Science.gov

Sample records for administrative cost limit

  1. 45 CFR 2540.110 - Limitation on use of Corporation funds for administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... administrative costs. 2540.110 Section 2540.110 Public Welfare Regulations Relating to Public Welfare (Continued... Corporation will approve one of the following methods in the award document: (i) Limit the amount or rate of... Federal awards will be limited to this method; and (B) Unreimbursed indirect costs may be applied...

  2. 20 CFR 641.867 - What are the limitations on the amount of SCSEP administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false What are the limitations on the amount of SCSEP administrative costs? 641.867 Section 641.867 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT...

  3. 20 CFR 641.867 - What are the limitations on the amount of SCSEP administrative costs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false What are the limitations on the amount of SCSEP administrative costs? 641.867 Section 641.867 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT...

  4. 20 CFR 667.210 - What administrative cost limits apply to Workforce Investment Act title I grants?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INVESTMENT ACT Administrative Rules, Costs and Limitations § 667.210 What administrative cost limits apply to... be identified in the grant or contract award document. (c) In a One-Stop environment,...

  5. 45 CFR 1301.32 - Limitations on costs of development and administration of a Head Start program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE... 45 Public Welfare 4 2010-10-01 2010-10-01 false Limitations on costs of development and... and General Administration § 1301.32 Limitations on costs of development and administration of a...

  6. 45 CFR 1301.32 - Limitations on costs of development and administration of a Head Start program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE... 45 Public Welfare 4 2012-10-01 2012-10-01 false Limitations on costs of development and... and General Administration § 1301.32 Limitations on costs of development and administration of a...

  7. 45 CFR 1301.32 - Limitations on costs of development and administration of a Head Start program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE... 45 Public Welfare 4 2011-10-01 2011-10-01 false Limitations on costs of development and... and General Administration § 1301.32 Limitations on costs of development and administration of a...

  8. 45 CFR 1301.32 - Limitations on costs of development and administration of a Head Start program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE... 45 Public Welfare 4 2013-10-01 2013-10-01 false Limitations on costs of development and... and General Administration § 1301.32 Limitations on costs of development and administration of a...

  9. 45 CFR 1301.32 - Limitations on costs of development and administration of a Head Start program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE... 45 Public Welfare 4 2014-10-01 2014-10-01 false Limitations on costs of development and... and General Administration § 1301.32 Limitations on costs of development and administration of a...

  10. 45 CFR 286.55 - What types of costs are subject to the administrative cost limit on Tribal Family Assistance...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR... tracking, data entry and monitoring, including personnel and other costs associated with the...

  11. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Administrative costs. 96.88 Section 96.88 Public... Assistance Program § 96.88 Administrative costs. (a) Costs of planning and administration. Any expenditure... be included in determining administrative costs subject to the statutory limitation on...

  12. 20 CFR 641.870 - Under what circumstances may the administrative cost limitation be increased?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM... operation requirements imposed by the Department; (ii) The number of community service assignment positions... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Under what circumstances may...

  13. 20 CFR 641.870 - Under what circumstances may the administrative cost limitation be increased?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM... operation requirements imposed by the Department; (ii) The number of community service assignment positions... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Under what circumstances may...

  14. 20 CFR 632.174 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Administrative costs. 632.174 Section 632.174 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN... Administrative costs. Administrative costs for this subpart are limited to and shall not exceed 20 percent of...

  15. 45 CFR 286.55 - What types of costs are subject to the administrative cost limit on Tribal Family Assistance...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS Tribal TANF Funding... subject to the limit determined under § 286.50. (b) Information technology and computerization for..., administering, monitoring, and controlling a sample are not inherent parts of information technology...

  16. 45 CFR 286.55 - What types of costs are subject to the administrative cost limit on Tribal Family Assistance...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS Tribal TANF Funding... subject to the limit determined under § 286.50. (b) Information technology and computerization for..., administering, monitoring, and controlling a sample are not inherent parts of information technology...

  17. 45 CFR 286.55 - What types of costs are subject to the administrative cost limit on Tribal Family Assistance...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS Tribal TANF Funding... subject to the limit determined under § 286.50. (b) Information technology and computerization for..., administering, monitoring, and controlling a sample are not inherent parts of information technology...

  18. 45 CFR 286.55 - What types of costs are subject to the administrative cost limit on Tribal Family Assistance...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS Tribal TANF Funding... subject to the limit determined under § 286.50. (b) Information technology and computerization for..., administering, monitoring, and controlling a sample are not inherent parts of information technology...

  19. 20 CFR 667.210 - What administrative cost limits apply to Workforce Investment Act title I grants?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reserve for Statewide activities, the State may spend up to five percent (5%) of the amount allotted under... reserved for local administrative costs needs to be allocated back to the individual funding streams....

  20. 20 CFR 632.263 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Administrative costs. 632.263 Section 632.263... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.263 Administrative costs. Administrative costs for this subpart are limited to and shall not exceed 20 percent of the funds available....

  1. 45 CFR 263.13 - Is there a limit on the amount of Federal TANF funds that a State may spend on administrative costs?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Is there a limit on the amount of Federal TANF funds that a State may spend on administrative costs? 263.13 Section 263.13 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND...

  2. 20 CFR 668.825 - Does the WIA administrative cost limit for States and local areas apply to section 166 grants?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Does the WIA administrative cost limit for States and local areas apply to section 166 grants? 668.825 Section 668.825 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN...

  3. 20 CFR 668.825 - Does the WIA administrative cost limit for States and local areas apply to section 166 grants?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Does the WIA administrative cost limit for States and local areas apply to section 166 grants? 668.825 Section 668.825 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN...

  4. 20 CFR 668.825 - Does the WIA administrative cost limit for States and local areas apply to section 166 grants?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Does the WIA administrative cost limit for States and local areas apply to section 166 grants? 668.825 Section 668.825 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN...

  5. 20 CFR 645.235 - What types of activities are subject to the administrative cost limit on Welfare-to-Work grants?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Although administrative in nature, costs of information technology—computer hardware and software—needed... information, including job listing information, job skills information, and demand occupation information; and...) Developing systems and procedures, including information systems, required for these administrative......

  6. 20 CFR 645.235 - What types of activities are subject to the administrative cost limit on Welfare-to-Work grants?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Although administrative in nature, costs of information technology—computer hardware and software—needed... information, including job listing information, job skills information, and demand occupation information; and...) Developing systems and procedures, including information systems, required for these administrative......

  7. 20 CFR 645.235 - What types of activities are subject to the administrative cost limit on Welfare-to-Work grants?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Although administrative in nature, costs of information technology—computer hardware and software—needed... information, including job listing information, job skills information, and demand occupation information; and...) Developing systems and procedures, including information systems, required for these administrative......

  8. 20 CFR 645.235 - What types of activities are subject to the administrative cost limit on Welfare-to-Work grants?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Although administrative in nature, costs of information technology—computer hardware and software—needed... information, including job listing information, job skills information, and demand occupation information; and...) Developing systems and procedures, including information systems, required for these administrative......

  9. 24 CFR 583.135 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Administrative costs. 583.135... Administrative costs. (a) General. Up to five percent of any grant awarded under this part may be used for the purpose of paying costs of administering the assistance. (b) Administrative costs. Administrative...

  10. 45 CFR 1336.71 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Administrative costs. 1336.71 Section 1336.71... Administrative costs. Reasonable administrative costs of the RLF may be paid out of the loan fund. The grant award agreement between the Loan Administrator and ANA will set forth the allowable administrative...

  11. 20 CFR 645.235 - What types of activities are subject to the administrative cost limit on Welfare-to-Work grants?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Although administrative in nature, costs of information technology—computer hardware and software—needed... activities or the overall management of the WtW system; and (5) Costs of information systems related to... WtW including: (i) Accounting, budgeting, financial and cash management functions; (ii)...

  12. 24 CFR 511.71 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Administrative costs. 511.71... Administration § 511.71 Administrative costs. (a) Maximum amount. Any grantee may use not to exceed 10 percent of... years for administrative costs eligible under paragraphs (b) and (c) of this section. Eligible...

  13. Personnel administration can act on cost containment.

    PubMed

    Adams, J

    1980-01-01

    Hosiptal personnel administration programs have the potential to contain costs in a variety of areas, including human resources management, payroll costs, benefits costs, labor turnover, and recruitment costs. Recognizing this, the Maine Society for Hospital Personnel Administration presented a seminar and prepared a guide for trustees and administrators on the role that personnel administration can play in the Voluntary Effort to contain costs. The following article is an adaptation of the information included in the seminar and guide.

  14. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Administrative and planning costs... Administrative and planning costs. Up to such amount as HUD may authorize, or such other limit as may be... planning expenses of the DHHL relating to carrying out the Act and this part and activities assisted...

  15. 45 CFR 149.115 - Cost threshold and cost limit.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Cost threshold and cost limit. 149.115 Section 149... REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reinsurance Amounts § 149.115 Cost threshold and cost limit. The following cost threshold and cost limits apply individually, to each early retiree as...

  16. Administrative costs in selected industrialized countries

    PubMed Central

    Poullier, Jean-Pierre

    1992-01-01

    The costs of health administration are compared across several countries, accompanied by discussion of some of the variations in the definition of health administration. The influence of American health accounting on other countries is examined, and findings are presented regarding the relative costs of insurance-based and direct-delivery systems. Data are presented on health administrative spending providing gross as well as per capita measures. PMID:10122004

  17. 20 CFR 632.263 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Administrative costs. 632.263 Section 632.263 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.263 Administrative...

  18. 24 CFR 511.71 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DEVELOPMENT SLUM CLEARANCE AND URBAN RENEWAL RENTAL REHABILITATON GRANT PROGRAM Grant Administration § 511.71... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Administrative costs. 511.71 Section 511.71 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  19. 24 CFR 511.71 - Administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... DEVELOPMENT SLUM CLEARANCE AND URBAN RENEWAL RENTAL REHABILITATION GRANT PROGRAM Grant Administration § 511.71... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Administrative costs. 511.71 Section 511.71 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  20. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  1. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Welfare Department of Health and Human Services GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  2. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  3. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  4. 45 CFR 98.52 - Administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.52 Administrative costs. (a) Not more than five percent of...) Planning, developing, and designing the Child Care and Development Fund program; (ii) Providing...

  5. Administrative Costs of Education Voucher Programs.

    ERIC Educational Resources Information Center

    Hill, Paul T.

    This paper focuses on the administrative costs of vouchers programs. It considers the tasks that public and private agencies must undertake and estimates the administrative burdens and cash flow that local programs create. It assumes that all voucher programs, including those meant in part to reduce overcrowding, will be voluntary. The paper…

  6. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Administrative costs. 96.88 Section 96.88 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of...

  7. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Administrative costs. 96.88 Section 96.88 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of...

  8. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Administrative costs. 96.88 Section 96.88 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of...

  9. 45 CFR 96.88 - Administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Administrative costs. 96.88 Section 96.88 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Low-income Home Energy... planning and administering the low-income home energy assistance program shall be 20 percent of...

  10. Why Block Grants Should Increase Administrative Costs.

    ERIC Educational Resources Information Center

    Baker, Keith

    1983-01-01

    Federal education programs increase costs because they attach fewer strings to funds than state or local grants, and this is likely to lead to administrative empire-building. Bureaucracy tends pathologically as it grows to generate more work for itself independent of true administrative needs. Some policy implications are drawn. (MJL)

  11. 20 CFR 631.62 - Cost limitations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Cost limitations. 631.62 Section 631.62... Reserve Account Funds § 631.62 Cost limitations. The expenditure of funds provided to grantees under this subpart shall be consistent with the cost limitations specified in the grant. Applicants for grants...

  12. 24 CFR 511.71 - Administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... URBAN DEVELOPMENT SLUM CLEARANCE AND URBAN RENEWAL RENTAL REHABILITATION GRANT PROGRAM Grant... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Administrative costs. 511.71 Section 511.71 Housing and Urban Development Regulations Relating to Housing and Urban...

  13. 24 CFR 511.71 - Administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... URBAN DEVELOPMENT SLUM CLEARANCE AND URBAN RENEWAL RENTAL REHABILITATION GRANT PROGRAM Grant... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Administrative costs. 511.71 Section 511.71 Housing and Urban Development Regulations Relating to Housing and Urban...

  14. 45 CFR 263.13 - Is there a limit on the amount of Federal TANF funds that a State may spend on administrative costs?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN...) Expenditures on the information technology and computerization needed for tracking and monitoring required by..., support or operate the portions of information technology or computer systems used for tracking...

  15. 42 CFR 409.46 - Allowable administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... billable include, but are not limited to, the following: (a) Registered nurse initial evaluation visits. Initial evaluation visits by a registered nurse for the purpose of assessing a beneficiary's health needs... be an administrative cost. (b) Visits by registered nurses or qualified professionals for...

  16. 42 CFR 409.46 - Allowable administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... billable include, but are not limited to, the following: (a) Registered nurse initial evaluation visits. Initial evaluation visits by a registered nurse for the purpose of assessing a beneficiary's health needs... be an administrative cost. (b) Visits by registered nurses or qualified professionals for...

  17. 42 CFR 409.46 - Allowable administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... billable include, but are not limited to, the following: (a) Registered nurse initial evaluation visits. Initial evaluation visits by a registered nurse for the purpose of assessing a beneficiary's health needs... be an administrative cost. (b) Visits by registered nurses or qualified professionals for...

  18. 42 CFR 409.46 - Allowable administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... billable include, but are not limited to, the following: (a) Registered nurse initial evaluation visits. Initial evaluation visits by a registered nurse for the purpose of assessing a beneficiary's health needs... be an administrative cost. (b) Visits by registered nurses or qualified professionals for...

  19. 42 CFR 409.46 - Allowable administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... billable include, but are not limited to, the following: (a) Registered nurse initial evaluation visits. Initial evaluation visits by a registered nurse for the purpose of assessing a beneficiary's health needs... be an administrative cost. (b) Visits by registered nurses or qualified professionals for...

  20. 47 CFR 52.17 - Costs of number administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Costs of number administration. 52.17 Section... (CONTINUED) NUMBERING Administration § 52.17 Costs of number administration. All telecommunications carriers... efficient administration of the number administration cost recovery. (c) For the purposes of this...

  1. 45 CFR 63.18 - Limitations on costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Limitations on costs. 63.18 Section 63.18 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED BY THE OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions § 63.18 Limitations...

  2. 45 CFR 63.18 - Limitations on costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Limitations on costs. 63.18 Section 63.18 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED BY THE OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions § 63.18 Limitations...

  3. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that is...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the...

  4. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that is...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the...

  5. 26 CFR 301.7430-4 - Reasonable administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... witnesses; (iii) Reasonable costs of any study, analysis, engineering report, test or project that is...) PROCEDURE AND ADMINISTRATION PROCEDURE AND ADMINISTRATION Judicial Proceedings Civil Actions by the...

  6. 45 CFR 149.115 - Cost threshold and cost limit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Cost threshold and cost limit. 149.115 Section 149.115 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS... percentage increase in the Medical Care Component of the Consumer Price Index for all urban...

  7. 45 CFR 149.115 - Cost threshold and cost limit.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Cost threshold and cost limit. 149.115 Section 149.115 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS... percentage increase in the Medical Care Component of the Consumer Price Index for all urban...

  8. Administration knowledge of economic costs of foreign policy export controls

    SciTech Connect

    Not Available

    1983-09-02

    The Export Administration Act of 1979 requires consultation, as appropriate, with businesses affected by proposed controls and consideration of the controls economic impact. GAO found that although there was minimal formal business consultation, the business community and the Commerce and State Departments did provide decision-makers with the essential economic arguments against the use of export controls. Administration economic analyses usually did not provide estimates of the controls indirect effects, but important limits exist to Commerce's ability to better quantify such economic costs. GAO's review does not support the conclusion that the administration might have acted differently had it been aware of the total economic costs, and it shifts the debate back to the usefulness of such foreign policy controls.

  9. 24 CFR 1003.206 - Program administration costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Program administration costs. 1003... Eligible Activities § 1003.206 Program administration costs. ICDBG funds may be used for the payment of... to undertake a specific funded activity are also not considered program administration costs....

  10. 29 CFR 20.59 - Assessment of administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... because it became delinquent. Calculation of administrative costs shall be based on cost analyses... delinquency. (c) The Chief Financial Officer shall issue each year a schedule providing the costs...

  11. 38 CFR 62.70 - Financial management and administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... management of the program. These costs will include the administrative costs, both direct and indirect, of... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Financial management and administrative costs. 62.70 Section 62.70 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS...

  12. 38 CFR 62.70 - Financial management and administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... management of the program. These costs will include the administrative costs, both direct and indirect, of... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Financial management and administrative costs. 62.70 Section 62.70 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS...

  13. 38 CFR 62.70 - Financial management and administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... management of the program. These costs will include the administrative costs, both direct and indirect, of... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Financial management and administrative costs. 62.70 Section 62.70 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS...

  14. 38 CFR 62.70 - Financial management and administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... management of the program. These costs will include the administrative costs, both direct and indirect, of... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Financial management and administrative costs. 62.70 Section 62.70 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS...

  15. 24 CFR 92.207 - Eligible administrative and planning costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... planning costs. 92.207 Section 92.207 Housing and Urban Development Office of the Secretary, Department of... Prohibited Activities § 92.207 Eligible administrative and planning costs. A participating jurisdiction may expend, for payment of reasonable administrative and planning costs of the HOME program and ADDI,...

  16. 76 FR 74806 - Adjustment of the Amount of an Administrative Costs Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... Bureau of Reclamation Adjustment of the Amount of an Administrative Costs Assessment AGENCY: Bureau of... decreasing the amount of the administrative costs assessment set forth in the Acreage Limitation Rules and Regulations (Regulations), 43 CFR part 426. Based on our latest required review, the current...

  17. 5 CFR 179.214 - Interest, penalties and administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Interest, penalties and administrative costs. 179.214 Section 179.214 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Salary Offset § 179.214 Interest, penalties and administrative...

  18. 24 CFR 1003.206 - Program administration costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of such activities. In addition, technical assistance costs associated with developing the capacity... URBAN DEVELOPMENT COMMUNITY DEVELOPMENT BLOCK GRANTS FOR INDIAN TRIBES AND ALASKA NATIVE VILLAGES... reasonable administrative costs and carrying charges related to the planning and execution of...

  19. Administrative Malpractice: The Limits of Common Sense

    ERIC Educational Resources Information Center

    Bogue, E. Grady

    1978-01-01

    An administrator with a hybrid disposition, part scholar and part riverboat gambler, may serve more effectively than either model alone, suggests this executive of the Tennessee Higher Education Commission. Many academic administrators try to live by common sense, which is often yesterday's heresy. (Author/LBH)

  20. 45 CFR 607.12 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Interest, penalties, and administrative costs. 607.12 Section 607.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION SALARY OFFSET § 607.12 Interest, penalties, and administrative costs. Charges may be assessed on...

  1. 45 CFR 607.12 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Interest, penalties, and administrative costs. 607.12 Section 607.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION SALARY OFFSET § 607.12 Interest, penalties, and administrative costs. Charges may be assessed on...

  2. 45 CFR 607.12 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Interest, penalties, and administrative costs. 607.12 Section 607.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION SALARY OFFSET § 607.12 Interest, penalties, and administrative costs. Charges may be assessed on...

  3. 45 CFR 2521.95 - To what extent may I use grant funds for administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... administrative costs? 2521.95 Section 2521.95 Public Welfare Regulations Relating to Public Welfare (Continued... Corporation will approve one of the following methods in the award document: (1) Limit the amount or rate of... Federal awards will be limited to this method; and (ii) Unreimbursed indirect costs may be applied...

  4. 7 CFR 277.9 - Administrative costs principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administrative costs principles. 277.9 Section 277.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... households for Food Stamp Program benefits are allowable costs for FNS reimbursement. (c) When costs...

  5. 48 CFR 252.236-7006 - Cost limitation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Cost limitation. 252.236... Clauses 252.236-7006 Cost limitation. As prescribed in 236.570(b)(4), use the following provision: Cost Limitation (JAN 1997) (a) Certain items in this solicitation are subject to statutory cost limitations....

  6. 24 CFR 1003.206 - Program administration costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Eligible Activities § 1003.206 Program administration costs. ICDBG funds may be used for the payment of... this section and in § 1003.205—Eligible planning, urban environmental design and policy-planning... official business in carrying out the program; (3) Administrative services performed under third...

  7. Pupil Transportation Guide: Cost Analysis, Service Options, and Contract Administration.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento.

    Designed to help school administrators improve the efficiency of pupil transportation programs and control costs, this guide provides detailed guidance on how to collect and analyze costs, assess the effects of service levels and policies, and develop and administer a pupil transportation contract. Following an introductory chapter, part I…

  8. 43 CFR 426.20 - Assessment of administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... costs. (a) Assessment of administrative costs for delivery of water to ineligible land. Reclamation will... delivers irrigation water to land that was ineligible because the landholders did not submit certification or reporting forms prior to the receipt of irrigation water in accordance with § 426.18; or...

  9. 24 CFR 578.59 - Project administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Activities and UFA costs, for the payment of project administrative costs related to the planning and... carrying out the environmental review responsibilities under § 578.31. (b) Sharing requirement. (1) UFAs. If the recipient is a UFA that carries out a project, it may use up to 10 percent of the grant...

  10. 24 CFR 578.59 - Project administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Activities and UFA costs, for the payment of project administrative costs related to the planning and... carrying out the environmental review responsibilities under § 578.31. (b) Sharing requirement. (1) UFAs. If the recipient is a UFA that carries out a project, it may use up to 10 percent of the grant...

  11. 20 CFR 641.859 - What other special rules govern the classification of costs as administrative costs or program...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... classification of costs as administrative costs or program costs? 641.859 Section 641.859 Employees' Benefits... EMPLOYMENT PROGRAM Administrative Requirements § 641.859 What other special rules govern the classification of costs as administrative costs or program costs? (a) Recipients and subrecipients must comply...

  12. Assessing administrative costs of mental health and substance abuse services.

    PubMed

    Broyles, Robert W; Narine, Lutchmie; Robertson, Madeline J

    2004-05-01

    Increasing competition in the market for mental health and substance abuse MHSA services and the potential to realize significant administrative savings have created an imperative to monitor, evaluate, and control spending on administrative functions. This paper develops a generic model that evaluates spending on administrative personnel by a group of providers. The precision of the model is demonstrated by examining a set of data assembled from five MHSA service providers. The model examines a differential cost construction derived from inter-facility comparisons of administrative expenses. After controlling for the scale of operations, the results enable MHSA programs to control the efficiency of administrative personnel and related rates of compensation. The results indicate that the efficiency of using the administrative complement and the scale of operations represent the lion's share of the total differential cost. The analysis also indicates that a modest improvement in the use of administrative personnel results in substantial cost savings, an increase in the net cash flow derived from operations, an improvement in the fiscal performance of the provider, and a decline in opportunity costs that assume the form of foregone direct patient care.

  13. 78 FR 8389 - Natural Gas Pipelines; Project Cost and Annual Limits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... Energy Regulatory Commission 18 CFR Part 157 Natural Gas Pipelines; Project Cost and Annual Limits AGENCY... publishes the project cost and annual limits for natural gas pipelines blanket construction certificates for... CFR Part 157 Administrative practice and procedure, Natural Gas, Reporting and...

  14. 75 FR 8245 - Natural Gas Pipelines; Project Cost and Annual Limits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... Energy Regulatory Commission 18 CFR Part 157 Natural Gas Pipelines; Project Cost and Annual Limits...) computes and publishes the project cost and annual limits for natural gas pipelines blanket construction... Part 157 Administrative practice and procedure, Natural gas, Reporting and recordkeeping...

  15. 20 CFR 631.62 - Cost limitations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... THE JOB TRAINING PARTNERSHIP ACT Federal Delivery of Dislocated Worker Services Through National... not adequately justify to the Grant Officer's satisfaction the costs to be incorporated into the...

  16. 20 CFR 631.62 - Cost limitations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... THE JOB TRAINING PARTNERSHIP ACT Federal Delivery of Dislocated Worker Services Through National... not adequately justify to the Grant Officer's satisfaction the costs to be incorporated into the...

  17. 42 CFR 413.35 - Limitations on coverage of costs: Charges to beneficiaries if cost limits are applied to services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., subject to validation by the intermediary, will estimate the current cost of the service to which a limit... when there is no second preceding period) exceed the current cost limits. (Data from the most recently... 42 Public Health 2 2010-10-01 2010-10-01 false Limitations on coverage of costs: Charges...

  18. 45 CFR 2521.45 - What are the limitations on the Federal government's share of program costs?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... administration costs. (1) You may provide your share of program operating costs with cash, including other...'s share of program costs? 2521.45 Section 2521.45 Public Welfare Regulations Relating to Public... limitations on the Federal government's share of program costs? The limitations on the Federal...

  19. 77 FR 38802 - Proposed CERCLA Administrative Cost Recovery Settlement; Standex International Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Standex International Corporation AGENCY... a proposed administrative settlement for recovery of past response costs concerning the Trinity... hereby given of a proposed administrative settlement for recovery of past response costs concerning...

  20. A comparison of hospital administrative costs in eight nations: US costs exceed all others by far.

    PubMed

    Himmelstein, David U; Jun, Miraya; Busse, Reinhard; Chevreul, Karine; Geissler, Alexander; Jeurissen, Patrick; Thomson, Sarah; Vinet, Marie-Amelie; Woolhandler, Steffie

    2014-09-01

    A few studies have noted the outsize administrative costs of US hospitals, but no research has compared these costs across multiple nations with various types of health care systems. We assembled a team of international health policy experts to conduct just such a challenging analysis of hospital administrative costs across eight nations: Canada, England, Scotland, Wales, France, Germany, the Netherlands, and the United States. We found that administrative costs accounted for 25.3 percent of total US hospital expenditures--a percentage that is increasing. Next highest were the Netherlands (19.8 percent) and England (15.5 percent), both of which are transitioning to market-oriented payment systems. Scotland and Canada, whose single-payer systems pay hospitals global operating budgets, with separate grants for capital, had the lowest administrative costs. Costs were intermediate in France and Germany (which bill per patient but pay separately for capital projects) and in Wales. Reducing US per capita spending for hospital administration to Scottish or Canadian levels would have saved more than $150 billion in 2011. This study suggests that the reduction of US administrative costs would best be accomplished through the use of a simpler and less market-oriented payment scheme.

  1. 22 CFR 309.5 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... 309.5 Section 309.5 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.5 Interest... accordance with FCCS, Peace Corps will assess: (1) Interest on unpaid debts in accordance with 31 CFR 901.9...) Waiver. Peace Corps will consider waiver of interest, penalties and/or administrative costs in...

  2. 22 CFR 309.5 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... 309.5 Section 309.5 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.5 Interest... accordance with FCCS, Peace Corps will assess: (1) Interest on unpaid debts in accordance with 31 CFR 901.9...) Waiver. Peace Corps will consider waiver of interest, penalties and/or administrative costs in...

  3. 22 CFR 309.5 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... 309.5 Section 309.5 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.5 Interest... accordance with FCCS, Peace Corps will assess: (1) Interest on unpaid debts in accordance with 31 CFR 901.9...) Waiver. Peace Corps will consider waiver of interest, penalties and/or administrative costs in...

  4. 22 CFR 309.5 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... 309.5 Section 309.5 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.5 Interest... accordance with FCCS, Peace Corps will assess: (1) Interest on unpaid debts in accordance with 31 CFR 901.9...) Waiver. Peace Corps will consider waiver of interest, penalties and/or administrative costs in...

  5. 22 CFR 309.5 - Interest, penalties, and administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... 309.5 Section 309.5 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.5 Interest... accordance with FCCS, Peace Corps will assess: (1) Interest on unpaid debts in accordance with 31 CFR 901.9...) Waiver. Peace Corps will consider waiver of interest, penalties and/or administrative costs in...

  6. Of Dirty Sheets and Worse: Administration Costs and Staffing Matters.

    ERIC Educational Resources Information Center

    Keigher, Sharon M.

    1993-01-01

    Considers article written by professor of social welfare in 1981 in which job security of social workers is addressed. Compares views expressed in 1981 with situation faced by social workers today. Considers danger of administration costs resulting in short-staffing of hospitals serving the poor and discusses case of 22-year-old obstetrics patient…

  7. 40 CFR 13.11 - Interest, penalty and administrative costs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Interest, penalty and administrative costs. 13.11 Section 13.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS... inaction, and without fault by the debtor; or (iii) Collection of these charges would be against equity...

  8. 40 CFR 13.11 - Interest, penalty and administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Interest, penalty and administrative costs. 13.11 Section 13.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS... inaction, and without fault by the debtor; or (iii) Collection of these charges would be against equity...

  9. 40 CFR 13.11 - Interest, penalty and administrative costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Interest, penalty and administrative costs. 13.11 Section 13.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS... inaction, and without fault by the debtor; or (iii) Collection of these charges would be against equity...

  10. 40 CFR 13.11 - Interest, penalty and administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Interest, penalty and administrative costs. 13.11 Section 13.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS... inaction, and without fault by the debtor; or (iii) Collection of these charges would be against equity...

  11. 40 CFR 13.11 - Interest, penalty and administrative costs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Interest, penalty and administrative costs. 13.11 Section 13.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS... inaction, and without fault by the debtor; or (iii) Collection of these charges would be against equity...

  12. 42 CFR 413.30 - Limitations on payable costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... current costs. CMS adjusts current and past period data to arrive at estimated costs for the prospective... 42 Public Health 2 2010-10-01 2010-10-01 false Limitations on payable costs. 413.30 Section 413.30... PROGRAM PRINCIPLES OF REASONABLE COST REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE...

  13. 32 CFR 3.6 - Limitations on cost-sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... THAN CONTRACTS, GRANTS, OR COOPERATIVE AGREEMENTS FOR PROTOTYPE PROJECTS § 3.6 Limitations on cost... the performance of the OT agreement may not include costs that were incurred before the date on...

