Science.gov

Sample records for adopted international standards

  1. Determinants of Effective Information Transfer in International Regulatory Standards Adoption

    ERIC Educational Resources Information Center

    Popescu, Denisa

    2010-01-01

    The role of international regulatory standards within the current global environment has become of the most importance. The age of the global system and free market capitalism carried us into the unprecedented age of regulations, and standard setting. Regulations are now becoming the emerging mode of global governance. This study focuses on…

  2. Travelers' Health: International Adoption

    MedlinePlus

    ... preadoption living standards, varying disease epidemiology in the countries of origin, the presence of previously unidentified medical problems, and ... know the disease risks in the adopted child’s country of origin and the medical and social histories of the ...

  3. India Needs International Standards in Accreditation Problems in Adoption and Implementation

    ERIC Educational Resources Information Center

    Naik, B. M.

    2012-01-01

    The paper outlines in brief, need and importance of introducing global quality standards in accreditation, prescribed by the international agreement "Washington Accord". This agreement is initially provisional and after scrutiny, if found fit, it is upgraded to Signatory status. It is this status which empowers students of engineering,…

  4. Why Adoption of Standards Matters

    ERIC Educational Resources Information Center

    Journal of Staff Development, 2016

    2016-01-01

    A total of 39 states have adopted, adapted, or endorsed the Standards for Professional Learning, including the standards issued in 2011 (labeled in red) and those published earlier (labeled in blue). Making a commitment to the standards is a commitment to continuous learning for all educators in a school.

  5. Special topics in international adoption.

    PubMed

    Jenista, Jerri Ann

    2005-10-01

    As international adoption has become more "mainstream," the issues recently addressed in domestic adoption have become more important in adoptions involving children originating in other countries. Certain groups of prospective adoptive parents, such as gay or lesbian couples, single parents, and parents with disabilities, have begun to apply to adopt in ever increasing numbers. Children who may have been considered unadoptable in the past are now routinely being offered to prospective adoptive parents. The numbers and ages of the children placed and the spacing between adoptions have come under scrutiny. The rates of adoption dissolutions and disruptions are being examined carefully by the receiving and sending countries. There is a pressing need for research into numerous social aspects of adoption.

  6. Enabling international adoption of LOINC through translation

    PubMed Central

    Vreeman, Daniel J.; Chiaravalloti, Maria Teresa; Hook, John; McDonald, Clement J.

    2012-01-01

    Interoperable health information exchange depends on adoption of terminology standards, but international use of such standards can be challenging because of language differences between local concept names and the standard terminology. To address this important barrier, we describe the evolution of an efficient process for constructing translations of LOINC terms names, the foreign language functions in RELMA, and the current state of translations in LOINC. We also present the development of the Italian translation to illustrate how translation is enabling adoption in international contexts. We built a tool that finds the unique list of LOINC Parts that make up a given set of LOINC terms. This list enables translation of smaller pieces like the core component “hepatitis c virus” separately from all the suffixes that could appear with it, such “Ab.IgG”, “DNA”, and “RNA”. We built another tool that generates a translation of a full LOINC name from all of these atomic pieces. As of version 2.36 (June 2011), LOINC terms have been translated into 9 languages from 15 linguistic variants other than its native English. The five largest linguistic variants have all used the Part-based translation mechanism. However, even with efficient tools and processes, translation of standard terminology is a complex undertaking. Two of the prominent linguistic challenges that translators have faced include: the approach to handling acronyms and abbreviations, and the differences in linguistic syntax (e.g. word order) between languages. LOINC’s open and customizable approach has enabled many different groups to create translations that met their needs and matched their resources. Distributing the standard and its many language translations at no cost worldwide accelerates LOINC adoption globally, and is an important enabler of interoperable health information exchange PMID:22285984

  7. States Adopt Standards at Fast Clip

    ERIC Educational Resources Information Center

    Gewertz, Catherine

    2010-01-01

    Nearly half the states have adopted a new set of common academic standards, barely a month after their final release and, in most cases, with little opposition. As of July 9, 23 states had decided to replace their mathematics and English/language arts standards with the common set. Another flurry of adoptions is expected by Aug. 2, since the $4…

  8. A Narrative Inquiry of International Adoption Stories

    ERIC Educational Resources Information Center

    Pryor, Christin; Pettinelli, J. Douglas

    2011-01-01

    The international adoption entrance story is an unexplored topic in the adoption literature. The stories that families tell of beginning life with their new children has important implications for the development of an autobiographical narrative of an adopted child. A coherent autobiographical narrative is vital for healthy childhood development.…

  9. International Adoption: Current Status and Future Prospects.

    ERIC Educational Resources Information Center

    Bartholet, Elizabeth

    1993-01-01

    Laws regulating adoption are varied and complex in countries that offer children for international adoption (IA), while United States Immigration laws pose additional obstacles to Americans wishing to adopt foreign-born children. Declarations by the United Nations and the development of a convention on IA by the Hague Conference offer some hope…

  10. Update on international adoption: focus on Russia.

    PubMed

    McGuinness, Teena M; Robinson, Cheryl Broadus

    2011-06-01

    American families will continue to adopt children from foreign countries; the desire to have a child transcends national boundaries. Sadly, not all adoptions have happy outcomes. A recent and well-reported incident involved an American mother, who, exasperated with her adopted son's severe behavioral problems, returned him to Russia, alone, on an aircraft. Other tragic reports involve internationally adopted children who have died at the hands of their American parents. This article provides an overview of the consequences of institutionalization as a risk factor for behavioral health of children; implications for nursing care of adoptive families follow. PMID:21598869

  11. The African Orphan Crisis and International Adoption

    ERIC Educational Resources Information Center

    Roby, Jini L.; Shaw, Stacey A.

    2006-01-01

    The plight of Africa's AIDS orphans has reached crisis proportions, and the international community is beginning to mobilize at the family, community, national, and international levels. Despite these encouraging efforts, the response is inadequate, and increased attention and action are needed. The authors suggest that international adoption,…

  12. [Choosing the name in international adoption].

    PubMed

    van Effenterre, Aude; Harf, Aurélie; Skandrani, Sandra; Taïeb, Olivier; Moro, Marie Rose

    2014-01-01

    In the context of international adoption, the question is raised of the links which the adoptive parents may or may not maintain with the culture of the child's birth country. The name which the adoptive parents choose reflects this questioning. A study was carried out into this subject with parents and children in order to gain a better understanding of the feelings of belonging, filiation and affiliation in these situations.

  13. Internationally Adopted Children: Important Information for Parents

    MedlinePlus

    ... iodine). Newborn metabolic screen up to 2 years. Infectious Diseases PPD or currently recommended testing for tuberculosis exposure ( ... Pediatrics. Medical Evaluation of Internationally Adopted Children for Infectious Diseases. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS, ...

  14. The African orphan crisis and international adoption.

    PubMed

    Roby, Jini L; Shaw, Stacey A

    2006-07-01

    The plight of Africa's AIDS orphans has reached crisis proportions, and the international community is beginning to mobilize at the family, community, national, and international levels. Despite these encouraging efforts, the response is inadequate, and increased attention and action are needed. The authors suggest that international adoption, although a small and temporary solution, may fit within the framework being used as a global working model. Issues surrounding adoption, such as racism, racial and cultural identity development, waiting children in the U.S. public child welfare system, and the potential legal risks, are delineated. The African perspective toward adoption is presented, although the response varies and is not collectively defined. The authors conclude that although international adoptions should be used as a last-resort solution, and with tight regulations, the potential benefits to some children merit the opening of a dialogue on the topic.

  15. Predicting Language Outcomes for Internationally Adopted Children

    ERIC Educational Resources Information Center

    Glennen, Sharon L.

    2007-01-01

    Purpose: Language and speech are difficult to assess in newly arrived internationally adopted children. The purpose of this study was to determine if assessments completed when toddlers were first adopted could predict language outcomes at age 2. Local norms were used to develop early intervention guidelines that were evaluated against age 2…

  16. [International adoption: children's health risk evolution].

    PubMed

    Dartiguenave, C

    2012-05-01

    The socioeconomic and sanitary conditions in many countries make it necessary to weigh as precisely as possible the uncertainties which might affect the health of internationally adopted children, which is one of the key drivers to adoption decision. Indeed, health troubles are more and more frequent among children proposed by countries, at a time when there are fewer children to be adopted. Hence the institutions and the actors in the field of international adoption are compelled to frequently update their professional practices, so as to cope both with the declining offer for adoptable children and with the increasing pressure from the birth countries of children to make host countries adopt children with high age or with special needs. It also requires from the administrations the will to provide better initial information and to implement the demand for an agreement. Meanwhile, in spite of those growing constraints, adopting families have been more and more risk adverse during the latest decades, this being a common trend in our developed countries.

  17. International Adoption: Benefits, Risks, and Vulnerabilities

    ERIC Educational Resources Information Center

    Rochat, Tamsen; Richter, Linda

    2007-01-01

    International adoption is on the rise in the United States and is not without controversy. Reasons for the increase include higher rates of infertility in couples who have delayed parenthood; increased numbers of children who are relinquished, abandoned, or orphaned around the world; and the influence of third party agencies. Internationally…

  18. Information architecture: Profile of adopted standards

    SciTech Connect

    1997-09-01

    The Department of Energy (DOE), like other Federal agencies, is under increasing pressure to use information technology to improve efficiency in mission accomplishment as well as delivery of services to the public. Because users and systems have become interdependent, DOE has enterprise wide needs for common application architectures, communication networks, databases, security, and management capabilities. Users need open systems that provide interoperability of products and portability of people, data, and applications that are distributed throughout heterogeneous computing environments. The level of interoperability necessary requires the adoption of DOE wide standards, protocols, and best practices. The Department has developed an information architecture and a related standards adoption and retirement process to assist users in developing strategies and plans for acquiring information technology products and services based upon open systems standards that support application software interoperability, portability, and scalability. This set of Departmental Information Architecture standards represents guidance for achieving higher degrees of interoperability within the greater DOE community, business partners, and stakeholders. While these standards are not mandatory, particular and due consideration of their applications in contractual matters and use in technology implementations Department wide are goals of the Chief Information Officer.

  19. Skin diseases in internationally adopted children.

    PubMed

    Rigal, Émilie; Nourrisson, Céline; Sciauvaud, Julie; Pascal, Julie; Texier, Charlotte; Corbin, Violaine; Poirier, Véronique; Beytout, Jean; Labbe, André; Lesens, Olivier

    2016-08-01

    Internationally adopted children often present diseases contracted in the country of origin. Skin diseases are common in new arrivals, and diagnosis may prove challenging for GPs or even dermatologists if they are inexperienced in the extensive geographic and ethnic diversity of international adoptees. To analyse the frequency and characteristics of skin diseases in international adoptees. In total, 142 adoptees were evaluated for a cross-sectional cohort study. The most frequent diseases observed at arrival were dermatological conditions. Of the adoptees, 70% presented at least one skin disease, of which 57.5% were infectious; Tinea capitis being the most frequent (n = 42). The recovery rate of Tinea capitis was 89% (n = 32/36). Ten cases of scabies were diagnosed. Other diseases included viral skin infection (n = 22), with 16 cases of Molluscum contagiosum and bacterial infection. Skin diseases are very common in internationally adopted children. There is a need for close collaboration between dermatologists and paediatricians to diagnose such infections, as well as clear guidelines to treat them. PMID:27436771

  20. Adopting Internet Standards for Orbital Use

    NASA Technical Reports Server (NTRS)

    Wood, Lloyd; Ivancic, William; da Silva Curiel, Alex; Jackson, Chris; Stewart, Dave; Shell, Dave; Hodgson, Dave

    2005-01-01

    After a year of testing and demonstrating a Cisco mobile access router intended for terrestrial use onboard the low-Earth-orbiting UK-DMC satellite as part of a larger merged ground/space IP-based internetwork, we reflect on and discuss the benefits and drawbacks of integration and standards reuse for small satellite missions. Benefits include ease of operation and the ability to leverage existing systems and infrastructure designed for general use, as well as reuse of existing, known, and well-understood security and operational models. Drawbacks include cases where integration work was needed to bridge the gaps in assumptions between different systems, and where performance considerations outweighed the benefits of reuse of pre-existing file transfer protocols. We find similarities with the terrestrial IP networks whose technologies we have adopted and also some significant differences in operational models and assumptions that must be considered.

  1. Occupational Standards: International Perspectives.

    ERIC Educational Resources Information Center

    Oliveira, Joao, Ed.

    These nine papers from a conference of the International Research Network for Training and Development focus on occupational classification, standards, and certification. "Introduction" (Joao Oliveria) presents synopses with highlights from the papers. Part I offers an overview of recent developments in the United States in "Occupational Standards…

  2. Sensory Processing in Internationally Adopted, Post-Institutionalized Children

    ERIC Educational Resources Information Center

    Wilbarger, Julia; Gunnar, Megan; Schneider, Mary; Pollak, Seth

    2010-01-01

    Background/Methods: Sensory processing capacities of 8-12-year-old internationally adopted (IA) children who experienced prolonged institutional care (greater than 12 months with 75% of pre-adoption lives in institutional care) prior to adoption into family environments (PI) were compared to a group of IA children who were adopted early (less than…

  3. Health Data Standards and Adoption Process: Preliminary Findings of a Qualitative Study in Saudi Arabia

    ERIC Educational Resources Information Center

    Alkraiji, Abdullah; Jackson, Thomas; Murray, Ian

    2011-01-01

    Purpose: This paper seeks to carry out a critical study of health data standards and adoption process with a focus on Saudi Arabia. Design/methodology/approach: Many developed nations have initiated programs to develop, promote, adopt and customise international health data standards to the local needs. The current status of, and future plans for,…

  4. A Longitudinal Study of Language and Speech in Children Who Were Internationally Adopted at Different Ages

    ERIC Educational Resources Information Center

    Glennen, Sharon

    2014-01-01

    Purpose: The author followed 56 internationally adopted children during the first 3 years after adoption to determine how and when they reached age-expected language proficiency in Standard American English. The influence of age of adoption was measured, along with the relationship between early and later language and speech outcomes. Method:…

  5. 45 CFR 162.910 - Maintenance of standards and adoption of modifications and new standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Maintenance of standards and adoption of... Transactions § 162.910 Maintenance of standards and adoption of modifications and new standards. (a... of existing standards and adoption of new standards. The Secretary considers a recommendation for...

  6. 45 CFR 162.910 - Maintenance of standards and adoption of modifications and new standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Maintenance of standards and adoption of... Transactions § 162.910 Maintenance of standards and adoption of modifications and new standards. (a... of existing standards and adoption of new standards. The Secretary considers a recommendation for...

  7. International Standardization of Bed Rest Standard Measures

    NASA Technical Reports Server (NTRS)

    Cromwell, Ronita L.

    2010-01-01

    This slide presentation gives an overview of the standardization of bed rest measures. The International Countermeasures Working Group attempted to define and agree internationally on standard measurements for spaceflight based bed rest studies. The group identified the experts amongst several stakeholder agencys. It included information on exercise, muscle, neurological, psychological, bone and cardiovascular measures.

  8. Experiences of school bullying among internationally adopted children: results from the Finnish Adoption (FINADO) Study.

    PubMed

    Raaska, Hanna; Lapinleimu, Helena; Sinkkonen, Jari; Salmivalli, Christina; Matomäki, Jaakko; Mäkipää, Sanna; Elovainio, Marko

    2012-08-01

    This study investigated the prevalence of and factors associated with school bullying and victimization among Finnish international adoptees. The Olweus bully/victim questionnaire was sent to all 9-15-year-old children adopted in Finland between 1985 and 2007 through the mediating organizations officially approved by the Ministry of Social Affairs and Health. The children were identified through official adoption organizations. The response rate in the target sample was 49.4%: the study sample consisted of 364 children (190 girls, 52.2%). The children's background factors and symptoms of reactive attachment disorder (RAD) were evaluated using a FINADO questionnaire. Their learning difficulties and social and language skills were assessed using a standardized parental questionnaire (Five to Fifteen). Of the participants, 19.8% reported victimization by peers while 8% had bullied others. Both victimization and bullying were associated with severe symptoms of RAD at the time of adoption (RR 2.68, 95%CI 1.50-4.77 and RR 2.08, 95%CI 1.17-3.69 for victimization and bullying, respectively). Lack of social skills was associated with victimization (RR 1.74, 95%CI 1.06-2.85) but not independently with being a bully (RR 1.50, 95%CI 0.91-2.45). In a multivariate analysis the child's learning difficulties and language difficulties were not associated with either bullying others or victimization.

  9. Why Your Campus Should Consider Adopting OSF's DCE Standards.

    ERIC Educational Resources Information Center

    Plice, Samuel

    1995-01-01

    Reasons for adopting Open Software Foundation (OSF) standards for distributed computing environments (DCE) within colleges and universities are examined. Adoption would promote interoperability across heterogeneous systems within and between institutions, aid in transition to client/server computing, and facilitate sharing and leveraging across…

  10. Geographies of generation: age restrictions in international adoption

    PubMed Central

    Leinaweaver, Jessaca

    2015-01-01

    International adoption relocates minors, and only minors, from one country to another. The centrality of age to adoptive migration may prevent us from seeing the significance of generation: the prospective parent’s age is also examined and evaluated for its relationship to the child’s age and what this relationship will mean for the creation of a family. Because international adoption results in children crossing borders to enter new kinship formations, the assumptions under which it operate require closer geographical analysis. Generation, or the age range that separates dependents and their caretakers, is a significant but unstated motivator of international adoption policies and practices. This article argues that a normative and biologised sense of intergenerational difference is embedded in international adoption. The presence of generational ideology in national laws and international norms regarding international adoption demonstrate a broader sense in which policies situate more privileged families as acceptable and others as inadequate. I draw material for this analysis from both legal documents and documents which aim to provide interpretation of those laws, with reference to international adoptions from Peru. PMID:26766924

  11. International Lessons about National Standards

    ERIC Educational Resources Information Center

    Schmidt, William H.; Houang, Richard; Shakrani, Sharif

    2009-01-01

    Whether to adopt national standards and tests has long been a subject of lively debate in the United States. With 47 states now participating in the Common Core State Standards Initiative, and a commitment from Education Secretary Arne Duncan to allocate hundreds of millions in stimulus funds to the development of common tests, the country is…

  12. Social Competence in Internationally Adopted and Institutionalized Children

    ERIC Educational Resources Information Center

    Palacios, Jesus; Moreno, Carmen; Roman, Maite

    2013-01-01

    A growing, sizable proportion of school children do not live in conventional family environments. Among these, internationally adopted children have gained increasing visibility in recent years. While other areas of their behavior have been widely explored, little is known about adopted children's social competence and their integration into peer…

  13. The Quiet Migration Redux: International Adoption, Race, and Difference

    PubMed Central

    Leinaweaver, Jessaca B.

    2014-01-01

    Demographers frame international adoption primarily as an unusual kind of migration. This insight offers anthropologists new ways to think about kinship. Drawing on demographic scholarship and anthropological kinship and migration studies, this article develops a new and hybrid approach to international adoption as a complex social process that is both migratory and productive of kinship. Viewing international adoption as a form of migration reveals how the stated “push factors” and actual “pull factors” of international adoption do not align perfectly. Using an anthropological life course perspective, the article then explores how the experiences of these “migrants” and those close to them, over time, are better understood as racialization than solely the product of migration. Looking at adoptees’ lives through a migration lens reveals some of the persistent discomforts that prevent open conversations about racial difference and minority status in an adoptive context, that is, one where children have been caused to migrate, recruited into families. This article draws on data from ethnographic fieldwork with Spanish parents who have adopted Peruvian children to argue that international adoption is a unique form of immigration that produces a minority category within a majority population. PMID:25598546

  14. International reference standards in coagulation.

    PubMed

    Raut, Sanj; Hubbard, Anthony R

    2010-07-01

    Measurement of coagulation factor activity using absolute physico-chemical techniques is not possible and estimation therefore relies on comparative bioassay relative to a reference standard with a known or assigned potency. However the inherent variability of locally prepared and calibrated reference standards can give rise to poor agreement between laboratories and methods. Harmonisation of measurement between laboratories at the international level relies on the availability of a common source of calibration for local reference standards and this is provided by the World Health Organization (WHO) International Standards which define the International Unit for the analyte. This article describes the principles, practices and problems of biological standardisation and the development and use of reference standards for assays of coagulation factors, with particular emphasis on WHO International Standards for both concentrates and plasma.

  15. Energy standards and model codes development, adoption, implementation, and enforcement

    SciTech Connect

    Conover, D.R.

    1994-08-01

    This report provides an overview of the energy standards and model codes process for the voluntary sector within the United States. The report was prepared by Pacific Northwest Laboratory (PNL) for the Building Energy Standards Program and is intended to be used as a primer or reference on this process. Building standards and model codes that address energy have been developed by organizations in the voluntary sector since the early 1970s. These standards and model codes provide minimum energy-efficient design and construction requirements for new buildings and, in some instances, existing buildings. The first step in the process is developing new or revising existing standards or codes. There are two overall differences between standards and codes. Energy standards are developed by a consensus process and are revised as needed. Model codes are revised on a regular annual cycle through a public hearing process. In addition to these overall differences, the specific steps in developing/revising energy standards differ from model codes. These energy standards or model codes are then available for adoption by states and local governments. Typically, energy standards are adopted by or adopted into model codes. Model codes are in turn adopted by states through either legislation or regulation. Enforcement is essential to the implementation of energy standards and model codes. Low-rise residential construction is generally evaluated for compliance at the local level, whereas state agencies tend to be more involved with other types of buildings. Low-rise residential buildings also may be more easily evaluated for compliance because the governing requirements tend to be less complex than for commercial buildings.

  16. Internationally adopted children: a new challenge for pediatricians.

    PubMed

    Cataldo, F; Accomando, S; Porcari, V

    2006-02-01

    Children adopted from abroad by Italian families have increased during the last years. Since 2001 to 2004 they have been more than 10,000, mainly from Eastern Europe, and all indications suggest that they will continue to increase. Most of the internationally adopted children reside in orphanage before adoption where they may experience malnutrition, exposure to infectious diseases, environmental deprivation, neglect. Moreover, their pre-adoptive records are scarcely reliable and their immunization status is not always adequate. The most common long-term problems of internationally adopted children concern developmental and scholastic delay especially if they come from a long and severely deprived institutional setting, precocious puberty and, during adolescence, depressive disorders as well as antisocial behaviours. Inter-country adopted children are at increased risk for health and social problems and have to be recognized as a group of subjects requiring special medical attentions. Specialized centres for internationally adopted children where they could receive medical evaluations upon arrival and a prolonged health follow-up should be set up. PMID:16541007

  17. Information architecture: Standards adoption and retirement process service action plan

    SciTech Connect

    1997-03-01

    The purpose of this Service Action Plan is to announce, as well as provide, a high-level outline of a new Departmental process for the adoption and retirement of information technology standards. This process supports the implementation of a Department of Energy (DOE) Information Architecture. This plan was prepared with the Department of Energy information technology standards customers and stakeholders in mind. The process described in this plan will be serviced primarily by staff from the Office of the Deputy Assistant Secretary for Information Management with assistance from designated program and site Information Technology Standards Points of Contact. We welcome any comments regarding this new Departmental process and encourage the proposal of information technology standards for adoption or retirement.

  18. A longitudinal investigation of children internationally adopted at school age.

    PubMed

    Helder, Emily J; Mulder, Elizabeth; Gunnoe, Marjorie Linder

    2016-01-01

    Most existing research on children adopted internationally has focused on those adopted as infants and toddlers. The current study longitudinally tracked several outcomes, including cognitive, behavioral, emotional, attachment, and family functioning, in 25 children who had been internationally adopted at school age (M = 7.7 years old at adoption, SD = 3.4, range = 4–15 years). We examined the incidence of clinically significant impairments, significant change in outcomes over the three study points, and variables that predicted outcomes over time. Clinically significant impairments in sustained attention, full-scale intelligence, reading, language, executive functioning, externalizing problems, and parenting stress were common, with language and executive functioning impairments present at higher levels in the current study compared with past research focusing on children adopted as infants and toddlers. Over the three study points, significant improvements across most cognitive areas and attachment functioning were observed, though significant worsening in executive functioning and internalizing problems was present. Adoptive family-specific variables, such as greater maternal education, smaller family size, a parenting approach that encouraged age-expected behaviors, home schooling, and being the sole adopted child in the family were associated with greater improvement across several cognitive outcomes. In contrast, decreased parenting stress was predicted by having multiple adopted children and smaller family sizes were associated with greater difficulties with executive functioning. Child-specific variables were also linked to outcomes, with girls displaying worse attachment and poorer cognitive performance and with less time in orphanage care resulting in greater adoption success. Implications for future research and clinical applications are discussed.

  19. Experiences of School Bullying among Internationally Adopted Children: Results from the Finnish Adoption (FINANDO) Study

    ERIC Educational Resources Information Center

    Raaska, Hanna; Lapinleimu, Helena; Sinkkonen, Jari; Salmivalli, Christina; Matomaki, Jaakko; Makipaa, Sanna; Elovainio, Marko

    2012-01-01

    This study investigated the prevalence of and factors associated with school bullying and victimization among Finnish international adoptees. The Olweus bully/victim questionnaire was sent to all 9-15-year-old children adopted in Finland between 1985 and 2007 through the mediating organizations officially approved by the Ministry of Social Affairs…

  20. Initial Special Reports Submitted by Member States on the Action Taken by Them Upon the Recommendation Concerning the International Standardization of Library Statistics, Adopted by the General Conference During its Sixteenth Session. Item 21 of the Provisional Agenda.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    Reports, some only partial, from the member states regarding their action on the topic of international standards for library statistics are presented. The 22 countries represented in this report are: Brazil, Bulgaria, Canada, Cyprus, Cuba, Dahomey, Denmark, Finland, France, Federal Republic of Germany, India, Israel, Japan, Libya, Nepal,…

  1. International standardization of mechanical contraceptives.

    PubMed

    Mellstam, S

    1983-06-01

    At least 12 countries have regulations for condoms, and because of the complicated regulations relating to condoms the International Organization for Standardization (ISO) was asked to create a committee for contraceptives. Its objective is to promote the development of standards throughout the world to help the international exchange of goods and services. Following discussions between the World Health Organization (WHO) and ISO it was decided in 1974 to establish a technical ISO committee that would deal with international standards for mechanical contraceptives, comprising condoms, diaphragms, and IUDs. It was also decided that spermicides and oral contraceptives (OCs) should be excluded from the ISO effort, but that they should fall within the responsibility of WHO. The committee, entitled ISO/TC 157 Mechanical Contraceptives, was represented by 35 member countries in 1982. The object of standardizing condoms is to obtain a satisfactory quality that can be accepted throughout the world. To achieve that purpose, acceptable test methods and associated limit requirements and values must be determined, along with rules for storage, packaging, and labeling. The most important factors in determining condom quality are the need to reach agreement on an acceptable number of holes in the condom and the ability to establish limit values for the mechanical properties of the condom. Specific requirements regarding dimensions, resistance to storage, packaging, labeling, and appropriate storage are also important. Up to 1982 the work of ISO for condoms resulted in 8 published international standards, of which 6 deal with test methods, 1 with packaging and labeling, and 1 with storage. Agreement has also been reached within the ISO committee on an additional 3 draft standards. Due to the comparatively small use of diaphragms, standardization efforts in this area do not have the highest priority. ISO/TC 157 has formulated 10 drafts which are being prepared for distribution to

  2. Adoption

    MedlinePlus

    ... the birth nor adoptive parents know the others' identities. Other adoptions are handled more openly. Open adoptions, ... desire to seek out more information about the identity of the birth family. Most of us (whether ...

  3. 45 CFR 162.910 - Maintenance of standards and adoption of modifications and new standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Maintenance of standards and adoption of modifications and new standards. 162.910 Section 162.910 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... recommendation to the National Committee on Vital and Health Statistics (NCVHS)....

  4. 45 CFR 162.910 - Maintenance of standards and adoption of modifications and new standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Maintenance of standards and adoption of modifications and new standards. 162.910 Section 162.910 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... recommendation to the National Committee on Vital and Health Statistics (NCVHS)....

  5. 45 CFR 162.910 - Maintenance of standards and adoption of modifications and new standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Maintenance of standards and adoption of modifications and new standards. 162.910 Section 162.910 Public Welfare Department of Health and Human Services... recommendation to the National Committee on Vital and Health Statistics (NCVHS)....

  6. 29 CFR 500.101 - Promulgation and adoption of vehicle standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Promulgation and adoption of vehicle standards. 500.101... Workers Motor Vehicle Safety § 500.101 Promulgation and adoption of vehicle standards. (a) General. All.... (d) Adoption of Department of Transportation (DOT) Standards. In accordance with section...

  7. 29 CFR 500.101 - Promulgation and adoption of vehicle standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Promulgation and adoption of vehicle standards. 500.101... Workers Motor Vehicle Safety § 500.101 Promulgation and adoption of vehicle standards. (a) General. All.... (d) Adoption of Department of Transportation (DOT) Standards. In accordance with section...

  8. 29 CFR 500.101 - Promulgation and adoption of vehicle standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Promulgation and adoption of vehicle standards. 500.101... Workers Motor Vehicle Safety § 500.101 Promulgation and adoption of vehicle standards. (a) General. All.... (d) Adoption of Department of Transportation (DOT) Standards. In accordance with section...

  9. 29 CFR 500.101 - Promulgation and adoption of vehicle standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Promulgation and adoption of vehicle standards. 500.101... Workers Motor Vehicle Safety § 500.101 Promulgation and adoption of vehicle standards. (a) General. All.... (d) Adoption of Department of Transportation (DOT) Standards. In accordance with section...

  10. Pre-Adoption Adversity, Maternal Stress, and Behavior Problems at School-Age in International Adoptees

    ERIC Educational Resources Information Center

    Gagnon-Oosterwaal, Noemi; Cossette, Louise; Smolla, Nicole; Pomerleau, Andree; Malcuit, Gerard; Chicoine, Jean-Francois; Belhumeur, Celine; Jeliu, Gloria; Begin, Jean; Seguin, Renee

    2012-01-01

    Internationally adopted children present more behavior problems than non-adopted children and are overrepresented in mental health services. These problems are related to children's pre-adoption environment, but adoptive families' functioning and characteristics may also affect the development of behavior problems in adopted children. The aim of…

  11. Associations between Discussions of Racial and Ethnic Differences in Internationally Adoptive Families and Delinquent Behavior among Korean Adopted Adolescents

    PubMed Central

    Anderson, Kayla N.; Lee, Richard M.; Rueter, Martha A.; Kim, Oh Myo

    2015-01-01

    Internationally adopted adolescents may have more delinquent behavior than non-adopted adolescents. One explanation is these adolescents experience discrimination and loss of culture, and adoptive parents are not adequately addressing these experiences. However, studies have not examined the effects of family discussions of racial and ethnic differences within adoptive families on adopted adolescents’ delinquent behavior. To test this relationship, this study utilized data from 111 U.S. internationally adoptive families with 185 South Korean adopted adolescents (55% female, M age = 17.75). During an observational assessment, families discussed the importance of their racial and ethnic differences, and adolescents completed a delinquent behavior questionnaire. Analysis of covariance showed differences in adolescent delinquent behavior across three ways adoptive families discussed racial and ethnic differences; adolescents whose families acknowledged differences had the fewest mean delinquent behaviors. There were no significant differences in delinquent behavior between adolescents whose families acknowledged or rejected the importance of racial and ethnic differences. However, adopted adolescents whose families held discrepant views of differences had significantly more problem behavior than adolescents whose families either acknowledged or rejected the importance of racial and ethnic differences. Clinicians, adoption professionals, and other parenting specialists should focus on building cohesive family identities about racial and ethnic differences, as discrepant views of differences are associated with the most adoptee delinquent behavior. PMID:25729119

  12. International Evaluation of Neutron Cross Section Standards

    NASA Astrophysics Data System (ADS)

    Carlson, A. D.; Pronyaev, V. G.; Smith, D. L.; Larson, N. M.; Chen, Zhenpeng; Hale, G. M.; Hambsch, F.-J.; Gai, E. V.; Oh, Soo-Youl; Badikov, S. A.; Kawano, T.; Hofmann, H. M.; Vonach, H.; Tagesen, S.

    2009-12-01

    experimental data and improved developments in the methodology of analysis and evaluation. Initial efforts to produce a new evaluation were made by the United States Cross Section Evaluation Working Group which formed a Task Force. It was realized that international cooperation would be needed to produce the evaluation. The Working Party on International Evaluation Cooperation of the Nuclear Energy Agency Nuclear Science Committee formed a Subgroup, and the International Atomic Energy Agency formed a Coordinated Research Project (CRP). These groups worked cooperatively to improve the evaluation process. The major effort in producing the evaluation was through the CRP. The evaluations of the neutron cross section standards were finalized in October 2005. Previous difficulties experienced with a data evaluation problem known as "Peelle's Pertinent Puzzle" create biases in the fit of correlated data, and they have been addressed to reduce this phenomenon. The new evaluations of the cross section standards also include covariance matrices of the uncertainties that contain fully justifiable values. The product of this international effort has been adopted as the neutron standards for ENDF/B-VII.0.

  13. How to Integrate International Financial Reporting Standards into Accounting Programs

    ERIC Educational Resources Information Center

    Singer, Robert A.

    2012-01-01

    It is expected the SEC will require U.S. domestic companies to prepare and file their annual 10Ks in accordance with international financial reporting standards (IFRS) by 2016. Given the probability that the FASB-IASB convergence project (i.e., Norwalk Agreement) will continue subsequent to mandatory adoption, US accounting programs will be…

  14. The Second International Standard for Serum Gonadotrophin*

    PubMed Central

    Bangham, D. R.; Woodward, Patricia M.

    1966-01-01

    In 1961 the WHO Expert Committee on Biological Standardization asked the National Institute for Medical Research, London, to collect and study material to replace the first International Standard for Serum Gonadotrophin, stocks of which were running low. This paper describes the material that was contributed, its distribution into ampoules and the international collaborative assay to compare its biological activity with that of the first International Standard. On the basis of the results obtained the material has been established as the second International Standard for Serum Gonadotrophin, with a potency of 1600 International Units per ampoule. The International Unit for Serum Gonadotrophin is thus defined as the activity contained in 0.003569 mg of the second International Standard for Serum Gonadotrophin. PMID:5297810

  15. Reflections on International Bibliographic Standards.

    ERIC Educational Resources Information Center

    Roberts, W.

    This paper raises questions about many bibliographic standards developed over the past 20 years, and challenges librarians to consider how standards might evolve. A brief overview is given of the aims of Universal Bibliographic Control (UBC) and to some assumptions common to much standardization work in recent years inspired by the concept of UBC.…

  16. Correlates and Predictors of Parenting Stress among Internationally Adopting Mothers: A Longitudinal Investigation

    ERIC Educational Resources Information Center

    Viana, Andres G.; Welsh, Janet A.

    2010-01-01

    This study examined correlates and predictors of parenting stress among internationally adopting (IA) mothers with the goal of expanding the knowledge base on the experiences of adoptive parents. One hundred and forty-three IA mothers completed pre-adoption (Time 0) and six months post-adoption (Time 1) surveys with questions regarding child-,…

  17. Administrative simplification: adoption of a standard for a unique health plan identifier; addition to the National Provider Identifier requirements; and a change to the compliance date for the International Classification of Diseases, 10th Edition (ICD-10-CM and ICD-10-PCS) medical data code sets. Final rule.

    PubMed

    2012-09-01

    This final rule adopts the standard for a national unique health plan identifier (HPID) and establishes requirements for the implementation of the HPID. In addition, it adopts a data element that will serve as an other entity identifier (OEID), or an identifier for entities that are not health plans, health care providers, or individuals, but that need to be identified in standard transactions. This final rule also specifies the circumstances under which an organization covered health care provider must require certain noncovered individual health care providers who are prescribers to obtain and disclose a National Provider Identifier (NPI). Lastly, this final rule changes the compliance date for the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) for diagnosis coding, including the Official ICD-10-CM Guidelines for Coding and Reporting, and the International Classification of Diseases, 10th Revision, Procedure Coding System (ICD-10-PCS) for inpatient hospital procedure coding, including the Official ICD-10-PCS Guidelines for Coding and Reporting, from October 1, 2013 to October 1, 2014. PMID:22950146

  18. Adoptive parenting and attachment: association of the internal working models between adoptive mothers and their late-adopted children during adolescence

    PubMed Central

    Pace, Cecilia S.; Di Folco, Simona; Guerriero, Viviana; Santona, Alessandra; Terrone, Grazia

    2015-01-01

    Introduction: Recent literature has shown that the good outcome of adoption would mostly depend on the quality of adoptive parenting, which is strongly associated with the security of parental internal working models (IWMs) of attachment. Specifically, attachment states-of-mind of adoptive mothers classified as free and autonomous and without lack of resolution of loss or trauma could represent a good protective factor for adopted children, previously maltreated and neglected. While most research on adoptive families focused on pre-school and school-aged children, the aim of this study was to assess the concordance of IWMs of attachment in adoptive dyads during adolescence. Method: Our pilot-study involved 76 participants: 30 adoptive mothers (mean age = 51.5 ± 4.3), and their 46 late-adopted adolescents (mean age = 13.9 ± 1.6), who were all aged 4–9 years old at time of adoption (mean age = 6.3 ± 1.5). Attachment representations of adopted adolescents were assessed by the Friend and Family Interview (FFI), while adoptive mothers’ state-of-mind with respect to attachment was classified by the Adult Attachment Interview (AAI). Adolescents’ verbal intelligence was controlled for. Results: Late-adopted adolescents were classified as follows: 67% secure, 26% dismissing, and 7% preoccupied in the FFI, while their adoptive mothers’ AAI classifications were 70% free-autonomous, 7% dismissing, and 23% unresolved. We found a significant concordance of 70% (32 dyads) between the secure–insecure FFI and AAI classifications. Specifically adoptive mothers with high coherence of transcript and low unresolved loss tend to have late-adopted children with high secure attachment, even if the adolescents’ verbal intelligence made a significant contribution to this prediction. Discussion: Our results provides an empirical contribution to the literature concerning the concordance of attachment in adoptive dyads, highlighting the beneficial impact of highly coherent

  19. 40 CFR 121.25 - Adoption of new water quality standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Adoption of new water quality standards... Administrator § 121.25 Adoption of new water quality standards. (a) In any case where: (1) A license or permit was issued without certification due to the absence of applicable water quality standards; and...

  20. Adopting Standards and Measuring Accountability in Public Education.

    ERIC Educational Resources Information Center

    RRFC Links Newsletter, 1997

    1997-01-01

    This newsletter includes six articles related to the Regional Resource and Federal Centers for Special Education Network and its efforts in the area of standards and accountability. In "Teacher Training and Skills: Necessary Ingredients for Standards and Accountability," John Copenhaver discusses ways in which the Regional Resource and Federal…

  1. Adopting Industry Standards for Control Systems Within Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Young, James Scott; Boulanger, Richard

    2002-01-01

    This paper gives a description of OPC (Object Linking and Embedding for Process Control) standards for process control and outlines the experiences at JSC with using these standards to interface with I/O hardware from three independent vendors. The I/O hardware was integrated with a commercially available SCADA/HMI software package to make up the control and monitoring system for the Environmental Systems Test Stand (ESTS). OPC standards were utilized for communicating with I/O hardware and the software was used for implementing monitoring, PC-based distributed control, and redundant data storage over an Ethernet physical layer using an embedded din-rail mounted PC.

  2. IPDA PDS4 Project: Towards an International Planetary Data Standard

    NASA Astrophysics Data System (ADS)

    Martinez, Santa; Roatsch, Thomas; Capria, Maria Teresa; Heather, David; Yamamoto, Yukio; Hughes, Steven; Stein, Thomas; Cecconi, Baptiste; Prashar, Ajay; Batanov, Oleg; Gopala Krishna, Barla

    2016-07-01

    The International Planetary Data Alliance (IPDA) is an international collaboration of space agencies with the main objective of facilitating discovery, access and use of planetary data managed across international boundaries. For this purpose, the IPDA has adopted the NASA's Planetary Data System (PDS) standard as the de-facto archiving standard, and is working towards the internationalisation of the new generation of the standards, called PDS4. PDS4 is the largest upgrade in the history of the PDS, and is a significant step towards an online, distributed, model-driven and service-oriented architecture international archive. Following the successful deployment of PDS4 to support NASA's LADEE and MAVEN missions, PDS4 was endorsed by IPDA in 2014. This has led to the adoption of PDS4 by a number of international space agencies (ESA, JAXA, ISRO and Roscosmos, among others) for their upcoming missions. In order to closely follow the development of the PDS4 standards and to coordinate the international contribution and participation in its evolution, a group of experts from each international agency is dedicated to review different aspects of the standards and to capture recommendations and requirements to ensure the international needs are met. The activities performed by this group cover the assessment and implementation of all aspects of PDS4, including its use, documentation, tools, validation strategies and information model. This contribution will present the activities carried out by this group and how this partnership between PDS and IPDA provides an excellent foundation towards an international platform for planetary science research.

  3. The Second International Standard for Bacitracin

    PubMed Central

    Lightbown, J. W.; Kogut, M.; Uemura, K.

    1964-01-01

    The National Institute for Medical Research, London, was requested by the WHO Expert Committee on Biological Standardization to establish a second International Standard for Bacitracin since stocks of the first International Standard were running low. A batch of 500 g of zinc bacitracin was obtained in 1962 and was distributed into ampoules in 100-mg amounts and dried in vacuum; the ampoules were then filled with dry nitrogen and sealed. This proposed replacement material has been assayed biologically in terms of the first International Standard in seven laboratories in five countries by means of plate diffusion assays. In spite of a large difference in purity between the first and proposed second standards, the variation in the potencies obtained for the proposed second standard were small, although significant. This material has been established as the second International Standard for Bacitracin with a defined potency of 74 mg. The International Unit of Bacitracin is defined as the activity of 0.01351 mg of the second International Standard for Bacitracin. PMID:14230883

  4. Early deprivation and home basal cortisol levels: a study of internationally adopted children.

    PubMed

    Kertes, Darlene A; Gunnar, Megan R; Madsen, Nicole J; Long, Jeffrey D

    2008-01-01

    Animal studies reveal that early deprivation impairs regulation of the hypothalamic-pituitary-adrenocortical (HPA) axis, potentially increasing vulnerability to stressors throughout life. To examine early deprivation effects on basal HPA axis activity in humans, basal cortisol levels were examined in 164 internationally adopted children who had experienced varying degrees of preadoption deprivation. Duration of institutional care, age at adoption, and parent ratings of preadoption neglect indexed a latent factor of Deprived Care. Adoption measures of height and weight standardized to World Health Organisation norms indexed a latent factor of Growth Delay that was viewed as another reflection of deprivation. Cortisol samples were collected 3.3-11.6 years postadoption (Md = 7.3 years) at home on 3 days approximately 30 min after wakeup and before bedtime. Both early a.m. levels and the decrease in cortisol across the day were examined. A structural equation model revealed that preadoption Deprived Care predicted Growth Delay at adoption and Growth Delay predicted higher morning cortisol levels and a larger diurnal cortisol decrease. PMID:18423090

  5. 40 CFR 121.25 - Adoption of new water quality standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Adoption of new water quality... Administrator § 121.25 Adoption of new water quality standards. (a) In any case where: (1) A license or permit was issued without certification due to the absence of applicable water quality standards; and...

  6. 40 CFR 121.25 - Adoption of new water quality standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Adoption of new water quality... Administrator § 121.25 Adoption of new water quality standards. (a) In any case where: (1) A license or permit was issued without certification due to the absence of applicable water quality standards; and...

  7. 40 CFR 121.25 - Adoption of new water quality standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Adoption of new water quality... Administrator § 121.25 Adoption of new water quality standards. (a) In any case where: (1) A license or permit was issued without certification due to the absence of applicable water quality standards; and...

  8. 40 CFR 121.25 - Adoption of new water quality standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Adoption of new water quality... Administrator § 121.25 Adoption of new water quality standards. (a) In any case where: (1) A license or permit was issued without certification due to the absence of applicable water quality standards; and...

  9. 77 FR 43196 - Minimum Internal Control Standards and Technical Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... their comments. DATES: The comment period for the proposed rules published June 1, 2012, at 77 FR 32444 and 77 FR 32465, is extended. Comments on the proposed rules must be received on or before August 15... COMMISSION 25 CFR Parts 543 and 547 Minimum Internal Control Standards and Technical Standards...

  10. Idaho Adopted Higher Standards to Prepare All Students for College and Careers

    ERIC Educational Resources Information Center

    Willits, Luci

    2014-01-01

    Two years ago the state officially chose to adopt the Common Core State Standards (CCSS) as Idaho's new Core Standards in mathematics and English language arts. For Idaho's students these standards are not only higher but also comparable with those in any other country in the world. These new standards will bring significant changes for…

  11. International Adoption in the U. S: Traumatic Stress and Normal Developmental Responses

    ERIC Educational Resources Information Center

    Wolfgang, Jeff Drayton

    2011-01-01

    The purpose of this paper is to present a review of literature on internationally adopted children in the U.S. that provides context, references for normal development, and describes traumatic stress with children. This gives counselors and other professionals who work with young children and families of international adoption a conceptual…

  12. International Adoption among Families in the United States: Considerations of Social Justice.

    ERIC Educational Resources Information Center

    Hollingsworth, Leslie Doty

    2003-01-01

    The practice of international adoption of children is critiqued, using an egalitarian concept of a distributive method of social justice. From this perspective, international adoption may be perceived as contradictory to principles of social justice by ignoring the social context within which it occurs. Possible solutions are critiqued and…

  13. Children's Drawings: Self-Perception and Family Function in International Adoption

    ERIC Educational Resources Information Center

    Bannon, Brittany L.; Tirella, Linda G.; Miller, Laurie C.

    2016-01-01

    No comprehensive studies have examined the utility of family drawings within the context of international adoption. We examined the relationship of Kinetic Family Drawings by 54 internationally adopted children in the USA (65% female; M age = 8.57 years, SD = 2.1) to demographics, child competencies (Child Behavior Checklist: CBCL/6-18) and…

  14. International Standard Classification of Education. Abridged Edition.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Statistics on Education.

    The International Standard Classification of Education (ISCED) has been designed as an instrument suitable for assembling, compiling, and presenting statistics of education both within individual countries and internationally. The classification is designed for assembling data on current educational phenomena such as enrollment, teaching staff and…

  15. 78 FR 63873 - Minimum Internal Control Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... NIGC published a final rule in the Federal Register called Minimum Internal Control Standards. 64 FR... technology and has substantively amended them numerous times, most recently on September 21, 2012. 77 FR... surveillance standards to Part 543 on February 20, 2013 (78 FR 11793). The Commission received...

  16. Working towards compliance with international standards.

    PubMed

    Brückner, G K

    2004-04-01

    Developing countries are increasingly coming under pressure to improve their delivery of veterinary services as a prerequisite for entering the competitive arena of international trade in animals and animal products. The demands placed on developing countries by predominantly developed countries to comply with international disease prevention standards have also resulted in increasing demands on the financial, human and technological resources of these developing countries. The minimum requirements of the Agreement on the Application of Sanitary and Phytosanitary Measures and the standards, guidelines and recommendations of international standard-setting organisations, such as the OIE (World organisation for animal health), are evaluated in terms of the opportunities embedded within these guidelines for developing countries. Such an evaluation indicates that the rights and obligations contained in these standards, guidelines and recommendations do not necessarily protect only the interests of developed countries but also encourage developing countries to work towards the levels of compliance and disease prevention required by their potential trade partners. The costs of this compliance can be reduced by exploiting more cost-effective alternatives for delivering services, when dictated by budgetary constraints. International organisations have illustrated on many occasions, and through a variety of development programmes, that they do indeed realise their responsibility towards developing countries in the areas of increased capacity building and technical assistance. If international organisations can refocus their interventions on the actual and specific needs of developing countries, then they can help to expedite the process of compliance with international standards. PMID:15200089

  17. International standards in mitigating trade risks.

    PubMed

    Thiermann, A B

    2011-04-01

    This paper describes the role of the World Organisation for Animal Health (OIE), as a science-based and democratic standard-setting organisation that provides guidance on preventing the spread of animal diseases, including zoonoses, in international trade. The World Trade Organization is identified as the international institution with the legal power to encourage adherence to international standards and mediate trade disputes. The importance of assuring good governance and the credibility of national Veterinary Services through a process of official certification is identified as an essential component in the safety of trade. Private-public partnerships and the evolution of responsibilities are also identified as essential for the implementation of health guarantees such as compartmentalisation. The rapid emergence of private standards is described as a potential complement to the implementation of sanitary standards, as long as they are applied globally and in support of the OIE standards. Ultimately, the biggest challenge is for the international community to create the incentives and generate the political will for fair trade and for the universal recognition and application of the established international sanitary standards.

  18. International standards in mitigating trade risks.

    PubMed

    Thiermann, A B

    2011-04-01

    This paper describes the role of the World Organisation for Animal Health (OIE), as a science-based and democratic standard-setting organisation that provides guidance on preventing the spread of animal diseases, including zoonoses, in international trade. The World Trade Organization is identified as the international institution with the legal power to encourage adherence to international standards and mediate trade disputes. The importance of assuring good governance and the credibility of national Veterinary Services through a process of official certification is identified as an essential component in the safety of trade. Private-public partnerships and the evolution of responsibilities are also identified as essential for the implementation of health guarantees such as compartmentalisation. The rapid emergence of private standards is described as a potential complement to the implementation of sanitary standards, as long as they are applied globally and in support of the OIE standards. Ultimately, the biggest challenge is for the international community to create the incentives and generate the political will for fair trade and for the universal recognition and application of the established international sanitary standards. PMID:21809769

  19. 76 FR 62714 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... SECURITY Coast Guard 46 CFR Part 160 RIN 1625-AB46 Lifesaving Equipment: Production Testing and... rulemaking. SUMMARY: The Coast Guard proposes to amend the interim rule addressing lifesaving equipment... liferafts and inflatable buoyant apparatuses with recently adopted international standards...

