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Sample records for administrative protective order

  1. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Order and Dockets Unit. 351.103 Section 351.103 Customs Duties INTERNATIONAL TRADE ADMINISTRATION... Unit and Administrative Protective Order and Dockets Unit. (a) Import Administration's Central Records... Administration's Administrative Protective Order and Dockets Unit (APO/Dockets Unit) is located in Room 1870,...

  2. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Order and Dockets Unit. 351.103 Section 351.103 Customs Duties INTERNATIONAL TRADE ADMINISTRATION... Unit and Administrative Protective Order and Dockets Unit. (a) Import Administration's Central Records... (see § 351.104). (b) Import Administration's Administrative Protective Order and Dockets Unit...

  3. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Order and Dockets Unit. 351.103 Section 351.103 Customs Duties INTERNATIONAL TRADE ADMINISTRATION... Unit and Administrative Protective Order and Dockets Unit. (a) Import Administration's Central Records... (see § 351.104). (b) Import Administration's Administrative Protective Order and Dockets Unit...

  4. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Order and Dockets Unit. 351.103 Section 351.103 Customs Duties INTERNATIONAL TRADE ADMINISTRATION... Unit and Administrative Protective Order and Dockets Unit. (a) Import Administration's Central Records... Administration's Administrative Protective Order and Dockets Unit (APO/Dockets Unit) is located in Room 1870,...

  5. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Order and Dockets Unit. 351.103 Section 351.103 Customs Duties INTERNATIONAL TRADE ADMINISTRATION... Unit and Administrative Protective Order and Dockets Unit. (a) Enforcement and Compliance's Central... (see § 351.104). (b) Enforcement and Compliance's Administrative Protective Order and Dockets Unit...

  6. 29 CFR 18.15 - Protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Protective orders. 18.15 Section 18.15 Labor Office of the... ADMINISTRATIVE LAW JUDGES General § 18.15 Protective orders. (a) Upon motion by a party or the person from whom discovery is sought, and for good cause shown, the administrative law judge may make any order which...

  7. 29 CFR 18.15 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Protective orders. 18.15 Section 18.15 Labor Office of the... ADMINISTRATIVE LAW JUDGES General § 18.15 Protective orders. (a) Upon motion by a party or the person from whom discovery is sought, and for good cause shown, the administrative law judge may make any order which...

  8. 29 CFR 18.15 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Protective orders. 18.15 Section 18.15 Labor Office of the... ADMINISTRATIVE LAW JUDGES General § 18.15 Protective orders. (a) Upon motion by a party or the person from whom discovery is sought, and for good cause shown, the administrative law judge may make any order which...

  9. 43 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Protective order. 35.24 Section 35.24 Public Lands: Interior Office of the Secretary of the Interior ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS AND STATEMENTS § 35.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with...

  10. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Protective order. 185.125 Section 185.125... § 185.125 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  11. 28 CFR 71.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Protective order. 71.24 Section 71.24....24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  12. 28 CFR 71.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Protective order. 71.24 Section 71.24....24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  13. 28 CFR 76.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Protective order. 76.24 Section 76.24... PENALTIES FOR POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.24 Protective order. (a) A party or a... motion for a protective order with respect to discovery sought by an opposing party or with respect...

  14. 28 CFR 76.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Protective order. 76.24 Section 76.24... PENALTIES FOR POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.24 Protective order. (a) A party or a... motion for a protective order with respect to discovery sought by an opposing party or with respect...

  15. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.125 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  16. Protective orders: questions and conundrums.

    PubMed

    Logan, T K; Shannon, Lisa; Walker, Robert; Faragher, Teri Marie

    2006-07-01

    Current media portrayal of protective orders is often negative, focusing on weaknesses in how protective orders are obtained and enforced. This review of research findings on protective orders examines issues and suggests areas in need of future research to clarify and improve public policy. More specifically, this review has five main objectives: (a) to provide background information about partner violence and the need for protective orders; (b) to describe what protective orders are, how many women obtain them, and the advantages and disadvantages of obtaining protective orders; (c) to examine characteristics of women who seek protective orders; (d) to explore research on whether protective orders actually increase women's safety; and (e) to highlight opportunities and gaps in the practice and research literature regarding the use of protective orders for women with violent partners or ex-partners. PMID:16785286

  17. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... administrative investigation not be disclosed or be disclosed only in a designated way; or (9) That the...

  18. 45 CFR 79.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Protective order. 79.24 Section 79.24 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES § 79.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by...

  19. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  20. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  1. 14 CFR 1264.123 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Protective order. 1264.123 Section 1264.123 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL... a motion for a protective order with respect to discovery sought by an opposing party or...

  2. 14 CFR 1264.123 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Protective order. 1264.123 Section 1264.123 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL... a motion for a protective order with respect to discovery sought by an opposing party or...

  3. 28 CFR 76.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Protective order. 76.24 Section 76.24... PENALTIES FOR POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.24 Protective order. (a) A party or a prospective witness or deponent may seek to limit the availability or disclosure of evidence by filing...

  4. 28 CFR 76.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Protective order. 76.24 Section 76.24... PENALTIES FOR POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.24 Protective order. (a) A party or a prospective witness or deponent may seek to limit the availability or disclosure of evidence by filing...

  5. 28 CFR 71.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., seeking to limit the availability or disclosure of evidence. (b) In issuing a protective order, the ALJ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Protective order. 71.24 Section 71.24... FRAUD CIVIL REMEDIES ACT OF 1986 Implementation for Actions Initiated by the Department of Justice §...

  6. 28 CFR 71.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., seeking to limit the availability or disclosure of evidence. (b) In issuing a protective order, the ALJ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Protective order. 71.24 Section 71.24... FRAUD CIVIL REMEDIES ACT OF 1986 Implementation for Actions Initiated by the Department of Justice §...

  7. 14 CFR 1264.123 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Protective order. 1264.123 Section 1264.123 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL PENALTIES ACT OF 1986 § 1264.123 Protective order. (a) A party or a prospective witness or deponent may...

  8. Localization protected quantum order

    NASA Astrophysics Data System (ADS)

    Nandkishore, Rahul

    2015-03-01

    Many body localization occurs in isolated quantum systems, usually with strong disorder, and is marked by absence of dissipation, absence of thermal equilibration, and a memory of the initial conditions that survives in local observables for arbitrarily long times. The many body localized regime is a non-equilibrium, strongly disordered, non-self averaging regime that presents a new frontier for quantum statistical mechanics. In this talk, I point out that there exists a vast zoo of correlated many body localized states of matter, which may be classified using familiar notions of spontaneous symmetry breaking and topological order. I will point out that in the many body localized regime, spontaneous symmetry breaking can occur even at high energy densities in one dimensional systems, and topological order can occur even without a bulk gap. I will also discuss the phenomenology of imperfectly isolated many body localized systems, which are weakly coupled to a heat bath. I will conclude with a brief discussion of how these phenomena may best be detected in experiments. Collaborators: David Huse, S.L. Sondhi, Arijeet Pal, Vadim Oganesyan, A.C. Potter, Sarang Gopalakrishnan, S. Johri, R.N. Bhatt.

  9. 45 CFR 79.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Protective order. 79.24 Section 79.24 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES § 79... being sealed be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  10. 49 CFR 386.39 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Protective orders. 386.39 Section 386.39 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RULES OF PRACTICE FOR...

  11. 49 CFR 386.39 - Protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Protective orders. 386.39 Section 386.39 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RULES OF PRACTICE FOR MOTOR CARRIER, INTERMODAL EQUIPMENT...

  12. 14 CFR 1264.123 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Protective order. 1264.123 Section 1264.123 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL... presiding officer; (8) That a trade secret or other confidential research, development,...

  13. 14 CFR 1264.123 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Protective order. 1264.123 Section 1264.123 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL... presiding officer; (8) That a trade secret or other confidential research, development,...

  14. 21 CFR 17.28 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of personal privacy, or other information that would be withheld from public disclosure under 21 CFR... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL CIVIL MONEY... protective order with respect to discovery sought by a party or with respect to the hearing, seeking to...

  15. 21 CFR 17.28 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of personal privacy, or other information that would be withheld from public disclosure under 21 CFR... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL CIVIL MONEY... protective order with respect to discovery sought by a party or with respect to the hearing, seeking to...

  16. 28 CFR 68.42 - In camera and protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false In camera and protective orders. 68.42 Section 68.42 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE... In camera and protective orders. (a) Privileged communications. Upon application of any person,...

  17. 29 CFR 18.46 - In camera and protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false In camera and protective orders. 18.46 Section 18.46 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.46 In camera and protective orders. (a) Privileges....

  18. 28 CFR 68.42 - In camera and protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false In camera and protective orders. 68.42 Section 68.42 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE... In camera and protective orders. (a) Privileged communications. Upon application of any person,...

  19. 29 CFR 18.46 - In camera and protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false In camera and protective orders. 18.46 Section 18.46 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.46 In camera and protective orders. (a) Privileges....

  20. 28 CFR 68.42 - In camera and protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false In camera and protective orders. 68.42 Section 68.42 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE... In camera and protective orders. (a) Privileged communications. Upon application of any person,...

  1. 29 CFR 18.46 - In camera and protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true In camera and protective orders. 18.46 Section 18.46 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.46 In camera and protective orders. (a) Privileges....

  2. 29 CFR 18.46 - In camera and protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false In camera and protective orders. 18.46 Section 18.46 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.46 In camera and protective orders. (a) Privileges....

  3. 28 CFR 68.42 - In camera and protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false In camera and protective orders. 68.42 Section 68.42 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE... In camera and protective orders. (a) Privileged communications. Upon application of any person,...

  4. 29 CFR 18.46 - In camera and protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true In camera and protective orders. 18.46 Section 18.46 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.46 In camera and protective orders. (a) Privileges....

  5. 28 CFR 68.42 - In camera and protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false In camera and protective orders. 68.42 Section 68.42 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE... In camera and protective orders. (a) Privileged communications. Upon application of any person,...

  6. 40 CFR 27.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Protective order. 27.24 Section 27.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by...

  7. 40 CFR 27.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Protective order. 27.24 Section 27.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by...

  8. 40 CFR 27.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Protective order. 27.24 Section 27.24... Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order... availability or disclosure of evidence. (b) In issuing a protective order, the presiding officer may make...

  9. 10 CFR 205.198A - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Protective order. 205.198A Section 205.198A Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Notice of Probable Violation, Remedial Order, Notice of Proposed Disallowance, and Order of Disallowance § 205.198A Protective order. A participant...

  10. 41 CFR 105-70.024 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.024 Protective order... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  11. 41 CFR 105-70.024 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.024 Protective order... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  12. 14 CFR 17.9 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Protective orders. 17.9 Section 17.9... PROCEDURES FOR PROTESTS AND CONTRACT DISPUTES General § 17.9 Protective orders. (a) The ODRA may issue protective orders addressing the treatment of protected information, including protected information...

  13. 43 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... protective order, the ALJ may make any order which justice requires to protect a party or person from... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Protective order. 35.24 Section 35.24... CLAIMS AND STATEMENTS § 35.24 Protective order. (a) A party or a prospective witness or deponent may...

  14. 15 CFR 25.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Protective order. 25.24 Section 25.24... Protective order. (a) A party of a prospective witness or deponent may file a motion for a protective order... the availability or disclosure of evidence. (b) In issuing a protective order, the ALJ may make...

  15. 22 CFR 521.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Protective order. 521.24 Section 521.24 Foreign... Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order... the availability or disclosure of evidence. (b) In issuing a protective order, the ALJ may make...

  16. 15 CFR 25.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Protective order. 25.24 Section 25.24... Protective order. (a) A party of a prospective witness or deponent may file a motion for a protective order... the availability or disclosure of evidence. (b) In issuing a protective order, the ALJ may make...

  17. 10 CFR 1013.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Protective order. 1013.24 Section 1013.24 Energy... order. (a) A party or a prospective witness or deponent may file a motion for a protective order with... availability or disclosure of evidence. (b) In issuing a protective order, the ALJ may make any order...

  18. 4 CFR 21.4 - Protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 4 Accounts 1 2011-01-01 2011-01-01 false Protective orders. 21.4 Section 21.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.4 Protective orders. (a) At the request of... copies of documents omitting protected information. Because a protective order serves to facilitate...

  19. 4 CFR 21.4 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Protective orders. 21.4 Section 21.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.4 Protective orders. (a) At the request of a party or on its own initiative, GAO may issue a protective order controlling the treatment of protected information. Such...

  20. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... certain confidential business information under administrative protective order. In an investigation...

  1. 19 CFR 206.37 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... business information under administrative protective order. 206.37 Section 206.37 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... business information under administrative protective order. Except in the case of an investigation...

  2. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... certain confidential business information under administrative protective order. In an investigation...

  3. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... certain confidential business information under administrative protective order. In an investigation...

  4. 19 CFR 206.37 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... business information under administrative protective order. 206.37 Section 206.37 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... business information under administrative protective order. Except in the case of an investigation...

  5. 33 CFR 20.606 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Protective orders. 20.606 Section....606 Protective orders. (a) In considering a motion for an order of discovery—or a motion, by a party... may enter any order that justice requires, to protect a person from annoyance,...

  6. 24 CFR 26.44 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Protective orders. 26.44 Section 26... orders. (a) A party, a prospective witness, or a deponent may file a motion for a protective order with... availability or disclosure of evidence. (b) Protective orders may be issued by an ALJ if the ALJ...

  7. 24 CFR 26.44 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Protective orders. 26.44 Section 26... orders. (a) A party, a prospective witness, or a deponent may file a motion for a protective order with... availability or disclosure of evidence. (b) Protective orders may be issued by an ALJ if the ALJ...

  8. 6 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Protective order. 13.24 Section 13.24 Domestic... Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the hearing, seeking to...

  9. 49 CFR 31.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Protective order. 31.24 Section 31.24 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  10. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Protective order. 224.24 Section 224.24 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to...

  11. 4 CFR 21.4 - Protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 4 Accounts 1 2013-01-01 2013-01-01 false Protective orders. 21.4 Section 21.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.4 Protective orders. (a) At the request of a party or on its own initiative, GAO may issue a protective order controlling the treatment...

  12. 38 CFR 42.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Protective order. 42.24... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by...

  13. 38 CFR 42.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Protective order. 42.24... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by...

  14. 29 CFR 22.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Protective order. 22.24 Section 22.24 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought...

  15. 31 CFR 16.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Protective order. 16.24 Section 16.24... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party...

  16. 49 CFR 386.39 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Protective orders. 386.39 Section 386.39... General Rules and Hearings § 386.39 Protective orders. Upon motion by a party or other person from whom..., if one has been appointed, may make any order which justice requires to protect a party or...

  17. 12 CFR 308.523 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Protective order. 308.523 Section 308.523 Banks... AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.523 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought...

  18. 45 CFR 79.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Protective order. 79.24 Section 79.24 Public....24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  19. 43 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Protective order. 35.24 Section 35.24... CLAIMS AND STATEMENTS § 35.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or...

  20. 34 CFR 33.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Protective order. 33.24 Section 33.24 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  1. 45 CFR 79.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Protective order. 79.24 Section 79.24 Public....24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  2. 34 CFR 33.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Protective order. 33.24 Section 33.24 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  3. 49 CFR 31.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Protective order. 31.24 Section 31.24 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  4. 34 CFR 33.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Protective order. 33.24 Section 33.24 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  5. 24 CFR 180.535 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Protective orders. 180.535 Section... Protective orders. (a) Upon motion of a party or a person from whom discovery is sought or in accordance with § 180.540(c), and for good cause shown, the ALJ may make appropriate orders to protect a party or...

  6. 49 CFR 31.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Protective order. 31.24 Section 31.24 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order...

  7. 4 CFR 21.4 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 4 Accounts 1 2014-01-01 2013-01-01 true Protective orders. 21.4 Section 21.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.4 Protective orders. (a) At the request of a party or on its own initiative, GAO may issue a protective order controlling the treatment...

  8. 29 CFR 22.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Protective order. 22.24 Section 22.24 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought...

  9. 29 CFR 22.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Protective order. 22.24 Section 22.24 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought...

  10. 33 CFR 20.606 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Protective orders. 20.606 Section....606 Protective orders. (a) In considering a motion for an order of discovery—or a motion, by a party or other person from whom discovery is sought, to reconsider or amend an order of discovery—the...

  11. 33 CFR 20.606 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Protective orders. 20.606 Section....606 Protective orders. (a) In considering a motion for an order of discovery—or a motion, by a party or other person from whom discovery is sought, to reconsider or amend an order of discovery—the...

  12. 40 CFR 29.4 - What are the Administrator's general responsibilities under the Order?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false What are the Administrator's general responsibilities under the Order? 29.4 Section 29.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL INTERGOVERNMENTAL REVIEW OF ENVIRONMENTAL PROTECTION AGENCY PROGRAMS AND ACTIVITIES § 29.4 What are the Administrator's...

  13. 40 CFR 27.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Protective order. 27.24 Section 27.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.24... confidential research, development, or commercial information, or facts pertaining to any...

  14. 40 CFR 27.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Protective order. 27.24 Section 27.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.24... confidential research, development, or commercial information, or facts pertaining to any...

  15. 34 CFR 33.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Protective order. 33.24 Section 33.24 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.24 Protective order... opened only by order of the ALJ. (8) That a trade secret or other confidential research,...

  16. 34 CFR 33.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Protective order. 33.24 Section 33.24 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.24 Protective order... opened only by order of the ALJ. (8) That a trade secret or other confidential research,...

  17. 49 CFR 31.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Protective order. 31.24 Section 31.24 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.24 Protective order... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  18. 49 CFR 31.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Protective order. 31.24 Section 31.24 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.24 Protective order... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  19. 41 CFR 105-70.024 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Protective order. 105-70.024 Section 105-70.024 Public Contracts and Property Management Federal Property Management... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.024 Protective...

  20. 41 CFR 105-70.024 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Protective order. 105-70.024 Section 105-70.024 Public Contracts and Property Management Federal Property Management... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.024 Protective...

  1. 22 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Protective order. 35.24 Section 35.24 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an...

  2. 12 CFR 308.523 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.523 Protective order. (a) A party or a... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  3. 12 CFR 308.523 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.523 Protective order. (a) A party or a... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  4. 12 CFR 308.523 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.523 Protective order. (a) A party or a... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  5. 10 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Protective order. 13.24 Section 13.24 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.24 Protective order. (a) A party or a prospective... information enclosed in sealed envelopes to be opened as directed by the ALJ....

  6. 38 CFR 42.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Protective order. 42.24 Section 42.24 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.24 Protective order. (a) A party or a prospective witness or deponent may file a...

  7. 29 CFR 22.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Protective order. 22.24 Section 22.24 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  8. 22 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Protective order. 35.24 Section 35.24 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  9. 10 CFR 1013.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Protective order. 1013.24 Section 1013.24 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  10. 10 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Protective order. 13.24 Section 13.24 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  11. 10 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Protective order. 13.24 Section 13.24 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  12. 10 CFR 1013.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Protective order. 1013.24 Section 1013.24 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  13. 10 CFR 1013.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Protective order. 1013.24 Section 1013.24 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  14. 22 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Protective order. 35.24 Section 35.24 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  15. 10 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Protective order. 13.24 Section 13.24 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  16. 22 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Protective order. 35.24 Section 35.24 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  17. 29 CFR 22.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Protective order. 22.24 Section 22.24 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  18. 22 CFR 35.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Protective order. 35.24 Section 35.24 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  19. 10 CFR 1013.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Protective order. 1013.24 Section 1013.24 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.24 Protective... only by order of the ALJ; (8) That a trade secret or other confidential research,...

  20. 10 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Protective order. 13.24 Section 13.24 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  1. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Protective order. 224.24 Section 224.24 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  2. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Protective order. 224.24 Section 224.24 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  3. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Protective order. 224.24 Section 224.24 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  4. 22 CFR 224.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Protective order. 224.24 Section 224.24 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  5. 47 CFR 1.313 - Protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Protective orders. 1.313 Section 1.313... and Preservation of Evidence § 1.313 Protective orders. The use of the procedures set forth in §§ 1.311 through 1.325 of this part is subject to control by the presiding officer, who may issue any...

  6. 21 CFR 17.28 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of personal privacy, or other information that would be withheld from public disclosure under 21 CFR... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Protective order. 17.28 Section 17.28 Food and... PENALTIES HEARINGS § 17.28 Protective order. (a) A party or a prospective witness may file a motion for...

  7. 47 CFR 1.313 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Protective orders. 1.313 Section 1.313... and Preservation of Evidence § 1.313 Protective orders. The use of the procedures set forth in §§ 1.311 through 1.325 of this part is subject to control by the presiding officer, who may issue any...

  8. 31 CFR 16.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.24 Protective order. (a) A party or a prospective witness or... confidential research, development, commercial information, or facts pertaining to any criminal...

  9. 20 CFR 355.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  10. 31 CFR 16.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.24 Protective order. (a) A party or a prospective witness or... confidential research, development, commercial information, or facts pertaining to any criminal...

  11. 20 CFR 355.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  12. 31 CFR 16.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.24 Protective order. (a) A party or a prospective witness or... confidential research, development, commercial information, or facts pertaining to any criminal...

  13. 38 CFR 42.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  14. 38 CFR 42.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.24 Protective order. (a) A party or a prospective... trade secret or other confidential research, development, commercial information, or facts pertaining...

  15. 20 CFR 355.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  16. 20 CFR 355.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.24 Protective order. (a) A party or a... trade secret or other confidential research, development, commercial information, or facts pertaining...

  17. 24 CFR 180.535 - Protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... order, to make all or part of the showing of good cause in camera. If such a showing is made, upon motion of the party or other person from whom discovery is sought, an in camera record of the proceedings may be made. If the ALJ enters a protective order, any in camera record of such showing shall...

  18. 24 CFR 180.535 - Protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... order, to make all or part of the showing of good cause in camera. If such a showing is made, upon motion of the party or other person from whom discovery is sought, an in camera record of the proceedings may be made. If the ALJ enters a protective order, any in camera record of such showing shall...

  19. 24 CFR 180.535 - Protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... order, to make all or part of the showing of good cause in camera. If such a showing is made, upon motion of the party or other person from whom discovery is sought, an in camera record of the proceedings may be made. If the ALJ enters a protective order, any in camera record of such showing shall...

  20. 15 CFR 25.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Protective order. 25.24 Section 25.24 Commerce and Foreign Trade Office of the Secretary of Commerce PROGRAM Fraud Civil Remedies § 25.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  1. 22 CFR 521.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Protective order. 521.24 Section 521.24 Foreign Relations BROADCASTING BOARD OF GOVERNORS IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 521.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  2. 15 CFR 25.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Protective order. 25.24 Section 25.24 Commerce and Foreign Trade Office of the Secretary of Commerce PROGRAM Fraud Civil Remedies § 25.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  3. 6 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Protective order. 13.24 Section 13.24 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  4. 6 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Protective order. 13.24 Section 13.24 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  5. 22 CFR 521.24 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Protective order. 521.24 Section 521.24 Foreign Relations BROADCASTING BOARD OF GOVERNORS IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 521.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  6. 6 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Protective order. 13.24 Section 13.24 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  7. 15 CFR 25.24 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Protective order. 25.24 Section 25.24 Commerce and Foreign Trade Office of the Secretary of Commerce PROGRAM Fraud Civil Remedies § 25.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  8. 22 CFR 521.24 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Protective order. 521.24 Section 521.24 Foreign Relations BROADCASTING BOARD OF GOVERNORS IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 521.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  9. 6 CFR 13.24 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Protective order. 13.24 Section 13.24 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.24... opened only by order of the ALJ; (8) That a trade secret or other confidential research,...

  10. 24 CFR 180.535 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... order, to make all or part of the showing of good cause in camera. If such a showing is made, upon motion of the party or other person from whom discovery is sought, an in camera record of the proceedings may be made. If the ALJ enters a protective order, any in camera record of such showing shall...

  11. 15 CFR Supplement No. 2 to Part 736 - Administrative Orders

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Administrative Orders No. Supplement No. 2 to Part 736 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... PROHIBITIONS Pt. 736, Supp. 2 Supplement No. 2 to Part 736—Administrative Orders Administrative Order...

  12. 15 CFR Supplement No. 2 to Part 736 - Administrative Orders

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Administrative Orders No. Supplement No. 2 to Part 736 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... PROHIBITIONS Pt. 736, Supp. 2 Supplement No. 2 to Part 736—Administrative Orders Administrative Order...

  13. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... information under administrative protective order. In an investigation under section 421(b) or (o) of...

  14. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... information under administrative protective order. In an investigation under section 421(b) or (o) of...

  15. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL... information under administrative protective order. In an investigation under section 421(b) or (o) of...

  16. 15 CFR 764.6 - Protective administrative measures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Protective administrative measures. 764.6 Section 764.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... ENFORCEMENT AND PROTECTIVE MEASURES § 764.6 Protective administrative measures. (a) License...

  17. 15 CFR 764.6 - Protective administrative measures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Protective administrative measures. 764.6 Section 764.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... ENFORCEMENT AND PROTECTIVE MEASURES § 764.6 Protective administrative measures. (a) License...

  18. 15 CFR 764.6 - Protective administrative measures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Protective administrative measures. 764.6 Section 764.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... ENFORCEMENT AND PROTECTIVE MEASURES § 764.6 Protective administrative measures. (a) License...

  19. 15 CFR 764.6 - Protective administrative measures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Protective administrative measures. 764.6 Section 764.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... ENFORCEMENT AND PROTECTIVE MEASURES § 764.6 Protective administrative measures. (a) License...

