Science.gov

Sample records for adults exhibited significantly

  1. 77 FR 31420 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Alighiero Boetti: Game Plan... determine that the objects to be included in the exhibition ``Alighiero Boetti: Game Plan'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects...

  2. 78 FR 7849 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Edwardian Opulence: British Art at... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Edwardian... within the United States, are of cultural significance. The objects are imported pursuant to...

  3. 77 FR 31909 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``50th Anniversary Remembrance of the..., 2003), I hereby determine that the object to be included in the exhibition ``50th Anniversary... within the United States, is of cultural significance. The object is imported pursuant to a...

  4. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Dena'inaq' Huch'ulyeshi: The Dena..., 2003, I hereby determine that the objects to be included in the exhibition ``Dena'inaq' Huch'ulyeshi..., are of cultural significance. The objects are imported pursuant to loan agreements with the...

  5. 75 FR 6079 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Compass and Rule: Architecture as... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Compass and Rule... within the United States, are of cultural significance. The objects are imported pursuant to...

  6. 78 FR 25337 - Culturally Significant Object Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Bronze Statue of a Boxer, Hellenistic..., 2003), I hereby determine that the object to be included in the exhibition ``Bronze Statue of a Boxer... significance. The object is imported pursuant to a loan agreement with the foreign owner or custodian. I...

  7. 76 FR 68808 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Transition to Christianity: Art of... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Transition to... the United States, are of cultural significance. The objects are imported pursuant to loan...

  8. 77 FR 18295 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Roy Lichtenstein: A Retrospective... determine that the objects to be included in the exhibition ``Roy Lichtenstein: A Retrospective'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  9. 76 FR 61472 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Game of Kings: Medieval Ivory... Kings: Medieval Ivory Chessmen from the Isle of Lewis,'' imported from abroad for temporary...

  10. Conversational Competency Profiles of Adult Males Who Exhibit Fluency Disorders.

    ERIC Educational Resources Information Center

    Thorpe, Carol D.

    The study explored the verbal and nonverbal conversational competency of five adult males who exhibited fluency disorders. Five subject/interactant videotaped conversational interactions were analyzed utilizing an INter-REActive Learning (INREAL) Model analysis format. Descriptive individual and composite profiles resulting from trained raters'…

  11. 76 FR 23642 - Culturally Significant Object Imported for Exhibition Determinations: “Sarcophagus”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Sarcophagus'' SUMMARY: Notice is..., I hereby determine that the object to be included in the exhibition ``Sarcophagus,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object...

  12. 78 FR 53816 - Culturally Significant Objects Imported for Exhibition Determinations: “Van Gogh Repetitions”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Van Gogh Repetitions'' SUMMARY... that the objects to be included in the exhibition ``Van Gogh Repetitions,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are...

  13. 78 FR 60994 - Culturally Significant Objects Imported for Exhibition Determinations: “Christopher Wool”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Christopher Wool'' SUMMARY: Notice... objects to be included in the exhibition ``Christopher Wool,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  14. 77 FR 26814 - Culturally Significant Objects Imported for Exhibition Determinations: “Modern Landscapes”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Modern Landscapes'' SUMMARY: Notice... objects to be included in the exhibition ``Modern Landscapes,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  15. 78 FR 4586 - Culturally Significant Object Imported for Exhibition Determinations: “Gutai: Splendid Playground”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Gutai: Splendid Playground'' SUMMARY... object to be included in the exhibition ``Gutai: Splendid Playground,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported...

  16. 77 FR 38374 - Culturally Significant Objects Imported for Exhibition Determinations: “Drawing Surrealism”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Drawing Surrealism'' SUMMARY: Notice... objects to be included in the exhibition ``Drawing Surrealism'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  17. 78 FR 59750 - Culturally Significant Objects Imported for Exhibition Determinations: “Isa Genzken: Retrospective”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Isa Genzken: Retrospective'' SUMMARY... objects to be included in the exhibition ``Isa Genzken: Retrospective,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are...

  18. 78 FR 52601 - Culturally Significant Objects Imported for Exhibition Determinations: “Koloman Moser”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Koloman Moser'' ACTION: Notice....'' The referenced notice is corrected here to include additional objects as part of the exhibition... additional objects to be included in the exhibition ``Koloman Moser,'' imported from abroad for...

  19. 75 FR 1680 - Culturally Significant Objects Imported for Exhibition Determinations: “Roman Art”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Roman Art'' SUMMARY: Notice is... included in the exhibition ``Roman Art,'' imported from abroad for temporary exhibition within the...

  20. 75 FR 53731 - Culturally Significant Objects Imported for Exhibition Determinations: “Contemporary Argentine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Contemporary Argentine Masterworks... of August 28, 2000, I hereby determine that the objects to be included in the exhibition..., are of cultural significance. The objects are imported pursuant to loan agreements with the...

  1. Significance of Adult Pedestrian Torso Injury

    PubMed Central

    Ivarsson, B. Johan; Henary, Basem; Crandall, Jeff R.; Longhitano, Douglas

    2005-01-01

    The current paper uses data from two trauma registries to evaluate the significance of adult pedestrian torso injury relative to head and lower extremity injuries and to determine the relative importance of injuries to individual torso organs/structures. Analyses are conducted with and without adjusting for striking vehicle body type (car versus LTV). Although the incidence of torso injury is approximately 50% higher in pedestrians struck by LTVs than in those struck by cars, torso injury appears to be as an important contributor to the overall cost of pedestrian morbidity as is lower extremity injury. The most frequently injured torso organs/structures include the rib cage, lung & pleura, and liver. The results indicate a need for an increased focus on the prevention of torso injury in the design of pedestrian safety countermeasures. PMID:16179153

  2. 77 FR 54647 - Culturally Significant Objects Imported for Exhibition Determinations: “Manet: Portraying Life”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Manet: Portraying Life'' SUMMARY... objects to be included in the exhibition ``Manet: Portraying Life,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  3. 78 FR 25780 - Culturally Significant Objects Imported for Exhibition Determinations: “Koloman Moser”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Koloman Moser'' SUMMARY: Notice is... objects to be included in the exhibition ``Koloman Moser,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  4. 78 FR 33885 - Culturally Significant Object Imported for Exhibition Determinations: “Fauno Rosso”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Fauno Rosso'' SUMMARY: Notice is... object to be included in the exhibition ``Fauno Rosso,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  5. 77 FR 18295 - Culturally Significant Objects Imported for Exhibition Determinations: “Decree Stele”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Decree Stele'' SUMMARY: Notice is... object to be included in the exhibition ``Decree Stele'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  6. 78 FR 22362 - Culturally Significant Objects Imported for Exhibition Determinations: “40 Part Motet”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``40 Part Motet'' SUMMARY: Notice is... objects to be included in the exhibition ``40 Part Motet,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to a...

  7. 76 FR 81004 - Culturally Significant Object Imported for Exhibition Determinations: “Nordkapp”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Nordkapp'' SUMMARY: Notice is hereby... object to be included in the exhibition ``Nordkapp,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  8. 78 FR 54364 - Culturally Significant Objects Imported for Exhibition Determinations: “Jewels by JAR”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Jewels by JAR'' SUMMARY: Notice is... objects to be included in the exhibition ``Jewels by JAR,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  9. 76 FR 78716 - Culturally Significant Objects Imported for Exhibition Determinations: “Hilda With Bluebells”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hilda With Bluebells'' SUMMARY... object to be included in the exhibition ``Hilda with Bluebells,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  10. 76 FR 67017 - Culturally Significant Object Imported for Exhibition Determinations: “La Surprise”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... Culturally Significant Object Imported for Exhibition Determinations: ``La Surprise'' SUMMARY: Notice is... object to be included in the exhibition ``La Surprise,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  11. 76 FR 37392 - Culturally Significant Object Imported for Exhibition; Determinations: “Ostalgia”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... Culturally Significant Object Imported for Exhibition; Determinations: ``Ostalgia'' SUMMARY: Notice is hereby... hereby determine that the object to be included in the exhibition ``Ostalgia'', imported from abroad for temporary exhibition within the United States, is of cultural significance. The object, ``Three Capacity...

  12. 78 FR 46402 - Culturally Significant Object Imported for Exhibition Determinations: “The Dying Gaul”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... Culturally Significant Object Imported for Exhibition Determinations: ``The Dying Gaul'' SUMMARY: Notice is... object to be included in the exhibition ``The Dying Gaul,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  13. 78 FR 28939 - Culturally Significant Objects Imported for Exhibition Determinations: “Tomoaki Suzuki”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Tomoaki Suzuki'' SUMMARY: Notice is... objects to be included in the exhibition ``Tomoaki Suzuki,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to a...

  14. 77 FR 54646 - Culturally Significant Objects Imported for Exhibition Determinations: “Becoming Van Gogh”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Becoming Van Gogh'' SUMMARY: Notice... objects to be included in the exhibition ``Becoming Van Gogh,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  15. 77 FR 53959 - Culturally Significant Object Imported for Exhibition Determinations: “Pedimental Relief”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Pedimental Relief'' SUMMARY: Notice... object to be included in the exhibition ``Pedimental Relief,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  16. 78 FR 48539 - Culturally Significant Objects Imported for Exhibition Determinations: “Iran Modern”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Iran Modern'' SUMMARY: Notice is... objects to be included in the exhibition ``Iran Modern,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  17. 76 FR 58075 - Culturally Significant Object Imported for Exhibition Determinations: “Cervera Bible”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Cervera Bible'' SUMMARY: Notice is... object to be included in the exhibition ``Cervera Bible,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  18. 77 FR 20476 - Culturally Significant Objects Imported for Exhibition Determinations: “Nicolai Fechin”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Nicolai Fechin'' SUMMARY: Notice is... objects to be included in the exhibition ``Nicolai Fechin,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  19. 76 FR 77582 - Culturally Significant Objects Imported for Exhibition Determinations: “Cindy Sherman”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Cindy Sherman'' SUMMARY: Notice is... objects to be included in the exhibition ``Cindy Sherman,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  20. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Double Sexus”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Double Sexus'' SUMMARY: Notice is..., I hereby determine that the objects to be included in the exhibition ``Double Sexus,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects...

  1. 77 FR 56697 - Culturally Significant Object Imported for Exhibition Determinations: “Steve McQueen”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Steve McQueen'' SUMMARY: Notice is... object to be included in the exhibition ``Steve McQueen,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object is imported pursuant to a...

  2. 78 FR 51803 - Culturally Significant Objects Imported for Exhibition Determinations: “Nice: Luc Tuymans”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Nice: Luc Tuymans'' SUMMARY: Notice... objects to be included in the exhibition ``Nice: Luc Tuymans,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  3. 76 FR 64423 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 96: Haris...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Projects 96: Haris Epaminonda... determine that the objects to be included in the exhibition ``Projects 96: Haris Epaminonda'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects...

  4. 75 FR 20873 - Culturally Significant Objects Imported for Exhibition Determinations: “The Glory of Ukraine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Glory of Ukraine: Golden... Ukraine: Golden Treasures and Lost Civilizations,'' imported from abroad for temporary exhibition...

  5. 77 FR 53248 - Culturally Significant Objects Imported for Exhibition Determinations: “Swiss Treasures: From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Swiss Treasures: From Biblical... exhibition ``Swiss Treasures: From Biblical Papyrus and Parchment to Erasmus, Zwingli, Calvin, and...

  6. 75 FR 80885 - Culturally Significant Objects Imported for Exhibition Determinations: “The Buddhist Heritage of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Buddhist Heritage of Pakistan... Buddhist Heritage of Pakistan,'' imported from abroad for temporary exhibition within the United...

  7. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Wols: Retrospective”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Wols: Retrospective'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Wols: Retrospective... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  8. 78 FR 79057 - Culturally Significant Objects Imported for Exhibition Determinations: “Gauguin: Metamorphoses”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Gauguin: Metamorphoses'' SUMMARY..., I hereby determine that the objects to be included in the exhibition, ``Gauguin: Metamorphoses... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  9. 75 FR 74768 - Culturally Significant Objects Imported for Exhibition Determinations: “Norwegian Painters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Norwegian Painters'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Norwegian Painters... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  10. 78 FR 5555 - Culturally Significant Objects Imported for Exhibition Determinations: “SHANGAA, Art of Tanzania”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``SHANGAA, Art of Tanzania'' SUMMARY... objects to be included in the exhibition ``SHANGAA, Art of Tanzania,'' imported from abroad for...

  11. 77 FR 61045 - Culturally Significant Objects Imported for Exhibition Determinations: “China's Terracotta...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``China's Terracotta Warriors: The... Terracotta Warriors: The First Emperor's Legacy,'' imported from abroad for temporary exhibition within...

  12. 76 FR 53993 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2011: Zhang Dali... objects to be included in the exhibition ``New Photography 2011: Zhang Dali, Moyra Davey, George...

  13. 75 FR 28848 - Culturally Significant Objects Imported for Exhibition Determinations: “The Original Copy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Original Copy: Photography of... hereby determine that the objects to be included in the exhibition ``The Original Copy: Photography...

  14. 77 FR 2340 - Culturally Significant Objects Imported for Exhibition Determinations: “Snapshot: Painters and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Snapshot: Painters and Photography... Photography, Bonnard to Vuillard'' imported from abroad for temporary exhibition within the United States,...

  15. 77 FR 50542 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2012...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2012: Michele Abeles... objects to be included in the exhibition ``New Photography 2012: Michele Abeles, Birdhead (Ji Weiyu...

  16. 78 FR 40544 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2013...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2013: Adam Broomberg..., 2003), I hereby determine that the objects to be included in the exhibition ``New Photography...

  17. 77 FR 48198 - Culturally Significant Objects Imported for Exhibition Determinations: “Faking It: Manipulated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Faking It: Manipulated Photography... Photography Before Photoshop,'' imported from abroad for temporary exhibition within the United States, are...

  18. 76 FR 58075 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt and Degas: Two...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rembrandt and Degas: Two Young... Young Artists,'' imported from abroad for temporary exhibition within the United States, are of...

  19. 77 FR 22376 - Culturally Significant Objects Imported for Exhibition Determinations: “Ellsworth Kelly: Plant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ellsworth Kelly: Plant Drawings... Kelly: Plant Drawings,'' imported from abroad for temporary exhibition within the United States, is...

  20. 78 FR 12134 - Culturally Significant Objects Imported for Exhibition Determinations: “Temple and Tomb...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Temple and Tomb: Prehistoric Malta... determine that the objects to be included in the exhibition ``Temple and Tomb: Prehistoric Malta,''...

  1. 77 FR 61468 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Balthus: Cats and Girls'' SUMMARY... objects to be included in the exhibition ``Balthus: Cats and Girls,'' imported from abroad for...

  2. 75 FR 25031 - Culturally Significant Objects Imported for Exhibition Determinations: “Tiffany: Color and Light”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tiffany: Color and Light'' SUMMARY... included in the exhibition ``Tiffany: Color and Light,'' imported from abroad for temporary...

  3. 77 FR 65245 - Culturally Significant Objects Imported for Exhibition Determinations: “Portrait of Spain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Portrait of Spain: Masterpieces From..., 2003), I hereby determine that the objects to be included in the exhibition ``Portrait of...

  4. 76 FR 16851 - Culturally Significant Objects Imported for Exhibition Determinations: “Seeing Gertrude Stein...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Seeing Gertrude Stein: Five Stories... Gertrude Stein: Five Stories,'' imported from abroad for temporary exhibition within the United States,...

  5. 76 FR 53524 - Culturally Significant Objects Imported for Exhibition Determinations: “Once Upon Many Times...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Once Upon Many Times: Legends and... Times: Legends and Myths in Himalayan Art,'' imported from abroad for temporary exhibition within...

  6. 78 FR 19062 - Culturally Significant Objects Imported for Exhibition Determinations: “Hans Richter: Encounters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hans Richter: Encounters'' ACTION... ``Hans Richter: Encounters.'' The referenced notice is corrected to accommodate an additional object to... to be included in the exhibition ``Hans Richter: Encounters,'' imported from abroad for...

  7. 78 FR 15802 - Culturally Significant Objects Imported for Exhibition Determinations: “Hans Richter: Encounters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Hans Richter: Encounters'' SUMMARY... objects to be included in the exhibition ``Hans Richter: Encounters,'' imported from abroad for...

  8. 78 FR 79058 - Culturally Significant Objects Imported for Exhibition Determinations: “Chinese Paintings from...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chinese Paintings from Japanese... Japanese Collections,'' imported from abroad for temporary exhibition within the United States, are...

  9. 75 FR 82128 - Culturally Significant Objects Imported for Exhibition Determinations: “Vishnu: Hinduism's Blue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Vishnu: Hinduism's Blue-Skinned... ``Vishnu: Hinduism's Blue-Skinned Savior,'' imported from abroad for temporary exhibition within the...

  10. 78 FR 51802 - Culturally Significant Objects Imported for Exhibition Determinations: “Silla: Korea's Golden...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Silla: Korea's Golden Kingdom... determine that the objects to be included in the exhibition ``Silla: Korea's Golden Kingdom,'' imported...

  11. 78 FR 27276 - Culturally Significant Object Imported for Exhibition Determinations: “Goya's Two Hares”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Goya's Two Hares'' SUMMARY: Notice is... object to be included in the exhibition ``Goya's Two Hares,'' imported from abroad for...

  12. 76 FR 2439 - Culturally Significant Objects Imported for Exhibition Determinations: “Cézanne's Card Players”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``C zanne's Card Players'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``C zanne's Card...

  13. 77 FR 39319 - Culturally Significant Objects Imported for Exhibition Determinations: “Bodies and Shadows...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bodies and Shadows: Caravaggio and..., 2003), I hereby determine that the objects to be included in the exhibition ``Bodies and...

  14. 78 FR 52997 - Culturally Significant Objects Imported for Exhibition Determinations: “Yoga: the Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Yoga: the Art of Transformation... determine that the objects to be included in the exhibition ``Yoga: the Art of Transformation,''...

  15. 75 FR 53012 - Culturally Significant Object Imported for Exhibition Determinations: “Ivory Mirror Case”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Ivory Mirror Case'' SUMMARY: Notice..., I hereby determine that the object to be included in the exhibition ``Ivory Mirror Case,''...

  16. 76 FR 59182 - Culturally Significant Objects Imported for Exhibition Determinations: “Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Impressionism: Masterworks on Paper... determine that the objects to be included in the exhibition ``Impressionism: Masterworks on Paper''...

  17. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Poetry in Clay: Korean...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Poetry in Clay: Korean Buncheong... objects to be included in the exhibition ``Poetry in Clay: Korean Buncheong Ceramics from the...

  18. 77 FR 48199 - Culturally Significant Objects Imported for Exhibition Determinations: “Bernini: Sculpting in Clay”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bernini: Sculpting in Clay'' SUMMARY... objects to be included in the exhibition ``Bernini: Sculpting in Clay,'' imported from abroad...

  19. 77 FR 34121 - Culturally Significant Objects Imported for Exhibition Determinations: “Lucian Freud: Portraits”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Lucian Freud: Portraits'' SUMMARY... object to be included in the exhibition ``Lucian Freud: Portraits,'' imported from abroad by The...

  20. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Federico Barocci...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Federico Barocci: Renaissance Master... determine that the objects to be included in the exhibition ``Federico Barocci: Renaissance...

  1. 76 FR 60113 - Culturally Significant Objects Imported for Exhibition Determinations: “Masters of Venice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Masters of Venice: Renaissance... included in the exhibition ``Masters of Venice: Renaissance Paintings of Passion and Power...

  2. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Charlotte Salomon: Life...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Charlotte Salomon: Life? Or Theatre... Salomon: Life? Or Theatre?'' imported from abroad for temporary exhibition within the United States,...

  3. 76 FR 23642 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 95: Runa Islam”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Projects 95: Runa Islam'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Projects 95: Runa...

  4. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso's Drawings, 1890...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso's Drawings, 1890-1921...-1921: Reinventing Tradition,'' imported from abroad for temporary exhibition within the United...

  5. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “Birth of Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Birth of Impressionism: Masterpieces... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Birth...

  6. 75 FR 3272 - Culturally Significant Objects Imported for Exhibition Determinations: “The Sacred Made Real...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Sacred Made Real: Spanish... Real: Spanish Painting and Sculpture 1600-1700,'' imported from abroad for temporary exhibition...

  7. 75 FR 62916 - Culturally Significant Objects Imported for Exhibition Determinations: “India's Fabled City: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``India's Fabled City: The Art of... ``India's Fabled City: The Art of Courtly Lucknow,'' imported from abroad for temporary exhibition...

  8. 76 FR 77299 - Culturally Significant Objects Imported for Exhibition Determinations: “Civic Pride: Group...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Civic Pride: Group Portraits from..., 2003), I hereby determine that the objects to be included in the exhibition ``Civic Pride:...

  9. 78 FR 8682 - Culturally Significant Object Imported for Exhibition Determinations: “Vermeer's Woman in Blue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Vermeer's Woman in Blue Reading a... ``Vermeer's Woman in Blue Reading a Letter,'' imported from abroad for temporary exhibition within...

  10. 78 FR 24288 - Culturally Significant Objects Imported for Exhibition Determinations: “Frida Kahlo, Diego Rivera...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Frida Kahlo, Diego Rivera, and... included in the exhibition ``Frida Kahlo, Diego Rivera, and Masterpieces of Modern Mexico: The Jacques...

  11. 75 FR 51518 - Culturally Significant Objects Imported for Exhibition Determinations: “Ballplayers, Gods, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ballplayers, Gods, and Rainmaker... objects to be included in the exhibition ``Ballplayers, Gods, and Rainmaker Kings: Masterpieces...

  12. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Johan Zoffany RA: Society...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Johan Zoffany RA: Society Observed... determine that the objects to be included in the exhibition ``Johan Zoffany RA: Society Observed,''...

  13. 75 FR 82127 - Culturally Significant Objects Imported for Exhibition Determinations: “Gauguin: Maker of Myth”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gauguin: Maker of Myth'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Gauguin: Maker of...

  14. 77 FR 60004 - Culturally Significant Object Imported for Exhibition Determinations: “Wtewael's Adam and Eve”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Wtewael's Adam and Eve'' SUMMARY... object to be included in the exhibition ``Wtewael's Adam and Eve,'' imported from abroad for...

  15. 77 FR 6168 - Culturally Significant Objects Imported for Exhibition Determinations: “John Chamberlain: Choices”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``John Chamberlain: Choices'' SUMMARY... objects to be included in the exhibition ``John Chamberlain: Choices,'' imported from abroad for...

  16. 78 FR 48925 - Culturally Significant Object Imported for Exhibition Determinations: “Violence and Virtue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Violence and Virtue: Artemisia... April 15, 2003), I hereby determine that the object to be included in the exhibition ``Violence...

  17. 78 FR 28274 - Culturally Significant Object Imported for Exhibition Determinations: “1763: A Revolutionary Peace”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... temporary exhibition within the United States, is of cultural significance. The object is imported pursuant... display of the exhibit object at the Old State House Museum, Boston, Massachusetts, from on or about...

  18. 76 FR 14115 - Culturally Significant Objects Imported for Exhibition Determinations: “Assorted Greek and Roman...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Assorted Greek and Roman Objects... Greek and Roman Objects'' imported from abroad for temporary exhibition within the United States, are...

  19. 76 FR 7893 - Culturally Significant Objects Imported for Exhibition Determinations: “Neoclassicism: A Taste...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Neoclassicism: A Taste for the... ``Neoclassicism: A Taste for the Antique,'' imported from abroad for temporary exhibition within the United...

  20. 78 FR 71022 - Culturally Significant Objects Imported for Exhibition Determinations: “Christopher Williams: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Christopher Williams: The Production..., 2003), I hereby determine that the objects to be included in the exhibition ``Christopher Williams:...

  1. 76 FR 1660 - Culturally Significant Objects Imported for Exhibition Determinations: “Art in Cameroon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Art in Cameroon: Sculptural... ``Art in Cameroon: Sculptural Dialogues,'' imported from abroad for temporary exhibition within...

  2. 76 FR 38452 - Culturally Significant Object Imported for Exhibition Determinations: “King Amenemhet II”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``King Amenemhet II'' SUMMARY: Notice..., I hereby determine that the object to be included in the exhibition ``King Amenemhet II,''...

  3. 77 FR 23318 - Culturally Significant Object Imported for Exhibition Determinations: “African Cosmos: Stellar Arts”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``African Cosmos: Stellar Arts... Cosmos: Stellar Arts,'' imported from abroad for temporary exhibition within the United States, is...

  4. 77 FR 320 - Culturally Significant Objects Imported for Exhibition Determinations: “Gauguin and Polynesia: An...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gauguin and Polynesia: An Elusive... Elusive Paradise,'' imported from abroad for temporary exhibition within the United States, are...

  5. 75 FR 38589 - Culturally Significant Objects Imported for Exhibition Determinations: “Salvador Dali: The Late...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Salvador Dali: The Late Work... that the objects to be ] included in the exhibition ``Salvador Dali: The Late Work,'' imported...

  6. 75 FR 8424 - Culturally Significant Objects Imported for Exhibition Determinations: “Leaves From an Austrian...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Leaves From an Austrian Mahzor... that the objects to be included in the exhibition ``Leaves from an Austrian Mahzor,'' imported...

  7. 76 FR 65558 - Culturally Significant Objects Imported for Exhibition Determinations: “Masterpieces of Landscape...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Masterpieces of Landscape Painting... Landscape Painting from the Forbidden City'' imported from abroad for temporary exhibition within the...

  8. 75 FR 47337 - Culturally Significant Objects Imported for Exhibition Determinations: “German Impressionist...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``German Impressionist Landscape... the exhibition ``German Impressionist Landscape Painting: Liebermann--Corinth--Slevogt,''...

  9. 75 FR 45194 - Culturally Significant Objects Imported for Exhibition Determinations: “Drawing from Nature...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Drawing from Nature: Landscapes by... objects to be included in the exhibition ``Drawing from Nature: Landscapes by Max Liebermann,...

  10. 78 FR 45285 - Culturally Significant Objects Imported for Exhibition Determinations: “Egypt's Mysterious Book...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Egypt's Mysterious Book of the..., 2003), I hereby determine that the objects to be included in the exhibition ``Egypt's Mysterious...

  11. 78 FR 20372 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' SUMMARY... objects to be included in the exhibition ``Hall of Ancient Egypt,'' imported from abroad for...

  12. 78 FR 1916 - Culturally Significant Objects Imported for Exhibition; Determinations: “Impressionism, Fashion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Impressionism, Fashion, and..., 2003), I hereby determine that the objects to be included in the exhibition ``Impressionism,...

  13. 75 FR 8425 - Culturally Significant Objects Imported for Exhibition Determinations: “Masterpieces of European...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Masterpieces of European Painting... European Painting from Dulwich Picture Gallery,'' imported from abroad for temporary exhibition within...

  14. 78 FR 23623 - Culturally Significant Objects Imported for Exhibition Determinations: “American Encounters...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``American Encounters: Genre Painting...: Genre Painting and Everyday Life,'' imported from abroad for temporary exhibition within the...

  15. 78 FR 17744 - Culturally Significant Objects Imported for Exhibition Determinations: “Maya: Hidden Worlds...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Maya: Hidden Worlds Revealed... determine that the objects to be included in the exhibition ``Maya: Hidden Worlds Revealed,'' imported...

  16. 77 FR 4614 - Culturally Significant Objects Imported for Exhibition Determinations: “Children of the Plumed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Children of the Plumed Serpent: The... exhibition ``Children of the Plumed Serpent: The Legacy of Quetzalcoatl in Ancient Mexico,'' imported...

  17. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Tombs, Temples and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tombs, Temples and Warriors: China's..., 2003), I hereby determine that the objects to be included in the exhibition ``Tombs, Temples...

  18. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Kurt Schwitters: Color...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Kurt Schwitters: Color and Collage... Schwitters: Color and Collage,'' imported from abroad for temporary exhibition within the United States,...

  19. 78 FR 4972 - Culturally Significant Objects Imported for Exhibition Determinations: “Chagall: Beyond Color”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chagall: Beyond Color'' SUMMARY... objects to be included in the exhibition ``Chagall: Beyond Color,'' imported from abroad for...

  20. 77 FR 41473 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 98: Slavs and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Projects 98: Slavs and Tartars... determine that the objects to be included in the exhibition ``Projects 98: Slavs and Tartars,''...

  1. 76 FR 20802 - Culturally Significant Object Imported for Exhibition Determinations: “The Capitoline Venus”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``The Capitoline Venus'' SUMMARY..., I hereby determine that the object to be included in the exhibition ``The Capitoline...

  2. 76 FR 4987 - Culturally Significant Objects Imported for Exhibition Determinations: “Treasures From the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Treasures From the Hermitage: Russia... ``Treasures from the Hermitage: Russia's Crown Jewels,'' imported from abroad for temporary exhibition...

  3. 78 FR 26682 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' AGENCY... additional objects as part of the exhibition. Notice is hereby given of the following determinations... April 15, 2003), I hereby determine that the additional objects to be included in the exhibition...

  4. 77 FR 22833 - Culturally Significant Objects Imported for Exhibition Determinations: “Edouard Vuillard: A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Edouard Vuillard: A Painter and His... pertaining to the exhibit ``Edouard Vuillard: A Painter and His Muses, 1890-1940.'' The reference notice is... exhibition ``Edouard Vuillard: A Painter and His Muses, 1890-1940,'' imported from abroad for...

  5. 75 FR 41274 - Culturally Significant Objects Imported for Exhibition Determinations: “The World of Khubilai...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The World of Khubilai Khan: Chinese... Department of State pertaining to the exhibit ``From Xanadu to Dadu: The World of Khubilai Khan.'' The... exhibit name is now titled, ``The World of Khubilai Khan: Chinese Art in the Yuan Dynasty.'' Pursuant...

  6. 77 FR 4858 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... determinations made by ] the Department of State pertaining to the exhibition ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  7. 77 FR 67725 - Culturally Significant Object Imported for Exhibition Determinations: “Michelangelo's David Apollo”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Michelangelo's David Apollo'' SUMMARY... object to be included in the exhibition ``Michelangelo's David Apollo,'' imported from abroad for... display of the exhibit object at the National Gallery of Art, Washington, DC, from on or about December...

  8. 76 FR 5236 - Culturally Significant Objects Imported for Exhibition Determinations: “Upside Down Arctic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Upside Down Arctic Realities... Down Arctic Realities,'' imported from abroad for temporary exhibition within the United States, are of... additional exhibitions or venues yet to be determined, is in the national interest. I have ordered...

  9. 75 FR 59781 - Culturally Significant Objects Imported for Exhibition Determinations: “Imagining the Past in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Imagining the Past in France, 1250... Authority No. 236-3 of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Imagining the Past in France, 1250-1500,'' imported from abroad for temporary exhibition within the...

  10. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Artifacts From Auschwitz...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Artifacts From Auschwitz-Birkenau... of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Artifacts... of cultural significance. The objects are imported pursuant to a loan agreement with the...

  11. 75 FR 66419 - Culturally Significant Objects Imported for Exhibition Determinations: “Object of Devotion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Object of Devotion: Medieval English... objects to be included in the exhibition ``Object of Devotion: Medieval English Alabaster Sculpture from... States, are of cultural significance. The objects are imported pursuant to loan agreements with...

  12. 77 FR 32711 - Culturally Significant Objects Imported for Exhibition Determinations: “Messerschmidt and Modernity”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Messerschmidt and Modernity...-3 of August 28, 2000, I hereby determine that the objects to be included in the exhibition... cultural significance. The objects are imported pursuant to loan agreements with the foreign owners...

  13. 77 FR 26353 - Culturally Significant Objects Imported for Exhibition Determinations: “Lygia Clark”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Lygia Clark'' SUMMARY: Notice is... objects to be imported from abroad for temporary study and inclusion in the exhibition ``Lygia Clark,'' within the United States, are of cultural significance. The objects are imported pursuant to...

  14. Middle-aged adults exhibit altered spatial variations in Achilles tendon wave speed

    PubMed Central

    Slane, Laura Chernak; DeWall, Ryan; Martin, Jack; Lee, Kenneth; Thelen, Darryl G.

    2016-01-01

    The purpose of this study was to investigate spatial variations in measured wave speed in the relaxed and stretched Achilles tendons of young and middle-aged adults. Wave speed was measured from the distal Achilles tendon, soleus aponeurosis, medial gastrocnemius aponeurosis and medial gastrocnemius muscle in healthy young (n = 15, aged 25 ± 4 years) and middle-aged (n = 10, aged 49 ± 4 years) adults in resting, dorsiflexed and plantarflexed postures. In both age groups, Achilles tendon wave speed decreased proximally, with the lowest wave speed measured in the gastrocnemius aponeurosis. Measured wave speed increased with passive dorsiflexion, reflecting the strain-stiffening behavior of tendons. There were no significant aging effects on wave speed in the free tendon or soleus aponeurosis. However, a significant, inverse relationship between gastrocnemius aponeurosis wave speed and age was observed in the dorsiflexed posture. We also observed significantly lower wave speeds in the gastrocnemius muscles of middle-aged adults when compared with young adults. These results suggest that Achilles tendon compliance increases in a distal-to-proximal pattern, with middle-aged adults exhibiting greater compliance in the distal gastrocnemius muscle and tendinous structures. An age-related change in the spatial variation in Achilles tendon compliance could affect localised tissue deformation patterns and injury potential within the triceps surae muscle-tendon units. PMID:26020294

  15. 78 FR 79560 - Culturally Significant Objects Imported for Exhibition Determinations: “Khirbet el-Maqatir...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ..., ``Khirbet el-Maqatir: History of a Biblical Site,'' imported from abroad for temporary exhibition within the... Culturally Significant Objects Imported for Exhibition Determinations: ``Khirbet el-Maqatir: History of a Biblical Site'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...