  20. Accelerating the Adoption of Second-Tier Reach Standards forApplicable Appliance Products in China

    SciTech Connect

    Lin, Jiang; Fridley, David

    2007-03-01

    The minimum energy efficiency standards program for household appliances in China was initiated in 1989. Since 1996, CLASP and its implementing partner, LBNL, have assisted China in developing 11 minimum energy performance standards (MEPS) for 9 products and endorsement labels for 11 products including: refrigerators; air conditioners; clothes washers; televisions; printers; computers; monitors; fax machines; copiers; DVD/VCD players; external power supplies; and set-top boxes (under development). Before 2003, China's traditional approach to standards development involved small increases in efficiency requirements for implementation within 6 months of a standard's approval. Since 2003, China has adopted a new approach in setting MEPS. This new approach involves the development of two tiers of standards--one for initial implementation and a second tier at a more aggressive level of energy efficiency for implementation three to five years later. The second-tier standard is also referred to as a 'reach standard'. Reach standards have now been developed in China for: color TVs; refrigerators; air conditioners; and external power supplies. This report is presented in five sections. After the introduction in Section 1, Section 2 analyzes the distribution of the efficiency of refrigerators and air-conditioners in China based on data collected by the China Energy Label Center for the mandatory energy information label program. The results provide an assessment of the adoption of reach standards for these two products. Section 3 summarizes on-going collaborations with Shanghai related to early local adoption of reach standards, and presents both the impact and an analysis of barriers to the local adoption of reach standard for air-conditioners. Section 4 offers suggestions for local governments on how to move forward in adopting reach standards in their localities and concludes with a summary of the results and a plan for developing local capacity in order to achieve

  1. International standards for brucellosis prevention and management.

    PubMed

    Ragan, V; Vroegindewey, G; Babcock, S

    2013-04-01

    International standards are a crucial element in brucellosis prevention and management. They allow policy-makers, scientists, epidemiologists, laboratories and trade entities to have a common vocabulary for communication and understanding of the disease. These standards cover the entire spectrum of activities from surveillance, testing, prophylaxis, transport and trade to policy development, research and reporting. Developing, adhering to and monitoring standards increases both the effectiveness and efficiency of prevention and management programmes. Creating standards with the input of all stakeholders ensures that the standards do not adversely affect the requirements of any of the multiple parties involved. The World Organisation for Animal Health (OIE), in conjunction with its Member Countries, and through its standing and ad hoc committees plus expert input, has taken a key leadership role in developing and reviewing brucellosis standards. These standards are used to harmonise testing, prevention processes, vaccines and reporting, to support trade and to protect human and animal health. PMID:23837376

  2. 40 CFR 1074.110 - Adoption of California standards by other states.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Adoption of California standards by other states. 1074.110 Section 1074.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... PREEMPTION FOR NONROAD ENGINES AND NONROAD VEHICLES Procedures for Authorization § 1074.110 Adoption...

  3. 40 CFR 1074.110 - Adoption of California standards by other states.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Adoption of California standards by other states. 1074.110 Section 1074.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... PREEMPTION FOR NONROAD ENGINES AND NONROAD VEHICLES Procedures for Authorization § 1074.110 Adoption...

  4. 40 CFR 1074.110 - Adoption of California standards by other states.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Adoption of California standards by other states. 1074.110 Section 1074.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... PREEMPTION FOR NONROAD ENGINES AND NONROAD VEHICLES Procedures for Authorization § 1074.110 Adoption...

  5. 40 CFR 1074.110 - Adoption of California standards by other states.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Adoption of California standards by other states. 1074.110 Section 1074.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... PREEMPTION FOR NONROAD ENGINES AND NONROAD VEHICLES Procedures for Authorization § 1074.110 Adoption...

  6. 40 CFR 1074.110 - Adoption of California standards by other states.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Adoption of California standards by other states. 1074.110 Section 1074.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... PREEMPTION FOR NONROAD ENGINES AND NONROAD VEHICLES Procedures for Authorization § 1074.110 Adoption...

  7. 36 CFR 1011.3 - Do these regulations adopt the Federal Claims Collections Standards?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Collections Standards? This part adopts and incorporates all provisions of the FCCS. This part also supplements the FCCS by prescribing procedures consistent with the FCCS, as necessary and appropriate...

  8. Core Standards and Implementation of the International Planetary Data Alliance

    NASA Astrophysics Data System (ADS)

    Crichton, Daniel

    Solar System exploration in the 21st Century is ushering in a new paradigm with complex missions that are hosting instruments developed and managed by the international scientific community. Over the past decade, the European and United States space agencies have collaborated extensively to share common data standards for planetary science archiving, while, just recently, countries including Japan, India and China are now planning and executing robotic exploration missions of the solar system. The collective results yield an unprecedented volume of data across a large number of missions as compared with the last forty years of exploration. At the same time, resources from any one agency are scarce, requiring agencies to leverage existing standards and tools, where possible, and coordinate release and sharing of scientific data results to the worldwide scientific community. In 2006, the International Planetary Data Alliance (IPDA) was founded which includes representatives on a Steering Committee from major space agencies around the world that are involved in planetary science exploration missions. The purpose of the IPDA is two pronged. First, it is to develop a set of data standards for archiving and sharing scientific data products across international agencies and missions. Second, to develop a set of technical information system standards allowing interoperability between agency data systems. These standards are critical to building compatible archives that will allow for science data from international missions to be both captured and shared in a consistent manner. The Planetary Data System (PDS) has a long history of providing data standards to missions for the explicit purpose of archiving and preserving data. These standards have been adopted by the European Space Agency in developing their Planetary Science Archive. In addition, at the time of the IPDA founding, the PDS Standards are considered the "de facto" standards for capturing and archiving planetary

  9. Why Should Workers Know More about International Labour Standards?

    ERIC Educational Resources Information Center

    Gregor, Zdenek

    1981-01-01

    Discusses the usefulness and importance of international labor standards for workers; workers' participation in the International Labour Organisation's (ILO) standard-setting activities and in the implementation of international labor standards; and the ILO's procedures of supervision. (CT)

  10. 39 CFR 254.1 - Adoption of U.S. Access Board Standards as Postal Service Standards of Facility Accessibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Barriers Act (ABA) “Standards for Facility Accessibility,” the following sections of 36 CFR part 1191... THE ARCHITECTURAL BARRIERS ACT § 254.1 Adoption of U.S. Access Board Standards as Postal Service... Barriers Act, Scoping (which contains ABA Chapter 1, Application and Administration, and ABA Chapter...

  11. International adoption among families in the United States: considerations of social justice.

    PubMed

    Hollingsworth, Leslie Doty

    2003-04-01

    The practice of international adoption of children is critiqued, using Rawls' egalitarian concept of a distributive method of social justice. From this perspective, international adoption may be perceived as contradictory to principles of social justice by ignoring the social context within which it occurs. Social contexts that frequently surround international adoption are severe poverty and the disenfranchisement of the adopted child's biological family; the disenfranchisement of certain children because of their lower social status; gender oppression and discrimination against female children; risk to children's rights to the knowledge of their birth history and parentage; risk to children's rights to identification with their ethnic, cultural, and national group; and practices that may involve abduction, deceit, and trafficking in children. The article presents alternate views, including libertarian and utilitarian perspectives. Solutions from two international conventions are critiqued and implications are discussed for social work policy advocacy, practice, and research. PMID:12718416

  12. International adoption among families in the United States: considerations of social justice.

    PubMed

    Hollingsworth, Leslie Doty

    2003-04-01

    The practice of international adoption of children is critiqued, using Rawls' egalitarian concept of a distributive method of social justice. From this perspective, international adoption may be perceived as contradictory to principles of social justice by ignoring the social context within which it occurs. Social contexts that frequently surround international adoption are severe poverty and the disenfranchisement of the adopted child's biological family; the disenfranchisement of certain children because of their lower social status; gender oppression and discrimination against female children; risk to children's rights to the knowledge of their birth history and parentage; risk to children's rights to identification with their ethnic, cultural, and national group; and practices that may involve abduction, deceit, and trafficking in children. The article presents alternate views, including libertarian and utilitarian perspectives. Solutions from two international conventions are critiqued and implications are discussed for social work policy advocacy, practice, and research.

  13. Acquisition of English Grammatical Morphology by Internationally Adopted Children from China

    ERIC Educational Resources Information Center

    Pierce, Lara J.; Genesee, Fred; Paradis, Johanne

    2013-01-01

    Acquisition of English grammatical morphology was examined in five internationally adopted (IA) children from China (aged 0;10-1;1 at adoption) during the first three years' exposure to English to determine whether acquisition patterns were characteristic of child second language (L2) learners or monolingual first language (L1) learners.…

  14. International Labour Standards. A Workers' Education Manual.

    ERIC Educational Resources Information Center

    International Labour Office, Geneva (Switzerland).

    Concerned with the standard-setting work of the International Labor Organization (ILO), this manual is chiefly intended to provide guidance for worker's education instructors and trade union officials. It contains nine chapters: (1) the ILO origins and history are traced and the structure is explained; (2 & 3) procedures for the origination and…

  15. 77 FR 32444 - Minimum Internal Control Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... Minimum Internal Control Standards. 64 FR 590. The rule added a new part to the Commission's regulations..., 2002 (67 FR 43390), August 12, 2005 (70 FR 47108), and October 10, 2008 (73 FR 60498). In addition to... regulations, and the process NIGC should utilize to make revisions. 75 FR 70680 (Nov. 18, 2010). On April...

  16. An international computer protocol standard is essential

    SciTech Connect

    Marks, J.

    1994-02-01

    This article examines the need for the development of an international communication protocol to avoid building or buying customized interfaces or gateways in order to connect two separate vendor's devices to the same computer. The article discuss the need for standards and details one electric cooperative's experience in converting their automated mapping and facilities management system to EPRI sponsored Utility Communications Architecture.

  17. 78 FR 11793 - Minimum Internal Control Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... Internal Control Standards. 64 FR 590. The rule added a new part to the Commission's regulations... equivalently secure area with comparable controls. (3) Access to the count room during the count must be...) Controlled keys. Controls must be established and procedures implemented to safeguard the use, access,...

  18. 15 CFR 19.3 - Do these regulations adopt the Federal Claims Collection Standards (FCCS)?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Claims Collection Standards (FCCS)? 19.3 Section 19.3 Commerce and Foreign Trade Office of the Secretary... Claims Collection Standards (FCCS)? This Part adopts and incorporates all provisions of the FCCS. This Part also supplements the FCCS by prescribing procedures consistent with the FCCS, as necessary...

  19. 31 CFR 5.3 - Do these regulations adopt the Federal Claims Collection Standards (FCCS)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Federal Claims Collection Standards (FCCS)? 5.3 Section 5.3 Money and Finance: Treasury Office of the... Federal Claims Collection Standards (FCCS)? This part adopts and incorporates all provisions of the FCCS. This part also supplements the FCCS by prescribing procedures consistent with the FCCS, as...

  20. The Common Core State Standards Initiative: An Event History Analysis of State Adoption

    ERIC Educational Resources Information Center

    LaVenia, Mark; Cohen-Vogel, Lora; Lang, Laura B.

    2015-01-01

    Today, with states' near-universal adoption of the Common Core State Standards, the political system has achieved that which was not possible less than 2 decades ago. Just why this is so remains unanswered. Some observers have attributed states' embrace of the standards to the substantial financial incentives that the federal government…

  1. The Adoption and Diffusion of an NHRD Standard: A Conceptual Framework

    ERIC Educational Resources Information Center

    Murphy, Aileen; Garavan, Thomas N.

    2009-01-01

    This article proposes a conceptual framework to explain the adoption and diffusion of a national human resource development (NHRD) standard. NHRD standards are used by governments to promote training and development in organizations and increase the professionalization of practices used by organizations. Institutional theory suggests that adoption…

  2. The Voices of Non-Adopters: Members of the Virginia and Nebraska State Boards of Education on Why Their States Did Not Adopt the Common Core Standards

    ERIC Educational Resources Information Center

    State Education Standard, 2012

    2012-01-01

    On June 24, 2010, the Virginia Board of Education unanimously adopted a statement expressing its continuing commitment to Virginia's Standards of Learning (SOL) and opposition to making participation in federal grant and entitlement programs contingent on word-for-word adoption of the newly developed Common Core State Standards in reading and…

  3. Understanding the Perception of Very Small Software Companies towards the Adoption of Process Standards

    NASA Astrophysics Data System (ADS)

    Basri, Shuib; O'Connor, Rory V.

    This paper is concerned with understanding the issues that affect the adoption of software process standards by Very Small Entities (VSEs), their needs from process standards and their willingness to engage with the new ISO/IEC 29110 standard in particular. In order to achieve this goal, a series of industry data collection studies were undertaken with a collection of VSEs. A twin track approach of a qualitative data collection (interviews and focus groups) and quantitative data collection (questionnaire) were undertaken. Data analysis was being completed separately and the final results were merged, using the coding mechanisms of grounded theory. This paper serves as a roadmap for both researchers wishing to understand the issues of process standards adoption by very small companies and also for the software process standards community.

  4. Guidelines International Network: toward international standards for clinical practice guidelines.

    PubMed

    Qaseem, Amir; Forland, Frode; Macbeth, Fergus; Ollenschläger, Günter; Phillips, Sue; van der Wees, Philip

    2012-04-01

    Guideline development processes vary substantially, and many guidelines do not meet basic quality criteria. Standards for guideline development can help organizations ensure that recommendations are evidence-based and can help users identify high-quality guidelines. Such organizations as the U.S. Institute of Medicine and the United Kingdom's National Institute for Health and Clinical Excellence have developed recommendations to define trustworthy guidelines within their locales. Many groups charged with guideline development find the lengthy list of standards developed by such organizations to be aspirational but infeasible to follow in entirety. Founded in 2002, the Guidelines International Network (G-I-N) is a network of guideline developers that includes 93 organizations and 89 individual members representing 46 countries. The G-I-N board of trustees recognized the importance of guideline development processes that are both rigorous and feasible even for modestly funded groups to implement and initiated an effort toward consensus about minimum standards for high-quality guidelines. In contrast to other existing standards for guideline development at national or local levels, the key components proposed by G-I-N will represent the consensus of an international, multidisciplinary group of active guideline developers. This article presents G-I-N's proposed set of key components for guideline development. These key components address panel composition, decision-making process, conflicts of interest, guideline objective, development methods, evidence review, basis of recommendations, ratings of evidence and recommendations, guideline review, updating processes, and funding. It is hoped that this article promotes discussion and eventual agreement on a set of international standards for guideline development.

  5. Acceptance Factors Influencing Adoption of National Institute of Standards and Technology Information Security Standards: A Quantitative Study

    ERIC Educational Resources Information Center

    Kiriakou, Charles M.

    2012-01-01

    Adoption of a comprehensive information security governance model and security controls is the best option organizations may have to protect their information assets and comply with regulatory requirements. Understanding acceptance factors of the National Institute of Standards and Technology (NIST) Risk Management Framework (RMF) comprehensive…

  6. Analysis of Potential Benefits and Costs of Adopting a Commercial Building Energy Standard in South Dakota

    SciTech Connect

    Belzer, David B.; Cort, Katherine A.; Winiarski, David W.; Richman, Eric E.

    2005-03-04

    The state of South Dakota is considering adopting a commercial building energy standard. This report evaluates the potential costs and benefits to South Dakota residents from requiring compliance with the most recent edition of the ANSI/ASHRAE/IESNA 90.1-2001 Energy Standard for Buildings except Low-Rise Residential Buildings. These standards were developed in an effort to set minimum requirements for the energy efficient design and construction of new commercial buildings. The quantitative benefits and costs of adopting a commercial building energy code are modeled by comparing the characteristics of assumed current building practices with the most recent edition of the ASHRAE Standard, 90.1-2001. Both qualitative and quantitative benefits and costs are assessed in this analysis. Energy and economic impacts are estimated using results from a detailed building simulation tool (Building Loads Analysis and System Thermodynamics [BLAST] model) combined with a Life-Cycle Cost (LCC) approach to assess corresponding economic costs and benefits.

  7. Language difficulties in children adopted internationally: neuropsychological and functional neural correlates.

    PubMed

    Helder, E J; Behen, M E; Wilson, B; Muzik, O; Chugani, H T

    2014-01-01

    Children who have experienced deprivation as a result of orphanage care during early development are at increased risk for a number of cognitive, emotional, and social difficulties (MacLean, 2003). This study examined the neuropsychological and behavioral profile of internationally adopted children with language difficulties, one of the most common cognitive challenges (Behen et al., 2008). In addition to neuropsychological testing, fMRI was utilized to examine activation patterns during expressive fluency and receptive language tasks. In comparison to internationally adopted children without language difficulties and nonadopted controls, participants with language difficulty had worse performance on tasks of verbal memory and reasoning, academic skills, and working memory. Behaviorally, all internationally adopted participants, regardless of language ability, had more parent-reported hyperactivity and impulsivity compared with controls. The fMRI tasks revealed reduced activation in traditional language areas in participants with language difficulty. The impact of early adverse experience on later development is discussed.

  8. Foster care and adoption policy in Romania: suggestions for international intervention.

    PubMed

    Johnson, A K; Edwards, R L; Puwak, H

    1993-01-01

    Building an effective child welfare system is a monumental task facing postrevolution Romania. Following revelations on American and Western European television about the large number of "orphans" in Romania, many couples flocked to that country to adopt children. A significant number of adopted Romanian children were brought to the United States. Some of these children are now evidencing problems that are bringing them to the attention of health and social service agencies. This article examines the macroeconomic policies that led to the institutionalization of a large number of children in Romania. Although institutional care is the current norm, a legal basis exists for building family foster care as an alternative. Romania's new adoption law replaces private adoptions with agency-based work. International adoption agencies are involved in developing community-based foster care and permanency planning as part of their work. This article challenges international adoption agencies to use clinical assessments of developmental delays and more rigorous health examinations for children released for adoption.

  9. Cultural identity and internationally adopted children: qualitative approach to parental representations.

    PubMed

    Harf, Aurélie; Skandrani, Sara; Sibeoni, Jordan; Pontvert, Caroline; Revah-Levy, Anne; Moro, Marie Rose

    2015-01-01

    Approximately 30 000 children are adopted across national borders each year. A review of the literature on the cultural belonging of these internationally adopted children shows substantial differences between the literature from English-speaking countries and that from France and Europe in general. The objective of this study is to start from the discourse of French adoptive parents to explore their representations of their child's cultural belonging and their positions (their thoughts and representations) concerning connections with the child's country of birth and its culture. The study includes 51 French parents who adopted one or more children internationally. Each parent participated in a semi-structured interview, focused on the adoption procedure and their current associations with the child's birth country. The interviews were analyzed according to a qualitative phenomenological method, Interpretative Phenomenological Analysis. The principal themes that emerged from our analysis of the interviews made it possible to classify the parents into three different groups. The first group maintained no association with the child's country of birth and refused any multiplicity of cultural identities. The second group actively maintained regular associations with the child's country of birth and culture and affirmed that their family was multicultural. Finally, the third group adapted their associations with the child's birth country and its culture according to the child's questions and interests. Exploring parental representations of the adopted child enables professionals involved in adoption to provide better support to these families and to do preventive work at the level of family interactions. PMID:25775255

  10. 29 CFR 500.105 - DOT standards adopted by the Secretary.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the purposes of this section has adopted from 49 CFR part 398 the following pertinent standards. (In... conform the language to these regulations): (1) Qualification of drivers or operators (Source: 49 CFR 398... meridian shall not be less than a total of 140 degrees; ability to distinguish colors red, green and...

  11. 29 CFR 500.105 - DOT standards adopted by the Secretary.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the purposes of this section has adopted from 49 CFR part 398 the following pertinent standards. (In... conform the language to these regulations): (1) Qualification of drivers or operators (Source: 49 CFR 398... meridian shall not be less than a total of 140 degrees; ability to distinguish colors red, green and...

  12. 29 CFR 500.105 - DOT standards adopted by the Secretary.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the purposes of this section has adopted from 49 CFR part 398 the following pertinent standards. (In... conform the language to these regulations): (1) Qualification of drivers or operators (Source: 49 CFR 398...) Driving of motor vehicles (Source: 49 CFR 398.4)—(i) Compliance required. Every person shall comply...

  13. 29 CFR 500.105 - DOT standards adopted by the Secretary.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the purposes of this section has adopted from 49 CFR part 398 the following pertinent standards. (In... conform the language to these regulations): (1) Qualification of drivers or operators (Source: 49 CFR 398...) Driving of motor vehicles (Source: 49 CFR 398.4)—(i) Compliance required. Every person shall comply...

  14. 29 CFR 500.105 - DOT standards adopted by the Secretary.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the purposes of this section has adopted from 49 CFR part 398 the following pertinent standards. (In... conform the language to these regulations): (1) Qualification of drivers or operators (Source: 49 CFR 398...) Driving of motor vehicles (Source: 49 CFR 398.4)—(i) Compliance required. Every person shall comply...

  15. Potential Ramifications of Common Core State Standards Adoption on Information Literacy

    ERIC Educational Resources Information Center

    Eubanks, Jacob Paul

    2014-01-01

    As of this writing, 45 United States and four territories have adopted the Common Core State Standards (CCSS). The quick implementation on the part of state policymakers is a marked response to the growing demand for career and college ready high school graduates. Current figures suggest that over the next 15 years the need for post-secondary…

  16. International Standard Reagents for HPV Detection

    PubMed Central

    Pagliusi, Sonia R.; Garland, Suzanne M.

    2007-01-01

    Humam papillomavirus is the commonest genital viral infection in healthy sexually active subjects, and the presence of chronic or persistent HPV types in genital cells may constitute a prognostic marker of underlying, or predict future HPV-associated diseases. A variety of novel tests for detecting the presence of oncogenic HPV types in biological specimens have been reported. These are based on the various stages of infection and viral life cycle. HPV infects squamous epithelium with expression of various gene products intimately linked to epithelial cell differentiation. Hence, there are basically three classes of detectable markers directly derived from HPVs: molecular markers based on detection of nucleic acid sequences, serological markers based on detection of antibodies against viral proteins, and cellular markers based on detection of proteins expressed intracellularly, upon either infection or carcinogenesis. The nature of various assays and the development of international standard reagents for qualitative and quantitative assessment of assay performance are outlined. There is an increasing demand to develop standard tools to assess the quality of HPV detection systems, for regulatory and clinical management purposes. International standard reagents for HPV will help defining the analytical sensitivity and specificity of various detection methods, and will allow assuring that laboratory services used to evaluate disease burden, HPV vaccines, and cancer prevention strategies are accurate and comparable worldwide. The advancement of prophylactic vaccine candidates against HPV infections and related diseases stresses the increasing importance of HPV assays in monitoring the impact of HPV vaccination on disease burden. PMID:17627063

  17. Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases☆

    PubMed Central

    Staat, Mary Allen; Stadler, Laura Patricia; Donauer, Stephanie; Trehan, Indi; Rice, Marilyn; Salisbury, Shelia

    2010-01-01

    Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations. PMID:20937322

  18. Critical factors influencing hospitals' adoption of HL7 version 2 standards: an empirical investigation.

    PubMed

    Lin, Chi-Hung; Lin, I-Chun; Roan, Jin-Sheng; Yeh, Jehn-Shan

    2012-06-01

    Industry predictions focus on future e-hospitals that will integrate all stakeholders into a seamless network, allowing data to be shared. The Health Level Seven (HL7) is a standard for the interchange of data within the healthcare industry. It simplifies communication interfaces and allows the interoperability among heterogeneous applications. Although the benefits of adopting HL7 are well known, only a few hospitals in Taiwan have actually adopted it. What are the reasons behind the hospitals' lack of intention to adopt HL7? Most prior studies on HL7 have focused on technical issues and general overlooked the managerial side. This has caused a lack of understanding of factors influencing hospitals' decision on HL7 adoption. In fact, main reasons behind a hospital's decision on whether to adopt an innovative technology are more often related to organizational than purely technical issues. Hence, we pay our attention to these organizational considerations over HL7 adoption. Based on the Innovation Diffusion Theory, we proposed a research model to explore the critical factors influencing Taiwan hospitals' adoption intention of HL7. 472 questionnaires were distributed to all accredited hospitals in Taiwan and 122 were returned. The valid response rate was 25.21% (119). Factor analysis, logistic regression and Pearson Chi-square test were conducted to verify the research model. The results showed that environmental pressure, top management attitude towards HL7, staff's technology capability, system integrity, and hospital's scale were critical factors influencing hospitals' intention on whether to adopt HL7. The research findings provided the government, the healthcare industry, the hospital administrators and the academia with practical and theoretical references. These factors should be considered in planning promotion plan to encourage hospital adoption of HL7. This study also opens up a new research direction as well as a new viewpoint, and consequentially

  19. IRI, an International Standard for the Ionosphere

    NASA Astrophysics Data System (ADS)

    Bilitza, D.; Reinisch, B.; Triskova, L.; Friedrich, M.

    2003-04-01

    The International Reference Ionosphere (IRI) is a data-based model of the ionosphere that has been steadily improved and updated by a joint working group of the Committee on Space Research and the International Union of Radio Science. We will report about the most recent IRI workshops and the improvements and additions planned for the next version of the model. In particular new models will be included for the D-region electron density (Friedrich et al., 2002), and for the ion densities (Triskova et al., 2003) the latter based on Atmosphere Explorer C, D, E and Intercosmos 24 data. A correction term will be introduced in the topside electron density model to alleviate problems at high solar activities and high altitudes (Bilitza, 2002). A special IRI task groups is working on an occurrence probability model for spread-F (Abdu et al., 2003) for inclusion in IRI. A quantitative description of ionospheric variability (standard deviation from monthly mean) is the goal of a special IRI task force activity at the International Center for Theoretical Physics (Radicella 2002). We will also report about activities to update IRI with actual measurements and thus obtain a more accurate description of the actual ionosphere. A proposal to make the IRI model the ISO standard for the ionosphere is now pending before the International Standardization Organization (ISO). The IRI homepage is at http://nssdc.gsfc.nasa.gov/space/model/ionos/iri.html and a web-interface for computing and plotting IRI parameters can be found at http://nssdc.gsfc.nasa.gov/space/model/models/iri.html . Abdu, M. A., J. R de Souza, I. S. Batista, and J. H. A. Sobral, Equatorial Spread F statistics and their empirical modeling for the IRI: A regional model for the Brazilian longitude sector, Adv. Space Res., in press, 2003. Triskova, L., V. Truhlik and J. Smilauer, An empirical model of ion composition in the outer ionosphere, Adv. Space Res., in press, 2003 Bilitza, D., A Correction for the IRI Topside

  20. Discussions about Racial and Ethnic Differences in Internationally Adoptive Families: Links with Family Engagement, Warmth, & Control

    PubMed Central

    Anderson, Kayla N.; Rueter, Martha A.; Lee, Richard M.

    2015-01-01

    Discussions about racial and ethnic differences may allow international, transracial adoptive families to construct multiracial and/or multiethnic family identities. However, little is known about the ways family communication influences how discussions about racial and ethnic differences occur. This study examined associations between observed family communication constructs, including engagement, warmth, and control, and how adoptive families discuss racial and ethnic differences using a sample of families with adolescent-aged children adopted internationally from South Korea (N = 111 families, 222 adolescents). Using data collected during mid-adolescence and again during late adolescence, higher levels of maternal control and positive adolescent engagement were independently associated with a greater likelihood that family members acknowledged the importance of racial and ethnic differences and constructed a multiracial and/or multiethnic family identity. Adolescent engagement was also related to a greater likelihood that family members disagreed about the importance of racial and ethnic differences, and did not build a cohesive identity about differences. PMID:26648791

  1. Medical Issues in International Adoption and Their Influence on Language Development

    ERIC Educational Resources Information Center

    Ladage, Jennifer S.

    2009-01-01

    As the number of international adoptions has increased over the past 2 decades, so has awareness and understanding of the risks associated with the conditions to which these children have been exposed. Prenatal alcohol and/or drug exposure, infectious diseases, malnutrition, and psychosocial deprivation all contribute to the profound growth and…

  2. Far Away from the Tigers: A Year in the Classroom with Internationally Adopted Children

    ERIC Educational Resources Information Center

    Katch, Jane

    2011-01-01

    Over the past three decades, more than a quarter of a million children have become citizens of the United States through international adoption. Kindergarten teacher Jane Katch recently found herself with three such children in her class: Katya, born in Russia, Jasper, from Cambodia, and Caleb, from Romania. Each child had spent early years in an…

  3. Communication Patterns between Internationally Adopted Children and Their Mothers: Implications for Language Development

    ERIC Educational Resources Information Center

    Gauthier, K.; Genesee, F.; Dubois, M. E.; Kasparian K.

    2013-01-01

    This study presents findings on patterns of communication between internationally adopted children and their mothers in order to better understand the nature of these interactions and their influence on language learning. We examined maternal language use and joint attention behaviors of mothers and their children in 21 mother-child pairs: 10…

  4. Assessment of Impacts from Adopting the 2006 International Energy Conservation Code for Residential Buildings in Wyoming

    SciTech Connect

    Lucas, Robert G.

    2007-10-01

    The state of Wyoming currently does not have a statewide building energy efficiency code for residential buildings. The U.S. Department of Energy has requested Pacific Northwest National Laboratory (PNNL) to estimate the energy savings, economic impacts, and pollution reduction from adopting the 2006 International Energy Conservation Code (IECC). This report addresses the impacts for low-rise residential buildings only.

  5. New Trends and Directions in Ethnic Identity among Internationally Transracially Adopted Persons: Summary of Special Issue

    ERIC Educational Resources Information Center

    Rosnati, Rosa; Pinderhughes, Ellen E.; Baden, Amanda L.; Grotevant, Harold D.; Lee, Richard M.; Mohanty, Jayashree

    2015-01-01

    The collective findings of the six articles in this special issue highlight the importance of ethnic-racial socialization and ethnic identity among international transracial adoptees (ITRAs). A multidimensional developmental phenomenon, ethnic identity intersects with other identities, notably adoptive identity. Family, peers, community, and host…

  6. Desirability of Adopting an International Instrument on the Development of Adult Education.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    The first two pages of the document consist of Item 27 of the provisional agenda for the 1974 session of the UNESCO General Conference regarding the desirability of adopting an international instrument on the development of adult education. The remainder of the document is the report of a Preliminary Study of the Technical and Legal Aspects of the…

  7. Atypical EEG Power Correlates with Indiscriminately Friendly Behavior in Internationally Adopted Children

    ERIC Educational Resources Information Center

    Tarullo, Amanda R.; Garvin, Melissa C.; Gunnar, Megan R.

    2011-01-01

    While effects of institutional care on behavioral development have been studied extensively, effects on neural systems underlying these socioemotional and attention deficits are only beginning to be examined. The current study assessed electroencephalogram (EEG) power in 18-month-old internationally adopted, postinstitutionalized children (n = 37)…

  8. Vitamin D Status and Predictors of Hypovitaminosis D in Internationally Adopted Children

    PubMed Central

    Vierucci, Francesco; Ghetti, Francesca; de Martino, Maurizio; Galli, Luisa

    2016-01-01

    Objectives To evaluate vitamin D status in internationally adopted children at first medical evaluation in Italy and to identify possible risk factors for hypovitaminosis D in this population. Methods 25-hydroxyvitamin D [25(OH)D] levels were analyzed in internationally adopted children consecutively recruited at one Italian Center between 2010 and 2014 as part of the first screening protocol. Demographic, clinical and laboratory data were prospectively collected. Serum 25(OH)D levels <10 ng/mL, <20 ng/mL, and <30 ng/mL were used to define severe vitamin D deficiency, vitamin D deficiency and hypovitaminosis D, respectively. Results 962 internationally adopted children (median age: 5.47 years; IQR:3.14–7.93) were included in the study. Median 25(OH)D level was 22.0 ng/mL (IQR:15.0–30.0 ng/mL); 710/962 (73.8%) children showed hypovitaminosis D (<30 ng/mL), 388/962 (40.3%) had vitamin D deficiency (<20 ng/dL), and 92/962 (9.6%) had severe vitamin D deficiency (<10ng/mL). No case of clinical rickets was observed. Hypovitaminosis D was particularly frequent (>90%) in children adopted from Ethiopia, Peru, India, Bulgaria and Lithuania. At multivariate analysis an increased risk of hypovitaminosis D was found to be associated with: age ≥ 6 years, time spent in Italy ≥ 3 months, blood sample taken in winter, spring or fall, compared to summer. Gender, ethnicity/continent of origin, tubercular infection, intestinal parassitosis and BMI-z-score < -2 were not associated with vitamin D status. Conclusion Hypovitaminosis D is common in internationally adopted children, from all ethnic group. The evaluation of serum 25(OH)D level could be useful early after the adoption to promptly start vitamin D supplementation/treatment if needed. PMID:27685941

  9. Improved nuclear safety through international standards

    NASA Astrophysics Data System (ADS)

    Doctor, S. R.; Moffitt, R. L.; Taylor, T. T.; Trosman, G.

    2000-05-01

    In this shrinking world, what happens in an industry in one country can significantly affect the same industry elsewhere around the globe. In April 1986, a nuclear accident destroyed Unit 4 of Ukraine's Chernobyl nuclear power plant, focusing worldwide attention on the dozens of Soviet-designed reactors still in operation. The Chemobyl accident led to public concerns about all operating nuclear power plants and, in some countries (e.g., Italy and Sweden), to proposals for nationwide plant closures or moratoriums on new construction. However, for most former Soviet Union countries, plant shutdown was and still is not a viable option—the plants produce a significant percentage of each nation's total electricity, and those countries do not have sufficient economic resources to develop alternative power sources. In cooperation with similar programs initiated in Canada, Japan, and western European countries, the U.S. Department of Energy (DOE) is conducting a comprehensive effort to reduce risks at Soviet-designed nuclear power plants until they can be shut down or brought into compliance with international standards. This paper describes DOE-supported initiatives with participating host countries to: • improve reliability and accuracy of nondestructive evaluation equipment used for in-service inspection • transfer technologies and infrastructure to improve in-service inspections • enhance management systems for training and certifying host-country in-service inspection personnel The goal of these initiatives to enhance the use of international standards (ASME, ASNT, European Standards EN, and ISO) in operating and regulatory practices at Soviet-designed nuclear power plants.

  10. International Standards on stability of digital prints

    NASA Astrophysics Data System (ADS)

    Adelstein, Peter Z.

    2010-06-01

    The International Standards Organization (ISO) is a worldwide recognized standardizing body which has responsibility for standards on permanence of digital prints. This paper is an update on the progress made to date by ISO in writing test methods in this area. Three technologies are involved, namely ink jet, dye diffusion thermal transfer (dye-sublimation) and electrophotography. Two types of test methods are possible, namely comparative tests and predictive tests. To date a comparative test on water fastness has been published and final balloting is underway on a comparative test on humidity fastness. Predictive tests are being finalized on thermal stability and pollution susceptibility. The test method on thermal stability is intended to predict the print life during normal aging. One of the testing concerns is that some prints do not show significant image change in practical testing times. The test method on pollution susceptibility only deals with ozone and assumes that the reciprocity law applies. This law assumes that a long time under a low pollutant concentration is equivalent to a short time under the high concentration used in the test procedure. Longer term studies include a predictive test for light stability and the preparation of a material specification. The latter requires a decision about the proper colour target to be used and what constitutes an unacceptable colour change. Moreover, a specification which gives a predictive life is very dependent upon the conditions the print encounters and will only apply to specific levels of temperature, ozone and light.

  11. [Attachment and Cognitive and Motor Development in the First Years after Adoption: A Review of Studies on Internationally Adopted Children from China].

    PubMed

    Juffer, Femmie; Finet, Chloe; Vermeer, Harriet; van den Dries, Linda

    2015-01-01

    Due to early-childhood adversity, adopted children often display delays in their cognitive and motor development and have problems developing secure attachment relationships with their adoptive parents. In this review we present the results of all available studies on the attachment and the cognitive and motor development of internationally adopted children from China in the first years after arriving in the adoptive family. Seven pertinent studies were found, based on five samples examined in the USA, Canada, and the Netherlands. Regarding cognitive and motor development (five studies) the adoptees showed a delayed development at arrival in the adoptive family. As soon as six months after arrival the adoptees were, on average, functioning within normal ranges, although their catch-up to non-adopted children was not yet complete. Two years after arrival the catch-up to non-adopted peers appeared to be complete. Regarding attachment (two studies) observations of attachment six and twelve months after adoption showed less secure and more disorganized attachment for the adopted children compared to the normative distribution of non-adopted children. Two years after adoption, observations of attachment confirmed a catch-up in secure attachment, but the adoptees still displayed more insecure disorganized attachment than children in the norm group.

  12. [Attachment and Cognitive and Motor Development in the First Years after Adoption: A Review of Studies on Internationally Adopted Children from China].

    PubMed

    Juffer, Femmie; Finet, Chloe; Vermeer, Harriet; van den Dries, Linda

    2015-01-01

    Due to early-childhood adversity, adopted children often display delays in their cognitive and motor development and have problems developing secure attachment relationships with their adoptive parents. In this review we present the results of all available studies on the attachment and the cognitive and motor development of internationally adopted children from China in the first years after arriving in the adoptive family. Seven pertinent studies were found, based on five samples examined in the USA, Canada, and the Netherlands. Regarding cognitive and motor development (five studies) the adoptees showed a delayed development at arrival in the adoptive family. As soon as six months after arrival the adoptees were, on average, functioning within normal ranges, although their catch-up to non-adopted children was not yet complete. Two years after arrival the catch-up to non-adopted peers appeared to be complete. Regarding attachment (two studies) observations of attachment six and twelve months after adoption showed less secure and more disorganized attachment for the adopted children compared to the normative distribution of non-adopted children. Two years after adoption, observations of attachment confirmed a catch-up in secure attachment, but the adoptees still displayed more insecure disorganized attachment than children in the norm group. PMID:26645774

  13. Generation of CAR T cells for adoptive therapy in the context of glioblastoma standard of care.

    PubMed

    Riccione, Katherine; Suryadevara, Carter M; Snyder, David; Cui, Xiuyu; Sampson, John H; Sanchez-Perez, Luis

    2015-02-16

    Adoptive T cell immunotherapy offers a promising strategy for specifically targeting and eliminating malignant gliomas. T cells can be engineered ex vivo to express chimeric antigen receptors specific for glioma antigens (CAR T cells). The expansion and function of adoptively transferred CAR T cells can be potentiated by the lymphodepletive and tumoricidal effects of standard of care chemotherapy and radiotherapy. We describe a method for generating CAR T cells targeting EGFRvIII, a glioma-specific antigen, and evaluating their efficacy when combined with a murine model of glioblastoma standard of care. T cells are engineered by transduction with a retroviral vector containing the anti-EGFRvIII CAR gene. Tumor-bearing animals are subjected to host conditioning by a course of temozolomide and whole brain irradiation at dose regimens designed to model clinical standard of care. CAR T cells are then delivered intravenously to primed hosts. This method can be used to evaluate the antitumor efficacy of CAR T cells in the context of standard of care.

  14. Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

    PubMed Central

    Riccione, Katherine; Suryadevara, Carter M.; Snyder, David; Cui, Xiuyu; Sampson, John H.; Sanchez-Perez, Luis

    2016-01-01

    Adoptive T cell immunotherapy offers a promising strategy for specifically targeting and eliminating malignant gliomas. T cells can be engineered ex vivo to express chimeric antigen receptors specific for glioma antigens (CAR T cells). The expansion and function of adoptively transferred CAR T cells can be potentiated by the lymphodepletive and tumoricidal effects of standard of care chemotherapy and radiotherapy. We describe a method for generating CAR T cells targeting EGFRvIII, a glioma-specific antigen, and evaluating their efficacy when combined with a murine model of glioblastoma standard of care. T cells are engineered by transduction with a retroviral vector containing the anti-EGFRvIII CAR gene. Tumor-bearing animals are subjected to host conditioning by a course of temozolomide and whole brain irradiation at dose regimens designed to model clinical standard of care. CAR T cells are then delivered intravenously to primed hosts. This method can be used to evaluate the antitumor efficacy of CAR T cells in the context of standard of care. PMID:25741761

  15. 46 CFR 56.01-5 - Adoption of ASME B31.1 for power piping, and other standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENGINEERING PIPING SYSTEMS AND APPURTENANCES General § 56.01-5 Adoption of ASME B31.1 for power piping, and other standards. (a) Piping systems for ships and barges must be designed, constructed, and inspected in... subchapter. See 46 CFR 56.60-1(b) for the other adopted commercial standards applicable to piping...

  16. 46 CFR 56.01-5 - Adoption of ASME B31.1 for power piping, and other standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENGINEERING PIPING SYSTEMS AND APPURTENANCES General § 56.01-5 Adoption of ASME B31.1 for power piping, and other standards. (a) Piping systems for ships and barges must be designed, constructed, and inspected in... subchapter. See 46 CFR 56.60-1(b) for the other adopted commercial standards applicable to piping...

  17. International standards for optical circuit board fabrication, assembly and measurement

    NASA Astrophysics Data System (ADS)

    Pitwon, Richard; Immonen, Marika; Wang, Kai; Itoh, Hideo; Shioda, Tsuyoshi; Wu, Jinhua; Zhu, Long Xiu; Yan, Hui Juan; Worrall, Alex

    2016-03-01

    The commercial adoption of electro-optical printed circuit board (EOCB) technology will be accelerated by the development of industrial and conformity standards for high volume fabrication, connector assembly and waveguide measurement. In this paper, we introduce international standardisation activities surrounding EOCBs and report on industrial processes developed for the high volume fabrication of complex EOCBs with embedded multimode polymer waveguides including a first connector standard for polymer waveguide termination. We focus on solving a serious historic problem with the measurement of optical waveguide systems, namely the lack of harmonised measurement conditions for optical waveguides, which to this day gives rise to strong inconsistencies in the results of measurements by different parties on the same waveguide. We report on the development of a standard to ensure repeatable measurement of optical waveguides, whereby we demonstrate how the application of a measurement identification system and proposed reference measurement conditions can bring variation in measurement results to within 5%, thereby serving as the basis for a formal reliable optical waveguide measurement methodology.

  18. Linguistic interference between L1 and L2 in internationally adopted children.

    PubMed

    Glennen, Sharon; Rosinsky-Grunhut, Ariella; Tracy, Rachel

    2005-02-01

    Bilingual children learning two languages either simultaneously or successively experience patterns of cross-language interference or facilitation due to similarities and differences between the languages. Internationally adopted toddlers are only truly bilingual for a short period of time because the first language disappears quickly after adoption. Yet residual effects of the disappearing first language might impact patterns of learning the new language. To determine if cross-language patterns affected language learning in very young children, language samples were collected from 23 children adopted from Eastern Europe between 11 and 23 months of age. Samples were collected at 6-month intervals during the first year after adoption, then annually up through age 4. Age and order of acquisition of several grammatical morphemes including V + ing, articles, contracted and uncontracted copulas, and contracted and uncontracted auxiliary were explored. These morphological structures developed in the same sequence observed in monolingual children speaking English and were not notably impacted by cross-linguistic factors from language 1. Guidelines for professionals and parents are discussed.

  19. Transmission of multiple resistant Salmonella Concord from internationally adopted children to their adoptive families and social environment: proposition of guidelines.

    PubMed

    Vanhoof, R; Gillis, P; Stévart, O; Boland, C; Vandenberg, O; Fux, F; Collard, J-M; Bertrand, S

    2012-04-01

    Since 2004, an increasing number of multidrug-resistant Salmonella serovar Concord infections have been isolated in Belgium among children adopted from Ethiopia. The patients or their family were interviewed and the isolates were subtyped. Between 2004 and 2009, a total of 39 Salmonella Concord infections were isolated from patients. Thirty-four isolates presented a multidrug resistance including resistance to extended-spectrum cephalosporins. Thirty-six cases involved children and 30 of these were adopted from Ethiopia. One case was due to contact with an adopted child and for the other 5 cases no direct epidemiological link with Ethiopia could be found, although four isolates displayed the same patterns observed on the adoptees' isolates, strongly suggesting a phylogenetic relationship with the Ethiopian isolates. Our study confirmed the emergence in Europe of S. Concord isolates resistant to third-generation cephalosporin among Ethiopian adoptees. We have demonstrated that transmission (intra- and extra familial) can happen even if the frequency seems to be low. The presence and the transmission of such a multidrug-resistant Salmonella infection constitute a major concern, since such strains could jeopardize classical antibiotic therapy in patients at risk. This study provides useful information for parents adopting children and for their family practitioner.

  20. Adoption of an internal viewpoint following presentations of plan-view diagrams and maps.

    PubMed

    Drummond, Aaron; Tlauka, Michael

    2010-05-01

    This study investigated people's ability to adopt novel imagined viewpoints after studying plan-view diagrams and maps. In two experiments, university students were presented with a plan-view diagram of a character surrounded by nearby objects (Expt 1) or a character within a map of a multi-level shopping centre (Expt 2). Subsequently, participants' spatial knowledge of the diagrams/maps was tested by asking them about the location of six salient objects/places. In both experiments, the analyses of participants' spatial judgments suggested that they had adopted an imagined viewpoint internal to the character. The findings add to our understanding of imagined viewpoint switches along the vertical axis of space.

  1. [Classification of an acute pancreatitis: revision by international consensus in 2012 of classification, adopted in Atlanta].

    PubMed

    Kryvoruchko, I A; Kopchak, V M; Usenko, O Iu; Honcharova, N M; Balaka, S M; Teslenko, S M; Andreieshchev, S A

    2014-09-01

    In 1992 on symposium in Atlanta the general classification of an acute pancreatitis, adopted by world medical society for practical application, was proposed. Due to results of multiple investigations there were enhanced the data about an acute pancreatitis pathophysiology, the organs insufficiency, and improvement of the noninvasive and invasive methods of visualization and treatment, what caused necessity to revise the classification. Web-consultations were conducted in 2007 yr to guarantee a wide participation of pancreatologists. After first meeting the working group have directed the document project to 11 national and international associations of pancreatologists. In 2012 yr the definite conclusions, concerning consensus, were published.

  2. Enabling conformity to international standards within SeaDataNet

    NASA Astrophysics Data System (ADS)

    Schaap, Dick M. A.; Boldrini, Enrico; de Korte, Arjen; Santoro, Mattia; Manzella, Giuseppe; Nativi, Stefano

    2010-05-01

    SeaDataNet objective is to construct a standardized system for managing the large and diverse data sets collected by the oceanographic fleets and the new automatic observation systems. The aim is to network and enhance the currently existing infrastructures, which are the national oceanographic data centres and satellite data centres of 36 countries, active in data collection. The networking of these professional data centres, in a unique virtual data management system will provide integrated data sets of standardized quality on-line. The Common Data Index (CDI) is the middleware service adopted by SeaDataNet for discovery and access of the available data. In order to develop an interoperable and effective system, the use of international de facto and de jure standards is required. In particular the new goal object of this presentation is to introduce and discuss the solutions for making SeaDataNet compliant with the European Union (EU) INSPIRE directive and in particular with its Implementing Rules (IR). The European INSPIRE directive aims to rule the creation of an European Spatial Data Infrastructure (ESDI). This will enable the sharing of environmental spatial information among public sector organisations and better facilitate public access to spatial information across Europe. To ensure that the spatial data infrastructures of the European Member States are compatible and usable in a community and transboundary context, the directive requires that common IRs are adopted in a number of specific areas (Metadata, Data Specifications, Network Services, Data and Service Sharing and Monitoring and Reporting). Often the use of already approved digital geographic information standards is mandated, drawing from international organizations like the Open Geospatial Consortium (OGC) and the International Organization for Standardization (ISO), the latter by means of its Technical Committee 211 (ISO/TC 211). In the context of geographic data discovery a set of mandatory

  3. Is Early Experience Destiny? Review of Research on Long-Term Outcomes following International Adoption with Special Reference to the British Chinese Adoption Study.

    PubMed

    Grant, Margaret; Rushton, Alan; Simmonds, John

    2016-01-01

    The pathway from adverse early experience to adulthood for internationally adopted children is complex in identifying key influences, impacts, and outcomes. This review arose from the authors' involvement in the British Chinese Adoption Study, a recent outcomes study that explored the links between early orphanage care, adoptive experiences, and midadulthood. It differs from previous reviews in focusing on a greater length of time since adoption. Both quantitative and qualitative studies were included to allow for examination of a fuller range of adult-related outcomes rather than mental health scores alone. The sampling, methods, and results of reviewed articles are summarised and a critical commentary is provided. Despite methodological differences and identified strengths and weaknesses, conclusions are drawn on the basis of the evidence available. Special attention is paid to the interpretation of negative outcomes. Findings identify areas that should be explored further in order to gain a fuller understanding of midlife outcomes of people who experienced a poor start in life followed by international adoption. Such studies help in refining lifespan developmental theories.

  4. Is Early Experience Destiny? Review of Research on Long-Term Outcomes following International Adoption with Special Reference to the British Chinese Adoption Study

    PubMed Central

    Grant, Margaret; Rushton, Alan; Simmonds, John

    2016-01-01

    The pathway from adverse early experience to adulthood for internationally adopted children is complex in identifying key influences, impacts, and outcomes. This review arose from the authors' involvement in the British Chinese Adoption Study, a recent outcomes study that explored the links between early orphanage care, adoptive experiences, and midadulthood. It differs from previous reviews in focusing on a greater length of time since adoption. Both quantitative and qualitative studies were included to allow for examination of a fuller range of adult-related outcomes rather than mental health scores alone. The sampling, methods, and results of reviewed articles are summarised and a critical commentary is provided. Despite methodological differences and identified strengths and weaknesses, conclusions are drawn on the basis of the evidence available. Special attention is paid to the interpretation of negative outcomes. Findings identify areas that should be explored further in order to gain a fuller understanding of midlife outcomes of people who experienced a poor start in life followed by international adoption. Such studies help in refining lifespan developmental theories. PMID:27247964

  5. Social connectedness, conformity, and internalization of societal standards of attractiveness.

    PubMed

    Vartanian, Lenny R; Hopkinson, Meghan M

    2010-01-01

    Internalization of societal standards of attractiveness is known to play a role in the development of body dissatisfaction and disordered eating, and researchers are now working toward identifying factors that influence the internalization of those societal standards. The present study examined to what extent social connectedness and conformity were related to internalization. Female college students (n=300) completed measures of social connectedness, conformity, and internalization, as well as measures of body image concerns, dietary restraint, and bulimic symptoms. Path analysis showed that social connectedness was negatively related to conformity, and that conformity was positively related to internalization. Consistent with past research, internalization predicted body image concerns and dietary restraint, which in turn predicted bulimic symptoms. Conformity appears to be a risk factor for the internalization of societal standards of attractiveness, and could be targeted in efforts to reduce internalization, negative body image, and disordered eating. PMID:19910270

  6. Social connectedness, conformity, and internalization of societal standards of attractiveness.

    PubMed

    Vartanian, Lenny R; Hopkinson, Meghan M

    2010-01-01

    Internalization of societal standards of attractiveness is known to play a role in the development of body dissatisfaction and disordered eating, and researchers are now working toward identifying factors that influence the internalization of those societal standards. The present study examined to what extent social connectedness and conformity were related to internalization. Female college students (n=300) completed measures of social connectedness, conformity, and internalization, as well as measures of body image concerns, dietary restraint, and bulimic symptoms. Path analysis showed that social connectedness was negatively related to conformity, and that conformity was positively related to internalization. Consistent with past research, internalization predicted body image concerns and dietary restraint, which in turn predicted bulimic symptoms. Conformity appears to be a risk factor for the internalization of societal standards of attractiveness, and could be targeted in efforts to reduce internalization, negative body image, and disordered eating.

