Science.gov

Sample records for administration-orange county regulatory

  1. 75 FR 29559 - The 13th Annual Food and Drug Administration-Orange County Regulatory Affairs Educational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... HUMAN SERVICES Food and Drug Administration The 13th Annual Food and Drug Administration-Orange County...-sponsored with the Orange County Regulatory Affairs Discussion Group (OCRA). The conference is intended to...-608-4417; or Orange County Regulatory Affairs Discussion Group ] (OCRA), Attention to Detail,...

  2. 76 FR 19373 - The 14th Annual Food and Drug Administration-Orange County Regulatory Affairs Educational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... HUMAN SERVICES Food and Drug Administration The 14th Annual Food and Drug Administration-Orange County... announcing the following conference: 14th Annual Educational Conference co-sponsored with the Orange County...: 949-608-4417; or Orange County Regulatory Affairs Discussion Group, Attention to Detail,...

  3. 77 FR 24721 - The 15th Annual Food and Drug Administration-Orange County Regulatory Affairs Educational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration The 15th Annual Food and Drug Administration--Orange County... announcing the following conference: The 15th Annual Educational Conference cosponsored with the...

  4. Environmental regulatory compliance plan, Deaf County site, Texas: Draft revision 1

    SciTech Connect

    Not Available

    1987-12-14

    The DOE is committed to conduct its operation in an environmentally safe and sound manner and comply with the letter and spirit of applicable environmental statues and regulations. These objectives are codified in DOE order N 5400.2, ''Environmental Policy Statement.'' This document, the Deaf Smith County site (Texas) Environmental Regulatory Compliance Plam (ERCP), is one means of implementing that policy. The ERCP describes the environmental regulatory requirements applicable to the Deaf Smith County site (Texas), and presented the framework within which the Salt Repository Project Office (SRPO) will comply with the requirements. The plan also discusses how DOE will address State and local environmental requirements. To achieve this purpose the ERCP will be developed in phases. This version of the ERCP is the first phase in the delopment of the ERCP. It represents the Salt Repository Project Office's understanding of environmental requirements for the site characterization phase of repository development. After consultation with the appropriate federal and state agencies and affected Indian tribes, the ERCP will be updated to reflect the results of consultation with these agencies and affected Indian tribes. 6 refs., 38 figs.

  5. 76 FR 13172 - Placer County Water Agency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Energy Regulatory Commission Placer County Water Agency Notice of Application Tendered for Filing with... Filed: February 23, 2011 d. Applicant: Placer County Water Agency e. Name of Project: Middle Fork... Manager, Placer County Water Agency, 144 Ferguson Road, Auburn, CA 95603; Telephone: (530) 823-4490....

  6. Dunn-Nokota methanol project, Dunn County, North Dakota. Volume VI. Tax, legal and regulatory analysis. [Proposed methanol project near Dunn Center, North Dakota

    SciTech Connect

    Not Available

    1982-01-01

    The objective of the Tax, Legal and Regulatory Analysis section of the study was to evaluate the basic tax, legal and regulatory premises upon which the Project and other parts of the study are based. The major part of these analyses concern federal income tax principles affecting the construction of a large-scale alternative energy project, particularly the application of the investment and energy tax credits, the recovery of costs through depreciation, treatment of pre-construction expenditures, capitalization of real property construction period interest, and leasing and project organization principles. Portions of the tax analysis were revised after their completion because of the passage in late August of the Tax Equity and Fiscal Responsibility Act of 1982 (the 1982 Tax Act), which makes important changes in the law. North Dakota state principles are also discussed. The balance of the legal report deals with non-income tax and tariff matters, permit requirements, federal coal leasing principles, prehistory and cultural resources, legal title to the project site, Federal Clean Air Act considerations, and other regulatory matters.

  7. 78 FR 41390 - Pershing County Water Conservation District; Notice of Application Tendered for Filing with the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Pershing County Water Conservation District; Notice of Application Tendered...: Pershing County Water Conservation District. e. Name of Project: Humboldt River Hydro Power Project....

  8. 75 FR 38798 - Douglas County, OR; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... Energy Regulatory Commission Douglas County, OR; Notice of Preliminary Permit Application Accepted for..., 2010, Douglas County, Oregon, filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power Act, proposing to study the feasibility of the Douglas County Wave and...

  9. 77 FR 12830 - Pershing County Water Conservation District; Notice of Intent To File License Application, Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Energy Regulatory Commission Pershing County Water Conservation District; Notice of Intent To File....: 14327-000. c. Date Filed: November 22, 2011. d. Submitted by: Pershing County Water Conservation... Applicant Contact: Bennie Hodges, Pershing County Water Conservation District, P.O. Box 218, Lovelock,...

  10. 78 FR 28897 - Lost Creek ISR, LLC, Lost Creek Uranium In-Situ Recovery Project; Sweetwater County, Wyoming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Lost Creek ISR, LLC, Lost Creek Uranium In-Situ Recovery Project; Sweetwater County, Wyoming AGENCY: Nuclear Regulatory Commission. ACTION: Environmental assessment and finding of no...

  11. DRAFT LANDSAT DATA MOSAIC: MONTGOMERY COUNTY, TEXAS; HARRIS COUNTY, TEXAS; FORT BEND COUNTY, TEXAS; BRAZORIA COUNTY, TEXAS; GALVESTON COUNTY, TEXAS

    EPA Science Inventory

    This is a draft Landsat Data Mosaic, which contains remote sensing information for Montgomery County, Texas Harris County, Texas Fort Bend County, Texas Brazoria County, Texas Galveston County, and Texas Imagery dates on the following dates: October 6, 1999 and September 29, 200...

  12. Regulatory Anatomy

    PubMed Central

    2015-01-01

    This article proposes the term “safety logics” to understand attempts within the European Union (EU) to harmonize member state legislation to ensure a safe and stable supply of human biological material for transplants and transfusions. With safety logics, I refer to assemblages of discourses, legal documents, technological devices, organizational structures, and work practices aimed at minimizing risk. I use this term to reorient the analytical attention with respect to safety regulation. Instead of evaluating whether safety is achieved, the point is to explore the types of “safety” produced through these logics as well as to consider the sometimes unintended consequences of such safety work. In fact, the EU rules have been giving rise to complaints from practitioners finding the directives problematic and inadequate. In this article, I explore the problems practitioners face and why they arise. In short, I expose the regulatory anatomy of the policy landscape. PMID:26139952

  13. Regulatory RNAs

    PubMed Central

    Vazquez-Anderson, Jorge; Contreras, Lydia M

    2013-01-01

    RNAs have many important functional properties, including that they are independently controllable and highly tunable. As a result of these advantageous properties, their use in a myriad of sophisticated devices has been widely explored. Yet, the exploitation of RNAs for synthetic applications is highly dependent on the ability to characterize the many new molecules that continue to be discovered by large-scale sequencing and high-throughput screening techniques. In this review, we present an exhaustive survey of the most recent synthetic bacterial riboswitches and small RNAs while emphasizing their virtues in gene expression management. We also explore the use of these RNA components as building blocks in the RNA synthetic biology toolbox and discuss examples of synthetic RNA components used to rewire bacterial regulatory circuitry. We anticipate that this field will expand its catalog of smart devices by mimicking and manipulating natural RNA mechanisms and functions. PMID:24356572

  14. Regulatory Physiology

    NASA Technical Reports Server (NTRS)

    Lane, Helen W.; Whitson, Peggy A.; Putcha, Lakshmi; Baker, Ellen; Smith, Scott M.; Stewart, Karen; Gretebeck, Randall; Nimmagudda, R. R.; Schoeller, Dale A.; Davis-Street, Janis

    1999-01-01

    As noted elsewhere in this report, a central goal of the Extended Duration Orbiter Medical Project (EDOMP) was to ensure that cardiovascular and muscle function were adequate to perform an emergency egress after 16 days of spaceflight. The goals of the Regulatory Physiology component of the EDOMP were to identify and subsequently ameliorate those biochemical and nutritional factors that deplete physiological reserves or increase risk for disease, and to facilitate the development of effective muscle, exercise, and cardiovascular countermeasures. The component investigations designed to meet these goals focused on biochemical and physiological aspects of nutrition and metabolism, the risk of renal (kidney) stone formation, gastrointestinal function, and sleep in space. Investigations involved both ground-based protocols to validate proposed methods and flight studies to test those methods. Two hardware tests were also completed.

  15. 75 FR 40821 - Public Utility District No. 1 of Douglas County; Notice of Settlement Agreement and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... Energy Regulatory Commission Public Utility District No. 1 of Douglas County; Notice of Settlement...-2149-131. c. Date Filed: May 27, 2010. d. Applicant: Public Utility District No. 1 of Douglas County..., Douglas, and Okanogan Counties in central Washington. The project occupies 15.15 acres of Federal...

  16. 77 FR 34033 - Public Utility District No. 1 of Douglas County; Notice of Authorization for Continued Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Energy Regulatory Commission Public Utility District No. 1 of Douglas County; Notice of Authorization for Continued Project Operation On May 27, 2010, the Public Utility District No. 1 of Douglas County, licensee... on the Columbia River in Douglas, Okanogan, and Chelan Counties, Washington. The license for...

  17. 76 FR 71008 - Yuba County Water Agency; Notice of Dispute Resolution Process Schedule; Panel Meeting, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... Energy Regulatory Commission Yuba County Water Agency; Notice of Dispute Resolution Process Schedule... resolution process, pursuant to 18 CFR 5.14, in the relicensing proceeding for the Yuba County Water Agency's... dispute resolution panel member. On October 25, 2011, Commission staff designated Stephen P. Bowler...

  18. 78 FR 2984 - Antrim County; Notice of Application Tendered for Filing With the Commission, Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... Energy Regulatory Commission Antrim County; Notice of Application Tendered for Filing With the Commission.... Project No.: P-3030-019. c. Date filed: December 21, 2012. d. Applicant: Antrim County. e. Name of Project: Elk Rapids Hydroelectric Project f. Location: On the Elk River in the village of Elk Rapids in...

  19. 78 FR 59919 - Pershing County Water Conservation District; Notice of Application Accepted for Filing With the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... Energy Regulatory Commission Pershing County Water Conservation District; Notice of Application Accepted... County Water Conservation District. e. Name of Project: Humboldt River Hydropower Project. f. Location... water quality certification; (2) a copy of the request for certification, including proof of the date...

  20. 77 FR 2717 - Cherokee County Cogeneration Partners, LLC; Supplemental Notice That Initial Market-Based Rate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... Energy Regulatory Commission Cherokee County Cogeneration Partners, LLC; Supplemental Notice That Initial... notice in the above-referenced proceeding of Cherokee County Cogeneration Partners, LLC's application for... for review in the Commission's Public Reference Room in Washington, DC. There is an eSubscription...

  1. 75 FR 19632 - San Diego County Water Authority; Notice of Preliminary Permit Application Accepted for Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... Pumped Storage Water Power Project No. 13747. The proposed project would be located at the existing San... Energy Regulatory Commission San Diego County Water Authority; Notice of Preliminary Permit Application.... On March 1, 2010, San Diego County Water Authority filed an application for a preliminary...

  2. West front. The three small regulatory pumps to the right ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    West front. The three small regulatory pumps to the right of the building were installed ca. 1974-1975. Note electric substation towers in the background - Wellton-Mohawk Irrigation System, Pumping Plant No. 2, Bounded by Interstate 8 to south, Wellton, Yuma County, AZ

  3. County Staff or Area Staff?

    ERIC Educational Resources Information Center

    McIntyre, William J.

    1970-01-01

    McIntryre explores the questions of county-based extention and increased specialization in Indiana. He compares the multi-county with individual county systems using variables including clientele's reactions to the two systems. (NL)

  4. Current California legislative and regulatory activity impacting geothermal hydrothermal commercialization: monitoring report No. 2. Report No. 1020

    SciTech Connect

    Not Available

    1980-04-20

    The progress of four bills relating to geothermal energy is reported. The current regulatory activities of the California Energy Commission, the Lake County Planning Commission/Lake County Air Pollution Control District, the Governor's Office of Planning and Research, the State Lands' Commission, and the California Public Utilities Commission are reviewed. (MHR)

  5. 76 FR 70719 - Public Utility District No. 1 of Snohomish County; Notice of Intent To File License Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Snohomish County; Notice of Intent To File... Hydroelectric Project. f. Location: On Hancock Creek, in King County, Washington. No federal lands are...

  6. 76 FR 70719 - Public Utility District No. 1 of Snohomish County; Notice of Intent To File License Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Snohomish County; Notice of Intent To File... Hydroelectric Project. f. Location: On Calligan Creek, in King County, Washington. No federal lands are...

  7. 75 FR 81264 - Public Utility District No. 1 of Douglas County; Notice of Intent To Prepare an Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Douglas County; Notice of Intent To Prepare... of Douglas County filed an application for the continued operation of the 774.3-megawatt...

  8. 75 FR 51257 - Public Utility District No. 1 of Douglas County (Douglas PUD); Notice of Application Ready for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... Federal Energy Regulatory Commission Public Utility District No. 1 of Douglas County (Douglas PUD); Notice... District No. 1 of Douglas County (Douglas PUD). e. Name of Project: Wells Hydroelectric Project. f. Location: The existing project is located on the Columbia River in Douglas, Okanogan, and Chelan...

  9. 75 FR 33289 - Public Utility District No. 1 of Douglas County (Douglas PUD); Notice of Application Tendered for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... Federal Energy Regulatory Commission Public Utility District No. 1 of Douglas County (Douglas PUD); Notice... Utility District No. 1 of Douglas County (Douglas PUD). e. Name of Project: Wells Hydroelectric Project. f. Location: The existing project is located on the Columbia River in Douglas, Okanogan, and Chelan...

  10. 77 FR 66607 - Placer County Water Agency; Notice of Application for Approval of Contract for the Sale of Power...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Energy Regulatory Commission Placer County Water Agency; Notice of Application for Approval of Contract for the Sale of Power for a Period Extending Beyond the Term of the License Take notice that on July 17, 2012, Placer County Water Agency filed with the Commission an application for approval of:...

  11. 77 FR 14515 - Camden County Energy Recovery, Associates, L.P.; Supplemental Notice That Initial Market-Based...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... Energy Regulatory Commission Camden County Energy Recovery, Associates, L.P.; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for Blanket Section 204 Authorization This is a supplemental notice in the above-referenced proceeding of Camden County Energy Recovery Associates,...

  12. Environmental regulatory update table

    SciTech Connect

    Brown, K.J.; Langston, M.E.; Tucker, C.S.; Reed, R.M.

    1987-06-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  13. Nuclear Regulatory Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... agenda on April 26, 2010 (75 FR 21960). For this edition of the NRC's regulatory agenda, the most... publication of the last NRC semiannual agenda on April 26, 2010 (75 FR 21960). Within each group, the rules... regulations to improve the control over the distribution of source material to exempt persons and to...

  14. 77 FR 72968 - Revisions to the California State Implementation Plan, for Imperial County, Placer County and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... County and Ventura County Air Pollution Control Districts AGENCY: Environmental Protection Agency (EPA... Imperial County Air Pollution Control District (ICAPCD), Placer County Air Pollution Control District (PCAPCD) and Ventura County Air Pollution Control District (PCAPCD) portions of the California...

  15. Regulatory guidance document

    SciTech Connect

    1994-05-01

    The Office of Civilian Radioactive Waste Management (OCRWM) Program Management System Manual requires preparation of the OCRWM Regulatory Guidance Document (RGD) that addresses licensing, environmental compliance, and safety and health compliance. The document provides: regulatory compliance policy; guidance to OCRWM organizational elements to ensure a consistent approach when complying with regulatory requirements; strategies to achieve policy objectives; organizational responsibilities for regulatory compliance; guidance with regard to Program compliance oversight; and guidance on the contents of a project-level Regulatory Compliance Plan. The scope of the RGD includes site suitability evaluation, licensing, environmental compliance, and safety and health compliance, in accordance with the direction provided by Section 4.6.3 of the PMS Manual. Site suitability evaluation and regulatory compliance during site characterization are significant activities, particularly with regard to the YW MSA. OCRWM`s evaluation of whether the Yucca Mountain site is suitable for repository development must precede its submittal of a license application to the Nuclear Regulatory Commission (NRC). Accordingly, site suitability evaluation is discussed in Chapter 4, and the general statements of policy regarding site suitability evaluation are discussed in Section 2.1. Although much of the data and analyses may initially be similar, the licensing process is discussed separately in Chapter 5. Environmental compliance is discussed in Chapter 6. Safety and Health compliance is discussed in Chapter 7.

  16. Regulatory sequence analysis tools.

    PubMed

    van Helden, Jacques

    2003-07-01

    The web resource Regulatory Sequence Analysis Tools (RSAT) (http://rsat.ulb.ac.be/rsat) offers a collection of software tools dedicated to the prediction of regulatory sites in non-coding DNA sequences. These tools include sequence retrieval, pattern discovery, pattern matching, genome-scale pattern matching, feature-map drawing, random sequence generation and other utilities. Alternative formats are supported for the representation of regulatory motifs (strings or position-specific scoring matrices) and several algorithms are proposed for pattern discovery. RSAT currently holds >100 fully sequenced genomes and these data are regularly updated from GenBank.

  17. 3 CFR - Regulatory Review

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... been learned since that time. Far more is now known about regulation—not only about when it is... interests of future generations; identify methods of ensuring that regulatory review does not produce...

  18. Snohomish County Biodiesel Project

    SciTech Connect

    Chang, Terrill; Carveth, Deanna

    2010-02-01

    Snohomish County in western Washington State began converting its vehicle fleet to use a blend of biodiesel and petroleum diesel in 2005. As prices for biodiesel rose due to increased demand for this cleaner-burning fuel, Snohomish County looked to its farmers to grow this fuel locally. Suitable seed crops that can be crushed to extract oil for use as biodiesel feedstock include canola, mustard, and camelina. The residue, or mash, has high value as an animal feed. County farmers began with 52 acres of canola and mustard crops in 2006, increasing to 250 acres and 356 tons in 2008. In 2009, this number decreased to about 150 acres and 300 tons due to increased price for mustard seed.

  19. Assessing the regulatory picture

    SciTech Connect

    Not Available

    1994-02-01

    This article addresses the safety of the nation's drinking water supply and discusses compliance of the Clean Water Act. Right now, the shape of the regulatory future is uncertain. The results of the D-DBP regulatory negotiation are imminent. Congress is ready to begin debating reauthorization of the Safe Drinking Water Act, and utilities are trying to comply with the regulations while trying not to price water out of the reach of some of their customers.

  20. NRC regulatory initiatives

    SciTech Connect

    Johnson, T.C.

    1989-11-01

    The US Nuclear Regulatory Commission (NRC) is addressing several low-level waste disposal issues that will be important to waste generators and to States and Compacts developing new disposal capacity. These issues include Greater-Than-Class C (GTCC) waste, mixed waste, below regulatory concern (BRC) waste, and the low-level waste data base. This paper discusses these issues and their current status.

  1. Viral complement regulatory proteins.

    PubMed

    Rosengard, A M; Ahearn, J M

    1999-05-01

    The inactivation of complement provides cells and tissues critical protection from complement-mediated attack and decreases the associated recruitment of other inflammatory mediators. In an attempt to evade the host immune response, viruses have evolved two mechanisms to acquire complement regulatory proteins. They can directly seize the host cell complement regulators onto their outer envelope and/or they can produce their own proteins which are either secreted into the neighboring intercellular space or expressed as membrane-bound proteins on the infected host cell. The following review will concentrate on the viral homologues of the mammalian complement regulatory proteins, specifically those containing complement control protein (CCP) repeats. PMID:10408371

  2. Rationales for regulatory activity

    SciTech Connect

    Perhac, R.M.

    1997-02-01

    The author provides an outline which touches on the types of concerns about risk evaluation which are addressed in the process of establishing regulatory guides. Broadly he says regulatory activity serves three broad constituents: (1) Paternalism (private risk); (2) Promotion of social welfare (public risks); (3) Protection of individual rights (public risks). He then discusses some of the major issues encountered in reaching a decision on what is an acceptable level of risk within each of these areas, and how one establishes such a level.

  3. EPAct Transportation Regulatory Activities

    SciTech Connect

    2011-11-21

    The U.S. Department of Energy's (DOE) Vehicle Technologies Program manages several transportation regulatory activities established by the Energy Policy Act of 1992 (EPAct), as amended by the Energy Conservation Reauthorization Act of 1998, EPAct 2005, and the Energy Independence and Security Act of 2007 (EISA).

  4. The regulatory horizon

    NASA Technical Reports Server (NTRS)

    Cook, ED

    1987-01-01

    The author briefly discusses the FAA's position as it relates to cockpit resource management. For example, if Cockpit Resource Management (CRM) is a positive concept, why isn't everyone required to implement it? The regulatory practice of the FAA is discussed and questions and answers are presented.

  5. Mono County update

    SciTech Connect

    Lyster, D.L.

    1987-06-01

    On February 9, 1988, the Mono County Board of Supervisors voted to approve Bonneville Pacific Corporation's Mammoth Chance Geothermal Project. The project is an air-cooled, binary, geothermal power plant, 10 megawatts, net. The Mono County Board of Supervisors issued a project use-permit with vigorous and stringent conditions. Specific emphasis was placed on the establishment of a monitoring program designed to detect the effects of geothermal development on the springs at the Hot Creek Fish Hatchery and Hot Creek Gorge. On October 5, 1987, the Mono County Planning Commission granted a use-permit to Mammoth Pacific for its Mammoth Pacific II Project, a binary, air-cooled, geothermal power plant, 10 megawatts, net. The issuance of the use-permit instigated an appeal by the Sierra Club. That appeal was heard on February 22, 1988, At the end of the testimony, the Board of Supervisors voted to uphold the appeal of the Sierra Club, thereby denying the project by a vote of 3 to 2. The main areas of concern voiced by the majority of the Board included potential hydrologic impacts to Hot Creek Gorge and Hot Creek Fish Hatchery, visual impacts, and impacts to mule deer migration and survival. One of the options now available to Mammoth Pacific is to request that the project be denied without prejudice. This would allow Mammoth Pacific to return to the Board immediately with additional material regarding its concerns.

  6. 77 FR 73005 - Revisions to the California State Implementation Plan, Imperial County, Placer County, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... County, and Ventura County Air Pollution Control Districts AGENCY: Environmental Protection Agency (EPA... Pollution Control District (ICAPCD), Placer County Air Pollution Control District (PCAPCD) and Ventura County Air Pollution Control District (PCAPCD) portions of the California State Implementation Plan...

  7. Generalized Potentiometric Surface of the Arikaree Aquifer, Pine Ridge Indian Reservation and Bennett County, South Dakota

    USGS Publications Warehouse

    Carter, Janet M.; Heakin, Allen J.

    2007-01-01

    INTRODUCTION The Pine Ridge Indian Reservation and Bennett County are located in southwest South Dakota. The Pine Ridge Indian Reservation includes all of Shannon County and the part of Jackson County south of the White River. Extensive Indian trust lands are in Bennett County. For purposes of this map, the Pine Ridge Indian Reservation and all of Bennett County are included in the study area (sheet 1). Ground water from wells and springs is the predominant source of public and domestic supply within the study area. The Arikaree aquifer is the largest source of ground water throughout this area. The Oglala Sioux Tribe is developing a ground-water management plan designed to ?preserve, protect and maintain the quality of ground water for living and future members and non-members of the Oglala Sioux Indian Tribe within the internal and external boundaries of the Pine Ridge Reservation? (Michael Catches Enemy, Oglala Sioux Tribe Natural Resources Regulatory Agency, oral commun., 2007). Hydrologic information about the Arikaree aquifer is important to managing this resource. In 1998, the U.S. Geological Survey (USGS) began working in cooperation with the Oglala Sioux Tribe to develop a potentiometric map of the Arikaree aquifer in Jackson and Shannon Counties, with a primary component of that effort being a well inventory in those counties. In 2003, the study area was expanded to include Bennett County.

  8. 77 FR 47058 - Middle Fork American River Hydroelectric Project Placer County Water Agency; Notice of Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Middle Fork American River Hydroelectric Project Placer County Water Agency... comments on the draft environmental impact statement for the Middle Fork American River Project No....

  9. 78 FR 79427 - Greenwood County; Notice of Application Accepted for Filing and Soliciting Comments, Motions To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Greenwood County; Notice of Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Protests Take notice that the following hydroelectric application has been filed with the Commission and...

  10. 77 FR 27097 - LaCrosse Boiling Water Reactor, Exemption From Certain Requirements, Vernon County, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-08

    ... revised 10 CFR 73.55 through the issuance of a final rule on March 27, 2009 (74 FR 13926). Section 73.55... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION LaCrosse Boiling Water Reactor, Exemption From Certain Requirements, Vernon County, WI...

  11. 77 FR 70426 - Public Utility District No. 1 of Snohomish County, Washington; Notice of Revised Procedural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Snohomish County, Washington; Notice of Revised Procedural Schedule for Processing the License Application Based on the information in the record now, the Commission will...

  12. 78 FR 11754 - Approval and Promulgation of Implementation Plans; Tennessee: Knox County Supplement Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... County to account for changes in the emissions model and vehicle miles traveled (VMT) projection model... Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental...: Lynorae Benjamin, Chief, Regulatory Development Section, Air Planning Branch, Air, Pesticides and...

  13. 76 FR 72197 - Yuba County Water Agency; Notice of Panel Meeting and Technical Conference Details

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ... Energy Regulatory Commission Yuba County Water Agency; Notice of Panel Meeting and Technical Conference... anadromous fish: Sediment supply, transport, and storage; (5) large wood and riparian habitat for anadromous..., the dispute resolution panel convened. On November 9, 2011, the Commission issued a Notice of...

  14. 76 FR 78702 - Progress Energy Florida, Inc. (Combined License Application for Levy County Nuclear Power Plant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Progress Energy Florida, Inc. (Combined License Application for Levy County Nuclear Power Plant, Units 1 and 2) Notice of Atomic Safety and Licensing Board Reconstitution Pursuant to 10 CFR...

  15. Hydrology of Lake County, Florida

    USGS Publications Warehouse

    Knochenmus, Darwin D.; Hughes, G.H.

    1976-01-01

    Lake County includes a 1,150 square-mile area consisting of ridges, uplands, and valleys in central-peninsular Florida. About 32 percent of the county is covered by lakes, swamps, and marshes. Water requirements in 1970 averaged about 54 million gallons per day. About 85 percent of the water was obtained from wells; about 15 percent from lakes. The Floridan aquifer supplies almost all the ground water used in Lake County. Annual recharge to the Floridan aquifer averages about 7 inches over the county; runoff average 8.5 inches. The quality of ground and surface water in Lake County is in general good enough for most uses; however, the poor quality of Floridan-aquifer water in the St. John River Valley probably results from the upward movement of saline water along a fault zone. Surface water in Lake County is usually less mineralized than ground water but is more turbid and colored. (Woodard-USGS)

  16. Toxicogenomics and the Regulatory Framework

    EPA Science Inventory

    Toxicogenomics presents regulatory agencies with the opportunity to revolutionize their analyses by enabling the collection of information on a broader range of responses than currently considered in traditional regulatory decision making. Analyses of genomic responses are expec...

  17. Nuclear Regulatory Commission information digest

    SciTech Connect

    None,

    1990-03-01

    The Nuclear Regulatory Commission information digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the commission. This is an annual publication for the general use of the NRC Staff and is available to the public. The digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  18. 12 CFR 562.2 - Regulatory reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of the special supervisory, regulatory, and economic policy needs served by such reports. Regulatory... reflects the underlying economic substance of the transaction at issue. Regulatory reporting...

  19. 78 FR 44329 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ....nasa.gov/open . Timetable: Action Date FR Cite NPRM 10/00/13 Regulatory Flexibility Analysis Required... Administration (NASA). ACTION: Semiannual regulatory agenda. SUMMARY: NASA's regulatory agenda describes those regulations being considered for development or amendment by NASA, the need and legal basis for the...

  20. 75 FR 79759 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Action 04/16/10 75 FR 2012 Regulatory Flexibility Analysis Required: Yes Agency Contact: Mohammed Khan... ``Regulatory Planning and Review,'' 58 FR 51735, and the Regulatory Flexibility Act, 5 U.S.C. 601 et seq... use throughout the rulemaking process. Timetable: Action Date FR Cite Notice: Public Meeting...

  1. Establishing regulatory priorities

    SciTech Connect

    Pontius, F.W.

    1995-12-01

    Statutory deadlines for setting regulations under the 1986 Safe Drinking Water Act (SDWA) have not been met. Faced with limited resources, the US Environmental Protection Agency (USEPA) has historically set regulatory priorities based on perceived need, politics, and legal deadlines. This has resulted in a fragmented regulatory program and confusion on the part of the regulated community and on the part of other stakeholders. Even though the agency has been subject to court-imposed deadlines for most new regulations, resource limitations have caused these deadlines to be missed, resulting in new court-imposed deadlines. In 1994, the agency began considering a new approach for determining how many regulations can be developed and in what order. A draft strategic plan was prepared in December 1994. Based on discussion of this plan, USEPA requested the US District Court for Oregon to extend certain regulatory deadlines so that new priorities could be set for the highest-risk substances. An extension was granted until Aug. 1, 1995, and was subsequently extended to Dec. 15, 1995.

  2. Regulatory aspects on nanomedicines.

    PubMed

    Sainz, Vanessa; Conniot, João; Matos, Ana I; Peres, Carina; Zupancic, Eva; Moura, Liane; Silva, Liana C; Florindo, Helena F; Gaspar, Rogério S

    2015-12-18

    Nanomedicines have been in the forefront of pharmaceutical research in the last decades, creating new challenges for research community, industry, and regulators. There is a strong demand for the fast development of scientific and technological tools to address unmet medical needs, thus improving human health care and life quality. Tremendous advances in the biomaterials and nanotechnology fields have prompted their use as promising tools to overcome important drawbacks, mostly associated to the non-specific effects of conventional therapeutic approaches. However, the wide range of application of nanomedicines demands a profound knowledge and characterization of these complex products. Their properties need to be extensively understood to avoid unpredicted effects on patients, such as potential immune reactivity. Research policy and alliances have been bringing together scientists, regulators, industry, and, more frequently in recent years, patient representatives and patient advocacy institutions. In order to successfully enhance the development of new technologies, improved strategies for research-based corporate organizations, more integrated research tools dealing with appropriate translational requirements aiming at clinical development, and proactive regulatory policies are essential in the near future. This review focuses on the most important aspects currently recognized as key factors for the regulation of nanomedicines, discussing the efforts under development by industry and regulatory agencies to promote their translation into the market. Regulatory Science aspects driving a faster and safer development of nanomedicines will be a central issue for the next years.

  3. Equity and County College Financing.

    ERIC Educational Resources Information Center

    New Jersey State Commission on Financing Postsecondary Education, Trenton.

