Considerations for Improving the Capacity and Performance of AeroMACS

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Kamali, Behnam; Apaza, Rafael D.; Wilson, Jeffrey D.; Dimond, Robert P.

2014-01-01

The Aeronautical Mobile Airport Communications System (AeroMACS) has progressed from concept through prototype development, testing, and standards development and is now poised for the first operational deployments at nine US airports by the Federal Aviation Administration. These initial deployments will support fixed applications. Mobile applications providing connectivity to and from aircraft and ground-based vehicles on the airport surface will occur at some point in the future. Given that many fixed applications are possible for AeroMACS, it is necessary to now consider whether the existing capacity of AeroMACS will be reached even before the mobile applications are ready to be added, since AeroMACS is constrained by both available bandwidth and transmit power limitations. This paper describes some concepts that may be applied to improve the future capacity of AeroMACS, with a particular emphasis on gains that can be derived from the addition of IEEE 802.16j multihop relays to the AeroMACS standard, where a significant analysis effort has been undertaken.

Multicollision attack on CBC-MAC, EMAC, and XCBC-MAC of AES-128 algorithm

NASA Astrophysics Data System (ADS)

Brolin Sihite, Alfonso; Hayat Susanti, Bety

2017-10-01

A Message Authentication Codes (MAC) can be constructed based on a block cipher algorithm. CBC-MAC, EMAC, and XCBC-MAC constructions are some of MAC schemes that used in the hash function. In this paper, we do multicollision attack on CBC-MAC, EMAC, and XCBC-MAC construction which uses AES-128 block cipher algorithm as basic construction. The method of multicollision attack utilizes the concept of existential forgery on CBC-MAC. The results show that the multicollision can be obtained easily in CBC-MAC, EMAC, and XCBC-MAC construction.

28 CFR 513.36 - Government contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Government contractors. 513.36 Section 513.36 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Release of Information General Provisions and Procedures § 513.36 Government...

28 CFR 513.36 - Government contractors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Government contractors. 513.36 Section 513.36 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Release of Information General Provisions and Procedures § 513.36 Government...

28 CFR 513.36 - Government contractors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Government contractors. 513.36 Section 513.36 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Release of Information General Provisions and Procedures § 513.36 Government...

28 CFR 513.36 - Government contractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Government contractors. 513.36 Section 513.36 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Release of Information General Provisions and Procedures § 513.36 Government...

78 FR 1256 - Guam Military Base Realignment Contractor Recruitment Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Contractor Recruitment Standards AGENCY: Employment and Training Administration, Labor. ACTION: Final notice... issuing this notice to announce recruitment standards that construction contractors are required to follow... B) by adding a new subsection (6). This provision prohibits contractors engaged in construction...

77 FR 3503 - Guam Military Base Realignment Contractor Recruitment Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-24

... Contractor Recruitment Standards AGENCY: Employment and Training Administration, Labor. ACTION: Notice... issuing this notice to announce the recruitment standards that construction contractors are required to... contractors engaged in construction projects related to the realignment of U.S. military forces from Okinawa...

14 CFR 1274.402 - Contractor acquired property.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Contractor acquired property. 1274.402 Section 1274.402 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Property § 1274.402 Contractor acquired property. As provided in § 1274.923...

28 CFR 115.77 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... volunteers. 115.77 Section 115.77 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.177 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... volunteers. 115.177 Section 115.177 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be prohibited... violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.177 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... volunteers. 115.177 Section 115.177 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be prohibited... violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.77 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... volunteers. 115.77 Section 115.77 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.77 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... volunteers. 115.77 Section 115.77 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.177 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... volunteers. 115.177 Section 115.177 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be prohibited... violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

48 CFR 2804.470 - Contractor Personnel Security Program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor Personnel Security Program. 2804.470 Section 2804.470 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General ADMINISTRATIVE MATTERS Safeguarding Classified Information Within Industry 2804.470 Contractor...

28 CFR 115.377 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... volunteers. 115.377 Section 115.377 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... any other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.377 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... volunteers. 115.377 Section 115.377 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... any other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

28 CFR 115.377 - Corrective action for contractors and volunteers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... volunteers. 115.377 Section 115.377 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... for contractors and volunteers. (a) Any contractor or volunteer who engages in sexual abuse shall be... any other violation of agency sexual abuse or sexual harassment policies by a contractor or volunteer. ...

21 CFR 21.30 - Records of contractors.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Administration by individuals or organizations whose primary function is delivery of health services, such as... contractors to accomplish Food and Drug Administration functions, from which information is retrieved by... is considered to accomplish a Food and Drug Administration function if the proposal or activity it...

21 CFR 21.30 - Records of contractors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Administration by individuals or organizations whose primary function is delivery of health services, such as... contractors to accomplish Food and Drug Administration functions, from which information is retrieved by... is considered to accomplish a Food and Drug Administration function if the proposal or activity it...

21 CFR 21.30 - Records of contractors.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Administration by individuals or organizations whose primary function is delivery of health services, such as... contractors to accomplish Food and Drug Administration functions, from which information is retrieved by... is considered to accomplish a Food and Drug Administration function if the proposal or activity it...

21 CFR 21.30 - Records of contractors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Administration by individuals or organizations whose primary function is delivery of health services, such as... contractors to accomplish Food and Drug Administration functions, from which information is retrieved by... is considered to accomplish a Food and Drug Administration function if the proposal or activity it...

Management and operating contractors' pension plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1987-06-01

This report concerns the management of 28 M and O contractor pension plans with assets exceeding $2.6 billion in 1983. At the end of 1983, these pension plans were overfunded by $600 million. The Department could have saved $94 million in 1983 had the contractors been required to limit their pension plan contributions to the Government-established minimum level. Since 1979, the Department has continually reimbursed these contractors for contributions to pension plans that were already overfunded and we estimate that these plans are currently overfunded in excess of $1 billion. Additional annual savings of about $548,000 could be realized ifmore » the Department obtained waivers for M and O contractors participating in the Pension Benefit Guaranty Corporation's (PBGC) insurance program. Management and Administration, which has overall responsibility for controlling such costs, indicated it did not agree that contractors should fund pension plans at only the minimum required level. General agreement was indicated with the need to obtain waivers from PBGC premiums and better protect the Department's interest in contractor excess pension assets.« less

EISCAT observations during MAC/SINE and MAC/Epsilon

NASA Technical Reports Server (NTRS)

Roettger, J.; Hoppe, U.-P.; Hall, C.

1989-01-01

The EISCAT incoherent scatter radar facility in Tromsoe, Norway was operated during the MAC/SINE campaign for 78 hours in the period 10 June to 17 July 1987, and during the MAC/Epsilon campaign for 90 hours in the period 15 October to 5 November 1987. The VHF (224 MHz) radar operations during MAC/SINE yielded most interesting observations of strong coherent echoes from the mesopause region. Characteristic data of these polar mesospheric summer echoes are presented. The UHF (933 MHz) radar operations during MAC/Epsilon were done with 18 deg off zenith beam and allows the deduction of meridonal and horizontal wind components as well as radial velocity spectra in addition to the usual electron density profiles in the D and lower E regions. Some results from the VHF and UHF radars indicating the presence of gravity waves are examined.

77 FR 69715 - Federal Acquisition Regulation; Updates to Contract Reporting and Central Contractor Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... Contractor Registration AGENCY: Department of Defense (DoD), General Services Administration (GSA), and... changes the clauses requiring contractor registration in the Central Contractor Registration (CCR... unique identifier for contractors. It is used (1) to uniquely identify a contractor entity, and (2) to...

48 CFR 642.1503-70 - Contractor Performance System (CPS).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contractor Performance System (CPS). 642.1503-70 Section 642.1503-70 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 642.1503...

77 FR 52107 - Air Traffic Data in the Possession of Government Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

... Government Contractors AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice. SUMMARY: The... possession of government contractors providing operational services to the FAA. This notice specifies how and... contractors. SUPPLEMENTARY INFORMATION: A. Background On August 3, 2012, the Pilot's Bill of Rights, Public...

48 CFR 252.244-7001 - Contractor purchasing system administration.

Code of Federal Regulations, 2014 CFR

2014-10-01

....246-7007, Contractor Counterfeit Electronic Part Detection and Avoidance System, if applicable; (20... Defense to rely upon information produced by the system that is needed for management purposes. (b... Counterfeit Electronic Part Detection and Avoidance System; (2) Provide for an organizational and...

Analysis of Criteria Influencing Contractor Selection Using TOPSIS Method

NASA Astrophysics Data System (ADS)

Alptekin, Orkun; Alptekin, Nesrin

2017-10-01

Selection of the most suitable contractor is an important process in public construction projects. This process is a major decision which may influence the progress and success of a construction project. Improper selection of contractors may lead to problems such as bad quality of work and delay in project duration. Especially in the construction projects of public buildings, the proper choice of contractor is beneficial to the public institution. Public procurement processes have different characteristics in respect to dissimilarities in political, social and economic features of every country. In Turkey, Turkish Public Procurement Law PPL 4734 is the main regulatory law for the procurement of the public buildings. According to the PPL 4734, public construction administrators have to contract with the lowest bidder who has the minimum requirements according to the criteria in prequalification process. Public administrators are not sufficient for selection of the proper contractor because of the restrictive provisions of the PPL 4734. The lowest bid method does not enable public construction administrators to select the most qualified contractor and they have realised the fact that the selection of a contractor based on lowest bid alone is inadequate and may lead to the failure of the project in terms of time delay Eand poor quality standards. In order to evaluate the overall efficiency of a project, it is necessary to identify selection criteria. This study aims to focus on identify importance of other criteria besides lowest bid criterion in contractor selection process of PPL 4734. In this study, a survey was conducted to staff of Department of Construction Works of Eskisehir Osmangazi University. According to TOPSIS (Technique for Order Preference by Similarity to the Ideal Solution) for analysis results, termination of construction work in previous tenders is the most important criterion of 12 determined criteria. The lowest bid criterion is ranked in rank 5.

49 CFR 199.115 - Contractor employees.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Drug Testing... contractor, an operator may provide by contract that the drug testing, education, and training required by...

49 CFR 199.115 - Contractor employees.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Drug Testing... contractor, an operator may provide by contract that the drug testing, education, and training required by...

49 CFR 199.115 - Contractor employees.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Drug Testing... contractor, an operator may provide by contract that the drug testing, education, and training required by...

49 CFR 199.115 - Contractor employees.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Drug Testing... contractor, an operator may provide by contract that the drug testing, education, and training required by...

Configuration Management Plan for the Tank Farm Contractor

DOE Office of Scientific and Technical Information (OSTI.GOV)

WEIR, W.R.

The Configuration Management Plan for the Tank Farm Contractor describes configuration management the contractor uses to manage and integrate its technical baseline with the programmatic and functional operations to perform work. The Configuration Management Plan for the Tank Farm Contractor supports the management of the project baseline by providing the mechanisms to identify, document, and control the technical characteristics of the products, processes, and structures, systems, and components (SSC). This plan is one of the tools used to identify and provide controls for the technical baseline of the Tank Farm Contractor (TFC). The configuration management plan is listed in themore » management process documents for TFC as depicted in Attachment 1, TFC Document Structure. The configuration management plan is an integrated approach for control of technical, schedule, cost, and administrative processes necessary to manage the mission of the TFC. Configuration management encompasses the five functional elements of: (1) configuration management administration, (2) configuration identification, (3) configuration status accounting, (4) change control, and (5 ) configuration management assessments.« less

Profile of a leader. Alena Jean MacMaster: administrator, educator, professional activist and community advocate.

PubMed

Gautreau, G; Winans, P

1999-01-01

This paper profiles Alena Jean MacMaster, an extraordinary nurse leader, activist, visionary and humanitarian from New Brunswick. Her determination and drive were instrumental in fostering the development and progression of health care, nursing education and nursing services at the local, provincial, federal and international levels. "First, loyalty to the institution in which you serve. The patient is the most important person in the entire institution," was Miss MacMaster's guiding principle throughout her career.

Refractory inclusions from the ungrouped carbonaceous chondrites MAC 87300 and MAC 88107

NASA Astrophysics Data System (ADS)

Russell, Sara S.; Davis, Andrew M.; MacPherson, Glenn J.; Guan, Yunbin; Huss, Gary R.

2000-09-01

MAC 87300 and MAC 88107 are two unusual carbonaceous chondrites that are intermediate in chemical composition between the CO3 and CM2 meteorite groups. Calcium-aluminum-rich inclusions (CAIs) from these two meteorites are mostly spinel-pyroxene and melilite-rich (Type A) varieties. Spinel-pyroxene inclusions have either a banded or nodular texture, with aluminous diopside rimming iron-poor spinel. Melilite-rich inclusions (4-42) are irregular in shape and contain minor spinel (FeO <1 wt%), perovskite and, more rarely, hibonite. The CAIs in MAC 88107 and MAC 87300 are similar in primary mineralogy to CAIs from low petrologic grade CO3 meteorites, but differ in that they commonly contain phyllosilicates. The two meteorites also differ somewhat from each other: melilite is more abundant and slightly more aluminum-rich in inclusions from MAC 88107 than in those from MAC 87300, and phyllosilicate is more abundant and magnesium-poor in MAC 87300 CAIs relative to that in MAC 88107. These differences suggest that the two meteorites are not paired. CAI sizes and the abundance of melilite-rich CAIs in MAC 88107 and MAC 87300 suggests a genetic relationship to CO3 meteorites, but the CAIs in both have suffered a greater degree of aqueous alteration than is observed in COs. Al-rich melilite in CAIs from both meteorites generally contains excess 26Mg, presumably from the in situ decay of 26Al. Although well-defined isochrons are not observed, the 26Mg excesses are consistent with initial 26Al/27Al ~3-5 ( 10-5. An unusual hibonite-bearing inclusion is isotopically heterogeneous, with two large and abutting hibonite crystals showing significant differences in their degrees of mass-dependent fractionation of 25Mg/24Mg. The two crystals also show differences in their inferred initial 26Al/27Al, 1 ( 10-5 vs. 3 ( 10-6.

Design and FPGA implementation for MAC layer of Ethernet PON

NASA Astrophysics Data System (ADS)

Zhu, Zengxi; Lin, Rujian; Chen, Jian; Ye, Jiajun; Chen, Xinqiao

2004-04-01

Ethernet passive optical network (EPON), which represents the convergence of low-cost, high-bandwidth and supporting multiple services, appears to be one of the best candidates for the next-generation access network. The work of standardizing EPON as a solution for access network is still underway in the IEEE802.3ah Ethernet in the first mile (EFM) task force. The final release is expected in 2004. Up to now, there has been no standard application specific integrated circuit (ASIC) chip available which fulfills the functions of media access control (MAC) layer of EPON. The MAC layer in EPON system has many functions, such as point-to-point emulation (P2PE), Ethernet MAC functionality, multi-point control protocol (MPCP), network operation, administration and maintenance (OAM) and link security. To implement those functions mentioned above, an embedded real-time operating system (RTOS) and a flexible programmable logic device (PLD) with an embedded processor are used. The software and hardware functions in MAC layer are realized through programming embedded microprocessor and field programmable gate array(FPGA). Finally, some experimental results are given in this paper. The method stated here can provide a valuable reference for developing EPON MAC layer ASIC.

TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks

USGS Publications Warehouse

Song, W.-Z.; Huang, R.; Shirazi, B.; LaHusen, R.

2009-01-01

Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and each frame into slots. A parent node determines the children's frame assignment based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. First, given any node, at any time slot, there is at most one active sender in its neighborhood (including itself). Second, the packet scheduling with TreeMAC is bufferless, which therefore minimizes the probability of network congestion. Third, the data throughput to the gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24-node testbed show that TreeMAC protocol significantly improves network throughput, fairness, and energy efficiency compared to TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC. Partial results of this paper were published in Song, Huang, Shirazi and Lahusen [W.-Z. Song, R. Huang, B. Shirazi, and R. Lahusen, TreeMAC: Localized TDMA MAC protocol for high-throughput and fairness in sensor networks, in: The 7th Annual IEEE International Conference on Pervasive Computing and Communications, PerCom, March 2009]. Our new contributions include analyses of the performance of TreeMAC from various aspects. We also present more implementation detail and evaluate TreeMAC from other aspects. ?? 2009 Elsevier B.V.

32 CFR 806b.6 - Systems of records operated by a contractor.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Systems of records operated by a contractor... ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.6 Systems of records operated by a contractor. Contractors who are required to operate or maintain a Privacy Act system of records by contract...

32 CFR 806b.6 - Systems of records operated by a contractor.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Systems of records operated by a contractor... ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.6 Systems of records operated by a contractor. Contractors who are required to operate or maintain a Privacy Act system of records by contract...

32 CFR 806b.6 - Systems of records operated by a contractor.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Systems of records operated by a contractor... ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.6 Systems of records operated by a contractor. Contractors who are required to operate or maintain a Privacy Act system of records by contract...

32 CFR 806b.6 - Systems of records operated by a contractor.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Systems of records operated by a contractor... ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.6 Systems of records operated by a contractor. Contractors who are required to operate or maintain a Privacy Act system of records by contract...

32 CFR 806b.6 - Systems of records operated by a contractor.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Systems of records operated by a contractor... ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.6 Systems of records operated by a contractor. Contractors who are required to operate or maintain a Privacy Act system of records by contract...

I-MAC: an incorporation MAC for wireless sensor networks

NASA Astrophysics Data System (ADS)

Zhao, Jumin; Li, Yikun; Li, Dengao; Lin, Xiaojie

2017-11-01

This paper proposes an innovative MAC protocol called I-MAC. Protocol for wireless sensor networks, which combines the advantages of collision tolerance and collision cancellation. The protocol increases the number of antenna in wireless sensor nodes. The purpose is to monitor the occurrence of packet collisions by increasing the number of antenna in real time. The built-in identity structure is used in the frame structure in order to help the sending node to identify the location of the receiving node after a data packet collision is detected. Packets can be recovered from where the conflict occurred. In this way, we can monitor the conflict for a fixed period of time. It can improve the channel utilisation through changing the transmission probability of collision nodes and solve the problem of hidden terminal through collision feedback mechanism. We have evaluated our protocol. Our results show that the throughput of I-MAC is 5 percentage points higher than that of carrier sense multiple access/collision notification. The network utilisation of I-MAC is more than 92%.

TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks

USGS Publications Warehouse

Song, W.-Z.; Huang, R.; Shirazi, B.; Husent, R.L.

2009-01-01

Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and frame into slots. Parent determines children's frame assigmnent based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. Firstly, given any node, at any time slot, there is at most one active sender in its neighborhood (includ ing itself). Secondly, the packet scheduling with TreelMAC is bufferless, which therefore minimizes the probability of network congestion. Thirdly, the data throughput to gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24 node test bed demonstrate that TreeMAC protocol significantly improves network throughput and energy efficiency, by comparing to the TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC[8]. ?? 2009 IEEE.

Contractor evaluations in the contractor selection process.

DOT National Transportation Integrated Search

2014-04-01

The current contractor evaluation system in use within the Kentucky Transportation Cabinet is based on the contractor evaluation system developed as part of SPR 212-00 "Quality Based Prequalification of Contractors." This system relies on average per...

28 CFR 115.32 - Volunteer and contractor training.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Volunteer and contractor training. 115.32 Section 115.32 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Training and Education § 115.32 Volunteer and...

75 FR 22810 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

...)/Medicare Administrative Contractor (MAC) through the Medicare cost report (MCR). The primary function of... function; (2) the accuracy of the estimated burden; (3) ways to enhance the quality, utility, and clarity...

75 FR 10267 - Federal Acquisition Regulation; Submission for OMB Review; Contractor Use of Interagency Motor...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-05

... ADMINISTRATION [OMB Control No. 9000-0032] Federal Acquisition Regulation; Submission for OMB Review; Contractor... previously approved information collection requirement concerning contractor use of interagency motor pool... contracting officer may authorize cost-reimbursement contractors to obtain, for official purposes only...

Introduction to MAC CRM training

NASA Technical Reports Server (NTRS)

Brown, Donald D.

1987-01-01

The author introduces the Military Airlift Command (MAC) and its mission. A brief history of Cockpit Resource Management (CRM) as it relates to MAC is given. He also states why MAC is currently interested in CRM.

PAD-MAC: Primary User Activity-Aware Distributed MAC for Multi-Channel Cognitive Radio Networks

PubMed Central

Ali, Amjad; Piran, Md. Jalil; Kim, Hansoo; Yun, Jihyeok; Suh, Doug Young

2015-01-01

Cognitive radio (CR) has emerged as a promising technology to solve problems related to spectrum scarcity and provides a ubiquitous wireless access environment. CR-enabled secondary users (SUs) exploit spectrum white spaces opportunistically and immediately vacate the acquired licensed channels as primary users (PUs) arrive. Accessing the licensed channels without the prior knowledge of PU traffic patterns causes severe throughput degradation due to excessive channel switching and PU-to-SU collisions. Therefore, it is significantly important to design a PU activity-aware medium access control (MAC) protocol for cognitive radio networks (CRNs). In this paper, we first propose a licensed channel usage pattern identification scheme, based on a two-state Markov model, and then estimate the future idle slots using previous observations of the channels. Furthermore, based on these past observations, we compute the rank of each available licensed channel that gives SU transmission success assessment during the estimated idle slot. Secondly, we propose a PU activity-aware distributed MAC (PAD-MAC) protocol for heterogeneous multi-channel CRNs that selects the best channel for each SU to enhance its throughput. PAD-MAC controls SU activities by allowing them to exploit the licensed channels only for the duration of estimated idle slots and enables predictive and fast channel switching. To evaluate the performance of the proposed PAD-MAC, we compare it with the distributed QoS-aware MAC (QC-MAC) and listen-before-talk MAC schemes. Extensive numerical results show the significant improvements of the PAD-MAC in terms of the SU throughput, SU channel switching rate and PU-to-SU collision rate. PMID:25831084

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter.

PubMed

Modali, Sita D; Zgurskaya, Helen I

2011-08-01

Escherichia coli MacAB-TolC is a tripartite macrolide efflux transporter driven by hydrolysis of ATP. In this complex, MacA is the periplasmic membrane fusion protein that stimulates the activity of MacB transporter and establishes the link with the outer membrane channel TolC. The molecular mechanism by which MacA stimulates MacB remains unknown. Here, we report that the periplasmic membrane proximal domain of MacA plays a critical role in functional MacA-MacB interactions and stimulation of MacB ATPase activity. Binding of MacA to MacB stabilizes the ATP-bound conformation of MacB, whereas interactions with both MacB and TolC affect the conformation of MacA. A single G353A substitution in the C-terminus of MacA inactivates MacAB-TolC function by changing the conformation of the membrane proximal domain of MacA and disrupting the proper assembly of the MacA-MacB complex. We propose that MacA acts in transport by promoting MacB transition into the closed ATP-bound conformation and in this respect, is similar to the periplasmic solute-binding proteins. © 2011 Blackwell Publishing Ltd.

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter

PubMed Central

Modali, Sita D.; Zgurskaya, Helen I.

2011-01-01

Escherichia coli MacAB-TolC is a tri-partite macrolide efflux transporter driven by hydrolysis of ATP. In this complex, MacA is the periplasmic membrane fusion protein that stimulates the activity of MacB transporter and establishes the link with the outer membrane channel TolC. The molecular mechanism by which MacA stimulates MacB remains unknown. Here, we report that the periplasmic membrane proximal domain of MacA plays a critical role in functional MacA-MacB interactions and stimulation of MacB ATPase activity. Binding of MacA to MacB stabilizes the ATP-bound conformation of MacB, whereas interactions with both MacB and TolC affect the conformation of MacA. A single G353A substitution in the C-terminus of MacA inactivates MacAB-TolC function by changing the conformation of the membrane proximal domain of MacA and disrupting the proper assembly of the MacA-MacB complex. We propose that MacA acts in transport by promoting MacB transition into the closed ATP-bound conformation and in this respect, is similar to the periplasmic solute-binding proteins. PMID:21696464

75 FR 38683 - Federal Acquisition Regulation; FAR Case 2008-035, Registry of Disaster Response Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... Response Contractors AGENCIES: Department of Defense (DoD), General Services Administration (GSA), and... of a registry of disaster response contractors. DATES: Effective Date: August 2, 2010. FOR FURTHER..., requires the establishment and maintenance of a registry of contractors willing to perform debris removal...

48 CFR 2945.104 - Review and correction of contractors' property control systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Review and correction of contractors' property control systems. 2945.104 Section 2945.104 Federal Acquisition Regulations System... contractors' property control systems. When the Government's property administrator determines that review and...

48 CFR 2945.104 - Review and correction of contractors' property control systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Review and correction of contractors' property control systems. 2945.104 Section 2945.104 Federal Acquisition Regulations System... contractors' property control systems. When the Government's property administrator determines that review and...

48 CFR 2945.104 - Review and correction of contractors' property control systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Review and correction of contractors' property control systems. 2945.104 Section 2945.104 Federal Acquisition Regulations System... contractors' property control systems. When the Government's property administrator determines that review and...

48 CFR 2945.104 - Review and correction of contractors' property control systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Review and correction of contractors' property control systems. 2945.104 Section 2945.104 Federal Acquisition Regulations System... contractors' property control systems. When the Government's property administrator determines that review and...

The contractor`s role in low-level waste disposal facility application review and licensing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Serie, P.J.; Dressen, A.L.

1991-12-31

The California Department of Health Services will soon reach a licensing decision on the proposed Ward Valley low-level radioactive waste disposal facility. As the first regulatory agency in the country to address the 10 CFR Part 61 requirements for a new disposal facility, California`s program has broken new ground in its approach. Throughout the review process, the Department has relied on contractor support to augment its technical and administrative staff. A team consisting of Roy F. Weston, Inc., supported by ERM-Program Management Corp., Environmental Issues Management, Inc., and Rogers and Associates Engineering Corporation, has worked closely with the Department inmore » a staff extension role. The authors have been involved with the project in contractor project management roles since 1987, and continue to support the Department`s program as it proceeds to finalize its licensing process. This paper describes the selection process used to identify a contractor team with the needed skills and experience, and the makeup of team capabilities. It outlines the management, communication, and technical approaches used to assure a smooth agency-contractor function and relationship. It describes the techniques used to ensure that decisions and documents represented the Department credibly in its role as the regulatory and licensing agency under the Nuclear Regulatory Commission (NRC) Agreement State program. The paper outlines the license application review process and activities, through preparation of licensing documentation and responses to public comments. Lessons learned in coordination of an agency-contractor team effort to review and license a low-level waste disposal facility are reviewed and suggestions made for approaching a similar license application review and licensing situation.« less

Government - contractor interaction

NASA Technical Reports Server (NTRS)

Thomas, D. M.

1983-01-01

The development of the Administrative Contracting Officer represents an advance in the Government system of contract management because it provides an individual with knowledge, time, and a specialized function to insure performance of Government contracts. However, the development has created a dichotomy between the award and the post-award function which increases the adversary relationship with Government contractors. This paper advocates that this adversary relationship can be decreased if PCOs and ACOs are provided with opportunities to serve in the assignments of the other.

The effect of nitrous oxide on the minimum alveolar concentration (MAC) and MAC derivatives of isoflurane in dogs

PubMed Central

Voulgaris, Debra A.; Egger, Christine M.; Seddighi, M. Reza; Rohrbach, Barton W.; Love, Lydia C.; Doherty, Thomas J.

2013-01-01

This study investigated the effects of 70% nitrous oxide (N2O) on the minimum alveolar concentration (MAC) of isoflurane (ISO) that prevents purposeful movement, the MAC of ISO at which there is no motor movement (MACNM), and the MAC of ISO at which autonomic responses are blocked (MACBAR) in dogs. Six adult, healthy, mixed-breed, intact male dogs were anesthetized with ISO delivered via mask. Baseline MAC, MACNM, and MACBAR of ISO were determined for each dog using a supra-maximal electrical stimulus (50 V, 50 Hz, 10 ms). Nitrous oxide (70%) was then administered and MAC and its derivatives (N2O-MAC, N2O-MACNM, and N2O-MACBAR) were determined using the same methodology. The values for baseline MAC, MACNM, and MACBAR were 1.39 ± 0.14, 1.59 ± 0.10, and 1.72 ± 0.16, respectively. The addition of 70% N2O decreased MAC, MACNM, and MACBAR by 32%, 15%, and 25%, respectively. PMID:24082405

41 CFR 109-1.5113 - Loss, damage, or destruction of personal property in possession of designated contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... designated contractors. (a) Designated contractors shall report any loss, damage, or destruction of personal... administrator; or loss, damage, or destruction of personal property not previously reported by the contractor... written reports. (c) Reports of physical inventory results and identified discrepancies shall be submitted...

41 CFR 109-1.5113 - Loss, damage, or destruction of personal property in possession of designated contractors.

Code of Federal Regulations, 2011 CFR

2011-01-01

... designated contractors. (a) Designated contractors shall report any loss, damage, or destruction of personal... administrator; or loss, damage, or destruction of personal property not previously reported by the contractor... written reports. (c) Reports of physical inventory results and identified discrepancies shall be submitted...

SACRB-MAC: A High-Capacity MAC Protocol for Cognitive Radio Sensor Networks in Smart Grid

PubMed Central

Yang, Zhutian; Shi, Zhenguo; Jin, Chunlin

2016-01-01

The Cognitive Radio Sensor Network (CRSN) is considered as a viable solution to enhance various aspects of the electric power grid and to realize a smart grid. However, several challenges for CRSNs are generated due to the harsh wireless environment in a smart grid. As a result, throughput and reliability become critical issues. On the other hand, the spectrum aggregation technique is expected to play an important role in CRSNs in a smart grid. By using spectrum aggregation, the throughput of CRSNs can be improved efficiently, so as to address the unique challenges of CRSNs in a smart grid. In this regard, we proposed Spectrum Aggregation Cognitive Receiver-Based MAC (SACRB-MAC), which employs the spectrum aggregation technique to improve the throughput performance of CRSNs in a smart grid. Moreover, SACRB-MAC is a receiver-based MAC protocol, which can provide a good reliability performance. Analytical and simulation results demonstrate that SACRB-MAC is a promising solution for CRSNs in a smart grid. PMID:27043573

SACRB-MAC: A High-Capacity MAC Protocol for Cognitive Radio Sensor Networks in Smart Grid.

PubMed

Yang, Zhutian; Shi, Zhenguo; Jin, Chunlin

2016-03-31

The Cognitive Radio Sensor Network (CRSN) is considered as a viable solution to enhance various aspects of the electric power grid and to realize a smart grid. However, several challenges for CRSNs are generated due to the harsh wireless environment in a smart grid. As a result, throughput and reliability become critical issues. On the other hand, the spectrum aggregation technique is expected to play an important role in CRSNs in a smart grid. By using spectrum aggregation, the throughput of CRSNs can be improved efficiently, so as to address the unique challenges of CRSNs in a smart grid. In this regard, we proposed Spectrum Aggregation Cognitive Receiver-Based MAC (SACRB-MAC), which employs the spectrum aggregation technique to improve the throughput performance of CRSNs in a smart grid. Moreover, SACRB-MAC is a receiver-based MAC protocol, which can provide a good reliability performance. Analytical and simulation results demonstrate that SACRB-MAC is a promising solution for CRSNs in a smart grid.

