Sample records for administration subject category

  1. NASA Scope and Subject Category Guide

    NASA Technical Reports Server (NTRS)

    2011-01-01

    This guide provides a simple, effective tool to assist aerospace information analysts and database builders in the high-level subject classification of technical materials. Each of the 76 subject categories comprising the classification scheme is presented with a description of category scope, a listing of subtopics, cross references, and an indication of particular areas of NASA interest. The guide also includes an index of nearly 3,000 specific research topics cross referenced to the subject categories. The portable document format (PDF) version of the guide contains links in the index from each input subject to its corresponding categories. In addition to subject classification, the guide can serve as an aid to searching databases that use the classification scheme, and is also an excellent selection guide for those involved in the acquisition of aerospace literature. The CD-ROM contains both HTML and PDF versions.

  2. Training and subjective workload in a category search task

    NASA Technical Reports Server (NTRS)

    Vidulich, Michael A.; Pandit, Parimal

    1986-01-01

    This study examined automaticity as a means by which training influences mental workload. Two groups were trained in a category search task. One group received a training paradigm designed to promote the development of automaticity; the other group received a training paradigm designed to prohibit it. Resultant performance data showed the expected improvement as a result of the development of automaticity. Subjective workload assessments mirrored the performance results in most respects. The results supported the position that subjective mental workload assessments may be sensitive to the effect of training when it produces a lower level of cognitive load.

  3. Discrimination and subjective well-being: protective influences of membership in a discriminated category.

    PubMed

    Hnilica, Karel

    2011-03-01

    Research reveals that discrimination has harmful effects on health and quality of life. Among the most frequent types of discrimination pertains gender and age discrimination. Research results show that discriminatory behaviours based on gender afflict predominantly women; age discrimination afflicts mainly older adults. At the same time, it has been found that members of these traditionally discriminated categories often use strategies that mitigate the effects of discrimination. Discrimination will have detrimental effects on subjective well-being. But its effects will be most harmful for persons who are not members of the traditionally discriminated categories. These hypotheses were tested on data from three waves of the European Social Survey that the Czech Republic also participated in. Data were analyzed in a series of multilevel random coefficients regression analyses with respondents nested within states and states nested within years of study. Both perceived gender discrimination and perceived age discrimination have negative effects on subjective well-being. However, gender discrimination had more harmful effects on the subjective well-being of men than women and age discrimination had the most harmful effects on the subjective well-being of people in their middle ages, not the elderly ones. Discrimination does not need to have most harmful effects on the quality of life of members of the categories that are discriminated against most often.

  4. Sleeping Pill Administration Time and Patient Subjective Satisfaction

    PubMed Central

    Chung, Seockhoon; Youn, Soyoung; Yi, Kikyoung; Park, Boram; Lee, Suyeon

    2016-01-01

    Study Objectives: Taking hypnotic agents 30 min before bedtime is the usual suggested administration time, but some patients report dissatisfaction with their sleeping pills. We investigated whether the timing of sleeping pill administration influences patient subjective satisfaction with these drugs. Methods: One hundred twelve patients with primary insomnia currently taking benzodiazepine or nonbenzodiazepine gamma-aminobutyric acid (GABA) agonists as sleeping pills were selected. The time of administration for their sleeping pills, bedtime, sleep onset time, and wake up time were obtained from their medical records. Subjects were also categorized into satisfied or dissatisfied groups. Results: Hypnotic agents administration time (p < 0.001) and bedtime (p < 0.001), but not sleep onset or wake up time, occurred later in the night in the satisfied group. The durations from administration of pills to sleep onset (33.6 ± 20.7 min) and to wake up time (7.2 ± 1.2 h) were significantly shorter in the satisfied group when compared to the dissatisfied group (135.9 ± 73.4 min and 9.3 ± 1.5 h for time to sleep onset and wake up, respectively). Logistic regression analysis revealed that patient subjective satisfaction with hypnotic agents could be predicted by a short duration from administration of pills to sleep onset (odds ratio = 0.01; 95% confidence interval [0.001–0.09]) and a short duration from administration of pills to wake up time (0.53; [0.31–0.89], F = 49.9, p < 0.001). Conclusions: Taking sleeping pills at a later time and a shorter interval between pill administration and wake up time may increase patient subjective satisfaction with hypnotic agents. We propose that physicians advise patients to take sleeping pills approximately 7 h before their usual getting-out-of-bed time instead of the current standard of 30 min before bedtime. Citation: Chung S, Youn S, Yi K, Park B, Lee S. Sleeping pill administration time and patient subjective satisfaction. J

  5. How Search for Meaning Interacts with Complex Categories of Meaning in Life and Subjective Well-Being?

    PubMed

    Damásio, Bruno Figueiredo; Koller, Sílvia Helena

    2015-03-03

    This study sought to assess how the search for meaning interacts with crisis of meaning and with different categories of meaning in life (meaningfulness, crisis of meaning, existential indifference, and existential conflict). Furthermore, the moderation role of search for meaning between the relation of categories of meaning and subjective well-being (SWB) was also evaluated. Participants included 3,034 subjects (63.9% women) ranging in age from 18 to 91 (M = 33.90; SD = 15.01) years old from 22 Brazilian states. Zero-order correlations and a factorial MANOVA were implemented. Positive low correlations were found for search for meaning and crisis of meaning (r = .258; p < .001). Search for meaning presented a small-effect size moderation effect on the relation of the different categories of meaning with subjective happiness, F(6, 3008) = 2.698, p < .05; η2 = .004, but not for satisfaction with life, F(6, 3008) = .935, p = .47; η2 = .002. The differences on the levels of subjective happiness of those inserted in existential indifferent and conflicting categories differ depending on the levels of search for meaning. Further directions for future studies are proposed.

  6. Sleeping Pill Administration Time and Patient Subjective Satisfaction.

    PubMed

    Chung, Seockhoon; Youn, Soyoung; Yi, Kikyoung; Park, Boram; Lee, Suyeon

    2016-01-01

    Taking hypnotic agents 30 min before bedtime is the usual suggested administration time, but some patients report dissatisfaction with their sleeping pills. We investigated whether the timing of sleeping pill administration influences patient subjective satisfaction with these drugs. One hundred twelve patients with primary insomnia currently taking benzodiazepine or nonbenzodiazepine gamma-aminobutyric acid (GABA) agonists as sleeping pills were selected. The time of administration for their sleeping pills, bedtime, sleep onset time, and wake up time were obtained from their medical records. Subjects were also categorized into satisfied or dissatisfied groups. Hypnotic agents administration time (p < 0.001) and bedtime (p < 0.001), but not sleep onset or wake up time, occurred later in the night in the satisfied group. The durations from administration of pills to sleep onset (33.6 ± 20.7 min) and to wake up time (7.2 ± 1.2 h) were significantly shorter in the satisfied group when compared to the dissatisfied group (135.9 ± 73.4 min and 9.3 ± 1.5 h for time to sleep onset and wake up, respectively). Logistic regression analysis revealed that patient subjective satisfaction with hypnotic agents could be predicted by a short duration from administration of pills to sleep onset (odds ratio = 0.01; 95% confidence interval [0.001-0.09]) and a short duration from administration of pills to wake up time (0.53; [0.31-0.89], F = 49.9, p < 0.001). Taking sleeping pills at a later time and a shorter interval between pill administration and wake up time may increase patient subjective satisfaction with hypnotic agents. We propose that physicians advise patients to take sleeping pills approximately 7 h before their usual getting-out-of-bed time instead of the current standard of 30 min before bedtime. © 2016 American Academy of Sleep Medicine.

  7. Dissociating hippocampal and basal ganglia contributions to category learning using stimulus novelty and subjective judgments

    PubMed Central

    Seger, Carol A.; Dennison, Christina S.; Lopez-Paniagua, Dan; Peterson, Erik J.; Roark, Aubrey A.

    2011-01-01

    We identified factors leading to hippocampal and basal ganglia recruitment during categorization learning. Subjects alternated between blocks of a standard trial and error category learning task and a subjective judgment task. In the subjective judgments task subjects categorized the stimulus and then instead of receiving feedback they indicated the basis of their response using 4 options: Remember: Conscious episodic memory of previous trials. Know-Automatic: Automatic, rapid response accompanied by conscious awareness of category membership. Know-Intuition: A “gut feeling” without fully conscious knowledge of category membership. Guess: Guessing. In addition, new stimuli were introduced throughout the experiment to examine effects of novelty. Categorization overall recruited both the basal ganglia and posterior hippocampus. However, basal ganglia activity was found during Know judgments (both Automatic and Intuition), whereas posterior hippocampus activity was found during Remember judgments. Granger causality mapping indicated interactions between the basal ganglia and hippocampus, with the putamen exerting directed influence on the posterior hippocampus, which in turn exerted directed influence on the posterior caudate nucleus. We also found a region of anterior hippocampus that showed decreased activity relative to baseline during categorization overall, and showed a strong novelty effect. Our results indicate that subjective measures may be effective in dissociating basal ganglia from hippocampal dependent learning, and that the basal ganglia are involved in both conscious and unconscious learning. They also indicate a dissociation within the hippocampus, in which the anterior regions are sensitive to novelty, and the posterior regions are involved in memory based categorization learning. PMID:21255655

  8. Mental representation of normal subjects about the sources of knowledge in different semantic categories and unique entities.

    PubMed

    Gainotti, Guido; Ciaraffa, Francesca; Silveri, Maria Caterina; Marra, Camillo

    2009-11-01

    According to the "sensory-motor model of semantic knowledge," different categories of knowledge differ for the weight that different "sources of knowledge" have in their representation. Our study aimed to evaluate this model, checking if subjective evaluations given by normal subjects confirm the different weight that various sources of knowledge have in the representation of different biological and artifact categories and of unique entities, such as famous people or monuments. Results showed that the visual properties are considered as the main source of knowledge for all the living and nonliving categories (as well as for unique entities), but that the clustering of these "sources of knowledge" is different for biological and artifacts categories. Visual data are, indeed, mainly associated with other perceptual (auditory, olfactory, gustatory, and tactual) attributes in the mental representation of living beings and unique entities, whereas they are associated with action-related properties and tactile information in the case of artifacts.

  9. 22 CFR 120.42 - Subject to the Export Administration Regulations (EAR).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Subject to the Export Administration Regulations (EAR). 120.42 Section 120.42 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.42 Subject to the Export Administration Regulations (EAR). Items...

  10. 31 CFR 205.18 - Are administrative costs subject to this part?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... or other system under an approved cost allocation plan, the State will draw down funds to meet cash... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Are administrative costs subject to... Treasury-State Agreement § 205.18 Are administrative costs subject to this part? (a) A State and FMS may...

  11. Laboratory-based testing to evaluate abuse-deterrent formulations and satisfy the Food and Drug Administration's recommendation for Category 1 Testing.

    PubMed

    Altomare, Christopher; Kinzler, Eric R; Buchhalter, August R; Cone, Edward J; Costantino, Anthony

    The US Food and Drug Administration (FDA) considers the development of abuse-deterrent formulations of solid oral dosage forms a public health priority and has outlined a series of premarket studies that should be performed prior to submitting an application to the Agency. Category 1 studies are performed to characterize whether the abuse-deterrent properties of a new formulation can be easily defeated. Study protocols are designed to evaluate common abuse patterns of prescription medications as well as more advanced methods that have been reported on drug abuse websites and forums. Because FDA believes Category 1 testing should fully characterize the abuse-deterrent characteristics of an investigational formulation, Category 1 testing is time consuming and requires specialized laboratory resources as well as advanced knowledge of prescription medication abuse. Recent Advisory Committee meetings at FDA have shown that Category 1 tests play a critical role in FDA's evaluation of an investigational formulation. In this article, we will provide a general overview of the methods of manipulation and routes of administration commonly utilized by prescription drug abusers, how those methods and routes are evaluated in a laboratory setting, and discuss data intake, analysis, and reporting to satisfy FDA's Category 1 testing requirements.

  12. Culture, category salience, and inductive reasoning.

    PubMed

    Choi, I; Nisbett, R E; Smith, E E

    1997-12-01

    The role of category salience in category-based induction was demonstrated in two ways: (i) temporarily increasing category salience facilitated category-based induction, and (ii) this effect was moderated by cultural differences that we predicted would be related to chronic category salience. Subjects for whom categories were presumed to be more accessible (Americans) were not as much influenced by manipulations to increase category salience as subjects who were presumed to have lower chronic accessibility of categories (Koreans). However, as anticipated, this pattern was reversed for inferences about behavioral properties of social categories. Due to the 'interdependent' nature of their culture, Koreans presumably have relatively higher chronic accessibility for social categories than do relatively 'independent' Americans, and hence were not influenced as much by increasing category salience.

  13. 28 CFR 94.22 - Categories of expenses.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Categories of expenses. 94.22 Section 94.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Coverage § 94.22 Categories of expenses. The following...

  14. 28 CFR 94.22 - Categories of expenses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Categories of expenses. 94.22 Section 94.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Coverage § 94.22 Categories of expenses. The following...

  15. 28 CFR 94.22 - Categories of expenses.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Categories of expenses. 94.22 Section 94.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Coverage § 94.22 Categories of expenses. The following...

  16. 28 CFR 94.22 - Categories of expenses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Categories of expenses. 94.22 Section 94.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Coverage § 94.22 Categories of expenses. The following...

  17. 28 CFR 94.22 - Categories of expenses.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Categories of expenses. 94.22 Section 94.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Coverage § 94.22 Categories of expenses. The following...

  18. Safety pharmacology of acute MDMA administration in healthy subjects.

    PubMed

    Vizeli, Patrick; Liechti, Matthias E

    2017-05-01

    3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is being investigated in MDMA-assisted psychotherapy. The present study characterized the safety pharmacology of single-dose administrations of MDMA (75 or 125 mg) using data from nine double-blind, placebo-controlled, crossover studies performed in the same laboratory in a total of 166 healthy subjects. The duration of the subjective effects was 4.2 ± 1.3 h (range: 1.4-8.2 h). The 125 mg dose of MDMA produced greater 'good drug effect' ratings than 75 mg. MDMA produced moderate and transient 'bad drug effect' ratings, which were greater in women than in men. MDMA increased systolic blood pressure to >160 mmHg, heart rate >100 beats/min, and body temperature >38°C in 33%, 29% and 19% of the subjects, respectively. These proportions of subjects with hypertension (>160 mmHg), tachycardia, and body temperature >38°C were all significantly greater after 125 mg MDMA compared with the 75 mg dose. Acute and subacute adverse effects of MDMA as assessed by the List of Complaints were dose-dependent and more frequent in females. MDMA did not affect liver or kidney function at EOS 29 ± 22 days after use. No serious adverse events occurred. In conclusion, MDMA produced predominantly acute positive subjective drug effects. Bad subjective drug effects and other adverse effects were significantly more common in women. MDMA administration was overall safe in physically and psychiatrically healthy subjects and in a medical setting. However, the risks of MDMA are likely higher in patients with cardiovascular disease and remain to be investigated in patients with psychiatric disorders.

  19. Tolerability, usability and acceptability of dissolving microneedle patch administration in human subjects

    PubMed Central

    Arya, Jaya; Henry, Sebastien; Kalluri, Haripriya; McAllister, Devin V.; Pewin, Winston P.; Prausnitz, Mark R.

    2017-01-01

    To support translation of microneedle patches from pre-clinical development into clinical trials, this study examined the effect of microneedle patch application on local skin reactions, reliability of use and acceptability to patients. Placebo patches containing dissolving microneedles were administered to fifteen human participants. Microneedle patches were well tolerated in the skin with no pain or swelling and only mild erythema localized to the site of patch administration that resolved fully within seven days. Microneedle patches could be administered by hand without the need of an applicator and delivery efficiencies were similar for investigator-administration and self-administration. Microneedle patch administration was not considered painful and the large majority of subjects were somewhat or fully confident that they self-administered patches correctly. Microneedle patches were overwhelmingly preferred over conventional needle and syringe injection. Altogether, these results demonstrate that dissolving microneedle patches were well tolerated, easily usable and strongly accepted by human subjects, which will facilitate further clinical translation of this technology. PMID:28285193

  20. Category-based predictions: influence of uncertainty and feature associations.

    PubMed

    Ross, B H; Murphy, G L

    1996-05-01

    Four experiments examined how people make inductive inferences using categories. Subjects read stories in which 2 categories were mentioned as possible identities of an object. The less likely category was varied to determine if people were using it, as well as the most likely category, in making predictions about the object. Experiment 1 showed that even when categorization uncertainty was emphasized, subjects used only 1 category as the basis for their prediction. Experiments 2-4 examined whether people would use multiple categories for making predictions when the feature to be predicted was associated to the less likely category. Multiple categories were used in this case, but only in limited circumstances; furthermore, using multiple categories in 1 prediction did not cause subjects to use them for subsequent predictions. The results increase the understanding of how categories are used in inductive inference.

  1. The Merging Categories: Appropriate Education or Administrative Convenience?

    ERIC Educational Resources Information Center

    Phipps, Patricia M.

    1982-01-01

    The trend to include mildly mentally retarded, emotionally disturbed (behavior disordered), and learning disabled children in the same generic category and in the same school programs is increasing. The author believes that the noncategorical trend in special education can endanger the appropriate education of many children. (Author)

  2. Class categories and the subjective dimension of class: the case of Denmark.

    PubMed

    Harrits, Gitte Sommer; Pedersen, Helene Helboe

    2018-03-01

    Class relations have been proven to affect various aspects of social life, even in modern individualized societies. However, following claims on individualization and the so-called 'death of class' thesis, studying the subjective dimension of class - that is, the way individuals perceive of class relations and their own position within them - has gone out of style. We argue that even in equalized societies, subjective class perceptions may still influence attitudes and behaviour as they evolve to fit modern class relations. To explore the existence as well as structure and content of perceived social classes, this article investigates how people describe society and social groups in focus group discussions. We find that groups in different positions in terms of education and economy all tend to apply hierarchical class categories to describe Danish society, which is normally seen as one of the most equal societies and political systems in the world. In addition, we find that economic resources serve as a baseline for the hierarchical ordering, often supplemented with notions of education, lifestyle and/or occupational profile. Even though people are somewhat uncomfortable with the notion of class, their descriptions of Danish society and classes are surprisingly similar within and across groups. We conclude that not only do class relations matter; people are also highly aware of the existing classes and able to position themselves and others according to their notion of classes. © London School of Economics and Political Science 2017.

  3. 1 CFR 5.9 - Categories of documents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Categories of documents. 5.9 Section 5.9 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.9 Categories of documents. Each document published in the Federal Register shall be placed under one of the...

  4. 1 CFR 5.9 - Categories of documents.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Categories of documents. 5.9 Section 5.9 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.9 Categories of documents. Each document published in the Federal Register shall be placed under one of the...

  5. 1 CFR 5.9 - Categories of documents.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Categories of documents. 5.9 Section 5.9 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.9 Categories of documents. Each document published in the Federal Register shall be placed under one of the...

  6. 1 CFR 5.9 - Categories of documents.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Categories of documents. 5.9 Section 5.9 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.9 Categories of documents. Each document published in the Federal Register shall be placed under one of the following...

  7. 1 CFR 5.9 - Categories of documents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Categories of documents. 5.9 Section 5.9 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.9 Categories of documents. Each document published in the Federal Register shall be placed under one of the following...

  8. Decreased oral bioavailability of loxoprofen at second administration in human subjects.

    PubMed

    Kim, I W; Choo, K S; Han, T G; Kim, K S; Chung, S J; Lee, M H; Shim, C K

    2000-01-01

    The objective of this study was to determine the extent of period effect on the pharmacokineitcs of loxoprofen during consecutive dosing. Loxipen and Loxonin tablets were administered to 16 healthy Korean male subjects at a single dose of 60 mg as loxoprofen sodium anhydrous in a 2 x 2 crossover investigation with a two-week wash-out phase. Concentrations of loxoprofen in plasma were measured by HPLC method for 6 h. The two formulations were found bioequivalent, but analysis of variance (ANOVA) indicated that there was a significant (p < 0.05) period effect in AUCinf (area under the plasma concentration-time curve from time zero to infinity) between the administrations. A 20% decrease in the AUC was seen at the second administration. This period effect on pharmacokinetics of loxoprofen may be relevant for the patients who need consecutive administration of the drug.

  9. Category inference as a function of correlational structure, category discriminability, and number of available cues.

    PubMed

    Lancaster, Matthew E; Shelhamer, Ryan; Homa, Donald

    2013-04-01

    Two experiments investigated category inference when categories were composed of correlated or uncorrelated dimensions and the categories overlapped minimally or moderately. When the categories minimally overlapped, the dimensions were strongly correlated with the category label. Following a classification learning phase, subsequent transfer required the selection of either a category label or a feature when one, two, or three features were missing. Experiments 1 and 2 differed primarily in the number of learning blocks prior to transfer. In each experiment, the inference of the category label or category feature was influenced by both dimensional and category correlations, as well as their interaction. The number of cues available at test impacted performance more when the dimensional correlations were zero and category overlap was high. However, a minimal number of cues were sufficient to produce high levels of inference when the dimensions were highly correlated; additional cues had a positive but reduced impact, even when overlap was high. Subjects were generally more accurate in inferring the category label than a category feature regardless of dimensional correlation, category overlap, or number of cues available at test. Whether the category label functioned as a special feature or not was critically dependent upon these embedded correlations, with feature inference driven more strongly by dimensional correlations.

  10. 9 CFR 329.1 - Article or livestock subject to administrative detention.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Article or livestock subject to administrative detention. 329.1 Section 329.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE... of the provisions of Title I of the Act, any other Federal law, or the laws of any State or Territory...

  11. Influence of Emotionally Charged Information on Category-Based Induction

    PubMed Central

    Zhu, Jennifer; Murphy, Gregory L.

    2013-01-01

    Categories help us make predictions, or inductions, about new objects. However, we cannot always be certain that a novel object belongs to the category we are using to make predictions. In such cases, people should use multiple categories to make inductions. Past research finds that people often use only the most likely category to make inductions, even if it is not certain. In two experiments, subjects read stories and answered questions about items whose categorization was uncertain. In Experiment 1, the less likely category was either emotionally neutral or dangerous (emotionally charged or likely to pose a threat). Subjects used multiple categories in induction when one of the categories was dangerous but not when they were all neutral. In Experiment 2, the most likely category was dangerous. Here, people used multiple categories, but there was also an effect of avoidance, in which people denied that dangerous categories were the most likely. The attention-grabbing power of dangerous categories may be balanced by a higher-level strategy to reject them. PMID:23372700

  12. Category-Specificity in Visual Object Recognition

    ERIC Educational Resources Information Center

    Gerlach, Christian

    2009-01-01

    Are all categories of objects recognized in the same manner visually? Evidence from neuropsychology suggests they are not: some brain damaged patients are more impaired in recognizing natural objects than artefacts whereas others show the opposite impairment. Category-effects have also been demonstrated in neurologically intact subjects, but the…

  13. 5 CFR 575.104 - Ineligible categories of employees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INCENTIVES Recruitment Incentives § 575.104 Ineligible categories of employees. An agency may not pay a recruitment incentive to an employee in— (a) A position to which an individual is appointed by the President... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Ineligible categories of employees. 575...

  14. The evaluation of sources of knowledge underlying different conceptual categories.

    PubMed

    Gainotti, Guido; Spinelli, Pietro; Scaricamazza, Eugenia; Marra, Camillo

    2013-01-01

    According to the "embodied cognition" theory and the "sensory-motor model of semantic knowledge": (a) concepts are represented in the brain in the same format in which they are constructed by the sensory-motor system and (b) various conceptual categories differ according to the weight of different kinds of information in their representation. In this study, we tried to check the second assumption by asking normal elderly subjects to subjectively evaluate the role of various perceptual, motor and language-mediated sources of knowledge in the construction of different semantic categories. Our first aim was to rate the influence of different sources of knowledge in the representation of animals, plant life and artifact categories, rather than in living and non-living beings, as many previous studies on this subject have done. We also tried to check the influence of age and stimulus modality on these evaluations of the "sources of knowledge" underlying different conceptual categories. The influence of age was checked by comparing results obtained in our group of elderly subjects with those obtained in a previous study, conducted with a similar methodology on a sample of young students. And the influence of stimulus modality was assessed by presenting the stimuli in the verbal modality to 50 subjects and in the pictorial modality to 50 other subjects. The distinction between "animals" and "plant life" in the "living" categories was confirmed by analyzing their prevalent sources of knowledge and by a cluster analysis, which allowed us to distinguish "plant life" items from animals. Furthermore, results of the study showed: (a) that our subjects considered the visual modality as the main source of knowledge for all categories taken into account; and (b) that in biological categories the next most important source of information was represented by other perceptual modalities, whereas in artifacts it was represented by the actions performed with them. Finally, age and

  15. 5 CFR 591.211 - What are the categories of consumer expenditures?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... groups (MEGs). These categories are food, shelter and utilities, clothing, transportation, household... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false What are the categories of consumer...-Of-Living Allowances § 591.211 What are the categories of consumer expenditures? OPM uses three...

  16. Perceptual Versus Semantic Information Processing in Semantic Category Decisions.

    ERIC Educational Resources Information Center

    Kamil, Michael L.; Hanson, Raymond H.

    This study examined the ability of junior high school students to use advance information when making semantic category decisions. The subjects, eight good readers and eight poor readers, identified paired words as "same" or "different" in category, with some words more highly associated with the category than others--in the "fruit" category, for…

  17. Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings.

    PubMed

    Sweeney, Mary M; Meredith, Steven E; Evatt, Daniel P; Griffiths, Roland R

    2017-03-01

    Combining alcohol and caffeine is associated with increased alcohol consumption, but no prospective experimental studies have examined whether added caffeine increases alcohol consumption. This study examined how caffeine alters alcohol self-administration and subjective reinforcing effects in healthy adults. Thirty-one participants completed six double-blind alcohol self-administration sessions: three sessions with alcohol only (e.g., beverage A) and three sessions with alcohol and caffeine (e.g., beverage B). Participants chose which beverage to consume on a subsequent session (e.g., beverage A or B). The effects of caffeine on overall beverage choice, number of self-administered drinks, subjective ratings (e.g., Biphasic Alcohol Effects Scale), and psychomotor performance were examined. A majority of participants (65%) chose to drink the alcohol beverage containing caffeine on their final self-administration session. Caffeine did not increase the number of self-administered drinks. Caffeine significantly increased stimulant effects, decreased sedative effects, and attenuated decreases in psychomotor performance attributable to alcohol. Relative to nonchoosers, caffeine choosers reported overall lower stimulant ratings and reported greater drinking behavior prior to the study. Although caffeine did not increase the number of self-administered drinks, most participants chose the alcohol beverage containing caffeine. Given the differences in subjective ratings and pre-existing differences in self-reported alcohol consumption for caffeine choosers and nonchoosers, these data suggest that decreased stimulant effects of alcohol and heavier self-reported drinking may predict subsequent choice of combined caffeine and alcohol beverages. These predictors may identify individuals who would benefit from efforts to reduce risk behaviors associated with combining alcohol and caffeine.

  18. 5 CFR 1303.50 - Fees to be charged-categories of requesters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Fees to be charged-categories of requesters. 1303.50 Section 1303.50 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES PUBLIC INFORMATION PROVISIONS OF THE ADMINISTRATIVE PROCEDURES ACT Charges for Search and...

  19. Effects of caffeine on alcohol reinforcement: Beverage choice, self-administration, and subjective ratings

    PubMed Central

    Sweeney, Mary M.; Meredith, Steven E.; Evatt, Daniel P.; Griffiths, Roland R.

    2017-01-01

    Rationale Combining alcohol and caffeine is associated with increased alcohol consumption, but no prospective experimental studies have examined whether added caffeine increases alcohol consumption. Objectives This study examined how caffeine alters alcohol self-administration and subjective reinforcing effects in healthy adults. Methods Thirty-one participants completed six double-blind alcohol self-administration sessions: three sessions with alcohol only (e.g., Beverage A) and three sessions with alcohol and caffeine (e.g., Beverage B). Participants chose which beverage to consume on a subsequent session (e.g., Beverage A or B). Effects of caffeine on overall beverage choice, number of self-administered drinks, subjective ratings (e.g., Biphasic Alcohol Effects Scale), and psychomotor performance were examined. Results A majority of participants (65%) chose to drink the alcohol beverage containing caffeine on their final self-administration session. Caffeine did not increase the number of self-administered drinks. Caffeine significantly increased stimulant effects, decreased sedative effects, and attenuated decreases in psychomotor performance attributable to alcohol. Relative to nonchoosers, caffeine choosers reported overall lower stimulant ratings, and reported greater drinking behavior prior to the study. Conclusions Although caffeine did not increase the number of self-administered drinks, most participants chose the alcohol beverage containing caffeine. Given the differences in subjective ratings and pre-existing differences in self-reported alcohol consumption for caffeine choosers and nonchoosers, these data suggest decreased stimulant effects of alcohol and heavier self-reported drinking may predict subsequent choice of combined caffeine and alcohol beverages. These predictors may identify individuals who would benefit from efforts to reduce risk behaviors associated with combining alcohol and caffeine. PMID:28108773

  20. Naltrexone Maintenance Decreases Cannabis Self-Administration and Subjective Effects in Daily Cannabis Smokers.

    PubMed

    Haney, Margaret; Ramesh, Divya; Glass, Andrew; Pavlicova, Martina; Bedi, Gillinder; Cooper, Ziva D

    2015-10-01

    Given that cannabis use is increasing in the United States, pharmacological treatment options to treat cannabis use disorder are needed. Opioid antagonists modulate cannabinoid effects and may offer a potential approach to reducing cannabis use. In this double-blind, placebo-controlled human laboratory study, we assessed the effects of naltrexone maintenance on the reinforcing, subjective, psychomotor, and cardiovascular effects of active and inactive cannabis. Nontreatment-seeking, daily cannabis smokers were randomized to receive naltrexone (50 mg: n=18 M and 5 F) or placebo (0 mg; n=26 M and 2 F) capsules for 16 days. Before, during, and after medication maintenance, participants completed 10 laboratory sessions over 4-6 weeks, assessing cannabis' behavioral and cardiovascular effects. Medication compliance was verified by observed capsule administration, plasma naltrexone, and urinary riboflavin. Relative to placebo, maintenance on naltrexone significantly reduced both active cannabis self-administration and its positive subjective effects ('good effect'). Participants in the placebo group had 7.6 times (95% CI: 1.1-51.8) the odds of self-administering active cannabis compared with the naltrexone group. This attenuation of reinforcing and positive subjective effects also influenced cannabis use in the natural ecology. Naltrexone had intrinsic effects: decreasing ratings of friendliness, food intake, and systolic blood pressure, and increasing spontaneous reports of stomach upset and headache, yet dropout rates were comparable between groups. In summary, we show for the first time that maintenance on naltrexone decreased cannabis self-administration and ratings of 'good effect' in nontreatment-seeking daily cannabis smokers. Clinical studies in patients motivated to reduce their cannabis use are warranted to evaluate naltrexone's efficacy as a treatment for cannabis use disorder.

  1. Legal and Administrative Feasibility of a Federal Junk Food and Sugar-Sweetened Beverage Tax to Improve Diet.

    PubMed

    Pomeranz, Jennifer L; Wilde, Parke; Huang, Yue; Micha, Renata; Mozaffarian, Dariush

    2018-02-01

    To evaluate legal and administrative feasibility of a federal "junk" food (including sugar-sweetened beverages [SSBs]) tax to improve diet. To assess food definitions and administration models, we systematically searched (1) PubMed (through May 15, 2017) for articles defining foods subject to taxes, and legal and legislative databases as well as online for (2) US federal, state, and tribal junk food tax bills and laws (January 1, 2012-February 28, 2017); SSB taxes (January 1, 2014-February 28, 2017); and international junk food tax laws (as of February 28, 2017); and (3) federal taxing mechanisms and administrative methods (as of February 28, 2017). Articles recommend taxing foods by product category, broad nutrient criteria, specific nutrients or calories, or a combination. US junk food tax bills (n = 6) and laws (n = 3), international junk food laws (n = 2), and US SSB taxes (n = 10) support taxing foods using category-based (n = 8), nutrient-based (n = 1), or combination (n = 12) approaches. Federal taxing mechanisms (particularly manufacturer excise taxes on alcohol) and administrative methods provide informative models. From legal and administrative perspectives, a federal junk food tax appears feasible based on product categories or combination category-plus-nutrient approaches, using a manufacturer excise tax, with additional support for sugar and graduated tax strategies.

  2. Naltrexone Maintenance Decreases Cannabis Self-Administration and Subjective Effects in Daily Cannabis Smokers

    PubMed Central

    Haney, Margaret; Ramesh, Divya; Glass, Andrew; Pavlicova, Martina; Bedi, Gillinder; Cooper, Ziva D

    2015-01-01

    Given that cannabis use is increasing in the United States, pharmacological treatment options to treat cannabis use disorder are needed. Opioid antagonists modulate cannabinoid effects and may offer a potential approach to reducing cannabis use. In this double-blind, placebo-controlled human laboratory study, we assessed the effects of naltrexone maintenance on the reinforcing, subjective, psychomotor, and cardiovascular effects of active and inactive cannabis. Nontreatment-seeking, daily cannabis smokers were randomized to receive naltrexone (50 mg: n=18 M and 5 F) or placebo (0 mg; n=26 M and 2 F) capsules for 16 days. Before, during, and after medication maintenance, participants completed 10 laboratory sessions over 4–6 weeks, assessing cannabis' behavioral and cardiovascular effects. Medication compliance was verified by observed capsule administration, plasma naltrexone, and urinary riboflavin. Relative to placebo, maintenance on naltrexone significantly reduced both active cannabis self-administration and its positive subjective effects (‘good effect'). Participants in the placebo group had 7.6 times (95% CI: 1.1–51.8) the odds of self-administering active cannabis compared with the naltrexone group. This attenuation of reinforcing and positive subjective effects also influenced cannabis use in the natural ecology. Naltrexone had intrinsic effects: decreasing ratings of friendliness, food intake, and systolic blood pressure, and increasing spontaneous reports of stomach upset and headache, yet dropout rates were comparable between groups. In summary, we show for the first time that maintenance on naltrexone decreased cannabis self-administration and ratings of ‘good effect' in nontreatment-seeking daily cannabis smokers. Clinical studies in patients motivated to reduce their cannabis use are warranted to evaluate naltrexone's efficacy as a treatment for cannabis use disorder. PMID:25881117

  3. Intraduodenal Administration of Intact Pea Protein Effectively Reduces Food Intake in Both Lean and Obese Male Subjects

    PubMed Central

    Geraedts, Maartje C. P.; Troost, Freddy J.; Munsters, Marjet J. M.; Stegen, Jos H. C. H.; de Ridder, Rogier J.; Conchillo, Jose M.; Kruimel, Joanna W.; Masclee, Ad A. M.; Saris, Wim H. M.

    2011-01-01

    Background Human duodenal mucosa secretes increased levels of satiety signals upon exposure to intact protein. However, after oral protein ingestion, gastric digestion leaves little intact proteins to enter the duodenum. This study investigated whether bypassing the stomach, through intraduodenal administration, affects hormone release and food-intake to a larger extent than orally administered protein in both lean and obese subjects. Methods Ten lean (BMI:23.0±0.7 kg/m2) and ten obese (BMI:33.4±1.4 kg/m2) healthy male subjects were included. All subjects randomly received either pea protein solutions (250 mg/kg bodyweight in 0.4 ml/kg bodyweight of water) or placebo (0.4 ml/kg bodyweight of water), either orally or intraduodenally via a naso-duodenal tube. Appetite-profile, plasma GLP-1, CCK, and PYY concentrations were determined over a 2 h period. After 2 h, subjects received an ad-libitum meal and food-intake was recorded. Results CCK levels were increased at 10(p<0.02) and 20(p<0.01) minutes after intraduodenal protein administration (IPA), in obese subjects, compared to lean subjects, but also compared to oral protein administration (OPA)(p<0.04). GLP-1 levels increased after IPA in obese subjects after 90(p<0.02) to 120(p<0.01) minutes, compared to OPA. Food-intake was reduced after IPA both in lean and obese subjects (-168.9±40 kcal (p<0.01) and −298.2±44 kcal (p<0.01), respectively), compared to placebo. Also, in obese subjects, food-intake was decreased after IPA (−132.6±42 kcal; p<0.01), compared to OPA. Conclusions Prevention of gastric proteolysis through bypassing the stomach effectively reduces food intake, and seems to affect obese subjects to a greater extent than lean subjects. Enteric coating of intact protein supplements may provide an effective dietary strategy in the prevention/treatment of obesity. PMID:21931864

  4. When More Is Less: Feedback Effects in Perceptual Category Learning

    ERIC Educational Resources Information Center

    Maddox, W. Todd; Love, Bradley C.; Glass, Brian D.; Filoteo, J. Vincent

    2008-01-01

    Rule-based and information-integration category learning were compared under minimal and full feedback conditions. Rule-based category structures are those for which the optimal rule is verbalizable. Information-integration category structures are those for which the optimal rule is not verbalizable. With minimal feedback subjects are told whether…

  5. When more is less: Feedback effects in perceptual category learning ☆

    PubMed Central

    Maddox, W. Todd; Love, Bradley C.; Glass, Brian D.; Filoteo, J. Vincent

    2008-01-01

    Rule-based and information-integration category learning were compared under minimal and full feedback conditions. Rule-based category structures are those for which the optimal rule is verbalizable. Information-integration category structures are those for which the optimal rule is not verbalizable. With minimal feedback subjects are told whether their response was correct or incorrect, but are not informed of the correct category assignment. With full feedback subjects are informed of the correctness of their response and are also informed of the correct category assignment. An examination of the distinct neural circuits that subserve rule-based and information-integration category learning leads to the counterintuitive prediction that full feedback should facilitate rule-based learning but should also hinder information-integration learning. This prediction was supported in the experiment reported below. The implications of these results for theories of learning are discussed. PMID:18455155

  6. 21 CFR 330.5 - Drug categories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Drug categories. 330.5 Section 330.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER (OTC) HUMAN DRUGS WHICH ARE GENERALLY RECOGNIZED AS SAFE AND EFFECTIVE AND NOT...

  7. 21 CFR 330.5 - Drug categories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Drug categories. 330.5 Section 330.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER (OTC) HUMAN DRUGS WHICH ARE GENERALLY RECOGNIZED AS SAFE AND EFFECTIVE AND NOT...

  8. 21 CFR 330.5 - Drug categories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Drug categories. 330.5 Section 330.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER (OTC) HUMAN DRUGS WHICH ARE GENERALLY RECOGNIZED AS SAFE AND EFFECTIVE AND NOT...

  9. 21 CFR 330.5 - Drug categories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Drug categories. 330.5 Section 330.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER (OTC) HUMAN DRUGS WHICH ARE GENERALLY RECOGNIZED AS SAFE AND EFFECTIVE AND NOT...

  10. 21 CFR 330.5 - Drug categories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Drug categories. 330.5 Section 330.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER (OTC) HUMAN DRUGS WHICH ARE GENERALLY RECOGNIZED AS SAFE AND EFFECTIVE AND NOT...

  11. Pathobiology and management of laboratory rodents administered CDC category A agents.

    PubMed

    He, Yongqun; Rush, Howard G; Liepman, Rachel S; Xiang, Zuoshuang; Colby, Lesley A

    2007-02-01

    The Centers for Disease Control and Prevention Category A infectious agents include Bacillus anthracis (anthrax), Clostridium botulinum toxin (botulism), Yersinia pestis (plague), variola major virus (smallpox), Francisella tularensis (tularemia), and the filoviruses and arenaviruses that induce viral hemorrhagic fevers. These agents are regarded as having the greatest potential for adverse impact on public health and therefore are a focus of renewed attention in infectious disease research. Frequently rodent models are used to study the pathobiology of these agents. Although much is known regarding naturally occurring infections in humans, less is documented on the sources of exposures and potential risks of infection to researchers and animal care personnel after the administration of these hazardous substances to laboratory animals. Failure to appropriately manage the animals can result both in the creation of workplace hazards if human exposures occur and in disruption of the research if unintended animal exposures occur. Here we review representative Category A agents, with a focus on comparing the biologic effects in naturally infected humans and rodent models and on considerations specific to the management of infected rodent subjects. The information reviewed for each agent has been curated manually and stored in a unique Internet-based database system called HazARD (Hazards in Animal Research Database, http://helab.bioinformatics.med.umich.edu/hazard/) that is designed to assist researchers, administrators, safety officials, Institutional Biosafety Committees, and veterinary personnel seeking information on the management of risks associated with animal studies involving hazardous substances.

  12. Strategies for generating multiple instances of common and ad hoc categories.

    PubMed

    Vallée-Tourangeau, F; Anthony, S H; Austin, N G

    1998-09-01

    In a free-emission procedure participants were asked to generate instances of a given category and to report, retrospectively, the strategies that they were aware of using in retrieving instances. In two studies reported here, participants generated instances for common categories (e.g. fruit) and for ad hoc categories (e.g., things people keep in their pockets) for 90 seconds and for each category described how they had proceeded in doing so. Analysis of the protocols identified three broad classes of strategy: (1) experiential, where memories of specific or generic personal experiences involving interactions with the category instances acted as cues; (2) semantic, where a consideration of abstract conceptual characteristics of a category were employed to retrieve category exemplars; (3) unmediated, where instances were effortlessly retrieved without mediating cognitions of which subjects were aware. Experiential strategies outnumbered semantic strategies (on average 4 to 1) not only for ad hoc categories but also for common categories. This pattern was noticeably reversed for ad hoc categories that subjects were unlikely to have experienced personally (e.g. things sold on the black market in Russia). Whereas more traditional accounts of semantic memory have favoured decontextualised abstract representations of category knowledge, to the extent that mode of access informs us of knowledge structures, our data suggest that category knowledge is significantly grounded in terms of everyday contexts where category instances are encountered.

  13. 20 CFR 402.155 - Fees to be charged-categories of requests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Fees to be charged-categories of requests. 402.155 Section 402.155 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.155 Fees to be charged—categories of requests. Paragraphs (a) through...

  14. 40 CFR 98.40 - Definition of the source category.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source category. (a) The electricity generation source category comprises electricity generating units that are subject to the requirements of the Acid Rain Program and any other electricity generating units that are...

  15. 40 CFR 98.40 - Definition of the source category.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source category. (a) The electricity generation source category comprises electricity generating units that are subject to the requirements of the Acid Rain Program and any other electricity generating units that are...

  16. 40 CFR 98.40 - Definition of the source category.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source category. (a) The electricity generation source category comprises electricity generating units that are subject to the requirements of the Acid Rain Program and any other electricity generating units that are...

  17. 40 CFR 98.40 - Definition of the source category.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source category. (a) The electricity generation source category comprises electricity generating units that are subject to the requirements of the Acid Rain Program and any other electricity generating units that are...

  18. 40 CFR 98.40 - Definition of the source category.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source category. (a) The electricity generation source category comprises electricity generating units that are subject to the requirements of the Acid Rain Program and any other electricity generating units that are...

  19. 28 CFR 25.4 - Record source categories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....4 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.4 Record source categories. It is anticipated that... to the NICS Index. Information in the NCIC and III systems that will be searched during a background...

  20. Influence of multiple categories on the prediction of unknown properties

    PubMed Central

    Verde, Michael F.; Murphy, Gregory L.; Ross, Brian H.

    2006-01-01

    Knowing an item's category helps us predict its unknown properties. Previous studies suggest that when asked to evaluate the probability of an unknown property, people tend to consider only an item's most likely category, ignoring alternative categories. In the present study, property prediction took the form of either a probability rating or a speeded, binary-choice judgment. Consistent with past findings, subjects ignored alternative categories in their probability ratings. However, their binary-choice judgments were influenced by alternative categories. This novel finding suggests that the way category knowledge is used in prediction depends critically on the form of the prediction. PMID:16156183

  1. Attitudes and evaluative practices: category vs. item and subjective vs. objective constructions in everyday food assessments.

    PubMed

    Wiggins, Sally; Potter, Jonathan

    2003-12-01

    In social psychology, evaluative expressions have traditionally been understood in terms of their relationship to, and as the expression of, underlying 'attitudes'. In contrast, discursive approaches have started to study evaluative expressions as part of varied social practices, considering what such expressions are doing rather than their relationship to attitudinal objects or other putative mental entities. In this study the latter approach will be used to examine the construction of food and drink evaluations in conversation. The data are taken from a corpus of family mealtimes recorded over a period of months. The aim of this study is to highlight two distinctions that are typically obscured in traditional attitude work ('subjective' vs. 'objective' expressions, category vs. item evaluations). A set of extracts is examined to document the presence of these distinctions in talk that evaluates food and the way they are used and rhetorically developed to perform particular activities (accepting/refusing food, complimenting the food provider, persuading someone to eat). The analysis suggests that researchers (a) should be aware of the potential significance of these distinctions; (b) should be cautious when treating evaluative terms as broadly equivalent and (c) should be cautious when blurring categories and instances. This analysis raises the broader question of how far evaluative practices may be specific to particular domains, and what this specificity might consist in. It is concluded that research in this area could benefit from starting to focus on the role of evaluations in practices and charting their association with specific topics and objects.

