Science.gov

Sample records for adults exhibited significantly

  1. 76 FR 61472 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Game of Kings: Medieval Ivory... Kings: Medieval Ivory Chessmen from the Isle of Lewis,'' imported from abroad for temporary exhibition..., Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: September 27, 2011. J. Adam Ereli,...

  2. 75 FR 6079 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Compass and Rule: Architecture as...: Architecture as Mathematical Practice in England, 1500-1750,'' imported from abroad for temporary...

  3. 76 FR 68808 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... Exhibition Determinations: ``Transition to Christianity: Art of Late Antiquity, 3rd-7th Century AD'' SUMMARY... objects to be included in the exhibition ``Transition to Christianity: Art of Late Antiquity, 3rd-7th Century AD,'' imported from abroad for temporary exhibition within the United States, are of...

  4. 78 FR 55134 - Culturally Significant Object Imported for Exhibition Determinations: “Iran Modern”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Iran Modern'' ACTION: Notice..., number 153) of determinations made by the Department of State pertaining to the exhibit ``Iran Modern... in the exhibition ``Iran Modern,'' imported from abroad for temporary exhibition within the...

  5. Praziquantel derivatives exhibit activity against both juvenile and adult Schistosoma japonicum.

    PubMed

    Duan, Wen-wen; Qiu, Si-jie; Zhao, Yue; Sun, Huan; Qiao, Chunhua; Xia, Chao-ming

    2012-02-15

    A praziquantel analog 10-hydroxy praziquantel and eight praziquantel/peroxide conjugates were synthesized. The biological activity of these compounds was evaluated against juvenile and adult stages of Schistosoma japonicum. Unlike praziquantel, 10-hydroxy praziquantel exhibits activity against both juvenile and adult Schistosoma japonicumin. All hybrid compounds displayed modest to significant worm killing activity. The present study has important significance for the development of hybrid antischistosomal drugs.

  6. 68 FR 16852 - Culturally Significant Objects Imported for Exhibition Determinations: “Max Beckmann”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-04-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Max Beckmann'' AGENCY: Department of... exhibition, ``Max Beckmann,'' imported from abroad for temporary exhibition within the United States, are...

  7. 75 FR 28095 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso Looks at Degas”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso Looks at Degas'' SUMMARY... included in the exhibition ``Picasso Looks at Degas,'' imported from abroad for temporary exhibition...

  8. 75 FR 32980 - Culturally Significant Objects Imported for Exhibition Determinations: “Ringo Starr's Snare Drum”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ringo Starr's Snare Drum'' SUMMARY... included in the exhibit ``Ringo Starr's Snare Drum,'' imported from abroad for temporary exhibition...

  9. 78 FR 45285 - Culturally Significant Objects Imported for Exhibition Determinations: “Egypt's Mysterious Book...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Egypt's Mysterious Book of the..., 2003), I hereby determine that the objects to be included in the exhibition ``Egypt's Mysterious Book... custodians. I also determine that the exhibition or display of the exhibit objects at The Walters Art...

  10. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Holocaust'' SUMMARY: Notice is... included in the exhibition ``The Holocaust,'' imported from abroad for temporary exhibition within the... objects in the permanent exhibit of the U.S. Holocaust Memorial Museum, Washington, DC, from on or...

  11. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “Birth of Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Birth of Impressionism: Masterpieces... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Birth...

  12. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Kurt Schwitters: Color...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Kurt Schwitters: Color and Collage... Schwitters: Color and Collage,'' imported from abroad for temporary exhibition within the United States,...

  13. 78 FR 4972 - Culturally Significant Objects Imported for Exhibition Determinations: “Chagall: Beyond Color”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chagall: Beyond Color'' SUMMARY... objects to be included in the exhibition ``Chagall: Beyond Color,'' imported from abroad for...

  14. 77 FR 48198 - Culturally Significant Objects Imported for Exhibition Determinations: “Faking It: Manipulated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Faking It: Manipulated Photography..., 2003), I hereby determine that the objects to be included in the exhibition ``Faking It:...

  15. 78 FR 51802 - Culturally Significant Objects Imported for Exhibition Determinations: “Robert Motherwell: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Robert Motherwell: The Early..., 2003, I hereby determine that the objects to be included in the exhibition ``Robert Motherwell:...

  16. 76 FR 1660 - Culturally Significant Objects Imported for Exhibition Determinations: “Art in Cameroon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Art in Cameroon: Sculptural... ``Art in Cameroon: Sculptural Dialogues,'' imported from abroad for temporary exhibition within...

  17. 78 FR 17744 - Culturally Significant Objects Imported for Exhibition Determinations: “Maya: Hidden Worlds...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Maya: Hidden Worlds Revealed... determine that the objects to be included in the exhibition ``Maya: Hidden Worlds Revealed,'' imported...

  18. 78 FR 28274 - Culturally Significant Objects Imported for Exhibition Determinations: “Medieval Treasures from...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Medieval Treasures from Hildesheim... determine that the objects to be included in the exhibition ``Medieval Treasures from Hildesheim,''...

  19. 78 FR 68134 - Culturally Significant Objects Imported for Exhibition Determinations: “Renaissance to Goya...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Renaissance to Goya: Prints and... ``Renaissance to Goya: Prints and Drawings from Spain,'' imported from abroad for temporary exhibition...

  20. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Federico Barocci...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Federico Barocci: Renaissance Master... determine that the objects to be included in the exhibition ``Federico Barocci: Renaissance...

  1. 78 FR 48925 - Culturally Significant Object Imported for Exhibition Determinations: “Violence and Virtue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Violence and Virtue: Artemisia... April 15, 2003), I hereby determine that the object to be included in the exhibition ``Violence...

  2. 78 FR 61981 - Culturally Significant Objects Imported for Exhibition Determinations: “Anders Zorn: Sweden's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Anders Zorn: Sweden's Master Painter... determine that the objects to be included in the exhibition ``Anders Zorn: Sweden's Master...

  3. 76 FR 38452 - Culturally Significant Object Imported for Exhibition Determinations: “King Amenemhet II”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``King Amenemhet II'' SUMMARY: Notice..., I hereby determine that the object to be included in the exhibition ``King Amenemhet II,''...

  4. 75 FR 62916 - Culturally Significant Objects Imported for Exhibition Determinations: “India's Fabled City: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``India's Fabled City: The Art of... ``India's Fabled City: The Art of Courtly Lucknow,'' imported from abroad for temporary exhibition...

  5. 75 FR 25031 - Culturally Significant Objects Imported for Exhibition Determinations: “Tiffany: Color and Light”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tiffany: Color and Light'' SUMMARY... included in the exhibition ``Tiffany: Color and Light,'' imported from abroad for temporary...

  6. 77 FR 61045 - Culturally Significant Objects Imported for Exhibition Determinations: “China's Terracotta...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``China's Terracotta Warriors: The... Terracotta Warriors: The First Emperor's Legacy,'' imported from abroad for temporary exhibition within...

  7. 78 FR 79057 - Culturally Significant Objects Imported for Exhibition Determinations: “Gauguin: Metamorphoses”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gauguin: Metamorphoses'' SUMMARY..., I hereby determine that the objects to be included in the exhibition, ``Gauguin:...

  8. 70 FR 43928 - Culturally Significant Objects Imported for Exhibition Determinations: “Max Liebermann: From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2005-07-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Max Liebermann: From Realism to... , I hereby determine that the objects to be included in the exhibition, ``Max Liebermann: From...

  9. 68 FR 23172 - Culturally Significant Objects Imported for Exhibition Determinations: “Max Beckmann”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-04-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Max Beckmann'' AGENCY: Department of... , as amended, I hereby determine that one additional object to be included in the exhibition,...

  10. 76 FR 77582 - Culturally Significant Objects Imported for Exhibition Determinations: “Cindy Sherman”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Cindy Sherman'' SUMMARY: Notice is... objects to be included in the exhibition ``Cindy Sherman,'' imported from abroad for temporary...

  11. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso's Drawings, 1890...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso's Drawings, 1890-1921..., 2003), I hereby determine that the objects to be included in the exhibition ``Picasso's Drawings,...

  12. 76 FR 53524 - Culturally Significant Objects Imported for Exhibition Determinations: “Once Upon Many Times...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Once Upon Many Times: Legends and... Times: Legends and Myths in Himalayan Art,'' imported from abroad for temporary exhibition within...

  13. 78 FR 15802 - Culturally Significant Objects Imported for Exhibition Determinations: “Hans Richter: Encounters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Hans Richter: Encounters'' SUMMARY... objects to be included in the exhibition ``Hans Richter: Encounters,'' imported from abroad for...

  14. 77 FR 65245 - Culturally Significant Objects Imported for Exhibition Determinations: “Portrait of Spain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Portrait of Spain: Masterpieces From..., 2003), I hereby determine that the objects to be included in the exhibition ``Portrait of...

  15. 76 FR 4986 - Culturally Significant Object Imported for Exhibition Determinations: “Gentile Bellini: Portrait...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Gentile Bellini: Portrait of Caterina... the exhibition ``Gentile Bellini: Portrait of Caterina Cornaro, Queen of Cyprus,'' imported...

  16. 77 FR 8943 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt's Self-Portrait”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rembrandt's Self-Portrait'' SUMMARY... object to be included in the exhibition ``Rembrandt's Self-Portrait,'' imported from abroad for...

  17. 78 FR 5555 - Culturally Significant Objects Imported for Exhibition Determinations: “SHANGAA, Art of Tanzania”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``SHANGAA, Art of Tanzania'' SUMMARY... objects to be included in the exhibition ``SHANGAA, Art of Tanzania,'' imported from abroad for...

  18. 75 FR 28848 - Culturally Significant Objects Imported for Exhibition Determinations: “The Original Copy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Original Copy: Photography of... hereby determine that the objects to be included in the exhibition ``The Original Copy: Photography...

  19. 77 FR 50542 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2012...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2012: Michele Abeles... objects to be included in the exhibition ``New Photography 2012: Michele Abeles, Birdhead (Ji Weiyu...

  20. 76 FR 53993 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2011: Zhang Dali... objects to be included in the exhibition ``New Photography 2011: Zhang Dali, Moyra Davey, George...

  1. 78 FR 40544 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2013...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2013: Adam Broomberg..., 2003), I hereby determine that the objects to be included in the exhibition ``New Photography...

  2. 77 FR 2340 - Culturally Significant Objects Imported for Exhibition Determinations: “Snapshot: Painters and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Snapshot: Painters and Photography... Photography, Bonnard to Vuillard'' imported from abroad for temporary exhibition within the United States,...

  3. 76 FR 59182 - Culturally Significant Objects Imported for Exhibition Determinations: “Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Impressionism: Masterworks on Paper... determine that the objects to be included in the exhibition ``Impressionism: Masterworks on Paper''...

  4. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Poetry in Clay: Korean...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Poetry in Clay: Korean Buncheong... objects to be included in the exhibition ``Poetry in Clay: Korean Buncheong Ceramics from the...

  5. 77 FR 34121 - Culturally Significant Objects Imported for Exhibition Determinations: “Lucian Freud: Portraits”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Lucian Freud: Portraits'' SUMMARY... object to be included in the exhibition ``Lucian Freud: Portraits,'' imported from abroad by The...

  6. 75 FR 8425 - Culturally Significant Objects Imported for Exhibition Determinations: “Masterpieces of European...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Masterpieces of European Painting... European Painting from Dulwich Picture Gallery,'' imported from abroad for temporary exhibition within...

  7. 76 FR 65558 - Culturally Significant Objects Imported for Exhibition Determinations: “Masterpieces of Landscape...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Masterpieces of Landscape Painting... Landscape Painting from the Forbidden City'' imported from abroad for temporary exhibition within the...

  8. 78 FR 79058 - Culturally Significant Objects Imported for Exhibition Determinations: “Chinese Paintings from...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chinese Paintings from Japanese..., 2003), I hereby determine that the objects to be included in the exhibition ``Chinese Paintings...

  9. 78 FR 23623 - Culturally Significant Objects Imported for Exhibition Determinations: “American Encounters...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``American Encounters: Genre Painting...: Genre Painting and Everyday Life,'' imported from abroad for temporary exhibition within the...

  10. 76 FR 20802 - Culturally Significant Object Imported for Exhibition Determinations: “The Capitoline Venus”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``The Capitoline Venus'' SUMMARY..., I hereby determine that the object to be included in the exhibition ``The Capitoline...

  11. 75 FR 53012 - Culturally Significant Object Imported for Exhibition Determinations: “Ivory Mirror Case”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Ivory Mirror Case'' SUMMARY: Notice..., I hereby determine that the object to be included in the exhibition ``Ivory Mirror Case,''...

  12. 78 FR 20372 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' SUMMARY... objects to be included in the exhibition ``Hall of Ancient Egypt,'' imported from abroad for...

  13. 76 FR 5236 - Culturally Significant Objects Imported for Exhibition Determinations: “Upside Down Arctic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Upside Down Arctic Realities... Down Arctic Realities,'' imported from abroad for temporary exhibition within the United States, are...

  14. 75 FR 51518 - Culturally Significant Objects Imported for Exhibition Determinations: “Ballplayers, Gods, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ballplayers, Gods, and Rainmaker... objects to be included in the exhibition ``Ballplayers, Gods, and Rainmaker Kings: Masterpieces...

  15. 76 FR 23642 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 95: Runa Islam”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Projects 95: Runa Islam'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Projects 95: Runa...

  16. 75 FR 66419 - Culturally Significant Objects Imported for Exhibition Determinations: “Object of Devotion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Object of Devotion: Medieval English... objects to be included in the exhibition ``Object of Devotion: Medieval English Alabaster Sculpture...