MQ-MAC: A Multi-Constrained QoS-Aware Duty Cycle MAC for Heterogeneous Traffic in Wireless Sensor Networks

PubMed Central

Monowar, Muhammad Mostafa; Rahman, Md. Obaidur; Hong, Choong Seon; Lee, Sungwon

2010-01-01

Energy conservation is one of the striking research issues now-a-days for power constrained wireless sensor networks (WSNs) and hence, several duty-cycle based MAC protocols have been devised for WSNs in the last few years. However, assimilation of diverse applications with different QoS requirements (i.e., delay and reliability) within the same network also necessitates in devising a generic duty-cycle based MAC protocol that can achieve both the delay and reliability guarantee, termed as multi-constrained QoS, while preserving the energy efficiency. To address this, in this paper, we propose a Multi-constrained QoS-aware duty-cycle MAC for heterogeneous traffic in WSNs (MQ-MAC). MQ-MAC classifies the traffic based on their multi-constrained QoS demands. Through extensive simulation using ns-2 we evaluate the performance of MQ-MAC. MQ-MAC provides the desired delay and reliability guarantee according to the nature of the traffic classes as well as achieves energy efficiency. PMID:22163439

Roderick MacKinnon - Patents

Science.gov Websites

CHANNEL PROTEINS, MUTANT PROKARYOTIC CATION CHANNEL PROTEINS, AND USES THEREOF - MacKinnon, Roderick cation channel proteins, and potentially have uses in treating conditions related to the function of SENSOR DOMAINS OF VOLTAGE-DEPENDENT ION CHANNEL PROTEINS AND USES THEREOF - MacKinnon, Roderick; et. al

AeroMACS System Characterization and Demonstrations

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Apaza, Rafael D.; Dimond, Robert P.

2013-01-01

This The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past 3 years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

AeroMACS System Characterization and Demonstrations

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Apaza, Rafael D.; Dimond, Robert P.

2013-01-01

The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past three years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

AeroMACS system characterization and demonstrations

NASA Astrophysics Data System (ADS)

Kerczewski, R. J.; Apaza, R. D.; Dimond, R. P.

This The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past three years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

User's manual for MacPASCO

NASA Technical Reports Server (NTRS)

Lucas, S. H.; Davis, R. C.

1992-01-01

A user's manual is presented for MacPASCO, which is an interactive, graphic, preprocessor for panel design. MacPASCO creates input for PASCO, an existing computer code for structural analysis and sizing of longitudinally stiffened composite panels. MacPASCO provides a graphical user interface which simplifies the specification of panel geometry and reduces user input errors. The user draws the initial structural geometry and reduces user input errors. The user draws the initial structural geometry on the computer screen, then uses a combination of graphic and text inputs to: refine the structural geometry; specify information required for analysis such as panel load and boundary conditions; and define design variables and constraints for minimum mass optimization. Only the use of MacPASCO is described, since the use of PASCO has been documented elsewhere.

48 CFR 245.105 - Contractor's property management system compliance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... management system compliance. 245.105 Section 245.105 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 245.105 Contractor's property management system compliance. The assigned property administrator shall perform...

Performance-Based Contractor Prequalification as an Alternative to Performance Bonds

DOT National Transportation Integrated Search

2014-08-01

State departments of transportation rely on private industry construction contractors to build, rehabilitate, and replace their infrastructure assets. The Federal Highway Administration (FHWA) is interested in providing guidance that State transporta...

MAC-sparing effect of nitrous oxide in sevoflurane anesthetized sheep and its reversal with systemic atipamezole administration

PubMed Central

Scanu, Antonio; Melosu, Valentino; Careddu, Giovanni Mario; Sotgiu, Giovanni

2018-01-01

Introduction Nitrous oxide (N2O) is an anesthetic gas with antinociceptive properties and reduces the minimum alveolar concentration (MAC) for volatile anesthetic agents, potentially through mechanisms involving central alpha2-adrenoceptors. We hypothesized that 70% N2O in the inspired gas will significantly reduce the MAC of sevoflurane (MACSEVO) in sheep, and that this effect can be reversed by systemic atipamezole. Materials and methods Animals were initially anesthetized with SEVO in oxygen (O2) and exposed to an electrical current as supramaximal noxious stimulus in order to determine MACSEVO (in duplicates). Thereafter, 70% N2O was added to the inspired gas and the MAC re-determined in the presence of N2O (MACSN). A subgroup of sheep were anesthetized a second time with SEVO/N2O for re-determination of MACSN, after which atipamezole (0.2 mg kg-1, IV) was administered for MACSNA determinations. Sheep were anesthetized a third time, initially with only SEVO/O2 to re-determine MACSEVO, after which atipamezole (0.2 mg kg-1, IV) was administered for determination of MACSA. Results MACSEVO was 2.7 (0.3)% [mean (standard deviation)]. Addition of N2O resulted in a 37% reduction of MACSEVO to MACSN of 1.7 (0.2)% (p <0.0001). Atipamezole reversed this effect, producing a MACSNA of 3.1 (0.7)%, which did not differ from MACSEVO (p = 0.12). MACSEVO did not differ from MACSA (p = 0.69). Cardiorespiratory variables were not different among experimental groups except a lower ETCO2 in animals exposed to SEVO/N2O. Conclusions N2O produces significant MACSEVO-reduction in sheep; this effect is completely reversed by IV atipamezole confirming the involvement of alpha2-adrenoreceptors in the MAC-sparing action of N2O. PMID:29315308

76 FR 71797 - Federal Agricultural Mortgage Corporation Funding and Fiscal Affairs; Farmer Mac Investments and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-18

...The Farm Credit Administration (FCA, Agency, us, or we) proposes to amend our regulations governing the Federal Agricultural Mortgage Corporation (Farmer Mac or the Corporation) in the areas of non-program investments and liquidity. We are proposing to modify the specific requirements supporting our objective to ensure that Farmer Mac maintains adequate liquidity to withstand stressful conditions in accordance with board-established risk tolerance and holds only high- quality, liquid investments in its liquidity reserve. We also propose to expand the allowable purposes of Farmer Mac's non-program investments to include investments that would add value to Farmer Mac's operations by complementing its program activities. Further, we request comments on the best approach for compliance with section 939A of the Dodd-Frank Wall Street Reform and Consumer Protection Act (Dodd-Frank Act or DFA), which requires us to remove all references to and requirements relating to credit ratings and to substitute other appropriate standards of creditworthiness. Finally, we propose significant reorganizing of sections to make the flow of the issues covered more logical.

Report on audit of Department of Energy`s contractor salary increase fund

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-04-04

The Department of Energy (Department) uses contractors to operate its facilities and compensates contractor employees based on their skills, complexity of jobs, and work performance. Thirty-one of the Department`s major contractors reported a total payroll of $4.3 billion and $4.4 billion during 1994 and 1995, respectively. The 31 contractors also reported awarding salary increases of $18 million for 1994 and $200 million for 1995. The purpose of the audit was to review the process used to determine and approve the amount of salary increases for contractor employees. The specific audit objective was to determine whether salary increases received by contractormore » employees were in accordance with Departmental policies and procedures. The Department of Energy Acquisition Regulation (DEAR) requires that contractor salary actions be within specific limitations, supportable, and approved prior to incurrence of costs. In addition, the Secretary of Energy imposed a 1 year salary freeze on the merit portion of management and operating contractor employee salaries for each contractor`s Fiscal Year 1994 compensation year. However, a fund for promotions and adjustments was approved but limited to 0.5 percent of payroll for the year. A review of eight major contractors showed that six complied with the Department`s policies on salary increases. The other two gave salary increases that were not always in accordance with Departmental policies. This resulted in both contractors not fully complying with the pay freeze in 1994 and exceeding their salary increase fund budgets in 1995. If these two contractors had implemented Department and contract requirements and contracting officers had properly performed their contract administrative responsibilities concerning salary increase funds, both contractors would have frozen salary increases and would not have exceeded their annual budgets.« less

W-MAC: A Workload-Aware MAC Protocol for Heterogeneous Convergecast in Wireless Sensor Networks

PubMed Central

Xia, Ming; Dong, Yabo; Lu, Dongming

2011-01-01

The power consumption and latency of existing MAC protocols for wireless sensor networks (WSNs) are high in heterogeneous convergecast, where each sensor node generates different amounts of data in one convergecast operation. To solve this problem, we present W-MAC, a workload-aware MAC protocol for heterogeneous convergecast in WSNs. A subtree-based iterative cascading scheduling mechanism and a workload-aware time slice allocation mechanism are proposed to minimize the power consumption of nodes, while offering a low data latency. In addition, an efficient schedule adjustment mechanism is provided for adapting to data traffic variation and network topology change. Analytical and simulation results show that the proposed protocol provides a significant energy saving and latency reduction in heterogeneous convergecast, and can effectively support data aggregation to further improve the performance. PMID:22163753

ZeroCal: Automatic MAC Protocol Calibration

NASA Astrophysics Data System (ADS)

Meier, Andreas; Woehrle, Matthias; Zimmerling, Marco; Thiele, Lothar

Sensor network MAC protocols are typically configured for an intended deployment scenario once and for all at compile time. This approach, however, leads to suboptimal performance if the network conditions deviate from the expectations. We present ZeroCal, a distributed algorithm that allows nodes to dynamically adapt to variations in traffic volume. Using ZeroCal, each node autonomously configures its MAC protocol at runtime, thereby trying to reduce the maximum energy consumption among all nodes. While the algorithm is readily usable for any asynchronous low-power listening or low-power probing protocol, we validate and demonstrate the effectiveness of ZeroCal on X-MAC. Extensive testbed experiments and simulations indicate that ZeroCal quickly adapts to traffic variations. We further show that ZeroCal extends network lifetime by 50% compared to an optimal configuration with identical and static MAC parameters at all nodes.

48 CFR 342.302 - Contract administration functions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MANAGEMENT CONTRACT ADMINISTRATION Contract Administration Office Functions 342.302 Contract administration..., contractor employees are considered “visitors.” Further, for any proposed or existing construction contract...

MacA, a periplasmic membrane fusion protein of the macrolide transporter MacAB-TolC, binds lipopolysaccharide core specifically and with high affinity.

PubMed

Lu, Shuo; Zgurskaya, Helen I

2013-11-01

The Escherichia coli MacAB-TolC transporter has been implicated in efflux of macrolide antibiotics and secretion of enterotoxin STII. In this study, we found that purified MacA, a periplasmic membrane fusion protein, contains one tightly bound rough core lipopolysaccharide (R-LPS) molecule per MacA molecule. R-LPS was bound specifically to MacA protein with affinity exceeding that of polymyxin B. Sequence analyses showed that MacA contains two high-density clusters of positively charged amino acid residues located in the cytoplasmic N-terminal domain and the periplasmic C-terminal domain. Substitutions in the C-terminal cluster reducing the positive-charge density completely abolished binding of R-LPS. At the same time, these substitutions significantly reduced the functionality of MacA in the protection of E. coli against macrolides in vivo and in the in vitro MacB ATPase stimulation assays. Taken together, our results suggest that R-LPS or a similar glycolipid is a physiological substrate of MacAB-TolC.

75 FR 6669 - Federal Acquisition Regulation; Submission for OMB Review; Contractors' Purchasing Systems Reviews

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

...' Purchasing Systems Reviews AGENCIES: Department of Defense (DOD), General Services Administration (GSA), and National Aeronautics and Space Administration (NASA). ACTION: Notice of request for public comments... collection requirement concerning contractors' purchasing systems reviews. A request for public comments was...

20 CFR 401.90 - Contractors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Contractors. 401.90 Section 401.90 Employees... Privacy Act § 401.90 Contractors. (a) All contracts which require a contractor to maintain, or on behalf... requiring the contractor to comply with the Privacy Act and this part. (b) A contractor and any employee of...

MAC reduction of isoflurane by sufentanil.

PubMed

Brunner, M D; Braithwaite, P; Jhaveri, R; McEwan, A I; Goodman, D K; Smith, L R; Glass, P S

1994-01-01

We have shown previously that a plasma fentanyl concentration of 1.67 ng ml-1 reduced the MAC of isoflurane by 50%. By comparing equal degrees of MAC reduction by sufentanil, we may determine the potency ratio of these opioids. Seventy-six patients were allocated randomly to receive predetermined infusions of sufentanil, and end-tidal concentrations of isoflurane in oxygen. Blood samples were obtained 10 min after the start of the infusion, and just before and after skin incision. Any purposeful movement by the patient was recorded. The MAC reduction of isoflurane produced by sufentanil was obtained using a logistic regression model. A sufentanil plasma concentration of 0.145 ng ml-1 (95% confidence limits 0.04, 0.26 ng ml-1) resulted in a 50% reduction in the MAC of isoflurane. At a plasma concentration greater than 0.5 ng ml-1, sufentanil exhibited a ceiling effect.

Performance-Based Contractor Prequalification as an Alternative to Performance Bonds [Tech Brief

DOT National Transportation Integrated Search

2014-01-01

State transportation departments must rely on private industry construction contractors to build, rehabilitate, and replace their infrastructure assets. The Federal Highway Administration (FHWA) is interested in ensuring that State transportation dep...

MacA, a Periplasmic Membrane Fusion Protein of the Macrolide Transporter MacAB-TolC, Binds Lipopolysaccharide Core Specifically and with High Affinity

PubMed Central

Lu, Shuo

2013-01-01

The Escherichia coli MacAB-TolC transporter has been implicated in efflux of macrolide antibiotics and secretion of enterotoxin STII. In this study, we found that purified MacA, a periplasmic membrane fusion protein, contains one tightly bound rough core lipopolysaccharide (R-LPS) molecule per MacA molecule. R-LPS was bound specifically to MacA protein with affinity exceeding that of polymyxin B. Sequence analyses showed that MacA contains two high-density clusters of positively charged amino acid residues located in the cytoplasmic N-terminal domain and the periplasmic C-terminal domain. Substitutions in the C-terminal cluster reducing the positive-charge density completely abolished binding of R-LPS. At the same time, these substitutions significantly reduced the functionality of MacA in the protection of E. coli against macrolides in vivo and in the in vitro MacB ATPase stimulation assays. Taken together, our results suggest that R-LPS or a similar glycolipid is a physiological substrate of MacAB-TolC. PMID:23974027

Defense Primer: DOD Contractors

DTIC Science & Technology

2017-02-10

contractors . A defense contractor , as defined by the Code of Federal Regulations, is “any individual, firm, corporation, partnership, association...158.3, “Definitions”). Within the defense policy community, the term contractor is commonly used in two different contexts. The word can describe

22 CFR 136.6 - Contractors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Contractors. 136.6 Section 136.6 Foreign... Contractors. To the extent that contractors enjoy importation or tax privileges in a foreign country because... provisions in their contracts that require the contractors to observe the requirements of these regulations...

MacIntyre, Rival Traditions and Education

ERIC Educational Resources Information Center

Stolz, Steven A.

2016-01-01

This paper critically discusses MacIntyre's thesis that education is essentially a contested concept. In order to contextualise my discussion, I discuss both whether rival educational traditions of education found in MacIntyre's work--which I refer to as instrumental and non-instrumental justifications of education--can be rationally resolved…

American Academy of Physical Medicine and Rehabilitation

MedlinePlus

... Inspector General DMEPOS, RACs, MACs, and other CMS contractor activity Research Advocacy State Affairs and Legislation Tracking ... Inspector General DMEPOS, RACs, MACs, and other CMS contractor activity Research Advocacy State Affairs and Legislation Tracking ...

Physiatrist: What Is a Physiatrist?

MedlinePlus

... Inspector General DMEPOS, RACs, MACs, and other CMS contractor activity Research Advocacy Academy Efforts Coalitions Position Statements ... Inspector General DMEPOS, RACs, MACs, and other CMS contractor activity Research Advocacy Academy Efforts Coalitions Position Statements ...

48 CFR 252.229-7004 - Status of contractors as a direct contractor (Spain).

Code of Federal Regulations, 2010 CFR

2010-10-01

..., development, maintenance, and operation of Spanish-American installations and facilities. (b) The Contractor... this contract by reference. (c) The Contractor shall apply to the appropriate Spanish authorities for approval of status as a Direct Contractor in order to complete duty-free import of non-Spanish equipment...

Aeronautical Mobile Airport Communications System (AeroMACS)

NASA Technical Reports Server (NTRS)

Budinger, James M.; Hall, Edward

2011-01-01

To help increase the capacity and efficiency of the nation s airports, a secure wideband wireless communications system is proposed for use on the airport surface. This paper provides an overview of the research and development process for the Aeronautical Mobile Airport Communications System (AeroMACS). AeroMACS is based on a specific commercial profile of the Institute of Electrical and Electronics Engineers (IEEE) 802.16 standard known as Wireless Worldwide Interoperability for Microwave Access or WiMAX (WiMax Forum). The paper includes background on the need for global interoperability in air/ground data communications, describes potential AeroMACS applications, addresses allocated frequency spectrum constraints, summarizes the international standardization process, and provides findings and recommendations from the world s first AeroMACS prototype implemented in Cleveland, Ohio, USA.

7 CFR 1788.12 - Contractors' bonds.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Contractors' bonds. 1788.12 Section 1788.12... Insurance for Contractors, Engineers, and Architects, Electric Borrowers § 1788.12 Contractors' bonds. Electric borrowers shall require contractors to obtain contractors' bonds when required by part 1726...

McMAC: Towards a MAC Protocol with Multi-Constrained QoS Provisioning for Diverse Traffic in Wireless Body Area Networks

PubMed Central

Monowar, Muhammad Mostafa; Hassan, Mohammad Mehedi; Bajaber, Fuad; Al-Hussein, Musaed; Alamri, Atif

2012-01-01

The emergence of heterogeneous applications with diverse requirements for resource-constrained Wireless Body Area Networks (WBANs) poses significant challenges for provisioning Quality of Service (QoS) with multi-constraints (delay and reliability) while preserving energy efficiency. To address such challenges, this paper proposes McMAC, a MAC protocol with multi-constrained QoS provisioning for diverse traffic classes in WBANs. McMAC classifies traffic based on their multi-constrained QoS demands and introduces a novel superframe structure based on the “transmit-whenever-appropriate” principle, which allows diverse periods for diverse traffic classes according to their respective QoS requirements. Furthermore, a novel emergency packet handling mechanism is proposed to ensure packet delivery with the least possible delay and the highest reliability. McMAC is also modeled analytically, and extensive simulations were performed to evaluate its performance. The results reveal that McMAC achieves the desired delay and reliability guarantee according to the requirements of a particular traffic class while achieving energy efficiency. PMID:23202224

Introduction to MacDraft. High-Technology Training Module.

ERIC Educational Resources Information Center

Traxler, Gene

This training module on MacDraft is part of a computer drafting skills unit on communications technology for grades 9-12. The objective is for each student to complete a drawing on the MacIntosh computer using the MacDraft software program. This drawing is to be dimensioned with a dual system and is to include a border and title block. This module…

Malcolm MacLachlan: International Humanitarian Award.

PubMed

2014-11-01

The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with under-served populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2014 recipient is Malcolm MacLachlan. "Focused on the rights and empowerment of vulnerable and marginalized groups, Malcolm MacLachlan's work synthesizes health, rehabilitation, and organizational and political psychology to promote social inclusion and global health." MacLachlan's award citation, biography, and selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC.

PubMed

Xu, Yongbin; Song, Saemee; Moeller, Arne; Kim, Nahee; Piao, Shunfu; Sim, Se-Hoon; Kang, Mooseok; Yu, Wookyung; Cho, Hyun-Soo; Chang, Iksoo; Lee, Kangseok; Ha, Nam-Chul

2011-04-15

Macrolide-specific efflux pump MacAB-TolC has been identified in diverse gram-negative bacteria including Escherichia coli. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein MacA to form a functional tripartite complex. In this study, we used a chimeric protein containing the tip region of the TolC α-barrel to investigate the role of the TolC α-barrel tip region with regard to its interaction with MacA. The chimeric protein formed a stable complex with MacA, and the complex formation was abolished by substitution at the functionally essential residues located at the MacA α-helical tip region. Electron microscopic study delineated that this complex was made by tip-to-tip interaction between the tip regions of the α-barrels of TolC and MacA, which correlated well with the TolC and MacA complex calculated by molecular dynamics. Taken together, our results demonstrate that the MacA hexamer interacts with TolC in a tip-to-tip manner, and implies the manner by which MacA induces opening of the TolC channel.

Functional Implications of an Intermeshing Cogwheel-like Interaction between TolC and MacA in the Action of Macrolide-specific Efflux Pump MacAB-TolC*

PubMed Central

Xu, Yongbin; Song, Saemee; Moeller, Arne; Kim, Nahee; Piao, Shunfu; Sim, Se-Hoon; Kang, Mooseok; Yu, Wookyung; Cho, Hyun-Soo; Chang, Iksoo; Lee, Kangseok; Ha, Nam-Chul

2011-01-01

Macrolide-specific efflux pump MacAB-TolC has been identified in diverse Gram-negative bacteria including Escherichia coli. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein MacA to form a functional tripartite complex. In this study, we used a chimeric protein containing the tip region of the TolC α-barrel to investigate the role of the TolC α-barrel tip region with regard to its interaction with MacA. The chimeric protein formed a stable complex with MacA, and the complex formation was abolished by substitution at the functionally essential residues located at the MacA α-helical tip region. Electron microscopic study delineated that this complex was made by tip-to-tip interaction between the tip regions of the α-barrels of TolC and MacA, which correlated well with the TolC and MacA complex calculated by molecular dynamics. Taken together, our results demonstrate that the MacA hexamer interacts with TolC in a tip-to-tip manner, and implies the manner by which MacA induces opening of the TolC channel. PMID:21325274

48 CFR 30.607 - Subcontract administration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Administration 30.607 Subcontract... subcontract level, the CFAO for the subcontractor shall furnish a copy of the negotiation memorandum or the... the prime contractor level. ...

Fiverr MacGyver

NASA Astrophysics Data System (ADS)

Hut, Rolf; van de Giesen, Nick; Larson, Martha

2014-05-01

Crowdsourcing has become popular over the past years, also for scientific endeavors. There are many Citizen Science projects and crowdfunding platforms, such as Kickstarter, that are make helpful contributions to moving environmental science forward. An interesting underused source of useful crowd-derived contributions to research is the website Fiverr.com. On this platform, thousands of people, acting as small-scale freelance contractors, offer their skills in the form of services. The platform offers a chance for people to take a hobby, skill, or pastime and make it something more by reaching out to a wider audience and by receiving a payment in return for services. As is typical of other crowdsourcing platforms, the tasks are small and usually self contained. As the name Fiverr suggests, offers start at US5 to provide a particular service. Services offered range from graphic design, to messages sung or spoken with various styles or accents, to complete apps for Android or iPhone. Skill providers on the platform can accept a range of variation of definition in the tasks, some can be described in general terms, for others it is more appropriate to provide examples. Fiverr provides a central location for those offering skills and those needing services to find each other, it makes it possible to communicate and exchange files, to make payments, and it provides support for resolving disputes. In all cases, it is important to keep expectations aligned with the nature of the platform: quality can and will vary. Ultimately, the critical contribution of Fiverr is not to replace professional services or otherwise save money, but rather to provide access to a large group of people with specialized skills who are able to make a contribution on short notice. In the context of this session, it can be considered a pool of people with MacGyver skills lying in wait of a MacGyyer task to attack. There are many ways in which Fiverr tasks, which are called 'gigs', can be useful in

MacDill Air Force Base > Home

Science.gov Websites

Force Base, Fla., May 22, 2018. Police Week is a national observance that pays tribute to the law rescue 5 in Tampa Bay Law Day 2018 MacDill Captain discovers endless possibilities MacDill hosts Sexual ., May 22, 2018. Police Week is a national observance that pays tribute to the law enforcement officers

Contingency Contractor Optimization Phase 3 Sustainment Software Design Document - Contingency Contractor Optimization Tool - Prototype

DOE Office of Scientific and Technical Information (OSTI.GOV)

Durfee, Justin David; Frazier, Christopher Rawls; Bandlow, Alisa

This document describes the final software design of the Contingency Contractor Optimization Tool - Prototype. Its purpose is to provide the overall architecture of the software and the logic behind this architecture. Documentation for the individual classes is provided in the application Javadoc. The Contingency Contractor Optimization project is intended to address Department of Defense mandates by delivering a centralized strategic planning tool that allows senior decision makers to quickly and accurately assess the impacts, risks, and mitigation strategies associated with utilizing contract support. The Contingency Contractor Optimization Tool - Prototype was developed in Phase 3 of the OSD ATLmore » Contingency Contractor Optimization project to support strategic planning for contingency contractors. The planning tool uses a model to optimize the Total Force mix by minimizing the combined total costs for selected mission scenarios. The model optimizes the match of personnel types (military, DoD civilian, and contractors) and capabilities to meet mission requirements as effectively as possible, based on risk, cost, and other requirements.« less

23 CFR Appendix C to Subpart A of... - Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391)

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) C Appendix C to Subpart A of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF... Part 230—Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) EC14OC91.000 ...

7 CFR 1788.12 - Contractors' bonds.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE (CONTINUED) RUS FIDELITY AND INSURANCE REQUIREMENTS FOR ELECTRIC AND TELECOMMUNICATIONS BORROWERS Insurance for Contractors, Engineers, and Architects, Electric Borrowers § 1788.12 Contractors' bonds. Electric borrowers shall require contractors to obtain contractors' bonds when required by part 1726...

7 CFR 1788.12 - Contractors' bonds.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE (CONTINUED) RUS FIDELITY AND INSURANCE REQUIREMENTS FOR ELECTRIC AND TELECOMMUNICATIONS BORROWERS Insurance for Contractors, Engineers, and Architects, Electric Borrowers § 1788.12 Contractors' bonds. Electric borrowers shall require contractors to obtain contractors' bonds when required by part 1726...

7 CFR 1788.12 - Contractors' bonds.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE (CONTINUED) RUS FIDELITY AND INSURANCE REQUIREMENTS FOR ELECTRIC AND TELECOMMUNICATIONS BORROWERS Insurance for Contractors, Engineers, and Architects, Electric Borrowers § 1788.12 Contractors' bonds. Electric borrowers shall require contractors to obtain contractors' bonds when required by part 1726...

7 CFR 1788.12 - Contractors' bonds.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE (CONTINUED) RUS FIDELITY AND INSURANCE REQUIREMENTS FOR ELECTRIC AND TELECOMMUNICATIONS BORROWERS Insurance for Contractors, Engineers, and Architects, Electric Borrowers § 1788.12 Contractors' bonds. Electric borrowers shall require contractors to obtain contractors' bonds when required by part 1726...

76 FR 39015 - Contractor Performance Information

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

...] Contractor Performance Information AGENCY: Environmental Protection Agency (EPA), ACTION: Direct final rule... contractor performance information. EPA is issuing a final rule because the changes are procedural in nature... Institutes of Health's Contractor Performance System (CPS) to the Department of Defense's Contractor...

48 CFR 46.105 - Contractor responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is..., and furnishing such information to the Government as required. (b) The contractor may be required to...

Environmental Impact Statement for Proposed Closure of Los Angeles Air Force Base, California and Relocation of Space Systems Division

DTIC Science & Technology

1990-05-01

FFRDC); and the Systems Engineering Technical Assistance (SETA) contractor to selected Air Force bases including: Vandenberg AFB California; March AFB...05/21/90 comptroller, acquisition civil engineering , legal, security, communications-computer systems, product assurance, and safety, among others...housing units were constructed in 1983. The Fort MacArthur Housing Area also includes administrative offices, several warehouses, and civil engineering

Modeling C-Band Co-Channel Interference From AeroMACS Omni-Directional Antennas to Mobile Satellite Service Feeder Uplinks

NASA Technical Reports Server (NTRS)

Wilson, Jeffrey D.

2011-01-01

A new C-band (5091 to 5150 MHz) airport communications system designated as Aeronautical Mobile Airport Communications System (AeroMACS) is being planned under the Federal Aviation Administration s NextGen program. An interference analysis software program, Visualyse Professional (Transfinite Systems Ltd), is being utilized to provide guidelines on limitations for AeroMACS transmitters to avoid interference with other systems. A scenario consisting of a single omni-directional transmitting antenna at each of the major contiguous United States airports is modeled and the steps required to build the model are reported. The results are shown to agree very well with a previous study.

CoR-MAC: Contention over Reservation MAC Protocol for Time-Critical Services in Wireless Body Area Sensor Networks

PubMed Central

Yu, Jeongseok; Park, Laihyuk; Park, Junho; Cho, Sungrae; Keum, Changsup

2016-01-01

Reserving time slots for urgent data, such as life-critical information, seems to be very attractive to guarantee their deadline requirements in wireless body area sensor networks (WBASNs). On the other hand, this reservation imposes a negative impact on performance for the utilization of a channel. This paper proposes a new channel access scheme referred to as the contention over reservation MAC (CoR-MAC) protocol for time-critical services in wireless body area sensor networks. CoR-MAC uses the dual reservation; if the reserved time slots are known to be vacant, other nodes can access the time slots by contention-based reservation to maximize the utilization of a channel and decrease the delay of the data. To measure the effectiveness of the proposed scheme against IEEE 802.15.4 and IEEE 802.15.6, we evaluated their performances with various performance indexes. The CoR-MAC showed 50% to 850% performance improvement in terms of the delay of urgent and time-critical data according to the number of nodes. PMID:27171085

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Contractors. 68.87 Section 68.87... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This section applies to contractors performing maintenance or repair, turnaround, major renovation, or...

49 CFR 10.27 - Government contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Government contractors. 10.27 Section 10.27... INDIVIDUALS Maintenance of Records § 10.27 Government contractors. When the Department provides by a contract..., Criminal Penalties, any such contractor and any employee of the contractor are considered, in accordance...

49 CFR 199.245 - Contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Contractor employees. 199.245 Section 199.245... Prevention Program § 199.245 Contractor employees. (a) With respect to those covered employees who are contractors or employed by a contractor, an operator may provide by contract that the alcohol testing...

38 CFR 46.8 - Independent contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Independent contractors... contractors. Independent contractors acting on behalf of the Department of Veterans Affairs are subject to the... provide the contractor with notice that a report of a clinical privileges action will be filed with the...

49 CFR 199.115 - Contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Contractor employees. 199.115 Section 199.115... § 199.115 Contractor employees. With respect to those employees who are contractors or employed by a contractor, an operator may provide by contract that the drug testing, education, and training required by...

7 CFR 1726.27 - Contractor's bonds.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Contractor's bonds. 1726.27 Section 1726.27... AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES General § 1726.27 Contractor's bonds. (a) RUS Form 168b, Contractor's Bond, shall be used when a contractor's bond is required by RUS Forms 200, 257...

48 CFR 47.207-5 - Contractor responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor....207-5 Contractor responsibilities. Contractor responsibilities vary with the kinds of freight to be... furnished by the contractor. Otherwise, state that the contractor shall furnish clean and sound closed-type...

Isoflurane administration before ischemia and during reperfusion attenuates ischemia/reperfusion-induced injury of isolated rabbit lungs.

PubMed

Liu, R; Ishibe, Y; Ueda, M; Hang, Y

1999-09-01

To investigate the effects of isoflurane on ischemia/ reperfusion (IR)-induced lung injury, we administered isoflurane before ischemia or during reperfusion. Isolated rabbit lungs were divided into the following groups: control (n = 6), perfused and ventilated for 120 min without ischemia; ISO-control (n = 6), 1 minimum alveolar anesthetic concentration (MAC) isoflurane was administered for 30 min before 120 min continuous perfusion; IR (n = 6), ischemia for 60 min, followed by 60 min reperfusion; IR-ISO1 and IR-ISO2, ischemia followed by reperfusion and 1 MAC (n = 6) or 2 MAC (n = 6) isoflurane for 60 min; ISO-IR (n = 6), 1 MAC isoflurane was administered for 30 min before ischemia, followed by IR. During these maneuvers, we measured total pulmonary vascular resistance (Rt), coefficient of filtration (Kfc), and lung wet to dry ratio (W/D). The results indicated that administration of isoflurane during reperfusion inhibited an IR-induced increase in Kfc and W/D ratio. Furthermore, isoflurane at 2 MAC, but not 1 MAC, significantly inhibited an IR-induced increase in Rt. The administration of isoflurane before ischemia significantly attenuated the increase in IR-induced Kfc, W/D, and Rt. Our results suggest that the administration of isoflurane before ischemia and during reperfusion protects against ischemia-reperfusion-induced injury in isolated rabbit lungs.

48 CFR 18.102 - Central contractor registration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Central contractor... Central contractor registration. Contractors are not required to be registered in the Central Contractor.... (See 4.1102). However, contractors are required to register with CCR in order to gain access to the...

Accuracy of the MacArthur competence assessment tool for clinical research (MacCAT-CR) for measuring children's competence to consent to clinical research.