    An analysis by the Commission on Financial Postsecondary Education of the system by which New Jersey supports county colleges revealed disparities and inequities among the New Jersey counties in wealth and effort per full-time equivalent student, and current state financing practices that aggravate this problem. In response, alternative state…

  4. Frederick County Community Perception Survey.

    ERIC Educational Resources Information Center

    Frederick Community Coll., MD.

    In 1997, Frederick Community College (FCC) in Maryland conducted a telephone survey of a random sample of 466 Frederick County residents to identify their perceptions of the college. In particular, the survey examined Frederick County residents' image of FCC, level of awareness of services and programs offered by FCC, and the types of services…

  5. Topics for Lehigh County Seniors.

    ERIC Educational Resources Information Center

    Lehigh County Community Coll., Schnecksville, PA.

    Lehigh County Community College (Pennsylvania) and the Lehigh County Senior Citizens' Center collaborated on a project to assess the learning needs of the senior center's 1,600 members. A needs assessment completed by 68 center members and interviews of an additional 38 center members established that senior citizens preferred short-term workshops…

  6. Hydrology of Polk County, Florida

    USGS Publications Warehouse

    Spechler, Rick M.; Kroening, Sharon E.

    2007-01-01

    Local water managers usually rely on information produced at the State and regional scale to make water-resource management decisions. Current assessments of hydrologic and water-quality conditions in Polk County, Florida, commonly end at the boundaries of two water management districts (South Florida Water Management District and the Southwest Florida Water Management District), which makes it difficult for managers to determine conditions throughout the county. The last comprehensive water-resources assessment of Polk County was published almost 40 years ago. To address the need for current countywide information, the U.S. Geological Survey began a 3?-year study in 2002 to update information about hydrologic and water-quality conditions in Polk County and identify changes that have occurred. Ground-water use in Polk County has decreased substantially since 1965. In 1965, total ground-water withdrawals in the county were about 350 million gallons per day. In 2002, withdrawals totaled about 285 million gallons per day, of which nearly 95 percent was from the Floridan aquifer system. Water-conservation practices mainly related to the phosphate-mining industry as well as the decrease in the number of mines in operation in Polk County have reduced total water use by about 65 million gallons per day since 1965. Polk County is underlain by three principal hydrogeologic units. The uppermost water-bearing unit is the surficial aquifer system, which is unconfined and composed primarily of clastic deposits. The surficial aquifer system is underlain by the intermediate confining unit, which grades into the intermediate aquifer system and consists of up to two water-bearing zones composed of interbedded clastic and carbonate rocks. The lowermost hydrogeologic unit is the Floridan aquifer system. The Floridan aquifer system, a thick sequence of permeable limestone and dolostone, consists of the Upper Floridan aquifer, a middle semiconfining unit, a middle confining unit, and

  7. Toxicogenomics in regulatory ecotoxicology

    USGS Publications Warehouse

    Ankley, Gerald T.; Daston, George P.; Degitz, Sigmund J.; Denslow, Nancy D.; Hoke, Robert A.; Kennedy, Sean W.; Miracle, Ann L.; Perkins, Edward J.; Snape, Jason; Tillitt, Donald E.; Tyler, Charles R.; Versteeg, Donald

    2006-01-01

    Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has become a rapidly growing topical area in multiple biological disciplines. Since 1999, when the term “toxicogenomics” was coined to describe the application of genomics to toxicology (1), a rapid increase in publications on the topic has occurred (Figure 1). The potential utility of toxicogenomics in toxicological research and regulatory activities has been the subject of scientific discussions and, as with any new technology, has evoked a wide range of opinion (2–6). VIEWPOINT © 2006 american chemical Society july 1, 2006 / EnvironmEntal SciEncE & tEchnology n 4055 The purpose of this feature article is to consider the roles of toxicogenomics in the field of regulatory ecotoxicology, explore current limitations in the science and practice of genomics, and propose possible avenues to approach and resolve some of the major challenges. A significant amount of input to our analysis came from a workshop sponsored by the Society of Environmental Toxicology and Chemistry (SETAC) in Pellston, Mich., in September 2005. A complete list of names and affiliations of the experts participating in that workshop is provided online in Table 1 of the Supporting Information for this paper.

  8. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  9. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  10. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  11. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  12. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  13. Regulatory Considerations for Biosimilars

    PubMed Central

    Nellore, Ranjani

    2010-01-01

    Currently there is considerable interest in the legislative debate around generic biological drugs or “biosimilars” in the EU and US due to the large, lucrative market that it offers to the industry. While some countries have issued a few regulatory guidelines as well as product specific requirements, there is no general consensus as to a single, simple mechanism similar to the bioequivalence determination that leads to approval of generic small molecules all over the world. The inherent complex nature of the molecules, along with complicated manufacturing and analytical techniques to characterize them make it difficult to rely on a single human pharmacokinetic study for assurance of safety and efficacy. In general, the concept of comparability has been used for evaluation of the currently approved “similar” biological where a step by step assessment on the quality, preclinical and clinical aspects is made. In India, the focus is primarily on the availability and affordability of life-saving drugs. In this context every product needs to be evaluated on its own merit irrespective of the innovator brand. The formation of the National Biotechnology Regulatory Authority may provide a step in the right direction for regulation of these complex molecules. However, in order to have an efficient machinery for initial approval and ongoing oversight with a country-specific focus, cooperation with international authorities for granting approvals and continuous risk-benefit review is essential. Several steps are still needed for India to be perceived as a country that leads the world in providing quality biological products. PMID:21829775

  14. Regulatory Streamlining and Improvement

    SciTech Connect

    Mark A. Carl

    2006-07-11

    The Interstate Oil and Gas Compact Commission (IOGCC) engaged in numerous projects outlined under the scope of work discussed in the United States Department of Energy (DOE) grant number DE-FC26-04NT15456 awarded to the IOGCC. Numerous projects were completed that were extremely valuable to state oil and gas agencies as a result of work performed utilizing resources provided by the grant. There are numerous areas in which state agencies still need assistance. This additional assistance will need to be addressed under future scopes of work submitted annually to DOE's Project Officer for this grant. This report discusses the progress of the projects outlined under the grant scope of work for the 2005-2006 areas of interest, which are as follows: Area of Interest No. 1--Regulatory Streamlining and Improvement: This area of interest continues to support IOGCC's regulatory streamlining efforts that include the identification and elimination of unnecessary duplications of efforts between and among state and federal programs dealing with exploration and production on public lands. Area of Interest No. 2--Technology: This area of interest seeks to improve efficiency in states through the identification of technologies that can reduce costs. Area of Interest No. 3--Training and Education: This area of interest is vital to upgrading the skills of regulators and industry alike. Within the National Energy Policy, there are many appropriate training and education opportunities. Education was strongly endorsed by the President's National Energy Policy Development group. Acting through the governors offices, states are very effective conduits for the dissemination of energy education information. While the IOGCC favors the development of a comprehensive, long-term energy education plan, states are also supportive of immediate action on important concerns, such as energy prices, availability and conservation. Area of Interest No. 4--Resource Assessment and Development: This area

  15. Energy Improvements in Barnstable County

    SciTech Connect

    2003-09-01

    A fact sheet that describes Barnstable County, Massachusetts, effort to improve energy efficiency through a public appliance trade-in program, installation of compact fluorescent light bulbs in public buildings, and public energy education.

  16. Geothermal development plan: Yuma county

    SciTech Connect

    White, D.H.

    1981-01-01

    One hot spring and 33 wells drilled in the county discharge water at temperatures sufficient for direct-use geothermal applications such as process heat and space heating and cooling. Currently, one industry within the county has been identified which may be able to use geothermal energy for its process heat requirements. Also, a computer simulation model was used to predict geothermal energy on line as a function of time under both private and city-owned utility development of the resource.

  17. Geothermal Development Plan: Pima County

    SciTech Connect

    White, D.H.

    1981-01-01

    Pima County is located entirely within the Basin and Range physiographic province in which geothermal resources are known to occur. Continued growth as indicated by such factors as population growth, employment and income will require large amounts of energy. It is believed that geothermal energy could provide some of the energy that will be needed. Potential users of geothermal energy within the county are identified.

  18. 77 FR 7972 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... agenda pursuant to Executive Order 12866, ``Regulatory Planning and Review,'' 58 FR 51735, and the... Identifier No. 396 National Standards to 1105-AB34 Prevent, Detect, and Respond to Prison Rape (Reg Plan Seq... Prevent, Detect, and Respond to Prison Rape Regulatory Plan: This entry is Seq. No. 85 in part II of...

  19. 78 FR 1634 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... Administration (NASA). ACTION: Semiannual regulatory agenda. SUMMARY: NASA's regulatory agenda describes those regulations being considered for development or amendment by NASA, the need and legal basis for the actions... Controls and Management Systems, Office of Management Systems Division, NASA Headquarters, Washington,...

  20. 78 FR 1574 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... and stability to receive opioid addiction treatment medication. Timetable: Action Date FR Cite NPRM 06/19/09 74 FR 29153 NPRM Comment Period End 08/18/09 Final Action 12/06/12 77 FR 72752 Regulatory... FR Cite NPRM 03/00/13 Regulatory Flexibility Analysis Required: Yes. Agency Contact: Charles...

  1. Regulatory Foci and Organizational Commitment

    ERIC Educational Resources Information Center

    Markovits, Yannis; Ullrich, Johannes; van Dick, Rolf; Davis, Ann J.

    2008-01-01

    We use regulatory focus theory to derive specific predictions regarding the differential relationships between regulatory focus and commitment. We estimated a structural equation model using a sample of 520 private and public sector employees and found in line with our hypotheses that (a) promotion focus related more strongly to affective…

  2. 76 FR 11522 - In the Matter of Progress Energy Florida, Inc. (Combined License Application, Levy County Nuclear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION In the Matter of Progress Energy Florida, Inc. (Combined License Application, Levy County Nuclear Power Plant, Units 1 and 2); Notice of Appointment of Adjudicatory Employee Commissioners: Gregory...

  3. 77 FR 2974 - Yuba County Water Agency; Notice of Proposed Restricted Service List for a Programmatic Agreement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Yuba County Water Agency; Notice of Proposed Restricted Service List for a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the National Register of Historic Places Rule 2010 of...

  4. 75 FR 50930 - Final Determination To Approve Alternative Final Cover Request for the Lake County, Montana Landfill

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... contains a minimum of 6 inches of earthen material that is capable of sustaining native plant growth. The... approve in the Federal Register on February 10, 2010, (75 FR 6597) Lake County's site-specific flexibility... Executive Order Reviews Under Executive Order 12866, ``Regulatory Planning and Review'' (58 FR...

  5. 78 FR 4404 - Public Utility District No. 1 of Snohomish County, WA; Notice of Availability of Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... No. 486, 52 FR 47897), the Office of Energy Projects reviewed the Public Utility District No. 1 of... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Snohomish County, WA; Notice...

  6. 77 FR 55204 - Pubic Utility District No. 1 of Chelan County; Notice of Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Pubic Utility District No. 1 of Chelan County; Notice of Application... following hydroelectric application has been filed with the Commission and is available for...

  7. 77 FR 58821 - Public Utility District No. 1 of Chelan County; Notice of Application Accepted for Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Public Utility District No. 1 of Chelan County; Notice of Application... hydroelectric application has been filed with the Commission and is available for public inspection: a. Type...

  8. 75 FR 71467 - Exelon Nuclear Texas Holdings, LLC, Early Site Permit Application for the Victoria County Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ..., BWR Projects Branch, Division of New Reactor Licensing, Office of New Reactors, U.S. Nuclear... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Exelon Nuclear Texas Holdings, LLC, Early Site Permit Application for the Victoria County...

  9. T follicular regulatory cells.

    PubMed

    Sage, Peter T; Sharpe, Arlene H

    2016-05-01

    Pathogen exposure elicits production of high-affinity antibodies stimulated by T follicular helper (Tfh) cells in the germinal center reaction. Tfh cells provide both costimulation and stimulatory cytokines to B cells to facilitate affinity maturation, class switch recombination, and plasma cell differentiation within the germinal center. Under normal circumstances, the germinal center reaction results in antibodies that precisely target foreign pathogens while limiting autoimmunity and excessive inflammation. In order to have this degree of control, the immune system ensures Tfh-mediated B-cell help is regulated locally in the germinal center. The recently identified T follicular regulatory (Tfr) cell subset can migrate to the germinal center and inhibit Tfh-mediated B-cell activation and antibody production. Although many aspects of Tfr cell biology are still unclear, recent data have begun to delineate the specialized roles of Tfr cells in controlling the germinal center reaction. Here we discuss the current understanding of Tfr-cell differentiation and function and how this knowledge is providing new insights into the dynamic regulation of germinal centers, and suggesting more efficacious vaccine strategies and ways to treat antibody-mediated diseases.

  10. Internationalization of regulatory requirements.

    PubMed

    Juillet, Y

    2003-02-01

    The aim of harmonisation of medicines regulatory requirements is to allow the patient quicker access to new drugs and to avoid animal and human duplications. Harmonisation in the European Union (EU) is now completed, and has led to the submission of one dossier in one language study leading to European marketing authorizations, thanks in particular to efficacy guidelines published at the European level. With the benefit of the European experience since 1989, more than 40 guidelines have been harmonised amongst the EU, Japan and the USA through the International Conference on Harmonisation (ICH). ICH is a unique process gathering regulators and industry experts from the three regions. Its activity is built on expertise and trust. The Common Technical Document (CTD), an agreed common format for application in the three regions, is a logical follow-up to the ICH first phase harmonising the content of the dossier. The CTD final implementation in July 2003 will have considerable influence on the review process and on the exchange of information in the three regions.

  11. Current California legislative and regulatory activity impacting geothermal hydrothermal commercialization: a monitoring report. Report No. 1017

    SciTech Connect

    Not Available

    1980-01-20

    Four key geothermal-impacting bills presently before the California legislature are described. Two deal with state financial backing for geothermal projects. The third relates to the use of the state's share of the BLM geothermal revenues and the fourth to the protection of sensitive hot springs. The current regulatory activities of the California Energy Commission, the California Division of Oil and Gas, and the counties are discussed. (MHR)

  12. Healthcare regulatory concepts in Brazil.

    PubMed

    Oliveira, Robson Rocha de; Elias, Paulo Eduardo Mangeon

    2012-06-01

    The healthcare regulatory concepts used in Brazilian scientific publications on healthcare management were reviewed. A typo-logical classification for regulatory concepts was developed from the most current ideas in five disciplines: life sciences, law, economics, sociology and political science. Four ideas stood out: control, balance, adaptation and direction, with greatest emphasis on the technical nature of regulation. The political nature of regulation was secondary. It was considered that dis-cussion of healthcare regulatory concepts was connected with comprehension of the role that the state plays in this sector. De-finition of the forms of state intervention is the key convergence point between the different ways of conceptualizing healthcare regulation.

  13. Somerset County Flood Information System

    USGS Publications Warehouse

    Hoppe, Heidi L.

    2007-01-01

    The timely warning of a flood is crucial to the protection of lives and property. One has only to recall the floods of August 2, 1973, September 16 and 17, 1999, and April 16, 2007, in Somerset County, New Jersey, in which lives were lost and major property damage occurred, to realize how costly, especially in terms of human life, an unexpected flood can be. Accurate forecasts and warnings cannot be made, however, without detailed information about precipitation and streamflow in the drainage basin. Since the mid 1960's, the National Weather Service (NWS) has been able to forecast flooding on larger streams in Somerset County, such as the Raritan and Millstone Rivers. Flooding on smaller streams in urban areas was more difficult to predict. In response to this problem the NWS, in cooperation with the Green Brook Flood Control Commission, installed a precipitation gage in North Plainfield, and two flash-flood alarms, one on Green Brook at Seeley Mills and one on Stony Brook at Watchung, in the early 1970's. In 1978, New Jersey's first countywide flood-warning system was installed by the U.S. Geological Survey (USGS) in Somerset County. This system consisted of a network of eight stage and discharge gages equipped with precipitation gages linked by telephone telemetry and eight auxiliary precipitation gages. The gages were installed throughout the county to collect precipitation and runoff data that could be used to improve flood-monitoring capabilities and flood-frequency estimates. Recognizing the need for more detailed hydrologic information for Somerset County, the USGS, in cooperation with Somerset County, designed and installed the Somerset County Flood Information System (SCFIS) in 1990. This system is part of a statewide network of stream gages, precipitation gages, weather stations, and tide gages that collect data in real time. The data provided by the SCFIS improve the flood forecasting ability of the NWS and aid Somerset County and municipal agencies in

  14. Geothermal development plan: Yuma County

    SciTech Connect

    White, D.H.; Goldstone, L.A.

    1982-08-01

    The Yuma County Area Development Plan evaluated the county-wide market potential for utilizing geothermal energy. The study identified four potential geothermal resource areas with temperatures less than 90/sup 0/C (194/sup 0/F), and in addition, two areas are inferred to contain geothermal resources with intermediate (90/sup 0/C to 150/sup 0/C, 194/sup 0/F to 300/sup 0/F) temperature potential. The resource areas are isolated, although one resource area is located near Yuma, Arizona. One resource site is inferred to contain a hot dry rock resource. Anticipated population growth in the county is expected to be 2 percent per year over the next 40 years. The primary employment sector is agriculture, though some light industry is located in the county. Water supplies are found to be adequate to support future growth without advese affect on agriculture. Six firms were found in Yuma County which may be able to utilize geothermal energy for process heat needs. In addition, several agricultural processors were found, concentrated in citrus processing and livestock raising. Geothermal energy utilization projections suggest that by the year 2000, geothermal energy may economically provide the energy equivalent of 53,000 barrels of oil per year to the industrial sector if developed privately. Geothermal utilization projections increase to 132,000 barrels of oil per year by 2000 if a municipal utility developed the resource.

  15. Regulatory Snapshots: integrative mining of regulatory modules from expression time series and regulatory networks.

    PubMed

    Gonçalves, Joana P; Aires, Ricardo S; Francisco, Alexandre P; Madeira, Sara C

    2012-01-01

    Explaining regulatory mechanisms is crucial to understand complex cellular responses leading to system perturbations. Some strategies reverse engineer regulatory interactions from experimental data, while others identify functional regulatory units (modules) under the assumption that biological systems yield a modular organization. Most modular studies focus on network structure and static properties, ignoring that gene regulation is largely driven by stimulus-response behavior. Expression time series are key to gain insight into dynamics, but have been insufficiently explored by current methods, which often (1) apply generic algorithms unsuited for expression analysis over time, due to inability to maintain the chronology of events or incorporate time dependency; (2) ignore local patterns, abundant in most interesting cases of transcriptional activity; (3) neglect physical binding or lack automatic association of regulators, focusing mainly on expression patterns; or (4) limit the discovery to a predefined number of modules. We propose Regulatory Snapshots, an integrative mining approach to identify regulatory modules over time by combining transcriptional control with response, while overcoming the above challenges. Temporal biclustering is first used to reveal transcriptional modules composed of genes showing coherent expression profiles over time. Personalized ranking is then applied to prioritize prominent regulators targeting the modules at each time point using a network of documented regulatory associations and the expression data. Custom graphics are finally depicted to expose the regulatory activity in a module at consecutive time points (snapshots). Regulatory Snapshots successfully unraveled modules underlying yeast response to heat shock and human epithelial-to-mesenchymal transition, based on regulations documented in the YEASTRACT and JASPAR databases, respectively, and available expression data. Regulatory players involved in functionally enriched

  16. Geothermal development plan: Maricopa county

    SciTech Connect

    White, D.H.

    1981-01-01

    Maricopa county is the area of Arizona receiving top priority since it contains over half of the state's population. The county is located entirely within the Basin and Range physiographic region in which geothermal resources are known to occur. Several approaches were taken to match potential users to geothermal resources. One approach involved matching some of the largest facilities in the county to nearby geothermal resources. Other approaches involved identifying industrial processes whose heat requirements are less than the average assessed geothermal reservoir temperature of 110/sup 0/C (230/sup 0/F). Since many of the industries are located on or near geothermal resources, geothermal energy potentially could be adapted to many industrial processes.

  17. Regulatory facility guide for Ohio

    SciTech Connect

    Anderson, S.S.; Bock, R.E.; Francis, M.W.; Gove, R.M.; Johnson, P.E.; Kovac, F.M.; Mynatt, J.O.; Rymer, A.C.

    1994-02-28

    The Regulatory Facility Guide (RFG) has been developed for the DOE and contractor facilities located in the state of Ohio. It provides detailed compilations of international, federal, and state transportation-related regulations applicable to shipments originating at destined to Ohio facilities. This RFG was developed as an additional resource tool for use both by traffic managers who must ensure that transportation operations are in full compliance with all applicable regulatory requirements and by oversight personnel who must verify compliance activities.

  18. Archuleta County CO Lineaments

    DOE Data Explorer

    Zehner, Richard E.

    2012-01-01

    Citation Information: Originator: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Originator: Geothermal Development Associates, Reno, Nevada Publication Date: 2012 Title: Archuleta Lineaments Edition: First Publication Information: Publication Place: Reno Nevada Publisher: Geothermal Development Associates, Reno, Nevada Description: This layer traces apparent topographic and air-photo lineaments in the area around Pagosa springs in Archuleta County, Colorado. It was made in order to identify possible fault and fracture systems that might be conduits for geothermal fluids. Geothermal fluids commonly utilize fault and fractures in competent rocks as conduits for fluid flow. Geothermal exploration involves finding areas of high near-surface temperature gradients, along with a suitable “plumbing system” that can provide the necessary permeability. Geothermal power plants can sometimes be built where temperature and flow rates are high. To do this, georeferenced topographic maps and aerial photographs were utilized in an existing GIS, using ESRI ArcMap 10.0 software. The USA_Topo_Maps and World_Imagery map layers were chosen from the GIS Server at server.arcgisonline.com, using a UTM Zone 13 NAD27 projection. This line shapefile was then constructed over that which appeared to be through-going structural lineaments in both the aerial photographs and topographic layers, taking care to avoid manmade features such as roads, fence lines, and right-of-ways. These lineaments may be displaced somewhat from their actual location, due to such factors as shadow effects with low sun angles in the aerial photographs. Note: This shape file was constructed as an aid to geothermal exploration in preparation for a site visit for field checking. We make no claims as to the existence of the lineaments, their location, orientation, and nature. Spatial Domain: Extent: Top: 4132831.990103 m Left: 311979.997741 m Right: 331678.289280 m Bottom: 4116067

  19. Beneficial application of landfill mining Millersville Landfill, Anne Arundel County, MD

    SciTech Connect

    Vanetti, D.J.

    1995-09-01

    Several studies and investigations have been completed for the Millersville Sanitary Landfill in Anne Arundel County, Maryland. The studies and reports range from detailed hydrogeologic investigations through review of closure alternatives for the individual refuse disposal cells located at the landfill. As a result of the evaluations and studies, one recommendation that was put before Anne Arundel County is the excavation and relocation of refuse from Cell 3 to: (1) create an infiltration basin; and (2) reduce the overall refuse footprint at the site, resulting in reduce long term environmental impacts and closure costs. Subsequent to this recommendation, several preliminary reviews have been held between Anne Arundel County, regulatory agencies and their consultants, Stearns & Wheler. These discussions indicated that it would be feasible, and the concept acceptable, to relocate the refuse in Cell 3 to ultimately create an infiltration basin. Subsequent to the preliminary meetings, a project plan and construction Contract Documents and Drawings were developed by Stearns & Wheler. The Project Plan was submitted to the State regulatory agencies (Maryland and Department of Environment (MDE) and Maryland Department of Natural Resources (DNR)), Millersville Landfill Citizen`s Advisory Committee, and Anne Arundel County (Department of public Works (DPW), Permit Acquisition and Code Enforcement (PACE) and Soil Conservation District (SCD)) for review and comment prior to undertaking the relocation of refuse in Cell 3.

  20. The limits of regulatory toxicology

    SciTech Connect

    Carrington, Clark D.; Bolger, P. Michael

    2010-03-01

    The Acceptable Daily Intake (ADI) has been used by regulatory and public health organizations (e.g., the U.S. Food and Drug and Administration, and the World Health Organization) for chemicals for more than 50 years. The ADI concept was also initially employed at the U.S. Environmental Protection Agency at its inception in 1971, although with the adoption of newer terminology, it later became known as the Reference Dose (RfD). It is clear from the literature that both were first devised as instruments of regulatory policy. In the intervening years, it has become common to use language that implies that these standards are statements of scientific fact. Similarly, some of the discretionary or default values that are used to derive regulatory standards are represented as scientific assumptions when in fact they also represent regulatory policy. This confusion impedes both the best use of the available science and informed public participation in policy making. In addition, the misconception of the ADI or the RfD as statements of scientific fact may impede the consideration of alternative means to reduce exposure to chemicals that may be harmful, including regulatory measures that do not involve prescribing a regulatory concentration limit.

  1. Community Analysis for the Pitkin County Library.

    ERIC Educational Resources Information Center

    Kirwin, Florence M.

    This document analyzes the social and demographic characteristics of Pitkin County, Colorado (population 12,000) and the Pitkin County Library located in Aspen (24,000 volumes). The report contains statistics gathered from the 1978 Mid-Term U.S. Bureau Census of Pitkin County, as well as other statistics from local, state, and federal sources; the…

  2. Community Types and Mortality in Georgia Counties

    ERIC Educational Resources Information Center

    Young, Frank W.

    2012-01-01

    Using an "ecological regional analysis" methodology for defining types of communities and their associated mortality rates, this study of Georgia's 159 counties finds that the suburban and town centered counties have low mortality while the city-centered type predicts low mortality for the whites. The military-centered counties do not predict. The…

  3. The surficial aquifer in Pinellas County, Florida

    USGS Publications Warehouse

    Causseaux, K.W.

    1985-01-01

    The surficial aquifer in Pinellas County, Florida, contains potable water throughout most of the county and is a potential source of water to augment the public supply that is presently imported from adjacent counties. The county accounts for 38 percent of the public supply consumption of ground water in the 11-county area of west-central Florida and 68 percent of this water is imported from two adjacent counties. The surficial aquifer has a saturated thickness of more than 30 feet throughout most of the county. Specific capacity per foot of screen for wells is less than 0.1 gallon per minute per foot of drawdown in some parts of the county, but yield is sufficient in most of the county for many small uses with shallow-well pumps. Minimum potential yield varies from 5 gallons per minute in the northern part of the county to more than 30 gallons per minute in the south. Concentrations of iron are high enough in parts of the county to cause staining. Chloride concentrations are less than 100 milligrams per liter in most of the county and do not pose a problem for many uses. (USGS)

  4. Trouble Brewing in Orange County. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    Orange County will soon face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that Orange County faces a total $41.2 billion liability for retiree benefits that are underfunded--including $9.4 billion for the county pension system and an estimated…

  5. Fresno County Mock Trial Competition.

    ERIC Educational Resources Information Center

    Fresno City Unified School District, CA.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: The Fresno County Office of Education and the Fresno Unified School District hosted the Mock Trial Competition. The state competition is sponsored by the Constitutional Rights Foundation, with cosponsorship from the California State Bar Association and the California Young Lawyer's Association. This…

  6. Composting in Prince William County

    SciTech Connect

    Lyons, K.

    1995-10-01

    Hidden in a small industrial corner of Prince Williams County, in Northern Virginia, a composting facility, after its first flourishing year in business, has found itself part of a symbiotic triangle. Along with a landfill and a waste-to-energy (WTE) plant, the composting facility is one of three programs that make up a joint public-private venture and form a interjurisdictional solid waste/refuse exchange agreement. Faced with the prospects of having to close a landfill at the end of the year, a mandate on yard waste collection that was increasing collection tonnage, and no room for further landfill development, Fairfax County, with approximately 900,000 residents, needed help. In a turn-around situation, Prince William County--with approximately 240,000 residents, a low budget, and much space available for development--responded. Together the counties created a solid waste exchange. The basis for the program is a unity between the local governments on some solid waste issues and a composting facility. Composting, specifically yard waste composting, has been among the fastest-growing aspects of waste management. In 1990, the nation was composting 2% of its solid waste. By the end of 1995, according to the US EPA, between 4% and 7% of solid waste will be recovered through composting. The number of yard waste composting facilities operating has increased from 651 in 1988 to more than 3,000 in 1994.

  7. Somerset County Employer Needs Assessment.

    ERIC Educational Resources Information Center

    Rephann, Terance J.

    Allegany Community College in Cumberland, Maryland, conducted an employer assessment survey of Somerset County businesses during the winter of 1995 in order to provide evaluation data for planning and curriculum development for the secondary and postsecondary educational institutions. The survey was mailed to 760 establishments, with a 29 percent…

  8. Kinship Care in Walton County.

    ERIC Educational Resources Information Center

    Charon, Sara L.; Nackerud, Larry

    1996-01-01

    The quality of life of maltreated children placed with relatives was examined through interviews with nine families in Walton County (Georgia) who had taken in related children. Over half of the children had experienced some improvement in home life, school performance, and their physical and mental status. Kinship care families indicated needs…

  9. Southern Nevada Library Services; Serving Lincoln County, Nye County, Esmeralda County through the Clark County Library District: An Evaluation.

    ERIC Educational Resources Information Center

    Dalton, Phyllis I.

    An anecdotal review covers the first year of increased library service in Nye, Lincoln, and Esmeralda Counties, Nevada, under the Southern Nevada Library Services project funded by the Library Services and Construction Act. Using information from questionnaires and site visits, the extent of library services in each community in the area is…

  10. Truancy in Yolo County, California.

    ERIC Educational Resources Information Center

    Sommer, Barbara; Tyburczy, Jason

    The problem of truancy in the elementary and junior high schools of California's Yolo County was investigated during the 1980-81 academic year by means of questionnaires completed by 16 school principals and interviews with 30 people representing schools, school district offices, law enforcement agencies, the Department of Social Services, and the…

  11. Geothermal development plan: Pima County

    NASA Astrophysics Data System (ADS)

    White, D. H.; Goldstone, L. A.

    1982-08-01

    The Pima County Area Development evaluated the county-wide market potential for utilizing geothermal energy. Four potential geothermal resource areas with temperatures less than 1000 C (2120 F) were identified. In addition, one area is identified as having a temperature of 1470 F (2970 F). Geothermal resources are found to occur in Tecson where average population growth rates of two to three percent per year are expected over the next 40 years. Rapid growth in the manufacturing sector and the existence of major copper mines provide opportunities for the direct utilization of geothermal energy. However, available water supplies are identified as a major constraing to projected growth. A regional energy analysis, future predictions for energy consumption, and energy prices are given. Potential geothermal users in Pima County are identified and projections of maximum economic geothermal utilization are given. One hundred fifteen firms in 32 industrial classes have some potential for geothermal use are identified. In addition, 26 agribusiness firms were found in the county.

  12. Hydrogeology of Wood County, Wisconsin

    USGS Publications Warehouse

    Batten, W.G.