  17. 77 FR 23318 - Culturally Significant Object Imported for Exhibition Determinations: “African Cosmos: Stellar Arts”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``African Cosmos: Stellar Arts... Cosmos: Stellar Arts,'' imported from abroad for temporary exhibition within the United States, is...

  18. 78 FR 28939 - Culturally Significant Objects Imported for Exhibition Determinations: “Tomoaki Suzuki”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tomoaki Suzuki'' SUMMARY: Notice is... objects to be included in the exhibition ``Tomoaki Suzuki,'' imported from abroad for temporary...

  19. 76 FR 7893 - Culturally Significant Objects Imported for Exhibition Determinations: “Neoclassicism: A Taste...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Neoclassicism: A Taste for the... ``Neoclassicism: A Taste for the Antique,'' imported from abroad for temporary exhibition within the United...

  20. 77 FR 60004 - Culturally Significant Object Imported for Exhibition Determinations: “Wtewael's Adam and Eve”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Wtewael's Adam and Eve'' SUMMARY... object to be included in the exhibition ``Wtewael's Adam and Eve,'' imported from abroad for...

  1. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Charlotte Salomon: Life...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Charlotte Salomon: Life? Or Theatre... Salomon: Life? Or Theatre?'' imported from abroad for temporary exhibition within the United States,...

  2. 78 FR 8682 - Culturally Significant Object Imported for Exhibition Determinations: “Vermeer's Woman in Blue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Vermeer's Woman in Blue Reading a... ``Vermeer's Woman in Blue Reading a Letter,'' imported from abroad for temporary exhibition within...

  3. 78 FR 52997 - Culturally Significant Objects Imported for Exhibition Determinations: “Yoga: the Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Yoga: the Art of Transformation... determine that the objects to be included in the exhibition ``Yoga: the Art of Transformation,''...

  4. 76 FR 58075 - Culturally Significant Object Imported for Exhibition Determinations: “Cervera Bible”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Cervera Bible'' SUMMARY: Notice is... object to be included in the exhibition ``Cervera Bible,'' imported from abroad for temporary...

  5. 76 FR 42158 - Culturally Significant Objects Imported for Exhibition Determinations: “Lyonel Feininger...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Lyonel Feininger: Photographs, 1928...: Photographs: 1928- 1939,'' imported from abroad for temporary exhibition within the United States, are...

  6. 78 FR 1916 - Culturally Significant Objects Imported for Exhibition; Determinations: “Impressionism, Fashion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Impressionism, Fashion, and..., 2003), I hereby determine that the objects to be included in the exhibition ``Impressionism,...

  7. 75 FR 23318 - Culturally Significant Objects Imported for Exhibition Determinations: “John Baldessari: Pure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``John Baldessari: Pure Beauty... that the objects to be included in the exhibition ``John Baldessari: Pure Beauty,'' imported...

  8. 78 FR 48539 - Culturally Significant Objects Imported for Exhibition Determinations: “Iran Modern”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Iran Modern'' SUMMARY: Notice is... objects to be included in the exhibition ``Iran Modern,'' imported from abroad for temporary...

  9. 78 FR 51802 - Culturally Significant Objects Imported for Exhibition Determinations: “Silla: Korea's Golden...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Silla: Korea's Golden Kingdom... determine that the objects to be included in the exhibition ``Silla: Korea's Golden Kingdom,'' imported...

  10. 77 FR 48199 - Culturally Significant Objects Imported for Exhibition Determinations: “Bernini: Sculpting in Clay”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bernini: Sculpting in Clay'' SUMMARY... objects to be included in the exhibition ``Bernini: Sculpting in Clay,'' imported from abroad...

  11. 78 FR 27276 - Culturally Significant Object Imported for Exhibition Determinations: “Goya's Two Hares”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Goya's Two Hares'' SUMMARY: Notice is... object to be included in the exhibition ``Goya's Two Hares,'' imported from abroad for...

  12. 77 FR 61468 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Balthus: Cats and Girls'' SUMMARY... objects to be included in the exhibition ``Balthus: Cats and Girls,'' imported from abroad for...

  13. Significance of Adult Pedestrian Torso Injury

    PubMed Central

    Ivarsson, B. Johan; Henary, Basem; Crandall, Jeff R.; Longhitano, Douglas

    2005-01-01

    The current paper uses data from two trauma registries to evaluate the significance of adult pedestrian torso injury relative to head and lower extremity injuries and to determine the relative importance of injuries to individual torso organs/structures. Analyses are conducted with and without adjusting for striking vehicle body type (car versus LTV). Although the incidence of torso injury is approximately 50% higher in pedestrians struck by LTVs than in those struck by cars, torso injury appears to be as an important contributor to the overall cost of pedestrian morbidity as is lower extremity injury. The most frequently injured torso organs/structures include the rib cage, lung & pleura, and liver. The results indicate a need for an increased focus on the prevention of torso injury in the design of pedestrian safety countermeasures. PMID:16179153

  14. 75 FR 41274 - Culturally Significant Objects Imported for Exhibition Determinations: “The World of Khubilai...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The World of Khubilai Khan: Chinese... Department of State pertaining to the exhibit ``From Xanadu to Dadu: The World of Khubilai Khan.'' The... exhibit name is now titled, ``The World of Khubilai Khan: Chinese Art in the Yuan Dynasty.'' Pursuant...

  15. 77 FR 4858 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... determinations made by ] the Department of State pertaining to the exhibition ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  16. 77 FR 65245 - Culturally Significant Objects Imported for Exhibition Determinations: “Late Roman and Early...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Late Roman and Early Byzantine... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Late Roman and... exhibit objects at the The Art Institute of Chicago in Chicago, Illinois from on or about November...

  17. 78 FR 6398 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso Black and White”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso Black and White'' AGENCY... pertaining to the exhibition ``Picasso Black and White.'' The referenced notice is corrected here to include... ``Picasso Black and White,'' imported from abroad for temporary exhibition within the United States, are...

  18. 76 FR 18292 - Culturally Significant Objects Imported for Exhibition Determinations: “The Steins Collect...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... exhibition or display of all of these exhibit objects at the San Francisco Museum of Modern Art, San... of six of the objects at The Metropolitan Museum of Art, New York, NY, from on or about February 21... Culturally Significant Objects Imported for Exhibition Determinations: ``The Steins Collect: Matisse,...

  19. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Diego Rivera: Murals for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... objects to be included in the exhibition ``Diego Rivera: Murals for The Museum of Modern Art,'' imported... that the exhibition or display of the exhibit objects at The Museum of Modern Art, New York, NY, from...] [FR Doc No: 2011-26518] DEPARTMENT OF STATE [Public Notice: 7646] Culturally Significant...

  20. 78 FR 26682 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' AGENCY... pertaining to the exhibition ``Hall of Ancient Egypt.'' The referenced notice is corrected here to include... of Ancient Egypt,'' imported from abroad for temporary exhibition within the United States, are...

  1. 75 FR 27613 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust (Warsaw...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Holocaust (Warsaw Ghetto... that the documents to be included in the exhibition ``The Holocaust (Warsaw Ghetto),'' imported from... exhibition or display of the documents at the U.S. Holocaust Memorial Museum, Washington, DC, from on...

  2. 77 FR 67725 - Culturally Significant Object Imported for Exhibition Determinations: “Michelangelo's David Apollo”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Michelangelo's David Apollo'' SUMMARY... object to be included in the exhibition ``Michelangelo's David Apollo,'' imported from abroad for... display of the exhibit object at the National Gallery of Art, Washington, DC, from on or about December...

  3. 75 FR 1680 - Culturally Significant Objects Imported for Exhibition Determinations: “Roman Art”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Roman Art'' SUMMARY: Notice is... included in the exhibition ``Roman Art,'' imported from abroad for temporary exhibition within the United... the Metropolitan Museum of Art, New York, NY, from on or about January 2010 until on or about...

  4. 78 FR 59080 - Culturally Significant Objects Imported for Exhibition Determinations: “Delacroix and the Matter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Delacroix and the Matter of Finish... determine that the objects to be included in the exhibition ``Delacroix and the Matter of Finish,''...

  5. 75 FR 39724 - Culturally Significant Objects Imported for Exhibition Determinations: “Arcimboldo (1526-1593...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Arcimboldo (1526-1593): Nature and... hereby determine that the objects to be included in the exhibition ``Arcimboldo (1526-1593): Nature...

  6. 77 FR 17104 - Culturally Significant Objects Imported for Exhibition Determinations: “Ecstatic Alphabets/Heaps...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ecstatic Alphabets/Heaps of Language... determine that the objects to be included in the exhibition ``Ecstatic Alphabets/Heaps of...

  7. 76 FR 60112 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  8. 75 FR 30459 - Culturally Significant Objects Imported for Exhibition Determinations: “Dynasty and Divinity: Ife...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Dynasty and Divinity: Ife Art in... hereby determine that the objects to be included in the exhibition ``Dynasty and Divinity: Ife Art...

  9. 77 FR 77178 - Culturally Significant Objects Imported for Exhibition Determinations: “Pre-Raphaelites...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Pre-Raphaelites: Victorian Art and...: Victorian Art and Design, 1848-1900,'' imported from abroad for temporary exhibition within the...

  10. 77 FR 36329 - Culturally Significant Objects Imported for Exhibition Determinations: “Dead Sea Scrolls & The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Dead Sea Scrolls & The Bible Ancient... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Dead Sea...

  11. 78 FR 62354 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-18

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Dead Sea Scrolls: Life and Faith in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times'' ACTION... exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice was corrected...

  12. 77 FR 64373 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Dead Sea Scrolls: Life and Faith in Ancient Times,'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times... the exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice...

  13. 78 FR 16565 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Dead Sea Scrolls: Life and Faith in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times'' ACTION... exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice was corrected...

  14. 78 FR 24462 - Culturally Significant Objects Imported for Exhibition; Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... Culturally Significant Objects Imported for Exhibition; Determinations: ``The Dead Sea Scrolls: Life and Faith in Ancient Times'' Formerly Titled ``The Dead Sea Scrolls: Life and Faith in Biblical Times... the exhibition ``The Dead Sea Scrolls: Life and Faith in Biblical Times.'' The referenced notice...

  15. 77 FR 60506 - Culturally Significant Objects Imported for Exhibition Determinations: “Light and Shadows: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Light and Shadows: The Story of..., 2003), I hereby determine that certain of the objects to be included in the exhibition ``Light...

  16. 76 FR 53524 - Culturally Significant Objects Imported for Exhibition Determinations: “Light Years: Conceptual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Light Years: Conceptual Art and the..., 2003), I hereby determine that the objects to be included in the exhibition ``Light Years:...

  17. 76 FR 39974 - Culturally Significant Objects Imported for Exhibition Determinations: “Warhol: The Headlines”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ..., from on or about September 25, 2011, until on or about January 2, 2012, at The Andy Warhol Museum... Culturally Significant Objects Imported for Exhibition Determinations: ``Warhol: The Headlines'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Warhol: The...

  18. 76 FR 36166 - Culturally Significant Objects Imported for Exhibition; Determinations: “Gabriel von Max: Be...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Gabriel von Max: Be-Tailed Cousins... the exhibition ``Gabriel von Max: Be-Tailed Cousins and Phantasms of the Soul,'' imported from...

  19. 70 FR 3959 - Culturally Significant Objects Imported for Exhibition Determinations: “Max Ernst: A Retrospective”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2005-01-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Max Ernst: A Retrospective'' AGENCY... April 15, 2003 , I hereby determine that the objects to be included in the exhibition, ``Max Ernst:...

  20. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Artifacts From Auschwitz...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Artifacts From Auschwitz-Birkenau... of August 28, 2000, I hereby determine that the objects to be included in the exhibition...

  1. 77 FR 12102 - Culturally Significant Objects Imported for Exhibition Determinations: “Constable: Oil Sketches...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Constable: Oil Sketches From the V..., 2003), I hereby determine that the objects to be included in the exhibition ``Constable: Oil...

  2. 75 FR 5637 - Culturally Significant Objects Imported for Exhibition Determinations: “Architecture as Icon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Architecture as Icon: Perception and Representation of Architecture in Byzantine Art'' SUMMARY: Notice is hereby given of the following determinations... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Architecture...

  3. 75 FR 53012 - Culturally Significant Objects Imported for Exhibition Determinations: “Treasures of Moscow...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... exhibit objects at the Museum of Russian Icons, Clinton, MA, from on or about October 23, 2010, until on... Culturally Significant Objects Imported for Exhibition Determinations: ``Treasures of Moscow: Icons From the Andrey Rublev Museum'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...

  4. 78 FR 27470 - Culturally Significant Objects Imported for Exhibition Determinations: “Shaping Power: Luba...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... the exhibit objects at the Los Angeles County Museum of Art, Los Angeles, California, from on or about... Culturally Significant Objects Imported for Exhibition Determinations: ``Shaping Power: Luba Masterworks From the Royal Museum for Central Africa'' SUMMARY: Notice is hereby given of the following...

  5. 77 FR 38374 - Culturally Significant Objects Imported for Exhibition Determinations: “The Human Beast: German...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... exhibit objects at The San Diego Museum of Art, San Diego, CA, from on or about July 21, 2012, until on or... Culturally Significant Objects Imported for Exhibition Determinations: ``The Human Beast: German Expressionism at The San Diego Museum of Art'' SUMMARY: Notice is hereby given of the following...

  6. 78 FR 2478 - Culturally Significant Objects Imported for Exhibition Determinations: “Ming Masterpieces From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Ming Masterpieces From the Shanghai Museum'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority..., 2003), I hereby determine that the objects to be included in the exhibition ``Ming Masterpieces...

  7. 75 FR 13806 - Culturally Significant Objects Imported for Exhibition Determinations: “Loan From the Aura...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Loan From the Aura Collection of a... hereby determine that the object to be included in the exhibition ``Loan from the Aura Collection of...