PubMed

Hein, Irma M; Troost, Pieter W; Lindeboom, Robert; Benninga, Marc A; Zwaan, C Michel; van Goudoever, Johannes B; Lindauer, Ramón J L

2014-12-01

An objective assessment of children's competence to consent to research participation is currently not possible. Age limits for asking children's consent vary considerably between countries, and, to our knowledge, the correlation between competence and children's age has never been systematically investigated. To test a standardized competence assessment instrument for children by modifying the MacArthur Competence Assessment Tool for Clinical Research (MacCAT-CR), to investigate its reliability and validity, and to examine the correlation of its assessment with age and estimate cutoff ages. This prospective study included children and adolescents aged 6 to 18 years in the inpatient and outpatient departments of allergology, gastroenterology, oncology, ophthalmology, and pulmonology from January 1, 2012, through January 1, 2014. Participants were eligible for clinical research studies, including observational studies and randomized clinical trials. Competence judgments by experts aware of the 4 relevant criteria-understanding, appreciation, reasoning, and choice-were used to establish the reference standard. The index test was the MacCAT-CR, which used a semistructured interview format. Interrater reliability, validity, and dimensionality of the MacCAT-CR and estimated cutoff ages for competence. Of 209 eligible patients, we included 161 (mean age, 10.6 years; 47.2% male). Good reproducibility of MacCAT-CR total and subscale scores was observed (intraclass correlation coefficient range, 0.68-0.92). We confirmed unidimensionality of the MacCAT-CR. By the reference standard, we judged 54 children (33.5%) to be incompetent; by the MacCAT-CR, 61 children (37.9%). Criterion-related validity of MacCAT-CR scores was supported by high overall accuracy in correctly classifying children as competent against the reference standard (area under the receiver operating characteristics curve, 0.78). Age was a good predictor of competence on the MacCAT-CR (area under the receiver

48 CFR 2427.305-2 - Administration by the Government.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Government. 2427.305-2 Section 2427.305-2 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305-2 Administration by the Government. (b) Contractor reports. Contractors shall complete...

Paired lunar meteorites MAC88104 and MAC88105 - A new 'FAN' of lunar petrology

NASA Astrophysics Data System (ADS)

Neal, Clive R.; Taylor, Lawrence A.; Lui, Yun-Gang; Schmitt, Roman A.

1991-11-01

To determine the chemical characteristics of the MAC88104/5 meteorite six thin sections and three bulk samples were analyzed by electron microprobe and instrumental neutron activation. It is concluded that this meteorite is dominated by lithologies of the ferroan anorthosite suite and contains abundant granulitized highland clasts, devitrified glass beads of impact origin, and two small clasts of basaltic origin. It is suggested that one of these basaltic clasts, clast E, is mesostasis material, and clast G is similar to the very low-Ti or low-Ti/high-alumina mare basalts. Impact melt clasts MAC88105, 69, and 72 have major and trace element compositions similar to the bulk meteorite.

4 CFR 83.19 - Government contractors.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Government contractors. 83.19 Section 83.19 Accounts... contractors. When GAO provides by a contract for the operation by or on behalf of GAO of a system of personnel... of this part to be applied to such system. Any such contractor and any employee of such contractor...

32 CFR 1701.16 - Contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Contractors. 1701.16 Section 1701.16 National... Under the Privacy Act of 1974 § 1701.16 Contractors. (a) Any approved contract for the operation of a... prescribed by the Federal Acquisition Regulations (FAR) at 48 CFR part 24, requiring the contractor to comply...

Photocopy of drawing (original drawing of MacDill Field in possession ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photocopy of drawing (original drawing of MacDill Field in possession of MacDill Air Force Base, Civil Engineering, Tampa, Florida; 1952 architectural drawings by Strategic Air Command, MacDill Air Force Base) BASE LAYOUT, 1952 - MacDill Air Force Base, Bounded by City of Tampa North, Tampa Bay South, Old Tampa Bay West, & Hillsborough Bay East, Tampa, Hillsborough County, FL

Middle Atmosphere Cooperation/Summer in Northern Europe (MAC/SINE) and MAC/Epsilon

NASA Technical Reports Server (NTRS)

Thrane, E. V.

1989-01-01

Two major international campaigns dedicated to the study of middle atmosphere dynamics in high latitudes were successfully completed in 1987. MAC/SINE (Middle Atmosphere Cooperation/Summer in Northern Europe) was carried out during the period 7 June to 19 July, whereas MAC/Epsilon took place in the period 12 October to 15 November. In both campaigns a large number of ground based and rocket techniques were used in a concerted effort to map the dynamical structure of the middle atmosphere over Northern Europe. Although the analysis of the observations has only just started, it is clear that a large and unique data set was obtained, which is believed will provide new insight into the dynamical processes in this interesting region of the atmosphere. A brief overview of the campaigns, their scientific aims, organization and structure is presented.

Library Signage: Applications for the Apple Macintosh and MacPaint.

ERIC Educational Resources Information Center

Diskin, Jill A.; FitzGerald, Patricia

1984-01-01

Describes specific applications of the Macintosh computer at Carnegie-Mellon University Libraries, where MacPaint was used as a flexible, easy to use, and powerful tool to produce informational, instructional, and promotional signage. Profiles of system hardware and software, an evaluation of the computer program MacPaint, and MacPaint signage…

48 CFR 1845.502 - Contractor responsibility.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor responsibility. 1845.502 Section 1845.502 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Contractors 1845.502 Contractor responsibility. ...

48 CFR 4.705-2 - Pay administration records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Pay administration records. 4.705-2 Section 4.705-2 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL ADMINISTRATIVE MATTERS Contractor Records Retention 4.705-2 Pay administration records. (a...

48 CFR 3009.171-8 - Ineligible contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Ineligible contractors..., HOMELAND SECURITY ACQUISITION REGULATION (HSAR) ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Responsible Prospective Contractors 3009.171-8 Ineligible contractors. Any business concern determined to be ineligible...

Cooperative Energy Harvesting-Adaptive MAC Protocol for WBANs

PubMed Central

Esteves, Volker; Antonopoulos, Angelos; Kartsakli, Elli; Puig-Vidal, Manel; Miribel-Català, Pere; Verikoukis, Christos

2015-01-01

In this paper, we introduce a cooperative medium access control (MAC) protocol, named cooperative energy harvesting (CEH)-MAC, that adapts its operation to the energy harvesting (EH) conditions in wireless body area networks (WBANs). In particular, the proposed protocol exploits the EH information in order to set an idle time that allows the relay nodes to charge their batteries and complete the cooperation phase successfully. Extensive simulations have shown that CEH-MAC significantly improves the network performance in terms of throughput, delay and energy efficiency compared to the cooperative operation of the baseline IEEE 802.15.6 standard. PMID:26029950

BFT replication resistant to MAC attacks

NASA Astrophysics Data System (ADS)

Zbierski, Maciej

2016-09-01

Over the last decade numerous Byzantine fault-tolerant (BFT) replication protocols have been proposed in the literature. However, the vast majority of these solutions reuse the same authentication scheme, which makes them susceptible to a so called MAC attack. Such vulnerability enables malicious clients to undetectably prevent the replicated service from processing incoming client requests, and consequently making it permanently unavailable. While some BFT protocols attempted to address this issue by using different authentication mechanisms, they at the same time significantly degraded the performance achieved in correct environments. This article presents a novel adaptive authentication mechanism which can be combined with practically any Byzantine fault-tolerant replication protocol. Unlike previous solutions, the proposed scheme dynamically switches between two operation modes to combine high performance in correct environments and liveness during MAC attacks. The experiment results presented in the article demonstrate that the proposed mechanism can sufficiently tolerate MAC attacks without introducing any observable overhead whenever no faults are present.

48 CFR 1602.170-4 - Contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor. 1602.170-4 Section 1602.170-4 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES... 1602.170-4 Contractor. Contractor means carrier. ...

48 CFR 1609.471 - Contractor certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor certification... EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Debarment, Suspension, and Ineligibility 1609.471 Contractor certification. All FEHBP carriers and applicant carriers...

Operational effectiveness of a Multiple Aquila Control System (MACS)

NASA Technical Reports Server (NTRS)

Brown, R. W.; Flynn, J. D.; Frey, M. R.

1983-01-01

The operational effectiveness of a multiple aquila control system (MACS) was examined under a variety of remotely piloted vehicle (RPV) mission configurations. The set of assumptions and inputs used to form the rules under which a computerized simulation of MACS was run is given. The characteristics that are to govern MACS operations include: the battlefield environment that generates the requests for RPV missions, operating time-lines of the RPV-peculiar equipment, maintenance requirements, and vulnerability to enemy fire. The number of RPV missions and the number of operation days are discussed. Command, control, and communication data rates are estimated by determining how many messages are passed and what information is necessary in them to support ground coordination between MACS sections.

48 CFR 752.7013 - Contractor-mission relationships.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor-mission....7013 Contractor-mission relationships. For use in all USAID contracts involving performance overseas.... Contractor-Mission Relationships (OCT 1989) (a) The Contractor acknowledges that this contract is an...

Modeling Woven Polymer Matrix Composites with MAC/GMC

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Arnold, Steven M. (Technical Monitor)

2000-01-01

NASA's Micromechanics Analysis Code with Generalized Method of Cells (MAC/GMC) is used to predict the elastic properties of plain weave polymer matrix composites (PMCs). The traditional one step three-dimensional homogertization procedure that has been used in conjunction with MAC/GMC for modeling woven composites in the past is inaccurate due to the lack of shear coupling inherent to the model. However, by performing a two step homogenization procedure in which the woven composite repeating unit cell is homogenized independently in the through-thickness direction prior to homogenization in the plane of the weave, MAC/GMC can now accurately model woven PMCs. This two step procedure is outlined and implemented, and predictions are compared with results from the traditional one step approach and other models and experiments from the literature. Full coupling of this two step technique with MAC/ GMC will result in a widely applicable, efficient, and accurate tool for the design and analysis of woven composite materials and structures.

MAC layer security issues in wireless mesh networks

NASA Astrophysics Data System (ADS)

Reddy, K. Ganesh; Thilagam, P. Santhi

2016-03-01

Wireless Mesh Networks (WMNs) have emerged as a promising technology for a broad range of applications due to their self-organizing, self-configuring and self-healing capability, in addition to their low cost and easy maintenance. Securing WMNs is more challenging and complex issue due to their inherent characteristics such as shared wireless medium, multi-hop and inter-network communication, highly dynamic network topology and decentralized architecture. These vulnerable features expose the WMNs to several types of attacks in MAC layer. The existing MAC layer standards and implementations are inadequate to secure these features and fail to provide comprehensive security solutions to protect both backbone and client mesh. Hence, there is a need for developing efficient, scalable and integrated security solutions for WMNs. In this paper, we classify the MAC layer attacks and analyze the existing countermeasures. Based on attacks classification and countermeasures analysis, we derive the research directions to enhance the MAC layer security for WMNs.

48 CFR 852.237-70 - Contractor responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor....237-70 Contractor responsibilities. As prescribed in 837.110, insert the following clause: Contractor Responsibilities (APR 1984) The contractor shall obtain all necessary licenses and/or permits required to perform...

48 CFR 1509.170-8 - Contractor Performance Report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor Performance... AGENCY ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Contractor Performance Evaluations 1509.170-8 Contractor Performance Report. (a) Contractor Performance Reports (interim and final) must be prepared...

48 CFR 52.241-5 - Contractor's Facilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor's Facilities....241-5 Contractor's Facilities. As prescribed in 41.501(c)(4), insert a clause substantially the same as the following: Contractor's Facilities (FEB 1995) (a) The Contractor, at its expense, unless...

14 CFR 1245.108 - License to contractor.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false License to contractor. 1245.108 Section... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.108 License to contractor. (a) Each contractor.... The license extends to the contractor's domestic subsidiaries and affiliates, if any, within the...

48 CFR 52.247-28 - Contractor's Invoices.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor's Invoices. 52....247-28 Contractor's Invoices. As prescribed in 47.207-9(c), insert the following clause in... services: Contractor's Invoices (APR 1984) The Contractor shall submit itemized invoices as instructed by...

48 CFR 33.207 - Contractor certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor certification... CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 33.207 Contractor certification. (a) Contractors shall provide the certification specified in paragraph (c) of this section when...

48 CFR 725.703 - Contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor employees. 725... SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Source, Origin, and Nationality 725.703 Contractor employees. (a... on employees or consultants of either contractors or subcontractors providing services under an USAID...

42 CFR 423.2110 - MAC reviews on its own motion.

Code of Federal Regulations, 2011 CFR

2011-10-01

... its own motion, it will mail the results of its action to the enrollee and to CMS or the IRE, as... 42 Public Health 3 2011-10-01 2011-10-01 false MAC reviews on its own motion. 423.2110 Section 423..., and Judicial Review § 423.2110 MAC reviews on its own motion. (a) General rule. The MAC may decide on...

48 CFR 1845.502-70 - Contractor-acquired property.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor-acquired... Possession of Contractors 1845.502-70 Contractor-acquired property. All contractor-acquired property must be... contractor-acquired. (2) Submission of DD Form 1419, DOD Industrial Plant Requisition, or equivalent format...

48 CFR 1252.242-71 - Contractor testimony.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor testimony. 1252... Contractor testimony. As prescribed in (TAR) 48 CFR 1242.7000(b), insert the following clause: Contractor Testimony (OCT 1994) All requests for the testimony of the Contractor or its employees, and any intention to...

24 CFR 242.53 - Excluded contractors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Excluded contractors. 242.53... MORTGAGE INSURANCE FOR HOSPITALS Construction § 242.53 Excluded contractors. (a) Contracts relating to the... participation in federal programs, including but not limited to: A general contractor, a subcontractor, or...

40 CFR 35.6600 - Contractor claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Contractor claims. 35.6600 Section 35... Actions Procurement Requirements Under A Cooperative Agreement § 35.6600 Contractor claims. (a) General... prepared by the contractor to support a claim against the recipient; and (4) The award official determines...

Mammalian Synthetic Biology: Time for Big MACs.

PubMed

Martella, Andrea; Pollard, Steven M; Dai, Junbiao; Cai, Yizhi

2016-10-21

The enabling technologies of synthetic biology are opening up new opportunities for engineering and enhancement of mammalian cells. This will stimulate diverse applications in many life science sectors such as regenerative medicine, development of biosensing cell lines, therapeutic protein production, and generation of new synthetic genetic regulatory circuits. Harnessing the full potential of these new engineering-based approaches requires the design and assembly of large DNA constructs-potentially up to chromosome scale-and the effective delivery of these large DNA payloads to the host cell. Random integration of large transgenes, encoding therapeutic proteins or genetic circuits into host chromosomes, has several drawbacks such as risks of insertional mutagenesis, lack of control over transgene copy-number and position-specific effects; these can compromise the intended functioning of genetic circuits. The development of a system orthogonal to the endogenous genome is therefore beneficial. Mammalian artificial chromosomes (MACs) are functional, add-on chromosomal elements, which behave as normal chromosomes-being replicating and portioned to daughter cells at each cell division. They are deployed as useful gene expression vectors as they remain independent from the host genome. MACs are maintained as a single-copy and can accommodate multiple gene expression cassettes of, in theory, unlimited DNA size (MACs up to 10 megabases have been constructed). MACs therefore enabled control over ectopic gene expression and represent an excellent platform to rapidly prototype and characterize novel synthetic gene circuits without recourse to engineering the host genome. This review describes the obstacles synthetic biologists face when working with mammalian systems and how the development of improved MACs can overcome these-particularly given the spectacular advances in DNA synthesis and assembly that are fuelling this research area.

Vehicle Health Management Communications Requirements for AeroMACS

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Clements, Donna J.; Apaza, Rafael D.

2012-01-01

As the development of standards for the aeronautical mobile airport communications system (AeroMACS) progresses, the process of identifying and quantifying appropriate uses for the system is progressing. In addition to defining important elements of AeroMACS standards, indentifying the systems uses impacts AeroMACS bandwidth requirements. Although an initial 59 MHz spectrum allocation for AeroMACS was established in 2007, the allocation may be inadequate; studies have indicated that 100 MHz or more of spectrum may be required to support airport surface communications. Hence additional spectrum allocations have been proposed. Vehicle health management (VHM) systems, which can produce large volumes of vehicle health data, were not considered in the original bandwidth requirements analyses, and are therefore of interest in supporting proposals for additional AeroMACS spectrum. VHM systems are an emerging development in air vehicle safety, and preliminary estimates of the amount of data that will be produced and transmitted off an aircraft, both in flight and on the ground, have been prepared based on estimates of data produced by on-board vehicle health sensors and initial concepts of data processing approaches. This allowed an initial estimate of VHM data transmission requirements for the airport surface. More recently, vehicle-level systems designed to process and analyze VHM data and draw conclusions on the current state of vehicle health have been undergoing testing and evaluation. These systems make use of vehicle system data that is mostly different from VHM data considered previously for airport surface transmission, and produce processed system outputs that will be also need to be archived, thus generating additional data load for AeroMACS. This paper provides an analysis of airport surface data transmission requirements resulting from the vehicle level reasoning systems, within the context of overall VHM data requirements.

32 CFR 310.12 - Government contractors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Government contractors. 310.12 Section 310.12... PROGRAM DOD PRIVACY PROGRAM Systems of Records § 310.12 Government contractors. (a) Applicability to government contractors. (1) When a DoD Component contract requires the operation or maintenance of a system...

32 CFR 310.12 - Government contractors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Government contractors. 310.12 Section 310.12... PROGRAM DOD PRIVACY PROGRAM Systems of Records § 310.12 Government contractors. (a) Applicability to government contractors. (1) When a DoD Component contract requires the operation or maintenance of a system...

32 CFR 310.12 - Government contractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Government contractors. 310.12 Section 310.12... PROGRAM DOD PRIVACY PROGRAM Systems of Records § 310.12 Government contractors. (a) Applicability to government contractors. (1) When a DoD Component contract requires the operation or maintenance of a system...

32 CFR 310.12 - Government contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Government contractors. 310.12 Section 310.12... PROGRAM DOD PRIVACY PROGRAM Systems of Records § 310.12 Government contractors. (a) Applicability to government contractors. (1) When a DoD Component contract requires the operation or maintenance of a system...

32 CFR 310.12 - Government contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Government contractors. 310.12 Section 310.12... PROGRAM DOD PRIVACY PROGRAM Systems of Records § 310.12 Government contractors. (a) Applicability to government contractors. (1) When a DoD Component contract requires the operation or maintenance of a system...

Research on low-latency MAC protocols for wireless sensor networks

NASA Astrophysics Data System (ADS)

He, Chenguang; Sha, Xuejun; Lee, Chankil

2007-11-01

Energy-efficient should not be the only design goal in MAC protocols for wireless sensor networks, which involve the use of battery-operated computing and sensing devices. Low-latency operation becomes the same important as energy-efficient in the case that the traffic load is very heavy or the real-time constrain is used in applications like tracking or locating. This paper introduces some causes of traditional time delays which are inherent in a multi-hops network using existing WSN MAC protocols, illuminates the importance of low-latency MAC design for wireless sensor networks, and presents three MACs as examples of low-latency protocols designed specially for sleep delay, wait delay and wakeup delay in wireless sensor networks, respectively. The paper also discusses design trade-offs with emphasis on low-latency and points out their advantages and disadvantages, together with some design considerations and suggestions for MAC protocols for future applications and researches.

29 CFR 500.41 - Farm labor contractor is responsible for actions of his farm labor contractor employee.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., prior to such employee's engagement in any activity enumerated in section 3(6) of the Act. A farm labor... farm labor contractor employee. 500.41 Section 500.41 Labor Regulations Relating to Labor (Continued... PROTECTION Registration of Farm Labor Contractors and Employees of Farm Labor Contractors Engaged in Farm...

29 CFR 500.41 - Farm labor contractor is responsible for actions of his farm labor contractor employee.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., prior to such employee's engagement in any activity enumerated in section 3(6) of the Act. A farm labor... farm labor contractor employee. 500.41 Section 500.41 Labor Regulations Relating to Labor (Continued... PROTECTION Registration of Farm Labor Contractors and Employees of Farm Labor Contractors Engaged in Farm...

Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter

PubMed Central

Lu, Shuo; Zgurskaya, Helen I.

2012-01-01

Summary MacB is a founding member of the Macrolide Exporter family of transporters belonging to the ATP-Binding Cassette superfamily. These proteins are broadly represented in genomes of both gram-positive and gram-negative bacteria and are implicated in virulence and protection against antibiotics and peptide toxins. MacB transporter functions together with MacA, a periplasmic membrane fusion protein, which stimulates MacB ATPase. In gram-negative bacteria, MacA is believed to couple ATP hydrolysis to transport of substrates across the outer membrane through a TolC-like channel. In this study, we report a real-time analysis of concurrent ATP hydrolysis and assembly of MacAB-TolC complex. MacB binds nucleotides with a low millimolar affinity and fast on- and off-rates. In contrast, MacA-MacB complex is formed with a nanomolar affinity, which further increases in the presence of ATP. Our results strongly suggest that association between MacA and MacB is stimulated by ATP binding to MacB but remains unchanged during ATP hydrolysis cycle. We also found that the large periplasmic loop of MacB plays the major role in coupling reactions separated in two different membranes. This loop is required for MacA-dependent stimulation of MacB ATPase and at the same time, contributes to recruitment of TolC into a trans-envelope complex. PMID:23057817

48 CFR 970.4402 - Contractor purchasing system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor purchasing... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Management and Operating Contractor Purchasing 970.4402 Contractor purchasing system. ...

Photocopy of drawing (original drawing of MacDill Field in possession ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photocopy of drawing (original drawing of MacDill Field in possession of MacDill Air Force Base, Civil Engineering, Tampa, Florida; site plan dated December, 1942) BASE LAYOUT, DECEMBER 1942 - MacDill Air Force Base, Bounded by City of Tampa North, Tampa Bay South, Old Tampa Bay West, & Hillsborough Bay East, Tampa, Hillsborough County, FL

34 CFR 5b.12 - Contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Contractors. 5b.12 Section 5b.12 Education Office of the Secretary, Department of Education PRIVACY ACT REGULATIONS § 5b.12 Contractors. (a) All contracts entered into on or after September 27, 1975 which require a contractor to maintain or on behalf of the...

The MAC aerosol climatology

NASA Astrophysics Data System (ADS)

Kinne, S.

2015-12-01

Aerosol is highly diverse in space and time. And many different aerosol optical properties are needed (consistent to each other) for the determination of radiative effects. To sidestep a complex (and uncertain) aerosol treatment (emission to mass to optics) a monthly gridded climatology for aerosol properties has been developed. This MPI Aerosol Climatology (MAC) is strongly tied to observational statistics for aerosol column optical properties by AERONET (over land) and by MAN (over oceans). To fill spatial gaps, to address decadal change and to address vertical variability, these sparsely distributed local data are extended with central data of an ensemble of output from global models with complex aerosol modules. This data merging in performed for aerosol column amount (AOD), for aerosol size (AOD,fine) and for aerosol absorption (AAOD). The resulting MAC aerosol climatology is an example for the combination of high quality local observations with spatial, temporal and vertical context from model simulations.

Building America Expert Meeting Report: Transitioning Traditional HVAC Contractors to Whole House Performance Contractors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burdick, A.

This report outlines findings resulting from a U.S. Department of Energy Building America expert meeting to determine how HVAC companies can transition from a traditional contractor status to a service provider for whole house energy upgrade contracting. IBACOS has embarked upon a research effort under the Building America Program to understand business impacts and change management strategies for HVAC companies. HVAC companies can implement these strategies in order to quickly transition from a 'traditional' heating and cooling contractor to a service provider for whole house energy upgrade contracting. Due to HVAC service contracts, which allow repeat interaction with homeowners, HVACmore » companies are ideally positioned in the marketplace to resolve homeowner comfort issues through whole house energy upgrades. There are essentially two primary ways to define the routes of transition for an HVAC contractor taking on whole house performance contracting: (1) Sub-contracting out the shell repair/upgrade work; and (2) Integrating the shell repair/upgrade work into their existing business. IBACOS held an Expert Meeting on the topic of Transitioning Traditional HVAC Contractors to Whole House Performance Contractors on March 29, 2011 in San Francisco, CA. The major objectives of the meeting were to: Review and validate the general business models for traditional HVAC companies and whole house energy upgrade companies Review preliminary findings on the differences between the structure of traditional HVAC Companies and whole house energy upgrade companies Seek industry input on how to structure information so it is relevant and useful for traditional HVAC contractors who are transitioning to becoming whole house energy upgrade contractors Seven industry experts identified by IBACOS participated in the session along with one representative from the National Renewable Energy Laboratory (NREL). The objective of the meeting was to validate the general operational

48 CFR 51.104 - Furnishing assistance to contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractors. 51.104 Section 51.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT USE OF GOVERNMENT SOURCES BY CONTRACTORS Contractor Use of Government Supply Sources 51.104 Furnishing assistance to contractors. After receiving an activity address code, the contracting...

48 CFR 52.246-1 - Contractor Inspection Requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor Inspection....246-1 Contractor Inspection Requirements. As prescribed in 46.301, insert the following clause: Contractor Inspection Requirements (APR 1984) The Contractor is responsible for performing or having...

48 CFR 52.204-7 - Central Contractor Registration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Central Contractor....204-7 Central Contractor Registration. As prescribed in 4.1105, use the following clause: Central Contractor Registration (APR 2008) (a) Definitions. As used in this clause— Central Contractor Registration...

48 CFR 970.5244-1 - Contractor purchasing system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor purchasing... for Management and Operating Contracts 970.5244-1 Contractor purchasing system. As prescribed in 970.4403 insert the following clause: Contractor Purchasing System (AUG 2009) (a) General. The Contractor...

48 CFR 45.503 - Support property administrator findings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Support property administrator findings. 45.503 Section 45.503 Federal Acquisition Regulations System FEDERAL ACQUISITION... property administrator findings. In instances where the prime contractor does not concur with the findings...

Generic Drug Cost Containment in Medicaid: Lessons from Five State MAC Programs

PubMed Central

Abramson, Richard G.; Harrington, Catherine A.; Missmar, Raad; Li, Susan P.; Mendelson, Daniel N.

2004-01-01

In Medicaid, generic drug cost containment revolves around two programs: the Federal upper limit (FUL) program and State maximum allowable cost (MAC) programs. This article analyzes MAC programs in five States and finds considerable variation between these programs and the FUL program in both size and pricing aggressiveness. We conclude that expansion of existing MAC programs and creation of new ones could contribute to cost containment efforts nationwide. Options for States seeking to optimize their efforts include focusing on pricing for drugs with high sales volumes, ensuring that MAC lists include prices for all forms and dosages of listed drug entities, and collaborating with other States or the Federal Government on MAC list operations. PMID:15229994

48 CFR 242.7000 - Contractor business system deficiencies.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contractor business system... Business Systems 242.7000 Contractor business system deficiencies. (a) Definitions. As used in this subpart— Acceptable contractor business systems and contractor business systems are defined in the clause at 252.242...

48 CFR 242.7000 - Contractor business system deficiencies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contractor business system... Business Systems 242.7000 Contractor business system deficiencies. (a) Definitions. As used in this subpart— Acceptable contractor business systems and contractor business systems are defined in the clause at 252.242...

48 CFR 242.7000 - Contractor business system deficiencies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contractor business system... BUSINESS SYSTEMS 242.7000 Contractor business system deficiencies. (a) Definitions. As used in this subpart— Acceptable contractor business systems and contractor business systems are defined in the clause at 252.242...

48 CFR 242.7000 - Contractor business system deficiencies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contractor business system... BUSINESS SYSTEMS 242.7000 Contractor business system deficiencies. (a) Definitions. As used in this subpart— Acceptable contractor business systems and contractor business systems are defined in the clause at 252.242...

48 CFR 1552.237-76 - Government-Contractor Relations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Government-Contractor... 1552.237-76 Government-Contractor Relations. As prescribed in 1537.110(g), insert the following clause: Government-Contractor Relations (JUN 1999) (a) The Government and the Contractor understand and agree that...

48 CFR 1552.237-76 - Government-Contractor Relations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Government-Contractor... 1552.237-76 Government-Contractor Relations. As prescribed in 1537.110(g), insert the following clause: Government-Contractor Relations (JUN 1999) (a) The Government and the Contractor understand and agree that...

48 CFR 1552.237-76 - Government-Contractor Relations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Government-Contractor... 1552.237-76 Government-Contractor Relations. As prescribed in 1537.110(g), insert the following clause: Government-Contractor Relations (JUN 1999) (a) The Government and the Contractor understand and agree that...

48 CFR 42.402 - Visits to contractors' facilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Visits to contractors... contractors' facilities. (a) Government personnel planning to visit a contractor's facility in connection with... positions, and security clearances. (2) Date and duration of visit. (3) Name and address of contractor and...

Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain.

PubMed

Greenslade, Jaimi H; Nayer, Robert; Parsonage, William; Doig, Shaela; Young, Joanna; Pickering, John W; Than, Martin; Hammett, Christopher; Cullen, Louise

2017-08-01

The Manchester Acute Coronary Syndromes (MACS) rule and the Troponin-only MACS (T-MACS) rule risk stratify patients with suspected acute coronary syndrome (ACS). This observational study sought to validate and compare the MACS and T-MACS rules for assessment of acute myocardial infarction (AMI). Prospectively collected data from twoEDs in Australia and New Zealand were analysed. Patients were assigned a probability of ACS based on the MACS and T-MACS rules, incorporating high-sensitivity troponin T, heart-type fatty acid-binding protein, ECG results and clinical symptoms. Patients were then deemed very low risk, low risk, intermediate or high risk if their MACS probability was less than 2%, between 2% and 5%, between 5% and 95% and greater than 95%, respectively. The primary endpoint was 30-day diagnosis of AMI. The secondary endpoint was 30-day major adverse cardiac event (MACE) including AMI, revascularisation or coronary stenosis (>70%). Sensitivity, specificity and predictive values were calculated to assess the accuracy of the MACS and T-MACS rules. Of the 1244 patients, 114 (9.2%) were diagnosed with AMI and 163 (13.1%) with MACE. The MACS and T-MACS rules categorised 133 (10.7%) and 246 (19.8%) patients, respectively, as very low risk and potentially suitable for early discharge from the ED. There was one false negative case for both rules making sensitivity 99.1% (95.2%-100%). MACS and T-MACS accurately risk stratify very low risk patients. The T-MACS rule would allow for more patients to be discharged early. The potential for missed MACE events means that further outpatient testing for coronary artery disease may be required for patients identified as very low risk. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

MacMouse. Developing Preschool Readiness Concepts and Skills with HyperCard and MacRecorder.

ERIC Educational Resources Information Center

Fitterman, L. Jeffrey

Through developments with the use of the "Apple Macintosh" computer, "HyperCard," and "MacRecorder," children in preschool handicapped programs are now capable of participating in appropriate computerized learning experiences. "HyperCard" allows educators to produce their own computerized instructional…

Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump

PubMed Central

Llabrés, Salomé; Neuberger, Arthur; Blaza, James N.; Bai, Xiao-chen; Okada, Ui; Murakami, Satoshi; van Veen, Hendrik W.; Zachariae, Ulrich; Scheres, Sjors H.W.; Luisi, Ben F.

2017-01-01

The MacA-MacB-TolC assembly of Escherichia coli is a transmembrane machine that spans the cell envelope and actively extrudes substrates, including macrolide antibiotics and polypeptide virulence factors. These transport processes are energized by the ATPase MacB, a member of the ATP-binding cassette (ABC) superfamily. We present an electron cryo-microscopy structure of the ABC-type tripartite assembly at near-atomic resolution. A hexamer of the periplasmic protein MacA bridges between a TolC trimer in the outer membrane and a MacB dimer in the inner membrane, generating a quaternary structure with a central channel for substrate translocation. A gating ring found in MacA is proposed to act as a one-way valve in substrate transport. The MacB structure features an atypical transmembrane domain (TMD) with a closely packed dimer interface and a periplasmic opening that is the likely portal for substrate entry from the periplasm, with subsequent displacement through an allosteric transport mechanism. PMID:28504659

41 CFR 109-38.301-1 - Contractors' use.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Contractors' use. 109-38...-38.301-1 Contractors' use. Heads of field organizations shall ensure that provisions of the FPMR concerning contractor use of Government motor vehicles are complied with by their designated contractors. ...