  2. 77 FR 48990 - Draft Guidance for Industry: Necessity of the Use of Food Categories in Food Facility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0585] Draft Guidance for Industry: Necessity of the Use of Food Categories in Food Facility Registrations and Updates to Food Categories; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

  3. Effect of Vaccine Administration Modality on Immunogenicity and Efficacy

    PubMed Central

    Zhang, Lu; Wang, Wei; Wang, Shixia

    2016-01-01

    Summary The many factors impacting the efficacy of a vaccine can be broadly divided into three categories: (1) features of the vaccine itself, including immunogen design, vaccine type, formulation, adjuvant, and dosing; (2) individual variations among vaccine recipients; and (3) vaccine administration-related parameters. While much literature exists related to vaccines, and recently systems biology has started to dissect the impact of individual subject variation on vaccine efficacy, few studies have focused on the role of vaccine administration-related parameters on vaccine efficacy. Parenteral and mucosal vaccinations are traditional approaches for licensed vaccines; novel vaccine delivery approaches, including needless injection and adjuvant formulations, are being developed to further improve vaccine safety and efficacy. This review provides a brief summary of vaccine administration-related factors, including vaccination approach, delivery route, and method of administration, to gain a better understanding of their potential impact on the safety and immunogenicity of candidate vaccines. PMID:26313239

  4. 12 CFR 702.302 - Net worth categories for new credit unions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Net worth categories for new credit unions. 702.302 Section 702.302 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS PROMPT CORRECTIVE ACTION Alternative Prompt Corrective Action for New Credit Unions § 702.302 Net worth categories for new credit unions....

  5. On Anaphora and the Binding Principles in Categorial Grammar

    NASA Astrophysics Data System (ADS)

    Morrill, Glyn; Valentín, Oriol

    In type logical categorial grammar the analysis of an expression is a resource-conscious proof. Anaphora represents a particular challenge to this approach in that the antecedent resource is multiplied in the semantics. This duplication, which corresponds logically to the structural rule of contraction, may be treated lexically or syntactically. Furthermore, anaphora is subject to constraints, which Chomsky (1981) formulated as Binding Principles A, B, and C. In this paper we consider English anaphora in categorial grammar including reference to the binding principles. We invoke displacement calculus, modal categorial calculus, categorial calculus with limited contraction, and entertain addition of negation as failure.

  6. 14 CFR 21.189 - Issue of airworthiness certificate for limited category aircraft.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Issue of airworthiness certificate for limited category aircraft. 21.189 Section 21.189 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Certificates § 21.189 Issue of airworthiness certificate for limited category aircraft. (a) An applicant for an...

  7. 14 CFR 21.189 - Issue of airworthiness certificate for limited category aircraft.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Issue of airworthiness certificate for limited category aircraft. 21.189 Section 21.189 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Certificates § 21.189 Issue of airworthiness certificate for limited category aircraft. (a) An applicant for an...

  8. 14 CFR 21.189 - Issue of airworthiness certificate for limited category aircraft.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Issue of airworthiness certificate for limited category aircraft. 21.189 Section 21.189 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Certificates § 21.189 Issue of airworthiness certificate for limited category aircraft. (a) An applicant for an...

  9. FDA pregnancy risk categories and the CPS

    PubMed Central

    Law, Ruth; Bozzo, Pina; Koren, Gideon; Einarson, Adrienne

    2010-01-01

    ABSTRACT QUESTION My patient is taking a medication for a chronic condition and has just found out that she is 6 weeks pregnant. The US Food and Drug Administration (FDA) has assigned this medication to pregnancy risk category D, and the Compendium of Pharmaceuticals and Specialties provides no additional data. How should I interpret this information, and how does the Motherisk Program evaluate the safety or risks of drug use in pregnancy? ANSWER Pregnancy safety data provided by the FDA pregnancy risk categories and the Compendium of Pharmaceuticals and Specialties are insufficient to guide clinical decisions on how to proceed with a pregnancy following exposure to a category D medication. The Motherisk Program creates peer-reviewed statements derived from the primary literature, and we examine fetal outcomes as well as the risk-benefit profile of maternal treatment when evaluating the safety of medication use in pregnancy. The FDA announced in May 2008 that it is dropping its pregnancy risk categories and adopting a method similar to the one we use at Motherisk. PMID:20228306

  10. Decoding Multiple Sound Categories in the Human Temporal Cortex Using High Resolution fMRI

    PubMed Central

    Zhang, Fengqing; Wang, Ji-Ping; Kim, Jieun; Parrish, Todd; Wong, Patrick C. M.

    2015-01-01

    Perception of sound categories is an important aspect of auditory perception. The extent to which the brain’s representation of sound categories is encoded in specialized subregions or distributed across the auditory cortex remains unclear. Recent studies using multivariate pattern analysis (MVPA) of brain activations have provided important insights into how the brain decodes perceptual information. In the large existing literature on brain decoding using MVPA methods, relatively few studies have been conducted on multi-class categorization in the auditory domain. Here, we investigated the representation and processing of auditory categories within the human temporal cortex using high resolution fMRI and MVPA methods. More importantly, we considered decoding multiple sound categories simultaneously through multi-class support vector machine-recursive feature elimination (MSVM-RFE) as our MVPA tool. Results show that for all classifications the model MSVM-RFE was able to learn the functional relation between the multiple sound categories and the corresponding evoked spatial patterns and classify the unlabeled sound-evoked patterns significantly above chance. This indicates the feasibility of decoding multiple sound categories not only within but across subjects. However, the across-subject variation affects classification performance more than the within-subject variation, as the across-subject analysis has significantly lower classification accuracies. Sound category-selective brain maps were identified based on multi-class classification and revealed distributed patterns of brain activity in the superior temporal gyrus and the middle temporal gyrus. This is in accordance with previous studies, indicating that information in the spatially distributed patterns may reflect a more abstract perceptual level of representation of sound categories. Further, we show that the across-subject classification performance can be significantly improved by averaging the f

  11. Decoding multiple sound categories in the human temporal cortex using high resolution fMRI.

    PubMed

    Zhang, Fengqing; Wang, Ji-Ping; Kim, Jieun; Parrish, Todd; Wong, Patrick C M

    2015-01-01

    Perception of sound categories is an important aspect of auditory perception. The extent to which the brain's representation of sound categories is encoded in specialized subregions or distributed across the auditory cortex remains unclear. Recent studies using multivariate pattern analysis (MVPA) of brain activations have provided important insights into how the brain decodes perceptual information. In the large existing literature on brain decoding using MVPA methods, relatively few studies have been conducted on multi-class categorization in the auditory domain. Here, we investigated the representation and processing of auditory categories within the human temporal cortex using high resolution fMRI and MVPA methods. More importantly, we considered decoding multiple sound categories simultaneously through multi-class support vector machine-recursive feature elimination (MSVM-RFE) as our MVPA tool. Results show that for all classifications the model MSVM-RFE was able to learn the functional relation between the multiple sound categories and the corresponding evoked spatial patterns and classify the unlabeled sound-evoked patterns significantly above chance. This indicates the feasibility of decoding multiple sound categories not only within but across subjects. However, the across-subject variation affects classification performance more than the within-subject variation, as the across-subject analysis has significantly lower classification accuracies. Sound category-selective brain maps were identified based on multi-class classification and revealed distributed patterns of brain activity in the superior temporal gyrus and the middle temporal gyrus. This is in accordance with previous studies, indicating that information in the spatially distributed patterns may reflect a more abstract perceptual level of representation of sound categories. Further, we show that the across-subject classification performance can be significantly improved by averaging the f

  12. Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects.

    PubMed

    Abbas, Richat; Hug, Bruce A; Leister, Cathie; Burns, Jaime; Sonnichsen, Daryl

    2011-04-01

    The primary objective was to evaluate the pharmacokinetics of a single dose of neratinib, a potent, low-molecular-weight, orally administered, irreversible pan-ErbB (ErbB-1, -2, -4) receptor tyrosine kinase inhibitor, during co-administration with ketoconazole, a potent CYP3A4 inhibitor. This was an open-label, randomized, two-period, crossover study. Fasting healthy adults received a single oral dose of neratinib 240 mg alone and with multiple oral doses of ketoconazole 400 mg. Blood samples were collected up to 72 h after each neratinib dose. Plasma concentration data were analyzed using a noncompartmental method. The least square geometric mean ratios [90% confidence interval (CI)] of C(max) (neratinib+ketoconazole): C(max) (neratinib alone), and AUC(neratinib+ketoconazole): AUC(neratinib alone) were assessed. Twenty-four subjects were enrolled. Compared with neratinib administered alone, co-administration of ketoconazole increased neratinib C(max) by 3.2-fold (90% CI: 2.4, 4.3) and AUC by 4.8-fold (3.6, 6.5). Median t(max) was 6.0 h with both regimens. Ketoconazole decreased mean apparent oral clearance of neratinib from 346 lh(-1) to 87.1 lh(-1) and increased mean elimination half-life from 11.7 h to 18.0 h. The incidence of adverse events was comparable between the two regimens (50% neratinib alone, 65% co-administration with ketoconazole). Co-administration of neratinib with ketoconazole, a potent CYP3A inhibitor, increased neratinib C(max) by 3.2-fold and AUC by 4.8-fold compared with administration of neratinib alone. These results indicate that neratinib is a substrate of CYP3A and is susceptible to interaction with potent CYP3A inhibitors and, thus, dose adjustments may be needed if neratinib is administered with such compounds. © 2011 The Authors. British Journal of Clinical Pharmacology © 2011 The British Pharmacological Society.

  13. Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects

    PubMed Central

    Abbas, Richat; Hug, Bruce A; Leister, Cathie; Burns, Jaime; Sonnichsen, Daryl

    2011-01-01

    AIM The primary objective was to evaluate the pharmacokinetics of a single dose of neratinib, a potent, low-molecular-weight, orally administered, irreversible pan-ErbB (ErbB-1, -2, -4) receptor tyrosine kinase inhibitor, during co-administration with ketoconazole, a potent CYP3A4 inhibitor. METHODS This was an open-label, randomized, two-period, crossover study. Fasting healthy adults received a single oral dose of neratinib 240 mg alone and with multiple oral doses of ketoconazole 400 mg. Blood samples were collected up to 72 h after each neratinib dose. Plasma concentration data were analyzed using a noncompartmental method. The least square geometric mean ratios [90% confidence interval (CI)] of Cmax(neratinib+ketoconazole) : Cmax(neratinib alone), and AUC(neratinib+ketoconazole) : AUC(neratinib alone) were assessed. RESULTS Twenty-four subjects were enrolled. Compared with neratinib administered alone, co-administration of ketoconazole increased neratinib Cmax by 3.2-fold (90% CI: 2.4, 4.3) and AUC by 4.8-fold (3.6, 6.5). Median tmax was 6.0 h with both regimens. Ketoconazole decreased mean apparent oral clearance of neratinib from 346 l h−1 to 87.1 l h−1 and increased mean elimination half-life from 11.7 h to 18.0 h. The incidence of adverse events was comparable between the two regimens (50% neratinib alone, 65% co-administration with ketoconazole). CONCLUSION Co-administration of neratinib with ketoconazole, a potent CYP3A inhibitor, increased neratinib Cmax by 3.2-fold and AUC by 4.8-fold compared with administration of neratinib alone. These results indicate that neratinib is a substrate of CYP3A and is susceptible to interaction with potent CYP3A inhibitors and, thus, dose adjustments may be needed if neratinib is administered with such compounds. PMID:21395644

  14. 14 CFR 21.189 - Issue of airworthiness certificate for limited category aircraft.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Issue of airworthiness certificate for limited category aircraft. 21.189 Section 21.189 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... a condition for safe operation. (b) The Administrator prescribes limitations and conditions...

  15. 14 CFR 21.189 - Issue of airworthiness certificate for limited category aircraft.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Issue of airworthiness certificate for limited category aircraft. 21.189 Section 21.189 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... a condition for safe operation. (b) The Administrator prescribes limitations and conditions...

  16. [The nurse's perceptions on administrative actions in their work process].

    PubMed

    Vaghetti, Helena; Reis, Daniela; Kerber, Nalú da Costa; Azambuja, Eliana; Fernandes, Geani

    2004-01-01

    A qualitative, exploratory study carried out from March to December 2002 in a university hospital based in the far south of the country, which aimed at identifying the nurses' perception on the administrative actions exercised in their daily work. Thematic categories emerged from data survey and content analysis in the interviews carried out with 10 nurses. We emphasize Category I: Administrative Actions as a Management Instrument; and Category II: Administrative Actions as Direct/indirect Care. In the first one, administrative actions are perceived as planning, coordination, leadership, control, information retention, and organization; the second one depicts administrative actions as an integral part of nursing care. It has been observed that many administrative actions exercised by nurses are inherent to their role, in keeping with the Nurse's Professional Exercise Code, and they are critical for care.

  17. 14 CFR 91.193 - Certificate of authorization for certain Category II operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Certificate of authorization for certain Category II operations. 91.193 Section 91.193 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... operations. The Administrator may issue a certificate of authorization authorizing deviations from the...

  18. A Multilevel Structural Equation Model of Within- and Between-Person Associations among Subjective Responses to Alcohol, Craving, and Laboratory Alcohol Self-Administration

    PubMed Central

    Wardell, Jeffrey D.; Ramchandani, Vijay A.; Hendershot, Christian S.

    2017-01-01

    Subjective responses to alcohol are important determinants of drinking behavior and have been linked with risk for alcohol use disorders. However, few attempts have been made to examine proximal within-person associations among state changes in subjective responses and ongoing alcohol self-administration in the laboratory. This study disaggregated within- and between-person associations among subjective responses and alcohol self-administration, while also examining the mediating role of craving and the moderating role of trait impaired control over alcohol. Sixty young heavy drinkers (mean age=19.90, SD=0.86) completed self-report measures including the Impaired Control Scale, then participated in a 2-hour intravenous alcohol self-administration session using the Computer-Assisted Self-infusion of Ethanol (CASE) paradigm. Repeated assessments of subjective stimulation, subjective sedation, and craving were examined in relation to ongoing in-session self-administration, as indexed by breath alcohol concentration (BrAC) assessed 15 minutes later. Multilevel structural equation modeling was used to disentangle within-person and between-person associations. The results showed few significant associations at the between-person level, except for a direct negative association between sedation and BrAC. At the within-person level, state fluctuations in stimulation were positively associated with both craving and subsequent BrAC, whereas state changes in sedation were negatively associated with craving and positively associated with BrAC. Within-person indirect associations from subjective stimulation and sedation to subsequent BrAC mediated via craving were statistically significant. Also, participants higher on impaired control showed stronger within-person associations between craving and greater subsequent BrAC. The results suggest that subjective responses to alcohol and craving have proximal associations with self-administration behavior, the strength of which is

  19. 14 CFR 36.7 - Acoustical change: Transport category large airplanes and jet airplanes.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... airplanes and jet airplanes. 36.7 Section 36.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... § 36.7 Acoustical change: Transport category large airplanes and jet airplanes. (a) Applicability. This section applies to all transport category large airplanes and jet airplanes for which an acoustical change...

  20. 14 CFR 36.7 - Acoustical change: Transport category large airplanes and jet airplanes.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... airplanes and jet airplanes. 36.7 Section 36.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... § 36.7 Acoustical change: Transport category large airplanes and jet airplanes. (a) Applicability. This section applies to all transport category large airplanes and jet airplanes for which an acoustical change...

  1. 14 CFR 36.7 - Acoustical change: Transport category large airplanes and jet airplanes.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... airplanes and jet airplanes. 36.7 Section 36.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... § 36.7 Acoustical change: Transport category large airplanes and jet airplanes. (a) Applicability. This section applies to all transport category large airplanes and jet airplanes for which an acoustical change...

  2. 47 CFR 61.42 - Price cap baskets and service categories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Price cap baskets and service categories. 61.42... (CONTINUED) TARIFFS General Rules for Dominant Carriers § 61.42 Price cap baskets and service categories. (a)-(c) [Reserved] (d) Each local exchange carrier subject to price cap regulation shall establish...

  3. 14 CFR 135.377 - Large transport category airplanes: Reciprocating engine powered: Landing limitations: Alternate...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Large transport category airplanes... Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS AND... Limitations § 135.377 Large transport category airplanes: Reciprocating engine powered: Landing limitations...

  4. 7 CFR 276.4 - Suspension/disallowance of administrative funds.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Section 276.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... share of one or more of the cost categories of a State agency's budget for administration of the Food... in one or more of the cost categories of a State agency's budget for Program administration. (2) In...

  5. 7 CFR 276.4 - Suspension/disallowance of administrative funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 276.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... share of one or more of the cost categories of a State agency's budget for administration of the Food... in one or more of the cost categories of a State agency's budget for Program administration. (2) In...

  6. 30 CFR 57.22003 - Mine category or subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Mine category or subcategory. 57.22003 Section 57.22003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND...— (A) A concentration of 0.25 percent or more methane has been detected in the mine atmosphere and...

  7. Category Coherence and Category-Based Property Induction

    ERIC Educational Resources Information Center

    Rehder, Bob; Hastie, Reid

    2004-01-01

    One important property of human object categories is that they define the sets of exemplars to which newly observed properties are generalized. We manipulated the causal knowledge associated with novel categories and assessed the resulting strength of property inductions. We found that the theoretical coherence afforded to a category by…

  8. Feature-based versus category-based induction with uncertain categories.

    PubMed

    Griffiths, Oren; Hayes, Brett K; Newell, Ben R

    2012-05-01

    Previous research has suggested that when feature inferences have to be made about an instance whose category membership is uncertain, feature-based inductive reasoning is used to the exclusion of category-based induction. These results contrast with the observation that people can and do use category-based induction when category membership is known. The present experiments examined the conditions that drive feature-based and category-based strategies in induction under category uncertainty. Specifically, 2 experiments investigated whether reliance on feature-based inductive strategies is a product of the lack of coherence in the categories used in previous research or is due to the use of a decision-only induction procedure. Experiment 1 found that feature-based reasoning remained the preferred strategy even when categories with relatively high internal coherence were used. Experiment 2 found a shift toward category-based reasoning when participants were trained to classify category members prior to feature induction. Together, these results suggest that an appropriate conceptual representation must be formed through experience with a category before it is likely to be used as a basis for feature induction. (c) 2012 APA, all rights reserved.

  9. Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.

    PubMed

    Paech, Gemma M; Banks, Siobhan; Pajcin, Maja; Grant, Crystal; Johnson, Kayla; Kamimori, Gary H; Vedova, Chris B Della

    2016-06-01

    The current study investigated the effects of repeated caffeine administration on performance and subjective reports of sleepiness and fatigue during 50h extended wakefulness. Twenty-four, non-smokers aged 22.5±2.9y (mean±SD) remained awake for two nights (50h) in a controlled laboratory environment. During this period, 200mg of caffeine or placebo gum was administered at 01:00, 03:00, 05:00 and 07:00 on both nights (total of 800mg/night). Neurobehavioral performance and subjective reports were assessed throughout the wake period. Caffeine improved performance compared to placebo, but did not affect overall ratings of subjective sleepiness and fatigue. Performance and sleepiness worsened with increasing time awake for both conditions. However, caffeine slowed performance impairments such that after 50h of wakefulness performance was better following caffeine administration compared to placebo. Caffeine also slowed the increase in subjective sleepiness and performance ratings, but only during the first night of wakefulness. After two nights of sleep deprivation, there was no difference in sleepiness ratings between the two conditions. These results demonstrate that strategic administration of caffeine effectively mitigates performance impairments associated with 50h wakefulness but does not improve overall subjective assessments of sleepiness, fatigue and performance. Results indicate that while performance impairment is alleviated, individuals may continue to report feelings of sleepiness. Individuals who use caffeine as a countermeasure in sustained operations may feel as though caffeine is not effective despite impairments in objective performance being largely mitigated. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Early warning reporting categories analysis of recall and complaints data.

    DOT National Transportation Integrated Search

    2001-12-31

    This analysis was performed to assist the National Highway Traffic Safety Administration (NHTSA) in identifying components and systems to be included in early warning reporting (EWR) categories that would be based upon historical safety-related recal...

  11. 76 FR 81790 - Airworthiness Standards: Transport Category Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... FEDERAL AVIATION ADMINISTRATION 14 CFR Part 25 Airworthiness Standards: Transport Category Airplanes CFR Correction In Title 14 of the Code of Federal Regulations, Parts 1 to 59, revised as of January 1, 2011, on page 413, in Sec. 25.509, in paragraph (a)(3)(ii), the expression ``(6W T + 450,000)/7...

  12. Molecular Monitoring of the Fecal Microbiota of Healthy Human Subjects during Administration of Lactulose and Saccharomyces boulardii

    PubMed Central

    Vanhoutte, Tom; De Preter, Vicky; De Brandt, Evie; Verbeke, Kristin; Swings, Jean; Huys, Geert

    2006-01-01

    Diet is a major factor in maintaining a healthy human gastrointestinal tract, and this has triggered the development of functional foods containing a probiotic and/or prebiotic component intended to improve the host's health via modulation of the intestinal microbiota. In this study, a long-term placebo-controlled crossover feeding study in which each subject received several treatments was performed to monitor the effect of a prebiotic substrate (i.e., lactulose), a probiotic organism (i.e., Saccharomyces boulardii), and their synbiotic combination on the fecal microbiota of three groups of 10 healthy human subjects differing in prebiotic dose and/or intake of placebo versus synbiotic. For this purpose, denaturing gradient gel electrophoresis (DGGE) analysis of 16S rRNA gene amplicons was used to detect possible changes in the overall bacterial composition using the universal V3 primer and to detect possible changes at the subpopulation level using group-specific primers targeting the Bacteroides fragilis subgroup, the genus Bifidobacterium, the Clostridium lituseburense group (cluster XI), and the Clostridium coccoides-Eubacterium rectale group (cluster XIVa). Although these populations remained fairly stable based on DGGE profiling, one pronounced change was observed in the universal fingerprint profiles after lactulose ingestion. Band position analysis and band sequencing revealed that a band appearing or intensifying following lactulose administration could be assigned to the species Bifidobacterium adolescentis. Subsequent analysis with real-time PCR (RT-PCR) indicated a statistically significant increase (P < 0.05) in total bifidobacteria in one of the three subject groups after lactulose administration, whereas a similar but nonsignificant trend was observed in the other two groups. Combined RT-PCR results from two subject groups indicated a borderline significant increase (P = 0.074) of B. adolescentis following lactulose intake. The probiotic yeast S

  13. Event-Related fMRI of Category Learning: Differences in Classification and Feedback Networks

    ERIC Educational Resources Information Center

    Little, Deborah M.; Shin, Silvia S.; Sisco, Shannon M.; Thulborn, Keith R.

    2006-01-01

    Eighteen healthy young adults underwent event-related (ER) functional magnetic resonance imaging (fMRI) of the brain while performing a visual category learning task. The specific category learning task required subjects to extract the rules that guide classification of quasi-random patterns of dots into categories. Following each classification…

  14. Aging and the Category-Recall Relationship.

    ERIC Educational Resources Information Center

    Worden, Patricia E.; Meggison, David L.

    A sorting-recall procedure was used to investigate how long-term memory in elderly subjects is affected by categorical organization. Sixty-four young adults (average age 20 years) and retirees (average age 67) sorted 48 unrelated words into two, four, six, or eight categories prior to recall. High- and low-frequency lists were tested, a…

  15. Typicality effects in artificial categories: is there a hemisphere difference?

    PubMed

    Richards, L G; Chiarello, C

    1990-07-01

    In category classification tasks, typicality effects are usually found: accuracy and reaction time depend upon distance from a prototype. In this study, subjects learned either verbal or nonverbal dot pattern categories, followed by a lateralized classification task. Comparable typicality effects were found in both reaction time and accuracy across visual fields for both verbal and nonverbal categories. Both hemispheres appeared to use a similarity-to-prototype matching strategy in classification. This indicates that merely having a verbal label does not differentiate classification in the two hemispheres.

  16. Effects of Task and Category Membership on Representation Stability

    ERIC Educational Resources Information Center

    Gaillard, Audrey; Urdapilleta, Isabel; Houix, Olivier; Manetta, Celine

    2011-01-01

    This study examined the within-subject stability of 150 participants who performed both a sorting task and a property-generation task over multiple sessions, focusing on three concrete concept categories (food, animals and bathroom products). We hypothesized that (1) the within-subject stability would be higher in the sorting task than in the…

  17. The development of automaticity in short-term memory search: Item-response learning and category learning.

    PubMed

    Cao, Rui; Nosofsky, Robert M; Shiffrin, Richard M

    2017-05-01

    In short-term-memory (STM)-search tasks, observers judge whether a test probe was present in a short list of study items. Here we investigated the long-term learning mechanisms that lead to the highly efficient STM-search performance observed under conditions of consistent-mapping (CM) training, in which targets and foils never switch roles across trials. In item-response learning, subjects learn long-term mappings between individual items and target versus foil responses. In category learning, subjects learn high-level codes corresponding to separate sets of items and learn to attach old versus new responses to these category codes. To distinguish between these 2 forms of learning, we tested subjects in categorized varied mapping (CV) conditions: There were 2 distinct categories of items, but the assignment of categories to target versus foil responses varied across trials. In cases involving arbitrary categories, CV performance closely resembled standard varied-mapping performance without categories and departed dramatically from CM performance, supporting the item-response-learning hypothesis. In cases involving prelearned categories, CV performance resembled CM performance, as long as there was sufficient practice or steps taken to reduce trial-to-trial category-switching costs. This pattern of results supports the category-coding hypothesis for sufficiently well-learned categories. Thus, item-response learning occurs rapidly and is used early in CM training; category learning is much slower but is eventually adopted and is used to increase the efficiency of search beyond that available from item-response learning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  18. Exercise Administrator Administrative Instructions for Age Classes 1, 2 & 3. Year 11, October 1979-May 1980.

    ERIC Educational Resources Information Center

    Research Triangle Inst., Durham, NC.

    This manual for Exercise Administrators of the National Assessment of Educational Progress; Second Literature Third Reading Assessment, consists of administrative instructions for use immediately preceding, during and after assessment sessions in schools. Definitions of racial/ethnic categories, associated codes, and guidelines for solicting…

  19. 41 CFR 105-60.501 - Categories of records exempt from disclosure under the FOIA.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Categories of records... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 60-PUBLIC AVAILABILITY OF AGENCY RECORDS AND INFORMATIONAL...

  20. 41 CFR 105-60.501 - Categories of records exempt from disclosure under the FOIA.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Categories of records... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 60-PUBLIC AVAILABILITY OF AGENCY RECORDS AND INFORMATIONAL...

  1. 41 CFR 105-60.501 - Categories of records exempt from disclosure under the FOIA.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Categories of records... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 60-PUBLIC AVAILABILITY OF AGENCY RECORDS AND INFORMATIONAL...

  2. 41 CFR 105-60.501 - Categories of records exempt from disclosure under the FOIA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Categories of records... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 60-PUBLIC AVAILABILITY OF AGENCY RECORDS AND INFORMATIONAL...

  3. Functional categories in agrammatism: evidence from Greek.

    PubMed

    Stavrakaki, Stavroula; Kouvava, Sofia

    2003-07-01

    The aim of this study is twofold. First, to investigate the use of functional categories by two Greek agrammatic aphasics. Second, to discuss the implications of our findings for the characterization of the deficit in agrammatism. The functional categories under investigation were the following: definite and indefinite articles, personal pronouns, aspect, tense, subject-verb agreement, wh-pronouns, complementizers and the mood marker na (=to). Based on data collected through different methods, it is argued that the deficit in agrammatism cannot be described in terms of a structural account but rather by means of difficulties in the implementation of grammatical knowledge.

  4. 14 CFR 135.369 - Large transport category airplanes: Reciprocating engine powered: En route limitations: All...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Large transport category airplanes... and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS AND... Limitations § 135.369 Large transport category airplanes: Reciprocating engine powered: En route limitations...

  5. 21 CFR 20.101 - Administrative enforcement records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Administrative enforcement records. 20.101 Section 20.101 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.101 Administrative enforcement...

  6. Subjective and physiological effects, and expired carbon monoxide concentrations in frequent and occasional cannabis smokers following smoked, vaporized, and oral cannabis administration.

    PubMed

    Newmeyer, Matthew N; Swortwood, Madeleine J; Abulseoud, Osama A; Huestis, Marilyn A

    2017-06-01

    Although smoking is the most common cannabis administration route, vaporization and consumption of cannabis edibles are common. Few studies directly compare cannabis' subjective and physiological effects following multiple administration routes. Subjective and physiological effects, and expired carbon monoxide (CO) were evaluated in frequent and occasional cannabis users following placebo (0.001% Δ 9 -tetrahydrocannabinol [THC]), smoked, vaporized, and oral cannabis (6.9% THC, ∼54mg). Participants' subjective ratings were significantly elevated compared to placebo after smoking and vaporization, while only occasional smokers' ratings were significantly elevated compared to placebo after oral dosing. Frequent smokers' maximum ratings were significantly different between inhaled and oral routes, while no differences in occasional smokers' maximum ratings between active routes were observed. Additionally, heart rate increases above baseline 0.5h after smoking (mean 12.2bpm) and vaporization (10.7bpm), and at 1.5h (13.0bpm) and 3h (10.2bpm) after oral dosing were significantly greater than changes after placebo, with no differences between frequent and occasional smokers. Finally, smoking produced significantly increased expired CO concentrations 0.25-6h post-dose compared to vaporization. All participants had significant elevations in subjective effects after smoking and vaporization, but only occasional smokers after oral cannabis, indicating partial tolerance to subjective effects with frequent exposure. There were no differences in occasional smokers' maximum subjective ratings across the three active administration routes. Vaporized cannabis is an attractive alternative for medicinal administrations over smoking or oral routes; effects occur quickly and doses can be titrated with minimal CO exposure. These results have strong implications for safety and abuse liability assessments. Published by Elsevier B.V.

  7. More than words: Adults learn probabilities over categories and relationships between them.

    PubMed

    Hudson Kam, Carla L

    2009-04-01

    This study examines whether human learners can acquire statistics over abstract categories and their relationships to each other. Adult learners were exposed to miniature artificial languages containing variation in the ordering of the Subject, Object, and Verb constituents. Different orders (e.g. SOV, VSO) occurred in the input with different frequencies, but the occurrence of one order versus another was not predictable. Importantly, the language was constructed such that participants could only match the overall input probabilities if they were tracking statistics over abstract categories, not over individual words. At test, participants reproduced the probabilities present in the input with a high degree of accuracy. Closer examination revealed that learner's were matching the probabilities associated with individual verbs rather than the category as a whole. However, individual nouns had no impact on word orders produced. Thus, participants learned the probabilities of a particular ordering of the abstract grammatical categories Subject and Object associated with each verb. Results suggest that statistical learning mechanisms are capable of tracking relationships between abstract linguistic categories in addition to individual items.

  8. Feature-Based versus Category-Based Induction with Uncertain Categories

    ERIC Educational Resources Information Center

    Griffiths, Oren; Hayes, Brett K.; Newell, Ben R.

    2012-01-01

    Previous research has suggested that when feature inferences have to be made about an instance whose category membership is uncertain, feature-based inductive reasoning is used to the exclusion of category-based induction. These results contrast with the observation that people can and do use category-based induction when category membership is…

  9. NASA aerospace database subject scope: An overview

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Outlined here is the subject scope of the NASA Aerospace Database, a publicly available subset of the NASA Scientific and Technical (STI) Database. Topics of interest to NASA are outlined and placed within the framework of the following broad aerospace subject categories: aeronautics, astronautics, chemistry and materials, engineering, geosciences, life sciences, mathematical and computer sciences, physics, social sciences, space sciences, and general. A brief discussion of the subject scope is given for each broad area, followed by a similar explanation of each of the narrower subject fields that follow. The subject category code is listed for each entry.

  10. Public science policy and administration. [cooperation of government industry, foundations, and educational institutions

    NASA Technical Reports Server (NTRS)

    Rosenthal, A. H. (Editor)

    1973-01-01

    Science, the overwhelming concern of our time, is no longer a matter of private research and development but one of public policy and administration, in which government, industry, foundations, and educational institutions must all work together as never before. Few other single tasks are of such decisive importance to the collective and individual welfare of American citizens as the formulation of public science policy and the administration of scientific programs. Eleven national authorities of varied background in science, education, and government administration contribute their experience and their judgment in an effort to deal with the major aspects of the subject. Their focus is on the meeting of actual problems; they consider the decision making process in both public and public-private organizations. Topics are grouped in three general categories: personnel needs and resources, organizational problems and techniques, and the administrative role in policy leadership.

  11. 14 CFR 135.389 - Large nontransport category airplanes: Takeoff limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Large nontransport category airplanes: Takeoff limitations. 135.389 Section 135.389 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... ON BOARD SUCH AIRCRAFT Airplane Performance Operating Limitations § 135.389 Large nontransport...

  12. 14 CFR 135.389 - Large nontransport category airplanes: Takeoff limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Large nontransport category airplanes: Takeoff limitations. 135.389 Section 135.389 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... ON BOARD SUCH AIRCRAFT Airplane Performance Operating Limitations § 135.389 Large nontransport...

  13. A normal' category-specific advantage for naming living things.

    PubMed

    Laws, K R; Neve, C

    1999-10-01

    'Artefactual' accounts of category-specific disorders for living things have highlighted that compared to nonliving things, living things have lower name frequency, lower concept familiarity and greater visual complexity and greater within-category structural similarity or 'visual crowding' [7]. These hypotheses imply that deficits for living things are an exaggeration of some 'normal tendency'. Contrary to these notions, we found that normal subjects were consistently worse at naming nonliving than living things in a speeded presentation paradigm. Moreover, their naming was not predicted by concept familiarity, name frequency or visual complexity; however, a novel measure of visual familiarity (i.e. for the appearance of things) did significantly predict naming. We propose that under speeded conditions, normal subjects find nonliving things harder to name because their representations are less visually predictable than for living things (i.e. nonliving things show greater within-item structural variability). Finally, because nonliving things have multiple representations in the real world, this may lower the probability of finding impaired naming and recognition in this category.

  14. On Learning Natural-Science Categories That Violate the Family-Resemblance Principle.

    PubMed

    Nosofsky, Robert M; Sanders, Craig A; Gerdom, Alex; Douglas, Bruce J; McDaniel, Mark A

    2017-01-01

    The general view in psychological science is that natural categories obey a coherent, family-resemblance principle. In this investigation, we documented an example of an important exception to this principle: Results of a multidimensional-scaling study of igneous, metamorphic, and sedimentary rocks (Experiment 1) suggested that the structure of these categories is disorganized and dispersed. This finding motivated us to explore what might be the optimal procedures for teaching dispersed categories, a goal that is likely critical to science education in general. Subjects in Experiment 2 learned to classify pictures of rocks into compact or dispersed high-level categories. One group learned the categories through focused high-level training, whereas a second group was required to simultaneously learn classifications at a subtype level. Although high-level training led to enhanced performance when the categories were compact, subtype training was better when the categories were dispersed. We provide an interpretation of the results in terms of an exemplar-memory model of category learning.

  15. 14 CFR Appendix A to Part 91 - Category II Operations: Manual, Instruments, Equipment, and Maintenance

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... authorization for the type aircraft checked. (3) A schedule that provides for the performance of bench checks..., Equipment, and Maintenance A Appendix A to Part 91 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Maintenance 1. Category II Manual (a) Application for approval. An applicant for approval of a Category II...

  16. 14 CFR Appendix A to Part 91 - Category II Operations: Manual, Instruments, Equipment, and Maintenance

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... authorization for the type aircraft checked. (3) A schedule that provides for the performance of bench checks..., Equipment, and Maintenance A Appendix A to Part 91 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Maintenance 1. Category II Manual (a) Application for approval. An applicant for approval of a Category II...

  17. 14 CFR Appendix A to Part 91 - Category II Operations: Manual, Instruments, Equipment, and Maintenance

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... authorization for the type aircraft checked. (3) A schedule that provides for the performance of bench checks..., Equipment, and Maintenance A Appendix A to Part 91 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Maintenance 1. Category II Manual (a) Application for approval. An applicant for approval of a Category II...

  18. 14 CFR Appendix A to Part 91 - Category II Operations: Manual, Instruments, Equipment, and Maintenance

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... authorization for the type aircraft checked. (3) A schedule that provides for the performance of bench checks..., Equipment, and Maintenance A Appendix A to Part 91 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Maintenance 1. Category II Manual (a) Application for approval. An applicant for approval of a Category II...

  19. 14 CFR Appendix A to Part 91 - Category II Operations: Manual, Instruments, Equipment, and Maintenance

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authorization for the type aircraft checked. (3) A schedule that provides for the performance of bench checks..., Equipment, and Maintenance A Appendix A to Part 91 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Maintenance 1. Category II Manual (a) Application for approval. An applicant for approval of a Category II...

  20. Effects of classification context on categorization in natural categories.

    PubMed

    Hampton, James A; Dubois, Danièle; Yeh, Wenchi

    2006-10-01

    The patterns of classification of borderline instances of eight common taxonomic categories were examined under three different instructional conditions to test two predictions: first, that lack of a specified context contributes to vagueness in categorization, and second, that altering the purpose of classification can lead to greater or lesser dependence on similarity in classification. The instructional conditions contrasted purely pragmatic with more technical/quasi-legal contexts as purposes for classification, and these were compared with a no-context control. The measures of category vagueness were between-subjects disagreement and within-subjects consistency, and the measures of similarity-based categorization were category breadth and the correlation of instance categorization probability with mean rated typicality, independently measured in a neutral context. Contrary to predictions, none of the measures of vagueness, reliability, category breadth, or correlation with typicality were generally affected by the instructional setting as a function of pragmatic versus technical purposes. Only one subcondition, in which a situational context was implied in addition to a purposive context, produced a significant change in categorization. Further experiments demonstrated that the effect of context was not increased when participants talked their way through the task, and that a technical context did not elicit more all-or-none categorization than did a pragmatic context. These findings place an important boundary condition on the effects of instructional context on conceptual categorization.

  1. Family Factors Predicting Categories of Suicide Risk

    ERIC Educational Resources Information Center

    Randell, Brooke P.; Wang, Wen-Ling; Herting, Jerald R.; Eggert, Leona L.

    2006-01-01

    We compared family risk and protective factors among potential high school dropouts with and without suicide-risk behaviors (SRB) and examined the extent to which these factors predict categories of SRB. Subjects were randomly selected from among potential dropouts in 14 high schools. Based upon suicide-risk status, 1,083 potential high school…

  2. Another Look at Administrators: Dodgers to Masters.

    ERIC Educational Resources Information Center

    Ludewig, Larry M.

    1983-01-01

    Presents a tongue-in-cheek system for classifying educational administrators into four categories (Artful Dodger, Commander in Chief, Leader of the Pack, and Facilitating Master) according to leadership style and administrator characteristics. A brief sampler survey is included. (JAC)

  3. Empire: An Analytical Category for Educational Research

    ERIC Educational Resources Information Center

    Coloma, Roland Sintos

    2013-01-01

    In this article Roland Sintos Coloma argues for the relevance of empire as an analytical category in educational research. He points out the silence in mainstream studies of education on the subject of empire, the various interpretive approaches to deploying empire as an analytic, and the importance of indigeneity in research on empire and…

  4. A Category Mistake: Why Contemporary Australian Religious Education in Catholic Schools May Be Doomed to Failure

    ERIC Educational Resources Information Center

    Hyde, Brendan

    2013-01-01

    Assuming religious education to be the same as other subject areas of a Catholic school's curriculum by, for example, applying the outcomes based philosophy and language of other subject areas to religious education renders a category mistake. A prominent notion in the work of metaphysical philosopher Gilbert Ryle, a category mistake arises when…

  5. [Categories of alcohol consumers and the criteria for classification].

    PubMed

    Herrán, Oscar F; Ardila, María F

    2009-12-01

    The consequences of alcohol intake can be public health problems. A well-constructed classification system of alcohol consumers will assist in designing strategies for mitigation and control of alcohol-induced behaviors. A categorization of alcohol consumers was developed based on a set of consumer-associated variables. A set of 1,199 subjects between 18 and 60 years old was selected and each subject classified in three categories of alcohol intake: type A, intake desirable; type B, excessive consumption without related problems; and type C, problematic consumption or dependence. Using multinomial logistic regression model, the decisive variables of each category were fixed. Subject with positive expectations associated with consumption such as increase in expressivity and the sexuality have 1.6 (95% CI; 1.0 - 2.5) times greater probability to be placed in the C category that those without those expectations. For relationships associated with inhibition and feelings of power, this risk even greater- 2.2 (95%CI; 1.1- 4.3). Age is in an inverse relationship and a protective factor to be classified type B or C. Men have a greater probability than women to be classes in B or C; this probability is the same as subjects who indicate having moderate pleasure or a rise in pleasure induced by the alcoholic drinks. The results can be translated into programs for interventions at the population level directed to groups of higher risk, such as scholars and preteens, and with a gender focus. The personality element on which to focus the intervention is that of self-esteem. This is an element built from a behavioral-cognitive perspective within the context of the social and cultural learning process.

  6. Decoding Visual Object Categories in Early Somatosensory Cortex

    PubMed Central

    Smith, Fraser W.; Goodale, Melvyn A.

    2015-01-01

    Neurons, even in the earliest sensory areas of cortex, are subject to a great deal of contextual influence from both within and across modality connections. In the present work, we investigated whether the earliest regions of somatosensory cortex (S1 and S2) would contain content-specific information about visual object categories. We reasoned that this might be possible due to the associations formed through experience that link different sensory aspects of a given object. Participants were presented with visual images of different object categories in 2 fMRI experiments. Multivariate pattern analysis revealed reliable decoding of familiar visual object category in bilateral S1 (i.e., postcentral gyri) and right S2. We further show that this decoding is observed for familiar but not unfamiliar visual objects in S1. In addition, whole-brain searchlight decoding analyses revealed several areas in the parietal lobe that could mediate the observed context effects between vision and somatosensation. These results demonstrate that even the first cortical stages of somatosensory processing carry information about the category of visually presented familiar objects. PMID:24122136

  7. Hemispheric differentiation and category width.

    PubMed

    Huang, M S

    1979-12-01

    This study concerns the relationship between a cognitive style dimension, category width, and hemispheric differentiation. When lists of word pairs were presented simultaneously in a dichotic listening task to broad and narrow categorisers (all female, right-handed), both groups of subjects recalled more words presented to the right ear than those presented to the left ear; indicating left hemisphere's superiority in verbal processing. Both broad and narrow categorisers recalled a similar number of words in the right ear (left hemisphere), but the former recalled significantly more words in the left ear than did the latter. This finding is interpreted as meaning that narrow categorisers rely predominantly on the left hemisphere in verbal processing, and that in comparison with narrow categories, there is greater right hemispheric involvement in processing in the case of broad categorisers. The implication of this finding in terms of the differential processing strategies adopted by the two groups of individuals is discussed.

  8. Semantic, perceptual and number space: relations between category width and spatial processing.

    PubMed

    Brugger, Peter; Loetscher, Tobias; Graves, Roger E; Knoch, Daria

    2007-05-17

    Coarse semantic encoding and broad categorization behavior are the hallmarks of the right cerebral hemisphere's contribution to language processing. We correlated 40 healthy subjects' breadth of categorization as assessed with Pettigrew's category width scale with lateral asymmetries in perceptual and representational space. Specifically, we hypothesized broader category width to be associated with larger leftward spatial biases. For the 20 men, but not the 20 women, this hypothesis was confirmed both in a lateralized tachistoscopic task with chimeric faces and a random digit generation task; the higher a male participant's score on category width, the more pronounced were his left-visual field bias in the judgement of chimeric faces and his small-number preference in digit generation ("small" is to the left of "large" in number space). Subjects' category width was unrelated to lateral displacements in a blindfolded tactile-motor rod centering task. These findings indicate that visual-spatial functions of the right hemisphere should not be considered independent of the same hemisphere's contribution to language. Linguistic and spatial cognition may be more tightly interwoven than is currently assumed.

  9. Pharmacokinetics, Safety and Tolerability of Sacubitril/Valsartan (LCZ696) After Single-Dose Administration in Healthy Chinese Subjects.

    PubMed

    Han, Yi; Ayalasomayajula, Surya; Pan, Wei; Yang, Fan; Yuan, Yaozong; Langenickel, Thomas; Hinder, Markus; Kalluri, Sampath; Pal, Parasar; Sunkara, Gangadhar

    2017-02-01

    Sacubitril/valsartan (LCZ696) is a first-in-class angiotensin receptor neprilysin inhibitor (ARNI) and has been recently approved in several countries for the treatment of patients with heart failure and reduced ejection fraction. This was the first study conducted to characterise the pharmacokinetics of LCZ696 analytes (pro-drug sacubitril, active neprilysin inhibitor LBQ657 and valsartan) after single-dose administration of LCZ696 in healthy Chinese subjects. In this open-label, randomised, parallel-group study, following screening and baseline evaluation, eligible healthy subjects received single oral doses of LCZ696 50, 100, 200 or 400 mg. The pharmacokinetics, safety and tolerability of LCZ696 were assessed up to 72 h after dosing. A total of 40 healthy male subjects were enrolled, and all completed the study. Following oral administration, LCZ696 delivered systemic exposure to sacubitril, LBQ657 and valsartan with a median time to reach maximum plasma concentration (T max ) ranging from 0.50 to 1.25, 2.00 to 3.00 and 1.50 to 2.50 h, respectively, over the investigated dose range. The mean terminal elimination half-life (T 1/2 ) ranged from 0.89 to 1.35, 8.57 to 9.24 and 5.33 to 7.91 h for sacubitril, LBQ657 and valsartan, respectively. The area under the plasma concentration-time curve from time zero to the time of the last quantifiable concentration (AUC 0-last ), and maximum plasma concentration (C max ) for LBQ657 increased dose proportionally over the entire dose range. Dose linear increase in the exposure was observed across the dose range for sacubitril and valsartan. LCZ696 was safe and well tolerated at all doses in this study. Adverse events of only mild intensity, which required no treatment, were reported in 6 (15 %) subjects. The pharmacokinetic profiles of LCZ696 analytes in Chinese subjects are similar to those reported previously in Caucasian subjects.

  10. Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects.