  8. 76 FR 12399 - Culturally Significant Objects Imported for Exhibition Determinations: “Paris: Life & Luxury”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Paris: Life & Luxury'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Paris: Life & Luxury... objects are imported pursuant to loan agreements with the foreign owners or custodians. I also...

  9. 78 FR 53817 - Culturally Significant Objects Imported for Exhibition Determinations: “Venetian Glass by Carlo...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Venetian Glass by Carlo Scarpa: The... April 15, 2003, I hereby determine that the objects to be included in the exhibition ``Venetian Glass...

  10. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition Determinations: “Chagall: Love, War, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chagall: Love, War, and Exile... determine that the objects to be included in the exhibition ``Chagall: Love, War, and Exile,'' imported...

  11. 75 FR 18252 - Culturally Significant Object Imported for Exhibition Determinations: “Through African Eyes: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Through African Eyes: The European in... 15, 2003 , I hereby determine that the object to be included in the exhibition ``Through African...

  12. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Adapting the Eye: An...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Adapting the Eye: An Archive of the... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Adapting the...

  13. 77 FR 25780 - Culturally Significant Objects Imported for Exhibition Determinations: “Gold, Jasper, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gold, Jasper, and Carnelian: Johann... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Gold,...

  14. 77 FR 61468 - Culturally Significant Objects Imported for Exhibition Determinations: “Matisse: In Search of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Matisse: In Search of True Painting... determine that the objects to be included in the exhibition ``Matisse: In Search of True...

  15. 76 FR 53524 - Culturally Significant Objects Imported for Exhibition Determinations: “Mirror of the Buddha...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mirror of the Buddha: Early..., 2003), I hereby determine that the objects to be included in the exhibition ``Mirror of the...

  16. 75 FR 15764 - Culturally Significant Objects Imported for Exhibition Determinations: “Gods of Angkor: Bronzes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gods of Angkor: Bronzes From the... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Gods of...

  17. 76 FR 18291 - Culturally Significant Objects Imported for Exhibition Determinations: “Boris Mikhailov: Case...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Boris Mikhailov: Case History... Mikhailov: Case History,'' imported from abroad for temporary exhibition within the United States, are of... Art, New York, New York, from on or about May 26, 2011, until on or about September 5, 2011, and...

  18. 77 FR 56251 - Culturally Significant Objects Imported for Exhibition Determinations: “The Body Beautiful in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Body Beautiful in Ancient Greece... determine that the objects to be included in the exhibition ``The Body Beautiful in Ancient...

  19. 78 FR 79560 - Culturally Significant Objects Imported for Exhibition Determinations: “Khirbet el-Maqatir...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Khirbet el-Maqatir: History of a..., ``Khirbet el-Maqatir: History of a Biblical Site,'' imported from abroad for temporary exhibition within...

  20. 77 FR 53959 - Culturally Significant Object Imported for Exhibition Determinations: “Dancing Into Dreams, Maya...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Dancing Into Dreams, Maya Vases From..., 2003), I hereby determine that the object to be included in the exhibition ``Dancing Into Dreams,...

  1. 76 FR 56865 - Culturally Significant Objects Imported for Exhibition Determinations: “Degas and the Nude”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Degas and the Nude'' SUMMARY: Notice... objects to be included in the exhibition ``Degas and the Nude,'' imported from abroad for...

  2. 75 FR 37521 - Culturally Significant Objects Imported for Exhibition Determinations: “Eton College Myers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Eton College Myers Collection at Johns Hopkins University'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... 15, 2003 , I hereby determine that the objects to be included in the exhibition ``Eton College...

  3. 77 FR 73511 - Culturally Significant Objects Imported for Exhibition Determinations: “Arts of Islamic Lands...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Arts of Islamic Lands: Masterpieces... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Arts of...

  4. 76 FR 23642 - Culturally Significant Objects Imported for Exhibition Determinations: “Marajo: Ancient Ceramics...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Marajo: Ancient Ceramics at the... ``Marajo: Ancient Ceramics at the Mouth of the Amazon'' imported from abroad for temporary...

  5. 76 FR 70805 - Culturally Significant Objects Imported for Exhibition Determinations: “The Renaissance Portrait...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Renaissance Portrait From... ``The Renaissance Portrait from Donatello to Bellini,'' imported from abroad for temporary...

  6. 78 FR 8682 - Culturally Significant Objects Imported for Exhibition Determinations: “Henri Labrouste...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Henri Labrouste: Structure Brought to Light'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...

  7. 76 FR 53705 - Culturally Significant Objects Imported for Exhibition; Determinations: “Seductive Luxury and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Seductive Luxury and Innovation... ``Seductive Luxury and Innovation: The Furniture of Abraham and David Roentgen,'' imported from abroad...

  8. 76 FR 15358 - Culturally Significant Objects Imported for Exhibition Determinations: “Before the Pyramids: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Before the Pyramids: The Origins of... ``Before the Pyramids: The Origins of Egyptian Civilization'' imported from abroad for temporary...

  9. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Dancing Around the Bride...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Dancing Around the Bride: Cage... ``Dancing Around the Bride: Cage, Cunningham, Johns, Rauschenberg, and Duchamp,'' imported from abroad...

  10. 77 FR 53248 - Culturally Significant Objects Imported for Exhibition Determinations: “Mantegna to Matisse...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mantegna to Matisse: Master Drawings... Matisse: Master Drawings From The Courtauld Gallery,'' imported from abroad for temporary...

  11. 77 FR 7655 - Culturally Significant Objects Imported for Exhibition Determinations: “Inventing the Modern...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Inventing the Modern World: Decorative Arts at the World's Fairs, 1851-1939'' SUMMARY: Notice is hereby given of the following... ``Inventing the Modern World: Decorative Arts at the World's Fairs, 1851-1939'' imported from abroad...

  12. 77 FR 48582 - Culturally Significant Objects Imported for Exhibition Determinations: Terracotta Bell-Krater...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: Terracotta Bell-Krater Attributed to..., 2003), I hereby determine that the object Terracotta Bell-Krater attributed to the Altamura...

  13. 76 FR 49832 - Culturally Significant Object Imported for Exhibition Determinations: “Warhol: The Headlines”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... about January 2, 2012, at The Andy Warhol Museum, Pittsburgh, Pennsylvania, from on or about October 14... Culturally Significant Object Imported for Exhibition Determinations: ``Warhol: The Headlines'' ACTION..., ``Warhol: The Headlines.'' The referenced notice is corrected to add one additional object to be...

  14. 78 FR 41972 - Culturally Significant Objects Imported for Exhibition Determinations: “Kongo Across the Waters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE...,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The..., Florida, from on or about October 22, 2013, until on or about March 23, 2014, the Jimmy...

  15. 75 FR 1680 - Culturally Significant Objects Imported for Exhibition: Determinations: “Giovanni Boldini in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Paris,'' imported from abroad for temporary ] exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners or custodians....

  16. 78 FR 51803 - Culturally Significant Objects Imported for Exhibition Determinations: “Charles Marville...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority...: Photographer of Paris,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners...

  17. 75 FR 21384 - Culturally Significant Objects Imported for Exhibition Determinations: “The Glory of Ukraine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``The Glory of Ukraine: Sacred Images... Ukraine: Sacred Images from the 11th to the 19th Centuries,'' imported from abroad for temporary... be determined, is in the national interest. Public Notice of these Determinations is ordered to...

  18. 76 FR 81004 - Culturally Significant Objects Imported for Exhibition Determinations: “Woman in Blue, Against...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Woman in Blue, Against Blue Water..., 2003), I hereby determine that the object ``Woman in Blue, Against Blue Water'' by Edvard...

  19. 75 FR 17197 - Culturally Significant Objects Imported for Exhibition Determinations: “Cyprus: Crossroads of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... from abroad for temporary exhibition within the United States, are of cultural significance. The... of Natural History, Washington, DC, from on or about September 1, 2010, until on or about April 15... Professional and Cultural Exchanges, Bureau of Educational and Cultural Affairs, Department of State....

  20. 78 FR 61871 - Culturally Significant Objects Imported for Exhibition Determinations: “focus: Monika Baer” and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-04

    ... the Williams College Museum of Art,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with foreign...; the Williams College Museum of Art, Williamstown, MA, from on or about February 22, 2014, until on...

  1. 77 FR 54647 - Culturally Significant Objects Imported for Exhibition Determinations: “Manet: Portraying Life”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Imported for Exhibition Determinations: ``Manet: Portraying Life'' SUMMARY: Notice is hereby given of the... exhibition ``Manet: Portraying Life,'' imported from abroad for temporary exhibition within the United...

  2. 76 FR 44977 - Culturally Significant Objects Imported for Exhibition Determinations: “De Kooning: A Retrospective”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... Exhibition Determinations: ``De Kooning: A Retrospective'' SUMMARY: Notice is hereby given of the following... exhibition ``De Kooning: A Retrospective,'' imported from abroad for temporary exhibition within the...

  3. 77 FR 46146 - Culturally Significant Objects Imported for Exhibition Determinations: “Shock of the News”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ... Exhibition Determinations: ``Shock of the News'' SUMMARY: Notice is hereby given of the following... exhibition ``Shock of the News,'' imported from abroad for temporary exhibition within the United States,...

  4. 77 FR 56697 - Culturally Significant Object Imported for Exhibition Determinations: “Steve McQueen”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Imported for Exhibition Determinations: ``Steve McQueen'' SUMMARY: Notice is hereby given of the following... exhibition ``Steve McQueen,'' imported from abroad for temporary exhibition within the United States, is...

  5. 77 FR 56698 - Culturally Significant Objects Imported for Exhibition Determinations: “Opera Nobile...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... for Exhibition Determinations: ``Opera Nobile: Masterpieces From Ancient Italy'' SUMMARY: Notice is... objects to be included in the exhibition ``Opera Nobile: Masterpieces from Ancient Italy,'' imported...

  6. 78 FR 52996 - Culturally Significant Objects Imported for Exhibition Determinations: “Face to Face: Flanders...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ..., and Renaissance Painting'' Exhibition SUMMARY: Notice is hereby given of the following determinations...: Flanders, Florence, and Renaissance Painting,'' imported from abroad for temporary exhibition within...

  7. 77 FR 3320 - Culturally Significant Objects Imported for Exhibition Determinations: “Renoir, Impressionism...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... Exhibition Determinations: ``Renoir, Impressionism, and Full-Length Painting'' SUMMARY: Notice is hereby... objects to be included in the exhibition ``Renoir, Impressionism, and Full-Length Painting,''...

  8. 75 FR 53731 - Culturally Significant Objects Imported for Exhibition Determinations: “Contemporary Argentine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... for Exhibition Determinations: ``Contemporary Argentine Masterworks'' SUMMARY: Notice is hereby given... hereby determine that the objects to be included in the exhibition ``Contemporary Argentine...

  9. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Johan Zoffany RA: Society...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... for Exhibition Determinations: ``Johan Zoffany RA: Society Observed'' SUMMARY: Notice is hereby given... objects to be included in the exhibition ``Johan Zoffany RA: Society Observed,'' imported from abroad...

  10. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... for Exhibition Determinations: ``Balthus: Cats and Girls--Paintings and Provocations'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Balthus: Cats and...

  11. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Anglo-Saxon Hoard: Gold...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... for Exhibition Determinations: ``Anglo-Saxon Hoard: Gold From England's Dark Ages'' SUMMARY: Notice is... objects to be included in the exhibition ``Anglo-Saxon Hoard: Gold From England's Dark Ages,''...

  12. 78 FR 39435 - Culturally Significant Objects Imported for Exhibition; Determinations: “Magritte: The Mystery of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... Exhibition; Determinations: ``Magritte: The Mystery of the Ordinary, 1926-1938'' SUMMARY: Notice is hereby... objects to be included in the exhibition ``Magritte: The Mystery of the Ordinary, 1926-1928,''...

  13. 75 FR 38589 - Culturally Significant Objects Imported for Exhibition Determinations: “Salvador Dali: The Late...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... October 19, 1999, as amended, and Delegation of Authority No. 257 of April 15, 2003 , I hereby determine... exhibition or display of the exhibit objects at the High Museum of Art, Atlanta, GA, from on or about...

  14. 77 FR 54647 - Culturally Significant Objects Imported for Exhibition Determinations: “African Art, New York...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... for Exhibition Determinations: ``African Art, New York, and the Avant-Garde'' SUMMARY: Notice is... objects to be included in the exhibition ``African Art, New York, and the Avant- Garde,'' imported...

  15. 77 FR 56697 - Culturally Significant Objects Imported for Exhibition Determinations: “The English Prize: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... for Exhibition Determinations: ``The English Prize: The Capture of the Westmorland, an Episode of the..., 2003), I hereby determine that the objects to be included in the exhibition ``The English Prize:...

  16. 77 FR 74048 - Culturally Significant Object Imported for Exhibition Determinations: “Connecting Collections...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... Connections. 50 Years of Pre-Columbian Art at Dumbarton Oaks'' SUMMARY: Notice is hereby given of the... exhibition ``Connecting Collections: Collecting Connections. 50 Years of Pre-Columbian Art at Dumbarton Oaks... that the exhibition or display of the exhibit object at Dumbarton Oaks, Washington, DC, from on...

  17. 78 FR 62935 - Culturally Significant Object Imported for Exhibition Determinations: “A Loan From the Vatican...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... Culturally Significant Object Imported for Exhibition Determinations: ``A Loan From the Vatican Museums... hereby determine that the object to be included in the exhibition ``A Loan from the Vatican Museums... temporary exhibition within the United States, is of cultural significance. The object is imported...

