (Final Modification). The... Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003) (Assessment Policy...

  3. 76 FR 40881 - Certain Frozen Warmwater Shrimp From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ... Shrimp from Thailand, 74 FR 5638 (Jan. 30, 2009) (Section 129 Determination). Cash Deposit Requirements... Duty Administrative Review and Preliminary No Shipment Determination, 76 FR 12033 (Mar. 4, 2011... Thai Food Product. See Preliminary Results, 76 FR at 12035-12036. As we stated in the...

  4. 78 FR 72633 - Chlorinated Isocyanurates From Spain: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Administrative Review; 2011-12, 78 FR 41367 (July 10, 2013) (``Preliminary Results'') \\2\\ Ercros formerly... Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003) (Assessment Policy... Sales at Less Than Fair Value, 70 FR 24506 (May 10, 2005). Notification to Importers This notice...

  5. 75 FR 51440 - Solid Urea from the Russian Federation: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... From the Russian Federation: Preliminary Results of Antidumping Duty Administrative Review, 75 FR 19610... and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003...; Final Determination of Sales at Less Than Fair Value, 52 FR 19557 (May 26, 1987). Following the...

  6. 78 FR 67335 - Solid Urea From the Russian Federation: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... Duty Administrative Review; 2011-2012, 78 FR 46571 (August 1, 2013) (Preliminary Results). The... in Certain Antidumping Duty Proceedings; Final Modification, 77 FR 8101, 8102 (February 14, 2012... clarification, see Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68...

  7. 77 FR 42273 - Solid Urea From the Russian Federation: Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... Revocation in Part, 76 FR 53404 (August 26, 2011). \\3\\ See Solid Urea From the Russian Federation: Extension of Time Limit for Preliminary Results of Antidumping Duty Administrative Review, 77 FR 17410 (March...: Final Modification, 77 FR 8101 (February 14, 2012) (``Final Modification for Reviews''). When...

  8. 76 FR 66690 - Solid Urea From the Russian Federation: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... of Antidumping Duty Administrative Review, 76 FR 35405 (June 17, 2011) (Preliminary Results). On... Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003... Sales at Less Than Fair Value, 52 FR 19557, 19561 (May 26, 1987). Following the break-up of the...

  9. 75 FR 62100 - Purified Carboxymethylcellulose From Mexico: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... of Antidumping Duty Administrative Review, 75 FR 33775 (June 15, 2010) (Preliminary Results). The... Duties, 68 ] FR 23954 (May 6, 2003). This clarification will apply to entries of subject merchandise... from Mexico, 70 FR 28280 (May 17, 2005). These deposit requirements shall remain in effect...

  10. 76 FR 42113 - Purified Carboxymethylcellulose From Mexico: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... Antidumping Duty Administrative Review, 76 FR 20313 (April 12, 2011) (Preliminary Results). The review covers... Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003). This clarification will apply to... Carboxymethylcellulose From Mexico and Sweden: Revocation of Antidumping Duty Orders, 76 FR 29194 (May 20,...

  11. 78 FR 79662 - Stainless Steel Plate in Coils From Belgium: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...: Preliminary Results of Antidumping Duty Administrative Review; 2011-2012, 78 FR 34644 (June 10, 2013..., Italy, the Republic of Korea, South Africa, and Taiwan, 64 FR 27756 (May 21, 1999); Notice of Amended... Korea, South Africa, and Taiwan, 68 FR 11520 (March 11, 2003); Notice of Amended Antidumping Duty...

  12. 78 FR 29702 - Ball Bearings and Parts Thereof From Germany: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... Results of Sunset Reviews and Revocation of Antidumping Duty Orders, 76 FR 57019, (September 15, 2011... Antidumping Duty Administrative Review and Partial Rescission; 2011- 2011, 78 FR 9764 (February 11, 2013... Duty Proceedings; Final Modification, 77 FR 8101 (February 14, 2012) (Final Modification)....

  13. 75 FR 38076 - Carbazole Violet Pigment 23 from India: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... Value and Antidumping Duty Order: Carbazole Violet Pigment 23 From India, 69 FR 77988 (December 29, 2004... Pigment 23 from India: Preliminary Results of Antidumping Duty Administrative Review, 74 FR 68038...: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003). The Department intends to issue...

  14. 77 FR 73615 - Lightweight Thermal Paper From Germany; Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... Thermal Paper from Germany and the People's Republic of China, 73 FR 70959 (November 24, 2008) (Orders...: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003). Assessment of Antidumping Duties We intend to... International Trade Administration Lightweight Thermal Paper From Germany; Preliminary Results of...

  15. 78 FR 12034 - Certain Preserved Mushrooms From India: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... Preserved Mushrooms: Preliminary Results of Antidumping Duty Administrative Review; 2011-2012, 77 FR 66580... Fair Value and Antidumping Duty Order: Certain Preserved Mushrooms From India, 64 FR 8311 (February 19...'' mushrooms, which are prepared or preserved by means of vinegar or acetic acid, but may contain oil or...

  16. 76 FR 1599 - Stainless Steel Bar From Brazil: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... Antidumping Duty Administrative Review, 75 FR 67689 (November 3, 2010) (Preliminary Results). We invited... Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003... Less Than Fair Value: Stainless Steel Bar From Brazil, 59 FR 66914 (December 28, 1994). These...

  17. 64 FR 62169 - Electrolytic Manganese Dioxide From Greece: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    1999-11-16

    ... Administrative Review: Electrolytic Manganese Dioxide from Greece, 64 FR 25008 (preliminary results). Kerr-McGee... sales in the Final Determination of Sales at Less Than Fair Value; Fresh Salmon From Chile, 63 FR 31418... FR 31418 (June 9, 1998). That situation simply does not exist in this case, where both...

  18. 75 FR 56989 - Magnesium Metal From the Russian Federation: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... Duty Administrative Review, 75 FR 26922 (May 13, 2010) (Preliminary Results). We invited interested... Magnesium in Granular Form From the People's Republic of China, 66 FR 49345 (September 27, 2001), Notice of Final Determination of Sales at Less Than Fair Value: Pure Magnesium From Israel, 66 FR 49349...

  19. 76 FR 56396 - Magnesium Metal from the Russian Federation: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... of Antidumping Duty Administrative Review, 76 FR 26247 (May 6, 2011) (Preliminary Results). We... FR 13128 (March 10, 2011). The subject merchandise includes the following pure and alloy magnesium... Granular Form From the People's Republic of China, 66 FR 49345 (September 27, 2001), Notice of...

  20. 78 FR 22232 - Certain Lined Paper Products From India: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... of Countervailing Duty Orders: Certain Lined Paper Products from India and Indonesia, 71 FR 56949... Products from India and Indonesia, 71 FR 56949 (September 28, 2006). Analysis of Comments Received All... Duty Administrative Review; 2010-2011, 77 FR 61381 (October 9, 2012) (Preliminary Results),...

  1. 78 FR 22845 - Certain Lined Paper Products From India: Final Results of Countervailing Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... Countervailing Duty Orders: Certain Lined Paper Products from India and Indonesia, 71 FR 56949 (September 28... Administrative Review; Calendar Year 2010, 77 FR 61742 (October 11, 2012) (Preliminary Results). \\2\\ See Issues...\\ Lined Paper Order, 71 FR at 56950-51. Analysis of Comments Received All issues raised in the case...

  2. 76 FR 50176 - Certain Orange Juice from Brazil: Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... order includes certain orange juice for transport and/or further manufacturing, produced in two... Brazil. See Antidumping Duty Order; Frozen Concentrated Orange Juice from Brazil, 52 FR 16426 (May 5... Administrative Review, 74 FR 40167 (Aug. 11, 2009); and Certain Orange Juice from Brazil: Final Results...

  3. 78 FR 34648 - Citric Acid and Certain Citrate Salts: Preliminary Results of Countervailing Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... International Trade Administration Citric Acid and Certain Citrate Salts: Preliminary Results of Countervailing... review of the countervailing duty (CVD) order on citric acid and citrate salts from the People's Republic... (202) 482-1503. Scope of the Order The merchandise subject to the order is citric acid and...

  4. 76 FR 29192 - Honey From Argentina: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... established in the LTFV investigation. See Notice of Antidumping Duty Order; Honey From Argentina, 66 FR 63672... Argentina: Preliminary Results of Antidumping Duty Administrative Review, 76 FR 2655 (January 14, 2011... to the Tariff Act of 1930, As Amended, 70 FR 24533 (May 10, 2005). Period of Review The POR...

  5. 77 FR 36253 - Honey From Argentina: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Notice of Antidumping Duty Order; Honey From Argentina, 66 FR 63672 (December 10, 2001). These deposit... Administrative Review, 77 FR 1458 (January 10, 2012) (Preliminary Results). DATES: Effective Date: June 18, 2012... assessment regulation on May 6, 2003 (68 FR 23954). This clarification will apply to entries of...

  6. 75 FR 67689 - Stainless Steel Bar From Brazil: Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Brazil. See Antidumping Duty Orders: Stainless Steel Bar from Brazil, India and Japan, 60 FR 9661... Steel Bar From Brazil: Preliminary Results of Antidumping Duty Administrative Review, 74 FR 10022 (March... Less Than Fair Value: Stainless Steel Bar From Brazil, 59 FR 66914 (December 28, 1994). These...

  7. 77 FR 48966 - Saccharin From the People's Republic of China: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... metalworking fluids. There are four primary chemical compositions of saccharin: (1) Sodium saccharin (American Chemical Society Chemical Abstract Service (``CAS'') Registry 128-44-9); (2) calcium saccharin (CAS...: Preliminary Results of Antidumping Duty Administrative Review and Intent To Rescind in Part, 77 FR...

  8. 78 FR 9670 - Polyethylene Terephthalate Film, Sheet, and Strip From India: Final Results of Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet, and Strip From India: Final Results... order on polyethylene terephthalate film (PET Film) from India.\\1\\ This review covers three respondents, Jindal Poly Films Ltd (Jindal), Polyplex Corporation Ltd. (Polyplex), and SRF Limited (SRF),...

  9. 76 FR 41203 - Certain Frozen Warmwater Shrimp From India: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... FR 12025 (Mar. 4, 2011) (Preliminary Results). On March 21, 2011, in response to a request from the... to, whiteleg shrimp (Penaeus vannemei), banana prawn (Penaeus merguiensis), fleshy prawn (Penaeus... Initiation of Antidumping Duty Administrative Reviews, 76 FR 18157 (Apr. 1, 2011) (Initiation Notice)....

  10. Ready or Not: A Report of the 1979 Statewide Readiness Test Administration and Results.

    ERIC Educational Resources Information Center

    Meredith, Vana H.; And Others

    The selection, administration and results of a statewide school readiness test in South Carolina are described in this report. As one component of South Carolina's Basic Skills Assessment Program, the "Cognitive Skills Assessment Battery" (CSAB) was chosen to distinguish those children who are ready for the formal first grade curriculum from those…

  11. 78 FR 11817 - Purified Carboxymethylcellulose From Finland: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... Carboxymethylcellulose from Finland: Notice of Preliminary Results of Antidumping Duty Administrative Review, 77 FR 47036... Antidumping Duties, 68 FR 23954 (May 6, 2003). This clarification will apply to entries of subject merchandise... Sweden, 70 FR 39734 (July 11, 2005). These deposit requirements, when imposed, shall remain in...

  12. Participant survey results from the Starting Hizentra Administration with Resources and Education (SHARE) program.

    PubMed

    Duff, Carla; Riley, Patty; Zampelli, Annette; Murphy, Elyse

    2014-01-01

    Increased use of specialized infusion therapies has necessitated training of health care providers and patients. The Starting Hizentra Administration with Resources and Education (SHARE) program provided 709 US participants with information to educate patients with primary immunodeficiency disease (PIDD) on self-administration of 20% subcutaneous immunoglobulin (SCIG). Postprogram surveys assessed participants' experience and opinion of 20% SCIG. The most frequent questions about 20% SCIG regarded subcutaneous challenges (29%). Participants stated that all attributes of SCIG were beneficial (51%), and they expressed interest in future programs on non-PIDD diseases (26%). Survey results will assist in future SHARE and other relevant educational program optimization.

  13. Key questions resulting from the JUPITER trial assessing cardiovascular disease intervention with rosuvastatin

    PubMed Central

    Rashid, Shirya

    2009-01-01

    This paper presents an analysis of the recently published Justification for the Use of statins in Prevention (JUPITER: an intervention trial evaluating rosuvastatin) trial, which tested the statin rosuvastatin in apparently healthy individuals with no prior cardiovascular (CVD) disease and with normal plasma low density lipoprotein (LDL) cholesterol concentrations but with raised plasma high sensitivity C-reactive protein (hsCRP) levels. The rate of the combined primary CVD endpoint was significantly reduced in the treatment arm after a median of under 2 years. The JUPITER trial is distinct from previous studies examining statin use in primary prevention groups because the target group for drug therapy was apparently healthy men and women at low or intermediate risk for developing CVD. On the basis of JUPITER’s findings, there are key questions that should be assessed on the therapeutic intervention of CVD regarding: the primary prevention groups that should be targeted for statin therapy, the utility of targets in addition to plasma LDL cholesterol levels, and the need to consider the metabolic state of individuals targeted for therapy (including the presence of obesity and inflammation). The conclusion from the current analysis is that the JUPITER results warrant further LDL cholesterol lowering than is currently targeted in primary prevention groups that have a pre-existing condition or lifestyle that elevates CVD risk but still do not have a high global CVD risk (as assessed with current algorithms). This group is not captured in current widely used CVD risk calculations, however, with the identification of useful biomarkers, such as hsCRP, this group can be better identified and targeted for intervention. PMID:21160575

  14. Analyzing Ethics in the Administration of Interscholastic Sports: Three Key Gender-Related Ethical Dilemmas Faced by Educational Leaders

    ERIC Educational Resources Information Center

    Whisenant, Warren A.; Pedersen, Paul M.; Clavio, Galen

    2010-01-01

    Athletic administrators and decision makers within interscholastic athletics are expected to embrace a code of ethics that serves as a set of rules to guide their professional behavior. Included within this code are areas of controversy that present gender-related ethical dilemmas for administrators. Three specific ethical dilemmas involve (1)…

  15. Keying Results on the CELT-Structure Test to U.S. Grade Level Instructional Materials

    ERIC Educational Resources Information Center

    Moran, Ross T.

    1978-01-01

    It would be beneficial for ESL instructors to know the U.S. grade equivalent English ability of their students for placement purposes, especially if their instructional materials are keyed for U.S. classrooms. For this purpose, the Stanford Intermediate Level I Reading Comprehension Test was compared with the CELT-Structure Test. (Author/RM)

  16. Monitoring the Future: National Results on Adolescent Drug Use. Overview of Key Findings, 2002.

    ERIC Educational Resources Information Center

    Michigan Univ., Ann Arbor. Inst. for Social Research.

    This report presents an overview of the key findings from the Monitoring the Future 2002 nationwide survey of 8th, 10th, and 12th grade students. A particular emphasis is placed on recent trends in the use of licit and illicit drugs. Trends in the levels of perceived risk and personal disapproval associated with each drug--which this study has…

  17. Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2001.

    ERIC Educational Resources Information Center

    Johnston, Lloyd D.; O'Malley, Patrick M.; Bachman, Jerald G.

    This report presents an overview of the key findings from the Monitoring the Future 2001 nationwide survey of 8th, 10th, and 12th grade students. A particular emphasis is placed on recent trends in the use of licit and illicit drugs. Trends in the levels of perceived risk and personal disapproval associated with each drug--which this study has…

  18. Gemini Planet Imager Exoplanet Survey: Key Results Two Years Into The Survey

    NASA Astrophysics Data System (ADS)

    Marchis, Franck; Rameau, Julien; Nielsen, Eric L.; De Rosa, Robert J.; Esposito, Thomas; Draper, Zachary H.; Macintosh, Bruce; Graham, James R.; GPIES

    2016-10-01

    The Gemini Planet Imager Exoplanet Survey (GPIES) is targeting 600 young, nearby stars using the GPI instrument. We report here on recent results obtained with this instrument from our team.Rameau et al. (ApJL, 822 2, L2, 2016) presented astrometric monitoring of the young exoplanet HD 95086 b obtained with GPI between 2013 and 2016. Efficient Monte Carlo techniques place preliminary constraints on the orbital parameters of HD 95086 b. Under the assumption of a coplanar planet–disk system, the periastron of HD 95086 b is beyond 51 AU. Therefore, HD 95086 b cannot carve the entire gap inferred from the measured infrared excess in the SED of HD 95086. Additional photometric and spectroscopic measurements reported by de Rosa et al. (2016, apJ, in press) showed that the spectral energy distribution of HD 95086 b is best fit by low temperature (T~800-1300 K), low surface gravity spectra from models which simulate high photospheric dust content. Its temperature is typical to L/T transition objects, but the spectral type is poorly constrained. HD 95086 b is an important exoplanet to test our models of atmospheric properties of young extrasolar planets.Direct detections of debris disk are keys to infer the collisional past and understand the formation of planetary systems. Two debris disks were recently studied with GPI:- Draper et al. (submitted to ApJ, 2016) show the resolved circumstellar debris disk around HD 111520 at a projected range of ~30-100 AU using both total and polarized H-band intensity. Structures in the disks such as a large brightness asymmetry and symmetric polarization fraction are seen. Additional data would confirm if a large disruption event from a stellar fly-by or planetary perturbations altered the disk density- Esposito et al. (submitted to ApJ, 2016) combined Keck NIRC2 data taken at 1.2-2.3 microns and GPI 1.6 micron total intensity and polarized light detections that probes down to projected separations less than 10 AU to show that the HD

  19. 76 FR 76144 - Notice of Amended Final Results of the Antidumping Duty Administrative Review of Certain Lined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... China: Notice of Final Results of the Antidumping Duty Administrative Review, 74 FR 17160 (April 14... Administrative Review of Certain Lined Paper Products from the People's Republic of China, 74 FR 68036 (December... Final Results of Administrative Review Pursuant to Court Decision, 76 FR 53116 (August 25, 2011)....

  20. 75 FR 20812 - Silicon Metal from Brazil: Amended Final Results of Administrative Review Pursuant to Court Decision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... Metal from Brazil for the period of review beginning July 1, 1996, through June 30, 1997. See Silicon Metal from Brazil: Notice of Final Results of Antidumping Duty Administrative Review, 64 FR 6305... International Trade Administration Silicon Metal from Brazil: Amended Final Results of Administrative...

  1. Mont Terri Underground Rock Laboratory, Switzerland-Research Program And Key Results

    NASA Astrophysics Data System (ADS)

    Nussbaum, C. O.; Bossart, P. J.

    2012-12-01

    Argillaceous formations generally act as aquitards because of their low hydraulic conductivities. This property, together with the large retention capacity of clays for cationic contaminants and the potential for self-sealing, has brought clay formations into focus as potential host rocks for the geological disposal of radioactive waste. Excavated in the Opalinus Clay formation, the Mont Terri underground rock laboratory in the Jura Mountains of NW Switzerland is an important international test site for researching clay formations. Research is carried out in the underground facility, which is located adjacent to the security gallery of the Mont Terri motorway tunnel. Fifteen partners from European countries, USA, Canada and Japan participate in the project. The objectives of the research program are to analyze the hydrogeological, geochemical and rock mechanical properties of the Opalinus Clay, to determine the changes induced by the excavation of galleries and by heating of the rock formation, to test sealing and container emplacement techniques and to evaluate and improve suitable investigation techniques. For the safety of deep geological disposal, it is of key importance to understand the processes occurring in the undisturbed argillaceous environment, as well as the processes in a disturbed system, during the operation of the repository. The objectives are related to: 1. Understanding processes and mechanisms in undisturbed clays and 2. Experiments related to repository-induced perturbations. Experiments of the first group are dedicated to: i) Improvement of drilling and excavation technologies and sampling methods; ii) Estimation of hydrogeological, rock mechanical and geochemical parameters of the undisturbed Opalinus Clay. Upscaling of parameters from laboratory to in situ scale; iii) Geochemistry of porewater and natural gases; evolution of porewater over time scales; iv) Assessment of long-term hydraulic transients associated with erosion and thermal

  2. [Safety evaluation of new anticancer chemotherapy administration system: compared to the results from a former study-].

    PubMed

    Terui, Kentaro; Okajima, Hiroko; Nakajima, Yasuaki

    2011-09-01

    Anticancer drugs can cause genotoxicities such as mutagenicity and/or chromosomal abnormalities, and/or toxicities, such as fetal malformation or cancer. In recent years, the health risks to health care workers who handle anticancer drugs at work has been considered. In 2009, we researched the exposure risk of anticancer chemotherapy in a nursing administration area using fluorescein (which was used as a contamination detection agent), to identify the problem. The result of this investigation showed that three types of events caused the risk of toxic exposure: 1 . Priming with anticancer drugs; 2 . leakage from the infusion bag when removing the spike from IV containers(exchanging of IV bottle); and 3 . removal of the IV line from the patient without rinsing with normal saline. Taking measures to cope with those problems, we have introduced our new anticancer chemotherapy administration system for prevention against toxic exposure. This system was evaluated in a leak-proof infusion bag by using fluorescein, which was used in our former study. As a result, a leakage reaction has not been detected in any handling events. Although visible leakage of fluorescein is an effective way to identify the exposure risk in an administration area, the analysis is not clear, objective or numerical. Therefore, this system's safety should be assessed with a numerical analysis of the leakage reaction in a further study, such as an environmental contamination research.

  3. Are the American Psychological Association's Detainee Interrogation Policies Ethical and Effective?: Key Claims, Documents, and Results.

    PubMed

    Pope, Kenneth S

    2011-01-01

    After 9-11, the United States began interrogating detainees at settings such as Abu Ghraib, Bagram, and Guantanamo. The American Psychological Association (APA) supported psychologists' involvement in interrogations, adopted formal policies, and made an array of public assurances. This article's purpose is to highlight key APA decisions, policies, procedures, documents, and public statements in urgent need of rethinking and to suggest questions that may be useful in a serious assessment, such as, "However well intended, were APA's interrogation policies ethically sound?"; "Were they valid, realistic, and able to achieve their purpose?"; "Were other approaches available that would address interrogation issues more directly, comprehensively, and actively, that were more ethically and scientifically based, and that would have had a greater likelihood of success?"; and "Should APA continue to endorse its post-9-11 detainee interrogation policies?"

  4. Statewide Administration of the ACT: A Key Component in Improving Student Access to College and Work. Case Study

    ERIC Educational Resources Information Center

    ACT, Inc., 2009

    2009-01-01

    In recent years there has been an increasing focus among states on the importance of preparing all students for college and work. Statewide administration of the ACT provides all students, including those who have never considered college as an option, with the opportunity to identify academic strengths and weaknesses, explore educational and…

  5. Key Recent Scientific Results from the Opportunity Rover's Exploration of Cape Tribulation, Endeavour Crater, Mars

    NASA Astrophysics Data System (ADS)

    Arvidson, R. E.; Squyres, S. W.; Gellert, R.; Herkenhoff, K. E.; Mittlefehldt, D. W.; Crumpler, L. S.; McLennan, S. M.; Farrand, W. H.; Jolliff, B. L.; Morris, R. V.

    2015-12-01

    The Opportunity Rover is in its 11th year of exploration, currently exploring the Cape Tribulation rim segment of the ~22 km wide Noachian Endeavour Crater and its tilted and fractured outcrops. A key target for Opportunity's measurements has been the Spirit of Saint Louis crater (SoSL), which is ~25 m wide, oval in plan view, shallow, flat-floored, and has a slightly raised rim. SoSL crater is surrounded by an apron of bright, polygonally-shaped outcrops and is superimposed on a gentle swale in Cape Tribulation. Rocks in a thin reddish zone on the rim are enriched in hematite, Si, and Ge, and depleted in Fe, relative to surrounding rocks. Apron rocks include an outcrop also enriched in Si and Ge, and slightly depleted in Fe. In general rocks in the crater and apron have elevated S levels relative to Shoemaker formation breccias, tracking values observed in the Cook Haven (gentle swale superimposed on Murray Ridge and site of Opportunity's 5th winter site) and the Hueytown fracture (running perpendicular to Cape Tribulation) outcrops. SoSL crater lies just to the west of Marathon Valley, a key target for exploration by Opportunity because five separate CRISM observations indicate the presence of Fe/Mg smectites on the upper valley floor. Opportunity data show that low relief, relatively bright, wind-scoured outcrops dominate the valley floor where not covered by scree and soil shed from surrounding walls. Initial reconnaissance shows that the outcrops are breccias with compositions similar to the typical SoSL crater apron and floor rocks, although only the very upper portion of the valley has been explored as of August 2015. Pervasive but modest aqueous alteration of Endeavour's rim is implied by the combination of CRISM and Opportunity data, providing insight into early aqueous processes dominated in this location by relatively low water to rock ratios, and at least in part associated with enhanced fluid flow along fractures.

  6. 75 FR 49888 - Notice of Extension of Time Limit for Final Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... and Partial Rescission of the 2008-2009 Administrative Review, 75 FR 18812 (April 13, 2010). The... Administrative Review: Certain Tissue Paper Products from the People's Republic of China AGENCY: Import... preliminary results of the administrative review of the antidumping duty order on certain tissue...

  7. Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study

    PubMed Central

    Vincent, Jean-Louis; Sakr, Yasser; Reinhart, Konrad; Sprung, Charles L; Gerlach, Herwig; Ranieri, V Marco

    2005-01-01

    Introduction Albumin administration in the critically ill has been the subject of some controversy. We investigated the use of albumin solutions in European intensive care units (ICUs) and its relationship to outcome. Methods In a cohort, multicenter, observational study, all patients admitted to one of the participating ICUs between 1 May and 15 May 2002 were followed up until death, hospital discharge, or for 60 days. Patients were classified according to whether or not they received albumin at any time during their ICU stay. Results Of 3,147 admitted patients, 354 (11.2%) received albumin and 2,793 (88.8%) did not. Patients who received albumin were more likely to have cancer or liver cirrhosis, to be surgical admissions, and to have sepsis. They had a longer length of ICU stay and a higher mortality rate, but were also more severely ill, as manifested by higher simplified acute physiology score (SAPS) II and sequential organ failure assessment (SOFA) scores than the other patients. A Cox proportional hazard model indicated that albumin administration was significantly associated with decreased 30-day survival. Moreover, in 339 pairs matched according to a propensity score, ICU and hospital mortality rates were higher in the patients who had received albumin than in those who had not (34.8 versus 20.9% and 41.3 versus 27.7%, respectively, both p < 0.001). Conclusion Albumin administration was associated with decreased survival in this population of acutely ill patients. Further prospective randomized controlled trials are needed to examine the effects of albumin administration in sub-groups of acutely ill patients. PMID:16356223

  8. Key Recent Scientific Results from the Opportunity Rover's Exploration of Endeavour Crater, Mars

    NASA Technical Reports Server (NTRS)

    Arvidson, R. E.; Squyres, S. W.; Gellert, R.; Herkenhoff, K.; Mittlefehldt, D.; Crumpler, L.; McLennan, S.; Farrand, W. H.; Joliff, B. L.; Morris, R. V.

    2015-01-01

    The Opportunity Rover is currently in its 11th year of operations, exploring the rim of the approximately 22 km wide Noachian-age Endeavour Crater. Opportunity spent its 5th winter season in Cook Haven, a gentle swale along Murray Ridge. Two small rocks serendipitously overturned by rover wheel motions show evidence for aqueous precipitation of sulfates, and interaction with a strong oxidant (e.g., O2) to form a thin, high valence state Mn oxide coating. After the winter, Opportunity headed south to Cape Tribulation and explored Shoemaker formation impact breccias, finding numerous Ca-sulfate veins cutting across outcrops. A key target for Opportunity's measurements has been the Spirit of Saint Louis crater (SoSL), which is approximately 25 m wide, oval in plan view, shallow, flat-floored, and has a slightly raised rim. SoSL crater is surrounded by an apron of bright, polygonally-shaped outcrops and is superimposed on a gentle swale in Cape Tribulation. Rocks in a thin reddish zone on the rim are enriched in hematite, Si, and Ge, and depleted in Fe, relative to surrounding rocks. Apron rocks include an outcrop also enriched in Si and Ge, and slightly depleted in Fe. In general rocks in the crater and apron have elevated S relative to Shoemaker formation breccias, tracking values observed in the Cook Haven and the Hueytown (fracture running perpendicular to Cape Tribulation) outcrops. SoSL crater lies just to the west of Marathon Valley, a key target for exploration by Opportunity because five separate CRISM observations indicate the presence of Fe/Mg smectites on the upper valley floor. Opportunity data show that low relief, relatively bright polygonal outcrops dominate the valley floor where not covered by scree and soil shed from surrounding walls. Initial reconnaissance shows that the outcrops are breccias with compositions similar to the typical SoSL crater apron and floor rocks, although only the very upper portion of the valley has been explored as of August

  9. Building an Evaluative Culture: The Key to Effective Evaluation and Results Management

    ERIC Educational Resources Information Center

    Mayne, John

    2009-01-01

    As many reviews of results-based performance systems have noted, a weak evaluative culture in an organization undermines attempts at building an effective evaluation and/or results management regime. This article sets out what constitutes a strong evaluative culture where information on performance results is deliberately sought in order to learn…

  10. Update of Ulysses FSAR results using updated NASA (National Aeronautics and Space Administration) probabilities

    SciTech Connect

    Not Available

    1990-05-18

    The mission risk results reported in the Ulysses Final Safety Analysis Report (FSAR) issued on March 14, 1990, were based on initiating accident probabilities the National Aeronautics and Space Administration (NASA) provided to the Department of Energy (DOE) on July 13, 1988. These probabilities were provided in terms of ranges; the geometric mean of these ranges were used in the development and presentation of the results in the FSAR for source terms, radiological consequences and risks. Subsequent to the issuance of the FSAR, DOE received a revised set of probabilities from NASA. These probabilities were presented in terms of distributions for each initiating accident and characterized by a mean and cumulative percentile values. NASA recommended that DOE use the updated probabilities to update the Ulysses FSAR results. Accordingly, at the request of DOE, this letter report has been prepared to evaluate the changes in the Ulysses FSAR results when the updated mean probabilities are used.

  11. 77 FR 69793 - Certain Pasta From Italy; Final Results of Countervailing Duty Administrative Review; 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE... Review; 2010 AGENCY: Import Administration, International Trade Administration, Department of Commerce. SUMMARY: On August 1, 2012, the Department of Commerce (the ``Department'') published in the...

  12. An animal model of schizophrenia based on chronic LSD administration: old idea, new results.

    PubMed

    Marona-Lewicka, Danuta; Nichols, Charles D; Nichols, David E

    2011-09-01

    Many people who take LSD experience a second temporal phase of LSD intoxication that is qualitatively different, and was described by Daniel Freedman as "clearly a paranoid state." We have previously shown that the discriminative stimulus effects of LSD in rats also occur in two temporal phases, with initial effects mediated by activation of 5-HT(2A) receptors (LSD30), and the later temporal phase mediated by dopamine D2-like receptors (LSD90). Surprisingly, we have now found that non-competitive NMDA antagonists produced full substitution in LSD90 rats, but only in older animals, whereas in LSD30, or in younger animals, these drugs did not mimic LSD. Chronic administration of low doses of LSD (>3 months, 0.16 mg/kg every other day) induces a behavioral state characterized by hyperactivity and hyperirritability, increased locomotor activity, anhedonia, and impairment in social interaction that persists at the same magnitude for at least three months after cessation of LSD treatment. These behaviors, which closely resemble those associated with psychosis in humans, are not induced by withdrawal from LSD; rather, they are the result of neuroadaptive changes occurring in the brain during the chronic administration of LSD. These persistent behaviors are transiently reversed by haloperidol and olanzapine, but are insensitive to MDL-100907. Gene expression analysis data show that chronic LSD treatment produced significant changes in multiple neurotransmitter system-related genes, including those for serotonin and dopamine. Thus, we propose that chronic treatment of rats with low doses of LSD can serve as a new animal model of psychosis that may mimic the development and progression of schizophrenia, as well as model the established disease better than current acute drug administration models utilizing amphetamine or NMDA antagonists such as PCP.

  13. 76 FR 48125 - Certain Pasta From Italy: Notice of Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ...: Certain Pasta From Italy, 61 FR 38547 (July 24, 1996). \\2\\ See Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Opportunity To Request Administrative Review, 75 FR 38074 (July 1... Countervailing Duty Administrative Reviews and Deferral of Initiation of Administrative Review, 75 FR...

  14. 77 FR 34346 - Fresh Garlic from the People's Republic of China: Final Results of the 2009-2010 Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ...: Partial Final Results and Partial Final Rescission of the 2009-2010 Administrative Review, 77 FR 11486... FR 76375 (December 7, 2011) (Preliminary Results). On December 20, 2011, in response to Xinboda's and... Results of the 2009-2010 Administrative Review, 77 FR 17409 (March 26, 2012). At the request of Xinboda,...

  15. Determination of ideal-gas enthalpies of formation for key compounds: The 1988 project results

    SciTech Connect

    Steele, W.V.; Chirico, R.D.; Nguyen, A.; Hossenlopp, I.A.; Smith, N.K.

    1990-07-01

    The results of a study aimed at improvement of group contribution methodology for estimation of thermodynamic properties of organic substances are reported. Specific weakness where particular group-contribution terms were unknown, or estimated because of lack of experimental data, are addressed by experimental studies of enthalpies of combustion in the condensed phase and vapor-pressure measurements. Ideal-gas enthalpies of formation are reported for 3-methylbuta-1,2-diene; 2,5-dimethylhexa-2,4-diene; acetaldoxime; N,N-diethylhydroxylamine; 1-methylpyrrolidin-2-one; and phenanthrene. Solid and liquid-phase enthalpies of formation at 298.15 K are determined for benzamide. Ring corrections, group terms, and next-nearest-neighbor interaction terms useful in the application of group contribution correlations are derived. 54 refs., 2 figs., 21 tabs.

  16. Determination of ideal-gas enthalpies of formation for key compounds: The 1988 project results

    NASA Astrophysics Data System (ADS)

    Steele, W. V.; Chirico, R. D.; Nguyen, A.; Hossenlopp, I. A.; Smith, N. K.

    1990-07-01

    The results of a study aimed at improvement of group contribution methodology for estimation of thermodynamic properties of organic substances are reported. Specific weakness where particular group-contribution terms were unknown, or estimated because of lack of experimental data, are addressed by experimental studies of enthalpies of combustion in the condensed phase and vapor pressure measurements. Ideal-gas enthalpies of formation are reported for 3-methylbuta 1,2-diene; 2,5-dimethylhexa 2,4-diene; acetaldoxime; N,N-diethyl hydroxylamine; 1-methylpyrrolidin-2-one; and phenanthrene. Solid and liquid phase enthalpies of formation at 298.15 K are determined for benzamide. Ring corrections, group terms, and next-nearest-neighbor interaction terms useful in the application of group contribution correlations are derived.

  17. Canine leishmaniasis: the key points for qPCR result interpretation

    PubMed Central

    2011-01-01

    Background Diagnosis and follow up of CanL is difficult since the range of clinical signs is varied and seroprevalence is high in endemic areas. The aims of this study were: i) demonstrate the advantages of Leishmania qPCR to diagnose and control CanL and highlight its prognostic value and ii) propose guidelines for tissue selection and infection monitoring. Findings This study included 710 dogs living in an endemic area of leishmaniasis. Forty percent (285/710) exhibited clinical signs consistent with CanL. Infection was detected in 36.3% (258/710) of the dogs of which 4.5% (32/710) were detected by qPCR, 16.2% (115/710) detected by ELISA and 15.6% (111/710) tested positive for both tests. Only 17.9% (127/710) of the dogs were classified sick (affected) with CanL. All symptomatic dogs with medium or high ELISA titers were qPCR-positive in blood samples. All dogs with inconclusive or low ELISA results with high or medium qPCR parasitemia values developed the disease. Seventy one percent of asymptomatic ELISA-positive dogs confirmed by qPCR (medium to high parasitemia) developed the disease. Bone marrow or lymph node aspirate should be selected to ensure the absence of the parasite in asymptomatic dogs: 100-1,000 parasites/ml in bone marrow are detectable in blood, whereas lower parasite loads are usually negative. Almost 10% of negative samples in blood were positive in conjunctival swabs. Conclusions Because qPCR allows parasite quantification, it is an effective tool to confirm a diagnosis of CanL in (i) cases of inconclusive ELISA results, (ii) when the dog has not yet seroconverted, or (iii) for treatment monitoring. PMID:21489253

  18. Determination of ideal-gas enthalpies of formation for key compounds: The 1989 project results

    NASA Astrophysics Data System (ADS)

    Steele, W. V.; Chirico, R. D.; Nguyen, A.; Hossenlopp, I. A.; Smith, N. K.

    1991-10-01

    The results of a study aimed at improvement of group-contribution methodology for estimation of thermodynamic properties of organic and organosilicon substances are reported. Specific weaknesses where particular group-contribution terms were unknown, or estimated because of lack of experimental data, are addressed by experimental studies of enthalpies of combustion in the condensed phase, vapor pressure measurements, and differential scanning calorimetric (dsc) heat capacity measurements. Ideal gas enthalpies of formation of (+ or -) butan-2-ol, tetradecan-1-ol, hexan-1,6-diol, methacrylamide, benzoyl formic acid, naphthalene 2,6-dicarboxylic acid dimethyl ester, and tetraethylsilane are reported. A crystalline-phase enthalpy of formation at 298.15 K was determined for naphthalene-2,6-dicarboxylic acid, which decomposed at 695 K before melting. The combustion calorimetry of tetraethylsilane used the proven fluorine-additivity methodology. Critical temperature and critical density were determined for tetraethylsilane with differential scanning calorimeter and the critical pressure was derived. Group additivity parameters useful in the application of group contribution correlations are derived.

  19. Alemtuzumab in the treatment of multiple sclerosis: key clinical trial results and considerations for use

    PubMed Central

    Horakova, Dana; Kovarova, Ivana

    2015-01-01

    Alemtuzumab is a humanized monoclonal antibody therapy that has recently been approved in over 30 countries for patients with active relapsing-remitting multiple sclerosis. It acts by targeting CD52, an antigen primarily expressed on T and B lymphocytes, resulting in their depletion and subsequent repopulation. The alemtuzumab clinical development program used an active comparator, subcutaneous interferon beta-1a, to show that alemtuzumab is a highly efficacious disease-modifying therapy, with benefits on relapses, disability outcomes, and freedom from clinical disease and magnetic resonance imaging activity. The safety profile was consistent across studies and no new safety signals have emerged during follow-up in the extension study. Infusion-associated reactions are common with alemtuzumab, but rarely serious. Infection incidence was elevated with alemtuzumab in clinical studies; most infections were mild or moderate in severity. Autoimmune adverse events occurred in approximately a third of patients, manifesting mainly as thyroid disorders, and less frequently as immune thrombocytopenia or nephropathy. A comprehensive monitoring program lasting at least 4 years after the last alemtuzumab dose allows early detection and effective management of autoimmune adverse events. Further experience with alemtuzumab in the clinic will provide needed long-term data. PMID:25584072

  20. Determining barriers to creating an enabling environment in Cambodia: results from a baseline study with key populations and police

    PubMed Central

    Schneiders, Mira L; Weissman, Amy

    2016-01-01

    Introduction Cambodian law enforcement's limited acceptance of harm reduction has hindered HIV program effectiveness. With funding from the Australian Department of Foreign Affairs and Trade, FHI 360 supported the Ministry of Interior to implement the Police Community Partnership Initiative (PCPI) in Cambodia's capital Phnom Penh. To guide this, FHI 360 conducted a baseline study examining police and key populations’ attitudes and practices towards one another, including fear and occurrence of arrest. Methods Between December 2012 and January 2013, a cross-sectional survey of 199 police post officers, 199 people who use drugs (PWUD) including people who inject drugs (PWID), 199 men who have sex with men (MSM), 200 transgender women (TGW) and 200 female entertainment workers (FEW) was conducted in five Phnom Penh districts. Eligible participants were ≥18 years, members of a key population from selected hotspots or police officers, deputy chiefs or chiefs. Results Key populations’ median age was 25 years (IQR: 22–30); 40% had completed only primary school. Police were male (99.5%), with median age 43 years (IQR: 30 to 47), and 45 and 25% high school and university completion rates, respectively. Key populations feared arrest for carrying needles and syringes (67%), condoms (23%) and 19% felt afraid to access health services. Close to 75% of police reported body searching and 58% arresting key populations in the past six months for using drugs (64%), selling or distributing drugs (36%) or being violent (13%). Self-reported arrests (23% PWUD, 6% MSM, 6% TGW, 12% FEW; p<0.05), being verbally threatened (45% PWUD, 21% MSM, 25% TGW, 27% FEW; p<0.001) and body searched (44% PWUD, 28% MSM, 23% TGW, 8% FEW; p<0.001) was significantly higher among PWUD than other key populations. The majority (94%) of police believed arrest was an appropriate solution to reduce HIV and drug use and reported selling sex (88%) and carrying needles and syringes (55%) as valid reasons for

  1. 76 FR 35405 - Solid Urea From the Russian Federation: Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... From the Union of Soviet Socialist Republics, 52 FR 26367 (July 14, 1987). Following the break-up of... Comment, 57 FR 28828 (June 29, 1992). Pursuant to section 751(a)(1) of the Tariff Act of 1930, as amended... Countervailing Duty Administrative Reviews and Deferral of Initiation of Administrative Review, 75 FR...

  2. 76 FR 23974 - Certain Pasta From Turkey: Notice of Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... Turkey, 61 FR 38545 (July 24, 1996) (Amended Final Determination). On July 1, 2010, we published in the... Administrative Review, 75 FR 38074 (July 1, 2010). On July 30, 2010, we received a request from petitioners to... Initiation of Administrative Review, 75 FR 53274 (August 31, 2010); see also Certain Pasta from...

  3. 75 FR 12199 - Stainless Steel Bar from India: Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... Administrative Review, 73 FR 45708, 45710 (August 6, 2008), unchanged in SSSS from Mexico and accompanying Issues...'') from India. See Antidumping Duty Orders: Stainless Steel Bar from Brazil, India and Japan, 60 FR 9661... Request Administrative Review, 74 FR 6013 (February 4, 2009). On February 19, 2009, the...

  4. 77 FR 46386 - Certain Pasta From Turkey: Preliminary Results of Countervailing Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ...; Opportunity To Request Administrative Review, 76 FR 38609 (July 1, 2011). \\2\\ See Letter from Marsan, Birlik... Administrative Reviews and Requests for Revocation in Part, 76 FR 53404 (August 26, 2011) (``Initiation Notice... pounds (or 2.27 kilograms) or less, whether or not enriched or fortified or containing milk or...

  5. Assessment for 1983-4 School Year. Administrative/Supervisory Performance Review Process. Survey Results.

    ERIC Educational Resources Information Center

    Gallagher, Michael P.

    School administrators and supervisors who were evaluated using the Cleveland, Ohio City School District's Administrator/Supervisory Review Process were surveyed concerning their opinions of the review process. The questionnaire, which was returned by 203 principals, assistant principals, and other supervisory staff out of a total of 376…

  6. 76 FR 2655 - Honey From Argentina: Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ...: Honey From Argentina, 66 FR 63672 (December 10, 2001). On December 1, 2009, the Department published in... Administrative Review, 74 FR 62743 (December 1, 2009). In response, on December 31, 2009, Asociacion de... Initiation of Administrative Review, 75 FR 4770, 4772 (January 29, 2010) (Initiation Notice). \\1\\...

  7. 76 FR 33210 - Preliminary Results of Antidumping Duty Administrative Review: Circular Welded Carbon Steel Pipes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... and Tubes From Taiwan: Antidumping Duty Order, 49 FR 19369 (May 7, 1984) (Antidumping Duty Order). On...; Opportunity To Request Administrative Review, 75 FR 23236, 23237 (May 3, 2010). On June 1, 2010, a domestic... Duty Administrative Reviews and Requests for Revocation in Part, 75 FR 37759 (June 30, 2010)....