    PubMed

    Laizure, S Casey; Meibohm, Bernd; Nelson, Kembral; Chen, Feng; Hu, Zhe-Yi; Parker, Robert B

    2017-12-01

    To determine the disposition and effects of caffeine after administration using a new dosage form (AeroShot) that delivers caffeine by inspiration of a fine powder into the oral cavity and compare it to an equivalent dose of an oral solution (energy drink) as the reference standard. Healthy human subjects (n = 17) inspired a 100 mg caffeine dose using the AeroShot device or consumed an energy drink on separate study days. Heart rate, blood pressure and subject assessments of effects were measured over an 8-h period. Plasma concentrations of caffeine and its major metabolites were determined by liquid chromatography-mass spectrometry. Pharmacokinetic, cardiovascular and perceived stimulant effects were compared between AeroShot and energy drink phases using a paired t test and standard bioequivalency analysis. Caffeine disposition was similar after caffeine administration by the AeroShot device and energy drink: peak plasma concentration 1790 and 1939 ng ml -1 , and area under the concentration-time curve (AUC) 15 579 and 17 569 ng ml -1 × h, respectively, but they were not bioequivalent: AeroShot AUC of 80.3% (confidence interval 71.2-104.7%) and peak plasma concentration of 86.3% (confidence interval 62.8-102.8%) compared to the energy drink. Female subjects did have a significantly larger AUC compared to males after consumption of the energy drink. The heart rate and blood pressure were not significantly affected by the 100 mg caffeine dose, and there were no consistently perceived stimulant effects by the subjects using visual analogue scales. Inspiration of caffeine as a fine powder using the AeroShot device produces a similar caffeine profile and effects compared to administration of an oral solution (energy drink). © 2017 The British Pharmacological Society.

  11. 14 CFR 21.25 - Issue of type certificate: Restricted category aircraft.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Issue of type certificate: Restricted category aircraft. 21.25 Section 21.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...; (3) Aerial surveying (photography, mapping, and oil and mineral exploration); (4) Patrolling...

  12. 14 CFR 21.25 - Issue of type certificate: Restricted category aircraft.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Issue of type certificate: Restricted category aircraft. 21.25 Section 21.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... conservation; (3) Aerial surveying (photography, mapping, and oil and mineral exploration); (4) Patrolling...

  13. 14 CFR 21.25 - Issue of type certificate: Restricted category aircraft.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Issue of type certificate: Restricted category aircraft. 21.25 Section 21.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...; (3) Aerial surveying (photography, mapping, and oil and mineral exploration); (4) Patrolling...

  14. 14 CFR 21.25 - Issue of type certificate: Restricted category aircraft.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Issue of type certificate: Restricted category aircraft. 21.25 Section 21.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...; (3) Aerial surveying (photography, mapping, and oil and mineral exploration); (4) Patrolling...

  15. 14 CFR 21.25 - Issue of type certificate: Restricted category aircraft.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Issue of type certificate: Restricted category aircraft. 21.25 Section 21.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... conservation; (3) Aerial surveying (photography, mapping, and oil and mineral exploration); (4) Patrolling...

  16. Pharmacokinetics of Caffeine following a Single Administration of Coffee Enema versus Oral Coffee Consumption in Healthy Male Subjects

    PubMed Central

    Tosri, Nisanuch; Rojanasthien, Noppamas; Srichairatanakool, Somdet; Sangdee, Chaichan

    2013-01-01

    The objective of this study was to determine the pharmacokinetics of caffeine after single administration of a coffee enema versus coffee consumed orally in healthy male subjects. The study design was an open-label, randomized two-phase crossover study. Eleven healthy subjects were randomly assigned either to receive 500 mL of coffee enema for 10 minutes or to consume 180 mL of ready-to-drink coffee beverage. After a washout period of at least 10 days, all the subjects were switched to receive the alternate coffee procedure. Blood samples were collected immediately before and at specific time points until 12 hours after coffee administration in each phase. The mean caffeine content in both the coffee solution prepared for the coffee enema and the ready-to-drink coffee beverage was not statistically different. The C max and AUC of caffeine obtained from the coffee enema were about 3.5 times significantly less than those of the coffee consumed orally, despite having slightly but statistically faster T max. The t 1/2 of caffeine obtained following both coffee procedures did not statistically differ. In summary, the relative bioavailability of caffeine obtained from the coffee enema was about 3.5 times significantly less than those of the coffee consumed orally. PMID:23533801

  17. Word-Category Violations in Patients with Broca's Aphasia: An ERP Study

    ERIC Educational Resources Information Center

    Wassenaar, Marlies; Hagoort, Peter

    2005-01-01

    An event-related brain potential experiment was carried out to investigate on-line syntactic processing in patients with Broca's aphasia. Subjects were visually presented with sentences that were either syntactically correct or contained violations of word-category. Three groups of subjects were tested: Broca patients (N=11), non-aphasic patients…

  18. Hands-free administration of subjective workload scales: acceptability in a surgical training environment.

    PubMed

    Carswell, C Melody; Lio, Cindy H; Grant, Russell; Klein, Martina I; Clarke, Duncan; Seales, W Brent; Strup, Stephen

    2010-12-01

    Subjective workload measures are usually administered in a visual-manual format, either electronically or by paper and pencil. However, vocal responses to spoken queries may sometimes be preferable, for example when experimental manipulations require continuous manual responding or when participants have certain sensory/motor impairments. In the present study, we evaluated the acceptability of the hands-free administration of two subjective workload questionnaires - the NASA Task Load Index (NASA-TLX) and the Multiple Resources Questionnaire (MRQ) - in a surgical training environment where manual responding is often constrained. Sixty-four undergraduates performed fifteen 90-s trials of laparoscopic training tasks (five replications of 3 tasks - cannulation, ring transfer, and rope manipulation). Half of the participants provided workload ratings using a traditional paper-and-pencil version of the NASA-TLX and MRQ; the remainder used a vocal (hands-free) version of the questionnaires. A follow-up experiment extended the evaluation of the hands-free version to actual medical students in a Minimally Invasive Surgery (MIS) training facility. The NASA-TLX was scored in 2 ways - (1) the traditional procedure using participant-specific weights to combine its 6 subscales, and (2) a simplified procedure - the NASA Raw Task Load Index (NASA-RTLX) - using the unweighted mean of the subscale scores. Comparison of the scores obtained from the hands-free and written administration conditions yielded coefficients of equivalence of r=0.85 (NASA-TLX) and r=0.81 (NASA-RTLX). Equivalence estimates for the individual subscales ranged from r=0.78 ("mental demand") to r=0.31 ("effort"). Both administration formats and scoring methods were equally sensitive to task and repetition effects. For the MRQ, the coefficient of equivalence for the hands-free and written versions was r=0.96 when tested on undergraduates. However, the sensitivity of the hands-free MRQ to task demands (

  19. Effect of repeated gaboxadol administration on night sleep and next-day performance in healthy elderly subjects.

    PubMed

    Mathias, Stefan; Zihl, Josef; Steiger, Axel; Lancel, Marike

    2005-04-01

    Aging is associated with dramatic reductions in sleep continuity and sleep intensity. Since gaboxadol, a selective GABA(A) receptor agonist, has been demonstrated to improve sleep consolidation and promote deep sleep, it may be an effective hypnotic, particularly for elderly patients with insomnia. In the present study, we investigated the effects of subchronic gaboxadol administration on nocturnal sleep and its residual effects during the next days in elderly subjects. This was a randomized, double-blind, placebo-controlled, balanced crossover study in 10 healthy elderly subjects without sleep complaints. The subjects were administered either placebo or 15 mg gaboxadol hydrochloride at bedtime on three consecutive nights. Sleep was recorded during each night from 2300 to 0700 h and tests assessing attention (target detection, stroop test) and memory function (visual form recognition, immediate word recall, digit span) were applied at 0900, 1400, and 1700 h during the following days. Compared with placebo, gaboxadol significantly shortened subjective sleep onset latency and increased self-rated sleep intensity and quality. Polysomnographic recordings showed that it significantly decreased the number of awakenings, the amount of intermittent wakefulness, and stage 1, and increased slow wave sleep and stage 2. These effects were stable over the three nights. None of the subjects reported side effects. Next-day cognitive performance was not affected by gaboxadol. Gaboxadol persistently improved subjective and objective sleep quality and was devoid of residual effects. Thus, at the employed dose, it seems an effective hypnotic in elderly subjects.

  20. Prescriptions for contraindicated category X drugs in pregnancy among women enrolled in TennCare.

    PubMed

    Cooper, William O; Hickson, Gerald B; Ray, Wayne A

    2004-03-01

    Filling of prescriptions for medications labelled as category X by the United States Food and Drug Administration (considered to be contraindicated for use in pregnancy) was identified among 95 284 women enrolled in TennCare, Tennessee's programme for Medicaid enrollees and individuals without health insurance. Using administrative claims data, 391 women (4.10/1000) were identified as having filled category X prescriptions during pregnancy. This included 118 women (1.24/1000) who filled prescriptions for non-contraceptive oestrogens, 81 (0.85/1000) for sedatives, and 71 (0.75/1000) for statins. While many women had physician visits with a diagnosis consistent with a possible indication for an individual drug outside of pregnancy, none of these indications is included for use during pregnancy. Older women and disabled women were more likely than younger women (P < 0.0001) and women enrolled for other reasons (P < 0.0001) to fill category X prescriptions. Nearly two-thirds of the 391 women filled prescriptions after clinical signs or pregnancy tests would indicate pregnancy; nearly 40% filled a category X prescription after a pregnancy-related physician visit. Although the absolute rate of category X medication use in pregnancy is low, substantial numbers of women and their fetuses are exposed during pregnancy. Women above the age of 35 years and women enrolled in TennCare because of disabilities were more likely to fill prescriptions for category X medications during pregnancy than others, implying that risk communication to practitioners and women should focus on identification of these women to reduce their risk of exposure.

  1. Comparison of subjective and fully automated methods for measuring mammographic density.

    PubMed

    Moshina, Nataliia; Roman, Marta; Sebuødegård, Sofie; Waade, Gunvor G; Ursin, Giske; Hofvind, Solveig

    2018-02-01

    Background Breast radiologists of the Norwegian Breast Cancer Screening Program subjectively classified mammographic density using a three-point scale between 1996 and 2012 and changed into the fourth edition of the BI-RADS classification since 2013. In 2015, an automated volumetric breast density assessment software was installed at two screening units. Purpose To compare volumetric breast density measurements from the automated method with two subjective methods: the three-point scale and the BI-RADS density classification. Material and Methods Information on subjective and automated density assessment was obtained from screening examinations of 3635 women recalled for further assessment due to positive screening mammography between 2007 and 2015. The score of the three-point scale (I = fatty; II = medium dense; III = dense) was available for 2310 women. The BI-RADS density score was provided for 1325 women. Mean volumetric breast density was estimated for each category of the subjective classifications. The automated software assigned volumetric breast density to four categories. The agreement between BI-RADS and volumetric breast density categories was assessed using weighted kappa (k w ). Results Mean volumetric breast density was 4.5%, 7.5%, and 13.4% for categories I, II, and III of the three-point scale, respectively, and 4.4%, 7.5%, 9.9%, and 13.9% for the BI-RADS density categories, respectively ( P for trend < 0.001 for both subjective classifications). The agreement between BI-RADS and volumetric breast density categories was k w  = 0.5 (95% CI = 0.47-0.53; P < 0.001). Conclusion Mean values of volumetric breast density increased with increasing density category of the subjective classifications. The agreement between BI-RADS and volumetric breast density categories was moderate.

  2. Some Reflections about Writing "A History of Thought and Practice in Educational Administration."

    ERIC Educational Resources Information Center

    Campbell, Roald F.

    A coauthor of a book on the history of thought and practice in educational administration reflects on issues raised during the writing of the book as follows: (1) Categories of administrative thought are difficult to establish. Two categories were derived from Richard Scott's rational systems approach--scientific management and bureaucracy. The…

  3. Using incident reports to inform the prevention of medication administration errors.

    PubMed

    Härkänen, Marja; Saano, Susanna; Vehviläinen-Julkunen, Katri

    2017-11-01

    To describe ways of preventing medication administration errors based on reporters' views expressed in medication administration incident reports. Medication administration errors are very common, and nurses play important roles in committing and in preventing such errors. Thus far, incident reporters' perceptions of how to prevent medication administration errors have rarely been analysed. This is a qualitative, descriptive study using an inductive content analysis of the incident reports related to medication administration errors (n = 1012). These free-text descriptions include reporters' views on preventing the reoccurrence of medication administration errors. The data were collected from two hospitals in Finland and pertain to incidents that were reported between 1 January 2013 and 31 December 2014. Reporters' views on preventing medication administration errors were divided into three main categories related to individuals (health professionals), teams and organisations. The following categories related to individuals in preventing medication administration errors were identified: (1) accuracy and preciseness; (2) verification; and (3) following the guidelines, responsibility and attitude towards work. The team categories were as follows: (1) distribution of work; (2) flow of information and cooperation; and (3) documenting and marking the drug information. The categories related to organisation were as follows: (1) work environment; (2) resources; (3) training; (4) guidelines; and (5) development of the work. Health professionals should administer medication with a high moral awareness and an attempt to concentrate on the task. Nonetheless, the system should support health professionals by providing a reasonable work environment and encouraging collaboration among the providers to facilitate the safe administration of medication. Although there are numerous approaches to supporting medication safety, approaches that support the ability of individual health

  4. 45 CFR 5.41 - Fees to be charged-categories of requests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Fees to be charged-categories of requests. 5.41 Section 5.41 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION FREEDOM OF... the costs of search, review, and duplication. (b) Educational and scientific institutions and news...

  5. 45 CFR 5.41 - Fees to be charged-categories of requests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Fees to be charged-categories of requests. 5.41 Section 5.41 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION FREEDOM OF... the costs of search, review, and duplication. (b) Educational and scientific institutions and news...

  6. 45 CFR 5.41 - Fees to be charged-categories of requests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Fees to be charged-categories of requests. 5.41 Section 5.41 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION FREEDOM OF... the costs of search, review, and duplication. (b) Educational and scientific institutions and news...

  7. Separating the Sheep from the Goats: Differentiating Global Categories.

    ERIC Educational Resources Information Center

    Mandler, Jean M.; And Others

    1991-01-01

    The conceptual categories that children have developed in their second year were studied in five experiments using object manipulation tasks. Subjects included 152 children from 18 to 31 months of age. These very young children had formed global conceptions of many domains of objects. (SLD)

  8. Category labels versus feature labels: category labels polarize inferential predictions.

    PubMed

    Yamauchi, Takashi; Yu, Na-Yung

    2008-04-01

    What makes category labels different from feature labels in predictive inference? This study suggests that category labels tend to make inductive reasoning polarized and homogeneous. In two experiments, participants were shown two schematic pictures of insects side by side and predicted the value of a hidden feature of one insect on the basis of the other insect. Arbitrary verbal labels were shown above the two pictures, and the meanings of the labels were manipulated in the instructions. In one condition, the labels represented the category membership of the insects, and in the other conditions, the same labels represented attributes of the insects. When the labels represented category membership, participants' responses became substantially polarized and homogeneous, indicating that the mere reference to category membership can modify reasoning processes.

  9. Report of Apollo 204 Review Board to the Administrator, National Aeronautics and Space Administration . Appendix F ; Schedule of Physical Evidence

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Immediately following the Apollo 204 accident of January 27, 1961. all associated equipment and material were impounded. Release of this equipment and material for normal use was under the close control of the Apollo 204 Review Board. Apollo Review Board Administrative Procedure No. 11, February 11, 1961, established the Apollo 204 Review Board Material Release Record (MRR). This MRR was the official form used to release material from full impoundment and was valid only after being approved by the Board and signed by a Member. The form was used as the authority to place any impounded item into one of the three Categories defined in Administrative Procedure No. 11. This appendix contains all of the authorized MRR's. Each item submitted on an MRR was given a control number; a description, including the part number and serial number; the relevance and location to the accident; any constraints before release; and the control category. The categories placed on the equipment were as follows: Category A - Items which may have a significant influence or bearing on the results or findings of the Apollo 204 Review Board; Category B - All material other than Category A which is considered relevant to the Apollo 204 Review Board investigation; Category C - Material released from Board jurisdiction. Several classes of equipment were released by special Board action prior to the establishment of the MRR system. The operating procedure for release of these classes is Enclosure F-l to this appendix.

  10. Decoding visual object categories in early somatosensory cortex.

    PubMed

    Smith, Fraser W; Goodale, Melvyn A

    2015-04-01

    Neurons, even in the earliest sensory areas of cortex, are subject to a great deal of contextual influence from both within and across modality connections. In the present work, we investigated whether the earliest regions of somatosensory cortex (S1 and S2) would contain content-specific information about visual object categories. We reasoned that this might be possible due to the associations formed through experience that link different sensory aspects of a given object. Participants were presented with visual images of different object categories in 2 fMRI experiments. Multivariate pattern analysis revealed reliable decoding of familiar visual object category in bilateral S1 (i.e., postcentral gyri) and right S2. We further show that this decoding is observed for familiar but not unfamiliar visual objects in S1. In addition, whole-brain searchlight decoding analyses revealed several areas in the parietal lobe that could mediate the observed context effects between vision and somatosensation. These results demonstrate that even the first cortical stages of somatosensory processing carry information about the category of visually presented familiar objects. © The Author 2013. Published by Oxford University Press.

  11. Safety comparison of four types of rabies vaccines in patients with WHO category II animal exposure

    PubMed Central

    Peng, Jun; Lu, Sha; Zhu, Zhenggang; Zhang, Man; Hu, Quan; Fang, Yuan

    2016-01-01

    Abstract To evaluate the safeties of 4 types of rabies vaccines for patients with WHO category II animal exposure, especially in different age groups. A total of 4000 patients with WHO category II animal exposure were randomly divided into 4 vaccine groups, and were respectively given with Vaccines A, B, C, and D. And subjects in each vaccine group were divided into 4 age groups (≤5, 5–18, 19–60, and ≥60-year-old groups). Then adverse events (including local and systemic ones) were recorded and compared. Consequently, except for Vaccine B, patients under the age of 5 in Groups A, C, and D suffered from more adverse reactions than those in other age groups. Furthermore, for the children aged less than 5 years, incidence of adverse events following administration of Vaccine B, with the dose of 0.5 mL and production of bioreactor systems, was significantly lower than Vaccines A and D. Our data showed that rabies vaccines with smaller doses and more advanced processing techniques are of relatively high safety for the patients, especially for the young children. PMID:27893654

  12. Health effects of risk-assessment categories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kramer, C.F.; Rybicka, K.; Knutson, A.

    Environmental and occupational health effects associated with exposures to various chemicals are a subject of increasing concern. One recently developed methodology for assessing the health impacts of various chemical compounds involves the classification of similar chemicals into risk-assessment categories (RACs). This report reviews documented human health effects for a broad range of pollutants, classified by RACs. It complements other studies that have estimated human health effects by RAC based on analysis and extrapolation of data from animal research.

  13. Safety of Iohexol Administration to Measure Glomerular Filtration Rate in Different Patient Populations: A 25-Year Experience.

    PubMed

    Gaspari, Flavio; Thakar, Surabhi; Carrara, Fabiola; Perna, Annalisa; Trillini, Matias; Aparicio, Maria Carolina; Diadei, Olimpia; Ferrari, Silvia; Cannata, Antonio; Stucchi, Nadia; Ruggenenti, Piero; Remuzzi, Giuseppe; Perico, Norberto

    2018-05-17

    In clinical research setting, accurate and precise measurement of glomerular filtration rate (GFR) is essential to overcome the limitations of GFR estimation with equations, which are often unreliable. In recent decades, a method for measuring GFR by plasma clearance of iohexol, a non-ionic radiocontrast agent, was developed. To evaluate the safety of the procedure, we aimed to review all immediate adverse reactions that could be related to iohexol administration in our group's 25 years worth of experience. We retrospectively reviewed all GFR investigations in 2,891 patients, between 1992 and 2016, as part of 37 clinical trials coordinated by our group. Subjects with disparate renal diseases, kidney transplant recipients, and living donors - all with different renal function categories - were included in the surveyed clinical trials. During 15,147 GFR measurements, only one treatment-related event of moderate intensity was identified. Flushing, urticaria, and itching were observed in a diabetic patient a few minutes after iohexol administration during the first GFR measurement. The event recovered without sequelae after intravenous injection of methylprednisolone sodium succinate. The patient was not hospitalized and the event was categorized as non-serious. Eight additional non-serious events observed closely following iohexol injection were considered as not related to treatment. Thus, independent of disease conditions and GFR categories, the overall rate of treatment-related events was 0.0066%. Iohexol administration for GFR measurement is a safe procedure, even in repeated investigations in the same subject, that should be adopted in clinical research and, when needed, also in clinical practice. © 2018 S. Karger AG, Basel.

  14. Quit Intentions Moderate Subjective and Physiological Responses to Acute Nicotine Replacement Therapy Administration in Dependent Smokers.

    PubMed

    Schlagintweit, Hera E; Campbell, Niamh K; Barrett, Sean P

    2017-08-01

    This study assessed the impact of expectancy and administration components of acute nicotine inhaler use on craving, heart rate, and smoking behavior in smokers with varying intentions to quit. 47 dependent smokers that differed in self-reported intention to quit (no intention to quit during the next month N = 26 vs. intention to initiate a quit attempt within 2 weeks N = 21) were randomly administered a 4 mg nicotine or nicotine-free inhaler across two sessions. Instructions regarding the inhaler's nicotine content (expect nicotine vs. expect nicotine-free; nicotine expectancy) and flavor (mint vs. citrus) varied across sessions. Craving and heart rate were assessed before and after inhaler administration (two-second inhalations every 10 seconds over 20 minutes). Next, participants were offered an opportunity to self-administer puffs of their preferred tobacco brand during an hour-long progressive ratio task. Across participants, nicotine expectancy independently reduced withdrawal related craving (p = .018), but no comparable effects of nicotine administration were evident. In quitting motivated smokers, nicotine expectancy and administration interacted to reduce intention to smoke (p = .040), while nicotine expectancy (p = .047) and administration (p = .025) independently reduced intention to smoke in quitting unmotivated smokers. Blunted heart rate reactivity to nicotine administration was observed in quitting motivated relative to unmotivated smokers (p = .042); however, neither expectancy nor administration impacted smoking behavior in either group (p values > .25). Findings indicate that participant quitting intentions moderate acute nicotine replacement therapy responses. In quitting motivated smokers, a combination of pharmacological and psychological factors may be necessary for nicotine replacement therapy to impact craving. Findings from this study demonstrate that motivations to quit smoking moderate subjective and physiological responses to acute

  15. Stakeholders analysis on criteria for protected areas management categories in Peninsular Malaysia

    NASA Astrophysics Data System (ADS)

    Hashim, Z.; Abdullah, S. A.; Nor, S. Md.

    2017-10-01

    The establishment of protected areas has always been associated with a strategy to conserve biodiversity. A well-managed protected areas not only protect the ecosystem and threatened species but also provides benefits to the public. These indeed require sound management practices through the application of protected areas management categories which can be is seen as tools for planning, establishment and administration of protected areas as well as to regulate the activities in the protected areas. However, in Peninsular Malaysia the implementation of the protected areas management categories was carried out based on the ‘ad-hoc’ basis without realising the important of the criteria based on the local values. Thus, an investigation has been sought to establish the criteria used in application to the protected areas management categories in Peninsular Malaysia. The outcomes revealed the significant of social, environment and economic criteria in establishing the protected area management categories in Peninsular Malaysia.

  16. Category vs. Object Knowledge in Category-Based Induction

    ERIC Educational Resources Information Center

    Murphy, Gregory L.; Ross, Brian H.

    2010-01-01

    In one form of category-based induction, people make predictions about unknown properties of objects. There is a tension between predictions made based on the object's specific features (e.g., objects above a certain size tend not to fly) and those made by reference to category-level knowledge (e.g., birds fly). Seven experiments with artificial…

  17. Mirror Asymmetry of Category and Letter Fluency in Traumatic Brain Injury and Alzheimer's Patients

    ERIC Educational Resources Information Center

    Capitani, Erminio; Rosci, Chiara; Saetti, Maria Cristina; Laiacona, Marcella

    2009-01-01

    In this study we contrasted the Category fluency and Letter fluency performance of 198 normal subjects, 57 Alzheimer's patients and 57 patients affected by traumatic brain injury (TBI). The aim was to check whether, besides the prevalence of Category fluency deficit often reported among Alzheimer's patients, the TBI group presented the opposite…

  18. Discontinuous categories affect information-integration but not rule-based category learning.

    PubMed

    Maddox, W Todd; Filoteo, J Vincent; Lauritzen, J Scott; Connally, Emily; Hejl, Kelli D

    2005-07-01

    Three experiments were conducted that provide a direct examination of within-category discontinuity manipulations on the implicit, procedural-based learning and the explicit, hypothesis-testing systems proposed in F. G. Ashby, L. A. Alfonso-Reese, A. U. Turken, and E. M. Waldron's (1998) competition between verbal and implicit systems model. Discontinuous categories adversely affected information-integration but not rule-based category learning. Increasing the magnitude of the discontinuity did not lead to a significant decline in performance. The distance to the bound provides a reasonable description of the generalization profile associated with the hypothesis-testing system, whereas the distance to the bound plus the distance to the trained response region provides a reasonable description of the generalization profile associated with the procedural-based learning system. These results suggest that within-category discontinuity differentially impacts information-integration but not rule-based category learning and provides information regarding the detailed processing characteristics of each category learning system. ((c) 2005 APA, all rights reserved).

  19. 12 CFR 621.10 - Monitoring of performance categories and other property owned.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Monitoring of performance categories and other property owned. 621.10 Section 621.10 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Loan Performance and Valuation Assessment § 621.10 Monitoring of...

  20. Measurement of habituation to noise using the method of continuous judgment by category

    NASA Astrophysics Data System (ADS)

    Namba, S.; Kuwano, S.

    1988-12-01

    Using "the method of continuous judgment by category", we examined the noisiness of sounds from public loudspeakers, and habituation to them. Subjects judged the noisiness of the sound at any moment of their choice by touching one of seven numbered keys on a computer keyboard, each corresponding to a noisiness category. At the same time, the subjects were required to complete a task as carefully and rapidly as possible. The duration of "no response" to sounds was an index of habituation. Both personality factors and physical factors were analyzed. It was found that the duration of "no response" is a good index to habituation to noise, and that there were wide differences in the "no response" time of different subjects. The reactions of individual subjects in sessions 1 and 2 and the questionnaire survey were, however, consistent. This suggests that there is a group that is relatively sensitive to noise and a group that is less sensitive to noise. It was also found that subjects had difficulty in becoming accustomed to intense noise.

  1. Combining features from ERP components in single-trial EEG for discriminating four-category visual objects.

    PubMed

    Wang, Changming; Xiong, Shi; Hu, Xiaoping; Yao, Li; Zhang, Jiacai

    2012-10-01

    Categorization of images containing visual objects can be successfully recognized using single-trial electroencephalograph (EEG) measured when subjects view images. Previous studies have shown that task-related information contained in event-related potential (ERP) components could discriminate two or three categories of object images. In this study, we investigated whether four categories of objects (human faces, buildings, cats and cars) could be mutually discriminated using single-trial EEG data. Here, the EEG waveforms acquired while subjects were viewing four categories of object images were segmented into several ERP components (P1, N1, P2a and P2b), and then Fisher linear discriminant analysis (Fisher-LDA) was used to classify EEG features extracted from ERP components. Firstly, we compared the classification results using features from single ERP components, and identified that the N1 component achieved the highest classification accuracies. Secondly, we discriminated four categories of objects using combining features from multiple ERP components, and showed that combination of ERP components improved four-category classification accuracies by utilizing the complementarity of discriminative information in ERP components. These findings confirmed that four categories of object images could be discriminated with single-trial EEG and could direct us to select effective EEG features for classifying visual objects.

  2. Incidental Auditory Category Learning

    PubMed Central

    Gabay, Yafit; Dick, Frederic K.; Zevin, Jason D.; Holt, Lori L.

    2015-01-01

    Very little is known about how auditory categories are learned incidentally, without instructions to search for category-diagnostic dimensions, overt category decisions, or experimenter-provided feedback. This is an important gap because learning in the natural environment does not arise from explicit feedback and there is evidence that the learning systems engaged by traditional tasks are distinct from those recruited by incidental category learning. We examined incidental auditory category learning with a novel paradigm, the Systematic Multimodal Associations Reaction Time (SMART) task, in which participants rapidly detect and report the appearance of a visual target in one of four possible screen locations. Although the overt task is rapid visual detection, a brief sequence of sounds precedes each visual target. These sounds are drawn from one of four distinct sound categories that predict the location of the upcoming visual target. These many-to-one auditory-to-visuomotor correspondences support incidental auditory category learning. Participants incidentally learn categories of complex acoustic exemplars and generalize this learning to novel exemplars and tasks. Further, learning is facilitated when category exemplar variability is more tightly coupled to the visuomotor associations than when the same stimulus variability is experienced across trials. We relate these findings to phonetic category learning. PMID:26010588

  3. Category-length and category-strength effects using images of scenes.

    PubMed

    Baumann, Oliver; Vromen, Joyce M G; Boddy, Adam C; Crawshaw, Eloise; Humphreys, Michael S

    2018-06-21

    Global matching models have provided an important theoretical framework for recognition memory. Key predictions of this class of models are that (1) increasing the number of occurrences in a study list of some items affects the performance on other items (list-strength effect) and that (2) adding new items results in a deterioration of performance on the other items (list-length effect). Experimental confirmation of these predictions has been difficult, and the results have been inconsistent. A review of the existing literature, however, suggests that robust length and strength effects do occur when sufficiently similar hard-to-label items are used. In an effort to investigate this further, we had participants study lists containing one or more members of visual scene categories (bathrooms, beaches, etc.). Experiments 1 and 2 replicated and extended previous findings showing that the study of additional category members decreased accuracy, providing confirmation of the category-length effect. Experiment 3 showed that repeating some category members decreased the accuracy of nonrepeated members, providing evidence for a category-strength effect. Experiment 4 eliminated a potential challenge to these results. Taken together, these findings provide robust support for global matching models of recognition memory. The overall list lengths, the category sizes, and the number of repetitions used demonstrated that scene categories are well-suited to testing the fundamental assumptions of global matching models. These include (A) interference from memories for similar items and contexts, (B) nondestructive interference, and (C) that conjunctive information is made available through a matching operation.

  4. Clinical Parameters following Multiple Oral Dose Administration of a Standardized Andrographis paniculata Capsule in Healthy Thai Subjects.

    PubMed

    Suriyo, Tawit; Pholphana, Nanthanit; Ungtrakul, Teerapat; Rangkadilok, Nuchanart; Panomvana, Duangchit; Thiantanawat, Apinya; Pongpun, Wanwisa; Satayavivad, Jutamaad

    2017-06-01

    Andrographis paniculata has been widely used in Scandinavian and Asian counties for the treatment of the common cold, fever, and noninfectious diarrhea. The present study was carried out to investigate the physiological effects of short-term multiple dose administration of a standardized A. paniculata capsule used for treatment of the common cold and uncomplicated upper respiratory tract infections, including blood pressure, electrocardiogram, blood chemistry, hematological profiles, urinalysis, and blood coagulation in healthy Thai subjects. Twenty healthy subjects (10 males and 10 females) received 12 capsules per day orally of 4.2 g of a standardized A. paniculata crude powder (4 capsules of 1.4 g of A. paniculata , 3 times per day, 8 h intervals) for 3 consecutive days. The results showed that all of the measured clinical parameters were found to be within normal ranges for a healthy person. However, modulation of some parameters was observed after the third day of treatment, for example, inductions of white blood cells and absolute neutrophil count in the blood, a reduction of plasma alkaline phosphatase, and an induction of urine pH. A rapid and transient reduction in blood pressure was observed at 30 min after capsule administration, resulting in a significant reduction of mean systolic blood pressure. There were no serious adverse events observed in the subjects during the treatment period. In conclusion, this study suggests that multiple oral dosing of A. paniculata at the normal therapeutic dose for the common cold and uncomplicated upper respiratory tract infections modulates various clinical parameters within normal ranges for a healthy person. Georg Thieme Verlag KG Stuttgart · New York.

  5. 77 FR 33269 - Designation of Product Categories for Federal Procurement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... under such a contract.'' Thus, Federal contractors, as well as Federal agencies, are expressly subject... generally to procure such a product composed of the highest percentage of recovered materials content... those product categories that contain the highest biobased content. In addition, as the program matures...

  6. The Time Course of Recovery for Grammatical Category Information During Lexical Processing for Syntactic Construction

    ERIC Educational Resources Information Center

    Pechmann, Thomas; Garrett, Merrill; Zerbst, Dieter

    2004-01-01

    In the experiments outlined in this article, the authors investigate lexical access processes in language production. In their earlier work, T. Pechmann and D. Zerbst (2002) reported evidence for grammatical category constraints in a picture-word interference task. Although grammatical category information was not activated when subjects produced…

  7. Rank 4 Premodular Categories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bruillard, Paul J.; Galindo, Cesar; Ng, Siu Hung

    2016-09-01

    We consider the classification problem for rank 4 premodular categories. We uncover a formula for the 2nd Frobenius-Schur indicator of a premodular category is determined and the classification of rank 4 premodular categories (up to Grothendieck equivalence) is completed. In the appendix we show rank finiteness for premodular categories.

  8. Ideals and Category Typicality

    ERIC Educational Resources Information Center

    Kim, ShinWoo; Murphy, Gregory L.

    2011-01-01

    Barsalou (1985) argued that exemplars that serve category goals become more typical category members. Although this claim has received support, we investigated (a) whether categories have a single ideal, as negatively valenced categories (e.g., cigarette) often have conflicting goals, and (b) whether ideal items are in fact typical, as they often…

  9. 41 CFR 109-1.5108-5 - Administratively controlled items.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...-INTRODUCTION 1.51-Personal Property Management Standards and Practices § 109-1.5108-5 Administratively controlled items. No formal property management records are required to be maintained for this category of... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Administratively...

  10. 41 CFR 109-1.5108-5 - Administratively controlled items.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...-INTRODUCTION 1.51-Personal Property Management Standards and Practices § 109-1.5108-5 Administratively controlled items. No formal property management records are required to be maintained for this category of... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Administratively...

  11. 41 CFR 109-1.5108-5 - Administratively controlled items.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-INTRODUCTION 1.51-Personal Property Management Standards and Practices § 109-1.5108-5 Administratively controlled items. No formal property management records are required to be maintained for this category of... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Administratively...

  12. 41 CFR 109-1.5108-5 - Administratively controlled items.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...-INTRODUCTION 1.51-Personal Property Management Standards and Practices § 109-1.5108-5 Administratively controlled items. No formal property management records are required to be maintained for this category of... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Administratively...

  13. 40 CFR 1042.310 - Engine selection for Category 1 and Category 2 engines.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Category 2 engines. (a) Determine minimum sample sizes as follows: (1) For Category 1 engines, the minimum sample size is one engine or one percent of the projected U.S.-directed production volume for all your Category 1 engine families, whichever is greater. (2) For Category 2 engines, the minimum sample size is...

  14. Supporting drivers in forming correct expectations about transitions between rural road categories.

    PubMed

    Stelling-Konczak, Agnieszka; Aarts, Letty; Duivenvoorden, Kirsten; Goldenbeld, Charles

    2011-01-01

    In order to support drivers in forming the right expectations on the road, road categories are being made recognisable and predictable in the Netherlands. The present study investigated which of the selected road layouts can make rural road categories most recognisable for road users, especially in transitions from one road category to another. A second objective was to study whether explicit information could contribute to a better recognisability of transitions. The experiment was performed with a series of photographs showing sections of two road categories with an intersection in between. The road layout of road categories varied in markings and separation of driving direction (within-subjects factor). Informed and non-informed participants (between-subjects factor) had to indicate their expectations regarding speed limit and access restriction of each road section, before and after a transition. The results show that for transitions between distributor and through roads, the physicality of separation of driving direction is a better distinctive characteristic than the currently used edge marking. The green centre marking on through roads also enhances recognisability, but only with additional information. As far as transitions between distributor and access roads are concerned, the results demonstrate that this type of transitions is better recognised when no markings on access roads are present. Physical separation of driving directions on distributor roads also improves recognisability, although this layout is associated with higher speed limits. Providing explicit information has in general a positive effect on the reconisability of transitions. Implications are discussed in the light of potential safety effects. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. Visual Images of Subjective Perception of Time in a Literary Text

    ERIC Educational Resources Information Center

    Nesterik, Ella V.; Issina, Gaukhar I.; Pecherskikh, Taliya F.; Belikova, Oxana V.

    2016-01-01

    The article is devoted to the subjective perception of time, or psychological time, as a text category and a literary image. It focuses on the visual images that are characteristic of different types of literary time--accelerated, decelerated and frozen (vanished). The research is based on the assumption that the category of subjective perception…

  16. Valuation, Categories and Attributes

    PubMed Central

    Galperin, Inna; Sorenson, Olav

    2014-01-01

    Existing research on categories has only examined indirectly the value associated with being a member of a category relative to the value of the set of attributes that determine membership in that category. This study uses survey data to analyze consumers' preferences for the "organic” label versus for the attributes underlying that label. We found that consumers generally preferred products with the category label to those with the attributes required for the organic label but without the label. We also found that the value accorded to the organic label increased with the number of attributes that an individual associated with the category. Category membership nevertheless still had greater value than even that of the sum of the attributes associated with it. PMID:25111831

  17. Drug utilization and teratogenicity risk categories during pregnancy.

    PubMed

    Basgül, Alin; Akici, Ahmet; Uzuner, Arzu; Kalaça, Sibel; Kavak, Zehra N; Tural, Alper; Oktay, Sule

    2007-01-01

    A limited number of studies have investigated in detail the use of drugs during pregnancy. Researchers in the present study investigated the details of drug utilization in pregnant women during the month before pregnancy, at the time that they became aware of the pregnancy, and during the first trimester. Face-to-face interviews were conducted with 359 pregnant women who were admitted to the fetal medicine unit at a university hospital for diagnosis and follow-up. A questionnaire was used to document sociodemographic characteristics and details of drug use. Drugs were categorized according to the US Food and Drug Administration fetal risk classification. Mean maternal age was 29.9+/-5.1 y, and mean gestational age was 19.6+/-9.5 wk. Many of the pregnant women studied (46.6%) were university graduates, and most (61.9%) had a relatively high annual income. Mean gestational age when participants first learned of their pregnancy was 39.8+/-16.4 d. One hundred seventeen participants (32.6%) used drugs during the month before conception, 54 (15%) at the time when they learned of their pregnancy, 180 (50.1%) at the time of the interview, and 289 (80.5%) during the first trimester. The percentages of drugs in categories D and X used by these subjects were 14%, 13.5%, 2.9%, and 5.9%, respectively. Most of the drugs were hormones. The total rate of drug utilization was not high before and during the first trimester of pregnancy. A considerable number of women were using drugs from the D and X categories; however, these numbers decreased significantly when women learned of their pregnancies. Intake of folic acid, vitamins, and iron was very low during the preconception period and was not high enough during the first trimester; this suggests that particular attention should be paid to the use of beneficial "safe" drugs during the preconception and early pregnancy periods.

  18. Fourier power, subjective distance, and object categories all provide plausible models of BOLD responses in scene-selective visual areas

    PubMed Central

    Lescroart, Mark D.; Stansbury, Dustin E.; Gallant, Jack L.

    2015-01-01

    Perception of natural visual scenes activates several functional areas in the human brain, including the Parahippocampal Place Area (PPA), Retrosplenial Complex (RSC), and the Occipital Place Area (OPA). It is currently unclear what specific scene-related features are represented in these areas. Previous studies have suggested that PPA, RSC, and/or OPA might represent at least three qualitatively different classes of features: (1) 2D features related to Fourier power; (2) 3D spatial features such as the distance to objects in a scene; or (3) abstract features such as the categories of objects in a scene. To determine which of these hypotheses best describes the visual representation in scene-selective areas, we applied voxel-wise modeling (VM) to BOLD fMRI responses elicited by a set of 1386 images of natural scenes. VM provides an efficient method for testing competing hypotheses by comparing predictions of brain activity based on encoding models that instantiate each hypothesis. Here we evaluated three different encoding models that instantiate each of the three hypotheses listed above. We used linear regression to fit each encoding model to the fMRI data recorded from each voxel, and we evaluated each fit model by estimating the amount of variance it predicted in a withheld portion of the data set. We found that voxel-wise models based on Fourier power or the subjective distance to objects in each scene predicted much of the variance predicted by a model based on object categories. Furthermore, the response variance explained by these three models is largely shared, and the individual models explain little unique variance in responses. Based on an evaluation of previous studies and the data we present here, we conclude that there is currently no good basis to favor any one of the three alternative hypotheses about visual representation in scene-selective areas. We offer suggestions for further studies that may help resolve this issue. PMID:26594164

  19. Is better beautiful or is beautiful better? Exploring the relationship between beauty and category structure.

    PubMed

    Sanders, Megan; Davis, Tyler; Love, Bradley C

    2013-06-01

    We evaluate two competing accounts of the relationship between beauty and category structure. According to the similarity-based view, beauty arises from category structure such that central items are favored due to their increased fluency. In contrast, the theory-based view holds that people's theories of beauty shape their perceptions of categories. In the present study, subjects learned to categorize abstract paintings into meaningfully labeled categories and rated the paintings' beauty, value, and typicality. Inconsistent with the similarity-based view, beauty ratings were highly correlated across conditions despite differences in fluency and assigned category structure. Consistent with the theory-based view, beautiful paintings were treated as central members for categories expected to contain beautiful paintings (e.g., art museum pieces), but not in others (e.g., student show pieces). These results suggest that the beauty of complex, real-world stimuli is not determined by fluency within category structure but, instead, interacts with people's prior knowledge to structure categories.

  20. Identity, gender, and subjective well-being.

    PubMed

    Chang, Wen-Chun

    2011-01-01

    Using the self-reported level of happiness as a measure of subjective well-being, this study examines the relationship between gender identity and subjective well-being with data from Taiwan. The findings suggest that an individual's perceptions about the ideals of women's gender roles in the labor market, the family, and politics are strongly related to his or her assigned social category, the prescriptions and characteristics associated with the social category, and the actions taken to match the ideals of gender identity. Consistent with Akerlof and Kranton's (2000) identity model, it is also found that an individual's gains or losses in gender identity lead to increases or decreases in the level of happiness.

  1. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  2. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  3. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  4. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  5. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  6. Functional connectivity constrains the category-related organization of human ventral occipitotemporal cortex

    PubMed Central

    Stevens, W. Dale; Tessler, Michael Henry; Peng, Cynthia S.; Martin, Alex

    2015-01-01

    One of the most robust and oft-replicated findings in cognitive neuroscience is that several spatially distinct, functionally dissociable ventral occipitotemporal cortex (VOTC) regions respond preferentially to different categories of concrete entities. However, the determinants of this category-related organization remain to be fully determined. One recent proposal is that privileged connectivity of these VOTC regions with other regions that store and/or process category-relevant properties may be a major contributing factor. To test this hypothesis, we used a multi-category functional MRI localizer to individually define category-related brain regions of interest (ROIs) in a large group of subjects (n=33). We then used these ROIs in resting-state functional connectivity MRI analyses to explore spontaneous functional connectivity among these regions. We demonstrate that during rest, distinct category-preferential VOTC regions show differentially stronger functional connectivity with other regions that have congruent category-preference, as defined by the functional localizer. Importantly, a ‘tool’-preferential region in the left medial fusiform gyrus showed differentially stronger functional connectivity with other left lateralized cortical regions associated with perceiving and knowing about common tools – posterior middle temporal gyrus (involved in perception of non-biological motion), lateral parietal cortex (critical for reaching, grasping, manipulating), and ventral premotor cortex (involved in storing/executing motor programs) – relative to other category-related regions in VOTC of both the right and left hemisphere. Our findings support the claim that privileged connectivity with other cortical regions that store and/or process category-relevant properties constrains the category-related organization of VOTC. PMID:25704493

  7. The impact of category structure and training methodology on learning and generalizing within-category representations.

    PubMed

    Ell, Shawn W; Smith, David B; Peralta, Gabriela; Hélie, Sébastien

    2017-08-01

    When interacting with categories, representations focused on within-category relationships are often learned, but the conditions promoting within-category representations and their generalizability are unclear. We report the results of three experiments investigating the impact of category structure and training methodology on the learning and generalization of within-category representations (i.e., correlational structure). Participants were trained on either rule-based or information-integration structures using classification (Is the stimulus a member of Category A or Category B?), concept (e.g., Is the stimulus a member of Category A, Yes or No?), or inference (infer the missing component of the stimulus from a given category) and then tested on either an inference task (Experiments 1 and 2) or a classification task (Experiment 3). For the information-integration structure, within-category representations were consistently learned, could be generalized to novel stimuli, and could be generalized to support inference at test. For the rule-based structure, extended inference training resulted in generalization to novel stimuli (Experiment 2) and inference training resulted in generalization to classification (Experiment 3). These data help to clarify the conditions under which within-category representations can be learned. Moreover, these results make an important contribution in highlighting the impact of category structure and training methodology on the generalization of categorical knowledge.

  8. Multivariate Pattern Analysis Reveals Category-Related Organization of Semantic Representations in Anterior Temporal Cortex.