    1989-01-01

    The average rate of ground·water pumpage in Wood County in 1985 was 9.7 million gallons per day. Of this rate, about 6 million gallons per day is pumped from municipal-supply wells in seven communities.An additional 1.08 million gallons per day is pumped for agricultural irrigation.

  13. Measles in rural Ohio county.

    PubMed

    Orenstein, W A; Irvin, J; Jennings, M R; Giandelia, J; Halpin, T J; Marks, J S; Conrad, J L

    1980-06-01

    Between December 23, 1975, and March 31, 1976, 169 cases of measles were reported from Defiance County, Ohio, a small rural county in the northwest corner of the State. The outbreak spread from a single junior high school basketball player to eventually involve 19 of the 28 county schools. Among the affected schools, measles attack rates varied from 0.3-7.2% with a mean of 2.0%. A likely source of illness was determined for 160 of the 169 cases (95%). Intraschool transmission was most common, accounting for 97 of the 169 cases (57%) followed by sibling contact for 23 cases (14%). The pattern of measles spread was complex and would have been difficult to predict in advance even if surveillance systems reported each case the day it occurred. A control program held between February 2 and February 20, 1976, vaccinated 5145 of the 11,114 (46.3%) county schoolchildren. Forty-four cases of measles occurred 4 or more days following school clinics, 22 (50%) in children who requested measles vaccine at school clinics, 17 of whom were actually vaccinated. Most of the other cases occurred in students whose parents thought their children to be protected. Measles is a disease which spreads rapidly in a complex pattern over wide geographic areas. A control program vaccinating a large proportion of the children without definitive history of adequate vaccination or disease was apprently effective in curtailing the outbreak.

  14. 75 FR 79929 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Commission ###Semiannual Regulatory Agenda### ] FEDERAL TRADE COMMISSION (FTC) FEDERAL TRADE COMMISSION 16 CFR Ch. I Semiannual Regulatory Agenda AGENCY: Federal Trade Commission. ACTION: Semiannual regulatory... 22(d)(1) of the Federal Trade Commission Act, 15 U.S.C. 57b-3(d)(1), and the Regulatory......

  15. Department of Energy Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Semiannual Regulatory Agenda 10 CFR Chs. II, III, and X 48 CFR Ch. 9 Regulatory Agenda AGENCY: Department of... ``Regulatory Planning and Review,'' 58 FR 51735, and the Regulatory Flexibility Act, 5 U.S.C. 601 et seq... use throughout the rulemaking process. Timetable: Action Date FR Cite Notice: Public Meeting...

  16. Hydrogeology of Webb County, Texas

    USGS Publications Warehouse

    Lambert, Rebecca B.

    2004-01-01

    Introduction: Webb County, in semiarid South Texas on the U.S.-Mexico border, is a region confronted by increasing stresses on natural resources. Laredo (fig. 1), the largest city in Webb County (population 193,000 in 2000), was one of the 10 fastest-growing metropolitan areas in the country during 1990-2000 (Perry and Mackun, 2001). Commercial and industrial activities have expanded throughout the region to support the maquiladora industry (manufacturing plants in Mexico) along the border and other growth as a result of the passage of the North American Free Trade Agreement. The Rio Grande currently (2002) is the primary source of public water supply for Laredo and other cities along the border in Webb County (fig. 1). Other cities, such as Bruni and Mirando City in the southeastern part of the county, rely on ground-water supplies to meet municipal demands. Increased water demand associated with development and population growth in the region has increased the need for the City of Laredo and Webb County to evaluate alternative water sources to meet future demand. Possible options include (1) supplementing the surface-water supply with ground water, and (2) applying artificial storage and recovery (ASR) technology to recharge local aquifers. These options raise issues regarding the hydraulic capability of the aquifers to store economically substantial quantities of water, current or potential uses of the resource, and possible effects on the quality of water resulting from mixing ground water with alternative source waters. To address some of these issues, the U.S. Geological Survey (USGS), in cooperation with the City of Laredo, began a study in 1996 to assess the ground-water resources of Webb County. A hydrogeologic study was conducted to review and analyze available information on the hydrogeologic units (aquifers and confining units) in Webb County, to locate available wells in the region with water-level and water-quality information from the aquifers, and

  17. Regulatory physiology discipline science plan

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The focus of the Regulatory Physiology discipline of the Space Physiology and Countermeasures Program is twofold. First, to determine and study how microgravity and associated factors of space flight affect the regulatory mechanisms by which humans adapt and achieve homeostasis and thereby regulate their ability to respond to internal and external signals; and, second, to study selected physiological systems that have been demonstrated to be influenced by gravity. The Regulatory Physiology discipline, as defined here, is composed of seven subdisciplines: (1) Circadian Rhythms, (2) Endocrinology, (3) Fluid and Electrolyte Regulation, (4) Hematology, (5) Immunology, (6) Metabolism and Nutrition, and (7) Temperature Regulation. The purpose of this Discipline Science Plan is to provide a conceptual strategy for NASA's Life Sciences Division research and development activities in the area of regulatory physiology. It covers the research areas critical to NASA's programmatic requirements for the Extended-Duration Orbiter, Space Station Freedom, and exploration mission science activities. These science activities include ground-based and flight; basic, applied, and operational; and animal and human research and development. This document summarizes the current status of the program, outlines available knowledge, establishes goals and objectives, identifies science priorities, and defines critical questions in regulatory physiology. It contains a general plan that will be used by both NASA Headquarters Program Offices and the field centers to review and plan basic, applied, and operational intramural and extramural research and development activities in this area.

  18. Chester County ground-water atlas, Chester County, Pennsylvania

    USGS Publications Warehouse

    Ludlow, Russell A.; Loper, Connie A.

    2004-01-01

    Chester County encompasses 760 square miles in southeastern Pennsylvania. Groundwater- quality studies have been conducted in the county over several decades to address specific hydrologic issues. This report compiles and describes water-quality data collected during studies conducted mostly after 1990 and summarizes the data in a county-wide perspective. In this report, water-quality constituents are described in regard to what they are, why the constituents are important, and where constituent concentrations vary relative to geology or land use. Water-quality constituents are grouped into logical units to aid presentation: water-quality constituents measured in the field (pH, alkalinity, specific conductance, and dissolved oxygen), common ions, metals, radionuclides, bacteria, nutrients, pesticides, and volatile organic compounds.Waterquality constituents measured in the field, common ions (except chloride), metals, and radionuclides are discussed relative to geology. Bacteria, nutrients, pesticides, and volatile organic compounds are discussed relative to land use. If the U.S. Environmental Protection Agency (USEPA) or Chester County Health Department has drinkingwater standards for a constituent, the standards are included. Tables and maps are included to assist Chester County residents in understanding the water-quality constituents and their distribution in the county. Ground water in Chester County generally is of good quality and is mostly acidic except in the carbonate rocks and serpentinite, where it is neutral to strongly basic. Calcium carbonate and magnesium carbonate are major constituents of these rocks. Both compounds have high solubility, and, as such, both are major contributors to elevated pH, alkalinity, specific conductance, and the common ions. Elevated pH and alkalinity in carbonate rocks and serpentinite can indicate a potential for scaling in water heaters and household plumbing. Low pH and low alkalinity in the schist, quartzite, and

  19. Finding regulatory elements and regulatory motifs: a general probabilistic framework

    PubMed Central

    van Nimwegen, Erik

    2007-01-01

    Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model binding specificities of regulatory factors with position specific weight matrices (WMs), naturally arise within a general Bayesian probabilistic framework. We discuss how WMs are constructed from sets of regulatory sites, how sites for a given WM can be discovered by scanning of large sequences, how to cluster WMs, and more generally how to cluster large sets of sites from different WMs into clusters. We discuss how 'regulatory modules', clusters of sites for subsets of WMs, can be found in large intergenic sequences, and we discuss different methods for ab initio motif finding, including expectation maximization (EM) algorithms, and motif sampling algorithms. Finally, we extensively discuss how module finding methods and ab initio motif finding methods can be extended to take phylogenetic relations between the input sequences into account, i.e. we show how motif finding and phylogenetic footprinting can be integrated in a rigorous probabilistic framework. The article is intended for readers with a solid background in applied mathematics, and preferably with some knowledge of general Bayesian probabilistic methods. The main purpose of the article is to elucidate that all these methods are not a disconnected set of individual algorithmic recipes, but that they are just different facets of a single integrated probabilistic theory. PMID:17903285

  20. The rise of regulatory RNA

    PubMed Central

    Morris, K.V.; Mattick, J.S.

    2015-01-01

    Discoveries over the last decade portend a paradigm shift in molecular biology. Evidence suggests that RNA is not only functional as a messenger between DNA and protein but also in the regulation of genome organization and gene expression, which is increasingly elaborated in complex organisms. Regulatory RNAs appear to operate at many levels, but in particular to play an important role in the epigenetic processes that control differentiation and development. These discoveries suggest a central role for RNA in human evolution and ontogeny. Here we survey the emergence of the previously unsuspected world of regulatory RNAs from an historical perspective. PMID:24776770

  1. Below Regulatory Concern Owners Group:

    SciTech Connect

    Smith, C.F.; Phillips, L.B.; Williams, W.J.

    1988-03-01

    The US Nuclear Regulatory Commission has indicated that Below Regulatory Concern (BRC) exemption of waste streams from the disposal requirements for low level radioactive waste should be based on actual expected nuclide concentration and variability. Because of variations in the importance and relative abundance of nuclides in waste, one or a small number of nuclides may control the detemination of a waste steam as BRC. This study wasconducted to evaluate the relative importance of the major radionucldies in dose assessments for the disposal options and geographic regions under consideration for BRC waste. 6 refs., 25 tabs.

  2. Glycoconjugate Vaccines: The Regulatory Framework.

    PubMed

    Jones, Christopher

    2015-01-01

    Most vaccines, including the currently available glycoconjugate vaccines, are administered to healthy infants, to prevent future disease. The safety of a prospective vaccine is a key prerequisite for approval. Undesired side effects would not only have the potential to damage the individual infant but also lead to a loss of confidence in the respective vaccine-or vaccines in general-on a population level. Thus, regulatory requirements, particularly with regard to safety, are extremely rigorous. This chapter highlights regulatory aspects on carbohydrate-based vaccines with an emphasis on analytical approaches to ensure the consistent quality of successive manufacturing lots.

  3. 75 FR 79799 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Hinchman, Senior Counsel, Office of Legal Policy, Department of Justice, Room 4252, 950 Pennsylvania Avenue... Department of Justice and the Access Board have each gathered a great deal of information regarding the... Justice ###Semiannual Regulatory Agenda### ] DEPARTMENT OF JUSTICE (DOJ) DEPARTMENT OF JUSTICE 8 CFR Ch....

  4. 78 FR 44279 - Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... agenda pursuant to Executive Order 12866, ``Regulatory Planning and Review,'' 58 FR 51735, and the... destruction of controlled substances consistent with the Controlled Substances Act. Timetable: Action Date FR Cite ANPRM 01/21/09 74 FR 3480 ANPRM Comment Period End 03/23/09 Notice of Public Meeting 12/22/10...

  5. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  6. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  7. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  8. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  9. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  10. 78 FR 10249 - Environmental Impact Statement: Will and Kankakee Counties, IL and Lake County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Will and Kankakee Counties, IL and Lake County, IN AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Intent. SUMMARY... Federal Domestic Assistance Program Number 20.205, Highway Research, Planning and Construction....

  11. Physiologically based pharmacokinetic modeling: from regulatory science to regulatory policy.

    PubMed

    Sinha, V; Zhao, P; Huang, S M; Zineh, I

    2014-05-01

    Assessment of controllable sources of intra- and interpatient variability in drug response is of critical importance in the regulatory evaluation of new drugs.(1) Although determinants of response variability would ideally be understood and accounted for before approval of a new pharmaceutical product, this is rarely the case for all; clinical trials in specific populations that definitively test optimal dosing in patient management strategies are not routinely performed prior to drug approval.

  12. Regulatory applications of sediment criteria. Final report

    SciTech Connect

    Not Available

    1987-06-23

    The report briefly describes the development of sediment criteria, discusses their utility and appropriate regulatory applications, and recommends steps to enhance the acceptance of sediment criteria by the regulatory and regulated communities.

  13. Plant Evolution: Evolving Antagonistic Gene Regulatory Networks.

    PubMed

    Cooper, Endymion D

    2016-06-20

    Developing a structurally complex phenotype requires a complex regulatory network. A new study shows how gene duplication provides a potential source of antagonistic interactions, an important component of gene regulatory networks. PMID:27326708

  14. Small Business Administration Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... businesses. Timetable: Action Date FR Cite NPRM 08/00/10 Regulatory Flexibility Analysis Required: Yes Agency... Manufacturing Assistance Act of 2004 (Reauthorization Act) to regulate Small Business Lending Companies (SBLCs... Part XVI Small Business Administration Semiannual Regulatory Agenda ] SMALL...

  15. 75 FR 61531 - Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... E. Norris, Component Integrity Branch, Division of Engineering, Office of Nuclear Regulatory... acceptable alternatives to requirements in the American Society of Mechanical Engineers (ASME) Boiler and.... Harriet Karagiannis, Acting Chief, Regulatory Guide Development Branch, Division of Engineering, Office...

  16. Plant Evolution: Evolving Antagonistic Gene Regulatory Networks.

    PubMed

    Cooper, Endymion D

    2016-06-20

    Developing a structurally complex phenotype requires a complex regulatory network. A new study shows how gene duplication provides a potential source of antagonistic interactions, an important component of gene regulatory networks.

  17. Water resources of Lehigh County, Pennsylvania

    USGS Publications Warehouse

    Wood, Charles R.; Flippo, Herbert N.; Lescinsky, Joseph B.; Barker, James L.

    1972-01-01

    Lehigh County occupies an area of 347 square miles in southeastern Pennsylvania. The northern part of Lehigh County is underlain by the Martinsburg Formation, which consists chiefly of shale and slate. The central part of the county, where most of the population centers are located and much of the urbanization is occurring, is underlain by alternating beds of limestone and dolomite. From oldest to youngest, these carbonate rocks are the Leithsville Formation, the Allentown Formation, the Beekmantown Group, and the Jacksonburg Formation. The southern part of the county is underlain chiefly by the shales, sandstones, and conglomerates of the Brunswick Formation and by metamorphic and igneous rocks.

  18. Waste source reduction county government case study

    SciTech Connect

    1990-12-31

    Itasca County is located in north-central Minnesota, has a population of 42,000 and is known for its forests and scenic waterways. With Beltrami County, it contains the upper watershed of the Mississippi River. Its major industries are timber and tourism. Itasca County government made a commitment to source reduce its waste as much as possible. Secondarily, what they could not reduce they committed themselves to recycle. The project demonstrates functional reduction in practice. It shows that reduction is a realistic goal for county governments and that reduction can be measured on a waste stream by waste stream basis.

  19. Digital computer processing of LANDSAT data for North Alabama. [Linestone County, Madison County, Jackson County, Marshall County, and DeKalb County

    NASA Technical Reports Server (NTRS)

    Bond, A. D.; Atkinson, R. J.; Lybanon, M.; Ramapriyan, H. K.

    1977-01-01

    Computer processing procedures and programs applied to Multispectral Scanner data from LANDSAT are described. The output product produced is a level 1 land use map in conformance with a Universal Transverse Mercator projection. The region studied was a five-county area in north Alabama.

  20. 75 FR 26709 - Clarke County Water Supply Project, Clarke County, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... Natural Resources Conservation Service Clarke County Water Supply Project, Clarke County, IA AGENCY... Water Supply Project, Clarke County, Iowa. ] FOR FURTHER INFORMATION CONTACT: Richard Sims, State... comments by NRCS information related to water supply demand requirements for permitting by the State...

  1. 78 FR 29202 - Environmental Impact Statement: Grand Forks County, North Dakota and Polk County, Minnesota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... Federal Highway Administration Environmental Impact Statement: Grand Forks County, North Dakota and Polk... prepared for a proposed highway project in Grand Forks County, North Dakota and Polk County, Minnesota. FOR... Sorlie Bridge over the Red River between Grand Forks, North Dakota and East Grand Forks,...

  2. 75 FR 42815 - Fulton County, LLC-Abandonment Exemption-in Fulton County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... Surface Transportation Board Fulton County, LLC--Abandonment Exemption--in Fulton County, IN Fulton County, LLC (FC), filed a verified notice of exemption under 49 CFR 1152 subpart F--Exempt Abandonments to... exemption, any employee adversely affected by the abandonment shall be protected under Oregon Short...

  3. The Economic Impact of Schenectady County Community College on Schenectady County, 1981-82.

    ERIC Educational Resources Information Center

    Chestnut, Erma Ruth

    This report on the economic impact of Schenectady County Community College (SCCC) uses a modification of the Caffrey and Isaacs model to assess SCCC-related local business volume, SCCC costs and benefits to the Schenectady County government, and the likely impact on the county if SCCC did not exist. Part I provides background to the study,…

  4. 75 FR 45557 - Prevailing Rate Systems; Definition of Tulsa County, OK, and Angelina County, TX, to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... Counties, TX. Santa Clara, CA On March 9, 2009, we published a final rule (74 FR 9951) that abolished the... County, OK, and Angelina County, TX, to Nonappropriated Fund Federal Wage System Wage Areas AGENCY... area of application to the Oklahoma, OK, nonappropriated fund (NAF) Federal Wage System (FWS) wage...

  5. 75 FR 25308 - Environmental Impact Statement: Winnebago County, IL and Rock County, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Winnebago County, IL and Rock County, WI... Beloit, Rock County, Wisconsin to the interchange of Rockton Road and I-90 southeast of South...

  6. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  7. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  8. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  9. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  10. Nuclear Regulatory Commission 1989 Information Digest

    SciTech Connect

    None,

    1989-03-01

    The Nuclear Regulatory Commission 1989 Information Digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the Commission. This is the first of an annual publication for the general use of the NRC staff and is available to the public. The Digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  11. Genetic flexibility of regulatory networks.

    PubMed

    Hunziker, Alexander; Tuboly, Csaba; Horváth, Péter; Krishna, Sandeep; Semsey, Szabolcs

    2010-07-20

    Gene regulatory networks are based on simple building blocks such as promoters, transcription factors (TFs) and their binding sites on DNA. But how diverse are the functions that can be obtained by different arrangements of promoters and TF binding sites? In this work we constructed synthetic regulatory regions using promoter elements and binding sites of two noninteracting TFs, each sensing a single environmental input signal. We show that simply by combining these three kinds of elements, we can obtain 11 of the 16 Boolean logic gates that integrate two environmental signals in vivo. Further, we demonstrate how combination of logic gates can result in new logic functions. Our results suggest that simple elements of transcription regulation form a highly flexible toolbox that can generate diverse functions under natural selection.

  12. Regulatory cells and transplantation tolerance.

    PubMed

    Cobbold, Stephen P; Waldmann, Herman

    2013-06-01

    Transplantation tolerance is a continuing therapeutic goal, and it is now clear that a subpopulation of T cells with regulatory activity (Treg) that express the transcription factor foxp3 are crucial to this aspiration. Although reprogramming of the immune system to donor-specific transplantation tolerance can be readily achieved in adult mouse models, it has yet to be successfully translated in human clinical practice. This requires that we understand the fundamental mechanisms by which donor antigen-specific Treg are induced and function to maintain tolerance, so that we can target therapies to enhance rather than impede these regulatory processes. Our current understanding is that Treg act via numerous molecular mechanisms, and critical underlying components such as mTOR inhibition, are only now emerging. PMID:23732858

  13. 21 CFR 500.88 - Regulatory method.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Regulatory method. 500.88 Section 500.88 Food and... § 500.88 Regulatory method. (a) The sponsor shall submit for evaluation and validation a regulatory method developed to monitor compliance with FDA's operational definition of no residue. (b)...

  14. 78 FR 44399 - Semiannual Regulatory Flexibility Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Capital, Implementation of Basel III, Minimum Regulatory Capital Ratios, Capital Adequacy, and Transition... leverage capital requirements. Timetable: Action Date FR Cite Board Requested Comment 08/30/12 77 FR 53059... Capital Rules: Regulatory Capital, Implementation of Basel III, Minimum Regulatory Capital Ratios,......

  15. Department of Energy Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... OF ENERGY Semiannual Regulatory Agenda 10 CFR Chs. II, III, and X 48 CFR Ch. 9 Regulatory Agenda... Review,'' 58 FR 51735, and the Regulatory Flexibility Act, 5 U.S.C. 601 et seq. SUPPLEMENTARY INFORMATION... and direct heating equipment. This is the second review for water heaters. Timetable: Action Date...

  16. 78 FR 1624 - Fall 2012 Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... and not to existing residential wood-heating appliances. Timetable: Action Date FR Cite NPRM 06/00/13... that start up after the regulatory agenda is signed? H. What tools are available for mining regulatory..., ``Regulatory Planning and Review'' (58 FR 51735, Oct. 4, 1993), as supplemented by Executive Order (EO)...

  17. 78 FR 1594 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    .... Timetable: Action Date FR Cite ANPRM 01/00/13 Regulatory Flexibility Analysis Required: Yes. Agency Contact...: Action Date FR Cite Final Action 12/00/12 Regulatory Flexibility Analysis Required: Yes. Agency Contact... idle facilities. Completed: Reason Date FR Cite Withdrawn 10/18/12 Regulatory Flexibility...

  18. 78 FR 23507 - Notice of Regulatory Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... regulations may be made more effective and less burdensome. \\1\\ Regulatory Review Plan, 77 FR 10351 (Feb. 22...'s Director. \\2\\ Notice of Regulatory Review Plan, 76 FR 59066 (Sept. 23, 2011). \\3\\ Regulatory Review Plan, 77 FR 10351 (Feb. 22, 2012). This Notice initiates the first such review. II. Request...

  19. 21 CFR 500.88 - Regulatory method.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Regulatory method. 500.88 Section 500.88 Food and... § 500.88 Regulatory method. (a) The sponsor shall submit for evaluation and validation a regulatory method developed to monitor compliance with FDA's operational definition of no residue. (b)...

  20. Securities and Exchange Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    .... Timetable: Action Date FR Cite NPRM 03/00/11 Regulatory Flexibility Analysis Required: Yes Agency Contact...: Action Date FR Cite NPRM 12/00/10 Regulatory Flexibility Analysis Required: Yes Agency Contact: Jennifer... Date FR Cite NPRM 09/00/10 Regulatory Flexibility Analysis Required: Yes Agency Contact: Anthony...

  1. Summation from a regulatory perspective

    SciTech Connect

    Ohanian, E.V.; Cotruvo, J.A.

    1986-11-01

    There is an urgent need to discuss the Office of Drinking Water's standard-setting or rule making process since most of the researchers whose papers are presented here directly or indirectly play a crucial role in this complex undertaking. Therefore, this paper will address the research data required to support policy making and regulatory decisions pertaining to health effects of disinfectants and disinfection by-products.

  2. Regulatory motifs in Chk1

    PubMed Central

    Caparelli, Michael L.; O’Connell, Matthew J.

    2013-01-01

    Chk1 is the effector kinase of the G2 DNA damage checkpoint. Chk1 homologs possess a highly conserved N-terminal kinase domain and a less conserved C-terminal regulatory domain. In response to DNA damage, Chk1 is recruited to mediator proteins assembled at lesions on replication protein A (RPA)-coated single-stranded DNA (ssDNA). Chk1 is then activated by phosphorylation on S345 in the C-terminal regulatory domain by the PI3 kinase-related kinases ATM and ATR to enforce a G2 cell cycle arrest to allow time for DNA repair. Models have emerged in which this C-terminal phosphorylation relieves auto-inhibitory regulation of the kinase domain by the regulatory domain. However, experiments in fission yeast have shown that deletion of this putative auto-inhibitory domain actually inactivates Chk1 function. We show here that Chk1 homologs possess a kinase-associated 1 (KA1) domain that possesses residues previously implicated in Chk1 auto-inhibition. In addition, all Chk1 homologs have a small and highly conserved C-terminal extension (CTE domain). In fission yeast, both of these motifs are essential for Chk1 activation through interaction with the mediator protein Crb2, the homolog of human 53BP1. Thus, through different intra- and intermolecular interactions, these motifs explain why the regulatory domain exerts both positive and negative control over Chk1 activation. Such motifs may provide alternative targets to the ATP-binding pocket on which to dock Chk1 inhibitors as anticancer therapeutics. PMID:23422000

  3. Regulatory aspects of neutron radiography

    NASA Astrophysics Data System (ADS)

    Hammer, J.

    1999-11-01

    While full legislation for industrial radiography with gamma and X-rays already exists in many countries, the situation is different for neutron radiography. Therefore, the licensing for equipment and procedures in this field has to be based on basic principles of national and international rules. This contribution will explain how the regulatory body in Switzerland deals with neutron radiography installations in order to maintain national standards of health and safety.

  4. 75 FR 54419 - Environmental Impact Statement: Yellowstone County, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... Federal Highway Administration Environmental Impact Statement: Yellowstone County, MT AGENCY: Federal... highway project in Yellowstone County, Montana. FOR FURTHER INFORMATION CONTACT: Brian Hasselbach, Right... (I-90) and Old Highway 312 in or near the city of Billings, Yellowstone County, Montana....

  5. EXTERIOR VIEW LOOKING WEST ALONG JEFFERSON COUNTY 71 WITH RAILROAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EXTERIOR VIEW LOOKING WEST ALONG JEFFERSON COUNTY 71 WITH RAILROAD BRIDGE (RIGHT), SADDLEBAG COTTAGE (LEFT) AND COAL TRUCK. - Linn Crossing Trestle Bridge, Spanning County Road 71, Linn Crossing, Jefferson County, AL

  6. 111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND, JUNE 1933. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  7. 113. "EXISTING MAJOR HIGHWAYS". FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    113. "EXISTING MAJOR HIGHWAYS". FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND. JUNE 1933 - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  8. 112. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    112. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND. JUNE 1933. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  9. Implications of Swedish National Regulatory Framework of the Patient Accessible Electronic Health Record.

    PubMed

    Scandurra, Isabella; Lyttkens, Leif; Eklund, Benny

    2016-01-01

    Online access to your own electronic health record is a controversial issue. In a Swedish county such eHealth service has been in operation since 2012 and it is now being widely deployed in the other counties. This first review presents work regarding current National Regulatory Framework (NRF) related to the public eHealth service Patient Accessible Electronic Health Record (PAEHR) and points out how electable paragraphs have been applied in different counties. Potential implications due to the different decisions made are discussed in terms of patient centricity and health information outcome. In current PAEHR, care providers have assessed differently how to apply the NRF. For the patients, this means that information gathered from the health record may be displayed differently, depending on where, when and why they seek treatment. When a patient visits different care providers such solution may cause confusion and its purpose may go lost. Consequently a revised NRF with less electable paragraphs is recommended, as well as adherence to the next NRF by all county councils. PMID:27577474

  10. 77 FR 56686 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's... FINRA and at the Commission's Public Reference Room. II. Self-Regulatory Organization's Statement of...

  11. 78 FR 70602 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule... of the rules in accordance with the requirements of Form 19b-4. II. Self-Regulatory...

  12. Landsliding in Allegheny County, Pennsylvania

    USGS Publications Warehouse

    Briggs, Reginald Peter; Pomeroy, John S.; Davies, William E.

    1975-01-01

    Man should proceed with caution if modifications such as loading, excavation, or changes of the water regime are contemplated for slopes in Allegheny County, especially those slopes described on the map as highly sensitive to disturbance by man. Features indicative of unstable slope conditions include: cracks in buildings, yard walls, and pools; doors and windows that jam; fences and other linear features bowed out of line; tilted trees and utility poles; cracks and steplike ground features; hummocky ground; and water seeps. Geologic factors related to the landsliding process include rock types, layering, fracturing, and attitude; nature of soil cover; permeability of rocks and soils; and steepness of slope.

  13. Geothermal development plan: Pinal county

    SciTech Connect

    White, D.H.

    1981-01-01

    Wells drilled in the county provide evidence of geothermal energy sufficient for process heat and space heating and cooling applications. Annual energy consumption was estimated for industries whose process heat requirements are less than 105/sup 0/C (221/sup 0/F). This information was then used to model the introduction of geothermal energy into the process heat market. Also, agriculture and agribusiness industries were identified. Many of these are located on or near a geothermal resource and might be able to utilize geothermal energy in their operations.

  14. Water resources of Sweetwater County, Wyoming

    USGS Publications Warehouse

    Mason, Jon P.; Miller, Kirk A.

    2004-01-01

    Sweetwater County is located in the southwestern part of Wyoming and is the largest county in the State. A study to quantify the availability and describe the chemical quality of surface-water and ground-water resources in Sweetwater County was conducted by the U.S. Geological Survey in cooperation with the Wyoming State Engineers Office. Most of the county has an arid climate. For this reason a large amount of the flow in perennial streams within the county is derived from outside the county. Likewise, much of the ground-water recharge to aquifers within the county is from flows into the county, and occurs slowly. Surface-water data were not collected as part of the study. Evaluations of streamflow and stream-water quality were limited to analyses of historical data and descriptions of previous investigations. Forty-six new ground-water-quality samples were collected as part of the study and the results from an additional 782 historical ground-water-quality samples were reviewed. Available hydrogeologic characteristics for various aquifers throughout the county also are described. Flow characteristics of streams in Sweetwater County vary substantially depending on regional and local basin characteristics and anthropogenic factors. Because precipitation amounts in the county are small, most streams in the county are ephemeral, flowing only as a result of regional or local rainfall or snowmelt runoff. Flows in perennial streams in the county generally are a result of snowmelt runoff in the mountainous headwater areas to the north, west, and south of the county. Flow characteristics of most perennial streams are altered substantially by diversions and regulation. Water-quality characteristics of selected streams in and near Sweetwater County during water years 1974 through 1983 were variable. Concentrations of dissolved constituents, suspended sediment, and bacteria generally were smallest at sites on the Green River because of resistant geologic units, increased

  15. 76 FR 28415 - Fresno County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Robbin Ekman, Fresno County Resource Advisory Committee Coordinator, c/ o Sierra National Forest, High... FURTHER INFORMATION CONTACT: Robbin Ekman, Fresno County Resource ] Advisory Committee Coordinator,...

  16. 76 FR 44302 - Fresno County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... Robbin Ekman, Fresno County Resource Advisory Committee Coordinator, c/ o Sierra National Forest, High... FURTHER INFORMATION CONTACT: Robbin Ekman, Fresno County Resource Advisory Committee Coordinator,...