  7. Starting over: a preliminary study of early lexical and syntactic development in internationally adopted preschoolers.

    PubMed

    Geren, Joy; Snedeker, Jesse; Ax, Laura

    2005-02-01

    To explore early language acquisition in internationally adopted preschoolers, we collected parental reports (CDI-2) and speech samples from 14 children adopted from China between the ages of 2 years, 7 months and 5 years, 1 month. Their lexical and syntactic development was qualitatively similar to infants acquiring English as a first language: nouns and social words dominated early vocabularies; verbs and closed-class items became more frequent as vocabulary size increased; and lexical and syntactic development were tightly correlated. This research has several implications for clinicians. First, it demonstrates that parental reports provide valid information during the first year after adoption and could be useful in identifying preschool children in need of further assessment. Nine to 15 months after arrival many children reached the ceiling of the CDI-2, suggesting that this instrument has limited utility after the first year. Finally, the rapid lexical and syntactic growth of these children suggests that many of them may eventually catch up with their native-born peers.

  8. Early experience shapes amygdala sensitivity to race: an international adoption design.

    PubMed

    Telzer, Eva H; Flannery, Jessica; Shapiro, Mor; Humphreys, Kathryn L; Goff, Bonnie; Gabard-Durman, Laurel; Gee, Dylan D; Tottenham, Nim

    2013-08-14

    In the current study, we investigated how complete infant deprivation to out-group race impacts behavioral and neural sensitivity to race. Although monkey models have successfully achieved complete face deprivation in early life, this is typically impossible in human studies. We overcame this barrier by examining youths with exclusively homogenous racial experience in early postnatal development. These were youths raised in orphanage care in either East Asia or Eastern Europe as infants and later adopted by American families. The use of international adoption bolsters confidence of infant exposure to race (e.g., to solely Asian faces or European faces). Participants completed an emotional matching task during functional MRI. Our findings show that deprivation to other-race faces in infancy disrupts recognition of emotion and results in heightened amygdala response to out-group faces. Greater early deprivation (i.e., later age of adoption) is associated with greater biases to race. These data demonstrate how early social deprivation to race shapes amygdala function later in life and provides support that early postnatal development may represent a sensitive period for race perception.

  9. 46 CFR 133.03 - Relationship to international standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Relationship to international standards. 133.03 Section 133.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.03 Relationship to international standards. This subpart and subpart B...

  10. 46 CFR 108.503 - Relationship to international standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Relationship to international standards. 108.503 Section 108.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.503 Relationship to international standards....

  11. 46 CFR 133.03 - Relationship to international standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Relationship to international standards. 133.03 Section 133.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.03 Relationship to international standards. This subpart and subpart B...

  12. 46 CFR 133.03 - Relationship to international standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Relationship to international standards. 133.03 Section 133.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.03 Relationship to international standards. This subpart and subpart B...

  13. 46 CFR 133.03 - Relationship to international standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Relationship to international standards. 133.03 Section 133.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.03 Relationship to international standards. This subpart and subpart B...

  14. 46 CFR 133.03 - Relationship to international standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Relationship to international standards. 133.03 Section 133.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS General § 133.03 Relationship to international standards. This subpart and subpart B...

  15. International standards pertaining to thermography practices, training and certification

    NASA Astrophysics Data System (ADS)

    West Åkerblom, Lisa

    2008-03-01

    American, European and International societies establish standards for individuals and companies within the field of infrared thermography. Historically addressing non-destructive testing (NDT) applications and personnel, standards exist and are being developed within the fields of condition monitoring (CM) and building diagnostics. Incorrect reference to or application of standards and guidelines create widespread market confusion. What type of claim can be made against which standards? Does the standard apply to a company or an individual? To what or whom is the standard intended? Does reference to a standard guarantee compliance or imply quality? How does one become educated or involved in standards? An overview of international standards within the field of thermography (with brief reference to recognizable guidelines and standards such as ASNT SNT-TC-1A and CEN 473), their status and application will be presented.

  16. Language Abilities of Internationally Adopted Children from China during the Early School Years: Evidence for Early Age Effects?

    ERIC Educational Resources Information Center

    Delcenserie, Audrey; Genesee, Fred; Gauthier, Karine

    2013-01-01

    We assessed the language, cognitive, and socioemotional abilities of 27 internationally adopted children from China, adopted by French-speaking parents, 12 of whom had been assessed previously by Gauthier and Genesee. The children were on average 7 years, 10 months old and were matched to nonadopted monolingual French-speaking children on age,…

  17. Whose standard is it, anyway? How the tobacco industry determines the International Organization for Standardization (ISO) standards for tobacco and tobacco products

    PubMed Central

    Bialous, S.; Yach, D.

    2001-01-01

    OBJECTIVE—To describe the extent of the tobacco industry involvement in establishing international standards for tobacco and tobacco products and the industry influence on the International Organization for Standardization (ISO).
METHODS—Analysis of tobacco industry documents made public as part of the settlement of the Minnesota Tobacco Trial and the Master Settlement Agreement. Search words included "ISO", "CORESTA", "Barclay", "compensation and machine smoking", "tar and nicotine deliveries", and the name of key players, in different combinations.
RESULTS—It is clear that the tobacco industry, through the Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA), play a major role in determining the scientific evidence and suggesting the standards that are eventually adopted as international standards for tobacco and tobacco products in several areas, including the measurement of cigarette tar and nicotine yield.
CONCLUSIONS—ISO's tobacco and tobacco products standards are not adequate to guide tobacco products regulatory policies, and no health claims can be made based on ISO's tobacco products standards. There is an urgent need for tobacco control advocates and groups worldwide to be more involved with the work of the ISO, both directly and through their national standardisation organisations.


Keywords: tar and nicotine measurement; International Organization for Standardization; ISO; Cooperation Centre for Scientific Research Relative to Tobacco; CORESTA; regulatory policy PMID:11387528

  18. Interrogating Identity: The International Standard School in Indonesia

    ERIC Educational Resources Information Center

    Sakhiyya, Zulfa

    2011-01-01

    This paper examines the impact of the International Standard School (ISS) on the identity of Indonesia as a postcolonial nation. According to the Indonesian Ministry of National Education, an ISS is "a school which complies with the National Standard of Education and enriches its standards from the Organisation for Economic Cooperation and…

  19. International Experience in Standards and Labeling Programs for Rice Cookers

    SciTech Connect

    Zhou, Nan; Zheng, Nina

    2008-05-01

    China has had an active program on energy efficiency standards for household appliances since the mid-1990s. Rice cooker is among the first to be subject to such mandatory regulation, since it is one of the most prevalent electric appliances in Chinese households. Since first introduced in 1989, the minimum energy efficiency standard for rice cookers has not been revised. Therefore, the potential for energy saving is considerable. Initial analysis from CNIS indicates that potential carbon savings is likely to reach 7.6 million tons of CO2 by the 10th year of the standard implementation. Since September 2007, CNIS has been working with various groups to develop the new standard for rice cookers. With The Energy Foundation's support, LBNL has assisted CNIS in the revision of the minimum energy efficiency standard for rice cookers that is expected to be effective in 2009. Specifically, work has been in the following areas: assistance in developing consumer survey on usage pattern of rice cookers, review of international standards, review of international test procedures, comparison of the international standards and test procedures, and assessment of technical options of reducing energy use. This report particularly summarizes the findings of reviewing international standards and technical options of reducing energy consumption. The report consists of an overview of rice cooker standards and labeling programs and testing procedures in Hong Kong, South Korea, Japan and Thailand, and Japan's case study in developing energy efficiency rice cooker technologies and rice cooker efficiency programs. The results from the analysis can be summarized as the follows: Hong Kong has a Voluntary Energy Efficiency Labeling scheme for electric rice cookers initiated in 2001, with revision implemented in 2007; South Korea has both MEPS and Mandatory Energy Efficiency Label targeting the same category of rice cookers as Hong Kong; Thailand's voluntary endorsement labeling program is

  20. Pronuclear scoring. Time for international standardization.

    PubMed

    Zollner, Ursula; Zollner, Klaus-Peter; Steck, Thomas; Dietl, Johannes

    2003-05-01

    Zygote scoring is an efficient tool for embryo selection not only in countries where embryo selection is not permitted. Several different scoring systems have been published so far, making comparisons of assessments between investigators and laboratories extremely difficult. Pronuclear evaluation should be standardized in a manner analogous to the standardization of cleavage stage embryo scoring or of semen evaluation by the World Health Organization. The ideal score should be clear and easily applicable. The items that have the greatest influence on embryonic development seem to be alignment and size of pronuclei, alignment and number of nucleoli, halo effect and appearance of vacuoles. These morphologic parameters can be observed in different features and can be summarized as a zygote score. PMID:12815911

  1. Standardization in laboratory medicine: Adoption of common reference intervals to the Croatian population

    PubMed Central

    Flegar-Meštrić, Zlata; Perkov, Sonja; Radeljak, Andrea

    2016-01-01

    Considering the fact that the results of laboratory tests provide useful information about the state of health of patients, determination of reference value is considered an intrinsic part in the development of laboratory medicine. There are still huge differences in the analytical methods used as well as in the associated reference intervals which could consequently significantly affect the proper assessment of patient health. In a constant effort to increase the quality of patients’ care, there are numerous international initiatives for standardization and/or harmonization of laboratory diagnostics in order to achieve maximum comparability of laboratory test results and improve patient safety. Through the standardization and harmonization processes of analytical methods the ability to create unique reference intervals is achieved. Such reference intervals could be applied globally in all laboratories using methods traceable to the same reference measuring system and analysing the biological samples from the populations with similar socio-demographic and ethnic characteristics. In this review we outlined the results of the harmonization processes in Croatia in the field of population based reference intervals for clinically relevant blood and serum constituents which are in accordance with ongoing activity for worldwide standardization and harmonization based on traceability in laboratory medicine. PMID:27019800

  2. Standardization in laboratory medicine: Adoption of common reference intervals to the Croatian population.

    PubMed

    Flegar-Meštrić, Zlata; Perkov, Sonja; Radeljak, Andrea

    2016-03-26

    Considering the fact that the results of laboratory tests provide useful information about the state of health of patients, determination of reference value is considered an intrinsic part in the development of laboratory medicine. There are still huge differences in the analytical methods used as well as in the associated reference intervals which could consequently significantly affect the proper assessment of patient health. In a constant effort to increase the quality of patients' care, there are numerous international initiatives for standardization and/or harmonization of laboratory diagnostics in order to achieve maximum comparability of laboratory test results and improve patient safety. Through the standardization and harmonization processes of analytical methods the ability to create unique reference intervals is achieved. Such reference intervals could be applied globally in all laboratories using methods traceable to the same reference measuring system and analysing the biological samples from the populations with similar socio-demographic and ethnic characteristics. In this review we outlined the results of the harmonization processes in Croatia in the field of population based reference intervals for clinically relevant blood and serum constituents which are in accordance with ongoing activity for worldwide standardization and harmonization based on traceability in laboratory medicine. PMID:27019800

  3. Similarities and differences between internationally adopted and nonadopted children in their toddler years: Outcomes from a longitudinal study.

    PubMed

    Dalen, Monica; Theie, Steinar

    2014-07-01

    In this study, we compare internationally adopted children's communication, gross motor development, temperament, and challenging behavior with the same characteristics in nonadopted children at age 24 and 36 months. At 24 months, adopted children lag behind in communication and in gross motor development. The adopted children are less active and show less physically challenging behavior. At age 36 months, most of these differences have diminished, but the adopted children still lag behind in communication. This is an important finding because communication skills in the toddler years are a crucial factor in children's attachment, social development, and later language and cognitive development. Looking at the overall outcomes during early toddler years, internationally adopted children are developing very well considering the preadoption adversity to which many of them have been exposed. PMID:24999525

  4. Similarities and differences between internationally adopted and nonadopted children in their toddler years: Outcomes from a longitudinal study.

    PubMed

    Dalen, Monica; Theie, Steinar

    2014-07-01

    In this study, we compare internationally adopted children's communication, gross motor development, temperament, and challenging behavior with the same characteristics in nonadopted children at age 24 and 36 months. At 24 months, adopted children lag behind in communication and in gross motor development. The adopted children are less active and show less physically challenging behavior. At age 36 months, most of these differences have diminished, but the adopted children still lag behind in communication. This is an important finding because communication skills in the toddler years are a crucial factor in children's attachment, social development, and later language and cognitive development. Looking at the overall outcomes during early toddler years, internationally adopted children are developing very well considering the preadoption adversity to which many of them have been exposed.

  5. Biobanking of CSF: international standardization to optimize biomarker development.

    PubMed

    Teunissen, Charlotte E; Tumani, Hayrettin; Engelborghs, Sebastiaan; Mollenhauer, Brit

    2014-03-01

    Cerebrospinal fluid (CSF) reflects pathophysiological aspects of neurological diseases, where neuroprotective strategies and biomarkers are urgently needed. Therefore, biobanking is very relevant for biomarker discovery and evaluation of neurological diseases. Important and unique features of CSF biobanking are intensive collaboration in international networks and the tight application of standardized protocols. The current adoption of standardized protocols for CSF and blood collection as presented in this review enables biomarker studies in large cohorts of patients and controls. Another topic of this review is the selection of control groups, which influences the outcome of biomarker investigations. Control groups in CSF biobanks mainly consist of different disease controls. This is in part due to the fact that lumbar punctures are mostly performed for clinical indications and rarely for research purposes only, as it is a relatively invasive procedure. Moreover, there is a lack of homogenous criteria and definition of control groups. We therefore propose uniform consensus definitions for such control groups in biomarker research, i.e. Healthy controls (HC), Spinal anesthesia subjects (SAS), Symptomatic controls (SC), Inflammatory Neurological Disease Controls (CINDC), Peripheral Inflammatory Neurological Disease Controls (PINDC) and Non-inflammatory Neurological Disease Controls (NINDC). Another important aspect of CSF biobanking is quality control. Systematic studies to address effects of pre-analytical and storage variation on a broad range of CSF proteins are needed. In conclusion, biomarker research in neurodegenerative diseases has entered a new era due to the collaborative and multicenter efforts of many groups. The streamlining of biobanking procedures, including quality control, and the selection of optimal control groups for investigating biomarkers are important improvements to perform high quality biomarker studies.

  6. 78 FR 18321 - International Code Council: The Update Process for the International Codes and Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Fuel Gas Code. International Green Construction Code. International Mechanical Code. ICC Performance... for Residential Construction in High Wind Regions. ICC 700: National Green Building Standard The... proposals from interested individuals and organizations involved in the construction industry as well as...

  7. International environmental management standards (ISO 9000`s less tractable siblings)

    SciTech Connect

    Cascio, J.

    1994-12-31

    Before the advent of ISO 9000 Quality Management standards, the International Organization for Standardization`s (ISO) nearly exclusive focus was on international technical and safety standards. Then, some ten years ago, this staid, Geneva based world standards harmonizer took a fateful step into a more exciting, through considerably less solid realm by impaneling a new technical committee (TC 176) to develop Quality Management standards for organizations. With that, it entered the relatively soft science of organizational management. This initial gamble paid off and resulted in the ISO 9000 series of Quality standards which have won adherents throughout the world and have (in some regions) become requirements of trade. Now, ISO has launched its second sally into the organizational management field by forming Technical Committee 207 to develop yet another set of management standards, this time focusing on the considerably less tractable subject of environmental protection activities within organizations.

  8. Science Education Standards: An International Perspective

    NASA Astrophysics Data System (ADS)

    Orpwood, Graham

    1997-04-01

    The development of standards has become the latest strategy for governments concerned for the quality of education in science to employ in an effort to improve student achievement. In the past five years, not only the US but also Australia, New Zealand, England and Canada have developed new curriculum frameworks for science education. While making clear the expectations for student learning is clearly an important step towards improving achievement, I shall argue that on its own it is not enough and that fundamental change requires levels of public commitment to science and science education that have yet to be realised in the English-speaking democracies.

  9. Using PISA as an International Benchmark in Standard Setting.

    PubMed

    Phillips, Gary W; Jiang, Tao

    2015-01-01

    This study describes how the Programme for International Student Assessment (PISA) can be used to internationally benchmark state performance standards. The process is accomplished in three steps. First, PISA items are embedded in the administration of the state assessment and calibrated on the state scale. Second, the international item calibrations are then used to link the state scale to the PISA scale through common item linking. Third, the statistical linking results are used as part of the state standard setting process to help standard setting panelists determine how high their state standards need to be in order to be internationally competitive. This process was carried out in Delaware, Hawaii, and Oregon, in three subjects-science, mathematics and reading with initial results reported by Phillips and Jiang (2011). An in depth discussion of methods and results are reported in this article for one subject (mathematics) and one state (Hawaii).

  10. 77 FR 37361 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Reciprocating Internal Combustion Engines; New Source Performance Standards for Stationary Internal Combustion... Combustion Engines; New Source Performance Standards for Stationary Internal Combustion Engines.'' The EPA... Internal Combustion Engines; New Source Performance Standards for Stationary......

  11. 77 FR 60341 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Source Performance Standards for Stationary Internal Combustion Engines'' (77 FR 33812). The June 7, 2012... Reciprocating Internal Combustion Engines; New Source Performance Standards for Stationary Internal Combustion... Emission Standards for Hazardous Air Pollutants for Stationary Reciprocating Internal......

  12. Energy and Economic Impacts of U.S. Federal Energy and Water Conservation Standards Adopted From 1987 Through 2010

    SciTech Connect

    Meyers, Stephen; Williams, Alison; Chan, Peter

    2011-12-07

    This paper presents estimates of the key impacts of the energy and water conservation standards that have been adopted from 1987 through 2010. The standards covered include those set by legislation as well as standards adopted by DOE through rulemaking. We estimate that energy efficiency standards for consumer products and certain commercial and industrial equipment that have been adopted from 1987 through 2010 saved 3.0 quads in 2010, have had a cumulative energy savings of 25.9 quads through 2010 and will achieve cumulative energy savings of 158 quads over the period 1990-2070. Thus, the majority of the savings are still to come as products subject to standards enter the stock. Furthermore, the standards will have a cumulative net present value (NPV) of consumer benefit of between $851 billion and $1,103 billion, using 7 percent and 3 percent discount rates, respectively. In addition, we estimate the water conservation standards, together with those energy conservation standards that also save water, saved residential consumers 1.5 trillion gallons of water in 2010, have had cumulative water savings of 11.7 trillion gallons through 2010, and will achieve cumulative water savings by 2040 of 51.4 trillion gallons.

  13. Standardization and harmonization of the blood count: the role of International Committee for Standardization in Haematology (ICSH).

    PubMed

    Lewis, S M

    1990-01-01

    Scientific principles of standardization were first applied in haematology in 1963 when the International Committee for Standardization in Haematology was established with a primary objective to improve the measurement of haemoglobin. Subsequently, ICSH has established Expert Panels on a wide range of haematological topics, including especially a Panel on Cytometry. The purpose of haematological standardization is to obtain precision, accuracy, specificity and harmonization of results between different laboratories in all countries and also between different instruments or methods in the same laboratory. To achieve these objectives ICSH sponsors collaborative studies by scientists from academic centres and from industry and uses a consensus procedure for establishing standards on the basis of the scientific data, followed by an educational programme to ensure that the standards are adopted worldwide. ICSH defines material standards and standardized methods. Material standards are classified as primary international standards, certified reference materials, secondary standards and calibrators. These must be distinguished from control preparations which are intended exclusively for quality control. Standardization of methods must also be considered at four levels: definitive, reference, selected and routine. Each has a place in practice but their roles must be clearly defined. ICSH has an established protocol for evaluation of automated blood cell counters. This defines the levels of precision and accuracy of instrument performance. It is also necessary to assess "clinical utility". The main requirement of the practising haematologist is clinical reliability and harmonization of results for comparability. One of the major functions of ICSH is to provide an interface for collaboration between the manufacturers who develop the instruments and the users in order to achieve this goal.

  14. Human Rights and Values Education: Using the International Standards.

    ERIC Educational Resources Information Center

    Reardon, Betty A.

    1994-01-01

    Asserts that, in teaching about human rights, the international standards should be the fundamental core of the content and values to be communicated. Recommends that teachers should use the Universal Declaration of Human Rights as the standard by which the actions of individuals and governments should be compared. (CFR)

  15. Adaptations of International Standards on Educational Leadership Preparation in Egypt

    ERIC Educational Resources Information Center

    Purinton, Ted; Khalil, Dalia

    2016-01-01

    This paper is a case study of one leadership preparation program, utilizing US school leadership standards and practices, offered in Egypt. This case study illuminates how cultural and policy distinctions impact differing necessities of educational leadership, and how those necessities conflict or concur with the international standards and…

  16. A Proposal for an International Standard Object Number.

    ERIC Educational Resources Information Center

    Austin, David

    1999-01-01

    Discusses extand paradigms (ISBN, ISSN, ISMN, and the emerging ISAN). Models a procedure for assigning ISONs (International Standard Object Number) to objects and their surrogates. Describes resources requisite to the construction of the ISON, and outlines the necessarily cooperative work ahead if an ISON is to become a standard for visual…

  17. The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold.

    PubMed

    Kieft, J S; Zhou, K; Jubin, R; Murray, M G; Lau, J Y; Doudna, J A

    1999-09-24

    Hepatitis C virus (HCV) contains an internal ribosome entry site (IRES) located in the 5' untranslated region of the genomic RNA that drives cap-independent initiation of translation of the viral message. The approximate secondary structure and minimum functional length of the HCV IRES are known, and extensive mutagenesis has established that nearly all secondary structural domains are critical for activity. However, the presence of an IRES RNA tertiary fold and its functional relevance have not been established. Using chemical and enzymatic probes of the HCV IRES RNA in solution, we show that the IRES adopts a unique three-dimensional structure at physiological salt concentrations in the absence of additional cofactors or the translation apparatus. Folding of the IRES involves cooperative uptake of magnesium and is driven primarily by charge neutralization. This tertiary structure contains at least two independently folded regions which closely correspond to putative binding sites for the 40 S ribosomal subunit and initiation factor 3 (eIF3). Point mutations that inhibit IRES folding also inhibit its function, suggesting that the IRES tertiary structure is essential for translation initiation activity. Chemical and enzymatic probing data and small-angle X-ray scattering (SAXS) experiments in solution show that upon folding, the IRES forms an extended structure in which functionally important loops are exposed. These results suggest that the 40 S ribosomal subunit and eIF3 bind an HCV IRES that is prefolded to spatially organize recognition domains.

  18. An International Centre for Standards Documentation: Proposals for Standardization of UDC Usage and the Mechanized Documentation of Information on Standards.

    ERIC Educational Resources Information Center

    Wellisch, Hans

    At present, there are several obstacles to efficient information retrieval regarding the world's standards. There is no uniformity in subject classification, although most standards are classified by the Universal Decimal Classification (UDC); there are no international indexes to the subjects covered; foreign standards and superseded standards…

  19. Pre-adoption adversity and self-reported behavior problems in 7 year-old international adoptees.

    PubMed

    Gagnon-Oosterwaal, Noémi; Cossette, Louise; Smolla, Nicole; Pomerleau, Andrée; Malcuit, Gérard; Chicoine, Jean-François; Jéliu, Gloria; Belhumeur, Céline; Berthiaume, Claude

    2012-08-01

    To further investigate the long-term impact of pre-adoption adversity on international adoptees, externalizing and internalizing symptoms were assessed using a self-report measure at school-age in addition to mothers' reports. The sample consisted of 95 adopted children and their mothers. Children's health and developmental status were assessed soon after arrival in their adoptive family. At age 7, the Dominic Interactive, a self-report measure, was used to evaluate externalizing and internalizing symptoms while mothers completed the CBCL. Children's self-reports were compared to their non-adopted peers'. Adopted children reported more symptoms of specific phobia than their peers. A significant correlation was found between mothers' and children's reports but only for externalizing symptoms. Self-reported symptoms were related to indices of nutritional and psychosocial deprivation at arrival, such as low height/age and weight/height ratios. Our results emphasize the importance of considering international adoptees' perception of their psychological adjustment and the long-term impact of early risk factors.

  20. Collaborative study for the establishment of the 4(th) International Standard for Streptomycin.

    PubMed

    Jorajuria, S; Raphalen, C; Dujardin, V; Daas, A

    2015-01-01

    An international collaborative study was organised to establish the 4(th) World Health Organization (WHO) International Standard (IS) for Streptomycin. Fourteen laboratories from different countries participated. Potencies of the candidate material were estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 3(rd) IS for Streptomycin was used as a reference. Based on the results of the study, the 4(th) IS for Streptomycin was adopted at the meeting of the WHO Expert Committee for Biological Standardization (ECBS) in 2015 with an assigned potency of 76 000 International Units (IU) per vial. The 4(th) IS for Streptomycin is available from the European Directorate for the Quality of Medicines & HealthCare (EDQM).

  1. Barriers to the universal adoption of bilateral internal mammary artery grafting.

    PubMed

    Umakanthan, Jeremiah; Jeyakumar, Panch; Umakanthan, Branavan; Jeyakumar, Nikeshan; Senthilkumar, Nadarajah; Saraswathy, Mathioli R; Umakanthan, Padminidevi; Umakanthan, Janani; Sial, Tamoor; Abrina, Sofia; Buendia, Frances M; Pan, Irene; Kamath, Ramadas K; Pathmarajah, Canagaratnam; Sivalingam, Kanagaratnam; Nathan, Shan A; Sunder, Shun K; Mahendra, Tom; Umakanthan, Ramanan

    2015-04-01

    The left internal mammary artery (LIMA) graft is considered the "gold standard" of coronary artery bypass grafting (CABG). This conduit provides increased survival, symptomatic relief, increased freedom from myocardial infarction, and increased freedom from re-intervention when compared to saphenous venous grafting. It has a remarkable long term patency rate with clinical and angiographic outcomes that are unmatched by other conduits. Given the fact that patients often require more than one graft during a coronary revascularization procedure, the prospect of bilateral internal mammary artery (BIMA) grafting has been very appealing to some surgeons. BIMA grafting has been extensively studied via multiple retrospective and prospective cohort studies and findings have indicated that BIMA grafting can have an increased survival benefit when compared to LIMA grafting alone. As a result, this technique has accrued increasing popularity over the course of the last decade. Yet, questions still remain on whether BIMA grafting is the optimal treatment modality for patients in terms of long-term prognosis. There is limited data at the present time from randomized controlled trials and only 4-12% of CABGs performed today utilize BIMA grafting. Concerns regarding perioperative complications, which patient subsets are at higher risks for complications from the technique, and the technical challenges involved in utilizing and teaching the technique have limited its widespread use. PMID:25644543

  2. Ensuring global standards for medical graduates: a pilot study of international standard-setting.

    PubMed

    Stern, David T; Ben-David, Miriam Friedman; De Champlain, Andre; Hodges, Brian; Wojtczak, Andrzej; Schwarz, M Roy

    2005-05-01

    Increasing physician and patient mobility has led to a move toward internationalization of standards for physician competence. The Institute for International Medical Education proposed a set of outcome-based standards for student performance, which were then measured using three assessment tools in eight leading schools in China: a 150-item multiple-choice examination, a 15-station OSCE and a 16-item faculty observation form. The purpose of this study was to empanel a group of experts to determine whether international student-level performance standards could be set. The IIME convened an international panel of experts in student education with specialty and geographic diversity. The group was split into two, with each sub-group establishing standards independently. After a discussion of the borderline student, the sub-groups established minimally acceptable cut-off scores for performance on the multiple-choice examination (Angoff and Hofstee methods), the OSCE station and global rating performance (modified Angoff method and holistic criterion reference), and faculty observation domains (holistic criterion reference). Panelists within each group set very similar standards for performance. In addition, the two independent parallel panels generated nearly identical performance standards. Cut-off scores changed little before and after being shown pilot data but standard deviations diminished. International experts agreed on a minimum set of competences for medical student performance. In addition, they were able to set consistent performance standards with multiple examination types. This provides an initial basis against which to compare physician performance internationally.

  3. Collaborative study for the establishment of the 3rd international standard for neomycin.

    PubMed

    Rautmann, G; Daas, A; Buchheit, K-H

    2013-01-01

    An international collaborative study was organised to establish the World Health Organization (WHO) 3(rd) International Standard (IS) for neomycin. Ten laboratories from different countries participated in the collaborative study. The potency of the candidate material, a freeze-dried preparation, was estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 2(nd) IS for neomycin was used as a standard. Based on the results of the study, the 3(rd) IS for neomycin was adopted at the meeting of the WHO Expert Committee on Biological Standardization (ECBS) in 2012 with an assigned potency of 19,050 IU per vial. The 3(rd) IS for neomycin is available from the European Directorate for the Quality of Medicines & HealthCare (EDQM).

  4. An Approach to Establishing International Quality Standards for Medical Travel

    PubMed Central

    Kácha, Ondřej; Kovács, Beáta E.; McCarthy, Cormac; Schuurmans, Angela A. T.; Dobyns, Christopher; Haller, Elisa; Hinrichs, Saba; Ruggeri, Kai

    2016-01-01

    The number of individuals traveling abroad is increasing annually. The rising popularity of medical travel and the absence of clear minimum quality requirements in this area urgently call for the development of international standards to ensure good practice and patient safety. The aim of this study is to identify the key domains in medical travel where quality standards should be established. Drawing from the evidence-based OECD framework and an extensive literature review, this study proposes three critical areas for consideration: minimum standards of health-care facilities and third-party agencies, financial responsibility, and patient centeredness. Several cultural challenges have been introduced that may pose a barrier to development of the guidelines and should be taken into consideration. Establishing international quality standards in medical travel enhances benefits to patients and providers, which is an urgent necessity given the rapid growth in this industry. PMID:26973825

  5. An Approach to Establishing International Quality Standards for Medical Travel.

    PubMed

    Kácha, Ondřej; Kovács, Beáta E; McCarthy, Cormac; Schuurmans, Angela A T; Dobyns, Christopher; Haller, Elisa; Hinrichs, Saba; Ruggeri, Kai

    2016-01-01

    The number of individuals traveling abroad is increasing annually. The rising popularity of medical travel and the absence of clear minimum quality requirements in this area urgently call for the development of international standards to ensure good practice and patient safety. The aim of this study is to identify the key domains in medical travel where quality standards should be established. Drawing from the evidence-based OECD framework and an extensive literature review, this study proposes three critical areas for consideration: minimum standards of health-care facilities and third-party agencies, financial responsibility, and patient centeredness. Several cultural challenges have been introduced that may pose a barrier to development of the guidelines and should be taken into consideration. Establishing international quality standards in medical travel enhances benefits to patients and providers, which is an urgent necessity given the rapid growth in this industry. PMID:26973825

  6. Internationally Adopted Children in the Early School Years: Relative Strengths and Weaknesses in Language Abilities

    ERIC Educational Resources Information Center

    Glennen, Sharon

    2015-01-01

    Purpose: This study aimed to determine the relative strengths and weaknesses in language and verbal short-term memory abilities of school-age children who were adopted from Eastern Europe. Method: Children adopted between 1;0 and 4;11 (years;months) of age were assessed with the Clinical Evaluation of Language Fundamentals-Preschool, Second…

  7. The Adoption of Internal Audit as a Governance Control Mechanism in Australian Public Universities--Views from the CEOs

    ERIC Educational Resources Information Center

    Christopher, Joe

    2012-01-01

    This study draws on the multi-theoretical approach to governance and the views of university chief executive officers (CEOs) to examine the extent to which internal auditing as a control mechanism is adopted in Australian public universities under an environment of change management. The findings highlight negative consequences of change and their…

  8. "We-Research": Adopting a Wiki to Support the Processes of Collaborative Research among a Team of International Researchers

    ERIC Educational Resources Information Center

    Young, Susan; Perez, Jessica

    2012-01-01

    This article discusses the adoption of a wiki to support the processes of collaborative research between members of an international team involved in the project MyPlace: MyMusic. The focus is on how new technological communications, here specifically the wiki, can enable and transform the methods and processes of research. We propose two main…

  9. Fulfilling the Promise of the Common Core State Standards: Moving from Adoption to Implementation to Sustainability

    ERIC Educational Resources Information Center

    ASCD, 2012

    2012-01-01

    First launched in April 2009, the Common Core State Standards Initiative was conceived to identify and develop college- and career-readiness standards that address what students are expected to know and be able to do when they have graduated from high school. The initiative introduced the final version of the standards in June 2010, and by…

  10. 77 FR 27490 - Plant-Specific Adoption, Revision 4 of the Improved Standard Technical Specifications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... Electric Plants, BWR/4,'' and NUREG-1434, ``Standard Technical Specifications, General Electric Plants, BWR... ML12104A193 (Bases), and NUREG-1434, ``Standard Technical Specifications, General Electric Plants, BWR/6... ML12104A193 Specifications, General Electric BWR/4 Plants'' NUREG-1434, ``Standard Technical...

  11. EPA STANDARDS NETWORK FACT SHEET: ISO 14000: INTERNATIONAL ENVIRONMENTAL MANAGEMENT STANDARDS

    EPA Science Inventory

    This flyer provides an overview of the ISO 14000 series of International standards, supplying a brief history, structure of the Technical Committee (TC) 207, structure of the U.S. Technical Advisory Group (TAG) to ISO TC-207, status of the Standards development as of June 1997, w...

  12. 75 FR 38026 - Medicare Program; Identification of Backward Compatible Version of Adopted Standard for E...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ...- in clock is available for persons wishing to retain a proof of filing by stamping in and retaining an...), the drug being prescribed or dispensed and other drugs listed in the medication history, as well as...'' final rule, published on November 7, 2005 (70 FR 67568). In that final rule we adopted...

  13. 77 FR 22949 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... FR 3328) in which the Secretary of HHS (the Secretary) adopted the ICD-10-CM and ICD-10-PCS (ICD-10... Federal Register on August 22, 2008 (73 FR 49742); ``HIPAA Administrative Simplification: Modification to... Federal Register on August 22, 2008 (73 FR 49796) (hereinafter referred to as the ICD-10 proposed...

  14. IEC International Standards Under Development For Radiation-Generating Devices

    SciTech Connect

    Voytchev, M; Radev, R; Chiaro, P; Thomson, I; Dray, C; Li, J

    2007-12-06

    The International Electrotechnical Commission (IEC) is the leading and oldest global organization with over 100 years history of developing and publishing international standards for all electrical, electronic and related technologies, including radiation detection instrumentation. Subcommittee 45B 'Radiation Protection Instrumentation' of the IEC has recently started the development of two standards on radiation-generating devices. IEC 62463 'Radiation protection instrumentation--X-ray Systems for the Screening of Persons for Security and the Carrying of Illicit Items' is applicable to X-ray systems designed for screening people to detect if they are carrying objects such as weapons, explosives, chemical and biological agents and other concealed items that could be used for criminal purposes, e.g. terrorist use, drug smuggling, etc. IEC 62523 'Radiation protection instrumentation--Cargo/Vehicle radiographic inspection systems' applies to cargo/vehicle imaging inspection systems using accelerator produced X-ray or gamma radiation to obtain images of the screened objects (e.g. cargo containers, transport and passenger vehicles and railroad cars). The objective of both standards is to specify standard requirements and general characteristics and test procedures, as well as, radiation, electrical, environmental, mechanical, and safety requirements and to provide examples of acceptable methods to test these requirements. In particular the standards address the design requirements as they relate to the radiation protection of the people being screened, people who are in the vicinity of the equipment and the operators. The standard IEC 62463 does not deal with the performance requirements for the quality of the object detection. Compliance with the standards requirements will provide the manufacturers with internationally acceptable specifications and the device users with assurance of the rigorous quality and accuracy of the measurements in relation to the radiological

  15. Measles outbreak among internationally adopted children arriving in the United States, February-March 2001.

    PubMed

    2002-12-13

    On February 16, 2001, the Texas Department of Health was notified about a child aged 10 months adopted from orphanage A in China who was taken to a Texas hospital with fever, conjunctivitis, coryza, Koplik spots, and a maculopapular rash. Measles was confirmed by serologic testing. Public health authorities in Texas notified CDC, which then collaborated with health officials in other states to contact other recently adopted children from China and their adoptive families. This report summarizes the results of multistate contact investigations that identified 14 U.S. measles cases and outlines measures taken in the United States and China to control and prevent measles transmission.

  16. International Review of Frameworks for Standard Setting & Labeling Development

    SciTech Connect

    Zhou, Nan; Khanna, Nina Zheng; Fridley, David; Romankiewicz, John

    2012-09-01

    As appliance energy efficiency standards and labeling (S&L) programs reach a broader geographic and product scope, a series of sophisticated and complex technical and economic analyses have been adopted by different countries in the world to support and enhance these growing S&L programs. The initial supporting techno-economic and impact analyses for S&L development make up a defined framework and process for setting and developing appropriate appliance efficiency standards and labeling programs. This report reviews in-depth the existing framework for standards setting and label development in the well-established programs of the U.S., Australia and the EU to identify and evaluate major trends in how and why key analyses are undertaken and to understand major similarities and differences between each of the frameworks.

  17. DEVELOPMENT OF INTERNATIONAL STANDARDS FOR AIR QUALITY MONITORING AND CONTROL

    EPA Science Inventory

    This report presents a description of the activities and accomplishments of the American Society for Testing and Materials' U. S. Technical Advisory Group (TAG) to the International Standards Organization's Technical Committee 146 on Air Quality. The purpose of the TAG is to re...

  18. 46 CFR 199.03 - Relationship to international standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Relationship to international standards. 199.03 Section 199.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS General § 199.03 Relationship to...

  19. 46 CFR 199.03 - Relationship to international standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Relationship to international standards. 199.03 Section 199.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS General § 199.03 Relationship to...

  20. 46 CFR 199.03 - Relationship to international standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Relationship to international standards. 199.03 Section 199.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS General § 199.03 Relationship to...

  1. 46 CFR 199.03 - Relationship to international standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Relationship to international standards. 199.03 Section 199.03 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS General § 199.03 Relationship to...

  2. 78 FR 8431 - Hazardous Materials: Harmonization with International Standards (RRR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 172 RIN 2137-AE87 Hazardous Materials: Harmonization with International Standards (RRR) Correction In rule document 2012-31243 appearing on pages...

  3. 75 FR 19944 - International Code Council: The Update Process for the International Codes and Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... the International Green Construction Code which will become part of the family of 2012 International... proposals from interested individuals and organizations involved in the construction industry as well as the... standards as the basis for developing Federal regulations concerning new and existing construction. The...

  4. Multilevel Linkages between State Standards, Teacher Standards, and Student Achievement: Testing External versus Internal Standards-Based Education Models

    ERIC Educational Resources Information Center

    Lee, Jaekyung; Liu, Xiaoyan; Amo, Laura Casey; Wang, Weichun Leilani

    2014-01-01

    Drawing on national and state assessment datasets in reading and math, this study tested "external" versus "internal" standards-based education models. The goal was to understand whether and how student performance standards work in multilayered school systems under No Child Left Behind Act of 2001 (NCLB). Under the…

  5. International standardization and classification of human papillomavirus types.

    PubMed

    Bzhalava, Davit; Eklund, Carina; Dillner, Joakim

    2015-02-01

    Established Human Papillomavirus (HPV) types, up to HPV202, belong to 49 species in five genera. International standardization in classification and quality standards for HPV type designation and detection is ensured by the International HPV Reference Center. The center i) receives clones of potentially novel HPV types, re-clones and re-sequences them. If confirmed, an HPV type number is assigned and posted on www.hpvcenter.se. ii) distributes reference clone samples, for academic research, under Material Transfer Agreements agreed with the originator. iii) provides preliminary checking of whether new sequences represent novel types iv) issues international proficiency panels for HPV genotyping. The rate of HPV type discovery is increasing, probably because of metagenomic sequencing. γ-genus today contains 79HPV types and 27 species, surpassing ∝ and β genera with 65 and 51HPV types, respectively. Regular issuing of proficiency panels based on HPV reference clones has resulted in global improvement of HPV genotyping services.

  6. Language development in internationally adopted children: a special case of early second language learning.

    PubMed

    Gauthier, Karine; Genesee, Fred

    2011-01-01

    The French language development of children adopted (n=24) from China was compared with that of control children matched for socioeconomic status, sex, and age. The children were assessed at 50 months of age, on average, and 16 months later. The initial assessment revealed that the 2 groups did not differ with respect to socioemotional adjustment or intellectual abilities. However, the adopted children's expressive language skills were significantly lower than those of the nonadopted children at both assessments. The receptive language skills were also significantly weaker for the adopted children at the second assessment. The results are discussed in terms of possible early age-of-acquisition effects that might affect adopted children's ability to acquire a second first language.

  7. Language development in internationally adopted children: a special case of early second language learning.

    PubMed

    Gauthier, Karine; Genesee, Fred

    2011-01-01

    The French language development of children adopted (n=24) from China was compared with that of control children matched for socioeconomic status, sex, and age. The children were assessed at 50 months of age, on average, and 16 months later. The initial assessment revealed that the 2 groups did not differ with respect to socioemotional adjustment or intellectual abilities. However, the adopted children's expressive language skills were significantly lower than those of the nonadopted children at both assessments. The receptive language skills were also significantly weaker for the adopted children at the second assessment. The results are discussed in terms of possible early age-of-acquisition effects that might affect adopted children's ability to acquire a second first language. PMID:21413938

  8. ASTM International Workshop on Standards & Measurements for Tissue Engineering Scaffolds

    PubMed Central

    Simon, Carl G.; Yaszemski, Michael J.; Ratcliffe, Anthony; Tomlins, Paul; Luginbuehl, Reto; Tesk, John A.

    2016-01-01

    The “Workshop on Standards & Measurements for Tissue Engineering Scaffolds” was held on May 21, 2013 in Indianapolis, IN and was sponsored by the ASTM International (ASTM). The purpose of the workshop was to identify the highest priority items for future standards work for scaffolds used in the development and manufacture of tissue engineered medical products (TEMPs). Eighteen speakers and 78 attendees met to assess current scaffold standards and to prioritize needs for future standards. A key finding was that the ASTM TEMPs subcommittees (F04.41-46) have many active “guide” documents for educational purposes, but that few standard “test methods” or “practices” have been published. Overwhelmingly, the most clearly identified need was standards for measuring the structure of scaffolds, followed by standards for biological characterization, including in vitro testing, animal models and cell-material interactions. The third most pressing need was to develop standards for assessing the mechanical properties of scaffolds. Additional needs included standards for assessing scaffold degradation, clinical outcomes with scaffolds, effects of sterilization on scaffolds, scaffold composition and drug release from scaffolds. Discussions also highlighted the need for additional scaffold reference materials and the need to use them for measurement traceability. Finally, dialogue emphasized the needs to promote the use of standards in scaffold fabrication, characterization, and commercialization and to assess the use and impact of standards in the TEMPs community. Many scaffold standard needs have been identified and focus should now turn to generating these standards to support the use of scaffolds in TEMPs. PMID:25220952

  9. 77 FR 49991 - Small Business Size Standards; Adoption of 2012 North American Industry Classification System for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... footnote 1). solar, wind, 1). geothermal, and biomass electric power generation. 238190 Other Foundation, R..., replacing the Standard Industrial Classification (SIC) System, effective October 1, 2000 (65 FR 30836 (May 5... modification, NAICS 2002 (66 FR 3825 (January 16, 2001)), into its table of size standards, effective October...

  10. Energy and Economic Impacts of U.S. Federal Energy and Water Conservation Standards Adopted From 1987 Through 2013

    SciTech Connect

    Meyers, Stephen; Williams, Alison; Chan, Peter

    2014-06-30

    This paper presents estimates of the key impacts of Federal energy and water conservation standards adopted from 1987 through 2013. The standards for consumer products and commercial and industrial equipment include those set by legislation as well as standards adopted by DOE through rulemaking. In 2013, the standards saved an estimated 4.05 quads of primary energy, which is equivalent to 4% of total U.S. energy consumption. The savings in operating costs for households and businesses totaled $56 billion. The average household saved $361 in operating costs as a result of residential and plumbing product standards. The estimated reduction in CO{sub 2} emissions associated with the standards in 2013 was 218 million metric tons, which is equivalent to 4% of total U.S. CO{sub 2} emissions. The estimated cumulative energy savings over the period 1990-2090 amount to 181 quads. Accounting for the increased upfront costs of more-efficient products and the operating cost (energy and water) savings over the products’ lifetime, the standards have a past and projected cumulative net present value (NPV) of consumer benefit of between $1,271 billion and $1,487 billion, using 7 percent and 3 percent discount rates, respectively. The water conservation standards, together with energy conservation standards that also save water, reduced water use by 1.9 trillion gallons in 2013, and will achieve cumulative water savings by 2090 of 55 trillion gallons. The estimated consumer savings in 2013 from reduced water use amounted to $16 billon.

  11. Longitudinal genetic analysis of internalizing and externalizing problem behavior in adopted biologically related and unrelated sibling pairs.

    PubMed

    Huizink, Anja C; van den Berg, Mijke P; van der Ende, Jan; Verhulst, Frank C

    2007-02-01

    To obtain a better understanding of how genetic and environmental processes are involved in the stability and change in problem behavior from early adolescence into adulthood, studies with genetically informative samples are important. The present study used parent-reported data on internalizing and externalizing problem behavior of adoptees at mean ages 12.4, 15.5 and 26.3. In this adoption study adopted biologically related sibling pairs shared on average 50% of their genes and were brought up in the same family environment, whereas adopted biologically unrelated sibling pairs only shared their family environment. The resemblance between these adopted biologically related (N = 106) and unrelated sibling pairs (N=230) was compared and examined over time. We aimed to investigate (1) to what extent are internalizing and externalizing problem behavior stable from early adolescence into adulthood, and (2) whether the same or different genetic and environmental factors affect these problem behaviors at the 3 assessments. Our results show that both internalizing (rs ranging from .34 to .58) and externalizing behavior (rs ranging from .47 to .69) were rather stable over time. For internalizing and externalizing problem behavior it was found that both genetic and shared environmental influences could be modeled by an underlying common factor, which explained variance in problem behavior from early adolescence into adulthood and accounted for stability over time. The nonshared environmental influences were best modeled by a Cholesky decomposition for internalizing behavior, whereas a time-specific influence of the nonshared environment was included in the final model of externalizing behavior.

  12. DEVELOPING THE NATIONAL GEOTHERMAL DATA SYSTEM ADOPTION OF CKAN FOR DOMESTIC & INTERNATIONAL DATA DEPLOYMENT

    SciTech Connect

    Clark, Ryan J.; Kuhmuench, Christoph; Richard, Stephen M.

    2013-01-01

    The National Geothermal Data System (NGDS) De- sign and Testing Team is developing NGDS software currently referred to as the “NGDS Node-In-A-Box”. The software targets organizations or individuals who wish to host at least one of the following: • an online repository containing resources for the NGDS; • an online site for creating metadata to register re- sources with the NGDS • NDGS-conformant Web APIs that enable access to NGDS data (e.g., WMS, WFS, WCS); • NDGS-conformant Web APIs that support dis- covery of NGDS resources via catalog service (e.g. CSW) • a web site that supports discovery and under- standing of NGDS resources A number of different frameworks for development of this online application were reviewed. The NGDS Design and Testing Team determined to use CKAN (http://ckan.org/), because it provides the closest match between out of the box functionality and NGDS node-in-a-box requirements. To achieve the NGDS vision and goals, this software development project has been inititated to provide NGDS data consumers with a highly functional inter- face to access the system, and to ease the burden on data providers who wish to publish data in the sys- tem. It is important to note that this software package constitutes a reference implementation. The NGDS software is based on open standards, which means other server software can make resources available, and other client applications can utilize NGDS data. A number of international organizations have ex- pressed interest in the NGDS approach to data access. The CKAN node implementation can provide a sim- ple path for deploying this technology in other set- tings.

  13. International standards for pandemic screening using infrared thermography

    NASA Astrophysics Data System (ADS)

    Pascoe, D. D.; Ring, E. F.; Mercer, J. B.; Snell, J.; Osborn, D.; Hedley-Whyte, J.

    2010-03-01

    The threat of a virulent strain of influenza, severe acute respiratory syndrome (SARS), tuberculosis, H1N1/A virus (swine flu) and possible mutations are a constant threat to global health. Implementation of pandemic infrared thermographic screening is based on the detection of febrile temperatures (inner canthus of the eyes) that are correlated with an infectious disease. Previous attempts at pandemic thermal screening have experienced problems (e.g. SARS outbreak, Singapore 2003) associated with the deployment plan, implementation and operation of the screening thermograph. Since this outbreak, the International Electrotechnical Commission has developed international standards that set minimum requirements for thermographic system fever screening and procedures that insure reliable and reproducible measurements. These requirements are published in IEC 80601-2-59:2008, Medical electrical equipment - Part 2-59: Particular requirements for the basic safety and essential performance of screening thermographs for human febrile temperature screening. The International Organization for Standardization has developed ISO/TR 13154:2009, Medical Electrical Equipment - which provides deployment, implementation and operational guidelines for identifying febrile humans using a screening thermograph. These new standards includes recommendations for camera calibrations, use of black body radiators, view field, focus, pixels within measurement site, image positioning, and deployment locations. Many current uses of thermographic screening at airports do not take into account critical issues addressed in the new standard, and are operating below the necessary effectiveness and efficiency. These documents, related thermal research, implications for epidemiology screening, and the future impact on medical thermography are discussed.

  14. Early adversity, hypocortisolism, and behavior problems at school entry: A study of internationally adopted children.