    PubMed

    Malone, Patrick S; Glezer, Laurie S; Kim, Judy; Jiang, Xiong; Riesenhuber, Maximilian

    2016-09-28

    The neural substrates of semantic representation have been the subject of much controversy. The study of semantic representations is complicated by difficulty in disentangling perceptual and semantic influences on neural activity, as well as in identifying stimulus-driven, "bottom-up" semantic selectivity unconfounded by top-down task-related modulations. To address these challenges, we trained human subjects to associate pseudowords (TPWs) with various animal and tool categories. To decode semantic representations of these TPWs, we used multivariate pattern classification of fMRI data acquired while subjects performed a semantic oddball detection task. Crucially, the classifier was trained and tested on disjoint sets of TPWs, so that the classifier had to use the semantic information from the training set to correctly classify the test set. Animal and tool TPWs were successfully decoded based on fMRI activity in spatially distinct subregions of the left medial anterior temporal lobe (LATL). In addition, tools (but not animals) were successfully decoded from activity in the left inferior parietal lobule. The tool-selective LATL subregion showed greater functional connectivity with left inferior parietal lobule and ventral premotor cortex, indicating that each LATL subregion exhibits distinct patterns of connectivity. Our findings demonstrate category-selective organization of semantic representations in LATL into spatially distinct subregions, continuing the lateral-medial segregation of activation in posterior temporal cortex previously observed in response to images of animals and tools, respectively. Together, our results provide evidence for segregation of processing hierarchies for different classes of objects and the existence of multiple, category-specific semantic networks in the brain. The location and specificity of semantic representations in the brain are still widely debated. We trained human participants to associate specific pseudowords with various

  9. Children's Category-Based Inferences Affect Classification

    ERIC Educational Resources Information Center

    Ross, Brian H.; Gelman, Susan A.; Rosengren, Karl S.

    2005-01-01

    Children learn many new categories and make inferences about these categories. Much work has examined how children make inferences on the basis of category knowledge. However, inferences may also affect what is learned about a category. Four experiments examine whether category-based inferences during category learning influence category knowledge…

  10. Effect of co-administration of fluoxetine and amantadine on immunoendocrine parameters in rats subjected to a forced swimming test.

    PubMed

    Rogóz, Zofia; Kubera, Marta; Rogóz, Katarzyna; Basta-Kaim, Agnieszka; Budziszewska, Bogusława

    2009-01-01

    Considerable attention has been paid to a possible role of immunological dysregulation in the pathogenesis of depression. It has been reported that combined administration of antidepressant drugs and the non-competitive NMDA receptor antagonist amantadine reduces immobility time in the forced swimming test (FST). Moreover, preliminary clinical data show that such a combination of drugs has a beneficial effect on treatment-resistant depressed patients. Since immune activation and a pro-inflammatory response are clearly evident in treatment-resistant depression, the aim of the present study was to examine the effect of a combination of the antidepressant fluoxetine and amantadine on immunoendocrine parameters in rats subjected to the forced swimming test. The obtained results revealed synergistic antidepressant effects of the combined administration of fluoxetine (10 mg/kg) and amantadine (10 mg/kg) - drugs otherwise ineffective when given separately in the above doses. Antidepressant activity was accompanied with a significant decrease in the capacity of splenocytes to proliferate in response to concanavalin A. Moerover, fluoxetine and the combination of amantadine and fluoxetine reduced relative spleen weight in rats subjected to the FST, compared to rats treated with the vehicle. The combination of amantadine and fluoxetine enhanced the production of the negative immunoregulator interleukin-10 (but not interferon-gamma) in rats subjected to the FST. The exposure to the FST produced an increase in plasma corticosterone levels, which was significantly attenuated by pretreatment with fluoxetine and amantadine. In summary, the antidepressive efficacy of a combination of fluoxetine and amantadine given in suboptimal doses may be related to the negative immunoendocrine effects of these drugs.

  11. Encoding tasks dissociate the effects of divided attention on category-cued recall and category-exemplar generation.

    PubMed

    Parker, Andrew; Dagnall, Neil; Munley, Gary

    2012-01-01

    The combined effects of encoding tasks and divided attention upon category-exemplar generation and category-cued recall were examined. Participants were presented with pairs of words each comprising a category name and potential example of that category. They were then asked to indicate either (i) their liking for both of the words or (ii) if the exemplar was a member of the category. It was found that divided attention reduced performance on the category-cued recall task under both encoding conditions. However, performance on the category-exemplar generation task remained invariant across the attention manipulation following the category judgment task. This provides further evidence that the processes underlying performance on conceptual explicit and implicit memory tasks can be dissociated, and that the intentional formation of category-exemplar associations attenuates the effects of divided attention on category-exemplar generation.

  12. Classification of occupational activity categories using accelerometry: NHANES 2003-2004.

    PubMed

    Steeves, Jeremy A; Tudor-Locke, Catrine; Murphy, Rachel A; King, George A; Fitzhugh, Eugene C; Harris, Tamara B

    2015-06-30

    An individual's occupational activity (OA) may contribute significantly to daily physical activity (PA) and sedentary behavior (SB). However, there is little consensus about which occupational categories involve high OA or low OA, and the majority of categories are unclassifiable with current methods. The purpose of this study was to present population estimates of accelerometer-derived PA and SB variables for adults (n = 1112, 20-60 years) working the 40 occupational categories collected during the 2003-2004 National Health and Nutrition Examination Survey (NHANES). ActiGraph accelerometer-derived total activity counts/day (TAC), activity counts/minute, and proportion of wear time spent in moderate-to-vigorous PA [MVPA], lifestyle, and light PA organized by occupational category were ranked in ascending order and SB was ranked in descending order. Summing the ranks of the six accelerometer-derived variables generated a summary score for each occupational category, which was re-ranked in ascending order. Higher rankings indicated higher levels of OA, lower rankings indicated lower levels of OA. Tertiles of the summary score were used to establish three mutually exclusive accelerometer-determined OA groupings: high OA, intermediate OA, and low OA. According to their summary score, 'farm and nursery workers' were classified as high OA and 'secretaries, stenographers, and typists' were classified as low OA. Consistent with previous research, some low OA occupational categories (e.g., 'engineers, architects, and scientists', 'technicians and related support occupations', 'management related occupations', 'executives, administrators, and managers', 'protective services', and 'writers, artists, entertainers, and athletes') associated with higher education and income had relatively greater amounts of MVPA compared to other low OA occupational categories, likely due to the greater percentage of men in those occupations and/or the influence of higher levels of leisure

  13. Human subjects research handbook: Protecting human research subjects. Second edition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-01-30

    This handbook serves as a guide to understanding and implementing the Federal regulations and US DOE Orders established to protect human research subjects. Material in this handbook is directed towards new and continuing institutional review board (IRB) members, researchers, institutional administrators, DOE officials, and others who may be involved or interested in human subjects research. It offers comprehensive overview of the various requirements, procedures, and issues relating to human subject research today.

  14. Category and stereotype activation revisited.

    PubMed

    Akrami, Nazar; Ekehammar, Bo; Araya, Tadesse

    2006-12-01

    In Study 1 (N= 230), we found that the participants' explicit prejudice was not related to their knowledge of cultural stereotypes of immigrants in Sweden, and that they associated the social category immigrants with the same national/ethnic categories. In Study 2 (N= 88), employing the category and stereotype words obtained in Study 1 as primes, we examined whether participants with varying degrees of explicit prejudice differed in their automatic stereotyping and implicit prejudice when primed with category or stereotypical words. In accord with our hypothesis, and contrary to previous findings, the results showed that people's explicit prejudice did not affect their automatic stereotyping and implicit prejudice, neither in the category nor stereotype priming condition. Study 3 (N= 62), employing category priming using facial photographs of Swedes and immigrants as primes, showed that participants' implicit prejudice was not moderated by their explicit prejudice. The outcome is discussed in relation to the distinction between category and stereotype priming and in terms of the associative strength between a social category and its related stereotypes.

  15. Effect of intraperitoneal selenium administration on liver glycogen levels in rats subjected to acute forced swimming.

    PubMed

    Akil, Mustafa; Bicer, Mursel; Kilic, Mehmet; Avunduk, Mustafa Cihat; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim

    2011-03-01

    There are a few of studies examining how selenium, which is known to reduce oxidative damage in exercise, influences glucose metabolism and exhaustion in physical activity. The present study aims to examine how selenium administration affects liver glycogen levels in rats subjected to acute swimming exercise. The study included 32 Sprague-Dawley type male rats, which were equally allocated to four groups: Group 1, general control; Group 2; selenium-supplemented control (6 mg/kg/day sodium selenite); Group 3, swimming control; Group 4, selenium-supplemented swimming (6 mg/kg/day sodium selenite). Liver tissue samples collected from the animals at the end of the study were fixed in 95% ethyl alcohol. From the tissue samples buried into paraffin, 5-µm cross-sections were obtained using a microtome, put on a microscope slide, and stained with PAS. Stained preparations were assessed using a Nikon Eclipse E400 light microscope. All images obtained with the light microscope were transferred to a PC and evaluated using Clemex PE 3.5 image analysis software. The highest liver glycogen levels were found in groups 1 and 2 (p < 0.05). The levels in group 4 were lower than those in groups 1 and 2 but higher than the levels in group 3 (p < 0.05). The lowest liver glycogen levels were obtained in group 3 (p < 0.05). Results of the study indicate that liver glycogen levels that decrease in acute swimming exercise can be restored by selenium administration. It can be argued that physiological doses of selenium administration can contribute to performance.

  16. A developmental examination of the conceptual structure of animal, artifact, and human social categories across two cultural contexts

    PubMed Central

    Rhodes, Marjorie; Gelman, Susan A.

    2009-01-01

    Previous research indicates that the ontological status that adults attribute to categories varies systematically by domain. For example, adults view distinctions between different animal species as natural and objective, but view distinctions between different kinds of furniture as more conventionalized and subjective. The present work (N = 435; ages 5-18) examined the effects of domain, age, and cultural context on beliefs about the naturalness vs. conventionality of categories. Results demonstrate that young children, like adults, view animal categories as natural kinds, but artifact categories as more conventionalized. For human social categories (gender and race), beliefs about naturalness and conventionality were predicted by interactions between cultural context and age. Implications for the origins of social categories and theories of conceptual development will be discussed. PMID:19524886

  17. Prevalence of Metabolic Syndrome and Its Components among Japanese Workers by Clustered Business Category.

    PubMed

    Hidaka, Tomoo; Hayakawa, Takehito; Kakamu, Takeyasu; Kumagai, Tomohiro; Hiruta, Yuhei; Hata, Junko; Tsuji, Masayoshi; Fukushima, Tetsuhito

    2016-01-01

    The present study was a cross-sectional study conducted to reveal the prevalence of metabolic syndrome and its components and describe the features of such prevalence among Japanese workers by clustered business category using big data. The data of approximately 120,000 workers were obtained from a national representative insurance organization, and the study analyzed the health checkup and questionnaire results according to the field of business of each subject. Abnormalities found during the checkups such as excessive waist circumference, hypertension or glucose intolerance, and metabolic syndrome, were recorded. All subjects were classified by business field into 18 categories based on The North American Industry Classification System. Based on the criteria of the Japanese Committee for the Diagnostic Criteria of Metabolic Syndrome, the standardized prevalence ratio (SPR) of metabolic syndrome and its components by business category was calculated, and the 95% confidence interval of the SPR was computed. Hierarchical cluster analysis was then performed based on the SPR of metabolic syndrome components, and the 18 business categories were classified into three clusters for both males and females. The following business categories were at significantly high risk of metabolic syndrome: among males, Construction, Transportation, Professional Services, and Cooperative Association; and among females, Health Care and Cooperative Association. The results of the cluster analysis indicated one cluster for each gender with a higher prevalence of metabolic syndrome components; among males, a cluster consisting of Manufacturing, Transportation, Finance, and Cooperative Association, and among females, a cluster consisting of Mining, Transportation, Finance, Accommodation, and Cooperative Association. These findings reveal that, when providing health guidance and support regarding metabolic syndrome, consideration must be given to its components and the variety of its

  18. Prevalence of Metabolic Syndrome and Its Components among Japanese Workers by Clustered Business Category

    PubMed Central

    Hidaka, Tomoo; Hayakawa, Takehito; Kakamu, Takeyasu; Kumagai, Tomohiro; Hiruta, Yuhei; Hata, Junko; Tsuji, Masayoshi; Fukushima, Tetsuhito

    2016-01-01

    The present study was a cross-sectional study conducted to reveal the prevalence of metabolic syndrome and its components and describe the features of such prevalence among Japanese workers by clustered business category using big data. The data of approximately 120,000 workers were obtained from a national representative insurance organization, and the study analyzed the health checkup and questionnaire results according to the field of business of each subject. Abnormalities found during the checkups such as excessive waist circumference, hypertension or glucose intolerance, and metabolic syndrome, were recorded. All subjects were classified by business field into 18 categories based on The North American Industry Classification System. Based on the criteria of the Japanese Committee for the Diagnostic Criteria of Metabolic Syndrome, the standardized prevalence ratio (SPR) of metabolic syndrome and its components by business category was calculated, and the 95% confidence interval of the SPR was computed. Hierarchical cluster analysis was then performed based on the SPR of metabolic syndrome components, and the 18 business categories were classified into three clusters for both males and females. The following business categories were at significantly high risk of metabolic syndrome: among males, Construction, Transportation, Professional Services, and Cooperative Association; and among females, Health Care and Cooperative Association. The results of the cluster analysis indicated one cluster for each gender with a higher prevalence of metabolic syndrome components; among males, a cluster consisting of Manufacturing, Transportation, Finance, and Cooperative Association, and among females, a cluster consisting of Mining, Transportation, Finance, Accommodation, and Cooperative Association. These findings reveal that, when providing health guidance and support regarding metabolic syndrome, consideration must be given to its components and the variety of its

  19. Evaluating Maintenance Performance: Test Administrator's Manual and Test Subject's Instructions for Criterion Referenced Job Task Performance Tests for Electronic Maintenance. Final Report.

    ERIC Educational Resources Information Center

    Shriver, Edgar L.; And Others

    This document furnishes a complete copy of the Test Subject's Instructions and the Test Administrator's Handbook for a battery of criterion referenced Job Task Performance Tests (JTPT) for electronic maintenance. General information is provided on soldering, Radar Set AN/APN-147(v), Radar Set Special Equipment, Radar Set Bench Test Set-Up, and…

  20. 75 FR 34953 - Existence of Proposed Airworthiness Design Standards for Acceptance Under the Primary Category...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... the proposed airworthiness design standards for acceptance of the OHA, Inc., Models Cessna 172I, 172K... Airworthiness Design Standards for Acceptance Under the Primary Category Rule; Orlando Helicopter Airways (OHA), Inc., Models Cessna 172I, 172K, 172L, and 172M AGENCY: Federal Aviation Administration (FAA), DOT...

  1. 75 FR 47494 - Implementation Guidance for Physical Protection of Byproduct Material; Category 1 and Category 2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... for Physical Protection of Byproduct Material; Category 1 and Category 2 Quantities of Radioactive... on the draft implementation guidance for proposed 10 CFR part 37 Physical Protection of Byproduct... proposed 10 CFR part 37, Physical Protection of Byproduct Material, specifically Category 1 and Category 2...

  2. 7 CFR 760.1301 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Administration. 760.1301 Section 760.1301 Agriculture... Administration. (a) This subpart establishes, subject to the availability of funds, the terms and conditions... Administration, and Related Agencies Appropriations Act, 2010 (2010 Agriculture Appropriations Bill, Pub. L. 111...

  3. 30 CFR Appendix I to Subpart T of... - Standard Applicability by Category or Subcategory

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Subcategory I Appendix I to Subpart T of Part 57 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION... AND NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Pt. 57, Subpt. T, App. I Appendix I to Subpart T of Part 57—Standard Applicability by Category or Subcategory Subcategory I-A 57...

  4. 30 CFR Appendix I to Subpart T of... - Standard Applicability by Category or Subcategory

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Subcategory I Appendix I to Subpart T of Part 57 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION... AND NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Pt. 57, Subpt. T, App. I Appendix I to Subpart T of Part 57—Standard Applicability by Category or Subcategory Subcategory I-A 57...

  5. Treatment of category generation and retrieval in aphasia: Effect of typicality of category items.

    PubMed Central

    Kiran, Swathi; Sandberg, Chaleece; Sebastian, Rajani

    2011-01-01

    Purpose: Kiran and colleagues (Kiran, 2007, 2008; Kiran & Johnson, 2008; Kiran & Thompson, 2003) have previously suggested that training atypical examples within a semantic category is a more efficient treatment approach to facilitating generalization within the category than training typical examples. The present study extended our previous work examining the notion of semantic complexity within goal-derived (ad-hoc) categories in individuals with aphasia. Methods: Six individuals with fluent aphasia (range = 39-84 years) and varying degrees of naming deficits and semantic impairments were involved. Thirty typical and atypical items each from two categories were selected after an extensive stimulus norming task. Generative naming for the two categories was tested during baseline and treatment. Results: As predicted, training atypical examples in the category resulted in generalization to untrained typical examples in five out the five patient-treatment conditions. In contrast, training typical examples (which was in examined three conditions) produced mixed results. One patient showed generalization to untrained atypical examples, whereas two patients did not show generalization to untrained atypical examples. Conclusions: Results of the present study supplement our existing data on the effect of a semantically based treatment for lexical retrieval by manipulating the typicality of category exemplars. PMID:21173393

  6. Conceptual influences on category-based induction

    PubMed Central

    Gelman, Susan A.; Davidson, Natalie S.

    2013-01-01

    One important function of categories is to permit rich inductive inferences. Prior work shows that children use category labels to guide their inductive inferences. However, there are competing theories to explain this phenomenon, differing in the roles attributed to conceptual information versus perceptual similarity. Seven experiments with 4- to 5-year-old children and adults (N = 344) test these theories by teaching categories for which category membership and perceptual similarity are in conflict, and varying the conceptual basis of the novel categories. Results indicate that for non-natural kind categories that have little conceptual coherence, children make inferences based on perceptual similarity, whereas adults make inferences based on category membership. In contrast, for basic- and ontological-level categories that have a principled conceptual basis, children and adults alike make use of category membership more than perceptual similarity as the basis of their inferences. These findings provide evidence in favor of the role of conceptual information in preschoolers’ inferences, and further demonstrate that labeled categories are not all equivalent; they differ in their inductive potential. PMID:23517863

  7. Understanding Vulnerability: From Categories to Experiences of Young Congolese People in Uganda

    ERIC Educational Resources Information Center

    Clark, Christina R.

    2007-01-01

    This article problematises the "vulnerables" category that the United Nations High Commissioner for Refugees applies to groups of refugees. Drawing on 9 months' qualitative research with young Congolese refugees in Uganda, it presents research subjects' self-identification and lived realities that do not correspond to the homogenous,…

  8. Effect of long-term intraperitoneal zinc administration on liver glycogen levels in diabetic rats subjected to acute forced swimming.

    PubMed

    Bicer, Mursel; Gunay, Mehmet; Akil, Mustafa; Avunduk, Mustafa Cihat; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim

    2011-03-01

    This study aims to examine the effect of zinc administration on liver glycogen levels of rats in which diabetes was induced with streptozotocin and which were subjected to acute swimming exercise. The study was conducted on 80 adult Sprague-Dawley male rats, which were equally allocated to eight groups: group 1, general control; group 2, zinc-administrated control; group 3, zinc-administrated diabetic control; group 4, swimming control; group 5, zinc-administrated swimming; group 6, zinc-administrated diabetic swimming; group 7, diabetic swimming; group 8, diabetic control group. In order to induce diabetes, animals were injected with 40 mg/kg intraperitoneal (ip) streptozotocin. The injections were repeated in the same dose after 24 h. Animals which had blood glucose at or above 300 mg/dl 6 days after the last injections were accepted as diabetic. Zinc was administrated ip for 4 weeks as 6 mg/kg/day per rat. Hepatic tissue samples taken from the animals at the end of the study were fixed in 95% ethyl alcohol. Cross sections of 5 µm thickness, taken by the help of a microtome from the tissue samples buried in paraffin, were placed on a microscope slide and stained with periodic acid-Schiff and evaluated by light microscope. All microscopic images were transferred to a PC and assessed with the help of Clemex PE3.5 image analysis software. The lowest liver glycogen levels in the study were obtained in groups 3, 4, 6, 7, and 8. Liver glycogen levels in group 5 were higher than groups 3, 4, 6, 7, and 8, but lower than groups 1 and 2 (p < 0.05). Groups 1 and 2 had the highest liver glycogen levels. The results obtained from the study indicate that liver glycogen levels which dropped in acute swimming exercise were restored by zinc administration and that diabetes induced in rats prevented the protective effect of zinc.

  9. Ego depletion interferes with rule-defined category learning but not non-rule-defined category learning.

    PubMed

    Minda, John P; Rabi, Rahel

    2015-01-01

    Considerable research on category learning has suggested that many cognitive and environmental factors can have a differential effect on the learning of rule-defined (RD) categories as opposed to the learning of non-rule-defined (NRD) categories. Prior research has also suggested that ego depletion can temporarily reduce the capacity for executive functioning and cognitive flexibility. The present study examined whether temporarily reducing participants' executive functioning via a resource depletion manipulation would differentially impact RD and NRD category learning. Participants were either asked to write a story with no restrictions (the control condition), or without using two common letters (the ego depletion condition). Participants were then asked to learn either a set of RD categories or a set of NRD categories. Resource depleted participants performed more poorly than controls on the RD task, but did not differ from controls on the NRD task, suggesting that self regulatory resources are required for successful RD category learning. These results lend support to multiple systems theories and clarify the role of self-regulatory resources within this theory.

  10. Ego depletion interferes with rule-defined category learning but not non-rule-defined category learning

    PubMed Central

    Minda, John P.; Rabi, Rahel

    2015-01-01

    Considerable research on category learning has suggested that many cognitive and environmental factors can have a differential effect on the learning of rule-defined (RD) categories as opposed to the learning of non-rule-defined (NRD) categories. Prior research has also suggested that ego depletion can temporarily reduce the capacity for executive functioning and cognitive flexibility. The present study examined whether temporarily reducing participants’ executive functioning via a resource depletion manipulation would differentially impact RD and NRD category learning. Participants were either asked to write a story with no restrictions (the control condition), or without using two common letters (the ego depletion condition). Participants were then asked to learn either a set of RD categories or a set of NRD categories. Resource depleted participants performed more poorly than controls on the RD task, but did not differ from controls on the NRD task, suggesting that self regulatory resources are required for successful RD category learning. These results lend support to multiple systems theories and clarify the role of self-regulatory resources within this theory. PMID:25688220

  11. Color categories only affect post-perceptual processes when same- and different-category colors are equally discriminable.

    PubMed

    He, Xun; Witzel, Christoph; Forder, Lewis; Clifford, Alexandra; Franklin, Anna

    2014-04-01

    Prior claims that color categories affect color perception are confounded by inequalities in the color space used to equate same- and different-category colors. Here, we equate same- and different-category colors in the number of just-noticeable differences, and measure event-related potentials (ERPs) to these colors on a visual oddball task to establish if color categories affect perceptual or post-perceptual stages of processing. Category effects were found from 200 ms after color presentation, only in ERP components that reflect post-perceptual processes (e.g., N2, P3). The findings suggest that color categories affect post-perceptual processing, but do not affect the perceptual representation of color.

  12. EPA Administrative Law Judge Legal Documents

    EPA Pesticide Factsheets

    This dataset contains Decisions and Orders originating from EPAs Office of Administrative Law Judges (OALJ), which is an independent office in the Office of the Administrator of the EPA. The Administrative Law Judges conduct hearings and render decisions in proceedings between the EPA and persons, businesses, government entities, and other organizations which are or are alleged to be regulated under environmental laws. Administrative Law Judges preside in enforcement and permit proceedings in accordance with the Administrative Procedure Act. Most enforcement actions initiated by the EPA are for the assessment of civil penalties. The Decisions and Orders are organized into three categories: (1) alphabetical listing by the respondent involved, (2) reverse chronological listing by date, and (3) Decisions and Orders under FIFRA Section 6. This dataset includes Decisions and Orders dating back to 1989 in the Reverse Chronological list, Decisions and Orders dating back to 1997 in the Alphabetical list, and a few Decisions and Orders dating back to 1974 under FIFRA Section 6.

  13. Management & Supervision Personnel Administration Training; General Reference.

    ERIC Educational Resources Information Center

    United States Government Printing Office, Washington, DC. Training and Career Development Div.

    This report lists 329 books in the library of the Training and Career Development Division of the Personnel Service. The books are listed under six categories. They are: personnel administration (46), management and supervision (60), general reference (57), training (20), American Management Association (AMA) publications (118), and United States…

  14. A Proposal for Excellence in Educational Administration.

    ERIC Educational Resources Information Center

    Achilles, C. M.

    Numerous 1983-84 educational improvement studies emphasized the need for strong principal leadership, yet present reform efforts fail to address adequately principal preparation. This proposal for administrative excellence has a four-category focus: recruitment of those with strong liberal arts degrees; selection of those committed to an 11-month…

  15. Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration

    PubMed Central

    Jochemsen, Roeline; Wesselman, J. G. J.; Hermans, J.; van Boxtel, C. J.; Breimer, D. D.

    1983-01-01

    1 Pharmacokinetics and bioavailability of brotizolam after i.v. and oral administration were studied in healthy young volunteers. 2 Kinetic parameters after i.v. administration were: volume of distribution 0.66 ± 0.19 1/kg, total plasma clearance 113 ± 28 ml/min, distribution half-life 11 ± 6 min, and elimination half-life 4.8 ± 1.4 h (mean values ± s.d.). 3 Kinetic parameters after oral administration were: absorption lag-time 8 ± 12 min, absorption half-life 10 ± 11 min, and elimination half-life 5.1 ± 1.2 h (mean values ± s.d.). 4 Bioavailability of brotizolam was 70 ± 22% when calculated by comparing oral and intravenous area-under-curve values, corrected for intra-individual half-life differences. An alternative calculation method, which is relatively independent of large clearance variations, provided a bioavailability of 70 ± 24% (range: 47-117%). PMID:6661374

  16. GSK1265744 pharmacokinetics in plasma and tissue after single-dose long-acting injectable administration in healthy subjects.

    PubMed

    Spreen, William; Ford, Susan L; Chen, Shuguang; Wilfret, David; Margolis, David; Gould, Elizabeth; Piscitelli, Stephen

    2014-12-15

    GSK1265744 (744) is an HIV-1 integrase inhibitor in clinical development as a long-acting (LA) injectable formulation. This study evaluated plasma and tissue pharmacokinetics after single-dose administration of 744 LA administered by intramuscular (IM) or subcutaneous injections. This was a phase I, open-label, 9-cohort, parallel study of 744 in healthy subjects. 744 was administered as a 200 mg/mL nanosuspension at doses of 100-800 mg IM and 100-400 mg subcutaneous. Eight (6 active and 2 placebo) male and female subjects participated in each of the first 7 cohorts. All 8 subjects, 4 males and 4 females, received active 744 LA in cohorts 8 and 9 and underwent rectal and cervicovaginal tissue sampling, respectively. Plasma pharmacokinetic sampling was performed for a minimum of 12 weeks or until 744 concentrations were ≤0.1 μg/mL. Rectal and cervicovaginal tissue biopsies were performed at weeks 2 and 8 (cohort 8) and weeks 4 and 12 (cohort 9). 744 LA was generally safe and well tolerated after single injections. A majority of subjects reported injection site reactions, all graded as mild in intensity. Plasma concentration-time profiles were prolonged with measureable concentrations up to 52 weeks after dosing. 744 LA 800 mg IM achieved mean concentrations above protein adjusted-IC90 for approximately 16 weeks. Rectal and cervicovaginal tissue concentrations ranged from <8% to 28% of corresponding plasma concentrations. These data suggest 744 LA injection has potential application as a monthly or less frequent HIV treatment or prevention agent.

  17. The composition of category conjunctions.

    PubMed

    Hutter, Russell R C; Crisp, Richard J

    2005-05-01

    In three experiments, the authors investigated the impression formation process resulting from the perception of familiar or unfamiliar social category combinations. In Experiment 1, participants were asked to generate attributes associated with either a familiar or unfamiliar social category conjunction. Compared to familiar combinations, the authors found that when the conjunction was unfamiliar, participants formed their impression less from the individual constituent categories and relatively more from novel emergent attributes. In Experiment 2, the authors replicated this effect using alternative experimental materials. In Experiment 3, the effect generalized to additional (orthogonally combined) gender and occupation categories. The implications of these findings for understanding the processes involved in the conjunction of social categories, and the formation of new stereotypes, are discussed.

  18. 14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

  19. 14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

  20. 14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

  1. 5 CFR 731.104 - Appointments subject to investigation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Appointments subject to investigation. 731.104 Section 731.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.104 Appointments subject to investigation. (a) To...

  2. 5 CFR 731.104 - Appointments subject to investigation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Appointments subject to investigation. 731.104 Section 731.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.104 Appointments subject to investigation. (a) To...

  3. 5 CFR 731.104 - Appointments subject to investigation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Appointments subject to investigation. 731.104 Section 731.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.104 Appointments subject to investigation. (a) To...

  4. 5 CFR 731.104 - Appointments subject to investigation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Appointments subject to investigation. 731.104 Section 731.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.104 Appointments subject to investigation. (a) To...

  5. 5 CFR 731.104 - Appointments subject to investigation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Appointments subject to investigation. 731.104 Section 731.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.104 Appointments subject to investigation. (a) To...

  6. Category and Word Search: Generalizing Search Principles to Complex Processing.

    DTIC Science & Technology

    1982-03-01

    complex processing (e.g., LaBerge & Samels, 1974; Shiffrin & Schneider, 1977). In the present paper we examine how well the major phenomena in simple visual...subjects are searching for novel characters ( LaBerge , 1973). The relatively large and rapid CH practice effects for word and category search are analogous...1974) demonstrated interference effects of irrelevant flanking letters. Shaffer and Laberge (1979) showed a similar effect with words and semantic

  7. Simplicial Descent Categories

    NASA Astrophysics Data System (ADS)

    Rodriguez Gonzalez, Beatriz

    2008-04-01

    Much of the homotopical and homological structure of the categories of chain complexes and topological spaces can be deduced from the existence and properties of the 'simple' functors Tot : {double chain complexes} -> {chain complexes} and geometric realization : {sSets} -> {Top}, or similarly, Tot : {simplicial chain complexes} -> {chain complexes} and | | : {sTop} -> {Top}. The purpose of this thesis is to abstract this situation, and to this end we introduce the notion of '(co)simplicial descent category'. It is inspired by Guillen-Navarros's '(cubical) descent categories'. The key ingredients in a (co)simplicial descent category D are a class E of morphisms in D, called equivalences, and a 'simple' functor s : {(co)simplicial objects in D} -> D. They must satisfy axioms like 'Eilenberg-Zilber', 'exactness' and 'acyclicity'. This notion covers a wide class of examples, as chain complexes, sSets, topological spaces, filtered cochain complexes (where E = filtered quasi-isomorphisms or E = E_2-isomorphisms), commutative differential graded algebras (with s = Navarro's Thom-Whitney simple), DG-modules over a DG-category and mixed Hodge complexes, where s = Deligne's simple. From the simplicial descent structure we obtain homotopical structure on D, as cone and cylinder objects. We use them to i) explicitly describe the morphisms of HoD=D[E^{-1}] similarly to the case of calculus of fractions; ii) endow HoD with a non-additive pre-triangulated structure, that becomes triangulated in the stable additive case. These results use the properties of a 'total functor', which associates to any biaugmented bisimplicial object a simplicial object. It is the simplicial analogue of the total chain complex of a double complex, and it is left adjoint to Illusie's 'decalage' functor.

  8. 76 FR 44512 - Human Subjects Research Protections: Enhancing Protections for Research Subjects and Reducing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... research enterprise, the proliferation of multi-site clinical trials and observational studies, the... and Drug Administration 21 CFR Parts 50 and 56 Human Subjects Research Protections: Enhancing Protections for Research Subjects and Reducing Burden, Delay, and Ambiguity for Investigators AGENCIES: The...

  9. Pharmacokinetics, safety, and tolerability of rotigotine transdermal system in healthy Japanese and Caucasian subjects following multiple-dose administration.

    PubMed

    Cawello, Willi; Kim, Seong Ryul; Braun, Marina; Elshoff, Jan-Peer; Masahiro, Takeuchi; Ikeda, Junji; Funaki, Tomoo

    2016-08-01

    Rotigotine is a dopamine receptor agonist indicated for the treatment of Parkinson's disease and moderate-to-severe restless legs syndrome. Continuous transdermal delivery of rotigotine via a silicon-based patch maintains stable plasma concentrations over 24 h. The objective of the study was to evaluate the pharmacokinetics, safety, and tolerability of a multiple-dose schedule of rotigotine transdermal patch in Japanese and Caucasian subjects. In this open-label, repeated-dose, parallel-group study (ClinicalTrials.gov: NCT01854216), healthy male and female subjects of Japanese or Caucasian ethnic origin were matched by gender, body mass index, and age. Subjects underwent a 9-day patch application period. 12 Japanese and 12 Caucasian subjects were included in the pharmacokinetic analyses. Mean apparent doses (actual amount of drug delivered) increased proportionally with rotigotine nominal dosages (1, 2, and 4 mg/24 h) and were similar for both ethnic groups, with large inter-individual variability. Mean plasma concentration-time profiles for unconjugated rotigotine were similar in both ethnic groups at day 3 for each dosage. Peak concentrations (C max,ss) and area under the concentration-time curves from pre-dose to the concentration measured 24 h after administration of patch (AUC(0-24,ss)) showed similar exposure in both groups; higher values in Japanese subjects were explained by differences in body weight. For total rotigotine, C max,ss and AUC(0-24,ss) values were higher in Caucasian subjects and could be explained by small differences in apparent dose. Rotigotine was generally well tolerated following multiple applications up to 4 mg/24 h. These findings suggest similar dosage requirements for rotigotine transdermal system in Japanese and Caucasian populations.

  10. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  11. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  12. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  13. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  14. Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure.

    PubMed

    De Sousa Fernandes Perna, E B; Theunissen, E L; Kuypers, K P C; Toennes, S W; Ramaekers, J G

    2016-09-01

    Alcohol and cannabis use have been implicated in aggression. Alcohol consumption is known to facilitate aggression, whereas a causal link between cannabis and aggression has not been clearly demonstrated. This study investigated the acute effects of alcohol and cannabis on subjective aggression in alcohol and cannabis users, respectively, following aggression exposure. Drug-free controls served as a reference. It was hypothesized that aggression exposure would increase subjective aggression in alcohol users during alcohol intoxication, whereas it was expected to decrease subjective aggression in cannabis users during cannabis intoxication. Heavy alcohol (n = 20) and regular cannabis users (n = 21), and controls (n = 20) were included in a mixed factorial study. Alcohol and cannabis users received single doses of alcohol and placebo or cannabis and placebo, respectively. Subjective aggression was assessed before and after aggression exposure consisting of administrations of the point-subtraction aggression paradigm (PSAP) and the single category implicit association test (SC-IAT). Testosterone and cortisol levels in response to alcohol/cannabis treatment and aggression exposure were recorded as secondary outcome measures. Subjective aggression significantly increased following aggression exposure in all groups while being sober. Alcohol intoxication increased subjective aggression whereas cannabis decreased the subjective aggression following aggression exposure. Aggressive responses during the PSAP increased following alcohol and decreased following cannabis relative to placebo. Changes in aggressive feeling or response were not correlated to the neuroendocrine response to treatments. It is concluded that alcohol facilitates feelings of aggression whereas cannabis diminishes aggressive feelings in heavy alcohol and regular cannabis users, respectively.

  15. Handbook for Alumni Administration.

    ERIC Educational Resources Information Center

    Webb, Charles H., Ed.

    A definitive look at the field of alumni administration is presented, noting that the subject has until now received little attention. The 34 chapters are divided into nine sections: an overview of alumni administration; alumni as an essential resource; people management; budget and records; programming; communications; alumni education programs…

  16. Models as Relational Categories

    NASA Astrophysics Data System (ADS)

    Kokkonen, Tommi

    2017-11-01

    Model-based learning (MBL) has an established position within science education. It has been found to enhance conceptual understanding and provide a way for engaging students in authentic scientific activity. Despite ample research, few studies have examined the cognitive processes regarding learning scientific concepts within MBL. On the other hand, recent research within cognitive science has examined the learning of so-called relational categories. Relational categories are categories whose membership is determined on the basis of the common relational structure. In this theoretical paper, I argue that viewing models as relational categories provides a well-motivated cognitive basis for MBL. I discuss the different roles of models and modeling within MBL (using ready-made models, constructive modeling, and generative modeling) and discern the related cognitive aspects brought forward by the reinterpretation of models as relational categories. I will argue that relational knowledge is vital in learning novel models and in the transfer of learning. Moreover, relational knowledge underlies the coherent, hierarchical knowledge of experts. Lastly, I will examine how the format of external representations may affect the learning of models and the relevant relations. The nature of the learning mechanisms underlying students' mental representations of models is an interesting open question to be examined. Furthermore, the ways in which the expert-like knowledge develops and how to best support it is in need of more research. The discussion and conceptualization of models as relational categories allows discerning students' mental representations of models in terms of evolving relational structures in greater detail than previously done.

  17. 45 CFR Subject Index to Title Ix... - Subject Index to Title IX Preamble and Regulation \\1\\

    Code of Federal Regulations, 2010 CFR

    1998-10-01

    ... 45 Public Welfare 1 1998-10-01 1998-10-01 false Subject Index to Title IX Preamble and Regulation \\1\\ Index Subject Index to Title IX Preamble and Regulation \\1\\ GENERAL ADMINISTRATION... FINANCIAL ASSISTANCE Procedures [Interim] Interim procedures. Pt. 86, Index Subject Index to Title IX...

  18. 45 CFR Subject Index to Title Ix... - Subject Index to Title IX Preamble and Regulation \\1\\

    Code of Federal Regulations, 2010 CFR

    1997-10-01

    ... 45 Public Welfare 1 1997-10-01 1997-10-01 false Subject Index to Title IX Preamble and Regulation \\1\\ Index Subject Index to Title IX Preamble and Regulation \\1\\ GENERAL ADMINISTRATION... FINANCIAL ASSISTANCE Procedures [Interim] Interim procedures. Pt. 86, Index Subject Index to Title IX...

  19. 76 FR 31171 - Importation of Plants for Planting; Establishing a Category of Plants for Planting Not Authorized...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ...We are amending the regulations to establish a new category of regulated articles in the regulations governing the importation of nursery stock, also known as plants for planting. This category will list taxa of plants for planting whose importation is not authorized pending pest risk analysis. If scientific evidence indicates that a taxon of plants for planting is a quarantine pest or a host of a quarantine pest, we will publish a notice that will announce our determination that the taxon is a quarantine pest or a host of a quarantine pest, cite the scientific evidence we considered in making this determination, and give the public an opportunity to comment on our determination. If we receive no comments that change our determination, the taxon will subsequently be added to the new category. We will allow any person to petition for a pest risk analysis to be conducted to consider whether to remove a taxon that has been added to the new category. After the pest risk analysis is completed, we will remove the taxon from the category and allow its importation subject to general requirements, allow its importation subject to specific restrictions, or prohibit its importation. We will consider applications for permits to import small quantities of germplasm from taxa whose importation is not authorized pending pest risk analysis, for experimental or scientific purposes under controlled conditions. This new category will allow us to take prompt action on evidence that the importation of a taxon of plants for planting poses a risk while continuing to allow for public participation in the process.

  20. Effect of administration of corticotropin-releasing hormone and glucocorticoid on arginine vasopressin response to osmotic stimulus in normal subjects and patients with hypocorticotropinism without overt diabetes insipidus.

    PubMed

    Yamada, K; Tamura, Y; Yoshida, S

    1989-08-01

    We examined the effect of CRH administration on the response of plasma arginine vasopressin (AVP) induced by an osmotic stimulus in six normal subjects and five patients with hypocorticotropinism without overt diabetes insipidus (four patients with Sheehan's syndrome and one with idiopathic pituitary dwarfism with ACTH deficiency). Hypertonic saline infusion (855 mmol/L saline solutions at a rate of 205 mumol/kg.min for 10 min) increased plasma AVP 5.7-fold (P less than 0.01) in normal subjects and 2.4-fold (P less than 0.05) in the patients. CRH administration significantly augmented the plasma AVP response to the osmotic stimulus in the normal subjects, but not in the patients with hypocorticotropinism. CRH administration alone did not influence plasma AVP. These findings suggest that a central CRH-related mechanism(s) was at least partly involved in the augmentation of AVP release. Based on the relatively low plasma AVP response to the osmotic stimulus in patients and their lower plasma AVP levels and higher plasma osmolality under basal conditions, we suggest that patients with hypocorticotropinism have partial diabetes insipidus, in which impairment of central CRH action might be, at least in part, involved. The response of plasma AVP to the osmotic stimulus was attenuated significantly when the patients were given cortisol. Since basal PRA, plasma aldosterone, plasma osmolality, hematocrit, body weight, mean blood pressure, and heart rate were similar with and without cortisol administration, this effect of cortisol may have been due to central suppression of the AVP response to the osmotic stimulus.

  1. Administration Modifications on the WISC-R Performance Scale with Different Categories of Deaf Children.

    ERIC Educational Resources Information Center

    Sullivan, Patricia M.

    1982-01-01

    Two studies investigated the effects of administration modifications on subtest scaled scores of the Wechsler-Intelligence Scale for Children-Revised (WISC-R). Performance scale rated different groups of 57 severely/profoundly hearing-impaired children. Total communication was found to result in higher scores on all subtests in the genetic and…

  2. ELECTROCARDIOGRAPHIC CHANGES IN RABBITS SUBJECTED TO THE CHRONIC ACTION OF RADIOACTIVE ZINC DURING INTRAVENOUS ADMINISTRATION OF ADRENALINE AND INHALATION OF AMMONIA (in Russian)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ovakimov, V.G.; Bibikhin, L.N.; Saitanov, A.O.

    1963-09-01

    The employment of pharmacological loadings (administration of adrenaline and inhalation of ammonia) in rabbits subjected to the chronic action of radioactive zinc (1 and 10 mu C/kg) disclosed changes in the sensitivity of adrenoreactive systems of the myocardium (in adrenaline test) and an altered intensity and duration of reflex bradycardia (in ammonia test). (auth)

  3. Subjective Age Correlates: A Research Note.

    ERIC Educational Resources Information Center

    Barak, Benny; Stern, Barbara

    1986-01-01

    Five types of measures have been used to assess subjective age: identity age, comparative age, feel/age, cognitive age, and stereotype age. Bivariate and multivariate studies revealed four categories of correlates of self-perceived age: biological and physiological, demographic, psychographic and social psychological, and behavioral. (Author/ABB)

  4. Data categories for marine planning

    USGS Publications Warehouse

    Lightsom, Frances L.; Cicchetti, Giancarlo; Wahle, Charles M.

    2015-01-01

    The U.S. National Ocean Policy calls for a science- and ecosystem-based approach to comprehensive planning and management of human activities and their impacts on America’s oceans. The Ocean Community in Data.gov is an outcome of 2010–2011 work by an interagency working group charged with designing a national information management system to support ocean planning. Within the working group, a smaller team developed a list of the data categories specifically relevant to marine planning. This set of categories is an important consensus statement of the breadth of information types required for ocean planning from a national, multidisciplinary perspective. Although the categories were described in a working document in 2011, they have not yet been fully implemented explicitly in online services or geospatial metadata, in part because authoritative definitions were not created formally. This document describes the purpose of the data categories, provides definitions, and identifies relations among the categories and between the categories and external standards. It is intended to be used by ocean data providers, managers, and users in order to provide a transparent and consistent framework for organizing and describing complex information about marine ecosystems and their connections to humans.

  5. 77 FR 29564 - Revisions to the Export Administration Regulations: Auxiliary and Miscellaneous Items That No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ...The Bureau of Industry and Security (BIS) publishes this action to propose how auxiliary and miscellaneous military equipment and related articles the President determines no longer warrant control under Category XIII (Auxiliary Military Equipment) of the United States Munitions List (USML) would be controlled under the Commerce Control List (CCL) in new Export Control Classification Numbers (ECCNs) 0A617, 0B617, 0C617, 0D617, and 0E617 as part of the proposed new ``600 series'' of ECCNs. This rule proposes also to integrate into those five new ECCNs items within the scope of Wassenaar Arrangement Munitions List (WAML) Category 17 that would be removed from the USML, or that are not specifically identified on the USML or CCL but that are currently subject to USML jurisdiction. Finally, this rule proposes to control some items now classified under ECCNs 0A018, 0A918 and 0E018 under new ECCNs 0A617 and 0E617. This action would consolidate the above- mentioned auxiliary and miscellaneous military equipment and related articles on the CCL in the proposed new ``600 series.'' This rule is one of a planned series proposing how various types of articles that the President determines, as part of the Administration's Export Control Reform Initiative, no longer warrant control on the USML under the International Traffic in Arms Regulations (ITAR), would be controlled on the CCL in accordance with the requirements of the Export Administration Regulations (EAR). This proposed rule is being published in conjunction with a proposed rule from the Department of State, Directorate of Defense Trade Controls, which would amend the list of articles controlled by USML Category XIII.

  6. Improving menu categories.

    PubMed

    2004-09-01

    No matter how good a site's navigational tools, site visitors will not use them if the menu categories are ambiguous. Users have to know what to expect when they click on a particular menu item. If the categories are not intuitive, users will have to resort to the site's search engine, ignoring the entire structure. The Pennsylvania Medical Society site (http://www.pamedsoc.org) had been plagued with poor menu labels until it took a step back and improved them.

  7. 45 CFR Subject Index to Title Ix... - Subject Index to Title IX Preamble and Regulation 1

    Code of Federal Regulations, 2010 CFR

    2002-10-01

    ... 45 Public Welfare 1 2002-10-01 2002-10-01 false Subject Index to Title IX Preamble and Regulation 1 Index Subject Index to Title IX Preamble and Regulation 1 Public Welfare GENERAL ADMINISTRATION... FINANCIAL ASSISTANCE Procedures [Interim] Interim procedures. Pt. 86, Index Subject Index to Title IX...