  16. 75 FR 61238 - Culturally Significant Objects Imported for Exhibition Determinations: “Expanding the Story With...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Expanding the Story With Four Greek... ``Expanding the Story with Four Greek Vases,'' imported from abroad for temporary exhibition within the...

  17. 77 FR 36329 - Culturally Significant Objects Imported for Exhibition Determinations: “Dead Sea Scrolls & The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Dead Sea Scrolls & The Bible Ancient Artifacts-- Timeless Treasures'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Dead Sea...

  18. 76 FR 39974 - Culturally Significant Objects Imported for Exhibition Determinations: “Warhol: The Headlines”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Warhol: The Headlines'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Warhol: The Headlines... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  19. 76 FR 14115 - Culturally Significant Objects Imported for Exhibition Determinations: “Cross References”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Cross References'' Summary: Notice..., I hereby determine that the objects to be included in the exhibition ``Cross References'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  20. 75 FR 47338 - Culturally Significant Objects Imported for Exhibition Determinations: “Franz Xaver Messerschmidt”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Franz Xaver Messerschmidt'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Franz Xaver Messerschmidt... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  1. 76 FR 12399 - Culturally Significant Objects Imported for Exhibition Determinations: “Paris: Life & Luxury”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Paris: Life & Luxury'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Paris: Life & Luxury... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  2. 76 FR 29286 - Culturally Significant Objects Imported for Exhibition Determinations: “Pissarro's People”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Pissarro's People'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Pissarro's People,'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  3. 78 FR 61948 - Culturally Significant Objects Imported for Exhibition Determinations: “Franz von Stuck”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Franz von Stuck'' SUMMARY: Notice is..., I hereby determine that the objects to be included in the exhibition ``Franz von Stuck,'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  4. 77 FR 46554 - Culturally Significant Objects Imported for Exhibition Determinations: “Nicolai Fechin”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Nicolai Fechin'' AGENCY: Department... additional objects as part of the exhibition. Notice is hereby given of the following determinations... Delegation of Authority No. 236-3 of August 28, 2000, I hereby determine that the additional objects to...

  5. 76 FR 73760 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Holocaust'' SUMMARY: Notice is..., I hereby determine that the objects to be included in the exhibition ``The Holocaust,'' imported... objects are imported pursuant to a loan agreement with the foreign owner or custodian. I also...

  6. 76 FR 6650 - Culturally Significant Objects Imported for Exhibition Determinations: “Heinrich Kühn”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Heinrich K hn'' SUMMARY: Notice is..., I hereby determine that the objects to be included in the exhibition ``Heinrich K hn,'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  7. 78 FR 4972 - Culturally Significant Objects Imported for Exhibition Determinations: “Nicolai Fechin”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Nicolai Fechin'' AGENCY: Department... additional objects as part of the exhibition. Notice is hereby given of the following determinations... April 15, 2003), I hereby determine that the additional objects to be included in the...

  8. 78 FR 56766 - Culturally Significant Objects Imported for Exhibition Determinations: “Antonio Berni: Juanito...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Antonio Berni: Juanito and Ramona... determine that the objects to be included in the exhibition ``Antonio Berni: Juanito and Ramona,'' imported... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  9. 77 FR 17104 - Culturally Significant Objects Imported for Exhibition Determinations: “Ecstatic Alphabets/Heaps...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Ecstatic Alphabets/Heaps of Language... determine that the objects to be included in the exhibition ``Ecstatic Alphabets/Heaps of Language... these Determinations be published in the Federal Register. FOR FURTHER INFORMATION CONTACT: For...

  10. 78 FR 53817 - Culturally Significant Objects Imported for Exhibition Determinations: “Venetian Glass by Carlo...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Venetian Glass by Carlo Scarpa: The... April 15, 2003, I hereby determine that the objects to be included in the exhibition ``Venetian Glass...

  11. 75 FR 13806 - Culturally Significant Objects Imported for Exhibition Determinations: “Loan From the Aura...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Loan From the Aura Collection of a... hereby determine that the object to be included in the exhibition ``Loan from the Aura Collection of...

  12. 76 FR 53524 - Culturally Significant Objects Imported for Exhibition Determinations: “Light Years: Conceptual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Light Years: Conceptual Art and the..., 2003), I hereby determine that the objects to be included in the exhibition ``Light Years:...

  13. 77 FR 60506 - Culturally Significant Objects Imported for Exhibition Determinations: “Light and Shadows: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Light and Shadows: The Story of..., 2003), I hereby determine that certain of the objects to be included in the exhibition ``Light...

  14. 75 FR 18252 - Culturally Significant Object Imported for Exhibition Determinations: “Through African Eyes: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Through African Eyes: The European in... 15, 2003 , I hereby determine that the object to be included in the exhibition ``Through African...

  15. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Adapting the Eye: An...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Adapting the Eye: An Archive of the... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Adapting the...

  16. 76 FR 36166 - Culturally Significant Objects Imported for Exhibition; Determinations: “Gabriel von Max: Be...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Gabriel von Max: Be-Tailed Cousins... the exhibition ``Gabriel von Max: Be-Tailed Cousins and Phantasms of the Soul,'' imported from...

  17. 75 FR 37521 - Culturally Significant Objects Imported for Exhibition Determinations: “Eton College Myers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Eton College Myers Collection at... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Eton College...

  18. 77 FR 22630 - Culturally Significant Objects Imported for Exhibition Determinations: “The Printed Image in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Printed Image in China, 8th-21st... ``The Printed Image in China, 8th-21st Century,'' imported from abroad for temporary exhibition...

  19. 76 FR 56865 - Culturally Significant Objects Imported for Exhibition Determinations: “Degas and the Nude”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Degas and the Nude'' SUMMARY: Notice... objects to be included in the exhibition ``Degas and the Nude,'' imported from abroad for...

  20. 77 FR 2603 - Culturally Significant Objects Imported for Exhibition Determinations: “Princes and Painters in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Princes and Painters in Mughal Delhi..., 2003), I hereby determine that the objects to be included in the exhibition ``Princes and Painters...

  1. 77 FR 21142 - Culturally Significant Objects Imported for Exhibition Determinations: “Edouard Vuillard: A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Edouard Vuillard: A Painter and His... Painter and His Muses, 1890-1940,'' imported from abroad for temporary exhibition within the United...

  2. 75 FR 21385 - Culturally Significant Objects Imported for Exhibition Determinations: “Cleopatra: The Search for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Cleopatra: The Search for the Last... hereby determine that the objects to be included in the exhibition ``Cleopatra: The Search for the...

  3. 77 FR 61468 - Culturally Significant Objects Imported for Exhibition Determinations: “Matisse: In Search of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Matisse: In Search of True Painting... determine that the objects to be included in the exhibition ``Matisse: In Search of True...

  4. 78 FR 45286 - Culturally Significant Objects Imported for Exhibition Determinations: “Canterbury and St. Albans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Canterbury and St. Albans: Treasures... St. Albans: Treasures from Church and Cloister,'' imported from abroad for temporary exhibition... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: July 22, 2013. Ann...

  5. 79 FR 61125 - Culturally Significant Object Imported for Exhibition Determinations: “Delacroix's Greece on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2014-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Delacroix's Greece on the Ruins of..., 2003), I hereby determine that the object to be included in the exhibition ``Delacroix's Greece on...

  6. 76 FR 60112 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  7. 76 FR 5236 - Culturally Significant Objects Imported for Exhibition Determinations: “Pastel Portraits: Images...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Pastel Portraits: Images of 18th... ``Pastel Portraits: Images of 18th-Century Europe,'' imported from abroad for temporary exhibition...

  8. 75 FR 82128 - Culturally Significant Objects Imported for Exhibition Determinations: “The Orient Expressed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Orient Expressed: Japan's... the exhibition ``The Orient Expressed: Japan's Influence on Western Art, 1854-1918,'' imported from... or about February 19, 2011, until on or about July 17, 2011, the McNay Art Museum, San Antonio,...

  9. 75 FR 15764 - Culturally Significant Objects Imported for Exhibition Determinations: “Gods of Angkor: Bronzes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gods of Angkor: Bronzes From the... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Gods of...

  10. 77 FR 46146 - Culturally Significant Objects Imported for Exhibition Determinations: “Shock of the News”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Shock of the News'' SUMMARY: Notice... objects to be included in the exhibition ``Shock of the News,'' imported from abroad for...

  11. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Anglo-Saxon Hoard: Gold...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Anglo-Saxon Hoard: Gold From England..., 2003), I hereby determine that the objects to be included in the exhibition ``Anglo-Saxon Hoard:...

  12. 77 FR 25780 - Culturally Significant Objects Imported for Exhibition Determinations: “Gold, Jasper, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gold, Jasper, and Carnelian: Johann... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Gold,...

  13. 78 FR 59080 - Culturally Significant Objects Imported for Exhibition Determinations: “Delacroix and the Matter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Delacroix and the Matter of Finish... determine that the objects to be included in the exhibition ``Delacroix and the Matter of Finish,''...

  14. 77 FR 65245 - Culturally Significant Objects Imported for Exhibition Determinations: “Late Roman and Early...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Late Roman and Early Byzantine... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Late Roman...

  15. 78 FR 27470 - Culturally Significant Objects Imported for Exhibition Determinations: “Shaping Power: Luba...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Shaping Power: Luba Masterworks From... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Shaping...

  16. 77 FR 56251 - Culturally Significant Objects Imported for Exhibition Determinations: “The Body Beautiful in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Body Beautiful in Ancient Greece... determine that the objects to be included in the exhibition ``The Body Beautiful in Ancient...

  17. 77 FR 28419 - Culturally Significant Objects Imported for Exhibition Determinations: “Gustav Klimt: The Magic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gustav Klimt: The Magic of Line... determine that the objects to be included in the exhibition ``Gustav Klimt: The Magic of Line,''...

  18. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition Determinations: “Chagall: Love, War, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chagall: Love, War, and Exile... determine that the objects to be included in the exhibition ``Chagall: Love, War, and Exile,'' imported...

  19. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “The Aztec Pantheon and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Aztec Pantheon and the Art... hereby determine that the objects to be included in the exhibition ``The Aztec Pantheon and the...

  20. 75 FR 1110 - Culturally Significant Objects Imported for Exhibition Determinations: “Marina Abramovic: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Marina Abramovic: The Artist Is Present'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... hereby determine that the objects to be included in the exhibition ``Marina Abramovic: The Artist...

  1. 78 FR 71021 - Culturally Significant Objects Imported for Exhibition Determinations: “Antonio Canova: The Seven...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Antonio Canova: The Seven Last Works... determine that the objects to be included in the exhibition ``Antonio Canova: The Seven Last...

  2. 76 FR 56864 - Culturally Significant Objects Imported for Exhibition Determinations: “Caravaggio and His...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Caravaggio and His Followers in Rome... determine that the objects to be included in the exhibition ``Caravaggio and His Followers in...

  3. 77 FR 53959 - Culturally Significant Object Imported for Exhibition Determinations: “Dancing Into Dreams, Maya...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Dancing Into Dreams, Maya Vases From..., 2003), I hereby determine that the object to be included in the exhibition ``Dancing Into Dreams,...

  4. 75 FR 3781 - Culturally Significant Objects Imported for Exhibition Determinations: “The Mourners: Tomb...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Mourners: Tomb Sculptures From... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``The Mourners:...

  5. 77 FR 62311 - Culturally Significant Objects Imported for Exhibition Determinations: “Royal Treasures From the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-12

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Royal Treasures From the Louvre... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Royal...

  6. 77 FR 37730 - Culturally Significant Objects Imported for Exhibition Determinations: “Nomads and Networks: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Nomads and Networks: The Ancient Art... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Nomads...

  7. 77 FR 7229 - Culturally Significant Objects Imported for Exhibition Determinations: “Nomads and Networks: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Nomads and Networks: The Ancient Art... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Nomads...

  8. 78 FR 51803 - Culturally Significant Objects Imported for Exhibition Determinations: “Vasily Kandinsky: From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Vasily Kandinsky: From Blaue Reiter... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Vasily...

  9. 76 FR 18291 - Culturally Significant Objects Imported for Exhibition Determinations: “Boris Mikhailov: Case...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Boris Mikhailov: Case History... Mikhailov: Case History,'' imported from abroad for temporary exhibition within the United States, are of... Art, New York, New York, from on or about May 26, 2011, until on or about September 5, 2011, and...

  10. 77 FR 34455 - Culturally Significant Objects Imported for Exhibition Determinations: “Century of the Child...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Century of the Child: Growing by Design 1900-2000'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the..., 2003), I hereby determine that the objects to be included in the exhibition ``Century of the...

  11. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Diego Rivera: Murals for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Diego Rivera: Murals for the Museum..., 2003), I hereby determine that the objects to be included in the exhibition ``Diego Rivera: Murals...

  12. 75 FR 39724 - Culturally Significant Objects Imported for Exhibition Determinations: “Arcimboldo (1526-1593...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Arcimboldo (1526-1593): Nature and... hereby determine that the objects to be included in the exhibition ``Arcimboldo (1526-1593): Nature...

  13. 77 FR 38881 - Culturally Significant Objects Imported for Exhibition Determinations: “Regarding Warhol: Sixty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ...; then at the Andy Warhol Museum in Pittsburgh, Pennsylvania from on or about February 2, 2013 to on or... Culturally Significant Objects Imported for Exhibition Determinations: ``Regarding Warhol: Sixty Artists..., 2003), I hereby determine that the objects to be included in the exhibition ``Regarding Warhol:...

  14. 76 FR 77299 - Culturally Significant Objects Imported for Exhibition Determinations: “Van Gogh. Up Close”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Van Gogh. Up Close'' SUMMARY: Notice... objects to be included in the exhibition ``Van Gogh. Up Close.,'' imported from abroad for...

  15. 76 FR 15358 - Culturally Significant Objects Imported for Exhibition Determinations: “Before the Pyramids: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Before the Pyramids: The Origins of... ``Before the Pyramids: The Origins of Egyptian Civilization'' imported from abroad for temporary...

  16. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Balthus: Cats and Girls--Paintings... ``Balthus: Cats and Girls--Paintings and Provocations,'' imported from abroad for temporary...

  17. 78 FR 8682 - Culturally Significant Objects Imported for Exhibition Determinations: “Henri Labrouste...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Henri Labrouste: Structure Brought to Light'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...

  18. 76 FR 23642 - Culturally Significant Objects Imported for Exhibition Determinations: “Marajo: Ancient Ceramics...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Marajo: Ancient Ceramics at the... ``Marajo: Ancient Ceramics at the Mouth of the Amazon'' imported from abroad for temporary...

  19. 75 FR 52385 - Culturally Significant Objects Imported for Exhibition Determinations: “Paintings From the Reign...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    .... Correction In the Federal Register of August 26, 2008, in FR volume 73, page 50395, at the end of the..., concerning culturally significant objects imported for exhibition determinations. The document did not...

  20. 76 FR 70805 - Culturally Significant Objects Imported for Exhibition Determinations: “The Renaissance Portrait...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Renaissance Portrait From... ``The Renaissance Portrait from Donatello to Bellini,'' imported from abroad for temporary...

  1. 77 FR 38374 - Culturally Significant Objects Imported for Exhibition Determinations: “The Human Beast: German...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Human Beast: German...: German Expressionism at The San Diego Museum of Art'' imported from abroad for temporary...

  2. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Dancing Around the Bride...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Dancing Around the Bride: Cage... ``Dancing Around the Bride: Cage, Cunningham, Johns, Rauschenberg, and Duchamp,'' imported from abroad...

  3. 75 FR 5637 - Culturally Significant Objects Imported for Exhibition Determinations: “Architecture as Icon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Architecture as Icon: Perception and... Icon: Perception and Representation of Architecture in Byzantine Art,'' imported from abroad...

  4. 77 FR 28923 - Culturally Significant Objects Imported for Exhibition Determinations: “Unearthed: Recent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Unearthed: Recent Archeological...: Recent Archeological Discoveries from Northern China,'' imported from abroad for temporary...

  5. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Holocaust'' SUMMARY: Notice is... amended, and Delegation of Authority No. 257 of April 15, 2003 , I hereby determine that the objects to be... United States, are of cultural significance. The objects are imported pursuant to loan agreements...

  6. 75 FR 7649 - Culturally Significant Objects Imported for Exhibition Determinations: “Otto Dix”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Otto Dix'' SUMMARY: Notice is hereby... amended, and Delegation of Authority No. 257 of April 15, 2003 , I hereby determine that the objects to be... States, are of cultural significance. The objects are imported pursuant to loan agreements with...

  7. 75 FR 1009 - Culturally Significant Objects Imported for Exhibition Determinations: “Habsburg Treasures”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Habsburg Treasures'' SUMMARY: Notice... amended, and Delegation of Authority No. 257 of April 15, 2003 , I hereby determine that the objects to be... United States, are of cultural significance. The objects are imported pursuant to a loan agreement...

  8. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “The Glory of Ukraine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Glory of Ukraine: Sacred Images... Ukraine: Sacred Images from the 11th to the 19th Centuries,'' imported from abroad for...

  9. 76 FR 49832 - Culturally Significant Object Imported for Exhibition Determinations: “Warhol: The Headlines”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Warhol: The Headlines'' ACTION..., ``Warhol: The Headlines.'' The referenced notice is corrected to add one additional object to be included..., Delegation of Authority No. 257 of April 15, 2003), I hereby determine that the additional object to...

  10. 78 FR 55134 - Culturally Significant Object Imported for Exhibition Determinations: “Iran Modern”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Iran Modern'' ACTION: Notice....'' The referenced notice is corrected to accommodate an additional object to be included in the... of Authority No. 257 of April 15, 2003), I hereby determine that the additional object to be...

  11. 77 FR 3320 - Culturally Significant Objects Imported for Exhibition Determinations: “Print/Out”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... [Federal Register Volume 77, Number 14 (Monday, January 23, 2012)] [Notices] [Page 3320] [FR Doc No: 2012-1262] DEPARTMENT OF STATE [Public Notice: 7771] Culturally Significant Objects Imported for... April 15, 2003), I hereby determine that the objects to be included in the exhibition...

  12. 78 FR 51803 - Culturally Significant Objects Imported for Exhibition Determinations: “Charles Marville...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority...: Photographer of Paris,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners...

  13. 75 FR 1680 - Culturally Significant Objects Imported for Exhibition: Determinations: “Giovanni Boldini in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Paris,'' imported from abroad for temporary ] exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners or custodians....

  14. 77 FR 53959 - Culturally Significant Objects Imported for Exhibition Determinations: “Roads of Arabia...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Roads of Arabia: Archaeology and the...: Archaeology and the History of the Kingdom of Saudi Arabia,'' imported from abroad for temporary...

  15. 77 FR 7655 - Culturally Significant Objects Imported for Exhibition Determinations: “Inventing the Modern...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Inventing the Modern World: Decorative Arts at the World's Fairs, 1851-1939'' SUMMARY: Notice is hereby given of the following... ``Inventing the Modern World: Decorative Arts at the World's Fairs, 1851-1939'' imported from abroad...

  16. 76 FR 81004 - Culturally Significant Objects Imported for Exhibition Determinations: “Woman in Blue, Against...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Woman in Blue, Against Blue Water..., 2003), I hereby determine that the object ``Woman in Blue, Against Blue Water'' by Edvard...

  17. 75 FR 17197 - Culturally Significant Objects Imported for Exhibition Determinations: “Cyprus: Crossroads of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... from abroad for temporary exhibition within the United States, are of cultural significance. The... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE... of Natural History, Washington, DC, from on or about September 1, 2010, until on or about April...

  18. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 13 2014-01-01 2013-01-01 true Finding of No Significant Environmental Impact I Exhibit I to Subpart G of Part 1940 Agriculture Regulations of the Department of Agriculture (Continued... AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL...

  19. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Finding of No Significant Environmental Impact I Exhibit I to Subpart G of Part 1940 Agriculture Regulations of the Department of Agriculture (Continued... AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL...

  20. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 13 2012-01-01 2012-01-01 false Finding of No Significant Environmental Impact I Exhibit I to Subpart G of Part 1940 Agriculture Regulations of the Department of Agriculture (Continued... AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL...

  1. 77 FR 41473 - Culturally Significant Objects Imported for Exhibition Determinations: “Lion Attacking a Horse”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Lion Attacking a Horse'' SUMMARY... object entitled ``Lion Attacking a Horse,'' to be imported by The J. Paul Getty Museum from abroad...

  2. Significance of Individuation in Adult Child--Parent Relationships

    ERIC Educational Resources Information Center

    Buhl, Heike M.

    2008-01-01

    This study investigates the significance of adult children's individuation for the adult child--parent relationship. Following Youniss, individuation was assessed via its dimensions of both connectedness and individuality. A sample of 349 participants between 20 and 47 years of age were given questionnaires containing scales from the Network of…

  3. 78 FR 52601 - Culturally Significant Object Imported for Exhibition; Determinations: “Visiting Masterpiece...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... of Art, imported from abroad for temporary exhibition within the United States, is of cultural... determine that the exhibition or display of the exhibit object at the Museum of Fine Arts, Boston, MA,...

  4. 77 FR 65603 - Culturally Significant Objects Imported for Exhibition Determinations: “Inventing Abstraction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... that the exhibition or display of the exhibit objects at the Museum of Modern Art, New York, New York... exhibition or display of one of the objects at the Los Angeles County Museum of Art, Los Angeles,...

  5. 78 FR 52996 - Culturally Significant Objects Imported for Exhibition Determinations: “Face to Face: Flanders...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ..., and Renaissance Painting'' Exhibition SUMMARY: Notice is hereby given of the following determinations...: Flanders, Florence, and Renaissance Painting,'' imported from abroad for temporary exhibition within...

  6. Dynamics of hypersonic flight vehicles exhibiting significant aeroelastic and aeropropulsive interactions

    NASA Technical Reports Server (NTRS)

    Chavez, Frank R.; Schmidt, David K.

    1993-01-01

    With analytic expressions previously developed for the forces and moments acting on a generic hypersonic vehicle, it is of interest to investigate the relative importance of the aerodynamic and propulsive effects on the vehicle dynamics. It is shown that the vehicle's aerodynamics and propulsive forces are both very significant in the evaluation of key stability derivatives which dictate the vehicle's dynamic characteristics. It is also shown that the vehicle model selected is unstable in pitch and exhibits strong airframe/engine/elastic coupling. With the use of literal expressions for both the systems poles and zeros, as well as the stability derivatives, key vehicle dynamic characteristics are investigated. For small errors, or uncertainties, in either the aerodynamic or propulsive forces, significant errors in the frequency and damping of the dominant modes and zero locations will arise.

  7. Self-Concept, Anxiety, and Knowledge Exhibited by Adult Children of Alcoholics and Adult Children of Non Alcoholics.

    ERIC Educational Resources Information Center

    Webb, Wanda; And Others

    1992-01-01

    Compared 59 adult children of alcoholics (ACOAs) and 175 adult children of nonalcoholics (non-ACOAs) on self-concept, anxiety, and their knowledge of ACOA issues. Found no significant differences on self-concept and knowledge of ACOA issues. Significant differences were found on levels of anxiety, such that ACOAs had higher anxiety levels than did…

  8. 75 FR 30459 - Culturally Significant Objects Imported for Exhibition Determinations: “Dynasty and Divinity: Ife...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ... determine that the exhibition or display of the exhibit objects at the Museum of Fine Arts, Houston, TX, from on or about September 19, 2010, until on or about January 9, 2011; at the Virginia Museum of...

  9. 75 FR 8424 - Culturally Significant Objects Imported for Exhibition Determinations: “Matisse: Radical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... that the exhibition or display of the exhibit objects at the Art Institute of Chicago, Chicago, IL, from on or about March 20, 2010, until on or about June 20, 2010; at the Museum of Modern Art, New...

  10. 77 FR 74048 - Culturally Significant Object Imported for Exhibition Determinations: “Connecting Collections...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... Connections. 50 Years of Pre-Columbian Art at Dumbarton Oaks'' SUMMARY: Notice is hereby given of the... exhibition ``Connecting Collections: Collecting Connections. 50 Years of Pre-Columbian Art at Dumbarton Oaks... that the exhibition or display of the exhibit object at Dumbarton Oaks, Washington, DC, from on...

  11. 78 FR 13930 - Culturally Significant Object Imported for Exhibition Determinations: “Portrait of Francesco I d...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Portrait of Francesco I d'Este... determine that the object to be included in the exhibition ``Portrait of Francesco I d'Este,'' imported from abroad for temporary exhibition within the United States, is of cultural significance. The object...

  12. 75 FR 41274 - Culturally Significant Objects Imported for Exhibition Determinations: “The Art of Ancient Greek...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Art of Ancient Greek Theater... Ancient Greek Theater,'' imported from abroad for temporary exhibition within the United States, are...

  13. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Mir : The Dutch...

  14. 75 FR 74126 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Guitars 1912-1914”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso: Guitars 1912-1914'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Picasso: Guitars...

  15. 75 FR 53730 - Culturally Significant Objects Imported for Exhibition Determinations: “Richard Hawkins-Third Mind”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Richard Hawkins--Third Mind... Hawkins--Third Mind,'' imported from abroad for temporary exhibition within the United States, are...

  16. 76 FR 40419 - Culturally Significant Objects Imported for Exhibition Determinations: “Prints and the Pursuit of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Prints and the Pursuit of Knowledge... the exhibition ``Prints and the Pursuit of Knowledge in Early Modern Europe,'' imported from...

  17. 76 FR 58075 - Culturally Significant Objects Imported for Exhibition Determinations: “Sanja Iveković: Sweet...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Sanja Ivekovi : Sweet Violence... determine that the objects to be included in the exhibition ``Sanja Ivekovi : Sweet Violence,''...

  18. 76 FR 58074 - Culturally Significant Objects Imported for Exhibition Determinations: “Sanja Iveković: Sweet...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Sanja Ivekovi : Sweet Violence... determine that the objects to be included in the exhibition ``Sanja Ivekovi : Sweet Violence,''...

  19. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Heaven and Earth: Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Heaven and Earth: Art of Byzantium... the exhibition ``Heaven and Earth: Art of Byzantium from Greek Collections,'' imported from abroad...

  20. 78 FR 79559 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Experience of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Experience of Seeing... determine that the objects to be included in the exhibition ``Mir : The Experience of Seeing,''...

  1. The adaptive significance of adult neurogenesis: an integrative approach

    PubMed Central

    Konefal, Sarah; Elliot, Mick; Crespi, Bernard

    2013-01-01

    Adult neurogenesis in mammals is predominantly restricted to two brain regions, the dentate gyrus (DG) of the hippocampus and the olfactory bulb (OB), suggesting that these two brain regions uniquely share functions that mediate its adaptive significance. Benefits of adult neurogenesis across these two regions appear to converge on increased neuronal and structural plasticity that subserves coding of novel, complex, and fine-grained information, usually with contextual components that include spatial positioning. By contrast, costs of adult neurogenesis appear to center on potential for dysregulation resulting in higher risk of brain cancer or psychological dysfunctions, but such costs have yet to be quantified directly. The three main hypotheses for the proximate functions and adaptive significance of adult neurogenesis, pattern separation, memory consolidation, and olfactory spatial, are not mutually exclusive and can be reconciled into a simple general model amenable to targeted experimental and comparative tests. Comparative analysis of brain region sizes across two major social-ecological groups of primates, gregarious (mainly diurnal haplorhines, visually-oriented, and in large social groups) and solitary (mainly noctural, territorial, and highly reliant on olfaction, as in most rodents) suggest that solitary species, but not gregarious species, show positive associations of population densities and home range sizes with sizes of both the hippocampus and OB, implicating their functions in social-territorial systems mediated by olfactory cues. Integrated analyses of the adaptive significance of adult neurogenesis will benefit from experimental studies motivated and structured by ecologically and socially relevant selective contexts. PMID:23882188

  2. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “Treasures of Heaven...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ..., and Devotion in Medieval Europe'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Treasures of Heaven: Saints, Relics, and Devotion in Medieval Europe,'' imported...

  3. 75 FR 43225 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust-Uniforms...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ..., and Shoes'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``The Holocaust--Uniforms, Canisters, and Shoes,'' imported from abroad for temporary exhibition...

  4. 77 FR 15839 - Culturally Significant Objects Imported for Exhibition Determinations: “Making a Presence: F...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... Artistic Photography'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the.... Holland Day in Artistic Photography,'' imported from abroad for temporary exhibition within the...

  5. 78 FR 55772 - Culturally Significant Objects Imported for Exhibition Determinations: “American Adversaries...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... Copley in a Transatlantic World'' SUMMARY: Notice is hereby given of the following determinations... Adversaries: West and Copley in a Transatlantic World,'' imported from abroad for temporary exhibition...

  6. 76 FR 28499 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso and Braque: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Experiment'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Picasso and Braque: The Cubist Experiment,'' imported from abroad for temporary exhibition within...

  7. 75 FR 43225 - Culturally Significant Objects Imported for Exhibition Determinations: “Man, Myth, and Sensual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ...: Jan Gossart's Renaissance'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... the exhibition ``Man, Myth, and Sensual Pleasures: Jan Gossart's Renaissance,'' imported from...

  8. 76 FR 2438 - Culturally Significant Objects Imported for Exhibition Determinations: “Kings, Queens, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... Early Renaissance France'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``Kings, Queens, and Courtiers: Art in Early Renaissance France'' imported from...

  9. 78 FR 56980 - Culturally Significant Objects Imported for Exhibition Determinations: “Francesco Vanni: Art in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... Renaissance Siena'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Late Renaissance Siena,'' imported from abroad for temporary exhibition within the United States,...

  10. 77 FR 34121 - Culturally Significant Objects Imported for Exhibition Determinations: “Revealing the African...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Renaissance Europe'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Presence in Renaissance Europe'' imported from abroad for temporary exhibition within the United...

  11. 74 FR 44894 - Culturally Significant Objects Imported for Exhibition Determinations: “Heroes: Mortals and Myths...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2009-08-31

    ... Greece'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... hereby determine that the objects in the exhibition: ``Heroes: Mortals and Myths in Ancient...

  12. 75 FR 9013 - Culturally Significant Objects Imported for Exhibition Determinations: “Vienna Circa 1780: An...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Silver Service Rediscovered'' SUMMARY: Notice is hereby given of the following determinations: Pursuant...: An Imperial Silver Service Rediscovered,'' imported from abroad for temporary exhibition within...

  13. 76 FR 28121 - Culturally Significant Objects Imported for Exhibition Determinations: “National Geographic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... Earth'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``National Geographic Treasures of the Earth'' imported from abroad for temporary exhibition within...

  14. 75 FR 60490 - Culturally Significant Objects Imported for Exhibition Determinations: “Haremhab, The General Who...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... King'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Haremhab, The General Who Became King,'' imported from abroad for temporary exhibition within the...

  15. 75 FR 71787 - Culturally Significant Objects Imported for Exhibition Determinations: “Salvator Rosa: Bandits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... and Magic'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Salvator Rosa: Bandits, Wilderness and Magic'', imported from abroad for temporary exhibition within...

  16. 78 FR 51802 - Culturally Significant Objects Imported for Exhibition Determinations: “Robert Motherwell: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Collages'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Early Collages,'' imported from abroad for temporary exhibition within the United States, are...

  17. 78 FR 5556 - Culturally Significant Objects Imported for Exhibition Determinations: “Frida & Diego: Passion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority..., Politics and Painting,'' imported from abroad for temporary exhibition within the United States, are...

  18. 75 FR 47338 - Culturally Significant Objects Imported for Exhibition Determinations: “The Nepalese Legacy in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``The Nepalese Legacy in Tibetan Painting,'' imported from abroad for temporary exhibition within...

  19. 76 FR 58076 - Culturally Significant Objects Imported for Exhibition Determinations: “Maharaja: The Splendor of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... Royal Courts'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... India's Royal Courts,'' imported from abroad for temporary exhibition within the United States, are...

  20. Education for Older Adults: A Synthesis of Significant Data.

    ERIC Educational Resources Information Center

    Ventura-Merkel, Catherine; Worthy, Edmund H., Jr.

    Despite the record numbers of older learners today and the probable future growth of these numbers, older people today are underrepresented in adult education. Furthermore, a significant segment of older people has serious educational deficiencies hindering their ability to cope in the contemporary world. Surveys show that the characteristics that…

  1. 77 FR 64373 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... in Ancient Times,'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times... corrected here to change the exhibition name to ``The Dead Sea Scrolls: Life and Faith in Ancient Times... exhibition ``The Dead Sea Scrolls: Life and Faith in Ancient Times,'' imported from abroad for...

  2. 78 FR 62326 - Culturally Significant Objects Imported for Exhibition Determinations: “Toulouse-Lautrec and La...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-16

    ...: Paris 1880- 1910'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... the exhibition ``Toulouse-Lautrec and La Vie Moderne: Paris 1880-1910,'' imported from abroad for... pursuant to loan agreements with the foreign owners or custodians. I also determine that the exhibition...

  3. 76 FR 71616 - Culturally Significant Objects Imported for Exhibition Determinations: “The Steins Collect...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... temporary display at The Metropolitan Museum of Art, which is nine rather than six. Therefore, I determine that the exhibition or display of all of the exhibit objects at the San Francisco Museum of Modern Art... temporary display of nine of the objects at The Metropolitan Museum of Art, New York, NY, from on or...