  20. 7 CFR 1000.85 - Assessment for order administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1000.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Administrative Assessment and Marketing Service Deduction § 1000.85...

  1. 29 CFR 1978.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the Administrative Review Board. 1978.110 Section 1978.110 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISION OF...

  2. 29 CFR 1978.110 - Decisions and orders of the Administrative Review Board.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decisions and orders of the Administrative Review Board. 1978.110 Section 1978.110 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISION...

  3. 29 CFR 1986.109 - Decisions and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decisions and orders of the administrative law judge. 1986.109 Section 1986.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISION OF...

  4. 29 CFR 1986.110 - Decisions and orders of the Administrative Review Board.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decisions and orders of the Administrative Review Board. 1986.110 Section 1986.110 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISION...

  5. 29 CFR 1978.109 - Decisions and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decisions and orders of the administrative law judge. 1978.109 Section 1978.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISION OF...

  6. 29 CFR 801.67 - Decision and Order of Administrative Law Judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Decision and Order of Administrative Law Judge. 801.67 Section 801.67 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative...

  7. 29 CFR 801.67 - Decision and Order of Administrative Law Judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Decision and Order of Administrative Law Judge. 801.67 Section 801.67 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative...

  8. 29 CFR 801.67 - Decision and Order of Administrative Law Judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Decision and Order of Administrative Law Judge. 801.67 Section 801.67 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative...

  9. 29 CFR 801.67 - Decision and Order of Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Decision and Order of Administrative Law Judge. 801.67 Section 801.67 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative...

  10. 29 CFR 801.67 - Decision and Order of Administrative Law Judge.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Decision and Order of Administrative Law Judge. 801.67 Section 801.67 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative...

  11. 29 CFR 500.262 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Decision and order of Administrative Law Judge. 500.262 Section 500.262 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings...

  12. 29 CFR 500.262 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Decision and order of Administrative Law Judge. 500.262 Section 500.262 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings...

  13. 19 CFR 356.30 - Sanctions for violations of a protective order for privileged information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Sanctions for violations of a protective order for privileged information. 356.30 Section 356.30 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.30 Sanctions for violations of...

  14. 19 CFR 356.30 - Sanctions for violations of a protective order for privileged information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Sanctions for violations of a protective order for privileged information. 356.30 Section 356.30 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.30 Sanctions for violations of...

  15. 19 CFR 356.12 - Sanctions for violation of a protective order or disclosure undertaking.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Sanctions for violation of a protective order or disclosure undertaking. 356.12 Section 356.12 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.12 Sanctions for violation of...

  16. 19 CFR 356.12 - Sanctions for violation of a protective order or disclosure undertaking.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Sanctions for violation of a protective order or disclosure undertaking. 356.12 Section 356.12 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.12 Sanctions for violation of...

  17. 19 CFR 356.30 - Sanctions for violations of a protective order for privileged information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Sanctions for violations of a protective order for privileged information. 356.30 Section 356.30 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.30 Sanctions for violations of...

  18. 19 CFR 356.12 - Sanctions for violation of a protective order or disclosure undertaking.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Sanctions for violation of a protective order or disclosure undertaking. 356.12 Section 356.12 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.12 Sanctions for violation of...

  19. 19 CFR 356.30 - Sanctions for violations of a protective order for privileged information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Sanctions for violations of a protective order for privileged information. 356.30 Section 356.30 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.30 Sanctions for violations of...

  20. 19 CFR 356.30 - Sanctions for violations of a protective order for privileged information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Sanctions for violations of a protective order for privileged information. 356.30 Section 356.30 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.30 Sanctions for violations of...

  1. 19 CFR 356.12 - Sanctions for violation of a protective order or disclosure undertaking.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Sanctions for violation of a protective order or disclosure undertaking. 356.12 Section 356.12 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.12 Sanctions for violation of...

  2. 19 CFR 356.12 - Sanctions for violation of a protective order or disclosure undertaking.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Sanctions for violation of a protective order or disclosure undertaking. 356.12 Section 356.12 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT... AGREEMENT Violation of a Protective Order or a Disclosure Undertaking § 356.12 Sanctions for violation of...

  3. 7 CFR 1005.85 - Assessment for order administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Assessment for order administration. 1005.85 Section 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE...

  4. 7 CFR 1005.85 - Assessment for order administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Assessment for order administration. 1005.85 Section 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE...

  5. 7 CFR 1005.85 - Assessment for order administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Assessment for order administration. 1005.85 Section 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE...

  6. 7 CFR 1005.85 - Assessment for order administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Assessment for order administration. 1005.85 Section 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE...

  7. 7 CFR 1005.85 - Assessment for order administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Assessment for order administration. 1005.85 Section 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE...

  8. 49 CFR 1104.14 - Protective orders to maintain confidentiality.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-SERVICE-PLEADINGS, GENERALLY § 1104.14 Protective orders to maintain confidentiality. (a) Segregation of... 49 Transportation 8 2010-10-01 2010-10-01 false Protective orders to maintain confidentiality... on the outside “Confidential materials subject to a request for a protective order.” (b) Requests...

  9. 49 CFR 1104.14 - Protective orders to maintain confidentiality.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-SERVICE-PLEADINGS, GENERALLY § 1104.14 Protective orders to maintain confidentiality. (a) Segregation of... 49 Transportation 8 2011-10-01 2011-10-01 false Protective orders to maintain confidentiality... on the outside “Confidential materials subject to a request for a protective order.” (b) Requests...

  10. 12 CFR Appendix A to Subpart C of... - Model Stipulation for Protective Order and Model Protective Order

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Model Stipulation for Protective Order and Model Protective Order A Appendix A to Subpart C of Part 4 Banks and Banking COMPTROLLER OF THE CURRENCY... Pt. 4, Subpt. C, App. A Appendix A to Subpart C of Part 4—Model Stipulation for Protective Order...

  11. 12 CFR Appendix A to Subpart C of... - Model Stipulation for Protective Order and Model Protective Order

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Model Stipulation for Protective Order and Model Protective Order A Appendix A to Subpart C of Part 4 Banks and Banking COMPTROLLER OF THE CURRENCY... Pt. 4, Subpt. C, App. A Appendix A to Subpart C of Part 4—Model Stipulation for Protective Order...

  12. 12 CFR Appendix A to Subpart C of... - Model Stipulation for Protective Order and Model Protective Order

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Model Stipulation for Protective Order and Model Protective Order A Appendix A to Subpart C of Part 4 Banks and Banking COMPTROLLER OF THE CURRENCY... Pt. 4, Subpt. C, App. A Appendix A to Subpart C of Part 4—Model Stipulation for Protective Order...

  13. Administrator Tenure Statutes and Other Legislative Protection of Position.

    ERIC Educational Resources Information Center

    Gluckman, Ivan

    1983-01-01

    A pamphlet reviewing the employment rights of school administrators in each state, this report distinguishes between substantive and procedural rights for administrators threatened with demotion or dismissal. The author argues that principals should be aware of the kind and degree of statutory employment protection in their states, which differ in…

  14. 29 CFR 24.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Decision and orders of the Administrative Review Board. 24.110 Section 24.110 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF...

  15. 29 CFR 24.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Decision and orders of the Administrative Review Board. 24.110 Section 24.110 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF...

  16. 29 CFR 24.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Decision and orders of the Administrative Review Board. 24.110 Section 24.110 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF...

  17. 29 CFR 24.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Decision and orders of the Administrative Review Board. 24.110 Section 24.110 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF...

  18. 37 CFR 404.12 - Protection and administration of inventions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of inventions. 404.12 Section 404.12 Patents, Trademarks, and Copyrights ASSISTANT SECRETARY FOR TECHNOLOGY POLICY, DEPARTMENT OF COMMERCE LICENSING OF GOVERNMENT-OWNED INVENTIONS § 404.12 Protection and administration of inventions. A Federal agency may take any suitable and necessary steps to protect...

  19. 37 CFR 404.12 - Protection and administration of inventions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of inventions. 404.12 Section 404.12 Patents, Trademarks, and Copyrights ASSISTANT SECRETARY FOR TECHNOLOGY POLICY, DEPARTMENT OF COMMERCE LICENSING OF GOVERNMENT OWNED INVENTIONS § 404.12 Protection and administration of inventions. A Federal agency may take any suitable and necessary steps to protect...

  20. 37 CFR 404.12 - Protection and administration of inventions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of inventions. 404.12 Section 404.12 Patents, Trademarks, and Copyrights ASSISTANT SECRETARY FOR TECHNOLOGY POLICY, DEPARTMENT OF COMMERCE LICENSING OF GOVERNMENT OWNED INVENTIONS § 404.12 Protection and administration of inventions. A Federal agency may take any suitable and necessary steps to protect...

  1. 14 CFR 17.9 - Protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... a competitive advantage to one or more firms. (b) The terms of the Office of Dispute Resolution for... application shall establish that the applicant is not involved in competitive decisionmaking for any firm that could gain a competitive advantage from access to the protected information and that the applicant...

  2. 41 CFR 105-70.024 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... justice requires to protect a party or person from annoyance, embarrassment, oppression, or undue burden..., commercial information, or facts pertaining to any criminal investigation, proceeding, or other... Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General...

  3. 25 CFR 11.1208 - Service of the protection order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Service of the protection order. 11.1208 Section 11.1208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1208 Service of...

  4. 25 CFR 11.1208 - Service of the protection order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Service of the protection order. 11.1208 Section 11.1208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1208 Service of...

  5. 25 CFR 11.1208 - Service of the protection order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Service of the protection order. 11.1208 Section 11.1208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1208 Service of...

  6. 25 CFR 11.1208 - Service of the protection order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Service of the protection order. 11.1208 Section 11.1208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1208 Service of...

  7. 25 CFR 11.1208 - Service of the protection order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Service of the protection order. 11.1208 Section 11.1208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1208 Service of...

  8. 45 CFR 681.22 - Are protective orders available?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Procedures § 681.22 Are protective orders available... confidential research, development, commercial information, or facts pertaining to any criminal...

  9. 45 CFR 681.22 - Are protective orders available?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Procedures § 681.22 Are protective orders available... confidential research, development, commercial information, or facts pertaining to any criminal...

  10. 45 CFR 681.22 - Are protective orders available?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Procedures § 681.22 Are protective orders available... confidential research, development, commercial information, or facts pertaining to any criminal...

  11. 45 CFR 681.22 - Are protective orders available?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Procedures § 681.22 Are protective orders available... confidential research, development, commercial information, or facts pertaining to any criminal...

  12. 28 CFR 68.52 - Final order of the Administrative Law Judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Final order of the Administrative Law... FRAUD § 68.52 Final order of the Administrative Law Judge. (a) Proposed final order. (1) Within twenty... Administrative Law Judge may, by order, require that when a proposed order is filed for the Administrative...

  13. 24 CFR 180.640 - In camera and protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false In camera and protective orders. 180.640 Section 180.640 Housing and Urban Development Regulations Relating to Housing and Urban... at Hearing § 180.640 In camera and protective orders. The ALJ may limit discovery or the...

  14. 24 CFR 180.640 - In camera and protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false In camera and protective orders. 180.640 Section 180.640 Housing and Urban Development Regulations Relating to Housing and Urban... at Hearing § 180.640 In camera and protective orders. The ALJ may limit discovery or the...

  15. 24 CFR 180.640 - In camera and protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false In camera and protective orders. 180.640 Section 180.640 Housing and Urban Development Regulations Relating to Housing and Urban... at Hearing § 180.640 In camera and protective orders. The ALJ may limit discovery or the...

  16. 24 CFR 180.640 - In camera and protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false In camera and protective orders. 180.640 Section 180.640 Housing and Urban Development Regulations Relating to Housing and Urban... at Hearing § 180.640 In camera and protective orders. The ALJ may limit discovery or the...

  17. 45 CFR 2554.30 - Are protective orders available?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Are protective orders available? 2554.30 Section 2554.30 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 2554.30 Are protective orders available? (a) A party or...

  18. 45 CFR 2554.30 - Are protective orders available?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Are protective orders available? 2554.30 Section 2554.30 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 2554.30 Are protective orders available? (a) A party or...

  19. 24 CFR 180.640 - In camera and protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false In camera and protective orders. 180.640 Section 180.640 Housing and Urban Development Regulations Relating to Housing and Urban... at Hearing § 180.640 In camera and protective orders. The ALJ may limit discovery or the...

  20. Protection Orders Protect against Assault and Injury: A Longitudinal Study of Police-Involved Women Victims of Intimate Partner Violence

    ERIC Educational Resources Information Center

    Kothari, Catherine L.; Rhodes, Karin V.; Wiley, James A.; Fink, Jeffrey; Overholt, Scott; Dichter, Melissa E.; Marcus, Steven C.; Cerulli, Catherine

    2012-01-01

    The objective of this study was to measure the efficacy of protection orders (POs) in reducing assault and injury-related outcomes using a matched comparison group and tracking outcomes over time. This study was a retrospective review of police, emergency department, family court, and prosecutor administrative records for a cohort of…

  1. 12 CFR Appendix A to Subpart C of... - Model Stipulation for Protective Order and Model Protective Order

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Model Stipulation for Protective Order and Model Protective Order A Appendix A to Subpart C of Part 4 Banks and Banking COMPTROLLER OF THE CURRENCY... Ratios for an Individual Bank Pt. 4, Subpt. C, App. A Appendix A to Subpart C of Part 4—Model...

  2. 37 CFR 404.12 - Protection and administration of inventions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of inventions. 404.12 Section 404.12 Patents, Trademarks, and Copyrights NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE LICENSING OF GOVERNMENT-OWNED INVENTIONS § 404.12 Protection and administration of inventions. A Federal agency may take any suitable and necessary steps...

  3. 37 CFR 404.12 - Protection and administration of inventions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of inventions. 404.12 Section 404.12 Patents, Trademarks, and Copyrights NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE LICENSING OF GOVERNMENT-OWNED INVENTIONS § 404.12 Protection and administration of inventions. A Federal agency may take any suitable and necessary steps...

  4. 76 FR 81929 - San Fernando Valley Area 2; Notice of Proposed Administrative Order on Consent Re: 4057 and 4059...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY San Fernando Valley Area 2; Notice of Proposed Administrative Order on Consent Re: 4057 and 4059 Goodwin Avenue, Los Angeles, CA AGENCY: Environmental Protection Agency (EPA). ACTION: Notice; request...

  5. 45 CFR 2554.30 - Are protective orders available?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 2554.30 Are protective... being sealed be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  6. 45 CFR 2554.30 - Are protective orders available?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 2554.30 Are protective... being sealed be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  7. 45 CFR 2554.30 - Are protective orders available?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 2554.30 Are protective... being sealed be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  8. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED... Investigations for Relief From Market Disruption § 206.47 Limited disclosure of certain confidential...

  9. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED... Investigations For Action in Response to Trade Diversion; Reviews of Action Taken § 206.66 Limited disclosure...

  10. 19 CFR 206.37 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.37 Section 206.37 Customs Duties UNITED... Investigations Relating to Bilateral Safeguard Actions § 206.37 Limited disclosure of certain...

  11. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential business... confidential business information properly disclosed pursuant to this section for the purpose of...

  12. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential business... confidential business information properly disclosed pursuant to this section for the purpose of...

  13. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential business... confidential business information properly disclosed pursuant to this section for the purpose of...

  14. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential business... confidential business information properly disclosed pursuant to this section for the purpose of...

  15. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential business... confidential business information properly disclosed pursuant to this section for the purpose of...

  16. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO...

  17. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO...

  18. Outcomes of Civil Protective Orders: Results from One State

    ERIC Educational Resources Information Center

    Diviney, Charles L.; Parekh, Asha; Olson, Lenora M.

    2009-01-01

    This study compares final sentencing decisions ordered by judges to federal and state sentencing guidelines for protective order violations. The authors reviewed violations that were pled before the largest district court in Utah and found that in the majority of cases, defendants were not sentenced in accordance with federal and state guidelines.…

  19. 28 CFR 68.52 - Final order of the Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administrative Law Judge may allow, the Administrative Law Judge may require the parties to file proposed... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Final order of the Administrative Law... AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE ADMINISTRATIVE LAW JUDGES IN CASES...

  20. Outcomes of civil protective orders: results from one state.

    PubMed

    Diviney, Charles L; Parekh, Asha; Olson, Lenora M

    2009-07-01

    This study compares final sentencing decisions ordered by judges to federal and state sentencing guidelines for protective order violations. The authors reviewed violations that were pled before the largest district court in Utah and found that in the majority of cases, defendants were not sentenced in accordance with federal and state guidelines. Although state guidelines mandate defendants who violate a protective order to attend a batterer intervention program, less than one fourth of defendants were sentenced to attend such programs. Fewer than half of the defendants were arrested and incarcerated, as opposed to the 100% mandated by state sentencing guidelines. Federal guidelines mandate that all defendants be ordered to surrender firearms, but only six defendants were given that order. This study shows that the judicial system could be more aggressive in improving the safety of victims of intimate partner violence by using the full extent of the sentencing guidelines. PMID:18701748

  1. Layered virus protection for the operations and administrative messaging system

    NASA Technical Reports Server (NTRS)

    Cortez, R. H.

    2002-01-01

    NASA's Deep Space Network (DSN) is critical in supporting the wide variety of operating and plannedunmanned flight projects. For day-to-day operations it relies on email communication between the three Deep Space Communication Complexes (Canberra, Goldstone, Madrid) and NASA's Jet Propulsion Laboratory. The Operations & Administrative Messaging system, based on the Microsoft Windows NTand Exchange platform, provides the infrastructure that is required for reliable, mission-critical messaging. The reliability of this system, however, is threatened by the proliferation of email viruses that continue to spread at alarming rates. A layered approach to email security has been implemented across the DSN to protect against this threat.

  2. Civil Protective Order Outcomes: Violations and Perceptions of Effectiveness

    ERIC Educational Resources Information Center

    Logan, T. K.; Walker, Robert

    2009-01-01

    This study examined protective order (PO) outcomes for a period of 12 months for 698 women from multiple jurisdictions. Overall, results indicate that 2 out of 5 women did not experience violence after the PO was issued; however, 3 out of 5 women did experience ongoing violence. Two key risk factors were associated with PO violations and are…

  3. 32 CFR 635.29 - Domestic violence and protection orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Domestic violence and protection orders. 635.29... ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.29 Domestic violence... permitted by law and regulation. AR 608-18 contains additional information about domestic violence...

  4. 32 CFR 635.29 - Domestic violence and protection orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Domestic violence and protection orders. 635.29... ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.29 Domestic violence... permitted by law and regulation. AR 608-18 contains additional information about domestic violence...

  5. 32 CFR 635.29 - Domestic violence and protection orders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Domestic violence and protection orders. 635.29... ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.29 Domestic violence... permitted by law and regulation. AR 608-18 contains additional information about domestic violence...

  6. 32 CFR 635.29 - Domestic violence and protection orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Domestic violence and protection orders. 635.29... ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.29 Domestic violence... permitted by law and regulation. AR 608-18 contains additional information about domestic violence...

  7. 31 CFR 501.733 - Evidence: confidential information, protective orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Evidence: confidential information, protective orders. 501.733 Section 501.733 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY REPORTING, PROCEDURES...

  8. 31 CFR 501.733 - Evidence: confidential information, protective orders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Evidence: confidential information, protective orders. 501.733 Section 501.733 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY REPORTING, PROCEDURES...

  9. 31 CFR 501.733 - Evidence: confidential information, protective orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evidence: confidential information, protective orders. 501.733 Section 501.733 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY REPORTING, PROCEDURES...

  10. 31 CFR 501.733 - Evidence: confidential information, protective orders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Evidence: confidential information, protective orders. 501.733 Section 501.733 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY REPORTING, PROCEDURES...

  11. 31 CFR 501.733 - Evidence: confidential information, protective orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Evidence: confidential information, protective orders. 501.733 Section 501.733 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY REPORTING, PROCEDURES...

  12. 17 CFR 242.611 - Order protection rule.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Order protection rule. 242.611 Section 242.611 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation...

  13. 77 FR 56639 - Bonneville Power Administration; Notice of Petition for Declaratory Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Energy Regulatory Commission Bonneville Power Administration; Notice of Petition for Declaratory Order... Bonneville Power Administration (Bonneville), submitted certain amendments to its Open Access Transmission Tariff (tariff) and a Petition for Declaratory Order requesting the Commission find that...

  14. Review of orders and regulations requiring environmental protection

    SciTech Connect

    Kelly, E.; Cunningham, R.; Michael, D.

    1996-09-01

    With the increased awareness of and interest in potential ecological risks associated with past, current, and future Department of Energy (DOE) activities, DOE`s Defense Programs (DP) Office of Technical and Environmental Support sponsored a study to (1) evaluate the effectiveness of the current compliance-driven environmental protection and assessment efforts relative to ecological concerns; (2) explore the need for a more focused, integrated approach to address ecological impacts; and (3) identify the requirements for an integrated approach. The study explored four questions. (a) Which federal regulations and DOE orders either explicitly require ecological assessments or implicitly require them through environmental protection language? (b) What currently is being done at selected DOE facilities to implement these regulations and orders? (c) What are private sector industries doing in terms of ecological risk assessments and how do industry approaches and issues compare with those of DOE? (d) What, if anything, in addition to current efforts is needed to ensure the protection of ecological resources associated with DOE facilities, to support defensible decision making, and to improve efficiency? The results of this study are presented in a report titled {open_quotes}Integrated, Comprehensive Ecological Impact Assessments In Support of Department of Energy Decision Making{close_quotes}. This report is a companion document to that report. This report provides a more detailed discussion of the document reviews of the relevant environmental protection regulations and current and pending DOE orders. The main goal of the document reviews was to understand existing requirements for ecological data collection and impact assessments.

  15. 29 CFR 24.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Decision and orders of the administrative law judge. 24.109... administrative law judge. (a) The decision of the administrative law judge will contain appropriate findings... with an investigation is subject to review by the administrative law judge, and a complaint may not...

  16. 20 CFR 726.313 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Decision and order of Administrative Law... COAL MINE OPERATOR'S INSURANCE Civil Money Penalties § 726.313 Decision and order of Administrative Law Judge. (a) The Administrative Law Judge shall render a decision on the issues referred by the...

  17. 20 CFR 655.1040 - Decision and order of administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... subpart J of this part), the administrative law judge shall not determine the prevailing wage rate de novo... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Decision and order of administrative law... and order of administrative law judge. (a) Within 90 calendar days after receipt of the transcript...

  18. 28 CFR 541.27 - Protection case-placement in Administrative Detention status.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Protection case-placement in Administrative Detention status. 541.27 Section 541.27 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT INMATE DISCIPLINE AND SPECIAL HOUSING UNITS Special Housing Units § 541.27 Protection case—placement...

  19. Universal service order; protective order for non-rural local exchange carriers--FCC. Policy statement.

    PubMed

    1998-08-11

    This protective order for non-rural local exchange carriers (LECs) is intended to facilitate and expedite review of documents containing trade secrets and commercial or financial information submitted by a person or entity that are either privileged or confidential. It reflects the manner in which "Confidential Information," as that term is defined herein, is to be treated in the universal service proceeding to select a mechanism to determine high cost support. The Order is not intended to constitute a resolution of the merits concerning whether any Confidential Information would be released publicly by the Commission upon a proper request. PMID:10182564

  20. Symmetry-protected topologically ordered states for universal quantum computation

    NASA Astrophysics Data System (ADS)

    Poulsen Nautrup, Hendrik; Wei, Tzu-Chieh

    Measurement-based quantum computation (MBQC) is a model for quantum information processing utilizing only local measurements on suitably entangled resource states for the implementation of quantum gates. A complete characterization for universal resource states is still missing. It has been shown that symmetry-protected topological order (SPTO) in one dimension can be exploited for the protection of certain quantum gates in MBQC. Here we investigate whether any 2D nontrivial SPTO states can serve as resource for MBQC. In particular, we show that the nontrivial SPTO ground state of the CZX model on the square lattice by Chen et al. [Phys. Rev. B 84, 235141 (2011)] can be reduced to a 2D cluster state by local measurement, hence a universal resource state. Such ground states have been generalized to qudits with symmetry action described by three cocycles of a finite group G of order d and shown to exhibit nontrivial SPTO. We also extend these to arbitary lattices and show that the generalized two-dimensional plaquette states on arbitrary lattices exhibit nontrivial SPTO in terms of symmetry fractionalization and that they are universal resource states for quantum computation. SPTO states therefore can provide a new playground for measurement-based quantum computation. This work was supported in part by the National Science Foundation.