  8. Rapid identification of anonymous subjects in large criminal databases: problems and solutions in IAFIS III/FBI subject searches

    NASA Astrophysics Data System (ADS)

    Kutzleb, C. D.

    1997-02-01

    The high incidence of recidivism (repeat offenders) in the criminal population makes the use of the IAFIS III/FBI criminal database an important tool in law enforcement. The problems and solutions employed by IAFIS III/FBI criminal subject searches are discussed for the following topics: (1) subject search selectivity and reliability; (2) the difficulty and limitations of identifying subjects whose anonymity may be a prime objective; (3) database size, search workload, and search response time; (4) techniques and advantages of normalizing the variability in an individual's name and identifying features into identifiable and discrete categories; and (5) the use of database demographics to estimate the likelihood of a match between a search subject and database subjects.

  9. Categories and Music Transmission

    ERIC Educational Resources Information Center

    Gatien, Greg

    2009-01-01

    Lucy Green's (2008) "Music, Informal Learning, and the School: A New Classroom Pedagogy" gives rise to an interesting corollary. Does the manner of music's transmission inform one's understanding of a musical category? While categories of music can be difficult to define according to strict musical characteristics, a better understanding of…

  10. 21 CFR 21.31 - Records stored by the National Archives and Records Administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Records stored by the National Archives and Records Administration. 21.31 Section 21.31 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY Requirements for Specific Categories of Records...

  11. Pharmacokinetics of Diclofenac and Hydroxypropyl‐β‐Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD‐Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment

    PubMed Central

    Hamilton, Douglas A.; Ernst, Cynthia C.; Kramer, William G.; Madden, Donna; Lang, Eric; Liao, Edward; Lacouture, Peter G.; Ramaiya, Atulkumar

    2017-01-01

    Abstract Given their established analgesic properties, nonsteroidal anti‐inflammatory drugs (NSAIDs) represent an important postoperative pain management option. This study investigated: (1) the effects of mild or moderate renal insufficiency and mild hepatic impairment on the pharmacokinetics (PK) of diclofenac and hydroxypropyl‐β‐cyclodextrin (HPβCD) following administration of the injectable NSAID HPβCD‐diclofenac; and (2) the PK of HPβCD following administration of HPβCD‐diclofenac and intravenous itraconazole formulated with HPβCD in healthy adults. Diclofenac clearance (CL) and volume of distribution (Vz) tended to increase with decreasing renal function (moderate insufficiency versus mild insufficiency or healthy controls). Regression analysis demonstrated a significant relationship between Vz (but not CL or elimination half‐life, t½) and renal function. HPβCD CL was significantly decreased in subjects with renal insufficiency, with a corresponding increase in t½. There were no significant differences in diclofenac or HPβCD PK in subjects with mild hepatic impairment versus healthy subjects. Exposure to HPβCD in healthy subjects following HPβCD‐diclofenac administration was ∼12% of that with intravenous itraconazole, after adjusting for dosing schedule and predicted accumulation (<5% without adjustment). With respect to PK properties, these results suggest that HPβCD‐diclofenac might be administered to patients with mild or moderate renal insufficiency or mild hepatic impairment without dose adjustment (NCT00805090). PMID:29197175

  12. Reduced Sodium Transport With Nasal Administration of the Prostasin Inhibitor Camostat in Subjects With Cystic Fibrosis

    PubMed Central

    Reeves, Ginger; Hathorne, Heather; Solomon, G. Martin; Abbi, Smita; Renard, Didier; Lock, Ruth; Zhou, Ping; Danahay, Henry; Clancy, John P.; Waltz, David A.

    2013-01-01

    Background: Prostasin, a trypsin-like serine protease, is a channel-activating protease and major regulator of epithelial sodium channel-mediated sodium absorption. Its direct inhibition by camostat represents a potential approach to inhibiting sodium transport in cystic fibrosis (CF). Methods: To determine whether a topical formulation of camostat represents an efficacious and tolerable approach to reducing Na+ transport in the CF airway, we conducted a two-part randomized, double-blind, placebo-controlled, crossover, ascending single-dose study to evaluate the pharmacodynamics, safety, and pharmacokinetics of camostat administered through a nasal spray pump in subjects with CF. Nasal potential difference (PD) was measured before and after treatment, and safety and pharmacokinetics were assessed by a standardized approach. Results: In part 1, nine subjects were enrolled, and six completed crossover dosing at the maximally tolerated dose. The change in maximal (most polarizing) basal PD 2 h following administration of camostat was +13.1 mV (1.6-mg dose group) compared with −8.6 mV following placebo (P < .005). Intrasubject change in Ringer and amiloride-sensitive PDs exhibited similar and consistent responses. Bayesian analysis in an additional six subjects in part 2 estimated a dose of 18 μg/mL to provide 50% of the maximum effect. There was no significant change in chloride transport or total nasal symptom score, nasal examination rating, and laboratory parameters. Conclusions: This study establishes the proof of concept that a reduction in sodium transport in the human CF airway can be achieved through inhibition of prostasin activity, identifying a potential therapeutic target in the disease. Trial registration: ClinicalTrials.gov; No.: NCT00506792; URL: www.clinicaltrials.gov PMID:23412700

  13. Incremental Bayesian Category Learning From Natural Language.

    PubMed

    Frermann, Lea; Lapata, Mirella

    2016-08-01

    Models of category learning have been extensively studied in cognitive science and primarily tested on perceptual abstractions or artificial stimuli. In this paper, we focus on categories acquired from natural language stimuli, that is, words (e.g., chair is a member of the furniture category). We present a Bayesian model that, unlike previous work, learns both categories and their features in a single process. We model category induction as two interrelated subproblems: (a) the acquisition of features that discriminate among categories, and (b) the grouping of concepts into categories based on those features. Our model learns categories incrementally using particle filters, a sequential Monte Carlo method commonly used for approximate probabilistic inference that sequentially integrates newly observed data and can be viewed as a plausible mechanism for human learning. Experimental results show that our incremental learner obtains meaningful categories which yield a closer fit to behavioral data compared to related models while at the same time acquiring features which characterize the learned categories. (An earlier version of this work was published in Frermann and Lapata .). Copyright © 2015 Cognitive Science Society, Inc.

  14. 21 CFR 20.110 - Data and information about Food and Drug Administration employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Data and information about Food and Drug Administration employees. 20.110 Section 20.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.110...

  15. Utility of the T-SPOT®.TB test's borderline category to increase test resolution for results around the cut-off point.

    PubMed

    Rego, Karen; Pereira, Kristen; MacDougall, James; Cruikshank, William

    2018-01-01

    Accurate identification of individuals with TB infection, is required to achieve the WHO's End TB Strategy goals. While there is general acceptance that the T-SPOT.TB test borderline category provides an opportunity to increase test resolution of results around the test cut-off point, this has not been investigated. 645,947 tests were analyzed to determine frequency of borderline results, effect of age and time between tests and associations between subjects' clinical risk factors and retest results. 645,947 tests produced 93.5% negatives, 4% positives, 0.6% invalids, and 1.8% borderlines. Within the borderline results, 5044 were repeated, with 59.2%, 20.0% and 20.2% resolving to negative, positive and borderline, respectively. Age of subject did not affect retest results; however, time between tests indicated that retest resolution occurred with greatest frequency after 90 days. TB risk factors were provided for 2640 subjects and 17% of low risk subjects with a high initial borderline resolved to negative while 27.6% of subjects with high risk and an initial low borderline resolved to positive, suggesting that these subjects could have been inappropriately classified if using a single cut-off point test with no borderline category. This study demonstrates the utility of the T-SPOT.TB test's borderline category to increase test resolution around the test cut-off point. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

  17. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

  18. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

  19. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

  20. 40 CFR 73.84 - Administrator's action on applications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

  1. Dissociative semantic breakdown in Alzheimer's disease: evidence from multiple category fluency test.

    PubMed

    Ting, Simon Kang Seng; Hameed, Shahul; Earnest, Arul; Tan, Eng-King

    2013-07-01

    Category-specific semantic dissociation particularly in terms of biological and non-biological dichotomy has been described in Alzheimer's disease (AD). We re-examine above finding by performing multiple superordinate category verbal fluency test in AD patients. We analyze the baseline neuropsychological assessment performance of food and animal fluency test of AD patients from a tertiary hospital that collected prospectively over 5 years period and correlation was calculated by Kappa test. The analysis is stratified according to literacy level (primary: 0-6 years education and secondary: >6 years education) and disease severity (MMSE score: mild 19-24, moderate 13-18 and severe <13). A total of 296 AD patients were analyzed and only fair to moderate agreement between food and animal category fluency test was found especially in the mild AD cases (primary: kappa 0.42; secondary: kappa 0.40). Kappa agreement level increases when disease progress especially in the secondary education group. Food category, which is a more relevant semantic knowledge to Singapore population, is generally more affected. Higher educated subjects appeared to have less semantic dissociation effect when disease progress. Despite less primed in daily life, biological category of semantic knowledge appears to be affected less during AD process in highly urbanized Singapore society. Brain appears to have special protective mechanism towards living things. However, education level seems have a modulation effect towards the biological protective mechanism. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. 75 FR 70854 - Harmonization of Various Airworthiness Standards for Transport Category Airplanes-Flight Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ..., deploy speed brakes) to stop the airplane within the accelerate stop distance. It also means the minimum... flight diving speed. List of Subjects in 14 CFR Part 25 Aircraft, Aviation safety, Reporting and... transport category airplanes. This action would harmonize the requirements for takeoff speeds, static...

  3. Right away: A late, right-lateralized category effect complements an early, left-lateralized category effect in visual search.

    PubMed

    Constable, Merryn D; Becker, Stefanie I

    2017-10-01

    According to the Sapir-Whorf hypothesis, learned semantic categories can influence early perceptual processes. A central finding in support of this view is the lateralized category effect-namely, the finding that categorically different colors (e.g., blue and green hues) can be discriminated faster than colors within the same color category (e.g., different hues of green), especially when they are presented in the right visual field. Because the right visual field projects to the left hemisphere, this finding has been popularly couched in terms of the left-lateralization of language. However, other studies have reported bilateral category effects, which has led some researchers to question the linguistic origins of the effect. Here we examined the time course of lateralized and bilateral category effects in the classical visual search paradigm by means of eyetracking and RT distribution analyses. Our results show a bilateral category effect in the manual responses, which is combined of an early, left-lateralized category effect and a later, right-lateralized category effect. The newly discovered late, right-lateralized category effect occurred only when observers had difficulty locating the target, indicating a specialization of the right hemisphere to find categorically different targets after an initial error. The finding that early and late stages of visual search show different lateralized category effects can explain a wide range of previously discrepant findings.

  4. The helpfulness of category labels in semi-supervised learning depends on category structure.

    PubMed

    Vong, Wai Keen; Navarro, Daniel J; Perfors, Amy

    2016-02-01

    The study of semi-supervised category learning has generally focused on how additional unlabeled information with given labeled information might benefit category learning. The literature is also somewhat contradictory, sometimes appearing to show a benefit to unlabeled information and sometimes not. In this paper, we frame the problem differently, focusing on when labels might be helpful to a learner who has access to lots of unlabeled information. Using an unconstrained free-sorting categorization experiment, we show that labels are useful to participants only when the category structure is ambiguous and that people's responses are driven by the specific set of labels they see. We present an extension of Anderson's Rational Model of Categorization that captures this effect.

  5. Concomitant administration of fluoxetine and amantadine modulates the activity of peritoneal macrophages of rats subjected to a forced swimming test.

    PubMed

    Roman, Adam; Rogóz, Zofia; Kubera, Marta; Nawrat, Dominika; Nalepa, Irena

    2009-01-01

    Recent studies show that administration of a non-competitive NMDA receptor antagonist, amantadine (AMA), potentiates the action of antidepressant drugs. Since antidepressants may modulate functioning of the immune system and activation of a pro-inflammatory response in depressive disorders is frequently reported, the aim of the present study was to examine whether a combined administration of AMA and the antidepressant, fluoxetine (FLU), to rats subsequently subjected to a forced swimming test (FST) modifies the parameters of macrophage activity, directly related to their immunomodulatory functions, i.e., arginase (ARG) activity and synthesis of nitric oxide (NO). We found that 10 mg/kg AMA and 10 mg/kg FLU, ineffective in FST for antidepressant-like activity when administered alone, increased the ARG/NO ratio in macrophages when administered concomitantly. This effect was accompanied by a decrease of cellular adherence. Concurrently, the basal metabolic activity of the cells measured with reduction of resazurin, and intracellular host defense as assessed by a synthesis of superoxide anion, were not affected by such antidepressive treatment. Our data indicate that co-administration of AMA and FLU decreases the pro-inflammatory properties of macrophages and causes a redirection of immune response toward anti-inflammatory activity, as one can anticipate in the case of an effective antidepressive treatment.

  6. 7 CFR 701.1 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Administration. 701.1 Section 701.1 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE... ADMINISTERED UNDER THIS PART § 701.1 Administration. (a) Subject to the availability of funds, this part...

  7. 40 CFR 63.11514 - Am I subject to this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 15 2013-07-01 2013-07-01 false Am I subject to this subpart? 63.11514 Section 63.11514 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Finishing Source Categories Applicability and Compliance Dates § 63.11514 Am I subject to this...

  8. 40 CFR 63.11514 - Am I subject to this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 14 2011-07-01 2011-07-01 false Am I subject to this subpart? 63.11514 Section 63.11514 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Finishing Source Categories Applicability and Compliance Dates § 63.11514 Am I subject to this...

  9. 40 CFR 63.11514 - Am I subject to this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 15 2012-07-01 2012-07-01 false Am I subject to this subpart? 63.11514 Section 63.11514 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Finishing Source Categories Applicability and Compliance Dates § 63.11514 Am I subject to this...

  10. 40 CFR 63.11514 - Am I subject to this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 15 2014-07-01 2014-07-01 false Am I subject to this subpart? 63.11514 Section 63.11514 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Finishing Source Categories Applicability and Compliance Dates § 63.11514 Am I subject to this...

  11. Positive predictive value between medical-chart body-mass-index category and obesity versus codes in a claims-data warehouse.

    PubMed

    Caplan, Eleanor O; Kamble, Pravin S; Harvey, Raymond A; Smolarz, B Gabriel; Renda, Andrew; Bouchard, Jonathan R; Huang, Joanna C

    2018-01-01

    To evaluate the positive predictive value of claims-based V85 codes for identifying individuals with varying degrees of BMI relative to their measured BMI obtained from medical record abstraction. This was a retrospective validation study utilizing administrative claims and medical chart data from 1 January 2009 to 31 August 2015. Randomly selected samples of patients enrolled in a Medicare Advantage Prescription Drug (MAPD) or commercial health plan and with a V85 claim were identified. The claims-based BMI category (underweight, normal weight, overweight, obese class I-III) was determined via corresponding V85 codes and compared to the BMI category derived from chart abstracted height, weight and/or BMI. The positive predictive values (PPVs) of the claims-based BMI categories were calculated with the corresponding 95% confidence intervals (CIs). The overall PPVs (95% CIs) in the MAPD and commercial samples were 90.3% (86.3%-94.4%) and 91.1% (87.3%-94.9%), respectively. In each BMI category, the PPVs (95% CIs) for the MAPD and commercial samples, respectively, were: underweight, 71.0% (55.0%-87.0%) and 75.9% (60.3%-91.4%); normal, 93.8% (85.4%-100%) and 87.8% (77.8%-97.8%); overweight, 97.4% (92.5%-100%) and 93.5% (84.9%-100%); obese class I, 96.9 (90.9%-100%) and 97.2% (91.9%-100%); obese class II, 97.0% (91.1%-100%) and 93.0% (85.4%-100%); and obese class III, 85.0% (73.3%-96.1%) and 97.1% (91.4%-100%). BMI categories derived from administrative claims, when available, can be used successfully particularly in the context of obesity research.

  12. Comparison of pediatric cardiac surgical mortality rates from national administrative data to contemporary clinical standards.

    PubMed

    Welke, Karl F; Diggs, Brian S; Karamlou, Tara; Ungerleider, Ross M

    2009-01-01

    Despite the superior coding and risk adjustment of clinical data, the ready availability, national scope, and perceived unbiased nature of administrative data make it the choice of governmental agencies and insurance companies for evaluating quality and outcomes. We calculated pediatric cardiac surgery mortality rates from administrative data and compared them with widely quoted standards from clinical databases. Pediatric cardiac surgical operations were retrospectively identified by ICD-9-CM diagnosis and procedure codes from the Nationwide Inpatient Sample (NIS) 1988-2005 and the Kids' Inpatient Database (KID) 2003. Cases were grouped into Risk Adjustment for Congenital Heart Surgery, version 1 (RACHS-1) categories. In-hospital mortality rates and 95% confidence intervals were calculated. A total of 55,164 operations from the NIS and 10,945 operations from the KID were placed into RACHS-1 categories. During the 18-year period, the overall NIS mortality rate for pediatric cardiac surgery decreased from 8.7% (95% confidence interval, 8.0% to 9.3%) to 4.6% (95% confidence interval, 4.3% to 5.0%). Mortality rates by RACHS-1 category decreased significantly as well. The KID and NIS mortality rates from comparable years were similar. Overall mortality rates derived from administrative data were higher than those from contemporary national clinical data, The Society of Thoracic Surgeons Congenital Heart Surgery Database, or published data from pediatric cardiac specialty centers. Although category-specific mortality rates were higher in administrative data than in clinical data, a minority of the relationships reached statistical significance. Despite substantial improvement, mortality rates from administrative data remain higher than those from clinical data. The discrepancy may be attributable to several factors: differences in database design and composition, differences in data collection and reporting structures, and variation in data quality.

  13. 7 CFR 253.11 - Administrative funds for State agencies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Section 253.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION.... Administrative costs must be included in annual or revised budget information submitted by the State agency to... beginning of a Federal fiscal year. The application shall include budget information, reflecting by category...

  14. 7 CFR 253.11 - Administrative funds for State agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Section 253.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION.... Administrative costs must be included in annual or revised budget information submitted by the State agency to... beginning of a Federal fiscal year. The application shall include budget information, reflecting by category...

  15. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories... airplanes that have a seating configuration, excluding pilot seats, of nine or less, a maximum certificated...

  16. 14 CFR 17.11 - Matters not subject to protest.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Acquisition: (a) FAA purchases from or through, state, local, and tribal governments and public authorities...) Other transactions which do not fall into the category of procurement contracts subject to the AMS. ...

  17. 76 FR 34120 - Action Subject to Intergovernmental Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 39 existing...

  18. 76 FR 34119 - Action Subject to Intergovernmental Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 22 existing...

  19. Pacific Northwest National Laboratory Potential Impact Categories for Radiological Air Emission Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ballinger, Marcel Y.; Gervais, Todd L.; Barnett, J. Matthew

    2012-06-05

    In 2002, the EPA amended 40 CFR 61 Subpart H and 40 CFR 61 Appendix B Method 114 to include requirements from ANSI/HPS N13.1-1999 Sampling and Monitoring Releases of Airborne Radioactive Substances from the Stack and Ducts of Nuclear Facilities for major emission points. Additionally, the WDOH amended the Washington Administrative Code (WAC) 246-247 Radiation protection-air emissions to include ANSI/HPS N13.1-1999 requirements for major and minor emission points when new permitting actions are approved. A result of the amended regulations is the requirement to prepare a written technical basis for the radiological air emission sampling and monitoring program. A keymore » component of the technical basis is the Potential Impact Category (PIC) assigned to an emission point. This paper discusses the PIC assignments for the Pacific Northwest National Laboratory (PNNL) Integrated Laboratory emission units; this revision includes five PIC categories.« less

  20. Picture reality decision, semantic categories and gender. A new set of pictures, with norms and an experimental study.

    PubMed

    Barbarotto, Riccardo; Laiacona, Marcella; Macchi, Valeria; Capitani, Erminio

    2002-01-01

    We present a new corpus of 80 pictures of unreal objects, useful for a controlled assessment of object reality decision. The new pictures were assembled from parts of the Snodgrass and Vanderwart [J. Exp. Psychol., Hum. Learning Memory 6; 1980: 174] set and were devised for the purpose of contrasting natural categories (animals, fruits and vegetables), artefacts (tools, vehicles and furniture), body parts and musical instruments. We examined 140 normal subjects in a free-choice and a multiple-choice object decision task, assembled with 80 pictures of real objects and above 80 new pictures of unreal objects in order to obtain a difficulty index for each picture. We found that the tasks were more difficult with pictures representing natural entities than with pictures of artefacts. We found a gender by category interaction, with a female superiority with some natural categories (fruits and vegetables, but not animals), and a male advantage with artefacts. On this basis, the difficulty index we calculated for each picture is separately reported for males and females. We discuss the possible origin of the gender effect, which has been found with the same categories in other tasks and has a counterpart in the different familiarity of the stimuli for males and females. In particular, we contrast explanations based on socially determined gender differences with accounts based on evolutionary pressures. We further comment on the relationship between data from normal subjects and the domain-specific account of semantic category dissociations observed in brain-damaged patients.

  1. Administrative Preparation: A Critical Appraisal

    ERIC Educational Resources Information Center

    Bridges, Edwin M.

    1976-01-01

    How strong a case can universities make for formal preparation as a major determinant of an individual's right to pursue a career in educational administration? Examines research bearing on the subject and analyzes the degree of fit between the "work" of a student and the work of an administrator. (Author/RK)

  2. Decoding word and category-specific spatiotemporal representations from MEG and EEG

    PubMed Central

    Chan, Alexander M.; Halgren, Eric; Marinkovic, Ksenija; Cash, Sydney S.

    2010-01-01

    The organization and localization of lexico-semantic information in the brain has been debated for many years. Specifically, lesion and imaging studies have attempted to map the brain areas representing living versus non-living objects, however, results remain variable. This may be due, in part, to the fact that the univariate statistical mapping analyses used to detect these brain areas are typically insensitive to subtle, but widespread, effects. Decoding techniques, on the other hand, allow for a powerful multivariate analysis of multichannel neural data. In this study, we utilize machine-learning algorithms to first demonstrate that semantic category, as well as individual words, can be decoded from EEG and MEG recordings of subjects performing a language task. Mean accuracies of 76% (chance = 50%) and 83% (chance = 20%) were obtained for the decoding of living vs. non-living category or individual words respectively. Furthermore, we utilize this decoding analysis to demonstrate that the representations of words and semantic category are highly distributed both spatially and temporally. In particular, bilateral anterior temporal, bilateral inferior frontal, and left inferior temporal-occipital sensors are most important for discrimination. Successful intersubject and intermodality decoding shows that semantic representations between stimulus modalities and individuals are reasonably consistent. These results suggest that both word and category-specific information are present in extracranially recorded neural activity and that these representations may be more distributed, both spatially and temporally, than previous studies suggest. PMID:21040796

  3. Pharmacokinetic comparison of a fixed-dose combination versus concomitant administration of fimasartan, amlodipine, and rosuvastatin using partial replicated design in healthy adult subjects.

    PubMed

    Oh, Minkyung; Ghim, Jong-Lyul; Park, Sung-Eun; Kim, Eun-Young; Shin, Jae-Gook

    2018-01-01

    The aim of this study was to compare the pharmacokinetics (PK) and safety profiles of a fixed-dose combination (FDC) formulation of fimasartan, amlodipine, and rosuvastatin with the co-administration of the two products by using a replicated crossover study design in healthy male subjects. This was an open-label, randomized, three-sequence, three-period replicated crossover study in healthy male subjects. The replicated crossover design was done because of high coefficient of variation of PK parameter for fimasartan, that is, >30%. With a 14 days washout period, an FDC tablet containing 60 mg fimasartan, 10 mg amlodipine, and 20 mg rosuvastatin was administered only once, and separate formulations of fimasartan/amlodipine 60 mg/10 mg FDC tablet and 20 mg rosuvastatin tablet administered twice. Blood samples were collected up to 72 hours following drug administration. The plasma concentrations of fimasartan, amlodipine, and rosuvastatin were measured by liquid chromatography tandem mass spectrometry. Safety was assessed by evaluating vital signs, clinical laboratory parameters, physical examinations, and medical interviews. The geometric mean ratios and 90% confidence intervals (CIs) for the maximum plasma concentration (C max ) and area under the curve from time zero to the last measurable sampling time (AUC t ) were 1.0776 (0.9201-1.2622) and 0.9978 (0.9538-1.0439) for fimasartan, 1.0038 (0.9782-1.0301) and 1.0055 (0.9828-1.0288) for amlodipine, and 1.0006 (0.9290-1.0776) and 0.9986 (0.9532-1.0461) for rosuvastatin, respectively. A total of 22 adverse events (AEs) were reported by 60 subjects; there were no significant differences in the incidence of AEs between the two groups. The 90% CI of the C max of fimasartan was within the widened acceptance limit, ln(0.6984)-ln(1.4319). The 90% CIs of the other PK parameters for drugs were between ln(0.8) and ln(1.25). These results suggest that the FDC formulation is pharmacokinetically bioequivalent and has a similar

  4. 14 CFR 29.79 - Landing: Category A.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Landing: Category A. 29.79 Section 29.79... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.79 Landing: Category A. (a) For Category A rotorcraft— (1) The landing performance must be determined and scheduled so that if the critical engine fails...

  5. Typicality Mediates Performance during Category Verification in Both Ad-Hoc and Well-Defined Categories

    ERIC Educational Resources Information Center

    Sandberg, Chaleece; Sebastian, Rajani; Kiran, Swathi

    2012-01-01

    Background: The typicality effect is present in neurologically intact populations for natural, ad-hoc, and well-defined categories. Although sparse, there is evidence of typicality effects in persons with chronic stroke aphasia for natural and ad-hoc categories. However, it is unknown exactly what influences the typicality effect in this…

  6. Deep-learning-based classification of FDG-PET data for Alzheimer's disease categories

    NASA Astrophysics Data System (ADS)

    Singh, Shibani; Srivastava, Anant; Mi, Liang; Caselli, Richard J.; Chen, Kewei; Goradia, Dhruman; Reiman, Eric M.; Wang, Yalin

    2017-11-01

    Fluorodeoxyglucose (FDG) positron emission tomography (PET) measures the decline in the regional cerebral metabolic rate for glucose, offering a reliable metabolic biomarker even on presymptomatic Alzheimer's disease (AD) patients. PET scans provide functional information that is unique and unavailable using other types of imaging. However, the computational efficacy of FDG-PET data alone, for the classification of various Alzheimers Diagnostic categories, has not been well studied. This motivates us to correctly discriminate various AD Diagnostic categories using FDG-PET data. Deep learning has improved state-of-the-art classification accuracies in the areas of speech, signal, image, video, text mining and recognition. We propose novel methods that involve probabilistic principal component analysis on max-pooled data and mean-pooled data for dimensionality reduction, and multilayer feed forward neural network which performs binary classification. Our experimental dataset consists of baseline data of subjects including 186 cognitively unimpaired (CU) subjects, 336 mild cognitive impairment (MCI) subjects with 158 Late MCI and 178 Early MCI, and 146 AD patients from Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. We measured F1-measure, precision, recall, negative and positive predictive values with a 10-fold cross validation scheme. Our results indicate that our designed classifiers achieve competitive results while max pooling achieves better classification performance compared to mean-pooled features. Our deep model based research may advance FDG-PET analysis by demonstrating their potential as an effective imaging biomarker of AD.

  7. Generalization of cross-modal stimulus equivalence classes: operant processes as components in human category formation.

    PubMed Central

    Lane, S D; Clow, J K; Innis, A; Critchfield, T S

    1998-01-01

    This study employed a stimulus-class rating procedure to explore whether stimulus equivalence and stimulus generalization can combine to promote the formation of open-ended categories incorporating cross-modal stimuli. A pretest of simple auditory discrimination indicated that subjects (college students) could discriminate among a range of tones used in the main study. Before beginning the main study, 10 subjects learned to use a rating procedure for categorizing sets of stimuli as class consistent or class inconsistent. After completing conditional discrimination training with new stimuli (shapes and tones), the subjects demonstrated the formation of cross-modal equivalence classes. Subsequently, the class-inclusion rating procedure was reinstituted, this time with cross-modal sets of stimuli drawn from the equivalence classes. On some occasions, the tones of the equivalence classes were replaced by novel tones. The probability that these novel sets would be rated as class consistent was generally a function of the auditory distance between the novel tone and the tone that was explicitly included in the equivalence class. These data extend prior work on generalization of equivalence classes, and support the role of operant processes in human category formation. PMID:9821680

  8. Limits of Generalization between Categories and Implications for Theories of Category Specificity

    PubMed Central

    Bukach, Cindy M.; Phillips, W. Stewart; Gauthier, Isabel

    2010-01-01

    Both domain-specific and expertise accounts of category specialization assume that generalization occurs within a domain but not between domains. Yet it is often difficult to define the boundaries and critical features of object domains. Differences in how categories are defined make it difficult to adjudicate between accounts of category specificity and may lead to contradictory results. For example, evidence for whether car experts recruit the fusiform face area is mixed and this inconsistency may be due to the inclusion of antique cars in one of the studies. The current study tested the generalization of expertise from modern to antique cars and found that modern car experts showed expert discrimination and holistic processing of modern cars, but not antique cars. These findings suggest that the neural specialization underlying perceptual expertise is highly specific and may not generalize to distinct subclasses, even when they share some degree of perceptual and conceptual features. PMID:20952784

  9. A longitudinal study of administrative segregation.

    PubMed

    O'Keefe, Maureen L; Klebe, Kelli J; Metzner, Jeffrey; Dvoskin, Joel; Fellner, Jamie; Stucker, Alysha

    2013-01-01

    The use of administrative segregation for inmates with and without mental illness has generated considerable criticism. Segregated inmates are locked in single cells for 23 hours per day, are subjected to rigorous security procedures, and have restricted access to programs. In this study, we examined whether inmates in segregation would show greater deterioration over time on psychological symptoms than would comparison offenders. The subjects were male inmates, with and without mental illness, in administrative segregation, general population, or special-needs prison. Subjects completed the Brief Symptom Inventory at regular intervals for one year. Results showed differentiation between groups at the outset and statistically significant but small positive change over time across all groups. All groups showed the same change pattern such that there was not the hypothesized differential change of inmates within administrative segregation. This study advances the empirical research, but replication research is needed to make a better determination of whether and under what conditions harm may or may not occur to inmates in solitary confinement.

  10. Category search speeds up face-selective fMRI responses in a non-hierarchical cortical face network.

    PubMed

    Jiang, Fang; Badler, Jeremy B; Righi, Giulia; Rossion, Bruno

    2015-05-01

    The human brain is extremely efficient at detecting faces in complex visual scenes, but the spatio-temporal dynamics of this remarkable ability, and how it is influenced by category-search, remain largely unknown. In the present study, human subjects were shown gradually-emerging images of faces or cars in visual scenes, while neural activity was recorded using functional magnetic resonance imaging (fMRI). Category search was manipulated by the instruction to indicate the presence of either a face or a car, in different blocks, as soon as an exemplar of the target category was detected in the visual scene. The category selectivity of most face-selective areas was enhanced when participants were instructed to report the presence of faces in gradually decreasing noise stimuli. Conversely, the same regions showed much less selectivity when participants were instructed instead to detect cars. When "face" was the target category, the fusiform face area (FFA) showed consistently earlier differentiation of face versus car stimuli than did the "occipital face area" (OFA). When "car" was the target category, only the FFA showed differentiation of face versus car stimuli. These observations provide further challenges for hierarchical models of cortical face processing and show that during gradual revealing of information, selective category-search may decrease the required amount of information, enhancing and speeding up category-selective responses in the human brain. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Tensor functors between Morita duals of fusion categories

    NASA Astrophysics Data System (ADS)

    Galindo, César; Plavnik, Julia Yael

    2017-03-01

    Given a fusion category C and an indecomposable C -module category M , the fusion category C^*_{_{M}} of C-module endofunctors of M is called the (Morita) dual fusion category of C with respect to M . We describe tensor functors between two arbitrary duals C^*_{_{M}} and D^*_N in terms of data associated to C and D . We apply the results to G-equivariantizations of fusion categories and group-theoretical fusion categories. We describe the orbits of the action of the Brauer-Picard group on the set of module categories and we propose a categorification of the Rosenberg-Zelinsky sequence for fusion categories.

  12. Prior knowledge of category size impacts visual search.

    PubMed

    Wu, Rachel; McGee, Brianna; Echiverri, Chelsea; Zinszer, Benjamin D

    2018-03-30

    Prior research has shown that category search can be similar to one-item search (as measured by the N2pc ERP marker of attentional selection) for highly familiar, smaller categories (e.g., letters and numbers) because the finite set of items in a category can be grouped into one unit to guide search. Other studies have shown that larger, more broadly defined categories (e.g., healthy food) also can elicit N2pc components during category search, but the amplitude of these components is typically attenuated. Two experiments investigated whether the perceived size of a familiar category impacts category and exemplar search. We presented participants with 16 familiar company logos: 8 from a smaller category (social media companies) and 8 from a larger category (entertainment/recreation manufacturing companies). The ERP results from Experiment 1 revealed that, in a two-item search array, search was more efficient for the smaller category of logos compared to the larger category. In a four-item search array (Experiment 2), where two of the four items were placeholders, search was largely similar between the category types, but there was more attentional capture by nontarget members from the same category as the target for smaller rather than larger categories. These results support a growing literature on how prior knowledge of categories affects attentional selection and capture during visual search. We discuss the implications of these findings in relation to assessing cognitive abilities across the lifespan, given that prior knowledge typically increases with age. © 2018 Society for Psychophysiological Research.

  13. Recognition-induced forgetting is not due to category-based set size.

    PubMed

    Maxcey, Ashleigh M

    2016-01-01

    What are the consequences of accessing a visual long-term memory representation? Previous work has shown that accessing a long-term memory representation via retrieval improves memory for the targeted item and hurts memory for related items, a phenomenon called retrieval-induced forgetting. Recently we found a similar forgetting phenomenon with recognition of visual objects. Recognition-induced forgetting occurs when practice recognizing an object during a two-alternative forced-choice task, from a group of objects learned at the same time, leads to worse memory for objects from that group that were not practiced. An alternative explanation of this effect is that category-based set size is inducing forgetting, not recognition practice as claimed by some researchers. This alternative explanation is possible because during recognition practice subjects make old-new judgments in a two-alternative forced-choice task, and are thus exposed to more objects from practiced categories, potentially inducing forgetting due to set-size. Herein I pitted the category-based set size hypothesis against the recognition-induced forgetting hypothesis. To this end, I parametrically manipulated the amount of practice objects received in the recognition-induced forgetting paradigm. If forgetting is due to category-based set size, then the magnitude of forgetting of related objects will increase as the number of practice trials increases. If forgetting is recognition induced, the set size of exemplars from any given category should not be predictive of memory for practiced objects. Consistent with this latter hypothesis, additional practice systematically improved memory for practiced objects, but did not systematically affect forgetting of related objects. These results firmly establish that recognition practice induces forgetting of related memories. Future directions and important real-world applications of using recognition to access our visual memories of previously encountered

  14. Human Category Learning 2.0

    PubMed Central

    Ashby, F. Gregory; Maddox, W. Todd

    2010-01-01

    During the 1990’s and early 2000’s, cognitive neuroscience investigations of human category learning focused on the primary goal of showing that humans have multiple category learning systems and on the secondary goals of identifying key qualitative properties of each system and of roughly mapping out the neural networks that mediate each system. Many researchers now accept the strength of the evidence supporting multiple systems, and as a result, during the past few years, work has begun on the second generation of research questions – that is, on questions that begin with the assumption that humans have multiple category learning systems. This article reviews much of this second generation of research. Topics covered include: 1) How do the various systems interact? 2) Are there different neural systems for categorization and category representation? 3) How does automaticity develop in each system?, and 4) Exactly how does each system learn? PMID:21182535

  15. Human category learning 2.0.

    PubMed

    Ashby, F Gregory; Maddox, W Todd

    2011-04-01

    During the 1990s and early 2000s, cognitive neuroscience investigations of human category learning focused on the primary goal of showing that humans have multiple category-learning systems and on the secondary goals of identifying key qualitative properties of each system and of roughly mapping out the neural networks that mediate each system. Many researchers now accept the strength of the evidence supporting multiple systems, and as a result, during the past few years, work has begun on the second generation of research questions-that is, on questions that begin with the assumption that humans have multiple category-learning systems. This article reviews much of this second generation of research. Topics covered include (1) How do the various systems interact? (2) Are there different neural systems for categorization and category representation? (3) How does automaticity develop in each system? and (4) Exactly how does each system learn? © 2010 New York Academy of Sciences.

  16. A Probabilistic Account of Exemplar and Category Generation

    ERIC Educational Resources Information Center

    Jern, Alan; Kemp, Charles

    2013-01-01

    People are capable of imagining and generating new category exemplars and categories. This ability has not been addressed by previous models of categorization, most of which focus on classifying category exemplars rather than generating them. We develop a formal account of exemplar and category generation which proposes that category knowledge is…

  17. 1 CFR 6.2 - Analytical subject indexes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Analytical subject indexes. 6.2 Section 6.2 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.2 Analytical subject indexes. Analytical subject indexes covering the contents of the Federal...

  18. 1 CFR 6.2 - Analytical subject indexes.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Analytical subject indexes. 6.2 Section 6.2 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.2 Analytical subject indexes. Analytical subject indexes covering the contents of the Federal...

  19. 1 CFR 6.2 - Analytical subject indexes.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Analytical subject indexes. 6.2 Section 6.2 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.2 Analytical subject indexes. Analytical subject indexes covering the contents of the Federal...

  20. 1 CFR 6.2 - Analytical subject indexes.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Analytical subject indexes. 6.2 Section 6.2 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.2 Analytical subject indexes. Analytical subject indexes covering the contents of the Federal...

  1. 1 CFR 6.2 - Analytical subject indexes.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Analytical subject indexes. 6.2 Section 6.2 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.2 Analytical subject indexes. Analytical subject indexes covering the contents of the Federal...

  2. Shifting categories of the social harms associated with alcohol: examples from late medieval and early modern England.

    PubMed Central

    Warner, J

    1997-01-01

    This paper offers a historical perspective on our own attempts to define the social harms associated with the abuse of alcohol. Challenging the notion that categories are necessarily objective and constant, it instead emphasizes the extent to which even harms that are visible and thus susceptible to measurement are in fact socially constructed. English sources from the preindustrial era revealed six broad categories of social harms associated with the abuse of alcohol. Four of the categories consisted of visible harms in the form of income lost, domestic violence, brawling, and accidents, all of which are still recognized as social harms associated with the abuse of alcohol. The other two categories, reversal of the established moral order and susceptibility to trickery, were of an essentially intrinsic or subjective nature and have since dropped from the lexicon of social harms. Images FIGURE 1 FIGURE 3 PMID:9366636

  3. 40 CFR 1042.101 - Exhaust emission standards for Category 1 engines and Category 2 engines.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... from research engines or similar engine models that are already in production. Your demonstration must... Category 1 engines and Category 2 engines. 1042.101 Section 1042.101 Protection of Environment... MARINE COMPRESSION-IGNITION ENGINES AND VESSELS Emission Standards and Related Requirements § 1042.101...

  4. Reconceptualizing 'extremism' and 'moderation': from categories of analysis to categories of practice in the construction of collective identity.

    PubMed

    Hopkins, Nick; Kahani-Hopkins, Vered

    2009-03-01

    Much psychological research employs the categories of extremism and moderation as categories of analysis (e.g. to identify the psychological bases for, and consequences of, holding certain positions). This paper argues these categorizations inevitably reflect one's values and taken-for-granted assumptions about social reality and that their use as analytic categories limits our ability to explore what is really important: social actors' own constructions of social reality. In turn we argue that if we are to focus on this latter, there may be merit in exploring how social actors themselves use the categories of moderation and extremism to construct their own terms of reference. That is we propose to re-conceptualize the categories of moderation and extremism as categories of practice rather than analysis. The utility of this approach is illustrated with qualitative data. We argue that these data illustrate the importance of respecting social actors' own constructions of social reality (rather than imposing our own). Moreover, we argue that categories of moderation and extremism may be employed by social actors in diverse ways to construct different terms of reference and so recruit support for different identity-related projects.

  5. Development of visual category selectivity in ventral visual cortex does not require visual experience

    PubMed Central

    van den Hurk, Job; Van Baelen, Marc; Op de Beeck, Hans P.

    2017-01-01

    To what extent does functional brain organization rely on sensory input? Here, we show that for the penultimate visual-processing region, ventral-temporal cortex (VTC), visual experience is not the origin of its fundamental organizational property, category selectivity. In the fMRI study reported here, we presented 14 congenitally blind participants with face-, body-, scene-, and object-related natural sounds and presented 20 healthy controls with both auditory and visual stimuli from these categories. Using macroanatomical alignment, response mapping, and surface-based multivoxel pattern analysis, we demonstrated that VTC in blind individuals shows robust discriminatory responses elicited by the four categories and that these patterns of activity in blind subjects could successfully predict the visual categories in sighted controls. These findings were confirmed in a subset of blind participants born without eyes and thus deprived from all light perception since conception. The sounds also could be decoded in primary visual and primary auditory cortex, but these regions did not sustain generalization across modalities. Surprisingly, although not as strong as visual responses, selectivity for auditory stimulation in visual cortex was stronger in blind individuals than in controls. The opposite was observed in primary auditory cortex. Overall, we demonstrated a striking similarity in the cortical response layout of VTC in blind individuals and sighted controls, demonstrating that the overall category-selective map in extrastriate cortex develops independently from visual experience. PMID:28507127

  6. 28 CFR 8.5 - Appraisement of property subject to forfeiture.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Appraisement of property subject to forfeiture. 8.5 Section 8.5 Judicial Administration DEPARTMENT OF JUSTICE FBI FORFEITURE AUTHORITY FOR CERTAIN STATUTES § 8.5 Appraisement of property subject to forfeiture. Seized property shall be appraised...

  7. 28 CFR 8.5 - Appraisement of property subject to forfeiture.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Appraisement of property subject to forfeiture. 8.5 Section 8.5 Judicial Administration DEPARTMENT OF JUSTICE FBI FORFEITURE AUTHORITY FOR CERTAIN STATUTES § 8.5 Appraisement of property subject to forfeiture. Seized property shall be appraised...

  8. 28 CFR 8.5 - Appraisement of property subject to forfeiture.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Appraisement of property subject to forfeiture. 8.5 Section 8.5 Judicial Administration DEPARTMENT OF JUSTICE FBI FORFEITURE AUTHORITY FOR CERTAIN STATUTES § 8.5 Appraisement of property subject to forfeiture. Seized property shall be appraised...

  9. Educational Administration's Weber.

    ERIC Educational Resources Information Center

    Gronn, Peter

    1994-01-01

    Discusses Max Weber's importance in Greenfield's work, particularly in Greenfield and Ribbins'"Greenfield on Educational Administration" (1993). In concentrating on human actors' subjective understanding, Greenfield was a faithful Weberian. However, he deviated from Weber by disavowing structural explanations of social and organizational…

  10. Category Rating Is Based on Prototypes and Not Instances: Evidence from Feedback-Dependent Context Effects

    ERIC Educational Resources Information Center

    Petrov, Alexander A.

    2011-01-01

    Context effects in category rating on a 7-point scale are shown to reverse direction depending on feedback. Context (skewed stimulus frequencies) was manipulated between and feedback within subjects in two experiments. The diverging predictions of prototype- and exemplar-based scaling theories were tested using two representative models: ANCHOR…

  11. 40 CFR 1042.101 - Exhaust emission standards for Category 1 engines and Category 2 engines.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... information equivalent to such in-use data, such as data from research engines or similar engine models that... Category 1 engines and Category 2 engines. 1042.101 Section 1042.101 Protection of Environment... MARINE COMPRESSION-IGNITION ENGINES AND VESSELS Emission Standards and Related Requirements § 1042.101...

  12. 40 CFR 1042.101 - Exhaust emission standards for Category 1 engines and Category 2 engines.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... information equivalent to such in-use data, such as data from research engines or similar engine models that... Category 1 engines and Category 2 engines. 1042.101 Section 1042.101 Protection of Environment... MARINE COMPRESSION-IGNITION ENGINES AND VESSELS Emission Standards and Related Requirements § 1042.101...

  13. 40 CFR 1042.101 - Exhaust emission standards for Category 1 engines and Category 2 engines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... information equivalent to such in-use data, such as data from research engines or similar engine models that... Category 1 engines and Category 2 engines. 1042.101 Section 1042.101 Protection of Environment... MARINE COMPRESSION-IGNITION ENGINES AND VESSELS Emission Standards and Related Requirements § 1042.101...

  14. Self-administration of intranasal influenza vaccine: Immunogenicity and volunteer acceptance

    PubMed Central

    Burgess, Timothy H.; Murray, Clinton K.; Bavaro, Mary F.; Landrum, Michael L.; O’Bryan, Thomas A.; Rosas, Jessica G.; Cammarata, Stephanie M.; Martin, Nicholas J.; Ewing, Daniel; Raviprakash, Kanakatte; Mor, Deepika; Zell, Elizabeth R.; Wilkins, Kenneth J.; Millar, Eugene V.