    PubMed

    Koss, Kalsea J; Mliner, Shanna B; Donzella, Bonny; Gunnar, Megan R

    2016-04-01

    The hypothalamic-pituitary-adrenal (HPA) axis is influenced by early life adversity; however, less is known about the potential for recovery following marked improvements in care. The present study examined longitudinal changes in children's cortisol reactivity in the laboratory (4 assessments over 2 years) after adoption. Post-institutionalized (N=65) and post-foster care children (N=49) demonstrated blunted reactivity relative to non-adopted peers (N=53). Furthermore, post-institutionalized children exhibited no evidence of expected adaptation to repeated sessions in the 2 years following adoption. As evidenced by blunted cortisol reactivity, flatter diurnal slope, and lower home morning cortisol, we found support for hypocortisolism among children experiencing adverse early care. Hypocortisolism served as a mediator between adversity and teacher-reported attention and externalizing problems during kindergarten. Early adversity appears to contribute to the down-regulation of the HPA axis under both basal and stress conditions. PMID:26773398

  15. Language Development in Internationally Adopted Children: A Special Case of Early Second Language Learning

    ERIC Educational Resources Information Center

    Gauthier, Karine; Genesee, Fred

    2011-01-01

    The French language development of children adopted (n = 24) from China was compared with that of control children matched for socioeconomic status, sex, and age. The children were assessed at 50 months of age, on average, and 16 months later. The initial assessment revealed that the 2 groups did not differ with respect to socioemotional…

  16. Report on the Desirability of Adopting an International Instrument for the Protection of Translators.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This report contains the formal documents leading to the inclusion on the provisional agenda of UNESCO's 1972 General Conference of a discussion considering the desirability of adopting an instrument for the protection of translators. Included in the document is the "Preliminary Study of the Technical and Legal Aspects of Copyright Protection for…

  17. Acquisition of Complement Clitics and Tense Morphology in Internationally Adopted Children Acquiring French

    ERIC Educational Resources Information Center

    Gauthier, K.; Genesee, F.; Kasparian, K.

    2012-01-01

    The present study examined the language development of children adopted from China to examine possible early age effects with respect to their use of complement clitics, lexical diversity and verb morphology. We focused on these aspects of French because they distinguish second language learners of French and native French-speaking children with…

  18. Human exposure standards in the frequency range 1 Hz To 100 kHz: the case for adoption of the IEEE standard.

    PubMed

    Patrick Reilly, J

    2014-10-01

    Differences between IEEE C95 Standards (C95.6-2002 and C95.1-2005) in the low-frequency (1 Hz-100 kHz) and the ICNIRP-2010 guidelines appear across the frequency spectrum. Factors accounting for lack of convergence include: differences between the IEEE standards and the ICNIRP guidelines with respect to biological induction models, stated objectives, data trail from experimentally derived thresholds through physical and biological principles, selection and justification of safety/reduction factors, use of probability models, compliance standards for the limbs as distinct from the whole body, defined population categories, strategies for central nervous system protection below 20 Hz, and correspondence of environmental electric field limits with contact currents. This paper discusses these factors and makes the case for adoption of the limits in the IEEE standards.

  19. Dyadic adjustment and parenting stress in internationally adoptive mothers and fathers: the mediating role of adult attachment dimensions

    PubMed Central

    Salcuni, Silvia; Miconi, Diana; Altoè, Gianmarco; Moscardino, Ughetta

    2015-01-01

    Previous research has shown that a positive marital functioning represents a resource in adoptive families, leading to a decrease in parenting stress, but little is known about the factors mediating such a relationship. This study aimed to explore whether adult attachment avoidance and anxiety mediate the effect of dyadic functioning on parenting stress in 90 internationally adoptive couples (mothers and fathers) who had adopted a child (aged 3–10 years) in the last 36 months. Participants completed self-report measures of dyadic adjustment, adult attachment, and parenting stress. A series of path analyses supported the mediation hypothesis, but differentially for mothers and fathers. Among mothers, there was a direct and negative relationship between dyadic adjustment and parenting stress. In addition, a better dyadic adjustment was related to lower levels of attachment anxiety, which in turn were associated with less parenting stress. Among fathers, increased dyadic adjustment was related to lower levels of attachment avoidance, which in turn were associated with reduced parenting stress. These findings suggest the importance of including both mothers and fathers in adoption research. Adoptive parents could benefit from specific interventions aimed at reducing attachment avoidance and anxiety by supporting parental sense of competence and involvement for mothers and fathers, respectively. PMID:26388799

  20. CTEPP STANDARD OPERATING PROCEDURE FOR PREPARATION OF SURROGATE RECOVERY STANDARD AND INTERNAL STANDARD SOLUTIONS FOR NEUTRAL TARGET ANALYTES (SOP-5.25)

    EPA Science Inventory

    This standard operating procedure describes the method used for preparing internal standard, surrogate recovery standard and calibration standard solutions for neutral analytes used for gas chromatography/mass spectrometry analysis.

  1. Evidence Use and the Common Core Standards Movement: From Problem Definition to Policy Adoption

    ERIC Educational Resources Information Center

    McDonnell, Lorraine M.; Weatherford, M. Stephen

    2013-01-01

    Despite calls for research-based policies, other types of evidence also influence education policy, including personal experience, professional expertise, and normative values. This article focuses on the Common Core State Standards (CCSS) initiative, examining how research use varied over stages of the process and how it was integrated with other…

  2. 77 FR 1555 - Administrative Simplification: Adoption of Standards for Health Care Electronic Funds Transfers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... regulatory history, see the August 22, 2008 (73 FR 49742) proposed rule entitled ``Health Insurance Reform..., 2000 Federal Register (65 FR 50312), we published a final rule entitled ``Health Insurance Reform... Standards'' (74 FR 3296) (hereinafter referred to as the Modifications final rule) that, among other...

  3. Forging Ahead! Teachers Reflect on the Early Adopter Program to Implement the Common Core State Standards

    ERIC Educational Resources Information Center

    Koning, Erin; Houghtby, Beth; Izard, Patrice; Schuler, Jennifer

    2014-01-01

    This "water cooler" column features e-mail conversations between Erin Koning and three teachers--Beth, Jenna, and Patrice--and is a reflection of their participation in a Chicago Public School (CPS), professional development series designed to support the implementation of the Common Core State Standards (CCSS) in grades K-12. At the…

  4. Standardized interventions in international health: Procrustes, where are you now?

    PubMed

    Maher, Dermot

    2009-10-01

    Two opposing views on implementing interventions in international health are represented on the one hand by 'one size doesn't fit all' and on the other by the promotion of standard approaches. Successes in scaling up access to tuberculosis diagnosis and treatment and access to antiretroviral therapy provide examples of the benefits of a standardized approach to disease management. These benefits may be extended to the management of the emerging epidemic of non-communicable diseases in developing countries. An enthusiastic advocate of standardization, Procrustes (a figure in Greek mythology) went to extreme lengths but his tendencies can be a useful reminder that one size may not fit all, but does fit enough. PMID:19708901

  5. Preparing to meet foreign bugs. Travel, immigration, and international adoptions require special precautions.

    PubMed

    Petersen, K

    2001-07-01

    As the world's population becomes increasingly mobile, children are more likely to be exposed to exotic and troublesome pathogens. These exposures raise concerns about protecting not only kids but the general population as well. In this article, Dr Petersen presents ways to avoid illness in children who travel to other parts of the world. She also discusses concerns about communicable disease as it relates to immigration or adoption of foreign-born children, especially those from developing nations.

  6. Associations between early life adversity and executive function in children adopted internationally from orphanages.

    PubMed

    Hostinar, Camelia E; Stellern, Sarah A; Schaefer, Catherine; Carlson, Stephanie M; Gunnar, Megan R

    2012-10-16

    Executive function (EF) abilities are increasingly recognized as an important protective factor for children experiencing adversity, promoting better stress and emotion regulation as well as social and academic adjustment. We provide evidence that early life adversity is associated with significant reductions in EF performance on a developmentally sensitive battery of laboratory EF tasks that measured cognitive flexibility, working memory, and inhibitory control. Animal models also suggest that early adversity has a negative impact on the development of prefrontal cortex-based cognitive functions. In this study, we report EF performance 1 y after adoption in 2.5- to 4-y-old children who had experienced institutional care in orphanages overseas compared with a group of age-matched nonadopted children. To our knowledge, this is the youngest age and the soonest after adoption that reduced EF performance has been shown using laboratory measures in this population. EF reductions in performance were significant above and beyond differences in intelligence quotient. Within the adopted sample, current EF was associated with measures of early deprivation after controlling for intelligence quotient, with less time spent in the birth family before placement in an institution and lower quality of physical/social care in institutions predicting poorer performance on the EF battery.

  7. Guidelines of the Office International des Epizooties for laboratory quality evaluation, for international reference standards for antibody assays and for laboratory proficiency testing.

    PubMed

    1998-08-01

    Three guidelines, adopted by the International Committee of the Office International des Epizooties (OIE), have been combined for publication in a single document. The Guidelines for evaluating laboratory quality (adopted in 1995) form part of the OIE Guidelines for evaluating Veterinary Services. General requirements for equipment, staffing and management of laboratories are outlined. The guidelines for international reference standards for antibody assays (adopted in 1998) provide general rules governing the preparation of immune sera by OIE Reference Laboratories. A data sheet should accompany each preparation dispatched from the laboratory, and details are given of the information to be contained in the data sheet. The guidelines are to be used in conjunction with the OIE Manual of standards for diagnostic tests and vaccines. Guidelines on the proficiency of laboratory testing (adopted in 1996) describe how the operation of a laboratory can be assessed by inter-laboratory testing, and by voluntary participation in an accreditation (quality assurance) audit, operated by an independent authority. Criteria for assessing serological testing are provided.

  8. Oral Radiology Safety Standards Adopted by the General Dentists Practicing in National Capital Region (NCR)

    PubMed Central

    Jayaprakash, K.; Shivalingesh, K.K.; Agarwal, Vartika; Gupta, Bhuvandeep; Anand, Richa; Sharma, Abhinav; Kushwaha, Sumedha

    2016-01-01

    Introduction With advancement in diagnostic techniques, the utilization of radiologic examination has risen to many folds in the last two decades. Ionizing radiations from the radiographic examination carry the potential for harm by inducing carcino-genesis in addition to the diagnostic information extracted. Radiation doses utilized in the course of dental treatment might be low for individual examinations but patients are exposed to repeated examinations very often and many people are exposed during the course of dental care. Therefore, principles of radiation protection and safety are necessary for the dentists to follow to ensure minimum and inevitable exposure. Aim The aim of this study was to investigate the knowledge and behaviour of general dentists practicing in the National Capital Region (NCR) regarding radiation safety during oral radiographic procedures. Materials and Methods The study was a questionnaire based cross-sectional study. A total of 500 general dentists were contacted to participate in the study. The target population entailed of general dentists practicing in the National Capital Region. Data was computed and tabulated in Microsoft excel sheet and statistical analysis was performed with the help of SPSS version 21.0. Results The total response rate recovered was 70.6% and the respondents comprised of 59% and 41% males & females respectively. Only 64.8% of the general dentists contemplated thyroid to be the most important organ for radiation protection. Only 28.8% of the general dentists followed the position & distance rule appropriately. Conclusion The results showed that the knowledge and behaviour of the general dentists and the practices adopted by them regarding radiation safety is not satisfactory. To ensure the following of basic and necessary guidelines for radiation safety and protection, strict rules with penalties should be implemented by the state councils and new and interesting methods of education for this spectrum of the

  9. Evaluation of the feasibility of international growth standards for school-aged children and adolescents.

    PubMed

    Butte, Nancy E; Garza, Cutberto; de Onis, Mercedes

    2006-12-01

    Development of an international growth standard for the screening, surveillance, and monitoring of school-aged children and adolescents has been motivated by two contemporaneous events: the global surge in childhood obesity and the release of a new international growth standard for infants and preschool children by the World Health Organization (WHO). If a prescriptive approach analogous to that taken by WHO for younger children is to be adopted for school-aged children and adolescents, several issues would have to be addressed regarding the universality of growth potential across populations and how to define optimal growth in children and adolescents. A working group concluded that subpopulations exhibit similar patterns of growth when exposed to similar external conditioners of growth. However, on the basis of available data, it cannot be ruled out that some of the observed differences in linear growth across ethnic groups reflect true differences in genetic potential rather than environmental influences. Therefore, the sampling frame for the development of an international growth standard for children and adolescents would have to include multiethnic sampling strategies designed to capture the variation in human growth patterns. A single international growth standard for school-aged children and adolescents could be developed with careful consideration of the population and individual selection criteria, study design, sample size, measurements, and statistical modeling of primary growth and secondary ancillary data. The working group agreed that existing growth references for school-aged children and adolescents have shortcomings, particularly for assessing obesity, and that appropriate growth standards for these age groups should be developed for clinical and public health applications.

  10. Collaborative study for the establishment of the second international standard for gramicidin.

    PubMed

    Rautmann, G; Daas, A; Buchheit, K-H

    2010-10-01

    An international collaborative study was organised by the European Directorate for the Quality of Medicines & HealthCare (EDQM) to establish the WHO second International Standard (IS) for gramicidin as the stocks of the 1st IS, established in 1964, were close to depletion. The candidate material did not show any sign of potency loss when kept at elevated temperatures of + 4 °C, + 20 °C, + 37 °C and + 45 °C for 3 months. Six laboratories from 5 countries as well as the EDQM laboratory participated in the collaborative study. Potencies of the candidate material were estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 1st IS for gramicidin was used as standard. Based on the results of the study, the 2nd IS for gramicidin was adopted at the meeting of the WHO Expert Committee on Biological Standardization (ECBS) in 2008 with an assigned potency of 1070 International Units per mg (IU/mg). The 2nd IS for gramicidin is available from the EDQM.

  11. Five years later: language in school-age internationally adopted children.

    PubMed

    Glennen, Sharon; Bright, Betsy J

    2005-02-01

    This study followed a cohort of 46 school-age children adopted from Eastern Europe who were originally studied by Glennen and Masters up through age 2 or 3. Five years later, the children were 6 to 9 years of age. Data on their school-age abilities were collected through surveys of parents and teachers. Parents indicated that 17.4% of the children were receiving classroom accommodations or special education programs and 54.5% had one or more diagnoses. The most common diagnosis was attention deficit disorder/attention deficit hyperactivity disorder (ADD/ADHD), occurring in 25% of the children, primarily boys. Learning disability and speech language impairment were each noted in 11.4% of the children. Language and Social Skill profiles on the Children's Communication Checklist-2 and Social Skills Rating Scale (SSRS) indicated that structural and meaning-based language abilities were areas of strength. Measures of pragmatic use of language (i.e., Use of Context, Social Relations, Nonverbal Communication) were relative weaknesses. Behavior profiles on the SSRS indicated higher than average levels of hyperactivity. The profile of Language and Social Skills strengths and weaknesses was similar to patterns observed in children with ADD/ADHD. Age of adoption was not predictive of school-age outcomes on these measures, but the children's expressive vocabulary when they were 2 to 3 years of age predicted SSRS outcomes for Social Skills and Problem Behaviors.

  12. Standards-based teaching and educational digital libraries as innovations: Undergraduate science faculty in the adoption process

    NASA Astrophysics Data System (ADS)

    Ridgway, Judith Sulkes

    This study describes undergraduate science faculty in terms of their feelings of preparedness for and their use of standards-based teaching methods, their stages of concern related to Educational Digital Libraries (EDLs), and their adoption and diffusion of both innovations. These innovations may have a synergistic relationship that may result in enhanced adoption of both. The investigation began with a series of group meetings with life science, chemistry, physics, and geology faculty from a 2-year and a 4-year institution. Faculty were introduced to dimensions of standards-based teaching and examples of EDLs. Faculty completed the Demographics and Experience Questionnaire, the Standards-Based Teaching Instrument, and the Stages of Concern Questionnaire (SoCQ). Semi-structured interviews containing literature-based questions were conducted with one faculty member from each discipline from the 2-year and 4-year institutions. Document analyses were performed on mission/goal web-based statements for the institutions and their science departments. Triangulated data were used to construct individual faculty case studies based on four facets: background, standards-based teaching profile, EDLs profile, and rate of innovation diffusion. The individual case studies were used to perform cross-case analyses by type of institution, discipline, and locus of control. Individual case studies and cross-case analyses suggest the following conclusions: (a) faculty felt prepared to use and frequently used textbooks as a reference, (b) feelings of preparedness and frequency of use of standards-based teaching categories may be related to discipline, (c) all faculty had relatively high awareness and informational EDL concerns, and (d) faculty central to the locus of control were more likely to use methods to develop student conceptual understanding, use inquiry methods, and be agents of change. A grounded theoretical model connects study results with literature related to educational

  13. The test technology of electrical safety performances based on IEC international standards

    NASA Astrophysics Data System (ADS)

    Wang, Xiaofei; Zhang, Zhaohui; Li, Dong; Wang, Yanlin

    2008-10-01

    The test technology of electrical safety performance based on IEC international standards is put forward in the paper, including mainly four test parameters: leakage current, high-voltage withstand, insulation resistance and ground resistance. The definitions, the types, the testing purposes and methods of these parameters are also proposed. Based on the technology, we construct a system for data collection, processing and controlling with a PC, a high-performance microcomputer ADμC842 and a FPGA, and adopts a VI technology to develop an integrated testing system for electrical safety performance. The system can be applied to both the certification testing of products and quality control in manufacturing and provides an authenticating measure for the domestic electrical equipments to enter international markets.

  14. International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics.

    PubMed

    Jutel, Marek; Agache, Ioana; Bonini, Sergio; Burks, A Wesley; Calderon, Moises; Canonica, Walter; Cox, Linda; Demoly, Pascal; Frew, Antony J; O'Hehir, Robyn; Kleine-Tebbe, Jörg; Muraro, Antonella; Lack, Gideon; Larenas, Désirée; Levin, Michael; Martin, Bryan L; Nelson, Harald; Pawankar, Ruby; Pfaar, Oliver; van Ree, Ronald; Sampson, Hugh; Sublett, James L; Sugita, Kazunari; Du Toit, George; Werfel, Thomas; Gerth van Wijk, Roy; Zhang, Luo; Akdis, Mübeccel; Akdis, Cezmi A

    2016-02-01

    This article continues the comprehensive international consensus (ICON) statement on allergen immunotherapy (AIT). The initial article also recently appeared in the Journal. The conclusions below focus on key mechanisms of AIT-triggered tolerance, requirements in allergen standardization, AIT cost-effectiveness, and regulatory guidance. Potential barriers to and facilitators of the use of AIT are described in addition to future directions. International allergy specialists representing the European Academy of Allergy and Clinical Immunology; the American Academy of Allergy, Asthma & Immunology; the American College of Allergy, Asthma and Immunology; and the World Allergy Organization critically reviewed the existing literature and prepared this summary of recommendations for best AIT practice. The authors contributed equally and reached consensus on the statements presented herein. PMID:26853128

  15. International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics.

    PubMed

    Jutel, Marek; Agache, Ioana; Bonini, Sergio; Burks, A Wesley; Calderon, Moises; Canonica, Walter; Cox, Linda; Demoly, Pascal; Frew, Antony J; O'Hehir, Robyn; Kleine-Tebbe, Jörg; Muraro, Antonella; Lack, Gideon; Larenas, Désirée; Levin, Michael; Martin, Bryan L; Nelson, Harald; Pawankar, Ruby; Pfaar, Oliver; van Ree, Ronald; Sampson, Hugh; Sublett, James L; Sugita, Kazunari; Du Toit, George; Werfel, Thomas; Gerth van Wijk, Roy; Zhang, Luo; Akdis, Mübeccel; Akdis, Cezmi A

    2016-02-01

    This article continues the comprehensive international consensus (ICON) statement on allergen immunotherapy (AIT). The initial article also recently appeared in the Journal. The conclusions below focus on key mechanisms of AIT-triggered tolerance, requirements in allergen standardization, AIT cost-effectiveness, and regulatory guidance. Potential barriers to and facilitators of the use of AIT are described in addition to future directions. International allergy specialists representing the European Academy of Allergy and Clinical Immunology; the American Academy of Allergy, Asthma & Immunology; the American College of Allergy, Asthma and Immunology; and the World Allergy Organization critically reviewed the existing literature and prepared this summary of recommendations for best AIT practice. The authors contributed equally and reached consensus on the statements presented herein.

  16. Developmental and Behavioral Performance of Internationally Adopted Preschoolers: A Pilot Study

    ERIC Educational Resources Information Center

    Jacobs, Emma; Miller, Laurie C.; Tirella, Linda G.

    2010-01-01

    Most international adoptees (IA) have rapid catch-up of the delays common at arrival. However, it is not known whether development at arrival predicts later abilities or school readiness. Therefore, we comprehensively evaluated language, fine motor, visual reception (VR), executive function (EF), attention (ATT), and sensory skills (SS) in IA…

  17. A New Pathway for Advanced Learning: A Bilingual School Adopts the Advanced International Certificate of Education.

    ERIC Educational Resources Information Center

    Garvie, Martin A.

    1998-01-01

    Describes the experiences of St. Hilda's College, a bilingual school in Buenos Aires, in introducing the new set of pre-university examinations offered by the University of Cambridge Local Examinations Syndicate to replace the outmoded "A" level examination scheme. The Advanced International Certificate of Education curriculum should interest…

  18. Integrated Procedures for Flight and Ground Operations Using International Standards

    NASA Technical Reports Server (NTRS)

    Ingalls, John

    2011-01-01

    Imagine astronauts using the same Interactive Electronic Technical Manuals (IETM's) as the ground personnel who assemble or maintain their flight hardware, and having all of that data interoperable with design, logistics, reliability analysis, and training. Modern international standards and their corresponding COTS tools already used in other industries provide a good foundation for streamlined technical publications in the space industry. These standards cover everything from data exchange to product breakdown structure to business rules flexibility. Full Product Lifecycle Support (PLCS) is supported. The concept is to organize, build once, reuse many ways, and integrate. This should apply to all future and some current launch vehicles, payloads, space stations/habitats, spacecraft, facilities, support equipment, and retrieval ships.

  19. The pluralization of the international: Resistance and alter-standardization in regenerative stem cell medicine

    PubMed Central

    Rosemann, Achim; Chaisinthop, Nattaka

    2016-01-01

    The article explores the formation of an international politics of resistance and ‘alter-standardization’ in regenerative stem cell medicine. The absence of internationally harmonized regulatory frameworks in the clinical stem cell field and the presence of lucrative business opportunities have resulted in the formation of transnational networks adopting alternative research standards and practices. These oppose, as a universal global standard, strict evidence-based medicine clinical research protocols as defined by scientists and regulatory agencies in highly developed countries. The emergence of transnational spaces of alter-standardization is closely linked to scientific advances in rapidly developing countries such as China and India, but calls for more flexible regulatory frameworks, and the legitimization of experimental for-profit applications outside of evidence-based medical care, are emerging increasingly also within more stringently regulated countries, such as the United States and countries in the European Union. We can observe, then, a trend toward the pluralization of the standards, practices, and concepts in the stem cell field. PMID:26983174

  20. The pluralization of the international: Resistance and alter-standardization in regenerative stem cell medicine.

    PubMed

    Rosemann, Achim; Chaisinthop, Nattaka

    2016-02-01

    The article explores the formation of an international politics of resistance and 'alterstandardization' in regenerative stem cell medicine. The absence of internationally harmonized regulatory frameworks in the clinical stem cell field and the presence of lucrative business opportunities have resulted in the formation of transnational networks adopting alternative research standards and practices. These oppose, as a universal global standard, strict evidence-based medicine clinical research protocols as defined by scientists and regulatory agencies in highly developed countries. The emergence of transnational spaces of alter-standardization is closely linked to scientific advances in rapidly developing countries such as China and India, but calls for more flexible regulatory frameworks, and the legitimization of experimental for-profit applications outside of evidence-based medical care, are emerging increasingly also within more stringently regulated countries, such as the United States and countries in the European Union. We can observe, then, a trend toward the pluralization of the standards, practices, and concepts in the stem cell field.

  1. A Meta-Analysis of Typhoid Diagnostic Accuracy Studies: A Recommendation to Adopt a Standardized Composite Reference.

    PubMed

    Storey, Helen L; Huang, Ying; Crudder, Chris; Golden, Allison; de los Santos, Tala; Hawkins, Kenneth

    2015-01-01

    Novel typhoid diagnostics currently under development have the potential to improve clinical care, surveillance, and the disease burden estimates that support vaccine introduction. Blood culture is most often used as the reference method to evaluate the accuracy of new typhoid tests; however, it is recognized to be an imperfect gold standard. If no single gold standard test exists, use of a composite reference standard (CRS) can improve estimation of diagnostic accuracy. Numerous studies have used a CRS to evaluate new typhoid diagnostics; however, there is no consensus on an appropriate CRS. In order to evaluate existing tests for use as a reference test or inclusion in a CRS, we performed a systematic review of the typhoid literature to include all index/reference test combinations observed. We described the landscape of comparisons performed, showed results of a meta-analysis on the accuracy of the more common combinations, and evaluated sources of variability based on study quality. This wide-ranging meta-analysis suggests that no single test has sufficiently good performance but some existing diagnostics may be useful as part of a CRS. Additionally, based on findings from the meta-analysis and a constructed numerical example demonstrating the use of CRS, we proposed necessary criteria and potential components of a typhoid CRS to guide future recommendations. Agreement and adoption by all investigators of a standardized CRS is requisite, and would improve comparison of new diagnostics across independent studies, leading to the identification of a better reference test and improved confidence in prevalence estimates.

  2. Neurocognitive and behavioral correlates of non-right-handedness in internationally adopted children.

    PubMed

    Larsen, Tory L; Helder, Emily J; Behen, Michael E

    2012-01-01

    The incidence of non-right-handedness was assessed among a sample of international adoptees. Neurocognitive and behavioral correlates to handedness were also examined among participants. A sample of 139 international adoptees (54 males; mean age at testing = 111.4 months ± 32.9 months) underwent a comprehensive neuropsychological evaluation, assessing verbal and visual reasoning, language, memory, attention, impulse control, processing speed, academic functioning, manual dexterity, and behavioral functioning. Over 26% of participants reported non-right-handedness. Non-right- and right-handers did not differ on demographic or orphanage specific variables. The groups were found to significantly differ on behavioral indices of attention and several neurocognitive variables, including visual memory, verbal memory, and manual dexterity of the dominant hand, with non-right-handers having worse performance. Possible mechanisms for these findings are discussed.

  3. Applying International Standards for Hydrokinetic Energy Resource Assessments

    NASA Astrophysics Data System (ADS)

    Haas, K. A.

    2015-12-01

    The extraction of hydrokinetic energy is the conversion of the kinetic energy of moving water into another more useful form of energy, frequently electricity. This water motion may be in the form of waves, tides, ocean currents or river flows. In addition to the development of the technology, the successful extraction of hydrokinetic energy requires a better understanding of physical, environmental and social aspects of the resource and their interactions with the technology. To assist with the development of the hydrokinetic industry as a whole, much work over the past decade has been completed developing international technical standards which can be used by the full range of stakeholders in the hydrokinetic industry. To support the design of projects for tidal energy extraction, a new International Electrotechnical Commission (IEC) Technical Specification (TS) has recently been published outlining a standardized methodology for performing resource assessments. In addition, presently work is ongoing on producing another TS for performing resource assessments on in-stream river projects. While the specific technology for extracting the energy from tidal and river flows may be similar, the methodologies for performing the respective resource assessments is quite different due to the differing nature of the physical processes involved. This presentation will discuss both the tidal and in-stream river methodologies, highlighting their respective key aspects. In addition, a case study illustrating the use of the published tidal TS will be presented.

  4. Brief International Cognitive Assessment for MS (BICAMS): international standards for validation

    PubMed Central

    2012-01-01

    An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary internationally, the committee identified validation priorities, to facilitate international acceptance of BICAMS. Practical matters pertaining to implementation across different languages and countries were discussed. Five steps to achieve optimal psychometric validation were proposed. In Step 1, test stimuli should be standardized for the target culture or language under consideration. In Step 2, examiner instructions must be standardized and translated, including all information from manuals necessary for administration and interpretation. In Step 3, samples of at least 65 healthy persons should be studied for normalization, matched to patients on demographics such as age, gender and education. The objective of Step 4 is test-retest reliability, which can be investigated in a small sample of MS and/or healthy volunteers over 1–3 weeks. Finally, in Step 5, criterion validity should be established by comparing MS and healthy controls. At this time, preliminary studies are underway in a number of countries as we move forward with this international assessment tool for cognition in MS. PMID:22799620

  5. Factors Influencing Adoption of the International Financial Reporting Standards (IFRS) in Accounting Education

    ERIC Educational Resources Information Center

    Alzeban, Abdulaziz

    2016-01-01

    Purpose: This paper aims to explore the challenges faced by accounting educators in their attempts to incorporate IFRS materials in their teaching and explores the impact of various factors (instructor's attitude, size of accounting department, teaching load, type of institution, teaching experience and teaching materials) on the time spent on…

  6. Occupational exposures worldwide and revision of international standards for protection.

    PubMed

    Czarwinski, R; Crick, M J

    2011-03-01

    United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) has become the world authority on the levels and effects of ionising radiation. Since 1975, UNSCEAR has evaluated inter alia the level of occupational exposure worldwide. Based on revised questionnaires, more detailed information is now available. The results of the last evaluation (1995-2002) will be shown in the paper. Lessons learned from the responses by UN Member States will be given, as well as an outline of plans for data collection in future cycles. The requirements for protection against exposure to ionising radiation of workers, the public and patients are established in the International Basic Safety Standards for Protection against Ionising Radiation and for the Safety of Radiation Sources (BSS), published in 1996. As a result of a review of the BSS in 2006, the International Atomic Energy Agency (IAEA) started a process for the revision of these standards in 2007. International organisations including the joint sponsoring organisations of the BSS-IAEA, FAO, ILO, OECD/NEA, PAHO and WHO--as well as potential new joint sponsoring organisations of the revised BSS--the European Commission and UNEP-were involved from the beginning in the revision process. The paper also provides a summary of the status of the Draft Revised BSS and describes the new format. The paper focuses, in particular, on requirements for the protection of workers as well as recordkeeping requirements, which provide the legal basis for the collection of specific data; these data are of the type that can be used by UNSCEAR. PMID:21148586

  7. International Standardization of the Clinical Dosimetry of Beta Radiation Brachytherapy Sources: Progress of an ISO Standard

    NASA Astrophysics Data System (ADS)

    Soares, Christopher

    2006-03-01

    In 2004 a new work item proposal (NWIP) was accepted by the International Organization for Standardization (ISO) Technical Committee 85 (TC85 -- Nuclear Energy), Subcommittee 2 (Radiation Protection) for the development of a standard for the clinical dosimetry of beta radiation sources used for brachytherapy. To develop this standard, a new Working Group (WG 22 - Ionizing Radiation Dosimetry and Protocols in Medical Applications) was formed. The standard is based on the work of an ad-hoc working group initiated by the Dosimetry task group of the Deutsches Insitiut für Normung (DIN). Initially the work was geared mainly towards the needs of intravascular brachytherapy, but with the decline of this application, more focus has been placed on the challenges of accurate dosimetry for the concave eye plaques used to treat ocular melanoma. Guidance is given for dosimetry formalisms, reference data to be used, calibrations, measurement methods, modeling, uncertainty determinations, treatment planning and reporting, and clinical quality control. The document is currently undergoing review by the ISO member bodies for acceptance as a Committee Draft (CD) with publication of the final standard expected by 2007. There are opportunities for other ISO standards for medical dosimetry within the framework of WG22.

  8. How did international agencies perceive the avian influenza problem? The adoption and manufacture of the 'One World, One Health' framework.

    PubMed

    Chien, Yu-Ju

    2013-02-01

    Over the past few years, a 'One World, One Health' (OWOH) policy framework has become the guiding principle for international responses to avian influenza and other zoonotic infectious diseases. Several specialised inter-governmental agencies, including the World Health Organization, the Food and Agricultural Organization and World Organization for Animal Health, jointly endorsed and promoted this framework. This article attempts to explain why international agencies advocated OWOH despite its vagueness. By examining how these international agencies gradually reframed avian flu problems, this article illustrates the crucial roles of international agencies in constructing disease knowledge and relevant policy responses. It shows that the three agencies adopted an all-inclusive approach to reduce conflicts, defend their legitimacy, and facilitate commitment for collaboration. Not only has this new framework reduced tensions between agencies, it has also reshaped the interests and interactions of other global actors. The case thus illustrates how these organisational actors actively manufacture new cognitive frames and policy regimes that advance their own legitimacy and influence. PMID:23095003

  9. International Micrographics Standards: Report of the 1979 Paris Meeting of ISO/TC171.

    ERIC Educational Resources Information Center

    Heynen, Jeffrey

    1980-01-01

    Describes a meeting of the technical committee on micrographics of the International Organization for Standardization, and fcuses on the committee's work relating to the reproduction of library materials within the general context of international standards-making activities. (FM)

  10. Barriers to the Adoption of Safety-Engineered Needles Following a Regulatory Standard: Lessons Learned from Three Acute Care Hospitals

    PubMed Central

    Chambers, Andrea; Mustard, Cameron A.; Holness, D. Linn; Nichol, Kathryn; Breslin, F. Curtis

    2015-01-01

    Background: A number of jurisdictions have introduced regulation to accelerate the adoption of safety-engineered needles (SENs). This study examined the transition to SENs in three acute care hospitals prior to and following the implementation of a regulatory standard in Ontario. This paper focuses on the ongoing barriers to the prevention of needlestick injuries among healthcare workers. Methods: Information from document review and 30 informant interviews were used to prepare three case studies detailing each organization's implementation activities and outcomes. Results: All three hospitals responded to the regulatory requirements with integrity and needlestick injuries declined. However, needlestick injuries continued to occur during the activation of safety devices, during procedures and during instrument disposal. The study documented substantial barriers to further progress in needlestick injury prevention. Conclusions: Healthcare organizations should focus on understanding their site-specific challenges that contribute to ongoing injury risk to better understand issues related to product limitations, practice constraints and the work environment. PMID:26571471

  11. International longitudinal pediatric reference standards for bone mineral content.

    PubMed

    Baxter-Jones, Adam D G; Burrows, Melonie; Bachrach, Laura K; Lloyd, Tom; Petit, Moira; Macdonald, Heather; Mirwald, Robert L; Bailey, Don; McKay, Heather

    2010-01-01

    To render a diagnosis pediatricians rely upon reference standards for bone mineral density or bone mineral content, which are based on cross-sectional data from a relatively small sample of children. These standards are unable to adequately represent growth in a diverse pediatric population. Thus, the goal of this study was to develop sex and site-specific standards for BMC using longitudinal data collected from four international sites in Canada and the United States. Data from four studies were combined; Saskatchewan Paediatric Bone Mineral Accrual Study (n=251), UBC Healthy Bones Study (n=382); Penn State Young Women's Health Study (n=112) and Stanford's Bone Mineral Accretion study (n=423). Males and females (8 to 25 years) were measured for whole body (WB), total proximal femur (PF), femoral neck (FN) and lumbar spine (LS) BMC (g). Data were analyzed using random effects models. Bland-Altman was used to investigate agreement between predicted and actual data. Age, height, weight and ethnicity independently predicted BMC accrual across sites (P<0.05). Compared to White males, Asian males had 31.8 (6.8) g less WB BMC accrual; Hispanic 75.4 (28.2) g less BMC accrual; Blacks 82.8 (26.3) g more BMC accrual with confounders of age, height and weight controlled. We report similar findings for the PF and FN. Models for females for all sites were similar with age, height and weight as independent significant predictors of BMC accrual (P<0.05). We provide a tool to calculate a child's BMC Z-score, accounting for age, size, sex and ethnicity. In conclusion, when interpreting BMC in pediatrics we recommend standards that are sex, age, size and ethnic specific. PMID:19854308

  12. Objectives And Structures Of The International Organization For Standardization (ISO)

    NASA Astrophysics Data System (ADS)

    Reihlen, Helmut

    1989-04-01

    I am certainly pleased to be with you here today, and to speak to you on the subject of international standardization. The work of some of the ISO technical committees, such as ISO/TC 36 "Cinematography", ISO/TC 42 "Photograhy" and, of course, ISO/TC 172 "Optics and optical instruments" may be familiar to many of you and their activities will be presented in your technical sessions. Rather than going into the detail of these technical committees it might be appropriate that, in my capacity as Vice-President of ISO, I present to you an overview of the organization, what it aims to do, with what means, what its achievements are and how it does its job in practice.

  13. A Meta-Analysis of Typhoid Diagnostic Accuracy Studies: A Recommendation to Adopt a Standardized Composite Reference

    PubMed Central

    Storey, Helen L.; Huang, Ying; Crudder, Chris; Golden, Allison; de los Santos, Tala; Hawkins, Kenneth

    2015-01-01

    Novel typhoid diagnostics currently under development have the potential to improve clinical care, surveillance, and the disease burden estimates that support vaccine introduction. Blood culture is most often used as the reference method to evaluate the accuracy of new typhoid tests; however, it is recognized to be an imperfect gold standard. If no single gold standard test exists, use of a composite reference standard (CRS) can improve estimation of diagnostic accuracy. Numerous studies have used a CRS to evaluate new typhoid diagnostics; however, there is no consensus on an appropriate CRS. In order to evaluate existing tests for use as a reference test or inclusion in a CRS, we performed a systematic review of the typhoid literature to include all index/reference test combinations observed. We described the landscape of comparisons performed, showed results of a meta-analysis on the accuracy of the more common combinations, and evaluated sources of variability based on study quality. This wide-ranging meta-analysis suggests that no single test has sufficiently good performance but some existing diagnostics may be useful as part of a CRS. Additionally, based on findings from the meta-analysis and a constructed numerical example demonstrating the use of CRS, we proposed necessary criteria and potential components of a typhoid CRS to guide future recommendations. Agreement and adoption by all investigators of a standardized CRS is requisite, and would improve comparison of new diagnostics across independent studies, leading to the identification of a better reference test and improved confidence in prevalence estimates. PMID:26566275

  14. A Meta-Analysis of Typhoid Diagnostic Accuracy Studies: A Recommendation to Adopt a Standardized Composite Reference.

    PubMed

    Storey, Helen L; Huang, Ying; Crudder, Chris; Golden, Allison; de los Santos, Tala; Hawkins, Kenneth

    2015-01-01

    Novel typhoid diagnostics currently under development have the potential to improve clinical care, surveillance, and the disease burden estimates that support vaccine introduction. Blood culture is most often used as the reference method to evaluate the accuracy of new typhoid tests; however, it is recognized to be an imperfect gold standard. If no single gold standard test exists, use of a composite reference standard (CRS) can improve estimation of diagnostic accuracy. Numerous studies have used a CRS to evaluate new typhoid diagnostics; however, there is no consensus on an appropriate CRS. In order to evaluate existing tests for use as a reference test or inclusion in a CRS, we performed a systematic review of the typhoid literature to include all index/reference test combinations observed. We described the landscape of comparisons performed, showed results of a meta-analysis on the accuracy of the more common combinations, and evaluated sources of variability based on study quality. This wide-ranging meta-analysis suggests that no single test has sufficiently good performance but some existing diagnostics may be useful as part of a CRS. Additionally, based on findings from the meta-analysis and a constructed numerical example demonstrating the use of CRS, we proposed necessary criteria and potential components of a typhoid CRS to guide future recommendations. Agreement and adoption by all investigators of a standardized CRS is requisite, and would improve comparison of new diagnostics across independent studies, leading to the identification of a better reference test and improved confidence in prevalence estimates. PMID:26566275

  15. 76 FR 37953 - Standards of Performance for Stationary Compression Ignition and Spark Ignition Internal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-28

    ... Performance for Stationary Compression Ignition and Spark Ignition Internal Combustion Engines; Final Rule #0... for Stationary Compression Ignition and Spark Ignition Internal Combustion Engines AGENCY: The... standards of performance for new stationary compression ignition internal combustion engines under...

  16. Using FTIR-ATR Spectroscopy to Teach the Internal Standard Method

    ERIC Educational Resources Information Center

    Bellamy, Michael K.

    2010-01-01

    The internal standard method is widely applied in quantitative analyses. However, most analytical chemistry textbooks either omit this topic or only provide examples of a single-point internal standardization. An experiment designed to teach students how to prepare an internal standard calibration curve is described. The experiment is a modified…

  17. Commutability of Cytomegalovirus WHO International Standard in Different Matrices

    PubMed Central

    Jones, Sara; Webb, Erika M.; Barry, Catherine P.; Choi, Won S.; Abravaya, Klara B.; Schneider, George J.

    2016-01-01

    Commutability of quantitative standards allows patient results to be compared across molecular diagnostic methods and laboratories. This is critical to establishing quantitative thresholds for use in clinical decision-making. A matrix effect associated with the 1st cytomegalovirus (CMV) WHO international standard (IS) was identified using the Abbott RealTime CMV assay. A commutability study was performed to compare the CMV WHO IS and patient specimens diluted in plasma and whole blood. Patient specimens showed similar CMV DNA quantitation values regardless of the diluent or extraction procedure used. The CMV WHO IS, on the other hand, exhibited a matrix effect. The CMV concentration reported for the WHO IS diluted in plasma was within the 95% prediction interval established with patient samples. In contrast, the reported DNA concentration of the CMV WHO IS diluted in whole blood was reduced approximately 0.4 log copies/ml, and values fell outside the 95% prediction interval. Calibrating the assay by using the CMV WHO IS diluted in whole blood would introduce a bias for CMV whole-blood quantitation; samples would be reported as having higher measured concentrations, by approximately 0.4 log IU/ml. Based on the commutability study with patient samples, the RealTime CMV assay was standardized based on the CMV WHO IS diluted in plasma. A revision of the instructions for use of the CMV WHO IS should be considered to alert users of the potential impact from the diluent matrix. The identification of a matrix effect with the CMV WHO IS underscores the importance of assessing commutability of the IS in order to achieve consistent results across methods. PMID:27030491

  18. Replacement of the International Standard for Tetanus Antitoxin and the Use of the Standard in the Flocculation Test

    PubMed Central

    Spaun, J.; Lyng, J.

    1970-01-01

    Since 1935 the International Unit for Tetanus Antitoxin has been defined as the activity contained in a certain weight of the first International Standard for Tetanus Antitoxin. As stocks of this standard had become depleted, 11 laboratories in 8 countries were requested to participate in a collaborative assay of a preparation proposed as a replacement. The assay results were analysed and presented to the WHO Expert Committee on Biological Standardization in 1969 which established the preparation studied as the second International Standard for Tetanus Antitoxin and defined the International Unit for Tetanus Antitoxin as the activity contained in 0.03384 mg of the second International Standard for Tetanus Antitoxin. This definition would ensure the continuity of the size of this international unit. The analysis of the collaborative studies also showed that the second International Standard for Tetanus Antitoxin has suitable properties for use in the flocculation test for the determination of the antigen content of tetanus toxoids in Lf values. The designation Lf-equivalent is described and the problems relating to the use of this term for the expression of results of in vitro assays are analysed in relation to the use of international units for expressing results of in vivo assays. As the second International Standard for Tetanus Antitoxin has an in vivo/in vitro ratio of 1.4, the Lf-equivalent of this antitoxin is 1.4 times less than its unitage. PMID:5310949

  19. 76 FR 12863 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... that provided national emission standards for hazardous air pollutants for existing stationary spark... Docket Center (6102T), National Emission Standards for Hazardous Air Pollutant for Stationary... Standards for Hazardous Air Pollutant for Stationary Reciprocating Internal Combustion Engines...

  20. Illinois Department of Children and Family Services Text of Adopted Rules. Subchapter e: Requirements for Licensure. Part 406: Licensing Standards for Day Care Homes.

    ERIC Educational Resources Information Center

    Illinois State Dept. of Children and Family Services, Springfield.

    Reprinted are licensing standards for day care homes adopted and codified, effective July 1983, by the Illinois Department of Children and Family Services and as amended, effective January and March 1985. Sections of the report concern the purpose, definitions of terms, effective date of standards, application for license, application for renewal…

  1. The Times They Are A-Changing: The Influence of Railroad Technology on the Adoption of Standard Time Zones in 1883.

    ERIC Educational Resources Information Center

    Allen, Nathaniel

    2000-01-01

    Presents the story of the role railroad technology had in the adoption of Standard Time Zones in 1883 and also considers the influence of astronomers at the time. Includes the map of the standard railway time used by W. F. Allen and an annotated bibliography with primary and secondary sources. (CMK)

  2. Evolution of Climate Science Modelling Language within international standards frameworks

    NASA Astrophysics Data System (ADS)

    Lowe, Dominic; Woolf, Andrew

    2010-05-01

    The Climate Science Modelling Language (CSML) was originally developed as part of the NERC Data Grid (NDG) project in the UK. It was one of the first Geography Markup Language (GML) application schemas describing complex feature types for the metocean domain. CSML feature types can be used to describe typical climate products such as model runs or atmospheric profiles. CSML has been successfully used within NDG to provide harmonised access to a number of different data sources. For example, meteorological observations held in heterogeneous databases by the British Atmospheric Data Centre (BADC) and Centre for Ecology and Hydrology (CEH) were served uniformly as CSML features via Web Feature Service. CSML has now been substantially revised to harmonise it with the latest developments in OGC and ISO conceptual modelling for geographic information. In particular, CSML is now aligned with the near-final ISO 19156 Observations & Measurements (O&M) standard. CSML combines the O&M concept of 'sampling features' together with an observation result based on the coverage model (ISO 19123). This general pattern is specialised for particular data types of interest, classified on the basis of sampling geometry and topology. In parallel work, the OGC Met Ocean Domain Working Group has established a conceptual modelling activity. This is a cross-organisational effort aimed at reaching consensus on a common core data model that could be re-used in a number of met-related application areas: operational meteorology, aviation meteorology, climate studies, and the research community. It is significant to note that this group has also identified sampling geometry and topology as a key classification axis for data types. Using the Model Driven Architecture (MDA) approach as adopted by INSPIRE we demonstrate how the CSML application schema is derived from a formal UML conceptual model based on the ISO TC211 framework. By employing MDA tools which map consistently between UML and GML we

  3. Affirming the Goal: Is College and Career Readiness an Internationally Competitive Standard? Executive Summary

    ERIC Educational Resources Information Center

    ACT, Inc., 2011

    2011-01-01

    ACT examined the international competitiveness of college and career ready standards in the policy research report, Affirming the Goal: Is College and Career Readiness an Internationally Competitive Standard? In this study, ACT performed a linking analysis to identify the PISA (Program for International Student Assessment) scores in reading and…

  4. 77 FR 60625 - Minimum Internal Control Standards for Class II Gaming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... National Indian Gaming Commission 25 CFR Parts 542 and 543 RIN 3141-AA-37 Minimum Internal Control... while tribes and operations transition to the new Class II Minimum Internal Control Standards that were... part 543, Minimum Internal Control Standards Class II Gaming, with comprehensive and updated...

  5. Potential Impact of Adopting Maximum Technologies as Minimum Efficiency Performance Standards in the U.S. Residential Sector

    SciTech Connect

    Letschert, Virginie; Desroches, Louis-Benoit; McNeil, Michael; Saheb, Yamina

    2010-05-03

    The US Department of Energy (US DOE) has placed lighting and appliance standards at a very high priority of the U.S. energy policy. However, the maximum energy savings and CO2 emissions reduction achievable via minimum efficiency performance standards (MEPS) has not yet been fully characterized. The Bottom Up Energy Analysis System (BUENAS), first developed in 2007, is a global, generic, and modular tool designed to provide policy makers with estimates of potential impacts resulting from MEPS for a variety of products, at the international and/or regional level. Using the BUENAS framework, we estimated potential national energy savings and CO2 emissions mitigation in the US residential sector that would result from the most aggressive policy foreseeable: standards effective in 2014 set at the current maximum technology (Max Tech) available on the market. This represents the most likely characterization of what can be maximally achieved through MEPS in the US. The authors rely on the latest Technical Support Documents and Analytical Tools published by the U.S. Department of Energy as a source to determine appliance stock turnover and projected efficiency scenarios of what would occur in the absence of policy. In our analysis, national impacts are determined for the following end uses: lighting, television, refrigerator-freezers, central air conditioning, room air conditioning, residential furnaces, and water heating. The analyzed end uses cover approximately 65percent of site energy consumption in the residential sector (50percent of the electricity consumption and 80percent of the natural gas and LPG consumption). This paper uses this BUENAS methodology to calculate that energy savings from Max Tech for the U.S. residential sector products covered in this paper will reach an 18percent reduction in electricity demand compared to the base case and 11percent in Natural Gas and LPG consumption by 2030 The methodology results in reductions in CO2 emissions of a similar

  6. Development Of International Data Standards For The COSMOS/PEER-LL Virtual Data Center

    NASA Astrophysics Data System (ADS)

    Swift, J. N.

    2005-12-01

    captured are presently working on this task. The international geotechnical data dictionary and schema development is a highly collaborative effort funded by a pooled fund study coordinated by state DOTs and FHWA. The technical development of the standards called DIGGS (Data Interchange for Geotechnical and Geoenvironmental Specialists) is lead by a team consisting of representatives from the University of Florida, Department of Civil Engineering (UF), AGS, Construction Industry Research and Information Association (CIRIA), UKHA, Ohio DOT, and COSMOS. The first draft of DIGGS is currently in preparation. A Geotechnical Management System Group (GMS group), composed of representatives from 13 State DOTs, FHWA, US EPA, USACOE, USGS and UKHA, oversees and approves the development of the standards. The ultimate goal of both COSMOS-PEER Lifelines Project 2L03 and the international GMS working group is to produce open and flexible, GML-compliant XML schema-based data structures and data dictionaries for review and approval by DOTs, other public agencies, and the international engineering and geoenvironmental community at large, leading to adoption of internationally accepted geotechnical and geophysical data transfer standards. Establishment of these standards is intended to significantly facilitate the accessibility and exchange of geotechnical information world wide.

  7. Finite element analyses for seismic shear wall international standard problem

    SciTech Connect

    Park, Y.J.; Hofmayer, C.H.