48 CFR 47.207-5 - Contractor responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

....207-5 Contractor responsibilities. Contractor responsibilities vary with the kinds of freight to be shipped and services required. The contracting officer shall specify clearly those service requirements... freight. The contracting officer shall insert the clause at 52.247-16, Contractor Responsibility for...

48 CFR 47.207-5 - Contractor responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

....207-5 Contractor responsibilities. Contractor responsibilities vary with the kinds of freight to be shipped and services required. The contracting officer shall specify clearly those service requirements... freight. The contracting officer shall insert the clause at 52.247-16, Contractor Responsibility for...

48 CFR 47.207-5 - Contractor responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

....207-5 Contractor responsibilities. Contractor responsibilities vary with the kinds of freight to be shipped and services required. The contracting officer shall specify clearly those service requirements... freight. The contracting officer shall insert the clause at 52.247-16, Contractor Responsibility for...

48 CFR 47.207-5 - Contractor responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

....207-5 Contractor responsibilities. Contractor responsibilities vary with the kinds of freight to be shipped and services required. The contracting officer shall specify clearly those service requirements... freight. The contracting officer shall insert the clause at 52.247-16, Contractor Responsibility for...

48 CFR 450.303-1 - Contractor requests.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contractor requests. 450.303-1 Section 450.303-1 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Contract Adjustments 450.303-1 Contractor requests. Contractor...

78 FR 11164 - Policy on Contractor Profits

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-15

... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System Policy on Contractor Profits AGENCY... Authorization Act for Fiscal Year 2013. Section 804, Department of Defense Policy on Contractor Profits... modifications to such guidelines that are necessary to ensure an appropriate link between contractor profit and...

48 CFR 970.5203-3 - Contractor's organization.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor's organization... for Management and Operating Contracts 970.5203-3 Contractor's organization. As prescribed in 970.0371-9, insert the following clause: Contractor's Organization (DEC 2000) (a) Organization chart. As...

48 CFR 46.301 - Contractor inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor inspection... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.301 Contractor inspection requirements. The contracting officer shall insert the clause at 52.246-1, Contractor Inspection Requirements, in solicitations...

C-MAC compared with direct laryngoscopy for intubation in patients with cervical spine immobilization: A manikin trial.

PubMed

Smereka, Jacek; Ladny, Jerzy R; Naylor, Amanda; Ruetzler, Kurt; Szarpak, Lukasz

2017-08-01

The aim of this study was to compare C-MAC videolaryngoscopy with direct laryngoscopy for intubation in simulated cervical spine immobilization conditions. The study was designed as a prospective randomized crossover manikin trial. 70 paramedics with <5years of medical experience participated in the study. The paramedics attempted to intubate manikins in 3 airway scenarios: normal airway without cervical immobilization (Scenario A); manual inline cervical immobilization (Scenario B); cervical immobilization using cervical extraction collar (Scenario C). Scenario A: Nearly all participants performed successful intubations with both MAC and C-MAC on the first attempt (95.7% MAC vs. 100% C-MAC), with similar intubation times (16.5s MAC vs. 18s C-MAC). Scenario B: The results with C-MAC were significantly better than those with MAC (p<0.05) for the time of intubation (23 s MAC vs. 19 s C-MAC), success of the first intubation attempt (88.6% MAC vs. 100% C-MAC), Cormack-Lehane grade, POGO score, severity of dental compression, device difficulty score, and preferred airway device. Scenario C: The results with C-MAC were significantly better than those with MAC (p<0.05) for all the analysed variables: success of the first attempt (51.4% MAC vs. 100% C-MAC), overall success rate, intubation time (27 s MAC vs. 20.5 s C-MAC), Cormack-Lehane grade, POGO score, dental compression, device difficulty score and the preferred airway device. The C-MAC videolaryngoscope is an excellent alternative to the MAC laryngoscope for intubating manikins with cervical spine immobilization. Copyright © 2017 Elsevier Inc. All rights reserved.

Discriminative validity of the MacAndrew Alcoholism Scale with Cluster B personality disorders.

PubMed

Smith, S R; Hilsenroth, M J

2001-06-01

This study was designed to assess the ability of the Minnesota Multiphasic Personality Inventory (MMPI-2) MacAndrew Alcoholism Scale (MAC-R) to differentiate between outpatients with personality disorders with Substance-Related Disorders (SRDs) and without SRDs. MMPI-2 validity, clinical, and MAC-R scale scores were compared in an SRD Cluster B group (comprised of Narcissistic, Antisocial, Borderline, and Histrionic; n = 15), a non-SRD Cluster B group (n = 33), and a non-SRD group with personality disorders from Clusters A and C (n = 18). Results revealed that the substance-abusing Cluster B group scored significantly higher on the MAC-R ( p <.0001) as well as the Psychopathic Deviate scale ( p <.01). Dimensional analyses illustrated that MAC-R scores were related to the presence of an SRD diagnosis (rpb =.70, p <.0001) and diagnostic criteria for Antisocial Personality Disorder (r =.60, p <.0001). Stepwise regression revealed that (in order of magnitude) the presence of a substance-abuse diagnosis followed by diagnostic criteria for Antisocial and Histrionic Personality Disorders were most related to MAC-R scores (R =.78, R(2) =.60). This indicates that the MAC-R may be more related to the presence of an SRD than has been suggested, and when used in outpatient settings as MacAndrew (1965) intended, the MAC-R may be useful as a screening device for assessing SRD among outpatients with Axis II psychopathology.

48 CFR 923.102 - Applicability to contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractors. 923.102 Section 923.102 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC... 923.102 Applicability to contractors. Many of the Department's major facilities are operated by contractors. Provisions regarding those contracts may be found at Part 970 of this chapter. At other locations...

48 CFR 2427.305-2 - Follow-up by contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Follow-up by contractor....305-2 Follow-up by contractor. (b) Contractor reports. Contractors shall complete and submit to the... Contracting Officer shall send the form to those contractors whose contract work may have required the...

20 CFR 670.985 - What happens if a center operator, screening and admissions contractor or other service provider...

Code of Federal Regulations, 2010 CFR

2010-04-01

... LABOR THE JOB CORPS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Administrative and Management..., including a screening and admissions contractor; (2) Changing the management staff of a center; (3) Changing...

Interaction between maropitant and carprofen on sparing of the minimum alveolar concentration for blunting adrenergic response (MAC-BAR) of sevoflurane in dogs

PubMed Central

FUKUI, Sho; OOYAMA, Norihiko; TAMURA, Jun; UMAR, Mohammed Ahmed; ISHIZUKA, Tomohito; ITAMI, Takaharu; MIYOSHI, Kenjiro; SANO, Tadashi; YAMASHITA, Kazuto

2017-01-01

Maropitant, a neurokinin-1 receptor antagonist, may provide analgesic effects by blocking pharmacological action of substance P. Carprofen is a non-steroidal anti-inflammatory drug commonly used for pain control in dogs. The purpose of this study was to evaluate the effect of a combination of maropitant and carprofen on the minimum alveolar concentration for blunting adrenergic response (MAC-BAR) of sevoflurane in dogs. Six healthy adult beagle dogs were anesthetized with sevoflurane four times with a minimum of 7-day washout period. On each occasion, maropitant (1 mg/kg) alone, carprofen (4 mg/kg) alone, a combination of maropitant (1 mg/kg) and carprofen (4 mg/kg), or saline (0.1 ml/kg) was subcutaneously administered at 1 hr prior to the first electrical stimulation for the sevoflurane MAC-BAR determination. The sevoflurane MAC-BAR was significantly reduced by maropitant alone (2.88 ± 0.73%, P=0.010), carprofen alone (2.96 ± 0.38%, P=0.016) and the combination (2.81 ± 0.51%, P=0.0003), compared with saline (3.37 ± 0.56%). There was no significant difference in the percentage of MAC-BAR reductions between maropitant alone, carprofen alone and the combination. The administration of maropitant alone and carprofen alone produced clinically significant sparing effects on the sevoflurane MAC-BAR in dogs. However, the combination of maropitant and carprofen did not produce any additive effect on the sevoflurane MAC-BAR reduction. Anesthetic premedication with a combination of maropitant and carprofen may not provide any further sparing effect on anesthetic requirement in dogs. PMID:28111373

Interaction between maropitant and carprofen on sparing of the minimum alveolar concentration for blunting adrenergic response (MAC-BAR) of sevoflurane in dogs.

PubMed

Fukui, Sho; Ooyama, Norihiko; Tamura, Jun; Umar, Mohammed Ahmed; Ishizuka, Tomohito; Itami, Takaharu; Miyoshi, Kenjiro; Sano, Tadashi; Yamashita, Kazuto

2017-03-18

Maropitant, a neurokinin-1 receptor antagonist, may provide analgesic effects by blocking pharmacological action of substance P. Carprofen is a non-steroidal anti-inflammatory drug commonly used for pain control in dogs. The purpose of this study was to evaluate the effect of a combination of maropitant and carprofen on the minimum alveolar concentration for blunting adrenergic response (MAC-BAR) of sevoflurane in dogs. Six healthy adult beagle dogs were anesthetized with sevoflurane four times with a minimum of 7-day washout period. On each occasion, maropitant (1 mg/kg) alone, carprofen (4 mg/kg) alone, a combination of maropitant (1 mg/kg) and carprofen (4 mg/kg), or saline (0.1 ml/kg) was subcutaneously administered at 1 hr prior to the first electrical stimulation for the sevoflurane MAC-BAR determination. The sevoflurane MAC-BAR was significantly reduced by maropitant alone (2.88 ± 0.73%, P=0.010), carprofen alone (2.96 ± 0.38%, P=0.016) and the combination (2.81 ± 0.51%, P=0.0003), compared with saline (3.37 ± 0.56%). There was no significant difference in the percentage of MAC-BAR reductions between maropitant alone, carprofen alone and the combination. The administration of maropitant alone and carprofen alone produced clinically significant sparing effects on the sevoflurane MAC-BAR in dogs. However, the combination of maropitant and carprofen did not produce any additive effect on the sevoflurane MAC-BAR reduction. Anesthetic premedication with a combination of maropitant and carprofen may not provide any further sparing effect on anesthetic requirement in dogs.

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 6 Domestic Security 1 2012-01-01 2012-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 6 Domestic Security 1 2013-01-01 2013-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

32 CFR 989.23 - Contractor prepared documents.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Contractor prepared documents. 989.23 Section... PROTECTION ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) § 989.23 Contractor prepared documents. All Air Force... should reflect on the cover sheet they are an Air Force document. Contractor preparation information...

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

Adaptive low-power listening MAC protocol based on transmission rates.

PubMed

Hwang, Kwang-il; Yi, Gangman

2014-01-01

Even though existing low-power listening (LPL) protocols have enabled ultra-low-power operation in wireless sensor networks (WSN), they do not address trade-off between energy and delay, since they focused only on energy aspect. However, in recent years, a growing interest in various WSN applications is requiring new design factors, such as minimum delay and higher reliability, as well as energy efficiency. Therefore, in this paper we propose a novel sensor multiple access control (MAC) protocol, transmission rate based adaptive low-power listening MAC protocol (TRA-MAC), which is a kind of preamble-based LPL but is capable of controlling preamble sensing cycle adaptively to transmission rates. Through experiments, it is demonstrated that TRA-MAC enables LPL cycle (LC) and preamble transmission length to adapt dynamically to varying transmission rates, compensating trade-off between energy and response time.

42 CFR 455.202 - Limitation on contractor liability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Limitation on contractor liability. 455.202 Section... § 455.202 Limitation on contractor liability. (a) A program contractor, a person, or an entity employed... contractor will not be held to have violated any criminal law and will not be held liable in any civil action...

[Eighty cases of monitored anesthesia care (MAC) for inguinal hernia repairs using tumescent local anesthesia (TLA)].

PubMed

Adachi, Koko; Kameyama, Eri; Yamada, Masahiro; Nakamura, Tadaho; Uchida, Kentaroh; Hayasaka, Tomoko

2011-10-01

This paper discusses the efficacy and difficulty of the management of monitored anesthesia care (MAC) for inguinal hernia repairs using tumescent local anesthesia(TLA). Eighty patients were retrospectively divided into four groups (all n = 20) according to the drugs used; group P (propofol), group PF (propofol and fentanyl), group PFM (propofol, fentanyl and midazolam), group PR (propofol and remifentanyl). The four groups were analyzed in terms of the applied dose, airway use, wake-up test to determine whether hernia was repaired, postoperative pain and nausea. More propofol was administered in group P than in group PFM and PR. Although, airway was used for nine patients, there was no difference between the four groups. Postoperative pain and nausea also do not differ between the groups. One patient in group P showed unsuccessful repair with wake-up test. MAC shows a beneficial effect on inguinal hernia repairs under TLA. The rate of airway use was as high as eleven percent, and maintenance of the patients' airway requires attention. In terms of wake-up test, propofol combined with opioid administration may be more effective than propofol administration alone. There was no significant difference between the groups in pain and nausea, regardless at the use of fentanyl or remifentanil.

Functional characterization of the copper transcription factor AfMac1 from Aspergillus fumigatus.

PubMed

Park, Yong-Sung; Kim, Tae-Hyoung; Yun, Cheol-Won

2017-07-03

Although copper functions as a cofactor in many physiological processes, copper overload leads to harmful effects in living cells. Thus, copper homeostasis is tightly regulated. However, detailed copper metabolic pathways have not yet been identified in filamentous fungi. In this report, we investigated the copper transcription factor AfMac1 ( A spergillus f umigatus Mac1 homolog) and identified its regulatory mechanism in A. fumigatus AfMac1 has domains homologous to the DNA-binding and copper-binding domains of Mac1 from Saccharomyces cerevisiae , and AfMac1 efficiently complemented Mac1 in S. cerevisiae Expression of Afmac1 resulted in CTR1 up-regulation, and mutation of the DNA-binding domain of Afmac1 failed to activate CTR1 expression in S. cerevisiae The Afmac1 deletion strain of A. fumigatus failed to grow in copper-limited media, and its growth was restored by introducing ctrC We found that AfMac1 specifically bound to the promoter region of ctrC based on EMSA. The AfMac1-binding motif 5'-TGTGCTCA-3' was identified from the promoter region of ctrC , and the addition of mutant ctrC lacking the AfMac1-binding motif failed to up-regulate ctrC in A. fumigatus Furthermore, deletion of Afmac1 significantly reduced strain virulence and activated conidial killing activity by neutrophils and macrophages. Taken together, these results suggest that AfMac1 is a copper transcription factor that regulates cellular copper homeostasis in A. fumigatus . © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

76 FR 20350 - Farm Credit Administration Board; Sunshine Act; Regular Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-12

.... New Business Operating and Strategic Business Planning--Proposed Rule Farmer Mac Risk-Based Capital... business. FOR FURTHER INFORMATION CONTACT: Dale L. Aultman, Secretary to the Farm Credit Administration...

18 CFR 3b.4 - Government contractors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Government contractors. 3b.4 Section 3b.4 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION... PERSONAL INFORMATION General § 3b.4 Government contractors. Systems of records operated by a contractor...

10 CFR 436.32 - Qualified contractors lists.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Qualified contractors lists. 436.32 Section 436.32 Energy... Procedures for Energy Savings Performance Contracting § 436.32 Qualified contractors lists. (a) DOE shall... energy savings performance contracts. (c) DOE may remove a firm from DOE's list of qualified contractors...

18 CFR 3b.4 - Government contractors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Government contractors. 3b.4 Section 3b.4 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION... PERSONAL INFORMATION General § 3b.4 Government contractors. Systems of records operated by a contractor...

Steven MacCall: Winner of LJ's 2010 Teaching Award

ERIC Educational Resources Information Center

Berry, John N., III

2010-01-01

This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

20 CFR 653.104 - Services to MSFW family members, farm labor contractors, and crew members.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Services to MSFW family members, farm labor contractors, and crew members. 653.104 Section 653.104 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR SERVICES OF THE EMPLOYMENT SERVICE SYSTEM Services for Migrant and Seasonal...

48 CFR 1552.237-76 - Government-Contractor Relations.

Code of Federal Regulations, 2014 CFR

2014-10-01

...: Government-Contractor Relations (JUN 1999) (a) The Government and the Contractor understand and agree that... event the notice is inadequate to make a decision, advise the Contractor what additional information is...

48 CFR 1552.237-76 - Government-Contractor Relations.

Code of Federal Regulations, 2012 CFR

2012-10-01

...: Government-Contractor Relations (JUN 1999) (a) The Government and the Contractor understand and agree that... event the notice is inadequate to make a decision, advise the Contractor what additional information is...

General practitioners and the independent contractor status

PubMed Central

Gray, D. J. Pereira

1977-01-01

Primary medical care can be provided either by a bureaucratic hierarchical organization or alternatively by independent contractors. Most members of the caring professions in medicine, nursing, and social work are employed in bureaucracies, whereas general medical practitioners, general dental practitioners, opticians, and pharmacists are independent contractors. The independent contractor status has recently been heavily attacked from within the medical and nursing professions, and also from outside. It has been suggested that contracting for services is an inappropriate and anomalous way of arranging medical care, which should now be stopped. However, this process of contracting for services can be analysed, using perspectives from some of the behavioural sciences, to reveal hidden depths in the independent contractor status which suggest that the provision of primary medical care is best carried out by independent contractors. PMID:616865

Comparative study of MacCormack and TVD MacCormack schemes for three-dimensional separation at wing/body junctions in supersonic flows

NASA Technical Reports Server (NTRS)

Lakshmanan, Balakrishnan; Tiwari, Surendra N.

1992-01-01

A robust, discontinuity-resolving TVD MacCormack scheme containing no dependent parameters requiring adjustment is presently used to investigate the 3D separation of wing/body junction flows at supersonic speeds. Many production codes employing MacCormack schemes can be adapted to use this method. A numerical simulation of laminar supersonic junction flow is found to yield improved separation location predictions, as well as the axial velocity profiles in the separated flow region.

Medicaid integrity program; limitation on contractor liability. Final rule.

PubMed

2007-11-30

The Medicaid Integrity Program (the Program) provides that the Secretary promote the integrity of the Medicaid program by entering into contracts with contractors that will review the actions of individuals or entities furnishing items or services (whether fee-for-service, risk, or other basis) for which payment may be made under an approved State plan and/or any waiver of the plan approved under section 1115 of the Social Security Act; audit claims for payment of items or services furnished, or administrative services furnished, under a State plan; identify overpayments of individuals or entities receiving Federal funds; and educate providers of services, managed care entities, beneficiaries, and other individuals with respect to payment integrity and quality of care. This final rule will provide for limitations on a contractor's liability while performing these services under the Program. The final rule will, to the extent possible, employ the same or comparable standards and other substantive and procedural provisions as are contained in section 1157 (Limitation on Liability) of the Social Security Act.

41 CFR 60-741.68 - Reinstatement of ineligible contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ineligible contractors. 60-741.68 Section 60-741.68 Public Contracts and Property Management Other Provisions..., DEPARTMENT OF LABOR 741-AFFIRMATIVE ACTION AND NONDISCRIMINATION OBLIGATIONS OF CONTRACTORS AND... Reinstatement of ineligible contractors. (a) Application for reinstatement. A contractor debarred from further...

41 CFR 60-300.68 - Reinstatement of ineligible contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ineligible contractors. 60-300.68 Section 60-300.68 Public Contracts and Property Management Other Provisions..., DEPARTMENT OF LABOR 300-AFFIRMATIVE ACTION AND NONDISCRIMINATION OBLIGATIONS OF CONTRACTORS AND... ineligible contractors. (a) Application for reinstatement. A contractor debarred from further contracts for...

41 CFR 60-250.68 - Reinstatement of ineligible contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ineligible contractors. 60-250.68 Section 60-250.68 Public Contracts and Property Management Other Provisions..., DEPARTMENT OF LABOR 250-AFFIRMATIVE ACTION AND NONDISCRIMINATION OBLIGATIONS OF CONTRACTORS AND... ineligible contractors. (a) Application for reinstatement. A contractor debarred from further contracts for...

Geospatial Multi-Agency Coordination (GeoMAC) wildland fire perimeters, 2008

USGS Publications Warehouse

Walters, Sandra P.; Schneider, Norma J.; Guthrie, John D.

2011-01-01

The Geospatial Multi-Agency Coordination (GeoMAC) has been collecting and storing data on wildland fire perimeters since August 2000. The dataset presented via this U.S. Geological Survey Data Series product contains the GeoMAC wildland fire perimeter data for the calendar year 2008, which are based upon input from incident intelligence sources, Global Positioning System (GPS) data, and infrared (IR) imagery. Wildland fire perimeter data are obtained from the incidents, evaluated for completeness and accuracy, and processed to reflect consistent field names and attributes. After a quality check, the perimeters are loaded to GeoMAC databases, which support the GeoMAC Web application for access by wildland fire managers and the public. The wildland fire perimeters are viewed through the Web application. The data are subsequently archived according to year and state and are made available for downloading through the Internet in shapefile and Keyhole Markup Language (KML) format. These wildland fire perimeter data are also retained for historical, planning, and research purposes. The datasets that pertain to this report can be found on the Rocky Mountain Geographic Science Center HTTP site at http://rmgsc.cr.usgs.gov/outgoing/GeoMAC/historic_fire_data/. The links are also provided on the sidebar.

Mac OS X for Astronomy

NASA Astrophysics Data System (ADS)

Pierfederici, F.; Pirzkal, N.; Hook, R. N.

Mac OS X is the new Unix based version of the Macintosh operating system. It combines a high performance DisplayPDF user interface with a standard BSD UNIX subsystem and provides users with simultaneous access to a broad range of applications which were not previously available on a single system such as Microsoft Office and Adobe Photoshop, as well as legacy X11-based scientific tools and packages like IRAF, SuperMongo, MIDAS, etc. The combination of a modern GUI layered on top of a familiar UNIX environment paves the way for new, more flexible and powerful astronomical tools to be developed while assuring compatibility with already existing, older programs. In this paper, we outline the strengths of the Mac OS X platform in a scientific environment, astronomy in particular, and point to the numerous astronomical software packages available for this platform; most notably the Scisoft collection which we have compiled.

41 CFR 60-1.31 - Reinstatement of ineligible contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ineligible contractors. 60-1.31 Section 60-1.31 Public Contracts and Property Management Other Provisions..., DEPARTMENT OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS General Enforcement; Compliance Review and Complaint Procedure § 60-1.31 Reinstatement of ineligible contractors. A contractor debarred from...

48 CFR 952.251-70 - Contractor employee travel discounts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor employee travel... Contractor employee travel discounts. As prescribed in 951.7002, insert the following clause: Contractor Employee Travel Discounts (AUG 2009) (a) The Contractor shall take advantage of travel discounts offered to...

48 CFR 245.608 - Screening of contractor inventory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Screening of contractor inventory. 245.608 Section 245.608 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Disposal of Contractor Inventory 245.608 Screening of contractor inventory. ...

42 CFR 423.2110 - MAC reviews on its own motion.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false MAC reviews on its own motion. 423.2110 Section 423.2110 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review...

48 CFR 1553.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor qualifications. 1553.209 Section 1553.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS FORMS Prescription of Forms 1553.209 Contractor qualifications. ...

MAC/GMC 4.0 User's Manual: Keywords Manual. Volume 2

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Arnold, Steven M.

2002-01-01

This document is the second volume in the three volume set of User's Manuals for the Micromechanics Analysis Code with Generalized Method of Cells Version 4.0 (MAC/GMC 4.0). Volume 1 is the Theory Manual, this document is the Keywords Manual, and Volume 3 is the Example Problem Manual. MAC/GMC 4.0 is a composite material and laminate analysis software program developed at the NASA Glenn Research Center. It is based on the generalized method of cells (GMC) micromechanics theory, which provides access to the local stress and strain fields in the composite material. This access grants GMC the ability to accommodate arbitrary local models for inelastic material behavior and various types of damage and failure analysis. MAC/GMC 4.0 has been built around GMC to provide the theory with a user-friendly framework, along with a library of local inelastic, damage, and failure models. Further, applications of simulated thermo-mechanical loading, generation of output results, and selection of architectures to represent the composite material have been automated in MAC/GMC 4.0. Finally, classical lamination theory has been implemented within MAC/GMC 4.0 wherein GMC is used to model the composite material response of each ply. Consequently, the full range of GMC composite material capabilities is available for analysis of arbitrary laminate configurations as well. This volume describes the basic information required to use the MAC/GMC 4.0 software, including a 'Getting Started' section, and an in-depth description of each of the 22 keywords used in the input file to control the execution of the code.

Minimum alveolar concentration (MAC) for sevoflurane and xenon at normothermia and hypothermia in newborn pigs.

PubMed

Liu, X; Dingley, J; Elstad, M; Scull-Brown, E; Steen, P A; Thoresen, M

2013-05-01

Neuroprotection from therapeutic hypothermia increases when combined with the anaesthetic gas xenon in animal studies. A clinical feasibility study of the combined treatment has been successfully undertaken in asphyxiated human term newborns. It is unknown whether xenon alone would be sufficient for sedation during hypothermia eliminating or reducing the need for other sedative or analgesic infusions in ventilated sick infants. Minimum alveolar concentration (MAC) of xenon is unknown in any neonatal species. Eight newborn pigs were anaesthetised with sevoflurane alone and then sevoflurane plus xenon at two temperatures. Pigs were randomised to start at either 38.5°C or 33.5°C. MAC for sevoflurane was determined using the claw clamp technique at the preset body temperature. For xenon MAC determination, a background of 0.5 MAC sevoflurane was used, and 60% xenon added to the gas mixture. The relationship between sevoflurane and xenon MAC is assumed to be additive. Xenon concentrations were changed in 5% steps until a positive clamp reaction was noted. Pigs' temperature was changed to the second target, and two MAC determinations for sevoflurane and 0.5 MAC sevoflurane plus xenon were repeated. MAC for sevoflurane was 4.1% [95% confidence interval (CI): 3.65-4.50] at 38.5°C and 3.05% (CI: 2.63-3.48) at 33.5°C, a significant reduction. MAC for xenon was 120% at 38.5°C and 116% at 33.5°C, not different. In newborn swine sevoflurane, MAC was temperature dependent, while xenon MAC was independent of temperature. There was large individual variability in xenon MAC, from 60% to 120%. © 2013 The Acta Anaesthesiologica Scandinavica Foundation.

48 CFR 1852.209-72 - Composition of the contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor. 1852.209-72 Section 1852.209-72 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.209-72 Composition of the contractor. As prescribed in 1809.670, insert the following clause: Composition of the Contractor (DEC 1988) If the Contractor is comprised of more than one legal...

40 CFR 35.938-6 - Progress payments to contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Progress payments to contractors. 35... § 35.938-6 Progress payments to contractors. (a) Policy. EPA policy is that, except as State law otherwise provides, grantees should make prompt progress payments to prime contractors and prime contractors...

48 CFR 53.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor qualifications. 53.209 Section 53.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.209 Contractor qualifications. ...

48 CFR 1552.209-76 - Contractor performance evaluations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor performance... 1552.209-76 Contractor performance evaluations. As prescribed in section 1509.170-1, insert the following clause in all applicable solicitations and contracts. Contractor Performance Evaluations (OCT 2002...

48 CFR 8.406-7 - Contractor Performance Evaluation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor Performance... ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Federal Supply Schedules 8.406-7 Contractor Performance Evaluation. Ordering activities must prepare an evaluation of contractor performance for each...

48 CFR 2936.201 - Evaluation of contractor performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Evaluation of contractor... Construction 2936.201 Evaluation of contractor performance. The HCA must establish procedures to evaluate construction contractor performance and prepare performance reports as required by FAR 36.201. ...

48 CFR 32.909 - Contractor inquiries.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor inquiries. 32.909 Section 32.909 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Prompt Payment 32.909 Contractor inquiries. (a) Direct questions...

Dolphin natures, human virtues: MacIntyre and ethical naturalism.

PubMed

Glackin, Shane Nicholas

2008-09-01

Can biological facts explain human morality? Aristotelian 'virtue' ethics has traditionally assumed so. In recent years Alasdair MacIntyre has reintroduced a form of Aristotle's 'metaphysical biology' into his ethics. He argues that the ethological study of dependence and rationality in other species--dolphins in particular--sheds light on how those same traits in the typical lives of humans give rise to the moral virtues. However, some goal-oriented dolphin behaviour appears both dependent and rational in the precise manner which impresses MacIntyre, yet anything but ethically 'virtuous'. More damningly, dolphin ethologists consistently refuse to evaluate such behaviour in the manner MacIntyre claims is appropriate to moral judgement. In light of this, I argue that virtues--insofar as they name a biological or ethological category--do not name a morally significant one.

28 CFR 115.132 - Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... notification of the agency's zero-tolerance policy. 115.132 Section 115.132 Judicial Administration DEPARTMENT... and Education § 115.132 Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy. (a) During the intake process, employees shall notify all detainees of the agency's zero...

28 CFR 115.132 - Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... notification of the agency's zero-tolerance policy. 115.132 Section 115.132 Judicial Administration DEPARTMENT... and Education § 115.132 Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy. (a) During the intake process, employees shall notify all detainees of the agency's zero...

28 CFR 115.132 - Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... notification of the agency's zero-tolerance policy. 115.132 Section 115.132 Judicial Administration DEPARTMENT... and Education § 115.132 Detainee, contractor, and inmate worker notification of the agency's zero-tolerance policy. (a) During the intake process, employees shall notify all detainees of the agency's zero...

48 CFR 970.5244-1 - Contractor purchasing system.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for Management and Operating Contracts 970.5244-1 Contractor purchasing system. As prescribed in 970... management system. The Contractor's approved purchasing system and methods shall include the requirements set... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contractor purchasing...

48 CFR 2152.215-70 - Contractor records retention.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor records... PRECONTRACT PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 2152.215-70 Contractor records retention. As prescribed in 2115.071, insert the following clause: Contractor Records Retention (OCT 2005...

75 FR 69037 - Medicaid Program; Recovery Audit Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

... [CMS-6034-P] RIN 0938-AQ19 Medicaid Program; Recovery Audit Contractors AGENCY: Centers for Medicare... Recovery Audit Contractors (Medicaid RACs) and the payment methodology for State payments to Medicaid RACs... RACs coordinate with other contractors and entities auditing Medicaid providers and with State and...

48 CFR 3036.201 - Evaluation of contractor performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Evaluation of contractor performance. 3036.201 Section 3036.201 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY... contractor performance. (a)(2) Performance reports shall be prepared and entered into the Contractor...

48 CFR 36.506 - Superintendence by the contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor. 36.506 Section 36.506 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Superintendence by the contractor. The contracting officer shall insert the clause at 52.236-6, Superintendence by the Contractor, in solicitations and contracts when a fixed-price construction contract or a fixed...

48 CFR 2452.251-70 - Contractor employee travel.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor employee travel... 2452.251-70 Contractor employee travel. As prescribed in 2451.7001, insert the following clause in all cost-reimbursement solicitations and contracts involving travel: Contractor Employee Travel (OCT 1999...

76 FR 57807 - Medicaid Program; Recovery Audit Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... for Medicare & Medicaid Services 42 CFR Part 455 Medicaid Program; Recovery Audit Contractors; Final... 42 CFR Part 455 [CMS-6034-F] RIN 0938-AQ19 Medicaid Program; Recovery Audit Contractors AGENCY... costs of Medicaid Recovery Audit Contractors (Medicaid RACs) and the payment methodology for State...

48 CFR 1652.204-70 - Contractor records retention.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor records... of FEHBP Clauses 1652.204-70 Contractor records retention. As prescribed in 1604.705 the following clause will be inserted in all FEHB Program contracts. Contractor Records Retention (JUL 2005...