  8. 78 FR 49256 - Certain Pasta From Italy: Preliminary Results of the Countervailing Duty Administrative Review; 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE... Commerce. SUMMARY: The Department of Commerce (``Department'') is conducting an administrative review of..., 2011, through December 31, 2011. We preliminarily determine that Molino e Pastificio Tomasello...

  9. Laser spark ignition of premixed methane-air mixtures: parameter measurements and determination of key factors for ultimate ignition results.

    PubMed

    Li, Xiaohui; Smith, Benjamin W; Omenetto, Nicoló

    2014-01-01

    In this study, we present an experimental investigation of the parameters of the laser spark ignition of premixed methane-air mixtures and the determination of the key factors for the ultimate ignition result. Ignition is achieved in a mesh honeycomb burner using the 1064 nm output of a neodymium-doped yttrium aluminum garnet (Nd : YAG) laser. All pertinent laser ignition parameters, including the minimum ignition energy, the ignition time and blow out time, and the effects that the variation of experimental conditions, such as the spark energy, ignition position, equivalence ratio (ER), and flow rate, have on these parameters have been addressed systematically. To identify the key factors for the ultimate result of laser ignition, several parameters of the ignition processes are measured simultaneously, with an emphasis given to the temporal behavior of the hydroxyl (OH) radicals in relation to the data regarding the spark energy and the local ER. A clear finding of the study is that successful ignition events are always related to higher OH radical photon emissions, considered to be proportional to the concentration level of the OH radicals present, thus indicating a direct link between the OH level at early times (on a microsecond scale) and the ultimate result of laser ignition. Two-dimensional correlation plots of the spark energy, local ER, and OH radical photon count at early times with the ultimate results of laser ignition indicate that the spark energy and local ER do not play a critical role in determining the success or failure of the ignition and that the OH concentration in the early time range is the key factor in determining the final fate of laser ignition. Finally, on the basis of the results obtained here and in the existing literature, some considerations of the mechanism of laser ignition are presented. PMID:25226251

  10. 75 FR 18794 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... Orange Juice from Brazil, 71 FR 12183 (Mar. 9, 2006) (OJ Order). Subsequently, on March 2, 2009, the...; Opportunity To Request Administrative Review, 74 FR 9077 (Mar. 2, 2009). In accordance with 19 CFR 351.213(b... Reviews and Request for Revocation in Part, 74 FR 19042 (Apr. 27, 2009). In May 2009, we...

  11. 76 FR 19315 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... certain orange juice from Brazil. See Antidumping Duty Order: Certain Orange Juice from Brazil, 71 FR... Administrative Review, 75 FR 9162 (Mar. 1, 2010). In accordance with 19 CFR 351.213(b)(2), in March 2010, the... Request for Revocation in Part, 75 FR 22107 (Apr. 27, 2010). Also in April 2010, we issued...

  12. 78 FR 41367 - Chlorinated Isocyanurates From Spain: Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... Countervailing Duty Administrative Reviews and Requests for Revocation in Part, 77 FR 45338 (July 31, 2012... of Antidumping Duties, 68 FR 23954 (May 6, 2003). Cash Deposit Requirements The following cash...: Notice of Final Determination of Sales at Less Than Fair Value, 70 FR 24506 (May 10, 2005)....

  13. 75 FR 19610 - Solid Urea From the Russian Federation: Preliminary Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... Soviet Socialist Republics, 52 FR 26367 (July 14, 1987). Following the break-up of the Soviet Union, the... of Independent States and the Baltic States and Opportunity to Comment, 57 FR 28828 (June 29, 1992..., 74 FR 42873 (August 25, 2009). We are conducting the administrative review of the order in...

  14. 78 FR 50376 - Polyethylene Retail Carrier Bags From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... at Less Than Fair Value: Polyethylene Retail Carrier Bags From Thailand, 69 FR 34122- 34124 (June 18... Review, 72 FR 1982, 1983 (January 17, 2007), Polyethylene Retail Carrier Bags from Thailand: Final... Administrative Review, 72 FR 64580 (November 16, 2007), Polyethylene Retail Carrier Bags from Thailand:...

  15. 75 FR 977 - Carbazole Violet Pigment 23 From India: Preliminary Results of Countervailing Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-07

    ... Affirmative Countervailing Duty Determination: Carbazole Violet Pigment 23 From India, 69 FR at 67321. These... Pigment 23 from India, 69 FR 77995 (December 29, 2004) (CVP-23 Order). On December 1, 2008, the Department... Request Administrative Review, 73 FR 72764 (December 1, 2008). On December 30, 2008, the...

  16. 75 FR 49907 - Certain Pasta From Italy: Notice of Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... Initiation FR of Antidumping and Countervailing Duty Administrative Reviews and Request for Revocation in Part, 74 FR 42873, 42875. The Department acknowledges that the correct spelling is ``Garofalo.'' DATES... Order and Amended Final Determination of Sales at Less Than Fair Value: Certain Pasta From Italy, 61...

  17. 78 FR 42492 - Certain Frozen Warmwater Shrimp From India: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... Exp. Pvt., Ltd 3.49 Shree Datt Aquaculture Farms Pvt. Ltd 3.49 Shroff Processed Food & Cold Storage P... Duty Administrative Review; 2011-2012, 78 FR 15691 (Mar. 12, 2013) and accompanying Decision Memorandum.../exporters. The respondents which the Department selected for individual examination are Apex Frozen...

  18. 78 FR 56860 - Honey From the People's Republic of China: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... and Partial Rescission of Antidumping Duty Administrative Review; 2011-2012, 78 FR 38941 (June 28... Antidumping Proceedings: Assessment of Antidumping Duties, 76 FR 65694 (October 24, 2011). \\6\\ See id. Cash... Global Logistics (Shanghai) Co. 10. Baiste Trading Co., Ltd. 11. Cheng Du Wai Yuan Bee Products Co.,...

  19. College and University Dining Services Administrators' Intention to Adopt Sustainable Practices: Results from US Institutions

    ERIC Educational Resources Information Center

    Chen, Chao-Jung; Gregoire, Mary B.; Arendt, Susan; Shelley, Mack C.

    2011-01-01

    Purpose: The purpose of this paper is to examine college and university dining services administrators' (CUDSAs) intention to adopt sustainable practices. Design/methodology/approach: The theory of planned behavior (TPB) including constructs of subjective norm (SN), attitude, perceived behavior control, and personal norm (PN), formed the…

  20. 75 FR 23674 - Honey from Argentina: Final Results of Antidumping Duty Administrative Review and Determination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... in the LTFV investigation. See Notice of Antidumping Duty Order; Honey From Argentina, 66 FR 63672... Duty Administrative Review and Intent to Revoke Order in Part, 74 FR 68570 (December 28, 2009..., 74 FR at 68572 and Memorandum to John M. Andersen, Acting Deputy Assistant Secretary for...

  1. 75 FR 12514 - Stainless Steel Bar From Brazil: Preliminary Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... Brazil. See Antidumping Duty Orders: Stainless Steel Bar from Brazil, India and Japan, 60 FR 9661... Steel Bar From Brazil, 59 FR 66914 (December 28, 1994). These deposit requirements, when imposed, shall..., Finding, or Suspended Investigation; Opportunity To Request Administrative Review, 74 FR 6013 (February...

  2. 77 FR 1458 - Honey From Argentina: Preliminary Results of Antidumping Duty Administrative Review and Partial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... FR 63672 (December 10, 2001). On December 1, 2010, the Department published in the Federal Register... FR 74682 (December 1, 2010). In response, the Department received the following requests for review... Order, Finding, or Suspended Investigation; Opportunity To Request Administrative Review, 75 FR at...

  3. 75 FR 32911 - Preliminary Results of Antidumping Duty Administrative Review: Circular Welded Carbon Steel Pipes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... and Tubes From Taiwan: Antidumping Duty Order, 49 FR 19369 (May 7, 1984) (Antidumping Duty Order). On...; Opportunity To Request Administrative Review, 74 FR 20278 (May 1, 2009). On June 1, 2009, a domestic producer... for Revocation in Part, 74 FR 30052 (June 24, 2009). Yieh Phui submitted a response to Section A...

  4. The Hubble Space Telescope quasar absorption line key project. III - First observational results on Milky Way gas

    NASA Technical Reports Server (NTRS)

    Savage, Blair D.; Lu, Limin; Bahcall, John N.; Bergeron, Jacqueline; Boksenberg, Alec; Hartig, George F.; Jannuzi, Buell T.; Kirhakos, Sofia; Lockman, Felix J.; Sargent, W. L. W.

    1993-01-01

    Absorption lines found near zero redshift due to Milky Way disk and halo gas in the spectra of 15 quasars observed with the Faint Object Spectrograph (FOS) of the HST at a resolution of about 230 km/s are reported. Results show that Milky Way absorption lines comprise about 44 percent of all absorption lines seen in the first group of Key Project FOS spectra. Milky Way lines were observed for 3C 273 and H1821 + 643. Limits to the Mg-to-H abundance ratio obtained for very high velocity Mg II absorption detections imply gas-phase Mg abundances for the very high velocity gas ranging from more than 0.059 to more than 0.32 times the solar abundance. In all cases where high-velocity H I emission is seen, corresponding high-velocity metal-line absorption is observed.

  5. 75 FR 37386 - Certain Pasta from Italy: Final Results of the 13th (2008) Countervailing Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... Administrative Review, 75 FR 18806 (April 13, 2010) (``Preliminary Results''). We did not receive any comments on... Initiation of Anti-Circumvention Inquiry on the Antidumping and Countervailing Duty Orders, 65 FR 26179 (May... Orders, 68 FR 54888 (September 19, 2003). Final Results of Review In accordance with 19 CFR...

  6. 76 FR 68399 - Certain Pasta From Turkey: Notice of Final Results of the 14th Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... of Preliminary Results of Antidumping Duty Administrative Review, 76 FR 23974 (April 29, 2011... the investigation of 51.49 percent. See Preliminary Results, 76 FR at 23977-78. \\2\\ See Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954, 23954 (May 6,...

  7. 77 FR 64100 - Glycine from the People's Republic of China: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... agent, reabsorbable amino acid, chemical intermediate, and a metal complexing agent. This review covers... Administrative Review, 77 FR 21738 (April 11, 2012) (Preliminary Results). \\2\\ See Memorandum to the File... a timely request to withdraw its request for review of these companies. Preliminary Results, 77...

  8. 76 FR 56401 - Stainless Steel Bar from India: Final Results of the Antidumping Duty Administrative Review, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... Order, in Part, 76 FR 12044 (March 4, 2011) (``Preliminary Results''). After publishing the Preliminary... Administrative Review, 76 FR 20950 (April 14, 2011). We invited parties to comment on the Preliminary Results. On...: Stainless Steel Bar from India, 59 FR 66915 (December 28, 1994). These cash deposit requirements,...

  9. A key role for the N/OFQ-NOP receptor system in modulating nicotine taking in a model of nicotine and alcohol co-administration

    PubMed Central

    Cippitelli, Andrea; Schoch, Jennifer; Debevec, Ginamarie; Brunori, Gloria; Zaveri, Nurulain T.; Toll, Lawrence

    2016-01-01

    Alcohol and nicotine are often co-abused. Although the N/OFQ-NOP receptor system is considered a potential target for development of drug abuse pharmacotherapies, especially for alcoholism, little is known about the role of this system in nicotine dependence. Furthermore, the effect of prior history of nicotine dependence on subsequent nicotine and alcohol taking is understudied. Using an operant co-administration paradigm, in which rats concurrently self-administer nicotine and alcohol, we found that nicotine dependent rats increased nicotine self-administration over time as compared to non-dependent animals, while patterns of alcohol lever pressing did not change between groups. Pretreatment with the potent NOP receptor agonist AT-202 (0.3–3 mg/kg) increased nicotine lever pressing of both dependent and non-dependent groups, whereas the selective antagonist SB612111 (1–10 mg/kg) elicited a clear reduction of nicotine responses, in both dependent and non-dependent rats. In parallel, AT-202 only produced minor changes on alcohol responses and SB612111 reduced alcohol taking at a dose that also reduced locomotor behavior. Results indicate that a history of nicotine dependence affects subsequent nicotine- but not alcohol-maintained responding, and that NOP receptor antagonism, rather than agonism, blocks nicotine self-administration, which strongly suggests a critical role for the endogenous N/OFQ in the modulation of nicotine reinforcement processes. PMID:27199205

  10. Educational Consequences of Developmental Speech Disorder: Key Stage 1 National Curriculum Assessment Results in English and Mathematics

    ERIC Educational Resources Information Center

    Nathan, L.; Stackhouse, J.; Goulandris, N.; Snowling, M.J.

    2004-01-01

    Background: Children with speech difficulties may have associated educational problems. This paper reports a study examining the educational attainment of children at Key Stage 1 of the National Curriculum who had previously been identified with a speech difficulty. Aims: (1) To examine the educational attainment at Key Stage 1 of children…

  11. Colorectal Cancer Screening Programme in Spain: Results of Key Performance Indicators After Five Rounds (2000-2012).

    PubMed

    Binefa, Gemma; Garcia, Montse; Milà, Núria; Fernández, Esteve; Rodríguez-Moranta, Francisco; Gonzalo, Núria; Benito, Llúcia; Clopés, Ana; Guardiola, Jordi; Moreno, Víctor

    2016-01-20

    Effective quality assurance is essential in any screening programme. This article provides a unique insight into key quality indicators of five rounds of the first population-based colorectal cancer screening programme implemented in Spain (2000-2012), providing the results according to the type of screening (prevalent or first screen and incident or subsequent screen) and test (guaiac or immunochemical). The total crude participation rate increased from 17.2% (11,011) in the first round to 35.9% (22,988) in the last one. Rescreening rate was very high (88.6% in the fifth round). Positivity rate was superior with the faecal immunochemical test (6.2%) than with the guaiac-based test (0.7%) (p < 0.0001) and detection rates were also better with the immunochemical test. The most significant rise in detection rate was observed for high risk adenoma in men (45.5 per 1,000 screened). Most cancers were diagnosed at an early stage (61.4%) and there was a statistically significant difference between those detected in first or subsequent screening (52.6% and 70.0% respectively; p = 0.024). The availability of these results substantially improves data comparisons and the exchange of experience between screening programmes.

  12. 78 FR 9364 - Certain Pasta From Italy: Notice of Final Results of 15th Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... Preliminary Results of Antidumping Duty Administrative Review, 77 FR 46377 (August 3, 2012) (Preliminary..., 73 FR 33,977 (June 16, 2008) (Steel Nails), and accompanying Issues and Decision Memorandum at... Less Than Fair Value, 76 FR 64318 (October 18, 2011) (Wood Flooring), and accompanying Issues...

  13. 78 FR 34337 - Stainless Steel Bar From India: Final Results of Antidumping Duty Administrative Review; 2011-2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ... from India: Preliminary Results of the Antidumping Duty Administrative Review, 78 FR 7395 (February 1... Less Than Fair Value: Stainless Steel Bar from India, 59 FR 66915 (December 28, 1994). Notifications... Proceedings; Final Modification, 77 FR 8101 (February 14, 2012) (Final Modification). The Department...

  14. 78 FR 37794 - Polyvinyl Alcohol from Taiwan: Final Results of Antidumping Duty Administrative Review; 2010-2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... commercial levels of defoamer or boric acid. PVA in fiber form and PVB-grade low-ash PVA are not included in... Administrative Review, 78 FR 20890 (April 8, 2013) (Preliminary Results) and the accompanying Preliminary... Dumping Margin and Assessment Rate in Certain Antidumping Duty Proceedings; Final Modification, 77 FR...

  15. 75 FR 24880 - Administrative Review of Honey from the People's Republic of China: Final Results of Antidumping...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... Review and Intent to Rescind, In Part, 74 FR 68249 (December 23, 2009) (``Preliminary Results''). DATES... and Countervailing Duty Administrative Reviews and Request for Revocation in Part, 74 FR 5821... Review, 74 FR 11087 (March 16, 2009). As noted above, on December 23, 2009, the Department published...

  16. 78 FR 9672 - Certain Pasta From Turkey; 2010-2011; Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... Preliminary Results of the 2010-2011 Antidumping Duty Administrative Review, 77 FR 46694 (August 6, 2012... Margin and Assessment Rate in Certain Antidumping Proceedings: Final Modification, 77 FR 8101 (February... Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6,...

  17. 78 FR 22227 - Stainless Steel Bar From Brazil: Final Results of Antidumping Duty Administrative Review; 2011-2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ...: Stainless Steel Bar from Brazil, India and Japan, 60 FR 9661 (February 21, 1995). Changes Since the... Bar From Brazil, 59 FR 66914 (December 28, 1994). These cash deposit requirements shall remain in... Administrative Review; 2011-2012, 78 FR 4383 (January 22, 2013) (Preliminary Results). We invited...

  18. Positive and negative placebo effects resulting from the deceptive administration of an ergogenic aid.

    PubMed

    Beedie, Christopher J; Coleman, Damian A; Foad, Abigail J

    2007-06-01

    The article describes a study examining placebo effects associated with the administration of a hypothetical ergogenic aid in sport. Forty-two team-sport athletes were randomly assigned to 2 groups. All subjects completed 3 x 30-m baseline sprint trials after which they were administered what was described to them as an ergogenic aid but was in fact 200 mg of cornstarch in a gelatin capsule. Group 1 was provided with positive information about the likely effects on performance of the substance, whereas Group 2 was provided with negative information about the same substance. The sprint protocol was repeated 20 min later. Although for Group 1 mean speed did not differ significantly between baseline and experimental trials, a significant linear trend of greater speed with successive experimental trials suggested that positive belief exerted a positive effect on performance (P < 0.01). Group 2 ran 1.57% slower than at baseline (P < 0.01, 95% confidence intervals 0.32-2.82%), suggesting that negative belief exerted a negative effect on performance. Collectively, data suggest that subjects' belief in the efficacy or otherwise of a placebo treatment might significantly influence findings in experimental research. PMID:17693687

  19. Results from the Veterans Health Administration ICD-10-CM/PCS Coding Pilot Study.

    PubMed

    Weems, Shelley; Heller, Pamela; Fenton, Susan H

    2015-01-01

    The Veterans Health Administration (VHA) of the US Department of Veterans Affairs has been preparing for the October 1, 2015, conversion to the International Classification of Diseases, Tenth Revision, Clinical Modification and Procedural Coding System (ICD-10-CM/PCS) for more than four years. The VHA's Office of Informatics and Analytics ICD-10 Program Management Office established an ICD-10 Learning Lab to explore expected operational challenges. This study was conducted to determine the effects of the classification system conversion on coding productivity. ICD codes are integral to VHA business processes and are used for purposes such as clinical studies, performance measurement, workload capture, cost determination, Veterans Equitable Resource Allocation (VERA) determination, morbidity and mortality classification, indexing of hospital records by disease and operations, data storage and retrieval, research purposes, and reimbursement. The data collection for this study occurred in multiple VHA sites across several months using standardized methods. It is commonly accepted that coding productivity will decrease with the implementation of ICD-10-CM/PCS. The findings of this study suggest that the decrease will be more significant for inpatient coding productivity (64.5 percent productivity decrease) than for ambulatory care coding productivity (6.7 percent productivity decrease). This study reveals the following important points regarding ICD-10-CM/PCS coding productivity: 1. Ambulatory care ICD-10-CM coding productivity is not expected to decrease as significantly as inpatient ICD-10-CM/PCS coding productivity. 2. Coder training and type of record (inpatient versus outpatient) affect coding productivity. 3. Inpatient coding productivity is decreased when a procedure requiring ICD-10-PCS coding is present. It is highly recommended that organizations perform their own analyses to determine the effects of ICD-10-CM/PCS implementation on coding productivity.

  20. Results from the Veterans Health Administration ICD-10-CM/PCS Coding Pilot Study.

    PubMed

    Weems, Shelley; Heller, Pamela; Fenton, Susan H

    2015-01-01

    The Veterans Health Administration (VHA) of the US Department of Veterans Affairs has been preparing for the October 1, 2015, conversion to the International Classification of Diseases, Tenth Revision, Clinical Modification and Procedural Coding System (ICD-10-CM/PCS) for more than four years. The VHA's Office of Informatics and Analytics ICD-10 Program Management Office established an ICD-10 Learning Lab to explore expected operational challenges. This study was conducted to determine the effects of the classification system conversion on coding productivity. ICD codes are integral to VHA business processes and are used for purposes such as clinical studies, performance measurement, workload capture, cost determination, Veterans Equitable Resource Allocation (VERA) determination, morbidity and mortality classification, indexing of hospital records by disease and operations, data storage and retrieval, research purposes, and reimbursement. The data collection for this study occurred in multiple VHA sites across several months using standardized methods. It is commonly accepted that coding productivity will decrease with the implementation of ICD-10-CM/PCS. The findings of this study suggest that the decrease will be more significant for inpatient coding productivity (64.5 percent productivity decrease) than for ambulatory care coding productivity (6.7 percent productivity decrease). This study reveals the following important points regarding ICD-10-CM/PCS coding productivity: 1. Ambulatory care ICD-10-CM coding productivity is not expected to decrease as significantly as inpatient ICD-10-CM/PCS coding productivity. 2. Coder training and type of record (inpatient versus outpatient) affect coding productivity. 3. Inpatient coding productivity is decreased when a procedure requiring ICD-10-PCS coding is present. It is highly recommended that organizations perform their own analyses to determine the effects of ICD-10-CM/PCS implementation on coding productivity. PMID

  1. Results from the Veterans Health Administration ICD-10-CM/PCS Coding Pilot Study

    PubMed Central

    Weems, Shelley; Heller, Pamela; Fenton, Susan H.

    2015-01-01

    The Veterans Health Administration (VHA) of the US Department of Veterans Affairs has been preparing for the October 1, 2015, conversion to the International Classification of Diseases, Tenth Revision, Clinical Modification and Procedural Coding System (ICD-10-CM/PCS) for more than four years. The VHA's Office of Informatics and Analytics ICD-10 Program Management Office established an ICD-10 Learning Lab to explore expected operational challenges. This study was conducted to determine the effects of the classification system conversion on coding productivity. ICD codes are integral to VHA business processes and are used for purposes such as clinical studies, performance measurement, workload capture, cost determination, Veterans Equitable Resource Allocation (VERA) determination, morbidity and mortality classification, indexing of hospital records by disease and operations, data storage and retrieval, research purposes, and reimbursement. The data collection for this study occurred in multiple VHA sites across several months using standardized methods. It is commonly accepted that coding productivity will decrease with the implementation of ICD-10-CM/PCS. The findings of this study suggest that the decrease will be more significant for inpatient coding productivity (64.5 percent productivity decrease) than for ambulatory care coding productivity (6.7 percent productivity decrease). This study reveals the following important points regarding ICD-10-CM/PCS coding productivity: Ambulatory care ICD-10-CM coding productivity is not expected to decrease as significantly as inpatient ICD-10-CM/PCS coding productivity.Coder training and type of record (inpatient versus outpatient) affect coding productivity.Inpatient coding productivity is decreased when a procedure requiring ICD-10-PCS coding is present. It is highly recommended that organizations perform their own analyses to determine the effects of ICD-10-CM/PCS implementation on coding productivity. PMID:26396553

  2. 75 FR 41813 - Certain Frozen Warmwater Shrimp From India: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Order in Part, 75 FR 12175 (Mar. 15, 2010) (Preliminary Results). We invited parties to comment on the..., but are not limited to, whiteleg shrimp (Penaeus vannemei), banana prawn (Penaeus merguiensis), fleshy... once). See Preliminary Results, 75 FR at 12178-12179. Since the Preliminary Results we have received...

  3. The 'Vertical Structure and Diabatic Processes of the Madden-Julian Oscillation' model evaluation project: Overview and key results (Invited)

    NASA Astrophysics Data System (ADS)

    Klingaman, N. P.; Jiang, X.; Xavier, P.; Petch, J.; Waliser, D. E.; Woolnough, S.

    2013-12-01

    -level temperature and humidity, evaluated against YoTC analyses, within 48 hours. These biases stem from large differences in cloud cover above the freezing level in models, which lead to discrepancies in the magnitude and even sign of the radiative temperature increments; this points to errors in cloud-radiative interactions in these models. In the 20-day hindcasts, there is no relationship between a model's ability to predict the MJO and its vertical profile of diabatic heating; models with similar diabatic-heating profiles have very different levels of skill in these hindcasts. A more consistent association is found between MJO skill and diabatic-moistening profiles, with high-skill models showing a clear transition from shallow moistening in suppressed conditions to deep moistening during the active phase. We will present an overview of the evaluation project, its goals and objectives; highlight key results from each components of the project; and discuss the next steps for further analysis, including the dissemination of data to the wider community.

  4. 78 FR 20891 - Glycine From the People's Republic of China: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ... Chemistry Co. Ltd. (Baoding Mantong), and are rescinding the review with respect to companies for which this..., 77 FR 72817 (December 6, 2012) (Preliminary Results), and accompanying Decision Memorandum for the... companies. See Preliminary Results, 77 FR at 72817. FOR FURTHER INFORMATION CONTACT: Brian Davis or...

  5. 76 FR 59999 - Polyethylene Retail Carrier Bags From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Corporation (collectively, the petitioners), and the respondents, Thai Plastic Bags Industries Co., Ltd. (TPBI... ``Polyethylene Retail Carrier Bags from Thailand-- Thai Plastic Bags Industries Co., Ltd. (TPBI), Final Results... Adjustments for the Final Results--Thai Plastic Bags Industries Co. (TPBI), Ltd.'' dated September 21,...

  6. 78 FR 42497 - Certain Frozen Warmwater Shrimp From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ...-2012, 78 FR 15686 (Mar. 12, 2013) (Preliminary Results), and accompanying Preliminary Decision... for Revocation of Order in Part, 77 FR 19612 (Apr. 2, 2012) (Initiation Notice). (1) Anglo-Siam... Union Manufacturing Company Limited (11) V. Thai Food Product Co., Ltd. See Preliminary Results, 78...

  7. Impact of Low Procalcitonin Results on Antibiotic Administration in Hospitalized Patients at a Tertiary Care Center.

    PubMed

    Brennan, Meghan B; Osterby, Kurt; Schulz, Lucas; Lepak, Alexander J

    2016-06-01

    Procalcitonin is a sensitive and specific marker of bacterial infection; low results allow clinicians to safely de-escalate antibiotics. This retrospective cohort study aimed to determine the effect of low procalcitonin results on withholding, discontinuing, or de-escalating antibiotics in hospitalized patients at a tertiary care center. Antibiotics were initiated or continued without de-escalation in 55% of patients with low procalcitonin results. Among patients with low procalcitonin results, the primary service, but not measures of patient complexity, disease severity, or underlying disease process (lower respiratory tract infection evaluation versus systemic inflammatory response syndrome/possible sepsis) was associated with initiation or continued broad-spectrum antibiotic use. Provider-level factors may be an important variable in the initiation or continued use of broad-spectrum antibiotics for patients with low procalcitonin levels. PMID:27251126

  8. Constructing a Cross-Domain Resource Inventory: Key Components and Results of the EarthCube CINERGI Project.

    NASA Astrophysics Data System (ADS)

    Zaslavsky, I.; Richard, S. M.; Malik, T.; Hsu, L.; Gupta, A.; Grethe, J. S.; Valentine, D. W., Jr.; Lehnert, K. A.; Bermudez, L. E.; Ozyurt, I. B.; Whitenack, T.; Schachne, A.; Giliarini, A.

    2015-12-01

    While many geoscience-related repositories and data discovery portals exist, finding information about available resources remains a pervasive problem, especially when searching across multiple domains and catalogs. Inconsistent and incomplete metadata descriptions, disparate access protocols and semantic differences across domains, and troves of unstructured or poorly structured information which is hard to discover and use are major hindrances toward discovery, while metadata compilation and curation remain manual and time-consuming. We report on methodology, main results and lessons learned from an ongoing effort to develop a geoscience-wide catalog of information resources, with consistent metadata descriptions, traceable provenance, and automated metadata enhancement. Developing such a catalog is the central goal of CINERGI (Community Inventory of EarthCube Resources for Geoscience Interoperability), an EarthCube building block project (earthcube.org/group/cinergi). The key novel technical contributions of the projects include: a) development of a metadata enhancement pipeline and a set of document enhancers to automatically improve various aspects of metadata descriptions, including keyword assignment and definition of spatial extents; b) Community Resource Viewers: online applications for crowdsourcing community resource registry development, curation and search, and channeling metadata to the unified CINERGI inventory, c) metadata provenance, validation and annotation services, d) user interfaces for advanced resource discovery; and e) geoscience-wide ontology and machine learning to support automated semantic tagging and faceted search across domains. We demonstrate these CINERGI components in three types of user scenarios: (1) improving existing metadata descriptions maintained by government and academic data facilities, (2) supporting work of several EarthCube Research Coordination Network projects in assembling information resources for their domains

  9. Expression profile of key immune-related genes in Penaeus monodon juveniles after oral administration of recombinant envelope protein VP28 of white spot syndrome virus.

    PubMed

    Thomas, Ancy; Sudheer, Naduvilamuriparampu Saidumuhammed; Kiron, Viswanath; Bright Singh, Issac S; Narayanan, Rangarajan Badri

    2016-07-01

    White spot syndrome virus (WSSV) is the most catastrophic pathogen the shrimp industry has ever encountered. VP28, the abundant envelope protein of WSSV was expressed in bacteria, the purified protein administered orally to Penaeus monodon juveniles and its immune modulatory effects examined. The results indicated significant up-regulation of caspase, penaeidin, crustin, astakine, syntenin, PmRACK, Rab7, STAT and C-type lectin in animals orally administered with this antigen. This revealed the immune modulations in shrimps followed by oral administration of rVP28P which resulted in the reduced transcription of viral gene vp28 and delay in mortality after WSSV challenge. The study suggests the potential of rVP28P to elicit a non-specific immune stimulation in shrimps.

  10. [Results of talc administration using thoracoscopy in neoplastic pleurisies. Apropos of 218 cases].

    PubMed

    Ladjimi, S; M'Raihi, L; Djemel, A; Mathlouthi, A; Ben Ayed, F; Zegaya, M

    1989-01-01

    The authors report the results of their experience using tale pleurodesis under thoracoscopic control in the treatment of 218 cases of malignant pleural involvement. Although this technique is well tolerated it is necessary to note certain factors which prevent a successful pleurodesis (12% of cases). Thus, huge effusions greater than 12 litres, pleural involvement with large tumour masses, a very long history and patients aged more than 70 years were all factors contributing to a poor outcome. The success of pleural talc also depends on the nature of the primary cancer, for example in our series broncho-pulmonary cancers yielded better results than those effusions which were secondary to ovarian cancers.

  11. 76 FR 12700 - Polyethylene Retail Carrier Bags From Thailand: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    .... (Giant), Sahachit Watana Plastics Ind. Co., Ltd. (Sahachit Watana), Thai Plastic Bags Industries Co., Ltd... that TPBI, Apec Film Ltd., and Winner's Pack Co., Ltd., comprise the Thai Plastic Bags Group. See...--Thai Plastic Bags Industries Co., Ltd., Final Results Analysis Memorandum'' dated concurrently...

  12. 77 FR 40848 - Certain Frozen Warmwater Shrimp From India: Final Results of Antidumping Duty Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... Shipment Determination, 77 FR 13275 (Mar. 6, 2012) (Preliminary Results). Also in March 2012, the... (Penaeus vannemei), banana prawn (Penaeus merguiensis), fleshy prawn (Penaeus chinensis), giant river prawn... FR 18157 (Apr. 1, 2011) (Initiation Notice). We were unable to confirm the statements from two...

  13. HINDBRAIN AND CRANIAL NERVE DYSMORPHOGENESIS RESULT FROM ACUTE MATERNAL ETHANOL ADMINISTRATION

    EPA Science Inventory

    Acute exposure of mouse embryos to ethanol during stages of hindbrain segmentation results in excessive cell death in specific cell populations. This study details the ethanol-induced cell loss and defines the subsequent effects of this early insult on rhombomere and cranial ner...

  14. Repeated cocaine administration results in supersensitivity of striatal D-2 dopamine autoreceptors to pergolide

    SciTech Connect

    Dwoskin, L.P.; Peris, J.; Yasuda, R.P.; Philpott, K.; Zahniser, N.R.

    1988-01-01

    Groups of rats administered cocaine-HCl (10 mg/kg, i.p.) or saline either acutely or once daily for 8 or 14 days were killed 24 hrs after the last dose. In striatal slices prelabelled with (/sup 3/H)DA, modulation of (/sup 3/H)-overflow by pergolide was used to measure D-2 autoreceptor activity. Compared to the contemporaneous control group pergolide produced a greater inhibition only in striatal slices from rats treated repeatedly with cocaine. In radioligand binding studies using striatal membranes from control rats, pergolide had a 500-fold greater affinity for the D-2, as opposed to the D-1, dopamine (DA) receptor subtype. These results indicate that repeated treatment with cocaine produces supersensitive striatal D-2 release-modulating autoreceptors consistent with a compensatory change to diminish the effect of elevated synaptic concentrations of DA produced by cocaine. In contrast, supersensitivity of D-2 receptors was not detected in (/sup 3/H)spiperone binding assays. 31 references, 2 figures, 1 table.

  15. Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy.

    PubMed

    Dos Santos, Jair Guilherme; Longo, Beatriz Monteiro; Blanco, Mirian Marcela; Menezes de Oliveira, Maria Gabriela; Mello, Luíz Eugênio

    2005-12-20

    Cycloheximide influences synaptic reorganization resulting from pilocarpine-induced status epilepticus (SE). To investigate the possible behavioral consequences of this effect, we subjected animals to pilocarpine-induced SE either in the absence (Pilo group) or presence of cycloheximide (Chx group). Animals were further divided regarding the occurrence of spontaneous recurrent seizures (SRS). Two months after SE induction animals were exposed to different behavioral tests. Age-matched naïve animals were used as controls. All epileptic groups showed a significantly diminished freezing time in contextual and tone fear conditioning, performed poorly in the Morris water maze and present less seconds in immobility position as compared to controls. Only Pilo animals explored more extensively the open arms of the elevated plus maze and showed increased in horizontal exploratory activity in the open field as compared to controls. With the exception of Pilo animals without recorded SRS, all other groups had extensive tissue shrinkage in central nucleus of the amygdala as compared to controls. Cycloheximide-treated animals differed from Pilo animals in the extent of hilar loss and supragranular mossy fiber sprouting as well as tissue shrinkage in the dorsal hippocampus. Despite the histological differences seen in the dorsal hippocampus between experimental groups, no differences were encountered in the cognitive tests used to evaluate dorsal hippocampal function. The encountered histological differences between Chx and Pilo animals, however, might underlie the different emotional responses between the two groups.

  16. O+OH-->O(2)+H: A key reaction for interstellar chemistry. New theoretical results and comparison with experiment.

    PubMed

    Lique, F; Jorfi, M; Honvault, P; Halvick, P; Lin, S Y; Guo, H; Xie, D Q; Dagdigian, P J; Kłos, J; Alexander, M H

    2009-12-14

    We report extensive, fully quantum, time-independent (TID) calculations of cross sections at low collision energies and rate constants at low temperatures for the O+OH reaction, of key importance in the production of molecular oxygen in cold, dark, interstellar clouds and in the chemistry of the Earth's atmosphere. Our calculations are compared with TID calculations within the J-shifting approximation, with wave-packet calculations, and with quasiclassical trajectory calculations. The fully quantum TID calculations yield rate constants higher than those from the more approximate methods and are qualitatively consistent with a low-temperature extrapolation of earlier experimental values but not with the most recent experiments at the lowest temperatures.

  17. Supporting Innovations in Education: Preparing Administrators, Supervisors and Other Key Personnel. Report of a Technical Working Group Meeting (Seoul, South Korea, September 29-October 11, 1980).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

    Eleven countries (Bangladesh, India, Indonesia, Japan, Malaysia, Nepal, Pakistan, Philippines, South Korea, Sri Lanka, and Thailand) participated in a 1980 meeting on methods of training educational administrators and supervisors to be supportive of educational innovation. This report summarizes the proceedings of that meeting and the…

  18. Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology.

    PubMed

    Gadad, Bharathi S; Li, Wenhao; Yazdani, Umar; Grady, Stephen; Johnson, Trevor; Hammond, Jacob; Gunn, Howard; Curtis, Britni; English, Chris; Yutuc, Vernon; Ferrier, Clayton; Sackett, Gene P; Marti, C Nathan; Young, Keith; Hewitson, Laura; German, Dwight C

    2015-10-01

    Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Some anecdotal reports suggest that ASD is related to exposure to ethyl mercury, in the form of the vaccine preservative, thimerosal, and/or receiving the measles, mumps, rubella (MMR) vaccine. Using infant rhesus macaques receiving thimerosal-containing vaccines (TCVs) following the recommended pediatric vaccine schedules from the 1990s and 2008, we examined behavior, and neuropathology in three brain regions found to exhibit neuropathology in postmortem ASD brains. No neuronal cellular or protein changes in the cerebellum, hippocampus, or amygdala were observed in animals following the 1990s or 2008 vaccine schedules. Analysis of social behavior in juvenile animals indicated that there were no significant differences in negative behaviors between animals in the control and experimental groups. These data indicate that administration of TCVs and/or the MMR vaccine to rhesus macaques does not result in neuropathological abnormalities, or aberrant behaviors, like those observed in ASD. PMID:26417083

  19. Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology

    PubMed Central

    Gadad, Bharathi S.; Li, Wenhao; Yazdani, Umar; Grady, Stephen; Johnson, Trevor; Hammond, Jacob; Gunn, Howard; Curtis, Britni; English, Chris; Yutuc, Vernon; Ferrier, Clayton; Sackett, Gene P.; Marti, C. Nathan; Young, Keith; Hewitson, Laura; German, Dwight C.

    2015-01-01

    Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Some anecdotal reports suggest that ASD is related to exposure to ethyl mercury, in the form of the vaccine preservative, thimerosal, and/or receiving the measles, mumps, rubella (MMR) vaccine. Using infant rhesus macaques receiving thimerosal-containing vaccines (TCVs) following the recommended pediatric vaccine schedules from the 1990s and 2008, we examined behavior, and neuropathology in three brain regions found to exhibit neuropathology in postmortem ASD brains. No neuronal cellular or protein changes in the cerebellum, hippocampus, or amygdala were observed in animals following the 1990s or 2008 vaccine schedules. Analysis of social behavior in juvenile animals indicated that there were no significant differences in negative behaviors between animals in the control and experimental groups. These data indicate that administration of TCVs and/or the MMR vaccine to rhesus macaques does not result in neuropathological abnormalities, or aberrant behaviors, like those observed in ASD. PMID:26417083

  20. Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology.

    PubMed

    Gadad, Bharathi S; Li, Wenhao; Yazdani, Umar; Grady, Stephen; Johnson, Trevor; Hammond, Jacob; Gunn, Howard; Curtis, Britni; English, Chris; Yutuc, Vernon; Ferrier, Clayton; Sackett, Gene P; Marti, C Nathan; Young, Keith; Hewitson, Laura; German, Dwight C

    2015-10-01

    Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Some anecdotal reports suggest that ASD is related to exposure to ethyl mercury, in the form of the vaccine preservative, thimerosal, and/or receiving the measles, mumps, rubella (MMR) vaccine. Using infant rhesus macaques receiving thimerosal-containing vaccines (TCVs) following the recommended pediatric vaccine schedules from the 1990s and 2008, we examined behavior, and neuropathology in three brain regions found to exhibit neuropathology in postmortem ASD brains. No neuronal cellular or protein changes in the cerebellum, hippocampus, or amygdala were observed in animals following the 1990s or 2008 vaccine schedules. Analysis of social behavior in juvenile animals indicated that there were no significant differences in negative behaviors between animals in the control and experimental groups. These data indicate that administration of TCVs and/or the MMR vaccine to rhesus macaques does not result in neuropathological abnormalities, or aberrant behaviors, like those observed in ASD.

  1. KEY COMPARISON: Final report on CCEM key comparison CCEM.RF-K10.CL (GT-RF/99-2) 'Power in 50 Ω coaxial lines, frequency: 50 MHz to 26 GHz' measurement techniques and results

    NASA Astrophysics Data System (ADS)

    Janik, Dieter; Inoue, T.; Michaud, A.

    2006-01-01

    This report summarizes the results and the measuring methods of an international key comparison between twelve national metrology institutes (NMIs) and is concerning the calibration factor of RF power sensors in the coaxial 3.5 mm line for frequencies up to 26 GHz. Two RF power travelling standards fitted with male PC 3.5 mm connectors were measured at seven frequencies. The following NMIs participated: NMIJ (Japan), NRC (Canada), NIST (USA), METAS (Switzerland), CSIR-NML (South Africa), NMIA (Australia), NPL (UK), SiQ (Slovenia), IEN (Italy), VNIIFTRI (Russian Federation), SPRING (Singapore) and PTB (Germany), as the pilot laboratory. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  2. Monitoring the Future: National Results on Adolescent Drug Use. Overview of Key Findings 2005. NIH Publication No. 06-5882

    ERIC Educational Resources Information Center

    Johnson, Lloyd D.; O'Malley, Patrick M.; Bachman, Jerald G.; Schulenberg, John E.

    2006-01-01

    Results from the Monitoring the Future's 2005 nationwide survey of 8th, 10th, and 12th grade students are given in this report. Recent trends in the use of licit and illicit drugs are emphasized, as well as trends in the levels of perceived risk and personal disapproval associated with each drug. This study has shown these beliefs and attitudes to…

  3. Dopamine dynamics associated with, and resulting from, schedule-induced alcohol self-administration: Analyses in dopamine transporter knockout mice

    PubMed Central

    Mittleman, Guy; Call, Stanford B.; Cockroft, Jody L.; Goldowitz, Dan; Matthews, Douglas B.; Blaha, Charles D.

    2011-01-01

    Preclinical and clinical evidence suggest an association between alcoholism and the primary regulator of extracellular dopamine concentrations, the dopamine transporter (DAT). However, the nature of this association is unclear. We determined if ten days of voluntary alcohol self-administration followed by withdrawal could directly alter DAT function, or if genetically-mediated changes in DAT function and/or availability could influence vulnerability to alcohol abuse. Heterozygous (DAT+/-) and homozygous mutant (DAT-/-) and wildtype (DAT+/+) mice were allowed to consume 5% alcohol in a schedule-induced polydipsia (SIP) task. In vivo fixed potential amperometry in anesthetized mice was used to (1) identify functional characteristics of mesoaccumbens dopamine neurons related to genotype, including dopamine autoreceptor (DAR) sensitivity, DAT efficiency, and DAT capacity, (2) determine if any of these characteristics correlated with alcohol drinking observed in DAT+/+ and DAT+/- animals, and (3) determine if SIP-alcohol self-administration altered DAR sensitivity, DAT efficiency, and DAT capacity by comparing these characteristics in wildtype (DAT+/+) mice that were SIP-alcohol naïve, with those that had undergone SIP-alcohol testing. DAT-/- mice consumed significantly less alcohol during testing and this behavioral difference was related to significant differences in DAR sensitivity, DAT efficiency, and DAT capacity. These functional characteristics were correlated to varying degrees with g/kg alcohol consumption in DAT+/+ and DAT+/- mice. DAR sensitivity was consistently reduced and DAT efficiency was enhanced in SIP-alcohol experienced DAT+/+ mice in comparison to naïve animals. These results indicate that DAR sensitivity is reduced by SIP-alcohol consumption and that DAT efficiency is modified by genotype as well as SIP-alcohol exposure. DAT capacity appeared to be strictly associated with SIP-alcohol consumption. PMID:21354763

  4. Power Beamed Photon Sails: New Capabilities Resulting From Recent Maturation Of Key Solar Sail And High Power Laser Technologies

    NASA Astrophysics Data System (ADS)

    Montgomery, Edward E.