  1. Early Administration of Carvedilol Protected against Doxorubicin-Induced Cardiomyopathy.

    PubMed

    Chen, Yung-Lung; Chung, Sheng-Ying; Chai, Han-Tan; Chen, Chih-Hung; Liu, Chu-Feng; Chen, Yi-Ling; Huang, Tien-Hung; Zhen, Yen-Yi; Sung, Pei-Hsun; Sun, Cheuk-Kwan; Chua, Sarah; Lu, Hung-I; Lee, Fan-Yen; Sheu, Jiunn-Jye; Yip, Hon-Kan

    2015-12-01

    This study tested for the benefits of early administration of carvedilol as protection against doxorubicin (DOX)-induced cardiomyopathy. Thirty male, adult B6 mice were categorized into group 1 (untreated control), group 2 [DOX treatment (15 mg/every other day for 2 weeks, i.p.], and group 3 [carvedilol (15 mg/kg/d, from day 7 after DOX treatment for 28 days)], and euthanized by day 35 after DOX treatment. By day 35, the left ventricular ejection fraction (LVEF) was significantly lower in group 2 than in groups 1 and 3, and significantly lower in group 3 than in group 1, whereas the left ventricular (LV) end-diastolic and LV end-systolic dimensions showed an opposite pattern to the LVEF among the three groups. The protein expressions of fibrotic (Smad3, TGF-β), apoptotic (BAX, cleaved caspase 3, PARP), DNA damage (γ-H2AX), oxidative stress (oxidized protein), mitochondrial damage (cytosolic cytochrome-C), heart failure (brain natriuretic peptide), and hypertrophic (β-MHC) biomarkers of the LV myocardium showed an opposite pattern to the LVEF among the three groups. The protein expressions of antifibrotic (BMP-2, Smad1/5), α-MHC, and phosphorylated-Akt showed an identical pattern to the LVEF among the three groups. The microscopic findings of fibrotic and collagen-deposition areas and the numbers of γ-H2AX(+) and 53BP1(+) cells in the LV myocardium exhibited an opposite pattern, whereas the numbers of endothelial cell (CD31(+), vWF(+)) markers showed an identical pattern to the LVEF among the three groups. Cardiac stem cell markers (C-kit(+) and Sca-1(+) cells) were significantly and progressively increased from group 1 to group 3. Additionally, the in vitro study showed carvedilol treatment significantly inhibited DOX-induced cardiomyoblast DNA (CD90/XRCC1(+), CD90/53BP1(+), and r-H2AX(+) cells) damage. Early carvedilol therapy protected against DOX-induced DNA damage and cardiomyopathy. PMID:26511374

  2. 20 CFR 422.440 - What are your employer's responsibilities under an administrative wage garnishment order?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false What are your employer's responsibilities under an administrative wage garnishment order? 422.440 Section 422.440 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by Administrative Wage...

  3. 20 CFR 422.440 - What are your employer's responsibilities under an administrative wage garnishment order?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false What are your employer's responsibilities under an administrative wage garnishment order? 422.440 Section 422.440 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by Administrative Wage...

  4. 20 CFR 422.440 - What are your employer's responsibilities under an administrative wage garnishment order?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false What are your employer's responsibilities under an administrative wage garnishment order? 422.440 Section 422.440 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by Administrative Wage...

  5. 20 CFR 422.440 - What are your employer's responsibilities under an administrative wage garnishment order?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false What are your employer's responsibilities under an administrative wage garnishment order? 422.440 Section 422.440 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by Administrative Wage...

  6. 20 CFR 422.440 - What are your employer's responsibilities under an administrative wage garnishment order?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false What are your employer's responsibilities under an administrative wage garnishment order? 422.440 Section 422.440 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by Administrative Wage...

  7. 75 FR 9869 - Initiation of Administrative Review of the Antidumping Duty Order on Wooden Bedroom Furniture...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ...The Department of Commerce (the Department) has received requests to conduct an administrative review of the antidumping duty order on wooden bedroom furniture from the People's Republic of China (PRC). The anniversary month of this order is January. In accordance with the Department's regulations, we are initiating this administrative...

  8. 77 FR 33235 - Public Land Order No. 7789; Partial Withdrawal Revocation and Transfer of Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... Bureau of Land Management Public Land Order No. 7789; Partial Withdrawal Revocation and Transfer of Administrative Jurisdiction for Fort Vancouver National Historic Site, WA AGENCY: Bureau of Land Management... it was withdrawn. This order also transfers administrative jurisdiction of the land to the...

  9. 78 FR 24774 - Public Land Order No. 7813; Withdrawal Modification and Transfer of Administrative Jurisdiction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ... Bureau of Land Management Public Land Order No. 7813; Withdrawal Modification and Transfer of Administrative Jurisdiction; Montana AGENCY: Bureau of Land Management, Interior. ACTION: Public Land Order..., it is ordered as follows: Public Land Order No. 1843 (24 FR 3729 (1959)), which withdrew...

  10. Classifying gauge anomalies through symmetry-protected trivial orders and classifying gravitational anomalies through topological orders

    NASA Astrophysics Data System (ADS)

    Wen, Xiao-Gang

    2013-08-01

    In this paper, we systematically study gauge anomalies in bosonic and fermionic weak-coupling gauge theories with gauge group G (which can be continuous or discrete) in d space-time dimensions. We show a very close relation between gauge anomalies for gauge group G and symmetry-protected trivial (SPT) orders (also known as symmetry-protected topological (SPT) orders) with symmetry group G in one-higher dimension. The SPT phases are classified by group cohomology class Hd+1(G,R/Z). Through a more careful consideration, we argue that the gauge anomalies are described by the elements in Free[Hd+1(G,R/Z)]⊕Hπ˙d+1(BG,R/Z). The well known Adler-Bell-Jackiw anomalies are classified by the free part of Hd+1(G,R/Z) (denoted as Free[Hd+1(G,R/Z)]). We refer to other kinds of gauge anomalies beyond Adler-Bell-Jackiw anomalies as non-ABJ gauge anomalies, which include Witten SU(2) global gauge anomalies. We introduce a notion of π-cohomology group, Hπ˙d+1(BG,R/Z), for the classifying space BG, which is an Abelian group and include Tor[Hd+1(G,R/Z)] and topological cohomology group Hd+1(BG,R/Z) as subgroups. We argue that Hπ˙d+1(BG,R/Z) classifies the bosonic non-ABJ gauge anomalies and partially classifies fermionic non-ABJ anomalies. Using the same approach that shows gauge anomalies to be connected to SPT phases, we can also show that gravitational anomalies are connected to topological orders (i.e., patterns of long-range entanglement) in one-higher dimension.

  11. 29 CFR 1979.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1979.109 Section 1979.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 519 OF THE WENDELL H....

  12. 29 CFR 1982.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1982.109 Section 1982.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE NATIONAL TRANSIT SYSTEMS SECURITY...

  13. 29 CFR 1983.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 1983.109 Section 1983.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 219 OF THE CONSUMER PRODUCT...

  14. 29 CFR 1980.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1980.109 Section 1980.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 806 OF THE SARBANES-OXLEY ACT...

  15. 29 CFR 1984.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1984.109 Section 1984.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 1558 OF THE AFFORDABLE CARE...

  16. 29 CFR 1979.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 1979.109 Section 1979.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 519 OF THE WENDELL H....

  17. 29 CFR 1979.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Decision and orders of the administrative law judge. 1979.109 Section 1979.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 519 OF THE WENDELL H....

  18. 29 CFR 1982.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 1982.109 Section 1982.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE NATIONAL TRANSIT SYSTEMS SECURITY...

  19. 29 CFR 1980.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 1980.109 Section 1980.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 806 OF THE SARBANES-OXLEY ACT...

  20. 29 CFR 1983.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1983.109 Section 1983.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 219 OF THE CONSUMER PRODUCT...

  1. 29 CFR 1981.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 1981.109 Section 1981.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 6 OF THE PIPELINE...

  2. 29 CFR 1981.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Decision and orders of the administrative law judge. 1981.109 Section 1981.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 6 OF THE PIPELINE...

  3. 29 CFR 1981.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 1981.109 Section 1981.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 6 OF THE PIPELINE...

  4. 46 CFR 201.3 - Authentication of rules, orders, determinations and decisions of the Administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Authentication of rules, orders, determinations and decisions of the Administration. 201.3 Section 201.3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION POLICY, PRACTICE AND PROCEDURE RULES OF PRACTICE AND PROCEDURE General Information (Rule 1) § 201.3 Authentication of rules,...

  5. 29 CFR 24.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Decision and orders of the administrative law judge. 24.109... administrative law judge. (a) The decision of the ALJ will contain appropriate findings, conclusions, and an... and circumstances warrant. (d)(1) If the ALJ concludes that the respondent has violated the law,...

  6. 29 CFR 24.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Decision and orders of the administrative law judge. 24.109... administrative law judge. (a) The decision of the ALJ will contain appropriate findings, conclusions, and an... and circumstances warrant. (d)(1) If the ALJ concludes that the respondent has violated the law,...

  7. 29 CFR 24.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Decision and orders of the administrative law judge. 24.109... administrative law judge. (a) The decision of the ALJ will contain appropriate findings, conclusions, and an... and circumstances warrant. (d)(1) If the ALJ concludes that the respondent has violated the law,...

  8. 29 CFR 24.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Decision and orders of the administrative law judge. 24.109... administrative law judge. (a) The decision of the ALJ will contain appropriate findings, conclusions, and an... and circumstances warrant. (d)(1) If the ALJ concludes that the respondent has violated the law,...

  9. Rank-Order Distribution of Administrative Salaries Paid, 1985-86. Nineteenth Annual Report.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Results of a survey of salaries of full-time administrators at public, doctoral-granting institutions for 1985-1986 are presented. Rank order distributions of 12-month administrative salaries are provided for 156 state universities in 49 states and 33 university systems in 27 states. Salary data for 151 universities in 47 states are also arranged…

  10. Rank-Order Distribution of Administrative Salaries Paid, 1986-87. Twentieth Annual Report.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Results of a survey of salaries of full-time administrators at public, doctoral-granting institutions for 1986-1987 are presented. Rank order distributions of 12-month administrative salaries are provided for 151 state universities in 49 states and 29 university systems in 23 states. Salary data for 151 universities are also arranged into the nine…

  11. 4 CFR 22.25 - Protective Orders and In Camera Review [Rule 25].

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 4 Accounts 1 2011-01-01 2011-01-01 false Protective Orders and In Camera Review . 22.25 Section 22... ACCOUNTABILITY OFFICE CONTRACT APPEALS BOARD § 22.25 Protective Orders and In Camera Review . (a) Protective... specified in an order of the Board. (b) In camera review. Generally, all documents and evidence provided...

  12. 4 CFR 22.25 - Protective Orders and In Camera Review [Rule 25].

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 4 Accounts 1 2012-01-01 2012-01-01 false Protective Orders and In Camera Review . 22.25 Section 22... ACCOUNTABILITY OFFICE CONTRACT APPEALS BOARD § 22.25 Protective Orders and In Camera Review . (a) Protective... specified in an order of the Board. (b) In camera review. Generally, all documents and evidence provided...

  13. 4 CFR 22.25 - Protective Orders and In Camera Review [Rule 25].

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 4 Accounts 1 2013-01-01 2013-01-01 false Protective Orders and In Camera Review . 22.25 Section 22... ACCOUNTABILITY OFFICE CONTRACT APPEALS BOARD § 22.25 Protective Orders and In Camera Review . (a) Protective... specified in an order of the Board. (b) In camera review. Generally, all documents and evidence provided...

  14. 4 CFR 22.25 - Protective Orders and In Camera Review [Rule 25].

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 4 Accounts 1 2014-01-01 2013-01-01 true Protective Orders and In Camera Review . 22.25 Section 22... ACCOUNTABILITY OFFICE CONTRACT APPEALS BOARD § 22.25 Protective Orders and In Camera Review . (a) Protective... specified in an order of the Board. (b) In camera review. Generally, all documents and evidence provided...

  15. 4 CFR 22.25 - Protective Orders and In Camera Review [Rule 25].

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Protective Orders and In Camera Review . 22.25 Section 22... ACCOUNTABILITY OFFICE CONTRACT APPEALS BOARD § 22.25 Protective Orders and In Camera Review . (a) Protective... specified in an order of the Board. (b) In camera review. Generally, all documents and evidence provided...

  16. 76 FR 78093 - Correction of Administrative Errors; Court Orders and Legal Processes Affecting Thrift Savings...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... payment pursuant to a retirement benefits court order. See 69 FR 18294 (April 7, 2004). The Agency...;having general applicability and legal effect, most of which are keyed #0;to and codified in the Code of... CFR Parts 1605 and 1653 Correction of Administrative Errors; Court Orders and Legal...

  17. 29 CFR 1987.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF THE FDA FOOD SAFETY MODERNIZATION ACT Litigation § 1987.109 Decision and orders of the... 29 Labor 9 2014-07-01 2014-07-01 false Decision and orders of the administrative law judge. 1987.109 Section 1987.109 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND...

  18. 77 FR 54608 - Public Land Order No. 7796; Partial Withdrawal Revocation and Transfer of Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Administrative Jurisdiction, Kirtland Air Force Base; New Mexico AGENCY: Bureau of Land Management, Interior..., 123 Stat. 1449 (2009), it is ordered as follows: ] 1. Public Land Order No. 995 (19 FR 5443 (1954... with Kirtland Air Force Base, is hereby revoked only insofar as it affects the following described...

  19. 32 CFR 635.29 - Domestic violence and protection orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... other offense code that may be appropriate for an incident. For example, a soldier strikes his or her... written lawful order issued by a commander that orders a soldier to avoid contact with his or her...

  20. 17 CFR 242.611 - Order protection rule.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms... NMS stocks that do not fall within an exception set forth in paragraph (b) of this section and, if... bid was priced higher than a protected offer in the NMS stock. (5) The transaction that...

  1. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United...

  2. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United...

  3. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United...

  4. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United...

  5. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United...

  6. 25 CFR 11.1210 - Duration and renewal of a regular protection order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Duration and renewal of a regular protection order. 11.1210 Section 11.1210 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures §...

  7. 25 CFR 11.1210 - Duration and renewal of a regular protection order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Duration and renewal of a regular protection order. 11.1210 Section 11.1210 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures §...

  8. 25 CFR 11.1206 - Obtaining a regular (non-emergency) order of protection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11... act of domestic violence occurred, the court may issue an order of protection. The order must meet the... committed the act of domestic violence to refrain from acts or threats of violence against the petitioner...

  9. 25 CFR 11.1210 - Duration and renewal of a regular protection order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Duration and renewal of a regular protection order. 11.1210 Section 11.1210 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures §...

  10. 25 CFR 11.1210 - Duration and renewal of a regular protection order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Duration and renewal of a regular protection order. 11.1210 Section 11.1210 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures §...

  11. 25 CFR 11.1206 - Obtaining a regular (non-emergency) order of protection.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11... act of domestic violence occurred, the court may issue an order of protection. The order must meet the... committed the act of domestic violence to refrain from acts or threats of violence against the petitioner...

  12. 25 CFR 11.1206 - Obtaining a regular (non-emergency) order of protection.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11... act of domestic violence occurred, the court may issue an order of protection. The order must meet the... committed the act of domestic violence to refrain from acts or threats of violence against the petitioner...

  13. 25 CFR 11.1206 - Obtaining a regular (non-emergency) order of protection.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11... act of domestic violence occurred, the court may issue an order of protection. The order must meet the... committed the act of domestic violence to refrain from acts or threats of violence against the petitioner...

  14. 25 CFR 11.1206 - Obtaining a regular (non-emergency) order of protection.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11... act of domestic violence occurred, the court may issue an order of protection. The order must meet the... committed the act of domestic violence to refrain from acts or threats of violence against the petitioner...

  15. 25 CFR 11.1210 - Duration and renewal of a regular protection order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Duration and renewal of a regular protection order. 11.1210 Section 11.1210 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures §...

  16. Metabolomic analysis revealed glycylglycine accumulation in astrocytes after methionine enkephalin administration exhibiting neuron protective effects.

    PubMed

    Zhao, Chungang; Du, Huijie; Xu, Li; Wang, Jiao; Tang, Ling; Cao, Yunfeng; Li, Chen; Wang, Qingjun; Liu, Yang; Shan, Fengping; Feng, Juan; Xu, Fang; Gao, Peng

    2015-11-10

    Owing to its unrevealed etiology, multiple sclerosis lacks specific therapies up to now. Experiential administration of methionine enkephalin (MENK) on mouse model improved disease manifestations to some extent. In order to gain more insight on the significance of MENK application, a capillary electrophoresis-mass spectrometry (CE-MS) technique was employed to profile intracellular metabolite fluctuation in 5 astrocytoma cell lines challenged by MENK. The processed data were first evaluated through a bioinformatic process to ensure their compatibility with the study aims and then subjected to multivariate analysis. The results indicated that MENK administration increased intracellular tyrosine, phenylalanine, methionine and glycylglycine. Exemplified by U87 cells, glycylglycine inhibited cell proliferation as well as MENK but it also decreased cell nitric oxide excretion which could not be evoked by MENK. The neuron protective effects were also mirrored by the increased expression of some genes related to remyelination. This study demonstrated CE-MS to be a promising tool for cell metabolomic analysis and benefited the therapeutic exploring of multiple sclerosis with respect to metabolism intervention. PMID:26163404

  17. Protecting the normal in order to better kill the cancer

    PubMed Central

    Liu, Bingya; Ezeogu, Lewis; Zellmer, Lucas; Yu, Baofa; Xu, Ningzhi; Joshua Liao, Dezhong

    2015-01-01

    Chemotherapy is the only option for oncologists when a cancer has widely spread to different body sites. However, almost all currently available chemotherapeutic drugs will eventually encounter resistance after their initial positive effect, mainly because cancer cells develop genetic alterations, collectively coined herein as mutations, to adapt to the therapy. Some patients may still respond to a second chemo drug, but few cases respond to a third one. Since it takes time for cancer cells to develop new mutations and then select those life-sustaining ones via clonal expansion, “run against time for mutations to emerge” should be a crucial principle for treatment of those currently incurable cancers. Since cancer cells constantly change to adapt to the therapy whereas normal cells are stable, it may be a better strategy to shift our focus from killing cancer cells per se to protecting normal cells from chemotherapeutic toxicity. This new strategy requires the development of new drugs that are nongenotoxic and can quickly, in just hours or days, kill cancer cells without leaving the still-alive cells with time to develop mutations, and that should have their toxicities confined to only one or few organs, so that specific protections can be developed and applied. PMID:26177855

  18. 78 FR 40140 - Proposed CERCLA Administrative Settlement Agreement and Order on Consent for the Mercury Refining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... AGENCY Proposed CERCLA Administrative Settlement Agreement and Order on Consent for the Mercury Refining... between EPA and Titan Wheel Corporation of Illinois (hereafter ``Titan'') pertaining to the Mercury.... Comments should be sent to the individual identified below and should reference the Mercury...

  19. 76 FR 53898 - Proposed Administrative Settlement Agreement and Order on Consent; In Re: Ely Copper Mine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... AGENCY Proposed Administrative Settlement Agreement and Order on Consent; In Re: Ely Copper Mine... concerning the Ely Copper Mine Superfund Site in Vershire, Vermont with the following settling party: Ely... e-mail at gardner.ann@epa.gov . Additional information on the Ely Copper Mine Superfund Site can...

  20. 20 CFR 726.313 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Decision and order of Administrative Law Judge. 726.313 Section 726.313 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG...

  1. Twenty-Ninth Annual Rank-Order Distribution of Administrative Salaries Paid, 1995-96.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    This report presents comparative data collected from 98 state-supported universities in 47 states, and 38 university systems representing 30 states, on the administrative salaries they paid in 1994-95. The salaries are presented in rank-order (from highest to lowest) to facilitate comparisons of a participant's relative standing with other…

  2. Twenty-Eighth Annual Rank-Order Distribution of Administrative Salaries Paid, 1994-95.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    This report presents comparative data collected from 103 state-supported universities or university systems in 47 states, and 38 university systems representing 30 states, on the administrative salaries they paid in 1994-95. The salaries are presented in rank-order (from highest to lowest) to facilitate comparisons of a participant's relative…

  3. Thirtieth Annual Rank-Order Distribution of Administrative Salaries Paid, 1996-97.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    This report presents comparative data collected from 87 state-supported universities in 45 states, and 27 university systems representing 21 states, on the administrative salaries they paid in 1996-97. The salaries are presented in rank-order (from highest to lowest) to facilitate comparisons of a participant's relative standing with other…

  4. Twenty-Seventh Annual Rank-Order Distribution of Administrative Salaries Paid, 1993-94.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    This study presents comparative data collected from 85 state-supported universities or university systems in 45 states, and 35 university systems representing 28 states on the administrative salaries they paid in 1993-94. The salaries are presented in rank-order (from highest to lowest) to facilitate comparisons of a particular position's salary…

  5. 20 CFR 726.313 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Decision and order of Administrative Law Judge. 726.313 Section 726.313 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG...

  6. 20 CFR 726.313 - Decision and order of Administrative Law Judge.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Decision and order of Administrative Law Judge. 726.313 Section 726.313 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG...

  7. Order of Conners' CPT-II Administration within a Cognitive Test Battery Influences ADHD Indices

    ERIC Educational Resources Information Center

    Erdodi, Laszlo A.; Lajiness-O'Neill, Renee; Saules, Karen K.

    2010-01-01

    Objective: To study the effect of administration sequence on Conner's continuous performance test (CPT-II) scores in clients requesting psychological assessment. It was hypothesized that when administered at the end rather than beginning of a test battery, the test scores will show higher symptom severity. If present, order effects may cause the…

  8. 77 FR 52021 - Proposed CERCLA Administrative Settlement Agreement and Order on Consent for the Mercury Refining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Comprehensive Environmental Response, Compensation, and Liability Act of 1980, as amended (``CERCLA''), notice... minimis administrative settlement agreement and order on consent pursuant to Section 122(g)(4) of CERCLA... Group, Inc., Genesys Regional Medical Center, Ingot Metal Company, Ltd., Purina Mills, LLC, Shred-A-...

  9. 29 CFR 1982.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OF THE 9/11 COMMISSION ACT OF 2007, AND THE FEDERAL RAILROAD SAFETY ACT, AS AMENDED BY SECTION 1521 OF THE IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Litigation § 1982.109 Decision... 29 Labor 9 2011-07-01 2011-07-01 false Decision and orders of the administrative law judge....

  10. 29 CFR 1982.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007, AND THE FEDERAL RAILROAD SAFETY ACT, AS AMENDED BY SECTION 1521 OF THE IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Litigation... 29 Labor 9 2014-07-01 2014-07-01 false Decision and orders of the Administrative Review...

  11. 29 CFR 1982.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF THE 9/11 COMMISSION ACT OF 2007, AND THE FEDERAL RAILROAD SAFETY ACT, AS AMENDED BY SECTION 1521 OF THE IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Litigation § 1982.109 Decision... 29 Labor 9 2014-07-01 2014-07-01 false Decision and orders of the administrative law judge....

  12. 29 CFR 1982.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007, AND THE FEDERAL RAILROAD SAFETY ACT, AS AMENDED BY SECTION 1521 OF THE IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Litigation... 29 Labor 9 2011-07-01 2011-07-01 false Decision and orders of the Administrative Review...

  13. 25 CFR 11.1202 - How to petition for an order of protection.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1202 How to petition for an order of protection. A victim of domestic violence, or the parent, guardian of a victim, or... the act of domestic violence. (b) The petitioner is not required to file for annulment, separation,...

  14. 25 CFR 11.1202 - How to petition for an order of protection.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1202 How to petition for an order of protection. A victim of domestic violence, or the parent, guardian of a victim, or... the act of domestic violence. (b) The petitioner is not required to file for annulment, separation,...

  15. 25 CFR 11.1202 - How to petition for an order of protection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1202 How to petition for an order of protection. A victim of domestic violence, or the parent, guardian of a victim, or... the act of domestic violence. (b) The petitioner is not required to file for annulment, separation,...

  16. 25 CFR 11.1202 - How to petition for an order of protection.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1202 How to petition for an order of protection. A victim of domestic violence, or the parent, guardian of a victim, or... the act of domestic violence. (b) The petitioner is not required to file for annulment, separation,...

  17. 19 CFR 210.34 - Protective orders; reporting requirement; sanctions and other actions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...; sanctions and other actions. 210.34 Section 210.34 Customs Duties UNITED STATES INTERNATIONAL TRADE...) Issuance of protective order. Upon motion by a party or by the person from whom discovery is sought or by... judge may make any order that may appear necessary and appropriate for the protection of the...

  18. 19 CFR 210.34 - Protective orders; reporting requirement; sanctions and other actions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...; sanctions and other actions. 210.34 Section 210.34 Customs Duties UNITED STATES INTERNATIONAL TRADE...) Issuance of protective order. Upon motion by a party or by the person from whom discovery is sought or by... judge may make any order that may appear necessary and appropriate for the protection of the...

  19. 19 CFR 210.34 - Protective orders; reporting requirement; sanctions and other actions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...; sanctions and other actions. 210.34 Section 210.34 Customs Duties UNITED STATES INTERNATIONAL TRADE...) Issuance of protective order. Upon motion by a party or by the person from whom discovery is sought or by... judge may make any order that may appear necessary and appropriate for the protection of the...

  20. 19 CFR 210.34 - Protective orders; reporting requirement; sanctions and other actions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...; sanctions and other actions. 210.34 Section 210.34 Customs Duties UNITED STATES INTERNATIONAL TRADE...) Issuance of protective order. Upon motion by a party or by the person from whom discovery is sought or by... judge may make any order that may appear necessary and appropriate for the protection of the...

  1. 25 CFR 11.1202 - How to petition for an order of protection.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1202 How to petition for an order of protection. A victim of domestic violence, or the parent, guardian of a victim, or... the act of domestic violence. (b) The petitioner is not required to file for annulment, separation,...