    2018-01-01

    Background In outbreak settings, mass vaccination strategies could maximize health protection of military personnel. Self-administration of live attenuated influenza vaccine (LAIV) may be a means to vaccinate large numbers of people and achieve deployment readiness while sparing the use of human resources. Methods A phase IV, open-label, randomized controlled trial evaluating the immunogenicity and acceptance of self-administered (SA) LAIV was conducted from 2012 to 2014. SA subjects were randomized to either individual self-administration or self-administration in a group setting. Control randomized subjects received healthcare worker-administered (HCWA) LAIV. Anti-hemagglutinin (HAI) antibody concentrations were measured pre- and post-vaccination. The primary endpoint was immunogenicity non-inferiority between SA and HCWA groups. Subjects were surveyed on preferred administration method. Results A total of 1077 subjects consented and were randomized (529 SA, 548 HCWA). Subject characteristics were very similar between groups, though SA subjects were younger, more likely to be white and on active duty. The per-protocol analysis included 1024 subjects (501 SA, 523 HCWA). Post-vaccination geometric mean titers by vaccine strain and by study group (HCWA vs. SA) were: A/H1N1 (45.8 vs. 48.7, respectively; p = 0.43), A/H3N2 (45.5 vs. 46.4; p = 0.80), B/Yamagata (17.2 vs. 17.8; p = 0.55). Seroresponses to A components were high (∼67%), while seroresponses to B components were lower (∼25%). Seroresponse did not differ by administration method. Baseline preference for administration method was similar between groups, with the majority in each group expressing no preference. At follow-up, the majority (64%) of SA subjects preferred SA vaccine. Conclusions LAIV immunogenicity was similar for HCWA and SA vaccines. SA was well-tolerated and preferred to HCWA among those who performed SA. PMID:26117150

  15. Neuronal correlates of reduced memory performance in overweight subjects.

    PubMed

    Stingl, Krunoslav T; Kullmann, Stephanie; Ketterer, Caroline; Heni, Martin; Häring, Hans-Ulrich; Fritsche, Andreas; Preissl, Hubert

    2012-03-01

    There is growing evidence that excessive body weight correlates with impaired cognitive performance like executive function, attention and memory. In our study, we applied a visual working memory task to quantify associations between body weight and executive function. In total, 34 lean (BMI 22±2.1 kg/m(2)) and 34 obese (BMI 30.4±3.2 kg/m(2)) subjects were included. Magnetic brain activity and behavioral responses were recorded during a one-back visual memory task with food and non-food pictures, which were matched for color, size and complexity. Behavioral responses (reaction time and accuracy) were reduced in obese subjects independent of the stimulus category. Neuronal activity at the source level showed a positive correlation between the right dorsolateral prefrontal cortex (DLPFC) activity and BMI only for the food category. In addition, a negative correlation between BMI and neuronal activity was observed in the occipital area for both categories. Therefore we conclude that increased body weight is associated with reduced task performance and specific neuronal changes. This altered activity is probably related to executive function as well as encoding and retrieval of information. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Dual-learning systems during speech category learning

    PubMed Central

    Chandrasekaran, Bharath; Yi, Han-Gyol; Maddox, W. Todd

    2013-01-01

    Dual-systems models of visual category learning posit the existence of an explicit, hypothesis-testing ‘reflective’ system, as well as an implicit, procedural-based ‘reflexive’ system. The reflective and reflexive learning systems are competitive and neurally dissociable. Relatively little is known about the role of these domain-general learning systems in speech category learning. Given the multidimensional, redundant, and variable nature of acoustic cues in speech categories, our working hypothesis is that speech categories are learned reflexively. To this end, we examined the relative contribution of these learning systems to speech learning in adults. Native English speakers learned to categorize Mandarin tone categories over 480 trials. The training protocol involved trial-by-trial feedback and multiple talkers. Experiment 1 and 2 examined the effect of manipulating the timing (immediate vs. delayed) and information content (full vs. minimal) of feedback. Dual-systems models of visual category learning predict that delayed feedback and providing rich, informational feedback enhance reflective learning, while immediate and minimally informative feedback enhance reflexive learning. Across the two experiments, our results show feedback manipulations that targeted reflexive learning enhanced category learning success. In Experiment 3, we examined the role of trial-to-trial talker information (mixed vs. blocked presentation) on speech category learning success. We hypothesized that the mixed condition would enhance reflexive learning by not allowing an association between talker-related acoustic cues and speech categories. Our results show that the mixed talker condition led to relatively greater accuracies. Our experiments demonstrate that speech categories are optimally learned by training methods that target the reflexive learning system. PMID:24002965

  17. Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses.

    PubMed

    Bouhlal, Sofia; Ellefsen, Kayla N; Sheskier, Mikela B; Singley, Erick; Pirard, Sandrine; Gorelick, David A; Huestis, Marilyn A; Leggio, Lorenzo

    2017-11-01

    Food intake and use of drugs of abuse like cocaine share common central and peripheral physiological pathways. Appetitive hormones play a major role in regulating food intake; however, little is known about the effects of acute cocaine administration on the blood concentrations of these hormones in cocaine users. We evaluated serum concentrations of six appetitive hormones: ghrelin (total and acyl-ghrelin), amylin, glucagon-like peptide-1 (GLP-1), insulin, leptin and peptide YY (PYY), as well as acute cardiorespiratory and subjective responses of 8 experienced cocaine users who received 25mg intravenous (IV) cocaine. Serum concentrations of GLP-1 (p=0.014) and PYY (p=0.036) were significantly decreased one hour following IV cocaine administration; there was a trend towards a decrease for insulin (p=0.055) and amylin (p=0.063) concentrations, while no significant IV cocaine effect was observed for ghrelin (total or acyl-ghrelin) or leptin concentrations (p's≫>0.5). We also observed associations between hormone concentrations acutely affected by IV cocaine (GLP-1, PYY, insulin, amylin) and some cocaine-related cardiorespiratory and subjective responses (e.g., increased heart and respiratory rates; feeling high and anxious). These findings show a significant effect of acute IV cocaine administration on some appetitive hormones and suggest potential associations between these hormones and cocaine-related cardiorespiratory and subjective responses. Additional research is needed to further investigate the potential mechanisms underlining these associations. Published by Elsevier B.V.

  18. Effects of Category-Specific Costs on Neural Systems for Perceptual Decision-Making

    PubMed Central

    Whiteley, Louise; Hulme, Oliver J.; Sahani, Maneesh; Dolan, Raymond J.

    2010-01-01

    Perceptual judgments are often biased by prospective losses, leading to changes in decision criteria. Little is known about how and where sensory evidence and cost information interact in the brain to influence perceptual categorization. Here we show that prospective losses systematically bias the perception of noisy face-house images. Asymmetries in category-specific cost were associated with enhanced blood-oxygen-level-dependent signal in a frontoparietal network. We observed selective activation of parahippocampal gyrus for changes in category-specific cost in keeping with the hypothesis that loss functions enact a particular task set that is communicated to visual regions. Across subjects, greater shifts in decision criteria were associated with greater activation of the anterior cingulate cortex (ACC). Our results support a hypothesis that costs bias an intermediate representation between perception and action, expressed via general effects on frontal cortex, and selective effects on extrastriate cortex. These findings indicate that asymmetric costs may affect a neural implementation of perceptual decision making in a similar manner to changes in category expectation, constituting a step toward accounting for how prospective losses are flexibly integrated with sensory evidence in the brain. PMID:20357071

  19. Effects of category-specific costs on neural systems for perceptual decision-making.

    PubMed

    Fleming, Stephen M; Whiteley, Louise; Hulme, Oliver J; Sahani, Maneesh; Dolan, Raymond J

    2010-06-01

    Perceptual judgments are often biased by prospective losses, leading to changes in decision criteria. Little is known about how and where sensory evidence and cost information interact in the brain to influence perceptual categorization. Here we show that prospective losses systematically bias the perception of noisy face-house images. Asymmetries in category-specific cost were associated with enhanced blood-oxygen-level-dependent signal in a frontoparietal network. We observed selective activation of parahippocampal gyrus for changes in category-specific cost in keeping with the hypothesis that loss functions enact a particular task set that is communicated to visual regions. Across subjects, greater shifts in decision criteria were associated with greater activation of the anterior cingulate cortex (ACC). Our results support a hypothesis that costs bias an intermediate representation between perception and action, expressed via general effects on frontal cortex, and selective effects on extrastriate cortex. These findings indicate that asymmetric costs may affect a neural implementation of perceptual decision making in a similar manner to changes in category expectation, constituting a step toward accounting for how prospective losses are flexibly integrated with sensory evidence in the brain.

  20. Queer and Trans Youth, Relational Subjectivity, and Uncertain Possibilities: Challenging Research in Complicated Contexts

    ERIC Educational Resources Information Center

    Mayo, Cris

    2017-01-01

    This article addresses complications to how different disciplines define, study, and theorize sexuality, gender, gender identity, and other intersecting categories of subjectivity, like age, race, class, ethnicity, and so on. Categories that seem to get stabilized in empirical work are destabilized in theoretical and narrative research. These…

  1. Category Label Effects on Chinese Children's Inductive Inferences: Modulation by Perceptual Detail and Category Specificity

    ERIC Educational Resources Information Center

    Long, Changquan; Lu, Xiaoying; Zhang, Li; Li, Hong; Deak, Gedeon O.

    2012-01-01

    Inductive generalization of novel properties to same-category or similar-looking objects was studied in Chinese preschool children. The effects of category labels on generalizations were investigated by comparing basic-level labels, superordinate-level labels, and a control phrase applied to three kinds of stimulus materials: colored photographs…

  2. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  3. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  4. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  5. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 2 2013-04-01 2013-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  6. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 2 2014-04-01 2014-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  7. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 2 2011-04-01 2011-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  8. 19 CFR 174.11 - Matters subject to protest.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 2 2012-04-01 2012-04-01 false Matters subject to protest. 174.11 Section 174.11... TREASURY (CONTINUED) PROTESTS Protests § 174.11 Matters subject to protest. The following decisions of CBP... administrative decisions involving the following subject matters are subject to protest: (1) The appraised value...

  9. Subject Choice and Earnings of UK Graduates

    ERIC Educational Resources Information Center

    Chevalier, Arnaud

    2011-01-01

    Using a survey of a cohort of UK graduates, linked to administrative data on higher education participation, this paper investigates the labour market attainment of recent graduates by subject of study. We document a large heterogeneity in the mean wages of graduates from different subjects and a considerably larger one within subject with…

  10. Perceptual and category processing of the Uncanny Valley hypothesis' dimension of human likeness: some methodological issues.

    PubMed

    Cheetham, Marcus; Jancke, Lutz

    2013-06-03

    Mori's Uncanny Valley Hypothesis(1,2) proposes that the perception of humanlike characters such as robots and, by extension, avatars (computer-generated characters) can evoke negative or positive affect (valence) depending on the object's degree of visual and behavioral realism along a dimension of human likeness (DHL) (Figure 1). But studies of affective valence of subjective responses to variously realistic non-human characters have produced inconsistent findings (3, 4, 5, 6). One of a number of reasons for this is that human likeness is not perceived as the hypothesis assumes. While the DHL can be defined following Mori's description as a smooth linear change in the degree of physical humanlike similarity, subjective perception of objects along the DHL can be understood in terms of the psychological effects of categorical perception (CP) (7). Further behavioral and neuroimaging investigations of category processing and CP along the DHL and of the potential influence of the dimension's underlying category structure on affective experience are needed. This protocol therefore focuses on the DHL and allows examination of CP. Based on the protocol presented in the video as an example, issues surrounding the methodology in the protocol and the use in "uncanny" research of stimuli drawn from morph continua to represent the DHL are discussed in the article that accompanies the video. The use of neuroimaging and morph stimuli to represent the DHL in order to disentangle brain regions neurally responsive to physical human-like similarity from those responsive to category change and category processing is briefly illustrated.

  11. Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

    PubMed Central

    Cheetham, Marcus; Jancke, Lutz

    2013-01-01

    Mori's Uncanny Valley Hypothesis1,2 proposes that the perception of humanlike characters such as robots and, by extension, avatars (computer-generated characters) can evoke negative or positive affect (valence) depending on the object's degree of visual and behavioral realism along a dimension of human likeness (DHL) (Figure 1). But studies of affective valence of subjective responses to variously realistic non-human characters have produced inconsistent findings 3, 4, 5, 6. One of a number of reasons for this is that human likeness is not perceived as the hypothesis assumes. While the DHL can be defined following Mori's description as a smooth linear change in the degree of physical humanlike similarity, subjective perception of objects along the DHL can be understood in terms of the psychological effects of categorical perception (CP) 7. Further behavioral and neuroimaging investigations of category processing and CP along the DHL and of the potential influence of the dimension's underlying category structure on affective experience are needed. This protocol therefore focuses on the DHL and allows examination of CP. Based on the protocol presented in the video as an example, issues surrounding the methodology in the protocol and the use in "uncanny" research of stimuli drawn from morph continua to represent the DHL are discussed in the article that accompanies the video. The use of neuroimaging and morph stimuli to represent the DHL in order to disentangle brain regions neurally responsive to physical human-like similarity from those responsive to category change and category processing is briefly illustrated. PMID:23770728

  12. 15 CFR 904.273 - Administrative review of decision.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures Decision § 904.273 Administrative review of decision. (a) Subject to...

  13. 40 CFR 156.62 - Toxicity Category.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... being the highest toxicity category. Most human hazard, precautionary statements, and human personal protective equipment statements are based upon the Toxicity Category of the pesticide product as sold or...

  14. 40 CFR 156.62 - Toxicity Category.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... being the highest toxicity category. Most human hazard, precautionary statements, and human personal protective equipment statements are based upon the Toxicity Category of the pesticide product as sold or...

  15. Using contingent valuation to value a noxious weeds control program: the effects of including an unsure response category

    Treesearch

    Patricia A. Champ; Anna Alberini; Ignacio Correas

    2005-01-01

    The National Oceanic and Atmospheric Administration Contingent Valuation panel recommended that a response category be included along with the vote in favor and vote against options associated with a referendum contingent valuation question that allows individuals to express lack of a well defined opinion. However, the recommendation did not include guidance on how to...

  16. Hippocampal activation during episodic and semantic memory retrieval: comparing category production and category cued recall.

    PubMed

    Ryan, Lee; Cox, Christine; Hayes, Scott M; Nadel, Lynn

    2008-01-01

    Whether or not the hippocampus participates in semantic memory retrieval has been the focus of much debate in the literature. However, few neuroimaging studies have directly compared hippocampal activation during semantic and episodic retrieval tasks that are well matched in all respects other than the source of the retrieved information. In Experiment 1, we compared hippocampal fMRI activation during a classic semantic memory task, category production, and an episodic version of the same task, category cued recall. Left hippocampal activation was observed in both episodic and semantic conditions, although other regions of the brain clearly distinguished the two tasks. Interestingly, participants reported using retrieval strategies during the semantic retrieval task that relied on autobiographical and spatial information; for example, visualizing themselves in their kitchen while producing items for the category kitchen utensils. In Experiment 2, we considered whether the use of these spatial and autobiographical retrieval strategies could have accounted for the hippocampal activation observed in Experiment 1. Categories were presented that elicited one of three retrieval strategy types, autobiographical and spatial, autobiographical and nonspatial, and neither autobiographical nor spatial. Once again, similar hippocampal activation was observed for all three category types, regardless of the inclusion of spatial or autobiographical content. We conclude that the distinction between semantic and episodic memory is more complex than classic memory models suggest.

  17. Hippocampal Activation during Episodic and Semantic Memory Retrieval: Comparing Category Production and Category Cued Recall

    PubMed Central

    Ryan, Lee; Cox, Christine; Hayes, Scott M.; Nadel, Lynn

    2008-01-01

    Whether or not the hippocampus participates in semantic memory retrieval has been the focus of much debate in the literature. However, few neuroimaging studies have directly compared hippocampal activation during semantic and episodic retrieval tasks that are well matched in all respects other than the source of the retrieved information. In Experiment 1, we compared hippocampal fMRI activation during a classic semantic memory task, category production, and an episodic version of the same task, category cued recall. Left hippocampal activation was observed in both episodic and semantic conditions, although other regions of the brain clearly distinguished the two tasks. Interestingly, participants reported using retrieval strategies during the semantic retrieval task that relied on autobiographical and spatial information; for example, visualizing themselves in their kitchen while producing items for the category kitchen utensils. In Experiment 2, we considered whether the use of these spatial and autobiographical retrieval strategies could have accounted for the hippocampal activation observed in Experiment 1. Categories were presented that elicited one of three retrieval strategy types, autobiographical and spatial, autobiographical and nonspatial, and neither autobiographical nor spatial. Once again, similar hippocampal activation was observed for all three category types, regardless of the inclusion of spatial or autobiographical content. We conclude that the distinction between semantic and episodic memory is more complex than classic memory models suggest. PMID:18420234

  18. 29 CFR 6.6 - Administrative Law Judge.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Administrative Law Judge. 6.6 Section 6.6 Labor Office of... Administrative Law Judge. (a) Equal Access to Justice Act. Proceedings under this part are not subject to the... provisions of this part 6, Administrative Law Judges shall have no power or authority to award attorney fees...

  19. Subjective scaling of hand-arm vibration.

    PubMed

    Maeda, Setsuo; Shibata, Nobuyuki

    2008-04-01

    The purpose of this research was to establish a scale for comfort with regard to hand-arm vibration using the category judgment method and to validate the frequency-weighting method of the ISO 5349-1 standard. Experiments were conducted using random signals as stimuli. These stimuli consisted of three types of signal, namely designated stimulus F, with flat power spectrum density (PSD) ranging from 1 to 1,000 Hz, stimulus H with PSD which became 20 dB higher at 1,000 Hz than at 1 Hz, and stimulus L that had a PSD 20 dB lower at 1,000 Hz. These stimuli were selected from the specific spectrum patterns of hand-held vibration tools. These signals were modified by the Wh frequency weighting in accordance with ISO 5349-1, and the R.M.S. values were adjusted to be equal. In addition, the signal levels were varied over a range of five steps to create 15 kinds of individual stimuli. The subjects sat in front of a vibrator and grasped the mounted handle which exposed them to vertical vibrations after which they were asked to choose a numerical category to best indicate their perceived level of comfort (or otherwise) during each stimulus. From the experimental results of the category judgment method, the relationship between the psychological values and the frequency-weighted R.M.S. acceleration according to the ISO 5349-1 standard was obtained. It was found that the subjective response scaling of hand-arm vibration can be used for design-objective values of hand-held tool vibration.

  20. An Analysis of Document Category Prediction Responses to Classifier Model Parameter Treatment Permutations within the Software Design Patterns Subject Domain

    ERIC Educational Resources Information Center

    Pankau, Brian L.

    2009-01-01

    This empirical study evaluates the document category prediction effectiveness of Naive Bayes (NB) and K-Nearest Neighbor (KNN) classifier treatments built from different feature selection and machine learning settings and trained and tested against textual corpora of 2300 Gang-Of-Four (GOF) design pattern documents. Analysis of the experiment's…

  1. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Land category assignments...

  2. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Land category assignments...

  3. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Land category assignments...

  4. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Land category assignments...

  5. 14 CFR 29.85 - Balked landing: Category A.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Balked landing: Category A. 29.85 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.85 Balked landing: Category A. For Category A rotorcraft, the balked landing path with the critical engine inoperative must be...

  6. 14 CFR 29.85 - Balked landing: Category A.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Balked landing: Category A. 29.85 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.85 Balked landing: Category A. For Category A rotorcraft, the balked landing path with the critical engine inoperative must be...

  7. Supervised and Unsupervised Learning of Multidimensional Acoustic Categories

    ERIC Educational Resources Information Center

    Goudbeek, Martijn; Swingley, Daniel; Smits, Roel

    2009-01-01

    Learning to recognize the contrasts of a language-specific phonemic repertoire can be viewed as forming categories in a multidimensional psychophysical space. Research on the learning of distributionally defined visual categories has shown that categories defined over 1 dimension are easy to learn and that learning multidimensional categories is…

  8. Age-related differences in the neural basis of the subjective vividness of memories: Evidence from multivoxel pattern classification

    PubMed Central

    Johnson, Marcia K.; Kuhl, Brice A.; Mitchell, Karen J.; Ankudowich, Elizabeth; Durbin, Kelly A.

    2016-01-01

    Although older adults often show reduced episodic memory accuracy, their ratings of the subjective vividness of their memories often equal or even exceed those of young adults. Such findings suggest that young and older adults may differentially access and/or weight different kinds of information in making vividness judgments. We examined this idea using multivoxel pattern classification of fMRI data to measure category representations while participants saw and remembered pictures of objects and scenes. Consistent with our hypothesis, there were age-related differences in how category representations related to the subjective sense of vividness. During remembering, older adults’ vividness ratings were more related, relative to young adults’, to category representations in prefrontal cortex. In contrast, young adults’ vividness ratings were more related, relative to older adults, to category representations in parietal cortex. In addition, category representations were more correlated among posterior regions in young than older adults, whereas correlations between PFC and posterior regions did not differ between the two groups. Together, these results are consistent with the idea that young and older adults differentially weight different types of information in assessing subjective vividness of their memories. PMID:25855004

  9. Eyetracking Reveals Multiple-Category Use in Induction

    ERIC Educational Resources Information Center

    Chen, Stephanie Y.; Ross, Brian H.; Murphy, Gregory L.

    2016-01-01

    Category information is used to predict properties of new category members. When categorization is uncertain, people often rely on only one, most likely category to make predictions. Yet studies of perception and action often conclude that people combine multiple sources of information near-optimally. We present a perception-action analog of…

  10. 21 CFR 20.108 - Agreements between the Food and Drug Administration and other departments, agencies, and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Specific Categories of Records § 20.108 Agreements between the Food and Drug Administration and other... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Agreements between the Food and Drug Administration and other departments, agencies, and organizations. 20.108 Section 20.108 Food and Drugs FOOD AND...

  11. Catecholaminergic, neuroendocrine and anxiety responses to acute psychological stress in healthy subjects: influence of alprazolam administration.

    PubMed

    Santagostino, G; Amoretti, G; Frattini, P; Zerbi, F; Cucchi, M L; Preda, S; Corona, G L

    1996-01-01

    We studied the effect of alprazolam (APZ) in 12 healthy volunteers on the psychological stress-induced activation of emotion and on the pituitary-adrenal, adrenomedullary and sympathoneuronal systems. After 3 days of placebo or APZ (1 mg/day orally) administration, we examined plasma levels of adrenocorticotropic hormone, cortisol, L-3,4 dihydroxyphenylalanine, dopamine, norepinephrine (NE), epinephrine, metanephrine, normetanephrine, homovanillic acid, vanillylmandelic acid, 3-methoxy-4-hydroxy phenyglycol, urinary levels of cortisol and catecholamines, circulatory responses and state anxiety levels in subjects undergoing psychological stress based on viewing horror, violence, danger and war film clips. Film viewing produced modest rises of state anxiety levels, of plasma NE concentration and of diastolic blood pressure in both the placebo and drug groups. APZ significantly reduced anxiety levels at the beginning of the experimental session and caused a decrease of noradrenergic and dopaminergic neurotransmitter and cortisol concentrations. Our data suggest that APZ reduced anxiety related to the expectation of the event, while the circuitry between structures responsible for anxiety and peripheral sympathoneural function was still found to be partly sensitive to film viewing.

  12. Racialized Subjects in a Colour Blind School

    ERIC Educational Resources Information Center

    Lagermann, Laila Colding

    2013-01-01

    In this paper I examine processes of racialization in a school in Copenhagen, Denmark. On the basis of the data produced in 2009, which is part of a larger study, I investigate themes of race as a difference-making and constituting category for subjective (human) becoming and racialization as contingent and negotiated processes (Butler, 1997). As…

  13. Development of a category 2 approach system model

    NASA Technical Reports Server (NTRS)

    Johnson, W. A.; Mcruer, D. T.

    1972-01-01

    An analytical model is presented which provides, as its primary output, the probability of a successful Category II approach. Typical applications are included using several example systems (manual and automatic) which are subjected to random gusts and deterministic wind shear. The primary purpose of the approach system model is to establish a structure containing the system elements, command inputs, disturbances, and their interactions in an analytical framework so that the relative effects of changes in the various system elements on precision of control and available margins of safety can be estimated. The model is intended to provide insight for the design and integration of suitable autopilot, display, and navigation elements; and to assess the interaction of such elements with the pilot/copilot.

  14. 29 CFR 4044.14 - Priority category 4 benefits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... priority category 4 with respect to a participant is not limited by the aggregate benefits limitations set... 29 Labor 9 2010-07-01 2010-07-01 false Priority category 4 benefits. 4044.14 Section 4044.14 Labor... Priority category 4 benefits. The benefits assigned to priority category 4 with respect to each participant...

  15. 14 CFR 29.83 - Landing: Category B.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Landing: Category B. 29.83 Section 29.83... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.83 Landing: Category B. (a) For each... of approximately 3 knots for water landings) from a point 50 feet above the landing surface must be...

  16. Incremental Bayesian Category Learning from Natural Language

    ERIC Educational Resources Information Center

    Frermann, Lea; Lapata, Mirella

    2016-01-01

    Models of category learning have been extensively studied in cognitive science and primarily tested on perceptual abstractions or artificial stimuli. In this paper, we focus on categories acquired from natural language stimuli, that is, words (e.g., "chair" is a member of the furniture category). We present a Bayesian model that, unlike…

  17. Differences in plasma apelin and visfatin levels between patients with type 1 diabetes mellitus and healthy subjects and response after acute hyperglycemia and insulin administration.

    PubMed

    Alexiadou, Kleopatra; Kokkinos, Alexander; Liatis, Stavros; Perrea, Despoina; Katsilambros, Nicholas; Tentolouris, Nicholas

    2012-01-01

    Previous data suggest that apelin and visfatin play a role in metabolism and glucose homeostasis. The aim of the present study was to determine differences in plasma apelin and visfatin concentrations between healthy subjects and patients with type 1 diabetes mellitus and to study the effect of hyperglycemia and insulin administration on their levels in patients with type 1 diabetes mellitus. One hundred patients with T1DM and 52 healthy subjects were examined. Nine patients with type 1 diabetes and 9 controls participated in a further study. In the main study, blood samples were taken after a 12-hour fast. In a further study, an oral glucose tolerance test was performed on two occasions. In session A, at baseline, insulin lispro (7 units) was administered subcutaneously to the type 1 diabetic patients, while a placebo injection was administered to controls. In session B, no insulin or placebo was administered. Apelin, visfatin, insulin and glucose levels were measured at baseline and 10, 20, 30, 60, 90, 120, 150 and 180 min after glucose consumption. Fasting plasma apelin concentrations were higher (p<0.001), while fasting visfatin levels tended to be lower (p=0.06) in patients with type 1 diabetes in comparison to healthy subjects. In the diabetes group, fasting apelin (but not visfatin) correlated with HDL-C (p=0.001). Apelin and visfatin did not change significantly during the oral glucose tolerance test in either group with or without exogenous insulin administration.

  18. Identification of prelinguistic phonological categories.

    PubMed

    Ramsdell, Heather L; Oller, D Kimbrough; Buder, Eugene H; Ethington, Corinna A; Chorna, Lesya

    2012-12-01

    The prelinguistic infant's babbling repertoire of syllables--the phonological categories that form the basis for early word learning--is noticed by caregivers who interact with infants around them. Prior research on babbling has not explored the caregiver's role in recognition of early vocal categories as foundations for word learning. In the present work, the authors begin to address this gap. The authors explored vocalizations produced by 8 infants at 3 ages (8, 10, and 12 months) in studies illustrating identification of phonological categories through caregiver report, laboratory procedures simulating the caregiver's natural mode of listening, and the more traditional laboratory approach (phonetic transcription). Caregivers reported small repertoires of syllables for their infants. Repertoires of similar size and phonetic content were discerned in the laboratory by judges who simulated the caregiver's natural mode of listening. However, phonetic transcription with repeated listening to infant recordings yielded repertoire sizes that vastly exceeded those reported by caregivers and naturalistic listeners. The results suggest that caregiver report and naturalistic listening by laboratory staff can provide a new way to explore key characteristics of early infant vocal categories, a way that may provide insight into later speech and language development.

  19. 75 FR 40756 - Implementation Guidance for Physical Protection of Byproduct Material; Category 1 and Category 2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ...-2010-0194] RIN 3150-AI12 Implementation Guidance for Physical Protection of Byproduct Material... licensee or applicant for implementation of proposed 10 CFR part 37, ``Physical Protection of Byproduct... ``Implementation Guidance for 10 CFR part 37 Physical Protection of Byproduct Material, Category 1 and Category 2...

  20. SUSTAIN: a network model of category learning.

    PubMed

    Love, Bradley C; Medin, Douglas L; Gureckis, Todd M

    2004-04-01

    SUSTAIN (Supervised and Unsupervised STratified Adaptive Incremental Network) is a model of how humans learn categories from examples. SUSTAIN initially assumes a simple category structure. If simple solutions prove inadequate and SUSTAIN is confronted with a surprising event (e.g., it is told that a bat is a mammal instead of a bird), SUSTAIN recruits an additional cluster to represent the surprising event. Newly recruited clusters are available to explain future events and can themselves evolve into prototypes-attractors-rules. SUSTAIN's discovery of category substructure is affected not only by the structure of the world but by the nature of the learning task and the learner's goals. SUSTAIN successfully extends category learning models to studies of inference learning, unsupervised learning, category construction, and contexts in which identification learning is faster than classification learning.

  1. Optical identification of subjects at high risk for developing breast cancer

    NASA Astrophysics Data System (ADS)

    Taroni, Paola; Quarto, Giovanna; Pifferi, Antonio; Ieva, Francesca; Paganoni, Anna Maria; Abbate, Francesca; Balestreri, Nicola; Menna, Simona; Cassano, Enrico; Cubeddu, Rinaldo

    2013-06-01

    A time-domain multiwavelength (635 to 1060 nm) optical mammography was performed on 147 subjects with recent x-ray mammograms available, and average breast tissue composition (water, lipid, collagen, oxy- and deoxyhemoglobin) and scattering parameters (amplitude a and slope b) were estimated. Correlation was observed between optically derived parameters and mammographic density [Breast Imaging and Reporting Data System (BI-RADS) categories], which is a strong risk factor for breast cancer. A regression logistic model was obtained to best identify high-risk (BI-RADS 4) subjects, based on collagen content and scattering parameters. The model presents a total misclassification error of 12.3%, sensitivity of 69%, specificity of 94%, and simple kappa of 0.84, which compares favorably even with intraradiologist assignments of BI-RADS categories.

  2. 13 CFR 140.11 - What type of debt is subject to administrative wage garnishment, and how can SBA administratively...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... contain the signature of, or the image of the signature of, SBA's Administrator or his/her delegatee. The... notifies your employer to stop wage garnishment. (j ) Exclusions from garnishment. The Agency may not...

  3. 13 CFR 140.11 - What type of debt is subject to administrative wage garnishment, and how can SBA administratively...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... contain the signature of, or the image of the signature of, SBA's Administrator or his/her delegatee. The... notifies your employer to stop wage garnishment. (j ) Exclusions from garnishment. The Agency may not...

  4. 13 CFR 140.11 - What type of debt is subject to administrative wage garnishment, and how can SBA administratively...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... contain the signature of, or the image of the signature of, SBA's Administrator or his/her delegatee. The... notifies your employer to stop wage garnishment. (j ) Exclusions from garnishment. The Agency may not...

  5. An Analysis of Category Management of Service Contracts

    DTIC Science & Technology

    2017-12-01

    management teams a way to make informed , data-driven decisions. Data-driven decisions derived from clustering not only align with Category...savings. Furthermore, this methodology provides a data-driven visualization to inform sound business decisions on potential Category Management ...Category Management initiatives. The Maptitude software will allow future research to collect data and develop visualizations to inform Category

  6. Aversive Learning Modulates Cortical Representations of Object Categories

    PubMed Central

    Dunsmoor, Joseph E.; Kragel, Philip A.; Martin, Alex; LaBar, Kevin S.

    2014-01-01

    Experimental studies of conditioned learning reveal activity changes in the amygdala and unimodal sensory cortex underlying fear acquisition to simple stimuli. However, real-world fears typically involve complex stimuli represented at the category level. A consequence of category-level representations of threat is that aversive experiences with particular category members may lead one to infer that related exemplars likewise pose a threat, despite variations in physical form. Here, we examined the effect of category-level representations of threat on human brain activation using 2 superordinate categories (animals and tools) as conditioned stimuli. Hemodynamic activity in the amygdala and category-selective cortex was modulated by the reinforcement contingency, leading to widespread fear of different exemplars from the reinforced category. Multivariate representational similarity analyses revealed that activity patterns in the amygdala and object-selective cortex were more similar among exemplars from the threat versus safe category. Learning to fear animate objects was additionally characterized by enhanced functional coupling between the amygdala and fusiform gyrus. Finally, hippocampal activity co-varied with object typicality and amygdala activation early during training. These findings provide novel evidence that aversive learning can modulate category-level representations of object concepts, thereby enabling individuals to express fear to a range of related stimuli. PMID:23709642

  7. On Monoids in the Category of Sets and Relations

    NASA Astrophysics Data System (ADS)

    Jenčová, Anna; Jenča, Gejza

    2017-12-01

    The category R e l is the category of sets (objects) and relations (morphisms). Equipped with the direct product of sets, R e l is a monoidal category. Moreover, R e l is a locally posetal 2-category, since every homset R e l( A, B) is a poset with respect to inclusion. We examine the 2-category of monoids R e l M o n in this category. The morphism we use are lax. This category includes, as subcategories, various interesting classes: hypergroups, partial monoids (which include various types of quantum logics, for example effect algebras) and small categories. We show how the 2-categorical structure gives rise to several previously defined notions in these categories, for example certain types of congruence relations on generalized effect algebras. This explains where these definitions come from.

  8. Categories for Names or Names of Categories? The Interplay Between Domain-Specific Conceptual Structure and Language.

    ERIC Educational Resources Information Center

    Diesendruck, Gil

    2003-01-01

    Drawing on the notion of the domain-specificity of recognition, reviews evidence on the effect of language in classification of and reasoning about categories from different domains. Looks at anthropological infant classification, and preschool categorization literature. Suggests the causal nature and indicative power of animal categories seem to…

  9. Self-Administration of Cocaine Induces Dopamine-Independent Self-Administration of Sigma Agonists

    PubMed Central

    Hiranita, Takato; Mereu, Maddalena; Soto, Paul L; Tanda, Gianluigi; Katz, Jonathan L

    2013-01-01

    Sigma1 receptors (σ1Rs) are intracellularly mobile chaperone proteins implicated in several disease processes, as well as psychiatric disorders and substance abuse. Here we report that although selective σ1R agonists (PRE-084, (+)-pentazocine) lacked reinforcing effects in drug-naive rats, over the course of 28 experimental sessions, which was more than sufficient for acquisition of cocaine self-administration, responding was not maintained by either σ1R agonist. In contrast, after subjects self-administered cocaine σ1R agonists were readily self-administered. The induced reinforcing effects were long lasting; a response for which subjects had no history of reinforcement was newly conditioned with both σ1R agonists, extinguished when injections were discontinued, and reconditioned when σ1R agonists again followed responses. Experience with food reinforcement was ineffective as an inducer of σ1R agonist reinforcement. Although a variety of dopamine receptor antagonists blocked cocaine self-administration, consistent with its dopaminergic mechanism, PRE-084 self-administration was entirely insensitive to these drugs. Conversely, the σR antagonist, BD1063, blocked PRE-084 self-administration but was inactive against cocaine. In microdialysis studies i.v. PRE-084 did not significantly stimulate dopamine at doses that were self-administered in rats either with or without a cocaine self-administration experience. The results indicate that cocaine experience induces reinforcing effects of previously inactive σ1R agonists, and that the mechanism underlying these reinforcing effects is dopamine independent. It is further suggested that induced σ1R mechanisms may have an essential role in treatment-resistant stimulant abuse, suggesting new approaches for the development of effective medications for stimulant abuse. PMID:23187725

  10. Self-administration of cocaine induces dopamine-independent self-administration of sigma agonists.

    PubMed

    Hiranita, Takato; Mereu, Maddalena; Soto, Paul L; Tanda, Gianluigi; Katz, Jonathan L

    2013-03-01

    Sigma(1) receptors (σ(1)Rs) are intracellularly mobile chaperone proteins implicated in several disease processes, as well as psychiatric disorders and substance abuse. Here we report that although selective σ(1)R agonists (PRE-084, (+)-pentazocine) lacked reinforcing effects in drug-naive rats, over the course of 28 experimental sessions, which was more than sufficient for acquisition of cocaine self-administration, responding was not maintained by either σ(1)R agonist. In contrast, after subjects self-administered cocaine σ(1)R agonists were readily self-administered. The induced reinforcing effects were long lasting; a response for which subjects had no history of reinforcement was newly conditioned with both σ(1)R agonists, extinguished when injections were discontinued, and reconditioned when σ(1)R agonists again followed responses. Experience with food reinforcement was ineffective as an inducer of σ(1)R agonist reinforcement. Although a variety of dopamine receptor antagonists blocked cocaine self-administration, consistent with its dopaminergic mechanism, PRE-084 self-administration was entirely insensitive to these drugs. Conversely, the σR antagonist, BD1063, blocked PRE-084 self-administration but was inactive against cocaine. In microdialysis studies i.v. PRE-084 did not significantly stimulate dopamine at doses that were self-administered in rats either with or without a cocaine self-administration experience. The results indicate that cocaine experience induces reinforcing effects of previously inactive σ(1)R agonists, and that the mechanism underlying these reinforcing effects is dopamine independent. It is further suggested that induced σ(1)R mechanisms may have an essential role in treatment-resistant stimulant abuse, suggesting new approaches for the development of effective medications for stimulant abuse.

  11. Diagnostic Categories in Autobiographical Accounts of Illness.

    PubMed

    Kelly, Michael P

    2015-01-01

    Working within frameworks drawn from the writings of Immanuel Kant, Alfred Schutz, and Kenneth Burke, this article examines the role that diagnostic categories play in autobiographical accounts of illness, with a special focus on chronic disease. Four lay diagnostic categories, each with different connections to formal medical diagnostic categories, serve as typifications to make sense of the way the lifeworld changes over the course of chronic illness. These diagnostic categories are used in conjunction with another set of typifications: lay epidemiologies, lay etiologies, lay prognostics, and lay therapeutics. Together these serve to construct and reconstruct the self at the center of the lifeworld. Embedded within the lay diagnostic categories are narratives of progression, regression, or stability, forms of typification derived from literary and storytelling genres. These narratives are developed by the self in autobiographical accounts of illness.

  12. Ad hoc categories and false memories: Memory illusions for categories created on-the-spot.

    PubMed

    Soro, Jerônimo C; Ferreira, Mário B; Semin, Gün R; Mata, André; Carneiro, Paula

    2017-11-01

    Three experiments were designed to test whether experimentally created ad hoc associative networks evoke false memories. We used the DRM (Deese, Roediger, McDermott) paradigm with lists of ad hoc categories composed of exemplars aggregated toward specific goals (e.g., going for a picnic) that do not share any consistent set of features. Experiment 1 revealed considerable levels of false recognitions of critical words from ad hoc categories. False recognitions occurred even when the lists were presented without an organizing theme (i.e., the category's label). Experiments 1 and 2 tested whether (a) the ease of identifying the categories' themes, and (b) the lists' backward associative strength could be driving the effect. List identifiability did not correlate with false recognition, and the effect remained even when backward associative strength was controlled for. Experiment 3 manipulated the distractor items in the recognition task to address the hypothesis that the salience of unrelated items could be facilitating the occurrence of the phenomenon. The effect remained when controlling for this source of facilitation. These results have implications for assumptions made by theories of false memories, namely the preexistence of associations in the activation-monitoring framework and the central role of gist extraction in fuzzy-trace theory, while providing evidence of the occurrence of false memories for more dynamic and context-dependent knowledge structures. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. 45 CFR 63.31 - Protection of human subjects.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Protection of human subjects. 63.31 Section 63.31 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED... Protection of human subjects. All grants made pursuant to this part are subject to the specific provisions of...

  14. 45 CFR 63.31 - Protection of human subjects.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Protection of human subjects. 63.31 Section 63.31 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED... Protection of human subjects. All grants made pursuant to this part are subject to the specific provisions of...

  15. 45 CFR 63.31 - Protection of human subjects.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Protection of human subjects. 63.31 Section 63.31 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED... Protection of human subjects. All grants made pursuant to this part are subject to the specific provisions of...

  16. 45 CFR 63.31 - Protection of human subjects.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Protection of human subjects. 63.31 Section 63.31 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED... Protection of human subjects. All grants made pursuant to this part are subject to the specific provisions of...

  17. 45 CFR 63.31 - Protection of human subjects.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Protection of human subjects. 63.31 Section 63.31 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED... Protection of human subjects. All grants made pursuant to this part are subject to the specific provisions of...

  18. On the classification of weakly integral modular categories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bruillard, Paul; Galindo, César; Ng, Siu-Hung

    In this paper we classify all modular categories of dimension 4m, where m is an odd square-free integer, and all rank 6 and rank 7 weakly integral modular categories. This completes the classification of weakly integral modular categories through rank 7. In particular, our results imply that all integral modular categories of rank at most 7 are pointed (that is, every simple object has dimension 1). All the non-integral (but weakly integral) modular categories of ranks 6 and 7 have dimension 4m, with m an odd square free integer, so their classification is an application of our main result. Themore » classification of rank 7 integral modular categories is facilitated by an analysis of the two group actions on modular categories: the Galois group of the field generated by the entries of the S-matrix and the group of invertible isomorphism classes of objects. We derive some valuable arithmetic consequences from these actions.« less

  19. Contextual memory and skill transfer in category search.

    PubMed

    Kole, James A; Healy, Alice F; Fierman, Deanna M; Bourne, Lyle E

    2010-01-01

    In three experiments, we examined transfer and contextual memory in a category search task. Each experiment included two phases (training and test), during which participants searched through category and exemplar menus for targets. In Experiment 1, the targets were from one of two domains during training (grocery store or department store); the domain was either the same or changed at test. Also, the categories were organized in one of two ways (alphabetically or semantically); the organization either remained the same or changed at test. In Experiments 2 and 3, domain and organization were held constant; however, categories or exemplars were the same, partially replaced, or entirely replaced across phases in order to simulate the dynamic nature of category search in everyday situations. Transfer occurred at test when the category organization or domain was maintained and when the categories or exemplars matched (partially or entirely) those at training. These results demonstrate that transfer is facilitated by overlap in training and testing contexts.

  20. How Category Structure Influences the Perception of Object Similarity: The Atypicality Bias

    PubMed Central

    Tanaka, James William; Kantner, Justin; Bartlett, Marni

    2011-01-01

    Why do some faces appear more similar than others? Beyond structural factors, we speculate that similarity is governed by the organization of faces located in a multi-dimensional face space. To test this hypothesis, we morphed a typical face with an atypical face. If similarity judgments are guided purely by their physical properties, the morph should be perceived to be equally similar to its typical parent as its atypical parent. However, contrary to the structural prediction, our results showed that the morph face was perceived to be more similar to the atypical face than the typical face. Our empirical studies show that the atypicality bias is not limited to faces, but extends to other object categories (birds) whose members share common shape properties. We also demonstrate atypicality bias is malleable and can change subject to category learning and experience. Collectively, the empirical evidence indicates that perceptions of face and object similarity are affected by the distribution of stimuli in a face or object space. In this framework, atypical stimuli are located in a sparser region of the space where there is less competition for recognition and therefore, these representations capture a broader range of inputs. In contrast, typical stimuli are located in a denser region of category space where there is increased competition for recognition and hence, these representation draw a more restricted range of face inputs. These results suggest that the perceived likeness of an object is influenced by the organization of surrounding exemplars in the category space. PMID:22685441

  1. Nurses' reported thinking during medication administration.

    PubMed

    Eisenhauer, Laurel A; Hurley, Ann C; Dolan, Nancy

    2007-01-01

    To document nurses' reported thinking processes during medication administration before and after implementation of point-of-care technology. Semistructured interviews and real-time tape recordings were used to document the thinking processes of 40 nurses practicing in inpatient care units in a large tertiary care teaching hospital in the northeastern US. Content analysis resulted in identification of 10 descriptive categories of nurses' thinking: communication, dose-time, checking, assessment, evaluation, teaching, side effects, work arounds, anticipating problem solving, and drug administration. Situations requiring judgment in dosage, timing, or selection of specific medications (e.g., pain management, titration of antihypertensives) provided the most explicit data about nurses' use of critical thinking and clinical judgment. A key element was nurses' constant professional vigilance to ensure that patients received their appropriate medications. Nurses' thinking processes extended beyond rules and procedures and were based on patient data and interdisciplinary professional knowledge to provide safe and effective care. Identification of thinking processes can help nurses to explain the professional expertise inherent in medication administration beyond the technical application of the "5 rights."

  2. Classification versus inference learning contrasted with real-world categories.

    PubMed

    Jones, Erin L; Ross, Brian H

    2011-07-01

    Categories are learned and used in a variety of ways, but the research focus has been on classification learning. Recent work contrasting classification with inference learning of categories found important later differences in category performance. However, theoretical accounts differ on whether this is due to an inherent difference between the tasks or to the implementation decisions. The inherent-difference explanation argues that inference learners focus on the internal structure of the categories--what each category is like--while classification learners focus on diagnostic information to predict category membership. In two experiments, using real-world categories and controlling for earlier methodological differences, inference learners learned more about what each category was like than did classification learners, as evidenced by higher performance on a novel classification test. These results suggest that there is an inherent difference between learning new categories by classifying an item versus inferring a feature.

  3. Category mistakes: A barrier to effective environmental management.

    PubMed

    Wallace, Ken J; Jago, Mark

    2017-09-01

    How entities, the things that exist, are defined and categorised affects all aspects of environmental management including technical descriptions, quantitative analyses, participatory processes, planning, and decisions. Consequently, ambiguous definitions and wrongly assigning entities to categories, referred to as category mistakes, are barriers to effective management. Confusion caused by treating the term 'biodiversity' variously as the property of an area, the biota of an area, and a preferred end state (a value) - quite different categories of entities - is one example. To overcome such difficulties, we develop and define four entity categories - elements, processes, properties, and values - and two derived categories - states and systems. We argue that adoption of these categories and definitions will significantly improve environmental communication and analysis, and thus strengthen planning and decision-making. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Administration of antioxidant vitamins does not alter plasma fibrinolytic activity in subjects with central obesity.