  18. Inviting Learning: An Exhibition of Risk and Enrichment in Adult Education Practice.

    ERIC Educational Resources Information Center

    Willis, Peter

    This study explores adult education practice by using an expressive research method based on using the metaphor of an exhibition as a vehicle for presenting and reflecting on seven episodes in the researcher's two decades of teaching at various locations throughout Australia. In accordance with the metaphor, the study report contains the following…

  19. 76 FR 40419 - Culturally Significant Objects Imported for Exhibition Determinations: “Prints and the Pursuit of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Prints and the Pursuit of Knowledge... the exhibition ``Prints and the Pursuit of Knowledge in Early Modern Europe,'' imported from...

  20. 76 FR 58074 - Culturally Significant Objects Imported for Exhibition Determinations: “Sanja Iveković: Sweet...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Sanja Ivekovi : Sweet Violence... determine that the objects to be included in the exhibition ``Sanja Ivekovi : Sweet Violence,''...

  1. 76 FR 58075 - Culturally Significant Objects Imported for Exhibition Determinations: “Sanja Iveković: Sweet...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Sanja Ivekovi : Sweet Violence... determine that the objects to be included in the exhibition ``Sanja Ivekovi : Sweet Violence,''...

  2. 78 FR 79559 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Experience of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Experience of Seeing... determine that the objects to be included in the exhibition ``Mir : The Experience of Seeing,''...

  3. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Mir : The Dutch...

  4. 75 FR 74126 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Guitars 1912-1914”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Picasso: Guitars 1912-1914'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Picasso: Guitars...

  5. 78 FR 55772 - Culturally Significant Objects Imported for Exhibition Determinations: “American Adversaries...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... Copley in a Transatlantic World'' SUMMARY: Notice is hereby given of the following determinations... Adversaries: West and Copley in a Transatlantic World,'' imported from abroad for temporary exhibition...

  6. 78 FR 56980 - Culturally Significant Objects Imported for Exhibition Determinations: “Francesco Vanni: Art in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... Renaissance Siena'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Late Renaissance Siena,'' imported from abroad for temporary exhibition within the United States,...

  7. 76 FR 2438 - Culturally Significant Objects Imported for Exhibition Determinations: “Kings, Queens, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... Early Renaissance France'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``Kings, Queens, and Courtiers: Art in Early Renaissance France'' imported from...

  8. 75 FR 60490 - Culturally Significant Objects Imported for Exhibition Determinations: “Haremhab, The General Who...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... King'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Haremhab, The General Who Became King,'' imported from abroad for temporary exhibition within the...

  9. 77 FR 51606 - Culturally Significant Objects Imported for Exhibition Determinations: “Extravagant Inventions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... Furniture of the Roentgens,'' Formerly Titled ``Seductive Luxury and Innovation: The Furniture of Abraham... State pertaining to the exhibition ``Seductive Luxury and Innovation: The Furniture of Abraham and...

  10. 77 FR 34121 - Culturally Significant Objects Imported for Exhibition Determinations: “Revealing the African...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Renaissance Europe'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Presence in Renaissance Europe'' imported from abroad for temporary exhibition within the United...

  11. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “Treasures of Heaven...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ..., and Devotion in Medieval Europe'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Treasures of Heaven: Saints, Relics, and Devotion in Medieval Europe,'' imported...

  12. 77 FR 15839 - Culturally Significant Objects Imported for Exhibition Determinations: “Making a Presence: F...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... Artistic Photography'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the.... Holland Day in Artistic Photography,'' imported from abroad for temporary exhibition within the...

  13. 76 FR 28121 - Culturally Significant Objects Imported for Exhibition Determinations: “National Geographic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... Earth'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``National Geographic Treasures of the Earth'' imported from abroad for temporary exhibition within...

  14. 75 FR 47337 - Culturally Significant Objects Imported for Exhibition Determinations: “German Impressionist...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Painting: Liebermann-- Corinth--Slevogt'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``German Impressionist Landscape Painting: Liebermann--Corinth--Slevogt,''...

  15. 75 FR 47338 - Culturally Significant Objects Imported for Exhibition Determinations: “The Nepalese Legacy in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``The Nepalese Legacy in Tibetan Painting,'' imported from abroad for temporary exhibition within...

  16. 76 FR 60113 - Culturally Significant Objects Imported for Exhibition Determinations: “Masters of Venice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Paintings of Passion and Power from Kunsthistorisches Museum, Vienna'' SUMMARY: Notice is hereby given of... included in the exhibition ``Masters of Venice: Renaissance Paintings of Passion and Power...

  17. 78 FR 55772 - Culturally Significant Object Imported for Exhibition Determinations: “Beauty Revealed: Images of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... Qing Dynasty Chinese Painting'' SUMMARY: Notice is hereby given of the following determinations...: Images of Women in Qing Dynasty Chinese Painting,'' imported from abroad for temporary exhibition...

  18. 75 FR 52385 - Culturally Significant Objects Imported for Exhibition Determinations: “Paintings From the Reign...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... Imported for Exhibition Determinations: ``Paintings From the Reign of Victoria: The Royal Holloway..., ``Paintings from the Reign of Victoria: The Royal Holloway Collection, London'' would leave the United...

  19. 78 FR 5556 - Culturally Significant Objects Imported for Exhibition Determinations: “Frida & Diego: Passion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority..., Politics and Painting,'' imported from abroad for temporary exhibition within the United States, are...

  20. 77 FR 24554 - Culturally Significant Objects Imported for Exhibition; Determinations: “Quay Brothers: On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... Pharmacist's Prescription for Lip-Reading Puppets'' AGENCY: State Department. ACTION: Notice. SUMMARY: Notice... objects to be included in the exhibition ``Quay Brothers: On Deciphering the Pharmacist's Prescription...

  1. 77 FR 7229 - Culturally Significant Objects Imported for Exhibition Determinations: “Nomads and Networks: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... and Culture of Kazakhstan'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... Networks: The Ancient Art and Culture of Kazakhstan,'' imported from abroad for temporary exhibition...

  2. 77 FR 37730 - Culturally Significant Objects Imported for Exhibition Determinations: “Nomads and Networks: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... and Culture of Kazakhstan'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... Networks: The Ancient Art and Culture of Kazakhstan,'' imported from abroad for temporary exhibition...

  3. 76 FR 77299 - Culturally Significant Objects Imported for Exhibition Determinations: “Civic Pride: Group...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Amsterdam'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Portraits from Amsterdam,'' imported from abroad for temporary exhibition within the United States, are...

  4. 77 FR 4614 - Culturally Significant Objects Imported for Exhibition Determinations: “Children of the Plumed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... Legacy of Quetzalcoatl in Ancient Mexico'' SUMMARY: Notice is hereby given of the following... exhibition ``Children of the Plumed Serpent: The Legacy of Quetzalcoatl in Ancient Mexico,'' imported...

  5. 75 FR 9013 - Culturally Significant Objects Imported for Exhibition Determinations: “Vienna Circa 1780: An...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Silver Service Rediscovered'' SUMMARY: Notice is hereby given of the following determinations: Pursuant...: An Imperial Silver Service Rediscovered,'' imported from abroad for temporary exhibition within...

  6. 77 FR 73731 - Culturally Significant Objects Imported for Exhibition Determinations: “Masterpieces of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... Korea'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Joseon Dynasty from the National Museum of Korea,'' imported from abroad for temporary exhibition...

  7. 75 FR 43225 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust-Uniforms...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ..., and Shoes'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``The Holocaust--Uniforms, Canisters, and Shoes,'' imported from abroad for temporary exhibition...

  8. 76 FR 4987 - Culturally Significant Objects Imported for Exhibition Determinations: “Treasures From the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ...'s Crown Jewels'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... ``Treasures from the Hermitage: Russia's Crown Jewels,'' imported from abroad for temporary exhibition...

  9. 75 FR 45194 - Culturally Significant Objects Imported for Exhibition Determinations: “Drawing from Nature...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... Max Liebermann, Lovis Corinth, and Max Slevogt'' SUMMARY: Notice is hereby given of the following... objects to be included in the exhibition ``Drawing from Nature: Landscapes by Max Liebermann, Lovis Corinth, and Max Slevogt,'' imported from abroad for temporary exhibition within the United States, are...

  10. 78 FR 62326 - Culturally Significant Objects Imported for Exhibition Determinations: “Toulouse-Lautrec and La...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-16

    ...: Paris 1880- 1910'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... the exhibition ``Toulouse-Lautrec and La Vie Moderne: Paris 1880-1910,'' imported from abroad for... pursuant to loan agreements with the foreign owners or custodians. I also determine that the exhibition...

  11. 75 FR 53731 - Culturally Significant Objects Imported for Exhibition Determinations: “Sheila Hicks: 50 Years”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... for Exhibition Determinations: ``Sheila Hicks: 50 Years'' SUMMARY: Notice is hereby given of the.... 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Sheila Hicks: 50 Years,'' imported from abroad...

  12. 78 FR 32000 - Culturally Significant Objects Imported for Exhibition Determinations: “Before and After the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-28

    ...: Anishinaabe Artists of the Great Lakes'' SUMMARY: Notice is hereby given of the following determinations... the Horizon: Anishinaabe Artists of the Great Lakes,'' imported from abroad for temporary exhibition... 3, 2013, until on or about June 15, 2014, and at possible additional exhibitions or venues yet to...

  13. 77 FR 26599 - Culturally Significant Objects Imported for Exhibition Determinations: “The Artist in the Garden”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... exhibit objects at The New York Botanical Garden, Bronx, NY, from on or about May 19, 2012, until on or... Culturally Significant Objects Imported for Exhibition Determinations: ``The Artist in the Garden'' SUMMARY... objects to be included in the exhibition ``The Artist in the Garden'' imported from abroad for...

  14. 75 FR 54691 - Culturally Significant Objects Imported for Exhibition Determinations: “The Vorticists: Rebel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... London and New York, 1914-18'' SUMMARY: Notice is hereby given of the following determinations: Pursuant... the exhibition ``The Vorticists: Rebel Artists in London and New York, 1914-18,'' imported from...

  15. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dead Sea Scrolls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Changed the World'' Summary: Notice is hereby given of the following determinations: Pursuant to the... Changed the World,'' imported from abroad for temporary exhibition within the United States, are...

  16. 76 FR 59767 - Culturally Significant Objects Imported for Exhibition Determinations: “Contested Visions in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... Colonial World'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Spanish Colonial World'' imported from abroad for temporary exhibition within the United States, are...

  17. 78 FR 71022 - Culturally Significant Objects Imported for Exhibition Determinations: “Christopher Williams: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Line of Happiness'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Product Line of Happiness,'' imported from abroad for temporary exhibition within the United States,...

  18. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “Hendrick Avercamp (1585...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Little Ice Age'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Little Ice Age,'' imported from abroad for temporary exhibition within the United States, are of...

  19. 76 FR 71616 - Culturally Significant Objects Imported for Exhibition Determinations: “The Steins Collect...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ..., and the Parisian Avant-Garde'' Exhibition ACTION: Notice, correction. SUMMARY: On April 1, 2011..., and the Parisian Avant-Garde.'' The referenced notice is corrected as to the number of objects...

  20. 78 FR 51803 - Culturally Significant Objects Imported for Exhibition Determinations: “Vasily Kandinsky: From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... to the Bauhaus, 1910-1925'' SUMMARY: Notice is hereby given of the following determinations: Pursuant...: From Blaue Reiter to the Bauhaus, 1910-1925,'' imported from abroad for temporary exhibition within...

  1. 76 FR 5236 - Culturally Significant Objects Imported for Exhibition Determinations: “Pastel Portraits: Images...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ...-Century Europe'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... ``Pastel Portraits: Images of 18th-Century Europe,'' imported from abroad for temporary exhibition...

  2. 75 FR 51518 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Masterpieces...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... National Picasso, Paris'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... agreement with the foreign owner or custodian. I also determine that the exhibition or display of...

  3. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “Chaos and Classicism: Art...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ..., Italy, and Germany, 1918-1936'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Chaos and Classicism: Art in France, Italy, and Germany, 1918-1936,'' imported...

  4. 78 FR 24288 - Culturally Significant Objects Imported for Exhibition Determinations: “Frida Kahlo, Diego Rivera...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... Masterpieces of Modern Mexico: The Jacques and Natasha Gelman Collection'' SUMMARY: Notice is hereby given of... Natasha Gelman Collection,'' imported from abroad for temporary exhibition within the United States,...

  5. 77 FR 10599 - Culturally Significant Objects Imported for Exhibition Determinations: “Elegance and Refinement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ...-Life Paintings of Willem van Aelst'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Elegance and Refinement: The Still-Life Paintings of Willem van Aelst,''...

  6. 77 FR 57637 - Culturally Significant Objects Imported for Exhibition Determinations: “The Place of Provenance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-18

    ... Styles in Tibetan Painting'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``The Place of Provenance--Regional Styles in Tibetan Painting,'' imported from...

  7. 77 FR 12103 - Culturally Significant Objects Imported for Exhibition Determinations: “Colorful Realm: Japanese...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ...-Flower Paintings by It Jakuch (1716-1800)'' SUMMARY: Notice is hereby given of the following... exhibition ``Colorful Realm: Japanese Bird-and-Flower Paintings by It Jakuch (1716-1800),'' imported...

  8. 75 FR 3272 - Culturally Significant Objects Imported for Exhibition Determinations: “The Sacred Made Real...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... Painting and Sculpture 1600-1700'' SUMMARY: Notice is hereby given of the following determinations... Real: Spanish Painting and Sculpture 1600-1700,'' imported from abroad for temporary exhibition...

  9. 77 FR 62311 - Culturally Significant Objects Imported for Exhibition Determinations: “Royal Treasures From the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-12

    ...- Antoinette'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Louvre: Louis XIV to Marie-Antoinette'' imported from abroad for temporary exhibition within the...