  2. In vivo administration of interleukin-2 protects susceptible mice from Theiler's virus persistence.

    PubMed Central

    Larsson-Sciard, E L; Dethlefs, S; Brahic, M

    1997-01-01

    In vivo administration of interleukin-2 (IL-2)-secreting tumor cells results in complete protection against persistent infection by Theiler's murine encephalomyelitis virus (TMEV) in susceptible DBA/2 mice. The IL-2-mediated protection was found to depend on the inoculum size as well as the timing of IL-2 administration. IL-2-treated and TMEV-infected mice displayed a three- to fourfold relative increase in virus-specific cytotoxic T-lymphocyte (CTL) precursors. Thus, we postulate that the persistence of TMEV infection in susceptible mice reflects limited numbers of relevant CTL precursors and their time course of induction and activation. PMID:8985419

  3. 28 CFR 68.54 - Administrative review of a final order of an Administrative Law Judge in cases arising under...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and served by facsimile or same-day hand delivery, or if such filing or service cannot be made, by... Administrative Hearing Officer shall also be served by facsimile or same-day hand delivery, or if such service... request for administrative review within ten (10) days of the date of entry of the Administrative...

  4. 28 CFR 68.54 - Administrative review of a final order of an Administrative Law Judge in cases arising under...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and served by facsimile or same-day hand delivery, or if such filing or service cannot be made, by... Administrative Hearing Officer shall also be served by facsimile or same-day hand delivery, or if such service... request for administrative review within ten (10) days of the date of entry of the Administrative...

  5. Parenteral administration of attenuated Salmonella Typhimurium ΔznuABC is protective against salmonellosis in piglets.

    PubMed

    Ruggeri, J; Pesciaroli, M; Gaetarelli, B; Scaglione, F E; Pregel, P; Ammendola, S; Battistoni, A; Bollo, E; Alborali, G L; Pasquali, P

    2014-07-01

    A major cause of salmonellosis in humans is the contamination of pork products. Infection in pigs can be controlled using bio-security programs, but they are not sufficient in countries where a high level of infection is recorded. In this context, the use of vaccines can represent a valid supplementary method of control. Recently, we have demonstrated that an attenuated strain of Salmonella enterica serovar Typhimurium (Salmonella Typhimurium ΔznuABC) is protective against systemic and enteric salmonellosis in mouse and pig infection models, candidating this strain as an oral attenuated vaccine. In this study, we compared the efficacy of this attenuated Salmonella Typhimurium strain when administered orally or parenterally. Furthermore, in order to reproduce a pseudo-natural infection model, vaccinated pigs were allocated in the same pen with animals shedding virulent Salmonella Typhimurium. Animals were monitored weekly after vaccination and contact with infected piglets. Diarrhea and ataxia were recorded and Salmonella shedding was tested individually through bacterial culture. After four weeks of cohousing, piglets were euthanized, after which lymph nodes reactivity and gross lesions of the gut sections were scored at necropsy. Organs were submitted to microbiological and histological analyses. The data reported herein show that parenterally vaccinated animals do not shed the attenuated strain, and at the same time the absence of symptoms and decrease in virulent strain shedding in feces from day 6 after challenge demonstrated protection against infection induced by virulent Salmonella Typhimurium. In conclusion, our findings suggest that this is an alternative route of Salmonella Typhimurium ΔznuABC administration, without ignoring the advantages associated with oral vaccination. PMID:24907486

  6. Guarantying the quality of chemotherapy: from the order to the administration.

    PubMed

    Spahni, S; Lovis, C; Ackermann, M; Mach, N; Bonnabry, P; Geissbuhler, A

    2006-01-01

    Ensuring the quality and security when prescribing drugs like chemotherapies is a complex task if one wants to cover the whole chain from the prescribing physician to the administrant nurse. At the University hospitals of Geneva, new applications covering the whole chain from the prescription up to and including the fabrication of the products have been developed in three phases and are being used in a production stage. In order to cover the "last yard" at the bed level, a fourth phase has been started with a pilot study based on labels containing RFID chips for preparations and for patients. The last phase will make use of all traceability data acquired from the prescription to the preparation to validate that the right product is administered to the right patient, and to record who is administrating it. PMID:17108532

  7. 19 CFR 210.34 - Protective orders; reporting requirement; sanctions and other actions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Protective orders; reporting requirement; sanctions and other actions. 210.34 Section 210.34 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Discovery and Compulsory Process § 210.34 Protective...

  8. Intimate Partner Violence, Relationship Status, and Protective Orders: Does "Living in Sin" Entail a Different Experience?

    ERIC Educational Resources Information Center

    Shannon, Lisa; Logan, T. K.; Cole, Jennifer

    2007-01-01

    The legal status of women's intimate relationships may allow for different experiences with intimate partner violence (IPV) and the protections received from the criminal justice system. There has been limited research examining differences in IPV and protective orders for women in marital and cohabiting intimate relationships. This study examines…

  9. Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.

    PubMed

    Lembo, Annalisa; Pelletier, Mark; Iyer, Ravi; Timko, Michele; Dudda, Jan C; West, T Eoin; Wilson, Christopher B; Hajjar, Adeline M; Skerrett, Shawn J

    2008-06-01

    Francisella tularensis is a Gram-negative intracellular pathogen that causes the zoonosis tularemia. Because F. tularensis LPS causes weak TLR4 activation, we hypothesized that administration of a synthetic TLR4 agonist, aminoalkyl glucosaminide phosphate (AGP), would boost the innate immune system and compensate for reduced TLR4 stimulation. Intranasal administration of AGPs induced intrapulmonary production of proinflammatory cytokines and chemokines. Mice treated with AGPs before and after inhalation of Francisella novicida exhibited augmented cytokine and inflammatory responses to infection; reduced bacterial replication in lung, liver, and spleen; and increased survival, whereas all PBS-treated control mice died within 4 days of infection, all AGP-treated mice showed prolonged time-to-death, and 30-60% of AGP-treated mice survived. The protective effect of AGP was lost in mice lacking IFN-gamma. Long-term survivors developed specific Th1 splenocyte responses and specific Abs dominated by IgG2 isotypes. Survivors were fully protected from rechallenge with aerosolized F. novicida. Thus, preventive administration of AGP successfully modulated innate immune responses to aerosolized F. novicida, leading to protective immunity to pneumonic tularemia. This is the first report of the protective effect of a TLR ligand on resistance to F. novicida-induced pneumonic tularemia. PMID:18490759

  10. 25 CFR 11.1204 - Obtaining an emergency order of protection.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1204... petition clearly shows that an act of domestic violence has occurred. The order must meet the content... to have committed a family violence act and seek to hold a hearing as soon as possible. If a...

  11. 25 CFR 11.1204 - Obtaining an emergency order of protection.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1204... petition clearly shows that an act of domestic violence has occurred. The order must meet the content... to have committed a family violence act and seek to hold a hearing as soon as possible. If a...

  12. 25 CFR 11.1204 - Obtaining an emergency order of protection.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1204... petition clearly shows that an act of domestic violence has occurred. The order must meet the content... to have committed a family violence act and seek to hold a hearing as soon as possible. If a...

  13. 25 CFR 11.1204 - Obtaining an emergency order of protection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1204... petition clearly shows that an act of domestic violence has occurred. The order must meet the content... to have committed a family violence act and seek to hold a hearing as soon as possible. If a...

  14. 25 CFR 11.1204 - Obtaining an emergency order of protection.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INDIAN OFFENSES AND LAW AND ORDER CODE Child Protection and Domestic Violence Procedures § 11.1204... petition clearly shows that an act of domestic violence has occurred. The order must meet the content... to have committed a family violence act and seek to hold a hearing as soon as possible. If a...

  15. 78 FR 40773 - Order Imposing Requirements for the Protection of Certain Safeguards Information (Effective...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR... COMMISSION Order Imposing Requirements for the Protection of Certain Safeguards Information (Effective... Information Described Herein I The Licensee, identified in Attachment 1 \\1\\ to this Order, holds a ]...

  16. Social protection in Brazil: universalism and targeting in the FHC and Lula administrations.

    PubMed

    Costa, Nilson do Rosário

    2009-01-01

    This article analyzes the organization of Brazil's social protection system after the Federal Constitution of 1998 (CF 1988). It also demonstrates that 1988 Federal Constitution favored the institutionalization of universalist public policies. This institutionalization took place amidst conflict with the stabilization goals of the Real Plan. The paper argues that such an institutionalization protected public spending in the social area of the macroeconomic management's minimalist project. It also identifies the implementation of social programs targeting the poor during the 1980's decade. Targeting is an innovation directly associated with the adjustment agenda. It reveals that under the FHC and Lula administrations there was an identical adoption of targeted social programs. The targeting of social protection did not possess power of veto over the universalist proposals arising from the democratization in the 1980's. It demonstrates that the Bolsa Família Program (Family Grant Program - PBF), the main mark of the Lula administration, is a large scale adaptation of the targeted programs of direct transfer of income in the FHC administration. The combination of universalism and targeting expanded the scope of social policy. However, the significant growth in social public spending has not been producing broad social results, although the poor in Brazil have benefited from the PBF's targeting. PMID:19547766

  17. Intravenous Administration of Lycopene, a Tomato Extract, Protects against Myocardial Ischemia-Reperfusion Injury

    PubMed Central

    Tong, Chao; Peng, Chuan; Wang, Lianlian; Zhang, Li; Yang, Xiaotao; Xu, Ping; Li, Jinjin; Delplancke, Thibaut; Zhang, Hua; Qi, Hongbo

    2016-01-01

    Background: Oral uptake of lycopene has been shown to be beneficial for preventing myocardial ischemia-reperfusion (I/R) injury. However, the strong first-pass metabolism of lycopene influences its bioavailability and impedes its clinic application. In this study, we determined an intravenous (IV) administration dose of lycopene protects against myocardial infarction (MI) in a mouse model, and investigated the effects of acute lycopene administration on reactive oxygen species (ROS) production and related signaling pathways during myocardial I/R. Methods: In this study, we established both in vitro hypoxia/reoxygenation (H/R) cell model and in vivo regional myocardial I/R mouse model by ligating left anterior artery descending. TTC dual staining was used to assess I/R induced MI in the absence and presence of acute lycopene administration via tail vein injection. Results: Lycopene treatment (1 μM) before reoxygenation significantly reduced cardiomyocyte death induced by H/R. Intravenous administration of lycopene to achieve 1 μM concentration in circulating blood significantly suppressed MI, ROS production, and JNK phosphorylation in the cardiac tissue of mice during in vivo regional I/R. Conclusion: Elevating circulating lycopene to 1 μM via IV injection protects against myocardial I/R injury through inhibition of ROS accumulation and consequent inflammation in mice. PMID:26950150

  18. NonSymmorphic Symmetry Protected Topological Order in Many-body Localized Systems

    NASA Astrophysics Data System (ADS)

    Ashraf, Khalid

    Many-body localized systems have many interesting physical properties such as localization protected quantum order, symmetry protected topological order, area law in entanglement spectrum etc.. Specifically, it has been shown that closed quantum system in 1D i.e. p-wave superconducting wires host localization protected topological order. In this work, we explore the interplay between non-symmorphic symmetry which protects topological order and localization due to disorder. Using a Bogoliubov-de Gennes (BdG) description of p-wave superconductors, we study the topological edge states on a 2D non-symmorphic crystal. We show that a localization protected topological order can exist at high energy in a 2D non-symmorphic crystal. The system goes between topologically trivial and non-trivial phases based on the degree of disorder and shift between the adjacent atoms in the bipartite lattice. We further explore the nature of this phase transition by calculating the entanglement spectrum of the two phases. Finally, the effect of dimensionality on the realization of these phases are discussed.

  19. Predicted impact of mass drug administration on the development of protective immunity against Schistosoma haematobium.

    PubMed

    Mitchell, Kate M; Mutapi, Francisca; Mduluza, Takafira; Midzi, Nicholas; Savill, Nicholas J; Woolhouse, Mark E J

    2014-01-01

    Previous studies suggest that protective immunity against Schistosoma haematobium is primarily stimulated by antigens from dying worms. Praziquantel treatment kills adult worms, boosting antigen exposure and protective antibody levels. Current schistosomiasis control efforts use repeated mass drug administration (MDA) of praziquantel to reduce morbidity, and may also reduce transmission. The long-term impact of MDA upon protective immunity, and subsequent effects on infection dynamics, are not known. A stochastic individual-based model describing levels of S. haematobium worm burden, egg output and protective parasite-specific antibody, which has previously been fitted to cross-sectional and short-term post-treatment egg count and antibody patterns, was used to predict dynamics of measured egg output and antibody during and after a 5-year MDA campaign. Different treatment schedules based on current World Health Organisation recommendations as well as different assumptions about reductions in transmission were investigated. We found that antibody levels were initially boosted by MDA, but declined below pre-intervention levels during or after MDA if protective immunity was short-lived. Following cessation of MDA, our models predicted that measured egg counts could sometimes overshoot pre-intervention levels, even if MDA had had no effect on transmission. With no reduction in transmission, this overshoot occurred if protective immunity was short-lived. This implies that disease burden may temporarily increase following discontinuation of treatment, even in the absence of any reduction in the overall transmission rate. If MDA was additionally assumed to reduce transmission, a larger overshoot was seen across a wide range of parameter combinations, including those with longer-lived protective immunity. MDA may reduce population levels of immunity to urogenital schistosomiasis in the long-term (3-10 years), particularly if transmission is reduced. If MDA is stopped while

  20. Topological and error-correcting properties for symmetry-protected topological order

    NASA Astrophysics Data System (ADS)

    Zeng, Bei; Zhou, D. L.

    2016-03-01

    We study the symmetry-protected topological (SPT) orders for bosonic systems from an information-theoretic viewpoint. We show that with a proper choice of the onsite basis, the degenerate ground-state space of SPT orders (on a manifold with boundary) is a quantum error-correcting code with macroscopic classical distance, hence is stable against any local bit-flip errors. We show that this error-correcting property of the SPT orders has a natural connection to that of the symmetry-breaking orders, whose degenerate ground-state space is a classical error-correcting code with a macroscopic distance, providing a new angle for the hidden symmetry-breaking properties in SPT orders. We further propose new types of topological entanglement entropy that probe the SPT orders hidden in their symmetric ground states, which also signal the topological phase transitions protected by symmetry. Combined with the original definition of topological entanglement entropy that probes the “intrinsic topological orders”, and the recent proposed one that probes the symmetry-breaking orders, the set of different types of topological entanglement entropy may hence distinguish topological orders, SPT orders, and symmetry-breaking orders, which may be mixed up in a single system.

  1. 77 FR 58867 - Public Land Order No. 7799; Withdrawal of Public Land for the Rock Springs Administrative Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... Bureau of Land Management Public Land Order No. 7799; Withdrawal of Public Land for the Rock Springs... the Rock Springs Administrative Site addition. DATES: Effective Date: September 24, 2012. FOR FURTHER... the Rock Springs Administrative Site addition. The land has been and will remain open to...

  2. Master safeguards and security agreements and protection program planning orders and guide

    SciTech Connect

    Hensley, B.

    1988-01-01

    This paper discusses the Master Safeguards and Security Agreement (MSSA) and Protection Program Planning (PPP) orders of the Department of Energy (DOE). Both orders establish DOE policy, requirements, responsibilities, and authorities for the development and implementation of MSSA's and associated planning documents. The MSSA subcommittee to the Policy Development Task Force was responsible for the development of the MSSA order. Unlike other subcommittees that were involved in updating existing orders, the AMSSA subcommittee produced the initial version of the MSSA order. The subcommittee included representation from DOE outlay program offices with Headquarters and field office safeguards and security expertise. The PPP order was developed by a separate subcommittee and included representation mainly from the Task Force itself. It was completed much later than the other orders and remains under review within the Department.

  3. Ethanol Self-Administration in Mice under a Second-Order Schedule

    PubMed Central

    Lamb, Richard J.; Pinkston, Jonathan W.; Ginsburg, Brett C.

    2015-01-01

    Long Fixed-Interval (FI) schedules, particularly second-order schedules, can engender substantial responding before drug or ethanol delivery that is uninfluenced by the direct effects of the drug or ethanol. Thus, these schedules can be used to study the effects of medications upon drug- or ethanol-seeking, uninfluenced by the direct effects of the self-administered drug or ethanol. Long FI second-order schedules are frequently used in primates and occasionally in rats. Under second-order schedules, completion of one response requirement, e.g., a Fixed Ratio 10 (FR10:S), produces a brief stimulus presentation, e.g., a 1-sec 80-dB 4-kHZ tone, and this FR10:S serves as the response unit under another schedule, e.g., a FI 1800-sec. Thus, the first FR10 completed after 1800 sec would result in delivery both of the tone and of reinforcement, e.g., 10 × 0.01 mL 16% (w/v) ethanol. To examine if such schedules could be effectively used in mice, which have advantages in neurobiological and genetic studies, we trained eight C57BL/6J mice to respond under the schedule just described. This schedule maintained substantial responding. The temporal pattern of behavior was typical of an FI schedule with responding accelerating across the interval. We also examined the effects of acute and chronic administration of fluvoxamine on this responding, and these were modest. Finally, we examined responding when alcohol and/or tone deliveries were withheld, and found that extinction occurred most rapidly when both were withheld. This work demonstrates that long FI schedules of ethanol delivery may be useful in studying ethanol seeking in mice. PMID:26254963

  4. Ethanol self-administration in mice under a second-order schedule.

    PubMed

    Lamb, Richard J; Pinkston, Jonathan W; Ginsburg, Brett C

    2015-09-01

    Long Fixed-Interval (FI) schedules, particularly second-order schedules, can engender substantial responding before drug or ethanol delivery that is uninfluenced by the direct effects of the drug or ethanol. Thus, these schedules can be used to study the effects of medications upon drug- or ethanol-seeking, uninfluenced by the direct effects of the self-administered drug or ethanol. Long FI second-order schedules are frequently used in primates and occasionally in rats. Under second-order schedules, completion of one response requirement, e.g., a Fixed Ratio 10 (FR10:S), produces a brief stimulus presentation, e.g., a 1-s 80-dB 4-kHZ tone, and this FR10:S serves as the response unit under another schedule, e.g., an FI 1800-s. Thus, the first FR10 completed after 1800 s would result in delivery both of the tone and of reinforcement, e.g., 10 × 0.01 mL 16% (w/v) ethanol. To examine if such schedules could be effectively used in mice, which have advantages in neurobiological and genetic studies, we trained eight C57BL/6J mice to respond under the schedule just described. This schedule maintained substantial responding. The temporal pattern of behavior was typical of an FI schedule with responding accelerating across the interval. We also examined the effects of acute and chronic administration of fluvoxamine on this responding, and these were modest. Finally, we examined responding when alcohol and/or tone deliveries were withheld, and found that extinction occurred most rapidly when both were withheld. This work demonstrates that long FI schedules of ethanol delivery may be useful in studying ethanol seeking in mice. PMID:26254963

  5. Dexamethasone loaded nanoparticles exert protective effects against Cisplatin-induced hearing loss by systemic administration.

    PubMed

    Sun, Changling; Wang, Xueling; Chen, Dongye; Lin, Xin; Yu, Dehong; Wu, Hao

    2016-04-21

    Ototoxicity is one of the most important adverse effects of cisplatin chemotherapy. As a common treatment of acute sensorineural hearing loss, systemic administration of steroids was demonstrated ineffective against cisplatin-induced hearing loss (CIHL) in published studies. The current study aimed to evaluate the potential protective effect of dexamethasone (DEX) encapsulated in polyethyleneglycol-coated polylactic acid (PEG-PLA) nanoparticles (DEX-NPs) against cisplatin-induced hearing loss following systemic administration. DEX was fabricated into PEG-PLA nanoparticles using emulsion and evaporation technique as previously reported. DEX or DEX-NPs was administered intraperitoneally to guinea pigs 1h before cisplatin administration. Auditory brainstem response (ABR) threshold shifts were measured at four frequencies (4, 8, 16, and 24kHz) 1 day before and three days after cisplatin injection. Cochlear morphology was examined to evaluate inner ear injury induced by cisplatin exposure. A single dose of DEX-NPs 1h before cisplatin treatment resulted in a significant preservation of the functional and structural properties of the cochlea, which was equivalent to the effect of multidose (3 days) DEX injection. In contrast, no significant protective effect was observed by single dose injection of DEX. The results of histological examination of the cochleae were consistent with the functional measurements. In conclusion, a single dose DEX-NPs significantly attenuated cisplatin ototoxicity in guinea pigs after systemic administration at both histological and functional levels indicating the potential therapeutic benefits of these nanoparticles for enhancing the delivery of DEX in acute sensorineural hearing loss. PMID:26971701

  6. 75 FR 26226 - Executive Order 13508 Chesapeake Bay Protection and Restoration Section 203 Final Coordinated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... released for public comment on November 9, 2009 (74 FR 57675, November 9, 2009). This final strategy... Order 13508, Chesapeake Bay Protection and Restoration, dated May 12, 2009 (74 FR 23099, May 15, 2009... May 12, 2009 (74 FR 23099, May 15, 2009), required a Federal Leadership Committee composed of...

  7. 50 CFR 21.48 - Depredation order for double-crested cormorants to protect public resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Depredation order for double-crested cormorants to protect public resources. 21.48 Section 21.48 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION...

  8. 29 CFR 1980.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... violation has occurred may only be made if the complainant has demonstrated that protected behavior or... taken the same unfavorable personnel action in the absence of any protected behavior. Neither...

  9. Systemic Administration of Proteoglycan Protects BALB/c Retired Breeder Mice from Experimental Arthritis

    PubMed Central

    Ishikawa, Larissa Lumi Watanabe; Colavite, Priscila Maria; Fraga-Silva, Thais Fernanda de Campos; Mimura, Luiza Ayumi Nishiyama; França, Thais Graziela Donegá; Zorzella-Pezavento, Sofia Fernanda Gonçalves; Chiuso-Minicucci, Fernanda; Marcolino, Larissa Doddi; Marques, Camila; Ikoma, Maura Rosane Valerio; Sartori, Alexandrina

    2016-01-01

    This study was undertaken to evaluate the prophylactic potential of proteoglycan (PG) administration in experimental arthritis. Female BALB/c retired breeder mice received two (2xPG50 and 2xPG100 groups) or three (3xPG50 group) intraperitoneal doses of bovine PG (50 μg or 100 μg) every three days. A week later the animals were submitted to arthritis induction by immunization with three i.p. doses of bovine PG associated with dimethyldioctadecylammonium bromide adjuvant at intervals of 21 days. Disease severity was daily assessed after the third dose by score evaluation. The 3xPG50 group showed significant reduction in prevalence and clinical scores. This protective effect was associated with lower production of IFN-γ and IL-17 and increased production of IL-5 and IL-10 by spleen cells restimulated in vitro with PG. Even though previous PG administration restrained dendritic cells maturation this procedure did not alter the frequency of regulatory Foxp3+ T cells. Lower TNF-α and IL-6 levels and higher expression of ROR-γ and GATA-3 were detected in the paws of protected animals. A delayed-type hypersensitivity reaction confirmed specific tolerance induction. Taken together, these results indicate that previous PG inoculation determines a specific tolerogenic effect that is able to decrease severity of subsequently induced arthritis. PMID:27294161

  10. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury

    PubMed Central

    Junk, Anna K.; Mammis, Antonios; Savitz, Sean I.; Singh, Manjeet; Roth, Steven; Malhotra, Samit; Rosenbaum, Pearl S.; Cerami, Anthony; Brines, Michael; Rosenbaum, Daniel M.

    2002-01-01

    Erythropoietin (EPO) plays an important role in the brain's response to neuronal injury. Systemic administration of recombinant human EPO (rhEPO) protects neurons from injury after middle cerebral artery occlusion, traumatic brain injury, neuroinflammation, and excitotoxicity. Protection is in part mediated by antiapoptotic mechanisms. We conducted parallel studies of rhEPO in a model of transient global retinal ischemia induced by raising intraocular pressure, which is a clinically relevant model for retinal diseases. We observed abundant expression of EPO receptor (EPO-R) throughout the ischemic retina. Neutralization of endogenous EPO with soluble EPO-R exacerbated ischemic injury, which supports a crucial role for an endogenous EPO/EPO-R system in the survival and recovery of neurons after an ischemic insult. Systemic administration of rhEPO before or immediately after retinal ischemia not only reduced histopathological damage but also promoted functional recovery as assessed by electroretinography. Exogenous EPO also significantly diminished terminal deoxynucleotidyltransferase-mediated dUTP end labeling labeling of neurons in the ischemic retina, implying an antiapoptotic mechanism of action. These results further establish EPO as a neuroprotective agent in acute neuronal ischemic injury. PMID:12130665

  11. 29 CFR 790.17 - “Administrative regulation, order, ruling, approval, or interpretation.”

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... pursuant to statute by an administrative agency, which have the binding effect of law, unless set aside... General's Committee, page 27. To the same effect in 1 Vom Baur, Federal Administrative Law (1942), p....

  12. 29 CFR 790.17 - “Administrative regulation, order, ruling, approval, or interpretation.”

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... pursuant to statute by an administrative agency, which have the binding effect of law, unless set aside... General's Committee, page 27. To the same effect in 1 Vom Baur, Federal Administrative Law (1942), p....

  13. Fifteenth Annual Rank-Order Distribution of Administrative Salaries Paid, 1981-1982.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Administrative salaries in 1981-82 in 132 state-supported universities in 45 states and 31 university systems in 24 states were surveyed. Only full-time administrators were included but their responsibilities and functions range from the director of a single office to the university president. To provide anonymity, the universities are not…

  14. 78 FR 22540 - Department of Energy, Bonneville Power Administration; Notice of Petition for Declaratory Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    ... Energy Regulatory Commission Department of Energy, Bonneville Power Administration; Notice of Petition...(e) and 18 CFR 385.207, the Bonneville Power Administration (Bonneville), submitted certain... the Commission find that Bonneville's tariff, as amended by this filing, substantially conforms or...