    PubMed

    Rifici, V A; Schneider, S H; Chen, Y; Khachadurian, A K

    1997-09-01

    In vitro studies suggest that oxidized low density lipoprotein inhibits fibrinolysis by stimulating the production of plasminogen activator inhibitor -1 (PAI). We assessed the effects of dietary antioxidant vitamins for four weeks on three indices of copper mediated oxidation of very low and low density lipoproteins (VLDL+LDL) and plasma fibrinolytic activities in 15 male subjects with central obesity, a condition associated with increased PAI activity. Vitamin administration resulted in a decrease in production of thiobarbituric acid reactive substances from 29.3 +/- 3.9 to 13.6 +/- 3.5 nmoles/mg VLDL + LDL protein (mean +/- SE, p <0.003), an increase in the lag phase of conjugated diene formation from 94.8 +/- 5.5 to 225.0 +/- 31.9 min (p <0.001) and an increase in reactivity of lysine residues from 73.6% +/- 4.8% to 86.8% +/- 3.6% (p <0.034) demonstrating a reduction in the susceptibility of the lipoproteins to oxidation. However, antioxidant vitamins had no effect on plasma PAI activity, PAI antigen, tissue-type plasminogen activator activity and antigen, fibrinogen and fibrin degradation products. These results do not support the hypothesis that lipoprotein oxidation is a significant cause of impaired fibrinolysis in men with central obesity.

  5. Adult and child use of love, like, don't like and hate during family mealtimes. Subjective category assessments as food preference talk.

    PubMed

    Wiggins, Sally

    2014-09-01

    Food preference is now a ubiquitous concept in eating research, and closely associated with actual consumption, particularly in relation to children's food preferences. Research in this area is beginning to reveal the effects of parent-child interaction on eating practices though relatively little attention has been paid to the discursive and lexical processes involved. Food preferences are typically associated with the terms 'likes' and 'dislikes' in food preference research. By contrast, adults and children typically use the terms 'love', 'like', 'don't like' and 'hate' to construct and manage food preferences in everyday meal conversations. A corpus of 270 video- and audio-recorded English and Scottish family mealtimes, involving children aged 1-17 years, was searched and analysed for any and all occurrences of subjective category assessments (SCAs; e.g., 'I like X'), featuring the terms 'love', 'like', 'don't like' and 'hate'. Discursive psychology was used to analyse the transcripts and recordings, and illustrated the disparity between adult and child use of SCAs and food preference talk. Within the data set, parents typically made claims about what their children like, and in doing so claimed epistemic primacy over their children's food preferences. Children, by contrast, typically made claims about their own 'don't likes' and likes, and these were frequently countered by their parents or treated as inappropriate claims. Implications for how parents and researchers might reorient to the food preferences lexicon are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Behavior-based aggregation of land categories for temporal change analysis

    NASA Astrophysics Data System (ADS)

    Aldwaik, Safaa Zakaria; Onsted, Jeffrey A.; Pontius, Robert Gilmore, Jr.

    2015-03-01

    Comparison between two time points of the same categorical variable for the same study extent can reveal changes among categories over time, such as transitions among land categories. If many categories exist, then analysis can be difficult to interpret. Category aggregation is the procedure that combines two or more categories to create a single broader category. Aggregation can simplify interpretation, and can also influence the sizes and types of changes. Some classifications have an a priori hierarchy to facilitate aggregation, but an a priori aggregation might make researchers blind to important category dynamics. We created an algorithm to aggregate categories in a sequence of steps based on the categories' behaviors in terms of gross losses and gross gains. The behavior-based algorithm aggregates net gaining categories with net gaining categories and aggregates net losing categories with net losing categories, but never aggregates a net gaining category with a net losing category. The behavior-based algorithm at each step in the sequence maintains net change and maximizes swap change. We present a case study where data from 2001 and 2006 for 64 land categories indicate change on 17% of the study extent. The behavior-based algorithm produces a set of 10 categories that maintains nearly the original amount of change. In contrast, an a priori aggregation produces 10 categories while reducing the change to 9%. We offer a free computer program to perform the behavior-based aggregation.

  7. Psychopathic disorder: a category mistake?

    PubMed Central

    Holmes, C A

    1991-01-01

    Although the concept of psychopathy retains its currency in British psychiatry, apparently being meaningful as well as useful to practitioners (1), it is often taken to refer to a purely legal category with social control functions rather than a medical diagnosis with treatment implications. I wish, in this brief article, to suggest that it is essentially, and most usefully, an ethical category which stands outside the diagnostic framework of present-day psychiatry. PMID:1870086

  8. Professional Development Challenges for Educational Administrators: A Culminating Summary of Conference Themes.

    ERIC Educational Resources Information Center

    Schmuck, Richard A.

    Among the primary social pressures on schools to change are the demands for individualization, relevance, accountability, educational technology, and humanizing relationships. These five pressures challenge the educational administrator and offer categories in which to plan professional development activities. The adaptive school is an avenue for…

  9. Neuronal coding of implicit emotion categories in the subcallosal cortex in patients with depression.

    PubMed

    Laxton, Adrian W; Neimat, Joseph S; Davis, Karen D; Womelsdorf, Thilo; Hutchison, William D; Dostrovsky, Jonathan O; Hamani, Clement; Mayberg, Helen S; Lozano, Andres M

    2013-11-15

    The subcallosal cingulate and adjacent ventromedial prefrontal cortex (collectively referred to here as the subcallosal cortex or SCC) have been identified as key brain areas in emotional processing. The SCC's role in affective valuation as well as severe mood and motivational disturbances, such as major depression, has been largely inferred from measures of neuronal population activity using functional neuroimaging. On the basis of imaging studies, it is unclear whether the SCC predominantly processes 1) negatively valenced affective content, 2) affective arousal, or 3) category-specific affective information. To clarify these putative functional roles of the SCC, we measured single neuron activity in the SCC of 15 human subjects undergoing deep brain stimulation for depression while they viewed emotionally evocative images grouped into categories that varied in emotional valence (pleasantness) and arousal. We found that the majority of responsive neurons were modulated by specific emotion categories, rather than by valence or arousal alone. Moreover, although these emotion-category-specific neurons responded to both positive and negative emotion categories, a significant majority were selective for negatively valenced emotional content. These findings reveal that single SCC neuron activity reflects the automatic valuational processing and implicit emotion categorization of visual stimuli. Furthermore, because of the predominance of neuronal signals in SCC conveying negative affective valuations and the increased activity in this region among depressed people, the effectiveness of depression therapies that alter SCC neuronal activity may relate to the down-regulation of a previously negative emotional processing bias. © 2013 Society of Biological Psychiatry.

  10. Category-contingent face adaptation for novel colour categories: Contingent effects are seen only after social or meaningful labelling.

    PubMed

    Little, Anthony C; DeBruine, Lisa M; Jones, Benedict C

    2011-01-01

    A face appears normal when it approximates the average of a population. Consequently, exposure to faces biases perceptions of subsequently viewed faces such that faces similar to those recently seen are perceived as more normal. Simultaneously inducing such aftereffects in opposite directions for two groups of faces indicates somewhat discrete representations for those groups. Here we examine how labelling influences the perception of category in faces differing in colour. We show category-contingent aftereffects following exposure to faces differing in eye spacing (wide versus narrow) for blue versus red faces when such groups are consistently labelled with socially meaningful labels (Extravert versus Introvert; Soldier versus Builder). Category-contingent aftereffects were not seen using identical methodology when labels were not meaningful or were absent. These data suggest that human representations of faces can be rapidly tuned to code for meaningful social categories and that such tuning requires both a label and an associated visual difference. Results highlight the flexibility of the cognitive visual system to discriminate categories even in adulthood. Copyright © 2010 Elsevier B.V. All rights reserved.

  11. How do People Solve the “Weather Prediction” Task?: Individual Variability in Strategies for Probabilistic Category Learning

    PubMed Central

    Gluck, Mark A.; Shohamy, Daphna; Myers, Catherine

    2002-01-01

    Probabilistic category learning is often assumed to be an incrementally learned cognitive skill, dependent on nondeclarative memory systems. One paradigm in particular, the weather prediction task, has been used in over half a dozen neuropsychological and neuroimaging studies to date. Because of the growing interest in using this task and others like it as behavioral tools for studying the cognitive neuroscience of cognitive skill learning, it becomes especially important to understand how subjects solve this kind of task and whether all subjects learn it in the same way. We present here new experimental and theoretical analyses of the weather prediction task that indicate that there are at least three different strategies that describe how subjects learn this task. (1) An optimal multi-cue strategy, in which they respond to each pattern on the basis of associations of all four cues with each outcome; (2) a one-cue strategy, in which they respond on the basis of presence or absence of a single cue, disregarding all other cues; or (3) a singleton strategy, in which they learn only about the four patterns that have only one cue present and all others absent. This variability in how subjects approach this task may have important implications for interpreting how different brain regions are involved in probabilistic category learning. PMID:12464701

  12. Observation versus classification in supervised category learning.

    PubMed

    Levering, Kimery R; Kurtz, Kenneth J

    2015-02-01

    The traditional supervised classification paradigm encourages learners to acquire only the knowledge needed to predict category membership (a discriminative approach). An alternative that aligns with important aspects of real-world concept formation is learning with a broader focus to acquire knowledge of the internal structure of each category (a generative approach). Our work addresses the impact of a particular component of the traditional classification task: the guess-and-correct cycle. We compare classification learning to a supervised observational learning task in which learners are shown labeled examples but make no classification response. The goals of this work sit at two levels: (1) testing for differences in the nature of the category representations that arise from two basic learning modes; and (2) evaluating the generative/discriminative continuum as a theoretical tool for understand learning modes and their outcomes. Specifically, we view the guess-and-correct cycle as consistent with a more discriminative approach and therefore expected it to lead to narrower category knowledge. Across two experiments, the observational mode led to greater sensitivity to distributional properties of features and correlations between features. We conclude that a relatively subtle procedural difference in supervised category learning substantially impacts what learners come to know about the categories. The results demonstrate the value of the generative/discriminative continuum as a tool for advancing the psychology of category learning and also provide a valuable constraint for formal models and associated theories.

  13. Test-retest reliability of the underlying latent factor structure of alcohol subjective response.

    PubMed

    Lutz, Joseph A; Childs, Emma

    2017-04-01

    Alcohol subjective experiences are multi-dimensional and demonstrate wide inter-individual variability. Recent efforts have sought to establish a clearer understanding of subjective alcohol responses by identifying core constructs derived from multiple measurement instruments. The aim of this study was to evaluate the temporal stability of this approach to conceptualizing alcohol subjective experiences across successive alcohol administrations in the same individuals. Healthy moderate alcohol drinkers (n = 104) completed six experimental sessions each, three with alcohol (0.8 g/kg), and three with a non-alcoholic control beverage. Participants reported subjective mood and drug effects using standardized questionnaires before and at repeated times after beverage consumption. We explored the underlying latent structure of subjective responses for all alcohol administrations using exploratory factor analysis and then tested measurement invariance over the three successive administrations using multi-group confirmatory factor analyses. Exploratory factor analyses on responses to alcohol across all administrations yielded four factors representing "Positive mood," "Sedation," "Stimulation/Euphoria," and "Drug effects and Urges." A confirmatory factor analysis on the separate administrations indicated acceptable configural and metric invariance and moderate scalar invariance. In this study, we demonstrate temporal stability of the underlying constructs of subjective alcohol responses derived from factor analysis. These findings strengthen the utility of this approach to conceptualizing subjective alcohol responses especially for use in prospective and longitudinal alcohol challenge studies relating subjective response to alcohol use disorder risk.

  14. Social categories as markers of intrinsic interpersonal obligations.

    PubMed

    Rhodes, Marjorie; Chalik, Lisa

    2013-06-01

    Social categorization is an early-developing feature of human social cognition, yet the role that social categories play in children's understanding of and predictions about human behavior has been unclear. In the studies reported here, we tested whether a foundational functional role of social categories is to mark people as intrinsically obligated to one another (e.g., obligated to protect rather than harm). In three studies, children (aged 3-9, N = 124) viewed only within-category harm as violating intrinsic obligations; in contrast, they viewed between-category harm as violating extrinsic obligations defined by explicit rules. These data indicate that children view social categories as marking patterns of intrinsic interpersonal obligations, suggesting that a key function of social categories is to support inferences about how people will relate to members of their own and other groups.

  15. Conceptual Influences on Category-Based Induction

    ERIC Educational Resources Information Center

    Gelman, Susan A.; Davidson, Natalie S.

    2013-01-01

    One important function of categories is to permit rich inductive inferences. Prior work shows that children use category labels to guide their inductive inferences. However, there are competing theories to explain this phenomenon, differing in the roles attributed to conceptual information vs. perceptual similarity. Seven experiments with 4- to…

  16. The neural basis for category-specific knowledge: an fMRI study.

    PubMed

    Grossman, Murray; Koenig, Phyllis; DeVita, Chris; Glosser, Guila; Alsop, David; Detre, John; Gee, James

    2002-04-01

    Functional neuroimaging studies of healthy adults have associated different categories of knowledge with distinct activation patterns. The basis for these recruitment patterns has been controversial, due in part to the limited range of categories that has been studied. We used fMRI to monitor regional cortical recruitment patterns while subjects were exposed to printed names of Animals, Implements, and Abstract nouns. Both Implements and Abstract nouns were related to recruitment of left posterolateral temporal cortex and left prefrontal cortex, and Abstract nouns additionally recruited posterolateral temporal and prefrontal regions of the right hemisphere. Animals were associated with activation of ventral-medial occipital cortex in the left hemisphere at a level that approaches significance. These findings are not consistent with the "sensory-motor" model proposed to explain the neural representation of word knowledge. We suggest instead a neural model of semantic memory that reflects the processes common to understanding Implements and Abstract nouns and a selective sensitivity, possibly evolving from adaptive pressures, to the overlapping, intercorrelated visual characteristics of Animals. (C)2002 Elsevier Science (USA).

  17. 33 CFR 151.35 - Certificates needed to carry Category D NLS and Category D Oil-like NLS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protocol on Environmental Protection to the Antarctic Treaty as it Pertains to Pollution from Ships Noxious Liquid Substance Pollution § 151.35 Certificates needed to carry Category D NLS and Category D Oil-like... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID...

  18. Pharmacokinetics of betamethasone after single-dose intramuscular administration of betamethasone phosphate and betamethasone acetate to healthy subjects.

    PubMed

    Salem, Isam I; Najib, Naji M

    2012-01-01

    Betamethasone is used for its antiinflammatory and immunosuppressive effects in disorders of many organ systems. However, the pharmacokinetic properties of betamethasone in plasma after intramuscular injection of betamethasone sodium phosphate and betamethasone acetate dual-acting suspension need further investigation. The main aim of this study was to determine the pharmacokinetic parameters of betamethasone, betamethasone acetate, and betamethasone phosphate after the administration of a single intramuscular dose of the dual-acting suspension to healthy human volunteers. Two different studies were conducted in healthy males. Volunteers were judged healthy based on their medical history, physical examination, and laboratory test results. Before confinement, all volunteers were tested for freedom from alcohol and drugs of abuse. Following a 10-hour overnight fasting, a single dose of 1 mL of the dual-acting suspension containing 3 mg of betamethasone phosphate and 3 mg of betamethasone acetate was administered by intramuscular injection. Blood sampling covered 48 hours. The plasma samples obtained in the second study were stabilized to enable pharmacokinetic profiling of betamethasone esters. Twenty-four healthy males with mean (SD) age of 27 (6.62) years participated in each study. No incidences of serious adverse events were recorded during the studies. Six mild adverse events were reported in 2 subjects in the second study. One subject suffered from pain at the injection site and insomnia, and another subject complained of heartburn and drowsiness. Betamethasone phosphate appeared to be readily absorbed with a mean AUC(0-t) of 96.01 ng/h/mL and an AUC(0-∞) of 97.96 (23.38) ng/h/mL. Betamethasone peak plasma concentration reached a mean t(½) of 12.92 hours. Betamethasone acetate was not detected in the volunteers' plasma in either study (total of 2208 plasma samples). The observed pharmacokinetic parameters suggested that the acetate ester, and not the

  19. Learning, retention, and generalization of haptic categories

    NASA Astrophysics Data System (ADS)

    Do, Phuong T.

    This dissertation explored how haptic concepts are learned, retained, and generalized to the same or different modality. Participants learned to classify objects into three categories either visually or haptically via different training procedures, followed by an immediate or delayed transfer test. Experiment I involved visual versus haptic learning and transfer. Intermodal matching between vision and haptics was investigated in Experiment II. Experiments III and IV examined intersensory conflict in within- and between-category bimodal situations to determine the degree of perceptual dominance between sight and touch. Experiment V explored the intramodal relationship between similarity and categorization in a psychological space, as revealed by MDS analysis of similarity judgments. Major findings were: (1) visual examination resulted in relatively higher performance accuracy than haptic learning; (2) systematic training produced better category learning of haptic concepts across all modality conditions; (3) the category prototypes were rated newer than any transfer stimulus followed learning both immediately and after a week delay; and, (4) although they converged at the apex of two transformational trajectories, the category prototypes became more central to their respective categories and increasingly structured as a function of learning. Implications for theories of multimodal similarity and categorization behavior are discussed in terms of discrimination learning, sensory integration, and dominance relation.

  20. 46 CFR 120.352 - Battery categories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Battery categories. 120.352 Section 120.352 Shipping... and Distribution Systems § 120.352 Battery categories. This section applies to batteries installed to... sources of power to final emergency loads. (a) Large. A large battery installation is one connected to a...

  1. 46 CFR 183.352 - Battery categories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Battery categories. 183.352 Section 183.352 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements of § 183.310 for secondary sources of power to...

  2. 7 CFR 993.503 - Size category.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Size category. 993.503 Section 993.503 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... categories listed in § 993.515 and fixes the range or the limits of the various size counts. Effective Date...

  3. 46 CFR 120.352 - Battery categories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Battery categories. 120.352 Section 120.352 Shipping... and Distribution Systems § 120.352 Battery categories. This section applies to batteries installed to... sources of power to final emergency loads. (a) Large. A large battery installation is one connected to a...

  4. 46 CFR 183.352 - Battery categories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Battery categories. 183.352 Section 183.352 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements of § 183.310 for secondary sources of power to...

  5. 46 CFR 120.352 - Battery categories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Battery categories. 120.352 Section 120.352 Shipping... and Distribution Systems § 120.352 Battery categories. This section applies to batteries installed to... sources of power to final emergency loads. (a) Large. A large battery installation is one connected to a...

  6. 46 CFR 120.352 - Battery categories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Battery categories. 120.352 Section 120.352 Shipping... and Distribution Systems § 120.352 Battery categories. This section applies to batteries installed to... sources of power to final emergency loads. (a) Large. A large battery installation is one connected to a...

  7. 46 CFR 183.352 - Battery categories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Battery categories. 183.352 Section 183.352 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements of § 183.310 for secondary sources of power to...

  8. 46 CFR 120.352 - Battery categories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Battery categories. 120.352 Section 120.352 Shipping... and Distribution Systems § 120.352 Battery categories. This section applies to batteries installed to... sources of power to final emergency loads. (a) Large. A large battery installation is one connected to a...

  9. 46 CFR 183.352 - Battery categories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Battery categories. 183.352 Section 183.352 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements of § 183.310 for secondary sources of power to...

  10. 46 CFR 183.352 - Battery categories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Battery categories. 183.352 Section 183.352 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements of § 183.310 for secondary sources of power to...

  11. Calculation of Hazard Category 2/3 Threshold Quantities Using Contemporary Dosimetric Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walker, William C.

    The purpose of this report is to describe the methodology and selection of input data utilized to calculate updated Hazard Category 2 and Hazard Category 3 Threshold Quantities (TQs) using contemporary dosimetric information. The calculation of the updated TQs will be considered for use in the revision to the Department of Energy (DOE) Technical Standard (STD-) 1027-92 Change Notice (CN)-1, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports.” The updated TQs documented in this report complement an effort previously undertaken by the National Nuclear Security Administration (NNSA), which in 2014 issued revisedmore » Supplemental Guidance documenting the calculation of updated TQs for approximately 100 radionuclides listed in DOE-STD-1027-92, CN-1. The calculations documented in this report complement the NNSA effort by expanding the set of radionuclides to more than 1,250 radionuclides with a published TQ. The development of this report was sponsored by the Department of Energy’s Office of Nuclear Safety (AU-30) within the Associate Under Secretary for Environment, Health, Safety, and Security organization.« less

  12. Aripiprazole maintenance increases smoked cocaine self-administration in humans

    PubMed Central

    Rubin, Eric; Foltin, Richard W.

    2011-01-01

    Rationale Partial dopamine receptor agonists have been proposed as candidate pharmacotherapies for cocaine dependence. Objective This 42-day, within-subject, human laboratory study assessed how maintenance on aripiprazole, a partial D2 receptor agonist, influenced smoked cocaine self-administration, cardiovascular measures, subjective effects, and cocaine craving in nontreatment-seeking, cocaine-dependent volunteers. Methods In order to achieve steady-state concentrations, participants (n=8 men) were administered placebo and aripiprazole (15 mg/day) capsules in counter-balanced order for 21 days. A smoked cocaine dose–response curve (0, 12, 25, 50 mg) was determined twice under placebo and aripiprazole maintenance. Sessions comprised a “sample” trial, when participants smoked the cocaine dose available that session, and five choice trials, when they responded on a progressive-ratio schedule of reinforcement to receive the cocaine dose or receive $5.00. Results Cocaine’s reinforcing, subjective, and cardiovascular effects were dose-dependent. Aripiprazole significantly increased cocaine (12, 25 mg) self-administration. Following a single administration of cocaine (25 mg), aripiprazole decreased ratings of how much participants would pay for that dose. Following repeated cocaine (50 mg) self-administration, aripiprazole decreased ratings of cocaine quality, craving, and good drug effect as compared to placebo. Conclusions These data suggest that aripiprazole may have increased self-administration to compensate for a blunted subjective cocaine effect. Overall, the findings do not suggest aripiprazole would be useful for treating cocaine dependence. PMID:21373790

  13. 46 CFR 129.353 - Battery categories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Battery categories. 129.353 Section 129.353 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.353 Battery categories. This section applies to batteries installed to meet the requirements of § 129.310(a) for secondary sources of power to vital loads...

  14. 46 CFR 129.353 - Battery categories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Battery categories. 129.353 Section 129.353 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.353 Battery categories. This section applies to batteries installed to meet the requirements of § 129.310(a) for secondary sources of power to vital loads...

  15. 46 CFR 129.353 - Battery categories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Battery categories. 129.353 Section 129.353 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.353 Battery categories. This section applies to batteries installed to meet the requirements of § 129.310(a) for secondary sources of power to vital loads...

  16. 46 CFR 129.353 - Battery categories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Battery categories. 129.353 Section 129.353 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.353 Battery categories. This section applies to batteries installed to meet the requirements of § 129.310(a) for secondary sources of power to vital loads...

  17. 46 CFR 129.353 - Battery categories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Battery categories. 129.353 Section 129.353 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.353 Battery categories. This section applies to batteries installed to meet the requirements of § 129.310(a) for secondary sources of power to vital loads...

  18. The Role of Grammatical Category Information in Spoken Word Retrieval

    PubMed Central

    Duràn, Carolina Palma; Pillon, Agnesa

    2011-01-01

    We investigated the role of lexical syntactic information such as grammatical gender and category in spoken word retrieval processes by using a blocking paradigm in picture and written word naming experiments. In Experiments 1, 3, and 4, we found that the naming of target words (nouns) from pictures or written words was faster when these target words were named within a list where only words from the same grammatical category had to be produced (homogeneous category list: all nouns) than when they had to be produced within a list comprising also words from another grammatical category (heterogeneous category list: nouns and verbs). On the other hand, we detected no significant facilitation effect when the target words had to be named within a homogeneous gender list (all masculine nouns) compared to a heterogeneous gender list (both masculine and feminine nouns). In Experiment 2, using the same blocking paradigm by manipulating the semantic category of the items, we found that naming latencies were significantly slower in the semantic category homogeneous in comparison with the semantic category heterogeneous condition. Thus semantic category homogeneity caused an interference, not a facilitation effect like grammatical category homogeneity. Finally, in Experiment 5, nouns in the heterogeneous category condition had to be named just after a verb (category-switching position) or a noun (same-category position). We found a facilitation effect of category homogeneity but no significant effect of position, which showed that the effect of category homogeneity found in Experiments 1, 3, and 4 was not due to a cost of switching between grammatical categories in the heterogeneous grammatical category list. These findings supported the hypothesis that grammatical category information impacts word retrieval processes in speech production, even when words are to be produced in isolation. They are discussed within the context of extant theories of lexical production. PMID

  19. The role of grammatical category information in spoken word retrieval.

    PubMed

    Duràn, Carolina Palma; Pillon, Agnesa

    2011-01-01

    We investigated the role of lexical syntactic information such as grammatical gender and category in spoken word retrieval processes by using a blocking paradigm in picture and written word naming experiments. In Experiments 1, 3, and 4, we found that the naming of target words (nouns) from pictures or written words was faster when these target words were named within a list where only words from the same grammatical category had to be produced (homogeneous category list: all nouns) than when they had to be produced within a list comprising also words from another grammatical category (heterogeneous category list: nouns and verbs). On the other hand, we detected no significant facilitation effect when the target words had to be named within a homogeneous gender list (all masculine nouns) compared to a heterogeneous gender list (both masculine and feminine nouns). In Experiment 2, using the same blocking paradigm by manipulating the semantic category of the items, we found that naming latencies were significantly slower in the semantic category homogeneous in comparison with the semantic category heterogeneous condition. Thus semantic category homogeneity caused an interference, not a facilitation effect like grammatical category homogeneity. Finally, in Experiment 5, nouns in the heterogeneous category condition had to be named just after a verb (category-switching position) or a noun (same-category position). We found a facilitation effect of category homogeneity but no significant effect of position, which showed that the effect of category homogeneity found in Experiments 1, 3, and 4 was not due to a cost of switching between grammatical categories in the heterogeneous grammatical category list. These findings supported the hypothesis that grammatical category information impacts word retrieval processes in speech production, even when words are to be produced in isolation. They are discussed within the context of extant theories of lexical production.

  20. Uncovering category specificity of genital sexual arousal in women: The critical role of analytic technique.

    PubMed

    Pulverman, Carey S; Hixon, J Gregory; Meston, Cindy M

    2015-10-01

    Based on analytic techniques that collapse data into a single average value, it has been reported that women lack category specificity and show genital sexual arousal to a large range of sexual stimuli including those that both match and do not match their self-reported sexual interests. These findings may be a methodological artifact of the way in which data are analyzed. This study examined whether using an analytic technique that models data over time would yield different results. Across two studies, heterosexual (N = 19) and lesbian (N = 14) women viewed erotic films featuring heterosexual, lesbian, and gay male couples, respectively, as their physiological sexual arousal was assessed with vaginal photoplethysmography. Data analysis with traditional methods comparing average genital arousal between films failed to detect specificity of genital arousal for either group. When data were analyzed with smoothing regression splines and a within-subjects approach, both heterosexual and lesbian women demonstrated different patterns of genital sexual arousal to the different types of erotic films, suggesting that sophisticated statistical techniques may be necessary to more fully understand women's genital sexual arousal response. Heterosexual women showed category-specific genital sexual arousal. Lesbian women showed higher arousal to the heterosexual film than the other films. However, within subjects, lesbian women showed significantly different arousal responses suggesting that lesbian women's genital arousal discriminates between different categories of stimuli at the individual level. Implications for the future use of vaginal photoplethysmography as a diagnostic tool of sexual preferences in clinical and forensic settings are discussed. © 2015 Society for Psychophysiological Research.

  1. Infinite Index Subfactors and the GICAR Categories

    NASA Astrophysics Data System (ADS)

    Jones, Vaughan F. R.; Penneys, David

    2015-10-01

    Given a II1-subfactor of arbitrary index, we show that the rectangular GICAR category, also called the rectangular planar rook category, faithfully embeds as A - A bimodule maps among the bimodules . As a corollary, we get a lower bound on the dimension of the centralizer algebras for infinite index subfactors, and we also get that is nonabelian for , where is the Jones tower for . We also show that the annular GICAR/planar rook category acts as maps amongst the A-central vectors in , although this action may be degenerate. We prove these results in more generality using bimodules. The embedding of the GICAR category builds on work of Connes and Evans, who originally found GICAR algebras inside Temperley-Lieb algebras with finite modulus.

  2. The Effect of Cumin cyminum L. Plus Lime Administration on Weight Loss and Metabolic Status in Overweight Subjects: A Randomized Double-Blind Placebo-Controlled Clinical Trial.

    PubMed

    Taghizadeh, Mohsen; Memarzadeh, Mohammad Reza; Abedi, Fatemeh; Sharifi, Nasrin; Karamali, Fatemeh; Fakhrieh Kashan, Zohreh; Asemi, Zatollah

    2016-08-01

    Limited data are available regarding the effects of combined administration of Cumin cyminum L. and lime on weight loss and metabolic profiles among subjects with overweight subjects. The current study aimed to assess the effects of combined administration of Cumin cyminum L. and lime on weight loss and metabolic profiles among subjects with overweight. This randomized double-blind placebo-controlled clinical trial was conducted on 72 subjects with overweight, aged 18 - 50 years old. Participants were randomly divided into three groups: Group A received high-dose Cumin cyminum L. and lime capsules (75 mg each, n = 24), group B low-dose Cumin cyminum L. and lime capsules (25 mg each, n = 24) and group C placebos (n = 24) twice daily for eight weeks. After eight weeks of intervention, compared with low-dose C. cyminum L. plus lime and placebo, taking high-dose C. cyminum L. plus lime resulted in significant weight loss (in the high-dose group: -2.1 ± 1.7 vs. in the low-dose group: -1.2 ± 1.5 and in the placebo group: + 0.2 ± 1.3 kg, respectively; P < 0.001) and body mass index (-0.8 ± 0.6 vs. -0.5 ± 0.5 and +0.1 ± 0.5 kg/m 2 , respectively; P < 0.001). In addition, administration of high-dose C. cyminum L. plus lime compared with low-dose C. cyminum L. plus lime and placebo, led to a significant reduction in fasting plasma glucose (FPG) (P < 0.001) and a significant rise in quantitative insulin sensitivity check index (QUICKI) (+ 0.02 ± 0.02 vs. + 0.01 ± 0.02 and 0.01 ± 0.01, respectively; P = 0.01). Moreover, a significant decrease in serum triglycerides (-14.1 ± 56.2 vs. +13.9 ± 36.8 and + 10.6 ± 25.1 mg/dL; respectively; P = 0.03), total-cholesterol (-18.4 ± 28.6 vs. +8.6 ± 28.5 and -1.0 ± 24.8 mg/dL; respectively; P = 0.004) and low density lipoproteins- (LDL)-cholesterol levels (-11.8 ± 20.7 vs. +6.5 ± 23.2 and -2.9 ± 20.4 mg/dL, respectively; P = 0.01) was observed following the consumption of high-dose C. cyminum L. plus lime compared with

  3. Geometric Representation of Association between Categories

    ERIC Educational Resources Information Center

    Heiser, Willem J.

    2004-01-01

    Categories can be counted, rated, or ranked, but they cannot be measured. Likewise, persons or individuals can be counted, rated, or ranked, but they cannot be measured either. Nevertheless, psychology has realized early on that it can take an indirect road to measurement: What can be measured is the strength of association between categories in…

  4. The effect of response scale, administration mode, and format on responses to the CAHPS Clinician and Group survey.

    PubMed

    Drake, Keith M; Hargraves, J Lee; Lloyd, Stephanie; Gallagher, Patricia M; Cleary, Paul D

    2014-08-01

    To examine how different response scales, methods of survey administration, and survey format affect responses to the CAHPS (Consumer Assessment of Healthcare Providers and Systems) Clinician and Group (CG-CAHPS) survey. A total of 6,500 patients from a university health center were randomly assigned to receive the following: standard 12-page mail surveys using 4-category or 6-category response scales (on CG-CAHPS composite items), telephone surveys using 4-category or 6-category response scales, or four-page mail surveys. A total of 3,538 patients completed surveys. Composite score means and provider-level reliabilities did not differ between respondents receiving 4-category or 6-category response scale surveys or between 12-page and four-page mail surveys. Telephone respondents gave more positive responses than mail respondents. We recommend using 4-category response scales and the four-page mail CG-CAHPS survey. © Health Research and Educational Trust.

  5. An investigation of time course of category and semantic priming.

    PubMed

    Ray, Suchismita

    2008-04-01

    Low semantically similar exemplars in a category demonstrate the category-priming effect through priming of the category (i.e., exemplar-category-exemplar), whereas high semantically similar exemplars in the same category demonstrate the semantic-priming effect (i.e., direct activation of one high semantically similar exemplar by another). The author asked whether the category- and semantic-priming effects are based on a common memory process. She examined this question by testing the time courses of category- and semantic-priming effects. She tested participants on either category- or semantic-priming paradigm at 2 different time intervals (6 min and 42 min) by using a lexical decision task using exemplars from categories. Results showed that the time course of category priming was different from that of semantic priming. The author concludes that these 2 priming effects are based on 2 separate memory processes.

  6. The Conceptual Grouping Effect: Categories Matter (and Named Categories Matter More)

    ERIC Educational Resources Information Center

    Lupyan, Gary

    2008-01-01

    Do conceptual categories affect basic visual processing? A conceptual grouping effect for familiar stimuli is reported using a visual search paradigm. Search through conceptually-homogeneous non-targets was faster and more efficient than search through conceptually-heterogeneous non-targets. This effect cannot be attributed to perceptual factors…

  7. Color categories affect pre-attentive color perception.

    PubMed

    Clifford, Alexandra; Holmes, Amanda; Davies, Ian R L; Franklin, Anna

    2010-10-01

    Categorical perception (CP) of color is the faster and/or more accurate discrimination of colors from different categories than equivalently spaced colors from the same category. Here, we investigate whether color CP at early stages of chromatic processing is independent of top-down modulation from attention. A visual oddball task was employed where frequent and infrequent colored stimuli were either same- or different-category, with chromatic differences equated across conditions. Stimuli were presented peripheral to a central distractor task to elicit an event-related potential (ERP) known as the visual mismatch negativity (vMMN). The vMMN is an index of automatic and pre-attentive visual change detection arising from generating loci in visual cortices. The results revealed a greater vMMN for different-category than same-category change detection when stimuli appeared in the lower visual field, and an absence of attention-related ERP components. The findings provide the first clear evidence for an automatic and pre-attentive categorical code for color. Copyright © 2010 Elsevier B.V. All rights reserved.

  8. Hippocampal BOLD response during category learning predicts subsequent performance on transfer generalization.

    PubMed

    Fera, Francesco; Passamonti, Luca; Herzallah, Mohammad M; Myers, Catherine E; Veltri, Pierangelo; Morganti, Giuseppina; Quattrone, Aldo; Gluck, Mark A

    2014-07-01

    To test a prediction of our previous computational model of cortico-hippocampal interaction (Gluck and Myers [1993, 2001]) for characterizing individual differences in category learning, we studied young healthy subjects using an fMRI-adapted category-learning task that has two phases, an initial phase in which associations are learned through trial-and-error feedback followed by a generalization phase in which previously learned rules can be applied to novel associations (Myers et al. [2003]). As expected by our model, we found a negative correlation between learning-related hippocampal responses and accuracy during transfer, demonstrating that hippocampal adaptation during learning is associated with better behavioral scores during transfer generalization. In addition, we found an inverse relationship between Blood Oxygenation Level Dependent (BOLD) activity in the striatum and that in the hippocampal formation and the orbitofrontal cortex during the initial learning phase. Conversely, activity in the dorsolateral prefrontal cortex, orbitofrontal cortex and parietal lobes dominated over that of the hippocampal formation during the generalization phase. These findings provide evidence in support of theories of the neural substrates of category learning which argue that the hippocampal region plays a critical role during learning for appropriately encoding and representing newly learned information so that that this learning can be successfully applied and generalized to subsequent novel task demands. Copyright © 2013 Wiley Periodicals, Inc.

  9. Effect of Within-Category Spacing on Free Recall

    ERIC Educational Resources Information Center

    Borges, Marilyn A.; Mandler, George

    1972-01-01

    Contrary to previous experiments which found recall with blocked spacing always superior to recall with random" spacings, these experiments found that total recall was a function of two independent factors: (a) category representation, and (b) items per category represented (IPC). Both factors are dependent upon within-category spacing.…

  10. 30 CFR 57.22003 - Mine category or subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for Methane in Metal and Nonmetal Mines Mine Categorization § 57.22003 Mine category or... methane and dusts containing volatile matter. Categories and subcategories are defined as follows: (1) Category I applies to mines that operate within a combustible ore body and either liberate methane or have...

  11. 32 CFR 728.113 - Categories of pay patients.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Categories of pay patients. 728.113 Section 728.113 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND... Pay Patients § 728.113 Categories of pay patients. The categories of patients for whom collection...

  12. Speed of spinal vs general anaesthesia for category-1 caesarean section: a simulation and clinical observation-based study.

    PubMed

    Kathirgamanathan, A; Douglas, M J; Tyler, J; Saran, S; Gunka, V; Preston, R; Kliffer, P

    2013-07-01

    Controversy exists as to whether effective spinal anaesthesia can be achieved as quickly as general anaesthesia for a category-1 caesarean section. Sixteen consultants and three fellows in obstetric anaesthesia were timed performing spinal and general anaesthesia for category-1 caesarean section on a simulator. The simulation time commenced upon entry of the anaesthetist into the operating theatre and finished for the spinal anaesthetic at the end of intrathecal injection and for the general anaesthetic when the anaesthetist was happy for surgery to start. In the second clinical part of the study, the time from intrathecal administration to 'adequate surgical anaesthesia' (defined as adequate for start of a category-1 caesarean section) was estimated in 100 elective (category-4) caesarean sections. The median (IQR [range]) times (min:s) for spinal procedure, onset of spinal block and general anaesthesia were 2:56 (2:32-3:32 [1:22-3:50]), 5:56 (4:23-7:39 [2:9-13:32]) and 1:56 (1:39-2:9 [1:13-3:12]), respectively. The limiting factor in urgent spinal anaesthesia is the unpredictable time needed for adequate surgical block to develop. Anaesthesia © 2013 The Association of Anaesthetists of Great Britain and Ireland.

  13. On the Grothendieck rings of equivariant fusion categories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burciu, Sebastian, E-mail: sebastian.burciu@imar.ro

    2015-07-15

    In this paper, we describe a Mackey type decomposition for group actions on abelian categories. This allows us to define new Mackey functors which associates to any subgroup the K-theory of the corresponding equivariantized abelian category. In the case of an action by tensor autoequivalences, the Mackey functor at the level of Grothendieck rings has a Green functor structure. As an application we give a description of the Grothendieck rings of equivariantized fusion categories under group actions by tensor autoequivalences on graded fusion categories. In this settings, a new formula for the tensor product of any two simple objects ofmore » an equivariantized fusion category is given, simplifying the fusion formula from Burciu and Natale [J. Math. Phys. 54, 013511 (2013)].« less

  14. Double dissociation of semantic categories in Alzheimer's disease.

    PubMed

    Gonnerman, L M; Andersen, E S; Devlin, J T; Kempler, D; Seidenberg, M S

    1997-04-01

    Data that demonstrate distinct patterns of semantic impairment in Alzheimer's disease (AD) are presented. Findings suggest that while groups of mild-moderate patients may not display category specific impairments, some individual patients do show selective impairment of either natural kinds or artifacts. We present a model of semantic organization in which category specific impairments arise from damage to distributed features underlying different types of categories. We incorporate the crucial notions of intercorrelations and distinguishing features, allowing us to demonstrate (1) how category specific impairments can result from widespread damage and (2) how selective deficits in AD reflect different points in the progression of impairment. The different patterns of impairment arise from an interaction between the nature of the semantic categories and the progression of damage.

  15. Single-dose evaluation of safety, tolerability and pharmacokinetics of newly formulated hydromorphone immediate-release and hydrophilic matrix extended-release tablets in healthy Japanese subjects without co-administration of an opioid antagonist.

    PubMed

    Toyama, Kaoru; Uchida, Naoki; Ishizuka, Hitoshi; Sambe, Takehiko; Kobayashi, Shinichi

    2015-09-01

    This single dose, open-label study investigated the safety, tolerability and pharmacokinetics of single oral doses of newly formulated immediate-release (IR) and hydrophilic matrix extended-release (ER) hydromorphone tablets in healthy Japanese subjects without co-administration of an opioid antagonist under fasting and fed conditions. Plasma and urinary concentrations of hydromorphone and metabolites were measured by liquid-chromatography tandem mass-spectroscopy. Following administration of the ER tablet, plasma concentrations of hydromorphone slowly increased with a median tmax of 5.0 h and the Cmax decreased to 37% of the IR tablet, while the AUC0-inf was comparable with that of the IR tablet when administered at the same dose. The degree of fluctuation in the plasma concentration for the ER tablet was much lower than that of the IR tablet and certain levels of plasma concentrations were maintained after 24 h of ER dosing. The AUC0-inf and Cmax increased with food for both IR and ER tablets. The AUC0-inf of hydromorphone-3-glucoside was one-tenth of that of hydromorphone-3-glucuronide. A single oral administration of the hydromorphone tablets would be well-tolerated in healthy Japanese subjects despite a lack of co-administration of an opioid antagonist and the newly developed ER hydromorphone tablets may have the appropriate PK characteristics for once-daily dosing. © 2015, The American College of Clinical Pharmacology.

  16. Statistical Inference in the Learning of Novel Phonetic Categories

    ERIC Educational Resources Information Center

    Zhao, Yuan

    2010-01-01

    Learning a phonetic category (or any linguistic category) requires integrating different sources of information. A crucial unsolved problem for phonetic learning is how this integration occurs: how can we update our previous knowledge about a phonetic category as we hear new exemplars of the category? One model of learning is Bayesian Inference,…

  17. 14 CFR 29.81 - Landing distance: Category A.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Landing distance: Category A. 29.81 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.81 Landing distance: Category A... knots for water landings) from a point 50 ft above the landing surface must be determined from the...

  18. 14 CFR 29.81 - Landing distance: Category A.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Landing distance: Category A. 29.81 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.81 Landing distance: Category A... knots for water landings) from a point 50 ft above the landing surface must be determined from the...

  19. 5 CFR 2504.4 - Determining if an individual is the subject of a record.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Determining if an individual is the subject of a record. 2504.4 Section 2504.4 Administrative Personnel OFFICE OF ADMINISTRATION, EXECUTIVE OFFICE OF THE PRESIDENT PRIVACY ACT REGULATIONS § 2504.4 Determining if an individual is the subject of a record. (a) Individuals desiring to know if ...

  20. 7 CFR 352.3 - Enforcement and administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... administration. (a) Plants, plant products, plant pests, noxious weeds, soil, and other products and articles... pests, noxious weeds, soil, or other products or articles in violation of this part will be subject to... of plants, plant products, plant pests, noxious weeds, soil, or other products or articles subject to...

  1. 7 CFR 352.3 - Enforcement and administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... administration. (a) Plants, plant products, plant pests, noxious weeds, soil, and other products and articles... pests, noxious weeds, soil, or other products or articles in violation of this part will be subject to... of plants, plant products, plant pests, noxious weeds, soil, or other products or articles subject to...

  2. 7 CFR 352.3 - Enforcement and administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... administration. (a) Plants, plant products, plant pests, noxious weeds, soil, and other products and articles... pests, noxious weeds, soil, or other products or articles in violation of this part will be subject to... of plants, plant products, plant pests, noxious weeds, soil, or other products or articles subject to...

  3. 7 CFR 352.3 - Enforcement and administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... administration. (a) Plants, plant products, plant pests, noxious weeds, soil, and other products and articles... pests, noxious weeds, soil, or other products or articles in violation of this part will be subject to... of plants, plant products, plant pests, noxious weeds, soil, or other products or articles subject to...

  4. Mere exposure alters category learning of novel objects.

    PubMed

    Folstein, Jonathan R; Gauthier, Isabel; Palmeri, Thomas J

    2010-01-01

    We investigated how mere exposure to complex objects with correlated or uncorrelated object features affects later category learning of new objects not seen during exposure. Correlations among pre-exposed object dimensions influenced later category learning. Unlike other published studies, the collection of pre-exposed objects provided no information regarding the categories to be learned, ruling out unsupervised or incidental category learning during pre-exposure. Instead, results are interpreted with respect to statistical learning mechanisms, providing one of the first demonstrations of how statistical learning can influence visual object learning.

  5. Mere Exposure Alters Category Learning of Novel Objects

    PubMed Central

    Folstein, Jonathan R.; Gauthier, Isabel; Palmeri, Thomas J.

    2010-01-01

    We investigated how mere exposure to complex objects with correlated or uncorrelated object features affects later category learning of new objects not seen during exposure. Correlations among pre-exposed object dimensions influenced later category learning. Unlike other published studies, the collection of pre-exposed objects provided no information regarding the categories to be learned, ruling out unsupervised or incidental category learning during pre-exposure. Instead, results are interpreted with respect to statistical learning mechanisms, providing one of the first demonstrations of how statistical learning can influence visual object learning. PMID:21833209

  6. Administrators' and Faculty Members' Perceptions of the Performance Appraisal Interview.

    ERIC Educational Resources Information Center

    McDowell, Earl E.