  10. 77 FR 6621 - Culturally Significant Objects Imported for Exhibition Determinations: “The Rylands Haggadah...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... Jewish Art in Context'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the...: Medieval Jewish Art in Context,'' imported from abroad for temporary exhibition within the United...

  11. 78 FR 60994 - Culturally Significant Objects Imported for Exhibition Determinations: “In Grand Style...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Korean Art During the Joseon Dynasty'' SUMMARY: Notice is hereby given of the following determinations...: Celebrations in Korean Art during the Joseon Dynasty,'' imported from abroad for temporary exhibition...

  12. 78 FR 33465 - Culturally Significant Objects Imported for Exhibition Determinations: “Interwoven Globe: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Textile Trade, 1500- 1800'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...: The Worldwide Textile Trade, 1500-1800,'' imported from abroad for temporary exhibition within...

  13. 78 FR 3067 - Culturally Significant Objects Imported for Exhibition Determinations: “Looking East: Rubens's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... With Asia'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... Encounter with Asia,'' imported from abroad for temporary exhibition within the United States, are...

  14. The adaptive significance of adult neurogenesis: an integrative approach

    PubMed Central

    Konefal, Sarah; Elliot, Mick; Crespi, Bernard

    2013-01-01

    Adult neurogenesis in mammals is predominantly restricted to two brain regions, the dentate gyrus (DG) of the hippocampus and the olfactory bulb (OB), suggesting that these two brain regions uniquely share functions that mediate its adaptive significance. Benefits of adult neurogenesis across these two regions appear to converge on increased neuronal and structural plasticity that subserves coding of novel, complex, and fine-grained information, usually with contextual components that include spatial positioning. By contrast, costs of adult neurogenesis appear to center on potential for dysregulation resulting in higher risk of brain cancer or psychological dysfunctions, but such costs have yet to be quantified directly. The three main hypotheses for the proximate functions and adaptive significance of adult neurogenesis, pattern separation, memory consolidation, and olfactory spatial, are not mutually exclusive and can be reconciled into a simple general model amenable to targeted experimental and comparative tests. Comparative analysis of brain region sizes across two major social-ecological groups of primates, gregarious (mainly diurnal haplorhines, visually-oriented, and in large social groups) and solitary (mainly noctural, territorial, and highly reliant on olfaction, as in most rodents) suggest that solitary species, but not gregarious species, show positive associations of population densities and home range sizes with sizes of both the hippocampus and OB, implicating their functions in social-territorial systems mediated by olfactory cues. Integrated analyses of the adaptive significance of adult neurogenesis will benefit from experimental studies motivated and structured by ecologically and socially relevant selective contexts. PMID:23882188

  15. Significant Adults in the Teacher-Learning Environment

    ERIC Educational Resources Information Center

    Morgan, Harry

    1972-01-01

    A primary goal of schooling is to create a teaching-learning atmosphere that facilitates growth and development. As significant adults in the lives of children, we should strive to be facilitators of learning rather than omnipotent persons who have all the knowledge that should be imparted to learners. (Author)

  16. 75 FR 21385 - Culturally Significant Objects Imported for Exhibition Determinations: “Cleopatra: The Search for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Queen of Egypt'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Queen of Egypt,'' imported from abroad for temporary exhibition within the United States, are of... of Art, Fort Lauderdale, FL, from on or about January 1, 2013, until on or about May 31, 2013; and...

  17. 77 FR 2118 - Culturally Significant Objects Imported for Exhibition Determinations: “The Steins Collect...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-13

    ... and the Parisian Avant-Garde'' ACTION: Notice, correction. SUMMARY: On April 1, 2011, notice was... Avant-Garde.'' This notice was corrected by a November 18, 2011, notice published on page 71616 of the... and the Parisian Avant-Garde'' imported from abroad for temporary exhibition within the United...

  18. 76 FR 33398 - Culturally Significant Objects Imported for Exhibition Determinations; “Lyonel Feininger: At the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... World'' Summary: Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of... ``Lyonel Feininger: At the Edge of the World,'' imported from abroad for temporary exhibition within...

  19. 76 FR 27742 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Masterpieces...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-12

    ... National Picasso, Paris'' Summary: Notice is hereby given of the following determinations: Pursuant to the... ``Picasso: Masterpieces from the Mus e National Picasso, Paris,'' imported from abroad for temporary... loan agreement with the foreign owner or custodian. I also determine that the exhibition or display...

  20. 77 FR 32168 - Culturally Significant Object Imported for Exhibition Determinations: “Elegance and Refinement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ...-Life Paintings of Willem van Aelst'' AGENCY: Department of State. ACTION: Notice, correction. SUMMARY... Refinement: The Still-Life Paintings of Willem van Aelst.'' The referenced notice is corrected here to... in the exhibition ``Elegance and Refinement: The Still-Life Paintings of Willem van Aelst,''...

  1. 75 FR 71787 - Culturally Significant Objects Imported for Exhibition Determinations: “Salvator Rosa: Bandits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... and Magic'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Salvator Rosa: Bandits, Wilderness and Magic'', imported from abroad for temporary exhibition within the... objects at the Kimbell Art Museum, Fort Worth, TX, from on or about December 12, 2010, until on or...

  2. 77 FR 53959 - Culturally Significant Objects Imported for Exhibition Determinations: “Roads of Arabia...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... History of the Kingdom of Saudi Arabia'' SUMMARY: Notice is hereby given of the following determinations...: Archaeology and the History of the Kingdom of Saudi Arabia,'' imported from abroad for temporary exhibition... about November 17, 2012, until on or about February 24, 2013; the Museum of Fine Arts, Houston...

  3. 75 FR 8424 - Culturally Significant Objects Imported for Exhibition Determinations: “Leaves From an Austrian...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236 of... on or about June 1, 2010, until on or about June 1, 2012, and at possible additional exhibitions or...- 5, L/PD, Fifth Floor, Washington, DC 20522-0505. Dated: February 17, 2010. Maura M. Pally,...

  4. 78 FR 44188 - Culturally Significant Objects Imported for Exhibition Determinations: “Before and After the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ...: Anishinaabe Artists of the Great Lakes'' AGENCY: Department of State. ACTION: Notice, correction. SUMMARY: On...: Anishinaabe Artists of the Great Lakes.'' The referenced notice is corrected here to include additional... exhibition ``Before and after the Horizon: Anishinaabe Artists of the Great Lakes,'' imported from abroad...

  5. Astronomy's New Messengers: A traveling exhibit to reach out to a young adult audience

    NASA Astrophysics Data System (ADS)

    Cavaglià, Marco; Hendry, Martin; Márka, Szabolcs; Reitze, David H.; Riles, Keith

    2010-05-01

    The Laser Interferometer Gravitational-wave Observatory exhibit Astronomy's New Messengers: Listening to the Universe with Gravitational Waves is traveling to colleges, universities, museums and other public institutions throughout the United States. In 2010, an extended version of this exhibit will appear in a New York City venue that is accessible to a large and diverse cross section of the general public. Astronomy's New Messengers primarily communicates with an adolescent and young adult audience, potentially inspiring them into the field of science. Acknowledging that this audience is traditionally a difficult one to attract, the exhibit publicly announces itself in a charismatic fashion to reach its principal goals of broadening the community of people interested in science and encouraging interest in science among young people.

  6. 77 FR 51843 - Culturally Significant Objects Imported for Exhibition Determinations: “Plants of Virtue and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ...On August 14, 2012, notice was published on pages 48582-3 of the Federal Register (volume 77, number 157) of determinations made by the Department of State pertaining to the object ``Plants of Virtue and Rocks by a Stream'' by Shitao. The referenced notice is corrected here to change the name of the exhibition in which that object will appear to ``The Artful Recluse: Painting, Poetry, and......

  7. Adolescents exhibit behavioral differences from adults during instrumental learning and extinction.

    PubMed

    Sturman, David A; Mandell, Daniel R; Moghaddam, Bita

    2010-02-01

    Adolescence is associated with the development of brain regions linked to cognition and emotion. Such changes are thought to contribute to the behavioral and neuropsychiatric vulnerabilities of this period. We compared adolescent (Postnatal Days 28-42) and adult (Postnatal Day 60+) rats as they performed a simple instrumental task and extinction. Rats were trained to poke into a hole for a food-pellet reinforcer. After six days of training, rats underwent extinction sessions in which the previously rewarded behavior was no longer reinforced. During extinction, we examined the effects of continued presentation of a cue light and food restriction. Adults and adolescents exhibited similar performance during training, although adolescents made more task-irrelevant pokes, consistent with increased exploration. Adults made more premature pokes, which could indicate a more exclusive focus on the task. During extinction, adolescents made more perseverative (previously reinforced) pokes than adults. This behavior was strongly modulated by the combination of motivational factors present (food restriction and cue light), indicating that adolescents were differentially sensitive to them. Furthermore, food restriction induced greater open-field activity in adolescents but not in adults. Thus, as the neural circuitry of motivated behavior develops substantially during adolescence, so too does the behavioral sensitivity to motivational factors. Understanding how such factors differently affect adolescents may shed light on mechanisms that lead to the development of disorders that are manifested during this period.

  8. 78 FR 16565 - Culturally Significant Objects Imported for Exhibition Determinations: “Le Corbusier: An Atlas of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Le Corbusier: An Atlas of Modern..., 2003), I hereby determine that the objects to be included in the exhibition ``Le Corbusier: An Atlas...

  9. 76 FR 39974 - Culturally Significant Object Imported for Exhibition Determinations: “Titian's Woman in a Blue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... Culturally Significant Object Imported for Exhibition Determinations: ``Titian's Woman in a Blue Dress `La... ``Titian's Woman in a Blue Dress `La Bella','' imported from abroad for temporary exhibition within the..., Assistant Secretary, Bureau of Educational and Cultural Affairs, Department of State. BILLING CODE 4710-05-P...

  10. 78 FR 58378 - Culturally Significant Objects Imported for Exhibition Determinations: “Peru: Kingdoms of the Sun...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Peru: Kingdoms of the Sun and the..., 2003), I hereby determine that the objects to be included in the exhibition ``Peru: Kingdoms of the...

  11. 76 FR 51458 - Culturally Significant Objects Imported for Exhibition Determinations: “Wonder of the Age: Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Wonder of the Age: Master Painters... Age: Master Painters of India, 1100-1900,'' imported from abroad for temporary exhibition within...

  12. 76 FR 56492 - Culturally Significant Objects Imported for Exhibition Determinations: “Antico: The Golden Age of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Antico: The Golden Age of..., 2003), I hereby determine that the objects to be included in the exhibition ``Antico: The Golden Age...

  13. 77 FR 2341 - Culturally Significant Objects Imported for Exhibition Determinations: “The Cult of Beauty: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Cult of Beauty: The Victorian... Beauty: The Victorian Avant- Garde, 1860-1900,'' imported from abroad for temporary exhibition within...

  14. 77 FR 43644 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantine Art in the Mary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantine Art in the Mary and Michael Jaharis Galleries of Greek, Roman and Byzantine Art'' SUMMARY: Notice is hereby given of the... exhibition ``Byzantine Art in the Mary and Michael Jaharis Galleries of Greek, Roman and Byzantine...

  15. 77 FR 8943 - Culturally Significant Objects Imported for Exhibition Determinations: “The Dawn of Egyptian Art”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Dawn of Egyptian Art'' SUMMARY... objects to be included in the exhibition ``The Dawn of Egyptian Art,'' imported from abroad for...

  16. 77 FR 56909 - Culturally Significant Objects Imported for Exhibition Determinations: “Tokyo 1955-70: A New...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tokyo 1955-70: A New Avant-Garde... determine that the objects to be included in the exhibition ``Tokyo 1955-70: A New Avant-Garde,''...

  17. 76 FR 65559 - Culturally Significant Objects Imported for Exhibition Determinations: “Mummy: Secrets of the Tomb”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mummy: Secrets of the Tomb'' SUMMARY... objects to be included in the exhibition ``Mummy: Secrets of the Tomb'' imported from abroad for...

  18. 76 FR 45646 - Culturally Significant Objects Imported for Exhibition Determinations: “5,000 Years of Chinese...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``5,000 Years of Chinese Jade..., 2003), I hereby determine that the objects to be included in the exhibition ``5,000 Years of...

  19. 77 FR 31421 - Culturally Significant Objects Imported for Exhibition Determinations: “Portrait of Helena de Kay”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Portrait of Helena de Kay'' SUMMARY... object to be included in the exhibition ``Portrait of Helena de Kay,'' imported from abroad for...

  20. 75 FR 6249 - Culturally Significant Objects Imported for Exhibition Determinations: “Fiery Pool: The Maya and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Fiery Pool: The Maya and the Mythic... hereby determine that the objects to be included in the exhibition ``Fiery Pool: The Maya and the...

  1. 78 FR 77771 - Culturally Significant Object Imported for Exhibition Determinations: “Love and Play: A Pair of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Love and Play: A Pair of Paintings by..., I hereby determine that the object to be included in the exhibition ``Love and Play: A Pair...

  2. 75 FR 38589 - Culturally Significant Objects Imported for Exhibition Determinations: “The Origins of Writing in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Origins of Writing in the... hereby determine that the objects to be included in the exhibition ``The Origins of Writing in...

  3. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition Determination: “Heaven and Earth: Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Culturally Significant Objects Imported for Exhibition Determination: ``Heaven and Earth: Art of Byzantium... determinations made by the Department of State pertaining to the exhibition ``Heaven and Earth: Art of Byzantium... ``Heaven and Earth: Art of Byzantium from Greek Collections,'' at the Art Institute of Chicago,...

  4. 75 FR 13805 - Culturally Significant Objects Imported for Exhibition Determinations: “Race to the End of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Race to the End of the Earth... that the objects to be included in the exhibition ``Race to the End of the Earth,'' imported...