    1998-04-01

    Two identical reinforced concrete (RC) shear walls, which consist of web, flanges and massive top and bottom slabs, were tested up to ultimate failure under earthquake motions at the Nuclear Power Engineering Corporation`s (NUPEC) Tadotsu Engineering Laboratory, Japan. NUPEC provided the dynamic test results to the OECD (Organization for Economic Cooperation and Development), Nuclear Energy Agency (NEA) for use as an International Standard Problem (ISP). The shear walls were intended to be part of a typical reactor building. One of the major objectives of the Seismic Shear Wall ISP (SSWISP) was to evaluate various seismic analysis methods for concrete structures used for design and seismic margin assessment. It also offered a unique opportunity to assess the state-of-the-art in nonlinear dynamic analysis of reinforced concrete shear wall structures under severe earthquake loadings. As a participant of the SSWISP workshops, Brookhaven National Laboratory (BNL) performed finite element analyses under the sponsorship of the U.S. Nuclear Regulatory Commission (USNRC). Three types of analysis were performed, i.e., monotonic static (push-over), cyclic static and dynamic analyses. Additional monotonic static analyses were performed by two consultants, F. Vecchio of the University of Toronto (UT) and F. Filippou of the University of California at Berkeley (UCB). The analysis results by BNL and the consultants were presented during the second workshop in Yokohama, Japan in 1996. A total of 55 analyses were presented during the workshop by 30 participants from 11 different countries. The major findings on the presented analysis methods, as well as engineering insights regarding the applicability and reliability of the FEM codes are described in detail in this report. 16 refs., 60 figs., 16 tabs.

  8. The International Reference Ionosphere - Climatological Standard for the Ionosphere

    NASA Technical Reports Server (NTRS)

    Bilitza, Dieter

    2006-01-01

    The International Reference Ionosphere (IRI) a joint project of URSI and COSPAR is the defacto standard for a climatological specification of ionospheric parameters. IRI is based on a wide range of ground and space data and has been steadily improved since its inception in 1969 with the ever-increasing volume of ionospheric data and with better mathematical descriptions of the observed global and temporal variation patterns. The IRI model has been validated with a large amount of data including data from the most recent ionospheric satellites (KOMPSAT, ROCSAT and TIMED) and data from global network of ionosondes. Several IRI teams are working on specific aspects of the IRI modeling effort including an improved representation of the topside ionosphere with a seamless transition to the plasmasphere, a new effort to represent the global variation of F2 peak parameters using the Neural Network (NN) technique, and the inclusion of several additional parameters in IRI, e.g., spread-F probability and ionospheric variability. Annual IRI workshops are the forum for discussions of these efforts and for all science activities related to IRI as well as applications of the IRI model in engineering and education. In this paper I will present a status report about the IRI effort with special emphasis on the presentations and results from the most recent IRI Workshops (Paris, 2004; Tortosa, 2005) and on the most important ongoing IRI activities. I will discuss the latest version of the IRI model, IRI-2006, highlighting the most recent changes and additions. Finally, the talk will review some of the applications of the IRI model with special emphasis on the use for radiowave propagation studies and communication purposes.

  9. 78 FR 14457 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... Reciprocating Internal Combustion Engines; New Source Performance Standards for Stationary Internal Combustion Engines Correction In rule document 2013-01288, appearing on pages 6674-6724 in the issue of...

  10. The Impact of International Standardization on the Rules of Entry for Serials

    ERIC Educational Resources Information Center

    Cannan, Judith Proctor

    1975-01-01

    The major provisions of the International Serials Data System and International Standard Bibliographic Description for Serials are presented and related to present rules of entry for serials as detailed in the Anglo-American Cataloging Rules. (Author)

  11. Collaborative study for the establishment of the 2(nd) International Standard for Bleomycin Complex A2/B2.

    PubMed

    Jorajuria, S; Raphalen, C; Dujardin, V; Daas, A

    2015-01-01

    Organization (WHO) International Standard (IS) for bleomycin complex A2/B2. Eight laboratories from different countries participated. Potencies of the candidate material were estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 1(st) IS for bleomycin complex A2/B2 was used as a reference. Based on the results of the study, the 2(nd) IS for bleomycin complex A2/B2 was adopted at the meeting of the WHO Expert Committee for Biological Standardization (ECBS) in 2014 with an assigned potency of 12 500 International Units (IU) per vial. The 2(nd) IS for bleomycin complex A2/B2 is available from the European Directorate for the Quality of Medicines & HealthCare (EDQM).

  12. Health insurance reform; announcement of maintenance changes to electronic data transaction standards adopted under the Health Insurance Portability and Accountability Act of 1996. Notification.

    PubMed

    2010-10-13

    This document announces maintenance changes to some of the Health Insurance Portability and Accountability Act of 1996 standards made by the Designated Standard Maintenance Organizations. The maintenance changes are non-substantive changes to correct minor errors, such as typographical errors, or to provide clarifications of the standards adopted in our regulations entitled "Health Insurance Reform; Modifications to the Health Insurance Portability and Accountability Act (HIPAA) Electronic Transaction Standards," published in the Federal Register on January 16, 2009. This document also instructs interested persons on how to obtain the corrections. PMID:20941887

  13. CTEPP STANDARD OPERATING PROCEDURE FOR PREPARATION OF SURROGATE RECOVERY STANDARD AND INTERNAL STANDARD SOLUTIONS FOR POLAR TARGET ANALYTES (SOP-5.26)

    EPA Science Inventory

    This SOP describes the method used for preparing surrogate recovery standard and internal standard solutions for the analysis of polar target analytes. It also describes the method for preparing calibration standard solutions for polar analytes used for gas chromatography/mass sp...

  14. An International Survey of Electric Storage Tank Water Heater Efficiency and Standards

    SciTech Connect

    Johnson, Alissa; Lutz, James; McNeil, Michael A.; Covary, Theo

    2013-11-13

    Water heating is a main consumer of energy in households, especially in temperate and cold climates. In South Africa, where hot water is typically provided by electric resistance storage tank water heaters (geysers), water heating energy consumption exceeds cooking, refrigeration, and lighting to be the most consumptive single electric appliance in the home. A recent analysis for the Department of Trade and Industry (DTI) performed by the authors estimated that standing losses from electric geysers contributed over 1,000 kWh to the annual electricity bill for South African households that used them. In order to reduce this burden, the South African government is currently pursuing a programme of Energy Efficiency Standards and Labelling (EES&L) for electric appliances, including geysers. In addition, Eskom has a history of promoting heat pump water heaters (HPWH) through incentive programs, which can further reduce energy consumption. This paper provides a survey of international electric storage water heater test procedures and efficiency metrics which can serve as a reference for comparison with proposed geyser standards and ratings in South Africa. Additionally it provides a sample of efficiency technologies employed to improve the efficiency of electric storage water heaters, and outlines programs to promote adoption of improved efficiency. Finally, it surveys current programs used to promote HPWH and considers the potential for this technology to address peak demand more effectively than reduction of standby losses alone

  15. Analysis of Potential Benefits and Costs of Adopting ASHRAE Standard 90.1-1999 as a Commercial Building Energy Code in Illinois Jurisdictions

    SciTech Connect

    Belzer, David B.; Cort, Katherine A.; Winiarski, David W.; Richman, Eric E.; Friedrich, Michele

    2002-05-01

    ASHRAE Standard 90.1-1999 was developed in an effort to set minimum requirements for energy efficienty design and construction of new commercial buildings. This report assesses the benefits and costs of adopting this standard as the building energy code in Illinois. Energy and economic impacts are estimated using BLAST combined with a Life-Cycle Cost approach to assess corresponding economic costs and benefits.

  16. Analysis of Potential Benefits and Costs of Adopting ASHRAE Standard 90.1-2001 as the Commercial Building Energy Code in Tennessee

    SciTech Connect

    Cort, Katherine A.; Winiarski, David W.; Belzer, David B.; Richman, Eric E.

    2004-09-30

    ASHRAE Standard 90.1-2001 Energy Standard for Buildings except Low-Rise Residential Buildings (hereafter referred to as ASHRAE 90.1-2001 or 90.1-2001) was developed in an effort to set minimum requirements for the energy efficient design and construction of new commercial buildings. The State of Tennessee is considering adopting ASHRAE 90.1-2001 as its commercial building energy code. In an effort to evaluate whether or not this is an appropriate code for the state, the potential benefits and costs of adopting this standard are considered in this report. Both qualitative and quantitative benefits and costs are assessed. Energy and economic impacts are estimated using the Building Loads Analysis and System Thermodynamics (BLAST) simulations combined with a Life-Cycle Cost (LCC) approach to assess corresponding economic costs and benefits. Tennessee currently has ASHRAE Standard 90A-1980 as the statewide voluntary/recommended commercial energy standard; however, it is up to the local jurisdiction to adopt this code. Because 90A-1980 is the recommended standard, many of the requirements of ASHRAE 90A-1980 were used as a baseline for simulations.

  17. International comparisons of intensive care: informing outcomes and improving standards

    PubMed Central

    Prin, Meghan; Wunsch, Hannah

    2013-01-01

    Purpose of review Interest in international comparisons of critical illness is growing, but the utility of these studies is questionable. This review examines the challenges of international comparisons and highlights areas where international data provide information relevant to clinical practice and resource allocation. Recent findings International comparisons of ICU resources demonstrate that definitions of critical illness and Intensive Care Unit (ICU) beds vary due to differences in ability to provide organ support and variable staffing. Despite these limitations, recent international data provide key information to understand the pros and cons of different availability of ICU beds on patient flow and outcomes, and also highlight the need to ensure long-term follow-up due to heterogeneity in discharge practices for critically ill patients. With increasing emphasis on curbing costs of healthcare, systems that deliver lower cost care provide data on alternative options, such as regionalization, flexible allocation of beds, and bed rationing. Summary Differences in provision of critical care can be leveraged to inform decisions on allocation of ICU beds, improve interpretation of clinical outcomes, and assess ways to decrease costs of care. International definitions of key components of critical care are needed to facilitate research and ensure rigorous comparisons. PMID:22954664

  18. Internal Standards: A Source of Analytical Bias For Volatile Organic Analyte Determinations

    EPA Science Inventory

    The use of internal standards in the determination of volatile organic compounds as described in SW-846 Method 8260C introduces a potential for bias in results once the internal standards (ISTDs) are added to a sample for analysis. The bias is relative to the dissimilarity betw...

  19. INTERNATIONAL STANDARDS FOR RESEARCH INTEGRITY: AN IDEA WHOSE TIME HAS COME?

    PubMed Central

    Resnik, David B.

    2014-01-01

    A movement to promulgate international ethics standards covering areas of conduct other than research with human subjects has now begun to gain momentum. This commentary explains why it is important to develop international research integrity standards and some of the problems that must be overcome to bring them to fruition. PMID:20183162

  20. What States Should Know about International Standards in Science: Highlights from Achieve's Analysis

    ERIC Educational Resources Information Center

    Achieve, Inc., 2010

    2010-01-01

    Achieve, through support from the Noyce Foundation, examined ten sets of international standards with the intent of informing the development of both the conceptual framework and Next Generation Science Standards. Achieve selected countries based on their strong performance on international assessments and/or their economic, political, or cultural…

  1. The Role of Internal Standards and their Interaction with Soils Impact Accuracy of Volatile Organics Determinations

    EPA Science Inventory

    Both US Environmental Protection Agency (EPA) SW-846 Methods 8260C/5035 and 8261A include mixing soil with water and addition of internal standards prior to analyses but the equilibration of internal standards with the soil is not required. With increasing total organic carbon (...

  2. The International Standard for the Description of Archives: A Progress Report.

    ERIC Educational Resources Information Center

    Cook, Michael

    1992-01-01

    Describes progress in the efforts to develop an international standard for the description of archives (ISAD(G)) under the auspices of the International Council on Archives (ICA). Reconciling national standards from various countries is discussed; and provenance, access points, authority files, and a hierarchy of levels of arrangement are…

  3. An Analysis of the External Environmental and Internal Organizational Factors Associated with Adoption of the Electronic Health Record

    ERIC Educational Resources Information Center

    Kruse, Clemens Scott

    2013-01-01

    Despite a Presidential Order in 2004 that launched national incentives for the use of health information technology, specifically the Electronic Health Record (EHR), adoption of the EHR has been slow. This study attempts to quantify factors associated with adoption of the EHR and Computerized Provider Order Entry (CPOE) by combining multiple…

  4. On the Consideration of Adoption and Implementation of The Next Generation Science Standards in a Local-Control Context: Supporting the Epistemology of Science through Education Policy

    NASA Astrophysics Data System (ADS)

    Lazzaro, Christopher C.

    On the Consideration of Adoption and Implementation of The Next Generation Science Standards in a Local-Control Context: Supporting the Epistemology of Science through Education Policy. Christopher C Lazzaro. The primary purpose of this research is to understand how and why members at each of the three levels of the education system within a local-control state made the decisions they did in supporting or hindering the adoption and implementation of the Next Generation Science Standards. This research concentrates on three levels of the education system in a local-control state; 1) the state level, 2) the district level, and 3) the school/teacher level, while investigating the following questions: 1. To what extent, and in what ways, do members in each of the three levels of the state education system advocate for adoption and implementation of the Next Generation Science Standards? 2. Are the members in each of the three levels motivated or compelled to consider adoption and implementation of the Next Generation Science Standards, why or why not? 3. To what extent, and in what ways, do the members in each of the three levels take into account science epistemology in their overall consideration of adoption/implementation of the NGSS? The data drew from a series of interviews from a prior study, "Challenges of Implementing the Next Generation Science Standards in Local-Control States in the U.S." (Sevian, Foster, & Scheff, 2012). After these data were coded and analyzed around the three research questions, this phenomenographic research study identified four key findings: Key Finding 1 - As the District Coordinators are uniquely situated within the state education system to be able to see both the on-the-ground practical implications and the high-level policy pressures of adopting and implementing the NGSS, they reflect the deepest level of awareness of how to best advocate for adoption and implementation of the NGSS. Key Finding 2 - Motivation to adopt and

  5. Improving the efficiency of quantitative (1)H NMR: an innovative external standard-internal reference approach.

    PubMed

    Huang, Yande; Su, Bao-Ning; Ye, Qingmei; Palaniswamy, Venkatapuram A; Bolgar, Mark S; Raglione, Thomas V

    2014-01-01

    The classical internal standard quantitative NMR (qNMR) method determines the purity of an analyte by the determination of a solution containing the analyte and a standard. Therefore, the standard must meet the requirements of chemical compatibility and lack of resonance interference with the analyte as well as a known purity. The identification of such a standard can be time consuming and must be repeated for each analyte. In contrast, the external standard qNMR method utilizes a standard with a known purity to calibrate the NMR instrument. The external standard and the analyte are measured separately, thereby eliminating the matter of chemical compatibility and resonance interference between the standard and the analyte. However, the instrumental factors, including the quality of NMR tubes, must be kept the same. Any deviations will compromise the accuracy of the results. An innovative qNMR method reported herein utilizes an internal reference substance along with an external standard to assume the role of the standard used in the traditional internal standard qNMR method. In this new method, the internal reference substance must only be chemically compatible and be free of resonance-interference with the analyte or external standard whereas the external standard must only be of a known purity. The exact purity or concentration of the internal reference substance is not required as long as the same quantity is added to the external standard and the analyte. The new method reduces the burden of searching for an appropriate standard for each analyte significantly. Therefore the efficiency of the qNMR purity assay increases while the precision of the internal standard method is retained. PMID:24013124

  6. Analysis of Potential Benefits and Costs of Adopting ASHRAE Standard 90.1-1999 as a Commercial Building Energy Code in Michigan

    SciTech Connect

    Cort, Katherine A.; Belzer, David B.; Halverson, Mark A.; Richman, Eric E.; Winiarski, David W.

    2002-09-30

    The state of Michigan is considering adpoting ASHRAE 90.1-1999 as its commercial building energy code. In an effort to evaluate whether or not this is an appropraite code for the state, the potential benefits and costs of adopting this standard are considered. Both qualitative and quantitative benefits are assessed. The energy simulation and economic results suggest that adopting ASHRAE 90.1-1999 would provide postitive net benefits to the state relative to the building and design requirements currently in place.

  7. 75 FR 19671 - International Standards on the Transport of Dangerous Goods; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... of International Standards Strategic Plan can be accessed at: http://www.phmsa.dot.gov/hazmat/regs...://www.phmsa.dot.gov/hazmat/regs/international . Documents Copies of documents for the UNSCOE TDG meeting....phmsa.dot.gov/hazmat/regs/international also provides additional information regarding the UNSCOE...

  8. 76 FR 25774 - International Standards on the Transport of Dangerous Goods; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... posted when available at http://www.phmsa.dot.gov/hazmat/regs/international . FOR FURTHER INFORMATION... of International Standards Strategic Plan can be accessed at: http://www.phmsa.dot.gov/hazmat/regs....dot.gov/hazmat/regs/international . PHMSA's site at...

  9. 75 FR 55269 - Minimum Internal Control Standards for Class II Gaming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... National Indian Gaming Commission 25 CFR Parts 542 and 543 RIN 3141-AA-37 Minimum Internal Control... the extension of the effective date on the final rule for Minimum Internal Control Standards for Class... internal controls found in Sec. 543.3(c)(3) to October 13, 2011, in order to extend the transition...

  10. 7 CFR 300.5 - International Standards for Phytosanitary Measures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... by the International Plant Protection Convention of the United Nations' Food and Agriculture Organization has been approved for incorporation by reference in 7 CFR chapter III by the Director of the Office of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. (b)...

  11. 7 CFR 300.5 - International Standards for Phytosanitary Measures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... by the International Plant Protection Convention of the United Nations' Food and Agriculture Organization has been approved for incorporation by reference in 7 CFR chapter III by the Director of the Office of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. (b)...

  12. Disentangling the effects of cognitive development and linguistic expertise: a longitudinal study of the acquisition of English in internationally-adopted children.

    PubMed

    Snedeker, Jesse; Geren, Joy; Shafto, Carissa L

    2012-08-01

    Early language development is characterized by predictable changes in the words children produce and the complexity of their utterances. In infants, these changes could reflect increasing linguistic expertise or cognitive maturation and development. To disentangle these factors, we compared the acquisition of English in internationally-adopted preschoolers and internationally-adopted infants. Parental reports and speech samples were collected for 1 year. Both groups showed the qualitative shifts that characterize first-language acquisition. Initially, they produced single-word utterances consisting mostly of nouns and social words. The appearance of verbs, adjectives and multiword utterances was predicted by vocabulary size in both groups. Preschoolers did learn some words at an earlier stage than infants, specifically words referring to the past or future and adjectives describing behavior and internal states. These findings suggest that cognitive development plays little role in the shift from referential terms to predicates but may constrain children's ability to learn some abstract words.

  13. Anthropometry and Standards for Wheeled Mobility: An International Comparison

    ERIC Educational Resources Information Center

    Steinfeld, Edward; Maisel, Jordana; Feathers, David; D'Souza, Clive

    2010-01-01

    Space requirements for accommodating wheeled mobility devices and their users in the built environment are key components of standards for accessible design. These requirements typically include dimensions for clear floor areas, maneuvering clearances, seat and knee clearance heights, as well as some reference dimensions on wheeled mobility device…

  14. New International Reference Standards of Voltage and Resistance.

    ERIC Educational Resources Information Center

    Sirvastava, V. P.

    1991-01-01

    The introduction of the quantum standards of resistance and voltage, based on the Quantum Hall Effect (QHE) and the Josephson Effect, can be used to establish highly reproducible and uniform representations of the ohm and volt worldwide. Discussed are the QHE and the Josephson Effect. (KR)

  15. Teacher Assessment Literacy: A Review of International Standards and Measures

    ERIC Educational Resources Information Center

    DeLuca, Christopher; LaPointe-McEwan, Danielle; Luhanga, Ulemu

    2016-01-01

    Assessment literacy is a core professional requirement across educational systems. Hence, measuring and supporting teachers' assessment literacy have been a primary focus over the past two decades. At present, there are a multitude of assessment standards across the world and numerous assessment literacy measures that represent different…

  16. Status of China's Energy Efficiency Standards and Labels for Appliances and International Collaboration

    SciTech Connect

    Zhou, Nan

    2008-03-01

    China first adopted minimum energy performance standards (MEPS) in 1989. Today, there are standards for a wide range of domestic, commercial and selected industrial equipment. In 1999, China launched a voluntary endorsement label, which has grown to cover over 40 products including water-saving products (See Figure 1). Further, in 2005, China started a mandatory energy information label (also referred to as the 'Energy Label'). Today, the Energy Label is applied to four products including: air conditioners; household refrigerators; clothes washers; and unitary air conditioners (See Figure 2). MEPS and the voluntary endorsement labeling specifications have been updated and revised in order to reflect technology improvements to those products in the market. These programs have had an important impact in reducing energy consumption of appliances in China. Indeed, China has built up a strong infrastructure to develop and implement product standards. Historically, however, the government's primary focus has been on the technical requirements for efficiency performance. Less attention has been paid to monitoring and enforcement with a minimal commitment of resources and little expansion of administrative capacity in this area. Thus, market compliance with both mandatory standards and labeling programs has been questionable and actual energy savings may have been undermined as a result. The establishment of a regularized monitoring system for tracking compliance with the mandatory standard and energy information label in China is a major area for program improvement. Over the years, the Collaborative Labeling and Appliance Standards Program (CLASP) has partnered with several Chinese institutions to promote energy-efficient products in China. CLASP, together with its implementing partner Lawrence Berkeley National Laboratory (LBNL), has assisted China in developing and updating the above-mentioned standards and labeling programs. Because of the increasing need for the

  17. Standards of radium-226: from Marie Curie to the International Committee for Radionuclide Metrology.

    PubMed

    Coursey, B M; Collé, R; Coursey, J S

    2002-01-01

    In the early part of the 20th century, the pioneers of radioactivity research, led by Marie Curie, Ernest Rutherford and Stefan Meyer, formed a Commission internationale des étalons de radium. The Commission made arrangements for the preparation and intercomparisons of the international standards of radium, which were identified as the Paris standard and the Vienna standard. Otto Hönigschmid from Vienna prepared a first set of international secondary standards in 1912 and a second set in 1934. In both instances, these secondary standards were compared by gamma-ray measurements with the Paris and Vienna standards. The usage of these international standards of radium in the 20th century is described.

  18. Directory of International and Regional Organizations Conducting Standards-Related Activities, May 1989

    NASA Astrophysics Data System (ADS)

    Breitenberg, Maureen

    1989-05-01

    The directory contains information on 338 international and regional organizations which conduct standardization, certification, laboratory accreditation, or other standards-related activities. The volume describes their work in these areas, the scope of each organization, national affliations of members, U.S. participants, restrictions on membership, as well as the availability of any standards in English. The volume is designed to serve the needs of Federal agencies and standards writers for information on international and regional organizations involved in standardization and related activities. It may also be useful to manufacturers, engineers, purchasing agents, and others.

  19. The Birth of a Standard.

    ERIC Educational Resources Information Center

    Adler, Sharon

    1992-01-01

    Discusses the Standard Generalized Markup Language (SGML), which was adopted as an international standard for data description, data modeling, and interchange in October 1986, and explores its evolution from its technical completion to its adoption by the international market. (four references) (LAE)

  20. Standard Setting to an International Reference Framework: Implications for Theory and Practice

    ERIC Educational Resources Information Center

    Lim, Gad S.; Geranpayeh, Ardeshir; Khalifa, Hanan; Buckendahl, Chad W.

    2013-01-01

    Standard setting theory has largely developed with reference to a typical situation, determining a level or levels of performance for one exam for one context. However, standard setting is now being used with international reference frameworks, where some parameters and assumptions of classical standard setting do not hold. We consider the…

  1. International regulations and standards for avian influenza, including the vaccine standards of the World Organisation for Animal Health.

    PubMed

    Bruschke, C J M; Pittman, M; Laddomada, A

    2009-04-01

    For avian influenza the World Organisation for Animal Health (OIE) has laid down international standards on notification, trade, diagnosis, surveillance and the production and use of vaccine. These standards are science- and risk-based to ensure safe trade in poultry and poultry products without unjustified barriers. The European Union, with its 27 Member States, has in place harmonised legislation in line with OIE standards. Early detection, rapid diagnosis, notification and high quality Veterinary Services are crucial for ensuring a rapid response to avian influenza outbreaks and for swiftly reducing the risk of virus spread via trade. Depending on the situation, vaccination may also be a very important tool for disease control. The use of high quality vaccines and postvaccination monitoring are essential for the successful implementation of vaccination. Compliance with international standards is of paramount importance for protecting animal and human health in the global crisis of the highly pathogenic avian influenza of the H5N1 subtype.

  2. FDA use of international standards in the premarket review process.

    PubMed

    Rechen, E; Barth, D J; Marlowe, D; Kroger, L

    1998-01-01

    "This is an exciting time," says Eric Rechen, policy analyst in the U.S. Food and Drug Administration's (FDA) Office of Device Evaluation (ODE). "We're entering an era in which standards will have a more prominent role in the review of medical devices than ever before." During the past 10 years, there has been significant growth in the importance of standards in regulatory processes, as Donald J. Barth, regulatory staff manager for the Medical Products Group at Hewlett Packard Company, notes in setting the stage for discussion of the latest developments. Donald Marlowe, director of the FDA's Office of Science and Technology, and Rechen explain the use of standards in the regulatory review process as part of FDA efforts to ensure public safety in a time of shrinking agency resources. Marlowe discusses provisions of the FDA Modernization Act of 1997 that allow manufacturers to submit a declaration of conformity to a standard to satisfy premarket review requirements. A guidance on the recognition and use of consensus standards, a list of recognized standards, and a list of frequently asked questions are available at the Web site of the Center for Devices and Radiological Health (CDRH) at www.fda.gov/cdrh and via the AAMI Web site at www.aami.org. The information is also available by telephone via CDRH Facts on Demand at 800-899-0381. Rechen provides details about the two new approaches for premarket notifications available under the new 510(k) paradigm. Manufacturers may demonstrate substantial equivalence through special and abbreviated 510(k)s in addition to traditional 510(k)s. A copy of the new 510(k) paradigm is available at the AAMI and CDRH Web sites and through Facts on Demand. As the FDA and many manufacturers enter the new world of abbreviated and special 510(k)s, Larry Kroger, GE Medical Systems, provides his comments based on the 4 years of experience manufacturers of diagnostic x-ray products have had with simplified 510(k)s. A comparison of the European

  3. Council on Accreditation of Nurse Anesthesia Educational Programs adopts standards for the Practice Doctorate and Post-graduate CRNA Fellowships.

    PubMed

    Gombkoto, Rebecca L Madsen; Walker, James R; Horton, Betty J; Martin-Sheridan, Denise; Yablonky, Mary Jean; Gerbasi, Francis R

    2014-06-01

    The Council on Accreditation of Nurse Anesthesia Educational Programs appointed a Standards Revision Task Force to develop new accreditation standards. After 3 years of research and development (2011-2013) by the task force, the Council approved the first entry-level Practice Doctorate Standards and the first voluntary Post-graduate CRNA Fellowship Standards in January 2014. This defining moment in accreditation history marks a transition in the educational preparation of entry-level nurse anesthetists and provides opportunities for learning in a variety of post-graduate fellowships for Certified Registered Nurse Anesthetists.

  4. PV Standards Work: Photovoltaic System and Component Certification, Test Facility Accreditation, and Solar Photovoltaic Energy Systems International Standards

    SciTech Connect

    Basso, T. S.; Chalmers, S.; Barikmo, H. O.

    2005-11-01

    This paper discusses efforts led by two companies (PowerMark Corporation and Sunset Technologies Inc.) to support both U.S. domestic and international photovoltaic (PV) system and component certification and test facility accreditation programs and the operation of the International Electrotechnical Commission (IEC) Technical Committee 82 (TC-82) Photovoltaic Energy Systems. International and national PV certification/accreditation programs are successfully facilitating entry of only the highest quality PV products into the marketplace. Standards also continue to be a cornerstone for assuring global PV product conformity assessment, reducing non-tariff trade barriers, and ultimately improving PV products while lowering cost.

  5. 49 CFR 1200.2 - Adoption of generally accepted accounting principles issued by the Financial Accounting Standards...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Financial Accounting Standards by the FASB, and provided that the Office of Economics, Environmental... regulations, the Office of Economics, Environmental Analysis, and Administration shall issue an Accounting... the Uniform Systems of Accounts, (49 CFR 1201 through 1210). (d) Accounting Standards Not...

  6. 49 CFR 1200.2 - Adoption of generally accepted accounting principles issued by the Financial Accounting Standards...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Financial Accounting Standards by the FASB, and provided that the Office of Economics, Environmental... regulations, the Office of Economics, Environmental Analysis, and Administration shall issue an Accounting... the Uniform Systems of Accounts, (49 CFR 1201 through 1210). (d) Accounting Standards Not...

  7. 49 CFR 1200.2 - Adoption of generally accepted accounting principles issued by the Financial Accounting Standards...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Financial Accounting Standards by the FASB, and provided that the Office of Economics, Environmental... regulations, the Office of Economics, Environmental Analysis, and Administration shall issue an Accounting... the Uniform Systems of Accounts, (49 CFR 1201 through 1210). (d) Accounting Standards Not...

  8. 49 CFR 1200.2 - Adoption of generally accepted accounting principles issued by the Financial Accounting Standards...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Financial Accounting Standards by the FASB, and provided that the Office of Economics, Environmental... regulations, the Office of Economics, Environmental Analysis, and Administration shall issue an Accounting... the Uniform Systems of Accounts, (49 CFR 1201 through 1210). (d) Accounting Standards Not...

  9. 49 CFR 1200.2 - Adoption of generally accepted accounting principles issued by the Financial Accounting Standards...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Financial Accounting Standards by the FASB, and provided that the Office of Economics, Environmental... regulations, the Office of Economics, Environmental Analysis, and Administration shall issue an Accounting... the Uniform Systems of Accounts, (49 CFR 1201 through 1210). (d) Accounting Standards Not...

  10. Evolving minimum standards in responsible international sperm donor offspring quota.

    PubMed

    Janssens, Pim M W; Thorn, Petra; Castilla, Jose A; Frith, Lucy; Crawshaw, Marilyn; Mochtar, Monique; Bjorndahl, Lars; Kvist, Ulrik; Kirkman-Brown, Jackson C

    2015-06-01

    An international working group was established with the aim of making recommendations on the number of offspring for a sperm donor that should be allowable in cases of international use of his sperm. Considerations from genetic, psychosocial, operational and ethical points of view were debated. For these considerations, it was assumed that current developments in genetic testing and Internet possibilities mean that, now, all donors are potentially identifiable by their offspring, so no distinction was made between anonymous and non-anonymous donation. Genetic considerations did not lead to restrictive limits (indicating that up to 200 offspring or more per donor may be acceptable except in isolated social-minority situations). Psychosocial considerations on the other hand led to proposals of rather restrictive limits (10 families per donor or less). Operational and ethical considerations did not lead to more or less concrete limits per donor, but seemed to lie in-between those resulting from the aforementioned ways of viewing the issue. In the end, no unifying agreed figure could be reached; however the consensus was that the number should never exceed 100 families. The conclusions of the group are summarized in three recommendations. PMID:25817048

  11. Archival-grade optical disc design and international standards

    NASA Astrophysics Data System (ADS)

    Fujii, Toru; Kojyo, Shinichi; Endo, Akihisa; Kodaira, Takuo; Mori, Fumi; Shimizu, Atsuo

    2015-09-01

    Optical discs currently on the market exhibit large variations in life span among discs, making them unsuitable for certain business applications. To assess and potentially mitigate this problem, we performed accelerated degradation testing under standard ISO conditions, determined the probable disc failure mechanisms, and identified the essential criteria necessary for a stable disc composition. With these criteria as necessary conditions, we analyzed the physical and chemical changes that occur in the disc components, on the basis of which we determined technological measures to reduce these degradation processes. By applying these measures to disc fabrication, we were able to develop highly stable optical discs.

  12. Survey and qualification of internal standards for quantification by 1H NMR spectroscopy.

    PubMed

    Rundlöf, Torgny; Mathiasson, Marie; Bekiroglu, Somer; Hakkarainen, Birgit; Bowden, Tim; Arvidsson, Torbjörn

    2010-09-01

    In quantitative NMR (qNMR) selection of an appropriate internal standard proves to be crucial. In this study, 25 candidate compounds considered to be potent internal standards were investigated with respect to the ability of providing unique signal chemical shifts, purity, solubility, and ease of use. The (1)H chemical shift (delta) values, assignments, multiplicities and number of protons (for each signal), appropriateness (as to be used as internal standards) in four different deuterated solvents (D(2)O, DMSO-d(6), CD(3)OD, CDCl(3)) were studied. Taking into account the properties of these 25 internal standards, the most versatile eight compounds (2,4,6-triiodophenol, 1,3,5-trichloro-2-nitrobenzene, 3,4,5-trichloropyridine, dimethyl terephthalate, 1,4-dinitrobenzene, 2,3,5-triiodobenzoic acid, maleic acid and fumaric acid) were qualified using both differential scanning calorimetry (DSC) and NMR spectroscopy employing highly pure acetanilide as the reference standard. The data from these two methods were compared as well as utilized in the quality assessment of the compounds as internal standards. Finally, the selected internal standards were tested and evaluated in a real case of quantitative NMR analysis of a paracetamol pharmaceutical product. PMID:20207092

  13. ISO 639-1 and ISO 639-2: International Standards for Language Codes. ISO 15924: International Standard for Names of Scripts.

    ERIC Educational Resources Information Center

    Byrum, John D.

    This paper describes two international standards for the representation of the names of languages. The first (ISO 639-1), published in 1988, provides two-letter codes for 136 languages and was produced primarily to meet terminological needs. The second (ISO 639-2) appeared in late 1998 and includes three-letter codes for 460 languages. This list…

  14. 25 CFR 543.23 - What are the minimum internal control standards for audit and accounting?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... audit report required pursuant to 25 CFR part 571. (3) Review of internal audit. (i) The CPA must... GAAP, GAAS, and standards promulgated by GASB and FASB. In the event of a conflict between the MICS...

  15. 25 CFR 543.23 - What are the minimum internal control standards for audit and accounting?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... audit report required pursuant to 25 CFR part 571. (3) Review of internal audit. (i) The CPA must... GAAP, GAAS, and standards promulgated by GASB and FASB. In the event of a conflict between the MICS...

  16. Technological Adoption and Organizational Adaptation: Developing a Model for Human Resource Management in an International Business Environment.

    ERIC Educational Resources Information Center

    Gattiker, Urs E.

    A model of technological training has two dimensions: level of cultural stability and employee's level of cognitive ability. Each dimension has two variables. The variables of cultural stability are (1) technological adoption and organizational adaptation and (2) structure of work and work processes. For cognitive ability, the variables are…

  17. [From manual workshop to international standard maker: exploration on production standard of acupuncture needle by Chengjiang acupuncture school].

    PubMed

    Cheng, Jie; Cao, Yang; Xia, Youbing

    2015-02-01

    ABSTRACT The exploration course on production standard of acupuncture needle by Chengjiang acupuncture school is reviewed in this paper. After new China was established, acupuncture needle standard was unified by Mr. CHENG Dan-an, which guided Suzhou Hua Erfang (predecessor of Suzhou Medical Supplies Factory) to make the quality standards and testing methods of acupuncture needle and improved the production process to make the modern acupuncture needle. Based on this, Suzhou Medical Supplies Factory followed the time development pace, ac tively introduced new technology, carried out technological innovation, and constantly improved the level of production technology, as a result, it gradually developed into one of the world's largest acupuncture needle production suppliers. Meanwhile, after establishing China's first national standard on acupuncture needle (GB 2024-1980), the Suzhou Medical Supplies Factory took the lead to draft "ISO) 17218:2014 the disposable use asepsis acupuncture needle", which was officially published as an international standard. The Suzhou Medical Supplies Factory developed from a manual workshop to an international standard maker.

  18. 25 CFR 542.16 - What are the minimum internal control standards for information technology?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... information technology? 542.16 Section 542.16 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.16 What are the minimum internal control.... (2) (f) Document storage. (1) Documents may be scanned or directly stored to an unalterable...

  19. International Labour Standards and Technical Co-Operation: The Case of Special Public Works Programmes.

    ERIC Educational Resources Information Center

    Mayer, Jean

    1989-01-01

    Applies international labor standards to results of the International Labour Office's special public works programs to discover whether program intentions have been met. Finds that while productive employment has been pursued, popular participation is not occurring and such issues as (1) forced labor, (2) child employment, and (3) inequality of…

  20. 49 CFR 171.22 - Authorization and conditions for the use of international standards and regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and the transportation in commerce of hazardous materials in accordance with the International Civil... international transport standards and regulations authorized in paragraph (a) of this section (e.g., paragraph 1... transported in the United States in full compliance (i.e., packaged, marked, labeled, classed,...

  1. International Standards Development for Marine and Hydrokinetic Renewable Energy - Final Report on Technical Status

    SciTech Connect

    Rondorf, Neil E.; Busch, Jason; Kimball, Richard

    2011-10-29

    This report summarizes the progress toward development of International Standards for Marine and Hydrokinetic Renewable Energy, as funded by the U.S. Department of Energy (DOE) under the International Electrotechnical Commission (IEC) Technical Committee 114. The project has three main objectives: 1. Provide funding to support participation of key U.S. industry technical experts in 6 (originally 4) international working groups and/or project teams (the primary standards-making committees) and to attend technical meetings to ensure greater U.S. involvement in the development of these standards. 2. Provide a report to DOE and industry stakeholders summarizing the IEC standards development process for marine and hydrokinetic renewable energy, new international standards and their justifications, and provide standards guidance to industry members. 3. Provide a semi-annual (web-based) newsletter to the marine renewable energy community. The newsletter will educate industry members and stakeholders about the processes, progress, and needs of the US efforts to support the international standards development effort. The newsletter is available at www.TC114.us

  2. The Role of District Office Leaders in the Adoption and Implementation of the Common Core State Standards in Elementary Schools

    ERIC Educational Resources Information Center

    Durand, Francesca T.; Lawson, Hal A.; Wilcox, Kristen Campbell; Schiller, Kathryn S.

    2016-01-01

    Purpose: This multiple case study investigated district leaders' orientations and strategies as their elementary schools proceeded with state-mandated implementation of the Common Core State Standards (CCSS). We identified differences between schools achieving above-predicted outcomes on state CCSS assessments ("odds-beaters") and…

  3. Evidence Related to Awareness, Adoption, and Implementation of the Standards for Technological Literacy: Content for the Study of Technology

    ERIC Educational Resources Information Center

    Russell, Jill F.

    2005-01-01

    Over the past twenty years American education has seen many changes, and most notable have been those related to accountability and assessment. One aspect of these changes has been the movement toward more specified student learning outcomes. In discipline after discipline content standards have been developed outlining that which students should…

  4. Commercial versus Internally Developed Standardized Tests: Lessons from a Small Regional School

    ERIC Educational Resources Information Center

    Hadjicharalambous, Costas

    2014-01-01

    The author compares the efficacy of commercially available and internally developed standardized tests and evaluates their strengths and weakness in assessing student learning outcomes. The author shares the experience of a regional school in developing a standardized test to assess business knowledge. Data from a sample of 268 students were used…

  5. Current Status of International Airborne Platform Data and Instrument Interface Standards

    NASA Astrophysics Data System (ADS)

    Freer, Matt; Webster, Chris; Freundinger, Larry

    2016-06-01

    Commission I of the International Society for Photogrammetric and Remote Sensing formed working group I/1 for the purpose of standardizing airborne platform interfaces. The primary mission of this working group is to promote the standardization of instrument interfaces, data formats, and supporting infrastructures; and to facilitate more efficient, flexible, and cost-effective international science flight operations. Within WGI/1 are a number of focused subgroups. This paper addresses the efforts of some of these subgroups having interdependent and overlapping interests; including the development of standard software interfaces for sensors, standardized approaches to management of information over potentially intermittent wireless data links, the development of standardized processing algorithms, and data archival format standards. The data in this report reflect the outcome of work-to-date in the current subgroups.

  6. Organizational leadership: A study on the affects of certification to International Organization for Standardization (ISO)

    NASA Astrophysics Data System (ADS)

    Cowart, Jewel S.

    Compliance to requirements of ISO is an important leadership problem for the International Aerospace Quality Group (IAQG) and the Aviation, Space and Defense (AS&D) companies. Furthermore, the IAQG seeks to understand the valuation of ISO/AS9100 requirements (2009), audit practices, management functions, business performance, customer satisfaction, and potential future concepts for the standard to assure quality. Since the release of the AS9100C total certification growth surpassed 1,100,000 organizations in 2010 with ISO 9001 series adoption and implementation governing business operations (ASQ, 2012b; ISO, 2011; Bernardo, Llach, & Marimon, 2011). Historians such as Crosby, Juran, Deming, and others established the foundation for quality assurance. Several researchers explored the issues which complicate overall benefits of ISO certification (Iwaro & Mwasha, 2012; Karthi et al., 2012; Sampaio et al., 2009). This study examined the effects on AS&D industries from ISO compliance to identify the implications (of ever-changing requirements) through an online survey of 15,000 practitioners. The research illuminated how ISO affects AS&D industries with current and future requirements for certification. The data showed that 75% of survey respondents report implementation of the AS9100C requirements still has benefits that outweigh the cost. Findings suggest that AS&D industries perceive significant value in the AS9100C document as part of the overall ISO 9000 series. In general, the comments from the survey can provide insight into the affects of ISO certification. The study concludes by recommending continued research to learn of further impacts from ISO certification within AS&D industries to improve the AS9100 document requirements for quality management systems.

  7. The Transracial Adoption Paradox

    PubMed Central

    Lee, Richard M.

    2008-01-01

    The number of transracial adoptions in the United States, particularly international adoptions, is increasing annually. Counseling psychology as a profession, however, is a relatively silent voice in the research on and practice of transracial adoption. This article presents an overview of the history and research on transracial adoption to inform counseling psychologists of the set of racial and ethnic challenges and opportunities that transracial adoptive families face in everyday living. Particular attention is given to emergent theory and research on the cultural socialization process within these families. PMID:18458794

  8. Standardization and future directions in pattern identification research: International brainstorming session.

    PubMed

    Jung, Jeeyoun; Park, Bongki; Lee, Ju Ah; You, Sooseong; Alraek, Terje; Bian, Zhao-Xiang; Birch, Stephen; Kim, Tae-Hun; Xu, Hao; Zaslawski, Chris; Kang, Byoung-Kab; Lee, Myeong Soo

    2016-09-01

    An international brainstorming session on standardizing pattern identification (PI) was held at the Korea Institute of Oriental Medicine on October 1, 2013 in Daejeon, South Korea. This brainstorming session was convened to gather insights from international traditional East Asian medicine specialists regarding PI standardization. With eight presentations and discussion sessions, the meeting allowed participants to discuss research methods and diagnostic systems used in traditional medicine for PI. One speaker presented a talk titled "The diagnostic criteria for blood stasis syndrome: implications for standardization of PI". Four speakers presented on future strategies and objective measurement tools that could be used in PI research. Later, participants shared information and methodology for accurate diagnosis and PI. They also discussed the necessity for standardizing PI and methods for international collaborations in pattern research.

  9. Ethical issues in tissue banking for research: the prospects and pitfalls of setting international standards.

    PubMed

    Maschke, Karen J; Murray, Thomas H

    2004-01-01

    Bauer, Taub, and Parsi's review of an international sample of standards on informed consent, confidentiality, commercialization, and quality of research in tissue banking reveals that no clear national or international consensus exists for these issues. The authors' response to the lack of uniformity in the meaning, scope, and ethical significance of the policies they examined is to call for the creation of uniform ethical guidelines. This raises questions about whether harmonization should consist of voluntary international standards or international regulations that include an official oversight mechanism and sanctions for noncompliance, and about who should participate in the harmonization process. Moreover, the normative assumptions and political dynamics that shape global policymaking need to be addressed. This commentary explores the policy implications and normative questions raised by the idea of international ethical guidelines for the use of biotechnologies and biotechnological resources such as stored samples of human tissue.

  10. [International Standards of Tuberculosis Care (ISTC)--comments from the German point of view].

    PubMed

    Castell, S; Bauer, T; Diel, R; Hedrich, A; Magdorf, K; Rüsch-Gerdes, S; Schaberg, T; Loddenkemper, R

    2012-04-01

    The "International Standards for Tuberculosis Care" (ISTC) were developed by the World Health Organisation (WHO) and others to provide internationally agreed and, if possible, evidence-based standards for tuberculosis care including the care by private providers who are not part of national tuberculosis programmes or health-care systems. Hence, the ISTC primarily address resource-restrained countries with high tuberculosis prevalence. In this article, the German translation of the 21 standards from 2009 is presented - addressing diagnostic and therapeutic standards, co-infection (especially with HIV) and public-health issues. The accompanying comments show how these standards have to be modified for Germany due to the medical resources available here and country-specific characteristics respectively.

  11. ASTM international workshop on standards and measurements for tissue engineering scaffolds.

    PubMed

    Simon, Carl G; Yaszemski, Michael J; Ratcliffe, Anthony; Tomlins, Paul; Luginbuehl, Reto; Tesk, John A

    2015-07-01

    The "Workshop on Standards & Measurements for Tissue Engineering Scaffolds" was held on May 21, 2013 in Indianapolis, IN, and was sponsored by the ASTM International (ASTM). The purpose of the workshop was to identify the highest priority items for future standards work for scaffolds used in the development and manufacture of tissue engineered medical products (TEMPs). Eighteen speakers and 78 attendees met to assess current scaffold standards and to prioritize needs for future standards. A key finding was that the ASTM TEMPs subcommittees (F04.41-46) have many active "guide" documents for educational purposes, but few standard "test methods" or "practices." Overwhelmingly, the most clearly identified need was standards for measuring the structure of scaffolds, followed by standards for biological characterization, including in vitro testing, animal models and cell-material interactions. The third most pressing need was to develop standards for assessing the mechanical properties of scaffolds. Additional needs included standards for assessing scaffold degradation, clinical outcomes with scaffolds, effects of sterilization on scaffolds, scaffold composition, and drug release from scaffolds. Discussions highlighted the need for additional scaffold reference materials and the need to use them for measurement traceability. Workshop participants emphasized the need to promote the use of standards in scaffold fabrication, characterization, and commercialization. Finally, participants noted that standards would be more broadly accepted if their impact in the TEMPs community could be quantified. Many scaffold standard needs have been identified and focus is turning to generating these standards to support the use of scaffolds in TEMPs.

  12. Adopting an International Innovation for Teacher Professional Development: State and District Approaches to Lesson Study in Florida

    ERIC Educational Resources Information Center

    Akiba, Motoko; Wilkinson, Bryan

    2016-01-01

    The state of Florida has taken an unprecedented approach to teacher professional development in its Race to the Top (RTTT) Program application by proposing to promote an international innovation that originates in Japan, "lesson study," as a statewide teacher professional development model. Since winning the US$700 million RTTT funding…

  13. Trace iodine quantitation in biological samples by mass spectrometric methods: the optimum internal standard.

    PubMed

    Dyke, Jason V; Dasgupta, Purnendu K; Kirk, Andrea B

    2009-07-15

    Accurate quantitation of iodine in biological samples is essential for studies of nutrition and medicine, as well as for epidemiological studies for monitoring intake of this essential nutrient. Despite the importance of accurate measurement, a standardized method for iodine analysis of biological samples is yet to be established. We have evaluated the effectiveness of (72)Ge, (115)In, and (129)I as internal standards for measurement of iodine in milk and urine samples by induction coupled plasma mass spectrometry (ICP-MS) and of (35)Cl(18)O(4)(-), (129)I(-), and 2-chlorobenzenesulfonate (2-CBS) as internal standards for ion chromatography-tandem mass spectrometry (IC-MS/MS). We found recovery of iodine to be markedly low when IC-MS/MS was used without an internal standard. Percent recovery was similarly low using (35)Cl(18)O(4) as an internal standard for milk and unpredictable when used for urine. 2-Chlorobenzebenzenesulfonate provided accurate recovery of iodine from milk, but overestimated iodine in urine samples by as much as a factor of 2. Percent recovery of iodine from milk and urine using ICP-MS without an internal standard was approximately 120%. Use of (115)In predicted approximately 60% of known values for both milk and urine samples. (72)Ge provided reasonable and consistent percent recovery for iodine in milk samples (approximately 108%) but resulted in approximately 80% recovery of iodine from urine. Use of (129)I as an internal standard resulted in excellent recovery of iodine from both milk and urine samples using either IC-MS/MS and ICP-MS.

  14. International standards: the World Organisation for Animal Health Terrestrial Animal Health Code.

    PubMed

    Thiermann, A B

    2015-04-01

    This paper provides a description of the international standards contained in the TerrestrialAnimal Health Code of the World Organisation for Animal Health (OIE) that relate to the prevention and control of vector-borne diseases. It identifies the rights and obligations of OIE Member Countries regarding the notification of animal disease occurrences, as well as the recommendations to be followed for a safe and efficient international trade of animals and their products.

  15. Open System Interconnection - NASA program communications of the future. [developed by International aorganization for Standardization

    NASA Technical Reports Server (NTRS)

    Brady, Charles D.

    1987-01-01

    Open Systems Interconnection (OSI) standards are being developed by the ISO and the Consultative Committee on International Telephone and Telegraph with the support of industry. These standards are being developed to allow the interconnecting of computer systems and the interworking of applications such that the applications can be independent of any equipment manufacturer. Significant progress has been made, and the establishment of government OSI standards is being considered. There is considerable interest within NASA in the potential benefits of OSI and in communications standards in general. The OSI standards are being considered for possible application in the Space Station onboard data management system. The OSI standards have reached a high level of maturity, and it is now imperative that NASA plan for future migration to OSI where appropriate.

  16. A change of course: The importance to DoD of international standards for electronic commerce

    NASA Astrophysics Data System (ADS)

    Payne, Judith E.

    1991-12-01

    The U.S. Department of Defense (DoD) is committed to using electronic commerce in the future with the over 300,000 vendors interested in doing business with DoD. Electronic commerce will move DoD from a paper-based world to one based on electronic transactions enabled by the exchange of formatted, electronic messages referred to as electronic data interchange (EDI). With electronic commerce, DoD plans to reduce costs, increase effectiveness, and make it easier for vendors to deal with DoD. Benefits from electronic commerce are enhanced when many businesses use the same standards for EDI messages themselves and their transmission. The fewer standards used, the less time and resources must be spent translating messages and agreeing on how to use different standards. To enhance benefits and smooth the transition to electronic commerce for itself and its vendors, DoD has chosen to use the widely accepted American National Standards Institute (ANSI) X12 standards for EDI messages, coupled with international standards for delivering messages and organizing addresses. In the past 18 months, EDI standards sponsored by a United Nations body and serving the same purpose as ANSI X12 message standards have begun to gain wider acceptance internationally.