  14. 32 CFR 3.6 - Limitations on cost-sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... THAN CONTRACTS, GRANTS, OR COOPERATIVE AGREEMENTS FOR PROTOTYPE PROJECTS § 3.6 Limitations on cost... the performance of the OT agreement may not include costs that were incurred before the date on...

  15. 48 CFR 1832.705-270 - NASA clauses for limitation of cost or funds.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA clauses for limitation... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Contract Funding 1832.705-270 NASA clauses for limitation of cost or funds. (a) The contracting officer shall insert...

  16. 10 CFR 602.15 - Indirect cost limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Indirect cost limitations. 602.15 Section 602.15 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.15 Indirect cost limitations. Awards issued under this part for conferences...

  17. 42 CFR 413.30 - Limitations on payable costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Limitations on payable costs. 413.30 Section 413.30 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE... of needed health care services. CMS may establish estimated cost limits for direct or...

  18. 36 CFR 1206.45 - What rules govern subgrant distribution, cost sharing, grant administration, and reporting?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... distribution, cost sharing, grant administration, and reporting? 1206.45 Section 1206.45 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION GENERAL RULES NATIONAL HISTORICAL..., cost sharing, grant administration, and reporting? (a) The Commission will annually establish...

  19. Guidelines for Serving Students with Limited English Proficiency. Administrative Manual.

    ERIC Educational Resources Information Center

    Biagini, Joyce; And Others

    A revision of a manual first produced in 1980, this guide is designed to help local school districts in Minnesota meet the educational needs of their limited-English-proficient (LEP) students in academically and administratively expedient ways. The chapters in the manual, which correspond to topics pertinent to designing and maintaining an LEP…

  20. 42 CFR 413.30 - Limitations on payable costs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Limitations on payable costs. 413.30 Section 413.30 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE...

  1. 42 CFR 413.30 - Limitations on payable costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 2 2014-10-01 2014-10-01 false Limitations on payable costs. 413.30 Section 413.30 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE...

  2. 42 CFR 413.30 - Limitations on payable costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Limitations on payable costs. 413.30 Section 413.30 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE...

  3. 75 FR 21292 - Proposed CERCLA Administrative Cost Recovery Settlement Agreement; AVX Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed CERCLA Administrative Cost Recovery Settlement Agreement; AVX Corporation AGENCY... administrative settlement for recovery of projected future response oversight costs and performance of...

  4. 77 FR 69441 - Federal Acquisition Regulation; Information Collection; Cost Accounting Standards Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... Regulation; Information Collection; Cost Accounting Standards Administration AGENCY: Department of Defense...: Under the provisions of the Paperwork Reduction Act, the Regulatory Secretariat will be submitting to... approved information collection requirement concerning cost accounting standards administration....

  5. 43 CFR 429.18 - When do I have to pay the administrative costs?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true When do I have to pay the administrative costs? 429.18 Section 429.18 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF... Application Fees and Administrative Costs § 429.18 When do I have to pay the administrative costs?...

  6. 78 FR 18429 - Cost Recovery for Permit Processing, Administration, and Enforcement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... 30 CFR Parts 701, 736, 737 et al. Cost Recovery for Permit Processing, Administration, and... 701, 736, 737, 738, and 750 RIN 1029-AC65 Cost Recovery for Permit Processing, Administration, and... fees to recover the actual costs for permit review and administration and permit enforcement...

  7. Innovative Feed-In Tariff Designs that Limit Policy Costs

    SciTech Connect

    Kreycik, C.; Couture, T. D.; Cory, K. S.

    2011-06-01

    Feed-in tariffs (FITs) are the most prevalent renewable energy policy used globally to date, and there are many benefits to the certainty offered in the marketplace to reduce development risks and associated financing costs and to grow the renewable energy industry. However, concerns over escalating costs in jurisdictions with FIT policies have led to increased attention on cost control in renewable energy policy design. In recent years, policy mechanisms for containing FIT costs have become more refined, allowing policymakers to exert greater control on policy outcomes and on the resulting costs to ratepayers. As policymakers and regulators in the United States begin to explore the use of FITs, careful consideration must be given to the ways in which policy design can be used to balance the policies' advantages while bounding its costs. This report explores mechanisms that policymakers have implemented to limit FIT policy costs. If designed clearly and transparently, such mechanisms can align policymaker and market expectations for project deployment. Three different policy tools are evaluated: (1) caps, (2) payment level adjustment mechanisms, and (3) auction-based designs. The report employs case studies to explore the strengths and weaknesses of these three cost containment tools. These tools are then evaluated with a set of criteria including predictability for policymakers and the marketplace and the potential for unintended consequences.

  8. 24 CFR 891.140 - Development cost limits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Development cost limits. 891.140 Section 891.140 Housing and Urban Development Regulations Relating to Housing and Urban Development... AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM,...

  9. 24 CFR 891.853 - Development cost limits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Development cost limits. 891.853 Section 891.853 Housing and Urban Development Regulations Relating to Housing and Urban Development... AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM,...

  10. 32 CFR 644.521 - Limitations on clearance cost.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Limitations on clearance cost. 644.521 Section 644.521 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Clearance of Explosive Hazards and Other Contamination from...

  11. 32 CFR 644.521 - Limitations on clearance cost.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Limitations on clearance cost. 644.521 Section 644.521 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Clearance of Explosive Hazards and Other Contamination from...

  12. Space power using solar photovoltaic panels: costs and limitations

    SciTech Connect

    Williams, K.A.

    1986-03-01

    Solar photovoltaic panels (SPPs) have been suggested as a possible prime space power source for multi-kilowatt applications within a ballistic missile defense (BMD) system. As a first step in an attempt to assess the affordability of possible BMD space power sources, the limitations and costs of space power satellites using SSPs in conjunction with an electrochemical energy storage system have been investigated. Both high and low earth orbital missions are considered. An extensive literature search was conducted to determine values for the principal technology-driven performance and cost figures of merit. A small computer code was then developed to evaluate the total power cost, including launch, in dollars per watt of desired space power load. The unit costs obtained were found to be heavily influenced by the nature of the mission (altitude) and the attainable specific power for the two major system components.

  13. 26 CFR 301.7430-2 - Requirements and procedures for recovery of reasonable administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... administrative proceeding, then an affidavit that specialized skills and distinctive knowledge as described in... reasonable administrative costs. 301.7430-2 Section 301.7430-2 Internal Revenue INTERNAL REVENUE SERVICE... reasonable administrative costs. (a) Introduction. Section 7430(a)(1) provides for the recovery,...

  14. 42 CFR 413.35 - Limitations on coverage of costs: Charges to beneficiaries if cost limits are applied to services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... charge an individual entitled to benefits under Medicare for such more expensive items or services even... charges the provider is authorized to impose on individuals entitled to benefits under Medicare on account... beneficiaries if cost limits are applied to services. 413.35 Section 413.35 Public Health CENTERS FOR...

  15. 42 CFR 413.35 - Limitations on coverage of costs: Charges to beneficiaries if cost limits are applied to services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... charge an individual entitled to benefits under Medicare for such more expensive items or services even... charges the provider is authorized to impose on individuals entitled to benefits under Medicare on account... beneficiaries if cost limits are applied to services. 413.35 Section 413.35 Public Health CENTERS FOR...

  16. 42 CFR 413.35 - Limitations on coverage of costs: Charges to beneficiaries if cost limits are applied to services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... charge an individual entitled to benefits under Medicare for such more expensive items or services even... charges the provider is authorized to impose on individuals entitled to benefits under Medicare on account... beneficiaries if cost limits are applied to services. 413.35 Section 413.35 Public Health CENTERS FOR...

  17. 42 CFR 413.35 - Limitations on coverage of costs: Charges to beneficiaries if cost limits are applied to services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... charge an individual entitled to benefits under Medicare for such more expensive items or services even... charges the provider is authorized to impose on individuals entitled to benefits under Medicare on account... beneficiaries if cost limits are applied to services. 413.35 Section 413.35 Public Health CENTERS FOR...

  18. 47 CFR 27.1162 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 27... Cost-Sharing Policies Governing Microwave Relocation from the 2110-2150 Mhz and 2160-2200 Mhz Bands § 27.1162 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau,...

  19. 47 CFR 27.1178 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 27... Cost-Sharing Policies Governing Broadband Radio Service Relocation from the 2150-2160/62 Mhz Band § 27.1178 Administration of the Cost-Sharing Plan. The Wireless Telecommunications Bureau, under...

  20. 48 CFR 52.230-6 - Administration of Cost Accounting Standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Clauses 52.230-6 Administration of Cost Accounting Standards. As prescribed in 30.201-4(d)(1), insert the following clause: Administration of Cost Accounting Standards (JUN 2010) For the purpose of administering the Cost Accounting Standards (CAS) requirements under this contract, the Contractor shall take...

  1. 24 CFR 1006.230 - Administrative and planning costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... paragraphs (a)(1)(i) through (vi) of this section; (2) Travel costs incurred for official business in... maintenance (but not purchase) of office space. (b) Staff and overhead. Staff and overhead costs...

  2. What School Administrators Should Know about Inclusion and Its Costs.

    ERIC Educational Resources Information Center

    Pruslow, John T.

    2003-01-01

    Examines cost-effectiveness of school inclusion for special-needs students. Includes cost analysis of instructional personnel, impact on general education spending, transportation, and school space. Draws policy implications. (Contains 34 references.) (PKP)

  3. 42 CFR 417.564 - Apportionment and allocation of administrative and general costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... providing medical care. Enrollment, marketing, and other administrative and general costs that benefit the... bear a significant relationship to the services furnished, are not apportioned to Medicare...

  4. High feeding costs limit dive time in the largest whales.

    PubMed

    Acevedo-Gutiérrez, A; Croll, D A; Tershy, B R

    2002-06-01

    Large body size usually extends dive duration in air-breathing vertebrates. However, the two largest predators on earth, the blue whale (Balaenoptera musculus) and the fin whale (B. physalus), perform short dives for their size. Here, we test the hypothesis that the foraging behavior of these two species (lunge-feeding) is energetically expensive and limits their dive duration. We estimated the cost of lunge-feeding in both species using an approach that combined attaching time/depth recorders to seven blue whales and eight fin whales and comparing the collected dive information with predictions made by optimality models of dive behavior. We show that the rate at which whales recovered from a foraging dive was twice that of a non-foraging dive and that the cost of foraging relative to the cost of travel to and from the prey patch was 3.15 in blue whales (95 % CI 2.58-3.72) and 3.60 in fin whales (95 % CI 2.35-4.85). Whales foraged in small areas (<1 km(2)) and foraging bouts lasted more than one dive, indicating that prey did not disperse and thus that prey dispersal could not account for the limited dive durations of the whales. Despite the enormous size of blue whales and fin whales, the high energetic costs of lunge-feeding confine them to short durations of submergence and to areas with dense prey aggregations. As a corollary, because of their limited foraging time under water, these whales may be particularly vulnerable to perturbations in prey abundance.

  5. 20 CFR 632.39 - Administrative cost plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a Native American grantee may be accounted for separately and be allocated by title and program....39 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Administrative Standards and Procedures § 632.39...

  6. 20 CFR 632.39 - Administrative cost plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... a Native American grantee may be accounted for separately and be allocated by title and program....39 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Administrative Standards and Procedures § 632.39...

  7. Good agreement between questionnaire and administrative databases for health care use and costs in patients with osteoarthritis

    PubMed Central

    2011-01-01

    Background Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a partial representation of health care costs and have additional limitations. Patient-completed questionnaires may allow a broader representation of health care costs; however the validity and feasibility of such methods have not been firmly established. This study was conducted to assess the validity and feasibility of using a patient-completed questionnaire to capture health care use and costs for patients with osteoarthritis, and to compare the research costs of the data-capture methods. Methods We designed a patient questionnaire and applied it in a clinical trial. We captured equivalent data from four administrative databases. We evaluated aspects of the questionnaire's validity using sensitivity and specificity, Lin's concordance correlation coefficient (ρc), and Bland-Altman comparisons. Results The questionnaire's response rate was 89%. Acceptable sensitivity and specificity levels were found for all types of health care use. The numbers of visits and the majority of medications reported by patients were in agreement with the database-derived estimates (ρc > 0.40). Total cost estimates from the questionnaire agreed with those from the databases. Patient-reported co-payments agreed with administrative records with respect to GP office transactions, but not pharmaceutical co-payments. Research costs for the questionnaire-based method were less than one-third of the costs for the databases method. Conclusion A patient-completed questionnaire is feasible for capturing health care use and costs for patients with osteoarthritis, and data collected using it mostly agree with administrative databases. Caution should be exercised when applying unit costs and collecting co-payment data. PMID:21489280

  8. The administrative costs of community-based health insurance: a case study of the community health fund in Tanzania.

    PubMed

    Borghi, Josephine; Makawia, Suzan; Kuwawenaruwa, August

    2015-02-01

    Community-based health insurance expansion has been proposed as a financing solution for the sizable informal sector in low-income settings. However, there is limited evidence of the administrative costs of such schemes. We assessed annual facility and district-level costs of running the Community Health Fund (CHF), a voluntary health insurance scheme for the informal sector in a rural and an urban district from the same region in Tanzania. Information on resource use, CHF membership and revenue was obtained from district managers and health workers from two facilities in each district. The administrative cost per CHF member household and the cost to revenue ratio were estimated. Revenue collection was the most costly activity at facility level (78% of total costs), followed by stewardship and management (13%) and pooling of funds (10%). Stewardship and management was the main activity at district level. The administration cost per CHF member household ranged from USD 3.33 to USD 12.12 per year. The cost to revenue ratio ranged from 50% to 364%. The cost of administering the CHF was high relative to revenue generated. Similar studies from other settings should be encouraged.

  9. The administrative costs of community-based health insurance: a case study of the community health fund in Tanzania

    PubMed Central

    Borghi, Josephine; Makawia, Suzan; Kuwawenaruwa, August

    2015-01-01

    Community-based health insurance expansion has been proposed as a financing solution for the sizable informal sector in low-income settings. However, there is limited evidence of the administrative costs of such schemes. We assessed annual facility and district-level costs of running the Community Health Fund (CHF), a voluntary health insurance scheme for the informal sector in a rural and an urban district from the same region in Tanzania. Information on resource use, CHF membership and revenue was obtained from district managers and health workers from two facilities in each district. The administrative cost per CHF member household and the cost to revenue ratio were estimated. Revenue collection was the most costly activity at facility level (78% of total costs), followed by stewardship and management (13%) and pooling of funds (10%). Stewardship and management was the main activity at district level. The administration cost per CHF member household ranged from USD 3.33 to USD 12.12 per year. The cost to revenue ratio ranged from 50% to 364%. The cost of administering the CHF was high relative to revenue generated. Similar studies from other settings should be encouraged. PMID:24334331

  10. 77 FR 9652 - Proposed CERCLA Administrative Cost Recovery Settlement; Lake Linden Superfund Site in Lake...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Lake Linden Superfund Site in Lake Linden... Liability Act, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for recovery of past response costs concerning the Lake Linden Superfund Site in...

  11. 78 FR 40738 - Proposed CERCLA Administrative Cost Recovery Settlement; Double H Pesticide Burial Site

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Double H Pesticide Burial Site AGENCY... (CERCLA), notice is hereby given of a proposed administrative settlement for recovery of response costs... the EPA Hazardous Substance Superfund. Upon payment of this sum to EPA, the settling parties will...

  12. 75 FR 146 - Proposed Cercla Administrative Cost Recovery Settlement; David Benvenuti and Howe Cleaners, Howe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ...: E9-31176] ENVIRONMENTAL PROTECTION AGENCY [FRL-9099-6] Proposed Cercla Administrative Cost Recovery... (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for recovery of past costs concerning the Howe Cleaners Superfund Site in Barre, Vermont with the...

  13. 25 CFR 122.8 - Administrative costs for management of the fund.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Administrative costs for management of the fund. 122.8 Section 122.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES MANAGEMENT OF OSAGE JUDGMENT FUNDS FOR EDUCATION § 122.8 Administrative costs for management of the fund....

  14. 25 CFR 122.8 - Administrative costs for management of the fund.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Administrative costs for management of the fund. 122.8 Section 122.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES MANAGEMENT OF OSAGE JUDGMENT FUNDS FOR EDUCATION § 122.8 Administrative costs for management of the fund....

  15. 25 CFR 122.8 - Administrative costs for management of the fund.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Administrative costs for management of the fund. 122.8 Section 122.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES MANAGEMENT OF OSAGE JUDGMENT FUNDS FOR EDUCATION § 122.8 Administrative costs for management of the fund....

  16. 25 CFR 122.8 - Administrative costs for management of the fund.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Administrative costs for management of the fund. 122.8 Section 122.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES MANAGEMENT OF OSAGE JUDGMENT FUNDS FOR EDUCATION § 122.8 Administrative costs for management of the fund....

  17. 25 CFR 122.8 - Administrative costs for management of the fund.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Administrative costs for management of the fund. 122.8 Section 122.8 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES MANAGEMENT OF OSAGE JUDGMENT FUNDS FOR EDUCATION § 122.8 Administrative costs for management of the fund....

  18. 10 CFR 171.25 - Collection, interest, penalties, and administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Collection, interest, penalties, and administrative costs. 171.25 Section 171.25 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ANNUAL FEES FOR REACTOR... Collection, interest, penalties, and administrative costs. All annual fees in §§ 171.15 and 171.16 will...

  19. 10 CFR 171.25 - Collection, interest, penalties, and administrative costs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Collection, interest, penalties, and administrative costs. 171.25 Section 171.25 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ANNUAL FEES FOR REACTOR... Collection, interest, penalties, and administrative costs. All annual fees in §§ 171.15 and 171.16 will...

  20. 31 CFR Appendix I(f) to Part 13 - Estimated Overhead and Administrative Costs

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Estimated Overhead and Administrative Costs I(F) Appendix I(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. I(F) Appendix I(F) to Part 13—Estimated Overhead and Administrative Costs Date:...

  1. 31 CFR Appendix I(f) to Part 13 - Estimated Overhead and Administrative Costs

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Estimated Overhead and Administrative Costs I(F) Appendix I(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. I(F) Appendix I(F) to Part 13—Estimated Overhead and Administrative Costs Date:...

  2. 31 CFR Appendix II(f) to Part 13 - Overhead and Administrative Costs

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Overhead and Administrative Costs II(F) Appendix II(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. II(F) Appendix II(F) to Part 13—Overhead and Administrative Costs Date: Select Only...

  3. 31 CFR Appendix II(f) to Part 13 - Overhead and Administrative Costs

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Overhead and Administrative Costs II(F) Appendix II(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. II(F) Appendix II(F) to Part 13—Overhead and Administrative Costs Date: Select Only...

  4. 31 CFR Appendix I(f) to Part 13 - Estimated Overhead and Administrative Costs

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Estimated Overhead and Administrative Costs I(F) Appendix I(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. I(F) Appendix I(F) to Part 13—Estimated Overhead and Administrative Costs Date:...

  5. 31 CFR Appendix I(f) to Part 13 - Estimated Overhead and Administrative Costs

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Estimated Overhead and Administrative Costs I(F) Appendix I(F) to Part 13 Money and Finance: Treasury Office of the Secretary of the Treasury... Pt. 13, App. I(F) Appendix I(F) to Part 13—Estimated Overhead and Administrative Costs Date:...

  6. Average System Cost Methodology : Administrator's Record of Decision.

    SciTech Connect

    United States. Bonneville Power Administration.

    1984-06-01

    Significant features of average system cost (ASC) methodology adopted are: retention of the jurisdictional approach where retail rate orders of regulartory agencies provide primary data for computing the ASC for utilities participating in the residential exchange; inclusion of transmission costs; exclusion of construction work in progress; use of a utility's weighted cost of debt securities; exclusion of income taxes; simplification of separation procedures for subsidized generation and transmission accounts from other accounts; clarification of ASC methodology rules; more generous review timetable for individual filings; phase-in of reformed methodology; and each exchanging utility must file under the new methodology within 20 days of implementation by the Federal Energy Regulatory Commission of the ten major participating utilities, the revised ASC will substantially only affect three. (PSB)

  7. Optimal administrative scale for planning public services: a social cost model applied to Flemish hospital care.

    PubMed

    Blank, Jos L T; van Hulst, Bart

    2015-01-01

    In choosing the scale of public services, such as hospitals, both economic and public administrative considerations play important roles. The scale and the corresponding spatial distribution of public institutions have consequences for social costs, defined as the institutions' operating costs and the users' travel costs (which include the money and time costs). Insight into the relationship between scale and spatial distribution and social costs provides a practical guide for the best possible administrative planning level. This article presents a purely economic model that is suitable for deriving the optimal scale for public services. The model also reveals the corresponding optimal administrative planning level from an economic perspective. We applied this model to hospital care in Flanders for three different types of care. For its application, we examined the social costs of hospital services at different levels of administrative planning. The outcomes show that the social costs of rehabilitation in Flanders with planning at the urban level (38 areas) are 11% higher than those at the provincial level (five provinces). At the regional level (18 areas), the social costs of rehabilitation are virtually equal to those at the provincial level. For radiotherapy, there is a difference of 88% in the social costs between the urban and the provincial level. For general care, there are hardly any cost differences between the three administrative levels. Thus, purely from the perspective of social costs, rehabilitation should preferably be planned at the regional level, general services at the urban level and radiotherapy at the provincial level.

  8. 77 FR 64513 - Proposed Administrative Agreement for Collection of CERCLA Past Costs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... AGENCY Proposed Administrative Agreement for Collection of CERCLA Past Costs AGENCY: U.S Environmental Protection Agency (U.S. EPA). ACTION: Notice. Proposed CERCLA 122 Administrative Agreement. SUMMARY: U.S. EPA is proposing to execute an Administrative Agreement (Agreement) under Section 122 of CERCLA...

  9. The Obama administration's options for health care cost control: hope versus reality.

    PubMed

    Marmor, Theodore; Oberlander, Jonathan; White, Joseph

    2009-04-07

    Controlling the costs of medical care has long been an elusive goal in U.S. health policy. This article examines the options for health care cost control under the Obama administration. The authors argue that the administration's approach to health reform offers some potential for cost control but also embraces many strategies that are not likely to be successful. Lessons the United States can learn from other countries' experiences in constraining medical care spending are then explored.

  10. 24 CFR 905.314 - Cost and other limitations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... & Swift cost index for construction of “good” quality. HUD has the discretion to change the cost indices... index for construction of “average” quality and the Marshal & Swift cost index for construction of...

  11. 76 FR 26291 - Proposed CERCLA AdministrativeCost Recovery” Settlement; the Doe Run Resources Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed CERCLA Administrative ``Cost Recovery'' Settlement; the Doe Run Resources Corporation.... Francois Mining Area, St. Francois County, Missouri with the following settling party: The Doe...

  12. 75 FR 34448 - Proposed CERCLA Administrative Cost Recovery Settlement; Great Lakes Container Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Great Lakes Container Corporation... Lakes Container Corporation Superfund Site, located in Coventry Rhode Island with the settling parties...-1216. Comments should reference the Great Lakes Container Corporation Superfund Site, Coventry,...

  13. 76 FR 14968 - Proposed CERCLA Administrative Cost Recovery Settlement; Eugenio Painting Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Eugenio Painting Company AGENCY... following settling party: Eugenio Painting Company. The settlement requires the settling party to pay...

  14. 77 FR 42310 - Proposed CERCLA Administrative Cost Recovery Settlement; City of Middletown, CT and RLO...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ..., Inc., Omo Manufacturing Site, Middletown, CT AGENCY: Environmental Protection Agency. ACTION: Notice... administrative settlement for recovery of response costs under CERCLA, concerning the Omo Manufacturing Superfund... the Omo Manufacturing Superfund Site in Middletown, Connecticut with the following settling...

  15. 34 CFR 690.10 - Administrative cost allowance to participating schools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... General Definitions § 690.10 Administrative cost allowance to participating schools. (a) Subject to... make financial aid services available during times and in places that will most effectively...

  16. 78 FR 42944 - Proposed Administrative Cost Recovery Settlement Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ...: Environmental Protection Agency (EPA). ACTION: Notice; request for public comment. SUMMARY: In accordance with... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed Administrative Cost Recovery Settlement Under the Comprehensive Environmental...

  17. 20 CFR 641.856 - What functions and activities constitute costs of administration?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., including: (i) Accounting, budgeting, financial, and cash management functions; (ii) Procurement and... ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM... the direct provision of programmatic services specified in § 641.864. These costs may be...

  18. 76 FR 51029 - Proposed CERCLA Administrative Cost Recovery Settlement; Carpenter Avenue Mercury Site, Iron...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Carpenter Avenue Mercury Site, Iron... Mercury site in Iron Mountain, Dickenson County, Michigan with the following settling parties: The.... Comments should reference the Carpenter Avenue Mercury site, Iron Mountain, Dickenson County, Michigan...

  19. 20 CFR 641.876 - How will compliance with cost limitations and minimum expenditure levels be determined?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false How will compliance with cost limitations and minimum expenditure levels be determined? 641.876 Section 641.876 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE...

  20. 20 CFR 641.876 - How will compliance with cost limitations and minimum expenditure levels be determined?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false How will compliance with cost limitations and minimum expenditure levels be determined? 641.876 Section 641.876 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE...

  1. 75 FR 57272 - Proposed CERCLA Administrative Cost Recovery Settlement; Gilberts/Kedzie Site, Village of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Gilberts/Kedzie Site, Village of Gilberts..., as amended (``CERCLA''), 42 U.S.C. 9622(I), notice is hereby given of a proposed administrative... Hazardous Substance Superfund and additional payments when the Site is sold. The settlement includes...

  2. 78 FR 77673 - Proposed CERCLA Administrative Cost Recovery Settlement; Cadie Auto Salvage Site, Belvidere...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Cadie Auto Salvage Site, Belvidere, Boone... Act, as amended (``CERCLA''), notice is hereby given of a proposed administrative settlement for... not to sue the Settling Party pursuant to CERCLA, contribution protection for the Settling...

  3. 76 FR 14659 - Proposed CERCLA AdministrativeCost Recovery” Settlement; The Goldfield Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed CERCLA Administrative ``Cost Recovery'' Settlement; The Goldfield Corporation AGENCY... (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for...

  4. 12 CFR 1408.12 - Charges for interest, administrative costs, and penalties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Charges for interest, administrative costs, and penalties. 1408.12 Section 1408.12 Banks and Banking FARM CREDIT SYSTEM INSURANCE CORPORATION COLLECTION OF CLAIMS OWED THE UNITED STATES Administrative Collection of Claims § 1408.12 Charges for...

  5. 20 CFR 641.856 - What functions and activities constitute administrative costs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false What functions and activities constitute administrative costs? 641.856 Section 641.856 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM...

  6. 20 CFR 641.856 - What functions and activities constitute administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false What functions and activities constitute administrative costs? 641.856 Section 641.856 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM...

  7. 20 CFR 668.820 - What rules apply to administrative costs under the INA program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false What rules apply to administrative costs under the INA program? 668.820 Section 668.820 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN PROGRAMS UNDER TITLE I OF...

  8. 20 CFR 668.820 - What rules apply to administrative costs under the INA program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false What rules apply to administrative costs under the INA program? 668.820 Section 668.820 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN PROGRAMS UNDER TITLE I OF...

  9. 20 CFR 668.820 - What rules apply to administrative costs under the INA program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false What rules apply to administrative costs under the INA program? 668.820 Section 668.820 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) INDIAN AND NATIVE AMERICAN PROGRAMS UNDER TITLE I OF...

  10. No Child Left Behind and Administrative Costs: A Resource Dependence Study of Local School Districts

    ERIC Educational Resources Information Center

    Neely, Stephen R.

    2015-01-01

    This study considers the impact of federal funding on the administrative expenditures of local school districts since the passage of the No-Child-Left-Behind (NCLB) Act of 2001. Under NCLB, federal education funds were made contingent upon a variety of accountability and reporting standards, creating new administrative costs and challenges for…

  11. Innovative Feed-In Tariff Designs that Limit Policy Costs

    SciTech Connect

    Kreycik, Claire; Couture, Toby D.; Cory, Karlynn S.

    2011-06-01

    Feed-in tariffs (FITs) are the most prevalent policy used globally to reduce development risks, cut financing costs, and grow the renewable energy industry. However, concerns over escalating costs in jurisdictions with FIT policies have led to increased attention on cost control. Using case studies and market-focused analysis, this report from the National Renewable Energy Laboratory (NREL) examines strengths and weaknesses of three cost-containment tools: (1) caps, (2) payment level adjustment mechanisms, and (3) auction-based designs. The report provides useful insights on containing costs for policymakers and regulators in the United States and other areas where FIT policies are in development.

  12. 42 CFR 447.78 - Aggregate limits on alternative premiums and cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Aggregate limits on alternative premiums and cost... Provisions Alternative Premiums and Cost Sharing Under Section 1916a § 447.78 Aggregate limits on alternative premiums and cost sharing. (a) The total aggregate amount of premiums and cost sharing imposed...

  13. 76 FR 69733 - Proposed CERCLA Administrative Cost Recovery Settlement; Tracy Lead Battery Site, Tracy, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Tracy Lead Battery Site, Tracy, MN AGENCY... of past response costs concerning the Tracy Lead Battery Site in Tracy, Minnesota with the following.... Comments should reference the Tracy Lead Battery Site and EPA Docket No. CERCLA-05-2012-0001 and should...

  14. 75 FR 3236 - Federal Acquisition Regulation; Submission for OMB Review; Cost Accounting Standards Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... and the provision at 52.230-5 include pertinent rules and regulations related to the Cost Accounting... Regulation; Submission for OMB Review; Cost Accounting Standards Administration AGENCIES: Department of...-0129). SUMMARY: Under the provisions of the Paperwork Reduction Act of 1995 (44 U.S.C. Chapter 35),...