  4. 78 FR 11725 - Culturally Significant Objects Imported for Exhibition Determinations: “Claes Oldenburg: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... custodians. I also determine that the exhibition or display of the exhibit objects at the Museum of Modern Art, New York, New York, from on or about April 14, 2013, until on or about August 5, 2013, the Walker Art Center, Minneapolis, Minnesota, from on or about September 14, 2013, until on or about January...

  5. 78 FR 14619 - Culturally Significant Objects Imported for Exhibition Determinations: “Sicily: Art and Invention...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... Greece and Rome'' ACTION: Notice, correction. SUMMARY: On September 5, 2012, notice was published on page... pertaining to the exhibit ``Sicily: Art and Invention Between Greece and Rome.'' The referenced notice is... and Invention Between Greece and Rome,'' imported from abroad for temporary exhibition within...

  6. 76 FR 33398 - Culturally Significant Objects Imported for Exhibition Determinations; “Lyonel Feininger: At the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... World'' Summary: Notice is hereby given of the following determinations: Pursuant to the authority... Authority No. 236-3 of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Lyonel Feininger: At the Edge of the World,'' imported from abroad for temporary exhibition within...

  7. 75 FR 53731 - Culturally Significant Objects Imported for Exhibition Determinations: “Sheila Hicks: 50 Years”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... that the exhibition or display of the exhibit objects at the Addison Gallery of American Art, Phillips... Institute of Contemporary Art, University of Pennsylvania, Philadelphia, PA, from on or about March 25, 2011, until on or about August 7, 2011; at the Mint Museum Craft + Design, Charlotte, NC, from on or...

  8. 77 FR 51606 - Culturally Significant Objects Imported for Exhibition Determinations: “Extravagant Inventions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... Furniture of the Roentgens,'' Formerly Titled ``Seductive Luxury and Innovation: The Furniture of Abraham... State pertaining to the exhibition ``Seductive Luxury and Innovation: The Furniture of Abraham and David Roentgen.'' The referenced notice is corrected here to change the exhibition name to...

  9. 75 FR 23318 - Culturally Significant Objects Imported for Exhibition Determinations: “John Baldessari: Pure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978... October 19, 1999, as amended, and Delegation of Authority No. 257 of April 15, 2003 , I hereby determine... exhibition or display of the exhibit objects at the Los Angeles County Museum of Art, Los Angeles, CA,...

  10. 78 FR 27470 - Culturally Significant Objects Imported for Exhibition Determinations: “Impressionists on the Water”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978... exhibition or display of the exhibit objects at the Fine Arts Museums of San Francisco, San Francisco, CA..., from on or about November 9, 2013, until on or about February 17, 2014, and at possible...

  11. 77 FR 75253 - Culturally Significant Objects Imported for Exhibition Determinations: “Wait, Later This Will Be...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Wait, Later This Will Be Nothing..., 2003), I hereby determine that the objects to be included in the exhibition ``Wait, Later This Will Be..., 2013, and at possible additional exhibitions or venues yet to be determined, is in the...

  12. 76 FR 75939 - Culturally Significant Objects Imported for Exhibition Determinations: “Works of Art Coming to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Works of Art Coming to the U.S. for Exhibition'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority..., 2003), I hereby determine that the objects to be included in the exhibition ``Works of Art Coming...

  13. 77 FR 28419 - Culturally Significant Objects Imported for Exhibition Determinations: “Gauguin, Cézanne, Matisse...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Gauguin, C zanne, Matisse: Visions..., 2003), I hereby determine that the objects to be included in the exhibition ``Gauguin, C zanne, Matisse: Visions of Arcadia,'' imported from abroad for temporary exhibition within the United States, are...

  14. 77 FR 26599 - Culturally Significant Objects Imported for Exhibition Determinations: “The Artist in the Garden”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Artist in the Garden'' SUMMARY... objects to be included in the exhibition ``The Artist in the Garden'' imported from abroad for temporary... exhibit objects at The New York Botanical Garden, Bronx, NY, from on or about May 19, 2012, until on...

  15. 78 FR 24462 - Culturally Significant Objects Imported for Exhibition; Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... Faith in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times... the exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice...

  16. 76 FR 63341 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... in Biblical Times'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...: Life and Faith in Biblical Times'' imported from abroad for temporary exhibition within the...

  17. 78 FR 62354 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-18

    ... in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times'' ACTION... exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice was corrected...

  18. 78 FR 16565 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times'' ACTION... exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice was corrected...

  19. 78 FR 33465 - Culturally Significant Objects Imported for Exhibition Determinations: “Interwoven Globe: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Textile Trade, 1500- 1800'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...: The Worldwide Textile Trade, 1500-1800,'' imported from abroad for temporary exhibition within...

  20. 75 FR 51518 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Masterpieces...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... National Picasso, Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... agreement with the foreign owner or custodian. I also determine that the exhibition or display of...

  1. 78 FR 68134 - Culturally Significant Objects Imported for Exhibition Determinations: “Renaissance to Goya...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ... Drawings from Spain'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... ``Renaissance to Goya: Prints and Drawings from Spain,'' imported from abroad for temporary exhibition...

  2. 77 FR 6621 - Culturally Significant Objects Imported for Exhibition Determinations: “The Rylands Haggadah...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... Jewish Art in Context'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...: Medieval Jewish Art in Context,'' imported from abroad for temporary exhibition within the United...

  3. 76 FR 59767 - Culturally Significant Objects Imported for Exhibition Determinations: “Contested Visions in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... Colonial World'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Spanish Colonial World'' imported from abroad for temporary exhibition within the United States, are...

  4. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Changed the World'' Summary: Notice is hereby given of the following determinations: Pursuant to the... Changed the World,'' imported from abroad for temporary exhibition within the United States, are...

  5. 77 FR 12103 - Culturally Significant Objects Imported for Exhibition Determinations: “Colorful Realm: Japanese...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ...-Flower Paintings by It Jakuch (1716-1800)'' SUMMARY: Notice is hereby given of the following... exhibition ``Colorful Realm: Japanese Bird-and-Flower Paintings by It Jakuch (1716-1800),'' imported...

  6. 77 FR 77178 - Culturally Significant Objects Imported for Exhibition Determinations: “Pre-Raphaelites...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... Design, 1848- 1900'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...: Victorian Art and Design, 1848-1900,'' imported from abroad for temporary exhibition within the...

  7. 76 FR 68256 - Culturally Significant Objects Imported for Exhibition Determinations: “Shapeshifting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... Native American Art'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...: Transformations in Native American Art,'' imported from abroad for temporary exhibition within the United...

  8. 76 FR 35068 - Culturally Significant Objects Imported for Exhibition Determinations; “Monet/Lichtenstein: Rouen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    .../Lichtenstein: Rouen Cathedrals,'' imported from abroad for temporary exhibition within the United States, are... of Fine Arts, Boston, Boston, Massachusetts, from on or about July 3, 2011, until on or...

  9. 75 FR 45195 - Culturally Significant Objects Imported for Exhibition Determinations: “Literary Lives: Portraits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... Gallery and Abbey Theatre, Ireland,'' imported from abroad for temporary exhibition within the United... the McMullen Museum of Art, Boston College, Chestnut Hill, Massachusetts, from on or about September...

  10. 75 FR 82127 - Culturally Significant Objects Imported for Exhibition Determinations: “Guitar Heroes: Legendary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... From Italy to New York'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``Guitar Heroes: Legendary Craftsmen from Italy to New York,'' imported from abroad...

  11. 77 FR 56698 - Culturally Significant Objects Imported for Exhibition Determinations: “Opera Nobile...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Ancient Italy'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority...: Masterpieces from Ancient Italy,'' imported from abroad for temporary exhibition within the United States,...

  12. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “Chaos and Classicism: Art...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ..., Italy, and Germany, 1918-1936'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Chaos and Classicism: Art in France, Italy, and Germany, 1918-1936,'' imported...

  13. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “Hendrick Avercamp (1585...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Little Ice Age'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Little Ice Age,'' imported from abroad for temporary exhibition within the United States, are of...

  14. 78 FR 61871 - Culturally Significant Objects Imported for Exhibition Determinations: “focus: Monika Baer” and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-04

    ... The Art Institute of Chicago and in the exhibition ``Monika Baer'' at the Williams College Museum of..., from on or about October 24, 2013, until on or about January 26, 2014; the Williams College Museum...

  15. 77 FR 54647 - Culturally Significant Objects Imported for Exhibition Determinations: “Sicily: Art and Invention...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Greece and Rome'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Between Greece and Rome,'' imported from abroad for temporary exhibition within the United States, are...

  16. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Chinese Bronzes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... Shouyang Studio: The Katherine and George Fan Collection'' SUMMARY: Notice is hereby given of the following... and George Fan Collection,'' imported from abroad for temporary exhibition within the United...

  17. 77 FR 10599 - Culturally Significant Objects Imported for Exhibition Determinations: “Elegance and Refinement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ...-Life Paintings of Willem van Aelst'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Elegance and Refinement: The Still-Life Paintings of Willem van Aelst,''...

  18. 77 FR 57637 - Culturally Significant Objects Imported for Exhibition Determinations: “The Place of Provenance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-18

    ... Styles in Tibetan Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``The Place of Provenance--Regional Styles in Tibetan Painting,'' imported from...

  19. 75 FR 54691 - Culturally Significant Objects Imported for Exhibition Determinations: “The Vorticists: Rebel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... London and New York, 1914-18'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... the exhibition ``The Vorticists: Rebel Artists in London and New York, 1914-18,'' imported from...

  20. 77 FR 24554 - Culturally Significant Objects Imported for Exhibition; Determinations: “Quay Brothers: On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... Pharmacist's Prescription for Lip-Reading Puppets'' AGENCY: State Department. ACTION: Notice. SUMMARY: Notice... Lip-Reading Puppets'' imported from abroad for temporary exhibition within the United States, are...

  1. 78 FR 60994 - Culturally Significant Objects Imported for Exhibition Determinations: “In Grand Style...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Korean Art During the Joseon Dynasty'' SUMMARY: Notice is hereby given of the following determinations...: Celebrations in Korean Art during the Joseon Dynasty,'' imported from abroad for temporary exhibition...

  2. 77 FR 8943 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt's Self-Portrait”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... about October 4, 2012 until on or about January 6, 2013; the Seattle Art Museum from on or about February 14, 2013 until on or about May 19, 2013; and the Arkansas Art Center from on or about June 6, 2013 until on or about September 9, 2013; and at possible additional exhibitions or venues yet to...

  3. 77 FR 25780 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt, Van Dyck...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... from on or about October 4, 2012 to on or about January 6, 2013; the Seattle Art Museum from on or about February 14, 2013 to on or about May 19, 2013; the Arkansas Art Center from on or about June 6, 2013 to on or about September 8, 2013; and at possible additional exhibitions or venues yet to...

  4. 76 FR 27742 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Masterpieces...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-12

    ... National Picasso, Paris'' Summary: Notice is hereby given of the following determinations: Pursuant to the... ``Picasso: Masterpieces from the Mus e National Picasso, Paris,'' imported from abroad for temporary... loan agreement with the foreign owner or custodian. I also determine that the exhibition or display...

  5. 78 FR 44188 - Culturally Significant Objects Imported for Exhibition Determinations: “Before and After the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ...: Anishinaabe Artists of the Great Lakes'' AGENCY: Department of State. ACTION: Notice, correction. SUMMARY: On...: Anishinaabe Artists of the Great Lakes.'' The referenced notice is corrected here to include additional... exhibition ``Before and after the Horizon: Anishinaabe Artists of the Great Lakes,'' imported from abroad...

  6. 76 FR 1660 - Culturally Significant Objects Imported for Exhibition Determinations: “Reconfiguring an African...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... to the Mask by Modern and Contemporary Artists From Three Continents'' SUMMARY: Notice is hereby... to the Mask by Modern and Contemporary Artists from Three Continents,'' imported from abroad for... display of the exhibit objects at the Metropolitan Museum of Art, New York, NY, from on or about March...

  7. 77 FR 3320 - Culturally Significant Objects Imported for Exhibition Determinations: “Renoir, Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... [Federal Register Volume 77, Number 14 (Monday, January 23, 2012)] [Notices] [Page 3320] [FR Doc... Educational and Cultural Affairs, Department of State. [FR Doc. 2012-1265 Filed 1-20-12; 8:45 am] BILLING CODE... Exhibition Determinations: ``Renoir, Impressionism, and Full-Length Painting'' SUMMARY: Notice is...

  8. 77 FR 32168 - Culturally Significant Object Imported for Exhibition Determinations: “Elegance and Refinement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ...-Life Paintings of Willem van Aelst'' AGENCY: Department of State. ACTION: Notice, correction. SUMMARY... Refinement: The Still-Life Paintings of Willem van Aelst.'' The referenced notice is corrected here to... in the exhibition ``Elegance and Refinement: The Still-Life Paintings of Willem van Aelst,''...

  9. Astronomy's New Messengers: A traveling exhibit to reach out to a young adult audience

    NASA Astrophysics Data System (ADS)

    Cavaglià, Marco; Hendry, Martin; Márka, Szabolcs; Reitze, David H.; Riles, Keith

    2010-05-01

    The Laser Interferometer Gravitational-wave Observatory exhibit Astronomy's New Messengers: Listening to the Universe with Gravitational Waves is traveling to colleges, universities, museums and other public institutions throughout the United States. In 2010, an extended version of this exhibit will appear in a New York City venue that is accessible to a large and diverse cross section of the general public. Astronomy's New Messengers primarily communicates with an adolescent and young adult audience, potentially inspiring them into the field of science. Acknowledging that this audience is traditionally a difficult one to attract, the exhibit publicly announces itself in a charismatic fashion to reach its principal goals of broadening the community of people interested in science and encouraging interest in science among young people.

  10. 76 FR 42158 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt and the Face of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rembrandt and the Face of Jesus... determine that the objects to be included in the exhibition ``Rembrandt and the Face of Jesus,''...

  11. 75 FR 54692 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' ACTION... ''Mir : The Dutch Interiors.'' The reference notice is corrected to accommodate an additional object to... determine that the additional object to be included in the exhibition ``Mir : The Dutch...

  12. 75 FR 80885 - Culturally Significant Objects Imported for Exhibition Determinations: “Rooms With a View: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rooms With a View: The Open Window... the exhibition ``Rooms with a View: The Open Window in the 19th Century,'' imported from abroad...

  13. 77 FR 15839 - Culturally Significant Objects Imported for Exhibition Determinations: “Joan Miró: the Ladder of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Joan Mir : the Ladder of Escape... determine that the objects to be included in the exhibition ``Joan Mir : the Ladder of Escape,''...

  14. 75 FR 19668 - Culturally Significant Objects Imported for Exhibition Determinations: “From Xanadu to Dadu: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``From Xanadu to Dadu: The World of... hereby determine that the objects to be included in the exhibition ``From Xanadu to Dadu: The World...

  15. 75 FR 38589 - Culturally Significant Objects Imported for Exhibition Determinations: “The Origins of Writing in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Origins of Writing in the... hereby determine that the objects to be included in the exhibition ``The Origins of Writing in...

  16. 75 FR 82128 - Culturally Significant Objects Imported for Exhibition Determinations: “Gifts of the Sultan: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gifts of the Sultan: The Arts of... the exhibition ``Gifts of the Sultan: The Arts of Giving at the Islamic Courts'' imported from...

  17. 76 FR 63702 - Culturally Significant Objects Imported for Exhibition Determinations: “Aphrodite and the Gods of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Aphrodite and the Gods of Love... determine that the objects to be included in the exhibition ``Aphrodite and the Gods of Love,''...

  18. 77 FR 64373 - Culturally Significant Object Imported for Exhibition Determinations: “Erotic Gold: The Art and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Erotic Gold: The Art and Life of... April 15, 2003), I hereby determine that the object to be included in the exhibition ``Erotic Gold:...

  19. 77 FR 57637 - Culturally Significant Objects Imported for Exhibition Determinations: “City of Gold: Tomb and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``City of Gold: Tomb and Temple in... ``City of Gold: Tomb and Temple in Ancient Cyprus,'' imported from abroad for temporary exhibition...

  20. 75 FR 57102 - Culturally Significant Objects Imported for Exhibition Determinations: “Titian and the Golden Age...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Titian and the Golden Age of... hereby determine that the objects to be included in the exhibition ``Titian and the Golden Age...

  1. 76 FR 56492 - Culturally Significant Objects Imported for Exhibition Determinations: “Antico: The Golden Age of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Antico: The Golden Age of..., 2003), I hereby determine that the objects to be included in the exhibition ``Antico: The Golden Age...

  2. 76 FR 51458 - Culturally Significant Objects Imported for Exhibition Determinations: “Wonder of the Age: Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Wonder of the Age: Master Painters... Age: Master Painters of India, 1100-1900,'' imported from abroad for temporary exhibition within...

  3. 75 FR 53730 - Culturally Significant Object Imported for Exhibition Determinations: “The Roman Mosaic from Lod...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``The Roman Mosaic from Lod, Israel... of August 28, 2000, I hereby determine that the object to be included in the exhibition ``The...

  4. 76 FR 30751 - Culturally Significant Object Imported for Exhibition Determinations: “Turkish Taste at the Court...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Turkish Taste at the Court of Marie... ``Turkish Taste at the Court of Marie- Antoinette,'' imported from abroad for temporary exhibition...

  5. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition Determination: “Heaven and Earth: Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Culturally Significant Objects Imported for Exhibition Determination: ``Heaven and Earth: Art of Byzantium... determinations made by the Department of State pertaining to the exhibition ``Heaven and Earth: Art of Byzantium... ``Heaven and Earth: Art of Byzantium from Greek Collections,'' at the Art Institute of Chicago,...

  6. 75 FR 13805 - Culturally Significant Objects Imported for Exhibition Determinations: “Race to the End of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Race to the End of the Earth... that the objects to be included in the exhibition ``Race to the End of the Earth,'' imported...

  7. 77 FR 27533 - Culturally Significant Objects Imported for Exhibition Determinations: “Ends of the Earth: Land...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ends of the Earth: Land Art to 1974... determine that the objects to be included in the exhibition ``Ends of the Earth: Land Art to 1974''...

  8. 78 FR 58378 - Culturally Significant Objects Imported for Exhibition Determinations: “Peru: Kingdoms of the Sun...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Peru: Kingdoms of the Sun and the..., 2003), I hereby determine that the objects to be included in the exhibition ``Peru: Kingdoms of the...

  9. 78 FR 4585 - Culturally Significant Objects Imported for Exhibition Determinations: “Albrecht Dürer: Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Albrecht D rer: Master Drawings... Delegation of Authority No. 236-3 of August 28, 2000 (and, as appropriate, Delegation of Authority No. 257 of April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Albrecht D...

  10. 77 FR 31421 - Culturally Significant Objects Imported for Exhibition Determinations: “Portrait of Helena de Kay”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Portrait of Helena de Kay'' SUMMARY... object to be included in the exhibition ``Portrait of Helena de Kay,'' imported from abroad for...

  11. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Rudolf Nureyev: A Life in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rudolf Nureyev: A Life in Dance... determine that the objects to be included in the exhibition ``Rudolf Nureyev: A Life in Dance''...

  12. 78 FR 77771 - Culturally Significant Object Imported for Exhibition Determinations: “Love and Play: A Pair of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Love and Play: A Pair of Paintings by..., I hereby determine that the object to be included in the exhibition ``Love and Play: A Pair...

  13. 76 FR 73759 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Egypt-Art and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ancient Egypt--Art and Magic... included in the exhibition ``Ancient Egypt--Art and Magic: Treasures from the Foundation Gandur pour...

  14. 75 FR 6249 - Culturally Significant Objects Imported for Exhibition Determinations: “Fiery Pool: The Maya and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Fiery Pool: The Maya and the Mythic... hereby determine that the objects to be included in the exhibition ``Fiery Pool: The Maya and the...

  15. 76 FR 65559 - Culturally Significant Objects Imported for Exhibition Determinations: “Mummy: Secrets of the Tomb”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mummy: Secrets of the Tomb'' SUMMARY... objects to be included in the exhibition ``Mummy: Secrets of the Tomb'' imported from abroad for...

  16. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Finding of No Significant Environmental Impact I... Environmental Impact SUBJECT: Finding of No Significant Environmental Impact and Necessary Environmental... human environment. Therefore, the preparation of an environmental impact statement is not necessary....

  17. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Finding of No Significant Environmental Impact I... Environmental Impact SUBJECT: Finding of No Significant Environmental Impact and Necessary Environmental... human environment. Therefore, the preparation of an environmental impact statement is not necessary....

  18. 77 FR 59701 - Culturally Significant Objects Imported for Exhibition Determinations: “Florence at the Dawn of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Florence at the Dawn of Renaissance... at the Dawn of Renaissance: Painting and Illumination,'' imported from abroad for...

  19. 78 FR 38430 - Culturally Significant Objects Imported for Exhibition; Determinations: “Of Heaven and Earth: 500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Of Heaven and Earth: 500 Years of... Earth: 500 Years of Italian Painting from Glasgow Museums,'' imported from abroad for...

  20. Single-, few-, and multilayer graphene not exhibiting significant advantages over graphite microparticles in electroanalysis.

    PubMed

    Goh, Madeline Shuhua; Pumera, Martin

    2010-10-01

    This report compares the electroanalytical performances of single- (G-SL), few- (G-FL), and multilayer graphene (G-ML), graphite microparticles, and edge-plane pyrolytic graphite electrodes in terms of sensitivity, linearity, and repeatability. We show that in the case of differential pulse voltammetric (DPV) detection of ascorbic acid, the sensitivity of a G-SL electrode is about 30% greater than that of G-ML and about 40% greater than graphite microparticles. However, in the case of DPV determination of uric acid, sensitivity is practically the same for all (G-SL, G-FL, and G-ML) and, importantly, the graphite microparticles do provide higher sensitivity than graphenes do for this analyte. Graphenes also do not provide a significant advantage in terms of repeatability. We pose the question of whether the efforts leading to the bulk method of producing single-layer graphene are justified for electroanalytical applications.

  1. DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs.

    PubMed

    Cheng, Liang; Jiang, Yue; Wang, Zhenzhen; Shi, Hongbo; Sun, Jie; Yang, Haixiu; Zhang, Shuo; Hu, Yang; Zhou, Meng

    2016-01-01

    The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the similarity between Disease Ontology (DO) terms and provide the significance of the similarity score. Furthermore, DisSim integrated TCs of diseases from the Comparative Toxicogenomics Database (CTD), which can help to identify potential relationships between TCs and similar diseases. The system can be accessed from http://123.59.132.21:8080/DisSim. PMID:27457921

  2. DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs

    PubMed Central

    Cheng, Liang; Jiang, Yue; Wang, Zhenzhen; Shi, Hongbo; Sun, Jie; Yang, Haixiu; Zhang, Shuo; Hu, Yang; Zhou, Meng

    2016-01-01

    The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the similarity between Disease Ontology (DO) terms and provide the significance of the similarity score. Furthermore, DisSim integrated TCs of diseases from the Comparative Toxicogenomics Database (CTD), which can help to identify potential relationships between TCs and similar diseases. The system can be accessed from http://123.59.132.21:8080/DisSim. PMID:27457921

  3. TTSS2-deficient hha mutant of Salmonella Typhimurium exhibits significant systemic attenuation in immunocompromised hosts

    PubMed Central

    Vishwakarma, Vikalp; Pati, Niladri Bhusan; Ray, Shilpa; Das, Susmita; Suar, Mrutyunjay

    2014-01-01

    Non-typhoidal Salmonella (NTS) infections are emerging as leading problem worldwide and the variations in host immune status append to the concern of NTS. Salmonella enterica serovar Typhimurium is one of the causative agents of NTS infections and has been extensively studied. The inactivation of Salmonella pathogenicity island 2 (SPI2) encoded type-III secretion system 2 (TTSS2) has been reported rendering the strain incapable for systemic dissemination to host sites and has also been proposed as live-attenuated vaccine. However, infections from TTSS2-deficient Salmonella have also been reported. In this study, mutant strain MT15 was developed by inactivation of the hemolysin expression modulating protein (hha) in TTSS2-deficient S. Typhimurium background. The MT15 strain showed significant level of attenuation in immune-deprived murine colitis model when tested in iNos−/−, IL10−/−, and CD40L−/− mice groups in C57BL/6 background. Further, the mutation in hha does not implicate any defect in bacterial colonization to the host gut. The long-term infection of developed mutant strain conferred protective immune responses to suitably immunized streptomycin pre-treated C57BL/6 mice. The immunization enhanced the CD4+ and CD8+ cell types involved in bacterial clearance. The serum IgG and luminal secretory IgA (sIgA) was also found to be elevated after the due course of infection. Additionally, the immunized C57BL/6 mice were protected from the subsequent lethal infection of Salmonella Typhimurium. Collectively, these findings implicate the involvement of hemolysin expression modulating protein (Hha) in establishment of bacterial infection. In light of the observed attenuation of the developed mutant strain, this study proposes the possible significance of SPI2-deficient hha mutant as an alternative live-attenuated vaccine strain for use against lethal Salmonella infections. PMID:24401482

  4. Adult Medication-Free Schizophrenic Patients Exhibit Long-Chain Omega-3 Fatty Acid Deficiency: Implications for Cardiovascular Disease Risk

    PubMed Central

    McNamara, Robert K.; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Dwivedi, Yogesh; Pandey, Ghanshyam N.

    2013-01-01

    Deficiency in long-chain omega-3 (LCn − 3) fatty acids, eicosapentaenoic acid (EPA, 20:5n − 3) and docosahexaenoic acid (DHA, 22:6n − 3), has been implicated in the pathoetiology of cardiovascular disease, a primary cause of excess premature mortality in patients with schizophrenia (SZ). In the present study, we determined erythrocyte EPA + DHA levels in adult medication-free patients SZ (n = 20) and age-matched healthy controls (n = 24). Erythrocyte EPA + DHA composition exhibited by SZ patients (3.5%) was significantly lower than healthy controls (4.5%, −22%, P = 0.007). The majority of SZ patients (72%) exhibited EPA+DHA levels ≤4.0% compared with 37% of controls (Chi-square, P = 0.001). In contrast, the omega-6 fatty acid arachidonic acid (AA, 20:4n − 6) (+9%, P = 0.02) and the AA:EPA + DHA ratio (+28%, P = 0.0004) were significantly greater in SZ patients. Linoleic acid (18:2n − 6) was significantly lower (−12%, P = 0.009) and the erythrocyte 20:3/18:2 ratio (an index of delta6-desaturase activity) was significantly elevated in SZ patients. Compared with same-gender controls, EPA + DHA composition was significantly lower in male (−19%, P = 0.04) but not female (−13%, P = 0.33) SZ patients, whereas the 20:3/18:2 ratio was significantly elevated in both male (+22%, P = 0.008) and female (+22%, P = 0.04) SZ patients. These results suggest that the majority of SZ patients exhibit low LCn − 3 fatty acid levels which may place them at increased risk for cardiovascular morbidity and mortality. PMID:23533712

  5. 76 FR 45646 - Culturally Significant Objects Imported for Exhibition Determinations: “5,000 Years of Chinese...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``5,000 Years of Chinese Jade... Jade Featuring Selections from the National Museum of Taiwan and the Arthur M. Sackler...

  6. 75 FR 82129 - Culturally Significant Objects Imported for Exhibition Determinations: “Francis Alÿs: A Story of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Francis Al s: A Story of Deception'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority vested in me...

  7. 78 FR 61981 - Culturally Significant Objects Imported for Exhibition Determinations: “Ink Art: The Past as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ink Art: The Past as Present in... ``Ink Art: The Past as Present in Contemporary China,'' imported from abroad for temporary...

  8. 69 FR 8512 - Culturally Significant Objects Imported for Exhibition; Determinations: “Coming of Age in Ancient...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2004-02-24

    ....), Delegation of Authority No. 234 of October 1, 1999 (64 FR 56014), Delegation of Authority No. 236 of October 19, 1999 (64 FR 57920), as amended, and Delegation of Authority No. 257 of April 15, 2003 (68 FR... Culturally Significant Objects Imported for Exhibition; Determinations: ``Coming of Age in Ancient...

  9. 76 FR 39974 - Culturally Significant Object Imported for Exhibition Determinations: “Titian's Woman in a Blue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... Bella' '' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... United States, is of cultural significance. The object is imported pursuant to a loan agreement with the... or about January 29, 2012, and at possible additional exhibitions or venues yet to be determined,...

  10. 77 FR 319 - Culturally Significant Objects Imported for Exhibition Determinations: “Put Your Freedom in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Put Your Freedom in the Corner, Save... of Authority No. 257 of April 15, 2003), I hereby determine that the object ``Put Your Freedom in...

  11. The Significance of the Work-Place for Adult Education.

    ERIC Educational Resources Information Center

    Mackie, Karl

    1983-01-01

    Recognition of the importance of the workplace derives from the pervasive influence of work on adult development, the substantial scale of education and training carried out at work, changes in the nature of work and occupations, and new forms and content in worker education. (SK)

  12. Diet selection exhibited by juvenile and adult lifestages of the omnivores Western tarnished plant bug, Lygus hesperus and tarnished plant bug, Lygus lineolaris.

    PubMed

    Hagler, James R; Jackson, C Glen; Blackmer, Jacquelyn L

    2010-01-01

    Lygus hesperus Knight and Lygus lineolaris (Palisot de Beauvois) (Heteroptera: Miridae) are economically important plant bugs on many crops worldwide. However, these omnivores are also facultative predators on a wide variety of insects. This study was conducted to quantify and compare herbivory and carnivory exhibited among different lifestages of these two insect pests. The feeding activity of a total of 422 individuals was observed for 1 h each in feeding arenas containing a cotton leaf disk and copious amounts of the sweetpotato whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) eggs, nymphs and adults. The L. hesperus and L. lineolaris lifestages examined included adults and 3rd, 4th and 5th instar nymphs. Plant feeding occupied the majority of both species' time budget, regardless of the species or lifestage examined. There was a tendency for L. lineolaris lifestages to feed more often and for longer duration on plant tissue than L. hesperus. All lifestages of both species rarely fed on B. tabaci, but when they did, they preferred nymphs > adults > eggs. There were only a few cases where there were significant differences in predation rates and prey handling times exhibited among lifestages and between species, but juvenile L. hesperus tended to be more predaceous than juvenile L. lineolaris on whitefly nymphs and adults and 5th instar and adult L. lineolaris were significantly more herbaceous than their L. hesperus counterparts. In addition, the younger individuals of both species tended to have greater prey handling times than their older counterparts. The significance of these findings is discussed.

  13. Theory of mind through the ages: older and middle-aged adults exhibit more errors than do younger adults on a continuous false belief task.

    PubMed

    Bernstein, Daniel M; Thornton, Wendy Loken; Sommerville, Jessica A

    2011-10-01

    Theory of mind (ToM), or the ability to understand mental states, is a fundamental aspect of social cognition. Previous research has documented marked advances in ToM in preschoolers, and declines in ToM in older-aged adults. In the present study, younger (n=37), middle-aged (n=20), and older (n=37) adults completed a continuous false belief task measuring ToM. Middle-aged and older adults exhibited more false belief bias than did younger adults, irrespective of language ability, executive function, processing speed, and memory. The authors conclude that ToM declines from younger to older adulthood, independent of age-related changes to domain-general cognitive functioning.

  14. 78 FR 16565 - Culturally Significant Objects Imported for Exhibition Determinations: “Le Corbusier: An Atlas of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... Landscapes'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Modern Landscapes,'' imported from abroad for temporary exhibition within the United States, are...

  15. Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2

    PubMed Central

    Zhao, Wensi; Luo, Yi; Li, Boyi; Zhang, Tao

    2016-01-01

    Accumulating evidence supports the existence of cancer stem cells (CSCs) in human tumors, and the successful certification of CSCs may lead to the identification of therapeutic targets, which are more effective for the treatment of cancer. The use of spherical cancer models has increased in popularity in cancer stem cell investigations. Tumorospheres, which are used as a model of CSCs and are established in serum-free medium supplemented with growth factors under non-adherent conditions, are one of the most commonly used cancer spherical models and are a valuable method for enriching the CSC fraction. To investigate whether this model is applicable in lung cancer (LC), the identification of lung CSCs and their capacities is essential. In the present study, lung CSCs were enriched by sphere-forming culturing and their stem-like properties were assessed. The results indicated that the lung tumorospheres had enhanced proliferation, clonality, invasion and cisplatin-resistance, and showed significantly increased expression levels of CD133 and breast cancer resistance protein (ABCG2). These results, together with findings previously reported in literature, indicated that the sphere-forming culturing of LC cells induced the enrichment of CSCs and that the tumorospheres exhibited stem cell characteristics. In addition, the higher expression levels of CD133 and ABCG2 in the tumorospheres may provide a rationale for therapeutic targets for LC. PMID:27432082

  16. Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning.