    2010-05-01

    This paper revisits some content in the First International Symposium on Beamed Energy Propulsion in 2002 related to the concept of propellantless in-space propulsion utilizing an external high energy laser to provide momentum to an ultralightweight (gossamer) spacecraft. The design and construction of the NanoSail-D solar sail demonstration spacecraft has demonstrated in space flight hardware the concept of small, very light—yet capable—spacecraft. The results of the Joint High Power Solid State Laser (JHPSSL) have also increased the effectiveness and reduced the cost of an entry level laser source. This paper identifies the impact from improved system parameters on current mission applications.

  5. Power Beamed Photon Sails: New Capabilities Resulting From Recent Maturation Of Key Solar Sail And High Power Laser Technologies

    SciTech Connect

    Montgomery, Edward E. IV

    2010-05-06

    This paper revisits some content in the First International Symposium on Beamed Energy Propulsion in 2002 related to the concept of propellantless in-space propulsion utilizing an external high energy laser to provide momentum to an ultralightweight (gossamer) spacecraft. The design and construction of the NanoSail-D solar sail demonstration spacecraft has demonstrated in space flight hardware the concept of small, very light--yet capable--spacecraft. The results of the Joint High Power Solid State Laser (JHPSSL) have also increased the effectiveness and reduced the cost of an entry level laser source. This paper identifies the impact from improved system parameters on current mission applications.

  6. DIPPER project 871 determination of ideal-gas enthalpies of formation for key compounds, The 1991 project results

    SciTech Connect

    Steele, W.V.; Chirico, R.D.; Knipmeyer, S.E.; Nguyen, A.; Tasker, I.R.

    1993-09-01

    Results of a study aimed at improving group-contribution methodology for estimating thermodynamic properties of organic substances are reported. Specific weaknesses where particular group-contribution terms were unknown, or estimated because of lack of experimental data, are addressed by experimental studies of enthalpies of combustion in condensed phase, vapor-pressure measurements, and differential scanning calorimetric (d.s.c.) heat-capacity measurements. Ideal-gas enthalpies of formation of cyclohexene, phthalan (2,5-dihydrobenzo-3,4-furan), isoxazole, n-octylamine, di-n-octylamine, tri-n-octylamine, phenyl isocyanate, and 1,4,5,6-tetrahydropyrimidine are reported. Two-phase (liquid + vapor) heat capacities were determined for phthalan, isoxazole, the three octylamines, and phenyl isocyanate. Liquid-phase densities along the saturation line were measured for phthalan and isoxazole at 298 to 425 K. The critical temperature and critical density of n-octylamine were determined from d.s.c. results and critical pressure derived from the fitting procedures. Fitting procedures were used to derive critical temperatures, pressures, and densities for cyclohexene (pressure and density only), phthalan, isoxazole, di-n-octylamine, and phenyl isocyanate. Group-additivity parameters or ring-correction terms are derived.

  7. SolarSyngas: Results from a virtual institute developing materials and key components for solar thermochemical fuel production

    NASA Astrophysics Data System (ADS)

    Roeb, Martin; Steinfeld, Aldo; Borchardt, Günter; Feldmann, Claus; Schmücker, Martin; Sattler, Christian; Pitz-Paal, Robert

    2016-05-01

    The Helmholtz Virtual Institute (VI) SolarSynGas brings together expertise from solar energy research and materials science to develop metal oxide based redox materials and to integrate them in a suitable way into related process technologies for two-step thermochemical production of hydrogen and carbon monoxide from water and CO2. One of the foci of experimental investigation was exploring the impact of doping on the feasibility of ceria-based materials - mainly by Zr-doping. The results indicate that a certain Zr-content enhances the reducibility and therefore the splitting performance. Increasing the Zr-content to x = 0.15 improved the specific CO2-splitting performance by 50% compared to pure ceria. This finding agrees with theoretical studies attributing the improvements to lattice modification caused by the introduction of Zr4+. Thermogravimetric relaxation experiments and equilibrium oxygen isotope exchange experiments with subsequent depth profiling analysis were carried out on ceria. As a result the reduction reaction of even dense samples of pure ceria with a grain size of about 20 µm is surface reaction controlled. The structure of the derived expression for the apparent activation energy suggests that the chemical surface exchange coefficient should show only a very weak dependence on temperature for ceria doped with lower valence cations. A solar receiver reactor exhibiting a foam-type reticulated porous ceramics made of ceria was tested. It could be shown that applying dual-scale porosity to those foams with mm-size pores for effective radiative heat transfer during reduction and μm-size pores within its struts for enhanced kinetics during oxidation allows enhancing the performance of the reactor significantly. Also a particle process concept applying solid-solid heat recovery from redox particles in a high temperature solar thermochemical process was analysed that uses ceramic spheres as solid heat transfer medium. This concept can be implemented

  8. Job Interviews: Keys for Results

    ERIC Educational Resources Information Center

    Miller, Donald S.; Catt, Stephen E.; Slocombe, Thomas E.

    2014-01-01

    Many students seem disinterested in learning to handle employment interviews effectively. This article discusses students' motivation to become skilled interviewees and steps educators and counselors can take to increase students' interest in this crucial career activity. The article also discusses mistakes students frequently make during…

  9. Morphine administration during low ovarian hormone stage results in transient over expression of fear memories in females.

    PubMed

    Perez-Torres, Emily M; Ramos-Ortolaza, Dinah L; Morales, Roberto; Santini, Edwin; Rios-Ruiz, Efrain J; Torres-Reveron, Annelyn

    2015-01-01

    Acute exposure to morphine after a traumatic event reduces trauma related symptoms in humans and conditioned fear expression in male rats. We aimed to determine whether acute administration of morphine alters consolidation of fear learning and extinction. Male and female rats in proestrus and metaestrus (high and low ovarian hormones respectively) underwent fear conditioning and received saline or morphine (2.5 mg/kg s.c.). The next day they underwent extinction. Results showed increased freezing during extinction only in the morphine metaestrus group while morphine did not affect males or proestrus females. Recall of extinction was similar on all groups. On a second experiment, a subset of rats conditioned during metaestrus was administered morphine prior to extinction producing no effects. We then measured mu opioid receptor (MOR) expression in the amygdala and periaqueductal gray (PAG) at the end of extinction (day 2). In males and proestrus females, morphine caused an increase in MOR in the amygdala but no in the PAG. In metaestrus females, morphine did not change MOR expression in either structure. These data suggests that ovarian hormones may interact with MORs in the amygdala to transiently alter memory consolidation. Morphine given after trauma to females with low ovarian hormones might increase the recall of fear responses, making recovery harder. PMID:26052274

  10. [Kindergarten Scheduling Study: Results for Administrators, Results for Teachers, Midwestern State Survey, Midwest University Professors Study. Volume I, Numbers 1-4.

    ERIC Educational Resources Information Center

    Finkelstein, Judith M.

    A comparison of full-day, alternate-day (FDAD) and half-day, every-day (HDED) kindergartens in Iowa assessed instructional time; congruence between goals and outcomes; and principal, teacher, and pupil attitudes. Findings were gathered from surveys of school administrators and teachers, as well as from questionnaires sent to directors of early…

  11. 77 FR 19619 - Notice of Extension of Time Limit for the Preliminary Results of Administrative Review of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... Requests for Revocation in Part, 76 FR 53404 (August 26, 2011). Pursuant to the time limits for... Administrative Review of the Suspension Agreement on Hot-Rolled Flat- Rolled Carbon-Quality Steel Products from... Review of the Suspension Agreement on Hot-Rolled Flat-Rolled Carbon-Quality Steel Products from...

  12. 76 FR 7813 - Amended Final Results of the 2008-2009 Antidumping Duty Administrative Review: Pure Magnesium...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ...-2009 Antidumping Duty Administrative Review of the Antidumping Duty Order, 75 FR 80791 (December 23... chemistry, form or size, unless expressly excluded from the scope of this order. Pure magnesium is a metal... materials into magnesium metal. Pure primary magnesium is used primarily as a chemical in the...

  13. How Cannabis Causes Paranoia: Using the Intravenous Administration of ∆9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia

    PubMed Central

    Freeman, Daniel; Dunn, Graham; Murray, Robin M.; Evans, Nicole; Lister, Rachel; Antley, Angus; Slater, Mel; Godlewska, Beata; Cornish, Robert; Williams, Jonathan; Di Simplicio, Martina; Igoumenou, Artemis; Brenneisen, Rudolf; Tunbridge, Elizabeth M.; Harrison, Paul J.; Harmer, Catherine J.; Cowen, Philip; Morrison, Paul D.

    2015-01-01

    Paranoia is receiving increasing attention in its own right, since it is a central experience of psychotic disorders and a marker of the health of a society. Paranoia is associated with use of the most commonly taken illicit drug, cannabis. The objective was to determine whether the principal psychoactive ingredient of cannabis—∆9-tetrahydrocannabinol (THC)—causes paranoia and to use the drug as a probe to identify key cognitive mechanisms underlying paranoia. A randomized, placebo-controlled, between-groups test of the effects of intravenous THC was conducted. A total of 121 individuals with paranoid ideation were randomized to receive placebo, THC, or THC preceded by a cognitive awareness condition. Paranoia was assessed extensively via a real social situation, an immersive virtual reality experiment, and standard self-report and interviewer measures. Putative causal factors were assessed. Principal components analysis was used to create a composite paranoia score and composite causal variables to be tested in a mediation analysis. THC significantly increased paranoia, negative affect (anxiety, worry, depression, negative thoughts about the self), and a range of anomalous experiences, and reduced working memory capacity. The increase in negative affect and in anomalous experiences fully accounted for the increase in paranoia. Working memory changes did not lead to paranoia. Making participants aware of the effects of THC had little impact. In this largest study of intravenous THC, it was definitively demonstrated that the drug triggers paranoid thoughts in vulnerable individuals. The most likely mechanism of action causing paranoia was the generation of negative affect and anomalous experiences. PMID:25031222

  14. How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to paranoia.

    PubMed

    Freeman, Daniel; Dunn, Graham; Murray, Robin M; Evans, Nicole; Lister, Rachel; Antley, Angus; Slater, Mel; Godlewska, Beata; Cornish, Robert; Williams, Jonathan; Di Simplicio, Martina; Igoumenou, Artemis; Brenneisen, Rudolf; Tunbridge, Elizabeth M; Harrison, Paul J; Harmer, Catherine J; Cowen, Philip; Morrison, Paul D

    2015-03-01

    Paranoia is receiving increasing attention in its own right, since it is a central experience of psychotic disorders and a marker of the health of a society. Paranoia is associated with use of the most commonly taken illicit drug, cannabis. The objective was to determine whether the principal psychoactive ingredient of cannabis-∆(9)-tetrahydrocannabinol (THC)-causes paranoia and to use the drug as a probe to identify key cognitive mechanisms underlying paranoia. A randomized, placebo-controlled, between-groups test of the effects of intravenous THC was conducted. A total of 121 individuals with paranoid ideation were randomized to receive placebo, THC, or THC preceded by a cognitive awareness condition. Paranoia was assessed extensively via a real social situation, an immersive virtual reality experiment, and standard self-report and interviewer measures. Putative causal factors were assessed. Principal components analysis was used to create a composite paranoia score and composite causal variables to be tested in a mediation analysis. THC significantly increased paranoia, negative affect (anxiety, worry, depression, negative thoughts about the self), and a range of anomalous experiences, and reduced working memory capacity. The increase in negative affect and in anomalous experiences fully accounted for the increase in paranoia. Working memory changes did not lead to paranoia. Making participants aware of the effects of THC had little impact. In this largest study of intravenous THC, it was definitively demonstrated that the drug triggers paranoid thoughts in vulnerable individuals. The most likely mechanism of action causing paranoia was the generation of negative affect and anomalous experiences.

  15. How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to paranoia.

    PubMed

    Freeman, Daniel; Dunn, Graham; Murray, Robin M; Evans, Nicole; Lister, Rachel; Antley, Angus; Slater, Mel; Godlewska, Beata; Cornish, Robert; Williams, Jonathan; Di Simplicio, Martina; Igoumenou, Artemis; Brenneisen, Rudolf; Tunbridge, Elizabeth M; Harrison, Paul J; Harmer, Catherine J; Cowen, Philip; Morrison, Paul D

    2015-03-01

    Paranoia is receiving increasing attention in its own right, since it is a central experience of psychotic disorders and a marker of the health of a society. Paranoia is associated with use of the most commonly taken illicit drug, cannabis. The objective was to determine whether the principal psychoactive ingredient of cannabis-∆(9)-tetrahydrocannabinol (THC)-causes paranoia and to use the drug as a probe to identify key cognitive mechanisms underlying paranoia. A randomized, placebo-controlled, between-groups test of the effects of intravenous THC was conducted. A total of 121 individuals with paranoid ideation were randomized to receive placebo, THC, or THC preceded by a cognitive awareness condition. Paranoia was assessed extensively via a real social situation, an immersive virtual reality experiment, and standard self-report and interviewer measures. Putative causal factors were assessed. Principal components analysis was used to create a composite paranoia score and composite causal variables to be tested in a mediation analysis. THC significantly increased paranoia, negative affect (anxiety, worry, depression, negative thoughts about the self), and a range of anomalous experiences, and reduced working memory capacity. The increase in negative affect and in anomalous experiences fully accounted for the increase in paranoia. Working memory changes did not lead to paranoia. Making participants aware of the effects of THC had little impact. In this largest study of intravenous THC, it was definitively demonstrated that the drug triggers paranoid thoughts in vulnerable individuals. The most likely mechanism of action causing paranoia was the generation of negative affect and anomalous experiences. PMID:25031222

  16. A mental health needs assessment of children and adolescents in post-conflict Liberia: results from a quantitative key-informant survey

    PubMed Central

    Borba, Christina P.C.; Ng, Lauren C.; Stevenson, Anne; Vesga-Lopez, Oriana; Harris, Benjamin L.; Parnarouskis, Lindsey; Gray, Deborah A.; Carney, Julia R.; Domínguez, Silvia; Wang, Edward K.S.; Boxill, Ryan; Song, Suzan J.; Henderson, David C.

    2016-01-01

    Between 1989 and 2004, Liberia experienced a devastating civil war that resulted in widespread trauma with almost no mental health infrastructure to help citizens cope. In 2009, the Liberian Ministry of Health and Social Welfare collaborated with researchers from Massachusetts General Hospital to conduct a rapid needs assessment survey in Liberia with local key informants (n = 171) to examine the impact of war and post-war events on emotional and behavioral problems of, functional limitations of, and appropriate treatment settings for Liberian youth aged 5–22. War exposure and post-conflict sexual violence, poverty, infectious disease and parental death negatively impacted youth mental health. Key informants perceived that youth displayed internalizing and externalizing symptoms and mental health-related functional impairment at home, school, work and in relationships. Medical clinics were identified as the most appropriate setting for mental health services. Youth in Liberia continue to endure the harsh social, economic and material conditions of everyday life in a protracted post-conflict state, and have significant mental health needs. Their observed functional impairment due to mental health issues further limited their access to protective factors such as education, employment and positive social relationships. Results from this study informed Liberia's first post-conflict mental health policy. PMID:26807147

  17. Quantification of key long-term risks at CO₂ sequestration sites: Latest results from US DOE's National Risk Assessment Partnership (NRAP) Project

    SciTech Connect

    Pawar, Rajesh; Bromhal, Grant; Carroll, Susan; Chu, Shaoping; Dilmore, Robert; Gastelum, Jason; Oldenburg, Curt; Stauffer, Philip; Zhang, Yingqi; Guthrie, George

    2014-12-31

    Risk assessment for geologic CO₂ storage including quantification of risks is an area of active investigation. The National Risk Assessment Partnership (NRAP) is a US-Department of Energy (US-DOE) effort focused on developing a defensible, science-based methodology and platform for quantifying risk profiles at geologic CO₂ sequestration sites. NRAP has been developing a methodology that centers round development of an integrated assessment model (IAM) using system modeling approach to quantify risks and risk profiles. The IAM has been used to calculate risk profiles with a few key potential impacts due to potential CO₂ and brine leakage. The simulation results are also used to determine long-term storage security relationships and compare the long-term storage effectiveness to IPCC storage permanence goal. Additionally, we also demonstrate application of IAM for uncertainty quantification in order to determine parameters to which the uncertainty in model results is most sensitive.

  18. Quantification of key long-term risks at CO₂ sequestration sites: Latest results from US DOE's National Risk Assessment Partnership (NRAP) Project

    DOE PAGES

    Pawar, Rajesh; Bromhal, Grant; Carroll, Susan; Chu, Shaoping; Dilmore, Robert; Gastelum, Jason; Oldenburg, Curt; Stauffer, Philip; Zhang, Yingqi; Guthrie, George

    2014-12-31

    Risk assessment for geologic CO₂ storage including quantification of risks is an area of active investigation. The National Risk Assessment Partnership (NRAP) is a US-Department of Energy (US-DOE) effort focused on developing a defensible, science-based methodology and platform for quantifying risk profiles at geologic CO₂ sequestration sites. NRAP has been developing a methodology that centers round development of an integrated assessment model (IAM) using system modeling approach to quantify risks and risk profiles. The IAM has been used to calculate risk profiles with a few key potential impacts due to potential CO₂ and brine leakage. The simulation results are alsomore » used to determine long-term storage security relationships and compare the long-term storage effectiveness to IPCC storage permanence goal. Additionally, we also demonstrate application of IAM for uncertainty quantification in order to determine parameters to which the uncertainty in model results is most sensitive.« less

  19. Patient-centered medical home initiative produced modest economic results for Veterans Health Administration, 2010-12.

    PubMed

    Hebert, Paul L; Liu, Chuan-Fen; Wong, Edwin S; Hernandez, Susan E; Batten, Adam; Lo, Sophie; Lemon, Jaclyn M; Conrad, Douglas A; Grembowski, David; Nelson, Karin; Fihn, Stephan D

    2014-06-01

    In 2010 the Veterans Health Administration (VHA) began a nationwide initiative called Patient Aligned Care Teams (PACT) that reorganized care at all VHA primary care clinics in accordance with the patient-centered medical home model. We analyzed data for fiscal years 2003-12 to assess how trends in health care use and costs changed after the implementation of PACT. We found that PACT was associated with modest increases in primary care visits and with modest decreases in both hospitalizations for ambulatory care-sensitive conditions and outpatient visits with mental health specialists. We estimated that these changes avoided $596 million in costs, compared to the investment in PACT of $774 million, for a potential net loss of $178 million in the study period. Although PACT has not generated a positive return, it is still maturing, and trends in costs and use are favorable. Adopting patient-centered care does not appear to have been a major financial risk for the VHA.

  20. Key results of the mini-dome Fresnel lens concentrator array development program under recently completed NASA and SDIO SBIR projects

    NASA Technical Reports Server (NTRS)

    Oneill, Mark J.; Piszczor, Michael F.; Fraas, Lewis M.

    1991-01-01

    Since 1986, ENTECH and the NASA Lewis Research Center have been developing a new photovoltaic concentrator system for space power applications. The unique refractive system uses small, dome shaped Fresnel lenses to focus sunlight onto high efficiency photovoltaic concentrator cells which use prismatic cell covers to further increase their performance. Highlights of the five-year development include near Air Mass Zero (AM0) Lear Jet flight testing of mini-dome lenses (90 pct. net optical efficiency achieved); tests verifying sun-pointing error tolerance with negligible power loss; simulator testing of prism-covered GaAs concentrator cells (24 pct. AM0 efficiency); testing of prism-covered Boeing GaAs/GaSb tandem cells (31 pct. AM0 efficiency); and fabrication and outdoor testing of a 36-lens/cell element panel. These test results have confirmed previous analytical predictions which indicate substantial performance improvements for this technology over current array systems. Based on program results to date, it appears than an array power density of 300 watts/sq m and a specific power of 100 watts/kg can be achieved in the near term. All components of the array appear to be readily manufacturable from space-durable materials at reasonable cost. A concise review is presented of the key results leading to the current array, and further development plans for the future are briefly discussed.

  1. Alternative method of oral administration by peanut butter pellet formulation results in target engagement of BACE1 and attenuation of gavage-induced stress responses in mice.

    PubMed

    Gonzales, C; Zaleska, M M; Riddell, D R; Atchison, K P; Robshaw, A; Zhou, H; Sukoff Rizzo, S J

    2014-11-01

    Development of novel therapeutic agents aimed at treating neurodegenerative disorders such as Alzheimer's and Parkinson's diseases require chronic and preferentially oral dosing in appropriate preclinical rodent models. Since many of these disease models involve transgenic mice that are frequently aged and fragile, the commonly used oro-gastric gavage method of drug administration often confounds measured outcomes due to repeated stress and high attrition rates caused by esophageal complications. We employed a novel drug formulation in a peanut butter (PB) pellet readily consumed by mice and compared the stress response as measured by plasma corticosterone levels relative to oral administration via traditional gavage. Acute gavage produced significant elevations in plasma corticosterone comparable to those observed in mice subjected to stress-induced hyperthermia. In contrast, corticosterone levels following consumption of PB pellets were similar to levels in naive mice and significantly lower than in mice subjected to traditional gavage. Following sub-chronic administration, corticosterone levels remained significantly higher in mice subjected to gavage, relative to mice administered PB pellets or naive controls. Furthermore, chronic 30day dosing of a BACE inhibitor administered via PB pellets to PSAPP mice resulted in expected plasma drug exposure and Aβ40 lowering consistent with drug treatment demonstrating target engagement. Taken together, this alternative method of oral administration by drug formulated in PB pellets results in the expected pharmacokinetics and pharmacodynamics with attenuated stress levels, and is devoid of the detrimental effects of repetitive oral gavage. PMID:25242810

  2. Extended Access Cocaine Self-Administration Results in Tolerance to the Dopamine-Elevating and Locomotor-Stimulating Effects of Cocaine

    PubMed Central

    Calipari, Erin S.; Ferris, Mark J.; Jones, Sara R.

    2013-01-01

    Tolerance to the neurochemical and psychoactive effects of cocaine after repeated use is a hallmark of cocaine addiction in humans. However, comprehensive studies on tolerance to the behavioral, psychoactive, and neurochemical effects of cocaine following contingent administration in rodents are lacking. We outlined the consequences of extended access cocaine self-administration as it related to tolerance to the psychomotor activating, dopamine (DA) elevating, and DA transporter (DAT) inhibiting effects of cocaine. Cocaine self-administration (1.5 mg/kg/inj; 40 inj; 5 days), which resulted in escalation of first hour intake, caused reductions in evoked DA release and reduced maximal rates of uptake through the DAT as measured by slice voltammetry in the nucleus accumbens core. Further, we report reductions in cocaine-induced uptake inhibition as measured by fast scan cyclic voltammetry, and a corresponding increase in the dose of cocaine required for 50% inhibition of DA uptake (Ki) at the DAT. Cocaine tolerance at the DAT translated to reductions in cocaine-induced DA overflow as measured by microdialysis. Additionally, cocaine-induced elevations in locomotor activity and stereotypy were reduced, while rearing behavior was enhanced in animals with a history of cocaine self-administration. Here we demonstrate both neurochemical and behavioral cocaine tolerance in an extended-access rodent model of cocaine abuse, which allows for a better understanding of the neurochemical and psychomotor tolerance that develops to cocaine in human addicts. PMID:24102293

  3. Behavior Change After 20 Months of a Radio Campaign Addressing Key Lifesaving Family Behaviors for Child Survival: Midline Results From a Cluster Randomized Trial in Rural Burkina Faso

    PubMed Central

    Sarrassat, Sophie; Meda, Nicolas; Ouedraogo, Moctar; Some, Henri; Bambara, Robert; Head, Roy; Murray, Joanna; Remes, Pieter; Cousens, Simon

    2015-01-01

    Background: In Burkina Faso, a comprehensive 35-month radio campaign addressed key, multiple family behaviors for improving under-5 child survival and was evaluated using a repeated cross-sectional, cluster randomized design. The primary outcome of the trial was postneonatal under-5 child mortality. This paper reports on behavior change achieved at midline. Method: Fourteen community radio stations in 14 geographic areas were selected based on their high listenership. Seven areas were randomly allocated to receive the intervention while the other 7 areas served as controls. The campaign was launched in March 2012. Cross-sectional surveys of about 5,000 mothers of under-5 children, living in villages close to the radio stations, were conducted at baseline (from December 2011 to February 2012) and at midline (in November 2013), after 20 months of campaigning. Statistical analyses were based on cluster-level summaries using a difference-in-difference (DiD) approach and adjusted for imbalances between arms at baseline. In addition, routine health facility data were analyzed for evidence of changes in health facility utilization. Results: At midline, 75% of women in the intervention arm reported recognizing radio spots from the campaign. There was some evidence of the campaign having positive effects on care seeking for diarrhea (adjusted DiD, 17.5 percentage points; 95% confidence interval [CI], 2.5 to 32.5; P = .03), antibiotic treatment for fast/difficult breathing (adjusted DiD, 29.6 percentage points; 95% CI, 3.5 to 55.7; P = .03), and saving money during pregnancy (adjusted DiD, 12.8 percentage points; 95% CI, 1.4 to 24.2; P = .03). For other target behaviors, there was little or no evidence of an impact of the campaign after adjustment for baseline imbalances and confounding factors. There was weak evidence of a positive correlation between the intensity of broadcasting of messages and reported changes in target behaviors. Routine health facility data

  4. Results.

    ERIC Educational Resources Information Center

    Zemsky, Robert; Shaman, Susan; Shapiro, Daniel B.

    2001-01-01

    Describes the Collegiate Results Instrument (CRI), which measures a range of collegiate outcomes for alumni 6 years after graduation. The CRI was designed to target alumni from institutions across market segments and assess their values, abilities, work skills, occupations, and pursuit of lifelong learning. (EV)

  5. 77 FR 70417 - Administrative Review of Honey From the People's Republic of China: Final Results of Antidumping...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ...'' section below. \\1\\ See Honey From the People's Republic of China: Preliminary Results of Review, 77 FR... FR 25682 (May 1, 2012). As noted above, on August 6, 2012, the Department published the Preliminary... Amendment To Final Determination: Honey from the People's Republic of China, 66 FR 59026 (December 10,...

  6. Shift Work in Rats Results in Increased Inflammatory Response after Lipopolysaccharide Administration: A Role for Food Consumption.

    PubMed

    Guerrero-Vargas, Natalí N; Guzmán-Ruiz, Mara; Fuentes, Rebeca; García, Joselyn; Salgado-Delgado, Roberto; Basualdo, María del Carmen; Escobar, Carolina; Markus, Regina P; Buijs, Ruud M

    2015-08-01

    The suprachiasmatic nucleus (SCN) drives circadian rhythms in behavioral and physiological variables, including the inflammatory response. Shift work is known to disturb circadian rhythms and is associated with increased susceptibility to develop disease. In rodents, circadian disruption due to shifted light schedules (jet lag) induced increased innate immune responses. To gain more insight into the influence of circadian disruption on the immune response, we characterized the inflammatory response in a model of rodent shift work and demonstrated that circadian disruption affected the inflammatory response to lipopolysaccharide (LPS) both in vivo and in vitro. Since food consumption is a main disturbing element in the shift work schedule, we also evaluated the inflammatory response to LPS in a group of rats that had no access to food during their working hours. Our results demonstrated that the shift work schedule decreased basal TNF-α levels in the liver but not in the circulation. Despite this, we observed that shift work induced increased cytokine response after LPS stimulation in comparison to control rats. Also, Kupffer cells (liver macrophages) isolated from shift work rats produced more TNF-α in response to in vitro LPS stimulation, suggesting important effects of circadian desynchronization on the functionality of this cell type. Importantly, the effects of shift work on the inflammatory response to LPS were prevented when food was not available during the working schedule. Together, these results show that dissociating behavior and food intake from the synchronizing drive of the SCN severely disturbs the immune response. PMID:26017928

  7. Shift Work in Rats Results in Increased Inflammatory Response after Lipopolysaccharide Administration: A Role for Food Consumption.

    PubMed

    Guerrero-Vargas, Natalí N; Guzmán-Ruiz, Mara; Fuentes, Rebeca; García, Joselyn; Salgado-Delgado, Roberto; Basualdo, María del Carmen; Escobar, Carolina; Markus, Regina P; Buijs, Ruud M

    2015-08-01

    The suprachiasmatic nucleus (SCN) drives circadian rhythms in behavioral and physiological variables, including the inflammatory response. Shift work is known to disturb circadian rhythms and is associated with increased susceptibility to develop disease. In rodents, circadian disruption due to shifted light schedules (jet lag) induced increased innate immune responses. To gain more insight into the influence of circadian disruption on the immune response, we characterized the inflammatory response in a model of rodent shift work and demonstrated that circadian disruption affected the inflammatory response to lipopolysaccharide (LPS) both in vivo and in vitro. Since food consumption is a main disturbing element in the shift work schedule, we also evaluated the inflammatory response to LPS in a group of rats that had no access to food during their working hours. Our results demonstrated that the shift work schedule decreased basal TNF-α levels in the liver but not in the circulation. Despite this, we observed that shift work induced increased cytokine response after LPS stimulation in comparison to control rats. Also, Kupffer cells (liver macrophages) isolated from shift work rats produced more TNF-α in response to in vitro LPS stimulation, suggesting important effects of circadian desynchronization on the functionality of this cell type. Importantly, the effects of shift work on the inflammatory response to LPS were prevented when food was not available during the working schedule. Together, these results show that dissociating behavior and food intake from the synchronizing drive of the SCN severely disturbs the immune response.

  8. Laboratory environment and bio-medical experience: the impact of administration technique on the quality of immune-behavior data results in stress experience

    PubMed Central

    Issam, Nessaibia; Abdelkrim, Tahraoui; Ibtissem, Chouba; Narjess, Kaarar

    2015-01-01

    Introduction: Often in an experiment, the control group and the intact group are not identified because most scientists neglect the fact that the sets of manipulation as technical administrations may be considered as an undesirable stress on the clarity of the data obtained from a scientific research specifically if it focuses on studying the effects of stress. Methods: This study was conducted in two parts using 40 male Wistar rats. The first part aimed to treat a group of rats by repeated injections i.p route (1 mL/kg) of placebo or NaCl (0.9%) and the other by direct oral administration of NaCl (0.9%). Both groups spent 1 h of jet air stress with stressed group. Our objective was to consider the effects that these manipulations would have on the validity of behavioral results (the elevated plus maze test, the open field, the light/dark box test) and immune data (immune cell count) during this stress experience. The second part was devoted to the measurement of ACTH, IL6, and CRP in these experimental groups. Results: Unlike oral administration, repeated intra-peritoneal injections cause a significant increase of plasma obtained levels of the adrenocorticotropin hormone (ACTH), interleukin-6 (IL-6) and the C-reactive protein (CRP) using injections of placebo: NaCl 0.9% (1 mL/kg) and it may have side effect on significant immune and behavioral alterations data quality induced by 1 h of air jet in the animal’s cage identified by the leukocyte formula and behavioral tests. Conclusion: In an experimental protocol conducted on animal models, it is essential to opt for painless techniques such as oral administration instead of painful injections to avoid confusion at the behavioral and immunological results from biomedical experiments specifically one that focuses on the stress study. PMID:26929920

  9. NASA, NOAA administrators nominated

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    President Ronald Reagan recently said he intended to nominate James Montgomery Beggs as NASA Administrator and John V. Byrne as NOAA Administrator. These two positions are key scientific posts that have been vacant since the start of the Reagan administration on January 20. The President also said he intends to nominate Hans Mark as NASA Deputy Administrator. At press time, Reagan had not designated his nominee for the director of the Office of Science and Technology Policy.

  10. Nonfatal Suicidal Behaviors in U.S. Army Administrative Records, 2004–2009: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

    PubMed Central

    Ursano, Robert J.; Kessler, Ronald C.; Heeringa, Steven G.; Cox, Kenneth L.; Naifeh, James A.; Fullerton, Carol S.; Sampson, Nancy A.; Kao, Tzu-Cheg; Aliaga, Pablo A.; Vegella, Patti; Mash, Holly Herberman; Buckley, Christina; Colpe, Lisa J.; Schoenbaum, Michael; Stein, Murray B.

    2015-01-01

    Objective Although the U.S. Army suicide rate is known to have risen sharply over the past decade, information about medically documented, nonfatal suicidal behaviors is far more limited. Here we examine trends and sociodemographic correlates of suicide attempts, suspicious injuries, and suicide ideation among regular Army soldiers. Methods Data come from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) Historical Administrative Data Study (HADS), which integrates administrative records for all soldiers on active duty during the years 2004 through 2009 (n = 1.66 million). Results We identified 21,740 unique regular Army soldiers with a nonfatal suicidal event documented at some point during the HADS study period. There were substantial increases in the annual incidence rates of suicide attempts (179–400/100,000 person-years) and suicide ideation (557–830/100,000 person-years), but not suspicious injuries. Using hierarchical classification rules to identify the first instance of each soldier's most severe behavior, we found increased risk of all outcomes among those who were female, non-Hispanic White, never married, lower-ranking enlisted, less educated, and of younger age when entering Army service. These sociodemographic associations significantly differed across outcomes, despite some patterns that appear similar. Conclusion Results provide a broad overview of nonfatal suicidal trends in the U.S. Army during 2004 through 2009 and demonstrate that integration of multiple administrative data systems enriches analysis of the predictors of such events. PMID:26168022

  11. Florida Keys

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Florida Keys are a chain of islands, islets and reefs extending from Virginia Key to the Dry Tortugas for about 309 kilometers (192 miles). The keys are chiefly limestone and coral formations. The larger islands of the group are Key West (with its airport), Key Largo, Sugarloaf Key, and Boca Chica Key. A causeway extends from the mainland to Key West.

    This image was acquired on October 28, 2001, by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. Science team leader; Bjorn Eng of JPL is the project manager. The Terra mission is part of NASA's Earth Science Enterprise, a long- term research effort to understand and protect our home planet. Through the study of Earth, NASA will help to provide sound science to policy and economic

  12. Key Nutrients.

    ERIC Educational Resources Information Center

    Federal Extension Service (USDA), Washington, DC.

    Lessons written to help trainer agents prepare aides for work with families in the Food and Nutrition Program are presented in this booklet. The key nutrients discussed in the 10 lessons are protein, carbohydrates, fat, calcium, iron, iodine, and Vitamins A, B, C, and D. the format of each lesson is as follows: Purpose, Presentation, Application…

  13. Results and evaluation of key comparison CCM.P-K12.1 for very low helium flow rates (leak rates)

    NASA Astrophysics Data System (ADS)

    Šetina, Janez; Vičar, Martin; Pražák, Dominik

    2015-01-01

    The Czech Metrology Institute (CMI) took part and failed to prove equivalence in the Key Comparison CCM.P-K12 of helium leak artefacts (leak rates) into vacuum. After identifying and eliminating the cause of the failure, the Institute of Metals and Technology (IMT) of Slovenia, a successful participant in CCM.P-K12, volunteered to serve as pilot and link in a following bilateral comparison of IMT and CMI that obtained designation CCM.P-K12.1 in June 2012. It was decided to perform the comparison with a glass permeation helium leak artefact at nominally 3.10-11 mol/s (7.4.10-7 mbar.L.s-1) at 23 °C. Both the laboratory standards took part in CCM.P-K12 and were considered as primary. The comparison measurements were performed in October 2012. CMI proved equivalence both with IMT and with the reference value of the key comparison CCM.P-K12. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  14. Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum.

    PubMed

    Abburi, Chandrika; Wolfman, Shannon L; Metz, Ryan A E; Kamber, Rinya; McGehee, Daniel S; McDaid, John

    2016-01-01

    Ethanol (EtOH) and nicotine are the most widely coabused drugs. Tolerance to EtOH intoxication, including motor impairment, results in greater EtOH consumption and may result in a greater likelihood of addiction. Previous studies suggest that cross-tolerance between EtOH and nicotine may contribute to the abuse potential of these drugs. Here we demonstrate that repeated intermittent administration of either EtOH or nicotine in adult male Sprague Dawley rats results in tolerance to EtOH-induced motor impairment and increased EtOH self-administration. These findings suggest that nicotine and EtOH cross-tolerance results in decreased aversive and enhanced rewarding effects of EtOH. Endocannabinoid signaling in the dorsolateral striatum (DLS) has been implicated in both EtOH tolerance and reward, so we investigated whether nicotine or EtOH pretreatment might modulate endocannabinoid signaling in this region. Using similar EtOH and nicotine pretreatment methods resulted in increased paired-pulse ratios of evoked EPSCs in enkephalin-positive medium spiny neurons in DLS slices. Thus, EtOH and nicotine pretreatment may modulate glutamatergic synapses in the DLS presynaptically. Bath application of the CB1 receptor agonist Win 55,2-212 increased the paired-pulse ratio of evoked EPSCs in control slices, while Win 55,2-212 had no effect on paired-pulse ratio in slices from either EtOH- or nicotine-pretreated rats. Consistent with these effects, nicotine pretreatment occluded LTD induction by high-frequency stimulation of the corticostriatal inputs to the dorsolateral striatum. These results suggest that nicotine and EtOH pretreatment modulates striatal synapses to induce tolerance to the motor-impairing effects of EtOH, which may contribute to nicotine and EtOH coabuse. PMID:27517088

  15. Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum

    PubMed Central

    Abburi, Chandrika; Wolfman, Shannon L.; Metz, Ryan A. E.; Kamber, Rinya

    2016-01-01

    Abstract Ethanol (EtOH) and nicotine are the most widely coabused drugs. Tolerance to EtOH intoxication, including motor impairment, results in greater EtOH consumption and may result in a greater likelihood of addiction. Previous studies suggest that cross-tolerance between EtOH and nicotine may contribute to the abuse potential of these drugs. Here we demonstrate that repeated intermittent administration of either EtOH or nicotine in adult male Sprague Dawley rats results in tolerance to EtOH-induced motor impairment and increased EtOH self-administration. These findings suggest that nicotine and EtOH cross-tolerance results in decreased aversive and enhanced rewarding effects of EtOH. Endocannabinoid signaling in the dorsolateral striatum (DLS) has been implicated in both EtOH tolerance and reward, so we investigated whether nicotine or EtOH pretreatment might modulate endocannabinoid signaling in this region. Using similar EtOH and nicotine pretreatment methods resulted in increased paired-pulse ratios of evoked EPSCs in enkephalin-positive medium spiny neurons in DLS slices. Thus, EtOH and nicotine pretreatment may modulate glutamatergic synapses in the DLS presynaptically. Bath application of the CB1 receptor agonist Win 55,2-212 increased the paired-pulse ratio of evoked EPSCs in control slices, while Win 55,2-212 had no effect on paired-pulse ratio in slices from either EtOH- or nicotine-pretreated rats. Consistent with these effects, nicotine pretreatment occluded LTD induction by high-frequency stimulation of the corticostriatal inputs to the dorsolateral striatum. These results suggest that nicotine and EtOH pretreatment modulates striatal synapses to induce tolerance to the motor-impairing effects of EtOH, which may contribute to nicotine and EtOH coabuse. PMID:27517088

  16. Senior Administrators Should Have Administrative Contracts.

    ERIC Educational Resources Information Center

    Posner, Gary J.

    1987-01-01

    Recognizing that termination is viewed by the employee as the equivalent to capital punishment of a career, an administrative contract can reduce the emotional and financial entanglements that often result. Administrative contracts are described. (MLW)

  17. Prolactin administration during early postnatal life decreases hippocampal and olfactory bulb neurogenesis and results in depressive-like behavior in adulthood.

    PubMed

    Lajud, Naima; Gonzalez-Zapien, Rubén; Roque, Angélica; Tinajero, Eréndira; Valdez, Juan José; Clapp, Carmen; Torner, Luz

    2013-11-01

    Tight regulation of hormone and neurochemical milieu during developmental periods is critical for adequate physiological functions. For instance, activation of peptide systems during early life stress induces morphological changes in the brain resulting in depression and anxiety disorders. Prolactin (PRL) exerts different actions within the brain; it regulates neurogenesis and modulates neuroendocrine functions in the adult. However, PRL effects during early postnatal life are hardly known. Therefore, we examined whether neonatal administration of PRL influences cell survival in the hippocampal dentate gyrus (DG) and in the olfactory bulb (OB) and whether such influence results in behavioral consequences in adulthood. PRL-treated rat pups (13 mg/kg; PND1 to PND14), injected with BrdU at postnatal day 5 (PND5), showed a decrease in the density of DG BrdU/DCX and BrdU/NeuN-positive cells that survive at PND15. Similarly, PRL treatment decreased the density of BrdU+ cells in the OB compared with VEH. Fluorojade B analysis showed no significant changes in the amount of cell death in the DG between the groups. Postnatal PRL administration induced a passive coping strategy in the forced swimming test in male and female adult rats when compared with control and vehicle groups. Corticosterone endogenous levels at PND12 were not affected by PRL or VEH treatment. Altogether, these results suggest that opposed to its effects in the adult, postnatal PRL treatment affects neurogenesis and results in psychopathology later in life. High PRL levels, as observed in neonates under several pathological states, might contribute to detrimental effects on the developing brain.

  18. Traditional Chinese medicine and sports drug testing: identification of natural steroid administration in doping control urine samples resulting from musk (pod) extracts.

    PubMed

    Thevis, Mario; Schänzer, Wilhelm; Geyer, Hans; Thieme, Detlef; Grosse, Joachim; Rautenberg, Claudia; Flenker, Ulrich; Beuck, Simon; Thomas, Andreas; Holland, Ruben; Dvorak, Jiri

    2013-01-01

    The administration of musk extract, that is, ingredients obtained by extraction of the liquid secreted from the preputial gland or resulting grains of the male musk deer (eg, Moschus moschiferus), has been recommended in Traditional Chinese Medicine (TCM) applications and was listed in the Japanese pharmacopoeia for various indications requiring cardiovascular stimulation, anti-inflammatory medication or androgenic hormone therapy. Numerous steroidal components including cholesterol, 5α-androstane-3,17-dione, 5β-androstane-3,17-dione, androsterone, etiocholanolone, epiandrosterone, 3β-hydroxy-androst-5-en-17-one, androst-4-ene-3,17-dione and the corresponding urea adduct 3α-ureido-androst-4-en-17-one were characterised as natural ingredients of musk over several decades, implicating an issue concerning doping controls if used for the treatment of elite athletes. In the present study, the impact of musk extract administration on sports drug testing results of five females competing in an international sporting event is reported. In the course of routine doping controls, adverse analytical findings concerning the athletes' steroid profile, corroborated by isotope-ratio mass spectrometry (IRMS) data, were obtained. The athletes' medical advisors admitted the prescription of TCM-based musk pod preparations and provided musk pod samples for comparison purposes to clarify the antidoping rule violation. Steroid profiles, IRMS results, literature data and a musk sample obtained from a living musk deer of a local zoo conclusively demonstrated the use of musk pod extracts in all cases which, however, represented a doping offence as prohibited anabolic-androgenic steroids were administered.

  19. Medicaid program; allocation of enhanced federal matching funds for increased administrative costs resulting from welfare reform--HCFA. Notice with comment period.