  15. The economic costs of partner violence and the cost-benefit of civil protective orders.

    PubMed

    Logan, T K; Walker, Robert; Hoyt, William

    2012-04-01

    Partner violence affects a significant number of women and their children each year. Estimates of the economic costs of partner violence are substantial. However, most estimates of the costs of partner violence are made at the aggregate level rather than the individual level. Estimating costs at the individual level allows for a wider range of costs of partner violence to be considered. This study is one of the first to examine a wide range of economic costs of partner violence and to examine the economic costs and cost-benefits of civil protective orders. Overall, including changes in quality of life, protective orders were estimated to have saved taxpayers in one small state US$85 million in a 1-year period. More generally, this study provides a framework to address more specific complexities associated with cost-benefit analyses of partner violence and the impact of justice system interventions. PMID:22203629

  16. An examination of women's alcohol use and partner victimization experiences among women with protective orders.

    PubMed

    Shannon, Lisa; Logan, Tk; Cole, Jennifer; Walker, Robert

    2008-07-01

    This study examined associations of women's alcohol use with self-reported experiences of male-perpetrated intimate partner violence among a sample of women with protective orders. Participants were 676 women with a protective order against a male intimate partner from three rural areas and one urban area. Multivariate analyses indicated that women's substance use was associated with psychological abuse tactics and severity of physical and sexual victimization in the last year of the relationship. Women's alcohol use was associated with the severity of physical violence within the last year of the relationship, whereas illegal drug use had associations with the number of verbal abuse, degradation and jealousy/control tactics. There was a significant interaction of women's alcohol and drug use with the severity of sexual assault. PMID:18649234

  17. 40 CFR 24.19 - Final order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Final order. 24.19 Section 24.19 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL RULES GOVERNING ISSUANCE OF AND ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS Post-Hearing Procedures § 24.19 Final order. If the Regional Administrator does not...

  18. 40 CFR 24.19 - Final order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Final order. 24.19 Section 24.19 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL RULES GOVERNING ISSUANCE OF AND ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS Post-Hearing Procedures § 24.19 Final order. If the Regional Administrator does not...

  19. 77 FR 76518 - Summary of Commission Practice Relating to Administrative Protective Orders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... the 24-hour rule. See 56 FR 4846 (February 6, 1991); 57 FR 12335 (April 9, 1992); 58 FR 21991 (April 26, 1993); 59 FR 16834 (April 8, 1994); 60 FR 24880 (May 10, 1995); 61 FR 21203 (May 9, 1996); 62 FR 13164 (March 19, 1997); 63 FR 25064 (May 6, 1998); 64 FR 23355 (April 30, 1999); 65 FR 30434 (May...

  20. 78 FR 79481 - Summary of Commission Practice Relating to Administrative Protective Orders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... actions in response to violations of Commission APOs and the 24-hour rule. See 56 FR 4846 (February 6, 1991); 57 FR 12335 (April 9, 1992); 58 FR 21991 (April 26, 1993); 59 FR 16834 (April 8, 1994); 60 FR 24880 (May 10, 1995); 61 FR 21203 (May 9, 1996); 62 FR 13164 (March 19, 1997); 63 FR 25064 (May 6,...

  1. 75 FR 66127 - Summary of Commission Practice Relating to Administrative Protective Orders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... to violations of Commission APOs and the 24-hour rule. See 56 FR 4846 (February 6, 1991); 57 FR 12335 (April 9, 1992); 58 FR 21991 (April 26, 1993); 59 FR 16834 (April 8, 1994); 60 FR 24880 (May 10, 1995); 61 FR 21203 (May 9, 1996); 62 FR 13164 (March 19, 1997); 63 FR 25064 (May 6, 1998); 64 FR...

  2. 76 FR 78945 - Summary of Commission Practice Relating to Administrative Protective Orders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... FR 4846 (February 6, 1991); 57 FR 12335 (April 9, 1992); 58 FR 21991 (April 26, 1993); 59 FR 16834 (April 8, 1994); 60 FR 24880 (May 10, 1995); 61 FR 21203 (May 9, 1996); 62 FR 13164 (March 19, 1997); 63 FR 25064 (May 6, 1998); 64 FR 23355 (April 30, 1999); 65 FR 30434 (May 11, 2000); 66 FR 27685 (May...

  3. 29 CFR 1980.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... administrative law judge, or a named person alleging that the complaint was frivolous or brought in bad faith who... a complaint was frivolous or was brought in bad faith, the Board may award to the named person...

  4. Administration of S-methyl-L-thiocitrulline protects against brain injuries after intracerebral hemorrhage.

    PubMed

    Lu, A; Wagner, K R; Broderick, J P; Clark, J F

    2014-06-13

    Although intracerebral hemorrhage (ICH) increases the level of glutamate in the perihematomal area and cerebral spinal fluid (CSF) in the ICH acute phase, it is unclear whether elevated glutamate activates neuronal nitric oxide synthase (nNOS) in the ICH brain and whether nNOS is an important target for ICH treatment. Here, we assessed the role of the nNOS inhibitor S-methyl-l-thiocitrulline (SMTC) in the activity of NADPH-d and ICH-induced brain injuries. An autologous blood intracerebral infusion model in male rats was used. All of the rats were sacrificed 24h after ICH. ICH increased NADPH-d activity in the striatum. Administering SMTC 3h after ICH decreased the activity of NADH-d (p<0.05 vs. the ICH group). The activation of gelatinolytic enzymes in the perihematomal region of the striatum was reduced by SMTC treatment (p<0.01, vs. the ICH group). The loss of laminin- and occludin-stained vessels was significant in perihematomal regions after 24h of ICH and was significantly attenuated by the administration of SMTC (p<0.01 for laminin, p<0.05 for occluding, compared with the ICH group). Neuronal death and neurological deficits after ICH were also decreased in SMTC treatment rats (p<0.01, vs. the ICH group). The results suggest that the administration of the nNOS inhibitor SMTC after ICH protects against ICH-induced brain injuries and improves neurological function. PMID:24726981

  5. Oral Administration of Fermented Soymilk Products Protects the Skin of Hairless Mice against Ultraviolet Damage

    PubMed Central

    Kano, Mitsuyoshi; Kubota, Norihiro; Masuoka, Norie; Hori, Tetsuji; Miyazaki, Kouji; Ishikawa, Fumiyasu

    2016-01-01

    The protective effect of isoflavones on skin damage from ultraviolet (UV) radiation and their bioavailability were investigated in ovariectomized hairless mice fed diets composed of fermented soymilk containing aglycone forms of isoflavones or control soymilk containing glucose-conjugated forms of isoflavones. The erythema intensity of dorsal skin was significantly higher in ovariectomized mice than in sham-operated mice (p < 0.05). The erythema intensity and epidermal thickness of dorsal skin were significantly lower in the fermented soymilk diet group than in the control diet group (each p < 0.05). Levels of cyclobutane pyrimidine dimers in dorsal skin were significantly lower in the fermented soymilk diet group than in the control group (p < 0.05). Serum and dorsal skin isoflavone concentrations were significantly higher in the fermented soymilk diet group than in the soymilk diet group (p < 0.05). These results indicate that oral administration of a fermented soymilk diet increases isoflavone concentrations in the blood and skin, effectively scavenging the reactive oxygen species generated by UV irradiation and exerting an estrogen-like activity, with a consequent protective effect on skin photodamage in hairless mice. PMID:27556484

  6. Oral Administration of Fermented Soymilk Products Protects the Skin of Hairless Mice against Ultraviolet Damage.

    PubMed

    Kano, Mitsuyoshi; Kubota, Norihiro; Masuoka, Norie; Hori, Tetsuji; Miyazaki, Kouji; Ishikawa, Fumiyasu

    2016-01-01

    The protective effect of isoflavones on skin damage from ultraviolet (UV) radiation and their bioavailability were investigated in ovariectomized hairless mice fed diets composed of fermented soymilk containing aglycone forms of isoflavones or control soymilk containing glucose-conjugated forms of isoflavones. The erythema intensity of dorsal skin was significantly higher in ovariectomized mice than in sham-operated mice (p < 0.05). The erythema intensity and epidermal thickness of dorsal skin were significantly lower in the fermented soymilk diet group than in the control diet group (each p < 0.05). Levels of cyclobutane pyrimidine dimers in dorsal skin were significantly lower in the fermented soymilk diet group than in the control group (p < 0.05). Serum and dorsal skin isoflavone concentrations were significantly higher in the fermented soymilk diet group than in the soymilk diet group (p < 0.05). These results indicate that oral administration of a fermented soymilk diet increases isoflavone concentrations in the blood and skin, effectively scavenging the reactive oxygen species generated by UV irradiation and exerting an estrogen-like activity, with a consequent protective effect on skin photodamage in hairless mice. PMID:27556484

  7. 29 CFR 1978.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Act, the perception of protected activity, was a contributing factor in the adverse action alleged... or the perception thereof. (c) Neither the Assistant Secretary's determination to dismiss a...

  8. 29 CFR 1978.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Act, the perception of protected activity, was a contributing factor in the adverse action alleged... or the perception thereof. (c) Neither the Assistant Secretary's determination to dismiss a...

  9. 29 CFR 1983.109 - Decision and orders of the administrative law judge.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECTION 219 OF THE CONSUMER PRODUCT SAFETY IMPROVEMENT ACT OF 2008. Litigation § 1983.109 Decision and... convincing evidence that it would have taken the same adverse action in the absence of any protected...

  10. 77 FR 31611 - Proposed CERCLA Section 122(g)(4) Administrative Agreement and Order on Consent for the Mercury...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... AGENCY Proposed CERCLA Section 122(g)(4) Administrative Agreement and Order on Consent for the Mercury... the Mercury Refining Superfund Site (``Site'') located in the Towns of Guilderland and Colonie, Albany... Hazardous Substance Superfund Mercury Refining Superfund Site Special Account, which combined total...

  11. 75 FR 53301 - Proposed Cercla Administrative Order on Consent for the Standard Mine Site, Gunnison County, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... Administrative Order on Consent (``AOC'') under sections 104, 106, 107, and 122 of CERCLA, 42 U.S.C. 9604, 9606... County, Colorado. The proposed AOC is for recovery of past and projected future response costs concerning... notice, the Agency will consider all comments received on the AOC and may modify or withdraw its...

  12. 75 FR 51267 - Proposed Cercla Administrative Order On Consent for the Kerber Creek Site, Saguache County, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... Administrative Order on Consent (``AOC'') under sections 104, 106, 107, and 122 of CERCLA, 42 U.S.C. 9604, 9606... the subject of this proposed AOC is all areas to which hazardous substances and/or pollutants or... Bonanza town site, below the Forest Service boundary, and extending to the town of Villa Grove. This...

  13. Order of Administration of Math and Verbal Tests: An Ecological Intervention to Reduce Stereotype Threat on Girls' Math Performance

    ERIC Educational Resources Information Center

    Smeding, Annique; Dumas, Florence; Loose, Florence; Régner, Isabelle

    2013-01-01

    In 2 field experiments, we relied on the very features of real testing situations--where both math and verbal tests are administered--to examine whether order of test administration can, by itself, create vs. alleviate stereotype threat (ST) effects on girls' math performance. We predicted that taking the math test before the verbal test would be…

  14. 78 FR 7994 - Criteria Used To Order Administrative Detention of Food for Human or Animal Consumption

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... July 3, 2011. On May 5, 2011, FDA issued an IFR (76 FR 25538) that implemented section 207 of FSMA and... adulterated or misbranded. '' (Response) As stated in the IFR (76 FR 25538 at 25539), decisions regarding...). (Response) As stated in its response to a comment to the 2004 administrative detention final rule (69...

  15. Twenty-Fourth Annual Rank-Order Distribution of Administrative Salaries Paid, 1990-91.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    This report summarizes the results of the annual survey conducted by the University of Arkansas in 146 state-supported universities representing 49 states and 32 university systems. The survey includes 12-month salaries of full-time administrators paid at major state-supported universities in the United States. The salaries are distributed in rank…

  16. 29 CFR 24.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administrative Review Board. (a) Any party desiring to seek review, including judicial review, of a decision of... Board (“the Board”), U.S. Department of Labor, 200 Constitution Ave., NW., Washington, DC 20210, which... Solicitor, Division of Fair Labor Standards, U.S. Department of Labor, 200 Constitution Ave., NW., N...

  17. 76 FR 25538 - Criteria Used To Order Administrative Detention of Food for Human or Animal Consumption

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... detention of food for human or animal consumption under the Bioterrorism Act (68 FR 25242 at 25250). The... rule) in the Federal Register of May 9, 2003 (68 FR 25242), proposing procedures for the administrative detention of an article of food. In the Federal Register of June 4, 2004 (69 FR 31660), the Agency...

  18. Seventeenth Annual Rank-Order Distribution of Administrative Salaries Paid 1983-1984.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Results of a survey of salaries of full-time administrators at public, doctorate-granting institutions for 1983-1984 are presented. A ranking of salaries paid among 133 universities in 45 states is presented, along with salary data arranged into nine regions defined by the Equal Employment Opportunity Commission. The New York and Boston regions…

  19. Eighteenth Annual Rank-Order Distribution of Administrative Salaries Paid, 1984-85.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Results of a survey of salaries of full-time administrators at public, doctoral-granting institutions for 1984-1985 are presented. A ranking of salaries paid among 151 state-supported universities representing 47 states and 33 university systems representing 27 states is given. Salary data are also arranged into the nine regions defined by the…

  20. Sixteenth Annual Rank-Order Distribution of Administrative Salaries Paid 1982-1983.

    ERIC Educational Resources Information Center

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Salaries of full-time administrators at public, doctoral-granting institutions for 1982-1983 were surveyed. A ranking of salaries paid among 136 universities in 47 states is presented, along with salary data arranged into nine regions defined by the Equal Employment Opportunity Commission. The New York and Boston regions are combined. A table of…

  1. Characteristics related to protection order use among victims of intimate partner violence.

    PubMed

    Durfee, Alesha; Messing, Jill Theresa

    2012-06-01

    One increasingly important resource for victims of intimate partner violence (IPV) is domestic violence civil protection orders (POs). Using a transdisciplinary framework, this article critically examines the use of POs by IPV victims seeking shelter services. Previous contact with police and medical professionals are the strongest predictors of having obtained a PO; education level, income, age, race, and having children in the shelter are also significant predictors of having obtained a PO. These findings are discussed in the context of previous research on help-seeking behaviors and the growing body of transdisciplinary research on violence against women. PMID:22831846

  2. Acute Administration of Natural Honey Protects Isolated Heart in Normothermic Ischemia

    PubMed Central

    Gharekhani, Afshin; Najafi, Moslem; Ghavimi, Hamed

    2012-01-01

    This study intended to assess the efficacy of acute administration of natural honey on cardiac arrhythmias and infarct size when it is used during the normothermic ischemia in isolated rat heart. During 30 min of regional normothermic ischemia followed by 120 min of reperfusion, the isolated hearts were perfused by a modified drug free Krebs-Henseleit solution (control) or the solution containing 0.125, 0.25, 0.5 and 1% of freshly prepared natural honey (test groups), respectively. Cardiac arrhythmias were analyzed and determined through the recorded ECGs. The infarct size was measured using computerized planimetry package. At the ischemic phase, honey (0.25 and 0.5%) decreased the number and duration of ventricular tachycardia (VT), total number of ventricular ectopic beats (VEBs), duration and incidence of reversible ventricular fibrillation (VF) and total VF (p < 0.05 for all). During the reperfusion, concentrations of 0.125, 0.25 and 0.5% lowered the number of VT (p < 0.05), duration of reversible VF (p < 0.01) and total number of VEBs (p < 0.05). In addition, VT duration was reduced significantly with honey 0.125 and 0.25%. Moreover, the infarct size was 45.6 ± 3.4% in the control group, while the perfusion of honey (0.125, 0.25 and 0.5%) reduced it to 14.8 ± 5.1 (p < 0.001), 24.6 ± 7.3 (p < 0.01) and 31.4 ± 7.3% (p < 0.05), respectively. Regarding the results, it is concluded that the acute administration of natural honey in normothermic ischemia conditions can protect the rat heart as the reduction of infarct size and arrhythmias. Conceivably, the antioxidant and free radical scavenging activity, the reduction of necrotized tissue and the providence of rich energy source are more important mechanisms in cardioprotective effects of natural honey. PMID:24250562

  3. Hidden order and flux attachment in symmetry-protected topological phases: A Laughlin-like approach

    NASA Astrophysics Data System (ADS)

    Ringel, Zohar; Simon, Steven H.

    2015-05-01

    Topological phases of matter are distinct from conventional ones by their lack of a local order parameter. Still in the quantum Hall effect, hidden order parameters exist and constitute the basis for the celebrated composite-particle approach. Whether similar hidden orders exist in 2D and 3D symmetry protected topological phases (SPTs) is a largely open question. Here, we introduce a new approach for generating SPT ground states, based on a generalization of the Laughlin wave function. This approach gives a simple and unifying picture of some classes of SPTs in 1D and 2D, and reveals their hidden order and flux attachment structures. For the 1D case, we derive exact relations between the wave functions obtained in this manner and group cohomology wave functions, as well as matrix product state classification. For the 2D Ising SPT, strong analytical and numerical evidence is given to show that the wave function obtained indeed describes the desired SPT. The Ising SPT then appears as a state with quasi-long-range order in composite degrees of freedom consisting of Ising-symmetry charges attached to Ising-symmetry fluxes.

  4. Resource quality of a symmetry-protected topologically ordered phase for quantum computation.

    PubMed

    Miller, Jacob; Miyake, Akimasa

    2015-03-27

    We investigate entanglement naturally present in the 1D topologically ordered phase protected with the on-site symmetry group of an octahedron as a potential resource for teleportation-based quantum computation. We show that, as long as certain characteristic lengths are finite, all its ground states have the capability to implement any unit-fidelity one-qubit gate operation asymptotically as a key computational building block. This feature is intrinsic to the entire phase, in that perfect gate fidelity coincides with perfect string order parameters under a state-insensitive renormalization procedure. Our approach may pave the way toward a novel program to classify quantum many-body systems based on their operational use for quantum information processing. PMID:25860730

  5. Combined administration of taurine and monoisoamyl DMSA protects arsenic induced oxidative injury in rats.

    PubMed

    Flora, Swaran J S; Chouhan, Swapnila; Kannan, Gurusamy M; Mittal, Megha; Swarnkar, Harimohan

    2008-01-01

    of a higher dose of taurine (100 mg/kg) and MiADMSA provided more pronounced effects in improving the antioxidant status of liver and kidney and reducing body arsenic burden compared to the individual treatment of MiADMSA or taurine. The results suggest that in order to achieve better effects of chelation therapy, co-administration of taurine with MiADMSA might be preferred. PMID:19794907

  6. Protective effect of caffeine administration on myocardial ischemia/reperfusion injury in rats.

    PubMed

    Li, Xu-Yong; Xu, Lin; Lin, Guo-Sheng; Li, Xiao-Yan; Jiang, Xue-Jun; Wang, Tao; Lü, Jing-Jun; Zeng, Bin

    2011-09-01

    Many studies have examined the association between coffee consumption and risk of cardiovascular disease, but the results remain controversial. Caffeine is one of the main biologically active compounds of coffee. The aim of this study was to investigate the potential role of caffeine on myocardial ischemia/reperfusion (I/R) injury in the rats. We administered caffeine (25 mg/kg per day) or saline in rats for 4 weeks before myocardial ischemia/reperfusion operation. Compared with the sham group, caffeine treatment decreased ischemia-associated infarct size, serum creatine kinase, and lactate dehydrogenase 3-h reperfusion after 30-min ischemia. Myocardial neutrophil infiltration (assessed by myeloperoxidase activity) was significantly decreased compared with the control group. Meanwhile, caffeine reduced the myocardial apoptosis and suppressed the activation of caspase 3 during myocardial I/R. Importantly, we observed a strong poly(ADP-ribose) polymerase (PARP) activation during myocardial I/R, and caffeine administration inhibited PARP activation and attenuated the expression of PARP-related proinflammatory mediators such as inducible nitric oxide synthetase, IL-6, and TNF-α, all of which may be correlated with downregulated nuclear factor κB activity. We concluded that caffeine protected against myocardial I/R injury by inhibiting inflammation and apoptosis. PMID:21558980

  7. 20 CFR 667.820 - What authority does the Administrative Law Judge have in ordering relief as an outcome of an...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What authority does the Administrative Law Judge have in ordering relief as an outcome of an administrative hearing? 667.820 Section 667.820... What authority does the Administrative Law Judge have in ordering relief as an outcome of...

  8. Short-Range-Order Mineral Physical Protection On Black Carbon Stabilization

    NASA Astrophysics Data System (ADS)

    Liang, B.; Weng, Y. T.; Wang, C. C.; Song, Y. F.; Lehmann, J.; Wang, C. H.

    2015-12-01

    Soil organic matter is one of the largest reservoirs in global carbon cycle, and black carbon (BC) represents a chemical resistant component. Black C plays an important role in global climate change. Generally considered recalcitrant due to high aromaticity, the reactive surface and functional groups of BC are crucial for carbon sequestration in soils. Mineral sorption and physical protection is an important mechanism for BC long term stabilization and sequestration in environments. Previous studies on mineral protection of BC were limited to analysis techniques in two-dimensions, for example, by SEM, TEM, and NanoSIMS. Little is known about the scope of organo-mineral association, the in-situ distribution and forms of minerals, and the ultimate interplay of BC and minerals. The aim of this study is to investigate the three-dimensional interaction of organic C and minerals in submicron scale using synchrotron-based Transmission X-ray Microcopy (TXM) and Fourier-Transform Infrared Spectroscopy (FTIR). Abundant poorly-crystallined nano-minerals particles were observed. These short-range-order (SRO) minerals also aggregate into clusters and sheets, and form envelops-like structures on the surface of BC. On top of large surface contact area, the intimate interplay between BC and minerals reinforces the stability of both organic C and minerals, resulting from chemical bonding through cation bridging and ligand exchange. The mineral protection enhances BC stabilization and sequestration and lowers its bioavailability in environment. The results suggest that mineral physical protection for BC sequestration may be more important than previous understanding.

  9. Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.

    PubMed

    Coates, A S; Tattersall, M H; Swanson, C; Hedley, D; Fox, R M; Raghavan, D

    1984-07-01

    Because of biochemical and tissue culture evidence casting doubt on the physiologic relevance of reported synergy afforded by sequential administration of methotrexate (MTX) followed by 5-fluorouracil (5-FU), a randomized controlled clinical trial was conducted in 108 patients with advanced cancer, including 70 with squamous cell carcinoma (SCC) of the head and neck, nine with SCC of other primary sites, 24 with colorectal, and five with gastric adenocarcinomas. Patients were randomized to receive weekly therapy consisting of MTX followed one hour later by 5-FU, or 5-FU followed one hour later by MTX. There was a trend to higher tumor response rates in patients treated with MTX before 5-FU (45% v 33% overall; 65% v 39% in patients with previously untreated head and neck cancer), but these differences were not significant, either by chi-square test or by multivariate stepwise logistic regression. The trend in survival favoring the reverse sequence of 5-FU before MTX was not significant in univariate analyses. Stepwise multivariate Cox model analysis showed that Eastern Cooperative Oncology Group performance status at study entry was the major prognostic factor for survival (P less than 0.001), but among the 70 patients with head and neck cancer, the sequence of drug administration was the only other significant prognostic factor for survival, and favored the sequence of 5-FU followed by MTX (P less than 0.025). PMID:6376719

  10. 29 CFR 1987.110 - Decision and orders of the Administrative Review Board.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... UNDER SECTION 402 OF THE FDA FOOD SAFETY MODERNIZATION ACT Litigation § 1987.110 Decision and orders of.... 1987.110 Section 1987.110 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... has been delegated the authority to act for the Secretary and issue final decisions under this...

  11. 76 FR 56452 - Proposed Administrative Settlement Agreement and Order on Consent for Removal Action for 6472...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... Agreement and Order on Consent for Removal Action (``AOC'') for a removal action at the 6472 Selkirk Avenue... approval of EPA and the U.S. Department of Justice. The proposed AOC relates to the removal action at the.... 9604(a)(1). EPA is negotiating the proposed AOC pursuant to its authority under Section 122 of...

  12. 40 CFR 24.02 - Issuance of initial orders; definition of final orders and orders on consent.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Issuance of initial orders; definition of final orders and orders on consent. 24.02 Section 24.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL RULES GOVERNING ISSUANCE OF AND ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS General § 24.02...

  13. 40 CFR 24.02 - Issuance of initial orders; definition of final orders and orders on consent.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Issuance of initial orders; definition of final orders and orders on consent. 24.02 Section 24.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL RULES GOVERNING ISSUANCE OF AND ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS General § 24.02...

  14. 40 CFR 24.02 - Issuance of initial orders; definition of final orders and orders on consent.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Issuance of initial orders; definition of final orders and orders on consent. 24.02 Section 24.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL RULES GOVERNING ISSUANCE OF AND ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS General § 24.02...

  15. Hannay Angle: Yet Another Symmetry-Protected Topological Order Parameter in Classical Mechanics

    NASA Astrophysics Data System (ADS)

    Kariyado, Toshikaze; Hatsugai, Yasuhiro

    2016-04-01

    The topological way of thinking now goes beyond quantum solids, and topological characters of classical mechanical systems obeying Newton's law are attracting current interest. To provide a physical insight into the topological numbers in mechanics, we demonstrate the use of the Hannay angle, a "classical" Berry phase, as a symmetry-protected topological order parameter. The Hannay angle is derived using a canonical transformation that maps Newton's equation to a Schrödinger-type equation, and the condition for the quantization is discussed in connection with the symmetry in mechanics. Also, we demonstrate the use of the Hannay angle for a topological characterization of a spring-mass model focusing on the bulk-edge correspondence.