Interference Analysis Status and Plans for Aeronautical Mobile Airport Communications System (AeroMACS)

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Wilson, Jeffrey D.

2010-01-01

Interference issues related to the operation of an aeronautical mobile airport communications system (AeroMACS) in the C-Band (specifically 5091-5150 MHz) is being investigated. The issue of primary interest is co-channel interference from AeroMACS into mobile-satellite system (MSS) feeder uplinks. The effort is focusing on establishing practical limits on AeroMACS transmissions from airports so that the threshold of interference into MSS is not exceeded. The analyses are being performed with the software package Visualyse Professional, developed by Transfinite Systems Limited. Results with omni-directional antennas and plans to extend the models to represent AeroMACS more accurately will be presented. These models should enable realistic analyses of emerging AeroMACS designs to be developed from NASA Test Bed, RTCA 223, and European results.

77 FR 72905 - Pipeline Safety: Random Drug Testing Rate; Contractor MIS Reporting; and Obtaining DAMIS Sign-In...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... Drug and Alcohol Management Information System (DAMIS) to operators, but will make the user name and... DAMIS Sign-In Information AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT... testing information must be submitted for contractors performing or ready to perform covered functions...

48 CFR 1845.505-70 - Responsibilities of the property administrator.

Code of Federal Regulations, 2014 CFR

2014-10-01

... determines that all or a portion of a contractor's property management practices and processes do not afford... AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Support Government Property... the Government's acceptance of risk. (d) The property administrator shall review records and the...

48 CFR 1845.505-70 - Responsibilities of the property administrator.

Code of Federal Regulations, 2013 CFR

2013-10-01

... determines that all or a portion of a contractor's property management practices and processes do not afford... AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Support Government Property... the Government's acceptance of risk. (d) The property administrator shall review records and the...

48 CFR 1845.505-70 - Responsibilities of the property administrator.

Code of Federal Regulations, 2012 CFR

2012-10-01

... determines that all or a portion of a contractor's property management practices and processes do not afford... AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Support Government Property... the Government's acceptance of risk. (d) The property administrator shall review records and the...

48 CFR 46.105 - Contractor responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is responsible for carrying out its obligations under the contract by— (1) Controlling the quality of supplies or..., subassemblies, etc., have an acceptable quality control system; and (4) Maintaining substantiating evidence...

48 CFR 46.105 - Contractor responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is responsible for carrying out its obligations under the contract by— (1) Controlling the quality of supplies or..., subassemblies, etc., have an acceptable quality control system; and (4) Maintaining substantiating evidence...

48 CFR 46.105 - Contractor responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is responsible for carrying out its obligations under the contract by— (1) Controlling the quality of supplies or..., subassemblies, etc., have an acceptable quality control system; and (4) Maintaining substantiating evidence...

48 CFR 46.105 - Contractor responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is responsible for carrying out its obligations under the contract by— (1) Controlling the quality of supplies or..., subassemblies, etc., have an acceptable quality control system; and (4) Maintaining substantiating evidence...

48 CFR 253.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contractor qualifications. 253.209 Section 253.209 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS FORMS Prescription of Forms 253.209 Contractor qualifications. ...

Contractor and government - Teamwork and commitment

NASA Technical Reports Server (NTRS)

Griffin, G. D.

1985-01-01

Procedures being implemented at NASA to improve cooperation with contractors and increase productivity are reviewed from the NASA point of view. The goals of the U.S. space program for the coming 25 years are listed, and the importance of the commercial utilization of space in these plans is stressed. Consideration is given to the ongoing American Productivity Center White-Collar Productivity-Improvement Project, the implementation of the recommendations of the 1984 NASA/Contractor Conferences in present and future contracts, and the use of incentive contracts to create situations in which both NASA and the contractor benefit from increased productivity. Future plans call for increased industry responsibility in managing and operating the STS; steamlining of Shuttle operations; advanced design-to-cost procedures, increased commonality, better NASA-contractor communications, and more use of CAD/CAM and robotics for the Space Station; and accommodation of greatly expanded private investment and exploitation of space.

48 CFR 252.242-7005 - Contractor business systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contractor business... of Provisions And Clauses 252.242-7005 Contractor business systems. As prescribed in 242.7001, use the following clause: Contractor Business Systems (FEB 2012) (a) This clause only applies to covered...

48 CFR 252.242-7005 - Contractor business systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contractor business... of Provisions And Clauses 252.242-7005 Contractor business systems. As prescribed in 242.7001, use the following clause: Contractor Business Systems (FEB 2012) (a) This clause only applies to covered...

48 CFR 252.242-7005 - Contractor business systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contractor business... of Provisions And Clauses 252.242-7005 Contractor business systems. As prescribed in 242.7001, use the following clause: CONTRACTOR BUSINESS SYSTEMS (MAY 2011) (a) Definitions. As used in this clause...

48 CFR 252.242-7005 - Contractor business systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contractor business... of Provisions And Clauses 252.242-7005 Contractor business systems. As prescribed in 242.7001, use the following clause: Contractor Business Systems (FEB 2012) (a) This clause only applies to covered...

48 CFR 53.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractors. 53.209-1 Section 53.209-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.209-1 Responsible prospective contractors. (a) SF 1403 (Rev. 9/88), Preaward Survey of Prospective Contractor (General). SF 1403 is authorized for...

30 CFR 874.16 - Contractor eligibility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Contractor eligibility. 874.16 Section 874.16 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR ABANDONED MINE LAND RECLAMATION GENERAL RECLAMATION REQUIREMENTS § 874.16 Contractor eligibility. To receive...

30 CFR 875.20 - Contractor eligibility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Contractor eligibility. 875.20 Section 875.20 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR ABANDONED MINE LAND RECLAMATION CERTIFICATION AND NONCOAL RECLAMATION § 875.20 Contractor eligibility. Every...

Contractor Motivation Theory and Applications.

DTIC Science & Technology

1981-03-01

Project Officer, Chief, Test and Evaluation Group , US Army Procurement Research Office, ALMC. BS, Aeronautical Engineering, University of Wyoming, 1963...Contractor Motivation Theory and Applications SEE DISTRIBUTION Inclosed is a copy of subject report for your use . This report describes the DOD contractor...motivation process and various areas for improvement. In particular, it identifies effective incentives that can be used and recommends policy that

Dependence of AeroMACS Interference on Airport Radiation Pattern Characteristics

NASA Technical Reports Server (NTRS)

Wilson, Jeffrey D.

2012-01-01

AeroMACS (Aeronautical Mobile Airport Communications System), which is based upon the IEEE 802.16e mobile wireless standard, is expected to be implemented in the 5091 to 5150 MHz frequency band. As this band is also occupied by Mobile Satellite Service (MSS) feeder uplinks, AeroMACS must be designed to avoid interference with this incumbent service. The aspects of AeroMACS operation that present potential interference are under analysis in order to enable the definition of standards that assure that such interference will be avoided. In this study, the cumulative interference power distribution at low earth orbit from AeroMACS transmitters at the 497 major airports in the contiguous United States was simulated with the Visualyse Professional software. The dependence of the interference power on the number of antenna beams per airport, gain patterns, and beam direction orientations was simulated. As a function of these parameters, the simulation results are presented in terms of the limitations on transmitter power required to maintain the cumulative interference power under the established threshold.

Dependence of AeroMACS Interference on Airport Radiation Pattern Characteristics

NASA Technical Reports Server (NTRS)

Wilson, Jeffrey D.

2012-01-01

AeroMACS (Aeronautical Mobile Airport Communications System), which is based upon the IEEE 802.16e mobile wireless standard, is expected to be implemented in the 5091-5150 MHz frequency band. As this band is also occupied by Mobile Satellite Service (MSS) feeder uplinks, AeroMACS must be designed to avoid interference with this incumbent service. The aspects of AeroMACS operation that present potential interference are under analysis in order to enable the definition of standards that assure that such interference will be avoided. In this study, the cumulative interference power distribution at low earth orbit from AeroMACS transmitters at the 497 major airports in the contiguous United States was simulated with the Visualyse Professional software. The dependence of the interference power on the number of antenna beams per airport, gain patterns, and beam direction orientations was simulated. As a function of these parameters, the simulation results are presented in terms of the limitations on transmitter power required to maintain the cumulative interference power under the established threshold.

20 CFR 655.19 - Job contractor filing requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false Job contractor filing requirements. 655.19... States (H-2B Workers) Application for Temporary Employment Certification Filing Procedures § 655.19 Job contractor filing requirements. (a) Provided that a job contractor and any employer-client are joint...

20 CFR 655.19 - Job contractor filing requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false Job contractor filing requirements. 655.19... States (H-2B Workers) Application for Temporary Employment Certification Filing Procedures § 655.19 Job contractor filing requirements. (a) Provided that a job contractor and any employer-client are joint...

20 CFR 655.19 - Job contractor filing requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Job contractor filing requirements. 655.19... States (H-2B Workers) Application for Temporary Employment Certification Filing Procedures § 655.19 Job contractor filing requirements. (a) Provided that a job contractor and any employer-client are joint...

32 CFR 516.21 - Litigation against government contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Litigation against government contractors. 516.21... government contractors. (a) General. A contract might require that the government reimburse a contractor (or... with the government requires reimbursement for adverse judgments or costs of the litigation, the SJA or...

7 CFR 3015.183 - Access to contractor records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Access to contractor records. 3015.183 Section 3015... contractor records. The Attachment 0 requires recipients to include in specified kinds of contracts a provision for access to the contractor's records by the recipient and the Federal government. The following...

4 CFR 75.1 - Contractors' and vendors' certificates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Contractors' and vendors' certificates. 75.1 Section 75.1... BASIC VOUCHERS AND INVOICES § 75.1 Contractors' and vendors' certificates. (a) The Government... bills and invoices of contractors and vendors, with the exception that carriers, or other corporations...

48 CFR 3052.204-71 - Contractor employee access.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Contractor employee access... CLAUSES Text of Provisions and Clauses 3052.204-71 Contractor employee access. As prescribed in (HSAR) 48...: Contractor Employee Access (JUN 2006) (a) “Sensitive Information,” as used in this Chapter, means any...

78 FR 51658 - Weighing, Feed, and Swine Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-21

... RIN 0580-AA99 Weighing, Feed, and Swine Contractors AGENCY: Grain Inspection, Packers and Stockyards... and swine contractors to poultry and swine production contract growers are based on accurate weighing... reweighing to add swine contractors to the list of firms that must comply, and adding feed to the list of...

Contractor Accounting, Reporting and Estimating (CARE).

DTIC Science & Technology

Contractor Accounting Reporting and Estimating (CARE) provides check lists that may be used as guides in evaluating the accounting system, financial reporting , and cost estimating capabilities of the contractor. Experience gained from the Management Review Technique was used as a basis for the check lists. (Author)

48 CFR 945.610-4 - Contractor inventory in foreign countries.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor inventory in... CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 945.610-4 Contractor inventory in foreign countries. Contractor inventory located in foreign countries...

41 CFR 109-43.302-50 - Utilization by designated contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... designated contractors. 109-43.302-50 Section 109-43.302-50 Public Contracts and Property Management Federal... Utilization by designated contractors. Heads of field organizations may authorize designated contractors to... Federal agency, provided the designated contractors have written policies and procedures. ...

49 CFR 10.27 - Government contractors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false Government contractors. 10.27 Section 10.27 Transportation Office of the Secretary of Transportation MAINTENANCE OF AND ACCESS TO RECORDS PERTAINING TO INDIVIDUALS Maintenance of Records § 10.27 Government contractors. When the Department provides by a contract...

49 CFR 10.27 - Government contractors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Government contractors. 10.27 Section 10.27 Transportation Office of the Secretary of Transportation MAINTENANCE OF AND ACCESS TO RECORDS PERTAINING TO INDIVIDUALS Maintenance of Records § 10.27 Government contractors. When the Department provides by a contract...

49 CFR 10.27 - Government contractors.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false Government contractors. 10.27 Section 10.27 Transportation Office of the Secretary of Transportation MAINTENANCE OF AND ACCESS TO RECORDS PERTAINING TO INDIVIDUALS Maintenance of Records § 10.27 Government contractors. When the Department provides by a contract...

49 CFR 10.27 - Government contractors.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Government contractors. 10.27 Section 10.27 Transportation Office of the Secretary of Transportation MAINTENANCE OF AND ACCESS TO RECORDS PERTAINING TO INDIVIDUALS Maintenance of Records § 10.27 Government contractors. When the Department provides by a contract...

Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs)

PubMed Central

Shetty, Dinesh; Kim, Yong Joon; Shim, Hyunsuk; Snyder, James P.

2015-01-01

Curcumin is a natural product with several thousand years of heritage. Its traditional Asian application to human ailments has been subjected in recent decades to worldwide pharmacological, biochemical and clinical investigations. Curcumin’s Achilles heel lies in its poor aqueous solubility and rapid degradation at pH ~ 7.4. Researchers have sought to unlock curcumin’s assets by chemical manipulation. One class of molecules under scrutiny are the monocarbonyl analogs of curcumin (MACs). A thousand plus such agents have been created and tested primarily against cancer and inflammation. The outcome is clear. In vitro, MACs furnish a 10–20 fold potency gain vs. curcumin for numerous cancer cell lines and cellular proteins. Similarly, MACs have successfully demonstrated better pharmacokinetic (PK) profiles in mice and greater tumor regression in cancer xenografts in vivo than curcumin. The compounds reveal limited toxicity as measured by murine weight gain and histopathological assessment. To our knowledge, MAC members have not yet been monitored in larger animals or humans. However, Phase 1 clinical trials are certainly on the horizon. The present review focuses on the large and evolving body of work in cancer and inflammation, but also covers MAC structural diversity and early discovery for treatment of bacteria, tuberculosis, Alzheimer’s disease and malaria. PMID:25547726

Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia.

PubMed

Williams, D C; Brosnan, R J; Fletcher, D J; Aleman, M; Holliday, T A; Tharp, B; Kass, P H; LeCouteur, R A; Steffey, E P

2016-01-01

The effects of anesthesia on the equine electroencephalogram (EEG) after administration of various drugs for sedation, induction, and maintenance are known, but not that the effect of inhaled anesthetics alone for EEG recording. To determine the effects of isoflurane and halothane, administered as single agents at multiple levels, on the EEG and quantitative EEG (qEEG) of normal horses. Six healthy horses. Prospective study. Digital EEG with video and quantitative EEG (qEEG) were recorded after the administration of one of the 2 anesthetics, isoflurane or halothane, at 3 alveolar doses (1.2, 1.4 and 1.6 MAC). Segments of EEG during controlled ventilation (CV), spontaneous ventilation (SV), and with peroneal nerve stimulation (ST) at each MAC multiple for each anesthetic were selected, analyzed, and compared. Multiple non-EEG measurements were also recorded. Specific raw EEG findings were indicative of changes in the depth of anesthesia. However, there was considerable variability in EEG between horses at identical MAC multiples/conditions and within individual horses over segments of a given epoch. Statistical significance for qEEG variables differed between anesthetics with bispectral index (BIS) CV MAC and 95% spectral edge frequency (SEF95) SV MAC differences in isoflurane only and median frequency (MED) differences in SV MAC with halothane only. Unprocessed EEG features (background and transients) appear to be beneficial for monitoring the depth of a particular anesthetic, but offer little advantage over the use of changes in mean arterial pressure for this purpose. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

48 CFR 52.230-6 - Administration of Cost Accounting Standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Clauses 52.230-6 Administration of Cost Accounting Standards. As prescribed in 30.201-4(d)(1), insert the following clause: Administration of Cost Accounting Standards (JUN 2010) For the purpose of administering the Cost Accounting Standards (CAS) requirements under this contract, the Contractor shall take the...

Geochemistry and petrography of the MacAlpine Hills lunar meteorites

NASA Technical Reports Server (NTRS)

Lindstrom, Marilyn M.; Mckay, David S.; Wentworth, Susan J.; Martinez, Rene R.; Mittlefehldt, David W.; Wang, Ming-Sheng; Lipschutz, Michael E.

1991-01-01

MacAlpine Hills 88104 and 88105, anorthositic lunar meteorites recovered form the same area in Antartica, are characterized. Petrographic studies show that MAC88104/5 is a polymict breccia dominated by impact melt clasts. It is better classified as a fragmental breccia than a regolith breccia. The bulk composition is ferroan and highly aluminous (Al2O3-28 percent).

Channel MAC Protocol for Opportunistic Communication in Ad Hoc Wireless Networks

NASA Astrophysics Data System (ADS)

Ashraf, Manzur; Jayasuriya, Aruna; Perreau, Sylvie

2008-12-01

Despite significant research effort, the performance of distributed medium access control methods has failed to meet theoretical expectations. This paper proposes a protocol named "Channel MAC" performing a fully distributed medium access control based on opportunistic communication principles. In this protocol, nodes access the channel when the channel quality increases beyond a threshold, while neighbouring nodes are deemed to be silent. Once a node starts transmitting, it will keep transmitting until the channel becomes "bad." We derive an analytical throughput limit for Channel MAC in a shared multiple access environment. Furthermore, three performance metrics of Channel MAC—throughput, fairness, and delay—are analysed in single hop and multihop scenarios using NS2 simulations. The simulation results show throughput performance improvement of up to 130% with Channel MAC over IEEE 802.11. We also show that the severe resource starvation problem (unfairness) of IEEE 802.11 in some network scenarios is reduced by the Channel MAC mechanism.

Detomidine reduces isoflurane anesthetic requirement (MAC) in horses.

PubMed

Steffey, Eugene P; Pascoe, Peter J

2002-10-01

To quantitate the dose- and time-related magnitude of the anesthetic sparing effect of, and selected physiological responses to detomidine during isoflurane anesthesia in horses. Randomized cross-over study. Three, healthy, young adult horses weighing 485 ± 14 kg. Horses were anesthetized on two occasions to determine the minimum alveolar concentration (MAC) of isoflurane in O 2 and then to measure the anesthetic sparing effect (time-related MAC reduction) following IV detomidine (0.03 and 0.06 mg kg -1 ). Selected common measures of cardiopulmonary function, blood glucose and urinary output were also recorded. Isoflurane MAC was 1.44 ± 0.07% (mean ± SEM). This was reduced by 42.8 ± 5.4% and 44.8 ± 3.0% at 83 ± 23 and 125 ± 36 minutes, respectively, following 0.03 and 0.06 mg kg -1 , detomidine. The MAC reduction was detomidine dose- and time-dependent. There was a tendency for mild cardiovascular and respiratory depression, especially following the higher detomidine dose. Detomidine increased both blood glucose and urine flow; the magnitude of these changes was time- and dose-dependent CONCLUSIONS: Detomidine reduces anesthetic requirement for isoflurane and increases blood glucose concentration and urine flow in horses. These changes were dose- and time-related. The results imply potent anesthetic sparing actions by detomidine. The detomidine-related increased urine flow should be considered in designing anesthetic protocols for individual horses. Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

76 FR 37704 - Federal Acquisition Regulation; Documenting Contractor Performance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... Federal Acquisition Regulation; Documenting Contractor Performance AGENCY: Department of Defense (DoD..., and to require all past performance information be entered into the Contractor Performance Assessment... Contractor Performance Information. These changes provide Governmentwide standardized evaluation factors and...

Debarment and suspension. [of contractors

NASA Technical Reports Server (NTRS)

Whelan, Thomas J.

1987-01-01

The changing Government attitude toward contractor debarment and suspension is examined, with emphasis on the fact that the Government is more alert to fraud, waste, and abuse. Consideration is given to causes of debarment or suspension, procedures and due process hearings, settlement agreements, compliance programs, and recent related legislation. It is concluded that the change in the Government contracting environment in recent years should be sufficient incentive for contractors to monitor their operations more closely.

48 CFR 1852.242-73 - NASA contractor financial management reporting.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA contractor financial... Provisions and Clauses 1852.242-73 NASA contractor financial management reporting. As prescribed in 1842.7202, insert the following clause: NASA Contractor Financial Management Reporting (NOV 2004) (a) The Contractor...

48 CFR 1852.242-73 - NASA contractor financial management reporting.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA contractor financial... Provisions and Clauses 1852.242-73 NASA contractor financial management reporting. As prescribed in 1842.7202, insert the following clause: NASA Contractor Financial Management Reporting (NOV 2004) (a) The Contractor...

48 CFR 1852.242-73 - NASA contractor financial management reporting.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA contractor financial... Provisions and Clauses 1852.242-73 NASA contractor financial management reporting. As prescribed in 1842.7202, insert the following clause: NASA Contractor Financial Management Reporting (NOV 2004) (a) The Contractor...

48 CFR 1852.242-73 - NASA contractor financial management reporting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA contractor financial... Provisions and Clauses 1852.242-73 NASA contractor financial management reporting. As prescribed in 1842.7202, insert the following clause: NASA Contractor Financial Management Reporting (NOV 2004) (a) The Contractor...

4 CFR 83.19 - Government contractors.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Government contractors. 83.19 Section 83.19 Accounts GOVERNMENT ACCOUNTABILITY OFFICE RECORDS PRIVACY PROCEDURES FOR PERSONNEL RECORDS § 83.19 Government contractors. When GAO provides by a contract for the operation by or on behalf of GAO of a system of personnel...

4 CFR 83.19 - Government contractors.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 4 Accounts 1 2013-01-01 2013-01-01 false Government contractors. 83.19 Section 83.19 Accounts GOVERNMENT ACCOUNTABILITY OFFICE RECORDS PRIVACY PROCEDURES FOR PERSONNEL RECORDS § 83.19 Government contractors. When GAO provides by a contract for the operation by or on behalf of GAO of a system of personnel...

4 CFR 83.19 - Government contractors.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 4 Accounts 1 2012-01-01 2012-01-01 false Government contractors. 83.19 Section 83.19 Accounts GOVERNMENT ACCOUNTABILITY OFFICE RECORDS PRIVACY PROCEDURES FOR PERSONNEL RECORDS § 83.19 Government contractors. When GAO provides by a contract for the operation by or on behalf of GAO of a system of personnel...

4 CFR 83.19 - Government contractors.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 4 Accounts 1 2014-01-01 2013-01-01 true Government contractors. 83.19 Section 83.19 Accounts GOVERNMENT ACCOUNTABILITY OFFICE RECORDS PRIVACY PROCEDURES FOR PERSONNEL RECORDS § 83.19 Government contractors. When GAO provides by a contract for the operation by or on behalf of GAO of a system of personnel...

The Contractor's Role in Competitive Bid Construction.

ERIC Educational Resources Information Center

Toy, G. Arlan

1986-01-01

In a competitive bid situation, the general contractor's first priority is controlling construction costs. The actions the general contractor take focus on adequate control, effective communication, efficient use of resources, and prevention of delays. (MLF)

76 FR 60838 - Debarment, Suspension, and Ineligibility of Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... GOVERNMENT ACCOUNTABILITY OFFICE Debarment, Suspension, and Ineligibility of Contractors AGENCY... of government contractors. As a legislative branch agency, GAO is not subject to the requirements of... (hereinafter, contractors) who are responsible. However, GAO's Procurement Order has not explicitly referenced...

78 FR 12106 - Debarment, Suspension, and Ineligibility of Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

... OFFICE OF PERSONNEL MANAGEMENT Debarment, Suspension, and Ineligibility of Contractors AGENCY: U.S... Acquisition Regulation (FAR) regarding the debarment, suspension, and ineligibility of government contractors... ensure that it contracts only with those entities and individuals (hereinafter, contractors) who are...

GENETIC FINGERPRINTING OF MYCOBACTERIUM AVIUM COMPLEX (MAC) ORGANISMS ISOLATED FROM HOSPITAL PATIENTS AND THE ENVIRONMENT

EPA Science Inventory

A particularly pathogenic group of mycobacteria belong to the Mycobacterium avium complex (MAC), which includes M. avium and M. intracellulare. MAC organisms cause disease in children, the elderly, and immuno-compromised individuals. A critical step in preventing MAC infections...

77 FR 7579 - Debarment, Suspension, and Ineligibility of Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-13

... GOVERNMENT ACCOUNTABILITY OFFICE Debarment, Suspension, and Ineligibility of Contractors AGENCY... government contractors. Comments on GAO's policy were due on or before November 14, 2011. GAO received two... debarment, suspension, and ineligibility of government contractors. Neither comment suggested any changes to...

MacIntyre, Managerialism and Universities

ERIC Educational Resources Information Center

Stolz, Steven A.

2017-01-01

MacIntyre's earlier work and concern with social science enquiry not only exposes its limits, but also provides an insight into how its knowledge claims have been put to ideological use. He maintains that the institutional embodiment of these ideological ideas is the bureaucratic manager who has had a negative role to play in social structures…

Private Security Contractors: The Other Force

DTIC Science & Technology

2011-03-22

improving PSC oversight. This paper will not address private contractors conducting Police force training , governmental use of PSCs outside of Iraq...theater entry requirements, conduct mandatory training , conduct weapons training and qualification and conduct security verification and criminal...an effective oversight program including contractor deployment tracking, limited contract oversight personnel, and untrained Contract Officer

41 CFR 109-45.300-50 - Sales by designated contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... contractors. 109-45.300-50 Section 109-45.300-50 Public Contracts and Property Management Federal Property... § 109-45.300-50 Sales by designated contractors. Sales of surplus contractor inventory will be conducted by designated contractors when heads of field organizations determine that it is in the best interest...

48 CFR 2110.7002 - Contractor investment of FEGLI Program funds.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Contractor investment of FEGLI Program funds. (a) The Contractor is required to invest and reinvest all FEGLI... Contractor is required to credit income earned from its investment of FEGLI Program funds to the FEGLI... appropriate manner. If the Contractor fails to invest funds on hand, properly allocate investment income, or...

33 CFR 165.768 - Security Zone; MacDill Air Force Base, Tampa Bay, FL.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; MacDill Air Force....768 Security Zone; MacDill Air Force Base, Tampa Bay, FL. (a) Location. The following area is a... title. All waters within Tampa Bay, Florida in the vicinity of MacDill Air Force Base, including...

Characterization of the Murine Myeloid Precursor Cell Line MuMac-E8

PubMed Central

Fricke, Stephan; Riemschneider, Sina; Kohlschmidt, Janine; Hilger, Nadja; Fueldner, Christiane; Knauer, Jens; Sack, Ulrich; Emmrich, Frank; Lehmann, Jörg

2014-01-01

Starting point for the present work was the assumption that the cell line MuMac-E8 represents a murine cell population with stem cell properties. Preliminary studies already pointed to the expression of stem-cell associated markers and a self-regenerative potential of the cells. The cell line MuMac-E8 should be examined for their differential stage within stem cell hierarchy. MuMac-E8 cells were derived from a chimeric mouse model of arthritis. It could be shown that MuMac-E8 cells express mRNA of some genes associated with pluripotent stem cells (Nanog, Nucleostemin), of genes for hematopoietic markers (EPCR, Sca-1, CD11b, CD45), for the mesenchymal marker CD105 and of genes for the neural markers Pax-6 and Ezrin. In methylcellulose and May-Grünwald-Giemsa staining, hematopoietic colonies were obtained but the hematopoietic system of lethally irradiated mice could not be rescued. Osteogenic differentiation was not detectable. Thus, it became evident that MuMac-E8 represents not a stem cell line. However, MuMac-E8 cells expressed several myeloid surface markers (i.e. CD11b, F4/80, CD14, CD64), showed phagocytosis and is capable of producing nitric oxide. Thus, this cell line seems to be arrested an advanced stage of myeloid differentiation. Adherence data measured by impedance-based real-time cell analysis together with cell morphology data suggested that MuMac-E8 represents a new macrophage precursor cell line exhibiting weak adherence. This cell line is suitable as an in-vitro model for testing of macrophage functions. Moreover, it might be also useful for differentiation or reprogramming studies. PMID:25546418

48 CFR 252.244-7001 - Contractor purchasing system administration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...

48 CFR 252.244-7001 - Contractor purchasing system administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...

48 CFR 252.244-7001 - Contractor purchasing system administration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...

Millisecond timing on PCs and Macs.

PubMed

MacInnes, W J; Taylor, T L

2001-05-01

A real-time, object-oriented solution for displaying stimuli on Windows 95/98, MacOS and Linux platforms is presented. The program, written in C++, utilizes a special-purpose window class (GLWindow), OpenGL, and 32-bit graphics acceleration; it avoids display timing uncertainty by substituting the new window class for the default window code for each system. We report the outcome of tests for real-time capability across PC and Mac platforms running a variety of operating systems. The test program, which can be used as a shell for programming real-time experiments and testing specific processors, is available at http://www.cs.dal.ca/~macinnwj. We propose to provide researchers with a sense of the usefulness of our program, highlight the ability of many multitasking environments to achieve real time, as well as caution users about systems that may not achieve real time, even under optimal conditions.

MAP, MAC, and vortex-rings configurations in the Weinberg-Salam model

NASA Astrophysics Data System (ADS)

Teh, Rosy; Ng, Ban-Loong; Wong, Khai-Ming

2015-11-01

We report on the presence of new axially symmetric monopoles, antimonopoles and vortex-rings solutions of the SU(2)×U(1) Weinberg-Salam model of electromagnetic and weak interactions. When the ϕ-winding number n = 1, and 2, the configurations are monopole-antimonopole pair (MAP) and monopole-antimonopole chain (MAC) with poles of alternating sign magnetic charge arranged along the z-axis. Vortex-rings start to appear from the MAP and MAC configurations when the winding number n = 3. The MAP configurations possess zero net magnetic charge whereas the MAC configurations possess net magnetic charge of 4 πn / e. In the MAP configurations, the monopole-antimonopole pair is bounded by the Z0 field flux string and there is an electromagnetic current loop encircling it. The monopole and antimonopole possess magnetic charges ± 4πn/e sin2θW respectively. In the MAC configurations there is no string connecting the monopole and the adjacent antimonopole and they possess magnetic charges ± 4 πn/e respectively. The MAC configurations possess infinite total energy and zero magnetic dipole moment whereas the MAP configurations which are actually sphalerons possess finite total energy and magnetic dipole moment. The configurations were investigated for varying values of Higgs self-coupling constant 0 ≤ λ ≤ 40 at Weinberg angle θW = π/4.

48 CFR 47.305-15 - Loading responsibilities of contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Loading responsibilities of contractors. 47.305-15 Section 47.305-15 Federal Acquisition Regulations System FEDERAL... responsibilities of contractors. (a)(1) Contractors are responsible for loading, blocking, and bracing carload...

Ground-based plasma contractor characterization

NASA Technical Reports Server (NTRS)

Patterson, Michael J.; Aadland, Randall S.

1987-01-01

Presented are recent NASA Lewis Research Center (LeRC) plasma contractor experimental results, as well as a description of the plasma contractor test facility. The operation of a 24 cm diameter plasma source with hollow cathode was investigated in the lighted-mode regime of electron current collection from 0.1 to 7.0 A. These results are compared to those obtained with a 12 cm plasma source. Full two-dimensional plasma potential profiles were constructed from emissive probe traces of the contractor plume. The experimentally measured dimensions of the plume sheaths were then compared to those theoretically predicted using a model of a spherical double sheath. Results are consistent for currents up to approximately 1.0 A. For currents above 1.0 A, substantial deviations from theory occur. These deviations are due to sheath asphericity, and possibly volume ionization in the double-sheath region.

48 CFR 9.307 - Government administration procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Government administration... ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.307 Government..., to the Government laboratory or other activity responsible for approval at the address specified in...

48 CFR 9.307 - Government administration procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Government administration... ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.307 Government..., to the Government laboratory or other activity responsible for approval at the address specified in...

Annexin V-MACS in infertile couples as method for separation of sperm without DNA fragmentation.