    PubMed

    1997-05-14

    This notice with comment period announces the methodology used to determine the allocation, among the States and certain Territories, of a $500 million fund to assist them with the additional expenses attributable to eligibility determinations incurred as a result of the provisions of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996, which decouples Medicaid eligibility from receipt of cash assistance for families and children. Also, it announces the actual allocation amount for each State and Territory. The special fund is available for matching a State's or Territory's allowable administrative expenditures incurred only during Federal fiscal years 1997 through 2000, and only during the first 12 calendar quarters in which the State's Temporary Assistance to Needy Families program, which replaced the Aid to Families with Dependent Children program, is in effect after August 21, 1996. PMID:10167530

  20. Practical and Secure Recovery of Disk Encryption Key Using Smart Cards

    NASA Astrophysics Data System (ADS)

    Omote, Kazumasa; Kato, Kazuhiko

    In key-recovery methods using smart cards, a user can recover the disk encryption key in cooperation with the system administrator, even if the user has lost the smart card including the disk encryption key. However, the disk encryption key is known to the system administrator in advance in most key-recovery methods. Hence user's disk data may be read by the system administrator. Furthermore, if the disk encryption key is not known to the system administrator in advance, it is difficult to achieve a key authentication. In this paper, we propose a scheme which enables to recover the disk encryption key when the user's smart card is lost. In our scheme, the disk encryption key is not preserved anywhere and then the system administrator cannot know the key before key-recovery phase. Only someone who has a user's smart card and knows the user's password can decrypt that user's disk data. Furthermore, we measured the processing time required for user authentication in an experimental environment using a virtual machine monitor. As a result, we found that this processing time is short enough to be practical.

  1. Validation and ease of use of a new pen device for self-administration of recombinant human growth hormone: results from a two-center usability study

    PubMed Central

    Rapaport, Robert; Saenger, Paul; Schmidt, Heinrich; Hasegawa, Yukihiro; Colle, Michel; Loche, Sandro; Marcantonio, Sandra; Bonfig, Walter; Zabransky, Markus; Lifshitz, Fima

    2013-01-01

    Close adherence to the recommended treatment regimen is important for the success of recombinant human growth hormone therapy, although nonadherence can be common. Ease of use and safety during use/storage are among several important factors in the design of a growth hormone injection device intended for long-term use. This study was performed to validate the usability and assess the ease of use of a new pen device (SurePal™) that has been developed to support daily administration of the recombinant human growth hormone product, Omnitrope® (somatropin). The primary objectives of the study were to assess if study participants, representing intended users of the pen in clinical practice, were able to perform an injection procedure into an injection pad effectively and safely and disassemble the pen without receiving a needlestick injury. A total of 106 participants (61 adults and 45 children/adolescents) were enrolled at two study centers (one in the US, one in Germany). Results for both primary usability tasks met the predefined acceptance criteria, with >85% of participants successfully performing each task. All of the other tasks/handling steps assessed were also successfully performed by most participants, with high success rates reflected in the high proportion of participants who classified each task as “very easy” or “easy”. After a second use of the device, 87%–97% of participants rated it as “very easy” or “easy” to use. In summary, the new pen device is safe and easy to use for both adults and children, and will help to support effective, long-term daily administration of the recombinant human growth hormone product, Omnitrope®. PMID:24039458

  2. Validation and ease of use of a new pen device for self-administration of recombinant human growth hormone: results from a two-center usability study.

    PubMed

    Rapaport, Robert; Saenger, Paul; Schmidt, Heinrich; Hasegawa, Yukihiro; Colle, Michel; Loche, Sandro; Marcantonio, Sandra; Bonfig, Walter; Zabransky, Markus; Lifshitz, Fima

    2013-01-01

    Close adherence to the recommended treatment regimen is important for the success of recombinant human growth hormone therapy, although nonadherence can be common. Ease of use and safety during use/storage are among several important factors in the design of a growth hormone injection device intended for long-term use. This study was performed to validate the usability and assess the ease of use of a new pen device (SurePal™) that has been developed to support daily administration of the recombinant human growth hormone product, Omnitrope® (somatropin). The primary objectives of the study were to assess if study participants, representing intended users of the pen in clinical practice, were able to perform an injection procedure into an injection pad effectively and safely and disassemble the pen without receiving a needlestick injury. A total of 106 participants (61 adults and 45 children/adolescents) were enrolled at two study centers (one in the US, one in Germany). Results for both primary usability tasks met the predefined acceptance criteria, with >85% of participants successfully performing each task. All of the other tasks/handling steps assessed were also successfully performed by most participants, with high success rates reflected in the high proportion of participants who classified each task as "very easy" or "easy". After a second use of the device, 87%-97% of participants rated it as "very easy" or "easy" to use. In summary, the new pen device is safe and easy to use for both adults and children, and will help to support effective, long-term daily administration of the recombinant human growth hormone product, Omnitrope®.

  3. Strength of object representation: its key role in object-based attention for determining the competition result between Gestalt and top-down objects.

    PubMed

    Zhao, Jingjing; Wang, Yonghui; Liu, Donglai; Zhao, Liang; Liu, Peng

    2015-10-01

    It was found in previous studies that two types of objects (rectangles formed according to the Gestalt principle and Chinese words formed in a top-down fashion) can both induce an object-based effect. The aim of the present study was to investigate how the strength of an object representation affects the result of the competition between these two types of objects based on research carried out by Liu, Wang and Zhou [(2011) Acta Psychologica, 138(3), 397-404]. In Experiment 1, the rectangles were filled with two different colors to increase the strength of Gestalt object representation, and we found that the object effect changed significantly for the different stimulus types. Experiment 2 used Chinese words with various familiarities to manipulate the strength of the top-down object representation. As a result, the object-based effect induced by rectangles was observed only when the Chinese word familiarity was low. These results suggest that the strength of object representation determines the result of competition between different types of objects. PMID:26041271

  4. New species of Diabrotica Chevrolat (Coleoptera: Chrysomelidae: Galerucinae) and a key to Diabrotica and related genera: results of a synopsis of North and Central American Diabrotica species

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The following 18 new species of Diabrotica are described and illustrated as a result of the synopsis of North and Centrla American species: D. barclayi nov. sp. Guatemala, D. caveyi nov. sp. Costa Rica, D. costaricensis nov. sp. Costa Rica, D. dmitryogloblini nov. sp. Mexico, D. duckworthae nov. sp....

  5. Strength of object representation: its key role in object-based attention for determining the competition result between Gestalt and top-down objects.

    PubMed

    Zhao, Jingjing; Wang, Yonghui; Liu, Donglai; Zhao, Liang; Liu, Peng

    2015-10-01

    It was found in previous studies that two types of objects (rectangles formed according to the Gestalt principle and Chinese words formed in a top-down fashion) can both induce an object-based effect. The aim of the present study was to investigate how the strength of an object representation affects the result of the competition between these two types of objects based on research carried out by Liu, Wang and Zhou [(2011) Acta Psychologica, 138(3), 397-404]. In Experiment 1, the rectangles were filled with two different colors to increase the strength of Gestalt object representation, and we found that the object effect changed significantly for the different stimulus types. Experiment 2 used Chinese words with various familiarities to manipulate the strength of the top-down object representation. As a result, the object-based effect induced by rectangles was observed only when the Chinese word familiarity was low. These results suggest that the strength of object representation determines the result of competition between different types of objects.

  6. Do Prescription Drug Ads Tell Consumers Enough About Benefits and Side Effects? Results From the Health Information National Trends Survey, Fourth Administration.

    PubMed

    Sullivan, Helen W; Campbell, Miriam

    2015-01-01

    Direct-to-consumer prescription drug advertising (DTCA) is a major source of consumer information about prescription drugs. The present study updates 2002 U.S. Food and Drug Administration phone survey questions that found that 44% and 61% of consumers thought that DTCA did not include enough information about benefits and risks, respectively. The present study was administered by mail using a nationally representative sample, and provides a more in-depth understanding of how these beliefs relate to demographic and health characteristics. Data collected from 3,959 respondents to the National Cancer Institute's 2011 Health Information National Trends Survey find results similar to the 2002 survey: 46% and 52% of respondents thought that DCTA did not include enough information about benefits and risks, respectively. Respondents fell into four groups: 23% agreed that DTCA tells enough about drug benefits and risks, 41% disagreed, 18% expressed no opinion, and 18% had discordant beliefs. DTCA attitudes were negatively associated with education, income, and whether respondents purchase prescription drugs; attitudes were positively associated with whether respondents understand prescription drug information. This study confirms that a plurality of Americans believe that DTCA does not include enough information about benefits and risks, suggesting that the educational effect of DTCA could be improved.

  7. Alkaline Leaching of Key, Non-Radioactive Components from Simulants and Hanford Tank Sludge 241-S-110: Results of FY01 Studies

    SciTech Connect

    Rapko, Brian M.; Vienna, John D.; Sinkov, Serguei I.; Kim, Jinseong; Cisar, Alan J.

    2002-09-10

    This study addressed three aspects in selected alkaline leaching: first, the use of oxidants persulfate, permanganate, and ferrate as selective chromium-leaching agents from washed Hanford Tank S-110 solids under varying conditions of hydroxide concentration, temperature, and time was investigated. Second, the selective dissolution of solids containing mercury(II) oxide under alkaline conditions was examined. Various compounds were studied for their effectiveness in dissolving mercury under varying conditions of time, temperature, and hydroxide concentration in the leachate. Three compounds were studied: cysteine, iodide, and diethyldithiophosphoric acid (DEDTPA). Finally, the possibility of whether an oxidant bound to an anion-exchange resin can be used to effectively oxidize chromium(III) in alkaline solutions was addressed. The experimental results remain ambiguous to date; further work is required to reach any definitive conclusions as to the effectiveness of this approach.

  8. Modeling present hydrological conditions as a key to predict the future - results from a case study of a periglacial catchment in Greenland

    NASA Astrophysics Data System (ADS)

    Johansson, E.; Lindborg, T.; Berglund, S.

    2015-12-01

    The routing of water through periglacial landscapes is closely connected to the presence of permafrost, and freezing and thawing processes. To predict responses in the landscape to climate driven changes, we need to better understand the present day hydrology. The present hydrological processes, and the uncertainties in the data used to describe them, must be investigated and understood before we can develop models describing possible future conditions. In this work we have studied the hydrology of a catchment in the Kangerlussuaq region, Greenland. Johansson et al. (2015) presented a hydrological model of the catchment based on a new hydrological and meteorological data set from the catchment area. The present water balance was quantified, and the spatial and seasonal dynamics of the main hydrological fluxes were presented. It was shown that the model was able to reproduce the measured lake level dynamics and the measured components of the water balance. Based on this work we have used the numerical model to investigate the sensitivity in hydrological responses to different meteorological, geological and geometrical model input data. The aim with this study is to investigate the importance of the use of local data, but also to highlight the importance of present day site understanding when developing and applying the model for predicting responses to a changing climate. The results show that the site specific model is highly sensitive to the meteorological input data. Driving the model with precipitation data from a meteorological station only 30 km away from the catchment instead of local data from the studied catchment, or using local precipitation data not corrected for wind and adhesion losses, resulted in large discrepancies between measured and calculated lake levels. The modelled intra-annual dynamics of the active layer groundwater was shown to be sensitive both to the applied soil temperatures but also to the active layer depth and sediment stratigraphy.

  9. Mortality as a key driver of the spatial distribution of aboveground biomass in Amazonian forests: results from a Dynamic Vegetation Model

    NASA Astrophysics Data System (ADS)

    Delbart, N.; Ciais, P.; Chave, J.; Viovy, N.; Malhi, Y.; Le Toan, T.

    2010-04-01

    Dynamic Vegetation Models (DVMs) simulate energy, water and carbon fluxes between the ecosystem and the atmosphere, between the vegetation and the soil, and between plant organs. They also estimate the potential biomass of a forest in equilibrium having grown under a given climate and atmospheric CO2 level. In this study, we evaluate the above ground woody biomass (AGWB) and the above ground woody Net Primary Productivity (NPPAGW) simulated by the DVM ORCHIDEE across Amazonian forests, by comparing the simulation results to a large set of ground measurements (220 sites for biomass, 104 sites for NPPAGW). We found that the NPPAGW is on average overestimated by 63%. We also found that the fraction of biomass that is lost through mortality is 85% too high. These model biases nearly compensate each other to give an average simulated AGWB close to the ground measurement average. Nevertheless, the simulated AGWB spatial distribution differs significantly from the observations. Then, we analyse the discrepancies in biomass with regards to discrepancies in NPPAGW and those in the rate of mortality. When we correct for the error in NPPAGW, the errors on the spatial variations in AGWB are exacerbated, showing clearly that a large part of the misrepresentation of biomass comes from a wrong modelling of mortality processes. Previous studies showed that Amazonian forests with high productivity have a higher mortality rate than forests with lower productivity. We introduce this relationship, which results in strongly improved modelling of biomass and of its spatial variations. We discuss the possibility of modifying the mortality modelling in ORCHIDEE, and the opportunity to improve forest productivity modelling through the integration of biomass measurements, in particular from remote sensing.

  10. Mortality as a key driver of the spatial distribution of aboveground biomass in Amazonian forest: results from a dynamic vegetation model

    NASA Astrophysics Data System (ADS)

    Delbart, N.; Ciais, P.; Chave, J.; Viovy, N.; Malhi, Y.; Le Toan, T.

    2010-10-01

    Dynamic Vegetation Models (DVMs) simulate energy, water and carbon fluxes between the ecosystem and the atmosphere, between the vegetation and the soil, and between plant organs. They also estimate the potential biomass of a forest in equilibrium having grown under a given climate and atmospheric CO2 level. In this study, we evaluate the Above Ground Woody Biomass (AGWB) and the above ground woody Net Primary Productivity (NPPAGW) simulated by the DVM ORCHIDEE across Amazonian forests, by comparing the simulation results to a large set of ground measurements (220 sites for biomass, 104 sites for NPPAGW). We found that the NPPAGW is on average overestimated by 63%. We also found that the fraction of biomass that is lost through mortality is 85% too high. These model biases nearly compensate each other to give an average simulated AGWB close to the ground measurement average. Nevertheless, the simulated AGWB spatial distribution differs significantly from the observations. Then, we analyse the discrepancies in biomass with regards to discrepancies in NPPAGW and those in the rate of mortality. When we correct for the error in NPPAGW, the errors on the spatial variations in AGWB are exacerbated, showing clearly that a large part of the misrepresentation of biomass comes from a wrong modelling of mortality processes. Previous studies showed that Amazonian forests with high productivity have a higher mortality rate than forests with lower productivity. We introduce this relationship, which results in strongly improved modelling of biomass and of its spatial variations. We discuss the possibility of modifying the mortality modelling in ORCHIDEE, and the opportunity to improve forest productivity modelling through the integration of biomass measurements, in particular from remote sensing.

  11. Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.

    PubMed

    Dolatshad, H; Pellagatti, A; Fernandez-Mercado, M; Yip, B H; Malcovati, L; Attwood, M; Przychodzen, B; Sahgal, N; Kanapin, A A; Lockstone, H; Scifo, L; Vandenberghe, P; Papaemmanuil, E; Smith, C W J; Campbell, P J; Ogawa, S; Maciejewski, J P; Cazzola, M; Savage, K I; Boultwood, J

    2015-05-01

    The splicing factor SF3B1 is the most commonly mutated gene in the myelodysplastic syndrome (MDS), particularly in patients with refractory anemia with ring sideroblasts (RARS). We investigated the functional effects of SF3B1 disruption in myeloid cell lines: SF3B1 knockdown resulted in growth inhibition, cell cycle arrest and impaired erythroid differentiation and deregulation of many genes and pathways, including cell cycle regulation and RNA processing. MDS is a disorder of the hematopoietic stem cell and we thus studied the transcriptome of CD34(+) cells from MDS patients with SF3B1 mutations using RNA sequencing. Genes significantly differentially expressed at the transcript and/or exon level in SF3B1 mutant compared with wild-type cases include genes that are involved in MDS pathogenesis (ASXL1 and CBL), iron homeostasis and mitochondrial metabolism (ALAS2, ABCB7 and SLC25A37) and RNA splicing/processing (PRPF8 and HNRNPD). Many genes regulated by a DNA damage-induced BRCA1-BCLAF1-SF3B1 protein complex showed differential expression/splicing in SF3B1 mutant cases. This is the first study to determine the target genes of SF3B1 mutation in MDS CD34(+) cells. Our data indicate that SF3B1 has a critical role in MDS by affecting the expression and splicing of genes involved in specific cellular processes/pathways, many of which are relevant to the known RARS pathophysiology, suggesting a causal link.

  12. Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

    PubMed Central

    Dolatshad, H; Pellagatti, A; Fernandez-Mercado, M; Yip, B H; Malcovati, L; Attwood, M; Przychodzen, B; Sahgal, N; Kanapin, A A; Lockstone, H; Scifo, L; Vandenberghe, P; Papaemmanuil, E; Smith, C W J; Campbell, P J; Ogawa, S; Maciejewski, J P; Cazzola, M; Savage, K I; Boultwood, J

    2015-01-01

    The splicing factor SF3B1 is the most commonly mutated gene in the myelodysplastic syndrome (MDS), particularly in patients with refractory anemia with ring sideroblasts (RARS). We investigated the functional effects of SF3B1 disruption in myeloid cell lines: SF3B1 knockdown resulted in growth inhibition, cell cycle arrest and impaired erythroid differentiation and deregulation of many genes and pathways, including cell cycle regulation and RNA processing. MDS is a disorder of the hematopoietic stem cell and we thus studied the transcriptome of CD34+ cells from MDS patients with SF3B1 mutations using RNA sequencing. Genes significantly differentially expressed at the transcript and/or exon level in SF3B1 mutant compared with wild-type cases include genes that are involved in MDS pathogenesis (ASXL1 and CBL), iron homeostasis and mitochondrial metabolism (ALAS2, ABCB7 and SLC25A37) and RNA splicing/processing (PRPF8 and HNRNPD). Many genes regulated by a DNA damage-induced BRCA1–BCLAF1–SF3B1 protein complex showed differential expression/splicing in SF3B1 mutant cases. This is the first study to determine the target genes of SF3B1 mutation in MDS CD34+ cells. Our data indicate that SF3B1 has a critical role in MDS by affecting the expression and splicing of genes involved in specific cellular processes/pathways, many of which are relevant to the known RARS pathophysiology, suggesting a causal link. PMID:25428262

  13. Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conserving surgery enhances late toxicities: Long-term results of the ARCOSEIN multicenter randomized study

    SciTech Connect

    Toledano, Alain . E-mail: alain.toledano@gmail.com; Garaud, Pascal; Serin, Daniel; Fourquet, Alain; Bosset, Jean-Francois; Breteau, Noel; Body, Gilles; Azria, David; Le Floch, Olivier; Calais, Gilles

    2006-06-01

    Purpose: In 1996, a multicenter randomized study was initiated that compared sequential vs. concurrent adjuvant chemotherapy (CT) with radiation therapy (RT) after breast-conserving surgery (ARCOSEIN study). After a median follow-up of 6.7 years (range, 4.3-9 years), we decided to prospectively evaluate the late effects of these 2 strategies. Methods and Materials: A total of 297 patients from the 5 larger participating institutions were asked to report for a follow-up examination. Seventy-two percent (214 patients) were eligible for evaluation of late toxicity. After breast-conserving surgery, patients were treated either with sequential treatment with CT first followed by RT (Arm A) or CT administered concurrently with RT (Arm B). In all patients, CT regimen consisted of mitoxantrone (12 mg/m{sup 2}), 5-FU (500 mg/m{sup 2}), and cyclophosphamide (500 mg/m{sup 2}), 6 cycles (Day 1 to Day 21). Conventional RT was delivered to the whole breast by administration of a 2 Gy per fraction protocol to a total dose of 50 Gy ({+-} boost to the primary tumor bed). The assessment of toxicity was blinded to treatment and was graded by the radiation oncologist, according to the LENT/SOMA scale. Skin pigmentation was also evaluated according to a personal 5-points scoring system (excellent, good, moderate, poor, very poor). Results: Among the 214 evaluable patients, 107 were treated in each arm. The 2 populations were homogeneous for patient, tumor, and treatment characteristics. Subcutaneous fibrosis (SF), telangectasia (T), skin pigmentation (SP), and breast atrophy (BA) were significantly increased in Arm B. No statistical difference was observed between the 2 arms of the study concerning Grade 2 or higher pain, breast edema, or lymphedema. No deaths were caused by late toxicity. Conclusion: After breast-conserving surgery, the concurrent use of CT with RT is significantly associated with an increase incidence of Grade 2 or greater late side effects.

  14. Key Results of Interaction Models with Centering

    ERIC Educational Resources Information Center

    Afshartous, David; Preston, Richard A.

    2011-01-01

    We consider the effect on estimation of simultaneous variable centering and interaction effects in linear regression. We technically define, review, and amplify many of the statistical issues for interaction models with centering in order to create a useful and compact reference for teachers, students, and applied researchers. In addition, we…

  15. 78 FR 79061 - Noise Exposure Map Notice; Key West International Airport, Key West, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... Federal Aviation Administration Noise Exposure Map Notice; Key West International Airport, Key West, FL... Key West International Airport under the provisions of the Aviation Safety and Noise Abatement Act and...: This notice announces that the FAA finds that the Noise Exposure Maps submitted for the Key...

  16. Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study

    PubMed Central

    Harding-Esch, Emma; Jofre-Bonet, Mireia; Dhanjal, Jaskiran K.; Burr, Sarah; Edwards, Tansy; Holland, Martin; Sillah, Ansumana; West, Sheila; Lietman, Tom; Keenan, Jeremy; Mabey, David; Bailey, Robin

    2015-01-01

    Background Mass drug administration (MDA) treatment of active trachoma with antibiotic is recommended to be initiated in any district where the prevalence of trachoma inflammation, follicular (TF) is ≥10% in children aged 1–9 years, and then to continue for at least three annual rounds before resurvey. In The Gambia the PRET study found that discontinuing MDA based on testing a sample of children for ocular Chlamydia trachomatis(Ct) infection after one MDA round had similar effects to continuing MDA for three rounds. Moreover, one round of MDA reduced disease below the 5% TF threshold. We compared the costs of examining a sample of children for TF, and of testing them for Ct, with those of MDA rounds. Methods The implementation unit in PRET The Gambia was a census enumeration area (EA) of 600–800 people. Personnel, fuel, equipment, consumables, data entry and supervision costs were collected for census and treatment of a sample of EAs and for the examination, sampling and testing for Ct infection of 100 individuals within them. Programme costs and resource savings from testing and treatment strategies were inferred for the 102 EAs in the study area, and compared. Results Census costs were $103.24 per EA plus initial costs of $108.79. MDA with donated azithromycin cost $227.23 per EA. The mean cost of examining and testing 100 children was $796.90 per EA, with Ct testing kits costing $4.80 per result. A strategy of testing each EA for infection is more expensive than two annual rounds of MDA unless the kit cost is less than $1.38 per result. However stopping or deciding not to initiate treatment in the study area based on testing a sample of EAs for Ct infection (or examining children in a sample of EAs) creates savings relative to further unnecessary treatments. Conclusion Resources may be saved by using tests for chlamydial infection or clinical examination to determine that initial or subsequent rounds of MDA for trachoma are unnecessary. PMID:25901349

  17. Collaborative Behaviors Practiced by Teachers and Their Administrators Resulting in Increased California High School Exit Exam Pass Rates for Students with Learning Disabilities

    ERIC Educational Resources Information Center

    Everett, Katherine E.

    2013-01-01

    Purpose. The purpose of this replication study was to describe the extent to which seven collaborative behaviors were demonstrated by general education teachers assigned students with disabilities, education specialists, and their administrators in selected California high schools that exceeded the state average pass rate for 10th-grade students…

  18. Listening to the Voices of Beginning Teachers: Providing Meaningful Administrative Support Is a Moral Act and Results in Increasing Retention among Beginning Educators

    ERIC Educational Resources Information Center

    Rumley, Mark Alvis

    2010-01-01

    The purpose of this qualitative study was to understand and "make sense" of how beginning teachers experience and define lack of principal/administrative support during their beginning years of teaching. Utilizing grounded theory as a conceptual framework, I sought to deconstruct the stories and lived experiences of nine beginning teachers across…

  19. Key Skills Influencing Student Achievement

    ERIC Educational Resources Information Center

    Balch, Tonya; Gruenert, Steve

    2009-01-01

    A predictive, non-experimental, cross-sectional design (Johnson, 2001) was used to conduct a study to determine if elementary administrators' key counseling skills and select demographics predicted state-level student performance indicators in their respective schools. A secondary purpose of this study was to develop a valid and reliable on-line…

  20. Administrative Synergy

    ERIC Educational Resources Information Center

    Hewitt, Kimberly Kappler; Weckstein, Daniel K.

    2012-01-01

    One of the biggest obstacles to overcome in creating and sustaining an administrative professional learning community (PLC) is time. Administrators are constantly deluged by the tyranny of the urgent. It is a Herculean task to carve out time for PLCs, but it is imperative to do so. In this article, the authors describe how an administrative PLC…

  1. Adult Learners in Higher Education: Barriers to Success and Strategies to Improve Results. Employment and Training Administration. Occasional Paper 2007-03

    ERIC Educational Resources Information Center

    Kazis, Richard; Callahan, Abigail; Davidson, Chris; McLeod, Annie; Bosworth, Brian; Choitz, Vickie; Hoops, John

    2007-01-01

    This reports synthesizes the research literature on the challenges facing adult learners in higher education today and emerging strategies for increasing the number of adults over 24 who earn college credentials and degrees. This synthesis is meant to provide perspectives on key issues facing adults as more and more of them see the need for higher…

  2. Mediated semiquantum key distribution

    NASA Astrophysics Data System (ADS)

    Krawec, Walter O.

    2015-03-01

    In this work, we design a quantum key distribution protocol, allowing two limited semiquantum or "classical" users to establish a shared secret key with the help of a fully quantum server. A semiquantum user can prepare and measure qubits only in the computational basis and so must rely on this quantum server to produce qubits in alternative bases and also to perform alternative measurements. However, we assume that the server is untrusted and we prove the unconditional security of our protocol even in the worst case: when this quantum server is an all-powerful adversary. We also compute a lower bound of the key rate of our protocol, in the asymptotic scenario, as a function of the observed error rate in the channel, allowing us to compute the maximally tolerated error of our protocol. Our results show that a semiquantum protocol may hold similar security to a fully quantum one.

  3. Administrative Ecology

    ERIC Educational Resources Information Center

    McGarity, Augustus C., III; Maulding, Wanda

    2007-01-01

    This article discusses how all four facets of administrative ecology help dispel the claims about the "impossibility" of the superintendency. These are personal ecology, professional ecology, organizational ecology, and community ecology. Using today's superintendency as an administrative platform, current literature describes a preponderance of…

  4. Administrative Support.

    ERIC Educational Resources Information Center

    Doran, Dorothy; And Others

    This guide is intended to assist business education teachers in administrative support courses. The materials presented are based on the Arizona validated occupational competencies and tasks for the occupations of receptionist, secretary, and administrative assistant. Word processing skills have been infused into each of the three sections. The…

  5. Cryptographic Key Management System

    SciTech Connect

    No, author

    2014-02-21

    This report summarizes the outcome of U.S. Department of Energy (DOE) contract DE-OE0000543, requesting the design of a Cryptographic Key Management System (CKMS) for the secure management of cryptographic keys for the energy sector infrastructure. Prime contractor Sypris Electronics, in collaboration with Oak Ridge National Laboratories (ORNL), Electric Power Research Institute (EPRI), Valicore Technologies, and Purdue University's Center for Education and Research in Information Assurance and Security (CERIAS) and Smart Meter Integration Laboratory (SMIL), has designed, developed and evaluated the CKMS solution. We provide an overview of the project in Section 3, review the core contributions of all contractors in Section 4, and discuss bene ts to the DOE in Section 5. In Section 6 we describe the technical construction of the CKMS solution, and review its key contributions in Section 6.9. Section 7 describes the evaluation and demonstration of the CKMS solution in different environments. We summarize the key project objectives in Section 8, list publications resulting from the project in Section 9, and conclude with a discussion on commercialization in Section 10 and future work in Section 11.

  6. Perceptions of behavioral health care among veterans with substance use disorders: results from a national evaluation of mental health services in the Veterans Health Administration.

    PubMed

    Blonigen, Daniel M; Bui, Leena; Harris, Alex H S; Hepner, Kimberly A; Kivlahan, Daniel R

    2014-08-01

    Understanding patients' perceptions of care is essential for health care systems. We examined predictors of perceptions of behavioral health care (satisfaction with care, helpfulness of care, and perceived improvement) among veterans with substance use disorders (SUD; n = 1,581) who participated in a phone survey as part of a national evaluation of mental health services in the U.S. Veterans Health Administration. In multivariate analyses, SUD specialty care utilization and higher mental health functioning were associated positively with all perceptions of care, and comorbid schizophrenia, bipolar, and PTSD were associated positively with multiple perceptions of care. Perceived helpfulness of care was associated with receipt of SUD specialty care in the prior 12 months (adjusted OR = 1.77, p<.001). Controlling for patient characteristics, satisfaction with care exhibited strong associations with perceptions of staff as supportive and empathic, whereas perceived improvement was strongly linked to the perception that staff helped patients develop goals beyond symptom management. Survey responses that account for variation in SUD patients' perceptions of care could inform and guide quality improvement efforts with this population.

  7. Oral administration of soluble guanylate cyclase agonists to rats results in osteoclastic bone resorption and remodeling with new bone formation in the appendicular and axial skeleton.

    PubMed

    Homer, Bruce L; Morton, Daniel; Bagi, Cedo M; Warneke, James A; Andresen, Catharine J; Whiteley, Laurence O; Morris, Dale L; Tones, Michael A

    2015-04-01

    Orally administered small molecule agonists of soluble guanylate cyclase (sGC) induced increased numbers of osteoclasts, multifocal bone resorption, increased porosity, and new bone formation in the appendicular and axial skeleton of Sprague-Dawley rats. Similar histopathological bone changes were observed in both young (7- to 9-week-old) and aged (42- to 46-week-old) rats when dosed by oral gavage with 3 different heme-dependent sGC agonist (sGCa) compounds or 1 structurally distinct heme-independent sGCa compound. In a 7-day time course study in 7- to 9-week-old rats, bone changes were observed as early as 2 to 3 days following once daily compound administration. Bone changes were mostly reversed following a 14-day recovery period, with complete reversal after 35 days. The mechanism responsible for the bone changes was investigated in the thyroparathyroidectomized rat model that creates a low state of bone modeling and remodeling due to deprivation of thyroid hormone, calcitonin (CT), and parathyroid hormone (PTH). The sGCa compounds tested increased both bone resorption and formation, thereby increasing bone remodeling independent of calciotropic hormones PTH and CT. Based on these studies, we conclude that the bone changes in rats were likely caused by increased sGC activity.

  8. Evaluation of Administrators.

    ERIC Educational Resources Information Center

    Ryan, Edmund G.

    1979-01-01

    Guidelines are presented for the evaluation of college administrators: (1) purposes of the evaluation; (2) approaches to evaluation; (3) criteria for evaluation; (4) participants or evaluators in the process; and (5) evaluation results and use of results. (GDC)

  9. A Study of the Utility of Results from the 1992 Trial State Assessment (TSA) in Reading for State-Level Administrators of Assessment.

    ERIC Educational Resources Information Center

    Bullock, Cheryl Davis; DeStefano, Lizanne

    1998-01-01

    The usefulness of the 1992 TSA in reading was studied using interviews from 26 state directors of assessment. Perceptions about TSA credibility and orientation of test components and current use of TSA results were examined. The directors suggested involving more teachers in assessment, modifying descriptors, disseminating results quicker, and…

  10. Identifying tier one key suppliers.

    PubMed

    Wicks, Steve

    2013-01-01

    In today's global marketplace, businesses are becoming increasingly reliant on suppliers for the provision of key processes, activities, products and services in support of their strategic business goals. The result is that now, more than ever, the failure of a key supplier has potential to damage reputation, productivity, compliance and financial performance seriously. Yet despite this, there is no recognised standard or guidance for identifying a tier one key supplier base and, up to now, there has been little or no research on how to do so effectively. This paper outlines the key findings of a BCI-sponsored research project to investigate good practice in identifying tier one key suppliers, and suggests a scalable framework process model and risk matrix tool to help businesses effectively identify their tier one key supplier base. PMID:23615061

  11. Identifying tier one key suppliers.

    PubMed

    Wicks, Steve

    2013-01-01

    In today's global marketplace, businesses are becoming increasingly reliant on suppliers for the provision of key processes, activities, products and services in support of their strategic business goals. The result is that now, more than ever, the failure of a key supplier has potential to damage reputation, productivity, compliance and financial performance seriously. Yet despite this, there is no recognised standard or guidance for identifying a tier one key supplier base and, up to now, there has been little or no research on how to do so effectively. This paper outlines the key findings of a BCI-sponsored research project to investigate good practice in identifying tier one key suppliers, and suggests a scalable framework process model and risk matrix tool to help businesses effectively identify their tier one key supplier base.

  12. Administrative IT

    ERIC Educational Resources Information Center

    Grayson, Katherine, Ed.

    2006-01-01

    When it comes to Administrative IT solutions and processes, best practices range across the spectrum. Enterprise resource planning (ERP), student information systems (SIS), and tech support are prominent and continuing areas of focus. But widespread change can also be accomplished via the implementation of campuswide document imaging and sharing,…

  13. Database Administrator

    ERIC Educational Resources Information Center

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  14. ADMINISTRATIVE CLIMATE.

    ERIC Educational Resources Information Center

    BRUCE, ROBERT L.; CARTER, G.L., JR.

    IN THE COOPERATIVE EXTENSION SERVICE, STYLES OF LEADERSHIP PROFOUNDLY AFFECT THE QUALITY OF THE SERVICE RENDERED. ACCORDINGLY, MAJOR INFLUENCES ON ADMINISTRATIVE CLIMATE AND EMPLOYEE PRODUCTIVITY ARE EXAMINED IN ESSAYS ON (1) SOURCES OF JOB SATISFACTION AND DISSATISFACTION, (2) MOTIVATIONAL THEORIES BASED ON JOB-RELATED SATISFACTIONS AND NEEDS,…

  15. Engineering Administration.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    This book is intended to acquaint naval engineering officers with their duties in the engineering department. Standard shipboard organizations are analyzed in connection with personnel assignments, division operations, and watch systems. Detailed descriptions are included for the administration of directives, ship's bills, damage control, training…

  16. NASA fills key positions

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    NASA Administrator Sean O'Keefe has named Shannon Lucid, a NASA astronaut and veteran of five Space Shuttle flights, to serve as the agency's chief scientist. Lucid replaces Kathie Olsen, whom President Bush has said he intends to nominate as associate administrator for science in the White Office of Science and Technology Policy.President Bush also has announced his intention to nominate former NASA astronaut and Assistant Deputy Administrator Major General Charles F. Bolden as NASA Deputy Administrator.

  17. Patience: A Key Word when Talking with Teachers and Administrators

    ERIC Educational Resources Information Center

    McGee, Christy D.

    2012-01-01

    Summer activities have grown old. Going swimming has lost its allure, and boredom has set in. No matter how well parents have planned interesting and educational activities for the summer months or how much they have enjoyed the freedom from stricter schedules and more rigid bedtimes, it is time to transition back to the routines of the school…

  18. 75 FR 20364 - Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES ADMINISTRATION Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property..., identified as Key Largo Beacon Annex Site, Key Largo, FL to the U.S. Fish and Wildlife Service, Department...

  19. Results from the National Aeronautics and Space Administration remote sensing experiments in the New York Bight, 7-17 April 1975

    NASA Technical Reports Server (NTRS)

    Hall, J. B., Jr. (Compiler); Pearson, A. O. (Compiler)

    1977-01-01

    A cooperative operation was conducted in the New York Bight to evaluate the role of remote sensing technology to monitor ocean dumping. Six NASA remote sensing experiments were flown on the C-54, U-2, and C-130 NASA aircraft, while NOAA obtained concurrent sea truth information using helicopters and surface platforms. The experiments included: (1) a Radiometer/Scatterometer (RADSCAT), (2) an Ocean Color Scanner (OCS), (3) a Multichannel Ocean Color Sensor (MOCS), (4) four Hasselblad cameras, (5) an Ebert spectrometer; and (6) a Reconafax IV infrared scanner and a Precision Radiation Thermometer (PRT-5). The results of these experiments relative to the use of remote sensors to detect, quantify, and determine the dispersion of pollutants dumped into the New York Bight are presented.

  20. High frequency transcutaneous electrical nerve stimulation with diphenidol administration results in an additive antiallodynic effect in rats following chronic constriction injury.

    PubMed

    Lin, Heng-Teng; Chiu, Chong-Chi; Wang, Jhi-Joung; Hung, Ching-Hsia; Chen, Yu-Wen

    2015-03-01

    The impact of coadministration of transcutaneous electrical nerve stimulation (TENS) and diphenidol is not well established. Here we estimated the effects of diphenidol in combination with TENS on mechanical allodynia and tumor necrosis factor-α (TNF-α) expression. Using an animal chronic constriction injury (CCI) model, the rat was estimated for evidence of mechanical sensitivity via von Frey hair stimulation and TNF-α expression in the sciatic nerve using the ELISA assay. High frequency (100Hz) TENS or intraperitoneal injection of diphenidol (2.0μmol/kg) was applied daily, starting on postoperative day 1 (POD1) and lasting for the next 13 days. We demonstrated that both high frequency TENS and diphenidol groups had an increase in mechanical withdrawal thresholds of 60%. Coadministration of high frequency TENS and diphenidol gives better results of paw withdrawal thresholds in comparison with high frequency TENS alone or diphenidol alone. Both diphenidol and coadministration of high frequency TENS with diphenidol groups showed a significant reduction of the TNF-α level compared with the CCI or HFS group (P<0.05) in the sciatic nerve on POD7, whereas the CCI or high frequency TENS group exhibited a higher TNF-α level than the sham group (P<0.05). Our resulting data revealed that diphenidol alone, high frequency TENS alone, and the combination produced a reduction of neuropathic allodynia. Both diphenidol and the combination of diphenidol with high frequency TENS inhibited TNF-α expression. A moderately effective dose of diphenidol appeared to have an additive effect with high frequency TENS. Therefore, multidisciplinary treatments could be considered for this kind of mechanical allodynia. PMID:25596445

  1. Group key management

    SciTech Connect

    Dunigan, T.; Cao, C.

    1997-08-01

    This report describes an architecture and implementation for doing group key management over a data communications network. The architecture describes a protocol for establishing a shared encryption key among an authenticated and authorized collection of network entities. Group access requires one or more authorization certificates. The implementation includes a simple public key and certificate infrastructure. Multicast is used for some of the key management messages. An application programming interface multiplexes key management and user application messages. An implementation using the new IP security protocols is postulated. The architecture is compared with other group key management proposals, and the performance and the limitations of the implementation are described.

  2. Sustaining Control of Schistosomiasis Mansoni in Western Côte d’Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration

    PubMed Central

    Assaré, Rufin K.; Tian-Bi, Yves-Nathan T.; Yao, Patrick K.; N’Guessan, Nicaise A.; Ouattara, Mamadou; Yapi, Ahoua; Coulibaly, Jean T.; Meïté, Aboulaye; Hürlimann, Eveline; Knopp, Stefanie; Utzinger, Jürg; N’Goran, Eliézer K.

    2016-01-01

    Background The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) has launched several large-scale trials to determine the best strategies for gaining and sustaining control of schistosomiasis and transitioning toward elimination. In Côte d’Ivoire, a 5-year cluster-randomized trial is being implemented in 75 schools to sustain the control of schistosomiasis mansoni. We report Schistosoma mansoni infection levels in children one year after the initial school-based treatment (SBT) with praziquantel and compare with baseline results to determine the effect of the intervention. Methodology The baseline cross-sectional survey was conducted in late 2011/early 2012 and the first follow-up in May 2013. Three consecutive stool samples were collected from 9- to 12-year-old children in 75 schools at baseline and 50 schools at follow-up. Stool samples were subjected to duplicate Kato-Katz thick smears. Directly observed treatment (DOT) coverage of the SBT was assessed and the prevalence and intensity of S. mansoni infection compared between baseline and follow-up. Principal Findings The S. mansoni prevalence in the 75 schools surveyed at baseline was 22.1% (95% confidence interval (CI): 19.5–24.4%). The DOT coverage was 84.2%. In the 50 schools surveyed at baseline and one year after treatment, the overall prevalence of S. mansoni infection decreased significantly from 19.7% (95% CI: 18.5–20.8%) to 12.8% (95% CI: 11.9–13.8%), while the arithmetic mean S. mansoni eggs per gram of stool (EPG) among infected children slightly increased from 92.2 EPG (95% CI: 79.2–105.3 EPG) to 109.3 EPG (95% CI: 82.7–135.9 EPG). In two of the 50 schools, the prevalence increased significantly, despite a DOT coverage of >75%. Conclusions/Significance One year after the initial SBT, the S. mansoni prevalence had decreased. Despite this positive trend, an increase was observed in some schools. Moreover, the infection intensity among S. mansoni-infected children

  3. Evaluation of the Effects of Pasireotide LAR Administration on Lymphocele Prevention after Axillary Node Dissection for Breast Cancer: Results of a Randomized Non-Comparative Phase 2 Study

    PubMed Central

    Chéreau, Elisabeth; Uzan, Catherine; Boutmy-Deslandes, Emmanuelle; Zohar, Sarah; Bézu, Corinne; Mazouni, Chafika; Garbay, Jean-Rémi; Daraï, Emile; Rouzier, Roman

    2016-01-01

    Objective The aim of this study was to assess the efficacy (response rate centered on 80%) of a somatostatin analog with high affinity for 4 somatostatin receptors in reducing the postoperative incidence of symptomatic lymphocele formation following total mastectomy with axillary lymph node dissection. Setting This prospective, double-blind, randomised, placebo-controlled, phase 2 trial was conducted in two secondary care centres. Participants All female patients for whom mastectomy and axillary lymph node dissection were indicated were eligible for the study, including patients who had received neo-adjuvant chemotherapy. Main exclusion criteria were related to diabetes, cardiac insufficiency, disorder of cardiac conduction or hepatic failure. Interventions Patients were randomised to receive one injection of either prolonged-release pasireotide 60 mg or placebo (physiological serum), which were administered intramuscularly 7 to 10 days before the scheduled surgery. The study was conducted in a double-blind manner. Primary and Secondary Outcome Measures The primary outcome measure was the percentage of patients who did not develop post-operative axillary symptomatic lymphoceles during the 2 postoperative months. Secondary endpoints were the total quantity of lymph drained, duration and daily volume of drainage and aspirated volumes of lymph. Results Ninety-one patients were randomised. Ninety patients were evaluable: 42 patients received pasireotide, and 48 patients received placebo. The mean estimated response rate were 62.4% (95% Credibility Interval [CrI]: 48.6%-75.3%) in the treatment group and 50.2% (95% CrI: 37.6%-62.8%) in the placebo group. Overall safety was comparable across groups, and one serious adverse event occurred. In the treatment group, one patient with known insulin-depe*ndent diabetes required hospitalization for hyperglycaemia. Conclusions With this phase 2 preliminary study, even if our results indicate a trend towards a reduction in

  4. Chronic administration of dexamethasone results in Fc receptor up-regulation and inhibition of class I antigen expression on macrophages from MRL/lpr autoimmune mice.

    PubMed Central

    Zuckerman, S H; Evans, G F; Bryan, N

    1997-01-01

    The MRL/lpr mouse develops, after approximately 8 weeks of age, a severe autoimmune syndrome with many features resembling human systemic lupus erythematosus, including autoantibodies against DNA and basement membranes resulting in immune complexes, vasculitis, and multiorgan disease. While this murine model of lupus has been used for the identification of therapeutics with potential efficacy in human autoimmune disease, the long-term impact of chronic immunosuppressive therapy on macrophage function in this paradigm is not understood. To this end, MRL/lpr mice were treated prophylactically with dexamethasone at 0.01, 0.1, and 1 mg/kg of body weight for 20 weeks or were allowed to develop autoimmune disease and, at 15 weeks of age, treated therapeutically with 1-mg/kg dexamethasone for 8 additional weeks. Analysis of surface antigens on resident peritoneal macrophages demonstrated a progressive loss in class I expression with a concomitant increase in Fc receptor expression. Neither phagocytosis nor CD11b expression was modulated with chronic steroid treatment. Furthermore, dexamethasone treatment was associated with a reduction in anti-DNA antibodies and total immunoglobulin G and yet an elevation in serum cholesterol due to an increase in high-density lipoproteins. Therefore, the MRL/lpr mouse serves not only as a small-animal model of autoimmune disease but also as one in which the negative and positive sequelae associated with chronic immunosuppression can be further understood. PMID:9302207

  5. Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart

    PubMed Central

    Aravindhan, Karpagam; Bao, Weike; Harpel, Mark R.; Willette, Robert N.; Lepore, John J.; Jucker, Beat M.