    PubMed

    Biane, Jeremy S; Takashima, Yoshio; Scanziani, Massimo; Conner, James M; Tuszynski, Mark H

    2016-03-16

    Layer 5 neurons of the neocortex receive direct and relatively strong input from the thalamus. However, the intralaminar distribution of these inputs and their capacity for plasticity in adult animals are largely unknown. In slices of the primary motor cortex (M1), we simultaneously recorded from pairs of corticospinal neurons associated with control of distinct motor outputs: distal forelimb versus proximal forelimb. Activation of ChR2-expressing thalamocortical afferents in M1 before motor learning produced equivalent responses in monosynaptic excitation of neurons controlling the distal and proximal forelimb, suggesting balanced thalamic input at baseline. Following skilled grasp training, however, thalamocortical input shifted to bias activation of corticospinal neurons associated with control of the distal forelimb. This increase was associated with a cell-specific increase in mEPSC amplitude but not presynaptic release probability. These findings demonstrate distinct and highly segregated plasticity of thalamocortical projections during adult learning. PMID:26948893

  17. The fetal/neonatal mouse liver exhibits transcriptional features of the adult pancreas.

    EPA Science Inventory

    Metabolic homeostasis of the organism is maintained by the liver’s ability to detoxify and eliminate xenobiotics through the expression of xenobiotic metabolism enxymes (XME). The fetus and neonate have been hypothesized to exhibit increased sensitivity to xenobiotic toxicity. T...

  18. On the significance of adult play: what does social play tell us about adult horse welfare?

    PubMed

    Hausberger, Martine; Fureix, Carole; Bourjade, Marie; Wessel-Robert, Sabine; Richard-Yris, Marie-Annick

    2012-04-01

    Play remains a mystery and adult play even more so. More typical of young stages in healthy individuals, it occurs rarely at adult stages but then more often in captive/domestic animals, which can imply spatial, social and/or feeding deprivations or restrictions that are challenging to welfare, than in animals living in natural conditions. Here, we tested the hypothesis that adult play may reflect altered welfare states and chronic stress in horses, in which, as in several species, play rarely occurs at adult stages in natural conditions. We observed the behaviour (in particular, social play) of riding school horses during occasional outings in a paddock and measured several stress indicators when these horses were in their individual home boxes. Our results revealed that (1) the number of horses and rates of adult play appeared very high compared to field report data and (2) most stress indicators measured differed between 'players' and 'non-players', revealing that most 'playful' animals were suffering from more chronic stress than 'non-playful' horses. Frequency of play behaviour correlated with a score of chronic stress. This first discovery of a relationship between adult play and altered welfare opens new lines of research that certainly deserves comparative studies in a variety of species.

  19. On the significance of adult play: what does social play tell us about adult horse welfare?

    NASA Astrophysics Data System (ADS)

    Hausberger, Martine; Fureix, Carole; Bourjade, Marie; Wessel-Robert, Sabine; Richard-Yris, Marie-Annick

    2012-04-01

    Play remains a mystery and adult play even more so. More typical of young stages in healthy individuals, it occurs rarely at adult stages but then more often in captive/domestic animals, which can imply spatial, social and/or feeding deprivations or restrictions that are challenging to welfare, than in animals living in natural conditions. Here, we tested the hypothesis that adult play may reflect altered welfare states and chronic stress in horses, in which, as in several species, play rarely occurs at adult stages in natural conditions. We observed the behaviour (in particular, social play) of riding school horses during occasional outings in a paddock and measured several stress indicators when these horses were in their individual home boxes. Our results revealed that (1) the number of horses and rates of adult play appeared very high compared to field report data and (2) most stress indicators measured differed between `players' and `non-players', revealing that most `playful' animals were suffering from more chronic stress than `non-playful' horses. Frequency of play behaviour correlated with a score of chronic stress. This first discovery of a relationship between adult play and altered welfare opens new lines of research that certainly deserves comparative studies in a variety of species.

  20. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “The Pre-Raphaelite Lens...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Photography and Painting, 1848-1875'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``The Pre-Raphaelite Lens: British Photography and Painting, 1848-1875,'' imported...

  1. 75 FR 28095 - Culturally Significant Object Imported for Exhibition Determinations: “E Ku Ana Ka Paia...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ..., Responsibility and the Ku Images'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...: Unification, Responsibility and the Ku Images,'' imported from abroad for temporary exhibition within...

  2. 76 FR 6650 - Culturally Significant Objects Imported for Exhibition Determinations: “Splendors of Faith/Scars...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ...: The Arts of the Missions of Northern New Spain, 1600-1821'' SUMMARY: Notice is hereby given of the... exhibition ``Splendors of Faith/Scars of Conquest: The Arts of the Missions of Northern New Spain,...

  3. 77 FR 43644 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantine Art in the Mary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... Michael Jaharis Galleries of Greek, Roman and Byzantine Art'' SUMMARY: Notice is hereby given of the... exhibition ``Byzantine Art in the Mary and Michael Jaharis Galleries of Greek, Roman and Byzantine...

  4. SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells.

    PubMed

    Biernaskie, Jeffrey; Paris, Maryline; Morozova, Olena; Fagan, B Matthew; Marra, Marco; Pevny, Larysa; Miller, Freda D

    2009-12-01

    Despite the remarkable regenerative capacity of mammalian skin, an adult dermal stem cell has not yet been identified. Here, we investigated whether skin-derived precursors (SKPs) might fulfill such a role. We show that SKPs derive from Sox2(+) hair follicle dermal cells and that these two cell populations are similar with regard to their transcriptome and functional properties. Both clonal SKPs and endogenous Sox2(+) cells induce hair morphogenesis, differentiate into dermal cell types, and home to a hair follicle niche upon transplantation. Moreover, hair follicle-derived SKPs self-renew, maintain their multipotency, and serially reconstitute hair follicles. Finally, grafting experiments show that follicle-associated dermal cells move out of their niche to contribute cells for dermal maintenance and wound-healing. Thus, SKPs derive from Sox2(+) follicle-associated dermal precursors and display functional properties predicted of a dermal stem cell, contributing to dermal maintenance, wound-healing, and hair follicle morphogenesis.

  5. 78 FR 56767 - Culturally Significant Objects Imported for Exhibition Determinations: “Cercle et Carré and the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... Spirit of Abstract Art'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... International Spirit of Abstract Art,'' imported from abroad for temporary exhibition within the United States... Georgia Museum of Art, Athens, Georgia, from on or about October 12, 2013, until on or about January...

  6. 75 FR 27383 - Culturally Significant Objects Imported for Exhibition Determinations: “A Gift From the Desert...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ..., History and Culture of the Arabian Horse'' SUMMARY: Notice is hereby given of the following determinations... Desert: The Art, History and Culture of the Arabian Horse,'' imported from abroad for temporary... exhibit objects at the International Museum of the Horse, from on or about May 29, 2010, until on or...

  7. Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium.

    PubMed

    Marques, Joana; Vilanova, Eduardo; Mourão, Paulo A S; Fernàndez-Busquets, Xavier

    2016-01-01

    The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity. Here, we have explored the antiplasmodial capacity of heparin-like sulfated polysaccharides from the sea cucumbers Ludwigothurea grisea and Isostichopus badionotus, from the red alga Botryocladia occidentalis, and from the marine sponge Desmapsamma anchorata. In vitro experiments demonstrated for most compounds significant inhibition of Plasmodium falciparum growth at low-anticoagulant concentrations. This activity was found to operate through inhibition of erythrocyte invasion by Plasmodium, likely mediated by a coating of the parasite similar to that observed for heparin. In vivo four-day suppressive tests showed that several of the sulfated polysaccharides improved the survival of Plasmodium yoelii-infected mice. In one animal treated with I. badionotus fucan parasitemia was reduced from 10.4% to undetectable levels, and Western blot analysis revealed the presence of antibodies against P. yoelii antigens in its plasma. The retarded invasion mediated by sulfated polysaccharides, and the ensuing prolonged exposure of Plasmodium to the immune system, can be explored for the design of new therapeutic approaches against malaria where heparin-related polysaccharides of low anticoagulating activity could play a dual role as drugs and as potentiators of immune responses. PMID:27071342

  8. Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium

    PubMed Central

    Marques, Joana; Vilanova, Eduardo; Mourão, Paulo A. S.; Fernàndez-Busquets, Xavier

    2016-01-01

    The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity. Here, we have explored the antiplasmodial capacity of heparin-like sulfated polysaccharides from the sea cucumbers Ludwigothurea grisea and Isostichopus badionotus, from the red alga Botryocladia occidentalis, and from the marine sponge Desmapsamma anchorata. In vitro experiments demonstrated for most compounds significant inhibition of Plasmodium falciparum growth at low-anticoagulant concentrations. This activity was found to operate through inhibition of erythrocyte invasion by Plasmodium, likely mediated by a coating of the parasite similar to that observed for heparin. In vivo four-day suppressive tests showed that several of the sulfated polysaccharides improved the survival of Plasmodium yoelii-infected mice. In one animal treated with I. badionotus fucan parasitemia was reduced from 10.4% to undetectable levels, and Western blot analysis revealed the presence of antibodies against P. yoelii antigens in its plasma. The retarded invasion mediated by sulfated polysaccharides, and the ensuing prolonged exposure of Plasmodium to the immune system, can be explored for the design of new therapeutic approaches against malaria where heparin-related polysaccharides of low anticoagulating activity could play a dual role as drugs and as potentiators of immune responses. PMID:27071342

  9. Gas-Phase Ambient Air Contaminants Exhibit Significant Dioxin-like and Estrogen-like Activity in Vitro

    PubMed Central

    Klein, Gail P.; Hodge, Erin M.; Diamond, Miriam L.; Yip, Amelia; Dann, Tom; Stern, Gary; Denison, Michael S.; Harper, Patricia A.

    2006-01-01

    Several adverse health effects, such as respiratory and cardiovascular morbidity, have been linked to exposure to particulate matter in ambient air; however, the biologic activity of gas-phase ambient organic air contaminants has not been examined as thoroughly. Using aryl hydrocarbon receptor (AHR)–based and estrogen receptor (ER)–based cell bioassay systems, we assessed the dioxin-like and estrogenic activities of gas-phase organic ambient air contaminants compared with those of particulate-phase contaminants using samples collected between seasons over 2 years from an urban and a rural location in the Greater Toronto Area, Canada. The concentration of the sum (∑) of polycyclic aromatic hydrocarbons, which was highest in the gas phase, was 10–100 times more abundant than that of ∑polychlorinated biphenyls, ∑nitro-polycyclic aromatic hydrocarbons, and ∑organochlorine pesticides, and 103 to 104 times more abundant than ∑polychlorinated dibenzo-p-dioxins/dibenzofurans. Gas-phase samples induced significant AHR- and ER-dependent gene expression. The activity of the gas-phase samples was greater than that of the particulate-phase samples in the estrogen assay and, in one case, in the AHR assay. We found no strong associations between either summer or winter seasons or urban or rural locations in the relative efficacy of the extracts in either the ER or AHR assay despite differences in chemical composition, concentrations, and abundance. Our results suggest that mechanistic studies of the health effects of ambient air must consider gas and particulate phases because chemicals present in both phases can affect AHR and ER signaling pathways. PMID:16675423

  10. The Developmental Significance of Late Adolescent Substance Use for Early Adult Functioning

    ERIC Educational Resources Information Center

    Englund, Michelle M.; Siebenbruner, Jessica; Oliva, Elizabeth M.; Egeland, Byron; Chung, Chu-Ting; Long, Jeffrey D.

    2013-01-01

    This study examines the predictive significance of late adolescent substance use groups (i.e., abstainers, experimental users, at-risk users, and abusers) for early adult adaptation. Participants (N = 159) were drawn from a prospective longitudinal study of first-born children of low-income mothers. At 17.5 years of age, participants were assigned…

  11. [Mutation and expression of LEF1 in adult acute lymphocytic leukemia and their clinical significance].

    PubMed

    Liu, Juan; Guo, Xing; Ge, Zheng; Zhang, Run; Xu, Jing-Yan; Li, Min; Wu, Yu-Jie; Qiao, Chun; Qiu, Hai-Rong; Zhang, Jian-Fu; Li, Jian-Yong

    2014-10-01

    Lymphoid enhancer factor 1 (LEF1) is a key transcription factor in Wingless-type (Wnt) pathway. The present study was aimed to explore the genetic mutation and expression of LEF1, and their clinical significance in adult patients with acute lymphocytic leukemia (ALL). Genomic DNA was amplified and sequenced to detect the mutation of LEF1 in 131 newly diagnosed adult patients with ALL. Quantitative PCR (qPCR) was performed to detect the expression of LEF1. Moreover, the correlations between mutations and expression of LEF1 with clinical characteristics were analyzed. The results showed that the frequency of LEF1 mutation in adult ALL was 3.1% (4/131) and all of them were point mutations located in exon 2 and 3; the median white blood cell count and median percentage of blasts at diagnosis were significantly higher in LEF1 high expression group than in low expression group (70.6 × 10⁹/L vs 26.2 × 10⁹/L)(P = 0.010); (81.0% vs 57.0%) (P = 0.014); in addition, the percentage of patients with Philadelphia chromosome positive and patients in high-risk group significantly increased in LEF1 high expression group compared with that in low expression group (66.7% vs 36.5%) (P = 0.038); (79.2% vs 56.2%) (P = 0.044). It is concluded that high expression of LEF1 may play an important role on development of adult ALL.

  12. [Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].

    PubMed

    Lu, Hai-Yan; Xia, Hai-Long; Chen, Xiao-Wen; Zhu, Li-Xin; Wang, Qing-Yi; Cheng, Xin

    2011-04-01

    This study was aimed to investigate the expression and clinical significance of CDX1, CDX2 and CDX4 genes in acute lymphocytic leukemia (ALL). Expressions of CDX1, CDX2, and CDX4 in 51 adult acute lymphocytic leukemia patients and 14 healthy subjects were detected by reverse transcription polymerase chain reaction (RT-PCR). The results indicated that CDX1, CDX2 and CDX4 were not expressed in 14 healthy persons and 15 CR ALL patients, the positive expression rate of CDX2 gene in de novo ALL patients was 60.8%, while it obviously decreased in patients with complete remission (CR) (p < 0.05); the expression of CDX2 was increased again in relapsed patients (81.8%). When the expression of CDX2 was analyzed in different risk groups of ALL patients, the CDX2 expression rate in high risk (HR) patients was 91.7%, and that in the standard risk (SR) group was 45.7%. Furthermore, analyses of CDX1 and CDX4 expression in series of ALL samples did not show the expression of these genes. In patients with adult ALL at diagnosis and relapse, the CR rate of patients with CDX2 positive expression was lower than that of patients with CDX2 negative expression (p < 0.05). The median survival time in CDX2 positive expression patients was shorter than that in negative expression patient. It is concluded that expression of CDX2 may correlated with pathogenesis and relapse of adult ALL, but the expression of CDX1 and CDX4 don' t associated with pathogenesis and relapse of adult ALL; the CR rate and prognosis of patients with CDX2 positive expression is lower and poor. The expression of CDX2 may be used as a marker for occurrence, relapse and poor prognosis of adult ALL patients.

  13. Three-dimensional scaffolds of fetal decellularized hearts exhibit enhanced potential to support cardiac cells in comparison to the adult.

    PubMed

    Silva, A C; Rodrigues, S C; Caldeira, J; Nunes, A M; Sampaio-Pinto, V; Resende, T P; Oliveira, M J; Barbosa, M A; Thorsteinsdóttir, S; Nascimento, D S; Pinto-do-Ó, P

    2016-10-01

    A main challenge in cardiac tissue engineering is the limited data on microenvironmental cues that sustain survival, proliferation and functional proficiency of cardiac cells. The aim of our study was to evaluate the potential of fetal (E18) and adult myocardial extracellular matrix (ECM) to support cardiac cells. Acellular three-dimensional (3D) bioscaffolds were obtained by parallel decellularization of fetal- and adult-heart explants thereby ensuring reliable comparison. Acellular scaffolds retained main constituents of the cardiac ECM including distinctive biochemical and structural meshwork features of the native equivalents. In vitro, fetal and adult ECM-matrices supported 3D culture of heart-derived Sca-1(+) progenitors and of neonatal cardiomyocytes, which migrated toward the center of the scaffold and displayed elongated morphology and excellent viability. At the culture end-point, more Sca-1(+) cells and cardiomyocytes were found adhered and inside fetal bioscaffolds, compared to the adult. Higher repopulation yields of Sca-1(+) cells on fetal ECM relied on β1-integrin independent mitogenic signals. Sca-1(+) cells on fetal bioscaffolds showed a gene expression profile that anticipates the synthesis of a permissive microenvironment for cardiomyogenesis. Our findings demonstrate the superior potential of the 3D fetal microenvironment to support and instruct cardiac cells. This knowledge should be integrated in the design of next-generation biomimetic materials for heart repair.

  14. Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities

    PubMed Central

    Zhan, Guanqun; Qu, Xiaolan; Liu, Junjun; Tong, Qingyi; Zhou, Junfei; Sun, Bin; Yao, Guangmin

    2016-01-01

    Zephycandidine A (1), the first naturally occurring imidazo[1,2-f]phenanthridine alkaloid, was isolated from Zephyranthes candida (Amaryllidaceae). The structure of 1 was elucidated by spectroscopic analyses and NMR calculation, and a plausible biogenetic pathway for zephycandidine A (1) was proposed. Zephycandidine A (1) exhibited significant cytotoxicity against five cancer cell lines with IC50 values ranging from 1.98 to 7.03 μM with selectivity indices as high as 10 when compared to the normal Beas-2B cell. Further studies suggested that zephycandidine A (1) induces apoptosis in leukemia cells by the activation of caspase-3, upregulation of Bax, downregulation of Bcl-2, and degradation of PARP expression. In addition, zephycandidine A (1) showed acetylcholinesterase (AChE) inhibitory activity, and the docking studies of zephycandidine A (1) and galanthamine (2) with AChE revealed that interactions with W286 and Y337 are necessary. PMID:27658482

  15. Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities

    NASA Astrophysics Data System (ADS)

    Zhan, Guanqun; Qu, Xiaolan; Liu, Junjun; Tong, Qingyi; Zhou, Junfei; Sun, Bin; Yao, Guangmin

    2016-09-01

    Zephycandidine A (1), the first naturally occurring imidazo[1,2-f]phenanthridine alkaloid, was isolated from Zephyranthes candida (Amaryllidaceae). The structure of 1 was elucidated by spectroscopic analyses and NMR calculation, and a plausible biogenetic pathway for zephycandidine A (1) was proposed. Zephycandidine A (1) exhibited significant cytotoxicity against five cancer cell lines with IC50 values ranging from 1.98 to 7.03 μM with selectivity indices as high as 10 when compared to the normal Beas-2B cell. Further studies suggested that zephycandidine A (1) induces apoptosis in leukemia cells by the activation of caspase-3, upregulation of Bax, downregulation of Bcl-2, and degradation of PARP expression. In addition, zephycandidine A (1) showed acetylcholinesterase (AChE) inhibitory activity, and the docking studies of zephycandidine A (1) and galanthamine (2) with AChE revealed that interactions with W286 and Y337 are necessary.

  16. Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion.

    PubMed

    Khoury, Nathalie; El-Hayek, Stephany; Tarras, Omayr; El-Sabban, Marwan; El-Sibai, Mirvat; Rizk, Sandra

    2014-11-01

    Kefir, a fermented milk product, exhibits anti‑tumoral activity in vivo; yet its mechanism of action remains elusive. Recent studies have focused on the mechanism of action of kefir on cancer cells in vitro. The current study aims at examining the effect of kefir on cell survival, proliferation, and motility of colorectal cancer (CRC) cells. Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. The results show that cell‑free fractions of kefir exhibit an anti‑proliferative effect on Caco‑2 and HT‑29 cells. Analysis of DNA content by flow cytometry revealed the ability of kefir to induce cell cycle arrest at the G1 phase. Kefir was also found to induce apoptosis, as seen by cell death ELISA. Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. Western blotting results revealed an upregulation in Bax:Bcl‑2 ratio, confirming the pro‑apoptotic effect of kefir, and an increase in p53 independent‑p21 expression upon kefir treatment. MMP expression was not altered by kefir treatment. Furthermore, results from time‑lapse motility movies, wound‑healing, and invasion assays showed no effect on the motility of colorectal as well as breast (MCF‑7 and MB‑MDA‑231) cancer cells upon kefir treatment. Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.

  17. Dietary Mannoheptulose Does Not Significantly Alter Daily Energy Expenditure in Adult Labrador Retrievers.

    PubMed

    McKnight, Leslie L; Root-McCaig, Jared; Wright, David; Davenport, Gary M; France, James; Shoveller, Anna Kate

    2015-01-01

    Mannoheptulose (MH), a sugar found in avocados that inhibits glycolysis in vitro, has been preliminarily investigated as a novel food ingredient for dogs. This study aimed to determine the effects of dietary MH, delivered as an extract of un-ripened avocado, on energy expenditure (EE) in healthy adult Labrador Retriever dogs (total of 12 dogs, 26.99 ± 0.634 kg, 4.9 ± 0.2 y). The study was a double-blind, cross-over with each dog receiving both dietary treatments, control (CON) and MH (400 mg/kg of diet; 6 mg/kg BW), in random order. Resting and post-prandial (10 h) EE and respiratory quotient (RQ) were determined by indirect calorimetry (d 42). The following day, body composition was assessed using dual X-ray absorptiometry. Continuous activity monitoring was conducted using an Atical® accelerometer (d 43-47). A vastus lateralis muscle biopsy was obtained prior to the morning meal (d 49) and 4 h after consumption of their meal (d 56) to determine the protein content and phosphorylation of 5' adenosine monophosphate-activated protein kinase (AMPK). Diet did not affect body weight, resting EE or skeletal muscle AMPK phosphorylation. Dogs fed MH had significantly lower post-prandial RQ (p = 0.02) and ratio of fat to lean body mass (p = 0.02). Physical activity during light time periods (but not dark) was lower in dogs fed MH (p < 0.05) during weekends, but not on weekdays. These results suggest that MH affects energy balance of adult dogs, but that these effects are not dose dependent and not due to physical activity. PMID:26656105

  18. Dietary Mannoheptulose Does Not Significantly Alter Daily Energy Expenditure in Adult Labrador Retrievers.

    PubMed

    McKnight, Leslie L; Root-McCaig, Jared; Wright, David; Davenport, Gary M; France, James; Shoveller, Anna Kate

    2015-01-01

    Mannoheptulose (MH), a sugar found in avocados that inhibits glycolysis in vitro, has been preliminarily investigated as a novel food ingredient for dogs. This study aimed to determine the effects of dietary MH, delivered as an extract of un-ripened avocado, on energy expenditure (EE) in healthy adult Labrador Retriever dogs (total of 12 dogs, 26.99 ± 0.634 kg, 4.9 ± 0.2 y). The study was a double-blind, cross-over with each dog receiving both dietary treatments, control (CON) and MH (400 mg/kg of diet; 6 mg/kg BW), in random order. Resting and post-prandial (10 h) EE and respiratory quotient (RQ) were determined by indirect calorimetry (d 42). The following day, body composition was assessed using dual X-ray absorptiometry. Continuous activity monitoring was conducted using an Atical® accelerometer (d 43-47). A vastus lateralis muscle biopsy was obtained prior to the morning meal (d 49) and 4 h after consumption of their meal (d 56) to determine the protein content and phosphorylation of 5' adenosine monophosphate-activated protein kinase (AMPK). Diet did not affect body weight, resting EE or skeletal muscle AMPK phosphorylation. Dogs fed MH had significantly lower post-prandial RQ (p = 0.02) and ratio of fat to lean body mass (p = 0.02). Physical activity during light time periods (but not dark) was lower in dogs fed MH (p < 0.05) during weekends, but not on weekdays. These results suggest that MH affects energy balance of adult dogs, but that these effects are not dose dependent and not due to physical activity.

  19. Dietary Mannoheptulose Does Not Significantly Alter Daily Energy Expenditure in Adult Labrador Retrievers

    PubMed Central

    McKnight, Leslie L.; Root-McCaig, Jared; Wright, David; Davenport, Gary M.; France, James; Shoveller, Anna Kate

    2015-01-01

    Mannoheptulose (MH), a sugar found in avocados that inhibits glycolysis in vitro, has been preliminarily investigated as a novel food ingredient for dogs. This study aimed to determine the effects of dietary MH, delivered as an extract of un-ripened avocado, on energy expenditure (EE) in healthy adult Labrador Retriever dogs (total of 12 dogs, 26.99 ± 0.634 kg, 4.9 ± 0.2 y). The study was a double-blind, cross-over with each dog receiving both dietary treatments, control (CON) and MH (400 mg/kg of diet; 6 mg/kg BW), in random order. Resting and post-prandial (10 h) EE and respiratory quotient (RQ) were determined by indirect calorimetry (d 42). The following day, body composition was assessed using dual X-ray absorptiometry. Continuous activity monitoring was conducted using an Atical® accelerometer (d 43–47). A vastus lateralis muscle biopsy was obtained prior to the morning meal (d 49) and 4 h after consumption of their meal (d 56) to determine the protein content and phosphorylation of 5' adenosine monophosphate-activated protein kinase (AMPK). Diet did not affect body weight, resting EE or skeletal muscle AMPK phosphorylation. Dogs fed MH had significantly lower post-prandial RQ (p = 0.02) and ratio of fat to lean body mass (p = 0.02). Physical activity during light time periods (but not dark) was lower in dogs fed MH (p < 0.05) during weekends, but not on weekdays. These results suggest that MH affects energy balance of adult dogs, but that these effects are not dose dependent and not due to physical activity. PMID:26656105

  20. Women as Learners: The Significance of Gender in Adult Learning. The Jossey-Bass Higher and Adult Education Series.

    ERIC Educational Resources Information Center

    Hayes, Elisabeth; Flannery, Daniele D.

    This book is intended to address the need for information and understanding about adult women's learning and education. It gathers knowledge about women and their learning and places women's learning experiences in the contexts of where women live. The book also promotes an understanding of women's diversity and makes recommendations for future…

  1. High Frequency of Clinically Significant Bacteremia in Adults Hospitalized With Falciparum Malaria.

    PubMed

    Nyein, Phyo Pyae; Aung, Ne Myo; Kyi, Tint Tint; Htet, Zaw Win; Anstey, Nicholas M; Kyi, Mar Mar; Hanson, Josh

    2016-01-01

    Background.  African children with severe falciparum malaria commonly have concomitant Gram-negative bacteremia, but co-infection has been thought to be relatively rare in adult malaria. Methods.  Adults with a diagnosis of falciparum malaria hospitalized at 4 tertiary referral hospitals in Myanmar had blood cultures collected at admission. The frequency of concomitant bacteremia and the clinical characteristics of the patients, with and without bacteremia, were explored. Results.  Of 67 adults hospitalized with falciparum malaria, 9 (13% [95% confidence interval, 5.3%-21.6%]) were also bacteremic on admission, 7 (78%) with Gram-negative enteric organisms (Escherichia coli [n = 3], typhoidal Salmonella species [n = 3], nontyphoidal Salmonella [n = 1]). Bacteremic adults had more severe disease (median Respiratory Coma Acidosis Malaria [RCAM] score 3; interquartile range [IQR], 1-4) than those without bacteremia (median RCAM score 1; IQR, 1-2) and had a higher frequency of acute kidney injury (50% vs 16%, P = .03). Although 35 (52%) were at high risk of death (RCAM score ≥2), all 67 patients in the study survived, 51 (76%) of whom received empirical antibiotics on admission. Conclusions.  Bacteremia was relatively frequent in adults hospitalized with falciparum malaria in Myanmar. Like children in high transmission settings, bacteremic adults in this low transmission setting were sicker than nonbacteremic adults, and were often difficult to identify at presentation. Empirical antibiotics may also be appropriate in adults hospitalized with falciparum malaria in low transmission settings, until bacterial infection is excluded.

  2. Appendicular Fractures: A Significant Problem among Institutionalized Adults with Developmental Disabilities.

    ERIC Educational Resources Information Center

    Ryder, K. M.; Williams, J.; Womack, C.; Nayak, N. G.; Nasef, S.; Bush, A.; Tylavsky, F. A.; Carbone, L.

    2003-01-01

    This study found a high incidence of nontraumatic fractures in adults with developmental disabilities living in a state-run facility, a 7.3% incidence among 391 adults. Factors associated with fractures included use of antiepileptic medication. Although bone mineral density (BMD) by heel ultrasound did not predict fracture, values were much lower…

  3. Expiratory-modulated laryngeal motoneurons exhibit a hyperpolarization preceding depolarization during superior laryngeal nerve stimulation in the in vivo adult rat.

    PubMed

    Bautista, Tara G; Sun, Qi-Jian; Pilowsky, Paul M

    2012-03-22

    Swallowing requires the sequential activation of tongue, pharyngeal and esophageal muscles to propel the food bolus towards the stomach. Aspiration during swallow is prevented by adduction of the vocal cords during the oropharyngeal phase. Expiratory-modulated laryngeal motoneurons (ELM) exhibit a burst of action potentials during swallows elicited by electrical stimulation of the superior laryngeal nerve (SLN). Here we sought to investigate changes in membrane potential in ELM during superior laryngeal nerve stimulation in the anaesthetised, in vivo adult rat preparation. Intracellular recordings of ELM in the caudal nucleus ambiguus (identified by antidromic activation from the recurrent laryngeal nerve) demonstrated that ELM bursting activity following SLN stimulation is associated with a depolarization that is preceded by a small hyperpolarization. During spontaneous ELM bursts, the preceding hyperpolarization separated the bursting activity from its usual post-inspiratory activity. These findings demonstrate that the in vivo adult rat preparation is suitable for the study of swallow-related activity in laryngeal motoneurons. PMID:22326041

  4. Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults

    PubMed Central

    Titlow, Joshua S.; Davis, Ilan; Barker, Amy R.; Dawe, Helen R.

    2016-01-01

    ABSTRACT Cilia are conserved organelles that have important motility, sensory and signalling roles. The transition zone (TZ) at the base of the cilium is crucial for cilia function, and defects in several TZ proteins are associated with human congenital ciliopathies such as nephronophthisis (NPHP) and Meckel–Gruber syndrome (MKS). In several species, MKS and NPHP proteins form separate complexes that cooperate with Cep290 to assemble the TZ, but flies seem to lack core components of the NPHP module. We show that MKS proteins in flies are spatially separated from Cep290 at the TZ, and that flies mutant for individual MKS genes fail to recruit other MKS proteins to the TZ, whereas Cep290 seems to be recruited normally. Although there are abnormalities in microtubule and membrane organisation in developing MKS mutant cilia, these defects are less apparent in adults, where sensory cilia and sperm flagella seem to function quite normally. Thus, localising MKS proteins to the cilium or flagellum is not essential for viability or fertility in flies. PMID:27577095

  5. High Frequency of Clinically Significant Bacteremia in Adults Hospitalized With Falciparum Malaria.

    PubMed

    Nyein, Phyo Pyae; Aung, Ne Myo; Kyi, Tint Tint; Htet, Zaw Win; Anstey, Nicholas M; Kyi, Mar Mar; Hanson, Josh

    2016-01-01

    Background.  African children with severe falciparum malaria commonly have concomitant Gram-negative bacteremia, but co-infection has been thought to be relatively rare in adult malaria. Methods.  Adults with a diagnosis of falciparum malaria hospitalized at 4 tertiary referral hospitals in Myanmar had blood cultures collected at admission. The frequency of concomitant bacteremia and the clinical characteristics of the patients, with and without bacteremia, were explored. Results.  Of 67 adults hospitalized with falciparum malaria, 9 (13% [95% confidence interval, 5.3%-21.6%]) were also bacteremic on admission, 7 (78%) with Gram-negative enteric organisms (Escherichia coli [n = 3], typhoidal Salmonella species [n = 3], nontyphoidal Salmonella [n = 1]). Bacteremic adults had more severe disease (median Respiratory Coma Acidosis Malaria [RCAM] score 3; interquartile range [IQR], 1-4) than those without bacteremia (median RCAM score 1; IQR, 1-2) and had a higher frequency of acute kidney injury (50% vs 16%, P = .03). Although 35 (52%) were at high risk of death (RCAM score ≥2), all 67 patients in the study survived, 51 (76%) of whom received empirical antibiotics on admission. Conclusions.  Bacteremia was relatively frequent in adults hospitalized with falciparum malaria in Myanmar. Like children in high transmission settings, bacteremic adults in this low transmission setting were sicker than nonbacteremic adults, and were often difficult to identify at presentation. Empirical antibiotics may also be appropriate in adults hospitalized with falciparum malaria in low transmission settings, until bacterial infection is excluded. PMID:26989752

  6. High Frequency of Clinically Significant Bacteremia in Adults Hospitalized With Falciparum Malaria

    PubMed Central

    Nyein, Phyo Pyae; Aung, Ne Myo; Kyi, Tint Tint; Htet, Zaw Win; Anstey, Nicholas M.; Kyi, Mar Mar; Hanson, Josh

    2016-01-01

    Background. African children with severe falciparum malaria commonly have concomitant Gram-negative bacteremia, but co-infection has been thought to be relatively rare in adult malaria. Methods. Adults with a diagnosis of falciparum malaria hospitalized at 4 tertiary referral hospitals in Myanmar had blood cultures collected at admission. The frequency of concomitant bacteremia and the clinical characteristics of the patients, with and without bacteremia, were explored. Results. Of 67 adults hospitalized with falciparum malaria, 9 (13% [95% confidence interval, 5.3%–21.6%]) were also bacteremic on admission, 7 (78%) with Gram-negative enteric organisms (Escherichia coli [n = 3], typhoidal Salmonella species [n = 3], nontyphoidal Salmonella [n = 1]). Bacteremic adults had more severe disease (median Respiratory Coma Acidosis Malaria [RCAM] score 3; interquartile range [IQR], 1–4) than those without bacteremia (median RCAM score 1; IQR, 1–2) and had a higher frequency of acute kidney injury (50% vs 16%, P = .03). Although 35 (52%) were at high risk of death (RCAM score ≥2), all 67 patients in the study survived, 51 (76%) of whom received empirical antibiotics on admission. Conclusions. Bacteremia was relatively frequent in adults hospitalized with falciparum malaria in Myanmar. Like children in high transmission settings, bacteremic adults in this low transmission setting were sicker than nonbacteremic adults, and were often difficult to identify at presentation. Empirical antibiotics may also be appropriate in adults hospitalized with falciparum malaria in low transmission settings, until bacterial infection is excluded. PMID:26989752

  7. Children's Drawings of Significant Figures for a Peer or an Adult Audience

    ERIC Educational Resources Information Center

    Burkitt, Esther; Watling, Dawn; Murray, Lucy

    2011-01-01

    The present study assessed if children would present different information in their drawings of emotion eliciting stimuli when they believed that an adult or a child audience would view their drawings. Seventy-five 6-year-olds (44 boys and 31 girls) were allocated to three groups: the reference group, the child audience group and the adult…

  8. Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, impaired adult social behavior and activity patterns

    PubMed Central

    Wise, Alexandra; Tenezaca, Luis; Fernandez, Robert W.; Schatoff, Emma; Flores, Julian; Ueda, Atsushi; Zhong, Xiaotian; Wu, Chun-Fang; Simon, Anne F.; Venkatesh, Tadmiri

    2016-01-01

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder in humans characterized by complex behavioral deficits, including intellectual disability, impaired social interactions and hyperactivity. ASD exhibits a strong genetic component with underlying multi-gene interactions. Candidate gene studies have shown that the neurobeachin gene is disrupted in human patients with idiopathic autism (Castermans et al., 2003). The gene for neurobeachin (NBEA) spans the common fragile site FRA 13A and encodes a signal scaffold protein (Savelyeva et al., 2006). In mice, NBEA has been shown to be involved in the trafficking and function of a specific subset of synaptic vesicles. (Medrihan et al., 2009; Savelyeva, Sagulenko, Schmitt, & Schwab, 2006). rugose (rg) is the Drosophila homologue of the mammalian and human neurobeachin. Our previous genetic and molecular analyses have shown that rg encodes an A kinase anchor protein (DAKAP 550), which interacts with components of the EGFR and Notch mediated signaling pathways, facilitating cross-talk between these and other pathways (Shamloula et al., 2002). We now present functional data from studies on the larval neuromuscular junction that reveal abnormal synaptic architecture and physiology. In addition, adult rg loss-of-function mutants exhibit defective social interactions, impaired habituation, aberrant locomotion and hyperactivity. These results demonstrate that Drosophila neurobeachin (rugose) mutants exhibit phenotypic characteristics reminiscent of human ASD and thus could serve as a genetic model for studying autism spectrum disorders. PMID:26100104

  9. Adult skin-derived precursor Schwann cells exhibit superior myelination and regeneration supportive properties compared to chronically denervated nerve-derived Schwann cells.