  17. International standards related to the classification and deregulation of radioactive waste.

    PubMed

    Linsley, Gordon

    2006-11-01

    Although solid radioactive waste management is mainly a national concern, there are some aspects that have international implications. One important example is the decommissioning of nuclear facilities, which results in the release of materials that could be reused and recycled. It is possible that these materials could enter international trade, especially if the material is a metal. It is clearly desirable, therefore, to have appropriate international standards to help regulate trade. This paper describes recent international developments relating to the establishment of radiological criteria for the release of materials from regulatory control (clearance). There have already been some experiences of clearance and the transfer of recycled materials within Europe, and this paper reviews that experience. It also discusses recent developments in relation to the international classification of radioactive waste. PMID:17033457

  18. 25 CFR 542.17 - What are the minimum internal control standards for complimentary services or items?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... issued. (c) The internal audit or accounting departments shall review the reports required in paragraph... 25 Indians 2 2010-04-01 2010-04-01 false What are the minimum internal control standards for... THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.17 What are the minimum...

  19. 25 CFR 543.14 - What are the minimum internal control standards for patron deposit accounts and cashless systems?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are the minimum internal control standards for patron deposit accounts and cashless systems? 543.14 Section 543.14 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING § 543.14 What are the minimum internal...

  20. 25 CFR 542.4 - How do these regulations affect minimum internal control standards established in a Tribal-State...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How do these regulations affect minimum internal control... COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.4 How do these regulations affect minimum internal control standards established in a Tribal-State compact? (a) If there is...

  1. Measurement of Henry's Law Constants Using Internal Standards: A Quantitative GC Experiment for the Instrumental Analysis or Environmental Chemistry Laboratory

    ERIC Educational Resources Information Center

    Ji, Chang; Boisvert, Susanne M.; Arida, Ann-Marie C.; Day, Shannon E.

    2008-01-01

    An internal standard method applicable to undergraduate instrumental analysis or environmental chemistry laboratory has been designed and tested to determine the Henry's law constants for a series of alkyl nitriles. In this method, a mixture of the analytes and an internal standard is prepared and used to make a standard solution (organic solvent)…

  2. Guide to International Academic Standards for Athletics Eligibility for Students Entering Fall 2007

    ERIC Educational Resources Information Center

    Mills, Lisa; Nguyen, Binh; Auten, Lisa

    2007-01-01

    The "NCAA Guide to International Academic Standards for Athletics Eligibility" provides specific criteria to be used as a guide in reviewing the initial eligibility (graduation, core curriculum, grade-point average and ACT/SAT test scores) of students who have completed any portion of their secondary education in a non-United States educational…

  3. 25 CFR 543.24 - What are the minimum internal control standards for auditing revenue?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... auditing revenue? 543.24 Section 543.24 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING § 543.24 What are the...) noted by the Class II gaming system for cashless transactions in and out, electronic funds transfer...

  4. 25 CFR 543.24 - What are the minimum internal control standards for auditing revenue?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... auditing revenue? 543.24 Section 543.24 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING § 543.24 What are the...) noted by the Class II gaming system for cashless transactions in and out, electronic funds transfer...

  5. The Effect of International Financial Reporting Standards Convergence on U. S. Accounting Curriculum

    ERIC Educational Resources Information Center

    Bates, Homer L.; Waldrup, Bobby E.; Shea, Vincent

    2011-01-01

    Major changes are coming to U.S. financial accounting and accounting education as U. S. generally accepted accounting principles (GAAP) and international financial reporting standards (IFRS) converge within the next few years. In 2008, the U.S. Securities and Exchange Commission (SEC) published a proposed "road map" for the potential…

  6. Using ASBO International's Standards To Map Your Professional Growth and Development Plan.

    ERIC Educational Resources Information Center

    Stratton, Susan

    2002-01-01

    Explores various definitions of what constitutes a profession and what characteristics determine a professional. Identifies the need for continued professional growth and development related to the new Association of School Business Officials, International, "Professional Standards" (2001). Examples illustrate how individual school business…

  7. Functional Competency Development Model for Academic Personnel Based on International Professional Qualification Standards in Computing Field

    ERIC Educational Resources Information Center

    Tumthong, Suwut; Piriyasurawong, Pullop; Jeerangsuwan, Namon

    2016-01-01

    This research proposes a functional competency development model for academic personnel based on international professional qualification standards in computing field and examines the appropriateness of the model. Specifically, the model consists of three key components which are: 1) functional competency development model, 2) blended training…

  8. 78 FR 54606 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... standards of performance (``NSPS'') for stationary internal combustion engines (ICE) (78 FR 6674). Following... stationary RICE on March 3, 2010, (75 FR 9648) and August 20, 2010 (75 FR 51570). The EPA received petitions... of the final NESHAP and NSPS for stationary RICE (78 FR 6674, January 30, 2013). The Office...

  9. Evaluation of Vocational Services Provided to Jordanian Disabled People According to International Standards

    ERIC Educational Resources Information Center

    Al-Oweidi, Alia

    2015-01-01

    The purpose of the study is to evaluate the vocational rehabilitation services provided to people with disabilities according to international standards in Jordan. The sample of the study consisted of (56) managers and teachers in four specialized centers in vocational rehabilitation. The findings showed that the compatibility degree ranged…

  10. The Impact of International Financial Reporting Standards on Accounting Curriculum in the United States

    ERIC Educational Resources Information Center

    Yallapragada, RamMohan R.; Toma, Alfred G.; Roe, C. William

    2011-01-01

    According to the time line presently specified by the Securities and Exchange Commission (SEC), business firms in the United States (US) should switch from the existing US accounting reporting guidelines of the Generally Accepted Accounting Principles (GAAP) to International Financial Reporting Standards (IFRS) by the year 2014. The US business…

  11. Affirming the Goal: Is College and Career Readiness an Internationally Competitive Standard?

    ERIC Educational Resources Information Center

    ACT, Inc., 2011

    2011-01-01

    This report examines how performance standards in reading and math on PLAN[R], the organization's college and career readiness assessment for 10th graders, compare to performance on the Programme for International Student Assessment (PISA), a worldwide assessment of 15-year-old students' academic achievement. The results show that the performance…

  12. An Exploratory Study of the Perceptions of AACSB International's 2013 Accreditation Standards

    ERIC Educational Resources Information Center

    Miles, Morgan P.; Franklin, Geralyn McClure; Grimmer, Martin; Heriot, Kirl C.

    2015-01-01

    Purpose: The purpose of this paper is to report on the findings of an exploratory survey designed to measure AACSB member deans' perceptions about the recently revised 2013 Association to Advance Collegiate Schools of Business (AACSB) Accreditation Standards. In April of 2013, AACSB International released a major revision of its accreditation…

  13. 76 FR 70062 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HOMELAND SECURITY Coast Guard 46 CFR Parts 160, 180, and 199 RIN 1625-AB46 Lifesaving Equipment: Production Testing and Harmonization With International Standards Correction In rule document 2011-25035, appearing...

  14. Enhanced spectrophotometric determination of chromium (VI) with diphenylcarbazide using internal standard and derivative spectrophotometry.

    PubMed

    Wróbel, K; Wróbel, K; López-de-Alba, P L; López-Martínez, L

    1997-11-01

    In the present work, erioglaucine A was applied as internal standard to enhanced spectrophotometric determination of chromium (VI) with diphenylcarbazide. The following procedure was used: (1) addition of internal standard and formation of ion pairs of Cr (VI) with benzyltributylammonium bromide (BTAB) (sample volume 100 ml), (2) extraction to 10 ml of methylene chloride, (3) evaporation in nitrogen stream, and (4) redissolution in a micro-volume with addition of diphenylcarbazide for color development (final volume 200 mul). The preconcentration factor achieved was about 400 and it was shown that, using internal standard, the analytical errors due to sample treatment were reduced. The analytical signals for chromium and internal standard were obtained at 591.30 and 653.50 nm from first derivative spectra, normalized against (1)D(653.50nm). The analytical characteristics evaluated were: detection limit = 0.06 mug l(-1), quantification limit = 0.19 mug l(-1), precision for 1 mug l(-1) 14.2%, and for 10 mug l(-1) 3.2%, correlation coefficient of linear regression was 0.9985. The proposed procedure was applied to determination of chromium (VI) in tap water. Total chromium was determined by electrothermal atomic absorption spectrometry, the recovery of hexavalent chromium added was then evaluated and compared with the results of the proposed procedure. In this experiment, good agreement was obtained between results obtained by the two methods. PMID:18966962

  15. A Principles-Based Approach to Teaching International Financial Reporting Standards (IFRS)

    ERIC Educational Resources Information Center

    Persons, Obeua

    2014-01-01

    This article discusses the principles-based approach that emphasizes a "why" question by using the International Accounting Standards Board (IASB) "Conceptual Framework for Financial Reporting" to question and understand the basis for specific differences between IFRS and U.S. generally accepted accounting principles (U.S.…

  16. Differences in Students' Reading Comprehension of International Financial Reporting Standards: A South African Case

    ERIC Educational Resources Information Center

    Coetzee, Stephen A.; Janse van Rensburg, Cecile; Schmulian, Astrid

    2016-01-01

    This study explores differences in students' reading comprehension of International Financial Reporting Standards in a South African financial reporting class with a heterogeneous student cohort. Statistically significant differences were identified for prior academic performance, language of instruction, first language and enrolment in the…

  17. Calibration of replacement international standard and European Pharmacopoeia Biological Reference Preparation for Diphtheria Toxoid, Adsorbed.

    PubMed

    Sesardic, D; Winsnes, R; Rigsby, P; Gaines-Das, R

    2001-06-01

    We report here the characterisation of a preparation of diphtheria toxoid, adsorbed, and its calibration by twenty laboratories in fourteen countries in terms of the Second International Standard (I.S.) for Diphtheria Toxoid, Adsorbed, coded sample A (DIXA) using the established World Health Organisation (WHO)/European Pharmacopoeia (Ph Eur) challenge methods. The replacement standard preparation was found to have a unitage of 160 IU/ampoule on the basis of its calibration by in vivo bioassay. Stability was assessed within the collaborative study, and as part of candidate characterisation. Results suggest that the replacement standard will have satisfactory stability. This study also provided an opportunity to investigate serology as alternative to in vivo bioassay for potency testing of diphtheria vaccines. Six laboratories participated by performing serology according to in-house protocol. The calibration of the replacement standard in a mouse Vero cell assay gave a significantly higher results than in the established WHO/Ph Eur methods. Based on the results of this study and with the agreement of participants, the candidate standard was established as the Third International Standard for Diphtheria Toxoid, Adsorbed (coded 98/560) by the WHO Expert Committee of Biological Standardization in October 1999. The same preparation was also established as the second Ph Eur Biological Reference Preparation (Ph Eur BRP, batch no. 3) by the Steering Committee of the Biological Standardisation Programme of the European Directorate for the Quality of Medicines and approved by the European Pharmacopoeia Commission.

  18. Possible applications of atomic frequency standards with an internal high resolution digital synthesizer

    NASA Technical Reports Server (NTRS)

    Detoma, E.; Stern, A.

    1993-01-01

    The applications of Atomic Frequency Standards with an internal synthesizer (thereafter referred as 'Synthesized Frequency Standards or Oscillators') with a special emphasis on the Rb oscillator are reviewed. A fractional frequency synthesizer, developed by SEPA, was incorporated in the Frequency Locked Loop of a TFL Rubidium Frequency Standard. This combination allows a frequency settability in steps of 1.5 x 10(exp -12) (optional 1 x 10(exp -13) over a range of 6 x 10(exp -9) without having to resort to change the C-field to tune the output frequency of the device. This capability, coupled to the excellent short term stability of the Rb frequency standard, opens new possibilities for time and frequency users in the various fields (time metrology, navigation, communication, etc.) in which stable frequency standards find their application.

  19. CCSDS Advanced Orbiting Systems - International data communications standards for the Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Hooke, Adrian J.

    1990-01-01

    Established in 1982, the Consultative Committee for Space Data Systems (CCSDS) is an international organization that is staffed by data-handling experts from nearly all of the world's major space agencies. Its goal is to develop standard data-communications techniques so that several agencies may cross-support each other's data flow and thus allow complex, international missions to be flown. Under the general umbrella of Advanced Orbiting Systems (AOS), an international CCSDS task force was formed in 1985 to develop standard data-communications concepts for manned missions, such as the Space Station Freedom and the Hermes space plane, and large unmanned vehicles, such as polar orbiting platforms. The history of the CCSDS and the development of the AOS recommendation are reviewed, and the user services and protocols embodied in its systems architecture are introduced.

  20. Evaluation of mechanical properties of structural materials at cryogenic temperatures and international standardization for those methods

    NASA Astrophysics Data System (ADS)

    Ogata, T.

    2014-01-01

    Testing methods for mechanical properties of structural materials at cryogenic temperatures had been developed rapidly after 1980, however, until 1985 many researches on cryogenic structural materials have been reported using their own methods and new materials have been developed for ITER. Since 1986, a series of international inter-laboratory comparisons on the evaluation of mechanical properties of cryogenic structural materials have been performed among the participants of US-Japan cooperation project and VAMAS (the Versailles Project on Advanced Materials and Standards) in order to establish unified test methods. Through these international collaborations and Round-Robin Tests, we have accumulated knowledge about mechanical tests at 4 K, and have prepared a draft of an international standard for tensile testing in liquid helium. After testing conditions, strain measurements and other technical points have been discussed, those drafts were submitted to ISO. The outline, development, and discussion of the documents so far, with the results of RRTs, were discussed.

  1. Concept of Draft International Standard for a Unified Approach to Space Program Quality Assurance

    NASA Astrophysics Data System (ADS)

    Stryzhak, Y.; Vasilina, V.; Kurbatov, V.

    2002-01-01

    For want of the unified approach to guaranteed space project and product quality assurance, implementation of many international space programs has become a challenge. Globalization of aerospace industry and participation of various international ventures with diverse quality assurance requirements in big international space programs requires for urgent generation of unified international standards related to this field. To ensure successful fulfillment of space missions, aerospace companies should design and process reliable and safe products with properties complying or bettering User's (or Customer's) requirements. Quality of the products designed or processed by subcontractors (or other suppliers) should also be in compliance with the main user (customer)'s requirements. Implementation of this involved set of unified requirements will be made possible by creating and approving a system (series) of international standards under a generic title Space Product Quality Assurance based on a system consensus principle. Conceptual features of the baseline standard in this system (series) should comprise: - Procedures for ISO 9000, CEN and ECSS requirements adaptation and introduction into space product creation, design, manufacture, testing and operation; - Procedures for quality assurance at initial (design) phases of space programs, with a decision on the end product made based on the principle of independence; - Procedures to arrange incoming inspection of products delivered by subcontractors (including testing, audit of supplier's procedures, review of supplier's documentation), and space product certification; - Procedures to identify materials and primary products applied; - Procedures for quality system audit at the component part, primary product and materials supplier facilities; - Unified procedures to form a list of basic performances to be under configuration management; - Unified procedures to form a list of critical space product components, and unified

  2. World Health Organization International Standard to Harmonize Assays for Detection of Hepatitis E Virus RNA

    PubMed Central

    Blümel, Johannes; Mizusawa, Saeko; Matsubayashi, Keiji; Sakata, Hidekatsu; Okada, Yoshiaki; Nübling, C. Micha; Hanschmann, Kay-Martin O.

    2013-01-01

    Nucleic acid amplification technique–based assays are a primary method for the detection of acute hepatitis E virus (HEV) infection, but assay sensitivity can vary widely. To improve interlaboratory results for the detection and quantification of HEV RNA, a candidate World Health Organization (WHO) International Standard (IS) strain was evaluated in a collaborative study involving 23 laboratories from 10 countries. The IS, code number 6329/10, was formulated by using a genotype 3a HEV strain from a blood donation, diluted in pooled human plasma and lyophilized. A Japanese national standard, representing a genotype 3b HEV strain, was prepared and evaluated in parallel. The potencies of the standards were determined by qualitative and quantitative assays. Assay variability was substantially reduced when HEV RNA concentrations were expressed relative to the IS. Thus, WHO has established 6329/10 as the IS for HEV RNA, with a unitage of 250,000 International Units per milliliter. PMID:23647659

  3. Adopted: A practical salinity scale

    NASA Astrophysics Data System (ADS)

    The Unesco/ICES/SCOR/IAPSO Joint Panel on Oceanographic Tables and Standards has recommended the adoption of a Practical Salinity Scale, 1978, and a corresponding new International Equation of State of Seawater, 1980. A full account of the research leading to their recommendation is available in the series Unesco Technical Papers in Marine Science.The parent organizations have accepted the panel's recommendations and have set January 1, 1982, as the date when the new procedures, formulae, and tables should replace those now in use.

  4. Concept for an International Standard related to Space Weather Effects on Space Systems

    NASA Astrophysics Data System (ADS)

    Tobiska, W. Kent; Tomky, Alyssa

    There is great interest in developing an international standard related to space weather in order to specify the tools and parameters needed for space systems operations. In particular, a standard is important for satellite operators who may not be familiar with space weather. In addition, there are others who participate in space systems operations that would also benefit from such a document. For example, the developers of software systems that provide LEO satellite orbit determination, radio communication availability for scintillation events (GEO-to-ground L and UHF bands), GPS uncertainties, and the radiation environment from ground-to-space for commercial space tourism. These groups require recent historical data, current epoch specification, and forecast of space weather events into their automated or manual systems. Other examples are national government agencies that rely on space weather data provided by their organizations such as those represented in the International Space Environment Service (ISES) group of 14 national agencies. Designers, manufacturers, and launchers of space systems require real-time, operational space weather parameters that can be measured, monitored, or built into automated systems. Thus, a broad scope for the document will provide a useful international standard product to a variety of engineering and science domains. The structure of the document should contain a well-defined scope, consensus space weather terms and definitions, and internationally accepted descriptions of the main elements of space weather, its sources, and its effects upon space systems. Appendices will be useful for describing expanded material such as guidelines on how to use the standard, how to obtain specific space weather parameters, and short but detailed descriptions such as when best to use some parameters and not others; appendices provide a path for easily updating the standard since the domain of space weather is rapidly changing with new advances

  5. Defining the Core Archive Data Standards of the International Planetary Data Alliance (IPDA)

    NASA Technical Reports Server (NTRS)

    Hughes, J. Steven; Crichton, Dan; Beebe, Reta; Guinness, Ed; Heather, David; Zender, Joe

    2007-01-01

    A goal of the International Planetary Data Alliance (lPDA) is to develop a set of archive data standards that enable the sharing of scientific data across international agencies and missions. To help achieve this goal, the IPDA steering committee initiated a six month proj ect to write requirements for and draft an information model based on the Planetary Data System (PDS) archive data standards. The project had a special emphasis on data formats. A set of use case scenarios were first developed from which a set of requirements were derived for the IPDA archive data standards. The special emphasis on data formats was addressed by identifying data formats that have been used by PDS nodes and other agencies in the creation of successful data sets for the Planetary Data System (PDS). The dependency of the IPDA information model on the PDS archive standards required the compilation of a formal specification of the archive standards currently in use by the PDS. An ontology modelling tool was chosen to capture the information model from various sources including the Planetary Science Data Dictionary [I] and the PDS Standards Reference [2]. Exports of the modelling information from the tool database were used to produce the information model document using an object-oriented notation for presenting the model. The tool exports can also be used for software development and are directly accessible by semantic web applications.

  6. Rabies vaccine standards: comparison of the 5th and 6th WHO international reference standards to the USDA veterinary reference standard.

    PubMed

    Hermann, J; Fry, A; Reising, M; Patterson, P; Siev, D; Gatewood, D

    2012-11-01

    Ensuring rabies vaccines are potent and effective is paramount in preventing transmission of this deadly disease and safeguarding public health. Efficacy of human and veterinary vaccines is ensured by evaluating relative potency estimates of the vaccine compared to a rabies reference standard using the National Institutes of Health (NIH) test. Reference vaccines are based on the International Standard for Rabies Vaccine provided by the World Health Organization (WHO). A comparison study was conducted to determine the relative potency of the 5th WHO, 6th WHO, and United States Department of Agriculture's (USDA) 08-14 reference standards using the NIH test. Results from the study demonstrate that the 6th WHO reference standard is approximately twice as potent as the 5th WHO reference when reconstituted to contain 1 IU per ml. Based on these results, the Center for Veterinary Biologics (CVB) doubled the reconstitution volume of USDA veterinary reference 08-14 from 13 ml to 26 ml, for an initial use dilution of 0.7 IU per ml for use by veterinary biologics manufacturers in the NIH test. This study emphasizes the importance of reference standard calibration for use in the National Institutes of Health test.

  7. International standards for the exploration and production industry -- Their development and use

    SciTech Connect

    Johansen, A.R.; Loppinet, A.; Reeve, P.T.N.; Thomas, G.A.N.; Thorp, G.; Vanzini, R.

    1995-12-01

    A single global market for procurement is of crucial importance to the E and P industry. The resulting benefits, including cost reductions and shorter delivery times, could even be the key to the economic development of marginal fields. International Standards that cater for the needs of users, manufacturers and the public at large can provide a common basis for companies to procure and provide goods and services that will deliver the required performance throughout the field life. The savings to industry could be billions of dollars per year. The E and P Forum, on behalf of the industry, has developed proposals to increase the efficiency of this managerial procedure and to speed up the ``internationalization`` of selected standards. Details are given at the end of the paper. It is argued that the E and P industry should rally to the cause of international standardization. Companies should lend their full support by committing their valuable expert resources. It is in the interests of the industry to do this for, without suitably skilled expert representation in ISO and the elimination of duplication as well as waste of resources through performing similar work at company or national level, the large potential benefits of international standardization will elude the E and P industry.

  8. Proposed Standards for Medical Education Submissions to the Journal of General Internal Medicine

    PubMed Central

    Bowen, Judith L.; Gerrity, Martha S.; Kalet, Adina L.; Kogan, Jennifer R.; Spickard, Anderson; Wayne, Diane B.

    2008-01-01

    To help authors design rigorous studies and prepare clear and informative manuscripts, improve the transparency of editorial decisions, and raise the bar on educational scholarship, the Deputy Editors of the Journal of General Internal Medicine articulate standards for medical education submissions to the Journal. General standards include: (1) quality questions, (2) quality methods to match the questions, (3) insightful interpretation of findings, (4) transparent, unbiased reporting, and (5) attention to human subjects’ protection and ethical research conduct. Additional standards for specific study types are described. We hope these proposed standards will generate discussion that will foster their continued evolution. Electronic supplementary material The online version of this article (doi:10.1007/s11606-008-0676-z) contains supplementary material, which is available to authorized users. PMID:18612716

  9. [Limitations of occupational exposure to electromagnetic fields adopted by Polish law from the perspectives of international documents with particular reference to fields of low and medium frequencies].

    PubMed

    Karpowicz, Jolanta; Gryz, Krzysztof

    2003-01-01

    Following the provisions of the decree on maximum admissible strength (MAS) values, issued by the Minister of Labour and Social Policy, comprehensive and homogeneous principles of workers' protection against excessive exposure to 0-300 GHz electromagnetic fields have been in force since 2001. Different mechanisms responsible for interactions between electromagnetic field and human body, as well as the need to limit their harmful effects were taken into account while setting permissible exposure conditions. Owing to the fact that both the strength of electric and magnetic fields and exposure duration have been considered, Polish regulations facilitate a parallel harmonisation of the prohibited exposure levels with so-called "basic restriction" values adopted as a minimum protection level in many international guidelines and to implement a significantly higher level of workers' protection in case of long-duration per shift exposure (equivalent of "precautionary principle" applied in the evaluation of general public exposure). The approaches adopted in Polish regulations coincide in many points with a drafted EU directive. Amendments being introduced into Polish legal regulations on the environmental protection should maintain cohesion principle with legal regulations on occupational exposure to electromagnetic fields, and should take into account additional restrictions concerning the protection of residential areas, as practiced in many European countries.

  10. Does science speak clearly and fairly in trade and food safety disputes? The search for an optimal response of WTO adjudication to problematic international standard-making.

    PubMed

    Ni, Kuei-Jung

    2013-01-01

    Most international health-related standards are voluntary per se. However, the incorporation of international standard-making into WTO agreements like the SPS Agreement has drastically changed the status and effectiveness of the standards. WTO members are urged to follow international standards, even when not required to comply fully with them. Indeed, such standards have attained great influence in the trade system. Yet evidence shows that the credibility of the allegedly scientific approach of these international standard-setting institutions, especially the Codex Alimentarius Commission (Codex) governing food safety standards, has been eroded and diluted by industrial and political influences. Its decision-making is no longer based on consensus, but voting. The adoption of new safety limits for the veterinary drug ractopamine in 2012, by a very close vote, is simply another instance of the problematic operations of the Codex. These dynamics have led skeptics to question the legitimacy of the standard setting body and to propose solutions to rectify the situation. Prior WTO rulings have yet to pay attention to the defect in the decision-making processes of the Codex. Nevertheless, the recent Appellate Body decision on Hormones II is indicative of a deferential approach to national measures that are distinct from Codex formulas. The ruling also rejects the reliance on those experts who authored the Codex standards to assess new measures of the European Community. This approach provides an opportunity to contemplate what the proper relationship between the WTO and Codex ought to be. Through a critical review of WTO rulings and academic proposals, this article aims to analyze how the WTO ought to define such interactions and respond to the politicized standard-making process in an optimal manner. This article argues that building a more systematic approach and normative basis for WTO judicial review of standard-setting decisions and the selection of technical

  11. To recognize the use of international standards for making harmonized regulation of medical devices in Asia-pacific.

    PubMed

    Anand, K; Saini, Ks; Chopra, Y; Binod, Sk

    2010-07-01

    'Medical Devices' include everything from highly sophisticated, computerized, medical equipment, right down to simple wooden tongue depressors. Regulations embody the public expectations for how buildings and facilities are expected to perform and as such represent public policy. Regulators, who develop and enforce regulations, are empowered to act in the public's interest to set this policy and are ultimately responsible to the public in this regard. Standardization contributes to the basic infrastructure that underpins society including health and environment, while promoting sustainability and good regulatory practice. The international organizations that produce International Standards are the International Electrotechnical Commission (IEC), the International Organization for Standardization (ISO), and the International Telecommunication Union (ITU). With the increasing globalization of markets, International Standards (as opposed to regional or national standards) have become critical to the trading process, ensuring a level playing field for exports, and ensuring that imports meet the internationally recognized levels of performance and safety. The development of standards is done in response to sectors and stakeholders that express a clearly established need for them. An industry sector or other stakeholder group typically communicates its requirement for standards to one of the national members. To be accepted for development, a proposed work item must receive a majority support of the participating members, who verify the global relevance of the proposed item. The regulatory authority (RA) should provide a method for the recognition of international voluntary standards and for public notification of such recognition. The process of recognition may vary from country to country. Recognition may occur by periodic publication of lists of standards that a regulatory authority has found will meet the Essential Principles. In conclusion, International standards

  12. A decade of international cooperation brings a standard seismic point of view

    USGS Publications Warehouse

    Whitcomb, H. S

    1971-01-01

    Whether in a castle in Italy, a police station in Iceland, o an abandoned gold mine in Australia, the sensitive instruments in the Worldwide Seismograph Network send a steady flow of standard earthquake records to the geophysical scientific community. They provide the raw data that make possible very precise earthquake studies, precise because the instruments are identical and their product standard. A truly international program, this network of 115 stations in 61 countires and territories has laid the foundation for reserach in seismology for many years to come. 

  13. ISBD(S), International Standard Bibliographic Description for Serials; Recommended by the Joint Working Group on the International Standard Bibliographic Description for Serials set up by the IFLA Committee on Cataloguing and the IFLA Committee on Serial Publications.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, London (England). Committee on Cataloguing.

    The International Standard Bibliographic Description for Serials--ISBD(S)--provides a format for the international communication of bibliographic information so that records may be interchanged between sources, interpreted across language barriers, and converted to machine readable form. The ISBD(S) standards are limited to the descriptive…

  14. Improved Measurement Performance of Inorganic Elements in Coal by Laser-Induced Breakdown Spectroscopy Coupled with Internal Standardization

    NASA Astrophysics Data System (ADS)

    Yao, Shunchun; Xu, Jialong; Bai, Kaijie; Lu, Jidong

    2015-11-01

    Laser-induced breakdown spectroscopy was employed to determine the inorganic elements in coal. To improve the measurement's accuracy and precision, a new internal standardization scheme, which we named changed internal standardization, was compared with the traditional internal standardization and no internal standardization for the analysis of inorganic elements. The new internal standardization scheme used the atomic line of carbon at 247.86 nm and the molecular band of CN at 388.34 nm and C2 at 516.32 nm to normalize the lines of inorganic elements that were distributed in the same spectral channel. The performance of the utilization of the new internal standardization scheme was evaluated using a set of coal samples, including twenty calibration samples and five validation samples. The results show that the coefficients of determination R2 and the slope of calibration models coupled with changed internal standardization are better than that of the calibration models coupled with fixed internal standardization and no internal standardization. Moreover, the measurement accuracy and reproducibility of changed internal standardization for the analysis of five validation samples also yielded further improvement. The results that we obtained suggest that changed internal standardization could compensate for the matrix effects, as well as the influence of the difference in the spectral response of the light collection system. supported by Open Research Fund of State Key Laboratory of Pulsed Power Laser Technology of China (No. SKL2013KF03), National Natural Science Foundation of China (Nos. 51206055, 51476061), the Fundamental Research Funds for the Central Universities of China (No. 2014ZZ0014), the New Star of Pearl River on Science and Technology of Guangzhou, China (No. 2014J2200054), the Key Laboratory of Efficient and Clean Energy Utilization of Guangdong Higher Education Institutes of China (No. KLB10004) and Guangdong Province Key Laboratory of Efficient and

  15. Short tandem repeat profiling provides an international reference standard for human cell lines

    PubMed Central

    Masters, John R.; Thomson, Jim A.; Daly-Burns, Bernadette; Reid, Yvonne A.; Dirks, Wilhelm G.; Packer, Phil; Toji, Lorraine H.; Ohno, Tadao; Tanabe, Hideyuki; Arlett, Colin F.; Kelland, Lloyd R.; Harrison, Maureen; Virmani, Arvind; Ward, Timothy H.; Ayres, Karen L.; Debenham, Paul G.

    2001-01-01

    Cross-contamination between cell lines is a longstanding and frequent cause of scientific misrepresentation. Estimates from national testing services indicate that up to 36% of cell lines are of a different origin or species to that claimed. To test a standard method of cell line authentication, 253 human cell lines from banks and research institutes worldwide were analyzed by short tandem repeat profiling. The short tandem repeat profile is a simple numerical code that is reproducible between laboratories, is inexpensive, and can provide an international reference standard for every cell line. If DNA profiling of cell lines is accepted and demanded internationally, scientific misrepresentation because of cross-contamination can be largely eliminated. PMID:11416159

  16. Synthesis of stable isotope labelled internal standards for drug-drug interaction (DDI) studies.

    PubMed

    Atzrodt, J; Blankenstein, J; Brasseur, D; Calvo-Vicente, S; Denoux, M; Derdau, V; Lavisse, M; Perard, S; Roy, S; Sandvoss, M; Schofield, J; Zimmermann, J

    2012-09-15

    The syntheses of stable isotope labelled internal standards of important CYP-isoform selective probes, like testosterone 1, diclofenac 3, midazolam 5, and dextromethorphan 7, as well as their corresponding hydroxylated metabolites 6β-hydroxytestosterone 2, 4'-hydroxydiclofenac 4, 1'-hydroxymidazolam 6 and dextrorphan 8 are reported. Microwave-enhanced H/D-exchange reactions applying either acid, base, or homogeneous and heterogeneous transition metal catalysis, or combinations thereof proved to be highly efficient for direct deuterium labelling of the above mentioned probes. Compared to conventional stepwise synthetic approaches, the combination of H/D exchange and biotransformation provides the potential for considerable time- and cost savings, in particular for the synthesis of the stable isotope labelled internal standards of 4'-hydroxydiclofenac 4 and 1'-hydroxymidazolam 6. PMID:22890009

  17. Determination of acidity constants by the capillary electrophoresis internal standard method. IV. Polyprotic compounds.

    PubMed

    Cabot, Joan Marc; Fuguet, Elisabet; Ràfols, Clara; Rosés, Martí

    2013-03-01

    The IS-CE method is developed for pK(a) determination of polyprotic compounds. In this method, the internal standard (IS) and the polyprotic test compound are injected into the capillary electrophoresis (CE) system in buffers with appropriate pH. The pH of the buffers is not externally measured, but determined inside the capillary from the mobilities of the internal standards. Then the pK(a) values of the polyprotic compounds are obtained by fitting its mobilities to the in situ pH values. The method is faster than the classical CE method (a diprotic compound can be done in less than 15 min), and also than other methods like potentiometric and spectrophotometric titrations. The method has been successfully applied to 20 polyprotic test compounds of different chemical nature, including compounds with extreme or very close pK(a) values.

  18. Synthesis of stable isotope labelled internal standards for drug-drug interaction (DDI) studies.

    PubMed

    Atzrodt, J; Blankenstein, J; Brasseur, D; Calvo-Vicente, S; Denoux, M; Derdau, V; Lavisse, M; Perard, S; Roy, S; Sandvoss, M; Schofield, J; Zimmermann, J

    2012-09-15

    The syntheses of stable isotope labelled internal standards of important CYP-isoform selective probes, like testosterone 1, diclofenac 3, midazolam 5, and dextromethorphan 7, as well as their corresponding hydroxylated metabolites 6β-hydroxytestosterone 2, 4'-hydroxydiclofenac 4, 1'-hydroxymidazolam 6 and dextrorphan 8 are reported. Microwave-enhanced H/D-exchange reactions applying either acid, base, or homogeneous and heterogeneous transition metal catalysis, or combinations thereof proved to be highly efficient for direct deuterium labelling of the above mentioned probes. Compared to conventional stepwise synthetic approaches, the combination of H/D exchange and biotransformation provides the potential for considerable time- and cost savings, in particular for the synthesis of the stable isotope labelled internal standards of 4'-hydroxydiclofenac 4 and 1'-hydroxymidazolam 6.

  19. Towards internationally acceptable standards for food additives and contaminants based on the use of risk analysis.

    PubMed

    Huggett, A; Petersen, B J; Walker, R; Fisher, C E; Notermans, S H; Rombouts, F M; Abbott, P; Debackere, M; Hathaway, S C; Hecker, E F; Knaap, A G; Kuznesof, P M; Meyland, I; Moy, G; Narbonne, J F; Paakkanen, J; Smith, M R; Tennant, D; Wagstaffe, P; Wargo, J; Würtzen, G

    1998-06-01

    Internationally acceptable norms need to incorporate sound science and consistent risk management principles in an open and transparent manner, as set out in the Agreement on the Application of Sanitary and Phytosanitary Measures (the SPS Agreement). The process of risk analysis provides a procedure to reach these goals. The interaction between risk assessors and risk managers is considered vital to this procedure. This paper reports the outcome of a meeting of risk assessors and risk managers on specific aspects of risk analysis and its application to international standard setting for food additives and contaminants. Case studies on aflatoxins and aspartame were used to identify the key steps of the interaction process which ensure scientific justification for risk management decisions. A series of recommendations were proposed in order to enhance the scientific transparency in these critical phases of the standard setting procedure.

  20. Application of ISO standard 27048: dose assessment for the monitoring of workers for internal radiation exposure.

    PubMed

    Henrichs, K

    2011-03-01

    Besides ongoing developments in the dosimetry of incorporated radionuclides, there are various efforts to improve the monitoring of workers for potential or real intakes of radionuclides. The disillusioning experience with numerous intercomparison projects identified substantial differences between national regulations, concepts, applied programmes and methods, and dose assessment procedures. Measured activities were not directly comparable because of significant differences between measuring frequencies and methods, but also results of case studies for dose assessments revealed differences of orders of magnitude. Besides the general common interest in reliable monitoring results, at least the cross-border activities of workers (e.g. nuclear power plant services) require consistent approaches and comparable results. The International Standardization Organization therefore initiated projects to standardise programmes for the monitoring of workers, the requirements for measuring laboratories and the processes for the quantitative evaluation of monitoring results in terms of internal assessed doses. The strength of the concepts applied by the international working group consists in a unified approach defining the requirements, databases and processes. This paper is intended to give a short introduction into the standardization project followed by a more detailed description of the dose assessment standard, which will be published in the very near future. PMID:21212077

  1. World Health Organization International Standard To Harmonize Assays for Detection of Mycoplasma DNA.

    PubMed

    Nübling, C Micha; Baylis, Sally A; Hanschmann, Kay-Martin; Montag-Lessing, Thomas; Chudy, Michael; Kreß, Julia; Ulrych, Ursula; Czurda, Stefan; Rosengarten, Renate

    2015-09-01

    Nucleic acid amplification technique (NAT)-based assays (referred to here as NAT assays) are increasingly used as an alternative to culture-based approaches for the detection of mycoplasma contamination of cell cultures. Assay features, like the limit of detection or quantification, vary widely between different mycoplasma NAT assays. Biological reference materials may be useful for harmonization of mycoplasma NAT assays. An international feasibility study included lyophilized preparations of four distantly related mycoplasma species (Acholeplasma laidlawii, Mycoplasma fermentans, M. orale, M. pneumoniae) at different concentrations which were analyzed by 21 laboratories using 26 NAT assays with a qualitative, semiquantitative, or quantitative design. An M. fermentans preparation was shown to decrease the interassay variation when used as a common reference material. The preparation was remanufactured and characterized in a comparability study, and its potency (in NAT-detectable units) across different NATs was determined. The World Health Organization (WHO) Expert Committee on Biological Standardization (ECBS) established this preparation to be the "1st World Health Organization international standard for mycoplasma DNA for nucleic acid amplification technique-based assays designed for generic mycoplasma detection" (WHO Tech Rep Ser 987:42, 2014) with a potency of 200,000 IU/ml. This WHO international standard is now available as a reference preparation for characterization of NAT assays, e.g., for determination of analytic sensitivity, for calibration of quantitative assays in a common unitage, and for defining regulatory requirements in the field of mycoplasma testing.

  2. Starworld: Preparing Accountants for the Future: A Case-Based Approach to Teach International Financial Reporting Standards Using ERP Software

    ERIC Educational Resources Information Center

    Ragan, Joseph M.; Savino, Christopher J.; Parashac, Paul; Hosler, Jonathan C.

    2010-01-01

    International Financial Reporting Standards now constitute an important part of educating young professional accountants. This paper looks at a case based process to teach International Financial Reporting Standards using integrated Enterprise Resource Planning software. The case contained within the paper can be used within a variety of courses…

  3. International standards for tuberculosis care: relevance and implications for laboratory professionals.

    PubMed

    Pai, M; Daley, P; Hopewell, P C

    2007-04-01

    On World Tuberculosis (TB) Day 2006, the International Standards for Tuberculosis Care (ISTC) was officially released and widely endorsed by several agencies and organizations. The ISTC release was the culmination of a year long global effort to develop and set internationally acceptable, evidence-based standards for tuberculosis care. The ISTC describes a widely endorsed level of care that all practitioners, public and private, should seek to achieve in managing individuals who have or are suspected of having, TB and is intended to facilitate the effective engagement of all healthcare providers in delivering high quality care for patients of all ages, including those with smear-positive, smear-negative and extra-pulmonary TB, TB caused by drug-resistant Mycobacterium tuberculosis and TB/HIV coinfection. In this article, we present the ISTC, with a special focus on the diagnostic standards and describe their implications and relevance for laboratory professionals in India and worldwide. Laboratory professionals play a critical role in ensuring that all the standards are actually met by providing high quality laboratory services for smear microscopy, culture and drug susceptibility testing and other services such as testing for HIV infection. In fact, if the ISTC is widely followed, it can be expected that there will be a greater need and demand for quality assured laboratory services and this will have obvious implications for all laboratories in terms of work load, requirement for resources and trained personnel and organization of quality assurance systems. PMID:17582176

  4. Interpreting international governance standards for health IT use within general medical practice.

    PubMed

    Mahncke, Rachel J; Williams, Patricia A H

    2014-01-01

    General practices in Australia recognise the importance of comprehensive protective security measures. Some elements of information security governance are incorporated into recommended standards, however the governance component of information security is still insufficiently addressed in practice. The International Organistion for Standardisation (ISO) released a new global standard in May 2013 entitled, ISO/IEC 27014:2013 Information technology - Security techniques - Governance of information security. This standard, applicable to organisations of all sizes, offers a framework against which to assess and implement the governance components of information security. The standard demonstrates the relationship between governance and the management of information security, provides strategic principles and processes, and forms the basis for establishing a positive information security culture. An analysis interpretation of this standard for use in Australian general practice was performed. This work is unique as such interpretation for the Australian healthcare environment has not been undertaken before. It demonstrates an application of the standard at a strategic level to inform existing development of an information security governance framework.

  5. Selected Lessons Learned over the ISS Design, Development, Assembly, and Operations: Applicability to International Cooperation for Standardization

    NASA Technical Reports Server (NTRS)

    Hirsch, David B.

    2010-01-01

    This slide presentation reviews some of the lessons learned in the sphere of international cooperation during the development, assembly and operation of the International Space Station. From the begining all Partners shared a common objective to build, operate and utilize a crewed laboratory in low orbit as an international partnership. The importance of standards is emphasized.

  6. Prevalence of abnormal findings when adopting new national and international Global Lung Function Initiative reference values for spirometry in the Finnish general population

    PubMed Central

    Kainu, Annette; Lindqvist, Ari; Sovijärvi, Anssi R. A.

    2016-01-01

    Background New Finnish (Kainu2015) and international Global Lung Function Initiative (GLI2012) reference values for spirometry were recently published. The aim of this study is to compare the interpretative consequences of adopting these new reference values with older, currently used Finnish reference values (Viljanen1982) in the general population of native Finns. Methods Two Finnish general population samples including 1,328 adults (45% males) aged 21–74 years were evaluated. Airway obstruction was defined as a reduced ratio of forced expiratory volume in one second (FEV1)/forced vital capacity (FVC), possible restrictive pattern as reduced FVC, and decreased ventilatory capacity as reduced FEV1 below their respective 2.5th percentiles. The severity gradings of reduced lung function were also compared. Results Using the Kainu2015 reference values, the prevalence of airway obstruction in the population was 5.6%; using GLI2012 it was 4.0% and with Viljanen1982 it was 13.0%. Possible restrictive pattern was found in 4.2% using the Kainu2015 values, in 2.0% with GLI2012, and 7.9% with the Viljanen1982 values. The prevalence of decreased ventilatory capacity was 6.8, 4.0, and 13.3% with the Kainu2015, GLI2012 and Viljanen1982 values, respectively. Conclusions The application of the GLI2012 reference values underestimates the prevalence of abnormal spirometric findings in native Finns. The adoption of the Kainu2015 reference values reduces the prevalences of airways obstruction, decreased ventilatory capacity, and restrictive impairment by approximately 50%. Changing from the 2.5th percentile, the previously used lower limit of normal, to the 5th percentile recommended by the American Thoracic Society/European Respiratory Society will not increase the prevalence of abnormal findings in the implementation of spirometry reference values. PMID:27608270

  7. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    SciTech Connect

    Zhou, Nan; Zheng, Nina; Fridley, David

    2012-02-28

    Appliance energy efficiency standards and labeling (S&L) programs have been important policy tools for regulating the efficiency of energy-using products for over 40 years and continue to expand in terms of geographic and product coverage. The most common S&L programs include mandatory minimum energy performance standards (MEPS) that seek to push the market for efficient products, and energy information and endorsement labels that seek to pull the market. This study seeks to review and compare some of the earliest and most well-developed S&L programs in three countries and one region: the U.S. MEPS and ENERGY STAR, Australia MEPS and Energy Label, European Union MEPS and Ecodesign requirements and Energy Label and Japanese Top Runner programs. For each program, key elements of S&L programs are evaluated and comparative analyses across the programs undertaken to identify best practice examples of individual elements as well as cross-cutting factors for success and lessons learned in international S&L program development and implementation. The international review and comparative analysis identified several overarching themes and highlighted some common factors behind successful program elements. First, standard-setting and programmatic implementation can benefit significantly from a legal framework that stipulates a specific timeline or schedule for standard-setting and revision, product coverage and legal sanctions for non-compliance. Second, the different MEPS programs revealed similarities in targeting efficiency gains that are technically feasible and economically justified as the principle for choosing a standard level, in many cases at a level that no product on the current market could reach. Third, detailed survey data such as the U.S. Residential Energy Consumption Survey (RECS) and rigorous analyses provide a strong foundation for standard-setting while incorporating the participation of different groups of stakeholders further strengthen the process

  8. Quantitation of biological retinoids by high-pressure liquid chromatography: primary internal standardization using tritiated retinoids

    SciTech Connect

    Cullum, M.E.; Zile, M.H.

    1986-02-15

    A single method is described for quantitation of 14 retinoids found in biological material. The method consists of reversed-phase HPLC, internal standardization, and carrier extraction procedures with three synthetic retinoids. Primary standardization of HPLC uv detector is achieved using tritiated all-trans-retinoic acid, all-trans-retinol, all-trans-retinyl palmitate, and all-trans-retinyl acetate. Extraction methods are standardized by correlating the uv absorbance of retinoids at 340 nm with radioactivity of tritiated retinoids of known specific activity. Quantitation of 10 pg of tritiated or 5 ng of nonradioactive retinoid per 0.1 g sample in a polarity range from 4-oxo-retinoic acid to retinyl stearate can be achieved in a single, 50-min chromatographic run. A single HPLC pump, a C/sub 18/ reversed-phased analytical column, a multistep three-solvent gradient, and inexpensive solvents based on methanol, water, and chloroform comprise this cost-effective chromatographic system. Our primary standardization method allows investigators employing different procedures to compare results between laboratories by standardizing the HPLC uv detector with commercially available tritiated retinoids. With this method we were able to quantitate nanomolar amounts of endogenous retinoic acids and retinyl esters, that HPLC uv only conditions usually would not detect in the circulation and liver of rats under physiological conditions.

  9. Collaborative study for the calibration of a replacement International Standard for Tetanus Toxoid Adsorbed.

    PubMed

    Tierney, Rob; Stickings, Paul; Hockley, Jason; Rigsby, Peter; Iwaki, Masaaki; Sesardic, Dorothea

    2011-11-01

    We present the results of a collaborative study for the establishment of a replacement International Standard (IS) for Tetanus Toxoid Adsorbed. Two candidate preparations were included in the study, one of which was established as the 4th IS for Tetanus Toxoid Adsorbed at the WHO Expert Committee on Biological Standardization meeting in October 2010. This preparation was found to have a unitage of 490 IU/ampoule, based on calibration in guinea pig challenge assays. Results from mouse challenge assays suggest that the relative performance of two candidate preparations may differ significantly between guinea pigs and mice. The authors note that the number of laboratories that performed guinea pig challenge assays, which are used to calibrate and assign IU, is much lower than in previous collaborative studies and this may have implications for calibration of replacement standards in the future. The issue of assigning separate units to the IS for guinea pig and mouse assays is discussed. The study also assessed performance of the replacement standard in serological assays which are used as alternative procedures to challenge assays for tetanus potency testing. Results suggest that the replacement standard is suitable for use as the reference vaccine in serological assays.

  10. Commutability of the First World Health Organization International Standard for Human Cytomegalovirus

    PubMed Central

    Preiksaitis, J.; Tong, Y.; Pang, X.; Sun, Y.; Tang, L.; Cook, L.; Pounds, S.; Fryer, J.; Caliendo, A. M.

    2015-01-01

    Quantitative detection of cytomegalovirus (CMV) DNA has become a standard part of care for many groups of immunocompromised patients; recent development of the first WHO international standard for human CMV DNA has raised hopes of reducing interlaboratory variability of results. Commutability of reference material has been shown to be necessary if such material is to reduce variability among laboratories. Here we evaluated the commutability of the WHO standard using 10 different real-time quantitative CMV PCR assays run by eight different laboratories. Test panels, including aliquots of 50 patient samples (40 positive samples and 10 negative samples) and lyophilized CMV standard, were run, with each testing center using its own quantitative calibrators, reagents, and nucleic acid extraction methods. Commutability was assessed both on a pairwise basis and over the entire group of assays, using linear regression and correspondence analyses. Commutability of the WHO material differed among the tests that were evaluated, and these differences appeared to vary depending on the method of statistical analysis used and the cohort of assays included in the analysis. Depending on the methodology used, the WHO material showed poor or absent commutability with up to 50% of assays. Determination of commutability may require a multifaceted approach; the lack of commutability seen when using the WHO standard with several of the assays here suggests that further work is needed to bring us toward true consensus. PMID:26269622

  11. Upcoming new international measurement standards in the field of building acoustics

    NASA Astrophysics Data System (ADS)

    Goydke, Hans

    2002-11-01

    The extensively completed revision of most of the ISO measurement standards in building acoustics mainly initiated by the European Commissions demand for harmonized standards emphasized the insight that the main goal to avoid trade barriers between the countries can only be reached when the standards sufficiently and comprehensively cover the field when they are related to the actual state of the art and when they are sufficiently related to practice. In modern architecture one can observe the rapid change in the use of building materials, for instance regarding the use of glass. Lightweight constructions as well as heavyweight building elements with additional linings are increasingly in common use and unquestionably there are consequences to be considered regarding the ascertainment of sound insulation properties. Besides others, International Standardization is unsatisfactory regarding the assessment of noise in buildings from waste water installations, in the low frequency area and in general regarding the expression of uncertainty of measurements. Intensity measurements in building acoustics, rainfall noise assessment, estimation of sound insulation, impulse response measurement methods, assessment of sound scattering are examples of upcoming standards.