  5. 77 FR 27533 - Culturally Significant Objects Imported for Exhibition Determinations: “Ends of the Earth: Land...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ends of the Earth: Land Art to 1974... determine that the objects to be included in the exhibition ``Ends of the Earth: Land Art to 1974''...

  6. 76 FR 42158 - Culturally Significant Objects Imported for Exhibition Determinations: “Rembrandt and the Face of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rembrandt and the Face of Jesus... determine that the objects to be included in the exhibition ``Rembrandt and the Face of Jesus,''...

  7. 75 FR 54692 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' ACTION... ''Mir : The Dutch Interiors.'' The reference notice is corrected to accommodate an additional object to... determine that the additional object to be included in the exhibition ``Mir : The Dutch...

  8. 77 FR 15839 - Culturally Significant Objects Imported for Exhibition Determinations: “Joan Miró: the Ladder of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Joan Mir : the Ladder of Escape... determine that the objects to be included in the exhibition ``Joan Mir : the Ladder of Escape,''...

  9. 78 FR 4585 - Culturally Significant Objects Imported for Exhibition Determinations: “Albrecht Dürer: Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Albrecht D rer: Master Drawings... April 15, 2003), I hereby determine that the objects to be included in the exhibition ``Albrecht D...

  10. 76 FR 73759 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Egypt-Art and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Ancient Egypt--Art and Magic: Treasures From the Foundation Gandur pour L'Art, Geneva, Switzerland'' SUMMARY: Notice is hereby given of... included in the exhibition ``Ancient Egypt--Art and Magic: Treasures from the Foundation Gandur pour...

  11. 77 FR 52783 - Culturally Significant Objects Imported for Exhibition Determinations: “Rudolf Nureyev: A Life in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Rudolf Nureyev: A Life in Dance... determine that the objects to be included in the exhibition ``Rudolf Nureyev: A Life in Dance''...

  12. 77 FR 57637 - Culturally Significant Objects Imported for Exhibition Determinations: “City of Gold: Tomb and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``City of Gold: Tomb and Temple in... ``City of Gold: Tomb and Temple in Ancient Cyprus,'' imported from abroad for temporary exhibition...

  13. 77 FR 64373 - Culturally Significant Object Imported for Exhibition Determinations: “Erotic Gold: The Art and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Erotic Gold: The Art and Life of... April 15, 2003), I hereby determine that the object to be included in the exhibition ``Erotic Gold:...

  14. Functional significance of mononuclear phagocyte populations generated through adult hematopoiesis

    PubMed Central

    Gutknecht, Michael F.; Bouton, Amy H.

    2014-01-01

    Tissue homeostasis requires a complete repertoire of functional macrophages in peripheral tissues. Recent evidence indicates that many resident tissue macrophages are seeded during embryonic development and persist through adulthood as a consequence of localized proliferation. Mononuclear phagocytes are also produced during adult hematopoiesis; these cells are then recruited to sites throughout the body, where they function in tissue repair and remodeling, resolution of inflammation, maintenance of homeostasis, and disease progression. The focus of this review is on mononuclear phagocytes that comprise the nonresident monocyte/macrophage populations in the body. Key features of monocyte differentiation are presented, focusing primarily on the developmental hierarchy that is established through this process, the markers used to identify discrete cell populations, and novel, functional attributes of these cells. These features are then explored in the context of the tumor microenvironment, where mononuclear phagocytes exhibit extensive plasticity in phenotype and function. PMID:25225678

  15. 75 FR 45195 - Culturally Significant Objects Imported for Exhibition Determinations: “Literary Lives: Portraits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... States, are of cultural significance. The objects are imported pursuant to loan agreements with the... the McMullen Museum of Art, Boston College, Chestnut Hill, Massachusetts, from on or about September...

  16. 77 FR 59701 - Culturally Significant Objects Imported for Exhibition Determinations: “Florence at the Dawn of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Florence at the Dawn of Renaissance... at the Dawn of Renaissance: Painting and Illumination,'' imported from abroad for...

  17. 77 FR 42790 - Culturally Significant Objects Imported for Exhibition Determinations: “The Last Days of Pompeii...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Last Days of Pompeii: Decadence... ``The Last Days of Pompeii: Decadence, Apocalypse, Resurrection,'' imported from abroad for...

  18. 78 FR 38430 - Culturally Significant Objects Imported for Exhibition; Determinations: “Of Heaven and Earth: 500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Of Heaven and Earth: 500 Years of... Earth: 500 Years of Italian Painting from Glasgow Museums,'' imported from abroad for...

  19. Graphene oxide nanoribbons exhibit significantly greater toxicity than graphene oxide nanoplatelets.

    PubMed

    Chng, Elaine Lay Khim; Chua, Chun Kiang; Pumera, Martin

    2014-09-21

    Graphene oxide (GOs) has emerged in recent years as a versatile nanomaterial, demonstrating tremendous potential for multifunctional biomedical applications. GOs can be prepared by the top-down or bottom-up approach, which leads to a great variability of GOs being produced due to the different procedures and starting carbon sources adopted. This will have an effect on the physiochemical properties of GOs and their resultant toxic behavior. In this study, we examined the cytotoxicity of graphene-oxide nanoribbons (GONRs; ∼310 × 5000 nm) and graphene-oxide nanoplatelets (GONPs; 100 × 100 nm), prepared from the oxidative treatment of multi-walled carbon nanotubes (MWCNTs; ∼100 × 5000 nm) and stacked graphene nanofibers (SGNFs; 100 × 5000 nm), respectively. In vitro assessments revealed that the GONRs exhibited a much stronger cytotoxicity over the GONPs, and we correlated that observation with characterization data that showed GONRs to have a greater amount of carbonyl groups as well as greater length. Therefore, we put forward that the stronger toxic behavior of GONRs is a result of the synergistic effect between these two factors, and the type of carbon source used to prepare GOs should be carefully considered in any future bioapplications.

  20. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... agency under Public Law 103-354 environmental reviewer. After reviewing the assessment and the supporting... environmental laws and requirements listed therein. Insert signature and title of approving official as... 7 Agriculture 13 2012-01-01 2012-01-01 false Finding of No Significant Environmental Impact...

  1. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... agency under Public Law 103-354 environmental reviewer. After reviewing the assessment and the supporting... environmental laws and requirements listed therein. Insert signature and title of approving official as... 7 Agriculture 13 2014-01-01 2013-01-01 true Finding of No Significant Environmental Impact...

  2. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... agency under Public Law 103-354 environmental reviewer. After reviewing the assessment and the supporting... environmental laws and requirements listed therein. Insert signature and title of approving official as... 7 Agriculture 13 2011-01-01 2009-01-01 true Finding of No Significant Environmental Impact...

  3. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... agency under Public Law 103-354 environmental reviewer. After reviewing the assessment and the supporting... environmental laws and requirements listed therein. Insert signature and title of approving official as... 7 Agriculture 13 2010-01-01 2009-01-01 true Finding of No Significant Environmental Impact...

  4. 7 CFR Exhibit I to Subpart G of... - Finding of No Significant Environmental Impact

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... agency under Public Law 103-354 environmental reviewer. After reviewing the assessment and the supporting... environmental laws and requirements listed therein. Insert signature and title of approving official as... 7 Agriculture 13 2013-01-01 2013-01-01 false Finding of No Significant Environmental Impact...

  5. DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs

    PubMed Central

    Cheng, Liang; Jiang, Yue; Wang, Zhenzhen; Shi, Hongbo; Sun, Jie; Yang, Haixiu; Zhang, Shuo; Hu, Yang; Zhou, Meng

    2016-01-01

    The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the similarity between Disease Ontology (DO) terms and provide the significance of the similarity score. Furthermore, DisSim integrated TCs of diseases from the Comparative Toxicogenomics Database (CTD), which can help to identify potential relationships between TCs and similar diseases. The system can be accessed from http://123.59.132.21:8080/DisSim. PMID:27457921

  6. Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits.

    PubMed

    Vinson, Joe A; Cai, Yuxing

    2012-02-01

    Free and total (after basic hydrolysis) polyphenols in nine types of raw and roasted nuts and two types of peanut butter (54 commercial samples) were analyzed after methanol extraction by a single step Folin-Ciocalteu reagent using catechin as standard. Walnuts had the highest free and total polyphenols in both the combined raw and roasted samples. Total polyphenols in the nuts were significantly higher than free polyphenols. Roasting had little effect on either free or total polyphenols in nuts. Raw and roasted walnuts had the highest total polyphenols. The efficacy of raw and roasted nut antioxidants was assessed by measuring the ability of the free polyphenol nut extracts to inhibit the oxidation of lower density lipoproteins (LDL + VLDL). A nut polyphenol, catechin, was measured after binding of three nut extracts to lower density lipoproteins. Walnut polyphenols had the best efficacy among the nuts and also the highest lipoprotein-bound antioxidant activity. Based on USDA availability data, the per capita total polyphenols was 162 mg from nuts per day in 2008. This corresponds to 19% of the total polyphenols from fruits and vegetables, nuts, grains, oils and spices in the US diet. Nuts provided 158 mg of polyphenols per day to the European Union diet. Nuts are high in polyphenol antioxidants which by binding to lipoproteins would inhibit oxidative processes that lead to atherosclerosis in vivo. In human supplementation studies nuts have been shown to improve the lipid profile, increase endothelial function and reduce inflammation, all without causing weight gain. These qualities make nuts a nutritious healthy snack and food additive.

  7. The significance of low back pain in older adults.

    PubMed

    Fernbach, J C; Langer, F; Gross, A E

    1976-11-06

    A retrospective study of the practice of an orthopedic surgeon at a university teaching hospital was done to evaluate the significance of low back pain in older adults. All 259 patients in a 3-year period 50 years of age and over whose presenting complaint was low back pain or sciatica or both were identified and classified by final diagnosis. A comparison was similarly identified and classified. Systemic disease, particularly cancer, was much more prevalent in the older group. It was demonstrated that a simple screening routine consisting of measuring the erythrocyte sedimentation rate and serum concentrations of alkaline phosphatase and calcium would identify all cases of unsuspected malignant disease--that is, at least one of the values would be abnormal in every case.

  8. 78 FR 61981 - Culturally Significant Objects Imported for Exhibition Determinations: “Ink Art: The Past as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ink Art: The Past as Present in... ``Ink Art: The Past as Present in Contemporary China,'' imported from abroad for temporary...

  9. 77 FR 319 - Culturally Significant Objects Imported for Exhibition Determinations: “Put Your Freedom in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Put Your Freedom in the Corner, Save... of Authority No. 257 of April 15, 2003), I hereby determine that the object ``Put Your Freedom in...

  10. Prognotic significance of pretreatment proliferative activity in adult acute leukemia.

    PubMed

    Hart, J S; George, S L; Frei, E; Bodey, G P; Nickerson, R C; Freireich, E J

    1977-04-01

    A statistical analysis of the prognostic significance of eight pretreatment variables was undertaken for 71 previously untreated adult patients with acute leukemia seen at M.D. Anderson Hospital over a 5 1/2-year period. None of the patients had received any prior therapy. Nearly all of the patients (68 of the 71) were treated with 4- or 5-day courses of arabinosyl-cytosine alone or in combination with cyclophosphamide, vincristine (oncovin) and prednisone (COAP). The pretreatment variables studied were age at diagnosis, the percent labeling index of the bone marrow leukemic cells, diagnosis, the highest temperature prior to start of treatment, the marrow clot section cellularity and smear differential percent of blasts, percent absolute marrow leukemic cell infiltrate and absolute number of blasts X 10(3)/mm3 in the peripheral blood. Fifty-one patients had acute myeloblastic leukemia (AML) and 20 patients had acute lymphoblastic leukemia (ALL). Using a statistical regression model approach, the only variables found to be of significant prognostic importance with respect to the probability of complete remission for AML patients were the pretreatment percent labeling index, the age of the patient and the highest temperature prior to start of treatment. Unlike AML, the initial percent labeling index did not appear to be of prognostic significance for ALL patients. AML patients with high labeling indices (larger than or equal to 9%) and young patients in general (especially those less than 40 years old) had the best remission rates. With respect to the length of complete remission and survival for all patients, the only important variables were the pretreatment percent labeling index and the age of the patient, respectively. Once in complete remission, an initially high labeling index was an unfavorable sign with respect to length of remission, regardless of the patient's diagnosis. The results of this study are supportive of studies in experimental systems

  11. Startle response memory and hippocampal changes in adult zebrafish pharmacologically-induced to exhibit anxiety/depression-like behaviors.

    PubMed

    Pittman, Julian T; Lott, Chad S

    2014-01-17

    Zebrafish (Danio rerio) are rapidly becoming a popular animal model for neurobehavioral and psychopharmacological research. While startle testing is a well-established assay to investigate anxiety-like behaviors in different species, screening of the startle response and its habituation in zebrafish is a new direction of translational biomedical research. This study focuses on a novel behavioral protocol to assess a tapping-induced startle response and its habituation in adult zebrafish that have been pharmacologically-induced to exhibit anxiety/depression-like behaviors. We demonstrated that zebrafish exhibit robust learning performance in a task adapted from the mammalian literature, a modified plus maze, and showed that ethanol and fluoxetine impair memory performance in this maze when administered after training at a dose that does not impair motor function, however, leads to significant upregulation of hippocampal serotoninergic neurons. These results suggest that the maze associative learning paradigm has face and construct validity and that zebrafish may become a translationally relevant study species for the analysis of the mechanisms of learning and memory changes associated with psychopharmacological treatment of anxiety/depression.

  12. Diet selection exhibited by juvenile and adult lifestages of the omnivores Western tarnished plant bug, Lygus hesperus and tarnished plant bug, Lygus lineolaris.