    PubMed

    Kumar, Ranjan; Sinha, Sarthak; Hagner, Andrew; Stykel, Morgan; Raharjo, Eko; Singh, Karun K; Midha, Rajiv; Biernaskie, Jeff

    2016-04-01

    Functional outcomes following delayed peripheral nerve repair are poor. Schwann cells (SCs) play key roles in supporting axonal regeneration and remyelination following nerve injury, thus understanding the impact of chronic denervation on SC function is critical toward developing therapies to enhance regeneration. To improve our understanding of SC function following acute versus chronic-denervation, we performed functional assays of SCs from adult rodent sciatic nerve with acute- (Day 5 post) or chronic-denervation (Day 56 post), versus embryonic nerves. We also compared Schwann cells derived from adult skin-derived precursors (aSKP-SCs) as an accessible, autologous alternative to supplement the distal (denervated) nerve. We found that acutely-injured SCs and aSKP-SCs exhibited superior proliferative capacity, promotion of neurite outgrowth and myelination of axons, both in vitro and following transplant into a sciatic nerve crush injury model, while chronically-denervated SCs were severely impaired. Acute injury caused re-activation of transcription factors associated with an immature and pro-myelinating SC state (Oct-6, cJun, Sox2, AP2α, cadherin-19), but was diminished with prolonged denervation in vivo and could not be rescued following expansion in vitro suggesting that this is a permanent deficiency. Interestingly, aSKP-SCs closely resembled acutely injured and embryonic SCs, exhibiting elevated expression of these same transcription factors. In summary, prolonged denervation resulted in SC deficiency in several functional parameters that may contribute to impaired regeneration. In contrast, aSKP-SCs closely resemble the regenerative attributes ascribed to acutely-denervated or embryonic SCs emphasizing their potential as an accessible and autologous source of glia cells to enhance nerve regeneration, particularly following delays to surgical repair.

  10. Disease screening of three breeding populations of adult exhibition budgerigars (Melopsittacus undulatus) in New Zealand reveals a high prevalence of a novel polyomavirus and avian malaria infection.

    PubMed

    Baron, Hamish R; Howe, Laryssa; Varsani, Arvind; Doneley, Robert J T

    2014-03-01

    Disease surveillance is vital to the management of New Zealand's endemic and threatened avian species. Three infectious agents that are potential threats to New Zealand's endemic birds include avian polyomavirus (APV), beak and feather disease virus (BFDV), and avian malaria. All three agents have been reported in New Zealand; however, possible reservoir populations have not been identified. In this communication, we report the first study of APV, BFDV, and avian malaria in introduced adult exhibition budgerigars (Melopsittacus undulatus) in New Zealand. Blood samples were collected from 90 living adult budgerigars from three breeding locations in the North Island of New Zealand. An overall APV prevalence of 22% was determined using a broad-spectrum nested PCR that amplified the major capsid protein VP1 gene of polyomavirus. Phylogenetic analysis of the VP1 gene revealed a unique isolate of APV, which had a sequence divergence of 32% to previously reported budgerigar fledgling disease strains and 33% to the recently reported New Zealand finch isolate. All of the budgerigars sampled were found to be PCR negative for BFDV, and an overall prevalence of 30% was detected by PCR for avian malaria. Sequencing revealed the presence of ubiquitous malarial strains and also the potentially destructive Plasmodium relictum strain. The results of this study suggest that both APV and avian malaria are present in New Zealand adult budgerigars, and our study highlights the need for further studies to determine whether these pathogens in captive bird populations may be a threat or spill over into New Zealand's endemic and threatened avifauna and whether prevention and control methods need to be implemented. PMID:24758122

  11. Concise Review: Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration.

    PubMed

    Rumman, Mohammad; Dhawan, Jyotsna; Kassem, Moustapha

    2015-10-01

    Adult stem cells (ASCs) are tissue resident stem cells responsible for tissue homeostasis and regeneration following injury. In uninjured tissues, ASCs exist in a nonproliferating, reversibly cell cycle-arrested state known as quiescence or G0. A key function of the quiescent state is to preserve stemness in ASCs by preventing precocious differentiation, and thus maintaining a pool of undifferentiated ASCs. Recent evidences suggest that quiescence is an actively maintained state and that excessive or defective quiescence may lead to compromised tissue regeneration or tumorigenesis. The aim of this review is to provide an update regarding the biological mechanisms of ASC quiescence and their role in tissue regeneration.

  12. Does age at onset have clinical significance in older adults with bipolar disorder?

    PubMed Central

    Chu, David; Gildengers, Ariel G.; Houck, Patricia R.; Anderson, Stewart J.; Mulsant, Benoit H.; Reynolds, Charles F.; Kupfer, David J.

    2011-01-01

    Objective While age at onset may be useful in explaining some of the heterogeneity of bipolar disorder (BD) in large, mixed age groups, investigations to date have found few meaningful clinical differences between early versus late age at onset in older adults with BD. Methods Data were collected from sixty-one subjects aged 60 years and older, mean (SD) age 67.6 (7.0), with BD I (75%) and II (25%). Subjects were grouped by early (<40 years; n=43) versus late (≥40 years; n=18) age at onset. Early versus late onset groups were compared on psychiatric comorbidity, medical burden, and percentage of days well during study participation. Results Except for family history of major psychiatric illnesses, there were no differences between the groups on demographic or clinical variables. Patients with early and late onset experienced similar percentages of days well; however, those with early onset had slightly more percentage of days depressed than those with late onset (22% versus 13%) Conclusion Distinguishing older adults with BD by early or late age at onset has limited clinical usefulness. PMID:20082348

  13. Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression.

    PubMed

    Heyward, Frankie D; Walton, R Grace; Carle, Matthew S; Coleman, Mark A; Garvey, W Timothy; Sweatt, J David

    2012-07-01

    Mounting evidence has established that diet-induced obesity (DIO) is associated with deficits in hippocampus-dependent memory. The bulk of research studies dealing with this topic have utilized rats fed a high-fat diet as an experimental model. To date, there has been a paucity of research studies that have established whether the memory deficits exhibited in DIO rats can be recapitulated in mice. Moreover, the majority of experiments that have evaluated memory performance in rodent models of DIO have utilized memory tests that are essentially aversive in nature (i.e., Morris water maze). The current study sought to fill an empirical void by determining if mice maintained on a high-fat diet exhibit deficits in two non-aversive memory paradigms: novel object recognition (NOR) and object location memory (OLM). Here we report that mice fed a high-fat diet over 23 weeks exhibit intact NOR, albeit a marked impairment in hippocampus-dependent OLM. We also determined the existence of corresponding aberrations in gene expression within the hippocampus of DIO mice. DIO mice exhibited significant reductions in both SIRT1 and PP1 mRNA within the hippocampus. Our data suggest that mice maintained on a high-fat diet present with impaired hippocampus-dependent spatial memory and a corresponding alteration in the expression of genes that have been implicated in memory consolidation.

  14. Night eating syndrome in young adults: delineation from other eating disorders and clinical significance.

    PubMed

    Fischer, Sophia; Meyer, Andrea H; Hermann, Ernst; Tuch, Alex; Munsch, Simone

    2012-12-30

    The Night Eating Syndrome (NES) is a recently described disordered eating style whose status in current diagnostic systems needs to be further clarified. The aim of this study was to increase knowledge about the clinical features of NES in a sample of 1514 young adults aged 18-26 years from the general population who participated in an anonymous Internet survey. We first examined characteristics of NES and tried to delineate it from healthy controls as well as from other eating disorders in terms of socio-demography, eating disorder pathology and general psychopathology. Second, we attempted to further clarify the clinical utility of the NES by assessing the degree of distress as well as impairment. Twenty (1.3%) participants with NES were identified and there was only modest overlap between NES and both Binge Eating Disorder (BED) and Bulimia nervosa (BN) according to questionnaire-based DSM-IV criteria. Compared to healthy controls, NES individuals reported more pronounced eating disorder pathology as well as general psychopathology (depressive symptoms, chronic social stress). NES seems to be associated with considerable distress and impairment. Implications for the validity and classification of NES are discussed.

  15. Malignant progressive tumor cell clone exhibits significant up-regulation of cofilin-2 and 27-kDa modified form of cofilin-1 compared to regressive clone.

    PubMed

    Kuramitsu, Yasuhiro; Wang, Yufeng; Okada, Futoshi; Baron, Byron; Tokuda, Kazuhiro; Kitagawa, Takao; Akada, Junko; Nakamura, Kazuyuki

    2013-09-01

    QR-32 is a regressive murine fibrosarcoma cell clone which cannot grow when they are transplanted in mice; QRsP-11 is a progressive malignant tumor cell clone derived from QR-32 which shows strong tumorigenicity. A recent study showed there to be differentially expressed up-regulated and down-regulated proteins in these cells, which were identified by proteomic differential display analyses by using two-dimensional gel electrophoresis and mass spectrometry. Cofilins are small proteins of less than 20 kDa. Their function is the regulation of actin assembly. Cofilin-1 is a small ubiquitous protein, and regulates actin dynamics by means of binding to actin filaments. Cofilin-1 plays roles in cell migration, proliferation and phagocytosis. Cofilin-2 is also a small protein, but it is mainly expressed in skeletal and cardiac muscles. There are many reports showing the positive correlation between the level of cofilin-1 and cancer progression. We have also reported an increased expression of cofilin-1 in pancreatic cancer tissues compared to adjacent paired normal tissues. On the other hand, cofilin-2 was significantly less expressed in pancreatic cancer tissues. Therefore, the present study investigated the comparison of the levels of cofilin-1 and cofilin-2 in regressive QR-32 and progressive QRsP-11cells by western blotting. Cofilin-2 was significantly up-regulated in QRsP-11 compared to QR-32 cells (p<0.001). On the other hand, the difference of the intensities of the bands of cofilin-1 (18 kDa) in QR-32 and QRsP-11 was not significant. However, bands of 27 kDa showed a quite different intensity between QR-32 and QRsP-11, with much higher intensities in QRsP-11 compared to QR-32 (p<0.001). These results suggested that the 27-kDa protein recognized by the antibody against cofilin-1 is a possible biomarker for progressive tumor cells.

  16. Dolutegravir (S/GSK1349572) exhibits significantly slower dissociation than raltegravir and elvitegravir from wild-type and integrase inhibitor-resistant HIV-1 integrase-DNA complexes.

    PubMed

    Hightower, Kendra E; Wang, Ruolan; Deanda, Felix; Johns, Brian A; Weaver, Kurt; Shen, Yingnian; Tomberlin, Ginger H; Carter, H Luke; Broderick, Timothy; Sigethy, Scott; Seki, Takahiro; Kobayashi, Masanori; Underwood, Mark R

    2011-10-01

    The integrase inhibitor (INI) dolutegravir (DTG; S/GSK1349572) has significant activity against HIV-1 isolates with raltegravir (RAL)- and elvitegravir (ELV)-associated resistance mutations. As an initial step in characterizing the different resistance profiles of DTG, RAL, and ELV, we determined the dissociation rates of these INIs with integrase (IN)-DNA complexes containing a broad panel of IN proteins, including IN substitutions corresponding to signature RAL and ELV resistance mutations. DTG dissociates slowly from a wild-type IN-DNA complex at 37°C with an off-rate of 2.7 × 10(-6) s(-1) and a dissociative half-life (t(1/2)) of 71 h, significantly longer than the half-lives for RAL (8.8 h) and ELV (2.7 h). Prolonged binding (t(1/2), at least 5 h) was observed for DTG with IN-DNA complexes containing E92, Y143, Q148, and N155 substitutions. The addition of a second substitution to either Q148 or N155 typically resulted in an increase in the off-rate compared to that with the single substitution. For all of the IN substitutions tested, the off-rate of DTG from IN-DNA complexes was significantly slower (from 5 to 40 times slower) than the off-rate of RAL or ELV. These data are consistent with the potential for DTG to have a higher genetic barrier to resistance, provide evidence that the INI off-rate may be an important component of the mechanism of INI resistance, and suggest that the slow dissociation of DTG may contribute to its distinctive resistance profile.

  17. Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits.

    PubMed

    Byrne, Adam John; Al-Bader, Tamara; Kerrigan, Deirdre; Hickey, Sinead; Laloeuf, Aurelie; Rawlings, Anthony Vincent

    2010-06-01

    Basement membranes are thin structures present in the extracellular matrix that provide a supporting framework on which epithelial and endothelial cells reside. Type IV collagen is present ubiquitously in all basement membranes and plays an important role in cell adhesion, migration differentiation, and growth. These are especially important at the dermoepidermal junction (DEJ) in skin. A reduction in the levels of DEJ proteins occurs in photodamaged skin and especially Type IV collagen at the base of a wrinkle. In these studies, the ability of a triple peptide complex (TPC) to stimulate the production of collagen IV in human skin fibroblasts and its effects on photoaged skin was investigated. Fibroblasts, matured to represent "aged" cells, were stimulated for 72 h with the TPC as well as the three individual peptides constituting the complex, and collagen IV production by the fibroblasts was determined immunochemically. The results show that stimulation with the individual peptides at doses found in 1% (v/v) of the TPC did not result in soluble collagen IV production above levels detected by the non-stimulated cells. However, after stimulation with 1% (v/v) of the TPC, collagen IV was produced by the cells (1.4 ng/ng total protein +/- 0.4 SD, n = 5) when compared to control un-stimulated cells (0.32 ng/ng total protein +/- 0.1 SD, n = 5). This indicates that the combination of the individual peptides is necessary to synergistically stimulate collagen IV production. These findings suggest that the TPC could play a role in the strengthening of the DEJ through its ability to produce collagen IV. In order to determine whether these results translated into significant effects in vivo, we performed two studies. In the first four-week study, a double blind, placebo-controlled and fully randomized clinical study on 22 healthy Caucasian volunteers displaying moderate periorbital wrinkles, a significant reduction in wrinkle parameters determined by profilometry was observed

  18. Adolescents in Institutional Care: Significant Adults, Resilience and Well-Being

    ERIC Educational Resources Information Center

    Mota, Catarina Pinheiro; Matos, Paula Mena

    2015-01-01

    Background: Attachment theory states the importance of secure relationships with significant figures for the development of resilience and well-being. The institutional care context represents a particular environment where relationships beyond the family should be attended for. Objective: The purpose of this study was to analyse the relationship…

  19. Vitamin D, folate, and potential early lifecycle environmental origin of significant adult phenotypes

    PubMed Central

    Lucock, Mark; Yates, Zoë; Martin, Charlotte; Choi, Jeong-Hwa; Boyd, Lyndell; Tang, Sa; Naumovski, Nenad; Furst, John; Roach, Paul; Jablonski, Nina; Chaplin, George; Veysey, Martin

    2014-01-01

    Background and objectives: Vitamin D and folate are highly UV sensitive, and critical for maintaining health throughout the lifecycle. This study examines whether solar irradiance during the first trimester of pregnancy influences vitamin D receptor (VDR) and nuclear folate gene variant occurrence, and whether affected genes influence late-life biochemical/clinical phenotypes. Methodology: 228 subjects were examined for periconceptional exposure to solar irradiance, variation in vitamin D/folate genes (polymerase chain reaction (PCR)), dietary intake (food frequency questionnaire (FFQ)) and important adult biochemical/clinical phenotypes. Results: Periconceptional solar irradiance was associated with VDR-BsmI (P = 0.0008wk7), TaqI (P = 0.0014wk7) and EcoRV (P = 0.0030wk6) variant occurrence between post-conceptional weeks 6–8, a period when ossification begins. Similar effects were detected for other VDR gene polymorphisms. Periconceptional solar irradiance was also associated with 19 bp del-DHFR (P = 0.0025wk6), and to a lesser extent C1420T-SHMT (P = 0.0249wk6), a folate-critical time during embryogenesis. These same genes were associated with several late-life phenotypes: VDR-BsmI, TaqI and ApaI determined the relationship between dietary vitamin D and both insulin (P < 0.0001/BB, 0.0007/tt and 0.0173/AA, respectively) and systolic blood pressure (P = 0.0290/Bb, 0.0299/Tt and 0.0412/AA, respectively), making them important early and late in the lifecycle. While these and other phenotype associations were found for the VDR variants, folate polymorphism associations in later-life were limited to C1420T-SHMT (P = 0.0037 and 0.0297 for fasting blood glucose and HbA1c levels, respectively). We additionally report nutrient–gene relationships with body mass index, thiol/folate metabolome, cognition, depression and hypertension. Furthermore, photoperiod at conception influenced occurrence of VDR-Tru9I and 2R3R-TS genotypes (P = 0.0120 and 0.0360, respectively

  20. Pharmacology of Ultrasonic Vocalizations in adult Rats: Significance, Call Classification and Neural Substrate

    PubMed Central

    Brudzynski, Stefan M.

    2015-01-01

    Pharmacological studies of emotional arousal and initiation of emotional states in rats measured by their ultrasonic vocalizations are reviewed. It is postulated that emission of vocalizations is an inseparable feature of emotional states and it evolved from mother-infant interaction. Positive emotional states are associated with emission of 50 kHz vocalizations that could be induced by rewarding situations and dopaminergic activation of the nucleus accumbens and are mediated by D1, D2, and partially D3 dopamine receptors. Three biologically significant subtypes of 50 kHz vocalizations have been identified, all expressing positive emotional states: (1) flat calls without frequency modulation that serve as contact calls during social interactions; (2) frequencymodulated calls without trills that signal rewarding and significantly motivated situation; and (3) frequency-modulated calls with trills or trills themselves that are emitted in highly emotional situations associated with intensive affective state. Negative emotional states are associated with emission of 22 kHz vocalizations that could be induced by aversive situations, muscarinic cholinergic activation of limbic areas of medial diencephalon and forebrain, and are mediated by M2 muscarinic receptors. Two biologically significant subtypes of 22 kHz vocalizations have been identified, both expressing negative emotional sates: (1) long calls that serve as alarm calls and signal external danger; and (2) short calls that express a state of discomfort without external danger. The positive and negative states with emission of vocalizations are initiated by two ascending reticular activating subsystems: the mesolimbic dopaminergic subsystem as a specific positive arousal system, and the mesolimbic cholinergic subsystem as a specific negative arousal system. PMID:26411761

  1. Pharmacology of Ultrasonic Vocalizations in adult Rats: Significance, Call Classification and Neural Substrate.

    PubMed

    Brudzynski, Stefan M

    2015-01-01

    Pharmacological studies of emotional arousal and initiation of emotional states in rats measured by their ultrasonic vocalizations are reviewed. It is postulated that emission of vocalizations is an inseparable feature of emotional states and it evolved from mother-infant interaction. Positive emotional states are associated with emission of 50 kHz vocalizations that could be induced by rewarding situations and dopaminergic activation of the nucleus accumbens and are mediated by D1, D2, and partially D3 dopamine receptors. Three biologically significant subtypes of 50 kHz vocalizations have been identified, all expressing positive emotional states: (1) flat calls without frequency modulation that serve as contact calls during social interactions; (2) frequencymodulated calls without trills that signal rewarding and significantly motivated situation; and (3) frequency-modulated calls with trills or trills themselves that are emitted in highly emotional situations associated with intensive affective state. Negative emotional states are associated with emission of 22 kHz vocalizations that could be induced by aversive situations, muscarinic cholinergic activation of limbic areas of medial diencephalon and forebrain, and are mediated by M2 muscarinic receptors. Two biologically significant subtypes of 22 kHz vocalizations have been identified, both expressing negative emotional sates: (1) long calls that serve as alarm calls and signal external danger; and (2) short calls that express a state of discomfort without external danger. The positive and negative states with emission of vocalizations are initiated by two ascending reticular activating subsystems: the mesolimbic dopaminergic subsystem as a specific positive arousal system, and the mesolimbic cholinergic subsystem as a specific negative arousal system.

  2. Clinical Significance and Characterization of Streptococcus tigurinus Isolates in an Adult Population.

    PubMed

    Bourassa, Lori; Clarridge, J E

    2015-11-01

    Streptococcus tigurinus is a newly described member of the Streptococcus mitis group. Due to the difficulty in distinguishing viridans group streptococci (VGS) by phenotype, analysis of 16S rRNA sequences is necessary for the accurate identification of most species. Through a laboratory policy of analyzing all clinically significant isolates from the VGS group by16S rRNA gene sequencing, we identified 14 S. tigurinus isolates from 11 patients. The Vitek 2 system most commonly gave an excellent rating to an incorrect identification (e.g., Streptococcus mitis), as did matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) (e.g., Streptococcus oralis). S. tigurinus strains were recovered from numerous body sites, including the blood, peritoneal fluid, bone, synovial fluid, a perianal abscess, and an arm wound. Retrospective chart review indicated that most isolates were clinically significant, with bacteremia (n = 5), soft tissue infections (n = 3) osteomyelitis (n = 2), infected joint prosthesis (n = 2), and peritonitis (n = 2) being the most common, thus expanding the spectrum of disease associated with S. tigurinus.

  3. Significance of metabolite extraction method for evaluating sulfamethazine toxicity in adult zebrafish using metabolomics.

    PubMed

    De Sotto, Ryan; Medriano, Carl; Cho, Yunchul; Seok, Kwang-Seol; Park, Youngja; Kim, Sungpyo

    2016-05-01

    Recently, environmental metabolomics has been introduced as a next generation environmental toxicity method which helps in evaluating toxicity of bioactive compounds to non-target organisms. In general, efficient metabolite extraction from target cells is one of the keys to success to better understand the effects of toxic substances to organisms. In this regard, the aim of this study is (1) to compare two sample extraction methods in terms of abundance and quality of metabolites and (2) investigate how this could lead to difference in data interpretation using pathway analysis. For this purpose, the antibiotic sulfamethazine and zebrafish (Danio rerio) were selected as model toxic substance and target organism, respectively. The zebrafish was exposed to four different sulfamethazine concentrations (0, 10, 30, and 50mg/L) for 72h. Metabolites were extracted using two different methods (Bligh and Dyer and solid-phase extraction). A total of 13,538 and 12,469 features were detected using quadrupole time-of-flight liquid chromatography mass spectrometry (QTOF LC-MS). Of these metabolites, 4278 (Bligh and Dyer) and 332 (solid phase extraction) were found to be significant after false discovery rate adjustment at a significance threshold of 0.01. Metlin and KEGG pathway analysis showed comprehensive information from fish samples extracted using Bligh and Dyer compared to solid phase extraction. This study shows that proper selection of sample extraction method is critically important for interpreting and analyzing the toxicity data of organisms when metabolomics is applied. PMID:26827276

  4. Effects of the short-term learned significance of task-irrelevant sounds on involuntary attention in children and adults.

    PubMed

    Wetzel, Nicole

    2015-10-01

    The present study aimed to test effects of unexpected task-irrelevant environmental sounds, that were short-term learned to be significant, on deviance-related brain activity (event-related potentials; ERPs) and performance in children aged 9-10 years and young adults. Participants performed three conditions. In the first ignore condition an oddball paradigm was presented including two neutral deviant sounds. In the second learning condition significance was attributed to one of the two deviant sounds by defining it as target. In the third condition participants then performed a version of an oddball paradigm, embedded in a narrative, that included the neutral and the now significant but task-irrelevant deviant sound. Results revealed decreased reaction times and hit rates elicited by significant compared to neutral deviant sounds in both age groups whereas P3a, an indicator of orienting of attention and novelty evaluation, was not affected by deviant's learned significance. In contrast, post-deviant processing, reflected by hit rates and ERPs in trials following a significant deviant compared to those following a neutral deviant, was differently modulated in children and adults. Moreover, a clear P3a was observed in the attend condition in both age groups but in the ignore condition in children only. Results indicate that the short-term learned significance of task-irrelevant sounds modulates performance but not orienting and evaluation processes associated with the P3a. Importantly, results demonstrate children's increased susceptibility to task-irrelevant but significant sounds and the ongoing maturation of attention control in the late childhood.

  5. Significant Improvements in the Practice Patterns of Adult Related Donor Care in US Transplantation Centers.

    PubMed

    Anthias, Chloe; Shaw, Bronwen E; Kiefer, Deidre M; Liesveld, Jane L; Yared, Jean; Kamble, Rammurti T; D'Souza, Anita; Hematti, Peiman; Seftel, Matthew D; Norkin, Maxim; DeFilipp, Zachariah; Kasow, Kimberly A; Abidi, Muneer H; Savani, Bipin N; Shah, Nirali N; Anderlini, Paolo; Diaz, Miguel A; Malone, Adriana K; Halter, Joerg P; Lazarus, Hillard M; Logan, Brent R; Switzer, Galen E; Pulsipher, Michael A; Confer, Dennis L; O'Donnell, Paul V

    2016-03-01

    Recent investigations have found a higher incidence of adverse events associated with hematopoietic cell donation in related donors (RDs) who have morbidities that if present in an unrelated donor (UD) would preclude donation. In the UD setting, regulatory standards ensure independent assessment of donors, one of several crucial measures to safeguard donor health and safety. A survey conducted by the Center for International Blood and Marrow Transplant Research (CIBMTR) Donor Health and Safety Working Committee in 2007 reported a potential conflict of interest in >70% of US centers, where physicians had simultaneous responsibility for RDs and their recipients. Consequently, several international organizations have endeavored to improve practice through regulations and consensus recommendations. We hypothesized that the changes in the 2012 Foundation for the Accreditation of Cellular Therapy and the Joint Accreditation Committee-International Society for Cellular Therapy and European Society for Blood and Marrow Transplantation standards resulting from the CIBMTR study would have significantly impacted practice. Accordingly, we conducted a follow-up survey of US transplantation centers to assess practice changes since 2007, and to investigate additional areas where RD care was predicted to differ from UD care. A total of 73 centers (53%), performing 79% of RD transplantations in the United States, responded. Significant improvements were observed since the earlier survey; 62% centers now ensure separation of RD and recipient care (P < .0001). This study identifies several areas where RD management does not meet international donor care standards, however. Particular concerns include counseling and assessment of donors before HLA typing, with 61% centers first disclosing donor HLA results to an individual other than the donor, the use of unlicensed mobilization agents, and the absence of long-term donor follow-up. Recommendations for improvement are made.

  6. The significance of childhood competence and problems for adult success in work: a developmental cascade analysis.

    PubMed

    Masten, Ann S; Desjardins, Christopher David; McCormick, Christopher M; Kuo, Sally I-Chun; Long, Jeffrey D

    2010-08-01

    Success in the domain of work is a salient developmental task of adulthood and a key indicator of adaptive function in the evaluation of health and psychopathology. Yet few studies have examined pathways to work competence, especially with strategies testing for cumulative cascade effects over time. Cascade models spanning 20 years were tested via structural equation modeling, linking work competence in early adulthood to antecedent competence in work and other domains of competence in childhood and emerging adulthood. Data were drawn from the Project Competence longitudinal study of 205 school children followed for 20 years. Relative fit of alternative models was evaluated by the Bayesian information criterion. As hypothesized, the effectiveness of adaptive behavior in earlier age-salient developmental task domains forecasted later work competence, which also showed strong concurrent links to competence in other domains. Results suggest there are numerous pathways by which success or failure in major developmental task domains in childhood and adolescence may influence adaptation in other domains and eventually work competence, both concurrently and cumulatively over time. Cascade effects highlight the potential significance for later work competence of childhood conduct (antisocial vs. rule-abiding behavior) and social competence with peers, in addition to the ongoing role that academic attainment may have for work success. Work competence also showed considerable stability over a 10-year period during early adulthood. Implications and applications for future research and intervention are discussed.

  7. Outdoor Exhibits

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The National Data Buoy Center (NDBC) at the John C. Stennis Space Center has exhibits located in front of the Visitors Center. These boat-shaped buoys are moored in areas of the ocean that experience hostile environmental conditions. The instruments installed gather information and relay it to the National Weather Service by satellite. Nomad buoys are 20 feet long and weigh 13,900 pounds. They provide information on wind speed and direction, humidity levels, air and sea surface temperature and air pressure. U.S. Coast Guard ships transport buoys to their mooring sites.

  8. Adult acclimation to combined temperature and pH stressors significantly enhances reproductive outcomes compared to short-term exposures.

    PubMed

    Suckling, Coleen C; Clark, Melody S; Richard, Joelle; Morley, Simon A; Thorne, Michael A S; Harper, Elizabeth M; Peck, Lloyd S

    2015-05-01

    This study examined the effects of long-term culture under altered conditions on the Antarctic sea urchin, Sterechinus neumayeri. Sterechinus neumayeri was cultured under the combined environmental stressors of lowered pH (-0.3 and -0.5 pH units) and increased temperature (+2 °C) for 2 years. This time-scale covered two full reproductive cycles in this species and analyses included studies on both adult metabolism and larval development. Adults took at least 6-8 months to acclimate to the altered conditions, but beyond this, there was no detectable effect of temperature or pH. Animals were spawned after 6 and 17 months exposure to altered conditions, with markedly different outcomes. At 6 months, the percentage hatching and larval survival rates were greatest in the animals kept at 0 °C under current pH conditions, whilst those under lowered pH and +2 °C performed significantly less well. After 17 months, performance was not significantly different across treatments, including controls. However, under the altered conditions urchins produced larger eggs compared with control animals. These data show that under long-term culture adult S. neumayeri appear to acclimate their metabolic and reproductive physiology to the combined stressors of altered pH and increased temperature, with relatively little measureable effect. They also emphasize the importance of long-term studies in evaluating effects of altered pH, particularly in slow developing marine species with long gonad maturation times, as the effects of altered conditions cannot be accurately evaluated unless gonads have fully matured under the new conditions. PMID:25491898

  9. Adult acclimation to combined temperature and pH stressors significantly enhances reproductive outcomes compared to short-term exposures.

    PubMed

    Suckling, Coleen C; Clark, Melody S; Richard, Joelle; Morley, Simon A; Thorne, Michael A S; Harper, Elizabeth M; Peck, Lloyd S

    2015-05-01

    This study examined the effects of long-term culture under altered conditions on the Antarctic sea urchin, Sterechinus neumayeri. Sterechinus neumayeri was cultured under the combined environmental stressors of lowered pH (-0.3 and -0.5 pH units) and increased temperature (+2 °C) for 2 years. This time-scale covered two full reproductive cycles in this species and analyses included studies on both adult metabolism and larval development. Adults took at least 6-8 months to acclimate to the altered conditions, but beyond this, there was no detectable effect of temperature or pH. Animals were spawned after 6 and 17 months exposure to altered conditions, with markedly different outcomes. At 6 months, the percentage hatching and larval survival rates were greatest in the animals kept at 0 °C under current pH conditions, whilst those under lowered pH and +2 °C performed significantly less well. After 17 months, performance was not significantly different across treatments, including controls. However, under the altered conditions urchins produced larger eggs compared with control animals. These data show that under long-term culture adult S. neumayeri appear to acclimate their metabolic and reproductive physiology to the combined stressors of altered pH and increased temperature, with relatively little measureable effect. They also emphasize the importance of long-term studies in evaluating effects of altered pH, particularly in slow developing marine species with long gonad maturation times, as the effects of altered conditions cannot be accurately evaluated unless gonads have fully matured under the new conditions.