  15. 48 CFR 1422.1003-4 - Administrative limitations, variations, tolerances and exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administrative limitations, variations, tolerances and exemptions. 1422.1003-4 Section 1422.1003-4 Federal Acquisition Regulations System... Service Contract Act of 1965, as Amended 1422.1003-4 Administrative limitations, variations,...

  16. Alpine scree plants benefit from cryptic coloration with limited cost.

    PubMed

    Niu, Yang; Sun, Hang

    2014-01-01

    Like animals, plants are attacked by enemies (herbivores) that forage using visual cues; however, the defensive coloration type known as cryptic coloration was rarely reported in plants. For most autotrophic plants, because photosynthesis relies on the presence of chlorophyll, a green leaf appearance is standard. However, if having leaves that are not green is more beneficial than costly, such coloration may evolve under certain conditions. Taking advantage of the leaf color dimorphism of Corydalis benecincta, we showed that the cryptically colored leaves confer a clear benefit without obvious cost in natural populations. Based on this study, we try to provide a framework on which to base a cost-benefit analysis to investigate the evolution of cryptic leaf coloration in plants.

  17. 48 CFR 42.707 - Cost-sharing rates and limitations on indirect cost rates.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ceiling may be incorporated into the contract for prospective application. For cost sharing under research... contractor— (i) Is a new or recently reorganized company, and there is no past or recent record of incurred indirect costs; (ii) Has a recent record of a rapidly increasing indirect cost rate due to a...

  18. 14 CFR 406.109 - Administrative law judges-powers and limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Administrative law judges-powers and limitations. 406.109 Section 406.109 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.109 Administrative law...

  19. 14 CFR 406.109 - Administrative law judges-powers and limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Administrative law judges-powers and limitations. 406.109 Section 406.109 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.109 Administrative law...

  20. 14 CFR 406.109 - Administrative law judges-powers and limitations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Administrative law judges-powers and limitations. 406.109 Section 406.109 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.109 Administrative law...

  1. 14 CFR 406.109 - Administrative law judges-powers and limitations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Administrative law judges-powers and limitations. 406.109 Section 406.109 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.109 Administrative law...

  2. 14 CFR 406.109 - Administrative law judges-powers and limitations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Administrative law judges-powers and limitations. 406.109 Section 406.109 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.109 Administrative law...

  3. Impacts on irrigated agriculture of changes in electricity costs resulting from Western Area Power Administration`s power marketing alternatives

    SciTech Connect

    Edwards, B.K.; Flaim, S.J.; Howitt, R.E.; Palmer, S.C.

    1995-03-01

    Irrigation is a major factor in the growth of US agricultural productivity, especially in western states, which account for more than 85% of the nation`s irrigated acreage. In some of these states, almost all cropland is irrigated, and nearly 50% of the irrigation is done with electrically powered pumps. Therefore, even small increases in the cost of electricity could have a disproportionate impact on irrigated agriculture. This technical memorandum examines the impacts that could result from proposed changes in the power marketing programs of the Western Area Power Administration`s Salt Lake City Area Office. The changes could increase the cost of power to all Western customers, including rural municipalities and irrigation districts that rely on inexpensive federal power to pump water. The impacts are assessed by translating changes in Western`s wholesale power rate into changes in the cost of pumping water as an input for agricultural production. Farmers can adapt to higher electricity prices in many ways, such as (1) using different pumping fuels, (2) adding workers and increasing management to irrigate more efficiently, and (3) growing more drought-tolerant crops. This study projects several responses, including using less groundwater and planting fewer waterintensive crops. The study finds that when dependence on Western`s power is high, the cost of power can have a major effect on energy use, agricultural practices, and the distribution of planted acreage. The biggest percentage changes in farm income would occur (1) in Nevada and Utah (however, all projected changes are less than 2% of the baseline) and (2) under the marketing alternatives that represent the lowest capacity and energy offer considered in Western`s Electric Power Marketing Environmental Impact Statement. The aggregate impact on farm incomes and the value of total farm production would be much smaller than that suggested by the changes in water use and planted acreage.

  4. 34 CFR 609.41 - What are allowable costs and what are the limitations on allowable costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What are allowable costs and what are the limitations on allowable costs? 609.41 Section 609.41 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION STRENGTHENING...

  5. 34 CFR 608.40 - What are allowable costs and what are the limitations on allowable costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What are allowable costs and what are the limitations on allowable costs? 608.40 Section 608.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION STRENGTHENING...

  6. 45 CFR 800.106 - Cost-sharing limits, advance payments of premium tax credits, and cost-sharing reductions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Cost-sharing limits, advance payments of premium tax credits, and cost-sharing reductions. 800.106 Section 800.106 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF PERSONNEL MANAGEMENT MULTI-STATE PLAN PROGRAM...

  7. 45 CFR 800.106 - Cost-sharing limits, advance payments of premium tax credits, and cost-sharing reductions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cost-sharing limits, advance payments of premium tax credits, and cost-sharing reductions. 800.106 Section 800.106 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF PERSONNEL MANAGEMENT MULTI-STATE PLAN PROGRAM...

  8. 24 CFR 570.610 - Uniform administrative requirements and cost principles.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Uniform administrative requirements and cost principles. 570.610 Section 570.610 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING...

  9. 76 FR 79678 - Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San... Hollywood Operable Unit of the San Fernando Valley Area 1 Superfund Site, located in the vicinity of Los... to the North Hollywood Operable Unit Special Account within the Hazardous Substance Superfund....

  10. 76 FR 77528 - Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San... Hollywood Operable Unit of the San Fernando Valley Area 1 Superfund Site, located in the vicinity of Los... to the North Hollywood Operable Unit Special Account within the Hazardous Substance Superfund....

  11. 76 FR 64943 - Proposed Cercla Administrative Cost Recovery Settlement; ACM Smelter and Refinery Site, Located...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... AGENCY Proposed Cercla Administrative Cost Recovery Settlement; ACM Smelter and Refinery Site, Located in..., Compensation, and Liability Act, as amended (CERCLA), 42 U.S.C. 9622(i), notice is hereby given of a proposed... portions of Operable Unit 1 of the Site, and to pay $1,050,000.00 to the Hazardous Substance Superfund...

  12. 75 FR 10481 - Proposed CERCLA Administrative Cost Recovery Settlement: Sherwood Motors, Inc.; West Site/Hows...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement: Sherwood Motors, Inc.; West Site/Hows Corner Superfund Site, Plymouth, ME AGENCY: U.S. Environmental Protection Agency. ACTION: Notice; request... Response, Compensation and Liability Act (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of...

  13. 76 FR 71342 - Proposed CERCLA Administrative Cost Recovery Settlement; River Forest Dry Cleaners Site, River...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; River Forest Dry Cleaners Site, River..., Compensation, and Liability Act, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a... of receipt of notice by the Settling Party that EPA has signed the CERCLA 122(h), 42 U.S.C....

  14. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Administration of the Cost-Sharing Plan. 24.241 Section 24.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the...

  15. 75 FR 36388 - Proposed Administrative Cost Recovery Settlement Under Section 122(h) of the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Environmental Response Compensation and Liability Act, as Amended, 42 U.S.C. 9622(h), Doe Run Resources... administrative settlement with Doe Run Resources Corporation (Doe Run), for recovery of past response costs concerning the response actions taken by Doe Run to address lead contamination associated with a...

  16. 34 CFR 363.51 - What are the allowable administrative costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What are the allowable administrative costs? 363.51 Section 363.51 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION THE STATE SUPPORTED...

  17. 77 FR 22785 - Proposed CERCLA Administrative Cost Recovery Settlement; Estate of Benjamin C. Schilberg...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement; Estate of Benjamin C. Schilberg... the Comprehensive Environmental Response Compensation, and Liability Act, as amended (``CERCLA''), 42... settling party pursuant to Section 107(a) of CERCLA, 42 U.S.C. 9607(a). For thirty (30) days following...

  18. 77 FR 19425 - Prescription Drugs Not Administered During Treatment; Update to Administrative Cost for Calendar...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... AFFAIRS Prescription Drugs Not Administered During Treatment; Update to Administrative Cost for Calendar... purposes of calculating VA's charges for prescription drugs that were not administered during treatment but... administered during treatment for: (1) A nonservice-connected disability for which the veteran is entitled...

  19. 78 FR 22451 - Cost Recovery for Permit Processing, Administration, and Enforcement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Parts 701, 736, 737, 738, and 750 RIN 1029-AC65 Cost Recovery for Permit Processing, Administration, and Enforcement Correction In proposed...

  20. 17 CFR 143.3 - Interest, penalty charges, and administrative costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Interest, penalty charges, and administrative costs. 143.3 Section 143.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COLLECTION OF CLAIMS OWED THE UNITED STATES ARISING FROM ACTIVITIES UNDER THE COMMISSION'S...

  1. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Administration of the Cost-Sharing Plan. 24.241 Section 24.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the...

  2. 47 CFR 24.241 - Administration of the Cost-Sharing Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Administration of the Cost-Sharing Plan. 24.241 Section 24.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PERSONAL COMMUNICATIONS SERVICES Broadband PCS Policies Governing Microwave Relocation from the...

  3. 78 FR 13675 - Federal Acquisition Regulation; Submission for OMB Review; Cost Accounting Standards Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... accounting practice change, the total potential impact of the change on contracts containing a CAS provision... Regulation; Submission for OMB Review; Cost Accounting Standards Administration AGENCY: Department of Defense...: Under the provisions of the Paperwork Reduction Act, the Regulatory Secretariat will be submitting...

  4. The Program Administrator Cost of Saved Energy for Utility Customer-Funded Energy Efficiency Programs

    SciTech Connect

    Billingsley, Megan A.; Hoffman, Ian M.; Stuart, Elizabeth; Schiller, Steven R.; Goldman, Charles A.; LaCommare, Kristina

    2014-03-19

    End-use energy efficiency is increasingly being relied upon as a resource for meeting electricity and natural gas utility system needs within the United States. There is a direct connection between the maturation of energy efficiency as a resource and the need for consistent, high-quality data and reporting of efficiency program costs and impacts. To support this effort, LBNL initiated the Cost of Saved Energy Project (CSE Project) and created a Demand-Side Management (DSM) Program Impacts Database to provide a resource for policy makers, regulators, and the efficiency industry as a whole. This study is the first technical report of the LBNL CSE Project and provides an overview of the project scope, approach, and initial findings, including: • Providing a proof of concept that the program-level cost and savings data can be collected, organized, and analyzed in a systematic fashion; • Presenting initial program, sector, and portfolio level results for the program administrator CSE for a recent time period (2009-2011); and • Encouraging state and regional entities to establish common reporting definitions and formats that would make the collection and comparison of CSE data more reliable. The LBNL DSM Program Impacts Database includes the program results reported to state regulators by more than 100 program administrators in 31 states, primarily for the years 2009–2011. In total, we have compiled cost and energy savings data on more than 1,700 programs over one or more program-years for a total of more than 4,000 program-years’ worth of data, providing a rich dataset for analyses. We use the information to report costs-per-unit of electricity and natural gas savings for utility customer-funded, end-use energy efficiency programs. The program administrator CSE values are presented at national, state, and regional levels by market sector (e.g., commercial, industrial, residential) and by program type (e.g., residential whole home programs, commercial new

  5. Cost saving and safety issues in the Billings Area of the Western Area Power Administration

    SciTech Connect

    Not Available

    1980-09-11

    This report concerns possible cost savings that would result from a proposed transfer of power-dispatch functions from Fort Peck, Montana to Jamestown, North Dakota, in the Billings Area of the Western Area Power Administration (the Power Administration) and related issues concerning the reliability of service and the safety of personnel in the operation of the Billings Area of the Power Administration. Each of the three requests to the Inspector General (IG) raised the following questions: (1) Will the proposed transfer of the power dispatch function result in cost savings. (2) Will any detriment to the Power Administration's service to its Montana customers result from the transfer. (3) Will the safety of people who work on the electrical power systems in Montana be jeopardized by the transfer. IG recommended: (a) that the Power Administration reevaluate the adequacy of the plan to staff the Jamestown facility with a sufficient number of experienced power dispatchers familiar with the Montana power distribution system, and (b) that the Power Administration strictly enforce its published procedures for training, testing, and certifying operations and maintenance personnel.

  6. Cost of Radiotherapy Versus NSAID Administration for Prevention of Heterotopic Ossification After Total Hip Arthroplasty

    SciTech Connect

    Strauss, Jonathan B. Chen, Sea S.; Shah, Anand P.; Coon, Alan B.; Dickler, Adam

    2008-08-01

    Purpose: Heterotopic ossification (HO), or abnormal bone formation, is a common sequela of total hip arthroplasty. This abnormal bone can impair joint function and must be surgically removed to restore mobility. HO can be prevented by postoperative nonsteroidal anti-inflammatory drug (NSAID) use or radiotherapy (RT). NSAIDs are associated with multiple toxicities, including gastrointestinal bleeding. Although RT has been shown to be more efficacious than NSAIDs at preventing HO, its cost-effectiveness has been questioned. Methods and Materials: We performed an analysis of the cost of postoperative RT to the hip compared with NSAID administration, taking into account the costs of surgery for HO formation, treatment-induced morbidity, and productivity loss from missed work. The costs of RT, surgical revision, and treatment of gastrointestinal bleeding were estimated using the 2007 Medicare Fee Schedule and inpatient diagnosis-related group codes. The cost of lost wages was estimated using the 2006 median salary data from the U.S. Census Bureau. Results: The cost of administering RT was estimated at $899 vs. $20 for NSAID use. After accounting for the additional costs associated with revision total hip arthroplasty and gastrointestinal bleeding, the corresponding estimated costs were $1,208 vs. $930. Conclusion: If the costs associated with treatment failure and treatment-induced morbidity are considered, the cost of NSAIDs approaches that of RT. Other NSAID morbidities and quality-of-life differences that are difficult to quantify add to the cost of NSAIDs. These considerations have led us to recommend RT as the preferred modality for use in prophylaxis against HO after total hip arthroplasty, even when the cost is considered.

  7. Health Care Costs for Patients With Chronic Spinal Cord Injury in the Veterans Health Administration

    PubMed Central

    French, Dustin D; Campbell, Robert R; Sabharwal, Sunil; Nelson, Audrey L; Palacios, Polly A; Gavin-Dreschnack, Deborah

    2007-01-01

    Background/Objective: Recurring annual costs of caring for patients with chronic spinal cord injury (SCI) is a large economic burden on health care systems, but information on costs of SCI care beyond the acute and initial postacute phase is sparse. The objective of this study was to establish a frame of reference and estimate of the annual direct medical costs associated with health care for a sample of patients with chronic SCI (ie, >2 years after injury). Methods: Patients were recruited from 3 Veterans Health Administration (VHA) SCI facilities; baseline patient information was cross-referenced to the Decision Support System (DSS) National Data Extracts (NDE) to obtain patient-specific health care costs in VHA. Descriptive statistical analysis of annual DSS-NDE cost of patients with SCI (N = 675) for fiscal year (FY) 2005 by level and completeness of injury was conducted. Results: Total (inpatient and outpatient) annual (FY 2005) direct medical costs for 675 patients with SCI exceeded $14.47 million or $21,450 per patient. Average annual total costs varied from $28,334 for cervical complete SCI to $16,792 for thoracic incomplete SCI. Two hundred thirty-three of the 675 patients with SCI who were hospitalized over the study period accounted for a total of 378 hospital discharges, costing in excess of $7.19 million. This approximated a cost of outpatient care received of $7.28 million for our entire sample. Conclusions: The comprehensive nature of health care delivery and related cost capture for people with chronic SCI in the VHA provided us the opportunity to accurately determine health care costs for this population. Future SCI postacute care cost analyses should consider case-mix adjusting patients at high risk for rehospitalization. PMID:18092564

  8. 40 CFR 35.925-18 - Limitation upon project costs incurred prior to award.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... project costs in the following cases: (1) Step 1 work begun after the date of approval by the Regional Administrator of a plan of study, if the State requests and the Regional Administrator has reserved funds for..., 1975, in accordance with an approved plan of study or an approved facilities plan, as appropriate,...

  9. 76 FR 8293 - Natural Gas Pipelines; Project Cost and Annual Limits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... Energy Regulatory Commission 18 CFR Part 157 Natural Gas Pipelines; Project Cost and Annual Limits...) computes and publishes the project cost and annual limits for natural gas pipelines blanket construction... practice and procedure, Natural Gas, Reporting and recordkeeping requirements. Jeff C. Wright,...

  10. 77 FR 8724 - Natural Gas Pipelines; Project Cost and Annual Limits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... Energy Regulatory Commission 18 CFR Part 157 Natural Gas Pipelines; Project Cost and Annual Limits... (OEP) computes and publishes the project cost and annual limits for natural gas pipelines blanket..., Natural gas, Reporting and recordkeeping requirements. Jeff C. Wright, Director, Office of Energy...

  11. Costs of Integrated Mass Drug Administration for Neglected Tropical Diseases in Haiti

    PubMed Central

    Goldman, Ann S.; Brady, Molly A.; Direny, Abdel; Desir, Luccene; Oscard, Roland; Vely, Jean-Francois; Linehan, Mary; Baker, Margaret

    2011-01-01

    We conducted a cost analysis of Haiti's Ministry of Public Health and Population neglected tropical disease program, Projet des Maladies Tropicales Negligées and collected data for 9 of 55 communes participating in the May 2008–April 2009 mass drug administration (MDA). The Projet des Maladies Tropicales Negligées Program partnered with IMA World Health and Hôpital Ste. Croix to implement MDA for treatment of lymphatic filariasis and soil-transmitted helminthiasis by using once a year treatment with albendazole and diethylcarbamazine in a population of approximately 8 million persons. Methods included analyzing partner financial records and conducting retrospective surveys of personnel. In the nine communes, 633,261 persons were treated at a cost of U.S. $0.64 per person, which included the cost of donated drugs, and at a cost of U.S. $0.42 per person treated, when excluding donated drug costs. The MDA for lymphatic filariasis in Haiti began in 2000, with the treatment of 105,750 persons at a cost per person of U.S. $2.23. The decrease in cost per person treated is the result of cumulative implementation experience and economies of scale. PMID:22049035

  12. 34 CFR 656.30 - What are allowable costs and limitations on allowable costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... costs? 656.30 Section 656.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR...; and (8) Summer institutes in the United States or abroad designed to provide language and...

  13. 34 CFR 656.30 - What are allowable costs and limitations on allowable costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... costs? 656.30 Section 656.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR...; and (8) Summer institutes in the United States or abroad designed to provide language and...

  14. 34 CFR 656.30 - What are allowable costs and limitations on allowable costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... costs? 656.30 Section 656.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR...; and (8) Summer institutes in the United States or abroad designed to provide language and...

  15. 34 CFR 656.30 - What are allowable costs and limitations on allowable costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... costs? 656.30 Section 656.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR...; and (8) Summer institutes in the United States or abroad designed to provide language and...

  16. 31 CFR 5.5 - How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury debt? 5.5 Section 5.5 Money and Finance... Debts § 5.5 How will Treasury entities add interest, penalty charges, and administrative costs to...

  17. 15 CFR 19.5 - How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce debt? 19.5 Section 19.5 Commerce and... Debts § 19.5 How will Commerce entities add interest, penalty charges, and administrative costs to...

  18. 36 CFR 1011.5 - What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false What interest, penalty charges and administrative costs will the Presidio Trust add to a debt? 1011.5 Section 1011.5 Parks... § 1011.5 What interest, penalty charges and administrative costs will the Presidio Trust add to a...

  19. 31 CFR 5.5 - How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury debt? 5.5 Section 5.5 Money and Finance... Debts § 5.5 How will Treasury entities add interest, penalty charges, and administrative costs to...

  20. 36 CFR 1011.5 - What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What interest, penalty charges and administrative costs will the Presidio Trust add to a debt? 1011.5 Section 1011.5 Parks... § 1011.5 What interest, penalty charges and administrative costs will the Presidio Trust add to a...

  1. 15 CFR 19.5 - How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce debt? 19.5 Section 19.5 Commerce and... Debts § 19.5 How will Commerce entities add interest, penalty charges, and administrative costs to...

  2. 36 CFR 1011.5 - What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What interest, penalty charges and administrative costs will the Presidio Trust add to a debt? 1011.5 Section 1011.5 Parks... § 1011.5 What interest, penalty charges and administrative costs will the Presidio Trust add to a...

  3. 36 CFR 1011.5 - What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false What interest, penalty charges and administrative costs will the Presidio Trust add to a debt? 1011.5 Section 1011.5 Parks... § 1011.5 What interest, penalty charges and administrative costs will the Presidio Trust add to a...

  4. 15 CFR 19.5 - How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce debt? 19.5 Section 19.5 Commerce and... Debts § 19.5 How will Commerce entities add interest, penalty charges, and administrative costs to...

  5. 31 CFR 5.5 - How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury debt? 5.5 Section 5.5 Money and Finance... Debts § 5.5 How will Treasury entities add interest, penalty charges, and administrative costs to...

  6. 31 CFR 5.5 - How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury debt? 5.5 Section 5.5 Money and Finance... Debts § 5.5 How will Treasury entities add interest, penalty charges, and administrative costs to...

  7. 15 CFR 19.5 - How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce debt? 19.5 Section 19.5 Commerce and... Debts § 19.5 How will Commerce entities add interest, penalty charges, and administrative costs to...

  8. 31 CFR 5.5 - How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false How will Treasury entities add interest, penalty charges, and administrative costs to a Treasury debt? 5.5 Section 5.5 Money and Finance... Debts § 5.5 How will Treasury entities add interest, penalty charges, and administrative costs to...

  9. 15 CFR 19.5 - How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false How will Commerce entities add interest, penalty charges, and administrative costs to a Commerce debt? 19.5 Section 19.5 Commerce and... Debts § 19.5 How will Commerce entities add interest, penalty charges, and administrative costs to...

  10. 36 CFR 1011.5 - What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true What interest, penalty charges and administrative costs will the Presidio Trust add to a debt? 1011.5 Section 1011.5 Parks, Forests... What interest, penalty charges and administrative costs will the Presidio Trust add to a debt?...

  11. Risk-adjusted impact of administrative costs on the distribution of terminal wealth for long-term investment.

    PubMed

    Guillén, Montserrat; Jarner, Søren Fiig; Nielsen, Jens Perch; Pérez-Marín, Ana M

    2014-01-01

    The impact of administrative costs on the distribution of terminal wealth is approximated using a simple formula applicable to many investment situations. We show that the reduction in median returns attributable to administrative fees is usually at least twice the amount of the administrative costs charged for most investment funds, when considering a risk-adjustment correction over a reasonably long-term time horizon. The example we present covers a number of standard cases and can be applied to passive investments, mutual funds, and hedge funds. Our results show investors the potential losses they face in performance due to administrative costs.

  12. 75 FR 76482 - Federal Housing Administration (FHA): FHA Maximum Loan Limits for 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Federal Housing Administration (FHA): FHA Maximum Loan Limits for 2011 AGENCY: Office of the Assistant Secretary for Housing--Federal Housing Commissioner, HUD. ACTION: Notice....

  13. 29 CFR 4.123 - Administrative limitations, variances, tolerances, and exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Administrative limitations, variances, tolerances, and exemptions. 4.123 Section 4.123 Labor Office of the Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Specific Exclusions § 4.123...

  14. Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity.

    PubMed

    Murren, C J; Auld, J R; Callahan, H; Ghalambor, C K; Handelsman, C A; Heskel, M A; Kingsolver, J G; Maclean, H J; Masel, J; Maughan, H; Pfennig, D W; Relyea, R A; Seiter, S; Snell-Rood, E; Steiner, U K; Schlichting, C D

    2015-10-01

    Phenotypic plasticity is ubiquitous and generally regarded as a key mechanism for enabling organisms to survive in the face of environmental change. Because no organism is infinitely or ideally plastic, theory suggests that there must be limits (for example, the lack of ability to produce an optimal trait) to the evolution of phenotypic plasticity, or that plasticity may have inherent significant costs. Yet numerous experimental studies have not detected widespread costs. Explicitly differentiating plasticity costs from phenotype costs, we re-evaluate fundamental questions of the limits to the evolution of plasticity and of generalists vs specialists. We advocate for the view that relaxed selection and variable selection intensities are likely more important constraints to the evolution of plasticity than the costs of plasticity. Some forms of plasticity, such as learning, may be inherently costly. In addition, we examine opportunities to offset costs of phenotypes through ontogeny, amelioration of phenotypic costs across environments, and the condition-dependent hypothesis. We propose avenues of further inquiry in the limits of plasticity using new and classic methods of ecological parameterization, phylogenetics and omics in the context of answering questions on the constraints of plasticity. Given plasticity's key role in coping with environmental change, approaches spanning the spectrum from applied to basic will greatly enrich our understanding of the evolution of plasticity and resolve our understanding of limits.

  15. 48 CFR 2152.216-71 - Fixed price with limited cost redetermination-service charge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... request, OPM will furnish, during the third quarter of the current contract year, an accounting of the... cost redetermination-service charge. 2152.216-71 Section 2152.216-71 Federal Acquisition Regulations....216-71 Fixed price with limited cost redetermination—service charge. As prescribed in...

  16. 48 CFR 2152.216-70 - Fixed price with limited cost redetermination-risk charge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... request, OPM will furnish, during the third quarter of the current contract year, an accounting of the... cost redetermination-risk charge. 2152.216-70 Section 2152.216-70 Federal Acquisition Regulations....216-70 Fixed price with limited cost redetermination—risk charge. As prescribed in...

  17. The hidden cost of low prices: limited access to new drugs in India.

    PubMed

    Berndt, Ernst R; Cockburn, Iain M

    2014-09-01

    The pricing and accessibility of patent-protected drugs in low- and middle-income countries is a contentious issue in the global context. But questions about price have little meaning if a drug is not available for purchase, and the extent to which patent policy affects when (and if) new drugs become available in these countries has largely been overlooked. We examined data on the sales of 184 drugs approved by the US Food and Drug Administration between 2000 and 2009. We found that 50 percent of those 184 drugs went on sale in India only after lags of more than five years from their first worldwide introduction. More than half of the drugs that became newly available in India during the study period were produced and sold by multiple manufacturers in the country within one year of their introduction. The presence of multiple manufacturers indicates sharp competition and weak patent protection--factors that are disincentives to manufacturers to incur the costs of gaining access to the market. We conclude that modest patent and regulatory reform could bring the faster availability of a wider range of new drugs in India with limited impact on prices--a trade-off that merits greater policy attention.

  18. Modeling the Impact and Costs of Semiannual Mass Drug Administration for Accelerated Elimination of Lymphatic Filariasis

    PubMed Central

    de Vlas, Sake J.; Fischer, Peter U.; Weil, Gary J.; Goldman, Ann S.

    2013-01-01

    The Global Program to Eliminate Lymphatic Filariasis (LF) has a target date of 2020. This program is progressing well in many countries. However, progress has been slow in some countries, and others have not yet started their mass drug administration (MDA) programs. Acceleration is needed. We studied how increasing MDA frequency from once to twice per year would affect program duration and costs by using computer simulation modeling and cost projections. We used the LYMFASIM simulation model to estimate how many annual or semiannual MDA rounds would be required to eliminate LF for Indian and West African scenarios with varied pre-control endemicity and coverage levels. Results were used to estimate total program costs assuming a target population of 100,000 eligibles, a 3% discount rate, and not counting the costs of donated drugs. A sensitivity analysis was done to investigate the robustness of these results with varied assumptions for key parameters. Model predictions suggested that semiannual MDA will require the same number of MDA rounds to achieve LF elimination as annual MDA in most scenarios. Thus semiannual MDA programs should achieve this goal in half of the time required for annual programs. Due to efficiency gains, total program costs for semiannual MDA programs are projected to be lower than those for annual MDA programs in most scenarios. A sensitivity analysis showed that this conclusion is robust. Semiannual MDA is likely to shorten the time and lower the cost required for LF elimination in countries where it can be implemented. This strategy may improve prospects for global elimination of LF by the target year 2020. PMID:23301115

  19. 77 FR 75163 - Federal Acquisition Regulation; Information Collection; Contract Funding-Limitation of Costs/Funds

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Regulation; Information Collection; Contract Funding--Limitation of Costs/Funds AGENCIES: Department of... (NASA). ACTION: Notice of request for public comments regarding an extension of an existing OMB...: Submit comments identified by Information Collection 9000- 0074, Contract Funding--Limitation of...

  20. [Cost effective planning of controlled trials with diagnostic instruments of limited reproducibility].

    PubMed

    Krummenauer, F; Förster, G

    1999-06-01

    This paper proposes a simple approach for sample size prediction in controlled diagnostic or clinical trials for group comparison when the diagnostic (imaging) instrument under consideration shows limited reliability and thus calls for taking replicate measurements on each study subject. Using a specified cost function for the overall trial, a cost optimum replication number per subject is predicted, resulting in a cost-optimum predicted group size. This approach results in remarkable cost-effectiveness, as single assessment costs based on the imaging method under consideration only present a small fraction of the overall costs of preparing study subjects for a series of measurement replications by, for example, injection of nuclear or contrast agents.

  1. 75 FR 9142 - Regulations Under I.R.C. Section 7430 Relating to Awards of Administrative Costs and Attorneys...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... Awards of Administrative Costs and Attorneys Fees; Hearing Cancellation AGENCY: Internal Revenue Service... attorneys fees under section 7430 to conform to amendments made in the Taxpayer Relief Act of 1997 and...

  2. 20 CFR 641.861 - Must SCSEP recipients provide funding for the administrative costs of sub-recipients?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Must SCSEP recipients provide funding for the administrative costs of sub-recipients? 641.861 Section 641.861 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT...

  3. 20 CFR 641.861 - Must SCSEP recipients provide funding for the administrative costs of sub-recipients?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Must SCSEP recipients provide funding for the administrative costs of sub-recipients? 641.861 Section 641.861 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT...