  17. Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT

  18. Regulatory pathways for vaccines for developing countries.

    PubMed

    Milstien, Julie; Belgharbi, Lahouari

    2004-02-01

    Vaccines that are designed for use only in developing countries face regulatory hurdles that may restrict their use. There are two primary reasons for this: most regulatory authorities are set up to address regulation of products for use only within their jurisdictions and regulatory authorities in developing countries traditionally have been considered weak. Some options for regulatory pathways for such products have been identified: licensing in the country of manufacture, file review by the European Medicines Evaluation Agency on behalf of WHO, export to a country with a competent national regulatory authority (NRA) that could handle all regulatory functions for the developing country market, shared manufacturing and licensing in a developing country with competent manufacturing and regulatory capacity, and use of a contracted independent entity for global regulatory approval. These options have been evaluated on the basis of five criteria: assurance of all regulatory functions for the life of the product, appropriateness of epidemiological assessment, applicability to products no longer used in the domestic market of the manufacturing country, reduction of regulatory risk for the manufacturer, and existing rules and regulations for implementation. No one option satisfies all criteria. For all options, national infrastructures (including the underlying regulatory legislative framework, particularly to formulate and implement local evidence-based vaccine policy) must be developed. WHO has led work to develop this capacity with some success. The paper outlines additional areas of action required by the international community to assure development and use of vaccines needed for the developing world. PMID:15042235

  19. Regulatory pathways for vaccines for developing countries.

    PubMed Central

    Milstien, Julie; Belgharbi, Lahouari

    2004-01-01

    Vaccines that are designed for use only in developing countries face regulatory hurdles that may restrict their use. There are two primary reasons for this: most regulatory authorities are set up to address regulation of products for use only within their jurisdictions and regulatory authorities in developing countries traditionally have been considered weak. Some options for regulatory pathways for such products have been identified: licensing in the country of manufacture, file review by the European Medicines Evaluation Agency on behalf of WHO, export to a country with a competent national regulatory authority (NRA) that could handle all regulatory functions for the developing country market, shared manufacturing and licensing in a developing country with competent manufacturing and regulatory capacity, and use of a contracted independent entity for global regulatory approval. These options have been evaluated on the basis of five criteria: assurance of all regulatory functions for the life of the product, appropriateness of epidemiological assessment, applicability to products no longer used in the domestic market of the manufacturing country, reduction of regulatory risk for the manufacturer, and existing rules and regulations for implementation. No one option satisfies all criteria. For all options, national infrastructures (including the underlying regulatory legislative framework, particularly to formulate and implement local evidence-based vaccine policy) must be developed. WHO has led work to develop this capacity with some success. The paper outlines additional areas of action required by the international community to assure development and use of vaccines needed for the developing world. PMID:15042235

  20. Educational and Demographic Profile: Mendocino County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Mendocino County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  1. Geothermal development issues: Recommendations to Deschutes County

    SciTech Connect

    Gebhard, C.

    1982-07-01

    This report discusses processes and issues related to geothermal development. It is intended to inform planners and interested individuals in Deschutes County about geothermal energy, and advise County officials as to steps that can be taken in anticipation of resource development. (ACR)

  2. Latinos and Education in Ventura County.

    ERIC Educational Resources Information Center

    Segura, Denise A.

    This paper provides an overview of demographic and educational attainment data on Latinos in Ventura County, California, and describes an ongoing initiative to increase Latino college attendance through improved K-12 preparation and family involvement. In both its urban and rural areas, Ventura County harbors large Latino populations who are…

  3. Educational and Demographic Profile: Lake County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Lake County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  4. Commodity Flow Study - Clark County, Nevada, USA

    SciTech Connect

    Conway, S.Ph.D.; Navis, I.

    2008-07-01

    The United States Department of Energy has designated Clark County, Nevada as an 'Affected Unit of Local Government' due to the potential for impacts by activities associated with the Yucca Mountain High Level Nuclear Waste Repository project. Urban Transit, LLC has led a project team of transportation including experts from the University of Nevada Las Vegas Transportation Research Center to conduct a hazardous materials community flow study along Clark County's rail and truck corridors. In addition, a critical infrastructure analysis has also been carried out in order to assess the potential impacts of transportation within Clark County of high level nuclear waste and spent nuclear fuel to a proposed repository 90 miles away in an adjacent county on the critical infrastructure in Clark County. These studies were designed to obtain information relating to the transportation, identification and routing of hazardous materials through Clark County. Coordinating with the United States Department of Energy, the U.S. Department of Agriculture, the U. S. Federal Highway Administration, the Nevada Department of Transportation, and various other stakeholders, these studies and future research will examine the risk factors along the entire transportation corridor within Clark County and provide a context for understanding the additional vulnerability associated with shipping spent fuel through Clark County. (authors)

  5. Educational and Demographic Profile: San Benito County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Benito County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  6. Public Library Service for San Benito County.

    ERIC Educational Resources Information Center

    McGovern, Gail

    A sparsely populated, agricultural area, San Benito County (California) provides library services in conjunction with the Hollister city library and in cooperation with the San Juan Bautista city library. Financing comes from the county general fund. There are no written goals or policy statements and no professionally trained librarians. As…

  7. Groundwater management and protection Madison County, Alabama

    SciTech Connect

    French, J.H.; Strunk, J.W.

    1990-07-01

    Groundwater is extremely important to Madison County as it provides nearly three quarters of the county's drinking water. In recent years, Madison County has increasingly recognized the need to protect its groundwater resource. A supply of usable groundwater is one element of a high quality environment, which can help spur economic development and provide for the needs of a growing population. Without planning protection and understanding of possible consequences, however, economic development and population pressures can cause a gradual degradation of groundwater. In April 1987, the Tennessee Valley Authority (TVA) convened a local groundwater steering group in Madison County. At the first meeting the ground agreed upon these goals: (1) to seek incorporate groundwater protection into the planning and development process for Madison County, (2) to support efforts by Madison County to obtain authority to adopt zoning ordinances and subdivision regulations, and (3) to develop a groundwater management plan for the county. This report provides essential information needed in developing a plan and is based on the following assumptions: the citizens of Madison County value the environment in which they live and wish to protect it from pollution; continued economic development is necessary for a healthy local economy; and a healthy economy can be sustained and nurtured, without degradation of the groundwater resource, through countywide planning, education, and participation.

  8. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  9. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  10. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  11. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  12. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  13. A Rural County's Response to Homelessness.

    ERIC Educational Resources Information Center

    Loughran, Elizabeth Lee; White, Priscilla

    This paper describes the response of one locality, a rural county in Western Massachusetts, to the reality of rural homelessness. Jessie's House, in Hampshire County, Massachusetts, is a short-term emergency shelter providing meals, housing, and advocacy to homeless families and individuals. The shelter has a staff of three full-time residents and…

  14. Analysis of County School Districts in Arkansas.

    ERIC Educational Resources Information Center

    Budd, Karol B.; Charlton, J.L.

    The 1948, Arkansas School District Reorganization Act was passed in an effort to reduce the 1589 small school districts to a smaller number. Those districts not consolidated would form county districts. As of the 1967-68 school year, 26 of these county districts remained. The purpose of this study was to provide information drawing attention to…

  15. Socioeconomic Heterogeneity of Mining-Dependent Counties.

    ERIC Educational Resources Information Center

    Nord, Mark; Luloff, A. E.

    1993-01-01

    Although the socioeconomic well-being of all U.S. mining-dependent counties was slightly above the national average in 1990, disaggregation reveals substantial effects of region and mining subsector. In particular, southern and Great Lakes coal-mining counties had significantly lower high school graduation rates and higher poverty and unemployment…

  16. A Profile of Anson County, North Carolina.

    ERIC Educational Resources Information Center

    Farr, M. Gaston; And Others

    Since 1950 Anson County, North Carolina, has had major contributions to economic development, a source of great concern to residents of the almost entirely rural area. The increased capacity of the Blewitt Falls Dam power output and the county-wide water filtration system (one of only a few in the United States today) are attractive to industry.…

  17. [A Profile of Kershaw County, South Carolina].

    ERIC Educational Resources Information Center

    Lilley, Stephen C.; McLean, Edward L.

    Careful long-range planning and slow, deliberate growth have benefitted Kershaw County's 500,000 pleasantly varied acres near the state capitol. The county, famous for its equestrian activity, boasts prestige stables, riding clubs, and trails. In addition there are lakes and numerous parks. Leaders want to maintain this aesthetic appeal while…

  18. A Profile of Hardee County, Florida.

    ERIC Educational Resources Information Center

    Beaulieu, Lionel J.; Anderson, Deborah S.

    In 1977 leaders of Hardee County, Florida, listed relationships and attitudes of residents, rural atmosphere, environmental conditions, and economic potential among the county's strong points, and public service and facility improvements, developing economic potential, recreational and entertainment development, and planning and zoning as its most…

  19. Educational and Demographic Profile: Yolo County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Yolo County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  20. The Farm Crisis and Decatur County.

    ERIC Educational Resources Information Center

    Flora, Jan L.; And Others

    This case study assesses the impact of the farm sector on the economy and social organization of Decatur County (Kansas), a county which has historically depended on agriculture for its livelihood. Data were obtained from analysis of time series statistical indicators for the period between 1966 and 1984, questionnaire responses of local…

  1. Educational and Demographic Profile: San Joaquin County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Joaquin County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  2. Geothermal development plan: Yuma County

    NASA Astrophysics Data System (ADS)

    White, D. H.; Goldstone, L. A.

    1982-08-01

    The potential for utilizing geothermal energy was evaluated. Four potential geothermal resource areas with temperatures less than 900C (1940F) were identified, and in addition, two areas are inferred to contain geothermal resources with intermediate temperature potential. The resource areas are isolated. One resource site contains a hot dry rock resource. Anticipated population growth in the county is expected to be 2% per year over the next 40 years. The primary employment sector is agriculture, though some light industry is located in the county. Water supplies are found to be adequate to support future growth without adverse affect on agriculture. In addition, several agricultural processors were found, concentrated in citrus processing and livestock raising. It is suggested that by the year 2000, geothermal energy may economically provide the energy equivalent of 53,000 barrels of oil per year to the industrial sector if developed privately. Geothermal utilization projections increase to 132,000 barrels of oil per year by 2000 if a municipal utility developed the resource.

  3. Family planning in Nangong County.

    PubMed

    Sun, X

    1980-04-01

    Family planning has been practiced in Nangong county, China, since 1971; as a result the population growth rate has dropped from 16.7/1000 to 3.6/1000 in 1979; 98% of women of childbearing age use contraception, and most couples have only 1 child. Before 1971 most couples had 4-5 children; per capita grain rations had to be reduced because of the increase in population, and more grain had to be supplied by the state. 1 child families are now rewarded with an annual monetary bonus, extra grain allocations for the child, free tuition in schools, and preference in job placement and medical treatment. Parents who have more than 2 children are penalized by the withdrawal of 10% of their monthly earnings. The idea of "1 couple 1 child" is a radical change from China's traditional culture, which viewed children especially sons, as an insurance against old age insecurity. Marriage at a later age is also encouraged; in Nangong county none of the men of marriageable age married before 25, and none of the women before 23. As a result of promoting family planning Nangong country has ceased to need grain subsidies from the state, and in recent years has had a 10,000 ton surplus to sell.

  4. Family planning in Nangong County.

    PubMed

    Sun, X

    1980-04-01

    Family planning has been practiced in Nangong county, China, since 1971; as a result the population growth rate has dropped from 16.7/1000 to 3.6/1000 in 1979; 98% of women of childbearing age use contraception, and most couples have only 1 child. Before 1971 most couples had 4-5 children; per capita grain rations had to be reduced because of the increase in population, and more grain had to be supplied by the state. 1 child families are now rewarded with an annual monetary bonus, extra grain allocations for the child, free tuition in schools, and preference in job placement and medical treatment. Parents who have more than 2 children are penalized by the withdrawal of 10% of their monthly earnings. The idea of "1 couple 1 child" is a radical change from China's traditional culture, which viewed children especially sons, as an insurance against old age insecurity. Marriage at a later age is also encouraged; in Nangong county none of the men of marriageable age married before 25, and none of the women before 23. As a result of promoting family planning Nangong country has ceased to need grain subsidies from the state, and in recent years has had a 10,000 ton surplus to sell. PMID:12264032

  5. 75 FR 28073 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory Guide, DG-3039, ``Standard Format and Content...

  6. 75 FR 48382 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory Guide, DG-1228, ``Standard Format and Content...

  7. 78 FR 44165 - Nuclear Regulatory Commission Enforcement Policy

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Nuclear Regulatory Commission Enforcement Policy AGENCY: Nuclear Regulatory Commission. ACTION: Enforcement policy; request for comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is...

  8. 75 FR 16525 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Branch, Division of Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear...

  9. 75 FR 36715 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION.... Sturzebecher, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: (301) 251- 7494 or...

  10. Imperial County geothermal development annual meeting: summary

    SciTech Connect

    Not Available

    1983-01-01

    All phases of current geothermal development in Imperial County are discussed and future plans for development are reviewed. Topics covered include: Heber status update, Heber binary project, direct geothermal use for high-fructose corn sweetener production, update on county planning activities, Brawley and Salton Sea facility status, status of Imperial County projects, status of South Brawley Prospect 1983, Niland geothermal energy program, recent and pending changes in federal procedures/organizations, plant indicators of geothermal fluid on East Mesa, state lands activities in Imperial County, environmental interests in Imperial County, offshore exploration, strategic metals in geothermal fluids rebuilding of East Mesa Power Plant, direct use geothermal potential for Calipatria industrial Park, the Audubon Society case, status report of the Cerro Prieto geothermal field, East Brawley Prospect, and precision gravity survey at Heber and Cerro Prieto geothermal fields. (MHR)

  11. Water resources of Duval County, Florida

    USGS Publications Warehouse

    Phelps, G.G.

    1994-01-01

    The report describes the hydrology and water resources of Duval County, the development of its water supplies, and water use within the county. Also included are descriptions of various natural features of the county (such as topography and geology), an explanation of the hydrologic cycle, and an interpretation of the relationship between them. Ground-water and surface-water resources and principal water-quality features within the county are also discussed. The report is intended to provide the general public with an overview of the water resources Of Duval County, and to increase public awareness of water issues. Information is presented in nontechnical language to enable the general reader to understand facts about water as a part of nature, and the problems associated with its development and use.

  12. Environmental assessment: Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified a location in Deaf Smith County, Texas, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Deaf Smith County site and the eight other potentially sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. The Deaf Smith County site is in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. On the basis of the evaluations reported in this EA, the DOE has found that the Deaf Smith County site is not disqualified under the guidelines. On the basis of these findings, the DOE is nominating the Deaf Smith County site as one of the five sites suitable for characterization. 591 refs., 147 figs., 173 tabs.

  13. A global regulatory science agenda for vaccines.

    PubMed

    Elmgren, Lindsay; Li, Xuguang; Wilson, Carolyn; Ball, Robert; Wang, Junzhi; Cichutek, Klaus; Pfleiderer, Michael; Kato, Atsushi; Cavaleri, Marco; Southern, James; Jivapaisarnpong, Teeranart; Minor, Philip; Griffiths, Elwyn; Sohn, Yeowon; Wood, David

    2013-04-18

    The Decade of Vaccines Collaboration and development of the Global Vaccine Action Plan provides a catalyst and unique opportunity for regulators worldwide to develop and propose a global regulatory science agenda for vaccines. Regulatory oversight is critical to allow access to vaccines that are safe, effective, and of assured quality. Methods used by regulators need to constantly evolve so that scientific and technological advances are applied to address challenges such as new products and technologies, and also to provide an increased understanding of benefits and risks of existing products. Regulatory science builds on high-quality basic research, and encompasses at least two broad categories. First, there is laboratory-based regulatory science. Illustrative examples include development of correlates of immunity; or correlates of safety; or of improved product characterization and potency assays. Included in such science would be tools to standardize assays used for regulatory purposes. Second, there is science to develop regulatory processes. Illustrative examples include adaptive clinical trial designs; or tools to analyze the benefit-risk decision-making process of regulators; or novel pharmacovigilance methodologies. Included in such science would be initiatives to standardize regulatory processes (e.g., definitions of terms for adverse events [AEs] following immunization). The aim of a global regulatory science agenda is to transform current national efforts, mainly by well-resourced regulatory agencies, into a coordinated action plan to support global immunization goals. This article provides examples of how regulatory science has, in the past, contributed to improved access to vaccines, and identifies gaps that could be addressed through a global regulatory science agenda. The article also identifies challenges to implementing a regulatory science agenda and proposes strategies and actions to fill these gaps. A global regulatory science agenda will enable

  14. Wetlands: The changing regulatory landscape

    SciTech Connect

    Glick, R.M. )

    1993-05-01

    Protection of wetlands became a national issue in 1988 when President George Bush pledged no net loss of wetlands in the US under his [open quotes]environmental presidency.[close quotes] As wetlands became a national issue, the job of protecting them became an obligation for many groups, including hydro-power developers. Now, when a site selected for development includes an area that may be classified as a wetland, the developer quickly discovers the importance of recognizing and protecting these natural habitats. Federal legislation severely limits development of wetland, and most states increase the restrictions with their own wetlands regulations. The difficulty of defining wetlands complicates federal and state enforcement. Land that appears to be dry may in fact be classified as a wetland. So, even if a site appears dry, potential hydro developers must confirm whether or not any jurisdictional wetlands are present. Regulated lands include much more than marshes and swamps. Further complicating the definition of wetlands, a recent court decision found that even artificially created wetlands, such as man-made ponds, may be subject to regulation. Hydro developers must be aware of current regulatory requirements before they consider development of any site that may contain wetlands. To be certain that a site is [open quotes]buildable[close quotes] from the standpoint of wetlands regulation, a developer must verify (with the help of state agencies) that the property does not contain any jurisdictional wetlands. If it does, the regulatory process before development becomes much more complicated. For the short term, uncertainty abounds and extreme caution is in order. Because the regulatory process has become so complex and an agreeable definition of wetlands so elusive, the trend among the Corps and collaborating agencies is to constrict nationwide permits in favor of narrowing the jurisdictional definition of wetlands.

  15. Human System Integration: Regulatory Analysis

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This document was intended as an input to the Access 5 Policy Integrated Product team. Using a Human System Integration (HIS) perspective, a regulatory analyses of the FARS (specifically Part 91), the Airman s Information Manual (AIM) and the FAA Controllers Handbook (7110.65) was conducted as part of a front-end approach needed to derive HSI requirements for Unmanned Aircraft Systems (UAS) operations in the National Airspace System above FL430. The review of the above aviation reference materials yielded eighty-four functions determined to be necessary or highly desirable for flight within the Air Traffic Management System. They include categories for Flight, Communications, Navigation, Surveillance, and Hazard Avoidance.

  16. Fayette County Better Buildings Initiative

    SciTech Connect

    Capella, Arthur

    2015-03-04

    The Fayette County Better Buildings Initiative represented a comprehensive and collaborative approach to promoting and implementing energy efficiency improvements. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. The ultimate goal of Fayette County’s Better Buildings Initiative was to implement a total of 1,067 residential energy efficiency retrofits with a minimum 15% estimated energy efficiency savings per unit. Program partners included: United States Department of Energy, Allegheny Power, and Private Industry Council of Westmoreland-Fayette, Fayette County Redevelopment Authority, and various local partners. The program was open to any Fayette County residents who own their home and meet the prequalifying conditions. The level of assistance offered depended upon household income and commitment to undergo a BPI – Certified Audit and implement energy efficiency measures, which aimed to result in at least a 15% reduction in energy usage. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. Additionally, the program had components that involved recruitment and training for employment of persons in the energy sector (green jobs), as well as marketing and implementation of a commercial or community facilities component. The residential component of Fayette County’s Better Buildings Initiative involved a comprehensive approach, providing assistance to low- moderate- and market-rate homeowners. The initiative will also coordinate activities with local utility providers to further incentivize energy efficiency improvements among qualifying homeowners. The commercial component of Fayette County’s Better Building Initiative involved grants

  17. Regulatory RNAs in photosynthetic cyanobacteria.

    PubMed

    Kopf, Matthias; Hess, Wolfgang R

    2015-05-01

    Regulatory RNAs play versatile roles in bacteria in the coordination of gene expression during various physiological processes, especially during stress adaptation. Photosynthetic bacteria use sunlight as their major energy source. Therefore, they are particularly vulnerable to the damaging effects of excess light or UV irradiation. In addition, like all bacteria, photosynthetic bacteria must adapt to limiting nutrient concentrations and abiotic and biotic stress factors. Transcriptome analyses have identified hundreds of potential regulatory small RNAs (sRNAs) in model cyanobacteria such as Synechocystis sp. PCC 6803 or Anabaena sp. PCC 7120, and in environmentally relevant genera such as Trichodesmium, Synechococcus and Prochlorococcus. Some sRNAs have been shown to actually contain μORFs and encode short proteins. Examples include the 40-amino-acid product of the sml0013 gene, which encodes the NdhP subunit of the NDH1 complex. In contrast, the functional characterization of the non-coding sRNA PsrR1 revealed that the 131 nt long sRNA controls photosynthetic functions by targeting multiple mRNAs, providing a paradigm for sRNA functions in photosynthetic bacteria. We suggest that actuatons comprise a new class of genetic elements in which an sRNA gene is inserted upstream of a coding region to modify or enable transcription of that region.

  18. RSAT: regulatory sequence analysis tools.

    PubMed

    Thomas-Chollier, Morgane; Sand, Olivier; Turatsinze, Jean-Valéry; Janky, Rekin's; Defrance, Matthieu; Vervisch, Eric; Brohée, Sylvain; van Helden, Jacques

    2008-07-01

    The regulatory sequence analysis tools (RSAT, http://rsat.ulb.ac.be/rsat/) is a software suite that integrates a wide collection of modular tools for the detection of cis-regulatory elements in genome sequences. The suite includes programs for sequence retrieval, pattern discovery, phylogenetic footprint detection, pattern matching, genome scanning and feature map drawing. Random controls can be performed with random gene selections or by generating random sequences according to a variety of background models (Bernoulli, Markov). Beyond the original word-based pattern-discovery tools (oligo-analysis and dyad-analysis), we recently added a battery of tools for matrix-based detection of cis-acting elements, with some original features (adaptive background models, Markov-chain estimation of P-values) that do not exist in other matrix-based scanning tools. The web server offers an intuitive interface, where each program can be accessed either separately or connected to the other tools. In addition, the tools are now available as web services, enabling their integration in programmatic workflows. Genomes are regularly updated from various genome repositories (NCBI and EnsEMBL) and 682 organisms are currently supported. Since 1998, the tools have been used by several hundreds of researchers from all over the world. Several predictions made with RSAT were validated experimentally and published.

  19. Nolley v. County of Erie.

    PubMed

    1991-10-31

    The U.S. District Court, Western District of New York, held that the Erie County Holding Center (ECHC) had violated an HIV-positive inmate's privacy rights under the U.S. Constitution and the New York Public Health Law by placing red stickers on the inmate's paperwork and belongings, and by segregating her from the general inmate population. The court reasoned that, pursuant to the federal Centers for Disease Control's recommendation that corrections staff take HIV precautions with all inmates, the ECHC's treatment constituted an unjustifiable isolation based solely on her HIV status. The court also held that the ECHC further violated the inmate's constitutional rights by denying her access to the law library and to religious services. Although the court found the inmate's incarceration conditions "deplorable," the conditions did not constitute "cruel and unusual punishment." The court also found no federal Rehabilitation Act violation because the ECHC did not receive federal financial assistance.

  20. Hydrologic conditions: Dade County, Florida

    USGS Publications Warehouse

    Kohout, Francis Anthony; Klein, Howard; Sherwood, C.B.; Leach, Stanley D.

    1964-01-01

    Thin layers of dense limestone of low permeability that occur near the top of the Biscayne aquifer in the vicinity of the north end of Levee 30 in Dade County, Florida are of hydrologic importance because they retard the downward infiltration of ponded water in Conservation Area No. 3. This retarding effect frequently results in high head differentials across the levee. Tests made in a small area adjacent to Levee 30 indicate that the coefficient of transmissibility of the aquifer is 3,600,000 gpd (gallons per day) per foot, and the coefficient of vertical permeability of the dense limestones is 13 gpd per square foot. If ground-water flow beneath the levee is laminar, the total inflow to the Levee 30 Canal from Conservation Area No. 3 will be about 350 mgd (million gallons per day), or 540 cfs (cubic feet per second), per mile length of levee when the head difference across the levee is 10 feet.

  1. Costilla County Biodiesel Pilot Project

    SciTech Connect

    Doon, Ben; Quintana, Dan

    2011-08-25

    The Costilla County Biodiesel Pilot Project has demonstrated the compatibility of biodiesel technology and economics on a local scale. The project has been committed to making homegrown biodiesel a viable form of community economic development. The project has benefited by reducing risks by building the facility gradually and avoiding large initial outlays of money for facilities and technologies. A primary advantage of this type of community-scale biodiesel production is that it allows for a relatively independent, local solution to fuel production. Successfully using locally sourced feedstocks and putting the fuel into local use emphasizes the feasibility of different business models under the biodiesel tent and that there is more than just a one size fits all template for successful biodiesel production.

  2. [Advanced therapy: from European regulatory framework to national regulatory framework].

    PubMed

    Lucas-Samuel, S

    2013-05-01

    The European regulation n(o) 1394/2007/CE published on the 13th of November 2007 defined and harmonized the European regulatory framework for advanced therapy medicinal products. It creates a specialized committee located at the European Medicine Agency, in charge of the assessment of these medicinal products. The consequences of this regulation are introduced in the French regulation by the law n(o) 2011-302 published on the 22nd of March 2011. It detailed notably the possibility for public establishments (except health establishments) and nonprofit organisms to create pharmaceutical establishments. This law defined also a specific category of advanced therapy medicinal products, which fall under the "hospital exemption" framework. The rules regarding the authorizations of the establishments able to prepare these types of medicinal products and the authorization of the products are defined by the n(o) 2012-1236 decree published on the 6th of November 2012.

  3. Global Summit on Regulatory Science 2013.

    PubMed

    Howard, Paul C; Tong, Weida; Weichold, Frank; Healy, Marion; Slikker, William

    2014-12-01

    Regulatory science has been defined as the science that is used to develop regulatory decisions by government bodies. Regulatory science encompasses many scientific disciplines that oversee many studies producing a wide array of data. These may include fundamental research into the cellular interaction or response to a particular chemical or substance, hazard-assessment and dose-response studies in animal species, neurophysiological or neurobehavioral studies, best practices for the generation and analysis of genomics data, bioinformatics approaches, and mathematical modeling of risk. The Global Summit on Regulatory Science is an international conference with a mission to explore emerging and innovative technologies, and provide a platform to enhance translation of basic science into regulatory applications. The Third Global Summit on Regulatory Science which focused on nanotechnology is discussed.

  4. Computer Technology in Rural Schools: The Case of Mendocino County.

    ERIC Educational Resources Information Center

    Hoachlander, E. Gareth

    The county education office of Mendocino County, California, serving nine school districts and 11,800 elementary and secondary students, began planning for computers in 1979-1980, purchased two central computers, and by 1983 had one computer or terminal for every 40 students in the county. The county was characterized by its very enthusiastic…

  5. Evaluation of the Union County Alternative to Suspension Program

    ERIC Educational Resources Information Center

    Dunlap, Joyce Ann

    2010-01-01

    The schools in Union County have undergone a tremendous amount of growth in the past decade. The growth in the county has led to an increase in discipline problems. In order to provide suspended students a second chance, Union County Public Schools implemented an alternative to suspension program, the Union County Alternative to Suspension Program…

  6. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  7. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  8. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  9. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  10. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  11. 7 CFR 1230.634 - FSA county office report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CONSUMER INFORMATION Procedures for the Conduct of Referendum Referendum § 1230.634 FSA county office report. The FSA county office will notify the FSA State office of the results of the referendum. Each FSA county office will transmit the results of the referendum in its county to the FSA State office....

  12. 7 CFR 1230.634 - FSA county office report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CONSUMER INFORMATION Procedures for the Conduct of Referendum Referendum § 1230.634 FSA county office report. The FSA county office will notify the FSA State office of the results of the referendum. Each FSA county office will transmit the results of the referendum in its county to the FSA State office....

  13. 1918 Influenza: A Winnebago County, Wisconsin Perspective

    PubMed Central

    Shors, Teri; McFadden, Susan H.

    2009-01-01

    The population of Winnebago County in 1918 was approximately 62,000 residents. It consisted of towns supporting diverse manufacturers surrounded by farming country. For this study, records were revisited, and 1918 to 1920 influenza survivors were interviewed. A pharmacological investigation encompassing the various influenza treatments used in Wisconsin from 1918 to 1920 was documented. In 1918, over 180 individuals perished from influenza, and over 2000 cases were reported in Winnebago County, Wisconsin. Influenza returned in 1920, which some researchers refer to as the “fourth wave,” claiming nearly 50 lives in Winnebago County, Wisconsin. This study also documents the 1920 influenza wave. PMID:19889943

  14. Drainage basins in Duval County, Florida

    USGS Publications Warehouse

    Stone, Roy B.; Largen, Joseph B.

    1983-01-01

    The drainage basins and subbasins in Duval County, Florida, are delineated on this atlas map. The county 's 840 square-mile area is drained by three major river systems; the St. Johns, 668 square miles; Nassau, 113 square miles; and St. Marys, 59 square miles. The remainder of the county is drained by a network of small streams that flow into either the Intracoastal Waterway or directly into the Atlantic Ocean. The sub-basins range in size from less than one square mile to more than 50 square miles. (USGS)

  15. Tri-county pilot study. [Texas

    NASA Technical Reports Server (NTRS)

    Reeves, C. A. (Principal Investigator); Austin, T. W.; Kerber, A. G.

    1976-01-01

    The author has identified the following significant results. An area inventory was performed for three southeast Texas counties (Montgomery, Walker, and San Jacinto) totaling 0.65 million hectares. The inventory was performed using a two level hierarchy. Level 1 was divided into forestland, rangeland, and other land. Forestland was separated into Level 2 categories: pine, hardwood, and mixed; rangeland was not separated further. Results consisted of area statistics for each county and for the entire study site for pine, hardwood, mixed, rangeland, and other land. Color coded county classification maps were produced for the May data set, and procedures were developed and tested.

  16. County/private partnership expedites recycling

    SciTech Connect

    Not Available

    1994-03-01

    This article describes how Broward County, Florida and Browning-Ferris Industries (Houston, Texas) implemented a highly accelerated recycling project that had a county-wide recycling system fully operational in 180 days. The program is a strong step toward speeding compliance with Florida's mandated 30 percent recycling goal. The 1.2 million citizens in Broward County began recycling materials in dual curbside bins October 1, 1993. Previously, the participating communities all acted autonomously. Minimal volumes of newspaper, aluminum, clear glass, and some plastic were collected by curbsort vehicles and processed at small local recycling centers.

  17. Environmental Regulatory Update Table, January 1991

    SciTech Connect

    Hawkins, G.T.; Houlberg, L.M.; Salk, M.S.