PubMed

Troya, Jhon; Zorrilla, Ingrid

2015-05-01

To determine the effect of using MACS technology on clinical pregnancy, as a method for separation of damaged sperm in infertile patients. 136 infertile men having normal semen parameters in accordance with WHO 2010 criterion, undergoing ICSI cycle were enrolled during the course of the study. The patients were prospectively randomized and enrolled after oocyte retrieval and were assigned to the ICSI group, PICSI group or MACS group. Embryo development and clinical pregnancy were assessed. In 17 randomized MACS patients, sperm DNA fragmentation was tested in the presumptive apoptotic and no apoptotic spermatozoa fractions. Similar results were obtained between groups for the following parameters: fertilization rates of 78.97% (95% confidence interval [CI]:74.37-83.57), 70.15 %(95% CI:63.98-76.33) and 80.28%(95% CI:73.74-86.81) for ICSI, PICSI and MACS group, respectively; Number of Day-3 embryos was 5.04 (95% CI:4.09-5.98), 5.17(95% CI:4.24-6.10) and 5.59(95% CI:4.31-6.87) for ICSI, PICSI and MACS group, respectively; number of freezing embryos in blastocyst stage was 0.78 (95% CI:0.25- 1.31), 0.70(95% CI:0.27-1.14) and 1 (95% CI:0.37-1.6) for ICSI, PICSI and MACS group, respectively. However, clinical pregnancy rates of 58.1% for MACS group versus 40.4% and 27.3% for PICSI and ICSI group, respectively, were showed statistical difference (P=0.019). DNA fragmentation index for the two sperm MACS fraction showed statistical differences (P=0.000), MACS reduced the D.F.I of the sperm sample. The use of MACS technology improves the clinical pregnancy on infertile couples and can be applied as a method for sperm separation, discriminating sperm with high DNA fragmentation.

Oligomeric Bax Is a Component of the Putative Cytochrome c Release Channel MAC, Mitochondrial Apoptosis-induced Channel

PubMed Central

Dejean, Laurent M.; Martinez-Caballero, Sonia; Guo, Liang; Hughes, Cynthia; Teijido, Oscar; Ducret, Thomas; Ichas, François; Korsmeyer, Stanley J.; Antonsson, Bruno; Jonas, Elizabeth A.; Kinnally, Kathleen W.

2005-01-01

Bcl-2 family proteins regulate apoptosis, in part, by controlling formation of the mitochondrial apoptosis-induced channel (MAC), which is a putative cytochrome c release channel induced early in the intrinsic apoptotic pathway. This channel activity was never observed in Bcl-2–overexpressing cells. Furthermore, MAC appears when Bax translocates to mitochondria and cytochrome c is released in cells dying by intrinsic apoptosis. Bax is a component of MAC of staurosporine-treated HeLa cells because MAC activity is immunodepleted by Bax antibodies. MAC is preferentially associated with oligomeric, not monomeric, Bax. The single channel behavior of recombinant oligomeric Bax and MAC is similar. Both channel activities are modified by cytochrome c, consistent with entrance of this protein into the pore. The mean conductance of patches of mitochondria isolated after green fluorescent protein-Bax translocation is significantly higher than those from untreated cells, consistent with onset of MAC activity. In contrast, the mean conductance of patches of mitochondria indicates MAC activity is present in apoptotic cells deficient in Bax but absent in apoptotic cells deficient in both Bax and Bak. These findings indicate Bax is a component of MAC in staurosporine-treated HeLa cells and suggest Bax and Bak are functionally redundant as components of MAC. PMID:15772159

77 FR 6676 - Office of Inspector General; Contractor Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-09

... POSTAL SERVICE 39 CFR Part 230 Office of Inspector General; Contractor Requirements AGENCY: Postal... for contractors employed by the Office of Inspector General. The rule also emphasizes consistency in contractor selection, and clarifies the OIG's exclusive authority to set qualifications and standards for its...

41 CFR 109-40.000-50 - Applicability to contractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... contractors. 109-40.000-50 Section 109-40.000-50 Public Contracts and Property Management Federal Property...-50 Applicability to contractors. DOE-PMR 109-40, Transportation and Traffic Management, should be applied to cost-type contractors' transportation and traffic management activities. Departure by cost-type...

An extended smart utilization medium access control (ESU-MAC) protocol for ad hoc wireless systems

NASA Astrophysics Data System (ADS)

Vashishtha, Jyoti; Sinha, Aakash

2006-05-01

The demand for spontaneous setup of a wireless communication system has increased in recent years for areas like battlefield, disaster relief operations etc., where a pre-deployment of network infrastructure is difficult or unavailable. A mobile ad-hoc network (MANET) is a promising solution, but poses a lot of challenges for all the design layers, specifically medium access control (MAC) layer. Recent existing works have used the concepts of multi-channel and power control in designing MAC layer protocols. SU-MAC developed by the same authors, efficiently uses the 'available' data and control bandwidth to send control information and results in increased throughput via decreasing contention on the control channel. However, SU-MAC protocol was limited for static ad-hoc network and also faced the busy-receiver node problem. We present the Extended SU-MAC (ESU-MAC) protocol which works mobile nodes. Also, we significantly improve the scheme of control information exchange in ESU-MAC to overcome the busy-receiver node problem and thus, further avoid the blockage of control channel for longer periods of time. A power control scheme is used as before to reduce interference and to effectively re-use the available bandwidth. Simulation results show that ESU-MAC protocol is promising for mobile, ad-hoc network in terms of reduced contention at the control channel and improved throughput because of channel re-use. Results show a considerable increase in throughput compared to SU-MAC which could be attributed to increased accessibility of control channel and improved utilization of data channels due to superior control information exchange scheme.

48 CFR 923.102 - Applicability to contractors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contractors. 923.102 Section 923.102 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Sustainable Acquisition 923.102 Applicability to contractors. Many of the...

48 CFR 923.102 - Applicability to contractors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contractors. 923.102 Section 923.102 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Sustainable Acquisition 923.102 Applicability to contractors. Many of the...

48 CFR 923.102 - Applicability to contractors.

Code of Federal Regulations, 2013 CFR

2013-10-01

... contractors. 923.102 Section 923.102 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Sustainable Acquisition 923.102 Applicability to contractors. Many of the...

48 CFR 923.102 - Applicability to contractors.

Code of Federal Regulations, 2012 CFR

2012-10-01

... contractors. 923.102 Section 923.102 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Sustainable Acquisition 923.102 Applicability to contractors. Many of the...

A Hybrid Path-Oriented Code Assignment CDMA-Based MAC Protocol for Underwater Acoustic Sensor Networks

PubMed Central

Chen, Huifang; Fan, Guangyu; Xie, Lei; Cui, Jun-Hong

2013-01-01

Due to the characteristics of underwater acoustic channel, media access control (MAC) protocols designed for underwater acoustic sensor networks (UWASNs) are quite different from those for terrestrial wireless sensor networks. Moreover, in a sink-oriented network with event information generation in a sensor field and message forwarding to the sink hop-by-hop, the sensors near the sink have to transmit more packets than those far from the sink, and then a funneling effect occurs, which leads to packet congestion, collisions and losses, especially in UWASNs with long propagation delays. An improved CDMA-based MAC protocol, named path-oriented code assignment (POCA) CDMA MAC (POCA-CDMA-MAC), is proposed for UWASNs in this paper. In the proposed MAC protocol, both the round-robin method and CDMA technology are adopted to make the sink receive packets from multiple paths simultaneously. Since the number of paths for information gathering is much less than that of nodes, the length of the spreading code used in the POCA-CDMA-MAC protocol is shorter greatly than that used in the CDMA-based protocols with transmitter-oriented code assignment (TOCA) or receiver-oriented code assignment (ROCA). Simulation results show that the proposed POCA-CDMA-MAC protocol achieves a higher network throughput and a lower end-to-end delay compared to other CDMA-based MAC protocols. PMID:24193100

A hybrid path-oriented code assignment CDMA-based MAC protocol for underwater acoustic sensor networks.

PubMed

Chen, Huifang; Fan, Guangyu; Xie, Lei; Cui, Jun-Hong

2013-11-04

Due to the characteristics of underwater acoustic channel, media access control (MAC) protocols designed for underwater acoustic sensor networks (UWASNs) are quite different from those for terrestrial wireless sensor networks. Moreover, in a sink-oriented network with event information generation in a sensor field and message forwarding to the sink hop-by-hop, the sensors near the sink have to transmit more packets than those far from the sink, and then a funneling effect occurs, which leads to packet congestion, collisions and losses, especially in UWASNs with long propagation delays. An improved CDMA-based MAC protocol, named path-oriented code assignment (POCA) CDMA MAC (POCA-CDMA-MAC), is proposed for UWASNs in this paper. In the proposed MAC protocol, both the round-robin method and CDMA technology are adopted to make the sink receive packets from multiple paths simultaneously. Since the number of paths for information gathering is much less than that of nodes, the length of the spreading code used in the POCA-CDMA-MAC protocol is shorter greatly than that used in the CDMA-based protocols with transmitter-oriented code assignment (TOCA) or receiver-oriented code assignment (ROCA). Simulation results show that the proposed POCA-CDMA-MAC protocol achieves a higher network throughput and a lower end-to-end delay compared to other CDMA-based MAC protocols.

MAC/GMC 4.0 User's Manual: Example Problem Manual. Volume 3

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Arnold, Steven M.

2002-01-01

This document is the third volume in the three volume set of User's Manuals for the Micromechanics Analysis Code with Generalized Method of Cells Version 4.0 (MAC/GMC 4.0). Volume 1 is the Theory Manual, Volume 2 is the Keywords Manual, and this document is the Example Problems Manual. MAC/GMC 4.0 is a composite material and laminate analysis software program developed at the NASA Glenn Research Center. It is based on the generalized method of cells (GMC) micromechanics theory, which provides access to the local stress and strain fields in the composite material. This access grants GMC the ability to accommodate arbitrary local models for inelastic material behavior and various types of damage and failure analysis. MAC/GMC 4.0 has been built around GMC to provide the theory with a user-friendly framework, along with a library of local inelastic, damage, and failure models. Further, application of simulated thermo-mechanical loading, generation of output results, and selection of architectures to represent the composite material, have been automated in MAC/GMC 4.0. Finally, classical lamination theory has been implemented within MAC/GMC 4.0 wherein GMC is used to model the composite material response of each ply. Consequently, the full range of GMC composite material capabilities is available for analysis of arbitrary laminate configurations as well. This volume provides in-depth descriptions of 43 example problems, which were specially designed to highlight many of the most important capabilities of the code. The actual input files associated with each example problem are distributed with the MAC/GMC 4.0 software; thus providing the user with a convenient starting point for their own specialized problems of interest.

77 FR 12754 - Contractor Legal Management Requirements; Acquisition Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... DEPARTMENT OF ENERGY 10 CFR Part 719 48 Parts 931, 952 and 970 RIN 1990-AA37 Contractor Legal... rulemaking (NOPR) to revise existing regulations covering contractor legal management requirements and make... relating to the DOE notice of proposed rulemaking to revise existing regulations covering contractor legal...

48 CFR 2452.237-75 - Clearance of contractor personnel.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Clearance of contractor... Clauses 2452.237-75 Clearance of contractor personnel. As prescribed in 2437.110(e), insert the following clause in solicitations and contracts. Clearance of Contractor Personnel (OCT 1999) (a) General. This...

48 CFR 1252.237-70 - Qualifications of contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor employees. 1252.237-70 Section 1252.237-70 Federal Acquisition Regulations System DEPARTMENT OF....237-70 Qualifications of contractor employees. As prescribed in (TAR) 48 CFR 1237.110(a), insert the following clause: Qualifications of Contractor Employees (APR 2005) a. Definitions. As used in this clause...

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

PubMed Central

Greene, Nicholas P.; Kaplan, Elise; Crow, Allister; Koronakis, Vassilis

2018-01-01

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that is distinct from other structurally characterized ABC transporters and uses a unique molecular mechanism termed mechanotransmission. Unlike other bacterial ABC transporters, MacB does not transport substrates across the inner membrane in which it is based, but instead couples cytoplasmic ATP hydrolysis with transmembrane conformational changes that are used to perform work in the extra-cytoplasmic space. In the MacAB-TolC tripartite pump, mechanotransmission drives efflux of antibiotics and export of a protein toxin from the periplasmic space via the TolC exit duct. Homologous tripartite systems from pathogenic bacteria similarly export protein-like signaling molecules, virulence factors and siderophores. In addition, many MacB-like ABC transporters do not form tripartite pumps, but instead operate in diverse cellular processes including antibiotic sensing, cell division and lipoprotein trafficking. PMID:29892271

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective.

PubMed

Greene, Nicholas P; Kaplan, Elise; Crow, Allister; Koronakis, Vassilis

2018-01-01

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that is distinct from other structurally characterized ABC transporters and uses a unique molecular mechanism termed mechanotransmission. Unlike other bacterial ABC transporters, MacB does not transport substrates across the inner membrane in which it is based, but instead couples cytoplasmic ATP hydrolysis with transmembrane conformational changes that are used to perform work in the extra-cytoplasmic space. In the MacAB-TolC tripartite pump, mechanotransmission drives efflux of antibiotics and export of a protein toxin from the periplasmic space via the TolC exit duct. Homologous tripartite systems from pathogenic bacteria similarly export protein-like signaling molecules, virulence factors and siderophores. In addition, many MacB-like ABC transporters do not form tripartite pumps, but instead operate in diverse cellular processes including antibiotic sensing, cell division and lipoprotein trafficking.

MacWilliams Identity for M-Spotty Weight Enumerator

NASA Astrophysics Data System (ADS)

Suzuki, Kazuyoshi; Fujiwara, Eiji

M-spotty byte error control codes are very effective for correcting/detecting errors in semiconductor memory systems that employ recent high-density RAM chips with wide I/O data (e.g., 8, 16, or 32bits). In this case, the width of the I/O data is one byte. A spotty byte error is defined as random t-bit errors within a byte of length b bits, where 1 le t ≤ b. Then, an error is called an m-spotty byte error if at least one spotty byte error is present in a byte. M-spotty byte error control codes are characterized by the m-spotty distance, which includes the Hamming distance as a special case for t =1 or t = b. The MacWilliams identity provides the relationship between the weight distribution of a code and that of its dual code. The present paper presents the MacWilliams identity for the m-spotty weight enumerator of m-spotty byte error control codes. In addition, the present paper clarifies that the indicated identity includes the MacWilliams identity for the Hamming weight enumerator as a special case.

The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function.

PubMed

Papadaki, Amalia; Politou, Anastasia S; Smirlis, Despina; Kotini, Maria P; Kourou, Konstadina; Papamarcaki, Thomais; Boleti, Haralabia

2015-05-01

Acid ecto-phosphatase activity has been implicated in Leishmania donovani promastigote virulence. In the present study, we report data contributing to the molecular/structural and functional characterization of the L. donovani LdMAcP (L. donovani membrane acid phosphatase), member of the histidine acid phosphatase (HAcP) family. LdMAcP is membrane-anchored and shares high sequence identity with the major secreted L. donovani acid phosphatases (LdSAcPs). Sequence comparison of the LdMAcP orthologues in Leishmania sp. revealed strain polymorphism and species specificity for the L. donovani complex, responsible for visceral leishmaniasis (Khala azar), proposing thus a potential value of LdMAcP as an epidemiological or diagnostic tool. The extracellular orientation of the LdMAcP catalytic domain was confirmed in L. donovani promastigotes, wild-type (wt) and transgenic overexpressing a recombinant LdMAcP-mRFP1 (monomeric RFP1) chimera, as well as in transiently transfected mammalian cells expressing rLdMAcP-His. For the first time it is demonstrated in the present study that LdMAcP confers tartrate resistant acid ecto-phosphatase activity in live L. donovani promastigotes. The latter confirmed the long sought molecular identity of at least one enzyme contributing to this activity. Interestingly, the L. donovani rLdMAcP-mRFP1 promastigotes generated in this study, showed significantly higher infectivity and virulence indexes than control parasites in the infection of J774 mouse macrophages highlighting thereby a role for LdMAcP in the parasite's virulence.

An energy-efficient MAC protocol using dynamic queue management for delay-tolerant mobile sensor networks.

PubMed

Li, Jie; Li, Qiyue; Qu, Yugui; Zhao, Baohua

2011-01-01

Conventional MAC protocols for wireless sensor network perform poorly when faced with a delay-tolerant mobile network environment. Characterized by a highly dynamic and sparse topology, poor network connectivity as well as data delay-tolerance, delay-tolerant mobile sensor networks exacerbate the severe power constraints and memory limitations of nodes. This paper proposes an energy-efficient MAC protocol using dynamic queue management (EQ-MAC) for power saving and data queue management. Via data transfers initiated by the target sink and the use of a dynamic queue management strategy based on priority, EQ-MAC effectively avoids untargeted transfers, increases the chance of successful data transmission, and makes useful data reach the target terminal in a timely manner. Experimental results show that EQ-MAC has high energy efficiency in comparison with a conventional MAC protocol. It also achieves a 46% decrease in packet drop probability, 79% increase in system throughput, and 25% decrease in mean packet delay.

An Energy-Efficient MAC Protocol Using Dynamic Queue Management for Delay-Tolerant Mobile Sensor Networks

PubMed Central

Li, Jie; Li, Qiyue; Qu, Yugui; Zhao, Baohua

2011-01-01

Conventional MAC protocols for wireless sensor network perform poorly when faced with a delay-tolerant mobile network environment. Characterized by a highly dynamic and sparse topology, poor network connectivity as well as data delay-tolerance, delay-tolerant mobile sensor networks exacerbate the severe power constraints and memory limitations of nodes. This paper proposes an energy-efficient MAC protocol using dynamic queue management (EQ-MAC) for power saving and data queue management. Via data transfers initiated by the target sink and the use of a dynamic queue management strategy based on priority, EQ-MAC effectively avoids untargeted transfers, increases the chance of successful data transmission, and makes useful data reach the target terminal in a timely manner. Experimental results show that EQ-MAC has high energy efficiency in comparison with a conventional MAC protocol. It also achieves a 46% decrease in packet drop probability, 79% increase in system throughput, and 25% decrease in mean packet delay. PMID:22319385

75 FR 3977 - Addressing Tax Delinquency by Government Contractors

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-25

... Contractors #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 75, No. 15 / Monday... of January 20, 2010 Addressing Tax Delinquency by Government Contractors Memorandum for the Heads of... contractors and has an important obligation to protect American taxpayer money and the integrity of the...

76 FR 81408 - Contractor Legal Management Requirements; Acquisition Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

... DEPARTMENT OF ENERGY 10 CFR Part 719 48 CFR Parts 931, 952 and 970 RIN 1990-AA37 Contractor Legal... Energy (DOE or Department) is proposing to revise existing regulations covering contractor legal... costs by certain contractors whose contracts exceed $100,000,000 as well as legal counsel retained...

78 FR 25795 - Contractor Legal Management Requirements; Acquisition Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-03

... DEPARTMENT OF ENERGY 10 CFR Part 719 48 CFR Parts 931, 952, and 970 RIN 1990-AA37 Contractor Legal.... ACTION: Final rule. SUMMARY: The Department of Energy revises existing regulations covering contractor... costs by certain contractors whose contracts exceed $100,000,000 as well as legal counsel retained...

48 CFR 52.236-6 - Superintendence by the Contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Contractor. 52.236-6 Section 52.236-6 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....236-6 Superintendence by the Contractor. As prescribed in 36.506, insert the following clause: Superintendence by the Contractor (APR 1984) At all times during performance of this contract and until the work...

48 CFR 752.7013 - Contractor-mission relationships.

Code of Federal Regulations, 2011 CFR

2011-10-01

....7013 Contractor-mission relationships. For use in all USAID contracts involving performance overseas... contract, and for advising USAID regarding the performance of the work under the contract and its effect on... of academic freedom. Notwithstanding these academic freedoms, the Contractor's employees, while in...

41 CFR 60-1.2 - Administrative responsibility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal Opportunity...

41 CFR 60-1.2 - Administrative responsibility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal Opportunity...

Public Relations as "Practice": Applying the Theory of Alasdair MacIntyre.

ERIC Educational Resources Information Center

Leeper, Roy V.; Leeper, Kathie A.

2001-01-01

Considers how public relation's search for a unifying theory may be fulfilled through application of Alasdair MacIntyre's concept of a "practice," a very specific and value-laden concept. Explores what it would mean to be a public relations practice in MacIntyre's concept of the term and argues that such an approach to public relations…

Synthesizing Existing CSMA and TDMA Based MAC Protocols for VANETs

PubMed Central

Huang, Jiawei; Li, Qi; Zhong, Shaohua; Liu, Lianhai; Zhong, Ping; Wang, Jianxin; Ye, Jin

2017-01-01

Many Carrier Sense Multiple Access (CSMA) and Time Division Multiple Access (TDMA) based medium access control (MAC) protocols for vehicular ad hoc networks (VANETs) have been proposed recently. Contrary to the common perception that they are competitors, we argue that the underlying strategies used in these MAC protocols are complementary. Based on this insight, we design CTMAC, a MAC protocol that synthesizes existing strategies; namely, random accessing channel (used in CSMA-style protocols) and arbitral reserving channel (used in TDMA-based protocols). CTMAC swiftly changes its strategy according to the vehicle density, and its performance is better than the state-of-the-art protocols. We evaluate CTMAC using at-scale simulations. Our results show that CTMAC reduces the channel completion time and increases the network goodput by 45% for a wide range of application workloads and network settings. PMID:28208590

Modeling MAC layer for powerline communications networks

NASA Astrophysics Data System (ADS)

Hrasnica, Halid; Haidine, Abdelfatteh

2001-02-01

The usage of electrical power distribution networks for voice and data transmission, called Powerline Communications, becomes nowadays more and more attractive, particularly in the telecommunication access area. The most important reasons for that are the deregulation of the telecommunication market and a fact that the access networks are still property of former monopolistic companies. In this work, first we analyze a PLC network and system structure as well as a disturbance scenario in powerline networks. After that, we define a logical structure of the powerline MAC layer and propose the reservation MAC protocols for the usage in the PLC network which provides collision free data transmission. This makes possible better network utilization and realization of QoS guarantees which can make PLC networks competitive to other access technologies.

76 FR 31416 - Federal Acquisition Regulation; Oversight of Contractor Ethics Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

...-AL92 Federal Acquisition Regulation; Oversight of Contractor Ethics Programs AGENCY: Department of... that contractors have implemented the mandatory contractor business ethics program requirements. DATES... to Improve DoD's Oversight of Contractor Ethics Programs. The ethics program requirement flows from...

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Technical Data 227.7108 Contractor data repositories. (a) Contractor data repositories may be established... procedures for protecting technical data delivered to or stored at the repository from unauthorized release... disclosure of technical data from the repository to third parties consistent with the Government's rights in...

7 CFR 1924.276 - Action against contractor.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.276 Action... construction defects which are the responsibility of the contractor, debarment proceedings will be initiated... the borrower's claim against the contractor or other party will be obtained if it appears to the...

7 CFR 1924.276 - Action against contractor.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.276 Action... construction defects which are the responsibility of the contractor, debarment proceedings will be initiated... the borrower's claim against the contractor or other party will be obtained if it appears to the...

7 CFR 1924.276 - Action against contractor.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.276 Action... construction defects which are the responsibility of the contractor, debarment proceedings will be initiated... the borrower's claim against the contractor or other party will be obtained if it appears to the...

7 CFR 1924.276 - Action against contractor.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.276 Action... construction defects which are the responsibility of the contractor, debarment proceedings will be initiated... the borrower's claim against the contractor or other party will be obtained if it appears to the...

7 CFR 1924.276 - Action against contractor.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.276 Action... construction defects which are the responsibility of the contractor, debarment proceedings will be initiated... the borrower's claim against the contractor or other party will be obtained if it appears to the...

48 CFR 1437.7001 - Contractor qualification requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractor qualification requirements. 1437.7001 Section 1437.7001 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Contractor qualification requirements. (a) Prior to award of a contract for real property appraisal services...

Deriving health utilities from the MacNew Heart Disease Quality of Life Questionnaire.

PubMed

Chen, Gang; McKie, John; Khan, Munir A; Richardson, Jeff R

2015-10-01

Quality of life is included in the economic evaluation of health services by measuring the preference for health states, i.e. health state utilities. However, most intervention studies include a disease-specific, not a utility, instrument. Consequently, there has been increasing use of statistical mapping algorithms which permit utilities to be estimated from a disease-specific instrument. The present paper provides such algorithms between the MacNew Heart Disease Quality of Life Questionnaire (MacNew) instrument and six multi-attribute utility (MAU) instruments, the Euroqol (EQ-5D), the Short Form 6D (SF-6D), the Health Utilities Index (HUI) 3, the Quality of Wellbeing (QWB), the 15D (15 Dimension) and the Assessment of Quality of Life (AQoL-8D). Heart disease patients and members of the healthy public were recruited from six countries. Non-parametric rank tests were used to compare subgroup utilities and MacNew scores. Mapping algorithms were estimated using three separate statistical techniques. Mapping algorithms achieved a high degree of precision. Based on the mean absolute error and the intra class correlation the preferred mapping is MacNew into SF-6D or 15D. Using the R squared statistic the preferred mapping is MacNew into AQoL-8D. The algorithms reported in this paper enable MacNew data to be mapped into utilities predicted from any of six instruments. This permits studies which have included the MacNew to be used in cost utility analyses which, in turn, allows the comparison of services with interventions across the health system. © The European Society of Cardiology 2014.

On Proper Selection of Multihop Relays for Future Enhancement of AeroMACS Networks

NASA Technical Reports Server (NTRS)

Kamali, Behnam; Kerczewski, Robert J.; Apaza, Rafael D.

2015-01-01

As the Aeronautical Mobile Airport Communications System (AeroMACS) has evolved from a technology concept to a deployed communications network over major US airports, it is now time to contemplate whether the existing capacity of AeroMACS is sufficient to meet the demands set forth by all fixed and mobile applications over the airport surface given the AeroMACS constraints regarding bandwidth and transmit power. The underlying idea in this article is to present IEEE 802.16j-based WiMAX as a technology that can address future capacity enhancements and therefore is most feasible for AeroMACS applications. The principal argument in favor IEEE 802.16j technology is the flexible and cost effective extension of radio coverage that is afforded by relay fortified networks, with virtually no increase in the power requirements and virtually no rise in interference levels to co-allocated applications. The IEEE 802.16j-based multihop relay systems are briefly described. The focus is on key features of this technology, frame structure, and its architecture. Next, AeroMACS is described as a WiMAX-based wireless network. The two major relay modes supported by IEEE 802.16j amendment, i.e., transparent and non-transparent are described. The benefits of employing multihop relays are listed. Some key challenges related to incorporating relays into AeroMACS networks are discussed. The selection of relay type in a broadband wireless network affects a number of network parameters such as latency, signal overhead, PHY (Scalable Physical Layer) and MAC (Media Access Layer) layer protocols, consequently it can alter key network quantities of throughput and QoS (Quality of Service).

Isolation and characterisation of human gingival margin-derived STRO-1/MACS+ and MACS− cell populations

PubMed Central

El-Sayed, Karim M Fawzy; Paris, Sebastian; Graetz, Christian; Kassem, Neemat; Mekhemar, Mohamed; Ungefroren, Hendrick; Fändrich, Fred; Dörfer, Christof

2015-01-01

Recently, gingival margin-derived stem/progenitor cells isolated via STRO-1/magnetic activated cell sorting (MACS) showed remarkable periodontal regenerative potential in vivo. As a second-stage investigation, the present study's aim was to perform in vitro characterisation and comparison of the stem/progenitor cell characteristics of sorted STRO-1-positive (MACS+) and STRO-1-negative (MACS−) cell populations from the human free gingival margin. Cells were isolated from the free gingiva using a minimally invasive technique and were magnetically sorted using anti-STRO-1 antibodies. Subsequently, the MACS+ and MACS− cell fractions were characterized by flow cytometry for expression of CD14, CD34, CD45, CD73, CD90, CD105, CD146/MUC18 and STRO-1. Colony-forming unit (CFU) and multilineage differentiation potential were assayed for both cell fractions. Mineralisation marker expression was examined using real-time polymerase chain reaction (PCR). MACS+ and MACS− cell fractions showed plastic adherence. MACS+ cells, in contrast to MACS− cells, showed all of the predefined mesenchymal stem/progenitor cell characteristics and a significantly higher number of CFUs (P<0.01). More than 95% of MACS+ cells expressed CD105, CD90 and CD73; lacked the haematopoietic markers CD45, CD34 and CD14, and expressed STRO-1 and CD146/MUC18. MACS− cells showed a different surface marker expression profile, with almost no expression of CD14 or STRO-1, and more than 95% of these cells expressed CD73, CD90 and CD146/MUC18, as well as the haematopoietic markers CD34 and CD45 and CD105. MACS+ cells could be differentiated along osteoblastic, adipocytic and chondroblastic lineages. In contrast, MACS− cells demonstrated slight osteogenic potential. Unstimulated MACS+ cells showed significantly higher expression of collagen I (P<0.05) and collagen III (P<0.01), whereas MACS− cells demonstrated higher expression of osteonectin (P<0.05; Mann–Whitney). The present study is the first to

77 FR 5020 - General Services Administration Acquisition Regulation; Information Collection; GSA Form 527...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... GENERAL SERVICES ADMINISTRATION [OMB Control No. 3090-0007; Docket 2011-0001; Sequence 12] General Services Administration Acquisition Regulation; Information Collection; GSA Form 527, Contractor's Qualifications and Financial Information AGENCY: Office of the Chief Finance Officer, GSA. ACTION: Notice of...

High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib.

PubMed

Chavakis, Triantafyllos; Santoso, Sentot; Clemetson, Kenneth J; Sachs, Ulrich J H; Isordia-Salas, Irma; Pixley, Robin A; Nawroth, Peter P; Colman, Robert W; Preissner, Klaus T

2003-11-14

Leukocyte-platelet interaction is important in mediating leukocyte adhesion to a thrombus and leukocyte recruitment to a site of vascular injury. This interaction is mediated at least in part by the beta2-integrin Mac-1 (CD11b/CD18) and its counter-receptor on platelets, glycoprotein Ibalpha (GPIbalpha). High molecular weight kininogen (HK) was previously shown to interact with both GPIbalpha and Mac-1 through its domains 3 and 5, respectively. In this study we investigated the ability of HK to interfere with the leukocyte-platelet interaction. In a purified system, HK binding to GPIbalpha was inhibited by HK domain 3 and the monoclonal antibody (mAb) SZ2, directed against the epitope 269-282 of GPIbalpha, whereas mAb AP1, directed to the region 201-268 of GPIbalpha had no effect. In contrast, mAb AP1 inhibited the Mac-1-GPIbalpha interaction. Binding of GPIbalpha to Mac-1 was enhanced 2-fold by HK. This effect of HK was abrogated in the presence of HK domains 3 or 5 or peptides from the 475-497 region of the carboxyl terminus of domain 5 as well as in the presence of mAb SZ2 but not mAb AP1. Whereas no difference in the affinity of the Mac-1-GPIbalpha interaction was observed in the absence or presence of HK, maximal binding of GPIbalpha to Mac-1 doubled in the presence of HK. Moreover, HK/HKa increased the Mac-1-dependent adhesion of myelomonocytic U937 cells and K562 cells transfected with Mac-1 to immobilized GPIbalpha or to GPIbalpha-transfected Chinese hamster ovary cells. Finally, Mac-1-dependent adhesion of neutrophils to surface-adherent platelets was enhanced by HK. Thus, HK can bridge leukocytes with platelets by interacting via its domain 3 with GPIbalpha and via its domain 5 with Mac-1 thereby augmenting the Mac-1-GPIbalpha interaction. These distinct molecular interactions of HK with leukocytes and platelets contribute to the regulation of the adhesive behavior of vascular cells and provide novel molecular targets for reducing atherothrombotic

23 CFR Appendix C to Subpart A of... - Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391)

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) C Appendix C to Subpart A of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS EXTERNAL PROGRAMS Equal Employment Opportunity on Federal and Federal-Aid...

23 CFR Appendix C to Subpart A of... - Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391)

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) C Appendix C to Subpart A of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS EXTERNAL PROGRAMS Equal Employment Opportunity on Federal and Federal-Aid...

23 CFR Appendix C to Subpart A of... - Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391)

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) C Appendix C to Subpart A of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS EXTERNAL PROGRAMS Equal Employment Opportunity on Federal and Federal-Aid...