  16. 3 CFR 13637 - Executive Order 13637 of March 8, 2013. Administration of Reformed Export Controls

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Executive Order 13637 of March 8, 2013... Arms Export Control Act, as amended (22 U.S.C. 2751 et seq.) (the “Act”), and section 301 of title 3... under section 3 of the Act (22 U.S.C. 2753), with the exception of subsections (a)(1), (b), (c)(3),...

  17. 6 CFR 29.4 - Protected Critical Infrastructure Information Program administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Ensure the secure sharing of PCII with appropriate authorities and individuals, as set forth in 6 CFR 29... 6 Domestic Security 1 2014-01-01 2014-01-01 false Protected Critical Infrastructure Information... SECRETARY PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.4 Protected Critical Infrastructure...

  18. 6 CFR 29.4 - Protected Critical Infrastructure Information Program administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Ensure the secure sharing of PCII with appropriate authorities and individuals, as set forth in 6 CFR 29... 6 Domestic Security 1 2012-01-01 2012-01-01 false Protected Critical Infrastructure Information... SECRETARY PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.4 Protected Critical Infrastructure...

  19. 6 CFR 29.4 - Protected Critical Infrastructure Information Program administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Ensure the secure sharing of PCII with appropriate authorities and individuals, as set forth in 6 CFR 29... 6 Domestic Security 1 2013-01-01 2013-01-01 false Protected Critical Infrastructure Information... SECRETARY PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.4 Protected Critical Infrastructure...

  20. 6 CFR 29.4 - Protected Critical Infrastructure Information Program administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Ensure the secure sharing of PCII with appropriate authorities and individuals, as set forth in 6 CFR 29... 6 Domestic Security 1 2010-01-01 2010-01-01 false Protected Critical Infrastructure Information... SECRETARY PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.4 Protected Critical Infrastructure...

  1. 6 CFR 29.4 - Protected Critical Infrastructure Information Program administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Ensure the secure sharing of PCII with appropriate authorities and individuals, as set forth in 6 CFR 29... 6 Domestic Security 1 2011-01-01 2011-01-01 false Protected Critical Infrastructure Information... SECRETARY PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.4 Protected Critical Infrastructure...

  2. She said, he said, judge said: analyzing judicial decision making in civil protection order hearings.

    PubMed

    Lucken, Karol; Rosky, Jeffrey W; Watkins, Cory

    2015-07-01

    A modest body of research has examined judicial decision making in civil protection order (CPO) cases. A major finding of this prior research is that the factors expected to shape judicial responses to CPO requests are often found to be insignificant. Because such decisions are often rendered in an environment of vast judicial discretion and competing allegations, the question of "what matters?" assumes added importance. This study examines permanent/final restraining order (PRO) outcomes for intimate partner violence on a number of variables. Specifically, chi-square analyses were performed examining the associations between granting/denying a PRO and demographic, relationship, hearing, and allegation characteristics associated with the petitioner and respondent. These tests helped to reveal relationships at the bivariate level and aided in further model-building using logistic regression and decision-tree analysis. The findings show that the factors most associated with PRO outcomes, namely, the denial of a PRO, are those reflecting the licit rather than illicit behavior of the respondent. PMID:25287407

  3. Administration of kefir-fermented milk protects mice against Giardia intestinalis infection.

    PubMed

    Franco, Mariana Correa; Golowczyc, Marina A; De Antoni, Graciela L; Pérez, Pablo F; Humen, Martín; Serradell, María de los Angeles

    2013-12-01

    Giardiasis, caused by the protozoan Giardia intestinalis, is one of the most common intestinal diseases worldwide and constitutes an important problem for the public health systems of various countries. Kefir is a probiotic drink obtained by fermenting milk with 'kefir grains', which consist mainly of bacteria and yeasts that coexist in a complex symbiotic association. In this work, we studied the ability of kefir to protect mice from G. intestinalis infection, and characterized the host immune response to this probiotic in the context of the intestinal infection. Six- to 8-week-old C75BL/6 mice were separated into four groups: controls, kefir mice (receiving 1 : 100 dilution of kefir in drinking water for 14 days), Giardia mice (infected orally with 4×10(7) trophozoites of G. intestinalis at day 7) and Giardia-kefir mice (kefir-treated G. intestinalis-infected mice), and killed at 2 or 7 days post-infection. Kefir administration was able to significantly reduce the intensity of Giardia infection at 7 days post-infection. An increase in the percentage of CD4(+) T cells at 2 days post-infection was observed in the Peyer's patches (PP) of mice belonging to the Giardia group compared with the control and kefir groups, while the percentage of CD4(+) T cells in PP in the Giardia-kefir group was similar to that of controls. At 2 days post-infection, a reduction in the percentage of B220-positive major histocompatibility complex class II medium cells in PP was observed in infected mice compared with the other groups. At 7 days post-infection, Giardia-infected mice showed a reduction in RcFcε-positive cells compared with the control group, suggesting a downregulation of the inflammatory response. However, the percentages of RcFcε-positive cells did not differ from controls in the kefir and Giardia-kefir groups. An increase in IgA-positive cells was observed in the lamina propria of the kefir group compared with controls at 2 days post-infection. Interestingly, the

  4. Mithramycin protects against dopaminergic neurotoxicity in the mouse brain after administration of methamphetamine.

    PubMed

    Hagiwara, Hiroko; Iyo, Masaomi; Hashimoto, Kenji

    2009-12-01

    The present study was undertaken to examine the effects of mithramycin, an inhibitor of transcription factor Specificity protein (Sp)-1, on the behavioral changes and dopaminergic neurotoxicity in the mouse striatum after administration of methamphetamine (METH). Pretreatment with mithramycin (75, 150 or 300 microg/kg) did not alter acute hyperlocomotion in mice after a single administration of METH (3 mg/kg). However, the development of behavioral sensitization in mice after repeated administration of METH (3 mg/kg/day, once daily for 5 days) was significantly blocked by pretreatment with mithramycin (300 microg/kg). Furthermore, pretreatment with mithramycin (300 microg/kg) significantly attenuated the hyperthermia in mice after repeated administration of METH (3 mg/kgx3, 3-h intervals). Moreover, the combination of pretreatment and subsequent administration of mithramycin (75, 150 or 300 microg/kg) significantly attenuated the reductions of dopamine (DA), its major metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) and DA transporter (DAT) in the striatum after repeated administration of METH (3 mg/kgx3, 3-h intervals), and these attenuations were dose dependent. These findings suggest that mithramycin attenuates the development of behavioral sensitization and dopaminergic neurotoxicity in mice after repeated administration of METH. Therefore, mithramycin could have potential for the treatment of METH abusers, particularly since this drug has been approved by the Food and Drug Administration in the United States. In the future, however, another Sp1 inhibitors with fewer side effects might be more appropriate. PMID:19748494

  5. Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques

    PubMed Central

    Rosenberg, Yvonne J.; Montefiori, David C.; LaBranche, Celia C.; Lewis, Mark G.; Sack, Markus; Lees, Jonathan P.; Jiang, Xiaoming

    2016-01-01

    Intravascular delivery of broadly neutralizing antibodies (bnAbs) has shown promise for prevention and treatment of HIV infection. However, multiple IV administrations in geographic locations with poor accessibility to medical care have practical limitations. We have assessed the efficacy of plant-derived PGT121 delivered subcutaneously (SC) against pre-and post-intravaginal challenge using a rigorous SHIV-SF162P3 macaque protection model. SC administered PGT121 exhibited a longer serum half-life than IV administration and was more consistent than intramuscular delivery. A dose of 3.5mg/kg PGT121 prevented infection at a minimum ID50 neutralization titer of 1:295 while 5mg/kg protected five of six macaques when delivered immediately post-challenge. These results suggest the utility of plant-derived bnAbs delivered SC for HIV prevention. PMID:27031108

  6. Pollution prevention and stratospheric ozone layer protection through innovative procurement methods: The chiller basic ordering agreement

    SciTech Connect

    Snyder, R.E.; Coyle, J.E.; Guice, J.R. Jr.; Kale, S.H.

    1997-12-31

    The Department of Energy (DOE) and the General Services Administration (GSA) have devised an affirmative procurement vehicle to encourage replacement of chillers using chlorofluorocarbon (CFC) refrigerants harmful to the Earth`s stratospheric ozone layer. Procurement selections are based on lowest life cycle cost. Linked with a DOE-developed Equipment Specification for 100 to 2,000 ton chillers that is crafted broadly enough to address about 90% of the Federal water-cooled chiller procurements, the Basic Ordering Agreement (BOA) process significantly reduces redundant design, procurement, and other costs associated with Federal purchasing of chillers through the cutting of red tape associated with buying industrial equipment. While serving to minimize the release of ozone-depleting substances (about six million tons of CFCs) to the environment, the installation of more energy-efficient chillers also promotes environmental stewardship in that reduced energy consumption translates into reduced emissions of noxious gases from the generation of electricity. Use of the BOA to purchase chillers consistent with Federal energy efficiency standards will contribute to reductions of almost a million tons annually of nitrous oxides, sulfur dioxide, and other pollutants from power plant emissions. Reduced electricity consumption of approximately 1.5 billion kilowatt hours per year by switching to more efficient chillers equates to an annual monetary savings of $75 million.

  7. Creating an agricultural world order: regional plant protection problems and international phytopathology, 1878-1939.

    PubMed

    Castonguay, Stéphane

    2010-01-01

    Beginning in 1878 with the International Phylloxera Convention of Berne, international conventions have sought to relieve national agricultural industries from two specific burdens. First, by defining phytosanitary practices to be enforced by national plant protection services, these conventions attempted to prevent the introduction of plant diseases and pests into national territories from which they were previously absent. Second, by standardizing these practices - especially through the design of a unique certificate of inspection - the conventions attempted to eliminate barriers such as quarantines affection international agricultural trade. The succession of phytopathological conventions seemed to epitomize the coalescence of an international community against agricultural pests. What actually coalesced was bio-geopolitics wherein plant pathologists and economic entomologists from North America and the British Empire questioned the so-called internationality of the environmental and economic specificities of continental European agriculture, embodied in "international" conventions. Although an international phenomenon, the dissemination of agricultural pests provided opportunities for cooperation on a strictly regional albeit transnational basis that pitted bio-geopolitical spaces against each other. This article retraces the formation of these spaces by analyzing the deliberations of committees and congresses that gathered to define an international agricultural order based on the means to prevent the spread of plant diseases and pests. PMID:20329355

  8. Issuance of final revised guidance on the use and issuance of administrative orders under Section 7003 of the Resource Conservation and Recovery Act (RCRA). Final report

    SciTech Connect

    Not Available

    1984-09-26

    The directive discusses guidance on the use and issuance of Administrative Orders under Section 7003 of RCRA where there is an emiminent and substantial endangerment to public health and the environment. In order to issue a Section 7003 order, the Administrator must possess evidence that the handling, storage, treatment, transportation or disposal of any solid waste or hazardous waste may present an imminent and substantial endangerment to health or the environment (42 U.S.C. Section 6973). Additionally, Section 7003 requires that the Administrator provide notice to the affected State prior to issuance of the order. Each of these requirements is discussed in the directive.

  9. 40 CFR 22.31 - Final order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Final order. 22.31 Section 22.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CONSOLIDATED RULES OF PRACTICE GOVERNING THE ADMINISTRATIVE ASSESSMENT OF CIVIL PENALTIES AND THE REVOCATION/TERMINATION OR SUSPENSION OF PERMITS Final Order § 22.31 Final order. (a)...

  10. 40 CFR 22.31 - Final order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Final order. 22.31 Section 22.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CONSOLIDATED RULES OF PRACTICE GOVERNING THE ADMINISTRATIVE ASSESSMENT OF CIVIL PENALTIES AND THE REVOCATION/TERMINATION OR SUSPENSION OF PERMITS Final Order § 22.31 Final order. (a)...

  11. Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

    PubMed

    Matta, Benjamin M; Reichenbach, Dawn K; Zhang, Xiaoli; Mathews, Lisa; Koehn, Brent H; Dwyer, Gaelen K; Lott, Jeremy M; Uhl, Franziska M; Pfeifer, Dietmar; Feser, Colby J; Smith, Michelle J; Liu, Quan; Zeiser, Robert; Blazar, Bruce R; Turnquist, Hēth R

    2016-07-21

    During allogeneic hematopoietic cell transplantation (alloHCT), nonhematopoietic cell interleukin-33 (IL-33) is augmented and released by recipient conditioning to promote type 1 alloimmunity and lethal acute graft-versus-host disease (GVHD). Yet, IL-33 is highly pleiotropic and exhibits potent immunoregulatory properties in the absence of coincident proinflammatory stimuli. We tested whether peri-alloHCT IL-33 delivery can protect against development of GVHD by augmenting IL-33-associated regulatory mechanisms. IL-33 administration augmented the frequency of regulatory T cells (Tregs) expressing the IL-33 receptor, suppression of tumorigenicity-2 (ST2), which persist following total body irradiation. ST2 expression is not exclusive to Tregs and IL-33 expands innate immune cells with regulatory or reparative properties. However, selective depletion of recipient Foxp3(+) cells concurrent with peri-alloHCT IL-33 administration accelerated acute GVHD lethality. IL-33-expanded Tregs protected recipients from GVHD by controlling macrophage activation and preventing accumulation of effector T cells in GVHD-target tissue. IL-33 stimulation of ST2 on Tregs activates p38 MAPK, which drives expansion of the ST2(+) Treg subset. Associated mechanistic studies revealed that proliferating Tregs exhibit IL-33-independent upregulation of ST2 and the adoptive transfer of st2(+) but not st2(-) Tregs mediated GVHD protection. In total, these data demonstrate the protective capacity of peri-alloHCT administration of IL-33 and IL-33-responsive Tregs in mouse models of acute GVHD. These findings provide strong support that the immunoregulatory relationship between IL-33 and Tregs can be harnessed therapeutically to prevent GVHD after alloHCT for treatment of malignancy or as a means for tolerance induction in solid organ transplantation. PMID:27222477

  12. Protection against Amorimia septentrionalis poisoning in goats by the continuous administration of sodium monofluoroacetate-degrading bacteria.

    PubMed

    da Silva, Layze C A; Pessoa, Danielle A N; Lopes, Jose R G; de Albuquerque, Laio G; da Silva, Leomyr S A; Garino Junior, Felicio; Riet-Correa, Franklin

    2016-03-01

    The intraruminal inoculation of sodium monofluoroacetate (MFA)-degrading bacteria has been proposed as a method to prevent poisoning by MFA-containing plants. In previous experiments, MFA-degrading bacteria were inoculated intraruminally before or concurrent with plant challenge, with both strategies conferring partial protection to poisoning. To evaluate the protection to Amorimia septentrionalis poisoning provided by the continuous inoculation of MFA-degrading bacteria isolated from plants and soils, 18 goats were divided into three experimental groups of six animals each: Group 1 goats received daily doses of a mixture of Paenibacillus sp. and Cupriavidus sp., and Group 2 goats received a mixture of Ralstonia sp. and Burkholderia sp., for 40 days, while Group 3 goats were not inoculated. Ten days after initiation of bacterial inoculation in Groups 1 and 2, all goats were challenged daily with 5 g/kg body weight of green leaves from A. septentrionalis. Four goats from Group 1 consumed the leaves throughout the 30-day consumption period and showed clinical signs such as transient tachycardia and engorgement of the jugular. The two remaining animals from Group 1 showed obvious signs of intoxication, and plant administration was suspended on days 17 and 19. The goats in Group 2 consumed the leaves throughout the 30-day study without showing signs of poisoning. The goats from Group 3 (control) manifested severe clinical signs of poisoning between the 3rd and 10th days following the start of the A. septentrionalis challenge. Under the conditions of this experiment continuous intraruminal administration of Ralstonia sp. and Burkholderia sp. provided complete protection to poisoning by A. septentrionalis in goats, while continuous intraruminal administration of Paenibacillus sp. and Cupriavidus sp. provided partial protection. PMID:26747472

  13. Protection against D-galactosamine-induced acute liver injury by oral administration of extracts from Lentinus edodes mycelia.

    PubMed

    Watanabe, Aiko; Kobayashi, Masakazu; Hayashi, Shinji; Kodama, Daisuke; Isoda, Katsuhiro; Kondoh, Masuo; Kawase, Masaya; Tamesada, Makoto; Yagi, Kiyohito

    2006-08-01

    The development of oral medications to help prevent liver injury is desirable, and some mushrooms contain chemicals that show promise as such a treatment. Here, we tested whether a hot-water extract (L.E.M.) of the cultured mycelia of an edible mushroom, Lentinus edodes, could protect primary cultured hepatocytes from D-galactosamine (GalN)-induced injury. GalN induced cell death in the hepatocytes, and this effect was completely suppressed by the addition of 0.5 mg/ml L.E.M. Polyphenolic compounds contained in the L.E.M. seemed to be responsible for the protective effect. We next examined the protective effect of L.E.M. in a GalN-induced liver injury model in rats. In rats that had been treated with L.E.M. given orally or intraperitoneally, GalN caused less leakage of aspartate aminotransferase and alanine aminotransferase, markers for liver injury, and a lower decrease in serum protein content, than in non-L.E.M.-treated rats. Histological analysis of the liver also showed a protective effect of L.E.M. Our findings indicate that L.E.M. administration is a promising treatment for protecting the liver from acute injury. PMID:16880621

  14. Managing Vocational Training Systems: A Handbook for Senior Administrators. Quantitative Methods in Social Protection Series.

    ERIC Educational Resources Information Center

    Gasskov, Vladimir

    This book provides state-of-the-art materials relating to the management and organization of public VET (vocational education and training) systems and suggests a framework for developing the management competence of senior administrators. The book is organized by areas of management function and consists of 6 modules with 19 learning units.…

  15. 77 FR 31157 - Providing an Order of Succession Within the Environmental Protection Agency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ..., employees, or agents, or any other person. (Presidential Sig.) THE WHITE HOUSE, May 21, 2012. [FR Doc. 2012... Documents#0;#0; ] Executive Order 13614 of May 21, 2012 Providing an Order of Succession Within the.... 3345 et seq. (the ``Act''), it is hereby ordered that: Section 1. Order of Succession. Subject to...

  16. 97 Savvy Secrets for Protecting Self and School: A Practical Guide for Today's Teachers and Administrators.

    ERIC Educational Resources Information Center

    Sesno, Alice Healy

    A teacher's professional integrity faces numerous challenges in the classroom. To help educators safeguard against potentially career-ending incidents, numerous "survival rules" are provided in this text. It argues that teachers must safeguard themselves with self-protecting knowledge and, in some instances, must reprogram themselves with new…

  17. 28 CFR 541.27 - Protection case-placement in Administrative Detention status.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... detention status as a protection case in the following circumstances. (a) Victim of inmate assault or threats. You were the victim of an inmate assault, or are being threatened by other inmates, including... sexual activity. (b) Inmate informant. Your safety is threatened because you provided, or are...

  18. 3 CFR 13508 - Executive Order 13508 of May 12, 2009. Chesapeake Bay Protection and Restoration

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... laws, and to protect and restore the health, heritage, natural resources, and social and economic value... Historic Trail, the Chesapeake Bay Gateways and Watertrails Network, and the Star-Spangled Banner...

  19. 77 FR 70463 - Public Land Order No. 7801; Withdrawal of Public Lands for Protection of Proposed Expansion of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Public Land Order No. 7801; Withdrawal of Public Lands for Protection of Proposed Expansion of Twentynine Palms, CA Correction In notice document 2012-23479 beginning on page 58864 of the issue of Monday, September 24, 2012 make the...

  20. [The protective activity of 2 normal immunoglobulin preparations for intravenous administration in experimental Pseudomonas aeruginosa infection].

    PubMed

    Vasilev, Ch L; Veleva, K V; Tekelieva, R Kh; Pencheva, P I

    1991-02-01

    The antibody levels in 18 batches of the preparations of human immunoglobulin, Immunovenin and Immunovenin-Intact, for intravenous injection were determined in the enzyme immunoassay with the use of the mixture of P. aeruginosa lipopolysaccharide antigens of seven immunotypes. The average antibody titers in these preparations were identical. The preparations were found to have protective action against P. aeruginosa experimental infection in mice. PMID:1907793

  1. 40 CFR 24.19 - Final order.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Final order. 24.19 Section 24.19... ADMINISTRATIVE HEARINGS ON INTERIM STATUS CORRECTIVE ACTION ORDERS Post-Hearing Procedures § 24.19 Final order. If the Regional Administrator does not adopt portions of the initial order, or finds...

  2. 47 CFR 90.676 - Transition administrator for reconfiguration of the 806-824/851-869 MHz band in order to separate...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Transition administrator for reconfiguration of the 806-824/851-869 MHz band in order to separate cellular systems from non-cellular systems. 90.676... cellular systems from non-cellular systems. The Transition Administrator will be an independent party...

  3. Do family order and neighbor intervention against intimate partner violence protect children from abuse? Findings from Kathmandu.

    PubMed

    Emery, Clifton R; Thapa, Sirjana; Do, Mi Hyang; Chan, Ko Ling

    2015-03-01

    Drawing on previous research on intimate partner violence, child maltreatment, and informal social control, we hypothesized relationships between child abuse severity and (1) protective informal social control of intimate partner violence (ISC_IPV) by neighbors, (2) intimate terrorism, (3) family order, and (4) the power of mothers in intimate relationships. In what we believe may be a first study of physical child abuse by parents in Nepal, we used a three stage cluster approach to draw a random sample of 300 families in Kathmandu. Random effects regression models were used to test the study hypotheses. The analyses found support for hypotheses one and two, but with an important caveat. Although observed (actual) protective ISC_IPV had the hypothesized negative association with child abuse severity, in one of our models perceived protective ISC_IPV was positively associated with child abuse severity. The models clarify that the overall direction of protective ISC_IPV appears to be negative (protective), but the positive finding is important to consider for both research and practice. A significant relationship between family order and child abuse severity was found, but the direction was negative rather than positive as in hypothesis three. Implications for neighborhood research and typological research on IPV and child maltreatment are discussed. PMID:25455214

  4. Administration of defined microbiota is protective in a murine Salmonella infection model

    PubMed Central

    Martz, Sarah-Lynn E.; McDonald, Julie A. K.; Sun, Jun; Zhang, Yong-guo; Gloor, Gregory B.; Noordhof, Curtis; He, Shu-Mei; Gerbaba, Teklu K.; Blennerhassett, Michael; Hurlbut, David J.; Allen-Vercoe, Emma; Claud, Erika C.; Petrof, Elaine O.

    2015-01-01

    Salmonella typhimurium is a major cause of diarrhea and causes significant morbidity and mortality worldwide, and perturbations of the gut microbiota are known to increase susceptibility to enteric infections. The purpose of this study was to investigate whether a Microbial Ecosystem Therapeutic (MET-1) consisting of 33 bacterial strains, isolated from human stool and previously used to cure patients with recurrent Clostridium difficile infection, could also protect against S. typhimurium disease. C57BL/6 mice were pretreated with streptomycin prior to receiving MET-1 or control, then gavaged with S. typhimurium. Weight loss, serum cytokine levels, and S. typhimurium splenic translocation were measured. NF-κB nuclear staining, neutrophil accumulation, and localization of tight junction proteins (claudin-1, ZO-1) were visualized by immunofluorescence. Infected mice receiving MET-1 lost less weight, had reduced serum cytokines, reduced NF-κB nuclear staining, and decreased neutrophil infiltration in the cecum. MET-1 also preserved cecum tight junction protein expression, and reduced S. typhimurium translocation to the spleen. Notably, MET-1 did not decrease CFUs of Salmonella in the intestine. MET-1 may attenuate systemic infection by preserving tight junctions, thereby inhibiting S. typhimurium from gaining access to the systemic circulation. We conclude that MET-1 may be protective against enteric infections besides C. difficile infection. PMID:26531327

  5. 75 FR 14152 - Executive Order 13508; Chesapeake Bay Protection and Restoration Section 502; Guidance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ...-effective tools and practices that reduce water pollution and requests public comment. The document was... Bay Protection and Restoration, dated May 12, 2009 (74 FR 23099, May 15, 2009), requires the... Chesapeake Bay watershed describing proven, cost-effective tools and practices that reduce water...

  6. Delayed protection against ischaemia-induced ventricular arrhythmias and infarct size limitation by the prior administration of Escherichia coli endotoxin.

    PubMed Central

    Song, W.; Furman, B. L.; Parratt, J. R.