    2015-01-01

    Previous studies have shown that glucagon-like peptide-1 (GLP-1) provides cardiovascular benefits independent of its role on peripheral glycemic control. However, the precise mechanism(s) by which GLP-1 treatment renders cardioprotection during myocardial ischemia remain unresolved. Here we examined the role for GLP-1 treatment on glucose and fatty acid metabolism in normal and ischemic rat hearts following a 30 min ischemia and 24 h reperfusion injury, and in isolated cardiomyocytes (CM). Relative carbohydrate and fat oxidation levels were measured in both normal and ischemic hearts using a 1-13C glucose clamp coupled with NMR-based isotopomer analysis, as well as in adult rat CMs by monitoring pH and O2 consumption in the presence of glucose or palmitate. In normal heart, GLP-1 increased glucose uptake (↑64%, p<0.05) without affecting glycogen levels. In ischemic hearts, GLP-1 induced metabolic substrate switching by increasing the ratio of carbohydrate versus fat oxidation (↑14%, p<0.01) in the LV area not at risk, without affecting cAMP levels. Interestingly, no substrate switching occurred in the LV area at risk, despite an increase in cAMP (↑106%, p<0.05) and lactate (↑121%, p<0.01) levels. Furthermore, in isolated CMs GLP-1 treatment increased glucose utilization (↑14%, p<0.05) and decreased fatty acid oxidation (↓15%, p<0.05) consistent with in vivo finding. Our results show that this benefit may derive from distinct and complementary roles of GLP-1 treatment on metabolism in myocardial sub-regions in response to this injury. In particular, a switch to anaerobic glycolysis in the ischemic area provides a compensatory substrate switch to overcome the energetic deficit in this region in the face of reduced tissue oxygenation, whereas a switch to more energetically favorable carbohydrate oxidation in more highly oxygenated remote regions supports maintaining cardiac contractility in a complementary manner. PMID:26098939

  6. Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart.

    PubMed

    Aravindhan, Karpagam; Bao, Weike; Harpel, Mark R; Willette, Robert N; Lepore, John J; Jucker, Beat M

    2015-01-01

    Previous studies have shown that glucagon-like peptide-1 (GLP-1) provides cardiovascular benefits independent of its role on peripheral glycemic control. However, the precise mechanism(s) by which GLP-1 treatment renders cardioprotection during myocardial ischemia remain unresolved. Here we examined the role for GLP-1 treatment on glucose and fatty acid metabolism in normal and ischemic rat hearts following a 30 min ischemia and 24 h reperfusion injury, and in isolated cardiomyocytes (CM). Relative carbohydrate and fat oxidation levels were measured in both normal and ischemic hearts using a 1-13C glucose clamp coupled with NMR-based isotopomer analysis, as well as in adult rat CMs by monitoring pH and O2 consumption in the presence of glucose or palmitate. In normal heart, GLP-1 increased glucose uptake (↑64%, p<0.05) without affecting glycogen levels. In ischemic hearts, GLP-1 induced metabolic substrate switching by increasing the ratio of carbohydrate versus fat oxidation (↑14%, p<0.01) in the LV area not at risk, without affecting cAMP levels. Interestingly, no substrate switching occurred in the LV area at risk, despite an increase in cAMP (↑106%, p<0.05) and lactate (↑121%, p<0.01) levels. Furthermore, in isolated CMs GLP-1 treatment increased glucose utilization (↑14%, p<0.05) and decreased fatty acid oxidation (↓15%, p<0.05) consistent with in vivo finding. Our results show that this benefit may derive from distinct and complementary roles of GLP-1 treatment on metabolism in myocardial sub-regions in response to this injury. In particular, a switch to anaerobic glycolysis in the ischemic area provides a compensatory substrate switch to overcome the energetic deficit in this region in the face of reduced tissue oxygenation, whereas a switch to more energetically favorable carbohydrate oxidation in more highly oxygenated remote regions supports maintaining cardiac contractility in a complementary manner.

  7. The effect of acute simvastatin administration on the severity of arrhythmias resulting from ischaemia and reperfusion in the canine: Is there a role for nitric oxide?

    PubMed

    Kisvári, Gábor; Kovács, Mária; Gardi, János; Seprényi, György; Kaszaki, József; Végh, Ágnes

    2014-06-01

    The present study has examined the effects and the possible mechanisms of a single dose of simvastatin on the severity of arrhythmias resulting from a 25min occlusion and reperfusion of the left anterior descending coronary artery in anaesthetized (chloralose and urethane) dogs. The control animals (n=16) were given the solvent of simvastatin by slow (over 5min) intracoronary (ic.) injection just prior to the occlusion. Twenty-six dogs were treated with simvastatin (0.1mg/kg) by the same route, both in the absence (n=15) and in the presence (n=11) of l-NAME. This latter was administered (5mg/kg, ic.) either alone (n=12) or 10min before the simvastatin treatment. The severity of ischaemia (epicardial ST-segment, inhomogeneity) and ventricular arrhythmias (ventricular premature beats [VPBs], ventricular tachycardia [VT] and fibrillation [VF]), plasma nitrite/nitrate levels, myocardial superoxide production and eNOS activity were assessed. Compared with controls simvastatin significantly reduced the number of VPBs (289±34vs. 94±25) and the episodes of VT (5.6±1.3vs. 0.3±0.2), the incidence of VT (88% vs. 20%) and VF (56% vs. 0%) during occlusion and increased survival (0% vs. 33%) on reperfusion. There were also less marked ischaemic changes in the simvastatin-treated dogs than in the controls. Simvastatin preserved eNOS activity and nitric oxide (NO) bioavailability during occlusion and attenuated superoxide production following reperfusion. All these effects of simvastatin (except for the protection against VF) were reversed by l-NAME. We conclude that simvastatin given just prior to ischaemia/reperfusion reduces the severity of arrhythmias. This effect involves both NO-dependent and NO-independent mechanisms. PMID:24685640

  8. Training and administration of epinephrine auto-injectors for anaphylaxis treatment in US schools: results from the EpiPen4Schools® pilot survey

    PubMed Central

    Hogue, Susan L; Goss, Diana; Hollis, Kelly; Silvia, Suyapa; White, Martha V

    2016-01-01

    Background Anaphylaxis is a serious, potentially life-threatening condition. Adequate preparation for anaphylaxis management is imperative for school personnel. This descriptive pilot study assessed preparedness of US schools to manage anaphylactic reactions. Methods An exploratory, cross-sectional, web-based, pilot survey assessed the occurrence and characteristics of anaphylactic events, as well as training provided to school personnel for the recognition and treatment of anaphylaxis. Eligible US schools were participants in the EpiPen4Schools® program during the 2013–2014 school year. EpiPen4Schools provides EpiPen® (epinephrine injection) Auto-Injectors and training materials to qualifying US schools. Survey data were parsed by US Census Bureau region and state and were evaluated using descriptive statistics. Results Schools from all 50 states and the District of Columbia participated in the survey (N=6,019). Among schools that provided information on anaphylactic events, 11% (607/5,683) reported the occurrence of one or more events, with significant variability in incidence across census regions and among states. A total of 5,613 schools provided information regarding which staff members were trained to recognize the signs and symptoms of anaphylaxis. Thirty-six percent of schools (2,022/5,613) indicated that only the school nurse and select staff were trained in anaphylaxis recognition. The proportion of schools in which most or all school staff received such training differed by region/state (range, 13%–100%). A total of 5,578 schools provided information on which staff were permitted to administer epinephrine. The majority of schools (54%; 3,024/5,578) permitted only the school nurse and select staff to administer epinephrine, although percentages varied by region/state (range, 4%–100%). Conclusion Schools differed substantially in their preparedness to manage anaphylaxis, with significant disparities in staff training and permission to treat. Given

  9. Public Key Cryptography.

    ERIC Educational Resources Information Center

    Tapson, Frank

    1996-01-01

    Describes public key cryptography, also known as RSA, which is a system using two keys, one used to put a message into cipher and another used to decipher the message. Presents examples using small prime numbers. (MKR)

  10. Novice Administrators: Psychological and Physiological Effects.

    ERIC Educational Resources Information Center

    Schmidt, Linda J.; Kosmoski, Georgia J.; Pollack, Dennis R.

    Novice school administrators find that demands for excellence have grown while budgets have shrunk. This paper reports on a study that examined the stress levels of beginning administrators. Two of the key questions for the study--Is the stress experienced by new school administrators manageable or out of control? and Does the job put beginning…

  11. Inhibition of ovulation by administration of estetrol in combination with drospirenone or levonorgestrel: Results of a phase II dose-finding pilot study

    PubMed Central

    Duijkers, Ingrid J.M.; Klipping, Christine; Zimmerman, Yvette; Appels, Nicole; Jost, Maud; Maillard, Catherine; Mawet, Marie; Foidart, Jean-Michel; Coelingh Bennink, Herjan J. T.

    2015-01-01

    Abstract Objectives The aim of the study was to evaluate the efficacy of different dosages of estetrol (E4) combined with one of two progestins in suppressing the pituitary–ovarian axis and ovulation in healthy premenopausal women. Methods This was an open, parallel, phase II, dose-finding, pilot study performed in healthy women aged 18 to 35 years with a documented ovulatory cycle before treatment. For three consecutive cycles in a 24/4-day regimen, participants received 5 mg or 10 mg E4/3 mg drospirenone (DRSP); 5 mg, 10 mg or 20 mg E4/150 μg levonorgestrel; or 20 μg ethinylestradiol (EE)/3 mg DRSP as comparator. Pituitary–ovarian axis activity and the occurrence of ovulation were evaluated by monitoring follicular size, serum levels of follicle-stimulating hormone, luteinising hormone, estradiol and progesterone during treatment cycles 1 and 3. Endometrial thickness was evaluated throughout the trial, and the return of ovulation was evaluated after the last intake of medication. Results A total of 109 women were included in the trial. No ovulation occurred in any treatment group. Ovarian activity inhibition seemed proportional to the E4 dosage: the highest suppression was observed in the 20 mg E4 group and was very similar to that observed with EE/DRSP. Endometrial thickness was suppressed to the same extent in all groups. Post-treatment ovulation occurred in all participants between 17 and 21 days after the last active treatment. The study combinations were well tolerated and safe. Conclusions Combined with a progestin, E4 adequately suppresses ovarian activity, particularly when given at a dosage above 10 mg/day. Chinese Abstract 摘要 目的 这项研究的目的是评估不同剂量的雌四醇联合两种孕激素中的其中一种对垂体-卵巢轴以及健康的绝经前妇女的排卵方面的抑制疗效。 方法 这是一个在18到35岁的健康女性中进行的开放的、平行的,关于II期药物剂量探索的初步研究,这些女

  12. Keys to Scholarship

    ERIC Educational Resources Information Center

    Hebert, Terri

    2011-01-01

    Up ahead, a foreboding wooden door showing wear from passage of earlier travelers is spotted. As the old porch light emits a pale yellow glow, a key ring emerges from deep inside the coat pocket. Searching for just the right key, the voyager settles on one that also shows age. As the key enters its receptacle and begins to turn, a clicking noise…

  13. Work Keys USA.

    ERIC Educational Resources Information Center

    Work Keys USA, 1998

    1998-01-01

    "Work Keys" is a comprehensive program for assessing and teaching workplace skills. This serial "special issue" features 18 first-hand reports on Work Keys projects in action in states across North America. They show how the Work Keys is helping businesses and educators solve the challenge of building a world-class work force. The reports are as…

  14. Hospital administrators in a market environment: the case of Utah.

    PubMed

    Dwore, R B; Murray, B P

    1987-11-01

    This study describes selected characteristics of hospital administrators in Utah, who are implementing a market strategy of cost containment. A mail survey was used to query hospital administrators concerning their personal backgrounds, professional practice patterns, and perceived role performance. The questionnaire elicited a 75.6 percent return from a limited universe sample. Analytical results disclose that Utah hospital administrators are relatively young, professionally dynamic, well educated, and subject to frequent career-motivated moves. Using Mintzberg's ten administrative roles, respondents identified two as key: "Leader" ranks as the role performed best, the role second most critical to survival, second best prepared for, second most time-consuming, and second most satisfying. "Entrepreneur" ranks as the role most critical to survival, most satisfying, most deserving of improvement, second least prepared for, and second best performed. Suggestions for innovative ways in which administrators can develop their skills to be better prepared to meet future challenges are listed.

  15. Paediatric pharmacokinetics: key considerations

    PubMed Central

    Batchelor, Hannah Katharine; Marriott, John Francis

    2015-01-01

    A number of anatomical and physiological factors determine the pharmacokinetic profile of a drug. Differences in physiology in paediatric populations compared with adults can influence the concentration of drug within the plasma or tissue. Healthcare professionals need to be aware of anatomical and physiological changes that affect pharmacokinetic profiles of drugs to understand consequences of dose adjustments in infants and children. Pharmacokinetic clinical trials in children are complicated owing to the limitations on blood sample volumes and perception of pain in children resulting from blood sampling. There are alternative sampling techniques that can minimize the invasive nature of such trials. Population based models can also limit the sampling required from each individual by increasing the overall sample size to generate robust pharmacokinetic data. This review details key considerations in the design and development of paediatric pharmacokinetic clinical trials. PMID:25855821

  16. Key scientific findings and policy- and health-relevant insights from the U.S. Environmental Protection Agency's Particulate Matter Supersites Program and related studies: an integration and synthesis of results.

    PubMed

    Solomon, Paul A; Hopke, Philip K; Froines, John; Scheffe, Richard

    2008-01-01

    In 1998, the U.S. Environmental Protection Agency (EPA) initiated a major air quality program known as the Particulate Matter (PM) Supersites Program. The Supersites Program was a multiyear, $27 million air quality monitoring program consisting of eight regional air quality projects located throughout the United States, each with differing atmospheric pollution conditions resulting from variations in source emissions and meteorology. The overall goal of the program was to elucidate source-receptor relationships and atmospheric processes leading to PM accumulation on urban and regional scales; thus providing the scientific underpinning for modeling and data analysis efforts to support State Implementation Plans and more effective risk management approaches for PM. The program had three main objectives: (1) conduct methods development and evaluation, (2) characterize ambient PM, and (3) support health effects and exposure research. This paper provides a synthesis of key scientific findings from the Supersites Program and related studies. EPA developed 16 science/policy-relevant questions in conjunction with state and other federal agencies, Regional Planning Organizations, and the private sector. These questions were addressed to the extent possible, even given the vast amount of new information available from the Supersites Program, in a series of papers published as a special issue of the Journal of Air & Waste Management Association (February 2008). This synthesis also includes discussions of: (1) initial Supersites Program support for air quality management efforts in specific locations throughout the United States; (2) selected policy-relevant insights, based on atmospheric sciences findings, useful to air quality managers and decision makers planning emissions management strategies to address current and future PM National Ambient Air Quality Standards (NAAQS) and network planning and implementation; (3) selected health-relevant insights interpreted from

  17. State costs of implementing the 1986 Safe Drinking Water Act Amendments. Results and implications of the 1988 Association of State Drinking Water Administrators' survey of state primacy program resource needs

    SciTech Connect

    Not Available

    1989-07-20

    To assist the Office of Drinking Water in estimating the state costs of regulatory options and in providing guidance and assistance to state programs, the Survey of State Primacy Program Resource Needs was conducted in the summer and fall of 1988. The survey was a joint effort between EPA and the Association of State Drinking Water Administrators (ASDWA). A detailed 18 page questionnaire and a 38 page supplement were prepared to obtain from each state and territory an estimate of the staff and funding resources needed both to implement existing programs and to meet the new requirements. ASDWA distributed the survey to all states and territories and compiled the responses in a data base as they were received. EPA supported ASDWA in delineating the expected requirements, providing implementation schedules of the forthcoming rules, and analyzing the results of the survey. The report discusses the methodology used in developing and conducting the survey and presents the results of the analyses.

  18. Student Success Factors: Identifying Key Predictors

    ERIC Educational Resources Information Center

    Sulaiman, Ainin; Mohezar, Suhana

    2006-01-01

    The authors' main aim in this study was to identify key predictors of Master of Business Administration (MBA) students' academic performance. The authors measured performance by the students' cumulative grade point average achieved, using data from the Students Information Systems and Application database. The authors found that a student's…

  19. Key Stage 3 Pupils' Perception of Music

    ERIC Educational Resources Information Center

    Button, Stuart

    2006-01-01

    The key aim of the research summarised in this article was to examine pupils' perception of music and to determine whether or not these perceptions were the same for both female and male pupils. The empirical enquiry consisted of the administration of a questionnaire to six secondary schools in the north-east of England followed by semi-structured…

  20. The administration of a polyvalent mechanical bacterial lysate in elderly patients with COPD results in serological signs of an efficient immune response associated with a reduced number of acute episodes.

    PubMed

    Ricci, Rossella; Palmero, Candida; Bazurro, Gyada; Riccio, Anna Maria; Garelli, Valentina; Di Marco, Eddi; Cirillo, Carmelina; Braido, Fulvio; Canonica, Giorgio Walter; Melioli, Giovanni

    2014-02-01

    The administration of a polyvalent mechanical bacterial lysate (PMBL) in elderly patients with COPD has been shown to reduce the number of exacerbation. This is largely related to the involvement of cells belonging to the innate and the adaptive immune system (including dendritic cells, granulocytes, T and B lymphocytes and NK cells) that actively cooperate inducing the production of specific opsonizing antibodies directed to the antigens of PMBL. We have evaluated the production of antibodies directed to respiratory and systemic pathogens in a group of elderly COPD patients, recruited in a clinical trial, ancillary to a larger multicenter double blind, placebo-controlled, parallel-designed clinical trial in which patients were randomized to daily receive either PMBL or placebo. The treated group not only experienced a reduced number of seroconversion, but also, better controlled the number of infectious episodes and COPD exacerbations. It was thus evident that the administration of PMBL resulted not only effective in inducing the secretion of specific antibodies, but also effective in reducing the infectious episodes trough the potentiation of the antibody-mediated arm of the immune response. PMID:23792312

  1. Optical key system

    DOEpatents

    Hagans, Karla G.; Clough, Robert E.

    2000-01-01

    An optical key system comprises a battery-operated optical key and an isolated lock that derives both its operating power and unlock signals from the correct optical key. A light emitting diode or laser diode is included within the optical key and is connected to transmit a bit-serial password. The key user physically enters either the code-to-transmit directly, or an index to a pseudorandom number code, in the key. Such person identification numbers can be retained permanently, or ephemeral. When a send button is pressed, the key transmits a beam of light modulated with the password information. The modulated beam of light is received by a corresponding optical lock with a photovoltaic cell that produces enough power from the beam of light to operate a password-screen digital logic. In one application, an acceptable password allows a two watt power laser diode to pump ignition and timing information over a fiberoptic cable into a sealed engine compartment. The receipt of a good password allows the fuel pump, spark, and starter systems to each operate. Therefore, bypassing the lock mechanism as is now routine with automobile thieves is pointless because the engine is so thoroughly disabled.

  2. Optimizing Requirements Decisions with KEYS

    NASA Technical Reports Server (NTRS)

    Jalali, Omid; Menzies, Tim; Feather, Martin

    2008-01-01

    Recent work with NASA's Jet Propulsion Laboratory has allowed for external access to five of JPL's real-world requirements models, anonymized to conceal proprietary information, but retaining their computational nature. Experimentation with these models, reported herein, demonstrates a dramatic speedup in the computations performed on them. These models have a well defined goal: select mitigations that retire risks which, in turn, increases the number of attainable requirements. Such a non-linear optimization is a well-studied problem. However identification of not only (a) the optimal solution(s) but also (b) the key factors leading to them is less well studied. Our technique, called KEYS, shows a rapid way of simultaneously identifying the solutions and their key factors. KEYS improves on prior work by several orders of magnitude. Prior experiments with simulated annealing or treatment learning took tens of minutes to hours to terminate. KEYS runs much faster than that; e.g for one model, KEYS ran 13,000 times faster than treatment learning (40 minutes versus 0.18 seconds). Processing these JPL models is a non-linear optimization problem: the fewest mitigations must be selected while achieving the most requirements. Non-linear optimization is a well studied problem. With this paper, we challenge other members of the PROMISE community to improve on our results with other techniques.

  3. An Alternative to Keys

    ERIC Educational Resources Information Center

    O'Hagan, James

    1977-01-01

    For the secondary school, the author discourages the use of dichotomous keys in favor of a punch-card system. The system is readily constructed by students for use in plant and animal classification. (CP)

  4. Public Key FPGA Software

    SciTech Connect

    Hymel, Ross

    2013-07-25

    The Public Key (PK) FPGA software performs asymmetric authentication using the 163-bit Elliptic Curve Digital Signature Algorithm (ECDSA) on an embedded FPGA platform. A digital signature is created on user-supplied data, and communication with a host system is performed via a Serial Peripheral Interface (SPI) bus. Software includes all components necessary for signing, including custom random number generator for key creation and SHA-256 for data hashing.

  5. Security of Quantum Key Distribution

    NASA Astrophysics Data System (ADS)

    Lütkenhaus, Norbert

    2007-03-01

    Quantum Key Distribution (QKD) is the most advanced application of Quantum Information Science. It allows extending secret keys over some distances in such a way that the security of the resulting key material can be guaranteed by the laws of quantum mechanics. In contrast to presently used encryption techniques, the security of QKD can be proven in terms of information-theoretic measures. The resulting key can then be used for many tasks, including exchanging secret messages. QKD has been developed in the language of abstract two-level systems, the qubits. They cannot be easily implemented in optical signals. It took some time to bring the protocols and theory of QKD to the point where they fit to the realities of fiber-optical or free-space applications, including lossy channels. Today, QKD schemes can be implemented reliably using standard off-the-shelf components. Information theoretic security is a theoretical concept. Naturally, it is impossible to demonstrate directly that a given experimental set-up indeed creates a secret key. What one can do is to show that the experiment can give data within a certain parameters regime, such as error rate and loss rate, for which a security proof exists. I will discuss what parameter regime gives provable secure key and which parameter regime cannot lead to secret key. It is desirable to prove `unconditional security,' as it is termed in the world of classical cryptography: no assumption is made about the attacks of an eavesdropper on the quantum channel. However, one has to assume that the signal structure and the measurement device are correctly described by the adopted model and that no eavesdropper can intrude the sender or receiver unit. In this talk I will briefly introduce the concept of QKD and optical implementations. Especially I will discuss security aspects of modern approaches of QKD schemes that allow us to increase the covered distance and the achievable rate.

  6. Opportunities for administrators to promote disease management.

    PubMed

    Kash, Bita A; Gamm, Larry D; Bolin, Jane Nelson; Peck, B Mitchell

    2005-01-01

    Studies of disease management (DM) have shown that patients who participate in such programs achieve better health status and make fewer emergency room visits. Private and government payers have recently increased their efforts to promote DM initiatives through financial incentives to healthcare providers. This article explores opportunities for administrators of health services organizations (HSO) to promote DM in the current political and economic environment. Our survey of professionals (DM leaders, physicians, and DM nurses) in six DM programs reveals these professionals' assessments of the key players and resources that they deem important to their respective DM programs. They view DM programs as heavily dependent on the support of physicians, nurses, and health plan leaders but relatively less so on the support of HSO administrators- a situation that may suggest opportunities for administrators to take on greater leadership in moving the HSO toward developing DM programs. Survey results also indicate a strong need for the integration of resources such as communication systems, electronic medical records, and DM reporting. Taken collectively, these needs suggest a number of strategies for the administrator to play a larger role in supporting the adoption and effective implementation of DM. In the article, we propose that DM programs can benefit substantially from an administrator who can demonstrate a thorough knowledge of DM-related government and private-payer initiatives and who has the ability to provide leadership to develop and implement viable DM programs. Valued contributions that the administrator should bring to the table include support of standardized DM processes, use of practice guidelines, and provision of pertinent information systems.

  7. Progress and goals for INMM ASC N15 consensus standard ""Administrative practices for the determination and reporting of results of non-destructive assay measurements of nuclear material in situ for safeguards nuclear criticality safety and other purposes

    SciTech Connect

    Bracken, David S; Lamb, Frank W

    2009-01-01

    This paper will discuss the goals and progress to date on the development of INMM Accredited Standard Committee (ASC) N15 consensus standard Administrative Practices for the Determination and Reporting of Results of Non-Destructive Assay Measurements of Nuclear Material in situ for Safeguards, Nuclear Criticality Safety, and Other Purposes. This standard will define administrative practices in the areas of data generation and reporting of NDA assay of holdup deposits with consideration of the stakeholders of the reported results. These stakeholders may include nuclear material accounting and safeguards, nuclear criticality safety, waste management, health physics, facility characterization, authorization basis, radiation safety, and site licensing authorities. Stakeholder input will be solicited from interested parties and incorporated during the development of the document. Currently only one consensus standard exists that explicitly deals with NDA holdup measurements: ASTM C1455 Standard Test Method for Nondestructive Assay of Special Nuclear Material Holdup Using Gamma-Ray Spectroscopic Methods. The ASTM International standard emphasizes the activities involved in actually making measurements, and was developed by safeguards and NDA experts. This new INMM ASC N15 standard will complement the existing ASTM international standard. One of the largest driving factors for writing this new standard was the recent emphasis on in situ NDA measurements by the safeguards community due to the Defense Nuclear Facility Safety Board (DNFSB) recommendation 2007-1 on in situ NDA measurements. Specifically, DNFSB recommendation 2007-1 referenced the lack of programmatic requirements for accurate in situ measurements and the use of measurement results for compliance with safety based requirements. That being the case, this paper will also discuss the progress made on the Implementation Plan for Defense Nuclear Facilities Safety Board Recommendation 2007-1 Safety-Related In Situ

  8. What Makes a Good Music Administrator?

    ERIC Educational Resources Information Center

    Cowden, Robert L.

    1984-01-01

    The key to the successful college level music administrator is the ability to deal with people. S/he listens, is accessible, and can make decisions. Both autocratic and democratic personality types can succeed, and their levels of experience may vary, but good administrators must have vision. (CS)

  9. Driver Education Program. Administrative and Curriculum Guide.

    ERIC Educational Resources Information Center

    Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

    This administrative and curriculum guide is designed for use in establishing and teaching a driver education course for high school students. The first section of the guide, a discussion of program administration, deals with various aspects of program management as well as the roles and responsibilities of the key practitioners involved in driver…

  10. Decoy State Quantum Key Distribution

    NASA Astrophysics Data System (ADS)

    Lo, Hoi-Kwong

    2005-10-01

    Quantum key distribution (QKD) allows two parties to communicate in absolute security based on the fundamental laws of physics. Up till now, it is widely believed that unconditionally secure QKD based on standard Bennett-Brassard (BB84) protocol is limited in both key generation rate and distance because of imperfect devices. Here, we solve these two problems directly by presenting new protocols that are feasible with only current technology. Surprisingly, our new protocols can make fiber-based QKD unconditionally secure at distances over 100km (for some experiments, such as GYS) and increase the key generation rate from O(η2) in prior art to O(η) where η is the overall transmittance. Our method is to develop the decoy state idea (first proposed by W.-Y. Hwang in "Quantum Key Distribution with High Loss: Toward Global Secure Communication", Phys. Rev. Lett. 91, 057901 (2003)) and consider simple extensions of the BB84 protocol. This part of work is published in "Decoy State Quantum Key Distribution", . We present a general theory of the decoy state protocol and propose a decoy method based on only one signal state and two decoy states. We perform optimization on the choice of intensities of the signal state and the two decoy states. Our result shows that a decoy state protocol with only two types of decoy states--a vacuum and a weak decoy state--asymptotically approaches the theoretical limit of the most general type of decoy state protocols (with an infinite number of decoy states). We also present a one-decoy-state protocol as a special case of Vacuum+Weak decoy method. Moreover, we provide estimations on the effects of statistical fluctuations and suggest that, even for long distance (larger than 100km) QKD, our two-decoy-state protocol can be implemented with only a few hours of experimental data. In conclusion, decoy state quantum key distribution is highly practical. This part of work is

  11. 77 FR 38273 - Availability of Seats for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... National Oceanic and Atmospheric Administration Availability of Seats for the Florida Keys National Marine... Florida Keys National Marine Sanctuary Advisory Council: Citizen at Large--Lower Keys (alternate), Citizen at Large--Middle Keys (member), Citizen at Large--Middle Keys (alternate), Conservation...

  12. Postmodernism in Higher Educational Administration

    ERIC Educational Resources Information Center

    Demaris, Michalyn C.; Kritsonis, William Allan

    2007-01-01

    Postmodernism has many inferences that can be applied to the theory and practice of higher educational administration. Today, in higher education administrators are continuously focused on strategies that will ensure the future of minority educational institutions. As a result postmodernism is an important factor in the future of higher…

  13. Identification of Key Barriers in Workforce Development

    SciTech Connect

    2008-03-31

    This report documents the identification of key barriers in the development of an adequate national security workforce as part of the National Security Preparedness Project, being performed under a Department of Energy/National Nuclear Security Administration grant. Many barriers exist that prevent the development of an adequate number of propertly trained national security personnel. Some barriers can be eliminated in a short-term manner, whereas others will involve a long-term strategy that takes into account public policy.

  14. Why do key integrated delivery stakeholders really matter? Assessing control, coalitions, resources and power.

    PubMed

    Dymond, S; Nix, T W; Rotarius, T M; Savage, G T

    1995-01-01

    This is the fourth in a series of articles describing and interpreting the results from the Facing the Uncertain Future (FUF) study. This article focuses on one vital aspect of strategic stakeholder management: assessment of key stakeholders. Specifically, the article uses Round Two data and presents an assessment of four key medical group practice stakeholders: integrated delivery systems/networks (IDS/Ns), managed care organizations (MCOs), physicians and hospitals. These key stakeholders were identified by medical group practice executives as some of the most important stakeholders in the year 2000. These four stakeholders are assessed on the criteria of organizational control, coalition formation, control of resources, and relative power. The FUF study was conducted jointly between the Center for Research in Ambulatory Health Care Administration (the research and development arm of MGMA), and The Institute for Management and Leadership Research (IMLR), College of Business Administration at Texas Tech University, Lubbock, Texas. MGMA's American College of Medical Practice Executives, faculty of Texas Tech University's Ph.D. and M.B.A. Programs in Health Organization Management (HOM), and faculty from the University of Alabama at Birmingham collaborated on the project. Abbott Laboratories, Abbott Park, Ill., provided funding for the FUF project. The administration of Round One was completed in the Fall of 1994. The administration of Round Two was completed in the summer of 1995. Selected Round One and Round Two results have previously been presented in educational programs and publications.

  15. Key Process Benchmarking for Continuous Improvement in Higher Education.

    ERIC Educational Resources Information Center

    Stewart, Robert Grisham

    The objectives of this study were identification and verification of key processes that could be used by higher education quality administrators to implement continuous improvement programs and benchmarking processes. East Tennessee State University's Continuous Improvement Key Process Relationship Matrix was used as the basis of a 44-item…

  16. Complications of Lumbar Artificial Disc Replacement Compared to Fusion: Results From the Prospective, Randomized, Multicenter US Food and Drug Administration Investigational Device Exemption Study of the Charité Artificial Disc

    PubMed Central

    Majd, Mohammed E.; Isaza, Jorge E.; Blumenthal, Scott L.; McAfee, Paul C.; Guyer, Richard D.; Hochschuler, Stephen H.; Geisler, Fred H.; Garcia, Rolando; Regan, John J.

    2007-01-01

    Background Previous reports of lumbar total disc replacement (TDR) have described significant complications. The US Food and Drug Administration (FDA) investigational device exemption (IDE) study of the Charité artificial disc represents the first level I data comparison of TDR to fusion. Methods In the prospective, randomized, multicenter IDE study, patients were randomized in a 2:1 ratio, with 205 patients in the Charité group and 99 patients in the control group (anterior lumbar interbody fusion [ALIF] with BAK cages). Inclusion criteria included confirmed single-level degenerative disc disease at L4-5 or L5-S1 and failure of nonoperative treatment for at least 6 months. Complications were reported throughout the study. Results The rate of approach-related complications was 9.8% in the investigational group and 10.1% in the control group. The rate of major neurological complications was similar between the 2 groups (investigational = 4.4%, control = 4.0%). There was a higher rate of superficial wound infection in the investigational group but no deep wound infections in either group. Pseudarthrosis occurred in 9.1% of control group patients. The rate of subsidence in the investigational group was 3.4%. The reoperation rate was 5.4% in the investigational group and 9.1% in the control group. Conclusions The incidence of perioperative and postoperative complications for lumbar TDR was similar to that of ALIF. Vigilance is necessary with respect to patient indications, training, and correct surgical technique to maintain TDR complications at the levels experienced in the IDE study. PMID:25802575

  17. 17β-Estradiol (E-2) administration to male (NZB × SWR)F₁ mice results in increased Id(LN)F₁-reactive memory T-lymphocytes and accelerated glomerulonephritis.

    PubMed

    Feng, F; Silvin, C J; Fiore, N C; Stoll, M L; Price, K E; Shanley, P S; Silverstone, A E; Gavalchin, J

    2012-03-01

    While it has been shown that estradiol treatment accelerates the onset of lupus nephritis with autoantibody production and kidney damage in both male and female lupus-prone mice, the specific mechanism(s) involved are unknown. Our previous work has shown that alterations in Id(LN)F(1)-reactive T cells and Id(LN)F(1)+ antibodies correlated closely with the onset of autoimmune nephritis in female F(1) progeny of SWR and NZB (SNF(1)) mice, supporting a critical role for the Id(LN)F(1) idiotype in the development of disease. Since male SNF(1) mice normally do not develop nephritis, we tested whether administration of 17β-estradiol (E-2) to male SNF(1) mice would increase Id(LN)F(1) IgG levels and autoreactive T cells, and further, induce nephritis. We found that E-2-treated male SNF(1) mice developed nephritis with the same time course and mean survival as normal female SNF(1) mice. Moreover, it appeared that the mechanism involved increased serum Id(LN)F(1)(+)IgG and its deposition in kidney glomeruli, preceded by a striking twofold increase in T-lymphocytes expressing the memory phenotype (CD44(+)CD45RB(lo)) predominantly in the Id(LN)F(1)-reactive T-cell population. In addition, we noted that cells with this phenotype were increased in the nephritic kidneys of treated mice, suggesting a direct involvement of those cells in the renal pathology. E-2 treatment also induced increased numbers of pathogenic Id(LN)F(1)+ antibody-producing B cells and elevated presentation of pathogenic Id(LN)F(1)+ peptide. Taken together, these results suggest a mechanism of E-2-induced acceleration of autoimmune disease in lupus-prone mice may involve expansion of autoreactive idiotypic T and B-cell populations.

  18. Key drivers of airline loyalty

    PubMed Central

    Dolnicar, Sara; Grabler, Klaus; Grün, Bettina; Kulnig, Anna

    2011-01-01

    This study investigates drivers of airline loyalty. It contributes to the body of knowledge in the area by investigating loyalty for a number of a priori market segments identified by airline management and by using a method which accounts for the multi-step nature of the airline choice process. The study is based on responses from 687 passengers. Results indicate that, at aggregate level, frequent flyer membership, price, the status of being a national carrier and the reputation of the airline as perceived by friends are the variables which best discriminate between travellers loyal to the airline and those who are not. Differences in drivers of airline loyalty for a number of segments were identified. For example, loyalty programs play a key role for business travellers whereas airline loyalty of leisure travellers is difficult to trace back to single factors. For none of the calculated models satisfaction emerged as a key driver of airline loyalty. PMID:27064618

  19. The LCOGT Supernova Key Project

    NASA Astrophysics Data System (ADS)

    Howell, Dale Andrew; Arcavi, Iair; Hosseinzadeh, Griffin; McCully, Curtis; Valenti, Stefano; LCOGT Supernova Key Project

    2016-06-01

    We highlight results from the Las Cumbres Observatory Global Telescope (LCOGT) Supernova Key Project -- a 3 year program to obtain lightcurves and spectra of approximately 500 low-redshift SNe. LCOGT is a robotic network of elevent one and two meter telescopes spaced around the globe. We are involved in a variety of surveys, including the intermediate Palomar Transient Factory, LaSilla Quest, PESSTO, and KMTNet. Recent results include analysis of large samples of core-collaspe SNe, the largest sample of SNe Ibn, evidence of the progenitors of SNe Ia from companion shocking, and new findings about superluminious SNe.

  20. 75 FR 3444 - Availability of Seats for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... National Oceanic and Atmospheric Administration Availability of Seats for the Florida Keys National Marine... Florida Keys National Marine Sanctuary Advisory Council: Conservation and Environment (alternate), Fishing-- Commercial--Shell/Scale (alternate), Submerged Cultural Resources (alternate), and Tourism--Upper...

  1. College of DuPage Administrative Internship Program.

    ERIC Educational Resources Information Center

    College of DuPage, Glen Ellyn, IL.

    This paper describes the objectives, policies, and procedures of the College of DuPage's Administrative Internship Program, whereby faculty members can gain broad administrative experience in key administrative areas of the college. The program seeks not only to broaden the experience of the individual intern, but to promote empathy among faculty…

  2. The Keys to the White House

    ERIC Educational Resources Information Center

    Lichtman, Allan J.

    2012-01-01

    The Keys to the White House is a historically-based system for predicting the result of the popular vote in American presidential elections. The Keys system tracks the big picture of how well the party holding the White House has governed and does not shift with events of the campaign. This model gives specificity to the idea that it is…

  3. Simple Web-based interactive key development software (WEBiKEY) and an example key for Kuruna (Poaceae: Bambusoideae)1

    PubMed Central

    Attigala, Lakshmi; De Silva, Nuwan I.; Clark, Lynn G.

    2016-01-01

    Premise of the study: Programs that are user-friendly and freely available for developing Web-based interactive keys are scarce and most of the well-structured applications are relatively expensive. WEBiKEY was developed to enable researchers to easily develop their own Web-based interactive keys with fewer resources. Methods and Results: A Web-based multiaccess identification tool (WEBiKEY) was developed that uses freely available Microsoft ASP.NET technologies and an SQL Server database for Windows-based hosting environments. WEBiKEY was tested for its usability with a sample data set, the temperate woody bamboo genus Kuruna (Poaceae). Conclusions: WEBiKEY is freely available to the public and can be used to develop Web-based interactive keys for any group of species. The interactive key we developed for Kuruna using WEBiKEY enables users to visually inspect characteristics of Kuruna and identify an unknown specimen as one of seven possible species in the genus. PMID:27144109

  4. 76 FR 40336 - Availability of Seats for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... National Oceanic and Atmospheric Administration Availability of Seats for the Florida Keys National Marine... the Florida Keys National Marine Sanctuary Advisory Council: Boating Industry (alternate), Citizen at Large--Lower Keys (member), Citizen at Large--Lower Keys (alternate), Conservation and...

  5. 77 FR 5492 - Availability of Seat for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... National Oceanic and Atmospheric Administration Availability of Seat for the Florida Keys National Marine... Florida Keys National Marine Sanctuary Advisory Council: Tourism--Lower Keys (member), and Tourism--Lower Keys (alternate). Applicants are chosen based upon their particular expertise and experience...

  6. 76 FR 4868 - Availability of Seats for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... National Oceanic and Atmospheric Administration Availability of Seats for the Florida Keys National Marine... the Florida Keys National Marine Sanctuary Advisory Council: Boating Industry (alternate), Citizen at Large--Middle Keys (alternate), and Citizen at Large--Upper Keys (alternate). Applicants are...

  7. Nanofluids Research: Key Issues

    PubMed Central

    2010-01-01

    Nanofluids are a new class of fluids engineered by dispersing nanometer-size structures (particles, fibers, tubes, droplets) in base fluids. The very essence of nanofluids research and development is to enhance fluid macroscopic and megascale properties such as thermal conductivity through manipulating microscopic physics (structures, properties and activities). Therefore, the success of nanofluid technology depends very much on how well we can address issues like effective means of microscale manipulation, interplays among physics at different scales and optimization of microscale physics for the optimal megascale properties. In this work, we take heat-conduction nanofluids as examples to review methodologies available to effectively tackle these key but difficult problems and identify the future research needs as well. The reviewed techniques include nanofluids synthesis through liquid-phase chemical reactions in continuous-flow microfluidic microreactors, scaling-up by the volume averaging and constructal design with the constructal theory. The identified areas of future research contain microfluidic nanofluids, thermal waves and constructal nanofluids. PMID:20676214

  8. Transportation Security Administration

    MedlinePlus

    ... content Official website of the Department of Homeland Security Transportation Security Administration A - Z Index What Can I Bring? Search form Apples Main menu Administrator Travel Security Screening Special Procedures TSA Pre✓® Passenger Support Travel ...

  9. A Philosophy of Administration.

    ERIC Educational Resources Information Center

    Bruening, William H.

    Justification is given for paying relatively large salaries to college administrators, specifically the president or chancellor and the chief academic officer. Three administrative task areas are discussed as criteria: management, administration per se, and leadership. It is contended that only leadership can be used as a criterion for…

  10. Image encryption using fingerprint as key based on phase retrieval algorithm and public key cryptography

    NASA Astrophysics Data System (ADS)

    Zhao, Tieyu; Ran, Qiwen; Yuan, Lin; Chi, Yingying; Ma, Jing

    2015-09-01

    In this paper, a novel image encryption system with fingerprint used as a secret key is proposed based on the phase retrieval algorithm and RSA public key algorithm. In the system, the encryption keys include the fingerprint and the public key of RSA algorithm, while the decryption keys are the fingerprint and the private key of RSA algorithm. If the users share the fingerprint, then the system will meet the basic agreement of asymmetric cryptography. The system is also applicable for the information authentication. The fingerprint as secret key is used in both the encryption and decryption processes so that the receiver can identify the authenticity of the ciphertext by using the fingerprint in decryption process. Finally, the simulation results show the validity of the encryption scheme and the high robustness against attacks based on the phase retrieval technique.