Battlefield Contractors: Operational Risk and System Support Contractors

DTIC Science & Technology

2010-10-27

incentive for the use of contractors is the proven cost savings when compared to similarly trained active duty military forces. The Office of...no military or government civilian is trained to do. The reality is that “modern military operations now depend heavily on high-tech weapons systems...squadrons that rely exclusively on contracted line maintenance, with no military personnel trained to support the aircraft. Defense supplemental funds

48 CFR 1646.301 - Contractor inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor inspection requirements. 1646.301 Section 1646.301 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT... Clauses 1646.301 Contractor inspection requirements. The clause set forth at 1652.246-70 shall be inserted...

Testing MacArthur's minimisation principle: do communities minimise energy wastage during succession?

PubMed

Ghedini, Giulia; Loreau, Michel; White, Craig R; Marshall, Dustin J

2018-05-20

Robert MacArthur developed a theory of community assembly based on competition. By incorporating energy flow, MacArthur's theory allows for predictions of community function. A key prediction is that communities minimise energy wastage over time, but this minimisation is a trade-off between two conflicting processes: exploiting food resources, and maintaining low metabolism and mortality. Despite its simplicity and elegance, MacArthur's principle has not been tested empirically despite having long fascinated theoreticians. We used a combination of field chronosequence experiments and laboratory assays to estimate how the energy wastage of a community changes during succession. We found that older successional stages wasted more energy in maintenance, but there was no clear pattern in how communities of different age exploited food resources. We identify several reasons for why MacArthur's original theory may need modification and new avenues to further explore community efficiency, an understudied component of ecosystem functioning. © 2018 John Wiley & Sons Ltd/CNRS.

Industrial WSN Based on IR-UWB and a Low-Latency MAC Protocol

NASA Astrophysics Data System (ADS)

Reinhold, Rafael; Underberg, Lisa; Wulf, Armin; Kays, Ruediger

2016-07-01

Wireless sensor networks for industrial communication require high reliability and low latency. As current wireless sensor networks do not entirely meet these requirements, novel system approaches need to be developed. Since ultra wideband communication systems seem to be a promising approach, this paper evaluates the performance of the IEEE 802.15.4 impulse-radio ultra-wideband physical layer and the IEEE 802.15.4 Low Latency Deterministic Network (LLDN) MAC for industrial applications. Novel approaches and system adaptions are proposed to meet the application requirements. In this regard, a synchronization approach based on circular average magnitude difference functions (CAMDF) and on a clean template (CT) is presented for the correlation receiver. An adapted MAC protocol titled aggregated low latency (ALL) MAC is proposed to significantly reduce the resulting latency. Based on the system proposals, a hardware prototype has been developed, which proves the feasibility of the system and visualizes the real-time performance of the MAC protocol.

48 CFR 645.608 - Screening of contractor inventory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... inventory. 645.608 Section 645.608 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 645.608 Screening of contractor inventory. ...

A Cross-Layer Duty Cycle MAC Protocol Supporting a Pipeline Feature for Wireless Sensor Networks

PubMed Central

Tong, Fei; Xie, Rong; Shu, Lei; Kim, Young-Chon

2011-01-01

Although the conventional duty cycle MAC protocols for Wireless Sensor Networks (WSNs) such as RMAC perform well in terms of saving energy and reducing end-to-end delivery latency, they were designed independently and require an extra routing protocol in the network layer to provide path information for the MAC layer. In this paper, we propose a new cross-layer duty cycle MAC protocol with data forwarding supporting a pipeline feature (P-MAC) for WSNs. P-MAC first divides the whole network into many grades around the sink. Each node identifies its grade according to its logical hop distance to the sink and simultaneously establishes a sleep/wakeup schedule using the grade information. Those nodes in the same grade keep the same schedule, which is staggered with the schedule of the nodes in the adjacent grade. Then a variation of the RTS/CTS handshake mechanism is used to forward data continuously in a pipeline fashion from the higher grade to the lower grade nodes and finally to the sink. No extra routing overhead is needed, thus increasing the network scalability while maintaining the superiority of duty-cycling. The simulation results in OPNET show that P-MAC has better performance than S-MAC and RMAC in terms of packet delivery latency and energy efficiency. PMID:22163895

Pleiotrophin, a multifunctional cytokine and growth factor, induces leukocyte responses through the integrin Mac-1.

PubMed

Shen, Di; Podolnikova, Nataly P; Yakubenko, Valentin P; Ardell, Christopher L; Balabiyev, Arnat; Ugarova, Tatiana P; Wang, Xu

2017-11-17

Pleiotrophin (PTN) is a multifunctional, cationic, glycosaminoglycan-binding cytokine and growth factor involved in numerous physiological and pathological processes, including tissue repair and inflammation-related diseases. PTN has been shown to promote leukocyte responses by inducing their migration and expression of inflammatory cytokines. However, the mechanisms through which PTN mediates these responses remain unclear. Here, we identified the integrin Mac-1 (αMβ2, CD11b/CD18) as the receptor mediating macrophage adhesion and migration to PTN. We also found that expression of Mac-1 on the surface of human embryonic kidney (HEK) 293 cells induced their adhesion and migration to PTN. Accordingly, PTN promoted Mac-1-dependent cell spreading and initiated intracellular signaling manifested in phosphorylation of Erk1/2. While binding to PTN, Mac-1 on Mac-1-expressing HEK293 cells appears to cooperate with cell-surface proteoglycans because both anti-Mac-1 function-blocking mAb and heparin were required to block adhesion. Moreover, biolayer interferometry and NMR indicated a direct interaction between the α M I domain, the major ligand-binding region of Mac-1, and PTN. Using peptide libraries, we found that in PTN the α M I domain bound sequences enriched in basic and hydrophobic residues, indicating that PTN conforms to the general principle of ligand-recognition specificity of the α M I domain toward cationic proteins/peptides. Finally, using recombinant PTN-derived fragments, we show that PTN contains two distinct Mac-1-binding sites in each of its constitutive domains. Collectively, these results identify PTN as a ligand for the integrin Mac-1 on the surface of leukocytes and suggest that this interaction may play a role in inflammatory responses. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Integration of Occupational Safety to Contractors` or Subcontractors` Performance Evaluation in Construction Projects

NASA Astrophysics Data System (ADS)

Kozlovská, Mária; Struková, Zuzana

2013-06-01

Several factors should be considered by the owner and general contractor in the process of contractors` and subcontractors` selection and evaluation. The paper reviews the recent models addressed to guide general contractors in subcontractors' selection process and in evaluation of different contractors during the execution of the project. Moreover the paper suggests the impact of different contractors' performance to the overall level of occupational health and safety culture at the sites. It deals with the factors influencing the safety performance of contractors during construction and analyses the methods for assessing the safety performance of construction contractors. The results of contractors' safety performance evaluation could be a useful tool in motivating contractors to achieve better safety outcomes or could have effect on owners` or general contractors' decision making about contractors suitability for future contracting works.

Application of Multihop Relay for Performance Enhancement of AeroMACS Networks

NASA Technical Reports Server (NTRS)

Kamali, Behnam; Wilson, Jeffrey D.; Kerczewski, Robert J.

2012-01-01

A new transmission technology, based on IEEE 802.16-2009 (WiMAX), is currently being developed for airport surface communications. A C-band spectrum allocation at 5091-5150 MHz has been created by ITU to carry this application. The proposed technology, known as AeroMACS, will be used to support fixed and mobile ground to ground applications and services. This article proposes and demonstrates that IEEE 802.16j-amendment-based WiMAX is most feasible for AeroMACS applications. This amendment introduces multihop relay as an optional deployment that may be used to provide additional coverage and/or enhance the capacity of the network. Particular airport surface radio coverage situations for which IEEE 802.16-2009-WiMAX provides resolutions that are inefficient, costly, or excessively power consuming are discussed. In all these cases, it is argued that 16j technology offers a much better alternative. A major concern about deployment of AeroMACS is interference to co-allocated applications such as the Mobile Satellite Service (MSS) feeder link. Our initial simulation results suggest that no additional interference to MSS feeder link is caused by deployment of IEEE 802.16j-based AeroMACS.

Application of Multihop Relay for Performance Enhancement of AeroMACS Networks

NASA Technical Reports Server (NTRS)

Kamali, Behnam; Wilson, Jeffrey D.; Kerczewski, Robert J.

2012-01-01

A new transmission technology, based on IEEE 802.16-2009 (WiMAX), is currently being developed for airport surface communications. A C-band spectrum allocation at 5091 to 5150 MHz has been created by International Telecommunications Union (ITU) to carry this application. The proposed technology, known as AeroMACS, will be used to support fixed and mobile ground to ground applications and services. This article proposes and demonstrates that IEEE 802.16j-amendment-based WiMAX is most feasible for AeroMACS applications. This amendment introduces multihop relay as an optional deployment that may be used to provide additional coverage and/or enhance the capacity of the network. Particular airport surface radio coverage situations for which IEEE 802.16-2009-WiMAX provides resolutions that are inefficient, costly, or excessively power consuming are discussed. In all these cases, it is argued that 16j technology offers a much better alternative. A major concern about deployment of AeroMACS is interference to co-allocated applications such as the Mobile Satellite Service (MSS) feeder link. Our initial simulation results suggest that no additional interference to MSS feeder link is caused by deployment of IEEE 802.16j-based AeroMACS.

MacMillan Pier Transportation Center Feasibility Study.

DOT National Transportation Integrated Search

2006-06-01

The MacMillan Pier Transportation Center Feasibility Study examines two potential sites (landside and waterside) for a transportation center that provides a range of tourist and traveler information. It would serve as a gateway for Provincetown and t...

7 CFR 3015.183 - Access to contractor records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... contractor records. The Attachment 0 requires recipients to include in specified kinds of contracts a... applies to the provision: (a) The provision must require the contractor to place the same provision in any...

48 CFR 1004.470 - Investigative Requirements for Contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Investigative Requirements for Contractors. 1004.470 Section 1004.470 Federal Acquisition Regulations System DEPARTMENT OF THE... Investigative Requirements for Contractors. ...

Highway Funding: The Federal Highway Administration's Funding Apportionment Model

DOT National Transportation Integrated Search

1997-06-01

The Federal Highway Administration (FHWA) has developed and is operating, through the use of a contractor, a new apportionment model to estimate the expected distribution of federal-aid funds under various legislative proposals. Because of the import...

A Power-Optimized Cooperative MAC Protocol for Lifetime Extension in Wireless Sensor Networks.

PubMed

Liu, Kai; Wu, Shan; Huang, Bo; Liu, Feng; Xu, Zhen

2016-10-01

In wireless sensor networks, in order to satisfy the requirement of long working time of energy-limited nodes, we need to design an energy-efficient and lifetime-extended medium access control (MAC) protocol. In this paper, a node cooperation mechanism that one or multiple nodes with higher channel gain and sufficient residual energy help a sender relay its data packets to its recipient is employed to achieve this objective. We first propose a transmission power optimization algorithm to prolong network lifetime by optimizing the transmission powers of the sender and its cooperative nodes to maximize their minimum residual energy after their data packet transmissions. Based on it, we propose a corresponding power-optimized cooperative MAC protocol. A cooperative node contention mechanism is designed to ensure that the sender can effectively select a group of cooperative nodes with the lowest energy consumption and the best channel quality for cooperative transmissions, thus further improving the energy efficiency. Simulation results show that compared to typical MAC protocol with direct transmissions and energy-efficient cooperative MAC protocol, the proposed cooperative MAC protocol can efficiently improve the energy efficiency and extend the network lifetime.

A Power-Optimized Cooperative MAC Protocol for Lifetime Extension in Wireless Sensor Networks

PubMed Central

Liu, Kai; Wu, Shan; Huang, Bo; Liu, Feng; Xu, Zhen

2016-01-01

In wireless sensor networks, in order to satisfy the requirement of long working time of energy-limited nodes, we need to design an energy-efficient and lifetime-extended medium access control (MAC) protocol. In this paper, a node cooperation mechanism that one or multiple nodes with higher channel gain and sufficient residual energy help a sender relay its data packets to its recipient is employed to achieve this objective. We first propose a transmission power optimization algorithm to prolong network lifetime by optimizing the transmission powers of the sender and its cooperative nodes to maximize their minimum residual energy after their data packet transmissions. Based on it, we propose a corresponding power-optimized cooperative MAC protocol. A cooperative node contention mechanism is designed to ensure that the sender can effectively select a group of cooperative nodes with the lowest energy consumption and the best channel quality for cooperative transmissions, thus further improving the energy efficiency. Simulation results show that compared to typical MAC protocol with direct transmissions and energy-efficient cooperative MAC protocol, the proposed cooperative MAC protocol can efficiently improve the energy efficiency and extend the network lifetime. PMID:27706079

Crystallization and preliminary X-ray crystallographic analysis of MacA from Actinobacillus actinomycetemcomitans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piao, Shunfu; Xu, Yongbin; Ha, Nam-Chul, E-mail: hnc@pusan.ac.kr

2008-05-01

A periplasmic membrane-fusion protein MacA from Actinobacillus actinomycetemcomitans, an essential component of the multidrug efflux pump in Gram-negative bacteria, was crystallized. Periplasmic membrane-fusion proteins (MFPs) are an essential component of the multidrug efflux pump in Gram-negative bacteria. They play a crucial role in bridging the outer membrane porin TolC and two distinct types of inner membrane transporters. The MFP MacA bridges the inner membrane ABC-type multidrug transporter MacB and the outer membrane porin TolC. MacA from the pathogenic bacterium Actinobacillus actinomycetemcomitans was expressed in Escherichia coli B834 (DE3) and the recombinant protein was purified using Ni–NTA affinity, Q anion-exchange andmore » gel-filtration chromatography. The purified MacA protein was crystallized using the vapour-diffusion method. A MAD diffraction data set was collected to a resolution of 3.0 Å at 100 K. The crystal belongs to space group P622, with unit-cell parameters a = b = 109.2, c = 255.4 Å, α = β = 90, γ = 120°, and contains one molecule in the asymmetric unit.« less

Self-Admitted Pretensions of Mac Users on a Predominantly PC University Campus

ERIC Educational Resources Information Center

Firmin, Michael W.; Wood, Whitney L. Muhlenkamp; Firmin, Ruth L.; Wood, Jordan C.

2010-01-01

The present qualitative research study addressed the overall research question of college students' pretention dynamics in the context of a university setting. Thirty-five Mac users were interviewed on a university campus that exclusively supports PC machines. Mac users shared four self-admitted pretensions related to using Macintosh computers.…

21 CFR 20.90 - Disclosure to contractors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... employees; (4) Limitations on reproduction, transmission, and disclosure of the data and information; (5) A... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Disclosure to contractors. 20.90 Section 20.90...

21 CFR 20.90 - Disclosure to contractors.

Code of Federal Regulations, 2014 CFR

2014-04-01

... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... employees; (4) Limitations on reproduction, transmission, and disclosure of the data and information; (5) A... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Disclosure to contractors. 20.90 Section 20.90...

BIG MAC: A bolometer array for mid-infrared astronomy, Center Director's Discretionary Fund

NASA Technical Reports Server (NTRS)

Telesco, C. M.; Decher, R.; Baugher, C.

1985-01-01

The infrared array referred to as Big Mac (for Marshall Array Camera), was designed for ground based astronomical observations in the wavelength range 5 to 35 microns. It contains 20 discrete gallium-doped germanium bolometer detectors at a temperature of 1.4K. Each bolometer is irradiated by a square field mirror constituting a single pixel of the array. The mirrors are arranged contiguously in four columns and five rows, thus defining the array configuration. Big Mac utilized cold reimaging optics and an up looking dewar. The total Big Mac system also contains a telescope interface tube for mounting the dewar and a computer for data acquisition and processing. Initial astronomical observations at a major infrared observatory indicate that Big Mac performance is excellent, having achieved the design specifications and making this instrument an outstanding tool for astrophysics.

Contractor Performed Quality Control on KyTC Projects.

DOT National Transportation Integrated Search

2002-08-01

This report addresses issues related to transferring the responsibility for quality control from the Kentucky Transportation Cabinet (KyTC) to construction contractors. : Several key topics related to Contractor Performed Quality Control (CPQC) are p...

Impact of MAC Delay on AUV Localization: Underwater Localization Based on Hyperbolic Frequency Modulation Signal.

PubMed

Kim, Sungryul; Yoo, Younghwan

2018-01-26

Medium Access Control (MAC) delay which occurs between the anchor node's transmissions is one of the error sources in underwater localization. In particular, in AUV localization, the MAC delay significantly degrades the ranging accuracy. The Cramer-Rao Low Bound (CRLB) definition theoretically proves that the MAC delay significantly degrades the localization performance. This paper proposes underwater localization combined with multiple access technology to decouple the localization performance from the MAC delay. Towards this goal, we adopt hyperbolic frequency modulation (HFM) signal that provides multiplexing based on its good property, high-temporal correlation. Owing to the multiplexing ability of the HFM signal, the anchor nodes can transmit packets without MAC delay, i.e., simultaneous transmission is possible. In addition, the simulation results show that the simultaneous transmission is not an optional communication scheme, but essential for the localization of mobile object in underwater.

48 CFR 1403.570 - Restrictions on contractor advertising.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Restrictions on contractor advertising. 1403.570 Section 1403.570 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... 1403.570 Restrictions on contractor advertising. ...

48 CFR 1403.570 - Restrictions on contractor advertising.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Restrictions on contractor advertising. 1403.570 Section 1403.570 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... 1403.570 Restrictions on contractor advertising. ...

48 CFR 1403.570 - Restrictions on contractor advertising.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Restrictions on contractor advertising. 1403.570 Section 1403.570 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... 1403.570 Restrictions on contractor advertising. ...

48 CFR 1403.570 - Restrictions on contractor advertising.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Restrictions on contractor advertising. 1403.570 Section 1403.570 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... 1403.570 Restrictions on contractor advertising. ...

48 CFR 252.237-7023 - Continuation of Essential Contractor Services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... prescribed in 237.7603, use the following clause: Continuation of Mission Essential Functions (Date) (a) The... contractor services in support of mission-essential functions. The contractor-provided services that have been determined to be essential contractor services in support of mission-essential functions are...

76 FR 48776 - Federal Acquisition Regulation; Documenting Contractor Performance; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

... Regulation; Documenting Contractor Performance; Correction AGENCY: Department of Defense (DoD), General... published in the Federal Register of June 28, 2011, regarding the proposed rule for Documenting Contractor... published in the Federal Register of June 28, 2011, regarding the proposed rule for Documenting Contractor...

Performance analysis and improvement of WPAN MAC for home networks.

PubMed

Mehta, Saurabh; Kwak, Kyung Sup

2010-01-01

The wireless personal area network (WPAN) is an emerging wireless technology for future short range indoor and outdoor communication applications. The IEEE 802.15.3 medium access control (MAC) is proposed to coordinate the access to the wireless medium among the competing devices, especially for short range and high data rate applications in home networks. In this paper we use analytical modeling to study the performance analysis of WPAN (IEEE 802.15.3) MAC in terms of throughput, efficient bandwidth utilization, and delay with various ACK policies under error channel condition. This allows us to introduce a K-Dly-ACK-AGG policy, payload size adjustment mechanism, and Improved Backoff algorithm to improve the performance of the WPAN MAC. Performance evaluation results demonstrate the impact of our improvements on network capacity. Moreover, these results can be very useful to WPAN application designers and protocol architects to easily and correctly implement WPAN for home networking.

Performance Analysis and Improvement of WPAN MAC for Home Networks

PubMed Central

Mehta, Saurabh; Kwak, Kyung Sup

2010-01-01

The wireless personal area network (WPAN) is an emerging wireless technology for future short range indoor and outdoor communication applications. The IEEE 802.15.3 medium access control (MAC) is proposed to coordinate the access to the wireless medium among the competing devices, especially for short range and high data rate applications in home networks. In this paper we use analytical modeling to study the performance analysis of WPAN (IEEE 802.15.3) MAC in terms of throughput, efficient bandwidth utilization, and delay with various ACK policies under error channel condition. This allows us to introduce a K-Dly-ACK-AGG policy, payload size adjustment mechanism, and Improved Backoff algorithm to improve the performance of the WPAN MAC. Performance evaluation results demonstrate the impact of our improvements on network capacity. Moreover, these results can be very useful to WPAN application designers and protocol architects to easily and correctly implement WPAN for home networking. PMID:22319274

23 CFR Appendix C to Subpart A of... - Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391)

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Federal-Aid Highway Contractors Annual EEO Report (Form PR-1391) C Appendix C to Subpart A of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF... Construction Contracts (Including Supportive Services) Pt. 230, Subpt. A, App. C Appendix C to Subpart A of...

78 FR 63193 - Farm Credit Administration Board; Sunshine Act; Regular Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-23

... September 12, 2012 B. New Business Farmer Mac Liquidity Management--Final Rule Flood Insurance--Proposed... business. FOR FURTHER INFORMATION CONTACT: Dale L. Aultman, Secretary to the Farm Credit Administration..., McLean, Virginia 22102-5090. SUPPLEMENTARY INFORMATION: This meeting of the Board will be open to the...

Impact of MAC Delay on AUV Localization: Underwater Localization Based on Hyperbolic Frequency Modulation Signal

PubMed Central

2018-01-01

Medium Access Control (MAC) delay which occurs between the anchor node’s transmissions is one of the error sources in underwater localization. In particular, in AUV localization, the MAC delay significantly degrades the ranging accuracy. The Cramer-Rao Low Bound (CRLB) definition theoretically proves that the MAC delay significantly degrades the localization performance. This paper proposes underwater localization combined with multiple access technology to decouple the localization performance from the MAC delay. Towards this goal, we adopt hyperbolic frequency modulation (HFM) signal that provides multiplexing based on its good property, high-temporal correlation. Owing to the multiplexing ability of the HFM signal, the anchor nodes can transmit packets without MAC delay, i.e., simultaneous transmission is possible. In addition, the simulation results show that the simultaneous transmission is not an optional communication scheme, but essential for the localization of mobile object in underwater. PMID:29373518

Spermatozoa with numerical chromosomal abnormalities are more prone to be retained by Annexin V-MACS columns.

PubMed

Esbert, M; Godo, A; Soares, S R; Florensa, M; Amorós, D; Ballesteros, A; Vidal, F

2017-07-01

Colloidal super-paramagnetic microbeads conjugated with annexin V are effective for separating apoptotic spermatozoa by MACS as a result of the high affinity of annexin V for externalized PS molecules. The effectiveness of the procedure in reducing the percentage of sperm with fragmented DNA and abnormal morphology has also been reported. However, it is still unknown if it could decrease the percentage of aneuploid spermatozoa. The objective of our prospective study, performed on 16 males with abnormal FISH on spermatozoa, was to assess if MACS columns were useful tools to retain spermatozoa carrying chromosomal abnormalities in semen samples processed after density gradient centrifugation (DGC). The pellet obtained after DGC was subjected to MACS, and sperm FISH analyses were performed both in the eluded fraction and in the fraction retained in the column. The observed frequencies of disomy and nullisomy 13, 18, and 21, X and Y, as well as the diploidy rates in the MACS eluded fraction and the fraction retained in the MACS column were recorded. We observed that the frequencies of aneuploidies in the eluded fraction were lower than in the fraction retained in the MACS column (0.59% vs. 0.75%; p = 0.010). DGC determined a significant reduction in sperm concentration (z-ratio = 2.83; p = 0.005) and a significant increase in sperm progressive motility (z-ratio = -3.5; p < 0.001). MACS also led to a significant reduction in sperm concentration (z-ratio = 3.14; p = 0.002) and a significant increase in progressive motility (z-ratio = -2.59; p = 0.01) when compared with the post-DGC sample. Sperm concentration was similar in the two fractions generated by MACS (z-ratio = 0.63; p = 0.52), while progressive motility was significantly higher in the MACS eluded fraction (z-ratio = 2.42; p = 0.02). According to our results, MACS columns are able to selectively retain spermatozoa carrying chromosomal abnormalities. Furthermore, the performance of DGC

A Very Low Power MAC (VLPM) Protocol for Wireless Body Area Networks

PubMed Central

Ullah, Niamat; Khan, Pervez; Kwak, Kyung Sup

2011-01-01

Wireless Body Area Networks (WBANs) consist of a limited number of battery operated nodes that are used to monitor the vital signs of a patient over long periods of time without restricting the patient’s movements. They are an easy and fast way to diagnose the patient’s status and to consult the doctor. Device as well as network lifetime are among the most important factors in a WBAN. Prolonging the lifetime of the WBAN strongly depends on controlling the energy consumption of sensor nodes. To achieve energy efficiency, low duty cycle MAC protocols are used, but for medical applications, especially in the case of pacemakers where data have time-limited relevance, these protocols increase latency which is highly undesirable and leads to system instability. In this paper, we propose a low power MAC protocol (VLPM) based on existing wakeup radio approaches which reduce energy consumption as well as improving the response time of a node. We categorize the traffic into uplink and downlink traffic. The nodes are equipped with both a low power wake-up transmitter and receiver. The low power wake-up receiver monitors the activity on channel all the time with a very low power and keeps the MCU (Micro Controller Unit) along with main radio in sleep mode. When a node [BN or BNC (BAN Coordinator)] wants to communicate with another node, it uses the low-power radio to send a wakeup packet, which will prompt the receiver to power up its primary radio to listen for the message that follows shortly. The wake-up packet contains the desired node’s ID along with some other information to let the targeted node to wake-up and take part in communication and let all other nodes to go to sleep mode quickly. The VLPM protocol is proposed for applications having low traffic conditions. For high traffic rates, optimization is needed. Analytical results show that the proposed protocol outperforms both synchronized and unsynchronized MAC protocols like T-MAC, SCP-MAC, B-MAC and X-MAC in

THE EFFECT OF TEMPERATURE ON THE GROWTH OF MYCOBACTERIUM AVIUM COMPLEX (MAC) ORGANISMS

EPA Science Inventory

MAC organisms are able to grow, persist, and colonize in water distribution systems and may amplify in hospital hot water systems. This study examined the response of MAC organisms (M. avium, M. intracellulare, and MX) to a range of temperatures commonly associated with drinking...

Seeing Glass Contractors Clearly.

ERIC Educational Resources Information Center

Deliberato, Jerry

2003-01-01

Offers seven tips for finding and working with an effective glass contractor. For example, schools should consider the company's reputation and longevity of service, and whether it has in-house engineering capabilities. (EV)

48 CFR 252.204-7010 - Requirement for Contractor to Notify DoD if the Contractor's Activities are Subject to Reporting...

Code of Federal Regulations, 2010 CFR

2010-10-01

... of vulnerabilities to IAEA inspections or visits; (ii) Notify the Contractor of the time at which the... with DoD officials in the assessment of vulnerabilities to IAEA inspections or visits. (d) Following a...) Whether the Contractor's facility has any vulnerabilities where potentially declarable activities under...

STS-52 MS Veach and Payload Specialist MacLean during JSC bailout exercises

NASA Technical Reports Server (NTRS)

1992-01-01

STS-52 Columbia, Orbiter Vehicle (OV) 102, Mission Specialist (MS) Charles Lacy Veach (left) and Canadian Payload Specialist Steven G. MacLean listen to a briefing during emergency egress (bailout) training exercises in JSC's Weightless Environment Training Facility (WETF) Bldg 29. Veach and MacLean are fully outfitted in launch and entry suits (LESs), launch and entry helmets (LEHs), parachutes, and water survival equipment including a life jacket. The WETF's 25-ft deep pool will simulate the ocean as the crewmember's prepare for the event of a water landing. MacLean represents the Canadian Space Agency (CSA).

Matrix-assisted cocrystallization (MAC) simultaneous production and formulation of pharmaceutical cocrystals by hot-melt extrusion.

PubMed

Boksa, Kevin; Otte, Andrew; Pinal, Rodolfo

2014-09-01

A novel method for the simultaneous production and formulation of pharmaceutical cocrystals, matrix-assisted cocrystallization (MAC), is presented. Hot-melt extrusion (HME) is used to create cocrystals by coprocessing the drug and coformer in the presence of a matrix material. Carbamazepine (CBZ), nicotinamide (NCT), and Soluplus were used as a model drug, coformer, and matrix, respectively. The MAC product containing 80:20 (w/w) cocrystal:matrix was characterized by differential scanning calorimetry, Fourier transform infrared spectroscopy, and powder X-ray diffraction. A partial least squares (PLS) regression model was developed for quantifying the efficiency of cocrystal formation. The MAC product was estimated to be 78% (w/w) cocrystal (theoretical 80%), with approximately 0.3% mixture of free (unreacted) CBZ and NCT, and 21.6% Soluplus (theoretical 20%) with the PLS model. A physical mixture (PM) of a reference cocrystal (RCC), prepared by precipitation from solution, and Soluplus resulted in faster dissolution relative to the pure RCC. However, the MAC product with the exact same composition resulted in considerably faster dissolution and higher maximum concentration (∼five-fold) than those of the PM. The MAC product consists of high-quality cocrystals embedded in a matrix. The processing aspect of MAC plays a major role on the faster dissolution observed. The MAC approach offers a scalable process, suitable for the continuous manufacturing and formulation of pharmaceutical cocrystals. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

A Survey of MAC Protocols for Cognitive Radio Body Area Networks.

PubMed

Bhandari, Sabin; Moh, Sangman

2015-04-20

The advancement in electronics, wireless communications and integrated circuits has enabled the development of small low-power sensors and actuators that can be placed on, in or around the human body. A wireless body area network (WBAN) can be effectively used to deliver the sensory data to a central server, where it can be monitored, stored and analyzed. For more than a decade, cognitive radio (CR) technology has been widely adopted in wireless networks, as it utilizes the available spectra of licensed, as well as unlicensed bands. A cognitive radio body area network (CRBAN) is a CR-enabled WBAN. Unlike other wireless networks, CRBANs have specific requirements, such as being able to automatically sense their environments and to utilize unused, licensed spectra without interfering with licensed users, but existing protocols cannot fulfill them. In particular, the medium access control (MAC) layer plays a key role in cognitive radio functions, such as channel sensing, resource allocation, spectrum mobility and spectrum sharing. To address various application-specific requirements in CRBANs, several MAC protocols have been proposed in the literature. In this paper, we survey MAC protocols for CRBANs. We then compare the different MAC protocols with one another and discuss challenging open issues in the relevant research.

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation.

PubMed

van Spriel, A B; Leusen, J H; van Egmond, M; Dijkman, H B; Assmann, K J; Mayadas, T N; van de Winkel, J G

2001-04-15

Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor cooperation with Fc receptors (FcRs). The role of Mac-1 in FcR-mediated lysis of tumor cells was characterized by studying normal human PMNs, Mac-1-deficient mouse PMNs, and mouse PMNs transgenic for human FcR. All PMNs efficiently phagocytosed Ab-coated particles. However, antibody-dependent cellular cytotoxicity (ADCC) was abrogated in Mac-1(-/-) PMNs and in human PMNs blocked with anti-Mac-1 monoclonal Ab (mAb). Mac-1(-/-) PMNs were unable to spread on Ab-opsonized target cells and other Ab-coated surfaces. Confocal laser scanning and electron microscopy revealed a striking difference in immunologic synapse formation between Mac-1(-/-) and wild-type PMNs. Also, respiratory burst activity could be measured outside membrane-enclosed compartments by using Mac-1(-/-) PMNs bound to Ab-coated tumor cells, in contrast to wild-type PMNs. In summary, these data document an absolute requirement of Mac-1 for FcR-mediated PMN cytotoxicity toward tumor targets. Mac-1(-/-) PMNs exhibit defective spreading on Ab-coated targets, impaired formation of immunologic synapses, and absent tumor cytolysis.

29 CFR 500.60 - Farm labor contractors' recruitment, contractual and general obligations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Farm labor contractors' recruitment, contractual and... labor contractors' recruitment, contractual and general obligations. The Act imposes certain specific recruitment, contractual and general obligations on farm labor contractors and farm labor contractor employees...