    1991-02-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  18. Environmental regulatory update table, March 1989

    SciTech Connect

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-04-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  19. Environmental regulatory update table, July 1991

    SciTech Connect

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-08-01

    This Environmental Regulatory Update Table (July 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  20. Environmental Regulatory Update Table, December 1990

    SciTech Connect

    Hawkins, G.T.; Houlberg, L.M.; Noghrei-Nikbakht, P.A.; Salk, M.S.

    1991-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  1. Environmental Regulatory Update Table, November 1990

    SciTech Connect

    Hawkins, G.T.; Houlberg, L.M.; Noghrei-Nikbakht, P.A.; Salk, M.S.

    1990-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  2. Environmental Regulatory Update Table, September 1990

    SciTech Connect

    Houlberg, L.M.; Nikbakht, A.; Salk, M.S.

    1990-10-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  3. Environmental Regulatory Update Table, October 1991

    SciTech Connect

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  4. Environmental Regulatory Update Table, October 1990

    SciTech Connect

    Houlberg, L.M.; Noghrei-Nikbakht, P.A.; Salk, M.S.

    1990-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  5. Environmental Regulatory Update Table, April 1989

    SciTech Connect

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  6. Environmental Regulatory Update Table, December 1989

    SciTech Connect

    Houlbert, L.M.; Langston, M.E. ); Nikbakht, A.; Salk, M.S. )

    1990-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  7. Environmental Regulatory Update Table, August 1991

    SciTech Connect

    Houlberg, L.M., Hawkins, G.T.; Salk, M.S.

    1991-09-01

    This Environmental Regulatory Update Table (August 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  8. Environmental Regulatory Update Table, December 1991

    SciTech Connect

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  9. Environmental Regulatory Update Table, November 1991

    SciTech Connect

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  10. Environmental Regulatory Update Table, September 1991

    SciTech Connect

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-10-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  11. Lea County 001, an H5 chondrite, and Lea County 002, an ungrouped type 3 chondrite

    SciTech Connect

    Zolensky, M.E.; Score, R.; Clayton, R.N.; Mayeda, T.K.; Schutt, J.W. Lockheed Engineering and Sciences Co., Houston, TX Chicago Univ., IL )

    1989-12-01

    A search of active deflation basins near Jal, Lea County, New Mexico resulted in the discovery of two meteorites, Lea County 001 and 002. Lea County 001 has mean olivine and low-Ca pyroxene compositions of Fa(19) and Fs(17), respectively. These and all other mineralogical and petrological data collected indicate a classification of H5 for this stone. Lea County 002 has mean olivine and low-Ca pyroxene compositions of Fa(2) and Fs(4), and is unequilibrated. Although it is mineralogically most similar to Kakangari and chondritic clasts within Cumberland Falls, the high modal amount of forsterite makes Lea County a unique type 3 chondrite. Oxygen isotope data for Lea County 002 fall on an 0-16-mixing line through those of the enstatite meteorites and IAB irons, a feature shared by Kakangari. 28 refs.

  12. Characteristics of the Las Vegas/Clark County visitor economy

    SciTech Connect

    1988-06-01

    The purpose of this report is to present the results of a review of the Clark County visitor economy and the Clark County visitor. The review, undertaken in support of NWPO`s two objectives mentioned above, addressed a number of topics including performance of the Clark County visitor economy as a generator of employment, earnings and tax base; importance of the Clark County visitor economy to the Nevada economy as a whole; elements of the Clark County visitor economy outside the Las Vegas strip and downtown areas; current trends in the Clark County visitor industry; and indirect economic effects of Clark County casino/hotel purchases.

  13. 21 CFR 26.18 - Regulatory collaboration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... Specific Sector Provisions for Pharmaceutical Good Manufacturing Practices § 26.18 Regulatory...

  14. A genomic regulatory network for development

    NASA Technical Reports Server (NTRS)

    Davidson, Eric H.; Rast, Jonathan P.; Oliveri, Paola; Ransick, Andrew; Calestani, Cristina; Yuh, Chiou-Hwa; Minokawa, Takuya; Amore, Gabriele; Hinman, Veronica; Arenas-Mena, Cesar; Otim, Ochan; Brown, C. Titus; Livi, Carolina B.; Lee, Pei Yun; Revilla, Roger; Rust, Alistair G.; Pan, Zheng jun; Schilstra, Maria J.; Clarke, Peter J C.; Arnone, Maria I.; Rowen, Lee; Cameron, R. Andrew; McClay, David R.; Hood, Leroy; Bolouri, Hamid

    2002-01-01

    Development of the body plan is controlled by large networks of regulatory genes. A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here. The network was derived from large-scale perturbation analyses, in combination with computational methodologies, genomic data, cis-regulatory analysis, and molecular embryology. The network contains over 40 genes at present, and each node can be directly verified at the DNA sequence level by cis-regulatory analysis. Its architecture reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.

  15. Immunometabolism of regulatory T cells

    PubMed Central

    Newton, Ryan; Priyadharshini, Bhavana; Turka, Laurence A

    2016-01-01

    The bidirectional interaction between the immune system and whole-body metabolism has been well recognized for many years. Via effects on adipocytes and hepatocytes, immune cells can modulate whole-body metabolism (in metabolic syndromes such as type 2 diabetes and obesity) and, reciprocally, host nutrition and commensal-microbiota-derived metabolites modulate immunological homeostasis. Studies demonstrating the metabolic similarities of proliferating immune cells and cancer cells have helped give birth to the new field of immunometabolism, which focuses on how the cell-intrinsic metabolic properties of lymphocytes and macrophages can themselves dictate the fate and function of the cells and eventually shape an immune response. We focus on this aspect here, particularly as it relates to regulatory T cells. PMID:27196520

  16. Regulatory Analysis of Reactivity Transients

    SciTech Connect

    Beyer, Carl E.; Clifford, Paul M.; Geelhood, Kenneth J.; Voglewede, John C.

    2009-08-01

    This paper will describe modifications made to the FRAPCON-3 and FRAPTRAN fuel performance codes and models that impact reactivity initiated accident (RIA) analyses. The modified models include an upper bound empirical and best estimate release models for fast transients, and a revised fuel failure model that accounts for ductile and brittle failure. Because experimental data exists for discrete test conditions, the codes and models are used to interpolate and to some extent, to extrapolate these test conditions. An upper bound empirical model for release is used to establish new recommended release fractions for long-lived and short lived (radioactive) isotopes for RIA events in Regulatory Guide 1.183. A best estimate release model is used in FRAPTRAN 1.4 based on grain boundary gas concentrations from FRAPCON-3.4 to predict release for RIA events. Code and model predictions will be compared to failure and release data from RIA tests to demonstrate accuracy.

  17. 78 FR 60686 - Establishment of the Big Valley District-Lake County and Kelsey Bench-Lake County Viticultural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... on April 5, 2013 (78 FR 20544), proposing to establish the Big Valley District-Lake County and Kelsey... District-Lake County and Kelsey Bench-Lake County Viticultural Areas and Modification of the Red Hills Lake... approximately 11,000-acre ``Big Valley District-Lake County'' viticultural area and the approximately...

  18. 76 FR 30152 - East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... AGENCY East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of... response costs concerning the East Calloway County Middle School Mercury Spill Site located in Murray... Site name East Calloway County ] Middle School Mercury Spill Site by one of the following methods:...

  19. 75 FR 49016 - County of Greenville, S.C.-Acquisition Exemption-Greenville County Economic Development Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Greenville County Economic Development Corporation (GCEDC) approximately 11.8 miles of rail line between... accordance with the National Trails System Act, 16 U.S.C. 1247(d). See Greenville County Economic Development... Surface Transportation Board County of Greenville, S.C.--Acquisition Exemption--Greenville County...

  20. Regulatory aspects of clinical xenotransplantation.

    PubMed

    Schuurman, Henk-Jan

    2015-11-01

    Xenotransplantation attracted interest from regulatory authorities, particularly after the demonstration of pig-to-human transmission of porcine endogenous retrovirus (1996). This added to the risk of a product, resulting in a Guidance of the US Food and Drug Administration (2003). This addresses the full flow chart in product manufacturing, starting with the designated pathogen-free status of the source animal; and special aspects regarding the recipient like informed consent and monitoring for infectious pathogens. Also archiving of records from the donor and recipient, as well as storage of samples is described. The European Medicines Agency issued a Guideline on xenogeneic cell therapy products (2009). Cell-based medicinal products are subject to specific regulations and directives, which apply also to xenogeneic products: the xenotransplant guidances/guidelines are an addition to these regulations. Noteworthy, acellular products like heart valves and decellularized cornea are not considered a cell therapy product, but rather a medical device with its own regulation. WHO issued relevant documents, especially about safety, and the International Xenotransplantation Association published consensus documents, a.o., addressing preclinical efficacy requirements before entering clinical trials. This manuscript presents an overview of the regulatory framework, with special focus on cell therapy products necause these are expected to reach the market first (i.e., pancreatic islets, hepatocytes and cellularized cornea); major illustrations are from the European situation. Albeit being complex, the regulation of xenotransplant products does not form a block in product development, but rather supports the introduction of efficacious and safe products to meet the medical need.

  1. Small regulatory RNAs in Archaea.

    PubMed

    Babski, Julia; Maier, Lisa-Katharina; Heyer, Ruth; Jaschinski, Katharina; Prasse, Daniela; Jäger, Dominik; Randau, Lennart; Schmitz, Ruth A; Marchfelder, Anita; Soppa, Jörg

    2014-01-01

    Small regulatory RNAs (sRNAs) are universally distributed in all three domains of life, Archaea, Bacteria, and Eukaryotes. In bacteria, sRNAs typically function by binding near the translation start site of their target mRNAs and thereby inhibit or activate translation. In eukaryotes, miRNAs and siRNAs typically bind to the 3'-untranslated region (3'-UTR) of their target mRNAs and influence translation efficiency and/or mRNA stability. In archaea, sRNAs have been identified in all species investigated using bioinformatic approaches, RNomics, and RNA-Seq. Their size can vary significantly between less than 50 to more than 500 nucleotides. Differential expression of sRNA genes has been studied using northern blot analysis, microarrays, and RNA-Seq. In addition, biological functions have been unraveled by genetic approaches, i.e., by characterization of designed mutants. As in bacteria, it was revealed that archaeal sRNAs are involved in many biological processes, including metabolic regulation, adaptation to extreme conditions, stress responses, and even in regulation of morphology and cellular behavior. Recently, the first target mRNAs were identified in archaea, including one sRNA that binds to the 5'-region of two mRNAs in Methanosarcina mazei Gö1 and a few sRNAs that bind to 3'-UTRs in Sulfolobus solfataricus, three Pyrobaculum species, and Haloferax volcanii, indicating that archaeal sRNAs appear to be able to target both the 5'-UTR or the 3'-UTRs of their respective target mRNAs. In addition, archaea contain tRNA-derived fragments (tRFs), and one tRF has been identified as a major ribosome-binding sRNA in H. volcanii, which downregulates translation in response to stress. Besides regulatory sRNAs, archaea contain further classes of sRNAs, e.g., CRISPR RNAs (crRNAs) and snoRNAs.

  2. 69. MISSISSIPPI, LOWNDES CO. COLUMBUS MAP OF LOWNDES COUNTY, 1931 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    69. MISSISSIPPI, LOWNDES CO. COLUMBUS MAP OF LOWNDES COUNTY, 1931 ROAD MAP OF LOWNDES COUNTY, MISSISSIPPI, 1931 by C.L. Wood, the county engineer. Updated through the mid-1930s to show new federal aid-state roads. Compares modern system with older county system. Original scale: 1 in. to 1 mi. Property of Helen (Mrs. Sam L.) Crawford, Hamilton, Ms. Sarcone Photography, Columbus, Ms., Sep 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  3. Multipurpose Centers in a Rural County.

    ERIC Educational Resources Information Center

    Norris, Jean

    1978-01-01

    Describes services, programs, and funding for the various senior centers in Frankin County, New York, which has a predominately rural, low-income population. Services include bus transportation, nutrition programs, health and financial assistance, and social events. (MF)

  4. Model county ordinance for wind projects

    SciTech Connect

    Bain, D.A.

    1997-12-31

    Permitting is a crucial step in the development cycle of a wind project and permits affect the timing, cost, location, feasibility, layout, and impacts of wind projects. Counties often have the lead responsibility for permitting yet few have appropriate siting regulations for wind projects. A model ordinance allows a county to quickly adopt appropriate permitting procedures. The model county wind ordinance developed for use by northwest states is generally applicable across the country and counties seeking to adopt siting or zoning regulations for wind will find it a good starting place. The model includes permitting procedures for wind measurement devices and two types of wind systems. Both discretionary and nondiscretionary standards apply to wind systems and a conditional use permit would be issued. The standards, criteria, conditions for approval, and process procedures are defined for each. Adaptation examples for the four northwest states are provided along with a model Wind Resource Overlay Zone.

  5. Surface-water availability, Tuscaloosa County, Alabama

    USGS Publications Warehouse

    Knight, Alfred L.; Davis, Marvin E.

    1975-01-01

    The average annual runoff, about 1,270 mgd (million gallons per day), originating in Tuscaloosa County is equivalent to 20 inches or 0.95 mgd per square mile. The Black Warrior and Sipsey Rivers, the largest streams in the county, have average flows of 5,230 mgd and 580 mgd, respectively, where they leave the county, and median annual 7-day low flows in excess of 150 mgd and 35 mgd, respectively. North River, Big Sandy Creek, and Hurricane Creek have average flows in excess of 100 mgd and median annual 7-day low flows in excess of 2 mgd. Surface water generally contains less than 100 mg/l (milligrams per liter) dissolved solids, less than 10 mg/l chloride, and is soft to moderately hard. Streams having the higher hardness and the higher dissolved-solids content are in eastern Tuscaloosa County.

  6. Charging Up in King County, Washington

    ScienceCinema

    Constantine, Dow; Oliver, LeAnn; Inslee, Jay; Sahandy, Sheida; Posthuma, Ron; Morrison, David

    2016-07-12

    King County, Washington is spearheading a regional effort to develop a network of electric vehicle charging stations. It is also improving its vehicle fleet and made significant improvements to a low-income senior housing development.

  7. Environmental assessment: Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified a location in Deaf Smith County, Texas, as one of the nine potentially acceptable sites for mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Deaf Smith County site and eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. The Deaf Smith County site is in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. On the basis of the evaluations reported in this EA, the DOE has found that the Deaf Smith County site is not disqualified under the guidelines.

  8. Charging Up in King County, Washington

    SciTech Connect

    Constantine, Dow; Oliver, LeAnn; Inslee, Jay; Sahandy, Sheida; Posthuma, Ron; Morrison, David

    2011-01-01

    King County, Washington is spearheading a regional effort to develop a network of electric vehicle charging stations. It is also improving its vehicle fleet and made significant improvements to a low-income senior housing development.

  9. A Seniors' Program for Beaver County

    ERIC Educational Resources Information Center

    Taylor, Donald F.

    1973-01-01

    Programs for seniors are needed, according to the assistant director of continuing education at the Community College of Beaver County (Pennsylvania); the question revolves around who will pay. (Editor)

  10. 7 CFR 718.8 - Administrative county.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING QUOTAS, ACREAGE ALLOTMENTS, AND PRODUCTION ADJUSTMENT PROVISIONS APPLICABLE TO MULTIPLE PROGRAMS... located in the county where the principal dwelling is situated, or where the major portion of the farm...

  11. Environmental assessment, Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    The Nuclear Waste Policy Act of 1982 (42 USC sections 10101-10226) requires the environmental assessment of a proposed site to include a statement of the basis for nominating a site as suitable for characterization. Volume 2 provides a detailed statement evaluating the site suitability of the Deaf Smith County Site under DOE siting guidelines, as well as a comparison of the Deaf Smith County Site to the other sites under consideration. The evaluation of the Deaf Smith County Site is based on the impacts associated with the reference repository design, but the evaluation will not change if based on the Mission Plan repository concept. The second part of this document compares the Deaf Smith County Site to Davis Canyon, Hanford, Richton Dome and Yucca Mountain. This comparison is required under DOE guidelines and is not intended to directly support subsequent recommendation of three sites for characterization as candidate sites. 259 refs., 29 figs., 66 refs. (MHB)

  12. Hydrogeology of Cibola County, New Mexico

    USGS Publications Warehouse

    Baldwin, J.A.; Rankin, D.R.

    1995-01-01

    The hydrogeology of Cibola County, New Mexico, was evaluated to determine the occurrence, availability, and quality of ground-water resources. Rocks of Precambrian through Quaternary age are present in Cibola County. Most rocks are sedimentary in origin except for Precambrian igneous and metamorphic rocks exposed in the Zuni Uplift and Tertiary and Quaternary basalts in northern and central parts of the county. The most productive aquifers in the county include (youngest to oldest) Quaternary deposits, sandstones in the Mesaverde Group, the Dakota-Zuni-Bluff aquifer, the Westwater Canyon aquifer, the Todilto- Entrada aquifer, sandstone beds in the Chinle Formation, and the San Andres-Glorieta aquifer. Unconsolidated sand, silt, and gravel form a mantle ranging from a few inches to 150 to 200 feet over much of the bedrock in Cibola County. Well yields range from 5 to 1,110 gallons per minute. Dissolved-solids concentrations of ground water range from 200 to more than 5,200 milligrams per liter. Calcium, magnesium, bicarbonate, and sulfate are the predominant ions in ground water in alluvial material. The Mesaverde Group mainly occurs in three areas of the county. Well yields range from less than 1 to 12 gallons per minute. The predominant ions in water from wells in the Mesaverde Group are calcium, sodium, and bicarbonate. The transition from calcium-predominant to sodium-predominant water in the southwestern part of the county likely is a result of ion exchange. Wells completed in the Dakota-Zuni-Bluff aquifer yield from 1 to 30 gallons per minute. Dissolved-solids concentrations range from 220 to 2,000 milligrams per liter in water from 34 wells in the western part of the county. Predominant ions in the ground water include calcium, sodium, sulfate, and bicarbonate. Calcium predominates in areas where the aquifer is exposed at the surface or is overlain with alluvium. Sandstones in the Chinle Formation yield from 10 to 300 gallons per minute to wells in the Grants

  13. Regulatory fit messages and physical activity motivation.

    PubMed

    Pfeffer, Ines

    2013-04-01

    Targeted communication about health behaviors seems to be more effective than mass communication in which undifferentiated audiences receive identical messages. Regulatory focus is psychological variable that can be used to build two target groups: promotion-focused or prevention-focused people. It is hypothesized that targeting messages to an individual's regulatory focus creates regulatory fit and is more successful to promote a physically active lifestyle than nonfit messages. Two different print messages promoting a physically active lifestyle derived from regulatory focus theory (promotion message vs. prevention message) were randomly assigned to N = 98 participants after measuring their regulatory focus. It was examined whether regulatory fit between the regulatory focus and the assigned print message would lead to more positive evaluations in the dependent variables inclination toward the message (preference for the message), intention to perform the behavior, prospective and retrospective feelings associated with the behavior (positive and negative), and perceived value of the behavior directly after reading the message. Hierarchical linear regression analyses revealed that regulatory fit led to stronger intentions in the prevention-message condition and more prospective positive and retrospective positive feelings associated with the behavior in the promotion-message condition in contrast to the nonfit conditions. Prospective positive feelings associated with the behavior mediated the effect of regulatory fit on intention. The results partly provided support for the regulatory fit concept. Matching print messages to the regulatory focus of individuals seems to be a useful approach to enhance physical activity motivation. Future studies should include an objective measure of physical activity behavior.

  14. SOLAR PANELS ON HUDSON COUNTY FACILITIES

    SciTech Connect

    BARRY, KEVIN

    2014-06-06

    This project involved the installation of an 83 kW grid-connected photovoltaic system tied into the energy management system of Hudson County's new 60,000 square foot Emergency Operations and Command Center and staff offices. Other renewable energy features of the building include a 15 kW wind turbine, geothermal heating and cooling, natural daylighting, natural ventilation, gray water plumbing system and a green roof. The County intends to seek Silver LEED certification for the facility.

  15. The Water Cycle in Volusia County

    USGS Publications Warehouse

    German, Edward R.

    2009-01-01

    Earth's water is always in motion. The water cycle, also known as the hydrologic cycle, describes the continuous movement of water on, above, and below the Earth's surface. This fact sheet provides information about how much water moves into and out of Volusia County, and where it is stored. It also illustrates the seasonal variation in water quantity and movement using data from some of the hydrologic data collection sites in or near Volusia County, Florida.

  16. 75 FR 71166 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... thereunder,\\2\\ notice is hereby given that on November 1, 2010, Financial Industry Regulatory Authority, Inc... similar status or performing similar functions, or a natural person engaged in the investment banking...

  17. 76 FR 59751 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and... thereunder,\\2\\ notice is hereby given that on September 7, 2011, Financial Industry Regulatory Authority, Inc...), or are subject to a separate registration and qualification requirement, Investment...

  18. 77 FR 61647 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... turn transactions in security futures. \\12\\ 15 U.S.C. 78o-3(b)(5). B. Self-Regulatory Organization's... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and... in Security Futures October 3, 2012. Pursuant to Section 19(b)(1) of the Securities Exchange Act...

  19. 75 FR 53998 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-02

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Amend the Security Futures Risk Disclosure Statement.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of...

  20. 76 FR 37384 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change Relating to Exemptions from the Order Audit Trail System..., Financial Industry Regulatory Authority, Inc. (``FINRA'') filed with the Securities and Exchange...

  1. 76 FR 60567 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... Reporting Rules for Certain Alternative Trading Systems September 23, 2011. Pursuant to Section 19(b)(1) of... that on September 16, 2011, the Financial Industry Regulatory Authority, Inc. (``FINRA'') filed...

  2. 76 FR 71404 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change Relating to the Order Audit Trail System Definitions of... November 4, 2011, Financial Industry Regulatory Authority, Inc. (``FINRA'') filed with the Securities...

  3. 78 FR 30384 - Federal Regulatory Enforcement Fairness Hearing; Region X Regulatory Fairness Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... ADMINISTRATION Federal Regulatory Enforcement Fairness Hearing; Region X Regulatory Fairness Board AGENCY: U.S. Small Business Administration (SBA). ACTION: Notice of open meeting of the Regional (Region X) Small... requested. Anyone wishing to attend and/or make a presentation to the Region X Regulatory Fairness...

  4. 77 FR 14052 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... Change in Ownership, Control, or Business Operations) To Adopt New Standardized Electronic Form CMA March.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of...

  5. 75 FR 39603 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving... Exchange Act Release No. 61189 (December 17, 2009), 74 FR 68648 (``Notice''). \\4\\ See Letter to Elizabeth M... obligations, if applicable, to the Commission or other regulatory authority; (3) FINRA has actual...

  6. 75 FR 49542 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of... 19b-4 thereunder,\\2\\ notice is hereby given that on July 27, 2010, Financial Industry Regulatory... members in a timely fashion to facilitate its Regulation M compliance program. Rule 5190(d) sets forth...

  7. 75 FR 74766 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and..., Financial Industry Regulatory Authority, Inc. (``FINRA'') filed with the Securities and Exchange Commission...\\ See Exchange Act Release No. 62434 (July 1, 2010; 75 FR 39603 (July 9, 2010); SR-FINRA-2009-089...

  8. The flora of Oktibbeha County, Mississippi

    USGS Publications Warehouse

    Leidolf, A.; McDaniel, S.; Nuttle, T.

    2002-01-01

    We surveyed the flora of Oktibbeha County, Mississippi, U.S.A., from February 1994 to 1996. Occupying 118 square kilometers in east-central Mississippi, Oktibbeha County lies among 3 physiographic regions that include, from west to east, Interior Flatwoods, Pontotoc Ridge, and Black Prairie. Accordingly, the county harbors a diverse flora. Based on field work, as well as an extensive review of published literature and herbarium records at IBE and MISSA, we recorded a total of 1,148 taxa (1,125 species, 7 hybrids, 16 infraspecific taxa) belonging to 514 genera in 160 families, over 85% of all taxa documented were native. Compared to 3 other counties in east-central Mississippi, Oktibbeha County has the second largest recorded flora. The number of state-listed (endangered, threatened, or of special concern) taxa (67) documented in this survey far exceeds that reported from any other county in the region. Three introduced species, Ilex cornuta Lindl. & Paxton, Mahonia bealei (Fortune) Carrie??re, and Nandina domestica Thunb., are reported in a naturalized state for the first time from Mississippi. We also describe 16 different plant communities belonging to 5 broad habitat categories: bottomland forests, upland forests and prairies, aquatic habitats, seepage areas, and human-influenced habitats. A detailed description of the vegetation associated with each of these communities is provided.

  9. Department of Labor Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Date FR Cite ANPRM 12/00/10 Regulatory Flexibility Analysis Required: Undetermined Government Levels...: Action Date FR Cite NPRM 12/00/10 Regulatory Flexibility Analysis Required: Undetermined Government..., 202, 205, 211, 301, 302, and 303 of EO 11246, as amended; 30 FR 12319; 32 FR 14303, as amended by...

  10. 47 CFR 101.533 - Regulatory status.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Regulatory status. 101.533 Section 101.533 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES 24 GHz Service and Digital Electronic Message Service § 101.533 Regulatory status. (a)...

  11. 47 CFR 101.533 - Regulatory status.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Regulatory status. 101.533 Section 101.533 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES 24 GHz Service and Digital Electronic Message Service § 101.533 Regulatory status. (a)...

  12. 47 CFR 27.10 - Regulatory status.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Regulatory status. 27.10 Section 27.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Applications and Licenses § 27.10 Regulatory status. The following rules apply...

  13. 47 CFR 27.10 - Regulatory status.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Regulatory status. 27.10 Section 27.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Applications and Licenses § 27.10 Regulatory status. The following rules apply...

  14. 47 CFR 27.10 - Regulatory status.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Regulatory status. 27.10 Section 27.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Applications and Licenses § 27.10 Regulatory status. The following rules apply...

  15. 47 CFR 90.1309 - Regulatory status.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Regulatory status. 90.1309 Section 90.1309 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Wireless Broadband Services in the 3650-3700 MHz Band § 90.1309 Regulatory...

  16. 47 CFR 27.10 - Regulatory status.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Regulatory status. 27.10 Section 27.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Applications and Licenses § 27.10 Regulatory status. The following rules apply...

  17. 47 CFR 27.10 - Regulatory status.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Regulatory status. 27.10 Section 27.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Applications and Licenses § 27.10 Regulatory status. The following rules apply...

  18. Department of Transportation Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... continues to have a SEIOSNOSE. Amendment No. 125-10 Amendment No. 125-10 required digital flight data... with Executive Order 12866 ``Regulatory Planning and Review'' (58 FR 51735; October 4, 1993) and the Department's Regulatory Policies and Procedures (44 FR 11034; February 26, 1979), the Department prepares...

  19. Federal Trade Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... and Review'' of September 30, 1993, 58 FR 51735 (Oct. 4, 1993). This edition of the Unified Agenda of..., ``Federalism,'' of August 4, 1999, 64 FR 43255 (Aug. 10, 1999), which does not apply to independent regulatory...'s Telemarketing Sales Rule (TSR or Rule) to address the sale of debt relief services (74 FR...

  20. 5 CFR 340.201 - Regulatory requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 340.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS OTHER THAN FULL-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.201 Regulatory requirements. This subpart contains the regulations of...

  1. 5 CFR 340.201 - Regulatory requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 340.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS OTHER THAN FULL-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.201 Regulatory requirements. This subpart contains the regulations of...

  2. Department of Defense Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... American Act. Timetable: Action Date FR Cite NPRM 06/00/10 Regulatory Flexibility Analysis Required: Yes... DoD oversight of contractor business systems. Timetable: Action Date FR Cite NPRM 01/15/10 75 FR 2457... Part V Department of Defense Semiannual Regulatory Agenda ] DEPARTMENT OF DEFENSE (DOD)...

  3. Environmental Protection Agency Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...:// Not in FR www.epa.gov/lawsregs/search/regagenda.html Semiannual Regulatory Flexibility Agenda www....html issue ] Monthly Action Initiation List http://www.regulations.gov/fdmspublic/component/ Not in FR... Rulemaking Gateway www.epa.gov/rulemaking/ Not in FR B. What Are EPA's Regulatory Goals, and What...

  4. 75 FR 79843 - Fall 2010 Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Locations Location Semiannual Regulatory Agenda www.reginfo.gov/, www.regulations.gov, and http:// Not in FR.../component/ Not in FR main?main=DocketDetail& d=EPA-HQ-OA-2008-0265 and http:// www.epa.gov/lawsregs/ search/ail.html Rulemaking Gateway www.epa.gov/rulemaking/ Not in FR B. What Are EPA's Regulatory...

  5. 5 CFR 847.102 - Regulatory structure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Regulatory structure. 847.102 Section 847.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... INSTRUMENTALITIES General Provisions § 847.102 Regulatory structure. (a)(1) Subpart A of this part...

  6. 40 CFR 92.6 - Regulatory structure.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and locomotive engines for which the regulations of this part (i.e., 40 CFR part 92) apply are... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Regulatory structure. 92.6 Section 92.6... Locomotives and Locomotive Engines § 92.6 Regulatory structure. This section provides an overview of...

  7. 5 CFR 847.102 - Regulatory structure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Regulatory structure. 847.102 Section 847.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... INSTRUMENTALITIES General Provisions § 847.102 Regulatory structure. (a)(1) Subpart A of this part...

  8. 40 CFR 92.6 - Regulatory structure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... locomotives and locomotive engines for which the regulations of this part (i.e., 40 CFR part 92) apply are... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Regulatory structure. 92.6 Section 92... Regulations for Locomotives and Locomotive Engines § 92.6 Regulatory structure. This section provides...

  9. 5 CFR 880.102 - Regulatory structure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Regulatory structure. 880.102 Section 880.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Regulatory structure. (a) This part contains the following subparts: (1) Subpart A contains...

  10. 5 CFR 880.102 - Regulatory structure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Regulatory structure. 880.102 Section 880.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Regulatory structure. (a) This part contains the following subparts: (1) Subpart A contains...

  11. 40 CFR 94.6 - Regulatory structure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... emissions from in-use marine engines. (b) The engines for which the regulations of this part (i.e., 40 CFR... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Regulatory structure. 94.6 Section 94... for Compression-Ignition Marine Engines § 94.6 Regulatory structure. This section provides an...

  12. 5 CFR 880.102 - Regulatory structure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Regulatory structure. 880.102 Section 880.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Regulatory structure. (a) This part contains the following subparts: (1) Subpart A contains...

  13. 40 CFR 94.6 - Regulatory structure.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... emissions from in-use marine engines. (b) The engines for which the regulations of this part (i.e., 40 CFR... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Regulatory structure. 94.6 Section 94... for Compression-Ignition Marine Engines § 94.6 Regulatory structure. This section provides an...

  14. 5 CFR 847.102 - Regulatory structure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Regulatory structure. 847.102 Section 847.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... INSTRUMENTALITIES General Provisions § 847.102 Regulatory structure. (a)(1) Subpart A of this part...