    1996-01-01

    1. Bacterial endotoxin (lipopolysaccharide derived from Escherichia coli) was injected intraperitoneally in conscious rats in doses ranging from 0.5 to 2.5 mg kg-1. At various times afterwards the animals were anaesthetized and subjected to a 30 min period of left coronary artery occlusion. 2. Under these conditions the severity of ventricular arrhythmias was markedly suppressed, in comparison with saline-injected controls, but this was particularly marked with the higher doses (1.5 and 2.5 mg kg-1); the number of ventricular premature beats was reduced from 1687 +/- 227 over the 0.5 h coronary artery occlusion period to 190 +/- 46 in those rats administered 2.5 mg kg-1 endotoxin 8 h previously (P < 0.05). The duration of ventricular tachycardia was also significantly reduced (138 +/- 26 s to 8.9 +/- 4.2 s; P < 0.01) and there was a reduction in the incidence of ventricular fibrillation (from 56% to 10%). 3. The time course of this protection was studied following the administration of a single dose of 2.5 mg kg-1 of endotoxin by anaesthetizing rats 4, 8 or 24 h later. Protection was apparent at each time but was particularly marked at 8 h. 4. No rat given the highest dose of endotoxin (32 in all) died as a result of ventricular fibrillation, or from any other cause, during an occlusion, in contrast to a 26% mortality in the controls (P < 0.01). 5. Infarct size, measured following a 30 min period of coronary artery occlusion followed by a 3 h reperfusion period, was reduced both 8 and 24 h after the administration of 2.5 mg kg-1 endotoxin (reductions of 24.3 and 23.1% respectively; P < 0.05). Endotoxin had no significant effect on the area at risk. 6. The beneficial effects of endotoxin on infarct size and on ventricular arrhythmias were markedly attenuated by the prior administration of dexamethasone, 3 mg kg-1 given 1 h prior to endotoxin administration. Dexamethasone itself reduced infarct size (P < 0.05) but had no direct effect on arrhythmia severity following

  7. Prophylactic administration of Amifostine protects vessel thickness in the setting of irradiated bone.

    PubMed

    Page, Erin E; Deshpande, Sagar S; Nelson, Noah S; Felice, Peter A; Donneys, Alexis; Rodriguez, Jose J; Deshpande, Samir S; Buchman, Steven R

    2015-01-01

    Although often beneficial in the treatment of head and neck cancer (HNC), radiation therapy (XRT) leads to the depletion of vascular supply and eventually decreased perfusion of the tissue. Specifically, previous studies have demonstrated the depletion of vessel volume fraction (VVF) and vessel thickness (VT) associated with XRT. Amifostine (AMF) provides protection from the detrimental effects of radiation damage, allowing for reliable post-irradiation fracture healing in the murine mandible. The purpose of this study is to investigate the prophylactic ability of AMF to protect the vascular network in an irradiated field. Sprague-Dawley rats (n = 17) were divided into 3 groups: control (C, n = 5), radiated (XRT, n = 7), and radiated mandibles treated with Amifostine (AMF XRT, n = 5). Both groups receiving radiation underwent a previously established, human equivalent dose of XRT totaling 35 Gy, equally fractionated over 5 days. The AMF XRT group received a weight dependent (0.5 mg AMF/5 g body weight) subcutaneous injection of AMF 45 min prior to XRT. Following a 56-day recovery period, mandibles were perfused, dissected, and imaged with μCT. ANOVA was used for comparisons between groups and p < 0.05 was considered statistically significant. Stereologic analysis demonstrated a significant and quantifiable restoration of VT in AMF treated mandibles as compared to those treated with radiation alone (0.061 ± 0.011 mm versus 0.042 ± 0.004 mm, p = 0.027). Interestingly, further analysis demonstrated no significant difference in VT between control mandibles and those treated with AMF (0.067 ± 0.016 mm versus 0.061 ± 0.011 mm, p = 0.633). AMF treatment also showed an increase in VVF, however those results were not statistically significant from VVF values demonstrated by the XRT group. Our data support the contention that AMF therapy acts prophylactically to protect vessel thickness. Based on these findings, we support the continued

  8. Prophylactic Administration of Amifostine Protects Vessel Thickness in the Setting of Irradiated Bone

    PubMed Central

    Page, Erin E.; Deshpande, Sagar S.; Nelson, Noah S.; Felice, Peter A.; Donneys, Alexis; Rodriguez, Jose J.; Deshpande, Samir S.; Buchman, Steven R.

    2014-01-01

    Although often beneficial in the treatment of head and neck cancer (HNC), radiation therapy (XRT) leads to the depletion of vascular supply and eventually decreased perfusion of the tissue. Specifically, previous studies have demonstrated the depletion of vessel volume fraction (VVF) and vessel thickness (VT) associated with XRT. Amifostine (AMF) provides protection from the detrimental effects of radiation damage, allowing for reliable post-irradiation fracture healing in the murine mandible. The purpose of this study is to investigate the prophylactic ability of AMF to protect the vascular network in an irradiated field. Sprague-Dawley rats (n=17) were divided into 3 groups: control (C, n=5), radiated (XRT, n=7), and radiated mandibles treated with Amifostine (AMF XRT, n=5). Both groups receiving radiation underwent a previously established, human equivalent dose of XRT totaling 35 Gray, equally fractionated over 5 days. The AMF XRT group received a weight dependent (0.5mg AMF/5g body weight) subcutaneous injection of AMF 45 minutes prior to XRT. Following a 56-day recovery period, mandibles were perfused, dissected, and imaged with µCT. ANOVA was used for comparisons between groups and p < 0.05 was considered statistically significant. Stereologic analysis demonstrated a significant and quantifiable restoration of VT in AMF treated mandibles as compared to those treated with radiation alone (0.061±.011mm versus 0.042±0.004mm, p=0.027). Interestingly, further analysis demonstrated no significant difference in VT between control mandibles and those treated with AMF (0.067±0.016mm versus 0.061±0.011mm, p=0.633). AMF treatment also showed an increase in VVF, however those results were not statistically significant from VVF values demonstrated by the XRT group. Our data support the contention that AMF therapy acts prophylactically to protect vessel thickness, as AMF-treated mandibles demonstrate VT levels that are not statistically different from controls in the

  9. Oral administration of a recombinant attenuated Yersinia pseudotuberculosis strain elicits protective immunity against plague.

    PubMed

    Sun, Wei; Sanapala, Shilpa; Rahav, Hannah; Curtiss, Roy

    2015-11-27

    A Yersinia pseudotuberculosis PB1+ (Yptb PB1+) mutant strain combined with chromosome insertion of the caf1R-caf1A-caf1M-caf1 operon and deletions of yopJ and yopK, χ10068 [pYV-ω2 (ΔyopJ315 ΔyopK108) ΔlacZ044::caf1R-caf1M-caf1A-caf1] was constructed. Results indicated that gene insertion and deletion did not affect the growth rate of χ10068 compared to wild-type Yptb cultured at 26 °C. In addition, the F1 antigen in χ10068 was synthesized and secreted on the surface of bacteria at 37 °C (mammalian body temperature), not at ambient culture temperature (26 °C). Immunization with χ10068 primed antibody responses and specific T-cell responses to F1 and YpL (Y. pestis whole cell lysate). Oral immunization with a single dose of χ10068 provided 70% protection against a subcutaneous (s.c.) challenge with ∼ 2.6 × 10(5) LD50 of Y. pestis KIM6+ (pCD1Ap) (KIM6+Ap) and 90% protection against an intranasal (i.n.) challenge with ∼ 500 LD50 of KIM6+Ap in mice. Our results suggest that χ10068 can be used as an effective precursor to make a safe vaccine to prevent plague in humans and to eliminate plague circulation among humans and animals. PMID:26514425

  10. Co-administration of Apelin and T4 Protects Inotropic and Chronotropic Changes Occurring in Hypothyroid Rats

    PubMed Central

    Akhondali, Zahra; Badavi, Mohammad; Dianat, Mahin; Faraji, Farzaneh

    2015-01-01

    Background One of the most important thyroid hormone targets is the cardiovascular system. Hemodynamic changes, such as decreased resting heart rate (HR), myocardial contractility, and cardiac output, and increased diastolic pressure and systemic vascular resistance, have been observed in hypothyroid patients. Moreover, in these patients, ECG changes include sinus bradycardia and low voltage complexes (P waves or QRS complexes). Objective This study aimed at evaluating the prophylactic effect of apelin on HR changes and QRS voltage that occur in propylthiouracil (PTU)-induced hypothyroid rats. Method In this study, 48 adult male Wistar rats weighing 170-235g were randomly divided into 6 groups: Control group (normal saline ip injection + tap water gavage); P group (PTU 0.05%, in drinking water); A group (apelin 200 µg.kg-1.day-1, ip); PA group [co-administration of PTU and apelin]; PT group [co-administration of PTU + T4 (0.2 mg/g per day, gavage)]; and PAT group (co-administration of PTU, apelin and T4). All experiments were performed for 28 consecutive days, and then the animals were anesthetized with an ip injection of ketamine (80 mg/kg) and xylazine (12 mg/kg). Lead II electrocardiogram was recorded to calculate HR and QRS voltage. Results Heart rate and QRS voltage increased more significantly in the hypothyroid group that consumed both apelin and T4 (201 ± 4 beat/min, 0.71 ± 0.02 mv vs. hypothyroid 145 ± 9 beat/min, 0.563 ± 0.015 mv; respectively). Conclusion The co-administration of apelin and T4 showed a protective effect on QRS voltage and HR in PTU‑induced hypothyroid rats. PMID:26247243

  11. Oral administration of patchouli alcohol isolated from Pogostemonis Herba augments protection against influenza viral infection in mice.

    PubMed

    Li, Yu-Cui; Peng, Shao-Zhong; Chen, Hai-Ming; Zhang, Feng-Xue; Xu, Pei-Ping; Xie, Jian-Hui; He, Jing-Jin; Chen, Jian-Nan; Lai, Xiao-Ping; Su, Zi-Ren

    2012-01-01

    Seasonal influenza A infection results in considerable morbidity and mortality. The limited efficacy of available therapeutic strategies stresses the need for development and study of new molecules against influenza virus (IFV). Patchouli alcohol (PA), the major chemical constituent of Pogostemonis Herba, was previously found to strongly inhibit influenza H1N1 replication in vitro. In the present study, the in vivo anti-IFV effect of PA was investigated. In a mouse model infected with lethal levels of FM1, oral administration of PA (20 mg/kg to 80 mg/kg) for 7 d post IFV infection significantly increased the survival rate and survival time. For IFV infection at nonlethal levels, the quantity of IFV in the lungs 5 d after infection was significantly reduced after PA (20 mg/kg to 80 mg/kg) administration. Anti-IFV IgA, IgM, and IgG titers in serum on day 6 were significantly higher in the PA-treated group than the IFV-control group. Anti-IFV immune response augmentation was further confirmed by the elevated production of CD3+, CD4+, and CD8+ T cell levels in blood. Furthermore, the levels of inflammatory cytokines, including TNF-alpha, IL-10 and IFN-gamma in serum of mice, were regulated. Lung inflammation was reduced significantly after PA administration, and the effect may be mediated, at least in part, by regulating the lung levels of inflammatory cytokines. Thus, oral administration of PA appears to be able to augment protection against IFV infection in mice via enhancement of host immune responses, and attenuation of systemic and pulmonary inflammatory responses. PMID:22193241

  12. Betaine protects cerebellum from oxidative stress following levodopa and benserazide administration in rats

    PubMed Central

    Alirezaei, Masoud

    2015-01-01

    Objective(s): The aim of the present study was to evaluate antioxidant and methyl donor effects of betaine in cerebellum following levodopa and benserazide administration in rats. Materials and Methods: Sprague-Dawley male rats were treated with levodopa (LD), betaine (Bet), levodopa plus betaine (LD/Bet), levodopa plus benserazide (LD/Ben), levodopa plus betaine-benserazide (LD/Bet-Ben), and the controls with vehicle for 10 consecutive days, orally. Results: Treatment of rats with LD and benserazide significantly increased total homocysteine in plasma of the LD/Ben group when compared to the other groups. Lipid peroxidation of cerebellum increased significantly in LD-treated rats when compared to the other groups. In contrast, glutathione peroxidase activity and glutathione content in cerebellum were significantly higher in the betaine-treated rats when compared to the LD and LD/Ben groups. Serum dopamine concentration increased significantly in LD-treated rats in comparison with the LD/Ben group. LD/Bet-treated rats also demonstrated significantly higher dopamine levels when compared to the LD/Ben group. Conclusion: We observed valuable effects of Bet in combination with LD and benserazide, which routinely were used for Parkinson’s disease (PD) treatment, in experimentally-induced oxidative stress and hyperhomocysteinemia in rats. Therefore, it seems that Bet is a vital and promising agent regarding PD for future clinical trials in humans. PMID:26730328

  13. Continued Administration of Ciliary Neurotrophic Factor Protects Mice from Inflammatory Pathology in Experimental Autoimmune Encephalomyelitis

    PubMed Central

    Kuhlmann, Tanja; Remington, Leah; Cognet, Isabelle; Bourbonniere, Lyne; Zehntner, Simone; Guilhot, Florence; Herman, Alexandra; Guay-Giroux, Angélique; Antel, Jack P.; Owens, Trevor; Gauchat, Jean-François

    2006-01-01

    Multiple sclerosis is an inflammatory disease of the central nervous system that leads to loss of myelin and oligodendrocytes and damage to axons. We show that daily administration (days 8 to 24) of murine ciliary neurotrophic factor (CNTF), a neurotrophic factor that has been described as a survival and differentiation factor for neurons and oligodendrocytes, significantly ameliorates the clinical course of a mouse model of multiple sclerosis. In the acute phase of experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein peptide 35-55, treatment with CNTF did not change the peripheral immune response but did reduce the number of perivascular infiltrates and T cells and the level of diffuse microglial activation in spinal cord. Blood brain barrier permeability was significantly reduced in CNTF-treated animals. Beneficial effects of CNTF did not persist after it was withdrawn. After cessation of CNTF treatment, inflammation and symptoms returned to control levels. However, slight but significantly higher numbers of oligodendrocytes, NG2-positive cells, axons, and neurons were observed in mice that had been treated with high concentrations of CNTF. Our results show that CNTF inhibits inflammation in the spinal cord, resulting in amelioration of the clinical course of experimental autoimmune encephalomyelitis during time of treatment. PMID:16877358

  14. Oral administration of Lactobacillus plantarum HY7714 protects hairless mouse against ultraviolet B-induced photoaging.

    PubMed

    Kim, Hyun Mee; Lee, Dong Eun; Park, Soo Dong; Kim, Yong-Tae; Kim, Yu Jin; Jeong, Ji Woong; Jang, Sung Sik; Ahn, Young-Tae; Sim, Jae-Hun; Huh, Chul-Sung; Chung, Dae Kyun; Lee, Jung-Hee

    2014-11-28

    Ultraviolet (UV) irradiation alters multiple molecular pathways in the skin, thereby inducing skin damage, including photoaging. In recent years, probiotics have gained interest due to their beneficial effects on skin health, such as inhibiting atopic dermatitis and improving skin immunity or inflammation. However, little is known about the effects of probiotics on UVBinduced photoaging. In this study, we evaluated the effect of Lactobacillus plantarum HY7714 against UVB-induced photoaging in human dermal fibroblasts and hairless mice. The results showed that L. plantarum HY7714 treatment effectively rescued UVB-reduced procollagen expression through the inhibition of UVB-induced matrix metalloproteinase (MMP)-1 expression in human dermal fibroblasts. Data from a western blot showed that L. plantarum HY7714 inhibited the phosphorylation of Jun N-terminal kinase, thereby suppressing the UVB-induced phosphorylation and expression of c-Jun. Oral administration of L. plantarum HY7714 clearly inhibited the number, depth, and area of wrinkles in hairless mouse skin. Histological data showed that L. plantarum HY7714 significantly inhibited UVB-induced epidermal thickness in mice. Western blot and zymography data also revealed that L. plantarum HY7714 effectively inhibited MMP-13 expression as well as MMP-2 and -9 activities in dermal tissue. Collectively, these results provide further insight regarding the skin biological actions of L. plantarum HY7714, a potential skin anti-photoaging agent. PMID:25112318

  15. 40 CFR 86.604-84 - Testing by the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 19 2014-07-01 2014-07-01 false Testing by the Administrator. 86.604... Testing by the Administrator. (a) The Administrator may require by test order that vehicles of a specified...) Whenever the Administrator conducts a test on a test vehicle or the Administrator and manufacturer...

  16. Symmetry protected topological orders and the group cohomology of their symmetry group

    NASA Astrophysics Data System (ADS)

    Chen, Xie; Gu, Zheng-Cheng; Liu, Zheng-Xin; Wen, Xiao-Gang

    2013-04-01

    Symmetry protected topological (SPT) phases are gapped short-range-entangled quantum phases with a symmetry G. They can all be smoothly connected to the same trivial product state if we break the symmetry. The Haldane phase of spin-1 chain is the first example of SPT phases which is protected by SO(3) spin rotation symmetry. The topological insulator is another example of SPT phases which are protected by U(1) and time-reversal symmetries. In this paper, we show that interacting bosonic SPT phases can be systematically described by group cohomology theory: Distinct d-dimensional bosonic SPT phases with on-site symmetry G (which may contain antiunitary time-reversal symmetry) can be labeled by the elements in H1+d[G,UT(1)], the Borel (1+d)-group-cohomology classes of G over the G module UT(1). Our theory, which leads to explicit ground-state wave functions and commuting projector Hamiltonians, is based on a new type of topological term that generalizes the topological θ term in continuous nonlinear σ models to lattice nonlinear σ models. The boundary excitations of the nontrivial SPT phases are described by lattice nonlinear σ models with a nonlocal Lagrangian term that generalizes the Wess-Zumino-Witten term for continuous nonlinear σ models. As a result, the symmetry G must be realized as a non-on-site symmetry for the low-energy boundary excitations, and those boundary states must be gapless or degenerate. As an application of our result, we can use H1+d[U(1)⋊Z2T,UT(1)] to obtain interacting bosonic topological insulators (protected by time reversal Z2T and boson number conservation), which contain one nontrivial phase in one-dimensional (1D) or 2D and three in 3D. We also obtain interacting bosonic topological superconductors (protected by time-reversal symmetry only), in term of H1+d[Z2T,UT(1)], which contain one nontrivial phase in odd spatial dimensions and none for even dimensions. Our result is much more general than the above two examples, since it

  17. Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats

    PubMed Central

    Sayd, Aline; Antón, María; Alén, Francisco; Caso, Javier Rubén; Pavón, Javier; Leza, Juan Carlos; Rodríguez de Fonseca, Fernando

    2015-01-01

    Background: The acylethanolamides oleoylethanolamide and palmitoylethanolamide are endogenous lipid mediators with proposed neuroprotectant properties in central nervous system (CNS) pathologies. The precise mechanisms remain partly unknown, but growing evidence suggests an antiinflammatory/antioxidant profile. Methods: We tested whether oleoylethanolamide/palmitoylethanolamide (10mg/kg, i.p.) attenuate neuroinflammation and acute phase responses (hypothalamus-pituitary-adrenal (HPA) stress axis stress axis activation, thermoregulation, and anhedonia) induced by lipopolysaccharide (0.5mg/kg, i.p.) in rats. Results: Lipopolysaccharide increased mRNA levels of the proinflammatory cytokines tumor necrosis factor-α, interleukin-1β, and interleukin-6, nuclear transcription factor-κB activity, and the expression of its inhibitory protein IκBα in cytoplasm, the inducible isoforms of nitric oxide synthase and cyclooxygenase-2, microsomal prostaglandin E2 synthase mRNA, and proinflammatory prostaglandin E2 content in frontal cortex 150 minutes after administration. As a result, the markers of nitrosative/oxidative stress nitrites (NO2 -) and malondialdehyde were increased. Pretreatment with oleoylethanolamide/ palmitoylethanolamide reduced plasma tumor necrosis factor-α levels after lipopolysaccharide, but only oleoylethanolamide significantly reduced brain tumor necrosis factor-α mRNA. Oleoylethanolamide and palmitoylethanolamide prevented lipopolysaccharide-induced nuclear transcription factor-κB (NF-κB)/IκBα upregulation in nuclear and cytosolic extracts, respectively, the expression of inducible isoforms of nitric oxide synthase, cyclooxygenase-2, and microsomal prostaglandin E2 synthase and the levels of prostaglandin E2. Additionally, both acylethanolamides reduced lipopolysaccharide-induced oxidative/nitrosative stress. Neither oleoylethanolamide nor palmitoylethanolamide modified plasma corticosterone levels after lipopolysaccharide, but both

  18. Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1

    PubMed Central

    Wan, Shu-Wen; Lu, Yi-Tien; Huang, Chia-Hui; Lin, Chiou-Feng; Anderson, Robert; Liu, Hsiao-Sheng; Yeh, Trai-Ming; Yen, Yu-Ting; Wu-Hsieh, Betty A.; Lin, Yee-Shin

    2014-01-01

    Background Infection with dengue virus (DENV) may cause life-threatening disease with thrombocytopenia and vascular leakage which are related to dysfunction of platelets and endothelial cells. We previously showed that antibodies (Abs) against DENV nonstructural protein 1 (NS1) cross-react with human platelets and endothelial cells, leading to functional disturbances. Based on sequence homology analysis, the C-terminal region of DENV NS1 protein contains cross-reactive epitopes. For safety in vaccine development, the cross-reactive epitopes of DENV NS1 protein should be deleted or modified. Methodology/Principal Findings We tested the protective effects of Abs against full-length DENV NS1, NS1 lacking the C-terminal amino acids (a.a.) 271-352 (designated ΔC NS1), and chimeric DJ NS1 consisting of N-terminal DENV NS1 (a.a. 1-270) and C-terminal Japanese encephalitis virus NS1 (a.a. 271-352). The anti-ΔC NS1 and anti-DJ NS1 Abs showed a lower binding activity to endothelial cells and platelets than that of anti-DENV NS1 Abs. Passive immunization with anti-ΔC NS1 and anti-DJ NS1 Abs reduced DENV-induced prolonged mouse tail bleeding time. Treatment with anti-DENV NS1, anti-ΔC NS1 and anti-DJ NS1 Abs reduced local skin hemorrhage, controlled the viral load of DENV infection in vivo, synergized with complement to inhibit viral replication in vitro, as well as abolished DENV-induced macrophage infiltration to the site of skin inoculation. Moreover, active immunization with modified NS1 protein, but not with unmodified DENV NS1 protein, reduced DENV-induced prolonged bleeding time, local skin hemorrhage, and viral load. Conclusions/Significance These results support the idea that modified NS1 proteins may represent an improved strategy for safe and effective vaccine development against DENV infection. PMID:24658118

  19. Ischemic Postconditioning and Nitric Oxide Administration Failed to Confer Protective Effects in a Porcine Model of Extracorporeal Cardiopulmonary Resuscitation.

    PubMed

    Psotova, Hana; Ostadal, Petr; Mlcek, Mikulas; Kruger, Andreas; Janotka, Marek; Vondrakova, Dagmar; Svoboda, Tomas; Hrachovina, Matej; Taborsky, Ludek; Dudkova, Vlasta; Strunina, Svitlana; Kittnar, Otomar; Neuzil, Petr

    2016-04-01

    The protective effects of ischemic postconditioning (IPC) and nitric oxide (NO) administration have been demonstrated in several ischemic scenarios. However, current evidence regarding the effect of IPC and NO in extracorporeal cardiopulmonary resuscitation remains lacking. Fifteen female swine (body weight 45 kg) underwent veno-arterial extracorporeal membrane oxygenation (ECMO) implantation; cardiac arrest-ventricular fibrillation was induced by rapid ventricular pacing. After 20 min of cardiac arrest, blood flow was restored by increasing the ECMO flow rate to 4.5 L/min. The animals (five per group) were then randomly assigned to receive IPC (three cycles of 3 min ischemia and reperfusion), NO (80 ppm via oxygenator), or mild hypothermia (HT; 33.0°C). Cerebral oximetry and aortic blood pressure were monitored continuously. After 90 min of reperfusion, blood samples were drawn for the measurement of troponin I, myoglobin, creatine-phosphokinase, alanine aminotransferase, neuron-specific enolase, cystatin C, and reactive oxygen metabolite (ROM) levels. Significantly higher blood pressure and cerebral oxygen saturation values were observed in the HT group compared with the IPC and NO groups (P < 0.05). The levels of troponin I, myoglobin, creatine phosphokinase, and alanine aminotransferase were significantly lower in the HT group (P < 0.05); levels of neuron-specific enolase, cystatin C, and ROM were not significantly different. IPC and NO were comparable in all monitored parameters. The results of the present study indicate that IPC and NO administration are not superior interventions to HT for the maintenance of blood pressure, cerebral oxygenation, organ protection, and suppression of oxidative stress following extracorporeal cardiopulmonary resuscitation. PMID:26412075

  20. 75 FR 47475 - Acetamiprid, Mepiquat; Order Denying NRDC’s Objections on Remand: Environmental Protection Agency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    .... (70 FR 46706 (August 10, 2005)). NRDC sought judicial review of the August, 2005 order, and the U.S..., total bilirubin, albumin, hormones, and enzymes such as alkaline phosphatase, alanine aminotransfersase... Exposure to Pesticides in Food (June 21, 2000). (See 73 FR 42683, 42687 (July 23, 2008)). ii. Exposure...

  1. 50 CFR 21.48 - Depredation order for double-crested cormorants to protect public resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... asphyxiation. Persons using shotguns must use nontoxic shot, as listed in 50 CFR 20.21(j). Persons using egg... WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE... order is to reduce the occurrence and/or minimize the risk of adverse impacts to public resources...