  4. Estimating the administrative cost of regulatory noncompliance: a pilot method for quantifying the value of prevention.

    PubMed

    Emery, R J; Charlton, M A; Mathis, J L

    2000-05-01

    Routine regulatory inspections provide a valuable independent quality assurance review of radiation protection programs that ultimately serves to improve overall program performance. But when an item of non-compliance is noted, regardless of its significance or severity the ensuing notice of violation (NOV) results in an added cost to both the permit holder and the regulatory authority. Such added costs may be tangible, in the form of added work to process and resolve the NOV, or intangible, in the form of damage to organizational reputation or worker morale. If the portion of the tangible costs incurred by a regulatory agency for issuing NOVs could be quantified, the analysis could aid in the identification of agency resources that might be dedicated to other areas such as prevention. Ideally, any prevention activities would reduce the overall number of NOVs issued without impacting the routine inspection process. In this study, the administrative costs of NOV issuance and resolution was estimated by obtaining data from the professional staff of the Texas Department of Health, Bureau of Radiation Control (TDH-BRC). Based a focus group model, the data indicate that approximately $106,000 in TDH-BRC personnel resources were expended to process and resolve the 6,800 NOVs issued in Texas during 1997 inspection activities. The study's findings imply that an incremental decrease in the number of NOVs issued would result in corresponding savings of agency resources. Suggested prevention activities that might be financed through any resource savings include the dissemination of common violation data to permit holders or training for improving correspondence with regulatory agencies. The significance of this exercise is that any savings experienced by an agency could enhance permittee compliance without impacting the routine inspection process.

  5. 23 CFR Appendix F to Part 1200 - PLANNING AND ADMINISTRATION (P&A) COSTS

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (P&A) costs are those direct and indirect costs that are attributable to the management of the... rental costs specific to the Highway Safety Agency. Program management costs are those costs attributable... salary and related costs may be programmed to P&A. If the employee works performing program...

  6. 23 CFR Appendix F to Part 1200 - Planning and Administration (P&A) Costs

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (P&A) costs are those direct and indirect costs that are attributable to the management of the... rental costs specific to the Highway Safety Agency. Program management costs are those costs attributable... salary and related costs may be programmed to P&A. If the employee works performing program...

  7. 34 CFR 658.40 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What are the limitations on allowable costs? 658.40 Section 658.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN...

  8. 38 CFR 21.258 - Cost limitations on approval of self-employment plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... approval of self-employment plans. 21.258 Section 21.258 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31 Employment Services § 21.258 Cost limitations on approval of...

  9. 34 CFR 373.22 - What are the limitations on indirect costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false What are the limitations on indirect costs? 373.22 Section 373.22 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL DEMONSTRATION PROGRAMS...

  10. 34 CFR 373.22 - What are the limitations on indirect costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true What are the limitations on indirect costs? 373.22 Section 373.22 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL DEMONSTRATION PROGRAMS...

  11. 34 CFR 373.22 - What are the limitations on indirect costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What are the limitations on indirect costs? 373.22 Section 373.22 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL DEMONSTRATION PROGRAMS...

  12. 34 CFR 373.22 - What are the limitations on indirect costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What are the limitations on indirect costs? 373.22 Section 373.22 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL DEMONSTRATION PROGRAMS...

  13. 34 CFR 373.22 - What are the limitations on indirect costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What are the limitations on indirect costs? 373.22 Section 373.22 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL DEMONSTRATION PROGRAMS...

  14. 48 CFR 3452.232-70 - Limitation of cost or funds.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Limitation of cost or funds. 3452.232-70 Section 3452.232-70 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions...

  15. 34 CFR 280.41 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false What are the limitations on allowable costs? 280.41 Section 280.41 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM What...

  16. 34 CFR 280.41 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false What are the limitations on allowable costs? 280.41 Section 280.41 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM What...

  17. 34 CFR 280.41 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false What are the limitations on allowable costs? 280.41 Section 280.41 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM What...

  18. 34 CFR 280.41 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What are the limitations on allowable costs? 280.41 Section 280.41 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM What...

  19. 34 CFR 280.41 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false What are the limitations on allowable costs? 280.41 Section 280.41 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM What...

  20. 34 CFR 658.40 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What are the limitations on allowable costs? 658.40 Section 658.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN...

  1. 34 CFR 658.40 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What are the limitations on allowable costs? 658.40 Section 658.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN...

  2. 34 CFR 658.40 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What are the limitations on allowable costs? 658.40 Section 658.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN...

  3. 34 CFR 658.40 - What are the limitations on allowable costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What are the limitations on allowable costs? 658.40 Section 658.40 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN...

  4. The Impact of Debt Limitations and Referenda Requirements on the Cost of School District Bond Issues

    ERIC Educational Resources Information Center

    Harris, Mary H.; Munley, Vincent G.

    2011-01-01

    One distinction between the markets for corporate and municipal bonds involves institutional constraints that apply to some municipal bond issues. This research focuses on how public finance institutions, in particular explicit debt limits and referenda requirements, affect the borrowing cost of individual school district bond issues. The…

  5. 42 CFR 447.206 - Cost limit for providers operated by units of government.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... section applies to payments made to health care providers that are operated by units of government as...) of the Act. (a) General rules. (1) All health care providers that are operated by units of government are limited to reimbursement not in excess of the individual health care provider's cost of...

  6. 48 CFR 1832.705-270 - NASA clauses for limitation of cost or funds.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Funding 1832.705-270 NASA clauses for limitation of cost or funds. (a) The contracting officer shall... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA clauses for... insert a clause substantially as stated at 1852.232-81, Contract Funding, in Section B of...

  7. 48 CFR 1832.705-270 - NASA clauses for limitation of cost or funds.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Funding 1832.705-270 NASA clauses for limitation of cost or funds. (a) The contracting officer shall... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA clauses for... insert a clause substantially as stated at 1852.232-81, Contract Funding, in Section B of...

  8. 48 CFR 1832.705-270 - NASA clauses for limitation of cost or funds.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Funding 1832.705-270 NASA clauses for limitation of cost or funds. (a) The contracting officer shall... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA clauses for... insert a clause substantially as stated at 1852.232-81, Contract Funding, in Section B of...

  9. 48 CFR 1832.705-270 - NASA clauses for limitation of cost or funds.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Funding 1832.705-270 NASA clauses for limitation of cost or funds. (a) The contracting officer shall... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA clauses for... insert a clause substantially as stated at 1852.232-81, Contract Funding, in Section B of...

  10. 20 CFR 641.859 - What other special rules govern the classification of costs as administrative costs or...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM Administrative Requirements § 641.859 What other special rules govern... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false What other special rules govern...

  11. 20 CFR 641.859 - What other special rules govern the classification of costs as administrative costs or...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM Administrative Requirements § 641.859 What other special rules govern... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false What other special rules govern...

  12. Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis

    PubMed Central

    Moran, Corey S.; Seto, Sai-Wang; Krishna, Smriti M.; Sharma, Surabhi; Jose, Roby J.; Biros, Erik; Wang, Yutang; Morton, Susan K.; Golledge, Jonathan

    2017-01-01

    Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA). Coagulation factor Xa (FXa) catalyses FII to thrombin (FIIa). We examined the effect of FXa/FIIa inhibition on experimental aortic aneurysm in apolipoprotein E-deficient (ApoE−/−) mice infused with angiotensin II (AngII). The concentration of FXa within the supra-renal aorta (SRA) correlated positively with SRA diameter. Parenteral administration of enoxaparin (FXa/IIa inhibitor) and fondaparinux (FXa inhibitor) over 14 days reduced to severity of aortic aneurysm and atherosclerosis in AngII-infused ApoE−/− mice. Enteral administration of the FIIa inhibitor dabigatran had no significant effect. Aortic protease-activated receptor (PAR)-2 expression increased in response to AngII infusion. Fondaparinux reduced SRA levels of FXa, FIIa, PAR-2, matrix metalloproteinase (MMP)2, Smad2/3 phosphorylation, and MOMA-2 positive cells in the mouse model. FXa stimulated Smad2/3 phosphorylation and MMP2 expression in aortic vascular smooth muscle cells (VSMC) in vitro. Expression of MMP2 in FXa-stimulated VSMC was downregulated in the presence of a PAR-2 but not a PAR-1 inhibitor. These findings suggest that FXa/FIIa inhibition limits aortic aneurysm and atherosclerosis severity due to down-regulation of vascular PAR-2-mediated Smad2/3 signalling and MMP2 expression. Inhibition of FXa/FIIa may be a potential therapy for limiting aortic aneurysm. PMID:28220880

  13. Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis.

    PubMed

    Moran, Corey S; Seto, Sai-Wang; Krishna, Smriti M; Sharma, Surabhi; Jose, Roby J; Biros, Erik; Wang, Yutang; Morton, Susan K; Golledge, Jonathan

    2017-02-21

    Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA). Coagulation factor Xa (FXa) catalyses FII to thrombin (FIIa). We examined the effect of FXa/FIIa inhibition on experimental aortic aneurysm in apolipoprotein E-deficient (ApoE(-/-)) mice infused with angiotensin II (AngII). The concentration of FXa within the supra-renal aorta (SRA) correlated positively with SRA diameter. Parenteral administration of enoxaparin (FXa/IIa inhibitor) and fondaparinux (FXa inhibitor) over 14 days reduced to severity of aortic aneurysm and atherosclerosis in AngII-infused ApoE(-/-) mice. Enteral administration of the FIIa inhibitor dabigatran had no significant effect. Aortic protease-activated receptor (PAR)-2 expression increased in response to AngII infusion. Fondaparinux reduced SRA levels of FXa, FIIa, PAR-2, matrix metalloproteinase (MMP)2, Smad2/3 phosphorylation, and MOMA-2 positive cells in the mouse model. FXa stimulated Smad2/3 phosphorylation and MMP2 expression in aortic vascular smooth muscle cells (VSMC) in vitro. Expression of MMP2 in FXa-stimulated VSMC was downregulated in the presence of a PAR-2 but not a PAR-1 inhibitor. These findings suggest that FXa/FIIa inhibition limits aortic aneurysm and atherosclerosis severity due to down-regulation of vascular PAR-2-mediated Smad2/3 signalling and MMP2 expression. Inhibition of FXa/FIIa may be a potential therapy for limiting aortic aneurysm.

  14. Cost-effectiveness of triple drug administration (TDA) with praziquantel, ivermectin and albendazole for the prevention of neglected tropical diseases in Nigeria.

    PubMed

    Evans, D; McFarland, D; Adamani, W; Eigege, A; Miri, E; Schulz, J; Pede, E; Umbugadu, C; Ogbu-Pearse, P; Richards, F O

    2011-12-01

    Onchocerciasis, lymphatic filariasis (LF), schistosomiasis and soil transmitted, helminthiasis (STH) are all co-endemic in Nigeria. Annual mass drug administration (MDA) with ivermectin (for onchocerciasis), albendazole (for STH and with ivermectin for LF) and praziquantel (for schistosomiasis) is the WHO-recommended treatment strategy for preventive chemotherapy. Separate delivery rounds for distribution of these drugs have been the usual approach to MDA. All three drugs, however, have now been shown to be clinically and programmatically safe for co-administration with what has come to be known as triple drug administration (TDA). We examined the cost savings of converting from separate delivery rounds to TDA in two states in Nigeria. In 2008, eight local government areas received a single round of ivermectin with albendazole followed at least 1 week later by a single round of praziquantel to school-aged children. The following year, a single round was administered with TDA. The number of treated individuals was essentially unchanged during both years (1,301,864 in 2008 and 1,297,509 in 2009) and no change in adverse events was reported. The total programmatic costs for the MDA, not including drug and overhead costs, reduced by 41% from $123,624 to $72,870. Cost savings were limited in larger populations due to economies of scale. TDA is recommended for mature MDA.

  15. Medicare program; reissuance of the wage index in the 1981 schedule of limits on hospital per diem inpatient general routine operating costs--HCFA. Proposed notice.

    PubMed

    1984-02-17

    We are reissuing for public comment the change in the types of data that were used to calculate the wage index that was contained in the schedules of limits on hospital per diem inpatient general routine operating costs reimbursable under Medicare that were applicable to cost reporting periods beginning on or after July 1, 1981 and for cost reporting periods ending after September 30, 1981. The cost limits for cost reporting periods beginning on or after October 1, 1982 are governed by the notice published in the Federal Register on September 30, 1982 (47 FR 43296) and August 30, 1983 (48 FR 39426) and are not affected by this reissuance. The wage index was originally issued as part of the schedule of limits published on June 30, 1981 (46 FR 33637) and September 30, 1981 (46 FR 48010) and is being reissued as the result of the April 29, 1983 decision of the United States District Court for the District of Columbia in the case of District of Columbia Hospital Association, et al. v Heckler, et al. (No. 82-2520 DDC). The District Court held that the 1981 schedule of hospital cost limits was invalid for failure to comply with the Administrative Procedure Act insofar as the schedule incorporated or was formulated by using a wage index that was calculated by excluding Federal government hospital wage data.

  16. 13 CFR 142.34 - Are there any limitations on the right to appeal to the Administrator?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Are there any limitations on the right to appeal to the Administrator? 142.34 Section 142.34 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Decisions and Appeals § 142.34...

  17. Medicare program; schedule of limits on home health agency costs per visit for cost reporting periods beginning on or after July 1, 1991--HCFA. Notice with comment period.

    PubMed

    1991-12-09

    This notice sets forth a revised schedule of limits on home health agency costs that may be paid under the Medicare program. This revised schedule of limits applies to cost reporting periods beginning on or after July 1, 1991. As required by section 4207(d) of the Omnibus Budget Reconciliation Act of 1990 (Pub. L. 101-508), this revised schedule of limits incorporates a blended hospital wage index.

  18. 77 FR 46433 - Proposed CERCLA Administrative Cost Recovery Settlements for the Buckbee-Mears Co. Superfund Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlements for the Buckbee-Mears Co. Superfund Site.... Superfund Site located in Cortland, New York, Cortland County, EPA Region II Docket No.'s CERCLA-02-2012..., Compensation, and Liability Act of 1980, as amended (``CERCLA''), notice is hereby given of two...

  19. 77 FR 58989 - Proposed CERCLA Administrative Cost Recovery Settlement for the Buckbee-Mears Co. Superfund Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... AGENCY Proposed CERCLA Administrative Cost Recovery Settlement for the Buckbee-Mears Co. Superfund Site... Response, Compensation, and Liability Act of 1980, as amended (``CERCLA''), notice is hereby given of a.... Superfund Site located in Cortland, Cortland County, New York, (the ``Site'') with the State Bank of...

  20. 41 CFR 301-74.13 - May we include conference administrative costs in an employee's per diem allowance payment for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... conference administrative costs in an employee's per diem allowance payment for attendance at a conference? 301-74.13 Section 301-74.13 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 74-CONFERENCE PLANNING...

  1. 41 CFR 301-74.8 - May we include conference administrative costs in an employee's per diem allowance payment for...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... conference administrative costs in an employee's per diem allowance payment for attendance at a conference? 301-74.8 Section 301-74.8 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 74-CONFERENCE PLANNING...

  2. 41 CFR 301-74.13 - May we include conference administrative costs in an employee's per diem allowance payment for...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... conference administrative costs in an employee's per diem allowance payment for attendance at a conference? 301-74.13 Section 301-74.13 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 74-CONFERENCE PLANNING...

  3. 41 CFR 301-74.13 - May we include conference administrative costs in an employee's per diem allowance payment for...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true May we include conference administrative costs in an employee's per diem allowance payment for attendance at a conference? 301-74.13 Section 301-74.13 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY...

  4. 41 CFR 301-74.13 - May we include conference administrative costs in an employee's per diem allowance payment for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... conference administrative costs in an employee's per diem allowance payment for attendance at a conference? 301-74.13 Section 301-74.13 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 74-CONFERENCE PLANNING...

  5. The Cost of Antibiotic Mass Drug Administration for Trachoma Control in a Remote Area of South Sudan

    PubMed Central

    Kolaczinski, Jan H.; Robinson, Emily; Finn, Timothy P.

    2011-01-01

    Background Mass drug administration (MDA) of antibiotics is a key component of the so-called “SAFE” strategy for trachoma control, while MDA of anthelminthics provides the cornerstone for control of a number of other neglected tropical diseases (NTDs). Simultaneous delivery of two or more of these drugs, renowned as “integrated NTD control,” is being promoted to reduce costs and expand intervention coverage. A cost analysis was conducted alongside an MDA campaign in a remote trachoma endemic area, to inform budgeting for NTD control in South Sudan. Methods and Findings A first round of antibiotic MDA was conducted in the highly trachoma endemic county of Mayom, Unity state, from June to August 2010. A core team of seven staff delivered the intervention, including recruitment and training of 44 supervisors and 542 community drug distributors. Using an ingredients approach, financial and economic costs were captured from the provider perspective in a detailed costing database. Overall, 123,760 individuals were treated for trachoma, resulting in an estimated treatment coverage of 94%. The economic cost per person treated was USD 1.53, excluding the cost of the antibiotic azithromycin. Ninety four per cent of the delivery costs were recurrent costs, with personnel and travel/transport costs taking up the largest share. Conclusions In a remote setting and for the initial round, MDA of antibiotics was considerably more expensive than USD 0.5 per person treated, an estimate frequently quoted to advocate for integrated NTD control. Drug delivery costs in South Sudan are unlikely to decrease substantially during subsequent MDA rounds, as the major cost drivers were recurrent costs. MDA campaigns for delivery of one or more drugs in South Sudan should thus be budgeted at around USD 1.5 per person treated, at least until further costing data for delivery of other NTD drugs, singly or in combination, are available. PMID:22022632

  6. Medicare program; schedule of limits on home health agency costs per visit for cost reporting periods beginning on or after July 1, 1989--HCFA. Final notice.

    PubMed

    1991-03-28

    This final notice sets forth a revised schedule of limits on home health agency costs that may be paid under the Medicare program. This revised schedule of limits applies to cost reporting periods beginning on or after July 1, 1989 and before July 1, 1991. As required by section 6222 of the Omnibus Budget Reconciliation Act of 1989 (Pub. L. 101-239), the revised schedule of limits incorporates the hospital wage index in effect for cost reporting periods beginning prior to July 1, 1989.

  7. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... certain confidential business information under administrative protective order. In an investigation...

  8. 76 FR 47238 - Ninth Administrative Review of Honey From the People's Republic of China: Extension of Time Limit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ...: Extension of Time Limit for the Preliminary Results AGENCY: Import Administration, International Trade... Honey Producers Association and the Sioux Honey Association. ] Extension of Time Limits for the... the statutory time period is not practicable. The Department requires more time to gather and...

  9. 19 CFR 207.7 - Limited disclosure of certain business proprietary information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... information under administrative protective order. 207.7 Section 207.7 Customs Duties UNITED STATES... administrative protective order. (a)(1) Disclosure. Upon receipt of a timely application filed by an authorized... authorized applicant under an administrative protective order described in paragraph (b) of this section....

  10. 19 CFR 207.7 - Limited disclosure of certain business proprietary information under administrative protective...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... information under administrative protective order. 207.7 Section 207.7 Customs Duties UNITED STATES... administrative protective order. (a)(1) Disclosure. Upon receipt of a timely application filed by an authorized... authorized applicant under an administrative protective order described in paragraph (b) of this section....

  11. 19 CFR 207.7 - Limited disclosure of certain business proprietary information under administrative protective...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... information under administrative protective order. 207.7 Section 207.7 Customs Duties UNITED STATES... administrative protective order. (a)(1) Disclosure. Upon receipt of a timely application filed by an authorized... authorized applicant under an administrative protective order described in paragraph (b) of this section....

  12. 10 CFR 719.32 - For what costs is the contractor, or Department retained counsel, limited to reimbursement of...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false For what costs is the contractor, or Department retained counsel, limited to reimbursement of actual costs only? 719.32 Section 719.32 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Reimbursement of Costs Subject to This Part § 719.32 For what...

  13. 10 CFR 719.32 - For what costs is the contractor, or Department retained counsel, limited to reimbursement of...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false For what costs is the contractor, or Department retained counsel, limited to reimbursement of actual costs only? 719.32 Section 719.32 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Reimbursement of Costs Subject to This Part § 719.32 For what...

  14. 10 CFR 719.32 - For what costs is the contractor, or Department retained counsel, limited to reimbursement of...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false For what costs is the contractor, or Department retained counsel, limited to reimbursement of actual costs only? 719.32 Section 719.32 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Reimbursement of Costs Subject to This Part § 719.32 For what...

  15. Delivering pediatric HIV care in resource-limited settings: cost considerations in an expanded response.

    PubMed

    Tolle, Michael A; Phelps, B Ryan; Desmond, Chris; Sugandhi, Nandita; Omeogu, Chinyere; Jamieson, David; Ahmed, Saeed; Reuben, Elan; Muhe, Lulu; Kellerman, Scott E

    2013-11-01

    If children are to be protected from HIV, the expansion of PMTCT programs must be complemented by increased provision of paediatric treatment. This is expensive, yet there are humanitarian, equity and children's rights arguments to justify the prioritization of treating HIV-infected children. In the context of limited budgets, inefficiencies cost lives, either through lower coverage or less effective services. With the goal of informing the design and expansion of efficient paediatric treatment programs able to utilize to greatest effect the available resources allocated to the treatment of HIV-infected children, this article reviews what is known about cost drivers in paediatric HIV interventions, and makes suggestions for improving efficiency in paediatric HIV programming. High-impact interventions known to deliver disproportional returns on investment are highlighted and targeted for immediate scale-up. Progress will carry a cost - increased funding, as well as additional data on intervention costs and outcomes, will be required if universal access of HIV-infected children to treatment is to be achieved and sustained.

  16. Subcutaneous vs intravenous administration of immunoglobulin in chronic inflammatory demyelinating polyneuropathy: an Italian cost-minimization analysis.

    PubMed

    Lazzaro, Carlo; Lopiano, Leonardo; Cocito, Dario

    2014-07-01

    Prior researches have suggested that home-based subcutaneous immunoglobulin (SCIG) is equally effective and can be less expensive than hospital-based intravenous immunoglobulin (IVIG) in treating chronic inflammatory demyelinating polyneuropathy (CIDP) patients. This economic evaluation aims at comparing costs of SCIG vs IVIG for CIDP patients in Italy. A 1-year model-based cost-minimization analysis basically populated via neurologists' opinion was undertaken from a societal perspective. Health care resources included immunoglobulin; drugs for premedication and complications (rash, headache, and hypertension) management; time of various health care professionals; pump for SCIG self-administration; infusion disposables. Non-health care resources encompassed transport and parking; losses of working and leisure time for patients and caregivers. Unit or yearly costs for resources valuation were mainly obtained from published sources. Costs were expressed in Euro () 2013. An extensive one-way sensitivity analysis (OWSA) and a scenario SA tested the robustness of the base case findings. Overall costs per patient amount to 49,534.75 (SCIG) and 50,895.73 (IVIG); saving in favour of SCIG reaches 1360.98. For both SCIG and IVIG, the cost driver was immunoglobulin (94.06 vs 86.06 % of the overall costs, respectively). Sensitivity analyses confirmed the consistency of the baseline results. SCIG may be a cost-saving therapy for Italian CIDP patients.

  17. Regulatory and cost barriers are likely to limit biosimilar development and expected savings in the near future.

    PubMed

    Grabowski, Henry G; Guha, Rahul; Salgado, Maria

    2014-06-01

    In March 2010 Congress established an abbreviated Food and Drug Administration approval pathway for biosimilars-drugs that are very similar but not identical to a reference biological product and cost less. Because bringing biosimilars to the market currently requires large investments of money, fewer biosimilars are expected to enter the biologics market than has been the case with generic drugs entering the small-molecule drug market. Additionally, given the high regulatory hurdles to obtaining interchangeability-which would allow pharmacists to substitute a biosimilar for its reference product, subject to evolving state substitution laws-most biosimilars will likely compete as therapeutic alternatives instead of as therapeutic equivalents. In other words, biosimilars will need to compete with their reference product on the basis of quality; price; and manufacturer's reputation with physicians, insurers, and patient groups. Biosimilars also will face dynamic competition from new biologics in the same therapeutic class-including "biobetters," which offer incremental improvements on reference products, such as extended duration of action. The prospects for significant cost savings from the use of biosimilars appear to be limited for the next several years, but their use should increase over time because of both demand- and supply-side factors.

  18. Cost-appropriateness of whole body vs limited bone imaging for suspected focal sports injuries

    SciTech Connect

    Nagle, C.E.

    1986-07-01

    Bone imaging has been recognized as a useful diagnostic tool in detecting the presence of focal musculoskeletal injury when radiographs are normal. A retrospective review of bone images in a small number of amateur athletes indicates that secondary injuries were commonly detected at sites different from the site of musculoskeletal pain being evaluated for injury. While a larger study will be necessary to confirm the data, this review suggests that it is medically justified and cost-appropriate to perform imaging of the entire skeleton as opposed to imaging limited to the anatomic site of pain and suspected injury.

  19. 15 CFR 40.4 - Administrative provisions on selection of participants and funding of costs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... participants and funding of costs. (a) Within the framework of the aforementioned Memorandum of Agreement, the... including, where appropriate, each participant's education and experience, type of training desired,...

  20. 15 CFR 40.4 - Administrative provisions on selection of participants and funding of costs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... participants and funding of costs. (a) Within the framework of the aforementioned Memorandum of Agreement, the... including, where appropriate, each participant's education and experience, type of training desired,...

  1. 15 CFR 40.4 - Administrative provisions on selection of participants and funding of costs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... participants and funding of costs. (a) Within the framework of the aforementioned Memorandum of Agreement, the... including, where appropriate, each participant's education and experience, type of training desired,...

  2. 15 CFR 40.4 - Administrative provisions on selection of participants and funding of costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... participants and funding of costs. (a) Within the framework of the aforementioned Memorandum of Agreement, the... including, where appropriate, each participant's education and experience, type of training desired,...

  3. Limited applicability of cost-effectiveness and cost-benefit analyses for the optimization of radon remedial measures.

    PubMed

    Jiránek, Martin; Rovenská, Katerina

    2010-10-15

    Ways of using different decision-aiding techniques for optimizing and evaluating radon remedial measures have been studied on a large set of data obtained from the remediation of 32 houses that had an original indoor radon level above 1000 Bq/m(3). Detailed information about radon concentrations before and after remediation, type of remedial measures and installation and operation costs were used as the input parameters for a comparison of costs and for determining the efficiencies, for a cost-benefit analysis and a cost-effectiveness analysis, in order to find out whether these criteria and techniques provide sufficient and relevant information for improving and optimizing remediation. Our study confirmed that the installation costs of remediation do not depend on the original indoor radon level, but on the technical state of the building. In addition, the study reveals that the efficiency of remediation does not depend on the installation costs. Cost-benefit analysis and cost-effectiveness analysis lead to the conclusion that remedial measures reducing the indoor radon concentration from values above 1000 Bq/m(3) are always acceptable and reasonable. On the other hand, these techniques can neither help the designer to choose the proper remedial measure nor provide information resulting in improved remediation.

  4. Initial investigation into lower-cost CT for resource limited regions of the world

    NASA Astrophysics Data System (ADS)

    Dobbins, James T., III; Wells, Jered R.; Segars, W. Paul; Li, Christina M.; Kigongo, Christopher J. N.

    2010-04-01

    This paper describes an initial investigation into means for producing lower-cost CT scanners for resource limited regions of the world. In regions such as sub-Saharan Africa, intermediate level medical facilities serving millions have no CT machines, and lack the imaging resources necessary to determine whether certain patients would benefit from being transferred to a hospital in a larger city for further diagnostic workup or treatment. Low-cost CT scanners would potentially be of immense help to the healthcare system in such regions. Such scanners would not produce state-of-theart image quality, but rather would be intended primarily for triaging purposes to determine the patients who would benefit from transfer to larger hospitals. The lower-cost scanner investigated here consists of a fixed digital radiography system and a rotating patient stage. This paper describes initial experiments to determine if such a configuration is feasible. Experiments were conducted using (1) x-ray image acquisition, a physical anthropomorphic chest phantom, and a flat-panel detector system, and (2) a computer-simulated XCAT chest phantom. Both the physical phantom and simulated phantom produced excellent image quality reconstructions when the phantom was perfectly aligned during acquisition, but artifacts were noted when the phantom was displaced to simulate patient motion. An algorithm was developed to correct for motion of the phantom and demonstrated success in correcting for 5-mm motion during 360-degree acquisition of images. These experiments demonstrated feasibility for this approach, but additional work is required to determine the exact limitations produced by patient motion.

  5. Quantifying limitations in chemotherapy data in administrative health databases: implications for measuring the quality of colorectal cancer care.

    PubMed

    Urquhart, Robin; Rayson, Daniel; Porter, Geoffrey A; Grunfeld, Eva

    2011-08-01

    Reliable chemotherapy data are critical to evaluate the quality of care for patients with colorectal cancer who are treated with curative intent. In Canada, limitations in the availability and completeness of chemotherapy data exist in many administrative health databases. In this paper, we discuss these limitations and present findings from a chart review in Nova Scotia that quantifies the completeness of chemotherapy capture in existing databases. The results demonstrate that even basic information on cancer treatment in administrative databases can be insufficient to perform the types of analyses that most decision-makers require for quality-of-care measurement.

  6. 77 FR 44238 - Proposed Administrative Cost Recovery Settlement Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... amended (CERCLA), notice is hereby given of a proposed administrative settlement with The Doe Run... Mine Tailings Superfund Site in St. Francois County, Missouri. The settlement requires The Doe...

  7. 34 CFR 403.195 - What are the administrative cost requirements applicable to local recipients?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... reasonable for the proper and efficient administration of the projects, services, and activities for which... partner that receives an award under the Business-Labor-Education Partnership for Training Program may...