  11. Key Concepts in Informatics: Algorithm

    ERIC Educational Resources Information Center

    Szlávi, Péter; Zsakó, László

    2014-01-01

    "The system of key concepts contains the most important key concepts related to the development tasks of knowledge areas and their vertical hierarchy as well as the links of basic key concepts of different knowledge areas." (Vass 2011) One of the most important of these concepts is the algorithm. In everyday life, when learning or…

  12. Individual Innovativeness Levels of Educational Administrators

    ERIC Educational Resources Information Center

    Coklar, Ahmet Naci

    2012-01-01

    In the present study carried out with 190 educational administrators, the individual innovativeness of educational administrators was examined. As a result of the study, it was found out that the educational administrators considered themselves as early adaptors. It was also revealed that professional seniority was not important in terms of…

  13. Musical key perception in relation to color.

    PubMed

    Firth, Ian C

    2014-12-01

    A link between musical keys and colors is common among musicians, although there has never been any agreement about which color matches which key. This study tested two alternative key-color associations: E is red and Eb is green, or vice versa. 21 participants (10 men, 11 women; M age = 20 yr., SD = 3.3) with absolute pitch listened to melodies beginning with an anacrusis and a perfect cadence which were played through in C major. Then the melodies began in another key, while four or two colored squares were displayed (in Experiments 1 and 2, respectively). Participants were asked to chose the color which best matched the quality of the new key. The results showed strong support for the E red / Eb green linkage. PMID:25539177

  14. The LCOGT Supernova Key Project

    NASA Astrophysics Data System (ADS)

    Howell, Dale Andrew; Arcavi, Iair; Hosseinzadeh, Griffin; McCully, Curtis; Valenti, Stefano; Lcogt Supernova Key Project

    2015-01-01

    I present first results from the Las Cumbres Observatory Global Telescope Network (LCOGT) Supernova Key Project. LCOGT is a network of 11 robotic one and two meter telescopes spaced around the globe with imaging and spectroscopic capabilities. The supernova key project is a 3 year program to obtain lightcurves and spectra of at least 450 supernovae. About half are expected to be core-collapse supernovae, and half thermonuclear. We will start light curves and spectroscopy within hours of discovery, and focus on those SNe caught soon after explosion. The goals are fivefold: (1) observe supernovae soon after explosion to search for signs of their progenitors, (2) obtain a large homogeneous sample of supernovae for next generation cosmological studies, (3) obtain a large sample of supernovae for statistical studies comparing groups that are split into different populations, (4) obtain some of the first large samples of the recently discovered classes of rare and exotic explosions, (5) obtain the optical light curves and spectroscopy in support of studies at other wavelengths and using other facilities including UV observations, IR imaging and spectroscopy, host galaxy studies, high resolution spectroscopy, and late-time spectroscopy with large telescopes.

  15. Securing information using optically generated biometric keys

    NASA Astrophysics Data System (ADS)

    Verma, Gaurav; Sinha, Aloka

    2016-11-01

    In this paper, we present a new technique to obtain biometric keys by using the fingerprint of a person for an optical image encryption system. The key generation scheme uses the fingerprint biometric information in terms of the amplitude mask (AM) and the phase mask (PM) of the reconstructed fingerprint image that is implemented using the digital holographic technique. Statistical tests have been conducted to check the randomness of the fingerprint PM key that enables its usage as an image encryption key. To explore the utility of the generated biometric keys, an optical image encryption system has been further demonstrated based on the phase retrieval algorithm and the double random phase encoding scheme in which keys for the encryption are used as the AM and the PM key. The advantage associated with the proposed scheme is that the biometric keys’ retrieval requires the simultaneous presence of the fingerprint hologram and the correct knowledge of the reconstruction parameters at the decryption stage, which not only verifies the authenticity of the person but also protects the valuable fingerprint biometric features of the keys. Numerical results are carried out to prove the feasibility and the effectiveness of the proposed encryption system.

  16. Key management approach of multicast

    NASA Astrophysics Data System (ADS)

    Jiang, Zhen; Wang, Xi-lian; Zhang, Hong-ke; Zhang, Li-yong

    2002-09-01

    A key management approach of multicast is provided in this paper. It is based on the approach of assignment key to every group member through key center. In view of some management schemes where members join, leave or are deleted, key service center must distribute new key through unicast another time. The bigger amount of members the greater expenses will be spent. In this paper with member varying their upper key service center still distribute the new keythrough multicast and an ID is assigned to every member to identify their transmission message so as to implement data origin authentication. The essential principle of this approach is distributing a key generator for each member. For example a random number generator depending on certain algorithm can be distributed. And every member needs store a seed table. In this project key can automatically be renewed as time goes by or immediately renewed. Replace unicast by multicast to renew key decrease the spending. It is not only suitable for the key centralized management scheme with fewer members but also for the key separated management scheme with large group members and member frequently changed.

  17. Limitations on quantum key repeaters.

    PubMed

    Bäuml, Stefan; Christandl, Matthias; Horodecki, Karol; Winter, Andreas

    2015-04-23

    A major application of quantum communication is the distribution of entangled particles for use in quantum key distribution. Owing to noise in the communication line, quantum key distribution is, in practice, limited to a distance of a few hundred kilometres, and can only be extended to longer distances by use of a quantum repeater, a device that performs entanglement distillation and quantum teleportation. The existence of noisy entangled states that are undistillable but nevertheless useful for quantum key distribution raises the question of the feasibility of a quantum key repeater, which would work beyond the limits of entanglement distillation, hence possibly tolerating higher noise levels than existing protocols. Here we exhibit fundamental limits on such a device in the form of bounds on the rate at which it may extract secure key. As a consequence, we give examples of states suitable for quantum key distribution but unsuitable for the most general quantum key repeater protocol.

  18. Limitations on quantum key repeaters.

    PubMed

    Bäuml, Stefan; Christandl, Matthias; Horodecki, Karol; Winter, Andreas

    2015-01-01

    A major application of quantum communication is the distribution of entangled particles for use in quantum key distribution. Owing to noise in the communication line, quantum key distribution is, in practice, limited to a distance of a few hundred kilometres, and can only be extended to longer distances by use of a quantum repeater, a device that performs entanglement distillation and quantum teleportation. The existence of noisy entangled states that are undistillable but nevertheless useful for quantum key distribution raises the question of the feasibility of a quantum key repeater, which would work beyond the limits of entanglement distillation, hence possibly tolerating higher noise levels than existing protocols. Here we exhibit fundamental limits on such a device in the form of bounds on the rate at which it may extract secure key. As a consequence, we give examples of states suitable for quantum key distribution but unsuitable for the most general quantum key repeater protocol. PMID:25903096

  19. Secure key storage and distribution

    DOEpatents

    Agrawal, Punit

    2015-06-02

    This disclosure describes a distributed, fault-tolerant security system that enables the secure storage and distribution of private keys. In one implementation, the security system includes a plurality of computing resources that independently store private keys provided by publishers and encrypted using a single security system public key. To protect against malicious activity, the security system private key necessary to decrypt the publication private keys is not stored at any of the computing resources. Rather portions, or shares of the security system private key are stored at each of the computing resources within the security system and multiple security systems must communicate and share partial decryptions in order to decrypt the stored private key.

  20. Administrators' perspectives of support for elementary science education

    NASA Astrophysics Data System (ADS)

    Hanegan, Nikki Notias

    This investigation examines administrators' perspectives of support for elementary science education through naturalistic inquiry methodologies. Determining how administrators, as instructional leaders, define and demonstrate support for innovative reform in one curriculum area, specifically in science, has a direct impact on teacher effectiveness to implement change and new curricula into classrooms. Six major areas of current literature were reviewed for this study. They were (1) the need for Elementary Science Education, (2) the current status of Elementary Science Education, (3) the need for science professional development, (4) key components for effective professional development implementation, (5) leadership for elementary science education, and (6) administrative support. These critical issues were selected to deepen the understanding and purpose of this study. As a result of emergent interviews, five major themes developed from this study. They are: (1) knowledge of science instruction and implementation, (2) demonstration of administrative leadership to promote science education, (3) providing necessary resources or materials, (4) providing professional development opportunities, and (5) fostering teacher leadership for science instruction. These themes are discussed with supporting evidence from respondent interviews and verified through teacher interviews, newsletters, web sites, school observations, or curriculum sources. Administrative support for elementary science education is defined as action taken to ascertain that students are receiving quality science instruction. Chapter Five includes a discussion on the effectiveness of managers versus leaders in science education reform. Administrators need more direct involvement and participation in professional development aimed at science education to develop leadership skills, science content knowledge, and tools necessary to develop leaders for future district and school planning to implement science

  1. Key sleep neurologic disorders

    PubMed Central

    St. Louis, Erik K.

    2014-01-01

    Summary Sleep disorders are frequent comorbidities in neurologic patients. This review focuses on clinical aspects and prognosis of 3 neurologic sleep disorders: narcolepsy, restless legs syndrome/Willis-Ekbom disease (RLS/WED), and REM sleep behavior disorder (RBD). Narcolepsy causes pervasive, enduring excessive daytime sleepiness, adversely affecting patients' daily functioning. RLS/WED is characterized by an uncomfortable urge to move the legs before sleep, often evolving toward augmentation and resulting in daylong bothersome symptoms. RBD causes potentially injurious dream enactment behaviors that often signify future evolution of overt synucleinopathy neurodegeneration in as many as 81% of patients. Timely recognition, referral for polysomnography, and longitudinal follow-up of narcolepsy, RLS/WED, and RBD patients are imperatives for neurologists in providing quality comprehensive patient care. PMID:24605270

  2. Advancing Administrative Supports for Research Development

    ERIC Educational Resources Information Center

    Briar-Lawson, Katharine; Korr, Wynne; White, Barbara; Vroom, Phyllis; Zabora, James; Middleton, Jane; Shank, Barbara; Schatz, Mona

    2008-01-01

    Research administrative supports must parallel and reinforce faculty initiatives in research grant procurement. This article features several types of developments that draw on presentations at the National Association of Deans and Directors of Schools of Social Work meetings. Key changes in social work programs are addressed, including the…

  3. 48 CFR 43.204 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... issued, but administrative changes and changes issued pursuant to a clause giving the Government a unilateral right to make a change (e.g., an option clause) initially require only one document. (b...) Dates of any pertinent Government actions or other key events during contract performance which may...

  4. Automated secured cost effective key refreshing technique to enhance WiMAX privacy key management

    NASA Astrophysics Data System (ADS)

    Sridevi, B.; Sivaranjani, S.; Rajaram, S.

    2013-01-01

    In all walks of life the way of communication is transformed by the rapid growth of wireless communication and its pervasive use. A wireless network which is fixed and richer in bandwidth is specified as IEEE 802.16, promoted and launched by an industrial forum is termed as Worldwide Interoperability for Microwave Access (WiMAX). This technology enables seamless delivery of wireless broadband service for fixed and/or mobile users. The obscurity is the long delay which occurs during the handoff management in every network. Mobile WiMAX employs an authenticated key management protocol as a part of handoff management in which the Base Station (BS) controls the distribution of keying material to the Mobile Station (MS). The protocol employed is Privacy Key Management Version 2- Extensible Authentication Protocol (PKMV2-EAP) which is responsible for the normal and periodical authorization of MSs, reauthorization as well as key refreshing. Authorization key (AK) and Traffic Encryption key (TEK) plays a vital role in key exchange. When the lifetime of key expires, MS has to request for a new key to BS which in turn leads to repetition of authorization, authentication as well as key exchange. To avoid service interruption during reauthorization , two active keys are transmitted at the same time by BS to MS. The consequences of existing work are hefty amount of bandwidth utilization, time consumption and large storage. It is also endured by Man in the Middle attack and Impersonation due to lack of security in key exchange. This paper designs an automatic mutual refreshing of keys to minimize bandwidth utilization, key storage and time consumption by proposing Previous key and Iteration based Key Refreshing Function (PKIBKRF). By integrating PKIBKRF in key generation, the simulation results indicate that 21.8% of the bandwidth and storage of keys are reduced and PKMV2 mutual authentication time is reduced by 66.67%. The proposed work is simulated with Qualnet model and

  5. Input from Key Stakeholders in the National Security Technology Incubator

    SciTech Connect

    2008-01-31

    This report documents the input from key stakeholders of the National Security Technology Incubator (NSTI) in developing a new technology incubator and related programs for southern New Mexico. The technology incubator is being developed as part of the National Security Preparedness Project (NSPP), funded by a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. This report includes identification of key stakeholders as well as a description and analysis of their input for the development of an incubator.

  6. Key Objectives Bank: Year 7. Key Stage 3: National Strategy.

    ERIC Educational Resources Information Center

    Department for Education and Skills, London (England).

    In each sub-section of the "Framework for Teaching English: Years 7, 8 and 9," certain key objectives are identified in boldface print. These objectives are key because they signify skills or understanding which are crucial to pupil's language development. They are challenging for the age group and are important markers of progress. This key…

  7. Veterans Administration Databases

    Cancer.gov

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  8. Interventions delivered in clinical settings are effective in reducing risk of HIV transmission among people living with HIV: results from the Health Resources and Services Administration (HRSA)'s Special Projects of National Significance initiative.

    PubMed

    Myers, Janet J; Shade, Starley B; Rose, Carol Dawson; Koester, Kimberly; Maiorana, Andre; Malitz, Faye E; Bie, Jennifer; Kang-Dufour, Mi-Suk; Morin, Stephen F

    2010-06-01

    To support expanded prevention services for people living with HIV, the US Health Resources and Services Administration (HRSA) sponsored a 5-year initiative to test whether interventions delivered in clinical settings were effective in reducing HIV transmission risk among HIV-infected patients. Across 13 demonstration sites, patients were randomized to one of four conditions. All interventions were associated with reduced unprotected vaginal and/or anal intercourse with persons of HIV-uninfected or unknown status among the 3,556 participating patients. Compared to the standard of care, patients assigned to receive interventions from medical care providers reported a significant decrease in risk after 12 months of participation. Patients receiving prevention services from health educators, social workers or paraprofessional HIV-infected peers reported significant reduction in risk at 6 months, but not at 12 months. While clinics have a choice of effective models for implementing prevention programs for their HIV-infected patients, medical provider-delivered methods are comparatively robust.

  9. 78 FR 5779 - Availability of Seats for the Florida Keys National Marine Sanctuary Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... National Oceanic and Atmospheric Administration Availability of Seats for the Florida Keys National Marine... Florida Keys National Marine Sanctuary Advisory Council: Boating Industry (alternate), and Fishing...: Application kits may be obtained from Beth Dieveney, Florida Keys National Marine Sanctuary, 33 East Quay...

  10. 75 FR 7045 - Key Gas Components, Inc., Marion, NC; Notice of Negative Determination Regarding Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-16

    ... Employment and Training Administration Key Gas Components, Inc., Marion, NC; Notice of Negative Determination... TAA petition filed on behalf of workers at Key Gas Components, Inc., Marion, North Carolina was based... petitioner alleged that Key Gas Components imports these articles. The initial investigation did, in...

  11. The Administrative Power Grab

    ERIC Educational Resources Information Center

    Sorenson, Richard D.

    2007-01-01

    Administrative power for some school teachers can be an aphrodisiac that can be applied negatively, especially when a leader has devastating instinct for the weaknesses of others. A leader's intellect and heart closes shop and ceases to function when drunk on power. In this article, the author describes how the use of administrative power can be…

  12. Innovation in Administrator Preparation.

    ERIC Educational Resources Information Center

    Coleman, Don

    An innovative administrator preparation program based on guidelines established by national boards and commissions is described in this paper. The California State University, Fresno, administrator education curriculum was reorganized by faculty and an advisory committee of 11 superintendents to meet the needs of local school districts. The…

  13. Migrant Education Administrative Guide.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Compensatory Education.

    Relating specifically to the North Carolina migrant education program's administrative responsibilities, this guide is designed to aid administrators in program management, monitoring project activities, project evaluation, self-assessment, determining needs for training and staff development, site-visit preparation, policy development, and…

  14. Administration of Computer Resources.

    ERIC Educational Resources Information Center

    Franklin, Gene F.

    Computing at Stanford University has, until recently, been performed at one of five facilities. The Stanford hospital operates an IBM 370/135 mainly for administrative use. The university business office has an IBM 370/145 for its administrative needs and support of the medical clinic. Under the supervision of the Stanford Computation Center are…

  15. Issues in Educational Administration.

    ERIC Educational Resources Information Center

    Ediger, Marlow

    School administrators need to study and analyze the pros and cons of issues before making decisions. Ultimately, decisions need to be made by administrators as to which philosophies of education to implement in resolving conflicting points of view. More research studies would lead to an increased number of syntheses of the pros and cons of certain…

  16. Justifying Educational Administration.

    ERIC Educational Resources Information Center

    Evers, Colin; Lakomski, Gabriele

    1993-01-01

    The traditional conceptions of science dominating educational administration are mistaken. Unacceptable epistemologies, like those implicit in logical positivism, justify knowledge solely in terms of empirical adequacy. An improved science of educational administration embraces a coherent global theory accounting for all the phenomena of human…

  17. Test Administration Models

    ERIC Educational Resources Information Center

    Becker, Kirk A.; Bergstrom, Betty A.

    2013-01-01

    The need for increased exam security, improved test formats, more flexible scheduling, better measurement, and more efficient administrative processes has caused testing agencies to consider converting the administration of their exams from paper-and-pencil to computer-based testing (CBT). Many decisions must be made in order to provide an optimal…

  18. Champions of Children. Administrators . . .

    ERIC Educational Resources Information Center

    Chaffee, John; Olds, H. Robert

    Today, in an era of taxpayer revolts, lack of clarity in values, and changing family structure, children need advocates in the political arena as well as in the schools. This pamphlet suggests that administrators are in an excellent position to defend the rights of children on all fronts. It focuses on what administrators have done and specific…

  19. The School Personnel Administrator.

    ERIC Educational Resources Information Center

    Knox, Rodney F.

    This paper provides an overview of the development of the school-personnel administrator role. It first describes the influence of the science-management and human-relations movements and the behavioral sciences on personnel administration and human resource management. It next discusses the role of the personnel-performance-appraisal system and…

  20. Tenure for Administrators?

    ERIC Educational Resources Information Center

    Holyer, Robert

    2004-01-01

    The practice of granting tenure to academic administrators, especially presidents and academic deans, seems fairly prevalent. However, it is important to consider the possible advantages and disadvantages carefully before making such an offer. Boards interested in attracting talented administrators empowered to do what is in the best interest of…

  1. 47 CFR 54.715 - Administrative expenses of the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Administrative expenses of the Administrator. 54.715 Section 54.715 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.715 Administrative expenses of the Administrator. (a) The annual administrative expenses...

  2. Administrative Utility Analysis: Study Summary.

    ERIC Educational Resources Information Center

    Peat, Marwick, Mitchell and Co., San Juan, Puerto Rico.

    This document summarizes the recommendations made as a result of a study on administrative utility analysis and vocational education programs for Puerto Rico. The major recommendation was that the Area of Vocational and Technical Education (AVTE) in the Puerto Rico Department of Education be restructured at the central organizational level, for…

  3. Research Administrators as Servant Leaders

    ERIC Educational Resources Information Center

    Waite, Joann

    2011-01-01

    Within the sponsored research support offices in departments at research institutions, non-profits, and undergraduate institutions, research administrators are often perceived as servant leaders by their own membership organizations and those who work with them. This perception is influenced by survey results focusing on character. Parolini (2004)…

  4. Evaluating Administrative/Supervisory Performance.

    ERIC Educational Resources Information Center

    Educational Research Service, Arlington, VA.

    This is a report on the third survey conducted on procedures for evaluating the performance of administrators and supervisors in local school systems. A questionnaire was sent to school systems enrolling 25,000 or more pupils, and results indicated that 84 of the 154 responding systems have formal evaluation procedures. Tables and discussions of…

  5. 14 CFR 1216.302 - Definition of key terms.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... content includes the national fleet of Space Shuttle orbiters, including main engines, launch site and... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Definition of key terms. 1216.302 Section 1216.302 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION ENVIRONMENTAL...

  6. Stress and Educational Administration: Variations in Stress Factors across Administrative Levels.

    ERIC Educational Resources Information Center

    Frick, Cynthia R.; Fraas, John W.

    Factors and perceptions of stress in educational administration are examined in this report. A survey of 86 administrators in Richland County, Ohio, in which the Administrative Stress Index was used to explore causes of stress and to rate the severity of each stressor, yielded a 97 percent response rate. Results were statistically analyzed for…

  7. How to start and sustain a successful pediatric cardiac intensive care program: A combined clinical and administrative strategy.

    PubMed

    Chang, Anthony C.

    2002-04-01

    OBJECTIVE: To delineate key clinical and administrative factors in starting a pediatric cardiac intensive care program and to introduce a scorecard concept to measure excellence in such a new program. Methods: Review of current clinical research data in pediatric cardiac intensive care and administrative business concepts for their application to the pediatric cardiac intensive care program. RESULTS: Although clinical concepts in cardiac intensive care are useful as basic philosophical strategies at the bedside, administrative principles are essential in operational strategies vital to the success of such a program. Using both clinical and business administrative concepts, a balanced strategy can be formulated. CONCLUSIONS: Starting a pediatric cardiac intensive care program is a difficult endeavor. A combined clinical and administrative approach is needed in starting and sustaining excellence in a pediatric cardiac intensive care program. Monitoring excellence in such a program warrants application of a scorecard system. PMID:12780977

  8. Special Education Administrators' Perspectives on Response to Intervention

    ERIC Educational Resources Information Center

    Wiener, Roberta M.; Soodak, Leslie C.

    2008-01-01

    A national survey was conducted to provide information on the preparedness and conditions necessary for schools to implement the response to intervention model (RtI). Because of the key role of administrators in determining the success of policy implementation, the present study was designed to assess special education administrators'…

  9. Gender and Leadership in South African Educational Administration.

    ERIC Educational Resources Information Center

    Chisholm, Linda

    2001-01-01

    Examines the phenomenon of South Africa's simultaneous transformation of its educational administration and the consolidation of earlier patriarchal forms of control. Using data from interviews with key department of education administrators, the article suggests that these developments can be explained by particular constructs and practices of…

  10. Graduate Education for Hospital Administration in the United States: Trends.

    ERIC Educational Resources Information Center

    Chester, Theodore E.

    In 1968, 75% of the 5,466 graduates of hospital administration were in management positions in hospitals and related institutions, and about 1,000 to 1,500 held key government jobs. The US needs approximately 40,000 trained hospital administrators, but the total graduate output is about one-eighth of that amount. Of the 23 existing programs, 8 are…

  11. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis

    PubMed Central

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    Background This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Methodology/Principal Findings Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006–2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006–2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including “natural products and polymers” with nine key technical points, “fermentation industry” with twelve ones, “electrical medical equipment” with four ones, and “diagnosis, surgery” with four ones. Conclusions/Significance The results of this study could provide guidance on the development

  12. Experimental quantum key distribution with finite-key security analysis for noisy channels.

    PubMed

    Bacco, Davide; Canale, Matteo; Laurenti, Nicola; Vallone, Giuseppe; Villoresi, Paolo

    2013-01-01

    In quantum key distribution implementations, each session is typically chosen long enough so that the secret key rate approaches its asymptotic limit. However, this choice may be constrained by the physical scenario, as in the perspective use with satellites, where the passage of one terminal over the other is restricted to a few minutes. Here we demonstrate experimentally the extraction of secure keys leveraging an optimal design of the prepare-and-measure scheme, according to recent finite-key theoretical tight bounds. The experiment is performed in different channel conditions, and assuming two distinct attack models: individual attacks or general quantum attacks. The request on the number of exchanged qubits is then obtained as a function of the key size and of the ambient quantum bit error rate. The results indicate that viable conditions for effective symmetric, and even one-time-pad, cryptography are achievable.

  13. Experimental quantum key distribution with finite-key security analysis for noisy channels.

    PubMed

    Bacco, Davide; Canale, Matteo; Laurenti, Nicola; Vallone, Giuseppe; Villoresi, Paolo

    2013-01-01

    In quantum key distribution implementations, each session is typically chosen long enough so that the secret key rate approaches its asymptotic limit. However, this choice may be constrained by the physical scenario, as in the perspective use with satellites, where the passage of one terminal over the other is restricted to a few minutes. Here we demonstrate experimentally the extraction of secure keys leveraging an optimal design of the prepare-and-measure scheme, according to recent finite-key theoretical tight bounds. The experiment is performed in different channel conditions, and assuming two distinct attack models: individual attacks or general quantum attacks. The request on the number of exchanged qubits is then obtained as a function of the key size and of the ambient quantum bit error rate. The results indicate that viable conditions for effective symmetric, and even one-time-pad, cryptography are achievable. PMID:24008848

  14. Finite-key security analysis for multilevel quantum key distribution

    NASA Astrophysics Data System (ADS)

    Brádler, Kamil; Mirhosseini, Mohammad; Fickler, Robert; Broadbent, Anne; Boyd, Robert

    2016-07-01

    We present a detailed security analysis of a d-dimensional quantum key distribution protocol based on two and three mutually unbiased bases (MUBs) both in an asymptotic and finite-key-length scenario. The finite secret key rates (in bits per detected photon) are calculated as a function of the length of the sifted key by (i) generalizing the uncertainly relation-based insight from BB84 to any d-level 2-MUB QKD protocol and (ii) by adopting recent advances in the second-order asymptotics for finite block length quantum coding (for both d-level 2- and 3-MUB QKD protocols). Since the finite and asymptotic secret key rates increase with d and the number of MUBs (together with the tolerable threshold) such QKD schemes could in principle offer an important advantage over BB84. We discuss the possibility of an experimental realization of the 3-MUB QKD protocol with the orbital angular momentum degrees of freedom of photons.

  15. Thoughts for New Administrators

    ERIC Educational Resources Information Center

    LaCrosse, E. Robert

    1977-01-01

    Discusses issues in program administration, with specific reference to preschool programs. Some of the issues discussed include coping with conflict, leadership, the sharing of power, and honesty. A short annotated bibliography is included. (BD)

  16. Serving the Space Administration

    ERIC Educational Resources Information Center

    Campbell, Jack E.; Thompson, Arthur W.

    1974-01-01

    The purpose of the current program was to establish an upward mobility program that afforded employees an opportunity to improve their credibility in job opportunity selection under the directives of the National Aeronautics and Space Administration. (Author/RK)

  17. Goldstone (GDSCC) administrative computing

    NASA Technical Reports Server (NTRS)

    Martin, H.

    1981-01-01

    The GDSCC Data Processing Unit provides various administrative computing services for Goldstone. Those activities, including finance, manpower and station utilization, deep-space station scheduling and engineering change order (ECO) control are discussed.

  18. Administrators Speak Out

    ERIC Educational Resources Information Center

    Miner, Fred V.

    1976-01-01

    A summary is presented of the issues and concerns discussed and the recommendations made by the American Vocational Association's (AVA) Administration Policy Committee during its meeting at the 1975 AVA Convention. (AJ)

  19. A comparison of keyed and non-keyed vaporizer filling modes and volatile agent wastage.

    PubMed

    Uncles, D R

    1993-09-01

    Two hundred and forty bottles of enflurane were collected after their contents had been emptied into vaporizers equipped with keyed or non-keyed filling ports. The volume of agent remaining, the residual volume, was measured. There was a greater (p < 0.001) residual volume in 'empty' bottles which had been used to fill keyed compared with non-keyed enflurane vaporizers. Five hundred and fifty two bottles of isoflurane were also collected after they had been used to fill keyed vaporizers. There was no significant difference between the residual volume remaining in bottles of isoflurane and enflurane used to fill keyed fillers; however, the difference was statistically significant if the residual volume was expressed as a proportion to the volume of agent contained in the full bottle. The results show that volatile anaesthetic agent wastage is increased by the use of keyed fillers. Isoflurane wastage caused by utilisation of keyed fillers could be reduced by a factor of 2.5 by supplying isoflurane in 250 ml rather than 100 ml bottles.

  20. Business Department Chairperson: An Administrator or a Teacher?

    ERIC Educational Resources Information Center

    O'Neil, Bryan L.

    The responsibilities of the business department chairperson at Castleton State College were assessed. A literature review included the area of organizational structures of academic institutions, and key faculty members and administrators at the college were interviewed to identify the key issues and problems of organizational structures and job…

  1. Effects of intermittent versus continuous parathyroid hormone administration on condylar chondrocyte proliferation and differentiation

    SciTech Connect

    Liu, Qi; Wan, Qilong; Yang, Rongtao; Zhou, Haihua; Li, Zubing

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Different PTH administration exerts different effects on condylar chondrocyte. Black-Right-Pointing-Pointer Intermittent PTH administration suppresses condylar chondrocyte proliferation. Black-Right-Pointing-Pointer Continuous PTH administration maintains condylar chondrocyte proliferating. Black-Right-Pointing-Pointer Intermittent PTH administration enhances condylar chondrocyte differentiation. -- Abstract: Endochondral ossification is a complex process involving chondrogenesis and osteogenesis regulated by many hormones and growth factors. Parathyroid hormone (PTH), one of the key hormones regulating bone metabolism, promotes osteoblast differentiation and osteogenesis by intermittent administration, whereas continuous PTH administration inhibits bone formation. However, the effects of PTH on chondrocyte proliferation and differentiation are still unclear. In this study, intermittent PTH administration presented enhanced effects on condylar chondrocyte differentiation and bone formation, as demonstrated by increased mineral nodule formation and alkaline phosphatase (ALP) activity, up-regulated runt-related transcription factor 2 (RUNX2), ALP, collagen type X (COL10a1), collagen type I (COL1a1), osteocalcin (OCN), bone sialoprotein (BSP), bone morphogenetic protein 2 (BMP2) and osterix (OSX) mRNA and/or protein expression. On the contrary, continuous PTH administration promoted condylar chondrocyte proliferation and suppressed its differentiation, as demonstrated by up-regulated collagen type II (COL2a1) mRNA expression, reduced mineral nodule formation and down-regulated expression of the mRNAs and/or proteins mentioned above. Our data suggest that PTH can regulate condylar chondrocyte proliferation and differentiation, depending on the type of PTH administration. These results provide new insight into the effects of PTH on condylar chondrocytes and new evidence for using local PTH administration to cure mandibular

  2. Key issues in transplant tourism.

    PubMed

    Akoh, Jacob A

    2012-02-24

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations. PMID:24175191

  3. Key issues in transplant tourism.

    PubMed

    Akoh, Jacob A

    2012-02-24

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations.

  4. Key issues in transplant tourism

    PubMed Central

    Akoh, Jacob A

    2012-01-01

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations. PMID:24175191

  5. 75 FR 48309 - First Antidumping Duty Administrative Review of Sodium Hexametaphosphate from the People's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... the Antidumping Duty Administrative Review, 75 FR 19613 (April 15, 2010) (``Preliminary Results... International Trade Administration First Antidumping Duty Administrative Review of Sodium Hexametaphosphate from... first administrative review of sodium hexametaphosphate (``sodium hex'') from the People's Republic...

  6. 76 FR 73599 - Second Administrative Review of Sodium Hexametaphosphate From the People's Republic of China...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    .... \\1\\ See Initiation of Antidumping and Countervailing Duty Administrative Reviews, 76 FR 23545 (April... International Trade Administration Second Administrative Review of Sodium Hexametaphosphate From the People's... time limit for the preliminary results of the administrative review of sodium...

  7. An absolute measure for a key currency

    NASA Astrophysics Data System (ADS)

    Oya, Shunsuke; Aihara, Kazuyuki; Hirata, Yoshito

    It is generally considered that the US dollar and the euro are the key currencies in the world and in Europe, respectively. However, there is no absolute general measure for a key currency. Here, we investigate the 24-hour periodicity of foreign exchange markets using a recurrence plot, and define an absolute measure for a key currency based on the strength of the periodicity. Moreover, we analyze the time evolution of this measure. The results show that the credibility of the US dollar has not decreased significantly since the Lehman shock, when the Lehman Brothers bankrupted and influenced the economic markets, and has increased even relatively better than that of the euro and that of the Japanese yen.

  8. Bayesian hypothesis testing for key comparisons

    NASA Astrophysics Data System (ADS)

    Wübbeler, Gerd; Bodnar, Olha; Elster, Clemens

    2016-08-01

    Unilateral degrees of equivalence are the key result in the analysis of key comparison data and they are used to approve, or disapprove, calibration and measurement capabilities of the participating laboratories. To this end, it is checked whether a degree of equivalence differs significantly from zero. Proceeding in such a way can be viewed as carrying out a classical hypothesis test. We develop a Bayesian counterpart to this approach which has the advantage that it can include prior assessment of the corresponding Consultative Committee about the calibration and measurement capabilities of the participating laboratories. Simple expressions are derived and their implementation is provided in terms of MATLAB® and R programs. The novel procedure is illustrated by its application to two recent key comparisons CCL-K1 and CCM.FF-K4.1.2011.

  9. [Ante-partum administration of preventive treatment of Rh-D immunization in rhesus-negative women. Parallel evaluation of transplacental passage of fetal blood cells. Results of a multicenter study carried out in the Paris region].

    PubMed

    Huchet, J; Dallemagne, S; Huchet, C; Brossard, Y; Larsen, M; Parnet-Mathieu, F

    1987-01-01

    1,969 non immunized rhesus negative primiparous women were followed up in 23 maternity units in the geographical region of Paris. 1,882 could be retained to study antepartum protection and 1,884 to study transplacental passage of fetal blood cells. Two groups were defined according to whether they were born in even or uneven years, so that: 955 were the "control" group who delivered 590 rhesus D positive infants, and 927 were the "treated" group who delivered 599 rhesus D positive infants. The "control" group were used as controls at the 28th and 34th weeks of pregnancy, while the "treated" group received two injections of anti-D immunoglobulin given on the same dates after taking the necessary tests. Immunological testing at the time of the delivery and after the delivery showed that 7 women had become Rh D immunized in the "control" group whereas only one in the "treated" group. This difference, which is statistically significant, confirms the results of other authors about the efficiency of antepartum rhesus disease prevention. The incidence of immunisation during or immediately after the first pregnancy in women who had no previous story of blood transfusions or of terminations of pregnancy is 1.11%, which is a figure relatively low as compared with studies of series carried out in North America, but close to those carried out in other European centres. When primipara of all categories are lumped together the frequency rises to 1.5%. A study of the passage of fetal red blood cells into the maternal circulation shows that at the 29th week of pregnancy out of 1,884 cases there were 5.5% positive kleihauer tests, without a large volume of blood being detected and at the 34th week of pregnancy when 957 tests were carried out, 7% were positive with one of them being of a massive transfusion of blood from the fetus to the mother, which was life-threatening for the fetus. It may be that the incidence had been under-estimated and that the positive results in the two

  10. Key China Energy Statistics 2012

    SciTech Connect

    Levine, Mark; Fridley, David; Lu, Hongyou; Fino-Chen, Cecilia

    2012-05-01

    The China Energy Group at Lawrence Berkeley National Laboratory (LBNL) was established in 1988. Over the years the Group has gained recognition as an authoritative source of China energy statistics through the publication of its China Energy Databook (CED). The Group has published seven editions to date of the CED (http://china.lbl.gov/research/chinaenergy-databook). This handbook summarizes key statistics from the CED and is expressly modeled on the International Energy Agency’s “Key World Energy Statistics” series of publications. The handbook contains timely, clearly-presented data on the supply, transformation, and consumption of all major energy sources.

  11. Key China Energy Statistics 2011

    SciTech Connect

    Levine, Mark; Fridley, David; Lu, Hongyou; Fino-Chen, Cecilia

    2012-01-15

    The China Energy Group at Lawrence Berkeley National Laboratory (LBNL) was established in 1988. Over the years the Group has gained recognition as an authoritative source of China energy statistics through the publication of its China Energy Databook (CED). In 2008 the Group published the Seventh Edition of the CED (http://china.lbl.gov/research/chinaenergy-databook). This handbook summarizes key statistics from the CED and is expressly modeled on the International Energy Agency’s “Key World Energy Statistics” series of publications. The handbook contains timely, clearly-presented data on the supply, transformation, and consumption of all major energy sources.

  12. Florida Everglades and Keys, USA

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Though much of southern Florida is covered by clouds, the Florida Everglades and Keys (25.0N, 82.0W) remain relatively clear in this nearly vertical view. The view covers the Gulf of Mexico port city of Ft. Myers, and Lake Okeechobee, at the top of the scene, in the north, The Everglades, in the center and the entire Florida Key Chain at the bottom. Even with the many popcorn clouds, ground detail and the city of Miami is easily discerned.

  13. 75 FR 68416 - Administrative Wage Garnishment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... 31 U.S.C. 3720D(h)) with respect to administrative wage garnishment. On May 6, 1998 (63 FR 25136... circumstances--such as disability, divorce, or catastrophic illness--which result in financial hardship. III... administration, Salaries, Wages. ] Authority and Issuance 0 For the reasons set forth above, the Federal...

  14. The Underlying Processes of Athletic Administration.

    ERIC Educational Resources Information Center

    Leith, Larry M.

    1983-01-01

    Athletic administration is a diverse subject area requiring competence in many skills. The process of administration refers to the planning, organizing, leading, and controlling that takes place to accomplish objectives. This paper examines these four elements and suggests how using these principles will result in more efficient athletic…

  15. 50 CFR 253.24 - Administrative requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Administrative requirements. 253.24 Section 253.24 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Fisheries § 253.24 Administrative requirements. Federal assistance awards made as a result of this Act...

  16. 50 CFR 253.54 - Administrative requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Administrative requirements. 253.54 Section 253.54 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Fisheries § 253.54 Administrative requirements. Federal assistance awards made as a result of this Act...

  17. Voices from the Field: Central Office Administrators

    ERIC Educational Resources Information Center

    Dickson, Ken

    2015-01-01

    School systems' central office administrators sometimes take paths that seem easiest, even when it is clear the paths will not lead to sustained positive results that are needed--particularly in terms of twice-exceptional (2e) students. To appropriately address the needs of 2e learners, we must ensure that central office administrative services…

  18. Key Issues in Hadronic Physics

    SciTech Connect

    Simon Capstick; et. Al.

    2000-12-01

    A group of fifty physicists met in Duck, NC, Nov. 6-9 to discuss the current status and future goals of hadronic physics. The main purpose of the meeting was to define the field by identifying its key issues, challenges, and opportunities. The conclusions, incorporating considerable input from the community at large, are presented in this white paper.

  19. Ten Keys to the Portal

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2011-01-01

    Successful web portals help users stay informed, in touch, and up to speed. They are also a telling window into the efficiency of one's institution. To develop a cutting-edge portal takes planning, communication, and research. In this article, the author presents and discusses 10 keys to portal success: (1) make critical info visible; (2) make the…

  20. Key Issues in Infant Mortality.

    ERIC Educational Resources Information Center

    Falkner, Frank, Ed.

    This pamphlet summarizes the proceedings of a conference on infant mortality sponsored by the National Institute of Child Health and Human Development. Participants were 25 people engaged in various disciplines (physicians, nurses, social workers, sociologists, statisticians and others) who discussed key issues on the basis of their own knowledge…

  1. School Leadership: Some Key Ideas.

    ERIC Educational Resources Information Center

    Fidler, Brian

    1997-01-01

    Highlights some key ideas and several perspectives on leadership, including: situational leadership; a leadership framework suggested by T.E. Deal and L.G. Bolman; leadership of the chief executive/leading professional; moral leadership; and curricular leadership. Identifies leadership by its contribution to outcomes and its influence on…

  2. Metrics for Key Punch Operators.

    ERIC Educational Resources Information Center

    Cooper, Gloria S., Ed.; Magisos, Joel H., Ed.

    Designed to meet the job-related metric measurement needs of key punch operator students, this instructional package is one of three for the business and office occupations cluster, part of a set of 55 packages for metric instruction in different occupations. The package is intended for students who already know the occupational terminology,…

  3. Key for Trees of Iowa.

    ERIC Educational Resources Information Center

    Coder, Kim D.; Wray, Paul H.

    This key is designed to help identify the most common trees found in Iowa. It is based on vegetative characteristics such as leaves, fruits, and bark and is illustrated with black and white line drawings. Since vegetative characteristics vary due to climate, age, soil fertility, and other conditions, the numerical sizes listed, such as length and…

  4. Key Skills and Competencies. Symposium.

    ERIC Educational Resources Information Center

    2002

    This document contains three papers on key skills and competencies and human resource development (HRD). "Career Related Competencies" (Marinka A.C.T. Kuijpers) reports findings from surveys completed by Dutch employees who identified these issues: self-reflection is more important than career control; age and gender influence attitude toward…

  5. MCS Systems Administration Toolkit

    2001-09-30

    This package contains a number of systems administration utilities to assist a team of system administrators in managing a computer environment by automating routine tasks and centralizing information. Included are utilities to help install software on a network of computers and programs to make an image of a disk drive, to manage and distribute configuration files for a number of systems, and to run self-testss on systems, as well as an example of using amore » database to manage host information and various utilities.« less

  6. Computer hardware fault administration

    DOEpatents

    Archer, Charles J.; Megerian, Mark G.; Ratterman, Joseph D.; Smith, Brian E.

    2010-09-14

    Computer hardware fault administration carried out in a parallel computer, where the parallel computer includes a plurality of compute nodes. The compute nodes are coupled for data communications by at least two independent data communications networks, where each data communications network includes data communications links connected to the compute nodes. Typical embodiments carry out hardware fault administration by identifying a location of a defective link in the first data communications network of the parallel computer and routing communications data around the defective link through the second data communications network of the parallel computer.

  7. River basin administration

    NASA Astrophysics Data System (ADS)

    Management of international rivers and their basins is the focus of the Centre for Comparative Studies on (International) River Basin Administration, recently established at Delft University of Technology in the Netherlands. Water pollution, sludge, and conflicting interests in the use of water in upstream and downstream parts of a river basin will be addressed by studying groundwater and consumption of water in the whole catchment area of a river.Important aspects of river management are administrative and policy aspects. The Centre will focus on policy, law, planning, and organization, including transboundary cooperation, posing standards, integrated environmental planning on regional scale and environmental impact assessments.

  8. Key Reconciliation for High Performance Quantum Key Distribution

    PubMed Central

    Martinez-Mateo, Jesus; Elkouss, David; Martin, Vicente

    2013-01-01

    Quantum Key Distribution is carving its place among the tools used to secure communications. While a difficult technology, it enjoys benefits that set it apart from the rest, the most prominent is its provable security based on the laws of physics. QKD requires not only the mastering of signals at the quantum level, but also a classical processing to extract a secret-key from them. This postprocessing has been customarily studied in terms of the efficiency, a figure of merit that offers a biased view of the performance of real devices. Here we argue that it is the throughput the significant magnitude in practical QKD, specially in the case of high speed devices, where the differences are more marked, and give some examples contrasting the usual postprocessing schemes with new ones from modern coding theory. A good understanding of its implications is very important for the design of modern QKD devices. PMID:23546440

  9. Key Reconciliation for High Performance Quantum Key Distribution

    NASA Astrophysics Data System (ADS)

    Martinez-Mateo, Jesus; Elkouss, David; Martin, Vicente

    2013-04-01

    Quantum Key Distribution is carving its place among the tools used to secure communications. While a difficult technology, it enjoys benefits that set it apart from the rest, the most prominent is its provable security based on the laws of physics. QKD requires not only the mastering of signals at the quantum level, but also a classical processing to extract a secret-key from them. This postprocessing has been customarily studied in terms of the efficiency, a figure of merit that offers a biased view of the performance of real devices. Here we argue that it is the throughput the significant magnitude in practical QKD, specially in the case of high speed devices, where the differences are more marked, and give some examples contrasting the usual postprocessing schemes with new ones from modern coding theory. A good understanding of its implications is very important for the design of modern QKD devices.

  10. Public key infrastructure for DOE security research

    SciTech Connect

    Aiken, R.; Foster, I.; Johnston, W.E.

    1997-06-01

    This document summarizes the Department of Energy`s Second Joint Energy Research/Defence Programs Security Research Workshop. The workshop, built on the results of the first Joint Workshop which reviewed security requirements represented in a range of mission-critical ER and DP applications, discussed commonalties and differences in ER/DP requirements and approaches, and identified an integrated common set of security research priorities. One significant conclusion of the first workshop was that progress in a broad spectrum of DOE-relevant security problems and applications could best be addressed through public-key cryptography based systems, and therefore depended upon the existence of a robust, broadly deployed public-key infrastructure. Hence, public-key infrastructure ({open_quotes}PKI{close_quotes}) was adopted as a primary focus for the second workshop. The Second Joint Workshop covered a range of DOE security research and deployment efforts, as well as summaries of the state of the art in various areas relating to public-key technologies. Key findings were that a broad range of DOE applications can benefit from security architectures and technologies built on a robust, flexible, widely deployed public-key infrastructure; that there exists a collection of specific requirements for missing or undeveloped PKI functionality, together with a preliminary assessment of how these requirements can be met; that, while commercial developments can be expected to provide many relevant security technologies, there are important capabilities that commercial developments will not address, due to the unique scale, performance, diversity, distributed nature, and sensitivity of DOE applications; that DOE should encourage and support research activities intended to increase understanding of security technology requirements, and to develop critical components not forthcoming from other sources in a timely manner.