    PubMed

    Hagler, James R; Jackson, C Glen; Blackmer, Jacquelyn L

    2010-01-01

    Lygus hesperus Knight and Lygus lineolaris (Palisot de Beauvois) (Heteroptera: Miridae) are economically important plant bugs on many crops worldwide. However, these omnivores are also facultative predators on a wide variety of insects. This study was conducted to quantify and compare herbivory and carnivory exhibited among different lifestages of these two insect pests. The feeding activity of a total of 422 individuals was observed for 1 h each in feeding arenas containing a cotton leaf disk and copious amounts of the sweetpotato whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) eggs, nymphs and adults. The L. hesperus and L. lineolaris lifestages examined included adults and 3rd, 4th and 5th instar nymphs. Plant feeding occupied the majority of both species' time budget, regardless of the species or lifestage examined. There was a tendency for L. lineolaris lifestages to feed more often and for longer duration on plant tissue than L. hesperus. All lifestages of both species rarely fed on B. tabaci, but when they did, they preferred nymphs > adults > eggs. There were only a few cases where there were significant differences in predation rates and prey handling times exhibited among lifestages and between species, but juvenile L. hesperus tended to be more predaceous than juvenile L. lineolaris on whitefly nymphs and adults and 5th instar and adult L. lineolaris were significantly more herbaceous than their L. hesperus counterparts. In addition, the younger individuals of both species tended to have greater prey handling times than their older counterparts. The significance of these findings is discussed.

  13. 75 FR 53730 - Culturally Significant Object Imported for Exhibition Determinations: “The Roman Mosaic from Lod...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... for Exhibition Determinations: ``The Roman Mosaic from Lod, Israel'' SUMMARY: Notice is hereby given... hereby determine that the object to be included in the exhibition ``The Roman Mosaic from Lod, Israel... that the exhibition or display of the exhibit object at the Metropolitan Museum of Art, New York,...

  14. 75 FR 53730 - Culturally Significant Objects Imported for Exhibition Determinations: “Richard Hawkins-Third Mind”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... Imported for Exhibition Determinations: ``Richard Hawkins--Third Mind'' SUMMARY: Notice is hereby given of... determine that the objects to be included in the exhibition ``Richard Hawkins--Third Mind,'' imported...

  15. 75 FR 19668 - Culturally Significant Objects Imported for Exhibition Determinations: “From Xanadu to Dadu: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... Imported for Exhibition Determinations: ``From Xanadu to Dadu: The World of Khubilai Khan'' SUMMARY: Notice... hereby determine that the objects to be included in the exhibition ``From Xanadu to Dadu: The World...

  16. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Heaven and Earth: Art of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... for Exhibition Determinations: ``Heaven and Earth: Art of Byzantium from Greek Collections'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Heaven and Earth: Art...

  17. [Significance of grandparents for young-adult grandchildren].

    PubMed

    Verschueren, K; Van Ranst, N; Marcoen, A

    1993-02-01

    Do young adult grandchildren find their grandparents important? What are the meanings that grandparents seem to have for these grandchildren? Those were the leading questions in the present study. Subjects were 239 university students (mean age: 19.5 years). They completed the Grandparents Meaning Scale, a recently developed 82-item instrument which probes for 11 a priori dimensions of meaning of grandparents for grandchildren: (I) Reliable alliance, (2) Affection and emotional support, (3) Reassurance of worth, (4) Practical and financial support, (5) Link with the past, (6) Acquaintance with aging, (7) Mentor and role-model, (8) Kinkeeper, (9) Mediator between children and parents, (10) Substitute caregiver, and (11) Distant figure. Subjects rated the importance and meaning of 222 grandmothers and 159 grandfathers. The results confirmed earlier findings. Young adult grandchildren generally found their grandparents important. Grandparents were valued because they provide their grandchildren with reassurance of worth and emotional support, and link their lives to the historical past. Grandmothers received higher scores than grandfathers on seven scales (1-4, 8-10). Grandfathers had higher scores on just two of the scales (5 and 11). Gender differences emerged with regard to the ratings of the grandmothers only. Girls had higher scores than boys on eight scales (1-3, 5, 7-10) and boys had a higher score on just one scale (11).

  18. Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.

    PubMed

    Imgrund, Silke; Hartmann, Dieter; Farwanah, Hany; Eckhardt, Matthias; Sandhoff, Roger; Degen, Joachim; Gieselmann, Volkmar; Sandhoff, Konrad; Willecke, Klaus

    2009-11-27

    (Dihydro)ceramide synthase 2 (cers2, formerly called lass2) is the most abundantly expressed member of the ceramide synthase gene family, which includes six isoforms in mice. CERS2 activity has been reported to be specific toward very long fatty acid residues (C22-C24). In order to study the biological role of CERS2, we have inactivated its coding region in transgenic mice using gene-trapped embryonic stem cells that express lacZ reporter DNA under control of the cers2 promoter. The resulting mice lack ceramide synthase activity toward C24:1 in the brain as well as the liver and show only very low activity toward C18:0-C22:0 in liver and reduced activity toward C22:0 residues in the brain. In addition, these mice exhibit strongly reduced levels of ceramide species with very long fatty acid residues (>or=C22) in the liver, kidney, and brain. From early adulthood on, myelin stainability is progressively lost, biochemically accompanied by about 50% loss of compacted myelin and 80% loss of myelin basic protein. Starting around 9 months, both the medullary tree and the internal granular layer of the cerebellum show significant signs of degeneration associated with the formation of microcysts. Predominantly in the peripheral nervous system, we observed vesiculation and multifocal detachment of the inner myelin lamellae in about 20% of the axons. Beyond 7 months, the CERS2-deficient mice developed hepatocarcinomas with local destruction of tissue architecture and discrete gaps in renal parenchyma. Our results indicate that CERS2 activity supports different biological functions: maintenance of myelin, stabilization of the cerebellar as well as renal histological architecture, and protection against hepatocarcinomas.

  19. 76 FR 30751 - Culturally Significant Object Imported for Exhibition Determinations: “Turkish Taste at the Court...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ...-Antoinette'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``Turkish Taste at the Court of Marie- Antoinette,'' imported from abroad for temporary exhibition...

  20. 75 FR 80885 - Culturally Significant Objects Imported for Exhibition Determinations: “Rooms With a View: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... in the 19th Century'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to... the exhibition ``Rooms with a View: The Open Window in the 19th Century,'' imported from abroad for... display of the exhibit objects at the Metropolitan Museum of Art, New York, New York, from on or...

  1. Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning.

    PubMed

    Biane, Jeremy S; Takashima, Yoshio; Scanziani, Massimo; Conner, James M; Tuszynski, Mark H

    2016-03-16

    Layer 5 neurons of the neocortex receive direct and relatively strong input from the thalamus. However, the intralaminar distribution of these inputs and their capacity for plasticity in adult animals are largely unknown. In slices of the primary motor cortex (M1), we simultaneously recorded from pairs of corticospinal neurons associated with control of distinct motor outputs: distal forelimb versus proximal forelimb. Activation of ChR2-expressing thalamocortical afferents in M1 before motor learning produced equivalent responses in monosynaptic excitation of neurons controlling the distal and proximal forelimb, suggesting balanced thalamic input at baseline. Following skilled grasp training, however, thalamocortical input shifted to bias activation of corticospinal neurons associated with control of the distal forelimb. This increase was associated with a cell-specific increase in mEPSC amplitude but not presynaptic release probability. These findings demonstrate distinct and highly segregated plasticity of thalamocortical projections during adult learning.

  2. The fetal/neonatal mouse liver exhibits transcriptional features of the adult pancreas.

    EPA Science Inventory

    Metabolic homeostasis of the organism is maintained by the liver’s ability to detoxify and eliminate xenobiotics through the expression of xenobiotic metabolism enxymes (XME). The fetus and neonate have been hypothesized to exhibit increased sensitivity to xenobiotic toxicity. T...

  3. 77 FR 75253 - Culturally Significant Objects Imported for Exhibition Determinations: “Wait, Later This Will Be...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ...: Editions by Dieter Roth'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... Nothing: Editions by Dieter Roth,'' imported from abroad for temporary exhibition within the United...

  4. 75 FR 53013 - Culturally Significant Objects Imported for Exhibition Determinations: “The Pre-Raphaelite Lens...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Photography and Painting, 1848-1875'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``The Pre-Raphaelite Lens: British Photography and Painting, 1848-1875,'' imported...

  5. 76 FR 6650 - Culturally Significant Objects Imported for Exhibition Determinations: “Splendors of Faith/Scars...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ...: The Arts of the Missions of Northern New Spain, 1600-1821'' SUMMARY: Notice is hereby given of the... exhibition ``Splendors of Faith/Scars of Conquest: The Arts of the Missions of Northern New Spain,...

  6. Zebra finches and Dutch adults exhibit the same cue weighting bias in vowel perception.

    PubMed

    Ohms, Verena R; Escudero, Paola; Lammers, Karin; ten Cate, Carel

    2012-03-01

    Vocal tract resonances, called formants, are the most important parameters in human speech production and perception. They encode linguistic meaning and have been shown to be perceived by a wide range of species. Songbirds are also sensitive to different formant patterns in human speech. They can categorize words differing only in their vowels based on the formant patterns independent of speaker identity in a way comparable to humans. These results indicate that speech perception mechanisms are more similar between songbirds and humans than realized before. One of the major questions regarding formant perception concerns the weighting of different formants in the speech signal ("acoustic cue weighting") and whether this process is unique to humans. Using an operant Go/NoGo design, we trained zebra finches to discriminate syllables, whose vowels differed in their first three formants. When subsequently tested with novel vowels, similar in either their first formant or their second and third formants to the familiar vowels, similarity in the higher formants was weighted much more strongly than similarity in the lower formant. Thus, zebra finches indeed exhibit a cue weighting bias. Interestingly, we also found that Dutch speakers when tested with the same paradigm exhibit the same cue weighting bias. This, together with earlier findings, supports the hypothesis that human speech evolution might have exploited general properties of the vertebrate auditory system.

  7. On the significance of adult play: what does social play tell us about adult horse welfare?

    NASA Astrophysics Data System (ADS)

    Hausberger, Martine; Fureix, Carole; Bourjade, Marie; Wessel-Robert, Sabine; Richard-Yris, Marie-Annick

    2012-04-01

    Play remains a mystery and adult play even more so. More typical of young stages in healthy individuals, it occurs rarely at adult stages but then more often in captive/domestic animals, which can imply spatial, social and/or feeding deprivations or restrictions that are challenging to welfare, than in animals living in natural conditions. Here, we tested the hypothesis that adult play may reflect altered welfare states and chronic stress in horses, in which, as in several species, play rarely occurs at adult stages in natural conditions. We observed the behaviour (in particular, social play) of riding school horses during occasional outings in a paddock and measured several stress indicators when these horses were in their individual home boxes. Our results revealed that (1) the number of horses and rates of adult play appeared very high compared to field report data and (2) most stress indicators measured differed between `players' and `non-players', revealing that most `playful' animals were suffering from more chronic stress than `non-playful' horses. Frequency of play behaviour correlated with a score of chronic stress. This first discovery of a relationship between adult play and altered welfare opens new lines of research that certainly deserves comparative studies in a variety of species.

  8. 75 FR 28095 - Culturally Significant Object Imported for Exhibition Determinations: “E Ku Ana Ka Paia...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ..., Responsibility and the Ku Images'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...: Unification, Responsibility and the Ku Images,'' imported from abroad for temporary exhibition within the... that Public Notice of these Determinations be published in the Federal Register. FOR...

  9. Pelvic Fixation in Adult and Pediatric Spine Surgery: Historical Perspective, Indications, and Techniques: AAOS Exhibit Selection.

    PubMed

    Jain, Amit; Hassanzadeh, Hamid; Strike, Sophia A; Menga, Emmanuel N; Sponseller, Paul D; Kebaish, Khaled M

    2015-09-16

    Achieving solid osseous fusion across the lumbosacral junction has historically been, and continues to be, a challenge in spine surgery. Robust pelvic fixation plays an integral role in achieving this goal. The goals of this review are to describe the history of and indications for spinopelvic fixation, examine conventional spinopelvic fixation techniques, and review the newer S2-alar-iliac technique and its outcomes in adult and pediatric patients with spinal deformity. Since the introduction of Harrington rods in the 1960s, spinal instrumentation has evolved substantially. Indications for spinopelvic fixation as a means to achieve lumbosacral arthrodesis include a long arthrodesis (five or more vertebral levels) or use of three-column osteotomies in the lower thoracic or lumbar spine, surgical treatment of high-grade spondylolisthesis, and correction of lumbar deformity and pelvic obliquity. A variety of techniques have been described over the years, including Galveston iliac rods, Jackson intrasacral rods, the Kostuik transiliac bar, iliac screws, and S2-alar-iliac screws. Modern iliac screws and S2-alar-iliac screws are associated with relatively low rates of pseudarthrosis. S2-alar-iliac screws have the advantages of less implant prominence and inline placement with proximal spinal anchors. Collectively, these techniques provide powerful methods for obtaining control of the pelvis in facilitating lumbosacral arthrodesis.

  10. Adult and hatch-year blackpoll warblers exhibit radically different regional-scale movements during post-fledging dispersal

    PubMed Central

    Taylor, Philip D.