  8. 13 CFR 120.883 - Eligible administrative costs for 504 loans.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) CDC processing fee; (d) Borrower's out-of-pocket costs associated with 504 loan and Debenture closing...) CDC Closing Fee (see § 120.971(a)(2)) up to a maximum of $2,500; and (f) Underwriters' fee....

  9. 13 CFR 120.883 - Eligible administrative costs for 504 loans.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) CDC processing fee; (d) Borrower's out-of-pocket costs associated with 504 loan and Debenture closing...) CDC Closing Fee (see § 120.971(a)(2)) up to a maximum of $2,500; and (f) Underwriters' fee....

  10. 13 CFR 120.883 - Eligible administrative costs for 504 loans.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) CDC processing fee; (d) Borrower's out-of-pocket costs associated with 504 loan and Debenture closing...) CDC Closing Fee (see § 120.971(a)(2)) up to a maximum of $2,500; and (f) Underwriters' fee....

  11. 13 CFR 120.883 - Eligible administrative costs for 504 loans.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) CDC processing fee; (d) Borrower's out-of-pocket costs associated with 504 loan and Debenture closing...) CDC Closing Fee (see § 120.971(a)(2)) up to a maximum of $2,500; and (f) Underwriters' fee....

  12. 13 CFR 120.883 - Eligible administrative costs for 504 loans.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) CDC processing fee; (d) Borrower's out-of-pocket costs associated with 504 loan and Debenture closing...) CDC Closing Fee (see § 120.971(a)(2)) up to a maximum of $2,500; and (f) Underwriters' fee....

  13. 48 CFR 52.230-6 - Administration of Cost Accounting Standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... by the CFAO, submit on or before a date specified by the CFAO— (1) A general dollar magnitude (GDM... estimated general dollar magnitude of the cost impact), until such time as the Contractor provides...

  14. 34 CFR 226.23 - May charter schools use grant funds for administrative costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false May charter schools use grant funds for administrative... INCENTIVE PROGRAM What Conditions Must Be Met by a Grantee? § 226.23 May charter schools use grant funds for... charter school subgrantees that use grant funds for construction activities may not be reimbursed...

  15. 34 CFR 226.23 - May charter schools use grant funds for administrative costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false May charter schools use grant funds for administrative... INCENTIVE PROGRAM What Conditions Must Be Met by a Grantee? § 226.23 May charter schools use grant funds for... charter school subgrantees that use grant funds for construction activities may not be reimbursed...

  16. 34 CFR 226.23 - May charter schools use grant funds for administrative costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false May charter schools use grant funds for administrative... INCENTIVE PROGRAM What Conditions Must Be Met by a Grantee? § 226.23 May charter schools use grant funds for... charter school subgrantees that use grant funds for construction activities may not be reimbursed...

  17. 34 CFR 226.23 - May charter schools use grant funds for administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false May charter schools use grant funds for administrative... INCENTIVE PROGRAM What Conditions Must Be Met by a Grantee? § 226.23 May charter schools use grant funds for... charter school subgrantees that use grant funds for construction activities may not be reimbursed...

  18. 34 CFR 226.23 - May charter schools use grant funds for administrative costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false May charter schools use grant funds for administrative... INCENTIVE PROGRAM What Conditions Must Be Met by a Grantee? § 226.23 May charter schools use grant funds for... charter school subgrantees that use grant funds for construction activities may not be reimbursed...

  19. 15 CFR 40.4 - Administrative provisions on selection of participants and funding of costs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... statistical activities of their home country. (c) Arrangements for security clearances, insurance, orientation... PARTICIPANTS IN CENSUS PROCEDURES AND GENERAL STATISTICS § 40.4 Administrative provisions on selection of..., a program for technical training of foreign participants in censuses and statistics. The Bureau...

  20. Medicare program; schedule of limits on home health agency costs per visit--HCFA. Notice with comment period.

    PubMed

    1995-02-14

    This notice with comment period sets forth a revised schedule of limits on home health agency costs that may be paid under the Medicare program for cost reporting periods beginning on or after July 1, 1993. These limits replace the per-visit limits that were set forth in our July 8, 1993 notice with comment period (58 FR 36748). This notice also provides, in accordance with the provisions of the Omnibus Budget Reconciliation Act of 1993 (OBRA '93), that there will be no changes in the home health agency (HHA) cost limits for cost reporting periods beginning on or after July 1, 1994, and before July 1, 1996. In addition, this notice responds to public comments on the July 8, 1993 notice with comment period, which originally set forth the HHA cost limits for cost reporting periods beginning on or after July 1, 1993, and on the January 6, 1994 notice with comment period (59 FR 760), which announced the elimination of the hospital based add-on effective for cost reporting periods beginning on or after October 1, 1993.

  1. 76 FR 54223 - Notice of Proposed Administrative Cost Recovery Settlement Pursuant to the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Logistics Base Barstow, CA AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY: In accordance with... for the Recovery of Past Costs in the Matter of Marine Corps Logistics Base, Yermo Annex, Barstow... Marine Corps Logistics Base in Barstow, California (the ``Site''), located in San Bernardino...

  2. 78 FR 940 - Proposed Administrative Cost Recovery Settlement Under Section 122(h) of the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... Environmental Response Compensation and Liability Act, as Amended, Former W&J Lanyon Zinc Works Superfund Site... with MCP Industries, Inc., for compromise of past response costs concerning the Former W&J Lanyon Zinc... Zinc Works Superfund Site, EPA Docket No. CERCLA-07-2012-0012. Comments should be addressed to:...

  3. 78 FR 7776 - Notice of Administrative Settlement Agreement for Recovery of Past Response Costs Pursuant to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... of the Proposed Agreement may be obtained from Robin E. Eiseman (3RC41), Senior Assistant Regional... Past Response Costs'' and ``EPA Docket No. CERCLA-03-2013- 0018DC,'' and should be forwarded to Robin E. Eiseman at the above address. FOR FURTHER INFORMATION CONTACT: Robin E. Eiseman (3RC41),...

  4. [Business administration of PET facilities: a nationwide survey for prices of PET screening and a cost analysis of three facilities].

    PubMed

    Mitsutake, Naohiro; Fujii, Ryo; Oku, Shinya; Furui, Yuji; Yasunaga, Hideo

    2007-05-01

    The purpose of this study is to analyze the business administration of PET facilities based on the survey of the price of PET cancer screening and cost analysis of PET examination. The questionnaire survey of the price of PET cancer screening was implemented for all PET facilities in Japan. Cost data of PET examination, including fixed costs and variable costs, were obtained from three different medical institutions. The marked price of the PET cancer screening was 111,499 yen in average, and the most popular range of prices was between 80,000 yen and 90,000 yen. Costs of PET per examination were accounted for 110,675 yen, 79,158 yen and Y11,644 yen in facility A, B and C, respectively. The results suggested that facilities with two or more PET/CT per a cyclotron could only secure profits. In Japan, the boom in PET facility construction could not continue in accordance with increasing number of PET facilities. It would become more essential to analyze the appropriate distribution of PET facilities and the adequate amount of PET procedures from the perspective of efficient utilization of the PET equipments and supply of PET-related healthcare.

  5. Confronting the challenge of greenline parks: Limits of the traditional administrative approach

    NASA Astrophysics Data System (ADS)

    Belcher, Elizabeth H.; Douglas Wellman, J.

    1991-05-01

    The National Park Service, like other natural resource management agencies, has adopted the traditional model of public administration, which emphasizes efficiency, effectiveness, economy, and dichotomy between politics and administration. This approach is particularly ineffective in greenline parks and increasingly inappropriate in traditional areas. In an era of ecological interdependence, relationships with other agencies and jurisdictions and with adjacent as well as noncontiguous landowners are as important as controlling visitors. Recreation managers need to develop more skill in negotiation, cooperation, coordination, and interpersonal communication if they are to preserve and protect park resources.

  6. The Medicare Cost Report and the limits of hospital accountability: improving financial accounting data.

    PubMed

    Kane, N M; Magnus, S A

    2001-02-01

    Health policy makers, legislators, providers, payers, and a broad range of other players in the health care market routinely seek information on hospital financial performance. Yet the data at their disposal are limited, especially since hospitals' audited financial statements--the "gold standard" in hospital financial reporting--are not publicly available in many states. As a result, the Medicare Cost Report (MCR), filed annually by most U.S. hospitals in order to receive payment for treating Medicare patients, has become the primary public source of hospital financial information. However, financial accounting elements in the MCR are unreliable, poorly defined, and lacking in critical detail. Comparative analyses of MCRs and matched, audited financial statements reveal long-standing problems with the MCR's data, including major differences in reported profits; variations in the reporting of both revenues and expenses; an absence of relevant details, such as charity care, bad debt, operating versus nonoperating income, and affiliate transactions; an inconsistent classification of changes in net assets; and a failure to provide cash flow statements. Because of these problems, MCR financial data give only a limited and often inaccurate picture of the financial position of hospitals. Audited financial statements provide a more complete perspective, enabling analysts to address important questions left unanswered by the MCR data. Regulatory action is needed to create a national database of financial information based upon audited statements.

  7. Low-cost assays for monitoring HIV infected individuals in resource-limited settings

    PubMed Central

    Balakrishnan, Pachamuthu; Iqbal, Hussain Syed; Shanmugham, Saravanan; Mohanakrishnan, Janardhanan; Solomon, Sunil S.; Mayer, Kenneth H.; Solomon, Suniti

    2011-01-01

    Use of a combination of CD4 counts and HIV viral load testing in the management of antiretroviral therapy (ART) provides higher prognostic estimation of the risk of disease progression than does the use of either test alone. The standard methods to monitor HIV infection are flow cytometry based for CD4+ T cell count and molecular assays to quantify plasma viral load of HIV. Commercial assays have been routinely used in developed countries to monitor ART. However, these assays require expensive equipment and reagents, well trained operators, and established laboratory infrastructure. These requirements restrict their use in resource-limited settings where people are most afflicted with the HIV-1 epidemic. With the advent of low-cost and/or low-tech alternatives, the possibility of implementing CD4 count and viral load testing in the management of ART in resource-limited settings is increasing. However, an appropriate validation should have been done before putting them to use for patient testing. PMID:22310816

  8. Keep it simple, stupid. Administrative complexity raises costs, frustrates patients and hampers care.

    PubMed

    Jessee, William F

    2004-03-01

    The administrative complexity of the U.S. health care system places an enormous wedge between our scientific capability and our performance in serving people promptly, affordably and inclusively. Those adverse effects have eroded public trust in health care and threaten the availability of physicians and other health workers to provide care for a growing and aging population. The author details the problem--and offers a solution.

  9. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.47 Limited disclosure of certain confidential...

  10. Limitations on Change: Current Conditions Influencing Academic Intransigence in Educational Administration Programs.

    ERIC Educational Resources Information Center

    Logan, Connie Stokes; Pounder, Diana G.

    An analysis of academic intransigence (resistance to change) in educational administrative preparation programs is presented in this paper. Drawing upon two conceptual frameworks, the stakeholder perspective and Porter's (1980) five-force model of industry structure and competitive influence, two factors contributing to academic intransigence are…

  11. Administrative and Holding Costs Resulting from Processing Reports of Nonconforming Supplies

    DTIC Science & Technology

    1989-07-01

    of a nonconforming item. The intent was to estimate these costs for individual items identified by Federal Supply Class (FSC), Federal Supply Group ...item to a supporting supply activity if this item is believed to be conforming . However, a service depot may also discover a nonconforming item and... nonconforming item. The first step of the analysis was the determination of the proportions (probabilities) of conforming and nonconforming items at each

  12. Cost efficient operations: Challenge from NASA administrator and lessons learned from hunting sacred cows

    NASA Technical Reports Server (NTRS)

    Hornstein, Rhoda Shaller; Casasanta, Ralph; Hei, Donald J., Jr.; Hawkins, Frederick J.; Burke, Eugene S., Jr.; Todd, Jacqueline E.; Bell, Jerome A.; Miller, Raymond E.; Willoughby, John K.; Gardner, Jo Anne

    1996-01-01

    The conclusions and recommendations that resulted from NASA's Hunting Sacred Cows Workshop are summarized, where a sacred cow is a belief or assumption that is so well established that it appears to be unreasonably immune to criticism. A link was identified between increased complexity and increased costs, especially in relation to automation and autonomy. An identical link was identified for outsourcing and commercialization. The work of NASA's Cost Less team is reviewed. The following conclusions were stated by the Cost Less team and considered at the workshop: the way Nasa conducts business must change; NASA makes its best contributions to the public areas not addressed by other government organizations; the management tool used for the last 30 years is no longer suitable; the most important work on any program or project is carried out before the development or operations stages; automation should only be used to achieve autonomy if the reasons for automation are well understood, and NASA's most critical resources are its personnel.

  13. [Iron substitution in outpatients in Switzerland: Increase of costs associated with intravenous administration].

    PubMed

    Giger, Max; Achermann, Rita

    2013-01-01

    Iron anaemia and iron-deficient erythropoiesis are treated with oral iron supplements. For chronic haemodialysis or in the case of therapy failure or intolerance to oral iron therapy, intravenous supplements are administered. The costs of iron supplements borne by statutory health care insurance had strongly increased during the observation period from 2006 to 2010. Based on the invoice data of a large health insurance company with a market share of around 18 %, prescription data of iron preparations and laboratory tests were analysed and extrapolated to the Swiss population. During the 5-year observation period, costs of intravenous iron substitution increased by 16.5 m EUR (340.3 %) and the number of individuals treated by 243.5 %. A sharp rise was observed in women of menstruating age, which was mainly due to prescriptions issued by primary care physicians. More than 8 % of intravenous iron substitutions were administered without prior laboratory analysis,and must therefore be regarded as off-label use. A cost-benefit analysis is needed to demonstrate the additional value of intravenous over oral iron supplementation, and intravenous iron supplementation should be administered only to patients with proven iron deficiency.

  14. 5 CFR 530.203 - Administration of aggregate limitation on pay.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... limitation on pay. (a) Except as provided in paragraph (b) of this section, no executive branch employee or General Schedule employee in the legislative branch (or General Schedule employee in the judicial branch... aggregate limitation. In such cases, the employee will become indebted to the Federal Government for...

  15. The Costs of Delivering Integrated HIV and Sexual Reproductive Health Services in Limited Resource Settings

    PubMed Central

    Obure, Carol Dayo; Sweeney, Sedona; Darsamo, Vanessa; Michaels-Igbokwe, Christine; Guinness, Lorna; Terris-Prestholt, Fern; Muketo, Esther; Nhlabatsi, Zelda; Warren, Charlotte E.; Mayhew, Susannah; Watts, Charlotte; Vassall, Anna

    2015-01-01

    Objective To present evidence on the total costs and unit costs of delivering six integrated sexual reproductive health and HIV services in a high and medium HIV prevalence setting, in order to support policy makers and planners scaling up these essential services. Design A retrospective facility based costing study conducted in 40 non-government organization and public health facilities in Kenya and Swaziland. Methods Economic and financial costs were collected retrospectively for the year 2010/11, from each study site with an aim to estimate the cost per visit of six integrated HIV and SRH services. A full cost analysis using a combination of bottom-up and step-down costing methods was conducted from the health provider’s perspective. The main unit of analysis is the economic unit cost per visit for each service. Costs are converted to 2013 International dollars. Results The mean cost per visit for the HIV/SRH services ranged from $Int 14.23 (PNC visit) to $Int 74.21 (HIV treatment visit). We found considerable variation in the unit costs per visit across settings with family planning services exhibiting the least variation ($Int 6.71-52.24) and STI treatment and HIV treatment visits exhibiting the highest variation in unit cost ranging from ($Int 5.44-281.85) and ($Int 0.83-314.95), respectively. Unit costs of visits were driven by fixed costs while variability in visit costs across facilities was explained mainly by technology used and service maturity. Conclusion For all services, variability in unit costs and cost components suggest that potential exists to reduce costs through better use of both human and capital resources, despite the high proportion of expenditure on drugs and medical supplies. Further work is required to explore the key drivers of efficiency and interventions that may facilitate efficiency improvements. PMID:25933414

  16. Costs of mating competition limit male lifetime breeding success in polygynous mammals

    PubMed Central

    Lukas, Dieter; Clutton-Brock, Tim

    2014-01-01

    Although differences in breeding lifespan are an important source of variation in male fitness, the factors affecting the breeding tenure of males have seldom been explored. Here, we use cross-species comparisons to investigate the correlates of breeding lifespan in male mammals. Our results show that male breeding lifespan depends on the extent of polygyny, which reflects the relative intensity of competition for access to females. Males have relatively short breeding tenure in species where individuals have the potential to monopolize mating with multiple females, and longer ones where individuals defend one female at a time. Male breeding tenure is also shorter in species in which females breed frequently than in those where females breed less frequently, suggesting that the costs of guarding females may contribute to limiting tenure length. As a consequence of these relationships, estimates of skew in male breeding success within seasons overestimate skew calculated across the lifetime and, in several polygynous species, variance in lifetime breeding success is not substantially higher in males than in females. PMID:24827443

  17. Costs of mating competition limit male lifetime breeding success in polygynous mammals.

    PubMed

    Lukas, Dieter; Clutton-Brock, Tim

    2014-07-07

    Although differences in breeding lifespan are an important source of variation in male fitness, the factors affecting the breeding tenure of males have seldom been explored. Here, we use cross-species comparisons to investigate the correlates of breeding lifespan in male mammals. Our results show that male breeding lifespan depends on the extent of polygyny, which reflects the relative intensity of competition for access to females. Males have relatively short breeding tenure in species where individuals have the potential to monopolize mating with multiple females, and longer ones where individuals defend one female at a time. Male breeding tenure is also shorter in species in which females breed frequently than in those where females breed less frequently, suggesting that the costs of guarding females may contribute to limiting tenure length. As a consequence of these relationships, estimates of skew in male breeding success within seasons overestimate skew calculated across the lifetime and, in several polygynous species, variance in lifetime breeding success is not substantially higher in males than in females.

  18. Medicare program; invalidation of the wage index in the schedule of limits on Hospital per diem inpatient general routine operating costs for cost reporting periods beginning on or after July 1, 1981 and ending with cost reporting periods beginning on or before September 30, 1982--HCFA. Notice.

    PubMed

    1983-09-02

    This notice announces the April 29, 1983 decision of the United States District Court for the District of Columbia in the case of District of Columbia Hospital Association, et al. v. Heckler, et al. (No. 82-2520 D.D.C.). In its decision, the court ordered us to publish a notice in the Federal Register stating that the 1981 schedule of limits on hospital per diem inpatient general routine operating costs has been declared invalid with regard to the wage index for cost reporting periods beginning on or before July 1, 1981 and ending with cost reporting periods beginning on or before September 30, 1982. The District Court held that the decision to exclude Federal government hospital wage data from the computation of the wage index used in the 1981 Medicare hospital cost limits, without providing prior notice and an opportunity for comment, was in violation of the rulemaking requirements of the Administrative Procedure Act. The decision of the District Court does not apply to cost reporting periods beginning on or after October 1, 1982. The cost limits for periods beginning on or after October 1, 1982 are contained in the interim final notice with comment period published in the Federal Register on September 30, 1982 (47 FR 43296).

  19. 78 FR 43972 - Amendments to the Export Administration Regulations: Implementation of Limited Syria Waiver for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... export or reexport of certain commodities, software, and technology necessary for the support of the... export or reexport of certain commodities, software, and technology, including, but not limited to, those related to water supply and sanitation, agricultural production and food processing, power generation,...

  20. Inclusion of costs in conservation planning depends on limited datasets and hopeful assumptions.

    PubMed

    Armsworth, Paul R

    2014-08-01

    Many conservation organizations use spatial prioritization to help identify locations in which to work. Increasingly, prioritizations seek to account for spatial heterogeneity in the costs of conservation, motivated in part by claims of large efficiency savings when these costs are included. I critically review the cost estimates on which such claims are based, focusing on acquisition and management costs associated with terrestrial protected areas. If researchers are to evaluate how including costs affects conservation planning outcomes, estimation methods need to preserve the covariation between and relative variation within costs and benefits of conservation activities. However, widely used methods for estimating costs and incorporating them into prioritizations may not meet these standards. For example, among relevant studies, there is surprisingly little attention given to the costs that conservation organizations actually face. Instead, there is a heavy reliance on untested proxies for conservation costs. Analytical shortcuts are also common. Now that debate is moving beyond whether to account for costs in conservation planning, it is time to evaluate just how we can include them to greatest effect.

  1. Limited susceptibility of cynomolgus monkeys (Macaca fascicularis) to leprosy after experimental administration of Mycobacterium leprae.

    PubMed

    Walsh, Gerald P; Dela Cruz, Eduardo C; Abalos, Rodolfo M; Tan, Esterlina V; Fajardo, Tranquilino T; Villahermosa, Laarni G; Cellona, Roland V; Balagon, Maria V; White, Valerie A; Saunderson, Paul R; Walsh, Douglas S

    2012-08-01

    Cynomolgus monkeys are a useful model for human tuberculosis, but susceptibility to M. leprae is unknown. A cynomolgus model of leprosy could increase understanding of pathogenesis-importantly, neuritis and nerve-damaging reactions. We administered viable Mycobacterium leprae to 24 cynomolgus monkeys by three routes, with a median follow-up period of 6 years (range = 1-19 years) involving biopsies, nasal smears, antiphenolic glycolipid-1 (PGL-1) antibody serology, and lepromin skin testing. Most developed evanescent papules at intradermal M. leprae inoculation sites that, on biopsy, showed a robust cellular immune response akin to a lepromin skin test reaction; many produced PGL-1 antibodies. At necropsy, four monkeys, without cutaneous or gross neurological signs of leprosy but with elevated PGL-1 antibodies, including three with nasal smears (+) for acid fast bacilli (AFB), showed histological features, including AFB, suggestive of leprosy at several sites. Overall, however, cynomolgus monkeys seem minimally susceptible to leprosy after experimental M. leprae administration.

  2. Administration of neuropsychological tests using interactive voice response technology in the elderly: validation and limitations.

    PubMed

    Miller, Delyana Ivanova; Talbot, Vincent; Gagnon, Michèle; Messier, Claude

    2013-01-01

    Interactive voice response (IVR) systems are computer programs, which interact with people to provide a number of services from business to health care. We examined the ability of an IVR system to administer and score a verbal fluency task (fruits) and the digit span forward and backward in 158 community dwelling people aged between 65 and 92 years of age (full scale IQ of 68-134). Only six participants could not complete all tasks mostly due to early technical problems in the study. Participants were also administered the Wechsler Intelligence Scale fourth edition (WAIS-IV) and Wechsler Memory Scale fourth edition subtests. The IVR system correctly recognized 90% of the fruits in the verbal fluency task and 93-95% of the number sequences in the digit span. The IVR system typically underestimated the performance of participants because of voice recognition errors. In the digit span, these errors led to the erroneous discontinuation of the test: however the correlation between IVR scoring and clinical scoring was still high (93-95%). The correlation between the IVR verbal fluency and the WAIS-IV Similarities subtest was 0.31. The correlation between the IVR digit span forward and backward and the in-person administration was 0.46. We discuss how valid and useful IVR systems are for neuropsychological testing in the elderly.

  3. The Economics of Perception: Potential Effect regarding Institutional Uses of Recovered Facilities and Administrative Costs upon a Faculty Member's Decision to Engage in Sponsored Research Activity

    ERIC Educational Resources Information Center

    Hatfield, Anne Elizabeth

    2012-01-01

    There is one aspect of sponsored research associated with higher education's research enterprise that often places the institution's research administrators and the institution's faculty members in conflict with each other; the recovery of Facilities and Administrative (F&A) costs associated with sponsored research projects (Sedwick, 2009;…

  4. 26 CFR 1.1059A-1 - Limitation on taxpayer's basis or inventory cost in property imported from related persons.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... any way the authority of the Commissioner to increase or decrease the claimed basis or inventory cost... liquidated upon importation, the section 1059A limitation on the undervalued article may be increased up to... increased by the amount of the duty over-paid on Article B, $.20, times 1/.10, up to the amount of...

  5. Limiter

    DOEpatents

    Cohen, S.A.; Hosea, J.C.; Timberlake, J.R.

    1984-10-19

    A limiter with a specially contoured front face is provided. The front face of the limiter (the plasma-side face) is flat with a central indentation. In addition, the limiter shape is cylindrically symmetric so that the limiter can be rotated for greater heat distribution. This limiter shape accommodates the various power scrape-off distances lambda p, which depend on the parallel velocity, V/sub parallel/, of the impacting particles.

  6. 15 CFR 24.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Allowable costs. 24.22 Section 24.22... Administration § 24.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees and cost-type contractors, including allowable costs in...

  7. 50 CFR 37.46 - Cost reimbursement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Cost reimbursement. 37.46 Section 37.46... NATIONAL WILDLIFE REFUGE, ALASKA General Administration § 37.46 Cost reimbursement. (a) Each applicant for... actual costs incurred, including, but not limited to, its direct costs and indirect costs as...

  8. Limiter

    DOEpatents

    Cohen, Samuel A.; Hosea, Joel C.; Timberlake, John R.

    1986-01-01

    A limiter with a specially contoured front face accommodates the various power scrape-off distances .lambda..sub.p, which depend on the parallel velocity, V.sub..parallel., of the impacting particles. The front face of the limiter (the plasma-side face) is flat with a central indentation. In addition, the limiter shape is cylindrically symmetric so that the limiter can be rotated for greater heat distribution.

  9. The Benefits, Limitations, and Cost-Effectiveness of Advanced Technologies in the Management of Patients With Diabetes Mellitus

    PubMed Central

    Vigersky, Robert A.

    2015-01-01

    Background: Hypoglycemia mitigation is critical for appropriately managing patients with diabetes. Advanced technologies are becoming more prevalent in diabetes management, but their benefits have been primarily judged on the basis of hemoglobin A1c. A critical appraisal of the effectiveness and limitations of advanced technologies in reducing both A1c and hypoglycemia rates has not been previously performed. Methods: The cost of hypoglycemia was estimated using literature rates of hypoglycemia events resulting in hospitalizations. A literature search was conducted on the effect on A1c and hypoglycemia of advanced technologies. The cost-effectiveness of continuous subcutaneous insulin infusion (CSII) and real-time continuous glucose monitors (RT-CGM) was reviewed. Results: Severe hypoglycemia in insulin-using patients with diabetes costs $4.9-$12.7 billion. CSII reduces A1c in some but not all studies. CSII improves hypoglycemia in patients with high baseline rates. Bolus calculators improve A1c and improve the fear of hypoglycemia but not hypoglycemia rates. RT-CGM alone and when combined with CSII improve A1c with a neutral effect on hypoglycemia rates. Low-glucose threshold suspend systems reduce hypoglycemia with a neutral effect on A1c, and low-glucose predictive suspend systems reduce hypoglycemia with a small increase in plasma glucose levels. In short-term studies, artificial pancreas systems reduce both hypoglycemia rates and plasma glucose levels. CSII and RT-CGM are cost-effective technologies, but their wide adoption is limited by cost, psychosocial, and educational factors. Conclusions: Most currently available technologies improve A1c with a neutral or improved rate of hypoglycemia. Advanced technologies appear to be cost-effective in diabetes management, especially when including the underlying cost of hypoglycemia. PMID:25555391

  10. 38 CFR 21.258 - Cost limitations on approval of self-employment plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C....

  11. Limited encoding of effort by dopamine neurons in a cost-benefit trade-off task

    PubMed Central

    Pasquereau, Benjamin; Turner, Robert S.

    2013-01-01

    Animals are thought to evaluate the desirability of action options using a unified scale that combines predicted benefits (“rewards”), costs, and the animal’s internal motivational state. Midbrain dopamine neurons have long been associated with the reward part of this equation, but it is unclear whether these neurons also estimate the costs of taking an action. We studied the spiking activity of dopamine neurons in the substantia nigra pars compacta of monkeys (Macaca mulatta) during a reaching task in which the energetic costs incurred (friction loads) and the benefits gained (drops of food) were manipulated independently. Although the majority of dopamine neurons encoded the upcoming reward alone, a subset predicted net utility of a course of action by signaling the expected reward magnitude, discounted by the invested cost in terms of physical effort. In addition, the tonic activity of some dopamine neurons was slowly reduced in conjunction with the accumulated trials, which is consistent with the hypothesized role for tonic dopamine in the invigoration or motivation of instrumental responding. The present results shed light on an oft-hypothesized role for dopamine in the regulation of the balance in natural behaviors between the energy expended and the benefits gained, which could explain why dopamine disorders, such as Parkinson’s disease, lead to a breakdown of that balance. PMID:23658169

  12. Local Property Tax Limitations vs. School District Employee Pension Costs in Pennsylvania

    ERIC Educational Resources Information Center

    Hartman, William T.; Shrom, Timothy J.

    2014-01-01

    In Pennsylvania as in many other states, employee pension costs are a significant source of financial pressure for school districts (Zeehandelaar and Northern 2013, Pennsylvania Public Employees' Retirement Commission 2013). In order to gain greater insight into the nature of Pennsylvania school districts' financial burden related to pension…

  13. 40 CFR 35.925-18 - Limitation upon project costs incurred prior to award.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works... authorized for step 1 or step 2 project work performed before award of a step 1 or step 2 grant. However... project costs in the following cases: (1) Step 1 work begun after the date of approval by the...

  14. Scope-of-practice laws for nurse practitioners limit cost savings that can be achieved in retail clinics.

    PubMed

    Spetz, Joanne; Parente, Stephen T; Town, Robert J; Bazarko, Dawn

    2013-11-01

    Retail clinics have the potential to reduce health spending by offering convenient, low-cost access to basic health care services. Retail clinics are often staffed by nurse practitioners (NPs), whose services are regulated by state scope-of-practice regulations. By limiting NPs' work scope, restrictive regulations could affect possible cost savings. Using multistate insurance claims data from 2004-07, a period in which many retail clinics opened, we analyzed whether the cost per episode associated with the use of retail clinics was lower in states where NPs are allowed to practice independently and to prescribe independently. We also examined whether retail clinic use and scope of practice were associated with emergency department visits and hospitalizations. We found that visits to retail clinics were associated with lower costs per episode, compared to episodes of care that did not begin with a retail clinic visit, and the costs were even lower when NPs practiced independently. Eliminating restrictions on NPs' scope of practice could have a large impact on the cost savings that can be achieved by retail clinics.