    An exploratory study examined how administrators (department heads/chairs) perceive faculty members, as well as themselves, in the performance appraisal interview. Subjects, 450 faculty members and 200 administrators at a midwestern university, answered an Appraisal Interview Questionnaire in which they rated administrator performance, content and…

  7. The Linguistic Construction of Social Categories in Toddlers

    ERIC Educational Resources Information Center

    Diesendruck, Gil; Deblinger-Tangi, Ronit

    2014-01-01

    Kindergarteners treat certain social categories as natural kinds. This study addressed how children pick out social categories. Ninety-one 19-and 26-month-olds were familiarized to exemplars of categories of people (e.g., Blacks-Whites, men-women) and animals (e.g., cows-horses). Participants then saw a picture matching the familiarization…

  8. Comparing English, Mandarin, and Russian Hydrographic and Terrain Categories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feng, Chen-Chieh; Sorokine, Alexandre

    The paper compares hydrographic and terrain categories in the geospatial data standards of the US, Taiwan, and Russian Federation where the dominant languages used are from di erent language families. It aims to identify structural and semantic di erences between similar categories across three geospatial data standards. By formalizing the data standard structures and identifying the properties that di erentiate sibling categories in each geospatial data standard using well-known formal relations and quality universals, we develop a common basis on which hydrographic and terrain categories in the three data standards can be compared. The result suggests that all three datamore » standards structure categories with a mixture of relations with di erent meaning even though most of them are well-known relations in top-level ontologies. Similar categories can be found across all three standards but exact match between similar categories are rare.« less

  9. From Statistics to Meaning: Infants’ Acquisition of Lexical Categories

    PubMed Central

    Lany, Jill; Saffran, Jenny R.

    2013-01-01

    Infants are highly sensitive to statistical patterns in their auditory language input that mark word categories (e.g., noun and verb). However, it is unknown whether experience with these cues facilitates the acquisition of semantic properties of word categories. In a study testing this hypothesis, infants first listened to an artificial language in which word categories were reliably distinguished by statistical cues (experimental group) or in which these properties did not cue category membership (control group). Both groups were then trained on identical pairings between the words and pictures from two categories (animals and vehicles). Only infants in the experimental group learned the trained associations between specific words and pictures. Moreover, these infants generalized the pattern to include novel pairings. These results suggest that experience with statistical cues marking lexical categories sets the stage for learning the meanings of individual words and for generalizing meanings to new category members. PMID:20424058

  10. Cross-Classification and Category Representation in Children's Concepts

    ERIC Educational Resources Information Center

    Nguyen, Simone P.

    2007-01-01

    Items commonly belong to many categories. Cross-classification is the classification of a single item into more than one category. This research explored 2- to 6-year-old children's use of 2 different category systems for cross-classification: script (e.g., school-time items, birthday party items) and taxonomic (e.g., animals, clothes). The…

  11. Quantum Bianchi identities via DG categories

    NASA Astrophysics Data System (ADS)

    Beggs, Edwin J.; Majid, Shahn

    2018-01-01

    We use DG categories to derive analogues of the Bianchi identities for the curvature of a connection in noncommutative differential geometry. We also revisit the Chern-Connes pairing but following the line of Chern's original derivation. We show that a related DG category of extendable bimodule connections is a monoidal tensor category and in the metric compatible case obtain an analogue of a classical antisymmetry of the Riemann tensor. The monoidal structure implies the existence of a cup product on noncommutative sheaf cohomology. Another application shows that the curvature of a line module reduces to a 2-form on the base algebra. We illustrate the theory on the q-sphere, the permutation group S3 and the bicrossproduct quantum spacetime [ r , t ] = λr.

  12. Uncovering contrast categories in categorization with a probabilistic threshold model.

    PubMed

    Verheyen, Steven; De Deyne, Simon; Dry, Matthew J; Storms, Gert

    2011-11-01

    A contrast category effect on categorization occurs when the decision to apply a category term to an entity not only involves a comparison between the entity and the target category but is also influenced by a comparison of the entity with 1 or more alternative categories from the same domain as the target. Establishing a contrast category effect on categorization in natural language categories has proven to be laborious, especially when the categories concerned are natural kinds situated at the superordinate level of abstraction. We conducted 3 studies with these categories to look for an influence on categorization of both similarity to the target category and similarity to a contrast category. The results are analyzed with a probabilistic threshold model that assumes categorization decisions arise from the placement of threshold criteria by individual categorizers along a single scale that holds the experimental stimuli. The stimuli's positions along the scale are shown to be influenced by similarity to both target and contrast. These findings suggest that the prevalence of contrast category effects on categorization might have been underestimated. Additional analyses demonstrate how the proposed model can be employed in future studies to systematically investigate the origins of contrast category effects on categorization.

  13. Category-Specific Neural Oscillations Predict Recall Organization During Memory Search

    PubMed Central

    Morton, Neal W.; Kahana, Michael J.; Rosenberg, Emily A.; Baltuch, Gordon H.; Litt, Brian; Sharan, Ashwini D.; Sperling, Michael R.; Polyn, Sean M.

    2013-01-01

    Retrieved-context models of human memory propose that as material is studied, retrieval cues are constructed that allow one to target particular aspects of past experience. We examined the neural predictions of these models by using electrocorticographic/depth recordings and scalp electroencephalography (EEG) to characterize category-specific oscillatory activity, while participants studied and recalled items from distinct, neurally discriminable categories. During study, these category-specific patterns predict whether a studied item will be recalled. In the scalp EEG experiment, category-specific activity during study also predicts whether a given item will be recalled adjacent to other same-category items, consistent with the proposal that a category-specific retrieval cue is used to guide memory search. Retrieved-context models suggest that integrative neural circuitry is involved in the construction and maintenance of the retrieval cue. Consistent with this hypothesis, we observe category-specific patterns that rise in strength as multiple same-category items are studied sequentially, and find that individual differences in this category-specific neural integration during study predict the degree to which a participant will use category information to organize memory search. Finally, we track the deployment of this retrieval cue during memory search: Category-specific patterns are stronger when participants organize their responses according to the category of the studied material. PMID:22875859

  14. Easing the Transition to School: Administrators' Descriptions of Transition to School Activities

    ERIC Educational Resources Information Center

    Noel, Andrea

    2011-01-01

    This paper details the early childhood transition activities of three schools in southern Queensland, Australia, as reported by school administrators. The transition programs were analysed using the categories of the Transition to School Matrix of the New South Wales (NSW) Department of Education. Activities fell into the first four categories…

  15. A Developmental Examination of the Conceptual Structure of Animal, Artifact, and Human Social Categories across Two Cultural Contexts

    ERIC Educational Resources Information Center

    Rhodes, Marjorie; Gelman, Susan A.

    2009-01-01

    Previous research indicates that the ontological status that adults attribute to categories varies systematically by domain. For example, adults view distinctions between different animal species as natural and objective, but view distinctions between different kinds of furniture as more conventionalized and subjective. The present work (N=435;…

  16. When does fading enhance perceptual category learning?

    PubMed

    Pashler, Harold; Mozer, Michael C

    2013-07-01

    Training that uses exaggerated versions of a stimulus discrimination (fading) has sometimes been found to enhance category learning, mostly in studies involving animals and impaired populations. However, little is known about whether and when fading facilitates learning for typical individuals. This issue was explored in 7 experiments. In Experiments 1 and 2, observers discriminated stimuli based on a single sensory continuum (time duration and line length, respectively). Adaptive fading dramatically improved performance in training (unsurprisingly) but did not enhance learning as assessed in a final test. The same was true for nonadaptive linear fading (Experiment 3). However, when variation in length (predicting category membership) was embedded among other (category-irrelevant) variation, fading dramatically enhanced not only performance in training but also learning as assessed in a final test (Experiments 4 and 5). Fading also helped learners to acquire a color saturation discrimination amid category-irrelevant variation in hue and brightness, although this learning proved transitory after feedback was withdrawn (Experiment 7). Theoretical implications are discussed, and we argue that fading should have practical utility in naturalistic category learning tasks, which involve extremely high dimensional stimuli and many irrelevant dimensions. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  17. The Effect of Response Scale, Administration Mode, and Format on Responses to the CAHPS Clinician and Group Survey

    PubMed Central

    Drake, Keith M; Hargraves, J Lee; Lloyd, Stephanie; Gallagher, Patricia M; Cleary, Paul D

    2014-01-01

    Objective To examine how different response scales, methods of survey administration, and survey format affect responses to the CAHPS (Consumer Assessment of Healthcare Providers and Systems) Clinician and Group (CG-CAHPS) survey. Study Design A total of 6,500 patients from a university health center were randomly assigned to receive the following: standard 12-page mail surveys using 4-category or 6-category response scales (on CG-CAHPS composite items), telephone surveys using 4-category or 6-category response scales, or four-page mail surveys. Principal Findings A total of 3,538 patients completed surveys. Composite score means and provider-level reliabilities did not differ between respondents receiving 4-category or 6-category response scale surveys or between 12-page and four-page mail surveys. Telephone respondents gave more positive responses than mail respondents. Conclusions We recommend using 4-category response scales and the four-page mail CG-CAHPS survey. PMID:24471975

  18. Prototypes and particulars: geometric and experience-dependent spatial categories.

    PubMed

    Spencer, John P; Hund, Alycia M

    2002-03-01

    People use geometric cues to form spatial categories. This study investigated whether people also use the spatial distribution of exemplars. Adults pointed to remembered locations on a tabletop. In Experiment 1, a target was placed in each geometric category, and the location of targets was varied. Adults' responses were biased away from a midline category boundary toward geometric prototypes located at the centers of left and right categories. Experiment 2 showed that prototype effects were not influenced by cross-category interactions. In Experiment 3, subsets of targets were positioned at different locations within each category. When prototype effects were removed, there was a bias toward the center of the exemplar distribution, suggesting that common categorization processes operate across spatial and object domains.

  19. The use of language and its impact on energy policy discourse: A case study of the hydrogen economy and the news media during the G.W. Bush administration

    NASA Astrophysics Data System (ADS)

    Waegel, Alexander Francis

    The development of policy is subject to many different influences. The subjects are often complex and citizens must rely on information provided by third parties in order to participate in the discussion. The news media has traditionally been the primary provider of such information and are counted upon to publish unbiased accounts of events. However, the news media gets information from its own sources and this offers an opportunity for powerful, well-organized groups to influence the presentation of these topics. This is done through the creation and dissemination of constructed narratives, which remove the contexts from facts to present different conclusions (Barthes, 1957). Sourcing discusses how the news media may be influenced by powerful organizations providing free, easily published material (Herman, 1988). The 24 hour news cycle, the demand for ratings, and the impossibility of funding independent research journalism for every topic requires them to seek information from sources viewed as reliable and authoritative, such as the government or major corporations. The wealthier and more powerful organizations are better able to provide this large quantity of information in a readily publishable format and thus have the potential to influence the presentation to reflect positively on their positions. As a technologically and politically complex subject, energy policy would be particularly prone to the influence of sourcing. Hydrogen energy was used as a case study to search for the presence of sourcing. Hydrogen fuels cells offer potential for the reduction of greenhouse gasses and other benefits, but have significant disadvantages as well. While the academic community remained divided on the technology, the G.W. Bush administration offered it unwavering support. The Bush administration and the academic community both released a great deal of information about hydrogen but each set presented a very different outlook. Articles, press releases, and speeches from

  20. An Eye-Tracking Study of Multiple Feature Value Category Structure Learning: The Role of Unique Features

    PubMed Central

    Liu, Zhiya; Song, Xiaohong; Seger, Carol A.

    2015-01-01

    We examined whether the degree to which a feature is uniquely characteristic of a category can affect categorization above and beyond the typicality of the feature. We developed a multiple feature value category structure with different dimensions within which feature uniqueness and typicality could be manipulated independently. Using eye tracking, we found that the highest attentional weighting (operationalized as number of fixations, mean fixation time, and the first fixation of the trial) was given to a dimension that included a feature that was both unique and highly typical of the category. Dimensions that included features that were highly typical but not unique, or were unique but not highly typical, received less attention. A dimension with neither a unique nor a highly typical feature received least attention. On the basis of these results we hypothesized that subjects categorized via a rule learning procedure in which they performed an ordered evaluation of dimensions, beginning with unique and strongly typical dimensions, and in which earlier dimensions received higher weighting in the decision. This hypothesis accounted for performance on transfer stimuli better than simple implementations of two other common theories of category learning, exemplar models and prototype models, in which all dimensions were evaluated in parallel and received equal weighting. PMID:26274332

  1. An Eye-Tracking Study of Multiple Feature Value Category Structure Learning: The Role of Unique Features.

    PubMed

    Liu, Zhiya; Song, Xiaohong; Seger, Carol A

    2015-01-01

    We examined whether the degree to which a feature is uniquely characteristic of a category can affect categorization above and beyond the typicality of the feature. We developed a multiple feature value category structure with different dimensions within which feature uniqueness and typicality could be manipulated independently. Using eye tracking, we found that the highest attentional weighting (operationalized as number of fixations, mean fixation time, and the first fixation of the trial) was given to a dimension that included a feature that was both unique and highly typical of the category. Dimensions that included features that were highly typical but not unique, or were unique but not highly typical, received less attention. A dimension with neither a unique nor a highly typical feature received least attention. On the basis of these results we hypothesized that subjects categorized via a rule learning procedure in which they performed an ordered evaluation of dimensions, beginning with unique and strongly typical dimensions, and in which earlier dimensions received higher weighting in the decision. This hypothesis accounted for performance on transfer stimuli better than simple implementations of two other common theories of category learning, exemplar models and prototype models, in which all dimensions were evaluated in parallel and received equal weighting.

  2. Age of acquisition affects the retrieval of grammatical category information.

    PubMed

    Bai, Lili; Ma, Tengfei; Dunlap, Susan; Chen, Baoguo

    2013-01-01

    This study investigated age of acquisition (AoA) effects on processing grammatical category information of Chinese single-character words. In Experiment 1, nouns and verbs that were acquired at different ages were used as materials in a grammatical category decision task. Results showed that the grammatical category information of earlier acquired nouns and verbs was easier to retrieve. In Experiment 2, AoA and predictability from orthography to grammatical category were manipulated in a grammatical category decision task. Results showed larger AoA effects under lower predictability conditions. In Experiment 3, a semantic category decision task was used with the same materials as those in Experiment 2. Different results were found from Experiment 2, suggesting that the grammatical category decision task is not merely the same as the semantic category decision task, but rather involves additional processing of grammatical category information. Therefore the conclusions of Experiments 1 and 2 were strengthened. In summary, it was found for the first time that AoA affects the retrieval of grammatical category information, thus providing new evidence in support of the arbitrary mapping hypothesis.

  3. 14 CFR 415.53 - Payloads not subject to review.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Payloads not subject to review. 415.53 Section 415.53 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... Communications Commission (FCC) or the Department of Commerce, National Oceanic and Atmospheric Administration...

  4. 14 CFR 415.53 - Payloads not subject to review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Payloads not subject to review. 415.53 Section 415.53 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... Communications Commission (FCC) or the Department of Commerce, National Oceanic and Atmospheric Administration...

  5. 14 CFR 415.53 - Payloads not subject to review.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Payloads not subject to review. 415.53 Section 415.53 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... Communications Commission (FCC) or the Department of Commerce, National Oceanic and Atmospheric Administration...

  6. 14 CFR 415.53 - Payloads not subject to review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Payloads not subject to review. 415.53 Section 415.53 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... Communications Commission (FCC) or the Department of Commerce, National Oceanic and Atmospheric Administration...

  7. 14 CFR 415.53 - Payloads not subject to review.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Payloads not subject to review. 415.53 Section 415.53 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... Communications Commission (FCC) or the Department of Commerce, National Oceanic and Atmospheric Administration...

  8. Trace of the Twisted Heisenberg Category

    NASA Astrophysics Data System (ADS)

    Oğuz, Can Ozan; Reeks, Michael

    2017-12-01

    We show that the trace decategorification, or zeroth Hochschild homology, of the twisted Heisenberg category defined by Cautis and Sussan is isomorphic to a quotient of {W^-}, a subalgebra of W_{1+∞} defined by Kac, Wang, and Yan. Our result is a twisted analogue of that by Cautis, Lauda, Licata, and Sussan relating W_{1+∞} and the trace decategorification of the Heisenberg category.

  9. Uncovering Contrast Categories in Categorization with a Probabilistic Threshold Model

    ERIC Educational Resources Information Center

    Verheyen, Steven; De Deyne, Simon; Dry, Matthew J.; Storms, Gert

    2011-01-01

    A contrast category effect on categorization occurs when the decision to apply a category term to an entity not only involves a comparison between the entity and the target category but is also influenced by a comparison of the entity with 1 or more alternative categories from the same domain as the target. Establishing a contrast category effect…

  10. Mefloquine pharmacokinetics in healthy subjects and in peptic ulcer patients after cimetidine administration.

    PubMed

    Kolawole, J A; Mustapha, A; Abudu-Aguye, I; Ochekpe, N

    2000-01-01

    The pharmacokinetics of orally administered mefloquine were determined in six healthy male subjects and in six ulcer patients before and after a 3-day course of cimetidine (400 mg morning and evening). Peak plasma concentrations Cmax and AUC0-infinity were similarly and significantly (P < 0.05) increased after cimetidine pretreatement in both healthy subjects and peptic ulcer patients Cmax was increased by 42.4% and 20.5% while AUC0-infinity was increased by 37.5% in healthy and peptic ulcer subjects respectively. The values of t1/2ab absorption and t1/2 beta elimination, total crearance CLT/F and volume of distribution were altered to varying levels after cimetidine treatment but the changes were not statistically significant in both healthy and peptic ulcer subjects. The established long t1/2 beta and this apparent interaction between mefloquine and cimetidine which resulted in increased mefloquine plasma concentration might be of clinical significant in patients with neurological/psychiatric history.

  11. Categorical perception of color: evidence from secondary category boundary

    PubMed Central

    Al-rasheed, Abdulrahman Saud

    2015-01-01

    Despite a plethora of behavioral research exploring the phenomenon of color categorical perception (CP) known as “better discrimination between pair of colors stimuli from different categories and pair of colors stimuli from the same category even when the stimulus differences between the pairs of stimuli are equal”, most of the evidence for the CP of color was derived from Roman or top-to-down script readers and very rarely from right-to-left script readers in primary category. To date, no studies of color CP have been conducted on right-to-left script readers in secondary category boundary to support this theory. Three experiments have been conducted: Experiments 1 and 2 established the Arabic blue–purple secondary category boundary, and Experiment 3 tested the CP of color in the blue–purple category boundary. Sixty participants (30 men and 30 women) took part in this study. All spoke Arabic as their first language, and all were undergraduate or postgraduate students at King Saud University. Their ages ranged from 18–35 years with a mean age of 21.9 years (SD =5.2). The result indicated that for Experiments 1 and 2, it appeared that the Arabic blue–purple category boundary was approximately 10PB and it is in the same location as for English. For Experiment 3, reaction times in the between-categories condition were significantly faster than those in the within-category condition; this suggested that CP of color was shown in the Arabic’s blue–purple secondary category boundary. PMID:26648764

  12. The role of semantic complexity in treatment of naming deficits: training semantic categories in fluent aphasia by controlling exemplar typicality.

    PubMed

    Kiran, Swathi; Thompson, Cynthia K

    2003-06-01

    The effect of typicality of category exemplars on naming was investigated using a single subject experimental design across participants and behaviors in 4 patients with fluent aphasia. Participants received a semantic feature treatment to improve naming of either typical or atypical items within semantic categories, while generalization was tested to untrained items of the category. The order of typicality and category trained was counterbalanced across participants. Results indicated that patients trained on naming of atypical exemplars demonstrated generalization to naming of intermediate and typical items. However, patients trained on typical items demonstrated no generalized naming effect to intermediate or atypical examples. Furthermore, analysis of errors indicated an evolution of errors throughout training, from those with no apparent relationship to the target to primarily semantic and phonemic paraphasias. Performance on standardized language tests also showed changes as a function of treatment. Theoretical and clinical implications regarding the impact of considering semantic complexity on rehabilitation of naming deficits in aphasia are discussed.

  13. The role of semantic complexity in treatment of naming deficits: training semantic categories in fluent aphasia by controlling exemplar typicality.

    PubMed

    Kiran, Swathi; Thompson, Cynthia K

    2003-08-01

    The effect of typicality of category exemplars on naming was investigated using a single subject experimental design across participants and behaviors in 4 patients with fluent aphasia. Participants received a semantic feature treatment to improve naming of either typical or atypical items within semantic categories, while generalization was tested to untrained items of the category. The order of typicality and category trained was counterbalanced across participants. Results indicated that patients trained on naming of atypical exemplars demonstrated generalization to naming of intermediate and typical items. However, patients trained on typical items demonstrated no generalized naming effect to intermediate or atypical examples. Furthermore, analysis of errors indicated an evolution of errors throughout training, from those with no apparent relationship to the target to primarily semantic and phonemic paraphasias. Performance on standardized language tests also showed changes as a function of treatment. Theoretical and clinical implications regarding the impact of considering semantic complexity on rehabilitation of naming deficits in aphasia are discussed.

  14. Into the Sunset: Reflections of an Interim Administrator.

    ERIC Educational Resources Information Center

    Marlowe, John

    2000-01-01

    One advantage to an interim administrative position is that the public cuts short-timers a little slack. Temporary administrators can learn on the job and become experts on specialized subjects. Personnel issues demand more time than interims possess. Such positions usually do not turn into long-term contracts. (MLH)

  15. Correspondence between Grammatical Categories and Grammatical Functions in Chinese.

    ERIC Educational Resources Information Center

    Tan, Fu

    1993-01-01

    A correspondence is shown between grammatical categories and grammatical functions in Chinese. Some syntactic properties distinguish finite verbs from nonfinite verbs, nominals from other categories, and verbs from other categories. (Contains seven references.) (LB)

  16. Multimedia category preferences of working engineers

    NASA Astrophysics Data System (ADS)

    Baukal, Charles E.; Ausburn, Lynna J.

    2016-09-01

    Many have argued for the importance of continuing engineering education (CEE), but relatively few recommendations were found in the literature for how to use multimedia technologies to deliver it most effectively. The study reported here addressed this gap by investigating the multimedia category preferences of working engineers. Four categories of multimedia, with two types in each category, were studied: verbal (text and narration), static graphics (drawing and photograph), dynamic non-interactive graphics (animation and video), and dynamic interactive graphics (simulated virtual reality (VR) and photo-real VR). The results showed that working engineers strongly preferred text over narration and somewhat preferred drawing over photograph, animation over video, and simulated VR over photo-real VR. These results suggest that a variety of multimedia types should be used in the instructional design of CEE content.

  17. Very Early Administration of Progesterone Does Not Improve Neuropsychological Outcomes in Subjects with Moderate to Severe Traumatic Brain Injury.

    PubMed

    Goldstein, Felicia C; Caveney, Angela F; Hertzberg, Vicki S; Silbergleit, Robert; Yeatts, Sharon D; Palesch, Yuko Y; Levin, Harvey S; Wright, David W

    2017-01-01

    A Phase III, double-blind, placebo-controlled trial (ProTECT III) found that administration of progesterone did not reduce mortality or improve functional outcome as measured by the Glasgow Outcome Scale Extended (GOSE) in subjects with moderate to severe traumatic brain injury. We conducted a secondary analysis of neuropsychological outcomes to evaluate whether progesterone is associated with improved recovery of cognitive and motor functioning. ProTECT III was conducted at 49 level I trauma centers in the United States. Adults with moderate to severe TBI were randomized to receive intravenous progesterone or placebo within 4 h of injury for a total of 4 days. At 6 months, subjects underwent evaluation of memory, attention, executive functioning, language, and fine motor coordination/dexterity. Chi-square analysis revealed no significant difference in the proportion of subjects (263/280 progesterone, 283/295 placebo) with Galveston Orientation and Amnesia Test scores ≥75. Analyses of covariance did not reveal significant treatment effects for memory (Buschke immediate recall, p = 0.53; delayed recall, p = 0.94), attention (Trails A speed, p = 0.81 and errors, p = 0.22; Digit Span Forward length, p = 0.66), executive functioning (Trails B speed, p = 0.97 and errors, p = 0.93; Digit Span Backward length, p = 0.60), language (timed phonemic fluency, p = 0.05), and fine motor coordination/dexterity (Grooved Pegboard dominant hand time, p = 0.75 and peg drops, p = 0.59; nondominant hand time, p = 0.74 and peg drops, p = 0.61). Pearson Product Moment Correlations demonstrated significant (p < 0.001) associations between better neuropsychological performance and higher GOSE scores. Similar to the ProTECT III trial's results of the primary outcome, the secondary outcomes do not provide evidence of a neuroprotective effect of progesterone.

  18. Very Early Administration of Progesterone Does Not Improve Neuropsychological Outcomes in Subjects with Moderate to Severe Traumatic Brain Injury

    PubMed Central

    Caveney, Angela F.; Hertzberg, Vicki S; Silbergleit, Robert; Yeatts, Sharon D.; Palesch, Yuko Y.; Levin, Harvey S.; Wright, David W.

    2017-01-01

    Abstract A Phase III, double-blind, placebo-controlled trial (ProTECT III) found that administration of progesterone did not reduce mortality or improve functional outcome as measured by the Glasgow Outcome Scale Extended (GOSE) in subjects with moderate to severe traumatic brain injury. We conducted a secondary analysis of neuropsychological outcomes to evaluate whether progesterone is associated with improved recovery of cognitive and motor functioning. ProTECT III was conducted at 49 level I trauma centers in the United States. Adults with moderate to severe TBI were randomized to receive intravenous progesterone or placebo within 4 h of injury for a total of 4 days. At 6 months, subjects underwent evaluation of memory, attention, executive functioning, language, and fine motor coordination/dexterity. Chi-square analysis revealed no significant difference in the proportion of subjects (263/280 progesterone, 283/295 placebo) with Galveston Orientation and Amnesia Test scores ≥75. Analyses of covariance did not reveal significant treatment effects for memory (Buschke immediate recall, p = 0.53; delayed recall, p = 0.94), attention (Trails A speed, p = 0.81 and errors, p = 0.22; Digit Span Forward length, p = 0.66), executive functioning (Trails B speed, p = 0.97 and errors, p = 0.93; Digit Span Backward length, p = 0.60), language (timed phonemic fluency, p = 0.05), and fine motor coordination/dexterity (Grooved Pegboard dominant hand time, p = 0.75 and peg drops, p = 0.59; nondominant hand time, p = 0.74 and peg drops, p = 0.61). Pearson Product Moment Correlations demonstrated significant (p < 0.001) associations between better neuropsychological performance and higher GOSE scores. Similar to the ProTECT III trial's results of the primary outcome, the secondary outcomes do not provide evidence of a neuroprotective effect of progesterone. PMID:26973025

  19. Caffeine withdrawal symptoms and self-administration following caffeine deprivation.

    PubMed

    Mitchell, S H; de Wit, H; Zacny, J P

    1995-08-01

    This study examined the effects of complete or partial caffeine deprivation on withdrawal symptomatology and self-administration of coffee in caffeine-dependent coffee drinkers. Nine habitual coffee drinkers abstained from dietary sources of caffeine for 33.5 h. Caffeine deprivation was manipulated by administering capsules containing 0%, 50%, or 100% of each subject's daily caffeine intake (complete, partial, and no deprivation conditions). Caffeine withdrawal symptomatology was measured using self-report questionnaires. Caffeine self-administration was measured using: i) the amount of coffee subjects earned on a series of concurrent random-ratio schedules that yielded coffee and money reinforcers; ii) the amount of earned coffee they consumed. Saliva samples revealed that subjects complied with the caffeine abstinence instructions. Caffeine withdrawal symptoms occurred reliably following complete caffeine deprivation, though not in the partial deprivation condition. Caffeine self-administration was not related to deprivation condition. We conclude that caffeine withdrawal symptomatology is not necessarily associated with increased caffeine consumption.

  20. Acute administration of capsaicin increases resting energy expenditure in young obese subjects without affecting energy intake, appetite, and circulating levels of orexigenic/anorexigenic peptides.

    PubMed

    Rigamonti, Antonello E; Casnici, Claudia; Marelli, Ornella; De Col, Alessandra; Tamini, Sofia; Lucchetti, Elisa; Tringali, Gabriella; De Micheli, Roberta; Abbruzzese, Laura; Bortolotti, Mauro; Cella, Silvano G; Sartorio, Alessandro

    2018-04-01

    Although capsaicin has been reported to reduce energy intake and increase energy expenditure in an adult (normal weight or overweight) population, thus resulting in a net negative energy balance and weight loss, these beneficial effects have not been investigated in young obese subjects. We hypothesize that capsaicin acutely administered in young obese subjects exerts the same effects on energy balance and that these effects are mediated by changes in gastrointestinal peptides regulating appetite. Thus, the aim of the present study was to evaluate the acute effects of capsaicin (2 mg) or placebo on energy intake, hunger, and satiety in obese adolescents and young adults (female-male ratio: 4:6, age: 21.0 ± 5.8 years; body mass index: 41.5 ± 4.3 kg/m 2 ) provided an ad libitum dinner. Furthermore, circulating levels of some orexigenic (ghrelin) and anorexigenic (glucagon-like peptide 1 and peptide YY) peptides were measured after a meal completely consumed (lunch), together with the evaluation of hunger and satiety and assessment of resting energy expenditure (REE) through indirect computerized calorimetry. When compared to placebo, capsaicin did not significantly change either energy intake or hunger/satiety 6 hours after its administration (dinner). No differences in circulating levels of ghrelin, glucagon-like peptide 1, and peptide YY and in hunger/satiety were found in the 3 hours immediately after food ingestion among obese subjects treated with capsaicin or placebo (lunch). By contrast, the meal significantly increased REE in the capsaicin- but not placebo-treated group (capsaicin: from 1957.2 ± 455.1 kcal/d up to 2342.3 ± 562.1 kcal/d, P < .05; placebo: from 2060.1 ± 483.4 kcal/d up to 2296.0 ± 484.5 kcal/d). The pre-post meal difference in REE after capsaicin administration was significantly higher than that observed after placebo (385.1 ± 164.4 kcal/d vs 235.9 ± 166.1 kcal/d, P < .05). In conclusion, although capsaicin does not exert hypophagic

  1. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where the...) Chapter 1-43 of the Department Grants Administration Manual 2 068 concerning animal welfare. 2 See...

  2. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where the...) Chapter 1-43 of the Department Grants Administration Manual 2 068 concerning animal welfare. 2 See...

  3. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where the...) Chapter 1-43 of the Department Grants Administration Manual 2 068 concerning animal welfare. 2 See...

  4. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where the...) Chapter 1-43 of the Department Grants Administration Manual 2 068 concerning animal welfare. 2 See...

  5. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where the...) Chapter 1-43 of the Department Grants Administration Manual 2 068 concerning animal welfare. 2 See...

  6. National Survey of Professional, Administrative, Technical, and Clerical Pay, March 1977. Bulletin 1980.

    ERIC Educational Resources Information Center

    Bureau of Labor Statistics (DOL), Washington, DC.

    This publication summarizes results of the Bureau of Labor Statistics' 18th annual salary survey of selected professional, administrative, technical, and clerical occupations in private industry as of March 1977. The survey provides nationwide salary averages (not including Alaska and Hawaii) and distributions for 78 work-level categories covering…

  7. The Role of Corticostriatal Systems in Speech Category Learning

    PubMed Central

    Yi, Han-Gyol; Maddox, W. Todd; Mumford, Jeanette A.; Chandrasekaran, Bharath

    2016-01-01

    One of the most difficult category learning problems for humans is learning nonnative speech categories. While feedback-based category training can enhance speech learning, the mechanisms underlying these benefits are unclear. In this functional magnetic resonance imaging study, we investigated neural and computational mechanisms underlying feedback-dependent speech category learning in adults. Positive feedback activated a large corticostriatal network including the dorsolateral prefrontal cortex, inferior parietal lobule, middle temporal gyrus, caudate, putamen, and the ventral striatum. Successful learning was contingent upon the activity of domain-general category learning systems: the fast-learning reflective system, involving the dorsolateral prefrontal cortex that develops and tests explicit rules based on the feedback content, and the slow-learning reflexive system, involving the putamen in which the stimuli are implicitly associated with category responses based on the reward value in feedback. Computational modeling of response strategies revealed significant use of reflective strategies early in training and greater use of reflexive strategies later in training. Reflexive strategy use was associated with increased activation in the putamen. Our results demonstrate a critical role for the reflexive corticostriatal learning system as a function of response strategy and proficiency during speech category learning. Keywords: category learning, fMRI, corticostriatal systems, speech, putamen PMID:25331600

  8. A Bulk Microphysics Parameterization with Multiple Ice Precipitation Categories.

    NASA Astrophysics Data System (ADS)

    Straka, Jerry M.; Mansell, Edward R.

    2005-04-01

    A single-moment bulk microphysics scheme with multiple ice precipitation categories is described. It has 2 liquid hydrometeor categories (cloud droplets and rain) and 10 ice categories that are characterized by habit, size, and density—two ice crystal habits (column and plate), rimed cloud ice, snow (ice crystal aggregates), three categories of graupel with different densities and intercepts, frozen drops, small hail, and large hail. The concept of riming history is implemented for conversions among the graupel and frozen drops categories. The multiple precipitation ice categories allow a range of particle densities and fall velocities for simulating a variety of convective storms with minimal parameter tuning. The scheme is applied to two cases—an idealized continental multicell storm that demonstrates the ice precipitation process, and a small Florida maritime storm in which the warm rain process is important.

  9. The Effect of Cumin cyminum L. Plus Lime Administration on Weight Loss and Metabolic Status in Overweight Subjects: A Randomized Double-Blind Placebo-Controlled Clinical Trial

    PubMed Central

    Taghizadeh, Mohsen; Memarzadeh, Mohammad Reza; Abedi, Fatemeh; Sharifi, Nasrin; Karamali, Fatemeh; Fakhrieh Kashan, Zohreh; Asemi, Zatollah

    2016-01-01

    Background Limited data are available regarding the effects of combined administration of Cumin cyminum L. and lime on weight loss and metabolic profiles among subjects with overweight subjects. Objectives The current study aimed to assess the effects of combined administration of Cumin cyminum L. and lime on weight loss and metabolic profiles among subjects with overweight. Patients and Methods This randomized double-blind placebo-controlled clinical trial was conducted on 72 subjects with overweight, aged 18 - 50 years old. Participants were randomly divided into three groups: Group A received high-dose Cumin cyminum L. and lime capsules (75 mg each, n = 24), group B low-dose Cumin cyminum L. and lime capsules (25 mg each, n = 24) and group C placebos (n = 24) twice daily for eight weeks. Results After eight weeks of intervention, compared with low-dose C. cyminum L. plus lime and placebo, taking high-dose C. cyminum L. plus lime resulted in significant weight loss (in the high-dose group: -2.1 ± 1.7 vs. in the low-dose group: -1.2 ± 1.5 and in the placebo group: + 0.2 ± 1.3 kg, respectively; P < 0.001) and body mass index (-0.8 ± 0.6 vs. -0.5 ± 0.5 and +0.1 ± 0.5 kg/m2, respectively; P < 0.001). In addition, administration of high-dose C. cyminum L. plus lime compared with low-dose C. cyminum L. plus lime and placebo, led to a significant reduction in fasting plasma glucose (FPG) (P < 0.001) and a significant rise in quantitative insulin sensitivity check index (QUICKI) (+ 0.02 ± 0.02 vs. + 0.01 ± 0.02 and 0.01 ± 0.01, respectively; P = 0.01). Moreover, a significant decrease in serum triglycerides (-14.1 ± 56.2 vs. +13.9 ± 36.8 and + 10.6 ± 25.1 mg/dL; respectively; P = 0.03), total-cholesterol (-18.4 ± 28.6 vs. +8.6 ± 28.5 and -1.0 ± 24.8 mg/dL; respectively; P = 0.004) and low density lipoproteins- (LDL)-cholesterol levels (-11.8 ± 20.7 vs. +6.5 ± 23.2 and -2.9 ± 20.4 mg/dL, respectively; P = 0.01) was observed following the consumption of

  10. The role of human drug self-administration procedures in the development of medications

    PubMed Central

    Comer, SD; Ashworth, JB; Foltin, RW; Johanson, CE; Zacny, JP; Walsh, SL

    2008-01-01

    The purpose of this review is to illustrate the utility and value of employing human self-administration procedures in medication development, including abuse liability assessments of novel medications and evaluation of potential pharmacotherapies for substance use disorders. Traditionally, human abuse liability testing has relied primarily on subjective reports describing drug action by use of questionnaires; similarly, drug interactions between putative treatment agents and the drugs of abuse have relied on these measures. Subjective reports are highly valued because they provide qualitative and quantitative information about the characteristics of central and peripheral pharmacodynamic effects as well as safety and tolerability. However, self-administration procedures directly examine the behavior of interest – that is, drug taking. The present paper 1) reviews the most commonly used human self-administration procedures, 2) discusses the concordance of subjective reports and self-administration within the context of medications development for substance use disorders, focusing primarily on illustrative examples from development efforts with opioid and cocaine dependence, and 3) explores the utility of applying self-administration procedures to assess the abuse liability of novel compounds, including “abuse deterrent” formulations (ADFs). The review will focus on opioid and cocaine dependence because a rich database from both clinical laboratory and clinical trial research exists for these two drug classes. The data reviewed suggest that drug-induced changes in self-administration and subjective effects are not always concordant. Therefore, assessment of self-administration in combination with subjective effects provides a more comprehensive picture that may have improved predictive validity for translating to the clinical setting. PMID:18436394

  11. Effect of between-category similarity on basic-level superiority in pigeons

    PubMed Central

    Lazareva, Olga F.; Soto, Fabián A.; Wasserman, Edward A.

    2010-01-01

    Children categorize stimuli at the basic level faster than at the superordinate level. We hypothesized that between-category similarity may affect this basic-level superiority effect. Dissimilar categories may be easy to distinguish at the basic level but be difficult to group at the superordinate level, whereas similar categories may be easy to group at the superordinate level but be difficult to distinguish at the basic level. Consequently, similar basic-level categories may produce a superordinate-before-basic learning trend, whereas dissimilar basic-level categories may result in a basic-before-superordinate learning trend. We tested this hypothesis in pigeons by constructing superordinate-level categories out of basic-level categories with known similarity. In Experiment 1, we experimentally evaluated the between-category similarity of four basic-level photographic categories using multiple fixed interval-extinction training (Astley & Wasserman, 1992). We used the resultant similarity matrices in Experiment 2 to construct two superordinate-level categories from basic-level categories with high between-category similarity (cars and persons; chairs and flowers). We then trained pigeons to concurrently classify those photographs into either the proper basic-level category or the proper superordinate-level category. Under these conditions, the pigeons learned the superordinate-level discrimination faster than the basic-level discrimination, confirming our hypothesis that basic-level superiority is affected by between-category similarity. PMID:20600696

  12. 39 CFR 3002.11 - Administrative Office.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administrative Officer the incumbent head is also responsible, subject to the policy guidelines of the Commission..., the physical reading room, and the library on the premises of the Commission's offices, as well as the...

  13. Generalized Categorial Grammar for Unbounded Dependencies Recovery

    ERIC Educational Resources Information Center

    Nguyen, Luan Viet

    2014-01-01

    Accurate recovery of predicate-argument dependencies is vital for interpretation tasks like information extraction and question answering, and unbounded dependencies may account for a significant portion of the dependencies in any given text. This thesis describes a Generalized Categorial Grammar (GCG) which, like other categorial grammars,…

  14. Self-report captures 27 distinct categories of emotion bridged by continuous gradients.

    PubMed

    Cowen, Alan S; Keltner, Dacher

    2017-09-19

    Emotions are centered in subjective experiences that people represent, in part, with hundreds, if not thousands, of semantic terms. Claims about the distribution of reported emotional states and the boundaries between emotion categories-that is, the geometric organization of the semantic space of emotion-have sparked intense debate. Here we introduce a conceptual framework to analyze reported emotional states elicited by 2,185 short videos, examining the richest array of reported emotional experiences studied to date and the extent to which reported experiences of emotion are structured by discrete and dimensional geometries. Across self-report methods, we find that the videos reliably elicit 27 distinct varieties of reported emotional experience. Further analyses revealed that categorical labels such as amusement better capture reports of subjective experience than commonly measured affective dimensions (e.g., valence and arousal). Although reported emotional experiences are represented within a semantic space best captured by categorical labels, the boundaries between categories of emotion are fuzzy rather than discrete. By analyzing the distribution of reported emotional states we uncover gradients of emotion-from anxiety to fear to horror to disgust, calmness to aesthetic appreciation to awe, and others-that correspond to smooth variation in affective dimensions such as valence and dominance. Reported emotional states occupy a complex, high-dimensional categorical space. In addition, our library of videos and an interactive map of the emotional states they elicit (https://s3-us-west-1.amazonaws.com/emogifs/map.html) are made available to advance the science of emotion.

  15. NASA thesaurus alphabetical update: Subject terms for indexing scientific and technical information

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The NASA THESAURUS - ALPHABETICAL UPDATE is an alphabetical listing of all subject terms (postable and nonpostable) that are currently approved for use in the NASA scientific and technical information system. Contained in the listing are the subject terms that were listed in the Preliminary Edition of the NASA THESAURUS and the additional subject terms that were approved during the period January 1, 1967 June 30, 1971. Complete Thesaurus structuring, including scope notes, category assignments, and cross-references, is provided for each term as appropriate.

  16. Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population.

    PubMed

    Yang, Tubao; Walker, Mark C; Krewski, Daniel; Yang, Qiuying; Nimrod, Carl; Garner, Peter; Fraser, William; Olatunbosun, Olufemi; Wen, Shi Wu

    2008-03-01

    To estimate the frequency of exposure to prescription Food and Drug Administration (FDA) category C, D, and X drugs in pregnant women, and to analyze the maternal characteristics associated with such an exposure. A 50% random sample of women who gave a birth in Saskatchewan between January 1, 1997 and December 31, 2000 was chosen for the study. The rate of exposure to FDA category C, D, or X drugs recorded in the pharmacist database was estimated. Associations of exposure to FDA category C, D, and X drugs with maternal characteristics were evaluated using multiple logistical regression, with adjusted odds ratios (ORs) and its 95% confidence intervals (CIs) as the association measures. A total of 18 575 women were included in this study. Among them, 3604 (19.4%) had exposure to one or more FDA category C, D, and X drugs during pregnancy. Category C drugs were the most frequently used drugs (15.8%), followed by D drugs (5.2%), and X drugs (3.9%). Women with chronic health conditions had fourfold at increased risk of exposure than women without. Regardless of health status, women who were <20 years of age, who had a parity > or =3, and who were on social assistance plan were at increased risk of pregnancy exposure to these drugs. About 19.4% pregnant women are exposed to FDA C, D or X drugs during pregnancy. Women with chronic diseases, younger age, increased parity, and under social assistance are at increased risk of exposure to FDA C, D, or X drugs. Copyright 2008 John Wiley & Sons, Ltd.

  17. Association between family history risk categories and prevalence of diabetes in Chinese population.

    PubMed

    Zhang, Jinping; Yang, Zhaojun; Xiao, Jianzhong; Xing, Xiaoyan; Lu, Juming; Weng, Jianping; Jia, Weiping; Ji, Linong; Shan, Zhongyan; Liu, Jie; Tian, Haoming; Ji, Qiuhe; Zhu, Dalong; Ge, Jiapu; Chen, Li; Guo, Xiaohui; Zhao, Zhigang; Li, Qiang; Zhou, Zhiguang; Lin, Lixiang; Wang, Na; Yang, Wenying

    2015-01-01

    To investigate the association between different family history risk categories and prevalence of diabetes in the Chinese population. The family history of diabetes was obtained from each subject, and an oral glucose tolerance test was performed for measuring the fasting and postload glucose and insulin levels based on a national representative cross-sectional survey of 46,239 individuals (age ≥ 20 years) in the 2007-2008 China National Diabetes and Metabolism Disorders Study. The family history risk categories of diabetes were high, moderate, and average (FH2 and FH1: at least two generations and one generation of first-degree relatives with diabetes, respectively; FH0: no first-degree relatives with diabetes). The age- and gender-adjusted prevalence rates of diabetes were 32.7% (95% confidence interval (CI): 26.4-39.7%) in FH2, 20.1% (95% CI: 18.2-22.1%) in FH1, and 8.4% (95% CI: 7.9-8.9%) in FH0 (P < 0.0001). The calculated homeostatic model assessment-estimated insulin resistance (HOMA-IR), Matsuda insulin sensitivity index (ISI), and insulinogenic index (ΔI30/ΔG30) values showed significant trending changes among the three risk categories, with the most negative effects in FH2. Multivariate logistic regression analysis showed that the odds ratios of having diabetes were 6.16 (95% CI: 4.46-8.50) and 2.86 (95% CI: 2.41-3.39) times higher in FH2 and FH1, respectively, than in FH0 after adjustment for classical risk factors for diabetes. Family history risk categories of diabetes have a significant, independent, and graded association with the prevalence of this disease in the Chinese population.

  18. 40 CFR 125.81 - Who is subject to this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Who is subject to this subpart? 125.81 Section 125.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS... coastal subcategories of the oil and gas extraction point source category as defined under 40 CFR 435.10...

  19. 40 CFR 125.81 - Who is subject to this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Who is subject to this subpart? 125.81 Section 125.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS... coastal subcategories of the oil and gas extraction point source category as defined under 40 CFR 435.10...

  20. 40 CFR 125.81 - Who is subject to this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Who is subject to this subpart? 125.81 Section 125.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS... coastal subcategories of the oil and gas extraction point source category as defined under 40 CFR 435.10...