  2. Ethanol and Phencyclidine Interact with Respect to Nucleus Accumbens Dopamine Release: Differential Effects of Administration Order and Pretreatment Protocol

    PubMed Central

    Pickering, Chris; Chau, Pei Pei; Söderpalm, Bo; Ericson, Mia

    2010-01-01

    Executive dysfunction is a common symptom among alcohol-dependent individuals. Phencyclidine (PCP) injection induces dysfunction in the prefrontal cortex of animals but little is known about how PCP affects the response to ethanol. Using the in vivo microdialysis technique in male Wistar rats, we investigated how systemic injection of 5 mg/kg PCP would affect the dopamine release induced by local infusion of 300 mM ethanol into the nucleus accumbens. PCP given 60 min before ethanol entirely blocked ethanol-induced dopamine release. However, when ethanol was administered 60 min before PCP, both drugs induced dopamine release and PCP's effect was potentiated by ethanol (180% increase vs 150%). To test the role of prefrontal cortex dysfunction in ethanol reinforcement, animals were pretreated for 5 days with 2.58 mg/kg PCP according to previously used ‘PFC hypofunction protocols’. This, however, did not change the relative response to PCP or ethanol compared to saline-treated controls. qPCR illustrated that this low PCP dose did not significantly change expression of glucose transporters Glut1 (SLC2A1) or Glut3 (SLC2A3), monocarboxylate transporter MCT2 (SLC16A7), glutamate transporters GLT-1 (SLC1A2) or GLAST (SLC1A3), the immediate early gene Arc (Arg3.1) or GABAergic neuron markers GAT-1 (SLC6A1) and parvalbumin. Therefore, we concluded that PCP at a dose of 2.58 mg/kg for 5 days did not induce hypofunction in Wistar rats. However, PCP and ethanol do have overlapping mechanisms of action and these drugs differentially affect mesolimbic dopaminergic transmission depending on the order of administration. PMID:20589092

  3. 75 FR 44163 - Antidumping and Countervailing Duty Proceedings: Electronic Filing Procedures; Administrative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE... Proceedings: Electronic Filing Procedures; Administrative Protective Order Procedures AGENCY: Import Administration, International Trade Administration, Department of Commerce. ACTION: Proposed Rule; Request...

  4. 40 CFR 173.8 - Final order.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Final order. 173.8 Section 173.8... order. (a) If the State does not request a hearing within the sixty-day time period and the Administrator has not issued an order withdrawing the notice of intent to rescind, the Administrator shall...

  5. A computer simulation study of optimal thyroid radiation protection during investigations involving the administration of radioiodine-labelled pharmaceuticals.

    PubMed

    Wootton, R; Hammond, B J

    1978-04-01

    The administration of iodide for thyroid blocking is now known to carry its own risks, at least in certain categories of patients. We have therefore made a theoretical study by computer simulation of the efficacy of various thyroid blocking regimes. In the case of injected 125I- or 131I-iodide, substantial thyroid protection may theoretically be achieved by a single oral dose of inorganic iodide, for example a 90% reduction in radiation dose is produced by only 20 mg iodide. Repeating the initial blocking dose is of little value. A single blocking dose, however, affords poor protection against radioiodine released from labelled plasma proteins. Both for short-lived proteins such as fibrinogen, and for the longer-lived proteins such as albumin, the optimum dosage schedule appears to be stable iodide given daily for two to three weeks. For instance, 10 mg daily for a fortnight will reduce thyroid irradiation by a factor of ten following injection of 125I-fibrinogen. PMID:647182

  6. 40 CFR 305.35 - Proposed findings, conclusions, and order.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... order. 305.35 Section 305.35 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS COMPREHENSIVE ENVIRONMENTAL RESPONSE, COMPENSATION, AND LIABILITY ACT (CERCLA) ADMINISTRATIVE HEARING PROCEDURES FOR CLAIMS AGAINST THE...

  7. Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment.

    PubMed

    Wang, Peiqi; Cao, Jiangbei; Liu, Na; Ma, Li; Zhou, Xueyue; Zhang, Hong; Wang, Yongan

    2016-01-01

    Postoperative cognitive dysfunction (POCD) is a clinical syndrome characterized by cognitive declines in patients after surgery. Previous studies have suggested that surgery contributed to such impairment. It has been proven that neuroinflammation may exacerbate surgery-induced cognitive impairment in aged rats. The free radical scavenger edaravone has high blood brain barrier permeability, and was demonstrated to effectively remove free radicals from the brain and alleviate the development of POCD in patients undergoing carotid endarterectomy, suggesting its potential role in preventing POCD. For this reason, this study was designed to determine whether edaravone is protective against POCD through its inhibitory effects on inflammatory cytokines and oxidative stress. First, Sprague Dawley adult male rats were administered 3 mg/kg edaravone intraperitoneally after undergoing a unilateral nephrectomy combined with lipopolysaccharide injection. Second, behavioral parameters related to cognitive function were recorded by fear conditioning and Morris Water Maze tests. Last, superoxide dismutase activities and malondialdehyde levels were measured in the hippocampi and prefrontal cortex on postoperative days 3 and 7, and microglial (Iba1) activation, p-Akt and p-mTOR protein expression, and synaptic function (synapsin 1) were also examined 3 and 7 days after surgery. Rats that underwent surgery plus lipopolysaccharide administration showed significant impairments in spatial and working memory, accompanied by significant reductions in hippocampal-dependent and independent fear responses. All impairments were attenuated by treatment with edaravone. Moreover, an abnormal decrease in superoxide dismutase activation, abnormal increase in malondialdehyde levels, significant increase in microglial reactivity, downregulation of p-Akt and p-mTOR protein expression, and a statistically significant decrease in synapsin-1 were observed in the hippocampi and prefrontal cortices of

  8. [Protective effect of combined administration of active ingredients of Danhong on cerebral micro-vascular endothelial cell injured by hypoxia].

    PubMed

    Zhou, Hui-fen; He, Yu; Zhang, Yu-yan; Yang, Jie-hong; Zhao, Tao; Fu, Wei; Zhou, Peng; Wan, Hai-tong

    2014-11-01

    To study the protective effect of combined administration of active ingredients of Danhong on cultured primary mice's brain microvascular endothelial cells (rBMECs) injured by hypoxia. Primary mice's brain micro-vascular endothelial cells were cultured to establish the 4 h hypoxia model. Meanwhile, active ingredients (protocatechuic aldehyde, salvianolic acid B, hydroxysafflor yellow A and tanshinol) of Danhong were administered in rBMECs. The non-toxic dosage was determined by MTT. The leakage of lactate dehydrogenase(LDH), cell superoxide dismutase (SOD) activity and MDA level were detected by the colorimetric method. The expressions of ICAM-1, MMP-9, P53 mRNA were detected by RT-PCR method. Changes in rBMECs cell cycle and early apoptosis were detected by flow cytometry. Danhong's active ingredients and prescriptions 1, 2, 3, 7, 8, 9 could be combined to significantly restrain LDH in hypoxic cells supernatant. Prescriptions 1, 2, 3, 7, 8, 9 could significantly enhance SOD activity in anoxic cells; Prescriptions 1, 2, 3, 8, 9 could significantly decrease the MDA level; Prescriptions 1, 2, 6, 7, 9 could significantly inhibit the early rB-MECs apoptosis induced by hypoxia. After hypoxia, the up-regulated P53 mRNA expression could cause retardation in G, phase and promote cell apoptosis. This proved that the regulatory function of P53 gene lay in monitoring of calibration points in G, phase. Prescriptions 1, 2, 5, 6, 7, 8, 9 could significantly down-regulate the P53 mRNA expression; Prescriptions 1, 4, 7, 8, 9 could significantly down-regulate the ICAM-1 mRNA expression; Prescriptions 1, 3, 6, 9 could significantly down-regulate the MMP-9 mRNA expression. The combined administration of Danhong's active ingredients showed a significant protective effect on primary cultured rBMECs injury induced by hypoxia Its mechanism may be related to the enhancement of cellular antioxidant capacity and the inhibition of inflammatory response and cell apoptosis. This study could

  9. Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment

    PubMed Central

    Liu, Na; Ma, Li; Zhou, Xueyue; Zhang, Hong; Wang, Yongan

    2016-01-01

    Postoperative cognitive dysfunction (POCD) is a clinical syndrome characterized by cognitive declines in patients after surgery. Previous studies have suggested that surgery contributed to such impairment. It has been proven that neuroinflammation may exacerbate surgery-induced cognitive impairment in aged rats. The free radical scavenger edaravone has high blood brain barrier permeability, and was demonstrated to effectively remove free radicals from the brain and alleviate the development of POCD in patients undergoing carotid endarterectomy, suggesting its potential role in preventing POCD. For this reason, this study was designed to determine whether edaravone is protective against POCD through its inhibitory effects on inflammatory cytokines and oxidative stress. First, Sprague Dawley adult male rats were administered 3 mg/kg edaravone intraperitoneally after undergoing a unilateral nephrectomy combined with lipopolysaccharide injection. Second, behavioral parameters related to cognitive function were recorded by fear conditioning and Morris Water Maze tests. Last, superoxide dismutase activities and malondialdehyde levels were measured in the hippocampi and prefrontal cortex on postoperative days 3 and 7, and microglial (Iba1) activation, p-Akt and p-mTOR protein expression, and synaptic function (synapsin 1) were also examined 3 and 7 days after surgery. Rats that underwent surgery plus lipopolysaccharide administration showed significant impairments in spatial and working memory, accompanied by significant reductions in hippocampal-dependent and independent fear responses. All impairments were attenuated by treatment with edaravone. Moreover, an abnormal decrease in superoxide dismutase activation, abnormal increase in malondialdehyde levels, significant increase in microglial reactivity, downregulation of p-Akt and p-mTOR protein expression, and a statistically significant decrease in synapsin-1 were observed in the hippocampi and prefrontal cortices of

  10. Intranasal administration of aTf protects and repairs the neonatal white matter after a cerebral hypoxic-ischemic event.

    PubMed

    Guardia Clausi, Mariano; Paez, Pablo M; Campagnoni, Anthony T; Pasquini, Laura A; Pasquini, Juana M

    2012-10-01

    Our previous studies showed that the intracerebral injection of apotransferrin (aTf) attenuates white matter damage and accelerates the remyelination process in a neonatal rat model of cerebral hypoxia-ischemia (HI) injury. However, the intracerebral injection of aTf might not be practical for clinical treatments. Therefore, the development of less invasive techniques capable of delivering aTf to the central nervous system would clearly aid in its effective clinical use. In this work, we have determined whether intranasal (iN) administration of human aTf provides neuroprotection to the neonatal mouse brain following a cerebral hypoxic-ischemic event. Apotransferrin was infused into the naris of neonatal mice and the HI insult was induced by right common carotid artery ligation followed by exposure to low oxygen concentration. Our results showed that aTf was successfully delivered into the neonatal HI brain and detected in the olfactory bulb, forebrain and posterior brain 30 min after inhalation. This treatment successfully reduced white matter damage, neuronal loss and astrogliosis in different brain regions and enhanced the proliferation and survival of oligodendroglial progenitor cells (OPCs) in the subventricular zone and corpus callosum (CC). Additionally, using an in vitro hypoxic model, we demonstrated that aTf prevents oligodendrocyte progenitor cell death by promoting their differentiation. In summary, these data suggest that iN administration of aTf has the potential to be used for clinical treatment to protect myelin and to induce remyelination in demyelinating hypoxic-ischemic events in the neonatal brain. PMID:22736466

  11. Co-administration of interleukins 7 and 15 with DNA vaccine improves protective immunity against Toxoplasma gondii.

    PubMed

    Chen, Jia; Li, Zhong-Yuan; Petersen, Eskild; Liu, Wen-Ge; Zhu, Xing-Quan

    2016-03-01

    Toxoplasma gondii is an obligatory intracellular parasite, which can infect all warm-blooded animals including humans. Cytokines, including IL-15 and IL-7, play a critical role in the regulation of the homeostasis of naive and memory T cells. Co-administration the DNA vaccine with cytokines may improve its efficacy. IL-7 and IL-15 from splenic tissues of Kunming mice were cloned, and eukaryotic plasmid pVAX-IL-7-IL-15 was constructed. Kunming mice were administrated with DNA vaccine expressing T. gondii calcium-dependent protein kinase 1 (TgCDPK1), pVAX-CDPK1, in the presence or absence of IL-7 and IL-15 plasmids (pVAX-IL-7-IL-15), immune responses were analyzed including lymphoproliferative assay, cytokine and serum antibody measurements, flow cytometric surface markers on lymphocytes, and thus protective immunity against acute and chronic T. gondii infection was estimated. Mice injected with pVAX-CDPK1 supplemented with pVAX-IL-7-IL-15 showed higher Toxoplasma-specific IgG2a titers, Th1 responses associated with the production of IFN-γ, IL-2 as well as cell-mediated cytotoxic activity where stronger frequencies of IFN-γ secreting CD8+ and CD4+ T cells (CD8+/CD4+ IFN-γ+ T cells) compared to controls. Co-administration of pVAX-IL-7-IL-15 and pVAX-CDPK1 significantly (P < 0.05) increased survival time (18.07 ± 5.43 days) compared with pVAX-CDPK1 (14.13 ± 3.85 days) or pVAX-IL-7-IL-15 (11.73 ± 1.83 days) alone, and pVAX-IL-7-IL-15 + pVAX-CDPK1 significantly reduced the number of brain cysts (73.5%) in contrast to pVAX-CDPK1 (46.0%) or pVAX-IL-7-IL-15 alone (45.0%). Our results indicate that supplementation of DNA vaccine with IL-7 and IL-15 would facilitate specific humoral and cellular immune responses elicited by DNA vaccine against acute and chronic T. gondii infection in mice. PMID:26706605

  12. Detection of symmetry-protected topological order in AKLT states by exact evaluation of the strange correlator

    NASA Astrophysics Data System (ADS)

    Wierschem, K.; Beach, K. S. D.

    2016-06-01

    The strange correlator [Phys. Rev. Lett. 112, 247202 (2014), 10.1103/PhysRevLett.112.247202] has been proposed as a measure of symmetry protected topological order in one- and two-dimensional systems. It takes the form of a spin-spin correlation function, computed as a mixed overlap between the state of interest and a trivial local product state. We demonstrate that it can be computed exactly (asymptotically, in the Monte Carlo sense) for various Affleck-Kennedy-Lieb-Tasaki states by direct evaluation of the wave function within the valence bond loop gas framework. We present results for lattices with chain, square, honeycomb, cube, diamond, and hyperhoneycomb geometries. In each case, the spin quantum number S is varied such that 2 S (the number of valence bonds emerging from each site) achieves various integer multiples of the lattice coordination number. We introduce the concept of strange correlator loop winding number and point to its utility in testing for the presence of symmetry protected topological order.

  13. Protective effect of hesperidin on oxidative and histological liver damage following carbon tetrachloride administration in Wistar rats

    PubMed Central

    Çiftçi, Osman; Otlu, Ali

    2016-01-01

    Introduction In the current study, the protective effect of hesperidin (HP) on carbon tetrachloride (CCl4)-induced hepatotoxicity in rats was investigated. Material and methods Twenty-eight rats were divided equally into four groups. The first group was kept as a control and given only vehicle. In the second, rats were orally administered 50 mg/kg/day HP for 10 days. Carbon tetrachloride was given in a single intraperitoneal injection at the dose of 2 ml/kg in the third group. In the fourth group, the rats were treated with equal doses of CCl4 and HP. Results It was found that CCl4 induced oxidative stress via a significant increase in the formation of thiobarbituric acid-reactive substances (TBARS) and caused a significant decline in the levels of glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) in rats. In contrast, HP blocked these toxic effects induced by CCl4, causing an increase in GSH, CAT and SOD levels and decreased formation of TBARS (p < 0.01). In addition, histopathological damage increased with CCl4 treatment. In contrast, HP treatment eliminated the effects of CCl4 and stimulated anti-apoptotic events, as characterized by reduced caspase-3 activation. Conclusions The current study demonstrated that CCl4-induced hepatotoxicity can be prevented with HP treatment. Thus, co-administration of HP with CCl4 may be useful for attenuating the negative effects of CCl4 on the liver. PMID:27279838

  14. Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania.

    PubMed

    Valvassori, Samira S; Arent, Camila O; Steckert, Amanda V; Varela, Roger B; Jornada, Luciano K; Tonin, Paula T; Budni, Josiane; Mariot, Edemilson; Kapczinski, Flávio; Quevedo, João

    2015-08-01

    Several studies have suggested that alterations in brain-derived neurotrophic factor (BDNF) and increased oxidative stress have a central role in bipolar disorder (BD). Intracerebroventricular (ICV) injection of ouabain (OUA) in rats alters oxidative stress parameters and decreases BDNF levels in the brain. In this context, the present study aims to investigate the effects of BDNF ICV administration on BDNF levels and oxidative stress parameters in brains of rats submitted to animal model of mania induced by OUA. Wistar rats received an ICV injection of OUA, artificial cerebrospinal fluid (ACSF), OUA plus BDNF, or ACSF plus BDNF. Locomotor activity and risk-taking behavior in the rats were measured using the open-field test. In addition, we analyzed the BDNF levels and oxidative stress parameters (TBARS, Carbonyl, CAT, SOD, GR, and GPx) in the frontal cortex and hippocampus of rats. The BDNF was unable to reverse the ouabain-induced hyperactivity and risk-taking behavior. Nevertheless, BDNF treatment increased BDNF levels, modulated the antioxidant enzymes, and protected the OUA-induced oxidative damage in the brain of rats. These results suggest that BDNF alteration observed in BD patients may be associated with oxidative damage, both seen in this disorder. PMID:25164569

  15. Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman.

    PubMed

    Gordon, Richard K; Haigh, Julian R; Garcia, Gregory E; Feaster, Shawn R; Riel, Michael A; Lenz, David E; Aisen, Paul S; Doctor, Bhupendra P

    2005-12-15

    maximal inhibition of AChE (26.2%) and concentration of PB (17.1 ng/mL) occurred at 2.5 h post-PB dosing. AChE activity returned to almost 100% of pre-dose values by 6 h. A dose-dependent linear correlation was found between the amount of PB measured in the blood and the inhibition of AChE. Following soman (GD) exposure, recovered AChE activity was similar to levels that were reversibly protected by the PB administration. Therefore, the WRAIR ChE WB data clearly supports the conclusion that PB is an effective pre-treatment drug for nerve agent exposure (GD). In the second FDA human study for the treatment of Alzheimer's disease, the WRAIR ChE WB assay was used to determine the RBC-AChE and serum BChE profile of healthy elderly volunteers receiving Huperzine A. Huperzine A is a plant-derived reversible and selective AChE inhibitor compared to BChE, and is a more potent inhibitor of AChE than PB. Huperzine A is available as a nutraceutical, a natural supplement reported to improve memory, and has a variety of neuroprotective effects. Individuals received an increasing dose regimen of huperzine A (final dose 200 microg after 4 weeks), which produced more than 50% inhibition of RBC-AChE. Huperzine A was well tolerated by these patients at doses that sequestered more RBC-AChE than PB, and thus warrants further study as a prophylaxis for OP poisoning in addition to Alzheimer's therapy. Due to the documented use of OPs by terrorists and in warfare around the globe, Federal, State, and local authorities need a reliable, fast, inexpensive, and standard method for confirming such an assault in order to initiate appropriate containment, decontamination, and treatment measures. This assay is ideal for prescreening military personnel for atypical ChE activities that would preclude their deployment to areas of potential CWA exposure. The WRAIR WB ChE assay will fulfill the requirement for rapid and reliable monitoring of such exposure in military and civilian populations. PMID:16256090

  16. 19 CFR 351.213 - Administrative review of orders and suspension agreements under section 751(a)(1) of the Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agreements under section 751(a)(1) of the Act. 351.213 Section 351.213 Customs Duties INTERNATIONAL TRADE... during the anniversary month of the publication of an antidumping or countervailing duty order, a...) of the Act of specified individual exporters or producers covered by an order (except for...

  17. 19 CFR 351.213 - Administrative review of orders and suspension agreements under section 751(a)(1) of the Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agreements under section 751(a)(1) of the Act. 351.213 Section 351.213 Customs Duties INTERNATIONAL TRADE... during the anniversary month of the publication of an antidumping or countervailing duty order, a...) of the Act of specified individual exporters or producers covered by an order (except for...

  18. 19 CFR 351.213 - Administrative review of orders and suspension agreements under section 751(a)(1) of the Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agreements under section 751(a)(1) of the Act. 351.213 Section 351.213 Customs Duties INTERNATIONAL TRADE... during the anniversary month of the publication of an antidumping or countervailing duty order, a...) of the Act of specified individual exporters or producers covered by an order (except for...

  19. 19 CFR 351.213 - Administrative review of orders and suspension agreements under section 751(a)(1) of the Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agreements under section 751(a)(1) of the Act. 351.213 Section 351.213 Customs Duties INTERNATIONAL TRADE... during the anniversary month of the publication of an antidumping or countervailing duty order, a...) of the Act of specified individual exporters or producers covered by an order (except for...

  20. 19 CFR 351.213 - Administrative review of orders and suspension agreements under section 751(a)(1) of the Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agreements under section 751(a)(1) of the Act. 351.213 Section 351.213 Customs Duties INTERNATIONAL TRADE... during the anniversary month of the publication of an antidumping or countervailing duty order, a...) of the Act of specified individual exporters or producers covered by an order (except for...

  1. 40 CFR 205.159 - Testing by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Testing by the Administrator. 205.159... Administrator. (a)(1) In order for the Administrator to determine whether such vehicles or a manufacturer's test facility conform to applicable regulations, the Administrator may require that vehicles to be...

  2. 40 CFR 90.504 - Testing by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Testing by the Administrator. 90.504... Enforcement Auditing § 90.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 90.507 and submitted to the Administrator at the place designated for the purpose...

  3. 40 CFR 205.170 - Testing by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Testing by the Administrator. 205.170... the Administrator. (a)(1) In order for the Administrator to determine whether such exhaust systems or a manufacturer's test facility conform to applicable regulations, the Administrator may require...

  4. 40 CFR 89.504 - Testing by the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Testing by the Administrator. 89.504... Enforcement Auditing § 89.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 89.507 and submitted to the Administrator at the place designated for the purpose...

  5. 40 CFR 90.504 - Testing by the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Testing by the Administrator. 90.504... Enforcement Auditing § 90.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 90.507 and submitted to the Administrator at the place designated for the purpose...

  6. 40 CFR 91.605 - Testing by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Testing by the Administrator. 91.605... Regulations § 91.605 Testing by the Administrator. (a) The Administrator may require by test order under § 91... § 91.606 and submitted to the Administrator at the place designated for the purpose of...

  7. 40 CFR 91.605 - Testing by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Testing by the Administrator. 91.605... Regulations § 91.605 Testing by the Administrator. (a) The Administrator may require by test order under § 91... § 91.606 and submitted to the Administrator at the place designated for the purpose of...

  8. 40 CFR 205.170 - Testing by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Testing by the Administrator. 205.170... the Administrator. (a)(1) In order for the Administrator to determine whether such exhaust systems or a manufacturer's test facility conform to applicable regulations, the Administrator may require...

  9. 40 CFR 205.159 - Testing by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Testing by the Administrator. 205.159... Administrator. (a)(1) In order for the Administrator to determine whether such vehicles or a manufacturer's test facility conform to applicable regulations, the Administrator may require that vehicles to be...

  10. 40 CFR 89.504 - Testing by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Testing by the Administrator. 89.504... Enforcement Auditing § 89.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 89.507 and submitted to the Administrator at the place designated for the purpose...

  11. 40 CFR 86.604-84 - Testing by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Testing by the Administrator. 86.604....604-84 Testing by the Administrator. (a) The Administrator may require by test order that vehicles of... conformity was issued. (b)(1) Whenever the Administrator conducts a test on a test vehicle or...

  12. 40 CFR 89.504 - Testing by the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Testing by the Administrator. 89.504... Enforcement Auditing § 89.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 89.507 and submitted to the Administrator at the place designated for the purpose...

  13. 40 CFR 86.604-84 - Testing by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Testing by the Administrator. 86.604....604-84 Testing by the Administrator. (a) The Administrator may require by test order that vehicles of... conformity was issued. (b)(1) Whenever the Administrator conducts a test on a test vehicle or...

  14. 40 CFR 86.604-84 - Testing by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 20 2013-07-01 2013-07-01 false Testing by the Administrator. 86.604....604-84 Testing by the Administrator. (a) The Administrator may require by test order that vehicles of... conformity was issued. (b)(1) Whenever the Administrator conducts a test on a test vehicle or...

  15. 40 CFR 205.170 - Testing by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Testing by the Administrator. 205.170... the Administrator. (a)(1) In order for the Administrator to determine whether such exhaust systems or a manufacturer's test facility conform to applicable regulations, the Administrator may require...

  16. 40 CFR 91.605 - Testing by the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Testing by the Administrator. 91.605... Regulations § 91.605 Testing by the Administrator. (a) The Administrator may require by test order under § 91... § 91.606 and submitted to the Administrator at the place designated for the purpose of...

  17. 40 CFR 90.504 - Testing by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Testing by the Administrator. 90.504... Enforcement Auditing § 90.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 90.507 and submitted to the Administrator at the place designated for the purpose...

  18. 40 CFR 205.159 - Testing by the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Testing by the Administrator. 205.159... Administrator. (a)(1) In order for the Administrator to determine whether such vehicles or a manufacturer's test facility conform to applicable regulations, the Administrator may require that vehicles to be...

  19. 40 CFR 205.170 - Testing by the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Testing by the Administrator. 205.170... the Administrator. (a)(1) In order for the Administrator to determine whether such exhaust systems or a manufacturer's test facility conform to applicable regulations, the Administrator may require...

  20. 40 CFR 90.504 - Testing by the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Testing by the Administrator. 90.504... Enforcement Auditing § 90.504 Testing by the Administrator. (a) The Administrator may require by test order... requirements of § 90.507 and submitted to the Administrator at the place designated for the purpose...