  12. The Meaning of Curriculum-Related Examination Standards in Scotland and England: A Home-International Comparison

    ERIC Educational Resources Information Center

    Baird, Jo-Anne; Gray, Lena

    2016-01-01

    The ways in which examination standards are conceptualised and operationalised differently across nations has not been given sufficient attention. The international literature on standard-setting has been dominated by the psychometrics tradition. Broader conceptualisations of examination standards have been discussed in the literature in England,…

  13. Standardizing Clinical Trials Workflow Representation in UML for International Site Comparison

    PubMed Central

    de Carvalho, Elias Cesar Araujo; Jayanti, Madhav Kishore; Batilana, Adelia Portero; Kozan, Andreia M. O.; Rodrigues, Maria J.; Shah, Jatin; Loures, Marco R.; Patil, Sunita; Payne, Philip; Pietrobon, Ricardo

    2010-01-01

    Background With the globalization of clinical trials, a growing emphasis has been placed on the standardization of the workflow in order to ensure the reproducibility and reliability of the overall trial. Despite the importance of workflow evaluation, to our knowledge no previous studies have attempted to adapt existing modeling languages to standardize the representation of clinical trials. Unified Modeling Language (UML) is a computational language that can be used to model operational workflow, and a UML profile can be developed to standardize UML models within a given domain. This paper's objective is to develop a UML profile to extend the UML Activity Diagram schema into the clinical trials domain, defining a standard representation for clinical trial workflow diagrams in UML. Methods Two Brazilian clinical trial sites in rheumatology and oncology were examined to model their workflow and collect time-motion data. UML modeling was conducted in Eclipse, and a UML profile was developed to incorporate information used in discrete event simulation software. Results Ethnographic observation revealed bottlenecks in workflow: these included tasks requiring full commitment of CRCs, transferring notes from paper to computers, deviations from standard operating procedures, and conflicts between different IT systems. Time-motion analysis revealed that nurses' activities took up the most time in the workflow and contained a high frequency of shorter duration activities. Administrative assistants performed more activities near the beginning and end of the workflow. Overall, clinical trial tasks had a greater frequency than clinic routines or other general activities. Conclusions This paper describes a method for modeling clinical trial workflow in UML and standardizing these workflow diagrams through a UML profile. In the increasingly global environment of clinical trials, the standardization of workflow modeling is a necessary precursor to conducting a comparative

  14. The Elevation of Annals of Rehabilitation Medicine to the Status of an International Journal After Adopting an English-Only Policy

    PubMed Central

    2015-01-01

    Objective To use bibliometric analyses to determine whether Annals of Rehabilitation Medicine (hereafter also referred to as Annals) became an international journal after adopting an English-only policy in 2011. Methods Articles from the third issue of 2011 to the third issue of 2015 were analyzed according to the following parameters: whether the research was supported by funding, country of authorship, impact factor, total citations, the countries of researchers who cited Annals; the journals that cited Annals; and the Hirsch index. Results One hundred twenty-eight (34.2%) of the 374 original articles were supported by research funds. The main authors were from Korea (550/556, 98.9%), the USA (3), Iran (2), Japan (1), Turkey (1), and the United Kingdom (1). The manually calculated impact factors in 2013 and 2014 were 0.582 and 0.667, respectively. The total annual citations from years 2012 to 2015 were 15, 130, 252, and 189, respectively. The countries of residence of the main authors who cited Annals were the USA (146), Korea (89), and China (49). The journals that cited Annals most frequently were the Journal of Physical Therapy (34), Archives of Physical Medicine and Rehabilitation (15), and Frontiers in Human Neuroscience (13). The Hirsch index was 9. Conclusion The above results demonstrate that the change of the language policy of Annals to English-only was successful in elevating the journal to the international level. The journal's aim of sharing up-to-date knowledge dedicated to advancing the care of the disabled and enhancing their everyday abilities and quality of life has been satisfactorily realized. PMID:26605163

  15. The URSI/COSPAR Standard for the Ionosphere: International Reference Ionosphere

    NASA Astrophysics Data System (ADS)

    Rawer, K.; Bilitza, D.; Reinisch, B.; Triskova, L.; Oyama, K.

    The International Reference Ionosphere (IRI) is the standard for ionospheric densities and temperatures recommended by the International Union of Radio science (URSI) and the Committee on Space Research (COSPAR). The IRI Working Group consists of a team of 43 experts who work on different aspects of the modeling problem. By charter IRI is a data-based (empirical) model that attempts to represent the combined ionospheric data base of ground and space measurements as accurate as possible. IRI provides monthly averages of the electron density, total electron content, electron temperature, ion temperature, ion composition (O+, H+, He+, N+, O2+, NO+, Cluster) and vertical ion drift (at the equator). If measured values are available the IRI profile can be updated with E and F peak densities and heights. IRI shortcomings, improvements, new additions, and applications are discussed during annual workshops. This talk will review the current status of the IRI project and describe the most recent version of the model, IRI-2000.

  16. Effectiveness of the International Phytosanitary Standard ISPM No. 15 on reducing wood borer infestation rates in wood packaging material entering the United States.

    PubMed

    Haack, Robert A; Britton, Kerry O; Brockerhoff, Eckehard G; Cavey, Joseph F; Garrett, Lynn J; Kimberley, Mark; Lowenstein, Frank; Nuding, Amelia; Olson, Lars J; Turner, James; Vasilaky, Kathryn N

    2014-01-01

    Numerous bark- and wood-infesting insects have been introduced to new countries by international trade where some have caused severe environmental and economic damage. Wood packaging material (WPM), such as pallets, is one of the high risk pathways for the introduction of wood pests. International recognition of this risk resulted in adoption of International Standards for Phytosanitary Measures No. 15 (ISPM15) in 2002, which provides treatment standards for WPM used in international trade. ISPM15 was originally developed by members of the International Plant Protection Convention to "practically eliminate" the risk of international transport of most bark and wood pests via WPM. The United States (US) implemented ISPM15 in three phases during 2005-2006. We compared pest interception rates of WPM inspected at US ports before and after US implementation of ISPM15 using the US Department of Agriculture AQIM (Agriculture Quarantine Inspection Monitoring) database. Analyses of records from 2003-2009 indicated that WPM infestation rates declined 36-52% following ISPM15 implementation, with results varying in statistical significance depending on the selected starting parameters. Power analyses of the AQIM data indicated there was at least a 95% chance of detecting a statistically significant reduction in infestation rates if they dropped by 90% post-ISPM15, but the probability fell as the impact of ISPM15 lessened. We discuss several factors that could have reduced the apparent impact of ISPM15 on lowering WPM infestation levels, and suggest ways that ISPM15 could be improved. The paucity of international interception data impeded our ability to conduct more thorough analyses of the impact of ISPM15, and demonstrates the need for well-planned sampling programs before and after implementation of major phytosanitary policies so that their effectiveness can be assessed. We also present summary data for bark- and wood-boring insects intercepted on WPM at US ports during 1984-2008.

  17. Effectiveness of the International Phytosanitary Standard ISPM No. 15 on reducing wood borer infestation rates in wood packaging material entering the United States.

    PubMed

    Haack, Robert A; Britton, Kerry O; Brockerhoff, Eckehard G; Cavey, Joseph F; Garrett, Lynn J; Kimberley, Mark; Lowenstein, Frank; Nuding, Amelia; Olson, Lars J; Turner, James; Vasilaky, Kathryn N

    2014-01-01

    Numerous bark- and wood-infesting insects have been introduced to new countries by international trade where some have caused severe environmental and economic damage. Wood packaging material (WPM), such as pallets, is one of the high risk pathways for the introduction of wood pests. International recognition of this risk resulted in adoption of International Standards for Phytosanitary Measures No. 15 (ISPM15) in 2002, which provides treatment standards for WPM used in international trade. ISPM15 was originally developed by members of the International Plant Protection Convention to "practically eliminate" the risk of international transport of most bark and wood pests via WPM. The United States (US) implemented ISPM15 in three phases during 2005-2006. We compared pest interception rates of WPM inspected at US ports before and after US implementation of ISPM15 using the US Department of Agriculture AQIM (Agriculture Quarantine Inspection Monitoring) database. Analyses of records from 2003-2009 indicated that WPM infestation rates declined 36-52% following ISPM15 implementation, with results varying in statistical significance depending on the selected starting parameters. Power analyses of the AQIM data indicated there was at least a 95% chance of detecting a statistically significant reduction in infestation rates if they dropped by 90% post-ISPM15, but the probability fell as the impact of ISPM15 lessened. We discuss several factors that could have reduced the apparent impact of ISPM15 on lowering WPM infestation levels, and suggest ways that ISPM15 could be improved. The paucity of international interception data impeded our ability to conduct more thorough analyses of the impact of ISPM15, and demonstrates the need for well-planned sampling programs before and after implementation of major phytosanitary policies so that their effectiveness can be assessed. We also present summary data for bark- and wood-boring insects intercepted on WPM at US ports during 1984

  18. Effectiveness of the International Phytosanitary Standard ISPM No. 15 on Reducing Wood Borer Infestation Rates in Wood Packaging Material Entering the United States

    PubMed Central

    Haack, Robert A.; Britton, Kerry O.; Brockerhoff, Eckehard G.; Cavey, Joseph F.; Garrett, Lynn J.; Kimberley, Mark; Lowenstein, Frank; Nuding, Amelia; Olson, Lars J.; Turner, James; Vasilaky, Kathryn N.

    2014-01-01

    Numerous bark- and wood-infesting insects have been introduced to new countries by international trade where some have caused severe environmental and economic damage. Wood packaging material (WPM), such as pallets, is one of the high risk pathways for the introduction of wood pests. International recognition of this risk resulted in adoption of International Standards for Phytosanitary Measures No. 15 (ISPM15) in 2002, which provides treatment standards for WPM used in international trade. ISPM15 was originally developed by members of the International Plant Protection Convention to “practically eliminate” the risk of international transport of most bark and wood pests via WPM. The United States (US) implemented ISPM15 in three phases during 2005–2006. We compared pest interception rates of WPM inspected at US ports before and after US implementation of ISPM15 using the US Department of Agriculture AQIM (Agriculture Quarantine Inspection Monitoring) database. Analyses of records from 2003–2009 indicated that WPM infestation rates declined 36–52% following ISPM15 implementation, with results varying in statistical significance depending on the selected starting parameters. Power analyses of the AQIM data indicated there was at least a 95% chance of detecting a statistically significant reduction in infestation rates if they dropped by 90% post-ISPM15, but the probability fell as the impact of ISPM15 lessened. We discuss several factors that could have reduced the apparent impact of ISPM15 on lowering WPM infestation levels, and suggest ways that ISPM15 could be improved. The paucity of international interception data impeded our ability to conduct more thorough analyses of the impact of ISPM15, and demonstrates the need for well-planned sampling programs before and after implementation of major phytosanitary policies so that their effectiveness can be assessed. We also present summary data for bark- and wood-boring insects intercepted on WPM at US ports

  19. Development of a proposed international standard for certification of aircraft to High Intensity Radiated Fields (HIRF)

    NASA Technical Reports Server (NTRS)

    Sargent, Noel B.

    1993-01-01

    Avionic systems performing critical functions in modern aircraft are potentially susceptible to the hazards of electromagnetic radiation from ground and airborne transmitters. The Federal Aviation Administration (FAA) requested that the Society of Automotive Engineers (SAE) coordinate the development of procedures and guidance material which can be used during the aircraft certification process to ensure adequate protection against high intensity radiated fields (HIRF). This paper addresses both the technical challenge of drafting a certification procedure and guidance standard as well as the management process used by the SAE subcommittee AE4R to converge a diverse range of opinions by its international membership in the shortest possible time.

  20. Quantitative Analysis of Polymer Additives with MALDI-TOF MS Using an Internal Standard Approach

    NASA Astrophysics Data System (ADS)

    Schwarzinger, Clemens; Gabriel, Stefan; Beißmann, Susanne; Buchberger, Wolfgang

    2012-06-01

    MALDI-TOF MS is used for the qualitative analysis of seven different polymer additives directly from the polymer without tedious sample pretreatment. Additionally, by using a solid sample preparation technique, which avoids the concentration gradient problems known to occur with dried droplets and by adding tetraphenylporphyrine as an internal standard to the matrix, it is possible to perform quantitative analysis of additives directly from the polymer sample. Calibration curves for Tinuvin 770, Tinuvin 622, Irganox 1024, Irganox 1010, Irgafos 168, and Chimassorb 944 are presented, showing coefficients of determination between 0.911 and 0.990.

  1. Quantitative analysis of polymer additives with MALDI-TOF MS using an internal standard approach.

    PubMed

    Schwarzinger, Clemens; Gabriel, Stefan; Beißmann, Susanne; Buchberger, Wolfgang

    2012-06-01

    MALDI-TOF MS is used for the qualitative analysis of seven different polymer additives directly from the polymer without tedious sample pretreatment. Additionally, by using a solid sample preparation technique, which avoids the concentration gradient problems known to occur with dried droplets and by adding tetraphenylporphyrine as an internal standard to the matrix, it is possible to perform quantitative analysis of additives directly from the polymer sample. Calibration curves for Tinuvin 770, Tinuvin 622, Irganox 1024, Irganox 1010, Irgafos 168, and Chimassorb 944 are presented, showing coefficients of determination between 0.911 and 0.990.

  2. Methodological aspects of clinical trials in tinnitus: A proposal for an international standard

    PubMed Central

    Landgrebe, Michael; Azevedo, Andréia; Baguley, David; Bauer, Carol; Cacace, Anthony; Coelho, Claudia; Dornhoffer, John; Figueiredo, Ricardo; Flor, Herta; Hajak, Goeran; van de Heyning, Paul; Hiller, Wolfgang; Khedr, Eman; Kleinjung, Tobias; Koller, Michael; Lainez, Jose Miguel; Londero, Alain; Martin, William H.; Mennemeier, Mark; Piccirillo, Jay; De Ridder, Dirk; Rupprecht, Rainer; Searchfield, Grant; Vanneste, Sven; Zeman, Florian; Langguth, Berthold

    2013-01-01

    Chronic tinnitus is a common condition with a high burden of disease. While many different treatments are used in clinical practice, the evidence for the efficacy of these treatments is low and the variance of treatment response between individuals is high. This is most likely due to the great heterogeneity of tinnitus with respect to clinical features as well as underlying pathophysiological mechanisms. There is a clear need to find effective treatment options in tinnitus, however, clinical trials differ substantially with respect to methodological quality and design. Consequently, the conclusions that can be derived from these studies are limited and jeopardize comparison between studies. Here, we discuss our view of the most important aspects of trial design in clinical studies in tinnitus and make suggestions for an international methodological standard in tinnitus trials. We hope that the proposed methodological standard will stimulate scientific discussion and will help to improve the quality of trials in tinnitus. PMID:22789414

  3. The current state of the international standard for exchange of optical data in electronic form

    NASA Astrophysics Data System (ADS)

    Wormell, Prudence M. J. H.

    2006-06-01

    The International Organization for Standardization (ISO) is developing a standard for the exchange of optical data in electronic form between different design programs. In order that the data be completely unambiguous an on-line Properties Dictionary is also being established, when finished this should be available to subscribers to ISO and will enable optical designers and manufacturing industry to access information accurately and transfer this information without manual intervention, across many boundaries. The Neutral Optical Data Interchange Format (NODIF) will use this dictionary to define the optical data that can be passed between to any CAD programs that are STEP compliant. NODIF is of concern to software developers, the Properties Dictionary is of concern to manufacturers.

  4. Double standards and the international trade of pesticides: the Brazilian case.

    PubMed

    Porto, Marcelo Firpo; Milanez, Bruno; Soares, Wagner Lopes; Meyer, Armando

    2010-01-01

    Despite bans on certain pesticides and their replacement by others considered less hazardous, the widespread use of these substances in agriculture continues to threaten the environment and the health of millions of people. This article discusses the current double standard in the international trade of pesticides and focuses on Brazil, one of the main users of pesticides in the world, analyzing the trends in foreign trade (imports and exports) of selected pesticides as a function of changes in legislation in the United States, the European Union, and Brazil from 1989 to 2006. We applied time line analysis to eight organochlorines already banned in Brazil and conducted a case-by-case qualitative and quantitative analysis of nine other pesticides. The results indicate the existence of double standards, as demonstrated by the continued exports to Brazil of some pesticides banned in the United States and Europe. PMID:20166316

  5. [Simultaneous determination of 11 mycotoxins in malt by isotope internal standard-UPLC-MS/MS].

    PubMed

    Wang, Sha; Kong, Wei-jun; Yang, Mei-hua

    2016-01-01

    A suitable ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) method was developed for the determination of 11 mycotoxins with isotope internal standard in malt. The mycotoxins in malt were extracted and purified by one-step ultrasonic extraction procedure using acetonitrile/water/acetic acid (80 : 19 : 1), and then detected and confirmed by UPLC-MS/MS, and quantified by isotope labeled AFB1 ([13C17]-AFB1) and ZEN ([13C18]-ZEN) internal standards. Rapid separation of the 11 mycotoxins was successfully achieved on a Phenomenex Kinetex C18 column (100 mm x 2.1 mm, 2.6 μm) with gradient elution using the mobile phase of methanol containing 0.1% formic acid and 2 mmol x L(-1) ammonium acetate in water. Simultaneous acquisition was performed in multiple reaction monitoring (MRM) mode with electrospray ionization (ESI) source operated in both positive and negative ionization modes. The established method provided a good linearity for the 11 mycotoxins within their respective linear ranges with correlation coefficients all higher than 0.999 1. The average recoveries ranged from 75.0% to 117.0% with relative standard deviations (RSDs) below 5.1%. The limits of detection (LODs) and quantitation (LOQs) ranged from 0.05 to 30 μg x kg(-1) and 0.15 to 87.5 μg x kg(-1), respectively, which were below the maximum residue levels (MRLs) set by the European Union. Twenty malt samples were analyzed and nine samples were detected with mycotoxins, which were confirmed according to the same fragment ions found in positive samples and the standards at the same retention time. This study has demonstrated that the one-step extraction procedure of mycotoxins from complex matrices coupled to UPLC-MS/MS method is simple, quick, accurate and sensitive for quantitative and qualitative analysis of multiple mycotoxins in malt. PMID:27405171

  6. [Simultaneous determination of 11 mycotoxins in malt by isotope internal standard-UPLC-MS/MS].

    PubMed

    Wang, Sha; Kong, Wei-jun; Yang, Mei-hua

    2016-01-01

    A suitable ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) method was developed for the determination of 11 mycotoxins with isotope internal standard in malt. The mycotoxins in malt were extracted and purified by one-step ultrasonic extraction procedure using acetonitrile/water/acetic acid (80 : 19 : 1), and then detected and confirmed by UPLC-MS/MS, and quantified by isotope labeled AFB1 ([13C17]-AFB1) and ZEN ([13C18]-ZEN) internal standards. Rapid separation of the 11 mycotoxins was successfully achieved on a Phenomenex Kinetex C18 column (100 mm x 2.1 mm, 2.6 μm) with gradient elution using the mobile phase of methanol containing 0.1% formic acid and 2 mmol x L(-1) ammonium acetate in water. Simultaneous acquisition was performed in multiple reaction monitoring (MRM) mode with electrospray ionization (ESI) source operated in both positive and negative ionization modes. The established method provided a good linearity for the 11 mycotoxins within their respective linear ranges with correlation coefficients all higher than 0.999 1. The average recoveries ranged from 75.0% to 117.0% with relative standard deviations (RSDs) below 5.1%. The limits of detection (LODs) and quantitation (LOQs) ranged from 0.05 to 30 μg x kg(-1) and 0.15 to 87.5 μg x kg(-1), respectively, which were below the maximum residue levels (MRLs) set by the European Union. Twenty malt samples were analyzed and nine samples were detected with mycotoxins, which were confirmed according to the same fragment ions found in positive samples and the standards at the same retention time. This study has demonstrated that the one-step extraction procedure of mycotoxins from complex matrices coupled to UPLC-MS/MS method is simple, quick, accurate and sensitive for quantitative and qualitative analysis of multiple mycotoxins in malt.

  7. International Society for the Advancement of Cytometry Cell Sorter Biosafety Standards

    PubMed Central

    Holmes, Kevin L.; Fontes, Benjamin; Hogarth, Philip; Konz, Richard; Monard, Simon; Pletcher, Charles H.; Wadley, Robert B.; Schmid, Ingrid; Perfetto, Stephen P.

    2014-01-01

    Flow cytometric cell sorting of biological specimens has become prevalent in basic and clinical research laboratories. These specimens may contain known or unknown infectious agents, necessitating precautions to protect instrument operators and the environment from biohazards arising from the use of sorters. To this end the International Society of Analytical Cytology (ISAC) was proactive in establishing biosafety guidelines in 1997 (Schmid et al., Cytometry 1997;28:99–117) and subsequently published revised biosafety standards for cell sorting of unfixed samples in 2007 (Schmid et al., Cytometry Part A J Int Soc Anal Cytol 2007;71A:414–437). Since their publication, these documents have become recognized worldwide as the standard of practice and safety precautions for laboratories performing cell sorting experiments. However, the field of cytometry has progressed since 2007, and the document requires an update. The new Standards provides guidance: (1) for laboratory design for cell sorter laboratories; (2) for the creation of laboratory or instrument specific Standard Operating Procedures (SOP); and (3) on procedures for the safe operation of cell sorters, including personal protective equipment (PPE) and validation of aerosol containment. PMID:24634405

  8. Stable isotope coded derivatizing reagents as internal standards in metabolite profiling.

    PubMed

    Bruheim, Per; Kvitvang, Hans Fredrik Nyvold; Villas-Boas, Silas G

    2013-06-28

    Gas chromatography (GC) and liquid chromatography (LC) coupled to mass spectrometric (MS) detection have become the two main techniques for the analysis of metabolite pools (i.e. Metabolomics). These technologies are especially suited for Metabolite Profiling analysis of various metabolite groups due to high separation capabilities of the chromatographs and high sensitivity of the mass analysers. The trend in quantitative Metabolite Profiling is to add more metabolites and metabolite groups in a single method. This should not be done by compromising the analytical precision. Mass spectrometric detection comes with certain limitations, especially in the quantitative aspects as standards are needed for conversion of ion abundance to concentration and ionization efficiencies are directly dependent on eluent conditions. This calls for novel strategies to counteract all variables that can influence the quantitative precision. Usually, internal standards are used to correct any technical variation. For quantitation of single or just a few analytes this can be executed with spiking isotopically labeled standards. However, for more comprehensive analytical tasks, e.g. profiling tens or hundreds of analytes simultaneously, this strategy becomes expensive and in many cases isotopically labeled standards are not available. An alternative is to introduce a derivatizing step where the sample is derivatized with naturally labeled reagent, while a standard solution is separately derivatized with isotopically labeled reagent and spiked into the sample solution prior to analysis. This strategy, named isotope coded derivatization - ICD, is attractive in the emerging field of quantitative Metabolite Profiling where current protocols can easily comprise over hundred metabolites. This review provides an overview of isotopically labeled derivatizing reagents that have been developed for important metabolite groups with the aim to improve analytical performance and precision.

  9. Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard.

    PubMed

    Pirman, David A; Reich, Richard F; Kiss, András; Heeren, Ron M A; Yost, Richard A

    2013-01-15

    Mass spectrometric imaging (MSI) is an analytical technique used to determine the distribution of individual analytes within a given sample. A wide array of analytes and samples can be investigated by MSI, including drug distribution in rats, lipid analysis from brain tissue, protein differentiation in tumors, and plant metabolite distributions. Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique capable of desorbing and ionizing a large range of compounds, and it is the most common ionization source used in MSI. MALDI mass spectrometry (MS) is generally considered to be a qualitative analytical technique because of significant ion-signal variability. Consequently, MSI is also thought to be a qualitative technique because of the quantitative limitations of MALDI coupled with the homogeneity of tissue sections inherent in an MSI experiment. Thus, conclusions based on MS images are often limited by the inability to correlate ion signal increases with actual concentration increases. Here, we report a quantitative MSI method for the analysis of cocaine (COC) from brain tissue using a deuterated internal standard (COC-d(3)) combined with wide-isolation MS/MS for analysis of the tissue extracts with scan-by-scan COC-to-COC-d(3) normalization. This resulted in significant improvements in signal reproducibility and calibration curve linearity. Quantitative results from the MSI experiments were compared with quantitative results from liquid chromatography (LC)-MS/MS results from brain tissue extracts. Two different quantitative MSI techniques (standard addition and external calibration) produced quantitative results comparable to LC-MS/MS data. Tissue extracts were also analyzed by MALDI wide-isolation MS/MS, and quantitative results were nearly identical to those from LC-MS/MS. These results clearly demonstrate the necessity for an internal standard for quantitative MSI experiments. PMID:23214490

  10. Utilizing Internal Standard Responses to Assess Risk on Reporting Bioanalytical Results from Hemolyzed Samples.

    PubMed

    Fung, Eliza N; Aubry, Anne-Françoise; Allentoff, Alban; Ji, Qin C

    2015-09-01

    Bioanalytical analysis of toxicokinetic and pharmacokinetic samples is an integral part of small molecule drugs development and liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been the technique of choice. One important consideration is the matrix effect, in which ionization of the analytes of interest is affected by the presence of co-eluting interfering components present in the sample matrix. Hemolysis, which results in additional endogenous components being released from the lysed red blood cells, may cause additional matrix interferences. The effects of the degree of hemolysis on the accuracy and precision of the method and the reported sample concentrations from hemolyzed study samples have drawn increasing attention in recent years, especially in cases where the sample concentrations are critical for pharmacokinetic calculation. Currently, there is no established procedure to objectively assess the risk of reporting potentially inaccurate bioanalytical results from hemolyzed study samples. In this work, we evaluated the effect of different degrees of hemolysis on the internal standard peak area, accuracy, and precision of the analyses of BMS-906024 and its metabolite, BMS-911557, in human plasma by LC-MS/MS. In addition, we proposed the strategy of using the peak area of the stable isotope-labeled internal standard (SIL-IS) from the LC-MS/MS measurement as the surrogate marker for risk assessment. Samples with peak areas outside of the pre-defined acceptance criteria, e.g., less than 50% or more than 150% of the average IS response in study samples, plasma standards, and QC samples when SIL-IS is used, are flagged out for further investigation. PMID:25975617

  11. Overview and comparative study of GPR international standards and guidelines - COST Action TU1208

    NASA Astrophysics Data System (ADS)

    Pajewski, Lara; Marciniak, Marian; Benedetto, Andrea; Tosti, Fabio

    2016-04-01

    Ground Penetrating Radar (GPR) can be effectively used for non-destructive testing of composite structures and diagnostics affecting the whole life-cycle of civil engineering works. Nevertheless, few recognised international standards exist in this field and inhomogeneous recommendations are present in different countries. Moreover, the levels of knowledge, awareness and experience regarding the use of GPR in civil engineering vary strongly across different European areas. The COST Action TU1208 is working hard on leveraging these differences, by sharing and disseminating knowledge and experience, as well as by developing guidelines and protocols for a safe and effective use of GPR in civil engineering. GPR users need to know which is the best way to conduct GPR measurements and what the quality level for the results should be. The TU1208 guidelines will ensure a higher efficiency and quality of GPR services and they will constitute a scientific basis for the introduction of European Standards on the application of GPR in civil engineering. The aim of this contribution is to present an in-depth overview and critical analysis of the existing GPR international and national standards and guidelines. The main documents considered in our work are listed and briefly described in the following. Three standards are provided by the American Society for Testing and Materials (ASTM), to guide the GPR use for subsurface investigation, evaluation of asphalt-covered concrete bridge decks, and determination of pavement-layer thickness: 1. ASTM D6432-11, Standard Guide for Using the Surface Ground Penetrating Radar Method for Subsurface Investigation, ASTM International, West Conshohocken, PA, 2011, www.astm.org, DOI: 10.1520/D6432-11. 2. ASTM D6087-08, Standard Test Method for Evaluating Asphalt-Covered Concrete Bridge Decks Using Ground Penetrating Radar, ASTM International, West Conshohocken, PA, 2008, www.astm.org, DOI: 10.1520/D6087-08. 3. ASTM D4748-10, Standard Test Method

  12. Standardization of negative controls in diagnostic immunohistochemistry: recommendations from the international ad hoc expert panel.

    PubMed

    Torlakovic, Emina E; Francis, Glenn; Garratt, John; Gilks, Blake; Hyjek, Elizabeth; Ibrahim, Merdol; Miller, Rodney; Nielsen, Søren; Petcu, Eugen B; Swanson, Paul E; Taylor, Clive R; Vyberg, Mogens

    2014-04-01

    Standardization of controls, both positive and negative controls, is needed for diagnostic immunohistochemistry (dIHC). The use of IHC-negative controls, irrespective of type, although well established, is not standardized. As such, the relevance and applicability of negative controls continues to challenge both pathologists and laboratory budgets. Despite the clear theoretical notion that appropriate controls serve to demonstrate the sensitivity and specificity of the dIHC test, it remains unclear which types of positive and negative controls are applicable and/or useful in day-to-day clinical practice. There is a perceived need to provide "best practice recommendations" for the use of negative controls. This perception is driven not only by logistics and cost issues, but also by increased pressure for accurate IHC testing, especially when IHC is performed for predictive markers, the number of which is rising as personalized medicine continues to develop. Herein, an international ad hoc expert panel reviews classification of negative controls relevant to clinical practice, proposes standard terminology for negative controls, considers the total evidence of IHC specificity that is available to pathologists, and develops a set of recommendations for the use of negative controls in dIHC based on "fit-for-use" principles.

  13. Antibody responses to allergen Lol pIV are suppressed following adoptive transfer of B lymphocytes from the internal image anti-idiotypic antibody-treated mice.

    PubMed

    Zhou, E M; Kisil, F T

    1995-10-01

    An internal image anti-idiotypic antibody, designated B1/1, was generated against an idiotope (Id91) of the monoclonal antibody (mAb91) specific for Lol pIV. The administration of B1/1 in PBS, at doses ranging from 100 ng to 100 micrograms/mouse, to syngeneic Balb/c mice resulted in the suppression of the formation of anti-Lol pIV antibodies that possessed the Id91. Spleen cells obtained from the mice 2 weeks after the treatment with B1/1 (25 micrograms/mouse) were adoptively transferred intravenously into the syngeneic recipients which were challenged intraperitoneally with Lol pIV in alum 2 hr after the transfer. The recipients were boosted with Lol pIV 14 days later. It was demonstrated that the transfer of splenic B cells (but not of T cells) from B1/1-treated donors induced a significant suppression of not only the level of IgE and IgG antibodies to Lol pIV, but also the level of antibodies possessing the Id91. Treatment of the B cells with mAb91 plus complement abrogated their ability to transfer the suppression. This study indicates that the treatment with the anti-Id B1/1 generated B cells that were characterized, serologically, as possessing the anti-Id-like antibodies on their surface and were responsible for transferring the suppression of the formation of antibodies to allergen Lol pIV and the expression of Id91.

  14. International Comparison of FTIR measurements traceable to HITRAN and Gravimetrically prepared Gas Standards

    NASA Astrophysics Data System (ADS)

    Edgar, F.; Joële, V.; Philippe, M.; Faraz, I.; Robert, W.

    2009-12-01

    An international comparison is being organised to compare measurement results of gas concentration that are traceable to the HITRAN database with SI traceable values based on gravimetrically prepared gas standards. The results of the comparison will allow potential biases for specific gas species in the HITRAN database to be identified. The comparison is being performed on nitrogen dioxide (NO2) but the developed methodology is applicable to the majority of gas species in the HITRAN database. There is a high international priority attached to activities which reduce NOx in the atmosphere. The current level of permitted emissions is typically between 50 μmol/mol and 100 μmol/mol, but lower values are expected in the future. Currently, ambient air quality monitoring regulations also require the measurement of NOx mole fractions of 0.2 μmol/mol. To determine accurately the NO2 mole fraction at ambient levels high quality primary gas references are desirable. However, since NO2 is a reactive gas, stability problems in the gas standards below mole fractions of 100 μmol/mol, and particularly below 10 μmol/mol, has been observed and studied at the Bureau International des Poids et Mesures during the last years. An international comparison of NO2 measurement capabilities between National Metrology Institutes, coordinated by the Bureau International des Poids et Mesures, was initiated in June 2009. The comparison consists in two main protocols, the protocol CCQM-K74 and the protocol CCQM-P110. The procedure CCQM-K74 comparison is designed to evaluate the level of comparability of the laboratories’ measurement capabilities for NO2 at a nominal mole fraction of 10 μmol/mol based on their own measurement capabilities. The CCQM-P110 protocol, open only to laboratories maintaining Fourier Transform Infrared Spectroscopy facilities, aims to evaluate the level of comparability of laboratories’ NO2 measurement capabilities based on FTIR spectroscopy traceable to primary

  15. Overview and comparative study of GPR international standards and guidelines - COST Action TU1208

    NASA Astrophysics Data System (ADS)

    Pajewski, Lara; Marciniak, Marian; Benedetto, Andrea; Tosti, Fabio

    2016-04-01

    Ground Penetrating Radar (GPR) can be effectively used for non-destructive testing of composite structures and diagnostics affecting the whole life-cycle of civil engineering works. Nevertheless, few recognised international standards exist in this field and inhomogeneous recommendations are present in different countries. Moreover, the levels of knowledge, awareness and experience regarding the use of GPR in civil engineering vary strongly across different European areas. The COST Action TU1208 is working hard on leveraging these differences, by sharing and disseminating knowledge and experience, as well as by developing guidelines and protocols for a safe and effective use of GPR in civil engineering. GPR users need to know which is the best way to conduct GPR measurements and what the quality level for the results should be. The TU1208 guidelines will ensure a higher efficiency and quality of GPR services and they will constitute a scientific basis for the introduction of European Standards on the application of GPR in civil engineering. The aim of this contribution is to present an in-depth overview and critical analysis of the existing GPR international and national standards and guidelines. The main documents considered in our work are listed and briefly described in the following. Three standards are provided by the American Society for Testing and Materials (ASTM), to guide the GPR use for subsurface investigation, evaluation of asphalt-covered concrete bridge decks, and determination of pavement-layer thickness: 1. ASTM D6432-11, Standard Guide for Using the Surface Ground Penetrating Radar Method for Subsurface Investigation, ASTM International, West Conshohocken, PA, 2011, www.astm.org, DOI: 10.1520/D6432-11. 2. ASTM D6087-08, Standard Test Method for Evaluating Asphalt-Covered Concrete Bridge Decks Using Ground Penetrating Radar, ASTM International, West Conshohocken, PA, 2008, www.astm.org, DOI: 10.1520/D6087-08. 3. ASTM D4748-10, Standard Test Method

  16. Benefits of voluntary industry standards: The triumph of experience over regulation

    SciTech Connect

    O`Leary, J.T.

    1996-12-31

    Voluntary international standards for mining machinery may gradually replace many national regulations. The days of establishing voluntary standards nation by nation, inhibiting the important flow of international trade, could be numbered. This does not mean that nations will cease domestic regulatory activities within their boundaries, but rulemaking will pay considerable attention to voluntary international standards and will likely strive for compatibility with voluntary international standards. International standards setting bodies are developing standards for machine safety. When these standards are complete and adopted, some nations will require machinery to comport with them. International commerce in products that do not conform to these voluntary international standards may be discouraged.

  17. Taking the Lead in Science Education: Forging Next-Generation Science Standards. International Science Benchmarking Report. Appendix

    ERIC Educational Resources Information Center

    Achieve, Inc., 2010

    2010-01-01

    This appendix accompanies the report "Taking the Lead in Science Education: Forging Next-Generation Science Standards. International Science Benchmarking Report," a study conducted by Achieve to compare the science standards of 10 countries. This appendix includes the following: (1) PISA and TIMSS Assessment Rankings; (2) Courses and Levels…

  18. Reproducible vapor-time profiles using solid-phase microextraction with an externally sampled internal standard.

    PubMed

    MacCrehan, William; Moore, Stephanie; Schantz, Michele

    2012-06-29

    Determination of the dynamic nature of vapor/odor release has application in a wide variety of systems. This study applies automated solid-phase microextraction (SPME) utilizing an externally sampled internal standard (ESIS) to determine the vapor-time profile of odor delivery devices for three classes of explosive compounds. The profiles of delivery systems for target odorants 2,4-dinitrotoluene (2,4-DNT), 2-ethyl-1-hexanol (2-EH), and triacetone triperoxide (TATP) as canine training aids were compared over a period of 70 h. Strategies for evaluating the vapor-time profile of components with widely differing volatility are considered. An approach to quantifying the vapor concentration is described. The differences in the vapor-time profiles are examined and suggestions for selecting the best representative odor delivery technique are outlined. PMID:22633864

  19. Increasing Allele Detection by Altering the Quantity of Internal Lane Standard.

    PubMed

    Esparza, Jessica M; Michalik, Monnie; Dukes, Mary Jones; Wojtkiewicz, Patrick

    2016-01-01

    Electrokinetic injection (EI) is the primary method used in forensic laboratories to load amplified PCR product in capillary electrophoresis for short tandem repeat (STR) fragment separation. Because all samples subjected to capillary electrophoresis use internal lane standard (ILS), this study investigated the consequence of varying the volume of ILS and its effects on allele peak heights and number of alleles detected. Results demonstrated that when the volume of ILS is reduced, the average peak height and number of alleles increased, thereby increasing the sensitivity of the detection method. Sizing anomalies were observed; however, they did not adversely affect accuracy and precision. The method developed in this study offers a simple and universal procedure to increase the alleles detected in forensic STR analysis. Reducing the volume of ILS to achieve greater sensitivity is applicable to all STR amplification kits and capillary electrophoresis instruments currently used in forensic DNA analysis. PMID:26390320

  20. Heteromer score-using internal standards to assess the quality of proteomic data.

    PubMed

    Rogowska-Wrzesinska, Adelina; Wrzesinski, Krzysztof; Fey, Stephen J

    2014-05-01

    In the cell, the majority of proteins exist in complexes. Most of these complexes have a constant stoichiometry and thus can be used as internal standards. In this rapid communication, we show that it is possible to calculate a correlation coefficient that reflects the reproducibility of the analytical approach used. The abundance of one subunit in a heterodimer is plotted against the abundance of the other, and this is repeated for all subunits in all heteromers found in the data set. The correlation coefficient obtained (the "heteromer score") is a new bioinformatic tool that is independent of the method used to collect the data, requires no special sample preparation and can be used retrospectively on old datasets. It can be used for quality control, to indicate when a change becomes significant or identify complexes whose stoichiometry has been perturbed during the experiment.

  1. An International Standard Set of Patient-Centered Outcome Measures After Stroke

    PubMed Central

    Salinas, Joel; Sprinkhuizen, Sara M.; Ackerson, Teri; Bernhardt, Julie; Davie, Charlie; George, Mary G.; Gething, Stephanie; Kelly, Adam G.; Lindsay, Patrice; Liu, Liping; Martins, Sheila C.O.; Morgan, Louise; Norrving, Bo; Ribbers, Gerard M.; Silver, Frank L.; Smith, Eric E.; Williams, Linda S.

    2016-01-01

    Background and Purpose— Value-based health care aims to bring together patients and health systems to maximize the ratio of quality over cost. To enable assessment of healthcare value in stroke management, an international standard set of patient-centered stroke outcome measures was defined for use in a variety of healthcare settings. Methods— A modified Delphi process was implemented with an international expert panel representing patients, advocates, and clinical specialists in stroke outcomes, stroke registers, global health, epidemiology, and rehabilitation to reach consensus on the preferred outcome measures, included populations, and baseline risk adjustment variables. Results— Patients presenting to a hospital with ischemic stroke or intracerebral hemorrhage were selected as the target population for these recommendations, with the inclusion of transient ischemic attacks optional. Outcome categories recommended for assessment were survival and disease control, acute complications, and patient-reported outcomes. Patient-reported outcomes proposed for assessment at 90 days were pain, mood, feeding, selfcare, mobility, communication, cognitive functioning, social participation, ability to return to usual activities, and health-related quality of life, with mobility, feeding, selfcare, and communication also collected at discharge. One instrument was able to collect most patient-reported subdomains (9/16, 56%). Minimum data collection for risk adjustment included patient demographics, premorbid functioning, stroke type and severity, vascular and systemic risk factors, and specific treatment/care-related factors. Conclusions— A consensus stroke measure Standard Set was developed as a simple, pragmatic method to increase the value of stroke care. The set should be validated in practice when used for monitoring and comparisons across different care settings. PMID:26604251

  2. 40 CFR 60.4203 - How long must my engines meet the emission standards if I am a stationary CI internal combustion...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... emission standards if I am a stationary CI internal combustion engine manufacturer? 60.4203 Section 60.4203... standards if I am a stationary CI internal combustion engine manufacturer? Engines manufactured by stationary CI internal combustion engine manufacturers must meet the emission standards as required in §§...

  3. 40 CFR 60.4203 - How long must my engines meet the emission standards if I am a stationary CI internal combustion...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... emission standards if I am a stationary CI internal combustion engine manufacturer? 60.4203 Section 60.4203... standards if I am a stationary CI internal combustion engine manufacturer? Engines manufactured by stationary CI internal combustion engine manufacturers must meet the emission standards as required in §§...

  4. A novel reductive amination method with isotopic formaldehydes for the preparation of internal standard and standards for determining organosulfur compounds in garlic.

    PubMed

    Tsai, De-Cheng; Liu, Meng-Chieh; Lin, Yi-Reng; Huang, Mei-Fang; Liang, Shih-Shin

    2016-04-15

    Garlic (Allium sativum) is a long-cultivated plant that is widely utilized in cooking and has been employed as a medicine for over 4000 years. In this study, we fabricated standards and internal standards (ISs) for absolute quantification via reductive amination with isotopic formaldehydes. Garlic has four abundant organosulfur compounds (OSCs): S-allylcysteine, S-allylcysteinine sulfoxide, S-methylcysteine, and S-ethylcysteine are abundant in garlic. OSCs with primary amine groups were reacted with isotopic formaldehydes to synthesize ISs and standards. Cooked and uncooked garlic samples were compared, and we utilized tandem mass spectrometry equipped with a selective reaction monitoring technique to absolutely quantify the four organosulfur compounds.

  5. Fast high-throughput method for the determination of acidity constants by capillary electrophoresis. II. Acidic internal standards.

    PubMed

    Cabot, Joan Marc; Fuguet, Elisabet; Ràfols, Clara; Rosés, Martí

    2010-12-24

    A fast method for the determination of acidity constants by CZE has been recently developed. This method is based on the use of an internal standard of pK(a) similar to that of the analyte. In this paper we establish the reference pK(a) values of a set of 24 monoprotic neutral acids of varied structure that we propose as internal standards. These compounds cover the most usual working pH range in CZE and facilitate the selection of adequate internal standards for a given determination. The reference pK(a) values of the acids have been established by the own internal standard method, i.e. from the mobility differences between different acids of similar pK(a) in the same pH buffers. The determined pK(a) values have been contrasted to the literature pK(a) values and confirmed by determination of the pK(a) values of some acids of the set by the classical CE method. Some systematic deviations of mobilities have been observed in NaOH buffer in reference to the other used buffers, overcoming the use of NaOH in the classical CE method. However, the deviations affect in a similar degree to the test compounds and internal standards allowing thus, the use of NaOH buffer in the internal standard method. This fact demonstrates the better performance of the internal standard method over the classical method to correct mobility deviations, which together with its fastness makes it an interesting method for the routine determination of accurate pK(a) values of new pharmaceutical drugs and drug precursors.

  6. Establishment of replacement International Standard 13/132 for human antibodies to Toxoplasma gondii.

    PubMed

    Rijpkema, Sjoerd; Hockley, Jason; Rigsby, Peter; Guy, Edward C

    2016-09-01

    Sixteen laboratories carried out a collaborative study to validate 13/132 as a replacement International Standard (IS) for TOXM (3rd IS for anti-Toxoplasma Serum, Human, 1000 IU). 13/132 is a freeze dried preparation of pooled human plasma from six donors who experienced a recent Toxoplasma gondii infection. The potency of 13/132 was compared to TOXM and 01/600 (1st IS for anti-Toxoplasma IgG, Human, 20 IU). Samples were tested for IgA, IgG, IgG avidity and IgM in agglutination assays; enzyme linked immunosorbent assays (ELISA), enzyme linked fluorescent assays, immunoblots, immunofluorescence assays and the Sabin-Feldman dye test for Ig. 13/132 was strongly positive for Ig, IgA, IgG and IgM and the reproducibility was very good. 13/132 contains high levels of anti-Toxoplasma Ig, IgG and IgM and its potency falls between TOXM and 01/600. The avidity of IgG was found to be low, similar to the avidity of IgG from TOXM. 13/132 was established by the Expert Committee on Biological Standardization as the 4th IS for Antibodies, Human, to T. gondii with an assigned unitage of 160 IU per ampoule for Ig by dye test and 263 U per ampoule for IgG by ELISA. PMID:27378430

  7. IEEE802.15.6 NB portable BAN clinic and M2M international standardization.

    PubMed

    Kuroda, Masahiro; Nohara, Yasunobu

    2013-01-01

    The increase of non communicable diseases (NCDs) will change the direction of health services to emphasize the role of preventive medicine in healthcare services. The first short-range medical body are network (BAN) standard IEEE802.15.6 is expected to be used for secure and user-friendly sensor devices for portable medical equipment. A BAN is an enabler for uploading medical data to a backend system for remote diagnoses and treatment. Machine-to-Machine (M2M) infrastructure is also a key technology for providing flexible and affordable services extending electronic health record (EHR) systems. This paper proposes a BAN-based portable clinic that collects health-check data from user-friendly medical devices and sensors and sends the data to a local backend server, and it evaluates the clinic in fields of actual usage. We discuss issues experienced from actual deployment of the system and focus on integrating it into upcoming healthcare M2M infrastructure to achieve affordable and dependable clinic services. We explain the components and workflow of the clinic and the system model. The system is set up at a temporary health center and has a network link to a remote medical help center. The paper concludes with our plan to introduce our system to contribute to internationally standardized preventive medicine. PMID:24110023

  8. Qualification of Programmable Electronic System (PES) equipment based on international nuclear I and C standards

    SciTech Connect

    De Grosbois, J.; Hepburn, G. A.; Olmstead, R.; Goble, W.; Kumar, V.

    2006-07-01

    Nuclear power plants (NPPs) are increasingly faced with the challenge of qualifying procured equipment, sub-components, and systems that contain digital programmed electronics for use in safety-related applications. Referred to as a 'programmable electronic system' (PES), such equipment typically contains both complex logic that is vulnerable to systematic design faults, and low voltage electronics hardware that is subject to random faults. Procured PES products or components are often only commercial grade, yet can offer reliable cost effective alternatives to custom-designed or nuclear qualified equipment, provided they can be shown to meet the quality assurance, functional safety, environmental, and reliability requirements of a particular application. The process of confirming this is referred to as application-specific product qualification (ASPQ) and can be challenging and costly. This paper provides an overview of an approach that has been developed at Atomic Energy Canada Limited (AECL) and successfully applied to PES equipment intended for use in domestic Candu R 6 nuclear power plants and special purpose reactors at Chalk River Laboratories. The approach has evolved over the past decade and has recently been adapted to be consistent with, and take advantage of new standards that are applicable to nuclear safety-related I and C systems. Also discussed are how recognized third-party safety-certifications of PES equipment to International Electrotechnical Commission (IEC) standards, and the assessment methods employed, may be used to reduce ASPQ effort. (authors)

  9. IEEE802.15.6 NB portable BAN clinic and M2M international standardization.

    PubMed

    Kuroda, Masahiro; Nohara, Yasunobu

    2013-01-01

    The increase of non communicable diseases (NCDs) will change the direction of health services to emphasize the role of preventive medicine in healthcare services. The first short-range medical body are network (BAN) standard IEEE802.15.6 is expected to be used for secure and user-friendly sensor devices for portable medical equipment. A BAN is an enabler for uploading medical data to a backend system for remote diagnoses and treatment. Machine-to-Machine (M2M) infrastructure is also a key technology for providing flexible and affordable services extending electronic health record (EHR) systems. This paper proposes a BAN-based portable clinic that collects health-check data from user-friendly medical devices and sensors and sends the data to a local backend server, and it evaluates the clinic in fields of actual usage. We discuss issues experienced from actual deployment of the system and focus on integrating it into upcoming healthcare M2M infrastructure to achieve affordable and dependable clinic services. We explain the components and workflow of the clinic and the system model. The system is set up at a temporary health center and has a network link to a remote medical help center. The paper concludes with our plan to introduce our system to contribute to internationally standardized preventive medicine.

  10. Acting Globally: Potential Carbon Emissions Mitigation Impacts from an International Standards and Labelling Program

    SciTech Connect

    McNeil, Michael A; Letschert, Virginie E.; de la Rue du Can, Stephane; Egan, Christine

    2009-05-29

    This paper presents an analysis of the potential impacts of an international initiative designed to support and promote the development and implementation of appliances standards and labelling programs throughout the world. As part of previous research efforts, LBNL developed the Bottom Up Energy Analysis System (BUENAS), an analysis framework that estimates impact potentials of energy efficiency policies on a global scale. In this paper, we apply this framework to an initiative that would result in the successful implementation of programs focused on high priority regions and product types, thus evaluating the potential impacts of such an initiative in terms of electricity savings and carbon mitigation in 2030. In order to model the likely parameters of such a program, we limit impacts to a five year period starting in 2009, but assume that the first 5 years of a program will result in implementation of 'best practice' minimum efficiency performance standards by 2014. The 'high priority' regions considered are: Brazil, China, the European Union,India, Mexico and the United States. The products considered are: refrigerators, air conditioners, lighting (both fluorescent and incandescent), standby power (for consumer electronics) and televisions in the residential sector, and air conditioning and lighting in commercial buildings. In 2020, these regions and enduses account for about 37percent of global residential electricity and 29percent of electricity in commercial buildings. We find that 850Mt of CO2 could be saved in buildings by 2030 compared to the baseline forecast.

  11. Novel Instrument for Automated pK(a) Determination by Internal Standard Capillary Electrophoresis.

    PubMed

    Cabot, Joan M; Fuguet, Elisabet; Rosés, Martí; Smejkal, Petr; Breadmore, Michael C

    2015-06-16

    The internal standard capillary electrophoresis method (IS-CE) has been implemented in a novel sequential injection-capillary electrophoresis instrument for the high-throughput determination of acidity constants (pK(a)) regardless of aqueous solubility, number of pK(a) values, or structure. This instrument comprises a buffer creation system that automatically mixes within a few seconds four reagents for in situ creation of the separation electrolyte with a pH range of 2-13, ionic strength of 10-100 mM and organic solvent content from 0% to 40%. Combined with 1.2 kV/cm and a short effective length (15 cm to the UV detector) fast 20 s electrophoretic separations can be obtained. The low standard deviation of the replicates and the low variation compared to reference values show that this system can accurately determine acidity constants of drugs by IS-CE. A single pK(a) can be determined in 2 min and a set of 20 measurements in half an hour, allowing rapid, simple, and flexible determination of pK(a) values of pharmaceutical targets.