  10. Serum Vitamin D Is Significantly Inversely Associated with Disease Severity in Caucasian Adults with Obstructive Sleep Apnea Syndrome

    PubMed Central

    Kerley, Conor P.; Hutchinson, Katrina; Bolger, Kenneth; McGowan, Aisling; Faul, John; Cormican, Liam

    2016-01-01

    Study Objectives: To evaluate vitamin D (25(OH)D) levels in obstructive sleep apnea syndrome (OSAS) and possible relationships to OSAS severity, sleepiness, lung function, nocturnal heart rate (HR), and body composition. We also aimed to compare the 25(OH)D status of a subset of OSAS patients compared to controls matched for important determinants of both OSAS and vitamin D deficiency (VDD). Methods: This was a cross-sectional study conducted at an urban, clinical sleep medicine outpatient center. We recruited newly diagnosed, Caucasian adults who had recently undergone nocturnal polysomnography. We compared body mass index (BMI), body composition (bioelectrical impedance analysis), neck circumference, sleepiness (Epworth Sleepiness Scale), lung function, and vitamin D status (serum 25-hydrpoxyvitamin D (25(OH)D) across OSAS severity categories and non-OSAS subjects. Next, using a case-control design, we compared measures of serum 25(OH)D from OSAS cases to non-OSAS controls who were matched for age, gender, skin pigmentation, sleepiness, season, and BMI. Results: 106 adults (77 male; median age = 54.5; median BMI = 34.3 kg/m2) resident in Dublin, Ireland (latitude 53°N) were recruited and categorized as non-OSAS or mild/moderate/severe OSAS. 98% of OSAS cases had insufficient 25(OH)D (< 75 nmol/L), including 72% with VDD (< 50 nmol/L). 25(OH)D levels decreased with OSAS severity (P = 0.003). 25(OH)D was inversely correlated with BMI, percent body fat, AHI, and nocturnal HR. Subsequent multivariate regression analysis revealed that 25(OH)D was independently associated with both AHI (P = 0.016) and nocturnal HR (P = 0.0419). Our separate case-control study revealed that 25(OH)D was significantly lower in OSAS cases than matched, non-OSAS subjects (P = 0.001). Conclusions: We observed widespread vitamin D deficiency and insufficiency in a Caucasian, OSAS population. There were significant, independent, inverse relationships between 25(OH)D and AHI as well as

  11. Fever of unknown origin caused by adult juvenile rheumatoid arthritis: the diagnostic significance of double quotidian fevers and elevated serum ferritin levels.

    PubMed

    Cunha, Burke A

    2004-01-01

    Fever of unknown origin (FUO) in adults is a commonly encountered clinical problem. Treatable causes of FUO in the adult should be the primary focus of the diagnostic workup. Neoplasms have replaced infectious diseases as being the most common cause of FUO in adults, and collagen vascular diseases are now relatively rare. The most important collagen vascular diseases presenting as an FUO include Takayasu's arteritis, Kikuchi's disease, polymyalgia rheumatica, and adult juvenile rheumatoid arthritis (JRA) (adult Still's disease). There are no specific diagnostic tests for these disorders, which commonly present as prolonged fevers that are not easily diagnosed (i.e., FUO). Adult JRA is a rare but important cause of FUO in adults. Typically, patients with adult Still's disease present with liver/spleen involvement, posi-articular arthritis, ocular involvement, and evanescent salmon-colored truncal rash. An important diagnostic finding in adult JRA is the presence of a double quotidian fever, which occurs in few other disorders. Only visceral leishmaniasis and adult JRA are causes of FUO in adults associated with double quotidian fevers. Highly elevated serum ferritin levels are the most important nonspecific diagnostic finding associated with adult JRA. We present a case of FUO caused by adult JRA presenting with diffuse polyarticular migrating arthritis, evanescent rash, and splenomegaly. The diagnosis of adult JRA was suggested by these findings in association with a double quotidian fever and a highly elevated serum ferritin level. Clinicians should appreciate the diagnostic significance of fever patterns and the diagnostic significance of elevated serum ferritin levels in patients with FUO.

  12. Adults with dyslexia exhibit large effects of crowding, increased dependence on cues, and detrimental effects of distractors in visual search tasks.

    PubMed

    Moores, Elisabeth; Cassim, Rizan; Talcott, Joel B

    2011-12-01

    Difficulties in visual attention are increasingly being linked to dyslexia. To date, the majority of studies have inferred functionality of attention from response times to stimuli presented for an indefinite duration. However, in paradigms that use reaction times to investigate the ability to orient attention, a delayed reaction time could also indicate difficulties in signal enhancement or noise exclusion once oriented. Thus, in order to investigate attention modulation and visual crowding effects in dyslexia, this study measured stimulus discrimination accuracy to rapidly presented displays. Adults with dyslexia (AwD) and controls discriminated the orientation of a target in an array of different numbers of - and differently spaced - vertically orientated distractors. Results showed that AwD: were disproportionately impacted by (i) close spacing and (ii) increased numbers of stimuli, (iii) did use pre-cues to modulate attention, but (iv) used cues less successfully to counter effects of increasing numbers of distractors. A greater dependence on pre-cues, larger effects of crowding and the impact of increased numbers of distractors all correlated significantly with measures of literacy. These findings extend previous studies of visual crowding of letters in dyslexia to non-complex stimuli. Overall, AwD do not use cues less, but they do use cues less successfully. We conclude that visual attention is an important factor to consider in the aetiology of dyslexia. The results challenge existing theoretical accounts of visual attention deficits, which alone are unable to comprehensively explain the pattern of findings demonstrated here.

  13. No significant brain volume decreases or increases in adults with high-functioning autism spectrum disorder and above average intelligence: a voxel-based morphometric study.

    PubMed

    Riedel, Andreas; Maier, Simon; Ulbrich, Melanie; Biscaldi, Monica; Ebert, Dieter; Fangmeier, Thomas; Perlov, Evgeniy; Tebartz van Elst, Ludger

    2014-08-30

    Autism spectrum disorder (ASD) is increasingly being recognized as an important issue in adult psychiatry and psychotherapy. High intelligence indicates overall good brain functioning and might thus present a particularly good opportunity to study possible cerebral correlates of core autistic features in terms of impaired social cognition, communication skills, the need for routines, and circumscribed interests. Anatomical MRI data sets for 30 highly intelligent patients with high-functioning autism and 30 pairwise-matched control subjects were acquired and analyzed with voxel-based morphometry. The gray matter volume of the pairwise-matched patients and the controls did not differ significantly. When correcting for total brain volume influences, the patients with ASD exhibited smaller left superior frontal volumes on a trend level. Heterogeneous volumetric findings in earlier studies might partly be explained by study samples biased by a high inclusion rate of secondary forms of ASD, which often go along with neuronal abnormalities. Including only patients with high IQ scores might have decreased the influence of secondary forms of ASD and might explain the absence of significant volumetric differences between the patients and the controls in this study. PMID:24953998

  14. Face-to-Face Sharing with Strangers and Altruistic Punishment of Acquaintances for Strangers: Young Adolescents Exhibit Greater Altruism than Adults

    PubMed Central

    Hao, Jian; Yang, Yue; Wang, Zhiwen

    2016-01-01

    Young adolescents are generally considered to be self-absorbed. Studies indicate that they lack relevant general cognitive abilities, such as impulse control, that mature in early adulthood. However, their idealism may cause them to be more intolerant of unfair treatment to others and thus result in their engaging in more altruistic behavior. The present study aimed to clarify whether young adolescents are more altruistic than adults and thus indicate whether altruistic competence is domain-specific. One hundred 22 young adolescents and adults participated in a face-to-face, two-round, third-party punishment experiment. In each interaction group, a participant served as an allocator who could share money units with a stranger; another participant who knew the allocator could punish the acquaintance for the stranger. Participants reported their emotions after the first round, and at the end of the experiment, the participants justified their behavior in each round. The results indicated that the young adolescents both shared more and punished more than did the adults. Sharing was associated with a reference to fairness in the justifications, but altruistic punishment was associated with subsequent positive emotion. In sum, greater altruism in young adolescents compared to adults with mature cognitive abilities provides evidence of domain-specificity of altruistic competence. Moreover, sharing and altruistic punishment are related to specific cognitive and emotional mechanisms, respectively. PMID:27752246

  15. Impaired Autophagy in Adult Bone Marrow CD34+ Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance.

    PubMed

    Huang, Jinbo; Ge, Meili; Lu, Shihong; Shi, Jun; Yu, Wei; Li, Xingxin; Wang, Min; Zhang, Jizhou; Feng, Sizhou; Dong, Shuxu; Cheng, Xuelian; Zheng, Yizhou

    2016-01-01

    Aplastic anemia (AA) is a bone marrow failure syndrome that is caused largely by profound quantitative and qualitative defects of hematopoietic stem and progenitor cells. However, the mechanisms underlying these defects remain unclear. Under conditions of stress, autophagy acts as a protective mechanism for cells. We therefore postulated that autophagy in CD34+ hematopoietic progenitor cells (HPCs) from AA patients might be impaired and play a role in the pathogenesis of AA. To test this hypothesis, we tested autophagy in CD34+ cells from AA samples and healthy controls and investigated the effect of autophagy on the survival of adult human bone marrow CD34+ cells. We found that the level of autophagy in CD34+ cells from AA patients was significantly lower than in age/sex-matched healthy controls, and lower in cases of severe AA than in those with non-severe AA. Autophagy in CD34+ cells improved upon amelioration of AA but, compared to healthy controls, was still significantly reduced even in AA patients who had achieved a complete, long-term response. We also showed that although the basal autophagy in CD34+ cells was low, the autophagic response of CD34+ cells to "adversity" was rapid. Finally, impaired autophagy resulted in reduced differentiation and proliferation of CD34+ cells and sensitized them to death and apoptosis. Thus, our results confirm that autophagy in CD34+ cells from AA patients is impaired, that autophagy is required for the survival of CD34+ cells, and that impaired autophagy in CD34+ HPCs may play an important role in the pathogenesis of AA. PMID:26930650

  16. Indirect ultrasound measurement of humeral torsion in adolescent baseball players and non-athletic adults: reliability and significance.

    PubMed

    Whiteley, Rod; Ginn, Karen; Nicholson, Leslie; Adams, Roger

    2006-08-01

    Accurate clinical interpretation of shoulder rotation range requires knowledge of the contribution of humeral torsion. This study compares the reliability of indirectly measuring humeral torsion using ultrasound visualisation with direct palpation and compares the degree of humeral torsion in a non-throwing adult population with a population of elite adolescent baseballers. The reliability of a novel method of indirectly measuring humeral torsion using palpation and ultrasound was established prior to using the ultrasound method to determine the amount of humeral torsion in both humeri of a group of 16 non-throwing subjects and 36 elite adolescent baseball players. Excellent inter-tester reliability was found for the ultrasound method of measuring humeral torsion in each arm (ICC 2,1: 0.98 and 0.94) but poor reliability for the direct palpation method (ICC 2,1: 0.51 and 0.49). Using the ultrasound method, side-to-side differences in humeral torsion ranged from 0 to 13 degrees for the non-throwing group and 0 to 29 degrees for the baseball players. This side-to-side difference was significant in the baseball players (p<0.001) but not significant in the non-throwing group (p=0.43). Whilst side-to-side differences in humeral torsion were noted between all subjects irrespective of arm dominance, only throwers demonstrated consistently greater humeral retrotorsion in their throwing arm. A reliable clinical tool for estimating humeral torsion, such as that employed in this study, will allow for a more valid prescription of interventions for the treatment of shoulder dysfunction.

  17. Does head posture have a significant effect on the hyoid bone position and sternocleidomastoid electromyographic activity in young adults?

    PubMed

    Valenzuela, Saúl; Miralles, Rodolfo; Ravera, María José; Zúñiga, Claudia; Santander, Hugo; Ferrer, Marcelo; Nakouzi, Jorge

    2005-07-01

    The aim of this study was to evaluate the associations between head posture (head extension, normal head posture, and head flexion) and anteroposterior head position, hyoid bone position, and the sternocleidomastoid integrated electromyographic (IEMG) activity in a sample of young adults. The study included 50 individuals with natural dentition and bilateral molar support. A lateral craniocervical radiograph was taken for each subject and a cephalometric analysis was performed. Head posture was measured by means of the craniovertebral angle formed by the MacGregor plane and the odontoid plane. According to the value of this angle, the sample was divided into the following three groups: head extension (less than 95 degrees); normal head posture (between 95 degrees and 106 degrees); and head flexion (more than 106 degrees). The following cephalometric measurements were taken to compare the three groups: anteroposterior head position (true vertical plane/pterygoid distance), anteroposterior hyoid bone position (true vertical plane-Ha distance), vertical hyoid bone position (H-H' distance in the hyoid triangle), and CO-C2 distance. In the three groups, IEMG recordings at rest and during swallowing of saliva and maximal voluntary clenching were performed by placing bipolar surface electrodes on the right and left sternocleidomastoid muscles. In addition, the condition with/without craniomandibular dysfunction (CMD) in each group was also assessed. Head posture showed no significant association with anteroposterior head position, anteroposterior hyoid bone position, vertical hyoid bone position, or sternocleidomastoid IEMG activity. There was no association to head posture with/without the condition of CMD. Clinical relevance of the results is discussed.

  18. Circulating kisspeptin levels exhibit sexual dimorphism in adults, are increased in obese prepubertal girls and do not suffer modifications in girls with idiopathic central precocious puberty.

    PubMed

    Pita, Jimena; Barrios, Vicente; Gavela-Pérez, Teresa; Martos-Moreno, Gabriel Á; Muñoz-Calvo, María T; Pozo, Jesús; Rovira, Adela; Argente, Jesús; Soriano-Guillén, Leandro

    2011-09-01

    The system KISS1-KISS1R is one of the main regulators of the hypothalamic-pituitary-gonadal axis and constitutes a link between metabolism and reproduction through its interaction with leptin. The aim of this study was to clarify the possible utility of kisspeptin as a pubertal marker and/or the possible influence of nutritional status in kisspeptin levels. To this end, we have studied kisspeptin plasma levels throughout sexual development and in prepubertal obese girls and girls affected by idiopathic central precocious puberty (CPP). Plasma kisspeptin concentrations were analyzed by RIA. An increase in kisspeptin levels was observed in adult females compared to healthy prepubertal and pubertal girls (p<0.001) and to adult males (p<0.001). Additionally, kisspeptin was increased in prepubertal obese girls compared to healthy prepubertal girls (p<0.01) and girls with idiopathic CPP (p<0.05). As revealed by the regression analysis, in prepubertal healthy and obese girls and girls with idiopathic CCP, the parameters that influenced kisspeptin levels were BMI (R(2)=0.10, p<0.05) and leptin levels (R(2)=0.14, p<0.01). In conclusion, kisspeptin levels do not seem to be a good pubertal marker. The results obtained in prepubertal and idiopathic CCP girls point to a relationship between leptin, BMI and kisspeptin at least in this group, and suggest a possible role for adipose tissue in the modulation kisspeptin synthesis.

  19. Associations between hurtful weight-related comments by family and significant other and the development of disordered eating behaviors in young adults

    PubMed Central

    Eisenberg, Marla E.; Berge, Jerica M.; Fulkerson, Jayne A.; Neumark-Sztainer, Dianne

    2012-01-01

    Background Research has found that weight-teasing is associated with disordered eating in adolescents. This study expands on the existing research by examining associations between hurtful weight comments by family and a significant other and disordered eating in young adults. Methods Data come from 1,902 young adults (mean age 25) who completed surveys in 1998, 2003 and 2009. Correlations were examined between receiving hurtful comments from family and significant others, and four disordered eating behaviors in young adulthood, adjusting for prior disordered eating and prior teasing. Results Disordered eating behaviors were common in young adulthood, and were associated with hearing hurtful weight-related comments from family members and a significant other, for both females and males. Conclusion Disordered eating prevention activities, which include messages about the potential harm associated with hurtful weight-related comments, should be expanded to address young adults, and programs may want to target relationship partners. PMID:21898148

  20. Adult Trade Apprentices: Exploring the Significance of Recognition of Prior Learning and Skill Sets for Earlier Completion. Research Report

    ERIC Educational Resources Information Center

    Hargreaves, Jo; Blomberg, Davinia

    2015-01-01

    The nature of apprenticeships is changing. Increasing proportions of adult apprentices are prompting demand for various alternative pathways to completion. One option for an alternative pathway to accelerate completion is the use of recognition of prior learning (RPL) to identify existing skills and knowledge in combination with gap training. This…

  1. Effects of Multimedia Social Stories on Knowledge of Adult Outcomes and Opportunities among Transition-Aged Youth with Significant Cognitive Disabilities

    ERIC Educational Resources Information Center

    Richter, Sharon; Test, David

    2011-01-01

    Students with significant cognitive disabilities typically experience poor post-school outcomes as adults. Federal legislation and recent research reflect the importance of teaching self-determination skills as a strategy to improve post-school outcomes. However, the National Longitudinal Transition Study-2 (NLTS-2) reported that individuals with…

  2. Varying protein source and quantity does not significantly improve weight loss, fat loss, or satiety in reduced energy diets among midlife adults

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This pilot study tested whether varying protein source and quantity in a reduced energy diet would result in significant differences in weight, body composition, and renin angiotensin aldosterone system activity in midlife adults. Eighteen subjects enrolled in a 5 month weight reduction study, invol...

  3. Vitamin and mineral supplements have a nutritionally significant impact on micronutrient intakes of older adults attending senior centers.

    PubMed

    Weeden, Allisha; Remig, Valentina; Holcomb, Carol Ann; Herald, Thomas J; Baybutt, Richard C

    2010-04-01

    Older adults frequently report use of vitamin and mineral (VM) supplements, although the impact of supplements on dietary adequacy remains largely unknown. The purpose of the current study was to evaluate micronutrient intakes of older adults with emphasis on identifying nutrients most improved by VM supplements, nutrients most likely to remain inadequate, and nutrients most likely consumed in excess. Community-based volunteers were recruited from senior centers and completed a questionnaire querying demographic data, current health status, and VM supplement use. Participants (n = 263) were then contacted by telephone to complete two 24-hour diet recalls and confirm VM supplement use. Dietary adequacy was determined by comparing the ratio of mean dietary intake to the Dietary Reference Intakes (DRI). Dietary consumption was lowest for vitamins D and E, calcium, and magnesium. VM supplementation most improved intakes of vitamins E, D, B(6), folic acid, and calcium. Participants were most likely to exceed the Tolerable Upper Limit with supplementation of niacin, folic acid, and vitamin A.

  4. Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia.

    PubMed

    Ge, Zheng; Guo, Xing; Li, Jianyong; Hartman, Melanie; Kawasawa, Yuka Imamura; Dovat, Sinisa; Song, Chunhua

    2015-12-01

    Increased expression of c-MYC is observed in both Acute Myeloid Leukemia (AML) and T-cell Acute Lymphoblastic Leukemia (T-ALL). MYC binding protein 2 (MYCBP2) is a probable E3 ubiquitin ligase and its function in leukemia is unknown. IKZF1 deletion is associated with the development and poor outcome of ALL. Here, we observed significant high c-MYC expression and low MYCBP2 expression in adult ALL patients. Patients with high c-MYC expression and/or low MYCBP2 expression had higher WBC counts and a higher percentage of CD34+ or CD33+ cells, as well as splenomegaly, liver infiltration, higher BM blasts, and lower CR rate. Ikaros bound to the regulatory regions of c-MYC and MYCBP2, suppressed c-MYC and increased MYCBP2 expression in ALL cells. Expression of c-MYC mRNA was significantly higher in patients with IKZF1 deletion; conversely MYCBP2 mRNA expression was significantly lower in those patients. A CK2 inhibitor, which acts as an Ikaros activator, also suppressed c-MYC and increased MYCBP2 expression in an Ikaros (IKZF1) dependent manner in the ALL cells. In summary, our data indicated the correlation of high c-MYC expression, low MYCBP2 expression and high c-MYC plus low MYCBP2 expression with high-risk factors and proliferation markers in adult ALL patients. Our data also revealed an oncogenic role for an Ikaros/MYCBP2/c-MYC axis in adult ALL, providing a mechanism of target therapies that activate Ikaros in adult ALL.

  5. Use of Context in the Word Recognition Process by Adults with a Significant History of Reading Difficulties

    ERIC Educational Resources Information Center

    Corkett, Julie K.; Parrila, Rauno

    2008-01-01

    We examined whether university students who report a significant history of reading difficulties (RD; n=24) differed from university students with no history of reading difficulties (NRD; n=31) in how sentence context affects word recognition. Experiment 1 found no differences in how congruent sentence primes or syntactic manipulations of the…

  6. The Majority of Adult Pneumococcal Invasive Infections in Portugal Are Still Potentially Vaccine Preventable in Spite of Significant Declines of Serotypes 1 and 5

    PubMed Central

    Horácio, Andreia N.; Diamantino-Miranda, Jorge; Aguiar, Sandra I.; Ramirez, Mário; Melo-Cristino, José

    2013-01-01

    In Portugal, pneumococcal conjugate vaccines have been administered to children outside of the national immunization plan since 2001. We determined the serotype and antimicrobial susceptibility of 1265 isolates responsible for adult invasive pneumococcal infections (IPD) between 2009 and 2011 and compared the results with previously published data from 1999 to 2008. Serotypes 3 (12.6%), 7F (10.0%), 19A (9.1%), 14 (8.4%), 1 (6.9%) and 8 (6.2%) were the most frequent and together accounted for 53.2% of adult IPD. Serotypes 1 and 5 declined significantly while serotype 34, not included in any vaccine, increased. Taken together, the serotypes included in the 13-valent conjugate vaccine (PCV13) peaked among adult IPD isolates in 2008 (70.2%) and declined since then reaching 53.5% in 2011. The decline in the serotypes included in the 23-valent polysaccharide vaccine since 2007 was also significant but much more modest with 79.2% of the isolates causing IPD in 2011 expressing these serotypes. Since the changes in serotypes causing IPD in adults coincided with the 10-valent and PCV13 introduction in children, it is unlikely that vaccination triggered these changes although it may have accelerated them. The proportion of IPD caused by serotypes included in the 7-valent conjugate vaccine remained stable (19.0%). Both penicillin non-susceptibility and erythromycin resistance increased in the study period, with serotypes 14 and 19A accounting for the majority of resistant isolates. PMID:24066064

  7. The significance of the host inflammatory response on the therapeutic efficacy of cell therapies utilising human adult stem cells

    SciTech Connect

    Navarro, Melba; Pu, Fanrong; Hunt, John A.

    2012-02-15

    Controlling the fate of implanted hMSCs is one of the major drawbacks to be overcome to realize tissue engineering strategies. In particular, the effect of the inflammatory environment on hMSCs behaviour is poorly understood. Studying and mimicking the inflammatory process in vitro is a very complex and challenging task that involves multiple variables. This research addressed the questions using in vitro co-cultures of primary derived hMSCs together with human peripheral blood mononucleated cells (PBMCs); the latter are key agents in the inflammatory process. This work explored the in vitro phenotypic changes of hMSCs in co-culture direct contact with monocytes and lymphocytes isolated from blood using both basal and osteogenic medium. Our findings indicated that hMSCs maintained their undifferentiated phenotype and pluripotency despite the contact with PBMCs. Moreover, hMSCs demonstrated increased proliferation and were able to differentiate specifically down the osteogenic lineage pathway. Providing significant crucial evidence to support the hypothesis that inflammation and host defence mechanisms could be utilised rather than avoided and combated to provide for the successful therapeutic application of stem cell therapies.

  8. Significant correlations of dermal total carotenoids and dermal lycopene with their respective plasma levels in healthy adults

    PubMed Central

    Scarmo, Stephanie; Cartmel, Brenda; Lin, Haiqun; Leffell, David J.; Welch, Erin; Bhosale, Prakash; Bernstein, Paul S.; Mayne, Susan T.

    2010-01-01

    Carotenoids in skin have been known to play a role in photoprotection against UV radiation. We performed dermal biopsies of healthy humans (N=27) and collected blood samples for pair-wise correlation analyses of total and individual carotenoid content by high performance liquid chromatography (HPLC). The hydrocarbon carotenoids (lycopene and beta-carotene) made up the majority of carotenoids in both skin and plasma, and skin was somewhat enriched in these carotenoids relative to plasma. Beta-cryptoxanthin, a monohydroxycarotenoid, was found in similar proportions in skin as in plasma. In contrast, the dihydroxycarotenoids, lutein and zeaxanthin, were relatively lacking in human skin in absolute and relative levels as compared to plasma. Total carotenoids were significantly correlated in skin and plasma (r = 0.53, p<0.01). Our findings suggest that human skin is relatively enriched in lycopene and beta-carotene, compared to lutein and zeaxanthin, possibly reflecting a specific function of hydrocarbon carotenoids in human skin photoprotection. PMID:20637178

  9. Community perceptions on the significant extension of life: an exploratory study among urban adults in Brisbane, Australia.

    PubMed

    Underwood, Mair; Bartlett, Helen P; Partridge, Brad; Lucke, Jayne; Hall, Wayne D

    2009-02-01

    Some researchers in the field of ageing claim that significant extension of the human lifespan will be possible in the near future. While many of these researchers have assumed that the community will welcome this technology, there has been very little research on community attitudes to life extension. This paper presents the results of an in-depth qualitative study of community attitudes to life extension across age groups and religious boundaries. There were 57 individual interviews, and 8 focus groups (totalling 72 focus group participants) conducted with community members in Brisbane, Australia. Community attitudes to life extension were more varied and complex than have been assumed by some biogerontologists and bioethicists. While some participants would welcome the opportunity to extend their lives others would not even entertain the possibility. This paper details these differences of opinion and reveals contrasting positions that reflect individualism or social concern among community members. The findings also highlight the relationship between Christianity, in particular belief in an afterlife, and attitudes to life extension technology. Overall, the study raises questions about the relationship between interest in life extension, the medicalisation of ageing and the increasing acceptability of enhancement technologies that need to be addressed in more representative samples of the community.

  10. Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults

    PubMed Central

    Mather, Karen A.; Thalamuthu, Anbupalam; Oldmeadow, Christopher; Song, Fei; Armstrong, Nicola J.; Poljak, Anne; Holliday, Elizabeth G.; McEvoy, Mark; Kwok, John B.; Assareh, Amelia A.; Reppermund, Simone; Kochan, Nicole A.; Lee, Teresa; Ames, David; Wright, Margaret J.; Trollor, Julian N.; Schofield, Peter W.; Brodaty, Henry; Scott, Rodney J.; Schofield, Peter R.; Attia, John R.; Sachdev, Perminder S.

    2016-01-01

    Apolipoprotein H (ApoH) is a multi-functional plasma glycoprotein that has been associated with negative health outcomes. ApoH levels have high heritability. We undertook a genome-wide association study of ApoH levels using the largest sample to date and replicated the results in an independent cohort (total N = 1,255). In the discovery phase, a meta-analysis of two cohorts, the Sydney Memory and Ageing Study (Sydney MAS) and the Older Australian Twins Study (OATS) (n = 942) revealed genome-wide significant results in or near the APOH gene on chromosome 17 (top SNP, rs7211380, p = 1 × 10−11). The results were replicated in an independent cohort, the Hunter Community Study (p < 0.002) (n = 313). Conditional and joint analysis (COJO) confirmed the association of the chromosomal 17 region with ApoH levels. The set of independent SNPs identified by COJO explained 23% of the variance. The relationships between the top SNPs and cardiovascular/lipid/cognition measures and diabetes were assessed in Sydney MAS, with suggestive results observed for diabetes and cognitive performance. However, replication of these results in the smaller OATS cohort was not found. This work provides impetus for future research to better understand the contribution of genetics to ApoH levels and its possible impacts on health. PMID:27030319

  11. Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.

    PubMed

    Mather, Karen A; Thalamuthu, Anbupalam; Oldmeadow, Christopher; Song, Fei; Armstrong, Nicola J; Poljak, Anne; Holliday, Elizabeth G; McEvoy, Mark; Kwok, John B; Assareh, Amelia A; Reppermund, Simone; Kochan, Nicole A; Lee, Teresa; Ames, David; Wright, Margaret J; Trollor, Julian N; Schofield, Peter W; Brodaty, Henry; Scott, Rodney J; Schofield, Peter R; Attia, John R; Sachdev, Perminder S

    2016-01-01

    Apolipoprotein H (ApoH) is a multi-functional plasma glycoprotein that has been associated with negative health outcomes. ApoH levels have high heritability. We undertook a genome-wide association study of ApoH levels using the largest sample to date and replicated the results in an independent cohort (total N = 1,255). In the discovery phase, a meta-analysis of two cohorts, the Sydney Memory and Ageing Study (Sydney MAS) and the Older Australian Twins Study (OATS) (n = 942) revealed genome-wide significant results in or near the APOH gene on chromosome 17 (top SNP, rs7211380, p = 1 × 10(-11)). The results were replicated in an independent cohort, the Hunter Community Study (p < 0.002) (n = 313). Conditional and joint analysis (COJO) confirmed the association of the chromosomal 17 region with ApoH levels. The set of independent SNPs identified by COJO explained 23% of the variance. The relationships between the top SNPs and cardiovascular/lipid/cognition measures and diabetes were assessed in Sydney MAS, with suggestive results observed for diabetes and cognitive performance. However, replication of these results in the smaller OATS cohort was not found. This work provides impetus for future research to better understand the contribution of genetics to ApoH levels and its possible impacts on health. PMID:27030319

  12. Quantitative short-day photoperiodic response in larval development and its adaptive significance in an adult-overwintering cerambycid beetle, Phytoecia rufiventris.

    PubMed

    Shintani, Yoshinori

    2011-07-01

    The chrysanthemum longicorn beetle, Phytoecia rufiventris, overwinters in the adult stage and reproduces in spring. Larvae of this beetle develop during summer inside a host stem or root. In the present study, photoperiodic control of larval development and its adaptive significance were examined in this beetle using an artificial diet. Larvae showed a short-day photoperiodic response at 25°C with a critical day length of around 14 h; larvae reared under short-day conditions pupated, whereas those reared under long-day conditions entered summer diapause with some supernumerary molts and did not pupate. A similar response was found at 30°C, but with a shorter critical day length. Below the critical day length, a shorter day length corresponded to a shorter larval period. Larvae transferred from long-day conditions to various photoperiods showed a similar quantitative response. Field rearing of larvae starting at various times of year showed that pupation occurs within a relatively short period in early autumn. Field rearing of pupae and adults at various times indicated that only pupation in early autumn results in a high survival rate until winter. Earlier or later pupation led to a low survival rate due to death before overwintering in the adult and pupal stages, respectively. Thus, in P. rufiventris, timing of pupation regulated by the quantitative short-day photoperiodic response is vital for survival. Relatively lower developmental threshold in the pupal stage supports this hypothesis.

  13. An association, in adult Japanese, between the occurrence of rogue cells among cultured lymphocytes (JC virus activity) and the frequency of "simple" chromosomal damage among the lymphocytes of persons exhibiting these rogue cells.

    PubMed Central

    Neel, J V

    1998-01-01

    Data from a previous study of the cytogenetic effects, in cultured lymphocytes, of exposure to the atomic bomb in Hiroshima have been reanalyzed to determine the relationship between the occurrence of "rogue" cells in an individual and the frequency of "simple" chromosomal damage in the nonrogue cells of the same individual. Rogue cells are cells with complex chromosomal damage, currently believed to be a manifestation of the activity of a human polyoma virus termed "JC." Among a total of 1,835 persons examined, there were 45 exhibiting rogue cells. A total of 179,599 cells were scored for simple chromosomal damage. In both the exposed and the control populations, there was an absolute increase of approximately 1.5% in the frequency of simple chromosomal damage in the nonrogue cells of those exhibiting rogue cells, when compared with the frequencies observed in those not exhibiting rogue cells, which is a statistically significant difference. It is argued that this phenomenon, occurring not only in lymphocytes but possibly also in other cells/tissues, may play a contributory role in the origin of malignancies characterized by clonal chromosome abnormalities. Unexpectedly, among those exhibiting rogue cells, there was a disproportionately greater representation of persons who had received relatively high radiation exposures from the bomb. The reason for this is unclear, but it is tempting to relate the finding to some lingering effect of the exposure (or the circumstances surrounding the exposure) on immunocompetence. PMID:9683586

  14. Small non-polar complexes exhibiting significant piezoelectric properties: Solvothermal synthesis and crystal structures of MO{sub 5}V(tren){center_dot}H{sub 2}O (M=Mo and W; tren=tris(2-aminoethyl)amine)

    SciTech Connect

    Rasmussen, M.; Naether, C.; Bismayer, U.; Bensch, W.