Intrusion Detection for Defense at the MAC and Routing Layers of Wireless Networks

DTIC Science & Technology

2007-01-01

Space DoS Denial of Service DSR Dynamic Source Routing IDS Intrusion Detection System LAR Location-Aided Routing MAC Media Access Control MACA Multiple...different mobility parameters. 10 They simulate interaction between three MAC protocols ( MACA , 802.11 and CSMA) and three routing protocols (AODV, DSR

48 CFR 236.201 - Evaluation of contractor performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTS Special Aspects of Contracting for Construction 236.201 Evaluation of contractor performance. (a) Preparation of performance evaluation reports. Use DD Form 2626, Performance Evaluation (Construction... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Evaluation of contractor...

48 CFR 253.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... required service. (B) Production capability. An evaluation of the prospective contractor's ability to plan.... (C) Quality assurance capability. An assessment of the prospective contractor's capability to meet the quality assurance requirements of the proposed contract. It may involve an evaluation of the...

32 CFR 516.21 - Litigation against government contractors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Litigation against government contractors. 516... Litigation against government contractors. (a) General. A contract might require that the government... the underlying contract with the government requires reimbursement for adverse judgments or costs of...

MacArthur Competence Assessment Tool for Treatment in Alzheimer disease: cross-cultural adaptation.

PubMed

Santos, Raquel Luiza; Sousa, Maria Fernanda Barroso de; Simões, José Pedro; Bertrand, Elodie; Mograbi, Daniel C; Landeira-Fernandez, Jesus; Laks, Jerson; Dourado, Marcia Cristina Nascimento

2017-01-01

We adapted the MacArthur Competence Assessment Tool for Treatment (MacCAT-T) to Brazilian Portuguese, pilot testing it on mild and moderate patients with Alzheimer's disease (AD). The cross-cultural process required six steps. Sixty-six patients with AD were assessed for competence to consent to treatment, global cognition, working memory, awareness of disease, functionality, depressive symptoms and dementia severity. The items had semantic, idiomatic, conceptual and experiential equivalence. We found no difference between mild and moderate patients with AD on the MacCAT-T domains. The linear regressions showed that reasoning (p = 0.000) and functional status (p = 0.003) were related to understanding. Understanding (p = 0.000) was related to appreciation and reasoning. Awareness of disease (p = 0.001) was related to expressing a choice. The MacCAT-T adaptation was well-understood and the constructs of the original version were maintained. The results of the pilot study demonstrated an available Brazilian tool focused on decision-making capacity in AD.

TraPy-MAC: Traffic Priority Aware Medium Access Control Protocol for Wireless Body Area Network.

PubMed

Ullah, Fasee; Abdullah, Abdul Hanan; Kaiwartya, Omprakash; Cao, Yue

2017-06-01

Recently, Wireless Body Area Network (WBAN) has witnessed significant attentions in research and product development due to the growing number of sensor-based applications in healthcare domain. Design of efficient and effective Medium Access Control (MAC) protocol is one of the fundamental research themes in WBAN. Static on-demand slot allocation to patient data is the main approach adopted in the design of MAC protocol in literature, without considering the type of patient data specifically the level of severity on patient data. This leads to the degradation of the performance of MAC protocols considering effectiveness and traffic adjustability in realistic medical environments. In this context, this paper proposes a Traffic Priority-Aware MAC (TraPy-MAC) protocol for WBAN. It classifies patient data into emergency and non-emergency categories based on the severity of patient data. The threshold value aided classification considers a number of parameters including type of sensor, body placement location, and data transmission time for allocating dedicated slots patient data. Emergency data are not required to carry out contention and slots are allocated by giving the due importance to threshold value of vital sign data. The contention for slots is made efficient in case of non-emergency data considering threshold value in slot allocation. Moreover, the slot allocation to emergency and non-emergency data are performed parallel resulting in performance gain in channel assignment. Two algorithms namely, Detection of Severity on Vital Sign data (DSVS), and ETS Slots allocation based on the Severity on Vital Sign (ETS-SVS) are developed for calculating threshold value and resolving the conflicts of channel assignment, respectively. Simulations are performed in ns2 and results are compared with the state-of-the-art MAC techniques. Analysis of results attests the benefit of TraPy-MAC in comparison with the state-of-the-art MAC in channel assignment in realistic medical

10 CFR 1060.201 - Relatives, contractors, and assistance award recipients.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Relatives, contractors, and assistance award recipients... under § 1060.101(a)(1), a DOE contractor or a DOE assistance award recipient or the employee of a DOE contractor or a DOE assistance award recipient unless the travel expenses are incurred with respect to...

10 CFR 1060.201 - Relatives, contractors, and assistance award recipients.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Relatives, contractors, and assistance award recipients... under § 1060.101(a)(1), a DOE contractor or a DOE assistance award recipient or the employee of a DOE contractor or a DOE assistance award recipient unless the travel expenses are incurred with respect to...

10 CFR 1060.201 - Relatives, contractors, and assistance award recipients.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Relatives, contractors, and assistance award recipients... under § 1060.101(a)(1), a DOE contractor or a DOE assistance award recipient or the employee of a DOE contractor or a DOE assistance award recipient unless the travel expenses are incurred with respect to...

10 CFR 1060.201 - Relatives, contractors, and assistance award recipients.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Relatives, contractors, and assistance award recipients... under § 1060.101(a)(1), a DOE contractor or a DOE assistance award recipient or the employee of a DOE contractor or a DOE assistance award recipient unless the travel expenses are incurred with respect to...

10 CFR 1060.201 - Relatives, contractors, and assistance award recipients.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Relatives, contractors, and assistance award recipients... under § 1060.101(a)(1), a DOE contractor or a DOE assistance award recipient or the employee of a DOE contractor or a DOE assistance award recipient unless the travel expenses are incurred with respect to...

A Guide to Resolving Disputes Over Contractor Delay Entitlements.

DTIC Science & Technology

1993-12-01

E. Sanvido Associate Professor of Architectural Engineering Chin Y. Ku Professor f Civil Engineering Head of th Department of Accesion For Civil an...specifically states otherwise, the contractor is generally entitled to recover losses sustained by delays caused by the owner. 18 In the 1961 appeal, In Re...of time for causes beyond the contractor’s control foreclosed the contractor from recovering damage sustained by him because of the City’s failure to

48 CFR 253.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracts, or contracts which provide for progress payments based on costs or on a percentage or stage of...) Packaging. An assessment of the prospective contractor's ability to meet all contractual packaging...)). (E) Plant safety. An assessment of the prospective contractor's ability to meet the safety...

48 CFR 970.5244-1 - Contractor purchasing system.

Code of Federal Regulations, 2013 CFR

2013-10-01

... real property. Real property shall be acquired in accordance with 48 CFR subpart 917.74. (d) Advance notice of proposed subcontract awards. Advance notice shall be provided in accordance with 48 CFR 970.... (i) Contractor-affiliated sources. Equipment, materials, supplies, or services from a contractor...

48 CFR 970.5244-1 - Contractor purchasing system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... real property. Real property shall be acquired in accordance with 48 CFR subpart 917.74. (d) Advance notice of proposed subcontract awards. Advance notice shall be provided in accordance with 48 CFR 970.... (i) Contractor-affiliated sources. Equipment, materials, supplies, or services from a contractor...

48 CFR 253.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section III, Block 19, generally mean— (A) Technical capability. An assessment of the prospective contractor's key management personnel to determine if they have the basic technical knowledge, experience... completion. This includes— (1) An assessment of the prospective contractor's possession of, or the ability to...

48 CFR 36.201 - Evaluation of contractor performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Evaluation of contractor performance. 36.201 Section 36.201 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Contracting for Construction 36.201 Evaluation of contractor performance. See 42.1502(e) for the requirements...

48 CFR 49.405 - Completion by another contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Completion by another contractor. 49.405 Section 49.405 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... contractor. If the surety does not arrange for completion of the contract, the contracting officer normally...

Macular telangiectasia type 2 (MacTel) in a 34-year-old patient

PubMed Central

Nicolai, Heleen; Wirix, Mieke; Spielberg, Leigh; Leys, Anita

2014-01-01

We report macular telangiectasia type 2 (MacTel) in a 34-year-old man, the youngest patient so far published with MacTel type 2. The patient presented with metamorphopsia and impaired reading ability. Diagnosis was based on bilateral abnormal macular autofluorescence, perifoveal telangiectasia with fluorescein angiographic hyperfluorescence without cystoid oedema, a small foveal avascular zone, asymmetric configuration of the foveal pit, disruptions in the inner segment/outer segment layer and hyper-reflective haze and spots in the outer nuclear layer. Although MacTel usually manifests with a slowly progressive decrease in visual acuity in the fifth to seventh decades of life, younger patients may occasionally be diagnosed with the disease. Awareness of subtle signs of the condition is essential for early diagnosis. PMID:25249218

Walking on water: the biomechanics of Michael A. MacConaill (1902-1987).

PubMed

Prendergast, P J; Lee, T C

2006-01-01

Biomechanics is a subject that draws on knowledge from many disciplines. One of its great practitioners in the last century was the Irish anatomist M.A. MacConaill. In this paper, we review some of MacConaill's fundamental contributions to biomechanics, namely: the hydrodynamic theory of synovial joint lubrication, the kinematics of joint motion and conjunct rotations; and the theory of spurt and shunt muscles. The aim is to revisit these topics in the light of current research, and to draw some conclusions about the import of his research in the context of recent developments in the field. The paper concludes with a discussion of science in Ireland, the development of the field of biomechanics since MacConaill's time, and some other matters.

An energy-efficient rate adaptive media access protocol (RA-MAC) for long-lived sensor networks.

PubMed

Hu, Wen; Chen, Quanjun; Corke, Peter; O'Rourke, Damien

2010-01-01

We introduce an energy-efficient Rate Adaptive Media Access Control (RA-MAC) algorithm for long-lived Wireless Sensor Networks (WSNs). Previous research shows that the dynamic and lossy nature of wireless communications is one of the major challenges to reliable data delivery in WSNs. RA-MAC achieves high link reliability in such situations by dynamically trading off data rate for channel gain. The extra gain that can be achieved reduces the packet loss rate which contributes to reduced energy expenditure through a reduced numbers of retransmissions. We achieve this at the expense of raw bit rate which generally far exceeds the application's link requirement. To minimize communication energy consumption, RA-MAC selects the optimal data rate based on the estimated link quality at each data rate and an analytical model of the energy consumption. Our model shows how the selected data rate depends on different channel conditions in order to minimize energy consumption. We have implemented RA-MAC in TinyOS for an off-the-shelf sensor platform (the TinyNode) on top of a state-of-the-art WSN Media Access Control Protocol, SCP-MAC, and evaluated its performance by comparing our implementation with the original SCP-MAC using both simulation and experiment.

77 FR 43078 - Federal Acquisition Regulation; Information Collection; Central Contractor Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-23

...; Information Collection; Central Contractor Registration AGENCY: Department of Defense (DOD), General Services... requirement concerning the Central Contractor Registration database. Public comments are particularly invited... Information Collection 9000- 0159, Central Contractor Registration, by any of the following methods...

78 FR 12316 - Federal Acquisition Regulation; Information Collection; Central Contractor Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-22

...; Information Collection; Central Contractor Registration AGENCIES: Department of Defense (DOD), General... collection requirement concerning the Central Contractor Registration database. A notice was published in the... Information Collection 9000- 0159, Central Contractor Registration, by any of the following methods...

Independent contractors versus employees: the costs and benefits for your practice.

PubMed

Buzogany, William A; Mueller, Michael J

2010-01-01

Every business is interested in reducing costs. Payroll and employee benefit costs can be reduced through the use of independent contractors, because they are not employees to whom training, overtime wages, and benefits must be provided. Using the services of an independent contractor presents some disadvantages, however, as an independent contractor cannot be controlled and disciplined in the same fashion as an employee. There are a variety of tests applied under various statutes to determine whether an individual is an employee or an independent contractor, and it is important to carefully analyze all of the facts of a given situation in light of these tests before entering into an independent contractor relationship. If you engage an individual as an independent contractor, and that individual is found to actually be an employee, your business may be subject to significant financial penalties.

The Polish MacNew heart disease heath-related quality of life questionnaire: a validation study.

PubMed

Moryś, Joanna M; Höfer, Stefan; Rynkiewicz, Andrzej; Oldridge, Neil Bryan

2015-01-01

The MacNew health-related quality of life questionnaire was designed to assess feelings about how heart disease affects their daily physical, emotional and social functioning in patients with 1 of the 3 major coronary artery diagnoses, stable coronary artery disease (CAD) with angina, ST-elevation myocardial infarction (STEMI), and ischemic heart failure (HF). The aim of this study was to determine the reliability and validity of the Polish version of the MacNew in patients with CAD. Patients with CAD completed a self-report sociodemographic and clinical ques-tionnaire: the MacNew, the Short-Form 36 Health Survey, and HADS at baseline; 10% of the patients completed each questionnaire 2 weeks later. We studied patients with stable CAD with angina (n = 115), with STEMI (n = 112), and with ischemic HF (n = 105). Internal consistency reliability was demonstrated with Cronbach's a from 0.86 to 0.95 for the MacNew global scale and subscales. The original 3-factor structure was confirmed for the Polish version of the MacNew explaining 53.5% of the variance. Convergent validity of similar MacNew and SF-36 subscales was confirmed in the total group and in each diagnosis. Discriminant validity with the SF-36 health transition was fully confirmed in the total group and in patients with HF and partially confirmed in patients with stable CAD with angina or myocardial infarction. The Polish MacNew health-related quality of life questionnaire can be recommended in patients with stable CAD with angina, myocardial infarction and HF.

Contractor Logistics Support in the U.S. Air Force

DTIC Science & Technology

2009-01-01

limits), or it can engage in a mix of the two approaches.2 This monograph addresses CLS, which is defined as contractor sustainment of a weapon system...organic facilities; it can pay contractors to do the work (subject to some congressional limits); or it can apply a mix of the two approaches.2 Organic...levels are largely stable and represent a mix of services, including contractor operated facilities and instal- Figure 3.1 Air Force CSS for Weapon

10 CFR 824.16 - Direction to NNSA contractors.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Direction to NNSA contractors. 824.16 Section 824.16 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR THE ASSESSMENT OF CIVIL PENALTIES FOR CLASSIFIED... the following actions that direct NNSA contractors or subcontractors. (1) Subpoenas; (2) Orders to...

48 CFR 52.204-7 - Central Contractor Registration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... (CCR) database means the primary Government repository for Contractor information required for the...) for the same concern. Registered in the CCR database means that— (1) The Contractor has entered all... Federal Funding Accountability and Transparency Act of 2006 (see subpart 4.14), into the CCR database; and...

The vertex operator for a generalization of MacMahon’s formula

NASA Astrophysics Data System (ADS)

Cai, Liqiang; Wang, Lifang; Wu, Ke; Yang, Jie

2015-10-01

We provide a vertex operator realization for a two-parameter generalization of MacMahon’s formula introduced by M. Vuletić [Trans. Amer. Math. Soc. 361, 2789 (2009)]. Since the generalized MacMahon function is the kernel function of some Macdonald symmetric function, we consider the action of two vertex operators on a state corresponding to a Macdonald symmetric function. It becomes evident that the vertex operators appear to be the creation and annihilation operators, respectively on the state.

MacA is a second cytochrome c peroxidase of Geobacter sulfurreducens.

PubMed

Seidel, Julian; Hoffmann, Maren; Ellis, Katie E; Seidel, Antonia; Spatzal, Thomas; Gerhardt, Stefan; Elliott, Sean J; Einsle, Oliver

2012-04-03

The metal-reducing δ-proteobacterium Geobacter sulfurreducens produces a large number of c-type cytochromes, many of which have been implicated in the transfer of electrons to insoluble metal oxides. Among these, the dihemic MacA was assigned a central role. Here we have produced G. sulfurreducens MacA by recombinant expression in Escherichia coli and have solved its three-dimensional structure in three different oxidation states. Sequence comparisons group MacA into the family of diheme cytochrome c peroxidases, and the protein indeed showed hydrogen peroxide reductase activity with ABTS(-2) as an electron donor. The observed K(M) was 38.5 ± 3.7 μM H(2)O(2) and v(max) was 0.78 ± 0.03 μmol of H(2)O(2)·min(-1)·mg(-1), resulting in a turnover number k(cat) = 0.46 · s(-1). In contrast, no Fe(III) reductase activity was observed. MacA was found to display electrochemical properties similar to other bacterial diheme peroxidases, in addition to the ability to electrochemically mediate electron transfer to the soluble cytochrome PpcA. Differences in activity between CcpA and MacA can be rationalized with structural variations in one of the three loop regions, loop 2, that undergoes conformational changes during reductive activation of the enzyme. This loop is adjacent to the active site heme and forms an open loop structure rather than a more rigid helix as in CcpA. For the activation of the protein, the loop has to displace the distal ligand to the active site heme, H93, in loop 1. A H93G variant showed an unexpected formation of a helix in loop 2 and disorder in loop 1, while a M297H variant that altered the properties of the electron transfer heme abolished reductive activation.

MacA is a Second Cytochrome c Peroxidase of Geobacter sulfurreducens

PubMed Central

Seidel, Julian; Hoffmann, Maren; Ellis, Katie E.; Seidel, Antonia; Spatzal, Thomas; Gerhardt, Stefan; Elliott, Sean J.

2012-01-01

The metal-reducing δ-proteobacterium Geobacter sulfurreducens produces a large number of c-type cytochromes, many of which have been implicated in the transfer of electrons to insoluble metal oxides. Among these, the dihemic MacA was assigned a central role. Here we have produced G. sulfurreducens MacA by recombinant expression in Escherichia coli and have solved its three-dimensional structure in three different oxidation states. Sequence comparisons group MacA into the family of diheme cytochrome c peroxidases, and the protein indeed showed hydrogen peroxide reductase activity with ABTS2– as an electron donor. The observed KM was 38.5 ± 3.7 μM H2O2 and vmax was 0.78 ± 0.03 μmol H2O2·min–1·mg–1, resulting in a turnover number kcat = 0.46 · s–1. In contrast, no Fe(III) reductase activity was observed. MacA was found to display similar electrochemical properties to other bacterial diheme peroxidases, in additional to the ability to electrochemically mediate electron transfer to the soluble cytochrome PpcA. Differences in activity between CcpA and MacA can be rationalized with structural variations in one of the three loop regions, loop 2, that undergo conformational changes during reductive activation of the enzyme. This loop is adjacent to the active site heme and forms an open loop structure rather than a more rigid helix as in CcpA. For the activation of the protein the loop has to displace the distal ligand to the active site heme, H93, in loop 1. A H93G variant showed an unexpected formation of a helix in loop 2 and disorder in loop 1, while a M297H variant that altered the properties of the electron transfer heme abolished reductive activation. PMID:22417533

Optimal Contractor Selection in Construction Industry: The Fuzzy Way

NASA Astrophysics Data System (ADS)

Krishna Rao, M. V.; Kumar, V. S. S.; Rathish Kumar, P.

2018-02-01

A purely price-based approach to contractor selection has been identified as the root cause for many serious project delivery problems. Therefore, the capability of the contractor to execute the project should be evaluated using a multiple set of selection criteria including reputation, past performance, performance potential, financial soundness and other project specific criteria. An industry-wide questionnaire survey was conducted with the objective of identifying the important criteria for adoption in the selection process. In this work, a fuzzy set based model was developed for contractor prequalification/evaluation, by using effective criteria obtained from the percept of construction professionals, taking subjective judgments of decision makers also into consideration. A case study consisting of four alternatives (contractors in the present case) solicited from a public works department of Pondicherry in India, is used to illustrate the effectiveness of the proposed approach. The final selection of contractor is made based on the integrated score or Overall Evaluation Score of the decision alternative in prequalification as well as bid evaluation stages.

30 CFR 46.12 - Responsibility for independent contractor training.

Code of Federal Regulations, 2010 CFR

2010-07-01

... providing new miner training, newly hired experienced miner training, new task training, and annual... which the contractor is aware that may be created by the performance of the contractor's work at the...

10 CFR 727.6 - What are the obligations of a DOE contractor?

Code of Federal Regulations, 2012 CFR

2012-01-01

... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

10 CFR 727.6 - What are the obligations of a DOE contractor?

Code of Federal Regulations, 2013 CFR

2013-01-01

... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

10 CFR 727.6 - What are the obligations of a DOE contractor?

Code of Federal Regulations, 2014 CFR

2014-01-01

... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

10 CFR 727.6 - What are the obligations of a DOE contractor?

Code of Federal Regulations, 2010 CFR

2010-01-01

... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

10 CFR 727.6 - What are the obligations of a DOE contractor?

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

48 CFR 52.204-7 - Central Contractor Registration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (CCR) database means the primary Government repository for Contractor information required for the...) for the same concern. Registered in the CCR database means that— (1) The Contractor has entered all mandatory information, including the DUNS number or the DUNS+4 number, into the CCR database; and (2) The...

32 CFR 516.21 - Litigation against government contractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Litigation against government contractors. 516.21 Section 516.21 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL... lawsuit requests representation by DOJ, the Army presumes the contractor will obtain private counsel to...

Poincaré-MacMillan Equations of Motion for a Nonlinear Nonholonomic Dynamical System

NASA Astrophysics Data System (ADS)

Amjad, Hussain; Syed Tauseef, Mohyud-Din; Ahmet, Yildirim

2012-03-01

MacMillan's equations are extended to Poincaré's formalism, and MacMillan's equations for nonlinear nonholonomic systems are obtained in terms of Poincaré parameters. The equivalence of the results obtained here with other forms of equations of motion is demonstrated. An illustrative example of the theory is provided as well.

Telecommunications administration standard

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gustwiller, K.D.

1996-05-01

The administration of telecommunications is critical to proper maintenance and operation. The intent is to be able to properly support telecommunications for the distribution of all information within a building/campus. This standard will provide a uniform administration scheme that is independent of applications, and will establish guidelines for owners, installers, designers and contractors. This standard will accommodate existing building wiring, new building wiring and outside plant wiring. Existing buildings may not readily adapt to all applications of this standard, but the requirement for telecommunications administration is applicable to all buildings. Administration of the telecommunications infrastructure includes documentation (labels, records, drawings,more » reports, and work orders) of cables, termination hardware, patching and cross-connect facilities, telecommunications rooms, and other telecommunications spaces (conduits, grounding, and cable pathways are documented by Facilities Engineering). The investment in properly documenting telecommunications is a worthwhile effort. It is necessary to adhere to these standards to ensure quality and efficiency for the operation and maintenance of the telecommunications infrastructure for Sandia National Laboratories.« less

Current evidence for the use of C-MAC videolaryngoscope in adult airway management: a review of the literature

PubMed Central

Xue, Fu-Shan; Li, Hui-Xian; Liu, Ya-Yang; Yang, Gui-Zhen

2017-01-01

The C-MAC videolaryngoscope is the first Macintosh-typed videolaryngoscope. Since the advent of its original version video Macintosh system in 1999, this device has been modified several times. A unique feature of C-MAC device is its ability to provide the 2 options of direct and video laryngoscopy with the same device. The available evidence shows that in patients with normal airways, C-MAC videolaryngoscope compared with direct laryngoscopy can provide comparable or better laryngeal views and exerts less force on maxillary incisors, but does not offer conclusive benefits with regard to intubation time, intubation success, number of intubation attempts, the use of adjuncts, and hemodynamic responses to intubation. In patients with predicted or known difficult airways, C-MAC videolaryngoscope can achieve a better laryngeal view, a higher intubation success rate and a shorter intubation time than direct laryngoscopy. Furthermore, the option to perform direct and video laryngoscopy with the same device makes C-MAC videolaryngoscope exceptionally useful for emergency intubation. In addition, the C-MAC videolaryngoscope is a very good tool for tracheal intubation teaching. However, tracheal intubation with C-MAC videolaryngoscope may occasionally fail and introduction of C-MAC videolaryngoscope in clinical practice must be accompanied by formal training programs in normal and difficult airway managements. PMID:28740393

Macular telangiectasia type 2 (MacTel) in a 34-year-old patient.

PubMed

Nicolai, Heleen; Wirix, Mieke; Spielberg, Leigh; Leys, Anita

2014-09-23

We report macular telangiectasia type 2 (MacTel) in a 34-year-old man, the youngest patient so far published with MacTel type 2. The patient presented with metamorphopsia and impaired reading ability. Diagnosis was based on bilateral abnormal macular autofluorescence, perifoveal telangiectasia with fluorescein angiographic hyperfluorescence without cystoid oedema, a small foveal avascular zone, asymmetric configuration of the foveal pit, disruptions in the inner segment/outer segment layer and hyper-reflective haze and spots in the outer nuclear layer. Although MacTel usually manifests with a slowly progressive decrease in visual acuity in the fifth to seventh decades of life, younger patients may occasionally be diagnosed with the disease. Awareness of subtle signs of the condition is essential for early diagnosis. 2014 BMJ Publishing Group Ltd.

10 CFR 820.13 - Direction to NNSA contractors.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Direction to NNSA contractors. 820.13 Section 820.13 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.13 Direction to..., issues and serves the following actions that direct NNSA contractors: (1) Subpoenas; (2) Orders to compel...

10 CFR 851.45 - Direction to NNSA contractors.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Direction to NNSA contractors. 851.45 Section 851.45 Energy DEPARTMENT OF ENERGY WORKER SAFETY AND HEALTH PROGRAM Enforcement Process § 851.45 Direction to... than the Director, signs, issues and serves the following actions that direct NNSA contractors: (1...

3 CFR - Addressing Tax Delinquency by Government Contractors

Code of Federal Regulations, 2011 CFR

2011-01-01

... 3 The President 1 2011-01-01 2011-01-01 false Addressing Tax Delinquency by Government Contractors Presidential Documents Other Presidential Documents Memorandum of January 20, 2010 Addressing Tax Delinquency by Government Contractors Memorandum for the Heads of Executive Departments and Agencies The Federal Government pays more than half a...

Deconstructing the McGurk-MacDonald Illusion

ERIC Educational Resources Information Center

Soto-Faraco, Salvador; Alsius, Agnes

2009-01-01

Cross-modal illusions such as the McGurk-MacDonald effect have been used to illustrate the automatic, encapsulated nature of multisensory integration. This characterization is based in the widespread assumption that the illusory percept arising from intersensory conflict reflects only the end-product of the multisensory integration process, with…

Integrated, Kerberized Login on MacOS X

NASA Technical Reports Server (NTRS)

Hotz, Henry B.

2006-01-01

Context for this information. MacOS X login process and available hooks. Authorization Services configuration. Authorization Services plug-in s. Kerberos plug-in s. Other bugs and recommendations. Authorization Services Called by loginwindow, screen saver and fast user switching. It calls Directory Services, Login Hook, and Login Items (System Preferences).

40 CFR 35.4195 - Are there certain people my group cannot select to be our technical advisor, grant administrator...

Code of Federal Regulations, 2010 CFR

2010-07-01

... cannot select to be our technical advisor, grant administrator, or other contractor under the grant? 35... ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance Procuring A Technical Advisor Or Other Contractor with Tag Funds § 35.4195 Are there certain people my group cannot select to be our technical...

Performance Analysis of IEEE 802.15.3 MAC Protocol with Different ACK Polices

NASA Astrophysics Data System (ADS)

Mehta, S.; Kwak, K. S.

The wireless personal area network (WPAN) is an emerging wireless technology for future short range indoor and outdoor communication applications. The IEEE 802.15.3 medium access control (MAC) is proposed, specially, for short range high data rates applications, to coordinate the access to the wireless medium among the competing devices. This paper uses analytical model to study the performance analysis of WPAN (IEEE 802.15.3) MAC in terms of throughput, efficient bandwidth utilization, and delay with various acknowledgment schemes under different parameters. Also, some important observations are obtained, which can be very useful to the protocol architectures. Finally, we come up with some important research issues to further investigate the possible improvements in the WPAN MAC.

Skylab checkout operations. [from multiple docking adapter contractor viewpoint

NASA Technical Reports Server (NTRS)

Timmons, K. P.

1973-01-01

The Skylab Program at Kennedy Space Center presented many opportunities for interesting and profound test and checkout experience. It also offered a compilation of challenges and promises for the Center and for the contractors responsible for the various modules making up Skylab. It is very probable that the various contractors had common experiences during the module and combined systems tests, but this paper will discuss those experiences from the viewpoint of the Multiple Docking Adapter contractor. The experience will consider personnel, procedures, and hardware.

75 FR 66680 - Defense Federal Acquisition Regulation Supplement (DFARS); Continuation of Essential Contractor...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

...-AG52 Defense Federal Acquisition Regulation Supplement (DFARS); Continuation of Essential Contractor... that contractors providing essential contractor services, as determined by the requiring activity..., implementing the requirements of DoDI 3020.37, Continuation of Essential DoD Contractor Services During Crises...

48 CFR 52.236-23 - Responsibility of the Architect-Engineer Contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Architect-Engineer Contractor. 52.236-23 Section 52.236-23 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-23 Responsibility of the Architect-Engineer Contractor. As prescribed in 36.609-2(b), insert the following clause: Responsibility of the Architect-Engineer Contractor (APR 1984) (a...

48 CFR 52.236-23 - Responsibility of the Architect-Engineer Contractor.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Architect-Engineer Contractor. 52.236-23 Section 52.236-23 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-23 Responsibility of the Architect-Engineer Contractor. As prescribed in 36.609-2(b), insert the following clause: Responsibility of the Architect-Engineer Contractor (APR 1984) (a...

48 CFR 52.236-23 - Responsibility of the Architect-Engineer Contractor.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Architect-Engineer Contractor. 52.236-23 Section 52.236-23 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-23 Responsibility of the Architect-Engineer Contractor. As prescribed in 36.609-2(b), insert the following clause: Responsibility of the Architect-Engineer Contractor (APR 1984) (a...

48 CFR 52.236-23 - Responsibility of the Architect-Engineer Contractor.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Architect-Engineer Contractor. 52.236-23 Section 52.236-23 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-23 Responsibility of the Architect-Engineer Contractor. As prescribed in 36.609-2(b), insert the following clause: Responsibility of the Architect-Engineer Contractor (APR 1984) (a...

48 CFR 52.236-23 - Responsibility of the Architect-Engineer Contractor.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Architect-Engineer Contractor. 52.236-23 Section 52.236-23 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-23 Responsibility of the Architect-Engineer Contractor. As prescribed in 36.609-2(b), insert the following clause: Responsibility of the Architect-Engineer Contractor (APR 1984) (a...

MacIntyre's Revolutionary Aristotelian Philosophy and His Idea of an Educated Public Revisited

ERIC Educational Resources Information Center

Macallister, James

2016-01-01

In this article I revisit MacIntyre's lecture on the idea of an educated public. I argue that the full significance of MacIntyre's views on the underlying purposes of universities only become clear when his lecture on the educated public is situated in the context of his wider 'revolutionary Aristotelian' philosophical project. I claim that for…

Contractors Road Heavy Equipment Area SWMU 055 Corrective Measures Implementation Progress Report

NASA Technical Reports Server (NTRS)

Dorman, Lane

2015-01-01

This Corrective Measures Implementation (CMI) Progress Report, Revision 1, for Contractor's Road Heavy Equipment (CRHE) Area Solid Waste Management Unit (SWMU) Number 055 was prepared by Geosyntec Consultants (Geosyntec) for the National Aeronautics and Space Administration (NASA) under contract number NNK09CA02B, Delivery Order NNK09CA62D and Project Number PCN ENV-2324. This CMI Progress Report documents: (i) activities conducted as part of supplemental assessment activities completed from June 2009 through November 2014; (ii) Engineering Evaluation (EE) Advanced Data Packages (ADPs); and (iii) recommendations for future activities related to corrective measures at the Site.

78 FR 30233 - Defense Federal Acquisition Regulation Supplement; Government Support Contractor Access to...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... Number 0750-AG38 Defense Federal Acquisition Regulation Supplement; Government Support Contractor Access... Government support contractors to have access to proprietary technical data belonging to prime contractors and other third parties, provided that the technical data owner may require the support contractor to...