  15. 40 CFR 94.6 - Regulatory structure.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... emissions from in-use marine engines. (b) The engines for which the regulations of this part (i.e., 40 CFR... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Regulatory structure. 94.6 Section 94... for Compression-Ignition Marine Engines § 94.6 Regulatory structure. This section provides an...

  16. 5 CFR 847.102 - Regulatory structure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Regulatory structure. 847.102 Section 847.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... INSTRUMENTALITIES General Provisions § 847.102 Regulatory structure. (a)(1) Subpart A of this part...

  17. 5 CFR 847.102 - Regulatory structure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Regulatory structure. 847.102 Section 847.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... INSTRUMENTALITIES General Provisions § 847.102 Regulatory structure. (a)(1) Subpart A of this part...

  18. 40 CFR 94.6 - Regulatory structure.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... emissions from in-use marine engines. (b) The engines for which the regulations of this part (i.e., 40 CFR... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Regulatory structure. 94.6 Section 94... for Compression-Ignition Marine Engines § 94.6 Regulatory structure. This section provides an...

  19. 5 CFR 880.102 - Regulatory structure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Regulatory structure. 880.102 Section 880.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Regulatory structure. (a) This part contains the following subparts: (1) Subpart A contains...

  20. 40 CFR 94.6 - Regulatory structure.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in-use marine engines. (b) The engines for which the regulations of this part (i.e., 40 CFR part 94... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Regulatory structure. 94.6 Section 94.6... Compression-Ignition Marine Engines § 94.6 Regulatory structure. This section provides an overview of...

  1. 5 CFR 880.102 - Regulatory structure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Regulatory structure. 880.102 Section 880.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Regulatory structure. (a) This part contains the following subparts: (1) Subpart A contains...

  2. 40 CFR 92.6 - Regulatory structure.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... locomotives and locomotive engines for which the regulations of this part (i.e., 40 CFR part 92) apply are... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Regulatory structure. 92.6 Section 92... Regulations for Locomotives and Locomotive Engines § 92.6 Regulatory structure. This section provides...

  3. 40 CFR 92.6 - Regulatory structure.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... locomotives and locomotive engines for which the regulations of this part (i.e., 40 CFR part 92) apply are... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Regulatory structure. 92.6 Section 92... Regulations for Locomotives and Locomotive Engines § 92.6 Regulatory structure. This section provides...

  4. 40 CFR 92.6 - Regulatory structure.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... locomotives and locomotive engines for which the regulations of this part (i.e., 40 CFR part 92) apply are... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Regulatory structure. 92.6 Section 92... Regulations for Locomotives and Locomotive Engines § 92.6 Regulatory structure. This section provides...

  5. 78 FR 1698 - Semiannual Regulatory Flexibility Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ..., Implementation of Basel III, Minimum Regulatory Capital Ratios, Capital Adequacy, and Transition Provisions..., Capital Adequacy, and Transition Provisions (Docket No. R-1442) Legal Authority: 12 U.S.C. 24; 12 U.S.C... disclosures related to regulatory capital instruments. Timetable: Action Date FR Cite Merged With 7100 AD87...

  6. 5 CFR 340.201 - Regulatory requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 340.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS OTHER THAN FULL-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.201 Regulatory requirements. This subpart contains the regulations of...

  7. 5 CFR 340.201 - Regulatory requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 340.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS OTHER THAN FULL-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.201 Regulatory requirements. This subpart contains the regulations of...

  8. 5 CFR 340.201 - Regulatory requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 340.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS OTHER THAN FULL-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.201 Regulatory requirements. This subpart contains the regulations of...

  9. 47 CFR 101.1309 - Regulatory status.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Regulatory status. 101.1309 Section 101.1309 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Multiple Address Systems General Provisions § 101.1309 Regulatory status. (a) The Commission...

  10. 47 CFR 101.1309 - Regulatory status.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Regulatory status. 101.1309 Section 101.1309 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Multiple Address Systems General Provisions § 101.1309 Regulatory status. (a) The Commission...

  11. 12 CFR 1010.14 - Regulatory exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Regulatory exemptions. 1010.14 Section 1010.14 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION LAND REGISTRATION (REGULATION J) General Requirements § 1010.14 Regulatory exemptions. (a) Eligibility requirements. The following transactions...

  12. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory enforcement....

  13. 31 CFR 132.7 - Regulatory enforcement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Regulatory enforcement. 132.7 Section 132.7 Money and Finance: Treasury Regulations Relating to Money and Finance PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING § 132.7 Regulatory enforcement. The requirements under this part are subject...

  14. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory enforcement....

  15. 47 CFR 69.727 - Regulatory relief.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Regulatory relief. 69.727 Section 69.727 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.727 Regulatory relief. (a) Phase I relief. Upon satisfaction of the Phase...

  16. 47 CFR 69.727 - Regulatory relief.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Regulatory relief. 69.727 Section 69.727 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.727 Regulatory relief. (a) Phase I relief. Upon satisfaction of the Phase...

  17. 47 CFR 69.727 - Regulatory relief.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Regulatory relief. 69.727 Section 69.727 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.727 Regulatory relief. (a) Phase I relief. Upon satisfaction of the Phase...

  18. 47 CFR 69.727 - Regulatory relief.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Regulatory relief. 69.727 Section 69.727 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.727 Regulatory relief. (a) Phase I relief. Upon satisfaction of the Phase...

  19. 47 CFR 69.727 - Regulatory relief.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Regulatory relief. 69.727 Section 69.727 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.727 Regulatory relief. (a) Phase I relief. Upon satisfaction of the Phase...

  20. 77 FR 58025 - Texas Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... Office of Surface Mining Reclamation and Enforcement 30 CFR Part 943 Texas Regulatory Program AGENCY... the Texas regulatory program (Texas program) under the Surface Mining Control and Reclamation Act of 1977 (SMCRA or the Act). Texas proposed revisions to its regulations regarding annual permit...

  1. Federal Trade Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Part XX Federal Trade Commission Semiannual Regulatory Agenda ] FEDERAL TRADE COMMISSION (FTC) FEDERAL TRADE COMMISSION 16 CFR Ch. I Semiannual Regulatory Agenda AGENCY: Federal Trade Commission... published in accordance with section 22(d)(1) of the Federal Trade Commission Act, 15 U.S.C.......

  2. 75 FR 61530 - Issuance of Regulatory Guides

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... Guides 1.84, Rev. 35, ``Design, Fabrication, and Materials Code Case Acceptability, ASME Section III... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555..., Revision 16, on June 2, 2009, 74 FR 26303. On the same date, the NRC published a parallel notice...

  3. Department of Interior Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...: Action Date FR Cite Final Action 04/00/10 Regulatory Flexibility Analysis Required: Yes Agency Contact... idle facilities. Timetable: Action Date FR Cite NPRM 12/00/10 NPRM Comment Period End 02/00/11... Part IX Department of the Interior Semiannual Regulatory Agenda ] DEPARTMENT OF THE INTERIOR...

  4. Genomics in the land of regulatory science.

    PubMed

    Tong, Weida; Ostroff, Stephen; Blais, Burton; Silva, Primal; Dubuc, Martine; Healy, Marion; Slikker, William

    2015-06-01

    Genomics science has played a major role in the generation of new knowledge in the basic research arena, and currently question arises as to its potential to support regulatory processes. However, the integration of genomics in the regulatory decision-making process requires rigorous assessment and would benefit from consensus amongst international partners and research communities. To that end, the Global Coalition for Regulatory Science Research (GCRSR) hosted the fourth Global Summit on Regulatory Science (GSRS2014) to discuss the role of genomics in regulatory decision making, with a specific emphasis on applications in food safety and medical product development. Challenges and issues were discussed in the context of developing an international consensus for objective criteria in the analysis, interpretation and reporting of genomics data with an emphasis on transparency, traceability and "fitness for purpose" for the intended application. It was recognized that there is a need for a global path in the establishment of a regulatory bioinformatics framework for the development of transparent, reliable, reproducible and auditable processes in the management of food and medical product safety risks. It was also recognized that training is an important mechanism in achieving internationally consistent outcomes. GSRS2014 provided an effective venue for regulators andresearchers to meet, discuss common issues, and develop collaborations to address the challenges posed by the application of genomics to regulatory science, with the ultimate goal of wisely integrating novel technical innovations into regulatory decision-making.

  5. Environmental regulatory update table, November 1987

    SciTech Connect

    Langston, M.E.; Sharples, F.E.; Tucker, C.S.

    1987-11-01

    This report provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  6. Environmental regulatory update table, September 1987

    SciTech Connect

    Langston, M.E.; Sharples, F.E.; Tucker, C.S.

    1987-10-01

    This report provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  7. Environmental Regulatory Update Table, May 1987

    SciTech Connect

    Brown, K.J.; Tucker, C.S.; Reed, R.M.

    1987-06-01

    Information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management oversight is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  8. Meditation and its regulatory role on sleep.

    PubMed

    Nagendra, Ravindra P; Maruthai, Nirmala; Kutty, Bindu M

    2012-01-01

    Intense meditation practices help to achieve a harmony between body and mind. Meditation practices influence brain functions, induce various intrinsic neural plasticity events, modulate autonomic, metabolic, endocrine, and immune functions and thus mediate global regulatory changes in various behavioral states including sleep. This brief review focuses on the effect of meditation as a self regulatory phenomenon on sleep.

  9. 78 FR 44315 - Spring 2013 Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Agenda and the E-Agenda? G. How can you find out about rulemakings that start up after the Regulatory... requirements contained in numerous executive orders: 12866, ``Regulatory Planning and Review'' (58 FR 51735...'' (76 FR 3821, Jan. 21, 2011); 12898, ``Environmental Justice'' (59 FR 7629, Feb. 16, 1994);...

  10. 78 FR 1708 - Regulatory Flexibility Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... section 4(6) of the Securities Act. Timetable: Action Date FR Cite NPRM 12/00/12 Regulatory Flexibility... Expansion) of the JOBS Act. Timetable: Action Date FR Cite NPRM 01/00/13 Regulatory Flexibility Analysis... on existing exemptions under the Securities Act. Timetable: Action Date FR Cite Interim Final Rule...

  11. [Regulatory B cells in human autoimmune diseases].

    PubMed

    Miyagaki, Tomomitsu

    2015-01-01

    B cells have been generally considered to be positive regulators of immune responses because of their ability to produce antigen-specific antibodies and to activate T cells through antigen presentation. Impairment of B cell development and function may cause autoimmune diseases. Recently, specific B cell subsets that can negatively regulate immune responses have been described in mouse models of a wide variety of autoimmune diseases. The concept of those B cells, termed regulatory B cells, is now recognized as important in the murine immune system. Among several regulatory B cell subsets, IL-10-producing regulatory B cells are the most widely investigated. On the basis of discoveries from studies of such mice, human regulatory B cells that produce IL-10 in most cases are becoming an active area of research. There have been emerging data suggesting the importance of human regulatory B cells in various diseases. Revealing the immune regulation mechanisms of human regulatory B cells in human autoimmune diseases could lead to the development of novel B cell targeted therapies. This review highlights the current knowledge on regulatory B cells, mainly IL-10-producing regulatory B cells, in clinical research using human samples. PMID:26725860

  12. Weight of evidence: regulatory toxicology in Canada

    SciTech Connect

    Somers, E.

    1986-12-01

    The legislative application of regulatory toxicology in Canada is reviewed, together with the sources of experimental evidence used for action. Examples are given of the critical toxicological information that led to a regulatory decision. Risk numbers have only been used to a limited extent in Canada. Some possibilities for future research are offered.

  13. 76 FR 40208 - Regulatory Flexibility Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... Date FR Cite NPRM 03/00/12 Regulatory Flexibility Analysis Required: Yes. Agency Contact: Sean Harrison... Rule 506 of Regulation D. Timetable: Action Date FR Cite NPRM 06/01/11 76 FR 31518 NPRM Comment Period... by registrants. Timetable: Action Date FR Cite NPRM 03/00/12 Regulatory Flexibility Analysis...

  14. 76 FR 40050 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... July 7, 2011 Part VII Department of Energy Semiannual Regulatory Agenda #0;#0;Federal Register / Vol. 76 , No. 130 / Thursday, July 7, 2011 / Unified Agenda#0;#0; ] DEPARTMENT OF ENERGY 10 CFR Chs. II, III, and X 48 CFR Ch. 9 Semiannual Regulatory Agenda AGENCY: Department of Energy. ACTION: Notice...

  15. 78 FR 1570 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... January 8, 2013 Part VII Department of Energy Semiannual Regulatory Agenda #0;#0;Federal Register / Vol. 78 , No. 5 / Tuesday, January 8, 2013 / Unified Agenda#0;#0; ] DEPARTMENT OF ENERGY 10 CFR Chs. II, III, and X 48 CFR Ch. 9 Semiannual Regulatory Agenda AGENCY: Department of Energy. ACTION: Notice...

  16. Regulatory Reform: Low Risk, High Promise.

    ERIC Educational Resources Information Center

    Tanenbaum, Morris

    The press of telecommunication technologies and their progeny have undermined the natural monopoly basis for long distance telecommunications and customer premise products, forced open regulatory doors, toppled barriers to market entry, and led to the reshaping of regulatory philosophy as regulators have seen new, wider horizons for the industry.…

  17. Department of Transportation Agency Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... accordance with Executive Order 12866 ``Regulatory Planning and Review'' (58 FR 51735; October 4, 1993) and the Department's Regulatory Policies and Procedures (44 FR 11034; February 26, 1979), the Department... last agenda was published in the Federal Register on April 26, 2010 (75 FR 21840). The next one...

  18. 76 FR 33181 - Regulatory Review Schedule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... processes. (76 FR 18457, April 4, 2011). The Commission's regulatory review process establishes a detailed... National Indian Gaming Commission 25 CFR Chapter III Regulatory Review Schedule AGENCY: National Indian... Notice of Consultation advising the public that the NIGC was conducting a comprehensive review of all...

  19. 49 CFR 355.21 - Regulatory review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Regulatory review. 355.21 Section 355.21... AND REGULATIONS AFFECTING INTERSTATE MOTOR CARRIER OPERATIONS Requirements § 355.21 Regulatory review... review are provided in the appendix to this part. (b) Responsibility. The State agency designated as...

  20. 76 FR 54408 - Regulatory Review Schedule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    .... (76 FR 18457, April 4, 2011). The Commission's regulatory review process established a tribal... National Indian Gaming Commission 25 CFR Chapter III Regulatory Review Schedule AGENCY: National Indian..., 1441 L Street, NW., Suite 9100, Washington, DC 20005. Telephone: 202-632-7003; e-mail:...

  1. 77 FR 10351 - Regulatory Review Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... plan and requested comments on the plan. 76 FR 59066 (September 23, 2011). FHFA received no comments... XII Regulatory Review Plan AGENCY: Federal Housing Finance Agency. ACTION: Notice of final regulatory review plan. SUMMARY: The Federal Housing Finance Agency (FHFA) is issuing a notice of the final...

  2. 76 FR 26967 - Regulatory Review Schedule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... National Indian Gaming Commission 25 CFR Chapter III Regulatory Review Schedule AGENCY: National Indian... advising the public that the NIGC was conducting a comprehensive review of its regulations and requesting public comment on the process for conducting the regulatory review. On April 4, 2011, after holding...

  3. 49 CFR 355.21 - Regulatory review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Regulatory review. 355.21 Section 355.21... AND REGULATIONS AFFECTING INTERSTATE MOTOR CARRIER OPERATIONS Requirements § 355.21 Regulatory review... review are provided in the appendix to this part. (b) Responsibility. The State agency designated as...

  4. 75 FR 79925 - Semiannual Regulatory Flexibility Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... FR Cite Board Issued Final Rule on 02/22/10 75 FR 7658 Regulatory Flexibility Analysis Required: Yes... FR 37526 Regulatory Flexibility Analysis Required: Yes Agency Contact: Amy Henderson, Senior Attorney... similar to the proposed rule. Timetable: Action Date FR Cite Board Requested Comment 08/26/09 74 FR...

  5. Water resources of Carbon County, Wyoming

    USGS Publications Warehouse

    Bartos, Timothy T.; Hallberg, Laura L.; Mason, Jon P.; Norris, Jodi R.; Miller, Kirk A.

    2006-01-01

    Carbon County is located in the south-central part of Wyoming and is the third largest county in the State. A study to describe the physical and chemical characteristics of surface-water and ground-water resources in Carbon County was conducted by the U.S. Geological Survey in cooperation with the Wyoming State Engineer's Office. Evaluations of streamflow and stream-water quality were limited to analyses of historical data and descriptions of previous investigations. Surface-water data were not collected as part of the study. Forty-five ground-water-quality samples were collected as part of the study and the results from an additional 618 historical ground-water-quality samples were reviewed. Available hydrogeologic characteristics for various aquifers in hydrogeologic units throughout the county also are described. Flow characteristics of streams in Carbon County vary substantially depending on regional and local basin char-acteristics and anthropogenic factors. Precipitation in the county is variable with high mountainous areas receiving several times the annual precipitation of basin lowland areas. For this reason, streams with headwaters in mountainous areas generally are perennial, whereas most streams in the county with headwaters in basin lowland areas are ephemeral, flowing only as a result of regional or local rainfall or snowmelt runoff. Flow characteristics of most perennial streams are altered substantially by diversions and regulation. Water-quality characteristics of selected streams in and near Carbon County during water years 1966 through 1986 varied. Concentrations of dissolved constituents and suspended sediment were smallest at sites on streams with headwaters in mountainous areas because of resistant geologic units, large diluting streamflows, and increased vegetative cover compared to sites on streams with headwaters in basin lowlands. Both water-table and artesian conditions occur in aquifers within the county. Shallow ground water is

  6. Nye County Nevada Perspectives on the State of the Yucca Mountain Project - 12388

    SciTech Connect

    Lacy, Darrell; Voegele, Michael; Jaszczak, Casmier

    2012-07-01

    Responding to the Department of Energy decision to try to withdraw the Yucca Mountain license application and the Administration actions to close down the Yucca Mountain project, Nye County undertook a number of activities to articulate its support for continuing the Yucca Mountain project. The activities included responding to inquiries from federal agencies, including investigations undertaken by the Government Accountability Office addressing other potential uses for the Yucca Mountain site, responding to a Draft Environmental Impact Statement on the possible use of Yucca Mountain for disposal of Greater than Class C wastes, testifying in hearings, and interacting with the President's Blue Ribbon Commission on America's Nuclear Future. The paper summarizes Nye County's position on the Yucca Mountain repository, Nye County's perspectives on the various activities that were developed and considered by the Government Accountability Office, Nye County's concerns with the use of the Nevada National Security Site for Disposal of Greater than Class C Low-Level Radioactive Wastes, testimony of Nye County officials expressing local community support for the Yucca Mountain project, and Nye County's perspectives on recommendations provided by the Blue Ribbon Commission to move the nation's high-level radioactive waste disposal programs forward without consideration of the role Yucca Mountain could have served in those recommendations. Nye County believes that every effort should be made to, at a minimum, fund the Nuclear Regulatory Commission to complete the license application review. Then, if Congress does decide to change the Nuclear Waste Policy Act, there will be valuable information available to support new policy development. This administration contends that Congressional language associated with the FY2010 and FY2011 appropriations and authorization process is sufficient evidence of its intent to terminate the Yucca Mountain repository program. The appropriation

  7. Mediation: Sanity in the regulatory process

    SciTech Connect

    Cohen, D.S.

    1993-01-15

    The regulatory process is in need of change. The adversarial model used by most regulatory agencies is an inefficient, expensive, and conflict-producing procedure. Ill-adapted to resolving issues of great public policy concern, regulation calls out for non-adversarial alternative processes to address the resolution of public policy disputes between the players in the regulatory process. The adversarial model of regulation mimics traditional courtroom procedures. It is designed to determine issues of fact, not issues of public policy with legal maneuvering used to shroud the development of facts. Conflict maintenance and not conflict resolution has become the hallmark of the adversarial process in the regulatory arena. Unlike the courtroom process which provides a certain finality to conflicts, the adversarial process in the regulatory process is perpetual.

  8. The Bridge of Mandolin County

    NASA Astrophysics Data System (ADS)

    Lantz, Juliette M.; Feindt, Jenny E.; Lewellyn, Eric P. B.; Walczak, Mary M.

    1999-12-01

    The Bridge of Mandolin County is a case designed to teach the general chemistry principles of molar mass, ions and aqueous reactions, solubility rules, and inorganic nomenclature. Through the instructor-facilitated class discussion, students consider the options before the Mandolin Town Council regarding deicing the newly constructed bridge connecting Mandolin with a large nearby city. The students must decipher contradictory claims made on behalf of sodium chloride, the traditional deicer, and calcium magnesium acetate, a new environmentally friendly deicer, to arrive at the most cost-effective and environmentally appropriate deicing product. As they work through the analysis they raise questions that can be addressed in a laboratory setting. Four optional role-playing experiments are included, which can be used by the students to gather information helpful to resolution of the case. The case is intended to be used over two class periods, with a laboratory period in between, though suggestions for other models are provided. Laboratory procedures include an EDTA titration for Ca2+ and Mg2+, a gravimetric analysis, a qualitative examination of ions and solubility, an introduction to freezing point depression and measurement, and an experimental design activity. This case can also successfully be used without alteration in non-majors chemistry or environmental chemistry courses, or upper-level analytical or environmental chemistry courses.

  9. Constraints of Implementing Free Secondary Education in Mandera West Sub-County, Mandera County, Kenya

    ERIC Educational Resources Information Center

    Adan, Mohammed Abdi; Orodho, John Aluko

    2015-01-01

    This study sought to find out the constraints of implementing free secondary education (FSE) in secondary schools in Mandera West Sub-County, Mandera County, Kenya. The study is based on the theory of constraints as the researcher examines the factors constraining the achievement of FSE objectives. The study used the survey design. The main…

  10. Coping with Resource Management Challenges in Mumias Sub-County, Kakamega County, Kenya

    ERIC Educational Resources Information Center

    Anyango, Onginjo Rose; Orodho, John Aluko

    2016-01-01

    The gist of the study was to examine the main coping strategies used to manage resources in public secondary schools in Mumias Sub-County, Kakamega County, Kenya. The study was premised on Hunts (2007) theory on project management. A descriptive survey design was adopted. A combination of purposive and simple random sampling techniques were used…

  11. 75 FR 31463 - Comal County Regional Habitat Conservation Plan, Comal County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Federal Register on October 16, 2008 (73 FR 61433). A public scoping meeting was held on December 4, 2008... Fish and Wildlife Service Comal County Regional Habitat Conservation Plan, Comal County, TX AGENCY... statement, draft habitat conservation plan, and permit application; announcement of a public...

  12. How Are Kentucky's Children Stacking Up? A County by County Analysis.

    ERIC Educational Resources Information Center

    Chandler, Betsy

    In a county by county analysis, this report assesses the quality of life for Kentucky's children. Researchers developed a child quotient (CQ) based on 18 indicators: per capita income, children in poverty, women receiving inadequate prenatal care, infant deaths, teens giving birth, substandard dwellings, children in foster care, per-pupil…

  13. The Need for a Branch Campus of Ocean County College in Southern Ocean County.

    ERIC Educational Resources Information Center

    Parrish, Richard M.; Harris, David W.

    A study was conducted to determine the feasibility of establishing a branch campus of Ocean County College (OCC) in southern Ocean County, New Jersey. Specific variables examined during the study included demographic characteristics; transportation systems, in terms of both public access and roadway networks; land usage; the history of education…

  14. 76 FR 4254 - Irish Potatoes Grown in Certain Designated Counties in Idaho, and Malheur County, Oregon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Designated Counties in Idaho, and Malheur County, Oregon; Continuance Referendum AGENCY: Agricultural Marketing Service, USDA. ACTION: Referendum order. SUMMARY: This document directs that a referendum be... handling of Irish potatoes grown in the production area. DATES: The referendum will be conducted from...

  15. Beginnings of geothermal impact on county population and leadership, Imperial County, California

    SciTech Connect

    Pick, J.B.; Butler, E.W.

    1980-09-01

    A major geothermal energy development scenario is about to begin in Imperial County. Initial energy-socioeconomic interactions in the areas of population and county leadership structure are discussed. These include immigration of energy company workers, a sewage plant dispute, conflict over union affiliation of geothermal laborers, and a transmission corridor routing dispute.

  16. Youth Representation on County Government Committees: Youth in Governance in Kenosha County, Wisconsin

    ERIC Educational Resources Information Center

    Calvert, Matthew; de Montmollin, John; Winnett, Tedi

    2015-01-01

    The Kenosha County Youth in Governance program was created to build leadership skills and civic engagement opportunities for high school-aged students by placing two youth representatives on each of the Kenosha County Board of Supervisors standing committees. In reviewing data from 3 years of youth participants, the program was effective in…

  17. [Agreement between the Cumberland County College Board of Trustees and the Cumberland County College Faculty Association.

    ERIC Educational Resources Information Center

    Cumberland County Coll., Vineland, NJ.

    This document presents the agreement between the Cumberland County College Board of Trustees and the Cumberland County College Faculty Association. Articles of the agreement cover recognition; negotiation procedure; association rights and responsibilities; conditions of employment; faculty benefits; salaries; compensation for graduate work;…

  18. Citrus County Schools Copyright Guidelines Recommended by the Citrus County Association of School Media Specialists.

    ERIC Educational Resources Information Center

    Citrus County School District, Inverness, FL.

    This document contains copyright guidelines determined appropriate for the Citrus County School System (Florida) by the Citrus County Association of School Media Specialists in May, 1992. These guidelines are based on interpretation and understanding of current copyright law as applied to education and implemented in school districts in the United…

  19. Spatial analysis of ozone in Atlanta: Regulatory and epidemiologic implications

    SciTech Connect

    Butler, A.J.; Mulholland, J.A.; Wilkinson, J.G.; Russell, A.G.; Tolbert, P.E.

    1998-12-31

    Relationships between ambient levels of selected air pollutants and pediatric asthma exacerbation in Atlanta were studied retrospectively. As a part of this study, spatial distributions of ambient ozone concentrations in the twenty-county Atlanta metropolitan area during the summers of 1993, 1994 and 1995 were estimated and assessed. A universal kriging procedure was used for spatial interpolation of aerometric monitoring station data. In this paper, the spatial distributions of ozone are described, and regulatory and epidemiologic implications are discussed. For the study period, the Atlanta ozone nonattainment area based on the one-hour, exceedance-based standard of 0.12 ppm is estimated to expand from 56 percent of the Atlanta MSA by area and 71 percent by population to 88 percent by area and 96 percent by population under the new eight-hour, concentration-based standard of 0.08 ppm. Regarding asthma exacerbation, a 4 percent increase in pediatric asthma emergency room presentation rate per 20 ppb increase in ambient ozone concentration was observed (p-value = 0.001). Ambient ozone level represents a general indicator of air quality due to its correlation with other pollutants. The use of spatially-resolved ozone estimates in the epidemiologic analysis demonstrates the need to control confounding by demographic covariates.

  20. Boolean Modelingof Genetic Regulatory Networks

    NASA Astrophysics Data System (ADS)

    Albert, Réka

    Biological systems form complex networks of interaction on several scales, ranging from the molecular to the ecosystem level. On the subcellular scale, interaction between genes and gene products (mRNAs, proteins) forms the basis of essential processes like signal transduction, cell metabolism or embryonic development. Recent experimental advances helped uncover the qualitative structure of many gene control networks, creating a surge of interest in the quantitative description of gene regulation. We give a brief description of the main frameworks and methods used in modeling gene regulatory networks, then focus on a recent model of the segment polarity genes of the fruit fly Drosophila melanogaster. The basis of this model is the known interactions between the products of the segment polarity genes, and the network topology these interactions form. The interactions between mRNAs and proteins are described as logical (Boolean) functions. The success in reproducing both wild type and mutant gene expression patterns suggests that the kinetic details of the interactions are not essential as long as the network of interactions is unperturbed. The model predicts the gene patterns for cases that were not yet studied experimentally, and implies a remarkable robustness toward changes in internal parameters, initial conditions and even some mutations.

  1. Evolving Robust Gene Regulatory Networks

    PubMed Central

    Noman, Nasimul; Monjo, Taku; Moscato, Pablo; Iba, Hitoshi

    2015-01-01

    Design and implementation of robust network modules is essential for construction of complex biological systems through hierarchical assembly of ‘parts’ and ‘devices’. The robustness of gene regulatory networks (GRNs) is ascribed chiefly to the underlying topology. The automatic designing capability of GRN topology that can exhibit robust behavior can dramatically change the current practice in synthetic biology. A recent study shows that Darwinian evolution can gradually develop higher topological robustness. Subsequently, this work presents an evolutionary algorithm that simulates natural evolution in silico, for identifying network topologies that are robust to perturbations. We present a Monte Carlo based method for quantifying topological robustness and designed a fitness approximation approach for efficient calculation of topological robustness which is computationally very intensive. The proposed framework was verified using two classic GRN behaviors: oscillation and bistability, although the framework is generalized for evolving other types of responses. The algorithm identified robust GRN architectures which were verified using different analysis and comparison. Analysis of the results also shed light on the relationship among robustness, cooperativity and complexity. This study also shows that nature has already evolved very robust architectures for its crucial systems; hence simulation of this natural process can be very valuable for designing robust biological systems. PMID:25616055

  2. Orphan drugs: the regulatory environment.

    PubMed

    Franco, Pedro

    2013-02-01

    The definition of a rare disease is not universal and depends on the legislation and policies adopted by each region or country. The main objective of this article is to describe and discuss the legal framework and the regulatory environment of orphan drugs worldwide. Some reflections and discussions on the need for specific orphan drug legislation or policies are described at length. Furthermore, some aspects of the history of each region in respect of the orphan drug legislation evolution are outlined. This article describes and compares the orphan drug legislation or policies of the following countries or regions: United Sates of America (US), European Union (EU), Japan, Australia, Singapore, Taiwan and Canada. The incentives described in the orphan drug legislations or policies, the criteria for designation of orphan status and the authorisation process of an orphan drug are also described and compared. The legislations and policies are to some extent similar but not the same. It is important to understand the main differences among all available legislative systems to improve the international collaboration in the field of orphan drugs and rare diseases.

  3. Estimated land-surface subsidence in Harris County, Texas, 1915-17 to 2001

    USGS Publications Warehouse

    Kasmarek, Mark C.; Gabrysch, Robert K.; Johnson, Michaela R.