    2012-11-15

    The two isostructural complexes MO{sub 5}V(tren){center_dot}H{sub 2}O (M=Mo (1) and W (2)) were synthesized under solvothermal conditions at pH Almost-Equal-To 12 crystallizing in the non-centrosymmetric space group P2{sub 1}2{sub 1}2{sub 1}. The structures are constructed by a distorted tetrahedral [MO{sub 4}]{sup 2-} anion bound via one shared oxygen atom to a severely distorted [V{sup IV}N{sub 4}O]{sup 2+} complex completing the octahedral coordination around the V centre. The two O atoms in the VN{sub 4}O{sub 2} octahedron are in cis position. The two compounds represent rare examples where the [MO{sub 4}]{sup 2-} anion is acting as a ligand. Both compounds exhibit a piezoelectric effect which is more pronounced for M=Mo. The samples are further characterized with IR and UV/Vis spectroscopy and thermal analysis. - Graphical abstract: The complexes [(V(tren)O)(MO4)]{center_dot}H2O (M = Mo, W; tren = tris(2-aminoethyl)amine)) composed of vertex-linked [MO4]{sup 2-} tetrahedron and [VN4O6]{sup 2+}octahedron. Highlights: Black-Right-Pointing-Pointer [MO{sub 4}]{sup 2-} tetrahedron (M=Mo, W) acting as ligand. Black-Right-Pointing-Pointer Jahn-Teller and steric distortion of the [VN{sub 4}O{sub 2}]{sup 2+} octahedron. Black-Right-Pointing-Pointer Non-centrosymmetric complexes exhibiting pronounced piezoelectric effect.

  15. Ethics on Exhibit

    ERIC Educational Resources Information Center

    Vick, Randy M.

    2011-01-01

    This article discusses ethical questions raised by an exhibition of work by an artist with a history of mental illness and the exhibition's relevance to art therapy and “outsider art” discourse on the subject. Considerations for how such an exhibit could be handled had the circumstances included an art therapist and art therapy client are…

  16. Single nucleotide polymorphism (SNP) analysis demonstrates a significant association of tumour necrosis factor-alpha (TNFA) with primary immune thrombocytopenia among Caucasian adults.

    PubMed

    Sarpatwari, Ameet; Bussel, James B; Ahmed, Momin; Erqou, Sebhat; Semple, John W; Newland, Adrian C; Bennett, Dimitri; Pharoah, Paul; Provan, Drew

    2011-07-01

    T-helper 1 polarization in patients with primary immune thrombocytopenia (ITP) is well documented. However, the genetic contribution to this imbalance remains unclear. To address this question, we selected six candidate single nucleotide polymorphisms within cytokine or cytokine receptor genes for association testing among Caucasian adults. Patients from the United Kingdom Adult ITP Registry were gender-matched (1:3) with healthy controls from the Wellcome Trust Case Control Consortium. Variants IL10 -819 c>t, TNFA -308 g>a, TGFB1 -509 c>t, IL1A -889 c>t, IL10 -592 c>t, and IL4R q576r were measured in cases and retrieved for controls from the European Genome-phenome Archive. Associations were evaluated using logistic regression models. In total, 206 patients with primary ITP were matched with 618 controls. A significant per allele odds ratio of 1·34 (95% confidence interval, 1·03-1·75; P = 0·03) was observed for TNFA -308 g>a, implicating an increased disease susceptibility among Caucasian carriers of the rare allele.

  17. BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal.

    PubMed

    Thapa, Lekhjung; Rana, P V S

    2016-01-01

    Objective. Nondiabetic obese individuals have subclinical involvement of peripheral nerves. We report the factors predicting peripheral nerve function in overweight and obese nondiabetic Nepalese individuals. Methodology. In this cross-sectional study, we included 50 adult overweight and obese nondiabetic volunteers without features of peripheral neuropathy and 50 healthy volunteers to determine the normative nerve conduction data. In cases of abnormal function, the study population was classified on the basis of the number of nerves involved, namely, "<2" or "≥2." Multivariable logistic regression analysis was carried out to predict outcomes. Results. Fasting blood glucose (FBG) was the significant predictor of motor nerve dysfunction (P = 0.039, 95% confidence interval (CI) = 1.003-1.127). Homeostatic model assessment of insulin resistance (HOMA-IR) was the significant predictor (P = 0.019, 96% CI = 1.420-49.322) of sensory nerve dysfunction. Body mass index (BMI) was the significant predictor (P = 0.034, 95% CI = 1.018-1.577) in case of ≥2 mixed nerves' involvement. Conclusion. FBG, HOMA-IR, and BMI were significant predictors of peripheral nerve dysfunction in overweight and obese Nepalese individuals. PMID:27200189

  18. The International Classification of Functioning, Disability and Health as a Framework for Providing Patient- and Family-Centered Audiological Care for Older Adults and Their Significant Others.

    PubMed

    Grenness, Caitlin; Meyer, Carly; Scarinci, Nerina; Ekberg, Katie; Hickson, Louise

    2016-08-01

    Hearing impairment is highly prevalent in the older population, and it impacts communication and quality of life for both the people with the hearing difficulties and their significant others. In this article, typical audiological assessment and management of an older adult is contrasted with a best practice approach wherein the World Health Organization's International Classification of Functioning, Disability and Health (ICF) framework is applied. The aim of the comparison is to demonstrate how the ICF expands our focus: rather than merely focusing on impairment, we also consider the activities, participation, and contextual factors for both the person with the hearing impairment and his or her family. A case example of an older patient and her spouse is provided, and their shared experience of the patient's hearing impairment is mapped onto the ICF framework. Family-centered hearing care is recommended for individualizing care and improving outcomes for older patients and their families. PMID:27489398

  19. An Evidence-Based Education Program for Adults about Child Sexual Abuse (“Prevent It!”) That Significantly Improves Attitudes, Knowledge, and Behavior

    PubMed Central

    Martin, Erin K.; Silverstone, Peter H.

    2016-01-01

    Here we describe the development of an evidence-based education program for adults about childhood sexual abuse (CSA), called Prevent It! Uniquely, the primary goal of this program was to change the behavior of participants, as well as to increase knowledge about CSA and positive attitudes toward it. A comprehensive review shows no previous similar approach. The program includes a detailed manual to allow standardized administration by trained facilitators, as well as multiple video segments from CSA survivors and professionals. A total of 23 program workshops were run, with 366 adults participating. Of these, 312 (85%) agreed to take part in the study. All completed baseline ratings prior to the program and 195 (63% of study sample) completed follow-up assessments at 3-months. There were no significant differences between the demographic make-up of the baseline group and the follow-up group. Assessments included demographic data, knowledge, attitudes, and several measures of behavior (our primary outcome variable). Behavioral questions asked individuals to select behaviors used in the previous 3-months from a list of options. Questions also included asking “how many times in the previous 3-months” have you “talked about healthy sexual development or Child sexual abuse (CSA) with a child you know”; “suspected a child was sexually abused”; “taken steps to protect a child”; or “reported suspected sexual abuse to police or child welfare”? The majority of attendees were women, with the commonest age group being between 30 and 39 years old. Approximately 33% had experienced CSA themselves. At 3-month follow-up there were highly statistically significant improvements in several aspects of behavior and knowledge, and attitudes regarding CSA. For example, the number of subjects actively looking for evidence of CSA increased from 46% at baseline to 81% at follow-up, while the number of subjects who actively took steps to protect children increased from

  20. An Evidence-Based Education Program for Adults about Child Sexual Abuse (“Prevent It!”) That Significantly Improves Attitudes, Knowledge, and Behavior

    PubMed Central

    Martin, Erin K.; Silverstone, Peter H.

    2016-01-01

    Here we describe the development of an evidence-based education program for adults about childhood sexual abuse (CSA), called Prevent It! Uniquely, the primary goal of this program was to change the behavior of participants, as well as to increase knowledge about CSA and positive attitudes toward it. A comprehensive review shows no previous similar approach. The program includes a detailed manual to allow standardized administration by trained facilitators, as well as multiple video segments from CSA survivors and professionals. A total of 23 program workshops were run, with 366 adults participating. Of these, 312 (85%) agreed to take part in the study. All completed baseline ratings prior to the program and 195 (63% of study sample) completed follow-up assessments at 3-months. There were no significant differences between the demographic make-up of the baseline group and the follow-up group. Assessments included demographic data, knowledge, attitudes, and several measures of behavior (our primary outcome variable). Behavioral questions asked individuals to select behaviors used in the previous 3-months from a list of options. Questions also included asking “how many times in the previous 3-months” have you “talked about healthy sexual development or Child sexual abuse (CSA) with a child you know”; “suspected a child was sexually abused”; “taken steps to protect a child”; or “reported suspected sexual abuse to police or child welfare”? The majority of attendees were women, with the commonest age group being between 30 and 39 years old. Approximately 33% had experienced CSA themselves. At 3-month follow-up there were highly statistically significant improvements in several aspects of behavior and knowledge, and attitudes regarding CSA. For example, the number of subjects actively looking for evidence of CSA increased from 46% at baseline to 81% at follow-up, while the number of subjects who actively took steps to protect children increased from

  1. An Evidence-Based Education Program for Adults about Child Sexual Abuse ("Prevent It!") That Significantly Improves Attitudes, Knowledge, and Behavior.

    PubMed

    Martin, Erin K; Silverstone, Peter H

    2016-01-01

    Here we describe the development of an evidence-based education program for adults about childhood sexual abuse (CSA), called Prevent It! Uniquely, the primary goal of this program was to change the behavior of participants, as well as to increase knowledge about CSA and positive attitudes toward it. A comprehensive review shows no previous similar approach. The program includes a detailed manual to allow standardized administration by trained facilitators, as well as multiple video segments from CSA survivors and professionals. A total of 23 program workshops were run, with 366 adults participating. Of these, 312 (85%) agreed to take part in the study. All completed baseline ratings prior to the program and 195 (63% of study sample) completed follow-up assessments at 3-months. There were no significant differences between the demographic make-up of the baseline group and the follow-up group. Assessments included demographic data, knowledge, attitudes, and several measures of behavior (our primary outcome variable). Behavioral questions asked individuals to select behaviors used in the previous 3-months from a list of options. Questions also included asking "how many times in the previous 3-months" have you "talked about healthy sexual development or Child sexual abuse (CSA) with a child you know"; "suspected a child was sexually abused"; "taken steps to protect a child"; or "reported suspected sexual abuse to police or child welfare"? The majority of attendees were women, with the commonest age group being between 30 and 39 years old. Approximately 33% had experienced CSA themselves. At 3-month follow-up there were highly statistically significant improvements in several aspects of behavior and knowledge, and attitudes regarding CSA. For example, the number of subjects actively looking for evidence of CSA increased from 46% at baseline to 81% at follow-up, while the number of subjects who actively took steps to protect children increased from 25% at baseline to 48

  2. An Evidence-Based Education Program for Adults about Child Sexual Abuse ("Prevent It!") That Significantly Improves Attitudes, Knowledge, and Behavior.

    PubMed

    Martin, Erin K; Silverstone, Peter H

    2016-01-01

    Here we describe the development of an evidence-based education program for adults about childhood sexual abuse (CSA), called Prevent It! Uniquely, the primary goal of this program was to change the behavior of participants, as well as to increase knowledge about CSA and positive attitudes toward it. A comprehensive review shows no previous similar approach. The program includes a detailed manual to allow standardized administration by trained facilitators, as well as multiple video segments from CSA survivors and professionals. A total of 23 program workshops were run, with 366 adults participating. Of these, 312 (85%) agreed to take part in the study. All completed baseline ratings prior to the program and 195 (63% of study sample) completed follow-up assessments at 3-months. There were no significant differences between the demographic make-up of the baseline group and the follow-up group. Assessments included demographic data, knowledge, attitudes, and several measures of behavior (our primary outcome variable). Behavioral questions asked individuals to select behaviors used in the previous 3-months from a list of options. Questions also included asking "how many times in the previous 3-months" have you "talked about healthy sexual development or Child sexual abuse (CSA) with a child you know"; "suspected a child was sexually abused"; "taken steps to protect a child"; or "reported suspected sexual abuse to police or child welfare"? The majority of attendees were women, with the commonest age group being between 30 and 39 years old. Approximately 33% had experienced CSA themselves. At 3-month follow-up there were highly statistically significant improvements in several aspects of behavior and knowledge, and attitudes regarding CSA. For example, the number of subjects actively looking for evidence of CSA increased from 46% at baseline to 81% at follow-up, while the number of subjects who actively took steps to protect children increased from 25% at baseline to 48

  3. A Teaching Aids Exhibition.

    ERIC Educational Resources Information Center

    Mahanja, Salah

    1985-01-01

    Describes an exhibition for the benefit of teachers of English in Arab Primary Schools, which was prepared by third-year students at the Teachers College for Arab Teachers. The exhibition included games, songs, audiovisual aids, crossword puzzles, vocabulary, spelling booklets, preposition aids, and worksheet and lesson planning aids. (SED)

  4. Communicating Science through Exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, P.; Harold, J.; Morrow, C.

    It is critically important for the public to better understand the scientific process. Museum exhibitions are an important part of informal science education that can effectively reach public audiences as well as school groups. They provide an important gateway for the public to learn about compelling scientific endeavors. There are many ways for scientists to help develop science exhibitions. The Space Science Institute (SSI) is a national leader in producing traveling science exhibitions and their associated educational programming (i.e. interactive websites, educator workshops, public talks, instructional materials). Two of its exhibitions, Space Weather Center and MarsQuest, are currently on tour. Another exhibition, Alien Earths, is in development. The Space Weather Center was developed in partnership with various research missions at NASA's Goddard Space Flight Center. MarsQuest is a 5000 square-foot traveling exhibition. The exhibit's second 3-year tour began this January at the Detroit Science Center. It is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and to learn more about their own planet in the process. The 3,000 square-foot traveling exhibition, called Alien Earths, will bring origins-related research and discoveries to students and the American public. Alien Earths has four interrelated exhibit areas: Our Place in Space, Star Birth, PlanetQuest, and Search for Life. Exhibit visitors will explore the awesome events surrounding the birth of stars and planets; they will join scientists in the hunt for planets outside our solar system including those that may be in ``habitable zones'' around other stars; and finally they will be able to learn about how scientists are looking for signs of life beyond Earth. Besides the exhibits, SSI is also developing interactive web sites based on exhibit themes. New technologies are transforming the Web from a static medium to an interactive environment with tremendous

  5. Varying protein source and quantity does not significantly improve weight loss, fat loss, or satiety in reduced energy diets amongmidlife adults.1

    PubMed Central

    Aldrich, Noel D; Reicks, Marla M; Sibley, Shalamar D; Redmon, J Bruce; Thomas, William; Raatz, Susan K

    2011-01-01

    We hypothesized that a whey protein diet would result in greater weight loss and improved body compositioncompared to standard weight loss diets. Weight change, body composition, and renin angiotensin aldosterone system activity in midlife adults was compared between diet groups. Eighteen subjects enrolled ina5 month study of8 weeks controlled food intake followed by 12 weeks ad libitum intake. Subjects were randomized to one of three treatment groups: control diet (CD) (55% carbohydrate: 15% protein: 30% fat), mixed protein (MP) (40% carbohydrate: 30% protein: 30% fat), or whey protein (WP) (40% carbohydrate: 15% mixed protein: 15% whey protein: 30% fat). Measurements included weight, metabolic measures, body composition by dual energy x-ray absorptiometry (DXA), and resting energy expenditure. No statistically significant differences in total weight loss or total fat loss were observed between treatments, however, a trend toward greater total weight loss (p = 0.08) and total fat loss (p=0.09) was observed in the WP group compared to the CD group. Fat loss in the leg and gynoid regions was greater (p < 0.05) in the WP group than the CD group. No RAAS mediated response was observed, but a decrease in systolic blood pressure was significantly greater (p <0.05) in the WP group compared to the CD group. In summary, increased whey protein intake did not result in statistically significant differences in weight loss or in total fat loss, but significant differences in regional fat loss and in decreased blood pressure were observed in the WP group. PMID:21419314

  6. New Hurricane Exhibit

    NASA Technical Reports Server (NTRS)

    2007-01-01

    A new exhibit in StenniSphere depicting NASA's role in hurricane prediction and research and SSC's role in helping the region recover from Hurricane Katrina. The cyclone-shaped exhibit focuses on the effects of the Aug. 29, 2005 storm and outlines how NASA is working to improve weather forecasting. Through photos, 3-D models and digital animations, the exhibit tells the story of what happened inside the storm and how NASA's scientific research can increase the accuracy of hurricane tracking and modeling.

  7. Test Control Center exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.

  8. Communicating Science through Exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, Paul

    2005-04-01

    It is critically important for the public to better understand the scientific process. Museum exhibitions are an important part of informal science education that can effectively reach public audiences as well as school groups. They provide an important gateway for the public to learn about compelling scientific endeavors. Science exhibitions also provide a marvelous opportunity for scientists to become engaged in the exhibit development process. The Space Science Institute (SSI) is a national leader in producing traveling science exhibitions and their associated educational programming (i.e. interactive websites, educator workshops, public talks, instructional materials). The focus of this presentation will be on two of its exhibit projects: MarsQuest (on tour for four years) and Alien Earths (its tour began early in 2005). MarsQuest is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and to learn more about their own planet in the process. Alien Earths will bring origins-related research and discoveries to students and the American public. It has four interrelated exhibit areas: Our Place in Space, Star Birth, Planet Quest, and Search for Life. Exhibit visitors will explore the awesome events surrounding the birth of stars and planets; they will join scientists in the hunt for planets outside our solar system including those that may be in ``habitable zones'' around other stars; and finally they will be able to learn about how scientists are looking for signs of life beyond Earth. SSI is also developing interactive web sites based on exhibit themes. New technologies are transforming the Web from a static medium to an interactive environment with tremendous potential for informal education and inquiry-based investigations. This talk will focus on the role informal science projects play in effectively communicating science to a broad, public audience.

  9. Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia

    PubMed Central

    Mrózek, Krzysztof; Marcucci, Guido; Nicolet, Deedra; Maharry, Kati S.; Becker, Heiko; Whitman, Susan P.; Metzeler, Klaus H.; Schwind, Sebastian; Wu, Yue-Zhong; Kohlschmidt, Jessica; Pettenati, Mark J.; Heerema, Nyla A.; Block, AnneMarie W.; Patil, Shivanand R.; Baer, Maria R.; Kolitz, Jonathan E.; Moore, Joseph O.; Carroll, Andrew J.; Stone, Richard M.; Larson, Richard A.; Bloomfield, Clara D.

    2012-01-01

    Purpose To evaluate the prognostic significance of the international European LeukemiaNet (ELN) guidelines for reporting genetic alterations in acute myeloid leukemia (AML). Patients and Methods We analyzed 1,550 adults with primary AML, treated on Cancer and Leukemia Group B first-line trials, who had pretreatment cytogenetics and, for cytogenetically normal patients, mutational status of NPM1, CEBPA, and FLT3 available. We compared complete remission (CR) rates, disease-free survival (DFS), and overall survival (OS) among patients classified into the four ELN genetic groups (favorable, intermediate-I, intermediate-II, adverse) separately for 818 younger (age < 60 years) and 732 older (age ≥ 60 years) patients. Results The percentages of younger versus older patients in the favorable (41% v 20%; P < .001), intermediate-II (19% v 30%; P < .001), and adverse (22% v 31%; P < .001) genetic groups differed. The favorable group had the best and the adverse group the worst CR rates, DFS, and OS in both age groups. Both intermediate groups had significantly worse outcomes than the favorable but better than the adverse group. Intermediate-I and intermediate-II groups in older patients had similar outcomes, whereas the intermediate-II group in younger patients had better OS but not better CR rates or DFS than the intermediate-I group. The prognostic significance of ELN classification was confirmed by multivariable analyses. For each ELN group, older patients had worse outcomes than younger patients. Conclusion The ELN classification clearly separates the genetic groups by outcome, supporting its use for risk stratification in clinical trials. Because they have different proportions of genetic alterations and outcomes, younger and older patients should be reported separately when using the ELN classification. PMID:22987078

  10. The Clinical Significance of Glycoprotein Phospholipase D Levels in Distinguishing Early Stage Latent Autoimmune Diabetes in Adults and Type 2 Diabetes

    PubMed Central

    Qin, Wen; Liang, Yu-Zhen; Qin, Bao-Yu; Zhang, Jia-Li; Xia, Ning

    2016-01-01

    Autoantibodies have been widely used as markers of latent autoimmune diabetes in adults (LADA); however, the specificity and sensitivity of autoantibodies as markers of LADA are weak compared with those found in type 1 diabetes (T1DM). In this study, we aimed to identify other plasma proteins as potential candidates that can be used effectively to determine early stage LADA and type 2 diabetes (T2DM) to facilitate early diagnosis and treatment. These issues were addressed by studying new-onset ‘classic’ T1DM (n = 156), LADA (n = 174), T2DM (n = 195) and healthy cohorts (n = 166). Plasma samples were obtained from the four cohorts. We employed isobaric tag for relative and absolute quantitation (iTRAQ) together with liquid chromatography tandem mass spectrometry (LC-MS) to identify plasma proteins with significant changes in LADA. The changes were validated by Western blot and ELISA analyses. Among the four cohorts, 311 unique proteins were identified in three iTRAQ runs, with 157 present across the three data sets. Among them, 49/311 (16.0%) proteins had significant changes in LADA compared with normal controls, including glycoprotein phospholipase D (GPLD1), which was upregulated in LADA. Western blot and ELISA analyses showed that GPLD1 levels were higher in both LADA and T1DM cohorts than in both T2DM and healthy cohorts, while there were no significant differences in the plasma concentrations of GPLD1 between the LADA and T1DM cohorts. GPLD1 is implicated as a potential candidate plasma protein for determining early stage LADA and T2DM. PMID:27351175

  11. 76 FR 52378 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Featuring Selections From the National Museum of History, Taiwan and the Arthur M. Sackler Gallery... Jade Featuring Selections from the National Museum of History, Taiwan and the Arthur M. Sackler Gallery... Art, San Antonio, TX, from on or about October 1, 2011, until on or about February 19, 2012, and...

  12. Specific combinations of the chromatin-modifying enzyme modulators significantly attenuate glioblastoma cell proliferation and viability while exerting minimal effect on normal adult stem cells growth.

    PubMed

    Alexanian, Arshak R; Huang, Yi-Wen

    2015-11-01

    The discoveries of recent decade showed that all critical changes in cancer cells, such as silencing of tumor-suppressor genes and activation of oncogenes, are caused not only by genetic but also by epigenetic mechanisms. Although epigenetic changes are somatically heritable, in contrast to genetic changes, they are potentially reversible, making them good targets for therapeutic intervention. Covalent modifications of chromatin such as methylation and acetylation of histones and methylation of DNA are the important components of epigenetic machinery. In this study, we investigated the effect of different modulators of DNA and histone covalent-modifying enzymes on the proliferation and viability of normal adult stem cells, such as human bone marrow mesenchymal stem cells (hMSCs), and on malignant tumor cells, such as glioblastoma (GB) D54 cells. Results demonstrated that specific combinations of histone methyltransferases and deacetylases inhibitors significantly attenuated D54 cells viability but having only a small effect on hMSCs growth. Taken together, these studies suggest that specific combinations of histone covalent modifiers could be an effective treatment option for the most aggressive type of primary brain tumors such as glioblastoma multiforme.

  13. Consumption of a healthy dietary pattern results in significant reductions in C-reactive protein levels in adults: a meta-analysis.

    PubMed

    Neale, E P; Batterham, M J; Tapsell, L C

    2016-05-01

    Consumption of healthy dietary patterns has been associated with reduced risk of cardiovascular disease and metabolic syndrome. Dietary intervention targets disease prevention, so studies increasingly use biomarkers of underlying inflammation and metabolic syndrome progression to examine the diet-health relationship. The extent to which these biomarkers contribute to the body of evidence on healthy dietary patterns is unknown. The aim of this meta-analysis was to determine the effect of healthy dietary patterns on biomarkers associated with adiposity, insulin resistance, and inflammation in adults. A systematic search of Scopus, PubMed, Web of Science, and Cochrane Central Register of Controlled Trials (all years to April 2015) was conducted. Inclusion criteria were randomized controlled trials; effects of dietary patterns assessed on C-reactive protein (CRP), total adiponectin, high-molecular-weight adiponectin, tumor necrosis factor-α, adiponectin:leptin, resistin, or retinol binding protein 4. Random effects meta-analyses were conducted to assess the weighted mean differences in change or final mean values for each outcome. Seventeen studies were included in the review. These reflected research on dietary patterns associated with the Mediterranean diet, Nordic diet, Tibetan diet, and the Dietary Approaches to Stop Hypertension diet. Consumption of a healthy dietary pattern was associated with significant reductions in CRP (weighted mean difference, -0.75 [-1.16, -0.35]; P = .0003). Non-significant changes were found for all other biomarkers. This analysis found evidence for favorable effects of healthy dietary patterns on CRP, with limited evidence for other biomarkers. Future research should include additional randomized controlled trials incorporating a greater range of dietary patterns and biomarkers. PMID:27101757

  14. Swamp to Space exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The menacing-looking alligator is really harmless. It is one of the realistic props to help convince visitors that the feel of the swamp is real in StenniSphere's Swamp to Space exhibit at John C. Stennis Space Center in Hancock County, Miss. The historical section of the Swamp to Space exhibit tells the story of why and how Stennis Space Center came to be. It also pays tribute to the families who moved their homes to make way for the space age in Mississippi.

  15. Exhibition in Sight

    ERIC Educational Resources Information Center

    Wasserman, Burton

    1978-01-01

    Ludwig Mies van der Rohe is known primarily as an architect. However, he also designed chairs and tables. Discusses an exhibit held in New York City a few months ago which showed how well the famous architect achieved his goals in the area of furniture design. (Author/RK)

  16. Exhibition in Sight

    ERIC Educational Resources Information Center

    Wasserman, Burton

    1978-01-01

    One of the most offbeat exhibitions presented in the last several years was the widely celebrated Warhol-Wyeth duo show, "Portraits of Each Other", held at the Brandywine River Museum in Chadds Ford, Pennsylvania. Discusses their paintings and their diametrically different personalities. (Author/RK)

  17. Significant long-term, but not short-term, hippocampal-dependent memory impairment in adult rats exposed to alcohol in early postnatal life.

    PubMed

    Goodfellow, Molly J; Lindquist, Derick H

    2014-09-01

    In rodents, ethanol exposure in early postnatal life is known to induce structural and functional impairments throughout the brain, including the hippocampus. Herein, rat pups were administered one of three ethanol doses over postnatal days (PD) 4-9, a period of brain development comparable to the third trimester of human pregnancy. As adults, control and ethanol rats were trained and tested in a variant of hippocampal-dependent one-trial context fear conditioning. In Experiment 1, subjects were placed into a novel context and presented with an immediate footshock (i.e., within ∼8 sec). When re-exposed to the same context 24 hr later low levels of conditioned freezing were observed. Context pre-exposure 24 hr prior to the immediate shock reversed the deficit in sham-intubated and unintubated control rats, enhancing freezing behavior during the context retention test. Even with context pre-exposure, however, significant dose-dependent reductions in contextual freezing were seen in ethanol rats. In Experiment 2, the interval between context pre-exposure and the immediate shock was shortened to 2 hr, in addition to the standard 24 hr. Ethanol rats trained with the 2 hr, but not 24 hr, interval displayed retention test freezing levels roughly equal to controls. Results suggest the ethanol rats can encode a short-term context memory and associate it with the aversive footshock 2 hr later. In the 24 hr ethanol rats the short-term context memory is poorly transferred or consolidated into long-term memory, we propose, impeding the memory's subsequent retrieval and association with shock.

  18. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows onlookers viewing displays within the Starship 2040 exhibit on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  19. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows Justin Varnadore, son of a Marshall TV employee, at the controls of one of the many displays within the Starship 2040 exhibit on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  20. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This photograph shows the Starship 2040 leaving the Marshall Space Flight Center (MSFC) for the exhibit site. Developed by the Space Transportation Directorate at MSFC, the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit, automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids and emergency and safety systems, are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  1. Online Exhibits & Concept Maps

    NASA Astrophysics Data System (ADS)

    Douma, M.

    2009-12-01

    Presenting the complexity of geosciences to the public via the Internet poses a number of challenges. For example, utilizing various - and sometimes redundant - Web 2.0 tools can quickly devour limited time. Do you tweet? Do you write press releases? Do you create an exhibit or concept map? The presentation will provide participants with a context for utilizing Web 2.0 tools by briefly highlighting methods of online scientific communication across several dimensions. It will address issues of: * breadth and depth (e.g. from narrow topics to well-rounded views), * presentation methods (e.g. from text to multimedia, from momentary to enduring), * sources and audiences (e.g. for experts or for the public, content developed by producers to that developed by users), * content display (e.g. from linear to non-linear, from instructive to entertaining), * barriers to entry (e.g. from an incumbent advantage to neophyte accessible, from amateur to professional), * cost and reach (e.g. from cheap to expensive), and * impact (e.g. the amount learned, from anonymity to brand awareness). Against this backdrop, the presentation will provide an overview of two methods of online information dissemination, exhibits and concept maps, using the WebExhibits online museum (www.webexhibits.org) and SpicyNodes information visualization tool (www.spicynodes.org) as examples, with tips on how geoscientists can use either to communicate their science. Richly interactive online exhibits can serve to engage a large audience, appeal to visitors with multiple learning styles, prompt exploration and discovery, and present a topic’s breadth and depth. WebExhibits, which was among the first online museums, delivers interactive information, virtual experiments, and hands-on activities to the public. While large, multidisciplinary exhibits on topics like “Color Vision and Art” or “Calendars Through the Ages” require teams of scholars, user interface experts, professional writers and editors

  2. Space Shuttle Cockpit exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Want to sit in the cockpit of the Space Shuttle and watch astronauts work in outer space? At StenniSphere, you can do that and much more. StenniSphere, the visitor center at John C. Stennis Space Center in Hancock County, Miss., presents 14,000-square-feet of interactive exhibits that depict America's race for space as well as a glimpse of the future. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  3. Smithsonian climate change exhibits

    NASA Astrophysics Data System (ADS)

    Kumar, Mohi

    2006-05-01

    Two new museum exhibits, ``Arctic: A Friend Acting Strangely'' and ``Atmosphere: Change is in the Air'' opened 15 April at the Smithsonian Institution's National Museum of Natural History in Washington, D.C., in partnership with the U.S. National Oceanic and Atmospheric Administration, NASA, and the U.S. National Science Foundation. In ``Arctic: A Friend Acting Strangely,'' anecdotes from indigenous polar people reveal how climate changes have affected life within the last 50 years. For example, as permafrost melts and sea ice shrinks, plant distributions and animal migration patterns are changing, severely affecting culture.

  4. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows the Starship 2040 on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  5. Maurice Gee's Brilliant Borrowings of Maurice Gee and Significant Others: Realism and Postmodernism in Gee's Books for Children and Adults

    ERIC Educational Resources Information Center

    van Rij, Vivien

    2013-01-01

    This paper examines the work of one of New Zealand's most acclaimed writers, Maurice Gee, and the use of his children's fiction as an experimental ground for postmodernist techniques further developed in his writing for adults. In particular, it considers Gee's borrowings of his own and others' non-fictional and fictional…

  6. Sex differences in science museum exhibit attraction

    NASA Astrophysics Data System (ADS)

    Arámbula Greenfield, Teresa

    This study examines the relative attraction of hands-on, interactive science museum exhibits for females and males. Studies have demonstrated that such exhibits can be effective learning experiences for children, with both academic and affective benefits. Other studies have shown that girls and boys do not always experience the same science-related educational opportunities and that, even when they do, they do not necessarily receive the same benefits from them. These early differences can lead to more serious educational and professional disparities later in life. As interactive museum exhibits represent a science experience that is-readily available to both girls and boys, the question arose as to whether they were being used similarly by the two groups as well as by adult women and men. It was found that both girls and boys used all types of exhibits, but that girls were more likely than boys to use puzzles and exhibits focusing on the human body; boys were more likely than girls to use computers and exhibits illustrating physical science principles. However, this was less true of children accompanied by adults (parents) than it was of unaccompanied children on school field trips who roamed the museum more freely.Received: 16 February 1994; Revised: 3 February 1995;

  7. Gifted Kids Create a Large Scale Museum Exhibit in Indianapolis.

    ERIC Educational Resources Information Center

    Waters, Mary Lou; Bostwick, Alice

    1989-01-01

    Indianapolis gifted students in grades five-seven created a museum exhibit to express the views of youth while giving adults an opportunity to listen. The process involved brainstorming, selecting a topic (drug and alcohol abuse), gathering information, forming committees, building a scale model, and creating the actual exhibit. (JDD)

  8. Early Hospital Mortality among Adult Trauma Patients Significantly Declined between 1998-2011: Three Single-Centre Cohorts from Mumbai, India

    PubMed Central

    Gerdin, Martin; Roy, Nobhojit; Dharap, Satish; Kumar, Vineet; Khajanchi, Monty; Tomson, Göran; Tsai, Li Felländer; Petzold, Max; von Schreeb, Johan

    2014-01-01

    Background Traumatic injury causes more than five million deaths each year of which about 90% occur in low- and middle-income countries (LMIC). Hospital trauma mortality has been significantly reduced in high-income countries, but to what extent similar results have been achieved in LMIC has not been studied in detail. Here, we assessed if early hospital mortality in patients with trauma has changed over time in an urban lower middle-income setting. Methods We conducted a retrospective study of patients admitted due to trauma in 1998, 2002, and 2011 to a large public hospital in Mumbai, India. Our outcome measure was early hospital mortality, defined as death between admission and 24-hours. We used multivariate logistic regression to assess the association between time and early hospital mortality, adjusting for patient case-mix. Injury severity was quantified using International Classification of Diseases-derived Injury Severity Score (ICISS). Major trauma was defined as ICISS<0.90. Results We analysed data on 4189 patients out of which 86.5% were males. A majority of patients were between 15 and 55 years old and 36.5% had major trauma. Overall early hospital mortality was 8.9% in 1998, 6.0% in 2002, and 8.1% in 2011. Among major trauma patients, early hospital mortality was 13.4%, in 1998, 11.3% in 2002, and 10.9% in 2011. Compared to trauma patients admitted in 1998, those admitted in 2011 had lower odds for early hospital mortality (OR = 0.56, 95% CI = 0.41–0.76) including those with major trauma (OR = 0.57, 95% CI = 0.41–0.78). Conclusions We observed a significant reduction in early hospital mortality among patients with major trauma between 1998 and 2011. Improved survival was evident only after we adjusted for patient case-mix. This finding highlights the importance of risk-adjustment when studying longitudinal mortality trends. PMID:24594775

  9. [All-Russian hygienic exhibitions and museums].