  15. Shared networks of interpreter services, at relatively low cost, can help providers serve patients with limited english skills.

    PubMed

    Jacobs, Elizabeth A; Leos, Ginelle Sanchez; Rathouz, Paul J; Fu, Paul

    2011-10-01

    Language barriers in health care-a large and growing problem in the United States-contribute to disparities in health care quality and outcomes in populations with limited English proficiency. Providing access to adequate interpreter services has been shown to reduce health disparities in these populations. However, many health care organizations do not provide such services because of the perceived high cost. In this observational study we calculated the costs incurred by a group of California public hospitals that formed a network to make trained interpreters available via videoconference and telephone. We found that encounters in this network where interpreters helped patients and providers communicate lasted an average of 10.6 minutes and cost an average of $24.86 per encounter. Such costs should be weighed against the likely alternatives, such as the opportunity costs of having other hospital staff act as ad hoc interpreters; medical errors that could result from inadequate interpretation; and the fact that not providing such services may leave providers out of compliance with federal law. We also discuss ways in which providers could be compensated for providing interpreter services.

  16. Modular Laboratories—Cost-Effective and Sustainable Infrastructure for Resource-Limited Settings

    PubMed Central

    Bridges, Daniel J.; Colborn, James; Chan, Adeline S. T.; Winters, Anna M.; Dengala, Dereje; Fornadel, Christen M.; Kosloff, Barry

    2014-01-01

    High-quality laboratory space to support basic science, clinical research projects, or health services is often severely lacking in the developing world. Moreover, the construction of suitable facilities using traditional methods is time-consuming, expensive, and challenging to implement. Three real world examples showing how shipping containers can be converted into modern laboratories are highlighted. These include use as an insectary, a molecular laboratory, and a BSL-3 containment laboratory. These modular conversions have a number of advantages over brick and mortar construction and provide a cost-effective and timely solution to offer high-quality, user-friendly laboratory space applicable within the developing world. PMID:25223943

  17. Limiting the public cost of stationary battery deployment by combining applications

    NASA Astrophysics Data System (ADS)

    Stephan, A.; Battke, B.; Beuse, M. D.; Clausdeinken, J. H.; Schmidt, T. S.

    2016-07-01

    Batteries could be central to low-carbon energy systems with high shares of intermittent renewable energy sources. However, the investment attractiveness of batteries is still perceived as low, eliciting calls for policy to support deployment. Here we show how the cost of battery deployment can potentially be minimized by introducing an aspect that has been largely overlooked in policy debates and underlying analyses: the fact that a single battery can serve multiple applications. Batteries thereby can not only tap into different value streams, but also combine different risk exposures. To address this gap, we develop a techno-economic model and apply it to the case of lithium-ion batteries serving multiple stationary applications in Germany. Our results show that batteries could be attractive for investors even now if non-market barriers impeding the combination of applications were removed. The current policy debate should therefore be refocused so as to encompass the removal of such barriers.

  18. Effects of cryptic mortality and the hidden costs of using length limits in fishery management

    USGS Publications Warehouse

    Coggins, L.G.; Catalano, M.J.; Allen, M.S.; Pine, William E.; Walters, C.J.

    2007-01-01

    Fishery collapses cause substantial economic and ecological harm, but common management actions often fail to prevent overfishing. Minimum length limits are perhaps the most common fishing regulation used in both commercial and recreational fisheries, but their conservation benefits can be influenced by discard mortality of fish caught and released below the legal length. We constructed a computer model to evaluate how discard mortality could influence the conservation utility of minimum length regulations. We evaluated policy performance across two disparate fish life-history types: short-lived high-productivity (SLHP) and long-lived low-productivity (LLLP) species. For the life-history types, fishing mortality rates and minimum length limits that we examined, length limits alone generally failed to achieve sustainability when discard mortality rate exceeded about 0.2 for SLHP species and 0.05 for LLLP species. At these levels of discard mortality, reductions in overall fishing mortality (e.g. lower fishing effort) were required to prevent recruitment overfishing if fishing mortality was high. Similarly, relatively low discard mortality rates (>0.05) rendered maximum yield unobtainable and caused a substantial shift in the shape of the yield response surfaces. An analysis of fishery efficiency showed that length limits caused the simulated fisheries to be much less efficient, potentially exposing the target species and ecosystem to increased negative effects of the fishing process. Our findings suggest that for overexploited fisheries with moderate-to-high discard mortality rates, reductions in fishing mortality will be required to meet management goals. Resource managers should carefully consider impacts of cryptic mortality sources (e.g. discard mortality) on fishery sustainability, especially in recreational fisheries where release rates are high and effort is increasing in many areas of the world. ?? 2007 Blackwell Publishing Ltd.

  19. Local infiltration of rabies immunoglobulins without systemic intramuscular administration: An alternative cost effective approach for passive immunization against rabies

    PubMed Central

    Bharti, Omesh Kumar; Madhusudana, Shampur Narayan; Gaunta, Pyare Lal; Belludi, Ashwin Yajaman

    2016-01-01

    ABSTRACT Presently the dose of rabies immunoglobulin (RIG) which is an integral part of rabies post exposure prophylaxis (PEP) is calculated based on body weight though the recommendation is to infiltrate the wound(s). This practice demands large quantities of RIG which may be unaffordable to many patients. In this background, we conducted this study to know if the quantity and cost of RIG can be reduced by restricting passive immunization to local infiltration alone and avoiding systemic intramuscular administration based on the available scientific evidence. Two hundred and sixty nine category III patients bitten by suspect or confirmed rabid dogs/animals were infiltrated with equine rabies immunoglobulin (ERIGs) in and around the wound. The quantity of ERIG used was proportionate to the size and number of wounds irrespective of their body weight. They were followed with a regular course of rabies vaccination by intra-dermal route. As against 363 vials of RIGs required for all these cases as per current recommendation based on body weight, they required only 42 vials of 5ml RIG. Minimum dose of RIGs given was 0.25 ml and maximum dose given was 8 ml. On an average 1.26 ml of RIGs was required per patient that costs Rs. 150 ($3). All the patients were followed for 9 months and they were healthy and normal at the end of observation period. With local infiltration, that required small quantities of RIG, the RIGs could be made available to all patients in times of short supply in the market. A total of 30 (11%) serum samples of patients were tested for rabies virus neutralizing antibodies by the rapid fluorescent focus inhibition test (RFFIT) and all showed antibody titers >0.5 IU/mL by day 14. In no case the dose was higher than that required based on body weight and no immunosuppression resulted. To conclude, this pilot study shows that local infiltration of RIG need to be considered in times of non-availability in the market or unaffordability by poor patients

  20. 34 CFR 692.72 - May a State use the funds it receives under the SLEAP Program to pay administrative costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false May a State use the funds it receives under the SLEAP... Is the Amount of Assistance and How May It Be Used? § 692.72 May a State use the funds it receives under the SLEAP Program to pay administrative costs? A State may not use any of the funds it...

  1. 29 CFR 4903.6 - How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC? 4903.6 Section 4903.6 Labor Regulations Relating to Labor (Continued... Procedures To Collect Debts Owed to PBGC § 4903.6 How will PBGC add interest, penalty charges,...

  2. 29 CFR 4903.6 - How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC? 4903.6 Section 4903.6 Labor Regulations Relating to Labor (Continued... Procedures To Collect Debts Owed to PBGC § 4903.6 How will PBGC add interest, penalty charges,...

  3. 29 CFR 4903.6 - How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC? 4903.6 Section 4903.6 Labor Regulations Relating to Labor (Continued... Procedures To Collect Debts Owed to PBGC § 4903.6 How will PBGC add interest, penalty charges,...

  4. 29 CFR 4903.6 - How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false How will PBGC add interest, penalty charges, and administrative costs to a debt owed to PBGC? 4903.6 Section 4903.6 Labor Regulations Relating to Labor (Continued... Procedures To Collect Debts Owed to PBGC § 4903.6 How will PBGC add interest, penalty charges,...

  5. 78 FR 48868 - Proposed Cercla Administrative Cost Recovery Settlement; MassDOT, MassDOT Route 1 Right-of-Way...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed Cercla Administrative Cost Recovery Settlement; MassDOT, MassDOT Route 1 Right-of-Way... Environmental Response Compensation, and Liability Act, as amended (``CERCLA''), 42 U.S.C....

  6. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 4 2013-07-01 2013-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION...

  7. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 4 2012-07-01 2012-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION...

  8. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 4 2014-07-01 2014-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION...

  9. Persistent palatable food preference in rats with a history of limited and extended access to methamphetamine self-administration.

    PubMed

    Caprioli, Daniele; Zeric, Tamara; Thorndike, Eric B; Venniro, Marco

    2015-09-01

    Recent studies have shown that when given a mutually exclusive choice between cocaine and palatable foods, most rats prefer the non-drug rewards over cocaine. Here, we used a discrete choice procedure to assess whether palatable food preference generalizes to rats with a history of limited (3 hours/day) or extended (6 or 9 hours/day) access to methamphetamine self-administration. On different daily sessions, we trained rats to lever-press for either methamphetamine (0.1-0.2 mg/kg/infusion) or palatable food (five pellets per reward delivery) for several weeks; regular food was freely available. We then assessed food-methamphetamine preference either during training, after priming methamphetamine injections (0.5-1.0 mg/kg), following a satiety manipulation (palatable food exposure in the home cage) or after 21 days of withdrawal from methamphetamine. We also assessed progressive ratio responding for palatable food and methamphetamine. We found that independent of the daily drug access conditions and the withdrawal period, the rats strongly preferred the palatable food over methamphetamine, even when they were given free access to the palatable food in the home cage. Intake of methamphetamine and progressive ratio responding for the drug, both of which increased or escalated over time, did not predict preference in the discrete choice test. Results demonstrate that most rats strongly prefer palatable food pellets over intravenous methamphetamine, confirming previous studies using discrete choice procedures with intravenous cocaine. Results also demonstrate that escalation of drug self-administration, a popular model of compulsive drug use, is not associated with a cardinal feature of human addiction of reduced behavioral responding for non-drug rewards.

  10. Persistent palatable food preference in rats with a history of limited and extended access to methamphetamine self-administration

    PubMed Central

    Caprioli, Daniele; Zeric, Tamara; Thorndike, Eric B; Venniro, Marco

    2015-01-01

    Recent studies have shown that when given a mutually exclusive choice between cocaine and palatable foods most rats prefer the non-drug rewards over cocaine. Here, we used a discrete choice procedure to assess whether palatable food preference generalizes to rats with a history of limited (3 hr/day) or extended (6 or 9 hr/day) access to methamphetamine self-administration. On different daily sessions, we trained rats to lever-press for either methamphetamine (0.1–0.2 mg/kg/infusion) or palatable food (5 pellets per reward delivery) for several weeks; regular food was freely available. We then assessed food-methamphetamine preference either during training, after priming methamphetamine injections (0.5–1.0 mg/kg), following a satiety manipulation (palatable food exposure in the home cage), or after 21 days of withdrawal from methamphetamine. We also assessed progressive ratio responding for palatable food and methamphetamine. We found that independent of the daily drug access conditions and the withdrawal period, the rats strongly preferred the palatable food over methamphetamine, even when they were given free access to the palatable food in the home cage. Intake of methamphetamine and progressive ratio responding for the drug, both of which increased or escalated over time, did not predict preference in the discrete choice test. Results demonstrate that most rats strongly prefer palatable food pellets over intravenous methamphetamine, confirming previous studies using discrete choice procedures with intravenous cocaine. Results also demonstrate that escalation of drug self-administration, a popular model of compulsive drug use, is not associated with a cardinal feature of human addiction of reduced behavioral responding for non-drug rewards. PMID:25582886

  11. 45 CFR 92.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Allowable costs. 92.22 Section 92.22 Public... Financial Administration § 92.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees and cost-type contractors,...

  12. 29 CFR 1470.22 - Allowable costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Allowable costs. 1470.22 Section 1470.22 Labor Regulations... Financial Administration § 1470.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees and cost-type contractors,...

  13. 38 CFR 43.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Allowable costs. 43.22... Requirements Financial Administration § 43.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees and cost-type...

  14. Analysis of EPA`s cost-effectiveness study for the coastal oil and gas effluent limitations guidelines

    SciTech Connect

    Veil, J.

    1995-05-01

    The US Environmental Protection Agency (EPA) conducted a cost-effectiveness (CE) analysis to estimate the incremental cost of complying with the proposed effluent limitation guidelines (ELGs) for the coastal oil and gas industry (EPA 1995a). EPA`s CE analysis calculates the pounds of each pollutant that would be removed if the chosen discharge option is selected. In 1993, EPA issued final ELGs for the offshore oil and gas industry and published an offshore CE analysis. The chemical characteristics of produced water from the offshore region are essentially the same as those of produced water from the coastal region. It was surprising, therefore, that EPA chose a much longer list of pollutants and generally stricter weighting factors for the coastal CE analysis. This report reviews the data, assumptions, and analyses used in EPA`s coastal CE analysis and identifies alternate data, assumptions, and analyses that could lead to significantly different cost-effectiveness conclusions. Two alternate lists of pollutants are proposed, along with recalculated weighting factors for several pollutants that contributed a large proportion of the total PEs removed--radium, benzo(a)pyrene, boron, and ammonia. By using different combinations of these variables, a range of revised estimates of CE is calculated.

  15. Space Shuttle main engine. NASA has not evaluated the alternate fuel turbopump costs and benefits. Report to the Administrator of the National Aeronautics and Space Administration

    NASA Astrophysics Data System (ADS)

    1993-10-01

    NASA's plans to develop an alternate high pressure fuel turbopump for the Space Shuttle's main engines were assessed by the General Accounting Office as a part of the evaluation of the Space Shuttle Safety and Obsolescence Upgrade program. The objective was to determine whether NASA has adequately analyzed cost, performance, and benefits that are expected to result from this program in comparison to other alternatives before resuming development of the alternate pump, which was suspended in 1992. The alternate fuel pump is one of five improvements being developed or planned to significantly enhance safety margins of the engines.

  16. Cost tradeoffs in consequence management at nuclear power plants: A risk based approach to setting optimal long-term interdiction limits for regulatory analyses

    SciTech Connect

    Mubayi, V.

    1995-05-01

    The consequences of severe accidents at nuclear power plants can be limited by various protective actions, including emergency responses and long-term measures, to reduce exposures of affected populations. Each of these protective actions involve costs to society. The costs of the long-term protective actions depend on the criterion adopted for the allowable level of long-term exposure. This criterion, called the ``long term interdiction limit,`` is expressed in terms of the projected dose to an individual over a certain time period from the long-term exposure pathways. The two measures of offsite consequences, latent cancers and costs, are inversely related and the choice of an interdiction limit is, in effect, a trade-off between these two measures. By monetizing the health effects (through ascribing a monetary value to life lost), the costs of the two consequence measures vary with the interdiction limit, the health effect costs increasing as the limit is relaxed and the protective action costs decreasing. The minimum of the total cost curve can be used to calculate an optimal long term interdiction limit. The calculation of such an optimal limit is presented for each of five US nuclear power plants which were analyzed for severe accident risk in the NUREG-1150 program by the Nuclear Regulatory Commission.

  17. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 4 2011-07-01 2011-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the... Amount of Assistance and How May It Be Used? § 692.112 May a State use the funds it receives from the...

  18. 34 CFR 692.72 - May a State use the funds it receives under the SLEAP Program to pay administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 4 2011-07-01 2011-07-01 false May a State use the funds it receives under the SLEAP... Program What Is the Amount of Assistance and How May It Be Used? § 692.72 May a State use the funds it receives under the SLEAP Program to pay administrative costs? A State may not use any of the funds...

  19. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the... Assistance and How May It Be Used? § 692.112 May a State use the funds it receives from the GAP Program...

  20. Isoprene emissions from downy oak under water limitation during an entire growing season: what cost for growth?

    PubMed

    Genard-Zielinski, Anne-Cyrielle; Ormeño, Elena; Boissard, Christophe; Fernandez, Catherine

    2014-01-01

    Increases in the production of terpene- and phenolic-like compounds in plant species under abiotic stress conditions have been interpreted in physiological studies as a supplementary defense system due to their capacity to limit cell oxidation. From an ecological perspective however, these increases are only expected to confer competitive advantages if they do not imply a significant cost for the plant, that is, growth reduction. We investigated shifts of isoprene emissions, and to a lesser extent phenolic compound concentration, of Quercus pubescens Willd. from early leaf development to leaf senescence under optimal watering (control: C), mild and severe water stress (MS, SS). The impact of water stress was concomitantly assessed on plant physiological (chlorophyll fluorescence, stomatal conductance, net photosynthesis, water potential) functional (relative leaf water content, leaf mass per area ratio) and growth (aerial and root biomass) traits. Growth changes allowed to estimate the eventual costs related to the production of isoprene and phenolics. The total phenolic content was not modified under water stress whereas isoprene emissions were promoted under MS over the entire growing cycle despite the decline of Pn by 35%. Under SS, isoprene emissions remained similar to C all over the study despite the decline of Pn by 47% and were thereby clearly uncoupled to Pn leading to an overestimation of the isoprene emission factor by 44%. Under SS, maintenance of isoprene emissions and phenolic compound concentration resulted in very significant costs for the plants as growth rates were very significantly reduced. Under MS, increases of isoprene emission and maintenance of phenolic compound concentration resulted in moderate growth reduction. Hence, it is likely that investment in isoprene emissions confers Q. pubescens an important competitive advantage during moderate but not severe periods of water scarcity. Consequences of this response for air quality in North

  1. Design of a Novel Low Cost Point of Care Tampon (POCkeT) Colposcope for Use in Resource Limited Settings

    PubMed Central

    Lam, Christopher T.; Krieger, Marlee S.; Gallagher, Jennifer E.; Asma, Betsy; Muasher, Lisa C.; Schmitt, John W.; Ramanujam, Nimmi

    2015-01-01

    Introduction Current guidelines by WHO for cervical cancer screening in low- and middle-income countries involves visual inspection with acetic acid (VIA) of the cervix, followed by treatment during the same visit or a subsequent visit with cryotherapy if a suspicious lesion is found. Implementation of these guidelines is hampered by a lack of: trained health workers, reliable technology, and access to screening facilities. A low cost ultra-portable Point of Care Tampon based digital colposcope (POCkeT Colposcope) for use at the community level setting, which has the unique form factor of a tampon, can be inserted into the vagina to capture images of the cervix, which are on par with that of a state of the art colposcope, at a fraction of the cost. A repository of images to be compiled that can be used to empower front line workers to become more effective through virtual dynamic training. By task shifting to the community setting, this technology could potentially provide significantly greater cervical screening access to where the most vulnerable women live. The POCkeT Colposcope’s concentric LED ring provides comparable white and green field illumination at a fraction of the electrical power required in commercial colposcopes. Evaluation with standard optical imaging targets to assess the POCkeT Colposcope against the state of the art digital colposcope and other VIAM technologies. Results Our POCkeT Colposcope has comparable resolving power, color reproduction accuracy, minimal lens distortion, and illumination when compared to commercially available colposcopes. In vitro and pilot in vivo imaging results are promising with our POCkeT Colposcope capturing comparable quality images to commercial systems. Conclusion The POCkeT Colposcope is capable of capturing images suitable for cervical lesion analysis. Our portable low cost system could potentially increase access to cervical cancer screening in limited resource settings through task shifting to community

  2. Incremental health care costs for chronic pain in Ontario, Canada: a population-based matched cohort study of adolescents and adults using administrative data.

    PubMed

    Hogan, Mary-Ellen; Taddio, Anna; Katz, Joel; Shah, Vibhuti; Krahn, Murray

    2016-08-01

    Little is known about the economic burden of chronic pain and how chronic pain affects health care utilization. We aimed to estimate the annual per-person incremental medical cost and health care utilization for chronic pain in the Ontario population from the perspective of the public payer. We performed a retrospective cohort study using Ontario health care databases and the electronically linked Canadian Community Health Survey (CCHS) from 2000 to 2011. We identified subjects aged ≥12 years from the CCHS with chronic pain and closely matched them to individuals without pain using propensity score matching methods. We used linked data to determine mean 1-year per-person health care costs and utilization for each group and mean incremental cost for chronic pain. All costs are reported in 2014 Canadian dollars. After matching, we had 19,138 pairs of CCHS respondents with and without chronic pain. The average age was 55 years (SD = 18) and 61% were female. The incremental cost to manage chronic pain was $1742 per person (95% confidence interval [CI], $1488-$2020), 51% more than the control group. The largest contributor to the incremental cost was hospitalization ($514; 95% CI, $364-$683). Incremental costs were the highest in those with severe pain ($3960; 95% CI, $3186-$4680) and in those with most activity limitation ($4365; 95% CI, $3631-$5147). The per-person cost to manage chronic pain is substantial and more than 50% higher than a comparable patient without chronic pain. Costs are higher in people with more severe pain and activity limitations.

  3. Overcoming the production limitations of Photorhabdus temperata ssp. temperata strain K122 bioinsecticides in low-cost medium.

    PubMed

    Jallouli, Wafa; Jaoua, Samir; Zouari, Nabil

    2011-10-01

    For low-cost production of Photorhabdus temperata ssp. temperata strain K122 bioinsecticide, a cheap complex medium was optimized. Diluted seawater was used as the source of micronutrients, especially sodium chloride, involved in the improvement of cell density, culturability and oral toxicity of the bacterium P. temperata against Ephestia kuehniella larvae. Thus, the new formulated medium was composed only of 10 g/l of soya bean meal, used as the carbon and nitrogen main source, mixed in sevenfold diluted seawater. At such conditions, several limitations of P. temperata bioinsecticide productions were shown to be overcome. The appearance of variants small colony polymorphism was completely avoided. Thus, the strain K122 was maintained at the primary form even after prolonged incubation. Moreover, the viable but nonculturable state was partially overcome, since the ability of P. temperata cells to form colonies on the solid medium was prolonged until 78 h of incubation. In addition, when cultured in the complex medium, P. temperata cells were produced at high cell density of 12 × 10(8) cells/ml and exhibited 81.48% improvement of oral toxicity compared to those produced in the optimized medium. With such medium, the large-scale bioinsecticides production into 3-l fully controlled fermenter improved the total cell counts, CFU counts and oral toxicity by 20, 5.81 and 16.73%, respectively. This should contribute to a significant reduction of production cost of highly potent P. temperata strain K122 cells, useful as a bioinsecticide.

  4. Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys

    PubMed Central

    Henry, Porche’ Kirkland; Davis, Michael

    2009-01-01

    Rationale The transition from infrequent and controlled cocaine use to dependence may involve enduring changes in neurobiology as a consequence of persistent drug use. Objective The present study utilized an intravenous drug self-administration protocol of increasing cocaine access to evaluate potential changes in dopamine function in vivo, including changes in sensitivity to psychostimulants. Materials and methods Drug-naïve rhesus monkeys were provided limited access (1 h) to cocaine self-administration for 60 days followed by 60 days under an extended access condition (4 h). Basal levels of striatal extracellular dopamine and its metabolites, as well as the effectiveness of cocaine and amphetamine to elevate dopamine, were determined with in vivo microdialysis before the initiation of cocaine self-administration and during limited and extended access. The effect of cocaine and amphetamine on the acoustic startle response was also examined to assess complementary behavioral changes as a function of drug history. Results Extended access to cocaine self-administration lead to increased daily intake compared to limited access conditions but did not result in escalated intake over time. However, cocaine- and amphetamine-induced increases in striatal dopamine were diminished as a function of cocaine self-administration history. Surprisingly, there was no effect of drug-taking history on sensitivity to psychostimulant-induced enhancement of startle amplitude. Conclusions The present experiments provide evidence of a hypofunctional dopamine system that is not associated with an escalation in drug intake or reflected in measures of acoustic startle. PMID:19365621

  5. Food Assistance: Financial Information on WIC Nutrition Services and Administrative Costs. United States General Accounting Office Report to Congressional Committees.

    ERIC Educational Resources Information Center

    Robertson, Robert E.

    The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a federally funded nutrition assistance program administered by the Department of Agriculture's (USDA) Food and Nutrition Service (FNS). Responding to Congressional requests for information regarding program costs, this report provides information on: (1) funding…

  6. Prevalence and Costs of Multimorbidity by Deprivation Levels in the Basque Country: A Population Based Study Using Health Administrative Databases

    PubMed Central

    Orueta, Juan F.; García-Álvarez, Arturo; García-Goñi, Manuel; Paolucci, Francesco; Nuño-Solinís, Roberto

    2014-01-01

    Background Multimorbidity is a major challenge for healthcare systems. However, currently, its magnitude and impact in healthcare expenditures is still mostly unknown. Objective To present an overview of the prevalence and costs of multimorbidity by socioeconomic levels in the whole Basque population. Methods We develop a cross-sectional analysis that includes all the inhabitants of the Basque Country (N = 2,262,698). We utilize data from primary health care electronic medical records, hospital admissions, and outpatient care databases, corresponding to a 4 year period. Multimorbidity was defined as the presence of two or more chronic diseases out of a list of 52 of the most important and common chronic conditions given in the literature. We also use socioeconomic and demographic variables such as age, sex, individual healthcare cost, and deprivation level. Predicted adjusted costs were obtained by log-gamma regression models. Results Multimorbidity of chronic diseases was found among 23.61% of the total Basque population and among 66.13% of those older than 65 years. Multimorbid patients account for 63.55% of total healthcare expenditures. Prevalence of multimorbidity is higher in the most deprived areas for all age and sex groups. The annual cost of healthcare per patient generated for any chronic disease depends on the number of coexisting comorbidities, and varies from 637 € for the first pathology in average to 1,657 € for the ninth one. Conclusion Multimorbidity is very common for the Basque population and its prevalence rises in age, and unfavourable socioeconomic environment. The costs of care for chronic patients with several conditions cannot be described as the sum of their individual pathologies in average. They usually increase dramatically according to the number of comorbidities. Given the ageing population, multimorbidity and its consequences should be taken into account in healthcare policy, the organization of care and medical research

  7. Medicare program; schedules of limits and prospectively determined payment rates for skilled nursing facility inpatient routine service costs--HCFA. Final notice with comment period.

    PubMed

    1997-10-01

    This final notice with comment period sets forth an updated schedule of limits on skilled nursing facility (SNF) routine service costs for which payment may be made under the Medicare program and sets forth an updated schedule of payment rates for low Medicare volume SNFs that elect to receive prospectively determined payment rates for routine service costs. Section 1888(a) of the Social Security Act (the Act) requires that the Secretary update the per diem cost limits for SNF routine service costs for cost reporting periods beginning on or after October 1, 1995, and every 2 years thereafter. In addition, section 1888(d)(4) of the Act requires the Secretary to establish and publish prospectively determined payment rates at least 90 days prior to the beginning of the Federal fiscal year (FY) to which such rates are to be applied.

  8. 43 CFR 12.62 - Allowable costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Allowable costs. 12.62 Section 12.62... COST PRINCIPLES FOR ASSISTANCE PROGRAMS Uniform Administrative Requirements for Grants and Cooperative Agreements to State and Local Governments Post-Award Requirements § 12.62 Allowable costs. (a) Limitation...

  9. 7 CFR 3016.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Allowable costs. 3016.22 Section 3016.22 Agriculture... GOVERNMENTS Post-Award Requirements Financial Administration § 3016.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees...

  10. 24 CFR 85.22 - Allowable costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Allowable costs. 85.22 Section 85... TRIBAL GOVERNMENTS Post-Award Requirements Financial Administration § 85.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the...

  11. 24 CFR 85.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Allowable costs. 85.22 Section 85... TRIBAL GOVERNMENTS Post-Award Requirements Financial Administration § 85.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the...

  12. 36 CFR 1207.22 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Allowable costs. 1207.22... GOVERNMENTS Post-Award Requirements Financial Administration § 1207.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1) The allowable costs of the grantees, subgrantees...

  13. 77 FR 19619 - Notice of Extension of Time Limit for the Preliminary Results of Administrative Review of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... Administrative Review of the Suspension Agreement on Hot-Rolled Flat- Rolled Carbon-Quality Steel Products from... Review of the Suspension Agreement on Hot-Rolled Flat-Rolled Carbon-Quality Steel Products from the... Investigation on Hot-Rolled Flat-Rolled Carbon-Quality Steel Products from the Russian Federation (the...

  14. 38 CFR 17.121 - Limitations on payment or reimbursement of the costs of emergency hospital care and medical...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... reimbursement of the costs of emergency hospital care and medical services not previously authorized. 17.121... reimbursement of the costs of emergency hospital care and medical services not previously authorized. Claims for payment or reimbursement of the costs of emergency hospital care or medical services not...

  15. 38 CFR 17.121 - Limitations on payment or reimbursement of the costs of emergency hospital care and medical...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... reimbursement of the costs of emergency hospital care and medical services not previously authorized. 17.121... reimbursement of the costs of emergency hospital care and medical services not previously authorized. Claims for payment or reimbursement of the costs of emergency hospital care or medical services not...

  16. When it is costly to have a caring mother: food limitation erases the benefits of parental care in earwigs.

    PubMed

    Meunier, Joël; Kölliker, Mathias

    2012-08-23

    The aggregation of parents with offspring is generally associated with different forms of care that improve offspring survival at potential costs to parents. Under poor environments, the limited amount of resources available can increase the level of competition among family members and consequently lead to adaptive changes in parental investment. However, it remains unclear as to what extent such changes modify offspring fitness, particularly when offspring can survive without parents such as in the European earwig, Forficula auricularia. Here, we show that under food restriction, earwig maternal presence decreased offspring survival until adulthood by 43 per cent. This effect was independent of sibling competition and was expressed after separation from the female, indicating lasting detrimental effects. The reduced benefits of maternal presence on offspring survival were not associated with higher investment in future reproduction, suggesting a condition-dependent effect of food restriction on mothers and local mother-offspring competition for food. Overall, these findings demonstrate for the first time a long-term negative effect of maternal presence on offspring survival in a species with maternal care, and highlight the importance of food availability in the early evolution of family life.