    2009-01-01

    Land-surface subsidence, or land subsidence, in Harris County, Texas, which encompasses much of the Houston area, has been occurring for decades. Land subsidence has increased the frequency and extent of flooding, damaged buildings and transportation infrastructure, and caused adverse environmental effects. The primary cause of land subsidence in the Houston area is withdrawal of groundwater, although extraction of oil and gas also has contributed. Throughout most of the 20th century, groundwater was the primary source of municipal, agricultural, and industrial water supply for Harris County. Currently (2009) a transition to surface water as the primary source of supply, guided by a groundwater regulatory plan developed by the Harris-Galveston Subsidence District (2001), is in effect. The aquifers in Harris County contain an abundant amount of potable groundwater, but they also contain layers of clay. Groundwater withdrawals caused compaction of the clay layers, which in turn resulted in the widespread, substantial land-surface subsidence that has occurred in the Houston area.

  4. Geology of Griggs and Steele Counties

    USGS Publications Warehouse

    Bluemle, John P.

    1975-01-01

    Griggs and Steele Counties, located at the eastern edge of the Williston basin, are underlain by 400 to 2,600 feet of Paleozoic and Mesozoic rocks that dip gently to the west. The Cretaceous Greenhorn, Carlile, Niobrara, and Pierre Formations lie directly beneath the glacial drift, and shale of the Pierre Formation is exposed in several places along the Sheyenne River. The Pleistocene Coleharbor Formation, which covers most of the area, consists mainly of glacial, fluvial, and lake sediment. The Coleharbor Formation averages 200 to 300 feet thick, but it is as much as 550 feet thick in some of the buried valleys. The Holocene Walsh Formation occurs in parts of the area, chiefly sloughs and river bottomland. It consists mainly of alluvial and eolian sediment. Griggs County and the western two-thirds of Steele County are part of the Drift Prairie, which is characterized by flat to gently rolling topography that is rugged in areas of end moraines and intense ice thrusting, subdued on the ground moraine and outwash plains. Associated with these major landforms are numerous washboard moraines, drumlins, eskers, kames, meltwater trenches, and water-washed areas. The eastern third of Steele County is a nearly flat area covered by lake deposits of the glacial Lake Agassiz. As the Late Wisconsinan glacier in eastern North Dakota thinned and receded eastward, it was increasingly affected by the topography over which it was flowing. This resulted in lobation of the glacier. Locally intense areas of thrusting developed within the lobate glacier, and large blocks of subglacial material were moved short distances. Large areas of Griggs County were washed by water flowing from the glacier, and in some areas gravel and sand were deposited. Continued withdrawal of the glacier resulted in ponding of melt water in parts of the two counties. These and other ponds tended to coalesce at lower and lower elevations, eventually forming Lake Agassiz, which flooded part of eastern Steele

  5. Ground water in Creek County, Oklahoma

    USGS Publications Warehouse

    Cady, Richard Carlysle

    1937-01-01

    Creek County has been designated as a problem area by the Land Use Planning Section of the Resettlement Administration. Some of the earliest oil fields to brought into production were situated in and near this county, and new fields have been opened from time to time during the ensuing years. The production of the newer fields, however, has not kept pace with the exhaustion of the older fields, and the county now presents an excellent picture of the problems involved in adjusting a population to lands that are nearly depleted of their mineral wealth. Values of land have been greatly depressed; tax collection is far in arrears; tenancy is widespread; and in addition more people will apparently be forced to depend on the income from agriculture than the land seems capable of supporting. The county as a whole is at best indifferently suitable for general farming. The Land Use planning Section proposes to study the present and seemingly immanent maladjustments of population to the resources of the land, and make recommendations for their correction. The writer was detailed to the Land Use Planning Section of Region VIII for the purposes of making studies of ground water problems in the region. In Creek County two investigations were made. In September, 1936, the writer spent about ten days investigating the availability of ground water for the irrigation of garden crops during drouths. If it proved feasible to do this generally throughout the county, the Land Use Planning Section might be able to encourage this practice. The second investigation made by the writer was in regard to the extent to which ground water supplies have been damaged by oil well brines. He was in county for four days late in January 1937, and again in March, 1937. During part of the second field trip he was accompanied by R.M. Dixon, sanitary engineer of the Water Utilization Unit of the Resettlement Administration. (available as photostat copy only)

  6. Regulatory analysis technical evaluation handbook. Final report

    SciTech Connect

    1997-01-01

    The purpose of this Handbook is to provide guidance to the regulatory analyst to promote preparation of quality regulatory analysis documents and to implement the policies of the Regulatory Analysis Guidelines of the US Nuclear Regulatory Commission (NUREG/BR-0058 Rev. 2). This Handbook expands upon policy concepts included in the NRC Guidelines and translates the six steps in preparing regulatory analyses into implementable methodologies for the analyst. It provides standardized methods of preparation and presentation of regulatory analyses, with the inclusion of input that will satisfy all backfit requirements and requirements of NRC`s Committee to Review Generic Requirements. Information on the objectives of the safety goal evaluation process and potential data sources for preparing a safety goal evaluation is also included. Consistent application of the methods provided here will result in more directly comparable analyses, thus aiding decision-makers in evaluating and comparing various regulatory actions. The handbook is being issued in loose-leaf format to facilitate revisions. NRC intends to periodically revise the handbook as new and improved guidance, data, and methods become available.

  7. Regulatory bioinformatics for food and drug safety.

    PubMed

    Healy, Marion J; Tong, Weida; Ostroff, Stephen; Eichler, Hans-Georg; Patak, Alex; Neuspiel, Margaret; Deluyker, Hubert; Slikker, William

    2016-10-01

    "Regulatory Bioinformatics" strives to develop and implement a standardized and transparent bioinformatic framework to support the implementation of existing and emerging technologies in regulatory decision-making. It has great potential to improve public health through the development and use of clinically important medical products and tools to manage the safety of the food supply. However, the application of regulatory bioinformatics also poses new challenges and requires new knowledge and skill sets. In the latest Global Coalition on Regulatory Science Research (GCRSR) governed conference, Global Summit on Regulatory Science (GSRS2015), regulatory bioinformatics principles were presented with respect to global trends, initiatives and case studies. The discussion revealed that datasets, analytical tools, skills and expertise are rapidly developing, in many cases via large international collaborative consortia. It also revealed that significant research is still required to realize the potential applications of regulatory bioinformatics. While there is significant excitement in the possibilities offered by precision medicine to enhance treatments of serious and/or complex diseases, there is a clear need for further development of mechanisms to securely store, curate and share data, integrate databases, and standardized quality control and data analysis procedures. A greater understanding of the biological significance of the data is also required to fully exploit vast datasets that are becoming available. The application of bioinformatics in the microbiological risk analysis paradigm is delivering clear benefits both for the investigation of food borne pathogens and for decision making on clinically important treatments. It is recognized that regulatory bioinformatics will have many beneficial applications by ensuring high quality data, validated tools and standardized processes, which will help inform the regulatory science community of the requirements

  8. Regulatory bioinformatics for food and drug safety.

    PubMed

    Healy, Marion J; Tong, Weida; Ostroff, Stephen; Eichler, Hans-Georg; Patak, Alex; Neuspiel, Margaret; Deluyker, Hubert; Slikker, William

    2016-10-01

    "Regulatory Bioinformatics" strives to develop and implement a standardized and transparent bioinformatic framework to support the implementation of existing and emerging technologies in regulatory decision-making. It has great potential to improve public health through the development and use of clinically important medical products and tools to manage the safety of the food supply. However, the application of regulatory bioinformatics also poses new challenges and requires new knowledge and skill sets. In the latest Global Coalition on Regulatory Science Research (GCRSR) governed conference, Global Summit on Regulatory Science (GSRS2015), regulatory bioinformatics principles were presented with respect to global trends, initiatives and case studies. The discussion revealed that datasets, analytical tools, skills and expertise are rapidly developing, in many cases via large international collaborative consortia. It also revealed that significant research is still required to realize the potential applications of regulatory bioinformatics. While there is significant excitement in the possibilities offered by precision medicine to enhance treatments of serious and/or complex diseases, there is a clear need for further development of mechanisms to securely store, curate and share data, integrate databases, and standardized quality control and data analysis procedures. A greater understanding of the biological significance of the data is also required to fully exploit vast datasets that are becoming available. The application of bioinformatics in the microbiological risk analysis paradigm is delivering clear benefits both for the investigation of food borne pathogens and for decision making on clinically important treatments. It is recognized that regulatory bioinformatics will have many beneficial applications by ensuring high quality data, validated tools and standardized processes, which will help inform the regulatory science community of the requirements

  9. 75 FR 62436 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Coatings Applied to Nuclear Power Plants.'' FOR FURTHER INFORMATION CONTACT: Bruce P. Lin, Division...

  10. 76 FR 31382 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Surveys and Monitoring.'' FOR FURTHER INFORMATION CONTACT: Harriet Karagiannis, U.S. Nuclear...

  11. Water resources of King County, Washington

    USGS Publications Warehouse

    Richardson, Donald; Bingham, J.W.; Madison, R.J.; Williams, R.

    1968-01-01

    Although the total supply of water in King County is large, water problems are inevitable because of the large and rapidly expanding population. The county contains a third of the 3 million people in Washington, most of the population being concentrated in the Seattle metropolitan area. King County includes parts of two major physiographic features: the western area is part of the Puget Sound Lowland, and the eastern area is part of the Cascade Range. In these two areas, the terrain, weather, and natural resources (including water) contrast markedly. Average annual precipitation in the county is about 80 inches, ranging from about 30 inches near Puget Sound to more than 150 inches in parts of the Cascades. Annual evapotranspiration is estimated to range from 15 to 24 inches. Average annual runoff ranges from about 15 inches in the lowlands to more than 100 inches in the mountains. Most of the streamflow is in the major basins of the county--the Green-Duwamish, Lake Washington, and Snoqualmie basins. The largest of these is the Snoqualmie River basin (693 square miles), where average annual runoff during the period 1931-60 was about 79 inches. During the same period, annual runoff in the Lake Washington basin ( 607 square miles) averaged about 32 inches, and in the Green-Duwamish River basin (483 square miles), about 46 inches. Seasonal runoff is generally characterized by several high-flow periods in the winter, medium flows in the spring, and sustained low flows in the summer and fall. When floods occur in the county they come almost exclusively between October and March. The threat of flood damage is greatest on the flood plaits of the larger rivers, but in the Green-Duwamish Valley the threat was greatly reduced with the completion of Howard A. Hanson Dam in 1962. In the Snoqualmie River basin, where no such dam exists, the potential damage from a major flood increases each year as additional land is developed in the Snoqualmie Valley. 0nly moderate amounts of

  12. Regulatory T cells: balancing protection versus pathology.

    PubMed

    Rakebrandt, Nikolas; Littringer, Katharina; Joller, Nicole

    2016-01-01

    Foxp3+ regulatory T cells (Tregs) maintain immune tolerance, prevent autoimmunity and modulate immune responses during infection and cancer. Recent studies have revealed considerable heterogeneity and plasticity within the Treg compartment, depending on the immunological context, which may result in Tregs losing their suppressive function in inflammatory environments. We review how dysfunctional Tregs contribute to disease pathogenesis in inflammatory conditions and how inappropriate regulatory responses may hamper protective immunity in the context of infection and cancer. We also discuss how Tregs might be targeted therapeutically to re-establish a proper balance between regulatory and effector responses in autoimmunity, infections, and cancer. PMID:27497235

  13. REGULATORY T CELLS AND VASECTOMY

    PubMed Central

    Rival, Claudia; Wheeler, Karen; Jeffrey, Sarah; Qiao, Hui; Luu, Brian; Tewalt, Eric F; Engelhard, Victor H; Tardif, Stephen; Hardy, Daniel; del Rio, Roxana; Teuscher, Cory; Tung, Kenneth

    2013-01-01

    CD4+CD25+ regulatory T cells (Tregs) strongly influence the early and late autoimmune responses to meiotic germ cell antigens (MGCA) and the gonadal immunopathology in vasectomized mice. This is supported by the published and recently acquired information presented here. Within 24 hours of unilateral vasectomy (uni-vx) the ipsilateral epididymis undergoes epithelial cell apoptosis followed by necrosis, severe inflammation, and granuloma formation. Unexpectedly, vasectomy alone induced MGCA-specific tolerance. In contrast, uni-vx plus simultaneous Treg depletion resulted in MGCA-specific autoimmune response and bilateral autoimmune orchitis. Both tolerance and autoimmunity were strictly linked to the early epididymal injury. We now discovered that testicular autoimmunity in uni-vx mice did not occur when Treg depletion was delayed by one week. Remarkably, this delayed Treg depletion also prevented tolerance induction. Therefore, tolerance depends on a rapid de novo Treg response to MGCA exposed after vasectomy. Moreover, tolerance was blunted in mice genetically deficient in PD-1 ligand, suggesting the involvement of induced Treg. We conclude that pre-existing natural Treg prevents post-vasectomy autoimmunity, whereas vasectomy-induced Treg maintains post-vasectomy tolerance. We further discovered that vasectomized mice were still resistant to autoimmune orchitis induction for at least 12–16 months; thus, tolerance is long-lasting. Although significant sperm autoantibodies of low titers became detectable in uni-vx mice at seven months, the antibody titers fluctuated over time, suggesting a dynamic “balance” between the autoimmune and tolerance states. Finally, we observed severe epididymal fibrosis and hypo-spermatogenesis at 12 months after uni-vx: findings of highly critical clinical significance. PMID:24080233

  14. Dutchess County Resource Recovery Task Force report: Dutchess County Pyrolysis Program

    SciTech Connect

    1980-07-01

    Dutchess County initiated development of a long-range master plan for Solid Waste Management in 1971. The plan included development of a resource recovery facility to service the municipalities in the County population center. Based on early recommendations, a pyrolysis facility employing Purox technology was to be implemented. A feasibility study, paid for by County funds was completed in 1975. The study provided siting recommendations, estimation of available waste, and preliminary facility design. Because of various considerations, the project was not developed. Under the Department of Energy grant, the County reassessed the feasibility of a resource recovery facility, with emphasis on confirming previous conclusions supporting the Purox technology, waste availability, energy recovery and sale and siting of the plant. The conclusions reached in the new study were: a resource recovery facility is feasible for the County; sufficient waste for such a facility is available and subject to control; While Purox technology was feasible it is not the most appropriate available technoloy for the County; that mass burning with steam recovery is the most appropriate technology; and that resource recovery while presently more expensive than landfilling, represents the only cost effective, energy efficient, and environmentally sound way to handle the solid waste problem in the County.

  15. Selenium status of Utah County residents

    SciTech Connect

    Bown, J.W.; Christensen, M.J.

    1986-03-01

    Counties of low and high soil selenium (Se) content appear to be in close proximity in the state of Utah. The Se status of Utah County residents was evaluated by measurement of plasma Se concentration, and plasma, platelet, and erythrocyte (RBC) Se-glutathione peroxidase (Se-GSH-Px) activity. A Random Digit Dialing procedure was employed to stratify subjects according to sex and annual income (< $10,000, $10-20,000, > $20,000) in a 2 x 3 factorial design, 7 subjects per cell. There were no significant differences due to sex or income. These results suggest (1) the Se status of Utah County residents is similar to that reported for residents of other regions in the US, and (2) no special consideration for income or gender need be made in surveys of population groups to determine Se status.

  16. Acute Rheumatic Fever in Los Angeles County

    PubMed Central

    Propp, Richard P.

    1965-01-01

    There was a general downward trend in the reported incidence of acute rheumatic fever in Los Angeles County during the years 1954-1963. A survey of hospital records in five large hospitals in 1962 revealed 100 cases diagnosed, 39 of which were reported. Diagnoses in the charts reviewed conformed to the Modified Jones Criteria. Most of the patients were born in Los Angeles County. Mortality rates for acute rheumatic fever during the same period were greatly in excess of those expected from the reported morbidity. The mean crude mortality rate for the period concerned was higher than for New York City, although not as high as for Boston. Acute rheumatic fever appears to constitute a health problem in need of review in Los Angeles County. PMID:5834286

  17. Cost effective operations through informed risk taking at the DuPage County wastewater facility Knollwood WWTP phase III

    SciTech Connect

    Rafter, J.C.; Palmer, R.A.; Bowles, B.

    1998-07-01

    Using a proactive approach to responsible wastewater collection and treatment, DuPage County, Illinois in conjunction with CTE identified and presented adverse compliance challenges to the IEPA regarding the capabilities of the Region IX-East collection and treatment facilities. This approach contained an element of risk on the County's part, knowing that the IEPA's non-compliance penalties regarding these issues were severe and that a resolution within a court ordered time schedule. A careful plan was developed to involve all the parties, the County, the regulatory agencies, the engineer and the contractor to solve the potential challenges facing the County based on anticipated increases in wastewater flow due to population growth in the Region. Regional IX-Easts' customers are served by the Knollwood Wastewater Treatment Plant (Knollwood). The Knollwood site is located just north of forest preserve property along the Des Plaines River in Burr Ridge, Illinois. The surrounding area to the west consists of a commercial industrial park. A residential development is located to the north of the plant approximately 1000 feet from the nearest treatment plant processing unit. The Knollwood Plant was rated to treat an average daily flow of 8.3 mgd prior to the construction of the new facilities. The new facilities allow the plant to treat an average daily flow of 10 mgd and peak flows up to 50 mgd.

  18. BIOSENSORS FOR ENVIRONMENTAL MONITORING: A REGULATORY PERSPECTIVE

    EPA Science Inventory

    Biosensors show the potential to complement laboratory-based analytical methods for environmental applications. Although biosensors for potential environmental-monitoring applications have been reported for a wide range of environmental pollutants, from a regulatory perspective, ...

  19. 21 CFR 26.18 - Regulatory collaboration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS, AND CERTAIN MEDICAL DEVICE PRODUCT EVALUATION REPORTS: UNITED STATES AND THE EUROPEAN COMMUNITY Specific Sector Provisions for Pharmaceutical Good Manufacturing Practices § 26.18 Regulatory...

  20. Electricity distribution networks: Changing regulatory approaches

    NASA Astrophysics Data System (ADS)

    Cambini, Carlo

    2016-09-01

    Increasing the penetration of distributed generation and smart grid technologies requires substantial investments. A study proposes an innovative approach that combines four regulatory tools to provide economic incentives for distribution system operators to facilitate these innovative practices.

  1. 21 CFR 26.18 - Regulatory collaboration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... Specific Sector Provisions for Pharmaceutical Good Manufacturing Practices § 26.18 Regulatory...

  2. EVOLUTIONARY BIOSCIENCE AS REGULATORY SYSTEMS BIOLOGY

    PubMed Central

    Davidson, Eric H.

    2011-01-01

    At present several entirely different explanatory approaches compete to illuminate the mechanisms by which animal body plans have evolved. Their respective relevance is briefly considered here in the light of modern knowledge of genomes and the regulatory processes by which development is controlled. Just as development is a system property of the regulatory genome, so causal explanation of evolutionary change in developmental process must be considered at a system level. Here I enumerate some mechanistic consequences that follow from the conclusion that evolution of the body plan has occurred by alteration of the structure of developmental gene regulatory networks. The hierarchy and multiple additional design features of these networks act to produce Boolean regulatory state specification functions at upstream phases of development of the body plan. These are created by the logic outputs of network subcircuits, and in modern animals these outputs are impervious to continuous adaptive variation unlike genes operating more peripherally in the network. PMID:21320483

  3. REGULATORY APPLICATIONS OF POREWATER TOXICITY TESTING

    EPA Science Inventory

    The purpose of this chapter is to evaluate the use of porewater toxicity tests in regulatory applications, including their potential use in the development of sediment quality guideline (SQG) values. Specifically, the following discussion focuses on the appropriateness and readin...

  4. 77 FR 26413 - Promoting International Regulatory Cooperation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... global economy, international regulatory cooperation, consistent with domestic law and prerogatives and U... HOUSE, May 1, 2012. [FR Doc. 2012-10968 Filed 5-3-12; 8:45 am] Billing code 3295-F2-P...

  5. 21 CFR 26.34 - Regulatory authorities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... and monitoring of conformity assessment bodies (CAB's). Regulatory authorities will be specified...

  6. 21 CFR 26.34 - Regulatory authorities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... and monitoring of conformity assessment bodies (CAB's). Regulatory authorities will be specified...

  7. 21 CFR 500.88 - Regulatory method.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... regulatory method must be able to confirm the identity of the marker residue in the target tissue at a... ascertaining the marker residue in the target tissue in accordance with the provisions of sections...

  8. Regulatory focus in predictions about others.

    PubMed

    Woltin, Karl-Andrew; Yzerbyt, Vincent

    2015-03-01

    Based on social projection research, four studies investigated whether people rely on their own regulatory focus when making predictions about others. Chronic (Study 1) and induced (Study 2) regulatory focus shaped estimations of others' strategic promotion or prevention inclinations and choices between enriched (fitting promotion) and impoverished options (fitting prevention). Providing indirect process evidence via boundary conditions, participants only relied on their induced regulatory focus in predictions of others' inclinations to seek romantic alternatives to the extent that this did not run counter to stereotypic gender beliefs (Study 3). In addition, participants only relied on their induced regulatory focus in preference predictions concerning promotion and prevention products when they lacked idiosyncratic target knowledge (Study 4). These effects were not mediated by mood, judgment-certainty, perceived task-enjoyment, or task-difficulty. Implications of these findings for social projection research as well as possible interpersonal consequences are delineated.

  9. Day Fire in Ventura County

    NASA Technical Reports Server (NTRS)

    2006-01-01

    [figure removed for brevity, see original site] Annotated Version

    The Day fire has been burning in Ventura County in Southern California since Labor Day, and has consumed more than 160,000 acres. As of September 29, it was 63 percent contained. The Advanced Spaceborne Thermal Emission and Reflection Radiometer on NASA's Terra satellite flew over the fire at 10 p.m. Pacific Time on September 28, and imaged the fire with its infrared camera. The hottest areas of active burning appear as red spots on the image. The blue-green background is a daytime image acquired in June, used as a background to allow firefighters to localize the hot spots.

    With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission directorate.

    Size: 22.5 by 31.0 kilometers (12.6 by 15.2 miles) Location: 34

  10. Energy Efficient Buildings, Salt Lake County, Utah

    SciTech Connect

    Barnett, Kimberly

    2012-04-30

    Executive Summary Salt Lake County's Solar Photovoltaic Project - an unprecedented public/private partnership Salt Lake County is pleased to announce the completion of its unprecedented solar photovoltaic (PV) installation on the Calvin R. Rampton Salt Palace Convention Center. This 1.65 MW installation will be one the largest solar roof top installations in the country and will more than double the current installed solar capacity in the state of Utah. Construction is complete and the system will be operational in May 2012. The County has accomplished this project using a Power Purchase Agreement (PPA) financing model. In a PPA model a third-party solar developer will finance, develop, own, operate, and maintain the solar array. Salt Lake County will lease its roof, and purchase the power from this third-party under a long-term Power Purchase Agreement contract. In fact, this will be one of the first projects in the state of Utah to take advantage of the recent (March 2010) legislation which makes PPA models possible for projects of this type. In addition to utilizing a PPA, this solar project will employ public and private capital, Energy Efficiency and Conservation Block Grants (EECBG), and public/private subsidized bonds that are able to work together efficiently because of the recent stimulus bill. The project also makes use of recent changes to federal tax rules, and the recent re-awakening of private capital markets that make a significant public-private partnership possible. This is an extremely innovative project, and will mark the first time that all of these incentives (EECBG grants, Qualified Energy Conservation Bonds, New Markets tax credits, investment tax credits, public and private funds) have been packaged into one project. All of Salt Lake County's research documents and studies, agreements, and technical information is available to the public. In addition, the County has already shared a variety of information with the public through webinars

  11. 51. Photographer unknown 1930 HUMBOLDT COUNTY, SECTION A, HIGHWAY 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Photographer unknown 1930 HUMBOLDT COUNTY, SECTION A, HIGHWAY 1. 1-HUM-1-A #101, MEASURING BETWEEN TREES, 1930. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  12. 44. Photographer unknown Date unknown MENDOCINO COUNTY, SECTION, HIGHWAY 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Photographer unknown Date unknown MENDOCINO COUNTY, SECTION, HIGHWAY 1. 1-MEN-1-I #9, MOVING CAMP. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  13. Los Angeles County Poor Farm, Patient Ward Nos. 210 & ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Los Angeles County Poor Farm, Patient Ward Nos. 210 & 211 - Type B Plan, 7601 Imperial Highway; bounded by Esperanza Street, Laurel Street, Flores Street, and Descanso Street, Downey, Los Angeles County, CA

  14. Los Angeles County Poor Farm, Patient Wards 201, 202, 203, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Los Angeles County Poor Farm, Patient Wards 201, 202, 203, 204, 205, 206, 207, 208 & 209 - Type A Plan, 7601 Imperial Highway; bounded by Esperanza Street, Hawthorn Avenue, Laurel Street, and Descanso Street, Downey, Los Angeles County, CA

  15. 76 FR 45770 - Tehama County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... Forest Service Tehama County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Tehama County Resource Advisory Committee (RAC) will meet in Red Bluff, California... comments. FOR FURTHER INFORMATION CONTACT: Randy Jero, Committee Coordinator, USDA, Mendocino...

  16. 76 FR 28729 - Tehama County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... Forest Service Tehama County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Tehama County Resource Advisory Committee (RAC) will meet in Red Bluff, California... comments. FOR FURTHER INFORMATION CONTACT: Randy Jero, Committee Coordinator, USDA, Mendocino...

  17. 22. Historic American Buildings Survey Alameda County Recorder Office Map ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Historic American Buildings Survey Alameda County Recorder Office Map Book 6, page 17 October 1960 SURVEY OF 1868 - Mission San Jose de Guadalupe, Mission & Washington Boulevards, Fremont, Alameda County, CA

  18. 20. Photocopy of photograph (from the Bucks County Historical Society) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopy of photograph (from the Bucks County Historical Society) photographer and date unknown GENERAL VIEW FROM THE SOUTHWEST - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

  19. 26. Photocopy of drawing (original in possession of Allegany County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) HEADER BUILDING, ELEVATIONS OF WEST SIDE ON COL LINE AH AND AP, 1920 - Kelly-Springfield Tire Plant, Factory Building, 701 Kelly Road, Cumberland, Allegany County, MD

  20. 27. Photocopy of drawing (original in possession of Allegany County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) FACTORY BUILDING, PLAN OF FLOOR B, 1928, NOTE OPEN COURTS - Kelly-Springfield Tire Plant, Factory Building, 701 Kelly Road, Cumberland, Allegany County, MD

  1. 5. Photocopy of drawing (original in possession of Allegany County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) FIRST FLOOR PLAN, BOILER AND POWER HOUSE, 1922 - Kelly-Springfield Tire Plant, Power House, 701 Kelly Road, Cumberland, Allegany County, MD

  2. 28. Photocopy of drawing (original in possession of Allegany County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) FACTORY BUILDING, PLAN OF FLOOR B, MACHINERY LAYOUT, 1943, NOTE INFILLED COURTS - Kelly-Springfield Tire Plant, Factory Building, 701 Kelly Road, Cumberland, Allegany County, MD

  3. 25. Photocopy of drawing (original in possession of Allegany County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) COURT 4, SECTION BETWEEN COLS. 51 AND 52, LOOKING NORTH, NOTE MONITOR WINDOW, 1920 - Kelly-Springfield Tire Plant, Factory Building, 701 Kelly Road, Cumberland, Allegany County, MD

  4. Photocopy of drawing (original In possession of Allegany County, Cumberland, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (original In possession of Allegany County, Cumberland, MD) WELL WATER RESERVOIR, 1926 - Kelly-Springfield Tire Plant, Cooling Tower, 701 Kelly Road, Cumberland, Allegany County, MD

  5. Photocopy of drawing (original in possession of Allegany County, Cumberland, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (original in possession of Allegany County, Cumberland, MD) CEMENT HOUSE FLOOR PLAN, 1942 - Kelly-Springfield Tire Plant, Cement House, 701 Kelly Road, Cumberland, Allegany County, MD

  6. 75 FR 14124 - Ravalli County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Forest Service Ravalli County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Ravalli County Resource Advisory Committee will meet in Hamilton, Montana....

  7. 76 FR 16725 - Ravalli County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Forest Service Ravalli County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Ravalli County Resource Advisory Committee will meet in Hamilton, Montana....

  8. 76 FR 12691 - Ravalli County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Forest Service Ravalli County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Ravalli County Resource Advisory Committee will meet in Hamilton, Montana....

  9. 76 FR 31297 - Ravalli County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Forest Service Ravalli County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. ] SUMMARY: The Ravalli County Resource Advisory Committee will meet in Hamilton, Montana....

  10. 76 FR 21701 - Ravalli County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Forest Service Ravalli County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Ravalli County Resource Advisory Committee will meet in Hamilton, Montana....

  11. 15. Photocopy of photograph (from Chester County Historical Society) ca. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy of photograph (from Chester County Historical Society) ca. 1905, photographer unknown NORTH REAR - John Chad House, State Route 100, U.S. Route 1 vicinity, Chadds Ford, Delaware County, PA

  12. 17. Photocopy of photograph (source uncertain; probably the Bucks County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of photograph (source uncertain; probably the Bucks County Historical Society) ca. 1913, photographer unknown SHOWING 1904 SOCIETY HEADQUARTERS AND THE EARLY PHASES OF CONSTRUCTION ON MERCER'S ADDITION - Mercer Museum, Pine & Ashland Streets, Doylestown, Bucks County, PA

  13. GENERAL SITE PLAN, HAMILTON AIR FORCE BASE, MARIN COUNTY, CALIFORNIA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL SITE PLAN, HAMILTON AIR FORCE BASE, MARIN COUNTY, CALIFORNIA. Pencil on paper, dated December 4, 1952. Also marked "PWC 103474." By J.Y. Long Company, Engineers, Oakland, California - Hamilton Field, East of Nave Drive, Novato, Marin County, CA

  14. 75 FR 52804 - Environmental Impact Statement: Stanislaus County, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... Federal Highway Administration Environmental Impact Statement: Stanislaus County, CA AGENCY: Federal... Environmental Impact Statement (EIS) will be prepared for a proposed highway project in Stanislaus County... subsequent environmental documentation for project-specific impacts. Letters describing the proposed...

  15. 75 FR 62627 - Environmental Impact Statement; Davis County, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Federal Highway Administration Environmental Impact Statement; Davis County, UT AGENCY: Federal Highway... that an Environmental Impact Statement (EIS) will be prepared for proposed transportation improvements in Davis County, Utah. FOR FURTHER INFORMATION CONTACT: Edward Woolford, Environmental...