    PubMed

    Kuzybaeva, M P

    2011-01-01

    The material about the popularization of hygiene and health education in Russia in the second half of the 19th century to early 20th century through exhibition and museum activities has been collected for the first time and analyzed in the paper. The role of scientists and scientific medical societies in this process is noted. The significance of museum and exhibition activities in this area for the development of medical science is defined.

  10. Randomised, single-masked non-inferiority trial of femtosecond laser-assisted versus manual phacoemulsification cataract surgery for adults with visually significant cataract: the FACT trial protocol

    PubMed Central

    Day, Alexander C; Burr, Jennifer M; Bunce, Catey; Doré, Caroline J; Sylvestre, Yvonne; Wormald, Richard P L; Round, Jeff; McCudden, Victoria; Rubin, Gary; Wilkins, Mark R

    2015-01-01

    Introduction Cataract is one of the leading causes of low vision in the westernised world, and cataract surgery is one of the most commonly performed operations. Laser platforms for cataract surgery are now available, the anticipated advantages of which are broad and may include better visual outcomes through greater precision and reproducibility, and improved safety. FACT is a randomised single masked non-inferiority trial to establish whether laser-assisted cataract surgery is as good as or better than standard manual phacoemulsification. Methods and analysis 808 patients aged 18 years and over with visually significant cataract will be randomised to manual phacoemulsification cataract surgery (standard care) or laser-assisted cataract surgery (intervention arm). Outcomes will be measured at 3 and 12 months after surgery. The primary clinical outcome is uncorrected distance visual acuity (UDVA, logMAR) at 3 months in the study eye recorded by an observer masked to the trial group. Secondary outcomes include UDVA at 12 months, corrected distance visual acuity at 3 and 12 months, complications, endothelial cell loss, patient-reported outcome measures and a health economic analysis conforming to National Institute for Health and Care Excellence standards. Ethics and dissemination Research Ethics Committee Approval was obtained on 6 February 2015, ref: 14/LO/1937. Current protocol: v2.0 (08/04/2015). Study findings will be published in peer-reviewed journals. Trial registration number ISRCTN: 77602616. PMID:26614627

  11. Environmental enrichment for a mixed-species nocturnal mammal exhibit.

    PubMed

    Clark, Fay E; Melfi, Vicky A

    2012-01-01

    Environmental enrichment (EE) is an integral aspect of modern zoo animal management but, empirical evaluation of it is biased toward species housed in single-species groups. Nocturnal houses, where several nocturnal species are housed together, are particularly overlooked. This study investigated whether three species (nine-banded armadillos, Dasypus novemcinctus; Senegal bush babies, Galago senegalensis; two-toed sloths, Choloepus didactylus) in the nocturnal house at Paignton Zoo Environmental Park, UK could be enriched using food-based and sensory EE. Subjects were an adult male and female of each species. EE was deemed effective if it promoted target species-typical behaviors, behavioral diversity, and increased use of enriched exhibit zones. Results from generalized linear mixed models demonstrated that food-based EE elicited the most positive behavioral effects across species. One set of food-based EEs (Kong®, termite mound and hanging food) presented together was associated with a significant increase in species-typical behaviors, increased behavioral diversity, and increased use of enriched exhibit zones in armadillos and bush babies. Although one type of sensory EE (scented pine cones) increased overall exhibit use in all species, the other (rainforest sounds) was linked to a significant decrease in species-typical behavior in bush babies and sloths. There were no intra or interspecies conflicts over EE, and commensalism occurred between armadillos and bush babies. Our data demonstrate that simple food-based and sensory EE can promote positive behavioral changes in a mixed-species nocturnal mammal exhibit. We suggest that both food and sensory EE presented concurrently will maximize opportunities for naturalistic activity in all species.

  12. Environmental enrichment for a mixed-species nocturnal mammal exhibit.

    PubMed

    Clark, Fay E; Melfi, Vicky A

    2012-01-01

    Environmental enrichment (EE) is an integral aspect of modern zoo animal management but, empirical evaluation of it is biased toward species housed in single-species groups. Nocturnal houses, where several nocturnal species are housed together, are particularly overlooked. This study investigated whether three species (nine-banded armadillos, Dasypus novemcinctus; Senegal bush babies, Galago senegalensis; two-toed sloths, Choloepus didactylus) in the nocturnal house at Paignton Zoo Environmental Park, UK could be enriched using food-based and sensory EE. Subjects were an adult male and female of each species. EE was deemed effective if it promoted target species-typical behaviors, behavioral diversity, and increased use of enriched exhibit zones. Results from generalized linear mixed models demonstrated that food-based EE elicited the most positive behavioral effects across species. One set of food-based EEs (Kong®, termite mound and hanging food) presented together was associated with a significant increase in species-typical behaviors, increased behavioral diversity, and increased use of enriched exhibit zones in armadillos and bush babies. Although one type of sensory EE (scented pine cones) increased overall exhibit use in all species, the other (rainforest sounds) was linked to a significant decrease in species-typical behavior in bush babies and sloths. There were no intra or interspecies conflicts over EE, and commensalism occurred between armadillos and bush babies. Our data demonstrate that simple food-based and sensory EE can promote positive behavioral changes in a mixed-species nocturnal mammal exhibit. We suggest that both food and sensory EE presented concurrently will maximize opportunities for naturalistic activity in all species. PMID:21387395

  13. Exhibitions: Facing Outward, Pointing Inward

    ERIC Educational Resources Information Center

    McDonald, Joseph P.

    2007-01-01

    The Coalition of Essential Schools (CES) Exhibitions Project of the early 1990s produced a range of work that continues to inform the practice of using exhibitions as a "360 degree" method of transforming teaching and learning, community connections, school design, and assessment. Among that work was this paper coupling the origins of exhibitions…

  14. Gender and Single Nucleotide Polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 Are Significant Predictors of Plasma Homocysteine Normalized by RBC Folate in Healthy Adults123

    PubMed Central

    Clifford, Andrew J.; Chen, Kehui; McWade, Laura; Rincon, Gonzalo; Kim, Seung-Hyun; Holstege, Dirk M.; Owens, Janel E.; Liu, Bitao; Müller, Hans-Georg; Medrano, Juan F.; Fadel, James G.; Moshfegh, Alanna J.; Baer, David J.; Novotny, Janet A.

    2012-01-01

    Using linear regression models, we studied the main and 2-way interaction effects of the predictor variables gender, age, BMI, and 64 folate/vitamin B-12/homocysteine (Hcy)/lipid/cholesterol-related single nucleotide polymorphisms (SNP) on log-transformed plasma Hcy normalized by RBC folate measurements (nHcy) in 373 healthy Caucasian adults (50% women). Variable selection was conducted by stepwise Akaike information criterion or least angle regression and both methods led to the same final model. Significant predictors (where P values were adjusted for false discovery rate) included type of blood sample [whole blood (WB) vs. plasma-depleted WB; P < 0.001] used for folate analysis, gender (P < 0.001), and SNP in genes SPTLC1 (rs11790991; P = 0.040), CRBP2 (rs2118981; P < 0.001), BHMT (rs3733890; P = 0.019), and CETP (rs5882; P = 0.017). Significant 2-way interaction effects included gender × MTHFR (rs1801131; P = 0.012), gender × CRBP2 (rs2118981; P = 0.011), and gender × SCARB1 (rs83882; P = 0.003). The relation of nHcy concentrations with the significant SNP (SPTLC1, BHMT, CETP, CRBP2, MTHFR, and SCARB1) is of interest, especially because we surveyed the main and interaction effects in healthy adults, but it is an important area for future study. As discussed, understanding Hcy and genetic regulation is important, because Hcy may be related to inflammation, obesity, cardiovascular disease, and diabetes mellitus. We conclude that gender and SNP significantly affect nHcy. PMID:22833659

  15. Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.

    PubMed

    Clifford, Andrew J; Chen, Kehui; McWade, Laura; Rincon, Gonzalo; Kim, Seung-Hyun; Holstege, Dirk M; Owens, Janel E; Liu, Bitao; Müller, Hans-Georg; Medrano, Juan F; Fadel, James G; Moshfegh, Alanna J; Baer, David J; Novotny, Janet A

    2012-09-01

    Using linear regression models, we studied the main and 2-way interaction effects of the predictor variables gender, age, BMI, and 64 folate/vitamin B-12/homocysteine (Hcy)/lipid/cholesterol-related single nucleotide polymorphisms (SNP) on log-transformed plasma Hcy normalized by RBC folate measurements (nHcy) in 373 healthy Caucasian adults (50% women). Variable selection was conducted by stepwise Akaike information criterion or least angle regression and both methods led to the same final model. Significant predictors (where P values were adjusted for false discovery rate) included type of blood sample [whole blood (WB) vs. plasma-depleted WB; P < 0.001] used for folate analysis, gender (P < 0.001), and SNP in genes SPTLC1 (rs11790991; P = 0.040), CRBP2 (rs2118981; P < 0.001), BHMT (rs3733890; P = 0.019), and CETP (rs5882; P = 0.017). Significant 2-way interaction effects included gender × MTHFR (rs1801131; P = 0.012), gender × CRBP2 (rs2118981; P = 0.011), and gender × SCARB1 (rs83882; P = 0.003). The relation of nHcy concentrations with the significant SNP (SPTLC1, BHMT, CETP, CRBP2, MTHFR, and SCARB1) is of interest, especially because we surveyed the main and interaction effects in healthy adults, but it is an important area for future study. As discussed, understanding Hcy and genetic regulation is important, because Hcy may be related to inflammation, obesity, cardiovascular disease, and diabetes mellitus. We conclude that gender and SNP significantly affect nHcy. PMID:22833659

  16. Against the Odds Exhibition Opens

    MedlinePlus

    ... LA and Vox Populi organizations. Photo courtesy of Bill Branson At the exhibition, HIV and AIDS were topics addressed by Dr. Victoria Cargill (right), Director of Clinical Studies and Director of Minority ...

  17. MarsQuest: A National Traveling Exhibition

    NASA Astrophysics Data System (ADS)

    Lee, S. W.; Dusenbery, P. B.

    1998-09-01

    With the successful landing of Mars Pathfinder and the arrival of Mars Global Surveyor, a new decade of Mars exploration has commenced. MarsQuest, a 5000 square foot traveling exhibition, is being developed to further bring the excitement and discoveries of this "Decade of Mars Exploration" to the public. MarsQuest is partially funded by the Informal Science Education Program of the National Science Foundation and NASA's Office of Space Science. The Space Science Institute (SSI) in Boulder, CO, is leading the project. Scientific and educational advisors from many different universities and government laboratories, most of whom are directly involved in the active and planned Mars missions, will ensure the scientific accuracy, timeliness, and relevance of the key concepts presented in the exhibition and accompanying programs. The traveling exhibit is the primary element of the MarsQuest project. The exhibition experience, carefully keyed to current events in Mars exploration, will transport visitors to the surface of the Red Planet via large murals, dioramas, and numerous interactive displays. There they will have the opportunity to share in the spirit and thrill of exploration, and come to appreciate the similarities and differences between Earth and Mars. A planetarium show, geared to the goals of the MarsQuest project, will be an important sensory addition to the traveling exhibit. The planetarium/star-theater venue presents a unique environment where audience members can literally be surrounded by Mars images. Education and outreach programs comprise the remainder of the MarsQuest project. The goal of these is to make scientific concepts and scientific and engineering processes understandable to students via Mars-inspired curricula. MarsQuest will open in late-1999, traveling to about nine sites throughout the United States and reaching an estimated two to three million children and adults during its planned three-year tour. Mars - coming soon to a museum near

  18. Greenhouse Earth: A Traveling Exhibition

    SciTech Connect

    Booth, W.H.; Caesar, S.

    1992-09-01

    The Franklin Institute Science Museum provided an exhibit entitled the Greenhouse Earth: A Traveling Exhibition. This 3500 square-foot exhibit on global climate change was developed in collaboration with the Association of Science-Technology Centers. The exhibit opened at The Franklin Institute on February 14, 1992, welcoming 291,000 visitors over its three-month stay. During its three-year tour, Greenhouse Earth will travel to ten US cities, reaching two million visitors. Greenhouse Earth aims to deepen public understanding of the scientific issues of global warming and the conservation measures that can be taken to slow its effects. The exhibit features hands-on exhibitry, interactive computer programs and videos, a theater production, a demonstration cart,'' guided tours, and lectures. supplemental educational programs at the Institute included a teachers preview, a symposium on climate change, and a satellite field trip.'' The development of Greenhouse Earth included front-end and formative evaluation procedures. Evaluation includes interviews with visitors, prototypes, and summative surveys for participating museums. During its stay in Philadelphia, Greenhouse Earth was covered by the local and national press, with reviews in print and broadcast media. Greenhouse Earth is the first large-scale museum exhibit to address global climate change.

  19. Communicating Complex Sciences by Means of Exhibitions

    NASA Astrophysics Data System (ADS)

    Schneider, S.

    2011-12-01

    Earth Sciences will have to take over the leading role in global sustainable policy and in discussions about climate change. Efforts to raise attention within the politically responsible communities as well as in the public are getting more and more support by executive and advisory boards all over the world. But how can you successfully communicate complex sciences? For example, to start communication about climate change, the first step is to encourage people to be concerned about climate change. After that, one has to start thinking about how to present data and how to include the presented data into an unprejudiced context. Therefore, the communication toolbox offers various methods to reach diverse audiences. The R&D programme GEOTECHNOLOGIEN conducts roving exhibitions as one of its most successful communication tools. With roving exhibitions GEOTECHNOLOGIEN is able to get in touch with different audiences at once. The main purpose and theme of these exhibitions is to convey the everyday means of climate change to the visitors. It is within the responsibility of science to communicate the effects of a phenomenon like climate change as well as the impact of research results to the everyday life of people. Currently, a GEOTECHNOLOGIEN roving exhibition on remote sensing with satellites deals with various issues of environmental research, including a chapter on climate change. By following the 3M-concept (Meaning - Memorable - Moving), exhibitions allow to connect the visitors daily environment and personal experiences with the presented issues and objects. Therefore, hands-on exhibits, exciting multimedia effects and high-tech artefacts have to be combined with interpretive text elements to highlight the daily significance of the scientific topics and the exhibition theme respectively. To create such an exhibition, strong conceptual planning has to be conducted. This includes the specification of stern financial as well as time wise milestones. In addition

  20. Neural Correlates of Letter Reversal in Children and Adults

    PubMed Central

    Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D. E.

    2014-01-01

    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging) and the electrophysiological correlates (via event-related potentials or ERPs) of this phenomenon in children, ages 5–12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA) in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing. PMID:24859328

  1. Considering High-Tech Exhibits?

    ERIC Educational Resources Information Center

    Routman, Emily

    1994-01-01

    Discusses a variety of high-tech exhibit media used in The Living World, an educational facility operated by The Saint Louis Zoo. Considers the strengths and weaknesses of holograms, video, animatronics, video-equipped microscopes, and computer interactives. Computer interactives are treated with special attention. (LZ)

  2. Balamuthia mandrillaris exhibits metalloprotease activities.

    PubMed

    Matin, Abdul; Stins, Monique; Kim, Kwang Sik; Khan, Naveed Ahmed

    2006-06-01

    Balamuthia mandrillaris is a recently identified protozoan pathogen that can cause fatal granulomatous encephalitis. However, the pathogenesis and pathophysiology of B. mandrillaris encephalitis remain unclear. Because proteases may play a role in the central nervous system (CNS) pathology, we used spectrophotometric, cytopathic and zymographic assays to assess protease activities of B. mandrillaris. Using two clinical isolates of B. mandrillaris (from human and baboon), we observed that B. mandrillaris exhibits protease activities. Zymographic assays revealed major protease bands of approximate molecular weights in the region of 40-50 kDa on sodium dodecyl sulfate-polyacrylamide gels using gelatin as substrate. The protease bands were inhibited with 1,10-phenanthroline, suggesting metallo-type proteases. The proteolytic activities were observed over a pH range of 5-11 with maximum activity at neutral pH and at 42 degrees C. Balamuthia mandrillaris proteases exhibit properties to degrade extracellular matrix (ECM), which provide structural and functional support to the brain tissue. This is shown by degradation of collagen I and III (major components of collagenous ECM), elastin (elastic fibrils of ECM), plasminogen (involved in proteolytic degradation of ECM), as well as other substrates such as casein and gelatin but not haemoglobin. However, these proteases exhibited a minimal role in B. mandrillaris-mediated host cell death in vitro using human brain microvascular endothelial cells (HBMECs). This was shown using broad-spectrum matrix metalloprotease inhibitors, GM 6001 and GM 1489, which had no effect on B. mandrillaris-mediated HBMEC cytotoxicity. This is the first demonstration that B. mandrillaris exhibits metalloproteases, which may play important role(s) in the ECM degradation and thus in CNS pathology. PMID:16706791

  3. Life satisfaction in young adults 10 or more years after hematopoietic stem cell transplantation for childhood malignant and nonmalignant diseases does not show significant impairment compared with healthy controls: a case-matched study.

    PubMed

    Uderzo, Cornelio; Corti, Paola; Pappalettera, Marco; Baldini, Valentina; Lucchini, Giovanna; Meani, Dario; Rovelli, Attilio

    2012-11-01

    Patients undergoing hematopoietic stem cell transplantation (HSCT) may experience physical and psychological deterioration that impairs their life satisfaction (LS). This study focused on LS in long-term survivors at 10 or more years after HSCT. Fifty-five patients (39 males, median age 25 years) undergoing allogeneic HSCT for childhood malignant (n = 52) or nonmalignant diseases (n = 3) were enrolled. A control group of 98 young adults (59 males, median age 24 years) was considered. A questionnaire with a modified Satisfaction Life Domain Scale was administered. We assessed such domains as education, employment, leisure time, social relationships, and perception of physical status with a 30-item questionnaire. To investigate the association between the domains and the probability of diminished LS, we performed a logistical procedure using the maximum likelihood method. Predictive factors of LS were adjusted for sociodemographic variables. In the multivariate analysis, the participant's level of LS was not significantly correlated with sociodemographic factors or with HSCT status. The same analysis showed a slight trend in favor of the control group (P = .06) for body perception. Our data suggest that the patients who undergo HSCT in childhood have no significant difference in long-term LS compared with healthy controls.

  4. Crows spontaneously exhibit analogical reasoning.

    PubMed

    Smirnova, Anna; Zorina, Zoya; Obozova, Tanya; Wasserman, Edward

    2015-01-19

    Analogical reasoning is vital to advanced cognition and behavioral adaptation. Many theorists deem analogical thinking to be uniquely human and to be foundational to categorization, creative problem solving, and scientific discovery. Comparative psychologists have long been interested in the species generality of analogical reasoning, but they initially found it difficult to obtain empirical support for such thinking in nonhuman animals (for pioneering efforts, see [2, 3]). Researchers have since mustered considerable evidence and argument that relational matching-to-sample (RMTS) effectively captures the essence of analogy, in which the relevant logical arguments are presented visually. In RMTS, choice of test pair BB would be correct if the sample pair were AA, whereas choice of test pair EF would be correct if the sample pair were CD. Critically, no items in the correct test pair physically match items in the sample pair, thus demanding that only relational sameness or differentness is available to support accurate choice responding. Initial evidence suggested that only humans and apes can successfully learn RMTS with pairs of sample and test items; however, monkeys have subsequently done so. Here, we report that crows too exhibit relational matching behavior. Even more importantly, crows spontaneously display relational responding without ever having been trained on RMTS; they had only been trained on identity matching-to-sample (IMTS). Such robust and uninstructed relational matching behavior represents the most convincing evidence yet of analogical reasoning in a nonprimate species, as apes alone have spontaneously exhibited RMTS behavior after only IMTS training.

  5. Collaborative virtual environments art exhibition

    NASA Astrophysics Data System (ADS)

    Dolinsky, Margaret; Anstey, Josephine; Pape, Dave E.; Aguilera, Julieta C.; Kostis, Helen-Nicole; Tsoupikova, Daria

    2005-03-01

    This panel presentation will exhibit artwork developed in CAVEs and discuss how art methodologies enhance the science of VR through collaboration, interaction and aesthetics. Artists and scientists work alongside one another to expand scientific research and artistic expression and are motivated by exhibiting collaborative virtual environments. Looking towards the arts, such as painting and sculpture, computer graphics captures a visual tradition. Virtual reality expands this tradition to not only what we face, but to what surrounds us and even what responds to our body and its gestures. Art making that once was isolated to the static frame and an optimal point of view is now out and about, in fully immersive mode within CAVEs. Art knowledge is a guide to how the aesthetics of 2D and 3D worlds affect, transform, and influence the social, intellectual and physical condition of the human body through attention to psychology, spiritual thinking, education, and cognition. The psychological interacts with the physical in the virtual in such a way that each facilitates, enhances and extends the other, culminating in a "go together" world. Attention to sharing art experience across high-speed networks introduces a dimension of liveliness and aliveness when we "become virtual" in real time with others.

  6. Crows spontaneously exhibit analogical reasoning.

    PubMed

    Smirnova, Anna; Zorina, Zoya; Obozova, Tanya; Wasserman, Edward

    2015-01-19

    Analogical reasoning is vital to advanced cognition and behavioral adaptation. Many theorists deem analogical thinking to be uniquely human and to be foundational to categorization, creative problem solving, and scientific discovery. Comparative psychologists have long been interested in the species generality of analogical reasoning, but they initially found it difficult to obtain empirical support for such thinking in nonhuman animals (for pioneering efforts, see [2, 3]). Researchers have since mustered considerable evidence and argument that relational matching-to-sample (RMTS) effectively captures the essence of analogy, in which the relevant logical arguments are presented visually. In RMTS, choice of test pair BB would be correct if the sample pair were AA, whereas choice of test pair EF would be correct if the sample pair were CD. Critically, no items in the correct test pair physically match items in the sample pair, thus demanding that only relational sameness or differentness is available to support accurate choice responding. Initial evidence suggested that only humans and apes can successfully learn RMTS with pairs of sample and test items; however, monkeys have subsequently done so. Here, we report that crows too exhibit relational matching behavior. Even more importantly, crows spontaneously display relational responding without ever having been trained on RMTS; they had only been trained on identity matching-to-sample (IMTS). Such robust and uninstructed relational matching behavior represents the most convincing evidence yet of analogical reasoning in a nonprimate species, as apes alone have spontaneously exhibited RMTS behavior after only IMTS training. PMID:25532894

  7. "I Remember the Whole Board Being Full of Different Calculations and Trying to Make Some Sense of It." The Influence of Significant Moments in Adult Numeracy Teachers' Own Learning Experiences on Their Teaching Practice

    ERIC Educational Resources Information Center

    Brooks, Carolyn

    2014-01-01

    In researching how adult numeracy teachers actively motivate and enable learners to apply the numeracy skills they learn to their own real life practices, a case study of two adult numeracy teachers and their learner groups was undertaken. This paper compares the teachers' contrasting personal experiences of mathematics learning to consider how…

  8. Children do not exhibit ambiguity aversion despite intact familiarity bias

    PubMed Central

    Li, Rosa; Brannon, Elizabeth M.; Huettel, Scott A.

    2015-01-01

    The phenomenon of ambiguity aversion, in which risky gambles with known probabilities are preferred over ambiguous gambles with unknown probabilities, has been thoroughly documented in adults but never measured in children. Here, we use two distinct tasks to investigate ambiguity preferences of children (8- to 9-year-olds) and a comparison group of adults (19- to 27-year-olds). Across three separate measures, we found evidence for significant ambiguity aversion in adults but not in children and for greater ambiguity aversion in adults compared to children. As ambiguity aversion in adults has been theorized to result from a preference to bet on the known and avoid the unfamiliar, we separately measured familiarity bias and found that children, like adults, are biased towards the familiar. Our findings indicate that ambiguity aversion emerges across the course of development between childhood and adolescence, while a familiarity bias is already present in childhood. PMID:25601848

  9. Bumblebees exhibit the memory spacing effect

    NASA Astrophysics Data System (ADS)

    Toda, Nicholas R. T.; Song, Jeremy; Nieh, James C.

    2009-10-01

    Associative learning is key to how bees recognize and return to rewarding floral resources. It thus plays a major role in pollinator floral constancy and plant gene flow. Honeybees are the primary model for pollinator associative learning, but bumblebees play an important ecological role in a wider range of habitats, and their associative learning abilities are less well understood. We assayed learning with the proboscis extension reflex (PER), using a novel method for restraining bees (capsules) designed to improve bumblebee learning. We present the first results demonstrating that bumblebees exhibit the memory spacing effect. They improve their associative learning of odor and nectar reward by exhibiting increased memory acquisition, a component of long-term memory formation, when the time interval between rewarding trials is increased. Bombus impatiens forager memory acquisition (average discrimination index values) improved by 129% and 65% at inter-trial intervals (ITI) of 5 and 3 min, respectively, as compared to an ITI of 1 min. Memory acquisition rate also increased with increasing ITI. Encapsulation significantly increases olfactory memory acquisition. Ten times more foragers exhibited at least one PER response during training in capsules as compared to traditional PER harnesses. Thus, a novel conditioning assay, encapsulation, enabled us to improve bumblebee-learning acquisition and demonstrate that spaced learning results in better memory consolidation. Such spaced learning likely plays a role in forming long-term memories of rewarding floral resources.

  10. 17 CFR 232.102 - Exhibits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Regulation S-T (17 CFR 232.311(b)). (b) Amendments to all exhibits shall be filed in electronic format... designation “CE” (confirming electronic) should be placed next to the listed exhibit in the exhibit index....

  11. Adult Books for Young Adults.

    ERIC Educational Resources Information Center

    Carter, Betty

    1997-01-01

    Considers the differences between young adult and adult books and maintains that teachers must be familiar with young adults' tastes for both. Suggests that traffic between these publishing divisions is a two-way street, with young adults reading adult books and adults reading young adult books. (TB)

  12. Age-Related Gene Expression Differences in Monocytes from Human Neonates, Young Adults, and Older Adults

    PubMed Central

    Tong, Ann-Jay; Kollmann, Tobias R.; Smale, Stephen T.

    2015-01-01

    A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opportunity to obtain an unbiased, comprehensive, and quantitative view of gene expression differences in defined cell types from different age groups. An examination of ex vivo human monocyte responses to lipopolysaccharide stimulation or Listeria monocytogenes infection by RNA-seq revealed extensive similarities between neonates, young adults, and older adults, with an unexpectedly small number of genes exhibiting statistically significant age-dependent differences. By examining the differentially induced genes in the context of transcription factor binding motifs and RNA-seq data sets from mutant mouse strains, a previously described deficiency in interferon response factor-3 activity could be implicated in most of the differences between newborns and young adults. Contrary to these observations, older adults exhibited elevated expression of inflammatory genes at baseline, yet the responses following stimulation correlated more closely with those observed in younger adults. Notably, major differences in the expression of constitutively expressed genes were not observed, suggesting that the age-related differences are driven by environmental influences rather than cell-autonomous differences in monocyte development. PMID:26147648

  13. Exhibits Enhanced by Stand-Alone Computers.

    ERIC Educational Resources Information Center

    Van Rennes, Eve C.

    Both the development and evaluation of one of a set of computer programs designed for use by visitors as adjuncts to museum exhibits are described. Museum displays used were (1) a static, behind-glass exhibit on evolution; (2) a hands-on primitive stone age tools exhibit; and (3) a Foucault pendulum. A computer placed next to each exhibit served…

  14. A Critical Appraisal of State Level Science Exhibition

    ERIC Educational Resources Information Center

    Nath, Baiju K.

    2007-01-01

    Science exhibitions are really great opportunities to students as well as teachers to disseminate knowledge that they have, and to experience a variety of new inventions and innovations that also need wide dissemination. The great significance of exhibition is that it fosters acquisition of different process skills leading to the development of…

  15. Modelling the Future: Exhibitions and the Materiality of Education

    ERIC Educational Resources Information Center

    Lawn, Martin, Ed.

    2009-01-01

    The role of World Exhibitions in the 19th and early 20th centuries was to confirm a relation between the nation state and modernity. As a display about industries, inventions and identities, the Exhibition, in a sense, put entire nations into an elevated, viewable space. It is a significant element in modernity as comparisons can be made, progress…

  16. Good News? Codling Moth Exhibits Negative Cross Resistance Between Guthion and Rimon

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The responses of adult codling moth from several field-collected populations and a laboratory-reared colony to residues of Rimon were evaluated in plastic cup adult bioassays. Both fecundity and successful egg hatch varied among populations. Populations of codling moth that exhibited the highest LC5...

  17. Adult Cancers in Adolescents and Young Adults.

    PubMed

    Laurence, Valérie; Marples, Maria; Stark, Daniel P

    2016-01-01

    The pattern of cancer seen in young people changes with increasing age, transitioning from childhood- to adult-type cancer in adolescence and the third decade. The risk factors, presentation and biology of cancer in young adults differ from those in the older adult population. Factors of particular significance in adolescents and young adults (AYAs) include genetic predisposition to adult-type cancer, diagnostic uncertainty, long-term morbidity and considerations of fertility. New systemic therapies are being introduced that can prolong life and even increase the chance of cure, but the impact on AYAs is uncertain, as these patients are often under-represented in clinical trials. Here, we discuss the management of AYAs with 3 of the most common cancers affecting adults, when they emerge in the AYA populations, and therefore are currently met by medical oncologists - breast cancer, colorectal cancer and melanoma. PMID:27595357

  18. Supercomputing meets seismology in earthquake exhibit

    SciTech Connect

    Blackwell, Matt; Rodger, Arthur; Kennedy, Tom

    2013-10-03

    When the California Academy of Sciences created the "Earthquake: Evidence of a Restless Planet" exhibit, they called on Lawrence Livermore to help combine seismic research with the latest data-driven visualization techniques. The outcome is a series of striking visualizations of earthquakes, tsunamis and tectonic plate evolution. Seismic-wave research is a core competency at Livermore. While most often associated with earthquakes, the research has many other applications of national interest, such as nuclear explosion monitoring, explosion forensics, energy exploration, and seismic acoustics. For the Academy effort, Livermore researchers simulated the San Andreas and Hayward fault events at high resolutions. Such calculations require significant computational resources. To simulate the 1906 earthquake, for instance, visualizing 125 seconds of ground motion required over 1 billion grid points, 10,000 time steps, and 7.5 hours of processor time on 2,048 cores of Livermore's Sierra machine.

  19. Supercomputing meets seismology in earthquake exhibit

    ScienceCinema

    Blackwell, Matt; Rodger, Arthur; Kennedy, Tom

    2016-07-12

    When the California Academy of Sciences created the "Earthquake: Evidence of a Restless Planet" exhibit, they called on Lawrence Livermore to help combine seismic research with the latest data-driven visualization techniques. The outcome is a series of striking visualizations of earthquakes, tsunamis and tectonic plate evolution. Seismic-wave research is a core competency at Livermore. While most often associated with earthquakes, the research has many other applications of national interest, such as nuclear explosion monitoring, explosion forensics, energy exploration, and seismic acoustics. For the Academy effort, Livermore researchers simulated the San Andreas and Hayward fault events at high resolutions. Such calculations require significant computational resources. To simulate the 1906 earthquake, for instance, visualizing 125 seconds of ground motion required over 1 billion grid points, 10,000 time steps, and 7.5 hours of processor time on 2,048 cores of Livermore's Sierra machine.

  20. [Parasitologic significance of the alteration of the causative Anisakidae worm and of the Pseudoterranova decipiens female immature adult worm, casting off the cuticles, and excreted from human in Kanazawa City].

    PubMed

    Ishikura, H; Kikuchi, K; Akao, N; Doutei, M; Yagi, K; Takahashi, S; Sato, N

    1995-09-01

    We have been studying Anisakidae larvae, their intermediate hosts and their final hosts in the northern Japan Sea area. These larvae cause anisakidosis. According to the investigation, the recent burst of pseudoterranovosis in this area can be attributed to the increased presence of sea lions, which proliferate in the Arctic region, then migrate to the northern Japan Sea and eat the intermediate host fish. In a stomach of a male sea lion that was captured in February 1995, we found more than 4,500 Pseudoterranova decipiens. Although there is no known circumstance in which a human would consume an adult worm of Anisakis nematode, an astonishing case of this was found in Kanazawa; a female young adult Pseudoterranova decipiens undergoing the final metamorphosis was emitted from a patient. This indicates that the Anisakis larva can mature into the adult worm in humans. It is postulated that the Pseudoterranova decipiens larva is in the process of adapting to use humans as the final host. PMID:8543275