  17. Light for nurses' work in the 21st century: a review of lighting, human vision limitations, and medication administration.

    PubMed

    Graves, Krisanne; Symes, Lene; Cesario, Sandra K

    2014-01-01

    A literature review was conducted to determine the state of the science related to medication errors and light. The limited literature is discussed in relationship to human vision and light needs. Little systematic action has been taken to increase nurses' awareness of the connection between lighting and potential medication errors. Implications for nursing practice and research about light conditions are provided. Interventions from other industries may aid nursing in making decisions about light conditions.

  18. Detection limits and cost comparisons of human- and gull-associated conventional and quantitative PCR assays in artificial and environmental waters

    USGS Publications Warehouse

    Riedel, Timothy E.; Zimmer-Faust, Amity G.; Thulsiraj, Vanessa; Madi, Tania; Hanley, Kaitlyn T.; Ebentier, Darcy L.; Byappanahalli, Muruleedhara N.; Layton, Blythe; Raith, Meredith; Boehm, Alexandria B.; Griffith, John F.; Holden, Patricia A.; Shanks, Orin C.; Weisberg, Stephen B.; Jay, Jennifer A.

    2014-01-01

    Some molecular methods for tracking fecal pollution in environmental waters have both PCR and quantitative PCR (qPCR) assays available for use. To assist managers in deciding whether to implement newer qPCR techniques in routine monitoring programs, we compared detection limits (LODs) and costs of PCR and qPCR assays with identical targets that are relevant to beach water quality assessment. For human-associated assays targeting Bacteroidales HF183 genetic marker, qPCR LODs were 70 times lower and there was no effect of target matrix (artificial freshwater, environmental creek water, and environmental marine water) on PCR or qPCR LODs. The PCR startup and annual costs were the lowest, while the per reaction cost was 62% lower than the Taqman based qPCR and 180% higher than the SYBR based qPCR. For gull-associated assays, there was no significant difference between PCR and qPCR LODs, target matrix did not effect PCR or qPCR LODs, and PCR startup, annual, and per reaction costs were lower. Upgrading to qPCR involves greater startup and annual costs, but this increase may be justified in the case of the human-associated assays with lower detection limits and reduced cost per sample.

  19. Detection limits and cost comparisons of human- and gull-associated conventional and quantitative PCR assays in artificial and environmental waters.

    PubMed

    Riedel, Timothy E; Zimmer-Faust, Amity G; Thulsiraj, Vanessa; Madi, Tania; Hanley, Kaitlyn T; Ebentier, Darcy L; Byappanahalli, Muruleedhara; Layton, Blythe; Raith, Meredith; Boehm, Alexandria B; Griffith, John F; Holden, Patricia A; Shanks, Orin C; Weisberg, Stephen B; Jay, Jennifer A

    2014-04-01

    Some molecular methods for tracking fecal pollution in environmental waters have both PCR and quantitative PCR (qPCR) assays available for use. To assist managers in deciding whether to implement newer qPCR techniques in routine monitoring programs, we compared detection limits (LODs) and costs of PCR and qPCR assays with identical targets that are relevant to beach water quality assessment. For human-associated assays targeting Bacteroidales HF183 genetic marker, qPCR LODs were 70 times lower and there was no effect of target matrix (artificial freshwater, environmental creek water, and environmental marine water) on PCR or qPCR LODs. The PCR startup and annual costs were the lowest, while the per reaction cost was 62% lower than the Taqman based qPCR and 180% higher than the SYBR based qPCR. For gull-associated assays, there was no significant difference between PCR and qPCR LODs, target matrix did not effect PCR or qPCR LODs, and PCR startup, annual, and per reaction costs were lower. Upgrading to qPCR involves greater startup and annual costs, but this increase may be justified in the case of the human-associated assays with lower detection limits and reduced cost per sample.

  20. Clinical consequences and cost of limiting use of vancomycin for perioperative prophylaxis: example of coronary artery bypass surgery.

    PubMed Central

    Zanetti, G.; Goldie, S. J.; Platt, R.

    2001-01-01

    Routine us of vancomycin for perioperative prophylaxis is discouraged, principally to minimize microbial resistance to it. However, outcomes and costs of this recommendation have not been assessed. We used decision-analytic models to compare clinical results and cost-effectiveness of no prophylaxis, cefazolin, and vancomycin, in coronary artery bypass graft surgery. In the base case, vancomycin resulted in 7% fewer surgical site infections and 1% lower all-cause mortality and saved $117 per procedure, compared with cefazolin. Cefazolin, in turn, resulted in substantially fewer infections and deaths and lower costs than no prophylaxis. We conclude that perioperative antibiotic prophylaxis with vancomycin is usually more effective and less expensive than cefazolin. Data on vancomycin's impact on resistance are needed to quantify the trade-off between individual patients' improved clinical outcomes and lower costs and the future long-term consequences to society. PMID:11747694

  1. Medicare program; reissuance of the wage index in the 1981 schedule of limits on hospital per diem inpatient general routine operating costs--HCFA. Final notice.

    PubMed

    1984-11-26

    This notice affirms the use of the wage index that was used to calculate the 1981 schedule of limits on hospital per diem inpatient general routine operating costs, which was issued on June 30, 1981 [46 FR 33637], and September 30, 1981 [46 FR 48010]. The 1981 wage index was reissued for public comment on February 17, 1984 [49 FR 6175].

  2. Achieving the Health Care Financing Administration limits by quality improvement and quality control. A real-world example.

    PubMed

    Engebretson, M J; Cembrowski, G S

    1992-07-01

    With the enactment of the Clinical Laboratory Improvement Amendments of 1988 (CLIA 88), the federal government is now using proficiency testing as the primary indicator of laboratory quality. Laboratories with proficiency test failures are now at risk of a variety of harsh penalties including large monetary fines and suspension of operations. To minimize the risk of failed proficiency testing, we initiated a continuous quality improvement program in our general chemistry laboratory in conjunction with the use of a new survey-validated quality control product. This article describes the quality improvement program and our success in reducing the long-term random error in general chemistry. Despite our improvement program, significant analytical errors (greater than 30% of the CLIA limits) still exist in analytes measured by our chemistry analyzer. These errors are present in nearly the same analytes measured by other common chemistry analyzers indicating the need for improvement in their design and manufacture.

  3. Investigation of truck size and weight limits: technical supplement volume 7. carrier, market and regional cost and energy tradeoffs, part i. Final report oct 78-oct 81

    SciTech Connect

    Maio, D.J.

    1982-10-01

    This volume expands upon the summary results in the Secretary's Report to Congress and provides a more comprehensive treatment of the productivity and fuel tradeoffs among the categories of truck size, weight and configuration limits. Disaggregations of impacts among freight service user groups are reported to provide information to the interest groups most affected by alternative limit changes. It also presents an analysis of the sensitivity of the reported transport cost and fuel impacts of alternative limits to the possible inaccuracies in the analytical methods and data available to the study.

  4. The Impact of the US Food and Drug Administration Chlorofluorocarbon Ban on Out-of-pocket Costs and Use of Albuterol Inhalers Among Individuals With Asthma

    PubMed Central

    Jena, Anupam B.; Ho, Oliver; Goldman, Dana P.; Karaca-Mandic, Pinar

    2015-01-01

    IMPORTANCE The US Clean Air Act prohibits use of nonessential ozone-depleting substances. In 2005, the US Food and Drug Administration announced the ban of chlorofluorocarbon (CFC) albuterol inhalers by December 31, 2008. The policy resulted in the controversial replacement of generic CFC inhalers by more expensive, branded hydrofluoroalkane inhalers. The policy’s impact on out-of-pocket costs and utilization of albuterol is unknown. OBJECTIVE To study the impact of the US Food and Drug Administration’s CFC ban on out-of-pocket costs and utilization of albuterol inhalers. DESIGN, SETTING, AND PARTICIPANTS Using private insurance data from January 1, 2004, to December 31, 2010, we investigated the effect of the CFC ban on out-of-pocket costs and utilization of albuterol inhalers among individuals with asthma (109 428 adults; 37 281 children), as well as asthma-related hospitalizations, emergency department visits, and outpatient visits. We estimated multivariable models adjusted for age, sex, comorbidities, and mean out-of-pocket costs of albuterol inhalers in an individual’s drug plan. We analyzed whether effects varied between adults vs children and those with persistent vs nonpersistent asthma. MAIN OUTCOMES AND MEASURES Pharmacy claims for albuterol inhalers, as well as asthma-related hospitalizations, emergency department visits, and outpatient visits. RESULTS The mean out-of-pocket albuterol cost rose from $13.60 (95% CI, $13.40–$13.70) per prescription in 2004 to $25.00 (95% CI, $24.80–$25.20) immediately after the 2008 ban. By the end of 2010, costs had lowered to $21.00 (95% CI, $20.80–$21.20) per prescription. Overall albuterol inhaler use steadily declined from 2004 to 2010. Steep declines in use of generic CFC inhalers occurred after the fourth quarter of 2006 and were almost fully offset by increases in use of hydrofluoroalkane inhalers. In multivariable analyses, a $10 increase in out-of-pocket albuterol prescription costs was estimated to

  5. 38 CFR 17.121 - Limitations on payment or reimbursement of the costs of emergency treatment not previously...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... VA has an agreement with to furnish health care services for veterans), which means the non-VA... emergency treatment: (1) Could have been transferred from the non-VA facility to a VA medical center (or...) Continued non-emergency treatment. Claims for payment or reimbursement of the costs of emergency...

  6. 38 CFR 17.121 - Limitations on payment or reimbursement of the costs of emergency treatment not previously...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... VA has an agreement with to furnish health care services for veterans), which means the non-VA... emergency treatment: (1) Could have been transferred from the non-VA facility to a VA medical center (or...) Continued non-emergency treatment. Claims for payment or reimbursement of the costs of emergency...

  7. 10 CFR 600.222 - Allowable costs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Allowable costs. 600.222 Section 600.222 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....222 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1)...

  8. 10 CFR 600.222 - Allowable costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Allowable costs. 600.222 Section 600.222 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....222 Allowable costs. (a) Limitation on use of funds. Grant funds may be used only for: (1)...

  9. Accuracy of a Low-Cost Novel Computer-Vision Dynamic Movement Assessment: Potential Limitations and Future Directions

    NASA Astrophysics Data System (ADS)

    McGroarty, M.; Giblin, S.; Meldrum, D.; Wetterling, F.

    2016-04-01

    The aim of the study was to perform a preliminary validation of a low cost markerless motion capture system (CAPTURE) against an industry gold standard (Vicon). Measurements of knee valgus and flexion during the performance of a countermovement jump (CMJ) between CAPTURE and Vicon were compared. After correction algorithms were applied to the raw CAPTURE data acceptable levels of accuracy and precision were achieved. The knee flexion angle measured for three trials using Capture deviated by -3.8° ± 3° (left) and 1.7° ± 2.8° (right) compared to Vicon. The findings suggest that low-cost markerless motion capture has potential to provide an objective method for assessing lower limb jump and landing mechanics in an applied sports setting. Furthermore, the outcome of the study warrants the need for future research to examine more fully the potential implications of the use of low-cost markerless motion capture in the evaluation of dynamic movement for injury prevention.

  10. Narrowing Limits of Administrative Discretion.

    ERIC Educational Resources Information Center

    Richardson, Jr., Richard C.; Johnson, Edward

    1980-01-01

    This review of court cases and statutes focuses on the impact of the first and fourteenth amendments and antidiscrimination legislation. Three recommendations are made: (1) The need for liability insurance is evident; (2) Every college and university should retain its own legal council; and (3) Institutions with collective bargaining should employ…

  11. Cost-effectiveness of chemotherapy combined with thoracic radiotherapy versus chemotherapy alone for limited stage small cell lung cancer: A population-based propensity-score matched analysis

    PubMed Central

    Chien, Chun-Ru; Hsia, Te-Chun; Chen, Chih-Yi

    2014-01-01

    Background The addition of thoracic radiotherapy improves the outcome of limited stage small cell lung cancer (LS-SCLC), however, the cost-effectiveness of this process has never been reported. We aimed to estimate the short-term cost-effectiveness of chemotherapy combined with thoracic radiotherapy (C-TRT) versus chemotherapy alone (C/T) for LS-SCLC patients from the payer's perspective (Taiwan National Health Insurance). Methods We identified LS-SCLC patients diagnosed within 2007–2009 through a comprehensive population-based database containing cancer and death registries, and reimbursement data. The duration of interest was one year within diagnosis. We included potential confounding covariables through literature searching and our own experience, and used a propensity score to construct a 1:1 population for adjustment. We used a net benefit (NB) approach to evaluate the cost-effectiveness at various willingness-to-pay (WTP) levels. Sensitivity analysis regarding potential unmeasured confounder(s) was performed. Results Our study population constituted 74 patients. The mean cost (2013 USD) and survival (year) was higher for C-TRT (42 439 vs. 28 357; 0.94 vs. 0.88). At the common WTP level (50 000 USD/life-year), C-TRT was not cost effective (incremental NB − 11 082) and the probability for C-TRT to be cost effective (i.e. positive net benefit) was 0.005. The result was moderately sensitive to potential unmeasured confounder(s) in sensitivity analysis. Conclusions We provide evidence that when compared to C/T, C-TRT is effective in improving survival, but is not cost-effective in the short-term at a common WTP level from a payer's perspective. This information should be considered by clinicians when discussing thoracic radiotherapy with their LS-SCLC patients. PMID:26767048

  12. A simplified, cost- and time-effective procedure for genotyping pearl millet in resource-limited laboratories

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Procedures for DNA extraction and genotyping of large plant populations are cumbersome and expensive for resource-limited laboratories. Through eliminating or changing several steps used in DNA extraction, PCR amplification and PAGE electrophoresis in pearl millet [Pennisetum glaucum (L.) R. Br.], w...

  13. Extended-access, but not limited-access, methamphetamine self-administration induces behavioral and nucleus accumbens dopamine response changes in rats.

    PubMed

    Le Cozannet, Romain; Markou, Athina; Kuczenski, Ronald

    2013-11-01

    To better understand the neurobiology of methamphetamine (METH) dependence and the cognitive impairments induced by METH use, we compared the effects of extended (12 h) and limited (1 h) access to METH self-administration on locomotor activity and object place recognition, and on extracellular dopamine levels in the nucleus accumbens and caudate-putamen. Rats were trained to self-administer intravenous METH (0.05 mg/kg). One group had progressively extended access up to 12-h sessions. The other group had limited-access 1-h sessions. Microdialysis experiments were conducted during a 12-h and 1-h session, in which the effects of a single METH injection (self-administered, 0.05 mg/kg, i.v.) on extracellular dopamine levels were assessed in the nucleus accumbens and caudate-putamen compared with a drug-naive group. The day after the last 12-h session and the following day experimental groups were assessed for their locomotor activities and in a place recognition procedure, respectively. The microdialysis results revealed tolerance to the METH-induced increases in extracellular dopamine only in the nucleus accumbens, but not in the caudate-putamen in the extended-access group compared with the control and limited-access groups. These effects may be associated with the increased lever-pressing and drug-seeking observed during the first hour of drug exposure in the extended-access group. This increase in drug-seeking leads to higher METH intake and may result in more severe consequences in other structures responsible for the behavioral deficits (memory and locomotor activity) observed in the extended-access group, but not in the limited-access group.

  14. National Democratic Institute Grant’s Security Costs and Impact Generally Supported, but Department of State Oversight Limited

    DTIC Science & Technology

    2010-10-13

    impact of all of its work in meeting grant goals and objectives. DRL noted that it continues to take steps to improve monitoring and evaluation we...and objectives. DRL noted that it continues to take steps to improve monitoring and evaluation . For example, it is requiring more comprehensive...among other things, demonstrated contributions from these meetings. Limited Monitoring and Evaluation Plan Contributed to Problems in Assessing

  15. Transmission line capital costs

    SciTech Connect

    Hughes, K.R.; Brown, D.R.

    1995-05-01

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy`s Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs.

  16. Secondary Measures of Access to Abortion Services in the United States, 2011 and 2012: Gestational Age Limits, Cost, and Harassment

    PubMed Central

    Jerman, Jenna; Jones, Rachel K.

    2016-01-01

    Background Aspects of U.S. clinical abortion service provision such as gestational age limits, charges for abortion services, and anti-abortion harassment can impact the accessibility of abortion; this study documents changes in these measures between 2008 and 2012. Methods In 2012 and 2013, we surveyed all known abortion-providing facilities in the United States (n = 1,720). This study summarizes information obtained about gestational age limits, charges, and exposure to anti-abortion harassment among clinics; response rates for relevant items ranged from 54% (gestational limits) to 80% (exposure to harassment). Weights were constructed to compensate for nonresponding facilities. We also examine the distribution of abortions and abortion facilities by region. Findings Almost all abortion facilities (95%) offered abortions at 8 weeks’ gestation; 72% did so at 12 weeks, 34% at 20 weeks, and 16% at 24 weeks in 2012. In 2011 and 2012, the median charge for a surgical abortion at 10 weeks gestation was $495, and $500 for an early medication abortion, compared with $503 and $524 (adjusted for inflation) in 2009. In 2011, 84% of clinics experienced at least one form of harassment, only slightly higher than found in 2009. Hospitals and physicians’ offices accounted for a substantially smaller proportion of facilities in the Midwest and South. Clinics in the Midwest and South were exposed to more harassment than their counterparts in the Northeast and West. Conclusions Although there was a substantial decline in abortion incidence between 2008 and 2011, the secondary measures of abortion access examined in this study changed little during this time period. PMID:24981401

  17. Genotype assays and third-line ART in resource-limited settings: A simulation and cost-effectiveness analysis of a planned clinical trial

    PubMed Central

    Lorenzana, Sarah B.; Hughes, Michael D.; Grinsztejn, Beatriz; Collier, Ann C.; Luz, Paula Mendes; Freedberg, Kenneth A.; Wood, Robin; Levison, Julie H.; Mugyenyi, Peter N.; Salata, Robert; Wallis, Carole L.; Weinstein, Milton C.; Schooley, Robert T.; Walensky, Rochelle P.

    2012-01-01

    Objectives To project the clinical and economic outcomes of a genotype assay for selection of third-line antiretroviral therapy (ART) in resource-limited settings, as per the planned international A5288 trial (MULTI-OCTAVE). Methods We used the Cost-effectiveness of Preventing AIDS Complications (CEPAC)-International Model to compare three strategies for subjects who have failed second-line ART in South Africa: (1) Sustained second-line: no genotype assay, all subjects remain on second-line ART; (2) A5288: genotype to determine the resistance profile and assign an appropriate regimen; or (3) Population-based third-line: no genotype, all subjects switch to a potent third-line regimen. Model inputs are from published data in South Africa. Resistance profiles, ART regimens, and efficacy data were those used for trial planning. Results Projected life expectancy for sustained second-line, A5288, and population-based third-line are 61.1, 103.8, and 104.2 months. Compared to sustained second-line ($12,460), per person lifetime costs increase for the A5288 ($39,250) and population-based ($44,120) strategies. The incremental cost-effectiveness ratio of A5288, compared to sustained second-line, is $7,500/year of life saved (YLS), and for population-based third-line, compared to A5288, is $154,500/YLS. In the A5288 strategy, very late presentation to care, coupled with lengthy delays to obtain the genotype, dramatically reduces 5-yr survival, making the population-based third-line strategy more attractive. Conclusions We project that, while the public health approach to third-line therapy is unaffordable, genotype assays and third-line ART in resource-limited settings will increase survival and be cost-effective compared to the population-based approach, supporting the value of an efficacy study. PMID:22343964

  18. 46 CFR 298.21 - Limits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Limits. 298.21 Section 298.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VESSEL FINANCING ASSISTANCE OBLIGATION GUARANTEES Guarantees § 298.21 Limits. (a) Actual Cost basis. We will issue a guarantee on an amount of the...

  19. In vivo effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract

    PubMed Central

    Fang, Zhong-Ze; Krausz, Kristopher W; Nagaoka, Kenjiro; Tanaka, Naoki; Gowda, Krishne; Amin, Shantu G; Perdew, Gary H; Gonzalez, Frank J

    2014-01-01

    Background and Purpose GNF-351 is a potent aryl hydrocarbon receptor (AHR) antagonist that inhibits dioxin response element-dependent and independent activities. Here, the absorption, metabolism and in vivo AHR antagonist activity of GNF-351 were investigated. Experimental Approach LC-MS metabolomics was used to analyse GNF-351 metabolism in vitro and in vivo. Recombinant drug-metabolizing enzymes were employed to determine the enzymes involved in GNF-351 metabolism. Analysis of target AHR genes was performed to investigate the inhibitory effects of GNF-351 towards AHR activation. Key Results Several phase I metabolites were generated after GNF-351 was incubated with microsomes from human or mouse liver and intestine, including two oxidized GNF-351 and one tri-demethylated GNF-351. Poor absorption from the intestine resulted in no detectable levels of GNF-351 in mouse serum (0–6 h) and urine (24 h) and almost all GNF-351 was found in the faeces after 24 h. Analysis of faeces further revealed all the in vitro phase I metabolites. Novel metabolites were detected, including one di-oxidized GNF-351, two oxidized and tri-demethylated GNF-351, one dehydrogenated product of oxidized GNF-351, and one sulfation product of di-oxidized GNF-351. Cytochromes P450 were demonstrated to be the major enzymes involved in metabolism of GNF-351. After oral administration to mice, GNF-351 readily inhibited β-naphthoflavone-induced AHR activation in ileum and colon, but not that in the liver. Conclusion and Implications While poor absorption and extensive metabolism after oral administration limited the in vivo effects of the pure AHR antagonist GNF-351 in liver, it could be used to inhibit AHR activation in intestine and colon. PMID:24417285

  20. Using cost-benefit analysis and social return on investment to evaluate the impact of social enterprise: Promises, implementation, and limitations.

    PubMed

    Cordes, Joseph J

    2016-11-21

    Since the early 2000's there has been growing interest in using the Social Return on Investment (SROI) as a measure for assessing the performance of social enterprises. By analogy with its business counterpart, the Return on Investment (ROI), the SROI is a metric that compares the monetized social costs of a program with the monetized social benefits of achieving an outcome (or set of outcomes). For example, calculating the SROI of a nonprofit half-way house for drug addicts might involve estimating the reduced social costs attributable to successful rehabilitation of addicts, and comparing this to the social costs of operating the half-way house. Alternatively, the total return of a for-profit social enterprise providing affordable housing might consist both of the traditional private return on investment along with the economic value of meeting the housing needs of lower income households. Early descriptions of the methodology for calculating the SROI suggest that the approach initially evolved from standard methodologies found in the business finance literature for evaluating investments, with the important twist that nonprofit sector returns/payoffs are defined in broader social terms (Thornley, Anderson, & Dixon, 2016). Yet, someone who is familiar with the economic literature on cost benefit analysis (CBA) as it is applied to the evaluation of public programs cannot help but be struck by the similarity between the outcomes that CBA is intended to measure, and those that are the object of efforts to calculate the SROI. One implication is that the literature on the theory and practice of cost benefit analysis offers useful lessons about how to measure the social return on investment, as well as about potential caveats and limitations that need to be confronted when attempting to undertake an analysis of the SROI. The paper discusses the potential uses and limitations of CBA and SROI as tools that governments, private donor/investors, and foundations can use to

  1. Effect of model error on precipitation forecasts in the high-resolution limited area ensemble prediction system of the Korea Meteorological Administration

    NASA Astrophysics Data System (ADS)

    Kim, SeHyun; Kim, Hyun Mee

    2015-04-01

    In numerical weather prediction using convective-scale model resolution, forecast uncertainties are caused by initial condition error, boundary condition error, and model error. Because convective-scale forecasts are influenced by subgrid scale processes which cannot be resolved easily, the model error becomes more important than the initial and boundary condition errors. To consider the model error, multi-model and multi-physics methods use several models and physics schemes and the stochastic physics method uses random numbers to create a noise term in the model equations (e.g. Stochastic Perturbed Parameterization Tendency (SPPT), Stochastic Kinetic Energy Backscatter (SKEB), Stochastic Convective Vorticity (SCV), and Random Parameters (RP)). In this study, the RP method was used to consider the model error in the high-resolution limited area ensemble prediction system (EPS) of the Korea Meteorological Administration (KMA). The EPS has 12 ensemble members with 3 km horizontal resolution which generate 48 h forecasts. The initial and boundary conditions were provided by the global EPS of the KMA. The RP method was applied to microphysics and boundary layer schemes, and the ensemble forecasts using RP were compared with those without RP during July 2013. Both Root Mean Square Error (RMSE) and spread of wind at 10 m verified by surface Automatic Weather System (AWS) observations decreased when using RP. However, for 1 hour accumulated precipitation, the spread increased with RP and Equitable Threat Score (ETS) showed different results for each rainfall event.

  2. 45 CFR 263.13 - Is there a limit on the amount of Federal TANF funds that a State may spend on administrative costs?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., support or operate the portions of information technology or computer systems used for tracking and... those portions of information technology or computer systems used for tracking or monitoring. ...) Expenditures on the information technology and computerization needed for tracking and monitoring required...

  3. 45 CFR 263.13 - Is there a limit on the amount of Federal TANF funds that a State may spend on administrative costs?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., support or operate the portions of information technology or computer systems used for tracking and... those portions of information technology or computer systems used for tracking or monitoring. ...) Expenditures on the information technology and computerization needed for tracking and monitoring required...

  4. Melt-and-mold fabrication (MnM-Fab) of reconfigurable low-cost devices for use in resource-limited settings.

    PubMed

    Li, Zhi; Tevis, Ian D; Oyola-Reynoso, Stephanie; Newcomb, Lucas B; Halbertsma-Black, Julian; Bloch, Jean-Francis; Thuo, Martin

    2015-12-01

    Interest in low-cost analytical devices (especially for diagnostics) has recently increased; however, concomitant translation to the field has been slow, in part due to personnel and supply-chain challenges in resource-limited settings. Overcoming some of these challenges require the development of a method that takes advantage of locally available resources and/or skills. We report a Melt-and-mold fabrication (MnM Fab) approach to low-cost and simple devices that has the potential to be adapted locally since it requires a single material that is recyclable and simple skills to access multiple devices. We demonstrated this potential by fabricating entry level bio-analytical devices using an affordable low-melting metal alloy, Field's metal, with molds produced from known materials such as plastic (acrylonitrile-butadiene-styrene (ABS)), glass, and paper. We fabricated optical gratings then 4×4 well plates using the same recycled piece of metal. We then reconfigured the well plates into rapid prototype microfluidic devices with which we demonstrated laminar flow, droplet generation, and bubble formation from T-shaped channels. We conclude that this MnM-Fab method is capable of addressing some challenges typically encountered with device translation, such as technical know-how or material supply, and that it can be applied to other devices, as needed in the field, using a single moldable material.

  5. Nasal oxytocin administration reduces food intake without affecting locomotor activity and glycemia with c-Fos induction in limited brain areas.

    PubMed

    Maejima, Yuko; Rita, Rauza Sukma; Santoso, Putra; Aoyama, Masato; Hiraoka, Yuichi; Nishimori, Katsuhiko; Gantulga, Darambazar; Shimomura, Kenju; Yada, Toshihiko

    2015-01-01

    Recent studies have considered oxytocin (Oxt) as a possible medicine to treat obesity and hyperphagia. To find the effective and safe route for Oxt treatment, we compared the effects of its nasal and intraperitoneal (IP) administration on food intake, locomotor activity, and glucose tolerance in mice. Nasal Oxt administration decreased food intake without altering locomotor activity and increased the number of c-Fos-immunoreactive (ir) neurons in the paraventricular nucleus (PVN) of the hypothalamus, the area postrema (AP), and the dorsal motor nucleus of vagus (DMNV) of the medulla. IP Oxt administration decreased food intake and locomotor activity and increased the number of c-Fos-ir neurons not only in the PVN, AP, and DMNV but also in the nucleus of solitary tract of the medulla and in the arcuate nucleus of the hypothalamus. In IP glucose tolerance tests, IP Oxt injection attenuated the rise of blood glucose, whereas neither nasal nor intracerebroventricular Oxt affected blood glucose. In isolated islets, Oxt administration potentiated glucose-induced insulin secretion. These results indicate that both nasal and IP Oxt injections reduce food intake to a similar extent and increase the number of c-Fos-ir neurons in common brain regions. IP Oxt administration, in addition, activates broader brain regions, reduces locomotor activity, and affects glucose tolerance possibly by promoting insulin secretion from pancreatic islets. In comparison with IP administration, the nasal route of Oxt administration could exert a similar anorexigenic effect with a lesser effect on peripheral organs.