  11. The Liability Chase Game: Reducing Financial Liability Resulting from JTPA Program Implementation. Employment and Training Issues.

    ERIC Educational Resources Information Center

    Dillon, Barbara; Smithson, Craig

    Directed to Service Delivery Area (SDA) administrators but also useful to local elected officials and Private Industry Council members in determining key areas for their review, this document provides suggestions to SDAs on preventive activities that can assist in reducing disallowed costs resulting from the improper operation of JTPA programs. An…

  12. Urban School Administration.

    ERIC Educational Resources Information Center

    McKelvey, Troy V., Ed.; Swanson, Austin D., Ed.

    This document contains 12 papers presented at an institute for urban school administrators designed to deal with the contemporary urban educational problems incident to school desegregation, social integration, and the equality of educational opportunity. The authors of the papers relate recent research findings to practical field experience, and…

  13. Telecommunications administration standard

    SciTech Connect

    Gustwiller, K.D.

    1996-05-01

    The administration of telecommunications is critical to proper maintenance and operation. The intent is to be able to properly support telecommunications for the distribution of all information within a building/campus. This standard will provide a uniform administration scheme that is independent of applications, and will establish guidelines for owners, installers, designers and contractors. This standard will accommodate existing building wiring, new building wiring and outside plant wiring. Existing buildings may not readily adapt to all applications of this standard, but the requirement for telecommunications administration is applicable to all buildings. Administration of the telecommunications infrastructure includes documentation (labels, records, drawings, reports, and work orders) of cables, termination hardware, patching and cross-connect facilities, telecommunications rooms, and other telecommunications spaces (conduits, grounding, and cable pathways are documented by Facilities Engineering). The investment in properly documenting telecommunications is a worthwhile effort. It is necessary to adhere to these standards to ensure quality and efficiency for the operation and maintenance of the telecommunications infrastructure for Sandia National Laboratories.

  14. Hospital Library Administration.

    ERIC Educational Resources Information Center

    Cramer, Anne

    The objectives of a hospital are to improve patient care, while the objectives of a hospital library are to improve services to the staff which will support their efforts. This handbook dealing with hospital administration is designed to aid the librarian in either implementing a hospital library, or improving services in an existing medical…

  15. Administrative Salary Summary Data.

    ERIC Educational Resources Information Center

    Colorado Commission on Higher Education, Denver.

    This report presents salary data on selected administrative positions from all public higher education institutions, governing boards, and other higher education state-level agencies in Colorado. Table 1 presents, by institutional type, the median and mean salaries for 1994-95, as well as the frequency and range of salaries, for the following…

  16. A Treatise on Administration.

    ERIC Educational Resources Information Center

    Moore, Thomas R.

    1988-01-01

    Expands Henri Fayol's definition of the administrative process to include a humanistic approach involving planning, organizing, implementing, controlling, evaluating, and satisfying functions. This empirical definition differs from some theoretical approaches by looking beyond resource consumption to consider ecological effects on the environment…

  17. Guidebook for School Administrators.

    ERIC Educational Resources Information Center

    Hess, Fritz, Ed.

    To provide guidance and advice regarding day-to-day responsibilities of new and experienced school administrators and superintendents in New York State, this compendium of knowledge and advice submitted by practitioners is presented with emphasis on all major aspects of superintendency. The section on general aspects of superintendency includes…

  18. Administrators Confront Student "Sexting"

    ERIC Educational Resources Information Center

    Manzo, Kathleen Kennedy

    2009-01-01

    Cellphone-savvy students have created instructional and disciplinary challenges for educators for years. But the recent emergence of "sexting" by adolescents over their mobile phones caught many school administrators off guard, and the practice is prompting efforts around the country to craft policy responses. Students' sharing of nude or…

  19. IVA: Improving Vocational Administration.

    ERIC Educational Resources Information Center

    EPD Consortium D, Richardson, TX.

    These six instructional units are intended to provide instructors of vocational education administration with a systematic package of materials for their programs of preservice and/or inservice instruction and to provide materials which could be reproduced for learner use. These units cover the following subject matter: (1) federal legislation…

  20. Administrative Utility Analysis: Appendices.

    ERIC Educational Resources Information Center

    Peat, Marwick, Mitchell and Co., San Juan, Puerto Rico.

    Appendixes to a study on administrative utility analysis and vocational education programs for the Area of Vocational and Technical Education (AVTE) in the Puerto Rico Department of Education contain the planning and budgeting system elements, position descriptions, and information on the growth of vocational education in Puerto Rico. The elements…

  1. Standards and Administration.

    ERIC Educational Resources Information Center

    Gross, S. P.

    1978-01-01

    Presents a literature review of water quality standards and administration, covering publications of 1976-77. Consideration is given to municipal facilities, National Pollutant Discharge Elimination Systems, regional and international water quality management, and effluent standards. A list of 99 references is also presented. (HM)

  2. Research Administration: Lessons Learned.

    ERIC Educational Resources Information Center

    Dummer, George H.

    1995-01-01

    The ways in which accountability issues have affected federal-university relationships, particularly in the area of academic research, are examined. Lessons university administrators have learned since issuance of Office of Management and Budget Circular A-21 in 1958, Congressional hearings on the operations of the National Institutes of Health…

  3. Educational Administration's Weber.

    ERIC Educational Resources Information Center

    Gronn, Peter

    1994-01-01

    Discusses Max Weber's importance in Greenfield's work, particularly in Greenfield and Ribbins'"Greenfield on Educational Administration" (1993). In concentrating on human actors' subjective understanding, Greenfield was a faithful Weberian. However, he deviated from Weber by disavowing structural explanations of social and organizational…

  4. Administrative Uses of Microcomputers.

    ERIC Educational Resources Information Center

    Crawford, Chase

    1987-01-01

    This paper examines the administrative uses of the microcomputer, stating that high performance educational managers are likely to have microcomputers in their organizations. Four situations that would justify the use of a computer are: (1) when massive amounts of data are processed through well-defined operations; (2) when data processing is…

  5. Educator Effectiveness Administrative Manual

    ERIC Educational Resources Information Center

    Pennsylvania Department of Education, 2014

    2014-01-01

    The goal of this manual is to provide guidance in the evaluation of educators, highlight critical components of effectiveness training, and offer opportunities for professional growth. The term "educator" includes teachers, all professional and temporary professional employees, education specialists, and school administrators/principals.…

  6. Discretionary Grants Administration Manual.

    ERIC Educational Resources Information Center

    Office of Human Development Services (DHHS), Washington, DC.

    This manual sets forth applicable administrative policies and procedures to recipients of discretionary project grants or cooperative agreements awarded by program offices in the Office of Human Development Services (HDS). It is intended to serve as a basic reference for project directors and business officers of recipient organizations who are…

  7. Study Shows Administrative Shortage.

    ERIC Educational Resources Information Center

    Sullivan, John R., Jr.

    1989-01-01

    Summarizes "Administrative Shortage in New England: The Evidence, the Causes, the Recommendations." High pressure, long hours, low salaries, and high housing costs are among the reasons cited for the shortage. Recommendations are centered on role identity, staff support, training, and recruitment. (SI)

  8. Professionalism in Educational Administration.

    ERIC Educational Resources Information Center

    Silver, Paula F.

    That the quest for a general theory of educational administration has been a misdirection of effort and that the advancement of professionalism within this field would represent a more sensible endeavor for the production of useful knowledge is the focus of this essay. The advancement of professionalism would entail a reorientation of research…

  9. Public Relations for Administrators.

    ERIC Educational Resources Information Center

    Bagin, Don; And Others

    This volume provides information and recommendations about public relations to assist school administrators in developing effective communication. The document contains 15 chapters. "The Scope of Public Relations," chapter 1, specifies characteristics of and individuals responsible for an effective program. Chapter 2, "Personal Public Relations,"…

  10. Championing the Latino Administrator

    ERIC Educational Resources Information Center

    Garcia, Carlos A.

    2011-01-01

    When the author worked as a vice principal at a K-8 school in Watsonville, California, a school predominantly filled with migrant workers' children, he felt a lack of support as a Latino as he began moving up into school administration. He also continued to see what he had seen as a teacher--which was how underserved minority students were. These…

  11. Indicators of Administrative Effectiveness.

    ERIC Educational Resources Information Center

    Skipper, Charles E.; Hofmann, Richard J.

    Ten personal characteristics and seven administrative skills that differentiated effective from ineffective university leaders were assessed by multiple discriminate analysis. The personal characteristics identified by previous research (Skipper, 1975, 1977) are: responsibility, integrity, self-control, intellectual efficiency, flexibility,…

  12. Migrant Education Administrative Handbook.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Bureau of Migrant Education.

    Intended to provide information pertaining to the administration of migrant education projects in Louisiana, the handbook is divided into two sections: basic guidelines for program operations and support services--nursing. Section I covers the Federal and State migrant program, local migrant projects, project personnel and staff development, and…

  13. Redis database administration tool

    SciTech Connect

    Martinez, J. J.

    2013-02-13

    MyRedis is a product of the Lorenz subproject under the ASC Scirntific Data Management effort. MyRedis is a web based utility designed to allow easy administration of instances of Redis databases. It can be usedd to view and manipulate data as well as run commands directly against a variety of different Redis hosts.

  14. Renaissance Administrator, Spring 1998.

    ERIC Educational Resources Information Center

    Dowdy, June P., Ed.

    1998-01-01

    This spring 1998 issue of Renaissance Administrator features the following articles: (1) "Servant Leadership and Higher Education--What is Leadership?" (Richard E. Hasselbach); (2) "Teaching Writing in the 90's--Carnivorous Printers and Dying Grandmothers" (Helen Ruggieri); (3) Assignment--Journal Writing" (Lynn Muscato); and (4) "A Business…

  15. Intrathecal administration of iopamidol in children: clinical and diagnostic results.

    PubMed

    Wells, R G; Seidel, F G; Sty, J R; Swick, H M

    1988-01-01

    An open label, noncomparative clinical trial of intrathecal iopamidol in children was performed. Sixty-one subjects between the ages of 24 days and 17 years were studied. Opacification of the subarachnoid space was adequate in all cases. Mild adverse reactions were detected in 10% of the participants. Seizures, EEG alterations or other severe reactions did not occur. The findings confirm the efficacy and safety of iopamidol as an intrathecal contrast medium in pediatrics.

  16. Hospital administrative characteristics and volunteer resource management practices.

    PubMed

    Intindola, Melissa; Rogers, Sean; Flinchbaugh, Carol; Della Pietra, Doug

    2016-05-16

    Purpose - The purpose of this paper is to explore the links between various characteristics of hospital administration and the utilization of classes of volunteer resource management (VRM) practices. Design/methodology/approach - This paper uses original data collected via surveys of volunteer directors in 122 hospitals in five Northeastern and Southern US states. Findings - Structural equation modeling results suggest that number of paid volunteer management staff, scope of responsibility of the primary volunteer administrator, and hospital size are positively associated with increased usage of certain VRM practices. Research limitations/implications - First, the authors begin the exploration of VRM antecedents, and encourage others to continue this line of inquiry; and second, the authors assess dimensionality of practices, allowing future researchers to consider whether specific dimensions have a differential impact on key individual and organizational outcomes. Practical implications - Based on the findings of a relationship between administrative characteristics and the on-the-ground execution of VRM practice, a baseline audit comparing current practices to those VRM practices presented here might be useful in determining what next steps may be taken to focus investments in VRM that can ultimately drive practice utilization. Originality/value - The exploration of the dimensionality of volunteer management adds a novel perspective to both the academic study, and practice, of volunteer management. To the authors' knowledge, this is the first empirical categorization of VRM practices. PMID:27119392

  17. Hospital administrative characteristics and volunteer resource management practices.

    PubMed

    Intindola, Melissa; Rogers, Sean; Flinchbaugh, Carol; Della Pietra, Doug

    2016-05-16

    Purpose - The purpose of this paper is to explore the links between various characteristics of hospital administration and the utilization of classes of volunteer resource management (VRM) practices. Design/methodology/approach - This paper uses original data collected via surveys of volunteer directors in 122 hospitals in five Northeastern and Southern US states. Findings - Structural equation modeling results suggest that number of paid volunteer management staff, scope of responsibility of the primary volunteer administrator, and hospital size are positively associated with increased usage of certain VRM practices. Research limitations/implications - First, the authors begin the exploration of VRM antecedents, and encourage others to continue this line of inquiry; and second, the authors assess dimensionality of practices, allowing future researchers to consider whether specific dimensions have a differential impact on key individual and organizational outcomes. Practical implications - Based on the findings of a relationship between administrative characteristics and the on-the-ground execution of VRM practice, a baseline audit comparing current practices to those VRM practices presented here might be useful in determining what next steps may be taken to focus investments in VRM that can ultimately drive practice utilization. Originality/value - The exploration of the dimensionality of volunteer management adds a novel perspective to both the academic study, and practice, of volunteer management. To the authors' knowledge, this is the first empirical categorization of VRM practices.

  18. Detector decoy quantum key distribution

    NASA Astrophysics Data System (ADS)

    Moroder, Tobias; Curty, Marcos; Lütkenhaus, Norbert

    2009-04-01

    Photon number resolving detectors can enhance the performance of many practical quantum cryptographic setups. In this paper, we employ a simple method to estimate the statistics provided by such a photon number resolving detector using only a threshold detector together with a variable attenuator. This idea is similar in spirit to that of the decoy state technique, and is especially suited to those scenarios where only a few parameters of the photon number statistics of the incoming signals have to be estimated. As an illustration of the potential applicability of the method in quantum communication protocols, we use it to prove security of an entanglement-based quantum key distribution scheme with an untrusted source without the need for a squash model and by solely using this extra idea. In this sense, this detector decoy method can be seen as a different conceptual approach to adapt a single-photon security proof to its physical, full optical implementation. We show that in this scenario, the legitimate users can now even discard the double click events from the raw key data without compromising the security of the scheme, and we present simulations on the performance of the BB84 and the 6-state quantum key distribution protocols.

  19. Spatial synchronization using watermark key structure

    NASA Astrophysics Data System (ADS)

    Lin, Eugene T.; Delp, Edward J., III

    2004-06-01

    Recently, we proposed a method for constructing a template for efficient temporal synchronization in video watermarking. Our temporal synchronization method uses a state machine key generator for producing the watermark embedded in successive frames of video. A feature extractor allows the watermark key schedule to be content dependent, increasing the difficulty of copy and ownership attacks. It was shown that efficient synchronization can be achieved by adding temporal redundancy into the key schedule. In this paper, we explore and extend the concepts of our temporal synchronization method to spatial synchronization. The key generator is used to construct the embedded watermark of non-overlapping blocks of the video, creating a tiled structure. The autocorrelation of the tiled watermark contains local maxima or peaks with a grid-like structure, where the distance between the peaks indicates the scale of the watermark and the orientation of the peaks indicate the watermark rotation. Experimental results are obtained using digital image watermarks. Scaling and rotation attacks are investigated.

  20. 41 CFR Appendix A to Subpart E of... - 3-Key Points and Principles

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Academy of Sciences or the National Academy of Public Administration? Pt. 102-3, Subpt. E, App. A Appendix... (NAS) and the National Academy of Public Administration (NAPA) to adopt separate procedures for... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false 3-Key Points...

  1. Ares Knowledge Capture: Summary and Key Themes Presentation

    NASA Technical Reports Server (NTRS)

    Coates, Ralph H.

    2011-01-01

    This report has been developed by the National Aeronautics and Space Administration (NASA) Human Exploration and Operations Mission Directorate (HEOMD) Risk Management team in close coordination with the MSFC Chief Engineers Office. This document provides a point-in-time, cumulative, summary of actionable key lessons learned derived from the design project. Lessons learned invariably address challenges and risks and the way in which these areas have been addressed. Accordingly the risk management thread is woven throughout the document.

  2. Performance of device-independent quantum key distribution

    NASA Astrophysics Data System (ADS)

    Cao, Zhu; Zhao, Qi; Ma, Xiongfeng

    2016-07-01

    Quantum key distribution provides information-theoretically-secure communication. In practice, device imperfections may jeopardise the system security. Device-independent quantum key distribution solves this problem by providing secure keys even when the quantum devices are untrusted and uncharacterized. Following a recent security proof of the device-independent quantum key distribution, we improve the key rate by tightening the parameter choice in the security proof. In practice where the system is lossy, we further improve the key rate by taking into account the loss position information. From our numerical simulation, our method can outperform existing results. Meanwhile, we outline clear experimental requirements for implementing device-independent quantum key distribution. The maximal tolerable error rate is 1.6%, the minimal required transmittance is 97.3%, and the minimal required visibility is 96.8 % .

  3. 7. Administrative structures.

    PubMed

    2014-05-01

    The basic systems of any society rarely can operate independently. Instead, they are dependent and often interdependent upon other entities. Such entities control the resources within their respective systems. Thus, coordination and control agencies require contracts or memoranda of understanding with these entities in order to assure access to the resources required during a crisis. These administrative structures include: (1) governmental institutions and agencies, including the military; (2) intergovernmental organisations; (3) nongovernmental organisations; (4) commercial private sector organisations; and (5) academic institutions. These dependencies create potential barriers to the provision of coordination and control including: (1) the complexity of the administrative structures with which coordination and control must interact; (2) the location of resources; (3) finding responsible person(s); (4) the competence and compatibility; (5) methods of access; (6) payment; (7) contracts and memoranda of understanding; (8) inventories of accessible resources; (9) competition for the mandate, power, and resources; and (10) jealousy. The need for potential interactions between administrative structures requires that agreements for the sharing of resources during crises be reached as part of planning and preparedness. Gaining an understanding of these relationships is an important area for research.

  4. Quantum key distribution with dual detectors

    SciTech Connect

    Qi, Bing; Zhao, Yi; Ma, Xiongfeng; Lo, Hoi-Kwong; Qian, Li

    2007-05-15

    To improve the performance of a quantum-key-distribution (QKD) system, high speed, low dark count single photon detectors (or low-noise homodyne detectors) are required. However, in practice, a fast detector is usually noisy. Here, we propose a dual-detector method to improve the performance of a practical QKD system with realistic detectors: the legitimate receiver randomly uses either a fast (but noisy) detector or a quiet (but slow) detector to measure the incoming quantum signals. The measurement results from the quiet detector can be used to bound the eavesdropper's information, while the measurement results from the fast detector are used to generate a secure key. We apply this idea to various QKD protocols. Simulation results demonstrate significant improvements of the secure key rate in the lower loss regime in both Bennett-Brassard 1984 (BB84) protocol with ideal single photon source and Gaussian-modulated coherent states protocol; while for decoy-state BB84 protocol with weak coherent source, the improvement is moderate. We also discuss various practical issues in implementing the dual-detector scheme.

  5. Key paediatric messages from Amsterdam

    PubMed Central

    Barben, Jürg; Bohlin, Kajsa; Everard, Mark L.; Hall, Graham; Pijnenburg, Mariëlle; Priftis, Kostas N.; Rusconi, Franca; Midulla, Fabio

    2016-01-01

    The Paediatric Assembly of the European Respiratory Society (ERS) maintained its high profile at the 2015 ERS International Congress in Amsterdam. There were symposia on preschool wheeze, respiratory sounds and cystic fibrosis; an educational skills workshop on paediatric respiratory resuscitation; a hot topic session on risk factors and early origins of respiratory diseases; a meet the expert session on paediatric lung function test reference values; and the annual paediatric grand round. In this report the Chairs of the Paediatric Assembly's Groups highlight the key messages from the abstracts presented at the Congress. PMID:27730186

  6. One-way quantum key distribution: Simple upper bound on the secret key rate

    SciTech Connect

    Moroder, Tobias; Luetkenhaus, Norbert; Curty, Marcos

    2006-11-15

    We present a simple method to obtain an upper bound on the achievable secret key rate in quantum key distribution (QKD) protocols that use only unidirectional classical communication during the public-discussion phase. This method is based on a necessary precondition for one-way secret key distillation; the legitimate users need to prove that there exists no quantum state having a symmetric extension that is compatible with the available measurements results. The main advantage of the obtained upper bound is that it can be formulated as a semidefinite program, which can be efficiently solved. We illustrate our results by analyzing two well-known qubit-based QKD protocols: the four-state protocol and the six-state protocol.

  7. Public/private key certification authority and key distribution. Draft

    SciTech Connect

    Long, J.P.; Christensen, M.J.; Sturtevant, A.P.; Johnston, W.E.

    1995-09-25

    Traditional encryption, which protects messages from prying eyes, has been used for many decades. The present concepts of encryption are built from that heritage. Utilization of modern software-based encryption techniques implies much more than simply converting files to an unreadable form. Ubiquitous use of computers and advances in encryption technology coupled with the use of wide-area networking completely changed the reasons for utilizing encryption technology. The technology demands a new and extensive infrastructure to support these functions. Full understanding of these functions, their utility and value, and the need for an infrastructure, takes extensive exposure to the new paradigm. This paper addresses issues surrounding the establishment and operation of a key management system (i.e., certification authority) that is essential to the successful implementation and wide-spread use of encryption.

  8. Measurement-device-independent quantum key distribution.

    PubMed

    Lo, Hoi-Kwong; Curty, Marcos; Qi, Bing

    2012-03-30

    How to remove detector side channel attacks has been a notoriously hard problem in quantum cryptography. Here, we propose a simple solution to this problem--measurement-device-independent quantum key distribution (QKD). It not only removes all detector side channels, but also doubles the secure distance with conventional lasers. Our proposal can be implemented with standard optical components with low detection efficiency and highly lossy channels. In contrast to the previous solution of full device independent QKD, the realization of our idea does not require detectors of near unity detection efficiency in combination with a qubit amplifier (based on teleportation) or a quantum nondemolition measurement of the number of photons in a pulse. Furthermore, its key generation rate is many orders of magnitude higher than that based on full device independent QKD. The results show that long-distance quantum cryptography over say 200 km will remain secure even with seriously flawed detectors.

  9. Measurement-device-independent quantum key distribution.

    PubMed

    Lo, Hoi-Kwong; Curty, Marcos; Qi, Bing

    2012-03-30

    How to remove detector side channel attacks has been a notoriously hard problem in quantum cryptography. Here, we propose a simple solution to this problem--measurement-device-independent quantum key distribution (QKD). It not only removes all detector side channels, but also doubles the secure distance with conventional lasers. Our proposal can be implemented with standard optical components with low detection efficiency and highly lossy channels. In contrast to the previous solution of full device independent QKD, the realization of our idea does not require detectors of near unity detection efficiency in combination with a qubit amplifier (based on teleportation) or a quantum nondemolition measurement of the number of photons in a pulse. Furthermore, its key generation rate is many orders of magnitude higher than that based on full device independent QKD. The results show that long-distance quantum cryptography over say 200 km will remain secure even with seriously flawed detectors. PMID:22540686

  10. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Requirements for storing and using a private key for digitally signing orders. 1311.30 Section 1311.30 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION... private key. (b) The certificate holder must provide FIPS-approved secure storage for the private key,...

  11. 77 FR 72825 - Narrow Woven Ribbons With Woven Selvedge From Taiwan: Final Results of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... International Trade Administration Narrow Woven Ribbons With Woven Selvedge From Taiwan: Final Results of Antidumping Duty Administrative Review; 2010-2011 AGENCY: Import Administration, International Trade... Administration, International Trade Administration, U.S. Department of Commerce, 14th Street and...

  12. A Novel Re-keying Function Protocol (NRFP) For Wireless Sensor Network Security

    PubMed Central

    Abdullah, Maan Younis; Hua, Gui Wei; Alsharabi, Naif

    2008-01-01

    This paper describes a novel re-keying function protocol (NRFP) for wireless sensor network security. A re-keying process management system for sensor networks is designed to support in-network processing. The design of the protocol is motivated by decentralization key management for wireless sensor networks (WSNs), covering key deployment, key refreshment, and key establishment. NRFP supports the establishment of novel administrative functions for sensor nodes that derive/re-derive a session key for each communication session. The protocol proposes direct connection, in-direct connection and hybrid connection. NRFP also includes an efficient protocol for local broadcast authentication based on the use of one-way key chains. A salient feature of the authentication protocol is that it supports source authentication without precluding innetwork processing. Security and performance analysis shows that it is very efficient in computation, communication and storage and, that NRFP is also effective in defending against many sophisticated attacks.

  13. Key Questions on the Obama Administration's 2013 Education Budget Request: Federal Education Budget Project. Issue Brief

    ERIC Educational Resources Information Center

    New America Foundation, 2012

    2012-01-01

    President Barack Obama submitted his third budget request to Congress on February 13th, 2012. The budget request includes proposed funding levels for all federal programs and agencies in aggregate for the upcoming 10 fiscal years, and specific fiscal year 2013 funding levels for programs subject to the annual appropriations process. It is…

  14. Teachers' Expectations and School Administration: Keys of Better Communication in Schools

    ERIC Educational Resources Information Center

    Aslanargun, Engin

    2015-01-01

    Problem Statement: The quality of education carried out in schools depends largely on the performance of teachers and school principals in cooperation. It is possible to say that a qualified education of students depends on the performance and compliance degree of these two groups. In this process, teachers' having the primary responsibility for…

  15. Demonstrating the value of antimicrobial stewardship programs to hospital administrators.

    PubMed

    Nagel, Jerod L; Stevenson, James G; Eiland, Edward H; Kaye, Keith S

    2014-10-15

    The movement away from fee-for-service models to those that emphasize quality of care and patient outcomes affords a unique opportunity for antimicrobial stewardship programs to expand their value for hospital administration. Antimicrobial stewardship participants must collaborate with administrators and key stakeholders to position themselves to improve economic, process, and outcomes measures. This will allow the establishment of antimicrobial stewardship programs as essential components of the present and future healthcare quality journey.

  16. Economic perspectives on key issues

    SciTech Connect

    Johnson, P.; Thomas, B.

    1985-01-01

    This book is about the contribution that economics can make to the understanding of some of today's key issues. The twelve topics discussed are representative of a very wide range of concerns. The first three chapters (on nuclear deterrence, the Palestinian problem, and sanctions against South Africa) are all issues associated with international relations. Later chapters consider the environment, poverty, technology, and the role of government. Family, crime, comprehensive education and youth unemployment issues are also addressed. All of the topics included illustrate issues which are of concern to many different societies. However, it is important to examine these issues in specific contexts rather than to rely on a purely general treatment using stylised facts. In a number of chapters the issues are therefore presented in the context of the UK and sometimes particular case studies are discussed.

  17. Astrocytes: Key Regulators of Neuroinflammation.

    PubMed

    Colombo, Emanuela; Farina, Cinthia

    2016-09-01

    Astrocytes are crucial regulators of innate and adaptive immune responses in the injured central nervous system. Depending on timing and context, astrocyte activity may exacerbate inflammatory reactions and tissue damage, or promote immunosuppression and tissue repair. Recent literature has unveiled key factors and intracellular signaling pathways that govern astrocyte behavior during neuroinflammation. Here we have re-visited in vivo studies on astrocyte signaling in neuroinflammatory models focusing on evidences obtained from the analysis of transgenic mice where distinct genes involved in ligand binding, transcriptional regulation and cell communication have been manipulated in astrocytes. The integration of in vivo observations with in vitro data clarifies precise signaling steps, highlights the crosstalk among pathways and identifies shared effector mechanisms in neuroinflammation.

  18. Key aspects of coronal heating

    NASA Astrophysics Data System (ADS)

    Klimchuk, James A.

    2015-04-01

    We highlight 10 key aspects of coronal heating that must be understood before we can consider the problem to be solved. (1) All coronal heating is impulsive. (2) The details of coronal heating matter. (3) The corona is filled with elemental magnetic stands. (4) The corona is densely populated with current sheets. (5) The strands must reconnect to prevent an infinite build-up of stress. (6) Nanoflares repeat with different frequencies. (7) What is the characteristic magnitude of energy release? (8) What causes the collective behaviour responsible for loops? (9) What are the onset conditions for energy release? (10) Chromospheric nanoflares are not a primary source of coronal plasma. Significant progress in solving the coronal heating problem will require coordination of approaches: observational studies, field-aligned hydrodynamic simulations, large-scale and localized three-dimensional magnetohydrodynamic simulations, and possibly also kinetic simulations. There is a unique value to each of these approaches, and the community must strive to coordinate better.

  19. Key Aspects of Coronal Heating

    NASA Astrophysics Data System (ADS)

    Klimchuk, James A.

    2015-04-01

    We highlight ten key aspects of coronal heating that must be understood before we can consider the problem to be solved. (1) All coronal heating is impulsive. (2) The details of coronal heating matter. (3) The corona is filled with elemental magnetic stands. (4) The corona is densely populated with current sheets. (5) The strands must reconnect to prevent an infinite buildup of stress. (6) Nanoflares repeat with different frequencies. (7) What is the characteristic magnitude of energy release? (8) What causes the collective behavior responsible for loops? (9) What are the onset conditions for energy release? (10) Chromospheric nanoflares are not a primary source of coronal plasma. Significant progress in solving the coronal heating problem will require a coordination of approaches: observational studies, field-aligned hydrodynamic simulations, large-scale and localized 3D MHD simulations, and possibly also kinetic simulations. There is a unique value to each of these approaches, and the community must strive to coordinate better.

  20. Administration of Educational Services: A Glossary of Basic Administration Terminology.

    ERIC Educational Resources Information Center

    Wheelbarger, J. J.

    From "achievement motivation" and "administration" to "Theory Z" and "viscidity and hedonic tone," this glossary defines 87 terms as they are used in educational administration. The terms include philosophical, psychological, organizational, and social concepts, but they all are employed in the theory and practice of administration. A short…

  1. The Efficacy of Administrator Preparation Programs: Private School Administrators' Attitudes.

    ERIC Educational Resources Information Center

    Hughes, H. Woodrow; Johnson, Ruth N.; Madjidi, Farzin

    This report examines divergent views that may exist among administrators based on administrators' demographic characteristics and how these differences affect curriculum design for this group. It looks at factors, such as the person's age, gender, and ethnicity, that might have influenced whether or not an administrator completed a…

  2. A Review of the Literature on College Administrators and Administrations.

    ERIC Educational Resources Information Center

    Nash, George; Uhse, Stefan

    A review of the extensive literature on college administration and college administrators reveals there are relatively few empirical studies in the field. It was also observed that: there is widespread agreement on a few broad principles; there has been a heavy emphasis on human relations and proper administrative procedures; there are fundamental…

  3. Tools For Installing Keys On A Stud

    NASA Technical Reports Server (NTRS)

    Goodoak, Robert D.

    1995-01-01

    Two tools designed to be used together to drive long locking keys axially to install them on stud. Tools are: supporter holding keys in correct relative alignment and driver having multiple prongs, each of which fits into one of holes in supporter. Tools prevent bending and breaking of keys during installation, and make possible to install all keys simultaneously, in one motion.

  4. NOAA administrator reviews agency progress and challenges

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-12-01

    The approach of the new year is a traditional time to tally up successes, failures, and the path ahead. Jane Lubchenco, administrator of the U.S. National Oceanic and Atmospheric Administration (NOAA), examined some agency advances and significant challenges during the 7 December Union Agency Lecture at the AGU Fall Meeting, during a press briefing, and in an interview with Eos. Lubchenco focused on several key areas including the concern about monitoring, mitigating, and managing extreme events; budgetary pressures the agency faces in current fiscal year (FY) 2012 and in FY 2013, with President Barack Obama on 18 November having signed into law a bill, HR 2112, following congressional agreement on a budget legislation conference report; and NOAA's newly released scientific integrity policy (see "NOAA issues scientific integrity policy," Eos Trans. AGU, 92(50), 467, doi:10.1029/2011EO500004, 2011).

  5. Continuous-variable quantum key distribution with noisy coherent states

    SciTech Connect

    Filip, Radim

    2008-02-15

    An excess noise in coherent-state preparation can prevent secure key distribution through lossy channel. The feasible single-copy and multicopy linear optical methods are proposed to purify the prepared state. The single-copy method always sufficiently reduces the excess noise to obtain the key secure against both the individual and collective attacks even through any lossy channel. To increase the secure key rate, two feasible applications of the multicopy linear optical purification are proposed. As a result, maximal secure key rate achievable through a given lossy channel can be approached.

  6. SLAR image interpretation keys for geographic analysis

    NASA Technical Reports Server (NTRS)

    Coiner, J. C.

    1972-01-01

    A means for side-looking airborne radar (SLAR) imagery to become a more widely used data source in geoscience and agriculture is suggested by providing interpretation keys as an easily implemented interpretation model. Interpretation problems faced by the researcher wishing to employ SLAR are specifically described, and the use of various types of image interpretation keys to overcome these problems is suggested. With examples drawn from agriculture and vegetation mapping, direct and associate dichotomous image interpretation keys are discussed and methods of constructing keys are outlined. Initial testing of the keys, key-based automated decision rules, and the role of the keys in an information system for agriculture are developed.

  7. A novel key management scheme using biometrics

    NASA Astrophysics Data System (ADS)

    Sui, Yan; Yang, Kai; Du, Yingzi; Orr, Scott; Zou, Xukai

    2010-04-01

    Key management is one of the most important issues in cryptographic systems. Several important challenges in such a context are represented by secure and efficient key generation, key distribution, as well as key revocation. Addressing such challenges requires a comprehensive solution which is robust, secure and efficient. Compared to traditional key management schemes, key management using biometrics requires the presence of the user, which can reduce fraud and protect the key better. In this paper, we propose a novel key management scheme using iris based biometrics. Our newly proposed scheme outperforms traditional key management schemes as well as some existing key-binding biometric schemes in terms of security, diversity and/or efficiency.

  8. Lessons from the Top: Administration.

    ERIC Educational Resources Information Center

    Rude, Ron

    1999-01-01

    A superintendent with 20-plus years' teaching experience in the district discusses with a "both sides of the fence" perspective issues of standards, teacher pay, training and compensation for board members, teacher/administrator relationship, and the administrator role. (MLF)

  9. Administrative Aspects of Human Experimentation.

    ERIC Educational Resources Information Center

    Irvine, George W.

    1992-01-01

    The following administrative aspects of scientific experimentation with human subjects are discussed: the definition of human experimentation; the distinction between experimentation and treatment; investigator responsibility; documentation; the elements and principles of informed consent; and the administrator's role in establishing and…

  10. Food irradiation: Key research needs

    SciTech Connect

    Morehouse, K.M. )

    1993-01-01

    Treatment of foods with ionizing radiation reduces microbial infection and insect infestations, inhibits sprouting, and delays maturation, thereby extending the shelf life of foods. The treatment of different types of foods with ionizing radiation for specific purposes is accepted in several countries, although it is prohibited in others. The US Food and Drug Administration has established regulations to allow the treatment of several different foods with ionizing radiation and has received petitions for the approval of radiation treatment of additional foods. When carried out according to established good manufacturing practices, food irradiation yields safe, wholesome foods. The irradiated product may be often chemically or microbiologically [open quotes]safer[close quotes] than the nonirradiated product. This paper presents several areas of scientific research in which more information would facilitate the expansion of this technology and points out major areas of concern. The question of the public acceptance of foods that have been treated with ionizing radiation is discussed only briefly in order to make the presentation complete.

  11. Answering Key Fuel Cycle Questions

    SciTech Connect

    Steven J. Piet; Brent W. Dixon; J. Stephen Herring; David E. Shropshire; Mary Lou Dunzik-Gougar

    2003-10-01

    The Advanced Fuel Cycle Initiative (AFCI) program has both “outcome” and “process” goals because it must address both waste already accumulating as well as completing the fuel cycle in connection with advanced nuclear power plant concepts. The outcome objectives are waste geological repository capacity and cost, energy security and sustainability, proliferation resistance, fuel cycle economics, and safety. The process objectives are readiness to proceed and adaptability and robustness in the face of uncertainties. A classic decision-making approach to such a multi-attribute problem would be to weight individual quantified criteria and calculate an overall figure of merit. This is inappropriate for several reasons. First, the goals are not independent. Second, the importance of different goals varies among stakeholders. Third, the importance of different goals is likely to vary with time, especially the “energy future.” Fourth, some key considerations are not easily or meaningfully quantifiable at present. Instead, at this point, we have developed 16 questions the AFCI program should answer and suggest an approach of determining for each whether relevant options improve meeting each of the program goals. We find that it is not always clear which option is best for a specific question and specific goal; this helps identify key issues for future work. In general, we suggest attempting to create as many win-win decisions (options that are attractive or neutral to most goals) as possible. Thus, to help clarify why the program is exploring the options it is, and to set the stage for future narrowing of options, we have developed 16 questions, as follows: · What are the AFCI program goals? · Which potential waste disposition approaches do we plan for? · What are the major separations, transmutation, and fuel options? · How do we address proliferation resistance? · Which potential energy futures do we plan for? · What potential external triggers do we

  12. Three Generations of Educational Administration.

    ERIC Educational Resources Information Center

    Sharpe, F. G.

    This paper compares two Australian educational administration texts published in 1963 to reflect critically on the radical changes that have occurred in educational administration in Australia since then. The books are "Headmasters for Better Schools," by Bassett, Crane, and Walker; and "Training the Administrator," by Cunningham and Radford. The…

  13. Straight Talk about School Administrators.

    ERIC Educational Resources Information Center

    Association of California School Administrators.

    In this report, the Association of California School Administrators examined some of the myths and misrepresentations about administration in California's public schools. Specifically, it examined the following five myths: (1) A lot of money that could be better spent in the classroom is being wasted on administration. (2) There are too many…

  14. Special Education Administration Training Program.

    ERIC Educational Resources Information Center

    Watherman, Richard F.; Hollingsworth, Sue Ann

    Presented are course materials from a competency based education program in special education administration. It is explained that the Special Education Administration Training Program (SEATP) is designed for continuing education of administrators. Materials are divided into three self contained curriculum areas: fiscal management, personnel…

  15. Administrators' Decisions about Resource Allocation

    ERIC Educational Resources Information Center

    Knight, William E.; Folkins, John W.; Hakel, Milton D.; Kennell, Richard P.

    2011-01-01

    Do academic administrators make decisions about resource allocation differently depending on the discipline receiving the funding? Does an administrator's academic identity influence these decisions? This study explored those questions with a sample of 1,690 academic administrators at doctoral-research universities. Participants used fictional…

  16. Certification of Financial Aid Administrators

    ERIC Educational Resources Information Center

    Peterson, Stacey A.

    2011-01-01

    The certification of financial aid administrators has been debated for over 37 years. A job satisfaction survey conducted by the National Association of Student Financial Aid Administrators (NASFAA, 2008a) revealed that college and university administrators' perceptions of the efficiency, effectiveness, and quality of the services provided by the…

  17. Burnout among Special Education Administrators: A Preliminary Study

    ERIC Educational Resources Information Center

    Carter, Susan J.

    2011-01-01

    Research on the extent of stress and burnout among special education administrators is not as well developed as research on the extent of stress and burnout among teachers. This study utilized the Maslach Burnout Inventory to determine levels of stress and burnout among administrators of special education. Results indicated administrators of…

  18. Administrators' Understanding and Use of Family-Centered Practices

    ERIC Educational Resources Information Center

    Mandell, Colleen J.; Murray, Mary M.

    2009-01-01

    Employing qualitative methods, administrators' understanding and use of family-centered practices were examined. Results indicate differences in role perceptions and service delivery based on their level of understanding. Administrators with a comprehensive understanding of family-centered practices, in comparison to administrators with limited or…

  19. Key aspects of coronal heating.

    PubMed

    Klimchuk, James A

    2015-05-28

    We highlight 10 key aspects of coronal heating that must be understood before we can consider the problem to be solved. (1) All coronal heating is impulsive. (2) The details of coronal heating matter. (3) The corona is filled with elemental magnetic stands. (4) The corona is densely populated with current sheets. (5) The strands must reconnect to prevent an infinite build-up of stress. (6) Nanoflares repeat with different frequencies. (7) What is the characteristic magnitude of energy release? (8) What causes the collective behaviour responsible for loops? (9) What are the onset conditions for energy release? (10) Chromospheric nanoflares are not a primary source of coronal plasma. Significant progress in solving the coronal heating problem will require coordination of approaches: observational studies, field-aligned hydrodynamic simulations, large-scale and localized three-dimensional magnetohydrodynamic simulations, and possibly also kinetic simulations. There is a unique value to each of these approaches, and the community must strive to coordinate better. PMID:25897094

  20. Key aspects of coronal heating

    PubMed Central

    Klimchuk, James A.

    2015-01-01

    We highlight 10 key aspects of coronal heating that must be understood before we can consider the problem to be solved. (1) All coronal heating is impulsive. (2) The details of coronal heating matter. (3) The corona is filled with elemental magnetic stands. (4) The corona is densely populated with current sheets. (5) The strands must reconnect to prevent an infinite build-up of stress. (6) Nanoflares repeat with different frequencies. (7) What is the characteristic magnitude of energy release? (8) What causes the collective behaviour responsible for loops? (9) What are the onset conditions for energy release? (10) Chromospheric nanoflares are not a primary source of coronal plasma. Significant progress in solving the coronal heating problem will require coordination of approaches: observational studies, field-aligned hydrodynamic simulations, large-scale and localized three-dimensional magnetohydrodynamic simulations, and possibly also kinetic simulations. There is a unique value to each of these approaches, and the community must strive to coordinate better. PMID:25897094

  1. "Having choices is the key".

    PubMed

    Ogunleye, B

    1996-08-01

    When Chief Bisi Ogunleye was appointed Nigeria's Minister of Agriculture, the US-educated daughter of a tribal chief still believed that most Nigerian farmers were men. As she traveled throughout the country fulfilling her role, she met a group of women who wanted to start a palm oil and casaba processing plant but lacked the means to get a start-up loan. Chief Ogunleye's efforts to get officials to issue a loan were ridiculed, so she asked her husband to allow her to donate part of her salary to the women. With the $45 from the chief, the women began business and within 3 months had 6 times the original amount. This money was used to help other 6 other women's groups start businesses. By 1985, these efforts were so successful that the chief resigned her government job and founded the Country Women's Association of Nigeria, which has been successful in helping women because it realizes that the most important key to empowerment is having choices.

  2. Finite-key security analysis of quantum key distribution with imperfect light sources

    SciTech Connect

    Mizutani, Akihiro; Curty, Marcos; Lim, Charles Ci Wen; Imoto, Nobuyuki; Tamaki, Kiyoshi

    2015-09-09

    In recent years, the gap between theory and practice in quantum key distribution (QKD) has been significantly narrowed, particularly for QKD systems with arbitrarily flawed optical receivers. The status for QKD systems with imperfect light sources is however less satisfactory, in the sense that the resulting secure key rates are often overly dependent on the quality of state preparation. This is especially the case when the channel loss is high. Very recently, to overcome this limitation, Tamaki et al proposed a QKD protocol based on the so-called 'rejected data analysis', and showed that its security in the limit of infinitely long keys is almost independent of any encoding flaw in the qubit space, being this protocol compatible with the decoy state method. Here, as a step towards practical QKD, we show that a similar conclusion is reached in the finite-key regime, even when the intensity of the light source is unstable. More concretely, we derive security bounds for a wide class of realistic light sources and show that the bounds are also efficient in the presence of high channel loss. Our results strongly suggest the feasibility of long distance provably secure communication with imperfect light sources.