  12. Improved theophylline serum analysis by an appropriate internal standard for gas chromatography.

    PubMed

    Bailey, D G; Davis, H L; Johnson, G E

    1976-06-23

    A gas chromatographic method is presented for the measurement of theophylline in serum. To serum samples containing the drug the internal standard, 3-isobutyl-l-methylxanthine, was added and the serum was saturated with ammonium carbonate. A mixture of isopropanol-chloroform (5:95) was used for extraction. The organic phase was filtered and evaporated. The residue, dissolved in chloroform, was extracted with sodium hydroxide. The basic solution was acidified, washed with hexane and reextracted with isopropanol-chloroform. The organic phase was dried with anhydrous sodium sulphate before evaporation. The sample was derivatized with n-Butyl-8 reagent. 85% of theophylline was recovered by extraction. 3-Isobutyl-l-methylxanthine was recovered with the same efficiency as theophylline and gas chromatographed well. The standard curve was linear between 1.0 and 50.0 mug/ml theophylline. No interference was encountered from normal serum constituents or methylxanthines such as caffeine, theobromine, or 3-methylxanthine. Serum samples were stared in the refrigerator for two weeks without significant loss of drug. The precision and accuracy of the method were good.

  13. Standardization of grading embryo morphology.

    PubMed

    Racowsky, Catherine; Vernon, Michael; Mayer, Jacob; Ball, G David; Behr, Barry; Pomeroy, Kimball O; Wininger, David; Gibbons, William; Conaghan, Joseph; Stern, Judy E

    2010-08-01

    Standardization of morphologic assessment for an embryo grading system was developed and is being implemented by the Society for Assisted Reproductive Technology (SART). A recent European consensus conference of embryologists from Europe and America is working toward adopting an embryo classification system modeled similarly to that of SART that, if adopted, would produce a de facto international standard to aid cross-border collaboration. PMID:20580357

  14. Collaborative study for the establishment of the WHO 3(rd) International Standard for Endotoxin, the Ph. Eur. endotoxin biological reference preparation batch 5 and the USP Reference Standard for Endotoxin Lot H0K354.

    PubMed

    Findlay, L; Desai, T; Heath, A; Poole, S; Crivellone, M; Hauck, W; Ambrose, M; Morris, T; Daas, A; Rautmann, G; Buchheit, K H; Spieser, J M; Terao, E

    2015-01-01

    An international collaborative study was organised jointly by the World Health Organization (WHO)/National Institute for Biological Standards and Control (NIBSC), the United States Pharmacopeia (USP) and the European Directorate for the Quality of Medicines & HealthCare (EDQM/Council of Europe) for the establishment of harmonised replacement endotoxin standards for these 3 organisations. Thirty-five laboratories worldwide, including Official Medicines Control Laboratories (OMCLs) and manufacturers enrolled in the study. Three candidate preparations (10/178, 10/190 and 10/196) were produced with the same material and same formulation as the current reference standards with the objective of generating a new (3(rd)) International Standard (IS) with the same potency (10 000 IU/vial) as the current (2(nd)) IS, as well as new European Pharmacopoeia (Ph. Eur.). and USP standards. The suitability of the candidate preparations to act as the reference standard in assays for endotoxin performed according to compendial methods was evaluated. Their potency was calibrated against the WHO 2(nd) IS for Endotoxin (94/580). Gelation and photometric methods produced similar results for each of the candidate preparations. The overall potency estimates for the 3 batches were comparable. Given the intrinsic assay precision, the observed differences between the batches may be considered unimportant for the intended use of these materials. Overall, these results were in line with those generated for the establishment of the current preparations of reference standards. Accelerated degradation testing of vials stored at elevated temperatures supported the long-term stability of the 3 candidate preparations. It was agreed between the 3 organisations that batch 10/178 be shared between WHO and EDQM and that batches 10/190 and 10/196 be allocated to USP, with a common assigned value of 10 000 IU/vial. This value maintains the continuity of the global harmonisation of reference materials and

  15. 25 CFR 542.42 - What are the minimum internal control standards for internal audit for Tier C gaming operations?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... credit procedures, pit credit play procedures, rim credit procedures, soft drop/count procedures and the... for compliance with information technology standards; (x) Complimentary service or item, including...

  16. 25 CFR 542.42 - What are the minimum internal control standards for internal audit for Tier C gaming operations?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... credit procedures, pit credit play procedures, rim credit procedures, soft drop/count procedures and the... for compliance with information technology standards; (x) Complimentary service or item, including...

  17. 76 FR 12923 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... Reciprocating Internal Combustion Engines AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule... internal combustion engines. The final rule was published on August 20, 2010. This action proposes to amend... internal combustion generation, engine. transmission, or distribution. 622110 Medical and...

  18. An Audit of Emergency Department Accreditation Based on Joint Commission International Standards (JCI)

    PubMed Central

    Hashemi, Behrooz; Motamedi, Maryam; Etemad, Mania; Rahmati, Farhad; Forouzanfar, Mohammad Mehdi; Kaghazchi, Fatemeh

    2014-01-01

    Introduction: Despite thousands of years from creation of medical knowledge, it not much passes from founding the health care systems. Accreditation is an effective mechanism for performance evaluation, quality enhancement, and the safety of health care systems. This study was conducted to assess the results of emergency department (ED) accreditation in Shohadaye Tajrish Hospital, Tehran, Iran, 2013 in terms of domesticated standards of joint commission international (JCI) standards. Methods: This cohort study with a four-month follow up was conducted in the ED of Shohadaye Tajrish Hospital in 2013. The standard evaluation checklist of Iran hospitals (based on JCI standards) included 24 heading and 337 subheading was used for this purpose. The effective possible causes of weak spots were found and their solutions considered. After correction, assessment of accreditation were repeated again. Finally, the achieved results of two periods were analyzed using SPSS version 20. Results: Quality improvement, admission in department and patient assessment, competency and capability test for staffs, collection and analysis of data, training of patients, and facilities had the score of below 50%. The mean of total score for accreditation in ED in the first period was 60.4±30.15 percent and in the second period 68.9±22.9 (p=0.005). Strategic plans, head of department, head nurse, resident physician, responsible nurse for the shift, and personnel file achieved the score of 100%. Of total headings below 50% in the first period just in two cases, collection and analysis of data with growth of 40% as well as competency and capability test for staffs with growth of 17%, were reached to more than 50%. Conclusion: Based on findings of the present study, the ED of Shohadaye Tajrish hospital reached the score of below 50% in six heading of quality improvement, admission in department and patient assessment, competency and capability test for staffs, collection and analysis of data

  19. Creating an educationally minded schedule: one approach to minimize the impact of duty hour standards on intern continuity clinic experience.

    PubMed

    DeBlasio, Dominick; Kerrey, M Kathleen; Sucharew, Heidi; Klein, Melissa

    2014-11-01

    To determine if implementing an educationally minded schedule utilizing consecutive night shifts can moderate the impact of the 2011 duty hour standards on education and patient continuity of care in longitudinal primary care experience (continuity clinic). A 14-month pre-post study was performed in continuity clinic with one supervising physician group and two intern groups. Surveys to assess attitudes and education were distributed to the supervising physicians and interns before and after the changes in duty hour standards. Intern groups' schedules were reviewed for the number of regular and alternative day clinic (i.e. primary care experience on a different weekday) sessions and patient continuity of care. Fifteen supervising physicians and 51 interns participated (25 in 2011, 26 in 2012). Intern groups' comfort when discussing patient issues, educational needs and teamwork perception did not differ. Supervising physicians' understanding of learning needs and provision of feedback did not differ between groups. Supervising physicians indicated a greater ability to provide feedback and understand learning needs during regular continuity clinic sessions compared with alternative day clinics (all p < 0.05). No significant difference was detected between intern groups in the number of regularly scheduled continuity clinics, alternative day clinics or patient continuity of care. The 2011 duty hour standards required significant alterations to intern schedules, but educationally minded scheduling limited impact on education and patient continuity in care. PMID:24841768

  20. Creating an educationally minded schedule: one approach to minimize the impact of duty hour standards on intern continuity clinic experience.

    PubMed

    DeBlasio, Dominick; Kerrey, M Kathleen; Sucharew, Heidi; Klein, Melissa

    2014-11-01

    To determine if implementing an educationally minded schedule utilizing consecutive night shifts can moderate the impact of the 2011 duty hour standards on education and patient continuity of care in longitudinal primary care experience (continuity clinic). A 14-month pre-post study was performed in continuity clinic with one supervising physician group and two intern groups. Surveys to assess attitudes and education were distributed to the supervising physicians and interns before and after the changes in duty hour standards. Intern groups' schedules were reviewed for the number of regular and alternative day clinic (i.e. primary care experience on a different weekday) sessions and patient continuity of care. Fifteen supervising physicians and 51 interns participated (25 in 2011, 26 in 2012). Intern groups' comfort when discussing patient issues, educational needs and teamwork perception did not differ. Supervising physicians' understanding of learning needs and provision of feedback did not differ between groups. Supervising physicians indicated a greater ability to provide feedback and understand learning needs during regular continuity clinic sessions compared with alternative day clinics (all p < 0.05). No significant difference was detected between intern groups in the number of regularly scheduled continuity clinics, alternative day clinics or patient continuity of care. The 2011 duty hour standards required significant alterations to intern schedules, but educationally minded scheduling limited impact on education and patient continuity in care.

  1. The Quality Adaptation Model: Adaptation and Adoption of the Quality Standard ISO/IEC 19796-1 for Learning, Education, and Training

    ERIC Educational Resources Information Center

    Pawlowski, Jan M.

    2007-01-01

    In 2005, the new quality standard for learning, education, and training, ISO/IEC 19796-1, was published. Its purpose is to help educational organizations to develop quality systems and to improve the quality of their processes, products, and services. In this article, the standard is presented and compared to existing approaches, showing the…

  2. The Changing Landscape of Alternate Assessments Based on Modified Academic Achievement Standards: An Analysis of Early Adopters of AA-MASs

    ERIC Educational Resources Information Center

    Lazarus, Sheryl S.; Thurlow, Martha L.

    2009-01-01

    Several states had an assessment that they considered to be an alternate assessment based on modified academic achievement standards (AA-MAS) in place, or in development, when the April 2007 federal regulations on modified achievement standards were finalized. This article uses publicly available information collected by the National Center on…

  3. Standardization of a new batch of purified tuberculin (PPD) intended for international use

    PubMed Central

    Guld, Johannes; Bentzon, M. Weis; Bleiker, M. A.; Griep, W. A.; Magnusson, Mogens; Waaler, Hans

    1958-01-01

    A new batch of PPD tuberculin, RT 23, prepared at the request of UNICEF by the Statens Seruminstitut, Copenhagen, has been compared with previous batches of tuberculin from the Statens Seruminstitut and with the International Standard for the Purified Protein Derivative of Mammalian Tuberculin. The comparisons were made by intradermal tuberculin testing. The majority of tests were carried out in human subjects with various types and levels of tuberculin sensitivity—namely, tuberculous patients in the Netherlands; BCG-vaccinated as well as spontaneously tuberculin-sensitive army recruits in the Netherlands; BCG-vaccinated schoolchildren in Denmark; population groups in the tropics (Mauritius and Nigeria) including a high proportion of persons with low-grade sensitivity. In addition, comparisons were made in guinea-pigs sensitized in different ways. For these comparisons, RT 23 was diluted both with phosphate-buffered saline alone (as were the other preparations) and with phosphate-buffered saline containing 0.05‰ Tween 80 as a stabilizing agent. The results were found to differe significantly with the type and level of sensitivity of the groups tested. Thus, while the potency ratio of RT 23 and the International Standard is about 2:1 in BCG-vaccinated persons, it is about 1:1 in persons with naturally acquired tuberculin sensitivity. RT 23 in diluent containing Tween 80 elicited larger reactions than did RT 23 in ordinary diluent; however, when reactions of the same size were compared, a difference in character was observed: the reactions to RT 23 diluted with Tween 80 were softer and less frequently bullous. On the basis of the results—in terms of reaction size—obtained in patients and in non-vaccinated recruits, it is suggested that one unit of RT 23 should be defined as 0.02 μg of the dry substance; for use as a first or single dose in routine testing, 0.02 μg of RT 23 in diluent stabilized with Tween 80, or 0.06 μg in diluent without Tween 80, is

  4. Standardization of microcystin extraction from fish tissues: a novel internal standard as a surrogate for polar and non-polar variants.

    PubMed

    Smith, Juliette L; Boyer, Gregory L

    2009-02-01

    Microcystins (MCs), a class of potent liver/hepatopancreatic toxins produced by numerous species of freshwater cyanobacteria, are well known for their toxic effects on aquatic organisms and humans. The extraction efficiencies of MCs can vary greatly as a result of matrix differences and/or differences in the extraction solvents, techniques, and clean-up steps utilized. Here we report the preparation of a unique internal standard, (S-hydroxypropyl-cys7)microcystin-LR (thiol-LR), with a mass different than any known MCs, which can be spiked into field samples and quantified via HPLC-MS along with endogenous MCs. Thiol-LR is modified at the Mdha residue, and therefore, provides an accurate measure of only free MCs that are not covalently bound to endogenous thiols in the matrix. The internal standard proved to be a good surrogate for MC-RR, -LR, and -LA in fish liver tissue. In fish muscle tissue, thiol-LR was a good surrogate for polar variants, MC-RR and -LR, but was less representative of the non-polar variant, MC-LA. Coupling of the internal standard (8 microg/g ww tissue) with HPLC-MS detection will standardize the quantification of free microcystins across species, tissue types, and extraction methods, making the estimation of exposure risk more reliable.

  5. Advantages and difficulties of implementation of the international GNA standards in sustainable mining development. (Invited)

    NASA Astrophysics Data System (ADS)

    Masaitis, A.

    2013-12-01

    Conflicts in the development of mining projects are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices in both developing and developed countries. The GNA project being currently developed at the University of Nevada, Reno in cooperation with the Newmont Mining Corporation has a goal to create an open company/community dialog that is based on the international standards and that will help identify and address sociological and environmental concerns associated with mining, as well as find methods for communication and conflict resolution. GNA standards should be based on trust doctrine, open information access, and community involvement in the decision making process. It should include the following components: emergency response and community communications; environmental issues, including air and water quality standards; reclamation and recultivation; socio-economic issues: transportation, safety, training, and local hiring; and financial issues, particularly related to mitigation offsets and community needs. The GNA standards help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; focus on the local political and government systems; separate the acute and the chronic concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the

  6. 25 CFR 542.32 - What are the minimum internal control standards for internal audit for Tier B gaming operations?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... play procedures, rim credit procedures, soft drop/count procedures and the subsequent transfer of funds... technology standards; (x) Complimentary service or item, including but not limited to, procedures...

  7. 25 CFR 542.22 - What are the minimum internal control standards for internal audit for Tier A gaming operations?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... play procedures, rim credit procedures, soft drop/count procedures and the subsequent transfer of funds... technology standards; (x) Complimentary service or item, including but not limited to, procedures...

  8. 25 CFR 542.22 - What are the minimum internal control standards for internal audit for Tier A gaming operations?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... play procedures, rim credit procedures, soft drop/count procedures and the subsequent transfer of funds... technology standards; (x) Complimentary service or item, including but not limited to, procedures...

  9. 25 CFR 542.32 - What are the minimum internal control standards for internal audit for Tier B gaming operations?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... play procedures, rim credit procedures, soft drop/count procedures and the subsequent transfer of funds... technology standards; (x) Complimentary service or item, including but not limited to, procedures...

  10. Ensuring good governance to address emerging and re-emerging animal disease threats: supporting the veterinary services of developing countries to meet OIE international standards on quality.

    PubMed

    Vallat, B; Mallet, E

    2006-04-01

    As an effect of increased globalisation, animal diseases, in particular those transmissible to man, have an immediate global economic and social impact. This fact, dramatically illustrated by the current avian influenza epizootic in South-East Asia and Eastern Europe, clearly demonstrates the crucial importance of the national Veterinary Services (VS) for the prevention, early detection and response for the efficient control of animal diseases. Complying with this mission for the VS presupposes the existence of appropriate governance and legislation and of an official system to control their quality and reliability- an obvious weakness in many developing and in transition countries. The World Organisation for Animal Health (OIE) has therefore developed a project aiming at strengthening the VS in those countries facing the greatest animal health threats and to bring them into line with OIE international standards already adopted by the same countries. Based on the evaluation of the VS and subsequent actions at the global, regional and national levels, the project will have a significant beneficial impact on the targeted countries as well as the international community as a whole, not only in the fields of agriculture, food security and production, and food safety, but also for the local and global prevention of emerging and re-emerging diseases of veterinary and public health importance. The project will be implemented in strong collaboration with the Food and Agriculture Organization. The actions proposed must be considered eligible for the concept of International Public Good. PMID:16796063

  11. Ensuring good governance to address emerging and re-emerging animal disease threats: supporting the veterinary services of developing countries to meet OIE international standards on quality.

    PubMed

    Vallat, B; Mallet, E

    2006-04-01

    As an effect of increased globalisation, animal diseases, in particular those transmissible to man, have an immediate global economic and social impact. This fact, dramatically illustrated by the current avian influenza epizootic in South-East Asia and Eastern Europe, clearly demonstrates the crucial importance of the national Veterinary Services (VS) for the prevention, early detection and response for the efficient control of animal diseases. Complying with this mission for the VS presupposes the existence of appropriate governance and legislation and of an official system to control their quality and reliability- an obvious weakness in many developing and in transition countries. The World Organisation for Animal Health (OIE) has therefore developed a project aiming at strengthening the VS in those countries facing the greatest animal health threats and to bring them into line with OIE international standards already adopted by the same countries. Based on the evaluation of the VS and subsequent actions at the global, regional and national levels, the project will have a significant beneficial impact on the targeted countries as well as the international community as a whole, not only in the fields of agriculture, food security and production, and food safety, but also for the local and global prevention of emerging and re-emerging diseases of veterinary and public health importance. The project will be implemented in strong collaboration with the Food and Agriculture Organization. The actions proposed must be considered eligible for the concept of International Public Good.

  12. Establishment of the 1st World Health Organization international standards for human papillomavirus type 16 DNA and type 18 DNA.

    PubMed

    Wilkinson, Dianna E; Baylis, Sally A; Padley, David; Heath, Alan B; Ferguson, Morag; Pagliusi, Sonia R; Quint, Wim G; Wheeler, Cosette M

    2010-06-15

    A World Health Organization collaborative study was conducted to evaluate candidate international standards for human papillomavirus (HPV) Type 16 DNA (NIBSC code 06/202) and HPV Type 18 DNA (NIBSC code 06/206) for use in the amplification and detection steps of nucleic acid-based assays. The freeze-dried candidate international standards were prepared from bulk preparations of cloned plasmid containing full-length HPV-16 or HPV-18 genomic DNA. Nineteen laboratories from 13 countries participated in the study using a variety of commercial and in-house quantitative and qualitative assays. The data presented here indicate that, upon freeze-drying, there is no significant loss in potency for the candidate HPV-18 DNA and a slight loss in potency for the candidate HPV-16 DNA; although this is likely not scientifically relevant when assay precision is considered. In general, the individual laboratory mean estimates for each study sample were grouped +/- approximately 2 log(10) around the theoretical HPV DNA concentration of the reconstituted ampoule (1 x 10(7) HPV genome equivalents/mL). The agreement between laboratories is improved when potencies are made relative to the candidate international standards, demonstrating their utility in harmonizing amplification and detection steps of HPV-16 and -18 DNA assays. Degradation studies indicate that the candidate international standards are extremely stable and suitable for long-term use. Based on these findings, the candidate standards were established as the 1st WHO international standards for HPV-16 DNA and HPV-18 DNA, each with a potency of 5 x 10(6) international units (IU) per ampoule or 1 x 10(7) IU mL(-1) when reconstituted as directed.

  13. Internal standards in fluorescent X-ray spectroscopy1 1 Publication authorized by the Director, U.S. Geological Survey.

    USGS Publications Warehouse

    Adler, I.; Axelrod, J.M.

    1955-01-01

    The use of internal standards in the analysis of ores and minerals of widely-varying matrix by means of fluorescent X-ray spectroscopy is frequently the most practical approach. Internal standards correct for absorption and enhancement effects except when an absorption edge falls between the comparison lines or a very strong emission line falls between the absorption edges responsible for the comparison lines. Particle size variations may introduce substantial errors. One method of coping with the particle size problem is grinding the sample with an added abrasive. ?? 1955.

  14. Using the CEN/ISO standard for categorial structure to harmonise the development of WHO international terminologies.

    PubMed

    Rodrigues, Jean M; Kumar, Anand; Bousquet, Cédric; Trombert, Béatrice

    2009-01-01

    Semantic interoperability (SIOp) is a major issue for health care systems having to share information across professionals, teams, legacies, countries, languages and citizens. The World Health Organisation (WHO) develops and updates a family of health care terminologies (ICD, ICF, ICHI and ICPS) and has embarked on an open web-based cooperation to revise ICD 11 using ontology driven tools. The International Health Terminology Standard Development Organisation (IHTSDO) updates, translates and maps SNOMED CT to ICD 10. We present the application of the CEN/ISO standard on categorial structure to bind terminologies and ontologies to harmonise and to map between these international terminologies.

  15. International organization for standardization (ISO) 9000 and chemical agent standard analytical reference material (SASARM) quality system development and implementation. Phase 1. Final report, April 1993-June 1994

    SciTech Connect

    Turley, S.D.

    1994-09-01

    U.S. Army Dugway Proving Ground (DPG) is in the process of developing an International Organization for Standardization (ISO) 9000 quality assurance (QA) system and a Chemical Agent Standard Analytical Reference Material (CASARM) QA program. Phase I of this process consisted of analyzing the current DPG QA system, defining the structure of the new QA system, determine how the ISO 9000 and the CASARM systems will interact, develop the new QA system and implementation plan, and develop the CASARM program and begin implementation. The initial phases of the system design and synthesis met the objectives established for Phase I of this methodology project. Phase II will complete the functional analysis, system design, and prototype implementation. The prototype will be analyzed for weaknesses in operation, personnel and equipment requirements, software, and cost effectiveness. The system will be modified, if needed, and implemented across the Materiel Test Directorate. The final stage of this methodology will be to achieve ISO 9000 registration. International Organization for Standardization(ISO) 9000, Chemical Agent Standard Analytical Reference Material(CASARM), Standardized Quality Assurance(QA), QA/Quality Control(QC).

  16. Physiological Employment Standards III: physiological challenges and consequences encountered during international military deployments.

    PubMed

    Nindl, Bradley C; Castellani, John W; Warr, Bradley J; Sharp, Marilyn A; Henning, Paul C; Spiering, Barry A; Scofield, Dennis E

    2013-11-01

    Modern international military deployments in austere environments (i.e., Iraq and Afghanistan) place considerable physiological demands on soldiers. Significant physiological challenges exist: maintenance of physical fitness and body composition, rigors of external load carriage, environmental extremes (heat, cold, and altitude), medical illnesses, musculoskeletal injuries, traumatic brain injuries, post-traumatic stress disorder, and environmental exposure hazards (i.e., burn pits, vehicle exhaust, etc.). To date there is very little published research and no comprehensive reviews on the physiological effects of deployments. The purpose of this paper is to overview what is currently known from the literature related mainly to current military conflicts with regard to the challenges and consequences from deployments. Summary findings include: (1) aerobic capacity declines while muscle strength, power and muscular endurance appear to be maintained, (2) load carriage continues to tax the physical capacities of the Soldier, (3) musculoskeletal injuries comprise the highest proportion of all injury categories, (4) environmental insults occur from both terrestrial extremes and pollutant exposure, and (5) post-deployment concerns linger for traumatic brain injury and post-traumatic stress disorder. A full understanding of these responses will assist in identifying the most effective risk mitigation strategies to ensure deployment readiness and to assist in establishment of military employment standards. PMID:23430237

  17. Mental health legislation in Lebanon: Nonconformity to international standards and clinical dilemmas in psychiatric practice.

    PubMed

    Kerbage, Hala; El Chammay, Rabih; Richa, Sami

    2016-01-01

    Mental health legislation represents an important mean of protecting the rights of persons with mental disabilities by preventing human rights violations and discrimination and by legally reinforcing the objectives of a mental health policy. The last decade has seen significant changes in the laws relating to psychiatric practice all over the world, especially with the implementation of the Convention for the Rights of People with Disabilities (CRPD). In this paper, we review the existing legislation in Lebanon concerning the following areas in mental health: treatment and legal protection of persons with mental disabilities, criminal laws in relation to offenders with mental disorders, and laws regulating incapacity. We will discuss these texts in comparison with international recommendations and standards on the rights of persons with disabilities, showing the recurrent contradiction between them. Throughout our article, we will address the clinical dilemmas that Lebanese psychiatrists encounter in practice, in the absence of a clear legislation that can orient their decisions and protect their patients from abuse.

  18. Determination of miconazole in pharmaceutical creams using internal standard and second derivative spectrophotometry.

    PubMed

    Wróbel, K; Wróbel, K; de la Garza Rodríguez, I M; López-de-Alba, P L; López-Martínez, L

    1999-06-01

    A simple method is proposed for miconazole determination in pharmaceutical creams, based on extraction and second derivative spectrophotometry. In the presence of sodium lauryl sulfate (0.5%) and sulphuric acid (0.4 mol l(-1)), the miconazole and internal standard (IS) (methylene blue) were extracted to 100 microl of methylene chloride. The organic phase was evaporated in the nitrogen stream and the dry residue was dissolved in methanol (1.5 ml). The analytical signal was obtained as the ratio between second derivative absorbances measured at 236.9 nm (miconazole) and at 663.2 nm (IS). The use of IS in such multi-stage procedure enabled quite good analytical performance in calibration range 50.0 400 mg l(-1): linear correlation coefficient 0.9995, precision (measured as CV for ten replicates) at 50.0 mg l(-1) and at 400 mg l(-1) of miconazole was 1.5 and 0.5% respectively. Four commercial pharmaceutical creams were analyzed and the results obtained were in good agreement with the results obtained by reversed-phase high performance liquid chromatography (HPLC).

  19. Development of an evaluation methodology for triple bottom line reports using international standards on reporting.

    PubMed

    Skouloudis, Antonis; Evangelinos, Konstantinos; Kourmousis, Fotis

    2009-08-01

    The purpose of this article is twofold. First, evaluation scoring systems for triple bottom line (TBL) reports to date are examined and potential methodological weaknesses and problems are highlighted. In this context, a new assessment methodology is presented based explicitly on the most widely acknowledged standard on non-financial reporting worldwide, the Global Reporting Initiative (GRI) guidelines. The set of GRI topics and performance indicators was converted into scoring criteria while the generic scoring devise was set from 0 to 4 points. Secondly, the proposed benchmark tool was applied to the TBL reports published by Greek companies. Results reveal major gaps in reporting practices, stressing the need for the further development of internal systems and processes in order to collect essential non-financial performance data. A critical overview of the structure and rationale of the evaluation tool in conjunction with the Greek case study is discussed while recommendations for future research on the field of this relatively new form of reporting are suggested.

  20. Development of an Evaluation Methodology for Triple Bottom Line Reports Using International Standards on Reporting

    NASA Astrophysics Data System (ADS)

    Skouloudis, Antonis; Evangelinos, Konstantinos; Kourmousis, Fotis

    2009-08-01

    The purpose of this article is twofold. First, evaluation scoring systems for triple bottom line (TBL) reports to date are examined and potential methodological weaknesses and problems are highlighted. In this context, a new assessment methodology is presented based explicitly on the most widely acknowledged standard on non-financial reporting worldwide, the Global Reporting Initiative (GRI) guidelines. The set of GRI topics and performance indicators was converted into scoring criteria while the generic scoring devise was set from 0 to 4 points. Secondly, the proposed benchmark tool was applied to the TBL reports published by Greek companies. Results reveal major gaps in reporting practices, stressing the need for the further development of internal systems and processes in order to collect essential non-financial performance data. A critical overview of the structure and rationale of the evaluation tool in conjunction with the Greek case study is discussed while recommendations for future research on the field of this relatively new form of reporting are suggested.

  1. United States Government Regulations and International Standards Related to Food Analysis

    NASA Astrophysics Data System (ADS)

    Nielsen, S. Suzanne

    Knowledge of government regulations relevant to the chemical analysis of foods is extremely important to persons working in the food industry. Federal laws and regulations reinforce the efforts of the food industry to provide wholesome foods, to inform consumers about the nutritional composition of foods, and to eliminate economic frauds. In some cases, they dictate what ingredients a food must contain, what must be tested, and the procedures used to analyze foods for safety factors and quality attributes. This chapter describes the US federal regulations related to the composition of foods. The reader is referred to references (1-4) for comprehensive coverage of US food laws and regulations. Many of the regulations referred to in this chapter are published in the various titles of the Code of Federal Regulations (CFR) (5). This chapter also includes information about food standards and safety practices established by international organizations. Internet addresses are given at the end of this chapter for many of the government agencies, organizations, and documents discussed.

  2. Acetone and Ethyl Acetate in Commercial Nail Polish Removers: A Quantitative NMR Experiment Using an Internal Standard

    NASA Astrophysics Data System (ADS)

    Clarke, David W.

    1997-12-01

    The qualitative and quantitative analysis of commercial nail polish removers is performed on a 60 MHz NMR spectrometer. After taking NMR spectra of the polish removers, students can make peak assignments for the known components of acetone and ethyl acetate. Using these spectra, students are also able to identify the unknown alcohol present in the remover as ethanol. Quantitative analysis of either the acetone or ethyl acetate in the nail polish removers is accomplished by comparing the analyte peak intensities with that of an internal standard. The system in which deuterated acetone is used as a solvent and methylene chloride as an internal standard gave precise results for both commercial removers and for standards prepared from pure acetone or an ethyl acetate/ethanol mixture. As recovery from the standards was approximately 96 - 98% of what was anticipated, the analysis of the commercial products is also believed to be accurate.

  3. Electronic book format EPUB and Japanese typography : Mainstream people in Japan are unlikely to win international standardization battles

    NASA Astrophysics Data System (ADS)

    Murata, Makoto

    EPUB3 is an electronic book format based on Web technologies such as HTML and CSS. EPUB3 is internationalized; in particular, it supports Japanese typography. Features such as vertical writing were introduced by first creating CSS Writing Modes and CSS Text at W3C and then creating EPUB3 at IDPF on top of them. On the basis of this standardization experience, common pitfalls for Japanese in international standardization are pointed out and a promising approach is suggested.

  4. Effects of the International Temperature Scale of 1990 (ITS-90) on CIE documentary standards for radiometry, photometry, and colorimetry

    SciTech Connect

    Mielenz, K.D.; Hsia, J.J.

    1990-01-01

    The differences between ITS-90 and IPTS-68 (International Practical Temperature Scale of 1968) above 1235 K are described. It is shown that none of the following CIE (Commission Internationale de l'Eclairage or International Commission on Illumination) definitions or recommendations require revision because of the introduction of the ITS-90: International Lighting Vocabulary definitions; CIE Standard Illuminants A, D(65), other illuminants; and sources for realizing CIE Illuminants. The effect of the ITS-90 on previously calibrated sources for realizing CIE illuminants is negligibly small.

  5. Strengthening Adoption Practice, Listening to Adoptive Families

    ERIC Educational Resources Information Center

    Atkinson, Anne; Gonet, Patricia

    2007-01-01

    In-depth interviews with 500 adoptive families who received postadoption services through Virginia's Adoptive Family Preservation (AFP) program paint a richly detailed picture of the challenges adoptive families face and what they need to sustain adoption for many years after finalization. Findings document the need for support in a variety of…

  6. 75 FR 80761 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... Reciprocating Internal Combustion Engines AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... air pollutants for reciprocating internal combustion engines and requesting public comment on one... the limitations on operation of emergency stationary engines to allow emergency engines to operate...

  7. 49 CFR 171.22 - Authorization and conditions for the use of international standards and regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Aviation Organization's Technical Instructions for the Safe Transport of Dangerous Goods by Air (ICAO Technical Instructions), the International Maritime Dangerous Goods Code (IMDG Code), Transport Canada's Transportation of Dangerous Goods Regulations (Transport Canada TDG Regulations), and the International...

  8. 49 CFR 171.22 - Authorization and conditions for the use of international standards and regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Aviation Organization's Technical Instructions for the Safe Transport of Dangerous Goods by Air (ICAO Technical Instructions), the International Maritime Dangerous Goods Code (IMDG Code), Transport Canada's Transportation of Dangerous Goods Regulations (Transport Canada TDG Regulations), and the International...

  9. 49 CFR 171.22 - Authorization and conditions for the use of international standards and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Aviation Organization's Technical Instructions for the Safe Transport of Dangerous Goods by Air (ICAO Technical Instructions), the International Maritime Dangerous Goods Code (IMDG Code), Transport Canada's Transportation of Dangerous Goods Regulations (Transport Canada TDG Regulations), and the International...

  10. 49 CFR 171.22 - Authorization and conditions for the use of international standards and regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Aviation Organization's Technical Instructions for the Safe Transport of Dangerous Goods by Air (ICAO Technical Instructions), the International Maritime Dangerous Goods Code (IMDG Code), Transport Canada's Transportation of Dangerous Goods Regulations (Transport Canada TDG Regulations), and the International...

  11. 40 CFR 60.4201 - What emission standards must I meet for non-emergency engines if I am a stationary CI internal...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... non-emergency engines if I am a stationary CI internal combustion engine manufacturer? 60.4201 Section... Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4201 What emission standards must I meet for non-emergency engines if I am a stationary CI internal combustion engine...

  12. 40 CFR 60.4201 - What emission standards must I meet for non-emergency engines if I am a stationary CI internal...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... non-emergency engines if I am a stationary CI internal combustion engine manufacturer? 60.4201 Section... Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4201 What emission standards must I meet for non-emergency engines if I am a stationary CI internal combustion engine...

  13. 40 CFR 60.4201 - What emission standards must I meet for non-emergency engines if I am a stationary CI internal...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... non-emergency engines if I am a stationary CI internal combustion engine manufacturer? 60.4201 Section... Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4201 What emission standards must I meet for non-emergency engines if I am a stationary CI internal combustion engine...

  14. 40 CFR 60.4201 - What emission standards must I meet for non-emergency engines if I am a stationary CI internal...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... non-emergency engines if I am a stationary CI internal combustion engine manufacturer? 60.4201 Section... Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4201 What emission standards must I meet for non-emergency engines if I am a stationary CI internal combustion engine...

  15. 40 CFR 60.4201 - What emission standards must I meet for non-emergency engines if I am a stationary CI internal...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... non-emergency engines if I am a stationary CI internal combustion engine manufacturer? 60.4201 Section... Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4201 What emission standards must I meet for non-emergency engines if I am a stationary CI internal combustion engine...

  16. 76 FR 68829 - International Standards on the Transport of Dangerous Goods; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... posted when available at http://www.phmsa.dot.gov/hazmat/regs/international . FOR FURTHER INFORMATION....gov/hazmat/regs/international . Following the 40th session of the UNSCOE TDG, PHMSA will place a copy... site at http://www.phmsa.dot.gov/hazmat/regs/international . PHMSA's site at...

  17. 77 FR 33019 - International Standards on the Transport of Dangerous Goods; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... http://www.phmsa.dot.gov/hazmat/regs/international . Failure to pre-register may delay your access to... will be posted when available at http://www.phmsa.dot.gov/hazmat/regs/international . FOR FURTHER....gov/hazmat/regs/international provides additional information regarding the UNSCOE TDG and...

  18. CTEPP STANDARD OPERATING PROCEDURE FOR CONDUCTING INTERNAL FIELD AUDITS AND QUALITY CONTROL (SOP-2.25)

    EPA Science Inventory

    This SOP describes the method for conducting internal field audits and quality control procedures. Internal field audits will be conducted to ensure the collection of high quality data. Internal field audits will be conducted by Field Auditors (the Field QA Officer and the Field...

  19. 75 FR 75937 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... ignition (CI) reciprocating internal combustion engines (RICE) (75 FR 9648). The final NESHAP for... Stationary Spark Ignition Internal Combustion Engines. 75 FR 32612 (June 8, 2010). In that action, EPA... Reciprocating Internal Combustion Engines AGENCY: Environmental Protection Agency (EPA). ACTION: Notice...

  20. Adoption Activities on the Internet: A Call for Regulation

    ERIC Educational Resources Information Center

    Roby, Jini L.; White, Holly

    2010-01-01

    There is a growing practice of adoption services on the Internet with varying degrees of regulation, depending on whether it is domestic infant adoption, public foster care adoption, or international adoption. Regulation is particularly lacking in domestic infant adoptions, with Web sites connecting prospective birth and adoptive parents,…

  1. 25 CFR 543.18 - What are the minimum internal control standards for the cage, vault, kiosk, cash and cash...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... cage, vault, kiosk, cash and cash equivalents? 543.18 Section 543.18 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING... address, and signature; (iii) For personal checks, verify the patron's check cashing authority and...

  2. 25 CFR 543.18 - What are the minimum internal control standards for the cage, vault, kiosk, cash and cash...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... cage, vault, kiosk, cash and cash equivalents? 543.18 Section 543.18 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING... address, and signature; (iii) For personal checks, verify the patron's check cashing authority and...

  3. Standard Setting for Next Generation TOEFL Academic Speaking Test (TAST): Reflections on the ETS Panel of International Teaching Assistant Developers

    ERIC Educational Resources Information Center

    Papajohn, Dean

    2006-01-01

    While many institutions have utilized TOEFL scores for international admissions for many years, a speaking section has never before been a required part of TOEFL until the development of the iBT/Next Generation TOEFL. So institutions will need to determine how to set standards for the speaking section of TOEFL, also known as TOEFL Academic…

  4. 25 CFR 543.20 - What are the minimum internal control standards for information technology and information...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... performed in accordance with 25 CFR 547.12. (l) Verifying downloads. Following download of any Class II... information technology and information technology data? 543.20 Section 543.20 Indians NATIONAL INDIAN GAMING... § 543.20 What are the minimum internal control standards for information technology and...

  5. 25 CFR 543.20 - What are the minimum internal control standards for information technology and information...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... performed in accordance with 25 CFR 547.12. (l) Verifying downloads. Following download of any Class II... information technology and information technology data? 543.20 Section 543.20 Indians NATIONAL INDIAN GAMING... § 543.20 What are the minimum internal control standards for information technology and...

  6. Selected Lessons Learned through the ISS Design, Development, Assembly, and Operations: Applicability to International Cooperation for Standardization

    NASA Technical Reports Server (NTRS)

    Hirsch, David B.

    2009-01-01

    This slide presentation reviews selected lessons that were learned during the design, development, assembly and operation of the International Space Station. The critical importance of standards and common interfaces is emphasized to create a common operation environment that can lead to flexibility and adaptability.

  7. Deconstructing Institutionalisation of the European Standards for Quality Assurance: From Instrument Mixes to Quality Cultures and Implications for International Research

    ERIC Educational Resources Information Center

    Kohoutek, Jan

    2016-01-01

    The paper enquires into the implementation of the European Standards and Guidelines for Internal Quality Assurance of Higher Education Institutions (ESG 1). The enquiry uses data from universities in the Czech Republic and compares them against those obtained in the relevant pan-European survey. The aims are to empirically deconstruct ESG 1…

  8. Adherence to ethical standards in publishing scientific articles: a statement from the International Journal of Cardiology.

    PubMed

    Shewan, Louise G; Coats, Andrew J S

    2012-11-29

    All authors of manuscripts in the International Journal of Cardiology are required to make a binding statement that they as authors adhere to the following principles: 1. That the corresponding author has the approval of all other listed authors for the submission and publication of all versions of the manuscript. 2. That all people who have the right to be recognised as authors have been included on the list of authors and everyone listed as an author has made an independent material contribution to the manuscript. 3. That the work submitted in the manuscript is original and has not been published elsewhere and is not presently under consideration of publication by any other journal other than in oral, poster or abstract format. 4. That the material in the manuscript has been acquired according to modern ethical standards and has been approved by the legally appropriate ethical committee. 5. That the article does not contain material copied from anyone else without their written permission and that all material which derives from prior work, including from the same authors, is properly attributed to the prior publication by proper citation. 6. That all material conflicts of interest have been declared including the use of paid medical writers and their funding source. 7. That the manuscript will be maintained on the servers of the journal and held to be a valid publication by the journal only as long as all statements in these principles remain true. 8. That if any of the statements above ceases to be true the authors have a duty to notify the journal as soon as possible so that the manuscript can be withdrawn. PMID:23106906

  9. Results of international standard problem No. 36 severe fuel damage experiment of a VVER fuel bundle

    SciTech Connect

    Firnhaber, M.; Yegorova, L.; Brockmeier, U.

    1995-09-01

    International Standard Problems (ISP) organized by the OECD are defined as comparative exercises in which predictions with different computer codes for a given physical problem are compared with each other and with a carefully controlled experimental study. The main goal of ISP is to increase confidence in the validity and accuracy of analytical tools used in assessing the safety of nuclear installations. In addition, it enables the code user to gain experience and to improve his competence. This paper presents the results and assessment of ISP No. 36, which deals with the early core degradation phase during an unmitigated severe LWR accident in a Russian type VVER. Representatives of 17 organizations participated in the ISP using the codes ATHLET-CD, ICARE2, KESS-III, MELCOR, SCDAP/RELAP5 and RAPTA. Some participants performed several calculations with different codes. As experimental basis the severe fuel damage experiment CORA-W2 was selected. The main phenomena investigated are thermal behavior of fuel rods, onset of temperature escalation, material behavior and hydrogen generation. In general, the calculations give the right tendency of the experimental results for the thermal behavior, the hydrogen generation and, partly, for the material behavior. However, some calculations deviate in important quantities - e.g. some material behavior data - showing remarkable discrepancies between each other and from the experiments. The temperature history of the bundle up to the beginning of significant oxidation was calculated quite well. Deviations seem to be related to the overall heat balance. Since the material behavior of the bundle is to a great extent influenced by the cladding failure criteria a more realistic cladding failure model should be developed at least for the detailed, mechanistic codes. Regarding the material behavior and flow blockage some models for the material interaction as well as for relocation and refreezing requires further improvement.

  10. Medical Issues in Adoption

    MedlinePlus

    ... to Know About Zika & Pregnancy Medical Issues in Adoption KidsHealth > For Parents > Medical Issues in Adoption Print ... or emotional abuse of the child continue Agency Adoptions If you adopt through an agency, you might ...

  11. The Translation of Leadership Standards into Leadership Practices: A Qualitative Analysis of the Adoption of the Ontario Leadership Framework in Urban Schools

    ERIC Educational Resources Information Center

    Riveros, Augusto; Verret, Carolyne; Wei, Wei

    2016-01-01

    Purpose: The guiding question of this study is: how is the Ontario Leadership Framework (OLF) translated into practices in elementary and secondary schools in the province of Ontario? The purpose of this paper is to provide a contextual account of the processes by which school leadership standards are incorporated into the practices of school…

  12. The Origins of the Standards Movement in the United States: Adoption of the Written Test and Its Influence on Class Work

    ERIC Educational Resources Information Center

    Miyamoto, Kenichiro

    2008-01-01

    Every state in the United States, under the NCLB act, has set state standards and is testing all students in grades 3-8. Students are given printed questions to which they write answers with a pencil on an answer sheet. These written tests are usually given to determine the academic achievements of students. This paper traces the early history of…

  13. Selenium determination in biscuits and pasta: development of chronopotentiometric stripping determination by using a sulphide as an internal standard.

    PubMed

    Svarc-Gajić, Jaroslava; Stojanović, Zorica

    2013-10-15

    Being common in chromatographic techniques internal standard method is rarely applied in electrochemical stripping determinations. One of the reasons for such rare use of this elegant quantification method is because optimal conditions of accumulation at the electrode for individual compounds producing a reproducible signal may vary significantly. These criteria are much stricter when selenium is in question due to very complex mechanism of its accumulation at mercury electrodes which implies simultaneous cathodic mercury dissolution and chemical reaction. Elements that are in the analytical step stripped cathodically from mercury electrodes are rare, further limiting the application of the internal standard method when electrochemical selenium determination is in question. In this work the possibility of using sulphide for selenium quantification by chronopotentiometric stripping analysis was investigated. Optimal experimental parameters were defined in two-component systems. Dimensionless factors defining the ratio of proportionality constants of the two elements were calculated for different selenium concentration ranges at different sulphide contents. Sulphide content that was chosen as adequate for selenium concentrations reasonably to be expected in food samples was 500 µg/dm(3). Determined detection limit of chronopotentiometric stripping determination of selenium by using a sulphide as an internal standard was 0.04 µg/dm(3) (RSD=7.6%; n=5). Defined quantification method was confirmed by analysing spiked standard solutions and standard reference material. The method was used for selenium determination in biscuit and pasta samples. Calculated contents were statistically compared with those obtained by using graphite furnace atomic absorption spectrometry.

  14. Report from AmSECT’s International Consortium for Evidence-Based Perfusion: American Society of ExtraCorporeal Technology Standards and Guidelines for Perfusion Practice: 2013

    PubMed Central

    Baker, Robert A.; Bronson, Shahna L.; Dickinson, Timothy A.; Fitzgerald, David C.; Likosky, Donald S.; Mellas, Nicholas B.; Shann, Kenneth G.

    2013-01-01

    Abstract: One of the roles of a professional society is to develop standards and guidelines of practice as an instrument to guide safe and effective patient care. The American Society of Extracorporeal Technology (AmSECT) first published its Essentials for Perfusion Practice, Clinical Function: Conduct of Extracorporeal Circulation in 1993. The International Consortium for Evidence-Based Perfusion (ICEBP), a committee within AmSECT, was tasked with updating this document in 2010. The aim of this report is to describe the method of development and content of AmSECT’s new professional standards and guidelines. The ICEBP committee independently evaluated and provided input regarding the current “Essentials and Guidelines.” Structural changes were made to the entire document, and a draft document was developed, presented, and circulated to the AmSECT Board of Directors and broader membership for comment. Informed by these reviews, a revised document was then presented to the Society for a membership vote. The final document consists of 15 areas of practice covered by 50 Standards and 38 Guidelines (see Appendix 1) with the first standard focusing on the development of institutional protocols to support their implementation and use. A majority of the membership voted to accept the document (81.2% of the voting membership accepting, 18.8% rejecting). After an audit of the balloting process by AmSECT’s Ethics Committee, the results were reported to the membership and the document was officially adopted on July 24, 2013. The Standards and Guidelines will serve as a useful guide for cardiac surgical teams that wish to develop institution-specific standards and guidelines to improve the reliability, safety, and effectiveness of adult cardiopulmonary bypass. The ICEBP recognizes that the development of a Standards and Guidelines statement alone will not change care. Safe, reliable, and effective care will be best served through the development and implementation of

  15. 25 CFR 542.10 - What are the minimum internal control standards for keno?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... following standards shall apply if a rabbit ear or wheel system is utilized: (i) A dedicated camera shall be... Tribal gaming regulatory authority upon request. (i) System security standards. (1) All keys...

  16. Establishment of the first international standard for PEGylated granulocyte colony stimulating factor (PEG-G-CSF): Report of an international collaborative study

    PubMed Central

    Wadhwa, Meenu; Bird, Chris; Dougall, Thomas; Rigsby, Peter; Bristow, Adrian; Thorpe, Robin

    2015-01-01

    We assessed the feasibility of developing a suitable international reference standard for determination of in vitro biological activity of human sequence recombinant PEG-G-CSF products with a 20 kD linear PEG linked to the N-terminal methionyl residue of G-CSF (INN Filgrastim), produced using a conjugation process and coupling chemistry similar to that employed for the lead PEGfilgrastim product. Based on initial data which showed that the current WHO 2nd international standard, IS for G-CSF (09/136) or alternatively, a PEG-G-CSF standard with a unitage traceable to the G-CSF IS may potentially serve as the IS for PEG-G-CSF products, two candidate preparations of PEG-G-CSF were formulated and lyophilized at NIBSC. These preparations were tested by 23 laboratories using in vitro bioassays in a multi-centre collaborative study. Results indicated that on the basis of parallelism, the current WHO 2nd IS for G-CSF or any of the PEG-G-CSF samples could be used as the international standard for PEG-G-CSF preparations. However, because of the variability in potency estimates seen when PEG-G-CSF preparations were compared with the current WHO 2nd IS for G-CSF, a candidate PEG-G-CSF was suitable as the WHO IS. The preparation 12/188 was judged suitable to serve as the WHO IS based on in vitro biological activity data. Therefore, the preparation coded 12/188 was established by the WHO Expert Committee on Biological Standardization (ECBS) in 2013 as the WHO 1st IS for human PEGylated G-CSF with an assigned in vitro bioactivity of 10,000 IU per ampoule. PMID:25450254

  17. Field Test Protocol. Standard Internal Load Generation for Unoccupied Test Homes

    SciTech Connect

    Fang, X.; Christensen, D.; Barker, G.; Hancock, E.

    2011-06-01

    This document describes a simple and general way to generate House Simulation Protocol (HSP)-consistent internal sensible and latent loads in unoccupied homes. It is newly updated based on recent experience, and provides instructions on how to calculate and set up the operational profiles in unoccupied homes. The document is split into two sections: how to calculate the internal load magnitude and schedule, and then what tools and methods should be used to generate those internal loads to achieve research goals.

  18. Field Test Protocol: Standard Internal Load Generation in Unoccupied Test Homes

    SciTech Connect

    Fang, X.; Christensen, D.; Barker, G.; Hancock, E.

    2011-06-01

    This document describes a simple and general way to generate House Simulation Protocol (HSP)-consistent internal sensible and latent loads in unoccupied homes. It is newly updated based on recent experience, and provides instructions on how to calculate and set up the operational profiles in unoccupied homes. The document is split into two sections: how to calculate the internal load magnitude and schedule, and then what tools and methods should be used to generate those internal loads to achieve research goals.

  19. The Use of the International Standard Bibliographic Description (ISBD) in Nigeria.

    ERIC Educational Resources Information Center

    Bankole, Beatrice S.

    Implementation of ISBD in Nigeria has successfully overcome problems with the diversities of 200 ethnic groups, 400 languages and dialects (in addition to English as the official language), arabic and roman alphabets, and the interface of two major religious systems--Islam and Christianity. This paper describes the adoption and uses of the ISBDs…

  20. 77 FR 69927 - International Standards on the Transport of Dangerous Goods; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... this meeting by completing the form at http://www.phmsa.dot.gov/hazmat/regs/international . Failure to... available at http://www.phmsa.dot.gov/hazmat/regs/international . FOR FURTHER INFORMATION CONTACT: Vincent.../main/dgdb/dgsubc3/c3rep.html . PHMSA's site at...