  6. Cost Control

    ERIC Educational Resources Information Center

    Foreman, Phillip

    2009-01-01

    Education administrators involved in construction initiatives unanimously agree that when it comes to change orders, less is more. Change orders have a negative rippling effect of driving up building costs and producing expensive project delays that often interfere with school operations and schedules. Some change orders are initiated by schools…

  7. Costs and cost containment in nursing homes.

    PubMed Central

    Smith, H L; Fottler, M D

    1981-01-01

    The study examines the impact of structural and process variables on the cost of nursing home care and the utilization of various cost containment methods in 43 california nursing homes. Several predictors were statistically significant in their relation to cost per patient day. A diverse range of cost containment techniques was discovered along with strong predictors of the utilization of these techniques by nursing home administrators. The trade-off between quality of care and cost of care is discussed. PMID:7228713

  8. Administrators: Nursing Home Administrator

    ERIC Educational Resources Information Center

    Kahl, Anne

    1976-01-01

    Responsibilities, skills needed, training needed, earnings, employment outlook, and sources of additional information are outlined for the administrator who holds the top management job in a nursing home. (JT)

  9. The Impact of Recent Federal Administrative Rules on Army Dental Care. Volume 1. A Cost Analysis of Bloodborne Pathogens: A Report of Consultation

    DTIC Science & Technology

    1992-12-31

    procedure codes 9973 and 9974), and the unit cost to the Fort Sam Houston DENTAC ($.79). Expenditures on dental handpieces were estimated using the guidance...handling procedure codes 9972, 9973 , and 9974 (3,417,985). Of that, 1,796,176 were related to treatment ( 9973 , 9974). 7 When the estimated annual cost...Maintaining Training Records 00 Secretary ( GS 5) - 20 hours/year @ $11.47 per hour = $229.40. For 40 DENTACs/ADLs, total = $9,476.00 e. DTR Preparation

  10. 36 CFR 1201.18 - What interest, penalty charges, and administrative costs will I have to pay on a debt owed to NARA?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What interest, penalty..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION GENERAL RULES COLLECTION OF... necessary to protect the interests of NARA or established by a contract, repayment agreement, or...

  11. 7 CFR Appendix A to Part 277 - Principles for Determining Costs Applicable to Administration of the Food Stamp Program by State...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... provides funds to carry out programs, services, or activities in connection with administration of the Food... activities and operations of the State agency which are necessary to carry out the purposes of the Food Stamp... include procurement, payroll, personnel functions, maintenance and operation of space, data...

  12. 7 CFR Appendix A to Part 277 - Principles for Determining Costs Applicable to Administration of the Food Stamp Program by State...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... provides funds to carry out programs, services, or activities in connection with administration of the Food... activities and operations of the State agency which are necessary to carry out the purposes of the Food Stamp... include procurement, payroll, personnel functions, maintenance and operation of space, data...

  13. 7 CFR Appendix A to Part 277 - Principles for Determining Costs Applicable to Administration of the Food Stamp Program by State...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provides funds to carry out programs, services, or activities in connection with administration of the Food... activities and operations of the State agency which are necessary to carry out the purposes of the Food Stamp... include procurement, payroll, personnel functions, maintenance and operation of space, data...

  14. 7 CFR Appendix A to Part 277 - Principles for Determining Costs Applicable to Administration of the Food Stamp Program by State...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... provides funds to carry out programs, services, or activities in connection with administration of the Food... activities and operations of the State agency which are necessary to carry out the purposes of the Food Stamp... include procurement, payroll, personnel functions, maintenance and operation of space, data...

  15. 7 CFR Appendix A to Part 277 - Principles for Determining Costs Applicable to Administration of the Food Stamp Program by State...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... provides funds to carry out programs, services, or activities in connection with administration of the Food... activities and operations of the State agency which are necessary to carry out the purposes of the Food Stamp... include procurement, payroll, personnel functions, maintenance and operation of space, data...

  16. 40 CFR 30.27 - Allowable costs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER...-Profit Organizations.” The allowability of costs incurred by institutions of higher education is..., however, pay consultants more than this amount.) This limitation applies to consultation services...

  17. Effects of introducing an administrative .05% blood alcohol concentration limit on law enforcement patterns and alcohol-related collisions in Canada.

    PubMed

    Blais, Étienne; Bellavance, François; Marcil, Alexandra; Carnis, Laurent

    2015-09-01

    Except for Quebec, all Canadian provinces have introduced administrative laws to lower the permitted blood alcohol concentration (BAC) to .05% or .04% for driving-or having the care of-a motor vehicle. Using linear mixed effects models for longitudinal data, this study evaluates the effect of administrative BAC laws on fatal alcohol related crashes and law enforcement patterns in Canada from 1987 to 2010. Results reveal a significant decrease of 3.7% (95% C.I.: 0.9-6.5%) in fatally injured drivers with a BAC level equal or greater than .05% following the introduction of these laws. Reductions were also observed for fatally injured drivers with BAC levels greater that .08% and .15%. The introduction of administrative BAC laws led neither to significant changes in the rate of driving while impaired (DWI) incidents reported by police officers nor in the probability of being charged for DWI under the Criminal Code.

  18. 78 FR 40696 - Proposed Information Collection; Comment Request; Alaska Crab Cost Recovery

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... Crab Cost Recovery AGENCY: National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION... and Aleutian Islands (BSAI) Crab includes the Crab Rationalization (CR) Program, a limited access system that allocates BSAI Crab resources among harvesters, processors, and coastal communities....

  19. Short Communication: A Low-Cost Method for Analyzing Nevirapine Levels in Hair as a Marker of Adherence in Resource-Limited Settings

    PubMed Central

    Yang, Qiyun; Bacchetti, Peter; Huang, Yong

    2014-01-01

    Abstract The measurement of antiretroviral concentrations in hair is emerging as an important technology to objectively quantify adherence to combination antiretroviral therapy. Hair levels of antiretrovirals are the strongest independent predictor of virologic success in large prospective cohorts of HIV-infected patients and surpass self-report in predicting outcomes. Hair is easy to collect and store, but validated methods to analyze antiretroviral levels in hair using liquid chromatography tandem mass spectrometry (LC-MS/MS) are expensive. We report here on the development of a thin-layer chromatography (TLC) assay for the semiquantitative analysis of nevirapine in hair. TLC assay results from 11 samples were consistent with results using LC-MS/MS [Spearman correlation coefficient 0.99 (95% CI 0.95–0.996)]. This simple, low-cost method of analyzing nevirapine concentrations in hair may provide a novel monitoring tool for antiretroviral adherence in resource-limited settings and merits further study in clinical settings. PMID:24164410

  20. Use of federal assistance for private-operator capital cost in UMTA's (Urban Mass Transportation Administration's) Entrepreneurial Services Challenge Grant Program

    SciTech Connect

    Not Available

    1988-03-01

    Dynamic changes in travel patterns stepped up the need for alternative transit service. The explosive growth of employment in the suburbs and the increasing number of city-to-suburb and inter-suburban trips have created 'new markets' that require more flexible and smaller-scale approaches than those provided by large centralized transit systems. UMTA has developed a program to respond to these 'new market' needs--The Entrepreneurial Services Challenge Grant Program (ESCGP). It features start-up capital costs support to entrepreneurs and supports the cost of a provider's own equipment purchase or lease (instead of UMTA buying vehicles and leasing or donating them to a provider). The idea behind the ESCGP is to help start new private transit services that can eventually operate without public subsidy. The program is directed toward two groups: equipment lessors and the entrepreneurial transit service providers. The report presents the ESCGP in detail and illustrates its application through case studies.

  1. Report: No Intent to Underestimate Costs Was Found, but Supporting Documentation for EPA’s Final Rule Limiting Sulfur in Gasoline Was Incomplete or Inaccurate in Several Instances

    EPA Pesticide Factsheets

    Report #16-P-0122, March 29, 2016. Inaccurate or incomplete documentation of the EPA's cost modeling could prevent a third party from obtaining a full and accurate understanding of how the EPA arrived at its cost estimate for the Tier 3 rule.

  2. 13 CFR 107.855 - Interest rate ceiling and limitations on fees charged to Small Businesses (“Cost of Money”).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... points. In either case, round the sum down to the nearest eighth of one percent. (3) If the result is... cash flows back to the first disbursement date using the Cost of Money ceiling from paragraph (d)...

  3. 13 CFR 107.855 - Interest rate ceiling and limitations on fees charged to Small Businesses (“Cost of Money”).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... points. In either case, round the sum down to the nearest eighth of one percent. (3) If the result is... cash flows back to the first disbursement date using the Cost of Money ceiling from paragraph (d)...

  4. 13 CFR 107.855 - Interest rate ceiling and limitations on fees charged to Small Businesses (“Cost of Money”).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... points. In either case, round the sum down to the nearest eighth of one percent. (3) If the result is... cash flows back to the first disbursement date using the Cost of Money ceiling from paragraph (d)...

  5. The application of EOQ and lead time crashing cost models in material with limited life time (Case study: CN-235 Aircraft at PT Dirgantara Indonesia)

    NASA Astrophysics Data System (ADS)

    Agustina Hidayat, Yosi; Ria Kasanah, Aprilia; Yudhistira, Titah

    2016-02-01

    PT. Dirgantara Indonesia, one of State Owned Enterprises engaging in the aerospace industry, targets to control 30% of world market for light and medium sized aircraft. One type of the aircrafts produced by PT. DI every year is CN-235. Currently, the cost of material procurement reaches 50% of the total cost of production. Material has a variety of characteristics, one of which is having a lifetime. The demand characteristic of the material with expiration for the CN-235 aircraft is deterministic. PT DI does not have any scientific background for its procurement of raw material policy. In addition, there are two methods of transportation used for delivering materials, i.e. by land and air. Each method has different lead time. Inventory policies used in this research are deterministic and probabilistic. Both deterministic and probabilistic single and multi-item inventory policies have order quantity, time to order, reorder point, and lead time as decision variables. The performance indicator for this research is total inventory cost. Inventory policy using the single item EOQ and considering expiration factor inventory results in a reduction in total costs up to 69.58% and multi item results in a decrease in total costs amounted to 71.16%. Inventory policy proposal using the model of a single item by considering expiration factor and lead time crashing cost results in a decrease in total costs amounted to 71.5% and multi item results in a decrease in total costs amounted to 71.62%. Subsequently, wasted expired materials, with the proposed models have been successfully decreased to 95%.

  6. Factors that influence small animal veterinarians' opinions and actions regarding cost of care and effects of economic limitations on patient care and outcome and professional career satisfaction and burnout.

    PubMed

    Kipperman, Barry S; Kass, Philip H; Rishniw, Mark

    2017-04-01

    OBJECTIVE To determine small animal veterinarians' opinions and actions regarding costs of care, obstacles to client education about veterinary care costs, and effects of economic limitations on patient care and outcome and professional career satisfaction and burnout. DESIGN Cross-sectional survey. SAMPLE 1,122 small animal practitioners in the United States and Canada. PROCEDURES An online survey was sent to 37,036 veterinarians. Respondents provided information regarding perceived effects of client awareness of costs and pet health insurance coverage on various aspects of practice, the influence of client economic limitations on professional satisfaction and burnout, and proposals for addressing those effects. RESULTS The majority (620/1,088 [57%]) of respondents indicated that client economic limitations affected their ability to provide the desired care for their patients on a daily basis. Approximately half (527/1,071 [49%]) of respondents reported a moderate-to-substantial level of burnout, and many cited client economic limitations as an important contributing factor to burnout. Only 31% and 23% of respondents routinely discussed veterinary costs and pet insurance, respectively, with clients before pets became ill, and lack of time was cited as a reason for forgoing those discussions. Most respondents felt improved client awareness of veterinary costs and pet health insurance would positively affect patient care and client and veterinarian satisfaction. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested most small animal practitioners believe the veterinary profession needs to take action at educational and organizational levels to inform pet owners and educate and train veterinary students and veterinarians about the costs of veterinary care.

  7. Oxidative activation of acylguanidine prodrugs: intestinal presystemic activation in rats limits absorption and can be inhibited by co-administration of ketoconazole.

    PubMed

    Humphreys, W G; Obermeier, M T; Chong, S; Kimball, S D; Das, J; Chen, P; Moquin, R; Han, W-C; Gedamke, R; White, R E; Morrison, R A

    2003-01-01

    1. The disposition of acyl prodrugs was studied to improve the delivery of a guanidine-containing parent compound with poor membrane permeability and poor absorption. 2. The prodrugs were evaluated in vitro and in vivo for conversion to drug. Prodrugs were evaluated for hydrolytic or oxidative bioactivation in intestinal homogenate and rat liver S9 or microsomes. The disposition of the prodrugs in vivo was monitored in bile duct-cannulated rats. 3. Compounds with n-alkylacyl groups were efficiently bioactivated, but were hydrolysed before absorption. 4. Hydrolytic bioactivation could be blocked in vitro by branching in the alkyl chain. These compounds showed modest improvements in absorption, despite favourable permeability. Experiments with liver microsomes demonstrated efficient NADPH-dependent oxidative bioactivation, which was proposed to occur through a CYP-mediated side chain oxidation followed by cyclization and release of parent compound. Ketoconazole co-administration yielded approximately a twofold increase in absorption. 5. The hydrolytically stable prodrugs were successful in increasing absorption of parent drug and were efficiently bioactivated, but they did not yield increased systemic levels of drug.

  8. Postchallenge Administration of Brincidofovir Protects Healthy and Immune-Deficient Mice Reconstituted with Limited Numbers of T Cells from Lethal Challenge with IHD-J-Luc Vaccinia Virus

    PubMed Central

    McCullough, Kevin Tyler; Cruz, Stephanie; Thomas, Antonia; Diaz, Claudia G.; Keilholz, Laurie; Grossi, Irma M.; Trost, Lawrence C.; Golding, Hana

    2015-01-01

    ABSTRACT Protection from lethality by postchallenge administration of brincidofovir (BCV, CMX001) was studied in normal and immune-deficient (nude, nu/nu) BALB/c mice infected with vaccinia virus (VACV). Whole-body bioluminescence imaging was used to record total fluxes in the nasal cavity, lungs, spleen, and liver and to enumerate pox lesions on tails of mice infected via the intranasal route with 105 PFU of recombinant IHD-J-Luc VACV expressing luciferase. Areas under the flux curve (AUCs) were calculated for individual mice to assess viral loads. A three-dose regimen of 20 mg/kg BCV administered every 48 h starting either on day 1 or day 2 postchallenge protected 100% of mice. Initiating BCV treatment earlier was more efficient in reducing viral loads and in providing protection from pox lesion development. All BCV-treated mice that survived challenge were also protected from rechallenge with IHD-J-Luc or WRvFire VACV without additional treatment. In immune-deficient mice, BCV protected animals from lethality and reduced viral loads while animals were on the drug. Viral recrudescence occurred within 4 to 9 days, and mice succumbed ∼10 to 20 days after treatment termination. Nude mice reconstituted with 105 T cells prior to challenge with 104 PFU of IHD-J-Luc and treated with BCV postchallenge survived the infection, cleared the virus from all organs, and survived rechallenge with 105 PFU of IHD-J-Luc VACV without additional BCV treatment. Together, these data suggest that BCV protects immunocompetent and partially T cell-reconstituted immune-deficient mice from lethality, reduces viral dissemination in organs, prevents pox lesion development, and permits generation of VACV-specific memory. IMPORTANCE Mass vaccination is the primary element of the public health response to a smallpox outbreak. In addition to vaccination, however, antiviral drugs are required for individuals with uncertain exposure status to smallpox or for whom vaccination is contraindicated

  9. A New Concept of Enhancing Immuno-Chemotherapeutic Effects Against B16F10 Tumor via Systemic Administration by Taking Advantages of the Limitation of EPR Effect

    PubMed Central

    Yang, Yuting; Tai, Xiaowei; Shi, Kairong; Ruan, Shaobo; Qiu, Yue; Zhang, Zhirong; Xiang, Bing; He, Qin

    2016-01-01

    The enhanced permeability and retention (EPR) effect has been comfortably accepted, and extensively assumed as a keystone in the research on tumor-targeted drug delivery system. Due to the unsatisfied tumor-targeting efficiency of EPR effect being one conspicuous drawback, nanocarriers that merely relying on EPR effect are difficult to access the tumor tissue and consequently trigger efficient tumor therapy in clinic. In the present contribution, we break up the shackles of EPR effect on nanocarriers thanks to their universal distribution characteristic. We successfully design a paclitaxel (PTX) and alpha-galactosylceramide (αGC) co-loaded TH peptide (AGYLLGHINLHHLAHL(Aib)HHIL-Cys) -modified liposome (PTX/αGC-TH-Lip) and introduce a new concept of immuno-chemotherapy combination via accumulation of these liposomes at both spleen and tumor sites naturally and simultaneously. The PTX-initiated cytotoxicity attacks tumor cells at tumor sites, meanwhile, the αGC-triggered antitumor immune response emerges at spleen tissue. Different to the case that liposomes are loaded with sole drug, in this concept two therapeutic processes effectively reinforce each other, thereby elevating the tumor therapy efficiency significantly. The data demonstrates that the PTX/αGC-TH-Lip not only possess therapeutic effect against highly malignant B16F10 melanoma tumor, but also adjust the in vivo immune status and induce a more remarkable systemic antitumor immunity that could further suppress the growth of tumor at distant site. This work exhibits the capability of the PTX/αGC-TH-Lip in improving immune-chemotherapy against tumor after systemic administration. PMID:27698946

  10. 29 CFR 102.165 - Cost shifting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Cost shifting. 102.165 Section 102.165 Labor Regulations... by Administrative Offset § 102.165 Cost shifting. Costs incurred by the Agency in connection with... offset. Such costs may include administrative costs and attorneys fees....

  11. 13 CFR 107.855 - Interest rate ceiling and limitations on fees charged to Small Businesses (“Cost of Money”).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... you may charge more, do the following: (1) Choose a base rate for your Cost of Money computation. The base rate may be either the Debenture Rate currently in effect plus the applicable Charge determined.... (2) For a Loan, add 11 percentage points to the base rate; for a Debt Security, add 6...

  12. The utility of administrative data in helping the clinician understand and treat community-acquired pneumonia.

    PubMed

    Johnson, David

    2005-03-01

    We illustrate the benefits and limitations of administrative data when trying to understand diseases such as CAP. Administrative data provide an understanding of care provided or risk factors in unselected patients under actual practice conditions. Administrative data can supplement understandings gained from randomized trials in a timely and cost-efficient manner using data previously collected. As the use of administrative data increases, the type of data collected will change to reflect these new uses. Administrative data use may represent a practical solution in monitoring quality of care for entire populations.

  13. Administrative Synergy

    ERIC Educational Resources Information Center

    Hewitt, Kimberly Kappler; Weckstein, Daniel K.

    2012-01-01

    One of the biggest obstacles to overcome in creating and sustaining an administrative professional learning community (PLC) is time. Administrators are constantly deluged by the tyranny of the urgent. It is a Herculean task to carve out time for PLCs, but it is imperative to do so. In this article, the authors describe how an administrative PLC…

  14. 45 CFR 2516.710 - What are the limits on the use of funds?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 2516.710 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR... applying the limitation on administrative costs, the Corporation may approve one of the following methods... this method; and (B) Unreimbursed indirect costs may be applied to meeting operational...

  15. 20 CFR 632.38 - Classification of costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Administrative costs consist of all direct and indirect costs associated with the management of the grantee's...; classroom space and utility costs; employability assessment; job related counseling for participants;...

  16. Region 11 Health Care and Administration Costs

    DTIC Science & Technology

    2001-09-01

    average length of stay , we’ve used average values drawn from 1999 data representing averages across the Kaiser-Permanente health care system (including the... average length of stay (ALOS). Here, we provide the ALOS for enrollees who used civilian facilities (through the contractor) and those who used the MTF

  17. 20 CFR 633.304 - Section 402 cost allocation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... associated with the management of the program. Administrative costs shall be limited to those necessary to... which affect those program participants who are in either a work environment, or classroom setting (including classroom training in conjunction with Vocational Exploration or Job Readiness or...

  18. How much does curation cost?

    PubMed

    Karp, Peter D

    2016-01-01

    NIH administrators have recently expressed concerns about the cost of curation for biological databases. However, they did not articulate the exact costs of curation. Here we calculate the cost of biocuration of articles for the EcoCyc database as $219 per article over a 5-year period. That cost is 6-15% of the cost of open-access publication fees for publishing biomedical articles, and we estimate that cost is 0.088% of the cost of the overall research project that generated the experimental results. Thus, curation costs are small in an absolute sense, and represent a miniscule fraction of the cost of the research.

  19. How much does curation cost?

    PubMed Central

    2016-01-01

    NIH administrators have recently expressed concerns about the cost of curation for biological databases. However, they did not articulate the exact costs of curation. Here we calculate the cost of biocuration of articles for the EcoCyc database as $219 per article over a 5-year period. That cost is 6–15% of the cost of open-access publication fees for publishing biomedical articles, and we estimate that cost is 0.088% of the cost of the overall research project that generated the experimental results. Thus, curation costs are small in an absolute sense, and represent a miniscule fraction of the cost of the research. PMID:27504008

  20. 44 CFR 209.11 - Grant administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Grant administration. 209.11... Grant administration. (a) Cost share. We may contribute up to 75 percent of the total eligible costs... eligible costs for the grant. The State or any subgrantee cannot use funds that we provide under this...

  1. 44 CFR 209.11 - Grant administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Grant administration. 209.11... Grant administration. (a) Cost share. We may contribute up to 75 percent of the total eligible costs... eligible costs for the grant. The State or any subgrantee cannot use funds that we provide under this...

  2. 44 CFR 209.11 - Grant administration.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Grant administration. 209.11... Grant administration. (a) Cost share. We may contribute up to 75 percent of the total eligible costs... eligible costs for the grant. The State or any subgrantee cannot use funds that we provide under this...

  3. Using Administrative Data for Longitudinal Substance Abuse Research

    PubMed Central

    Evans, Elizabeth; Grella, Christine E.; Murphy, Debra A.; Hser, Yih-Ing

    2008-01-01

    The utilization of administrative data in substance abuse research has become more widespread than ever. This selective review synthesizes recent extant research from 31 articles to consider what has been learned from using administrative data to conduct longitudinal substance abuse research in four overlapping areas: (1) service access and utilization, (2) underrepresented populations, (3) treatment outcomes, and (4) cost analysis. Despite several notable limitations, administrative data contribute valuable information, particularly in the investigation of service system interactions and outcomes among substance abusers as they unfold and influence each other over the long term. This critical assessment of the advantages and disadvantages of using existing administrative data within a longitudinal framework should stimulate innovative thinking regarding future applications of administrative data for longitudinal substance abuse research purposes. PMID:18679805

  4. 78 FR 9771 - Federal Highway Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... Federal Highway Administration Notice of Final Federal Agency Action on Proposed Transportation Project in Illinois and Indiana AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of limitation on..., Federal Highway Administration, 3250 Executive Park Drive, Springfield, Illinois 62703, Phone: (217)...

  5. Administrative Ecology

    ERIC Educational Resources Information Center

    McGarity, Augustus C., III; Maulding, Wanda

    2007-01-01

    This article discusses how all four facets of administrative ecology help dispel the claims about the "impossibility" of the superintendency. These are personal ecology, professional ecology, organizational ecology, and community ecology. Using today's superintendency as an administrative platform, current literature describes a preponderance of…

  6. 23 CFR 140.505 - Reimbursable costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Reimbursable costs. 140.505 Section 140.505 Highways... Administrative Settlement Costs-Contract Claims § 140.505 Reimbursable costs. (a) Federal funds may participate in administrative settlement costs which are: (1) Incurred after notice of claim, (2)...

  7. 28 CFR 100.11 - Allowable costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Allowable costs. 100.11 Section 100.11 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) COST RECOVERY REGULATIONS, COMMUNICATIONS ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.11 Allowable costs. (a) Costs that are eligible...

  8. Cost Accounting: Production and Equipment Services.

    ERIC Educational Resources Information Center

    Schmid, William T.

    Cost accounting for audiovisual productions should include direct costs, and, in some cases, the media administrator may have to calculate a per-hour surcharge for general operating overhead as well. Such procedures enable the administrator to determine cost effectiveness, to control cost overruns, and to generate more staff efficiency. Cost…

  9. Using National Data to Estimate Average Cost Effectiveness of EFNEP Outcomes by State/Territory

    ERIC Educational Resources Information Center

    Baral, Ranju; Davis, George C.; Blake, Stephanie; You, Wen; Serrano, Elena

    2013-01-01

    This report demonstrates how existing national data can be used to first calculate upper limits on the average cost per participant and per outcome per state/territory for the Expanded Food and Nutrition Education Program (EFNEP). These upper limits can then be used by state EFNEP administrators to obtain more precise estimates for their states,…

  10. 77 FR 11191 - Insurance Cost Information Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... National Highway Traffic Safety Administration Insurance Cost Information Regulation AGENCY: National... insurance cost information booklet that all car dealers must make available to prospective purchasers... differences in passenger vehicle collision loss experience that could affect auto insurance costs....

  11. Statewide Implementation of Parenting with Love and Limits Among Youth with Co-Existing Internalizing and Externalizing Functional Impairments Reduces Return to Service Rates and Treatment Costs.

    PubMed

    Sterrett-Hong, Emma M; Karam, Eli; Kiaer, Lynn

    2017-01-24

    Many community mental health (CMH) systems contain inefficiencies, contributing to unmet need for services among youth. Using a quasi-experimental research design, we examined the implementation of an adapted structural-strategic family intervention, Parenting with Love and Limits, in a state CMH system to increase efficiency of services to youth with co-existing internalizing and externalizing functional impairments (PLL n = 296; Treatment-As-Usual n = 296; 54% male; 81% Caucasian). Youth receiving PLL experienced shorter treatment durations and returned to CMH services at significantly lower rates than youth receiving treatment-as-usual. They also demonstrated significant decreases in internalizing and externalizing symptoms over time. Findings lay the foundation for further examination of the role of an adapted structural-strategic family treatment in increasing the efficiency of CMH systems.

  12. 47 CFR 54.715 - Administrative expenses of the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... 54.715 Section 54.715 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... expenses may include, but are not limited to, salaries of officers and operations personnel, the costs of borrowing funds, equipment costs, operating expenses, directors' expenses, and costs associated...

  13. Dried tube specimens: a simple and cost-effective method for preparation of HIV proficiency testing panels and quality control materials for use in resource-limited settings.

    PubMed

    Parekh, Bharat S; Anyanwu, Juliana; Patel, Hetal; Downer, Marie; Kalou, Mireille; Gichimu, Catherine; Keipkerich, Bera Steven; Clement, Nelly; Omondi, Michael; Mayer, Oren; Ou, Chin-Yih; Nkengasong, John N

    2010-02-01

    HIV testing has rapidly expanded worldwide, but proficiency testing (PT) programs to monitor and improve the quality of testing are often lacking in resource-limited settings (RLS). Traditional PT programs and quality control reagents use serum or plasma specimens requiring stringent conditions for storage and transportation. A novel, simple and easy to use approach, based on dried tube specimens (DTS), was developed that can help monitor the quality of HIV antibody testing in RLS. DTS were prepared by drying 20 microl of specimen overnight at room temperature. The addition of a green dye (0.1%) made the DTS pellets visible without affecting the test results. Before testing, the DTS were rehydrated with 200 microl of PBS-Tween buffer. A panel of 303 DTS samples (135 HIV positive and 168 HIV negative) was evaluated with two rapid tests. Sensitivity and specificity with the Determine HIV-1/2 test were 99.3% and 99.4%, respectively, and with OraQuick were 98.5% and 100%, respectively. Stability studies showed that HIV-specific antibodies in the DTS specimens were stable at 4 degrees C and 25 degrees C for 4 weeks, with only marginal decline at 37 degrees C and 45 degrees C over 4 weeks. The DTS-based PT program was piloted successfully in 24 testing sites in Kenya. Results demonstrate that the DTS is a simple to use, practical method to prepare and distribute PT panels and quality control specimens to monitor HIV testing practices in RLS.

  14. Activity-Based Costing: A Cost Management Tool.

    ERIC Educational Resources Information Center

    Turk, Frederick J.

    1993-01-01

    In college and university administration, overhead costs are often charged to programs indiscriminately, whereas the support activities that underlie those costs remain unanalyzed. It is time for institutions to decrease ineffective use of resources. Activity-based management attributes costs more accurately and can improve efficiency. (MSE)

  15. 42 CFR 417.540 - Enrollment costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Enrollment costs. 417.540 Section 417.540 Public... PLANS Medicare Payment: Cost Basis § 417.540 Enrollment costs. (a) Principle. Enrollment costs are... of costs included. Enrollment costs include, but are not limited to, reasonable costs incurred...

  16. 42 CFR 417.540 - Enrollment costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Enrollment costs. 417.540 Section 417.540 Public... PLANS Medicare Payment: Cost Basis § 417.540 Enrollment costs. (a) Principle. Enrollment costs are... of costs included. Enrollment costs include, but are not limited to, reasonable costs incurred...

  17. Centralized administrative services management.

    PubMed

    Freed, D H

    1994-06-01

    Virtually every hospital has imposed guidelines or controls on one or more administrative service expenses. However, the actual deployment of such strategies is often voluntary, decentralized, disjointed and episodic. An alternative approach is to cluster administrative elements across hospital departments and make them the responsibility of a dedicated manager. This approach treats administrative services as an organizing principle with uniform, predictable standards of service and cost. Customer requirements for products and services are met without the need for them to physically manage that process. Materiel managers can demonstrate a leadership role by applying their professionalism and know-how to a set of products and services traditionally ignored or dealt with in an uncoordinated manner. While some initial resistance can be expected as traditional barriers are disassembled, the results should be very rewarding for the hospital and materiel manager alike.

  18. 29 CFR 102.171 - Cost shifting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Cost shifting. 102.171 Section 102.171 Labor Regulations... By Federal Income Tax Refund Offset § 102.171 Cost shifting. Costs incurred by the Agency in... amount of the offset. Such costs may include administrative costs and attorneys fees....

  19. Engineering Administration.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    This book is intended to acquaint naval engineering officers with their duties in the engineering department. Standard shipboard organizations are analyzed in connection with personnel assignments, division operations, and watch systems. Detailed descriptions are included for the administration of directives, ship's bills, damage control, training…

  20. Administrative IT

    ERIC Educational Resources Information Center

    Grayson, Katherine, Ed.

    2006-01-01

    When it comes to Administrative IT solutions and processes, best practices range across the spectrum. Enterprise resource planning (ERP), student information systems (SIS), and tech support are prominent and continuing areas of focus. But widespread change can also be accomplished via the implementation of campuswide document imaging and sharing,…