  3. Finite-key security analysis of quantum key distribution with imperfect light sources

    DOE PAGES

    Mizutani, Akihiro; Curty, Marcos; Lim, Charles Ci Wen; Imoto, Nobuyuki; Tamaki, Kiyoshi

    2015-09-09

    In recent years, the gap between theory and practice in quantum key distribution (QKD) has been significantly narrowed, particularly for QKD systems with arbitrarily flawed optical receivers. The status for QKD systems with imperfect light sources is however less satisfactory, in the sense that the resulting secure key rates are often overly dependent on the quality of state preparation. This is especially the case when the channel loss is high. Very recently, to overcome this limitation, Tamaki et al proposed a QKD protocol based on the so-called 'rejected data analysis', and showed that its security in the limit of infinitelymore » long keys is almost independent of any encoding flaw in the qubit space, being this protocol compatible with the decoy state method. Here, as a step towards practical QKD, we show that a similar conclusion is reached in the finite-key regime, even when the intensity of the light source is unstable. More concretely, we derive security bounds for a wide class of realistic light sources and show that the bounds are also efficient in the presence of high channel loss. Our results strongly suggest the feasibility of long distance provably secure communication with imperfect light sources.« less

  4. Floodlight quantum key distribution: A practical route to gigabit-per-second secret-key rates

    NASA Astrophysics Data System (ADS)

    Zhuang, Quntao; Zhang, Zheshen; Dove, Justin; Wong, Franco N. C.; Shapiro, Jeffrey H.

    2016-07-01

    The channel loss incurred in long-distance transmission places a significant burden on quantum key distribution (QKD) systems: they must defeat a passive eavesdropper who detects all the light lost in the quantum channel and does so without disturbing the light that reaches the intended destination. The current QKD implementation with the highest long-distance secret-key rate meets this challenge by transmitting no more than one photon per bit [M. Lucamarini et al., Opt. Express 21, 24550 (2013), 10.1364/OE.21.024550]. As a result, it cannot achieve the Gbps secret-key rate needed for one-time pad encryption of large data files unless an impractically large amount of multiplexing is employed. We introduce floodlight QKD (FL-QKD), which floods the quantum channel with a high number of photons per bit distributed over a much greater number of optical modes. FL-QKD offers security against the optimum frequency-domain collective attack by transmitting less than one photon per mode and using photon-coincidence channel monitoring, and it is completely immune to passive eavesdropping. More importantly, FL-QKD is capable of a 2-Gbps secret-key rate over a 50-km fiber link, without any multiplexing, using available equipment, i.e., no new technology need be developed. FL-QKD achieves this extraordinary secret-key rate by virtue of its unprecedented secret-key efficiency, in bits per channel use, which exceeds those of state-of-the-art systems by two orders of magnitude.

  5. Community College Administrative Roles in Identifying Faculty for Future Management Positions: A Phenomenological Study of Retired Administrators

    ERIC Educational Resources Information Center

    Knirk, Brian Doyle

    2013-01-01

    The community college system is beginning to see waves of retirements at all levels of the administrative structure. These retirements, in conjunction with expected growth in administrative positions, will result in system-wide administrative vacancies. Community colleges not already seeking new leaders are likely to find themselves in the midst…

  6. Introduction strategies raise key questions.

    PubMed

    Finger, W R; Keller, S

    1995-09-01

    Key issues that must be considered before a new contraceptive is introduced center on the need for a trained provider to begin or terminate the method, its side effects, duration of use, method's ability to meet users' needs and preferences, and extra training or staff requirements. Logistics and economic issues to consider are identifying a dependable way of effectively supplying commodities, planning extra services needed for the method, and cost of providing the method. Each contraceptive method presents a different side effect pattern and burdens the service delivery setting differently. The strategy developed to introduce or expand the 3-month injectable Depo-Provera (DMPA) can be used for any method. It includes a needs assessment and addresses regulatory issues, service delivery policies and procedures, information and training, evaluation, and other concerns. Viet Nam's needs assessment showed that Norplant should not be introduced until the service delivery system becomes stronger. Any needs assessment for expansion of contraceptive services should cover sexually transmitted disease/HIV issues. A World Health Organization strategy helps officials identify the best method mix for local situations. Introductory strategies must aim to improve the quality of family planning programs and expand choices. Many begin by examining existing data and conducting interviews with policymakers, users, providers, and women's health advocates. Introductory programs for Norplant focus on provider training, adequate counseling and informed consent for users, and ready access to removal. They need a well-prepared service delivery infrastructure. The first phase of the DMPA introductory strategy for the Philippines comprised a social marketing campaign and DMPA introduction at public clinics in 10 pilot areas with strong service delivery. Successful AIDS prevention programs show that people tend to use barrier methods when they are available. USAID is currently studying

  7. Perspectives on Obesity Programs at Children's Hospitals: Insights From Senior Program Administrators

    PubMed Central

    Norwood, Victoria; Hampl, Sarah; Ferris, Michelle; Hibbeln, Trillium; Patterson, Kellee; Pomietto, Maureen; Hassink, Sandra

    2011-01-01

    OBJECTIVE: The obesity epidemic has resulted in an increasing number of children needing multidisciplinary obesity treatment. To meet this need, pediatric obesity programs have arisen, particularly in children's hospitals. In 2008, the National Association of Children's Hospitals and Related Institutions (NACHRI) convened FOCUS on a Fitter Future, a group drawn from NACHRI member institutions, to investigate the needs, barriers, and capacity-building in these programs. METHODS: Senior administrators of the 47 NACHRI member hospitals that completed an application to participate in the FOCUS group were invited to complete a Web-based survey. The survey targeted 4 key areas: (1) perceived value of the obesity program; (2) funding mechanisms; (3) administrative challenges; and (4) sustainability of the programs. RESULTS: Nearly three-quarters of the respondents reported that their obesity programs were integrated into their hospitals' strategic plans. Obesity programs added value to their institutions because the programs met the needs of patients and families (97%), met the needs of health care providers (91%), prevented future health problems in children (85%), and increased visibility in the community (79%). Lack of reimbursement (82%) and high operating costs (71%) were the most frequently cited challenges. Respondents most frequently identified demonstration of program effectiveness (79%) as a factor that is necessary for ensuring program sustainability. CONCLUSIONS: Hospital administrators view tackling childhood obesity as integral to their mission to care for children. Our results serve to inform hospital clinicians and administrators as they develop and implement sustainable pediatric obesity programs. PMID:21885650

  8. Cryptographic Key Management and Critical Risk Assessment

    SciTech Connect

    Abercrombie, Robert K

    2014-05-01

    The Department of Energy Office of Electricity Delivery and Energy Reliability (DOE-OE) CyberSecurity for Energy Delivery Systems (CSEDS) industry led program (DE-FOA-0000359) entitled "Innovation for Increasing CyberSecurity for Energy Delivery Systems (12CSEDS)," awarded a contract to Sypris Electronics LLC to develop a Cryptographic Key Management System for the smart grid (Scalable Key Management Solutions for Critical Infrastructure Protection). Oak Ridge National Laboratory (ORNL) and Sypris Electronics, LLC as a result of that award entered into a CRADA (NFE-11-03562) between ORNL and Sypris Electronics, LLC. ORNL provided its Cyber Security Econometrics System (CSES) as a tool to be modified and used as a metric to address risks and vulnerabilities in the management of cryptographic keys within the Advanced Metering Infrastructure (AMI) domain of the electric sector. ORNL concentrated our analysis on the AMI domain of which the National Electric Sector Cyber security Organization Resource (NESCOR) Working Group 1 (WG1) has documented 29 failure scenarios. The computational infrastructure of this metric involves system stakeholders, security requirements, system components and security threats. To compute this metric, we estimated the stakes that each stakeholder associates with each security requirement, as well as stochastic matrices that represent the probability of a threat to cause a component failure and the probability of a component failure to cause a security requirement violation. We applied this model to estimate the security of the AMI, by leveraging the recently established National Institute of Standards and Technology Interagency Report (NISTIR) 7628 guidelines for smart grid security and the International Electrotechnical Commission (IEC) 63351, Part 9 to identify the life cycle for cryptographic key management, resulting in a vector that assigned to each stakeholder an estimate of their average loss in terms of dollars per day of system

  9. KEY COMPARISON: Key comparison CCQM-K29: Anion calibration solutions: final report

    NASA Astrophysics Data System (ADS)

    Weber, Michael; Wüthrich, Jürg

    2006-01-01

    In this key comparison anion calibration solutions of chloride and phosphate were investigated. The contents of both solutions were about 1 g/kg relative to the anion mass. For the chloride comparison 10 participants provided results by the following three analytical techniques: coulometry, titrimetry and ion chromatography. The phosphate amount content was determined by 10 NMIs whereby the following 6 techniques were applied: ion chromatography, titrimetry, ICP-OES, gravimetry, UV-Vis and ion-exchange followed by coulometry. The following institutes participated in this key comparison: BAM and PTB (Germany) BNM-LNE (France) CENAM (Mexico) EMPA (Switzerland) GUM (Poland) INTEC (Chile) KRISS (Korea) NMIJ (Japan) NRCCRM (China) SMU (Slovakia) With one exception all results were found within the range of +/-0.25% with respect to the gravimetric value. The variability (RSD) of the results is below 0.1% for both the chloride and the phosphate solution (chloride without CENAM result). Compared to the pilot study CCQM-P32 the results of CCQM-K29 were significantly better. This is especially true for the phosphate comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  10. Key Working for Families with Young Disabled Children

    PubMed Central

    Carter, Bernie; Thomas, Megan

    2011-01-01

    For families with a disabled child, the usual challenges of family life can be further complicated by the need to access a wide range of services provided by a plethora of professionals and agencies. Key working aims to support children and their families in navigating these complexities ensuring easy access to relevant, high quality, and coordinated care. The aim of this paper is to explore the key worker role in relation to “being a key worker” and “having a key worker”. The data within this paper draw on a larger evaluation study of the Blackpool Early Support Pilot Programme. The qualitative study used an appreciative and narrative approach and utilised mixed methods (interviews, surveys and a nominal group workshop). Data were collected from 43 participants (parents, key workers, and other stakeholders). All stakeholders who had been involved with the service were invited to participate. In the paper we present and discuss the ways in which key working made a difference to the lives of children and their families. We also consider how key working transformed the perspectives of the key workers creating a deeper and richer understanding of family lives and the ways in which other disciplines and agencies worked. Key working contributed to the shift to a much more family-centred approach, and enhanced communication and information sharing between professionals and agencies improved. This resulted in families feeling more informed. Key workers acted in an entrepreneurial fashion, forging new relationships with families and between families and other stakeholders. Parents of young disabled children and their service providers benefited from key working. Much of the benefit accrued came from strong, relational, and social-professional networking which facilitated the embedding of new ways of working into everyday practice. Using an appreciative inquiry approach provided an effective and relevant way of engaging with parents, professionals, and other

  11. Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration

    PubMed Central

    Bulmer, AC; Coombes, JS; Blanchfield, JT; Toth, I; Fassett, RG; Taylor, SM

    2011-01-01

    BACKGROUND AND PURPOSE Bilirubin and biliverdin possess antioxidant and anti-inflammatory properties and their exogenous administration protects against the effects of inflammation and trauma in experimental models. Despite the therapeutic potential of bile pigments, little is known about their in vivo parenteral or enteral absorption after exogenous administration. This study investigated the absorption and pharmacokinetics of bile pigments after i.v., i.p. and intraduodenal (i.d.) administration in addition to their metabolism and routes of excretion. EXPERIMENTAL APPROACH Anaesthetized Wistar rats had their bile duct, jugular and portal veins cannulated. Bile pigments were infused and their circulating concentrations/biliary excretion were measured over 180 min. KEY RESULTS After i.v. administration of unconjugated bilirubin, biliverdin and bilirubin ditaurate, their plasma concentrations decreased exponentially over time. Subsequently, native and metabolized compounds appeared in the bile. When administered i.p., their absolute bioavailabilities equalled 14.0, 16.1 and 33.1%, respectively, and correspondingly 38, 28 and 34% of the same bile pigment doses were excreted in the bile. Administration of unconjugated bilirubin and bilirubin ditaurate i.d. increased their portal and systemic concentrations and their systemic bioavailability equalled 1.0 and 2.0%, respectively. Correspondingly, 2.7 and 4.6%, of the doses were excreted in the bile. Biliverdin was rapidly metabolized and these products were absorbed and excreted via the urine and bile. CONCLUSIONS AND IMPLICATIONS Bile pigment absorption from the peritoneal and duodenal cavities demonstrate new routes of administration for the treatment of inflammatory and traumatic pathology. Oral biliverdin administration may lead to the production of active metabolite that protect from inflammation/complement activation. PMID:21486273

  12. The Case for Quantum Key Distribution

    NASA Astrophysics Data System (ADS)

    Stebila, Douglas; Mosca, Michele; Lütkenhaus, Norbert

    Quantum key distribution (QKD) promises secure key agreement by using quantum mechanical systems. We argue that QKD will be an important part of future cryptographic infrastructures. It can provide long-term confidentiality for encrypted information without reliance on computational assumptions. Although QKD still requires authentication to prevent man-in-the-middle attacks, it can make use of either information-theoretically secure symmetric key authentication or computationally secure public key authentication: even when using public key authentication, we argue that QKD still offers stronger security than classical key agreement.

  13. Repeated post- or presession cocaine administration: roles of dose and fixed-ratio schedule.

    PubMed Central

    Pinkston, Jonathan W; Branch, Marc N

    2004-01-01

    Effects of repeated administration of cocaine to animals behaving under operant contingencies have depended on when the drug is given. Moderate doses given presession have generally led to a decrease in the drug's effect, an outcome usually referred to as tolerance. When these same doses have been given after sessions, the usual result has been no change or an increase in the drug's effects, with the latter usually referred to as sensitization. In the present study, repeated postsession administration of a relatively small dose of cocaine (3.0 or 5.6 mg/kg) to pigeons responding under a multiple fixed-ratio 5, fixed-ratio 100 schedule of food presentation generally resulted in tolerance to the rate-decreasing effects of the drug. When the same dose was given before sessions, little additional tolerance was observed, although some subjects showed further tolerance in the small-ratio component. A regimen of repeated postsession injection of larger (10.0-23.0 mg/kg) doses suppressed key pecking during the session; responding resumed following discontinuation of postsession administrations. Effects of postsession administration of cocaine, therefore, depended on the dose, with smaller doses leading to tolerance and larger ones to suppression of behavior during the session. Effects of postsession drug administration of either small or large doses were not related to whether effects of postsession drug were experienced mainly in the operant test chamber or in the pigeon's home cage. The results with large postsession doses are compatible with a view that the drug acted as a Pavlovian unconditional stimulus, with the session-related stimuli acting as a long-duration Pavlovian conditional stimulus. Tolerance following postsession administration of the smaller doses challenges the view that it depended on experiencing the drug's effects while the arranged reinforcement contingencies were in effect. PMID:15239491

  14. Intravenous Medication Administration in Intensive Care: Opportunities for Technological Solutions

    PubMed Central

    Moss, Jacqueline; Berner, Eta; Bothe, Olaf; Rymarchuk, Irina

    2008-01-01

    Medication administration errors have been shown to be frequent and serious. Error is particularly prevalent in highly technical specialties such as critical care. The purpose of this study was to describe the characteristics of intravenous medication administration in five intensive care units. These data were used within the context of a larger study to design information system decision support to decrease medication administration errors in these settings. Nurses were observed during the course of their work and their intravenous medication administration process, medication order source, references used, calculation method, number of medications prepared simultaneously, and any interruptions occurring during the preparation and delivery phases of the administration event were recorded. In addition, chart reviews of medication administration records were completed and nurses were asked to complete an anonymous drop-box questionnaire regarding their experiences with medication administration error. The results of this study are discussed in terms of potential informatics solutions for reducing medication administration error. PMID:18998790

  15. Retaining experts: administrators' views on retention incentives and older employees.

    PubMed

    Moon, Tara C; Beck, Susan; Laudicina, Rebecca J

    2014-01-01

    A survey of members of the American Society for Clinical Laboratory Science (ASCLS) in 2012 examined laboratory administrators' views on retention incentives and older Clinical Laboratory Professionals (CLP). Results indicated that retention strategies currently in place are not concordant with the ones CLP think are important. Further, with the exception of ergonomic equipment, administrators reported low feasibility for the workplace changes favored by practitioners. While all administrators attributed positive traits to older CLP, older administrators held more favorable views. Administrators perceived older CLP as productive, having a high level of technical skills and loyal. The combination of technical competence and work ethic make retention of older CLP attractive to laboratory administrators and advantageous for combatting workforce shortages. This study highlights the discordance between the retention incentives valued by CLP and those viewed as feasible by administrators. Findings should be used by administrators to refine incentive packages that better reflect the desires of CLP. PMID:25219073

  16. Enculturation, Not Alchemy: Professionalizing Novice Writing Program Administrators.

    ERIC Educational Resources Information Center

    Peters, Bradley

    1998-01-01

    Discusses a process of acculturation in three stages by which fledgling Writing Program Administrators can be transformed into change agents: (1) critically reading the program to locate key allies, potential advocates, and proven adversaries; (2) implementing changes on an infrastructural level to convert positive relations among colleagues into…

  17. Principles of Economics: Course Administrative Manual [And] Unit Study Guide.

    ERIC Educational Resources Information Center

    Barbour, G. Jeffrey

    This learning package is a three-semester-hour, independent-study course in principles of economics designed for postsecondary, external degree students. Keyed to the commercially published textbook "Economics Today" (San Francisco, CA: Canfield Press, 1975), the package consists of an administrator manual, a student manual, 14 audiotapes, and a…

  18. Institutional Image: The Concept and Implications for Administrative Action.

    ERIC Educational Resources Information Center

    Renihan, Frederick I; Renihan, Patrick J.

    1989-01-01

    Explores institutional image as a key to providing a philosophy and a logical foundation for school improvement efforts. Identifies two image dimensions (cosmetic and pastoral) and classifies five school types (synergistic, candy store, disaffected, monastic, and survivor), and discusses implications for administrative action. Includes three…

  19. Educational Administration and the Management of Knowledge: 1980 Revisited

    ERIC Educational Resources Information Center

    Bates, Richard

    2013-01-01

    This paper revisits the thesis of a 1980 paper that suggested a new approach to educational administration based upon the New Sociology of Education. In particular it updates answers to the six key questions asked by that paper: what counts as knowledge; how is what counts as knowledge organised; how is what counts as knowledge transmitted; how is…

  20. Mapping the literature of nursing administration

    PubMed Central

    Galganski, Carol J.

    2006-01-01

    Objectives: As part of Phase I of a project to map the literature of nursing, sponsored by the Nursing and Allied Health Resources Section of the Medical Library Association, this study identifies the core literature cited in nursing administration and the indexing services that provide access to the core journals. The results of this study will assist librarians and end users searching for information related to this nursing discipline, as well as database producers who might consider adding specific titles to their indexing services. Methods: Using the common methodology described in the overview article, five source journals for nursing administration were identified and selected for citation analysis over a three-year period, 1996 to 1998, to identify the most frequently cited titles according to Bradford's Law of Scattering. From this core of most productive journal titles, the bibliographic databases that provide the best access to these titles were identified. Results: Results reveal that nursing administration literature relies most heavily on journal articles and on those titles identified as core nursing administrative titles. When the indexing coverage of nine services is compared, PubMed/MEDLINE and CINAHL provide the most comprehensive coverage of this nursing discipline. Conclusions: No one indexing service adequately covers this nursing discipline. Researchers needing comprehensive coverage in this area must search more than one database to effectively research their projects. While PubMed/MEDLINE and CINAHL provide more coverage for this discipline than the other indexing services, none is sufficiently broad in scope to provide indexing of nursing, health care management, and medical literature in a single file. Nurse administrators using the literature to research current work issues need to review not only the nursing titles covered by CINAHL but should also include the major weekly medical titles, core titles in health care administration, and

  1. Harry Potter and the Dichotomous Key

    ERIC Educational Resources Information Center

    Crowther, David T.

    2003-01-01

    In this lesson, students use Bertie Bott's Every Flavor Beans--a "wild" candy written about in the Harry Potter books and now available in stores--to learn about classification and dichotomous keys. In these activities, students sort jelly beans according to a key and then construct a key for a "new" flavor of beans. Students then build on their…

  2. The Geology of the Florida Keys.

    ERIC Educational Resources Information Center

    Shinn, Eugene A.

    1988-01-01

    Describes some of the ancient geologic history of the Florida Keys from Key Largo to Key West including the effects of glaciers, sea level rise, reef distribution, spurs and grooves, backstepping and ecological zonation, growth rates and erosion. Predicts future changes in this area. (CW)

  3. Independence day explosion on lovers key.

    PubMed

    Harding, Brett A; Wolf, Barbara C

    2007-09-01

    The display of fireworks is a popular holiday celebration in the United States. Because injuries due to recreational fireworks-related explosions among private consumers are relatively common, the sale of fireworks is regulated by the federal government and is also limited by state and local laws. In contrast, because fireworks display companies are under tight safety regulations, explosions in the professional pyrotechnics industry are uncommon occurrences, and the literature contains rare reports of injuries and fatalities resulting from such explosions. We report the 2003 Fourth of July commercial fireworks explosion on Lovers Key in southwest Florida that resulted in five fatalities. Events occurring during the investigation of the scene of this explosion illustrate the unique considerations and hazards for medicolegal death investigators, law enforcement and other investigative agencies. Additionally, this case demonstrates unusual aspects of the postmortem examinations performed on victims of fireworks-related incidents.

  4. Quantum election scheme based on anonymous quantum key distribution

    NASA Astrophysics Data System (ADS)

    Zhou, Rui-Rui; Yang, Li

    2012-08-01

    An unconditionally secure authority-certified anonymous quantum key distribution scheme using conjugate coding is presented, based on which we construct a quantum election scheme without the help of an entanglement state. We show that this election scheme ensures the completeness, soundness, privacy, eligibility, unreusability, fairness, and verifiability of a large-scale election in which the administrator and counter are semi-honest. This election scheme can work even if there exist loss and errors in quantum channels. In addition, any irregularity in this scheme is sensible.

  5. Key participants in codeveloped technology pose for group picture

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Following the presentation of the Universal Signal Conditioning Amplifier (USCA), a new piece of technology developed through a National Aeronautics and Space Administration (NASA) partnership with industry, to Kennedy Space Center (KSC) Director Roy Bridges, Jr., key participants in the partnership pose for a group portrait. They are (from left) Bill Larson, NASA; Dr. Pedro Medelius, INET; Roy Bridges, Jr., KSC Director; Ed Gladney and William Saputo, L-3 Communications; Pam Gillespi, representing Congressman Dave Weldon; and Frank Kinney, Technological Research and Development Authority. The USCA is a key component of the codeveloped Automated Data Acquisition System (ADAS) that measures temperature, pressure and vibration at KSC's launch pads. The breakthrough technology is expected to reduce sensor setup and configuration times from hours to seconds. KSC teamed up with Florida's Technological Research and Development Authority and manufacturer L-3 Communications to produce a system that would benefit the aerospace industry and other commercial markets.

  6. Practical issues in quantum-key-distribution postprocessing

    SciTech Connect

    Fung, C.-H. Fred; Chau, H. F.; Ma Xiongfeng

    2010-01-15

    Quantum key distribution (QKD) is a secure key generation method between two distant parties by wisely exploiting properties of quantum mechanics. In QKD, experimental measurement outcomes on quantum states are transformed by the two parties to a secret key. This transformation is composed of many logical steps (as guided by security proofs), which together will ultimately determine the length of the final secret key and its security. We detail the procedure for performing such classical postprocessing taking into account practical concerns (including the finite-size effect and authentication and encryption for classical communications). This procedure is directly applicable to realistic QKD experiments and thus serves as a recipe that specifies what postprocessing operations are needed and what the security level is for certain lengths of the keys. Our result is applicable to the BB84 protocol with a single or entangled photon source.

  7. Practical issues in quantum-key-distribution postprocessing

    NASA Astrophysics Data System (ADS)

    Fung, Chi-Hang Fred; Ma, Xiongfeng; Chau, H. F.

    2010-01-01

    Quantum key distribution (QKD) is a secure key generation method between two distant parties by wisely exploiting properties of quantum mechanics. In QKD, experimental measurement outcomes on quantum states are transformed by the two parties to a secret key. This transformation is composed of many logical steps (as guided by security proofs), which together will ultimately determine the length of the final secret key and its security. We detail the procedure for performing such classical postprocessing taking into account practical concerns (including the finite-size effect and authentication and encryption for classical communications). This procedure is directly applicable to realistic QKD experiments and thus serves as a recipe that specifies what postprocessing operations are needed and what the security level is for certain lengths of the keys. Our result is applicable to the BB84 protocol with a single or entangled photon source.

  8. Anthelmintic administration to small ruminants in emergency drought responses: assessing the impact in two locations of northern Kenya.

    PubMed

    Okell, Claire Natasha; Mariner, Jeffrey; Allport, Robert; Buono, Nicoletta; Mutembei, Henry M'Ikiugu; Rushton, Jonathan; Verheyen, Kristien

    2016-03-01

    Internal parasites are a significant determinant of the productivity of ruminant species in the tropics. Provision of anthelmintics has become a predominant part of animal health interventions in emergency drought responses, aiming to maintain the food conversion efficiency of livestock when pasture is scarce. This study aimed to assess the owner-perceived impact of anthelmintic provision on the health and productivity of small ruminants in the drought-prone counties of Isiolo and Marsabit, northern Kenya. Participatory approaches were used to retrospectively measure differences in key indicators of livestock output before and after anthelmintic administration. Results showed that there was no perceived impact of anthelmintic administration during droughts on small ruminant health and productivity, but some benefit of anthelmintic administration during rainy season was perceived. The study also provided some evidence of potential differences in the epidemiology of internal parasites between the counties. These findings may be utilised to inform future livestock intervention programmes in drought-prone areas.

  9. Small private key MQPKS on an embedded microprocessor.

    PubMed

    Seo, Hwajeong; Kim, Jihyun; Choi, Jongseok; Park, Taehwan; Liu, Zhe; Kim, Howon

    2014-03-19

    Multivariate quadratic (MQ) cryptography requires the use of long public and private keys to ensure a sufficient security level, but this is not favorable to embedded systems, which have limited system resources. Recently, various approaches to MQ cryptography using reduced public keys have been studied. As a result of this, at CHES2011 (Cryptographic Hardware and Embedded Systems, 2011), a small public key MQ scheme, was proposed, and its feasible implementation on an embedded microprocessor was reported at CHES2012. However, the implementation of a small private key MQ scheme was not reported. For efficient implementation, random number generators can contribute to reduce the key size, but the cost of using a random number generator is much more complex than computing MQ on modern microprocessors. Therefore, no feasible results have been reported on embedded microprocessors. In this paper, we propose a feasible implementation on embedded microprocessors for a small private key MQ scheme using a pseudo-random number generator and hash function based on a block-cipher exploiting a hardware Advanced Encryption Standard (AES) accelerator. To speed up the performance, we apply various implementation methods, including parallel computation, on-the-fly computation, optimized logarithm representation, vinegar monomials and assembly programming. The proposed method reduces the private key size by about 99.9% and boosts signature generation and verification by 5.78% and 12.19% than previous results in CHES2012.

  10. Small Private Key PKS on an Embedded Microprocessor

    PubMed Central

    Seo, Hwajeong; Kim, Jihyun; Choi, Jongseok; Park, Taehwan; Liu, Zhe; Kim, Howon

    2014-01-01

    Multivariate quadratic ( ) cryptography requires the use of long public and private keys to ensure a sufficient security level, but this is not favorable to embedded systems, which have limited system resources. Recently, various approaches to cryptography using reduced public keys have been studied. As a result of this, at CHES2011 (Cryptographic Hardware and Embedded Systems, 2011), a small public key scheme, was proposed, and its feasible implementation on an embedded microprocessor was reported at CHES2012. However, the implementation of a small private key scheme was not reported. For efficient implementation, random number generators can contribute to reduce the key size, but the cost of using a random number generator is much more complex than computing on modern microprocessors. Therefore, no feasible results have been reported on embedded microprocessors. In this paper, we propose a feasible implementation on embedded microprocessors for a small private key scheme using a pseudo-random number generator and hash function based on a block-cipher exploiting a hardware Advanced Encryption Standard (AES) accelerator. To speed up the performance, we apply various implementation methods, including parallel computation, on-the-fly computation, optimized logarithm representation, vinegar monomials and assembly programming. The proposed method reduces the private key size by about 99.9% and boosts signature generation and verification by 5.78% and 12.19% than previous results in CHES2012. PMID:24651722

  11. Youth and administrator perspectives on transition in Kentucky's state agency schools.

    PubMed

    Marshall, Amy; Powell, Norman; Pierce, Doris; Nolan, Ronnie; Fehringer, Elaine

    2012-01-01

    Students, a large percentage with disabilities, are at high risk for poor post-secondary outcomes in state agency education programs. This mixed-methods study describes the understandings of student transitions in state agency education programs from the perspectives of youth and administrators. Results indicated that: transition is more narrowly defined within alternative education programs; key strengths of transition practice are present in nontraditional schools; and the coordination barriers within this fluid inter-agency transition system are most apparent in students' frequent inter-setting transitions between nontraditional and home schools.

  12. Free Energy Landscape - Settlements of Key Residues.

    NASA Astrophysics Data System (ADS)

    Aroutiounian, Svetlana

    2007-03-01

    FEL perspective in studies of protein folding transitions reflects notion that since there are ˜10^N conformations to scan in search of lowest free energy state, random search is beyond biological timescale. Protein folding must follow certain fel pathways and folding kinetics of evolutionary selected proteins dominates kinetic traps. Good model for functional robustness of natural proteins - coarse-grained model protein is not very accurate but affords bringing simulations closer to biological realm; Go-like potential secures the fel funnel shape; biochemical contacts signify the funnel bottleneck. Boltzmann-weighted ensemble of protein conformations and histogram method are used to obtain from MC sampling of protein conformational space the approximate probability distribution. The fel is F(rmsd) = -1/βLn[Hist(rmsd)], β=kBT and rmsd is root-mean-square-deviation from native conformation. The sperm whale myoglobin has rich dynamic behavior, is small and large - on computational scale, has a symmetry in architecture and unusual sextet of residue pairs. Main idea: there is a mathematical relation between protein fel and a key residues set providing stability to folding transition. Is the set evolutionary conserved also for functional reasons? Hypothesis: primary sequence determines the key residues positions conserved as stabilizers and the fel is the battlefield for the folding stability. Preliminary results: primary sequence - not the architecture, is the rule settler, indeed.

  13. Fully device-independent quantum key distribution.

    PubMed

    Vazirani, Umesh; Vidick, Thomas

    2014-10-01

    Quantum cryptography promises levels of security that are impossible to replicate in a classical world. Can this security be guaranteed even when the quantum devices on which the protocol relies are untrusted? This central question dates back to the early 1990s when the challenge of achieving device-independent quantum key distribution was first formulated. We answer this challenge by rigorously proving the device-independent security of a slight variant of Ekert's original entanglement-based protocol against the most general (coherent) attacks. The resulting protocol is robust: While assuming only that the devices can be modeled by the laws of quantum mechanics and are spatially isolated from each other and from any adversary's laboratory, it achieves a linear key rate and tolerates a constant noise rate in the devices. In particular, the devices may have quantum memory and share arbitrary quantum correlations with the eavesdropper. The proof of security is based on a new quantitative understanding of the monogamous nature of quantum correlations in the context of a multiparty protocol.

  14. Fully device-independent quantum key distribution.

    PubMed

    Vazirani, Umesh; Vidick, Thomas

    2014-10-01

    Quantum cryptography promises levels of security that are impossible to replicate in a classical world. Can this security be guaranteed even when the quantum devices on which the protocol relies are untrusted? This central question dates back to the early 1990s when the challenge of achieving device-independent quantum key distribution was first formulated. We answer this challenge by rigorously proving the device-independent security of a slight variant of Ekert's original entanglement-based protocol against the most general (coherent) attacks. The resulting protocol is robust: While assuming only that the devices can be modeled by the laws of quantum mechanics and are spatially isolated from each other and from any adversary's laboratory, it achieves a linear key rate and tolerates a constant noise rate in the devices. In particular, the devices may have quantum memory and share arbitrary quantum correlations with the eavesdropper. The proof of security is based on a new quantitative understanding of the monogamous nature of quantum correlations in the context of a multiparty protocol. PMID:25325625

  15. SARS: Key factors in crisis management.

    PubMed

    Tseng, Hsin-Chao; Chen, Thai-Form; Chou, Shieu-Ming

    2005-03-01

    This study was conducted at a single hospital selected in Taipei during the SARS (Severe Acute Respiratory Syndrome) outbreak from March to July, 2003 in Taiwan. During this period of time, 104 SARS patients were admitted to the hospital. There were no negative reports related to the selected hospital despite its being located right in the center of an area struck by the epidemic. The purpose of this study was to identify the key factors enabling the hospital to survive SARS unscathed. Data were collected from in-depth interviews with the nursing directors and nursing managers of the SARS units, along with a review of relevant hospital documents. The five key elements identified as survival factors during this SARS crisis are as follows: 1. good control of timing for crisis management, 2. careful decision-making, 3. thorough implementation, 4. effective communication, and 5. trust between management and employees. The results of this study reconfirmed the selected hospital as a model for good crisis management during the SARS epidemic.

  16. [Improvement of protection given by vaccination for socially underprivileged groups on the basis of "key persons approach" -- results of an intervention based on cultural and language aspects for children of immigrants in Altlander Viertel provided by the Health Department of Stade].

    PubMed

    Pallasch, G; Salman, R; Hartwig, C

    2005-01-01

    In January 2002, a vaccination campaign against measles, mumps and rubella was carried out in the Altlander Viertel, a district in Stade, Germany. The campaign was directed towards children of immigrants, a group often at a disadvantage in terms of health. This campaign was organised and carried out by the public health department in Stade for the first time in September 2002. During regular health screenings when children were enrolled for school it was found that they children were poorly protected by vaccination against measles, mumps and rubella. Since several attempts to improve the situation, for example by organising information events, had not been successful, it was decided to develop special measures for this particular group in order to improve their health. Together with the Ethno-Medical Centre in Hanover the concept of a vaccination campaign considering the special situation of immigrants was developed. The core measures were to find, train and use key persons within the groups of immigrants are living in the Altlander Viertel in Stade. These key persons helped to inform and motivate the immigrants to go to the vacciantion stations set up in the district. In this way it was possible to carry out a successful intervention (vaccination campaign). PMID:15672304

  17. 48 CFR 30.607 - Subcontract administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Administration 30.607 Subcontract administration. When a negotiated CAS price adjustment or a determination of noncompliance is required at...

  18. 48 CFR 30.607 - Subcontract administration.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Administration 30.607 Subcontract administration. When a negotiated CAS price adjustment or a determination of noncompliance is required at...

  19. 48 CFR 30.607 - Subcontract administration.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Administration 30.607 Subcontract administration. When a negotiated CAS price adjustment or a determination of noncompliance is required at...

  20. Finite-key security analysis of quantum key distribution with imperfect light sources

    NASA Astrophysics Data System (ADS)

    Mizutani, Akihiro; Curty, Marcos; Lim, Charles Ci Wen; Imoto, Nobuyuki; Tamaki, Kiyoshi

    2015-09-01

    In recent years, the gap between theory and practice in quantum key distribution (QKD) has been significantly narrowed, particularly for QKD systems with arbitrarily flawed optical receivers. The status for QKD systems with imperfect light sources is however less satisfactory, in the sense that the resulting secure key rates are often overly dependent on the quality of state preparation. This is especially the case when the channel loss is high. Very recently, to overcome this limitation, Tamaki et al proposed a QKD protocol based on the so-called ‘rejected data analysis’, and showed that its security—in the limit of infinitely long keys—is almost independent of any encoding flaw in the qubit space, being this protocol compatible with the decoy state method. Here, as a step towards practical QKD, we show that a similar conclusion is reached in the finite-key regime, even when the intensity of the light source is unstable. More concretely, we derive security bounds for a wide class of realistic light sources and show that the bounds are also efficient in the presence of high channel loss. Our results strongly suggest the feasibility of long distance provably secure communication with imperfect light sources.

  1. Key Stakeholders’ Perceptions of Motivators for Research Participation among Individuals who are Incarcerated

    PubMed Central

    Hanson, Bridget L.; Faulkner, Sherilyn A.; Brems, Christiane; Corey, Staci L.; Eldridge, Gloria D.; Johnson, Mark E.

    2015-01-01

    Understanding motivations of research participants is crucial for developing ethical research protocols, especially for research with vulnerable populations. Through interviews with 92 IRB members, prison administrators, research ethicists, and researchers, we explored key stakeholders’ perceptions of what motivates incarcerated individuals to participate in research. Primary motivators identified were a desire to contribute to society, gaining knowledge and healthcare, acquiring incentives, and obtaining social support. The potential for undue influence or coercion were also identified as motivators. These results highlight the need for careful analysis of what motivates incarcerated individuals to participate in research as part of developing or reviewing ethically permissible and responsible research protocols. Future research should expand this line of inquiry to directly include perspectives of incarcerated individuals. PMID:26283681

  2. Attitudes, Administrative Styles, and Outcomes.

    ERIC Educational Resources Information Center

    Laughlin, J. Stanley

    1984-01-01

    The literature on administrative style is reviewed. Attention is directed to four basic concepts of administrative style: (1) the structured, classical, traditional model; (2) the participatory or employee-involved operation; (3) a more behavioral scientific style; and (4) the situational or environmental style. These ideas are more fully…

  3. Network Systems Administration Needs Assessment.

    ERIC Educational Resources Information Center

    Lexington Community Coll., KY. Office of Institutional Research.

    In spring 1996, Lexington Community College (LCC) in Kentucky, conducted a survey to gather information on employment trends and educational needs in the field of network systems administration (NSA). NSA duties involve the installation and administration of network operating systems, applications software, and networking infrastructure;…

  4. Coaches Guide to Sport Administration.

    ERIC Educational Resources Information Center

    Leith, Larry M.

    This guide for athletic coaches offers a practical approach to the administrative functions of organizing, planning, leading, and controlling. Included are chapters on coaching administration, fund raising, organizing competitions, and designing effective budgets and controls. The guide addresses the following topics: (1) the categories of…

  5. Toward an Applied Administrative Science.

    ERIC Educational Resources Information Center

    Dunbar, Roger L. M.

    1983-01-01

    A study of 65 articles from the 1981 volumes of "Administrative Science Quarterly" and "Harvard Business Review," using smallest space analysis, found that the few studies adopting subjective (instead of objective) approaches to analyzing organizational change were most likely to provide a basis for an applied administrative science. (Author/RW)

  6. How to Control Administrative Cost.

    ERIC Educational Resources Information Center

    Halfond, Jay A.

    1991-01-01

    Growth in college administration has increased costs and bureaucracy. Rather than wait for fiscal crisis or consumer revolt, academic leaders, including faculty and administrators, should initiate change by simplifying activities and procedures and rewarding consolidation. The challenge is to use resources more effectively and efficiently in a…

  7. Administrative Approaches to Educational Productivity.

    ERIC Educational Resources Information Center

    Koski, William S.; Levin, Henry M.

    1998-01-01

    Presents an institutional framework for raising higher education productivity through administrative and organizational devices: first, by examining two theories for explaining rising higher education costs and their different policy consequences, and then by presenting an administrative process for improving productivity that focuses on…

  8. Child Nutrition Programs. Administrative Manual.

    ERIC Educational Resources Information Center

    Utah State Office of Education, Salt Lake City.

    Recognizing the importance of efficient and effective program administration for the success of Utah's Child Nutrition Programs, the State Office of Education developed a manual to assist local program administrators in using the U.S. Department of Agriculture's (USDA's) programs. This document contains Part 1 of the manual's four interrelated…

  9. International Developments in Educational Administration.

    ERIC Educational Resources Information Center

    Stone, Franklin D.

    Review of the history and characteristics of international organizations in educational administration suggests that the time may be right for a worldwide organization. Five international organizations have formed since 1959, when the University Council for Educational Administration linked U.S. and Canadian educators. A chronological chart…

  10. Legal Administrative Systems. Curriculum Guide.

    ERIC Educational Resources Information Center

    Patton, Jan

    This curriculum guide provides materials for teachers to use in developing a course in legal administrative systems. Following an introductory section that lists the common essential elements of the course, the guide contains six sections that cover the following course topics: (1) introduction to legal administrative systems; (2) word processing;…

  11. Medical Administrative Systems. Curriculum Guide.

    ERIC Educational Resources Information Center

    Patton, Jan

    This curriculum guide provides materials for teachers to use in developing a course in medical administrative systems. Following an introductory section that lists the common essential elements of the course, the guide contains seven sections that cover the following course topics: (1) introduction to medical administrative systems; (2) word…

  12. Faculty Perspectives on Administrator Effectiveness.

    ERIC Educational Resources Information Center

    Bess, James L.

    The sources of faculty perspectives on the personal effectiveness of administrators are analyzed. It is proposed that faculty will be predisposed to see administrators in different lights, depending on structural elements in decision making and the orientation of the faculty members. Attention is directed to Talcott Parson's theory for classifying…

  13. Canadian and Comparative Educational Administration.

    ERIC Educational Resources Information Center

    Farquhar, Robin H., Ed.; Housego, Ian E., Ed.

    Most of the articles in this book evolved from papers presented during the Fourth Quadrennial International Intervisitation Program in Educational Administration held in Canada in 1978. Its purposes were to inform educational leaders from around the world about educational administration, organization, and policy in Canada and to provide a forum…

  14. In Praise of Fewer Administrators.

    ERIC Educational Resources Information Center

    Nichols, Donald D.; Stuart, William H.

    In response to increasing financial pressures, Oakland Community College instituted a policy in the 1970s to reduce the number of college administrators as a means of saving staff costs. While student enrollments increased from 11,700 in 1970 to 24,000 in 1980, the number of administrators fell from 84 to 32. This reduction was realized through…

  15. Writing Program Administration as Conversation.

    ERIC Educational Resources Information Center

    Recchio, Tom

    1998-01-01

    Considers relations between the official pedagogy of the writing program that the author administers and his administrative practices, to come to terms with the hidden curriculum of his situation. Argues for a shift from thinking about administration as masterful organization and implementation to conceiving of it as relational and receptive, a…

  16. Principals' Values in School Administration

    ERIC Educational Resources Information Center

    Aslanargun, Engin

    2012-01-01

    School administration is value driven area depending on the emotions, cultures, and human values as well as technique and structure. Over the long years, educational administration throughout the world have experienced the influence of logical positivism that is based on rational techniques more than philosophical consideration, ignored values and…

  17. Communication Skills for Educational Administrators.

    ERIC Educational Resources Information Center

    Rowicki, Mark A.

    This paper reviews and discusses the literature related to improving effective communication in educational settings. It compiles possible solutions to ineffective communications. To promote effective communication, administrators need to solicit opinions and be willing to listen to them. Most administrators tend to give direction instead of…

  18. Public Finance Administration. Second Edition.

    ERIC Educational Resources Information Center

    Reed, B. J.; Swain, John W.

    This book is intended for the nonexpert in finance who has a public administration background. It opens with a broad introduction to public finance administration and how this job is related to public budgeting, the practice of public-sector accounting, and the economic concepts of money and value. Issues surrounding public revenue, its sources,…

  19. The Magic of Library Administration.

    ERIC Educational Resources Information Center

    Holley, Edward G.

    We are better prepared today to deal with the problems in library administration, because we not only have the basic work of management theorists, but also staffs who are better educated and more interested in participation. During the last 25 years, there have been two strands in library administration. The older, human relations approach allowed…

  20. Managing Time: An Administrator's Guide.

    ERIC Educational Resources Information Center

    Neal, Richard G.

    Following a brief discussion of the concept of time as a resource and a clarification of that resource's importance, the author analyzes 20 ways administrators waste time and 40 ways administrators can save time. None of the techniques suggested require special forms or training. The time wasters considered fall into the areas of personal…