  16. 48. Photographer unknown February 1925 MENDOCINO COUNTY, SECTION K, HIGHWAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    48. Photographer unknown February 1925 MENDOCINO COUNTY, SECTION K, HIGHWAY 1. 1-MEN-1-K #39, LOG GUARD RAIL, 2-25. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  17. 8. VIEW OF YOLO COUNTY ELEVATION, LOOKING EASTSOUTHEAST TOWARD SACRAMENTO, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF YOLO COUNTY ELEVATION, LOOKING EAST-SOUTHEAST TOWARD SACRAMENTO, ALONG CENTERLINE OF STATE HIGHWAY 275 - Sacramento River Bridge, Spanning Sacramento River at California State Highway 275, Sacramento, Sacramento County, CA

  18. 44. PRECONSTRUCTION PHOTOGRAPH, LOOKING WESTNORTHWEST INTO YOLO COUNTY FROM OPEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. PRE-CONSTRUCTION PHOTOGRAPH, LOOKING WEST-NORTHWEST INTO YOLO COUNTY FROM OPEN SWING SPAN OF M STREET BRIDGE, mid-1934 - Sacramento River Bridge, Spanning Sacramento River at California State Highway 275, Sacramento, Sacramento County, CA

  19. 48. EXCAVATING AND DRIVING PILES FOR SHOOFLY BRIDGE, YOLO COUNTY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    48. EXCAVATING AND DRIVING PILES FOR SHOOFLY BRIDGE, YOLO COUNTY SIDE OF RIVER, November 7, 1934 - Sacramento River Bridge, Spanning Sacramento River at California State Highway 275, Sacramento, Sacramento County, CA

  20. 18. Photocopy of photograph (original print in Chester County Historical ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of photograph (original print in Chester County Historical Society, West Chester, Pennsylvania) Circa 1905, photographer unknown SOUTH FRONT AND WEST SIDE - Barnes-Brinton House, 630 Baltimore Pike (U.S. Route 1), Chadds Ford, Delaware County, PA

  1. View east, barn, west elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east, barn, west elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  2. View north, barn, south elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north, barn, south elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  3. View west, barn, east elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west, barn, east elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  4. View south, barn, north elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south, barn, north elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  5. 5. TUNNEL TREE AT DRIVETHROUGHTREE PARK. LEGGETT, HUMBOLDT COUNTY, CALIFORNIA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. TUNNEL TREE AT DRIVE-THROUGH-TREE PARK. LEGGETT, HUMBOLDT COUNTY, CALIFORNIA. LOOKING NE. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  6. 15. Photocopy from Futhey and Cope's History of Chester County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy from Futhey and Cope's History of Chester County, Pennsylvania, 1881, facing page 27 VIEW OF FARM - Joseph Jackson House, Old Baltimore Pike (London Grove Township), West Grove, Chester County, PA

  7. Team structure and regulatory focus: the impact of regulatory fit on team dynamic.

    PubMed

    Dimotakis, Nikolaos; Davison, Robert B; Hollenbeck, John R

    2012-03-01

    We report a within-teams experiment testing the effects of fit between team structure and regulatory task demands on task performance and satisfaction through average team member positive affect and helping behaviors. We used a completely crossed repeated-observations design in which 21 teams enacted 2 tasks with different regulatory focus characteristics (prevention and promotion) in 2 organizational structures (functional and divisional), resulting in 84 observations. Results suggested that salient regulatory demands inherent in the task interacted with structure to determine objective and subjective team-level outcomes, such that functional structures were best suited to (i.e., had best fit with) tasks with a prevention regulatory focus and divisional structures were best suited to tasks with a promotion regulatory focus. This contingency finding integrates regulatory focus and structural contingency theories, and extends them to the team level with implications for models of performance, satisfaction, and team dynamics. PMID:22181678

  8. Team structure and regulatory focus: the impact of regulatory fit on team dynamic.

    PubMed

    Dimotakis, Nikolaos; Davison, Robert B; Hollenbeck, John R

    2012-03-01

    We report a within-teams experiment testing the effects of fit between team structure and regulatory task demands on task performance and satisfaction through average team member positive affect and helping behaviors. We used a completely crossed repeated-observations design in which 21 teams enacted 2 tasks with different regulatory focus characteristics (prevention and promotion) in 2 organizational structures (functional and divisional), resulting in 84 observations. Results suggested that salient regulatory demands inherent in the task interacted with structure to determine objective and subjective team-level outcomes, such that functional structures were best suited to (i.e., had best fit with) tasks with a prevention regulatory focus and divisional structures were best suited to tasks with a promotion regulatory focus. This contingency finding integrates regulatory focus and structural contingency theories, and extends them to the team level with implications for models of performance, satisfaction, and team dynamics.

  9. Advancing a Vision for Regulatory Science Training.

    PubMed

    Adamo, Joan E; Wilhelm, Erin E; Steele, Scott J

    2015-10-01

    Regulatory science, a complex field which draws on science, law, and policy, is a growing discipline in medical-related applications. Competencies help define both a discipline and the criteria to measure high-quality learning experiences. This paper identifies competencies for regulatory science, how they were developed, and broader recommendations to enhance education and training in this burgeoning field, including a multifaceted training approach.

  10. ATMPs for Cancer Immunotherapy: A Regulatory Overview.

    PubMed

    Galli, Maria Cristina

    2016-01-01

    This chapter discusses European regulatory requirements for development of advanced therapy medicinal products (ATMP) for cancer immunotherapy approaches, describing the framework for clinical trials and for marketing authorization.Regulatory critical issues and challenges for developing ATMP are also discussed, with focus on potency determination, long-term follow-up, comparability, and insertional mutagenesis issues. Some of the most critical features of GMP application to ATMP are also described.

  11. Mission Risk Reduction Regulatory Change Management

    NASA Technical Reports Server (NTRS)

    Scroggins, Sharon

    2007-01-01

    NASA Headquarters Environmental Management Division supports NASA's mission to pioneer the future in space exploration, scientific discovery, and aeronautics research by integrating environmental considerations into programs and projects early-on, thereby proactively reducing NASA's exposure to institutional, programmatic and operational risk. As part of this effort, NASA established the Principal Center for Regulatory Risk Analysis and Communication (RRAC PC) as a resource for detecting, analyzing, and communicating environmental regulatory risks to the NASA stakeholder community. The RRAC PC focuses on detecting emerging environmental regulations and other operational change drivers that may pose risks to NASA programs and facilities, and effectively communicating the potential risks. For example, regulatory change may restrict how and where certain activities or operations may be conducted. Regulatory change can also directly affect the ability to use certain materials by mandating a production phase-out or restricting usage applications of certain materials. Regulatory change can result in significant adverse impacts to NASA programs and facilities due to NASA's stringent performance requirements for materials and components related to human-rated space vehicles. Even if a regulation does not directly affect NASA operations, U.S. and international regulations can pose program risks indirectly through requirements levied on manufacturers and vendors of components and materials. For example, manufacturers can change their formulations to comply with new regulatory requirements. Such changes can require time-consuming and costly requalification certification for use in human spaceflight programs. The RRAC PC has implemented a system for proactively managing regulatory change to minimize potential adverse impacts to NASA programs and facilities. This presentation highlights the process utilized by the RRACPC to communicate regulatory change and the associated

  12. Regulatory changes for international satellite systems

    NASA Astrophysics Data System (ADS)

    Roseman, Walda W.

    Proposals for mobile and broadcast satellite systems and advances in fixed satellite systems and applications are placing new demands on governments to find efficient means of access to spectrum and create regulatory policies that facilitate the cross-border harmonization of satellite services. In an environment where liberalization is proceeding, but doing so unevenly, special responsibilities devolve to consumers and to the satellite enterprises themselves to ensure that an appropriate international regulatory framework is adopted.

  13. Regulatory frameworks for mobile medical applications.

    PubMed

    Censi, Federica; Mattei, Eugenio; Triventi, Michele; Calcagnini, Giovanni

    2015-05-01

    A mobile application (app) is a software program that runs on mobile communication devices such as a smartphone. The concept of a mobile medical app has gained popularity and diffusion but its reference regulatory context has raised discussion and concerns. Theoretically, a mobile app can be developed and uploaded easily by any person or entity. Thus, if an app can have some effects on the health of the users, it is mandatory to identify its reference regulatory context and the applicable prescriptions.

  14. Geologic Map of Loudoun County, Virginia

    USGS Publications Warehouse

    Southworth, Scott; Burton, William C.; Schindler, J. Stephen; Froelich, Albert J.

    2006-01-01

    Introduction The geology of Loudoun County, Va., was mapped from 1988 through 1991 under a cooperative agreement between the U.S. Geological Survey (USGS) and the Loudoun County Office of Mapping and Geographic Information. This geologic map was compiled in 1993 from a series of detailed published and unpublished field investigations at scales of 1:12,000 and 1:24,000. Some of these same data were compiled as a digital geologic map at 1:100,000 scale (Burton and others, 1992a) and were the basis for a cost-benefit analysis of the societal value of geologic maps (Bernknopf and others, 1993).

  15. Apprehending multicellularity: regulatory networks, genomics and evolution

    PubMed Central

    Aravind, L.; Anantharaman, Vivek; Venancio, Thiago M.

    2009-01-01

    The genomic revolution has provided the first glimpses of the architecture of regulatory networks. Combined with evolutionary information, the “network view” of life processes leads to remarkable insights into how biological systems have been shaped by various forces. This understanding is critical because biological systems, including regulatory networks, are not products of engineering but of historical contingencies. In this light, we attempt a synthetic overview of the natural history of regulatory networks operating in the development and differentiation of multicellular organisms. We first introduce regulatory networks and their organizational principles as can be deduced using ideas from the graph theory. We then discuss findings from comparative genomics to illustrate the effects of lineage-specific expansions, gene-loss, and non-protein-coding DNA on the architecture of networks. We consider the interaction between expansions of transcription factors, and cis regulatory and more general chromatin state stabilizing elements in the emergence of morphological complexity. Finally, we consider a case study of the Notch sub-network, which is present throughout Metazoa, to examine how such a regulatory system has been pieced together in evolution from new innovations and pre-existing components that were originally functionally distinct. PMID:19530132

  16. Cis-regulatory mutations in human disease

    PubMed Central

    2009-01-01

    Cis-acting regulatory sequences are required for the proper temporal and spatial control of gene expression. Variation in gene expression is highly heritable and a significant determinant of human disease susceptibility. The diversity of human genetic diseases attributed, in whole or in part, to mutations in non-coding regulatory sequences is on the rise. Improvements in genome-wide methods of associating genetic variation with human disease and predicting DNA with cis-regulatory potential are two of the major reasons for these recent advances. This review will highlight select examples from the literature that have successfully integrated genetic and genomic approaches to uncover the molecular basis by which cis-regulatory mutations alter gene expression and contribute to human disease. The fine mapping of disease-causing variants has led to the discovery of novel cis-acting regulatory elements that, in some instances, are located as far away as 1.5 Mb from the target gene. In other cases, the prior knowledge of the regulatory landscape surrounding the gene of interest aided in the selection of enhancers for mutation screening. The success of these studies should provide a framework for following up on the large number of genome-wide association studies that have identified common variants in non-coding regions of the genome that associate with increased risk of human diseases including, diabetes, autism, Crohn's, colorectal cancer, and asthma, to name a few. PMID:19641089

  17. 71. MISSISSIPPI, LOWNDES CO. COLUMBUSSTEENS MAP OF LOWNDES COUNTY, 1931 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    71. MISSISSIPPI, LOWNDES CO. COLUMBUS-STEENS MAP OF LOWNDES COUNTY, 1931 Detail of ROAD MAP OF LOWNDES COUNTY, MISSISSIPPI, 1931 by C. L. wood, county engineer. Orig. scale: I in. to I mi. Includes Columbus and area NE to steens. Extent: 12 mi. East-West, 9 mi. North-South. Property of Helen (Mrs. Sam L.) Crawford, Hamilton, Ms. Sarcone Photography, Columbus, Ms., Sep 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  18. 70. MISSISSIPPI, LOWNDES CO., NORTHWEST CORNER MAP OF LOWNDES COUNTY, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    70. MISSISSIPPI, LOWNDES CO., NORTHWEST CORNER MAP OF LOWNDES COUNTY, 1931 Detail of ROAD OF LOWNDES COUNTY, MISSISSIPPI, 1931 by C. L. wood, county engineer. Detail of section NW of Columbus (12 mi. N, 9 mi. W), including Plymouth, Waverly, Barton, Buttahatchie R. Orig. scale: 1 in. to 1 mi. Property of Helen (Mrs. Sam L.) Crawford, Hamilton, Ms. Sarcone Photography, Columbus, Ms., Sep 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  19. 43. Photographer unknown February 1925 MENDOCINO COUNTY, SECTION, HIGHWAY 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Photographer unknown February 1925 MENDOCINO COUNTY, SECTION, HIGHWAY 1. 1-MEN-1-1 #12, NEW HIGHWAY DISPLACING OLD COUNTY ROAD, 2-25. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  20. 7. Photocopy of map (from Superior Court of Chatham County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of map (from Superior Court of Chatham County Land Records, Book 2G, p. 299) John McKinnon (County Surveyor), delineator 11 January 1817 PLAT OF SITE, SHOWING EASTERN PORTION OF BUILDING - William Taylor Store, 204 West Bay Street, Savannah, Chatham County, GA

  1. 76 FR 26240 - Big Horn County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... Forest Service Big Horn County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Big Horn County Resource Advisory Committee will meet in Greybull, Wyoming..., 2011, and will begin at 10 a.m. ADDRESSES: The meeting will be held at the Big Horn County Weed...

  2. 78 FR 33326 - Big Horn County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Forest Service Big Horn County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Big Horn County Resource Advisory Committee will meet in Greybull, Wyoming... at 3:00 p.m. ADDRESSES: The meeting will be held at Big Horn County Weed and Pest Building,...

  3. 76 FR 47141 - Big Horn County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... Forest Service Big Horn County Resource Advisory Committee AGENCY: Forest Service, USDA. ] ACTION: Notice of meeting. SUMMARY: The Big Horn County Resource Advisory Committee will meet in Greybull, Wyoming..., 2011 and will begin at 3 p.m. ADDRESSES: The meeting will be held at the Big Horn County Weed and...

  4. 77 FR 49779 - Big Horn County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... Forest Service Big Horn County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Big Horn County Resource Advisory Committee will meet in Greybull, Wyoming... 11, 2012 and will begin at 3 p.m. ADDRESSES: The meeting will be held at the Big Horn County Weed...

  5. 75 FR 71069 - Big Horn County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... Forest Service Big Horn County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Big Horn County Resource Advisory Committee will meet in Greybull, Wyoming... December 1, 2010, and will begin at 10 a.m. ADDRESSES: The meeting will be held at the Big Horn County...

  6. 75 FR 4417 - Wind Cave National Park, Custer County, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Wind Cave National Park, Custer County, SD AGENCY: National Park Service. ACTION: Notice of... Statement, Wind Cave National Park, Custer County, South Dakota. SUMMARY: Pursuant to Section 102(2)(C) of... Environmental Impact Statement (Plan), Wind Cave National Park, Custer County, South Dakota. On December 3,...

  7. 77 FR 57556 - Lake County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-18

    ... Forest Service Lake County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of Meeting. SUMMARY: The Lake County Resource Advisory Committee (RAC) will hold a meeting. DATES: The... the Lake County Board of Supervisor's Chambers at 255 North Forbes Street, Lakeport or Conference...

  8. 76 FR 7531 - Lake County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... Forest Service Lake County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Lake County Resource Advisory Committee (RAC) will hold a meeting. DATES: The... Lake County Board of Supervisor's Chambers at 255 North Forbes Street, Lakeport or Conference Room...

  9. A Plan of Library Services for Pinellas County, Florida.

    ERIC Educational Resources Information Center

    Summers, F. William; Curran, Charles C.

    In order to determine the feasibility of establishing a county-wide library system, the Pinellas County (Florida) Board of County Commissioners authorized a study of existing library services and possible alternatives for reorganization. Data were gathered and analyzed from: (1) questionnaires sent to library directors; (2) interviews with these…

  10. 7 CFR 7.12 - Composition of a county committee.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Composition of a county committee. 7.12 Section 7.12 Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF FARM SERVICE AGENCY STATE AND COUNTY COMMITTEES § 7.12 Composition of a county committee. (a) A committee established under this...

  11. 7 CFR 7.12 - Composition of a county committee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Composition of a county committee. 7.12 Section 7.12 Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF FARM SERVICE AGENCY STATE AND COUNTY COMMITTEES § 7.12 Composition of a county committee. (a) A committee established under this...

  12. 27 CFR 9.190 - Red Hill Douglas County, Oregon.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Red Hill Douglas County... Areas § 9.190 Red Hill Douglas County, Oregon. (a) Name. The name of the viticultural area described in this section is “Red Hill Douglas County, Oregon”. For purposes of part 4 of this chapter, “Red...

  13. 17. "Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. "Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, California, A.J. Logan, County Surveyor, H.J. Brunnier, Consulting Engineer, March 7, 1919," showing plan of bars in top flange, elevation of girder reinforcement, plan of bars in bottom flange - Salt River Bridge, Spanning Salt River at Dillon Road, Ferndale, Humboldt County, CA

  14. 18. "Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. "Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, California, A.J. Logan, County Surveyor, H.J. Brunnier, Consulting Engineer, March 7, 1919," showing elevation of center pier, elevation and plan of north and south abutments, sections of abutments, pier, and pier footings - Salt River Bridge, Spanning Salt River at Dillon Road, Ferndale, Humboldt County, CA

  15. 15. 'Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. 'Concrete Bridge Over Salt River, Port Kenyon, Humboldt County, California, A.J. Logan, County Surveyor, H.J. Brunnier, Consulting Engineer, March 7, 1919,' showing general plan, plan of top chord, elevation of main girder, transverse section, plan section at deck level. - Salt River Bridge, Spanning Salt River at Dillon Road, Ferndale, Humboldt County, CA

  16. County-level environmental quality and associations with individual - and county-level preterm birth

    EPA Science Inventory

    Human health is influenced by simultaneous exposure to stressors and amenities, but research usually considers single exposures. We constructed a county-level Environmental Quality Index (EQI) using principal components analysis with data from five domains (air, water, land, buil...

  17. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; Door County, WI. (a) Regulated Area. A regulated area is established to include all waters of Green Bay... effective July 22, 2007, July 26 and 27, 2008, July 25 and 26, 2009, July 24 and 25, 2010, July 23 and...

  18. Evolution of splicing regulatory networks in Drosophila

    PubMed Central

    McManus, C. Joel; Coolon, Joseph D.; Eipper-Mains, Jodi; Wittkopp, Patricia J.; Graveley, Brenton R.

    2014-01-01

    The proteome expanding effects of alternative pre-mRNA splicing have had a profound impact on eukaryotic evolution. The events that create this diversity can be placed into four major classes: exon skipping, intron retention, alternative 5′ splice sites, and alternative 3′ splice sites. Although the regulatory mechanisms and evolutionary pressures among alternative splicing classes clearly differ, how these differences affect the evolution of splicing regulation remains poorly characterized. We used RNA-seq to investigate splicing differences in D. simulans, D. sechellia, and three strains of D. melanogaster. Regulation of exon skipping and tandem alternative 3′ splice sites (NAGNAGs) were more divergent than other splicing classes. Splicing regulation was most divergent in frame-preserving events and events in noncoding regions. We further determined the contributions of cis- and trans-acting changes in splicing regulatory networks by comparing allele-specific splicing in F1 interspecific hybrids, because differences in allele-specific splicing reflect changes in cis-regulatory element activity. We find that species-specific differences in intron retention and alternative splice site usage are primarily attributable to changes in cis-regulatory elements (median ∼80% cis), whereas species-specific exon skipping differences are driven by both cis- and trans-regulatory divergence (median ∼50% cis). These results help define the mechanisms and constraints that influence splicing regulatory evolution and show that networks regulating the four major classes of alternative splicing diverge through different genetic mechanisms. We propose a model in which differences in regulatory network architecture among classes of alternative splicing affect the evolution of splicing regulation. PMID:24515119

  19. Counseling Survey: Crook County Middle School.

    ERIC Educational Resources Information Center

    Zachow, Kathleen; Carter, Gary

    This paper reports the results of a counseling survey completed by 523 middle school students at Crook County Middle School, Prineville, Oregon, to provide data regarding student concerns in the areas of health and growth, personality, school, home and family, friends, and the future. Results are reported for each of the six categories by grade…

  20. The Fairfax County Family Literacy Curriculum.

    ERIC Educational Resources Information Center

    Wong, Betsy Lindeman

    The Fairfax County Family Literacy Curriculum is designed to be used in a multi-level adult English for Speakers of Other Languages (ESOL) family literacy class. There are four modules to choose from: Introductory (self, family, and community); Government (schools and community); Health (medicine and stress); and Consumerism (shopping and making a…

  1. Clark County Health Manpower and Education Profile.

    ERIC Educational Resources Information Center

    Callen, John; And Others

    The profile is a concise description of the demographic and economic characteristics, existing health manpower employed, and health education programs for the Clark County area of Nevada, one of seven surveyed in the Mountain States region (Idaho, Montana, Wyoming, and Nevada). The first section of the profile provides general population…

  2. Yellowstone County Health Manpower and Education Profile.

    ERIC Educational Resources Information Center

    Callen, John; And Others

    The profile is a concise description of the demographic and economic characteristics, existing health manpower employed, and health education programs for the Yellowstone County area of Montana, one of seven surveyed in the Mountain States region (Idaho, Montana, Wyoming, and Nevada). The first section of the profile provides general population…

  3. Sheridan County Health Manpower and Education Profile.

    ERIC Educational Resources Information Center

    Callen, John; And Others

    The profile is a concise description of the demographic and economic characteristics, existing health manpower employed, and health education programs for the Sheridan County area of Wyoming, one of seven surveyed in the Mountain States region (Idaho, Montana, Wyoming, and Nevada). The first section of the profile provides general population…

  4. Missoula County Health Manpower and Education Profile.

    ERIC Educational Resources Information Center

    Callen, John; And Others

    The profile is a concise description of the demographic and economic characteristics, existing health manpower employed, and health education programs for the Missoula County area of Montana, one of seven surveyed in the Mountain States region (Idaho, Montana, Wyoming, and Nevada). The first section of the profile provides general population…

  5. An Environmental Scan of Northern Alameda County.

    ERIC Educational Resources Information Center

    Galloro, Nicholas

    A study was conducted to provide an overview of the demographic and economic characteristics of the geographical area served by the Peralta Community College District and to provide population and economic projections up to the year 2000. Historical data from the Alameda County Planning Commission, census data, and projections from the Association…

  6. Food control concept: A county perspective

    SciTech Connect

    Calvert, B.E.

    1995-12-31

    This paper explains the Benton County, Washington responsibilities for implementing the ingestion exposure pathway protective actions. These responsibilities were successfully demonstrated in the September 13-14, 1994 FEMA evaluated exercise involving the Washington Public Power Supply System`s WNP-2 commercial nuclear power reactor.

  7. County Business Patterns: United States, 2002.

    ERIC Educational Resources Information Center

    US Department of Commerce, 2004

    2004-01-01

    In this report, subnational economic data by industry, including Educational Services, is provided. County Business Patterns is useful for studying the economic activity of small areas; analyzing economic changes over time; and as a benchmark for statistical series, surveys, and databases between economic censuses. The number of establishments,…

  8. Wind Energy Guide for County Commissioners

    SciTech Connect

    Costanti, M.

    2006-10-01

    One of the key stakeholders associated with economic development are local government officials, who are often required to evaluate and vote on commercial wind energy project permits, as well as to determine and articulate what wind energy benefits accrue to their counties. Often these local officials lack experience with large-scale wind energy and need to make important decisions concerning what may be a complicated and controversial issue. These decisions can be confounded with diverse perspectives from various stakeholders. This project is designed to provide county commissioners, planners, and other local county government officials with a practical overview of information required to successfully implement commercial wind energy projects in their county. The guidebook provides readers with information on the following 13 topics: Brief Wind Energy Overview; Environmental Benefits; Wind Energy Myths and Facts; Economic Development Benefits; Wind Economics; The Development Process; Public Outreach; Siting Issues; Property Tax Incentives; Power System Impacts; Permitting, Zoning, and Siting Processes; Case Studies; and Further Information. For each of the above topics, the guidebook provides an introduction that identifies the topic, why local government should care, a topic snapshot, how the topic will arise, and a list of resources that define and assess the topic.

  9. Geothermal development plan: northern Arizona counties

    SciTech Connect

    White, D.H.; Goldstone, L.A.

    1982-08-01

    The Northern Counties Area Development Plan evaluated the regional market potential for utilizing geothermal energy. This study identified five potential geothermal resource areas, four of which have low temperature (<90{sup 0}C, 194{sup 0}F) potential and one possible igneous system. The average population growth rate in the Northern Counties is expected to be five percent per year over the next 40 years, with Mohave and Yavapai Counties growing the fastest. Rapid growth is anticipated in all major employment sectors, including trade, service, manufacturing, mining and utilities. A regional energy use analysis is included, containing information on current energy use patterns for all user classes. Water supplies are expected to be adequate for expected growth generally, though Yavapai and Gila Counties will experience water deficiencies. A preliminary district heating analysis is included for the towns of Alpine and Springerville. Both communities are believed located on geothermal resource sites. The study also contains a section identifying potential geothermal resource users in northern Arizona.

  10. [A Profile of Union County, South Carolina].

    ERIC Educational Resources Information Center

    Lilley, Stephen C.; McLean, Edward L.

    Now almost totally dependent on textile production, heavily forested Union County, South Carolina, was primarily agricultural until the 20th century. By 1970, 65% of the population depended on manufacturing and only 4% of the workers on farming. From 1920 to 1970 the population was characterized by a rural-to-urban shift and by outmigration,…

  11. King County Division of Parks and Recreation.

    ERIC Educational Resources Information Center

    Iowa Univ., Iowa City. Recreation Education Program.

    Presented are duplications of the responses given by the King County Division of Parks and Recreation (Seattle, Washington) as part of a project to collect, share, and compile information about, and techniques in the operation of 18 community action models for recreation services to the disabled. Model programs are categorized as consumer, client…

  12. Public Schools. Cuyahoga County Data Brief

    ERIC Educational Resources Information Center

    Center on Urban Poverty and Community Development (NJ1), 2010

    2010-01-01

    Public school enrollment has fallen in most districts in Cuyahoga County, consistent with the overall population loss. The largest decreases of more than 30% have been in Cleveland and East Cleveland districts. Several inner ring suburbs have also experienced large declines, while a few outlying suburbs show increased enrollments. High school…

  13. The Fairfax County (Va.) Principals' Research Group.

    ERIC Educational Resources Information Center

    Endo, Todd

    1987-01-01

    Describes the activities developed for the "Students with Special Needs" group of the Fairfax County Principals' Research Group. The "Research Group" has shown that principals can implement ideas that do not emerge from any other source in the school system. (MD)

  14. Water availability of Washington County, Alabama

    USGS Publications Warehouse

    Newton, John G.; McCain, Jerald F.; Turner, James D.

    1975-01-01

    Large quantities of ground water and surface water are available in Washington County. Major sources of ground water are the Gosport Sand and Lisbon Formation undifferentiated, the Miocene Series undifferentiated, and alluvium and low terrace deposits. The Miocene, the most productive source of ground water, will yield 0.5 to 1.0 mgd (million gallons per day) per well and is a potential source of larger supplies in most of the county. The quantity of potable water available is governed largely by geologic structures. Average flows of the Tombigbee and Mobile Rivers in the southeast corner of the county are 18,200 and 39,400 mgd. Average runoff originating in the county is about 1,100 mgd or 1 mgd per square mile. Water in aquifers tapped by wells generally contains less than 500 mg/l (milligrams per liter) dissolved solids. The water generally is soft to moderately hard. Water in streams is soft to moderately hard and low in dissolved solids. Estimated water use in 1966 was 43.5 mgd of which 10.9 mgd was ground water and 32.6 mgd was surface water.

  15. Orange County Outdoor School: Teacher's Guide.

    ERIC Educational Resources Information Center

    Orange County Dept. of Education, Santa Ana, CA.

    Divided into six sections, the guide provides helpful information for the teacher to prepare students to attend the Orange County Outdoor School. Pre-camp responsibilities section provides pre-camp preparation checklists for the principal, teacher, parents, school nurse, and outdoor specialist; a checklist for morning departure; discipline policy…

  16. TV and Extension in Carbon County, Pa.

    ERIC Educational Resources Information Center

    Reitz, Ray W.

    To help improve televised extension education, a study was made of the interests and characteristics of the potential audience (9,300) of PTVC, a community antenna television system in Carbon County, Pennsylvania. A checklist questionnaire survey drew 160 usable responses from the communities of Jim Thorpe, Lehighton, and Palmerton. Data on…

  17. Cumberland County College Orientation Course Survey.

    ERIC Educational Resources Information Center

    Stolar, Steven M.

    In an effort to determine whether OR 100, a college success orientation seminar offered at New Jersey's Cumberland County College (CCC), should be upgraded to a college-level course and whether OR 101, a one-unit orientation course, should be required of all students, CCC surveyed 288 two- and four-year institutions in New Jersey, Delaware, and…

  18. Cumberland County College, AACC Progress Report.

    ERIC Educational Resources Information Center

    Cumberland County Coll., Vineland, NJ.

    In 1996, Cumberland County College (New Jersey) participated in the American Association of Community Colleges' Exploring America's Communities project, which works to strengthen the teaching and learning of American history, literature, and culture at U.S. community colleges. The primary goals of the college's action plan were: emphasizing…

  19. Charleston County School District (CCSD) Reading Policy.

    ERIC Educational Resources Information Center

    Charleston County School District, North Charleston, SC.

    This brief two-page policy statement presents the Charleston County (South Carolina) School District Board of Trustees reading policy. It begins by noting that the district will emphasize early literacy development, reading across the content areas, and interventions for struggling readers, and that schools shall be responsible for designing and…

  20. Water resources of Lincoln County, Wyoming

    USGS Publications Warehouse

    Eddy-Miller, C. A.; Plafcan, Maria; Clark, M.L.

    1996-01-01

    Streamflow and ground-water quantity and quality data were collected and analyzed, 1993 through 1995, and historical data were compiled to summarize the water resources of Lincoln County.Deposits of Quaternary age, in the valleys of the Bear River and Salt River, had the most well development of any geologic unit in the county.The most productive alluvial aquifers were located in the Bear River Valley and Star Valley with pumping wells discharging up to 2,000 gallons perminute. The ground-water connection between the Overthrust Belt and the Green River Basin is restricted as a result of the folding and faulting that occurred during middle Mesozoic and early Cenozoic time. Total water use in Lincoln County during 1993 was estimated to be 405,000 million gallons. Surface water was the source for 98 percent of the water used in the county. Hydroelectric power generation and irrigation used the largest amounts of water. Dissolved-solids concentrations varied greatly for water samples collected from 35 geologic units inventoried. Dissolved-solids concentrations in all water samples from the LaneyMember of the Green River Formation were greater than the Secondary Maximum Contaminant Level of 500 milligrams per liter established by the U.S. Environmental Protection Agency. Statistical analysis of data collected from wells in the Star Valley monitoring study indicated there was no significant difference between data collected during different seasons, and no correlation between the nitrate concentrations and depth to ground water.