    2015-01-01

    Using a broad-scale automated telemetry array, we explored post-fledging movements of blackpoll warblers breeding in Atlantic Canada. We sought to determine the full spatial scale of post-fledging dispersal, to assess support for three hypotheses for regional-scale post-fledging movement, and to determine whether learning influenced movement during this period. We demonstrated that both young and adults moved over distances more than 200 km prior to initiating migration. Adults moved southwest, crossing the Gulf of Maine (GOM), consistent with the commencement of migration hypothesis. Hatch-year birds exhibited less directional movements constrained geographically by the GOM. Their movements were most consistent with exploration hypotheses—that young birds develop a regional-scale map to aid in habitat selection, natal dispersal and subsequent migrations. PMID:26631243

  11. Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium

    PubMed Central

    Marques, Joana; Vilanova, Eduardo; Mourão, Paulo A. S.; Fernàndez-Busquets, Xavier

    2016-01-01

    The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity. Here, we have explored the antiplasmodial capacity of heparin-like sulfated polysaccharides from the sea cucumbers Ludwigothurea grisea and Isostichopus badionotus, from the red alga Botryocladia occidentalis, and from the marine sponge Desmapsamma anchorata. In vitro experiments demonstrated for most compounds significant inhibition of Plasmodium falciparum growth at low-anticoagulant concentrations. This activity was found to operate through inhibition of erythrocyte invasion by Plasmodium, likely mediated by a coating of the parasite similar to that observed for heparin. In vivo four-day suppressive tests showed that several of the sulfated polysaccharides improved the survival of Plasmodium yoelii-infected mice. In one animal treated with I. badionotus fucan parasitemia was reduced from 10.4% to undetectable levels, and Western blot analysis revealed the presence of antibodies against P. yoelii antigens in its plasma. The retarded invasion mediated by sulfated polysaccharides, and the ensuing prolonged exposure of Plasmodium to the immune system, can be explored for the design of new therapeutic approaches against malaria where heparin-related polysaccharides of low anticoagulating activity could play a dual role as drugs and as potentiators of immune responses. PMID:27071342

  12. Gas-Phase Ambient Air Contaminants Exhibit Significant Dioxin-like and Estrogen-like Activity in Vitro

    PubMed Central

    Klein, Gail P.; Hodge, Erin M.; Diamond, Miriam L.; Yip, Amelia; Dann, Tom; Stern, Gary; Denison, Michael S.; Harper, Patricia A.

    2006-01-01

    Several adverse health effects, such as respiratory and cardiovascular morbidity, have been linked to exposure to particulate matter in ambient air; however, the biologic activity of gas-phase ambient organic air contaminants has not been examined as thoroughly. Using aryl hydrocarbon receptor (AHR)–based and estrogen receptor (ER)–based cell bioassay systems, we assessed the dioxin-like and estrogenic activities of gas-phase organic ambient air contaminants compared with those of particulate-phase contaminants using samples collected between seasons over 2 years from an urban and a rural location in the Greater Toronto Area, Canada. The concentration of the sum (∑) of polycyclic aromatic hydrocarbons, which was highest in the gas phase, was 10–100 times more abundant than that of ∑polychlorinated biphenyls, ∑nitro-polycyclic aromatic hydrocarbons, and ∑organochlorine pesticides, and 103 to 104 times more abundant than ∑polychlorinated dibenzo-p-dioxins/dibenzofurans. Gas-phase samples induced significant AHR- and ER-dependent gene expression. The activity of the gas-phase samples was greater than that of the particulate-phase samples in the estrogen assay and, in one case, in the AHR assay. We found no strong associations between either summer or winter seasons or urban or rural locations in the relative efficacy of the extracts in either the ER or AHR assay despite differences in chemical composition, concentrations, and abundance. Our results suggest that mechanistic studies of the health effects of ambient air must consider gas and particulate phases because chemicals present in both phases can affect AHR and ER signaling pathways. PMID:16675423

  13. The Developmental Significance of Late Adolescent Substance Use for Early Adult Functioning

    ERIC Educational Resources Information Center

    Englund, Michelle M.; Siebenbruner, Jessica; Oliva, Elizabeth M.; Egeland, Byron; Chung, Chu-Ting; Long, Jeffrey D.

    2013-01-01

    This study examines the predictive significance of late adolescent substance use groups (i.e., abstainers, experimental users, at-risk users, and abusers) for early adult adaptation. Participants (N = 159) were drawn from a prospective longitudinal study of first-born children of low-income mothers. At 17.5 years of age, participants were assigned…

  14. Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma in Older Adults.

    PubMed

    Guerard, Emily J; Tuchman, Sascha A

    2016-02-01

    Multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) are plasma cell disorders of aging. The landscape of the diagnosis and management of MM and MGUS are rapidly changing. This article provides an updated understanding of the clinical presentation, evaluation, diagnosis, and management of older adults with MM and MGUS. Because most oncology providers are not formally trained in geriatric medicine, geriatricians play a key role in providing oncologists with a broader understanding of patient health status in the hope of improving outcomes for older adults with MM.

  15. Significance of Anti-HLA Antibodies on Adult and Pediatric Heart Allograft Outcomes

    PubMed Central

    Mangiola, Massimo; Marrari, Marilyn; Feingold, Brian; Zeevi, Adriana

    2017-01-01

    As methods for human leukocyte antigens (HLA) antibody detection have evolved and newer solid phase assays are much more sensitive, the last 15 years has seen a renewed focus on the importance of HLA antibodies in solid organ transplant rejection. However, there is still much controversy regarding the clinical significance of antibody level as depicted by the mean fluorescence intensity of a patient’s neat serum. Emerging techniques, including those that identify antibody level and function, show promise for the detection of individuals at risk of allograft rejection, determination of the effectiveness of desensitization prior to transplant, and for monitoring treatment of rejection. Here, we review current publications regarding the relevance of donor-specific HLA antibodies (DSA) in adult and pediatric heart transplantation (HT) with graft survival, development of antibody-mediated rejection and cardiac allograft vasculopathy (CAV). The negative impact of DSA on patient and allograft survival is evident in adult and pediatric HT recipients. Many questions remain regarding the most appropriate frequency of assessment of pre- and posttransplant DSA as well as the phenotype of DSA memory vs. true de novo antibody using large multicenter adult and pediatric cohorts and state-of-the-art methodologies for DSA detection and characterization. PMID:28191005

  16. Haemodynamic correlates and prognostic significance of serum uric acid in adult patients with Eisenmenger syndrome

    PubMed Central

    Oya, H; Nagaya, N; Satoh, T; Sakamaki, F; Kyotani, S; Fujita, M; Nakanishi, N; Miyatake, K

    2000-01-01

    OBJECTIVE—To assess haemodynamic correlates and prognostic significance of serum uric acid in adult patients with Eisenmenger syndrome.
DESIGN—Retrospective observational study.
SETTING—Tertiary referral centre.
PATIENTS—94 adult patients with Eisenmenger syndrome who were diagnosed between September 1982 and July 1998.
MAIN OUTCOME MEASURES—Serum uric acid was measured in all patients, together with clinical and haemodynamic variables related to mortality.
RESULTS—Serum uric acid was raised in patients with Eisenmenger syndrome compared with age and sex matched control subjects (7.0 v 4.7 mg/dl, p < 0.0001) and increased in proportion to the severity of New York Heart Association functional class. Serum uric acid was positively correlated with mean pulmonary arterial pressure (r = 0.30, p = 0.0052) and total pulmonary resistance index (r = 0.55, p < 0.0001), and negatively correlated with cardiac index (r = −0.50, p < 0.0001). During a mean follow up period of 97 months, 38 patients died of cardiopulmonary causes. Among various clinical, echocardiographic, and laboratory variables, serum uric acid remained predictive in multivariate analysis. Kaplan-Meier survival curves based on median serum uric acid showed that patients with high values had a significantly worse survival rate than those with low values (log-lank test: p = 0.0014 in male patients, p = 0.0034 in female patients).
CONCLUSIONS—Serum uric acid increases in proportion to haemodynamic severity in adult patients with Eisenmenger syndrome and is independently associated with long term mortality.


Keywords: Eisenmenger syndrome; prognosis; uric acid; haemodynamics PMID:10862589

  17. Factors of Significant Impact on Proficiency Levels of Adult ESL Learners within Post-Secondary Education in Puerto Rico

    ERIC Educational Resources Information Center

    Perez, Ramon

    2011-01-01

    This qualitative case study seeks to identify factors that have a significant impact on the second language proficiency levels of adult English as a Second Language (ESL) learners at a four-year university in Puerto Rico. Current data indicate that a significant percentage of adult ESL learners encounter major difficulties within the process of…

  18. Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities

    NASA Astrophysics Data System (ADS)

    Zhan, Guanqun; Qu, Xiaolan; Liu, Junjun; Tong, Qingyi; Zhou, Junfei; Sun, Bin; Yao, Guangmin

    2016-09-01

    Zephycandidine A (1), the first naturally occurring imidazo[1,2-f]phenanthridine alkaloid, was isolated from Zephyranthes candida (Amaryllidaceae). The structure of 1 was elucidated by spectroscopic analyses and NMR calculation, and a plausible biogenetic pathway for zephycandidine A (1) was proposed. Zephycandidine A (1) exhibited significant cytotoxicity against five cancer cell lines with IC50 values ranging from 1.98 to 7.03 μM with selectivity indices as high as 10 when compared to the normal Beas-2B cell. Further studies suggested that zephycandidine A (1) induces apoptosis in leukemia cells by the activation of caspase-3, upregulation of Bax, downregulation of Bcl-2, and degradation of PARP expression. In addition, zephycandidine A (1) showed acetylcholinesterase (AChE) inhibitory activity, and the docking studies of zephycandidine A (1) and galanthamine (2) with AChE revealed that interactions with W286 and Y337 are necessary.

  19. Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities

    PubMed Central

    Zhan, Guanqun; Qu, Xiaolan; Liu, Junjun; Tong, Qingyi; Zhou, Junfei; Sun, Bin; Yao, Guangmin

    2016-01-01

    Zephycandidine A (1), the first naturally occurring imidazo[1,2-f]phenanthridine alkaloid, was isolated from Zephyranthes candida (Amaryllidaceae). The structure of 1 was elucidated by spectroscopic analyses and NMR calculation, and a plausible biogenetic pathway for zephycandidine A (1) was proposed. Zephycandidine A (1) exhibited significant cytotoxicity against five cancer cell lines with IC50 values ranging from 1.98 to 7.03 μM with selectivity indices as high as 10 when compared to the normal Beas-2B cell. Further studies suggested that zephycandidine A (1) induces apoptosis in leukemia cells by the activation of caspase-3, upregulation of Bax, downregulation of Bcl-2, and degradation of PARP expression. In addition, zephycandidine A (1) showed acetylcholinesterase (AChE) inhibitory activity, and the docking studies of zephycandidine A (1) and galanthamine (2) with AChE revealed that interactions with W286 and Y337 are necessary. PMID:27658482

  20. Identifying Adult Dengue Patients at Low Risk for Clinically Significant Bleeding

    PubMed Central

    Wong, Joshua G. X.; Thein, Tun Linn; Leo, Yee-Sin; Pang, Junxiong; Lye, David C.

    2016-01-01

    Background Clinically significant bleeding is important for subsequent optimal case management in dengue patients, but most studies have focused on dengue severity as an outcome. Our study objective was to identify differences in admission parameters between patients who developed clinically significant bleeding and those that did not. We sought to develop a model for discriminating between these patients. Methods We conducted a retrospective study of 4,383 adults aged >18 years who were hospitalized with dengue infection at Tan Tock Seng Hospital, Singapore from 2005 to 2008. Patients were divided into those with clinically significant bleeding (n = 188), and those without (n = 4,195). Demographic, clinical, and laboratory variables on admission were compared between groups to determine factors associated with clinically significant bleeding during hospitalization. Results On admission, female gender (p<0.001); temperature >38°C (p<0.001); nausea/vomiting (p = 0.009) and abdominal pain/tenderness (p = 0.005); lower systolic blood pressure (p<0.001); higher pulse rate (p<0.001); increased absolute neutrophil count (ANC; p<0.001); reduced absolute lymphocyte count (ALC; p<0.001), haematocrit percentage (p<0.001) and platelet count (p = 0.04), and increased prothrombin time (p = 0.003) were significantly associated with clinically significant bleeding on univariate analysis. Multivariate analysis showed that independent variables in the final model were female gender (aOR 2.85; 95% CI: 1.9–4.33); temperature >38°C (aOR 1.81; 95% CI: 1.27–2.61), nausea/vomiting (aOR 1.39; 95% CI: 0.94–2.12), ANC (aOR 1.3; 95% CI: 1.15–1.46), ALC (aOR 0.4; 95% CI: 0.25–0.64), hematocrit percentage (aOR 0.96; 95% CI: 0.92–1.002) and platelet count (aOR 0.993; 95% CI: 0.988–0.998). At the cutoff of -3.919, the model achieved an AUC of 0.758 (sensitivity:0.87, specificity: 0.38, PPV: 0.06, NPV: 0.98). Conclusion Clinical risk factors associated with clinically significant

  1. Dietary Mannoheptulose Does Not Significantly Alter Daily Energy Expenditure in Adult Labrador Retrievers

    PubMed Central

    McKnight, Leslie L.; Root-McCaig, Jared; Wright, David; Davenport, Gary M.; France, James; Shoveller, Anna Kate

    2015-01-01

    Mannoheptulose (MH), a sugar found in avocados that inhibits glycolysis in vitro, has been preliminarily investigated as a novel food ingredient for dogs. This study aimed to determine the effects of dietary MH, delivered as an extract of un-ripened avocado, on energy expenditure (EE) in healthy adult Labrador Retriever dogs (total of 12 dogs, 26.99 ± 0.634 kg, 4.9 ± 0.2 y). The study was a double-blind, cross-over with each dog receiving both dietary treatments, control (CON) and MH (400 mg/kg of diet; 6 mg/kg BW), in random order. Resting and post-prandial (10 h) EE and respiratory quotient (RQ) were determined by indirect calorimetry (d 42). The following day, body composition was assessed using dual X-ray absorptiometry. Continuous activity monitoring was conducted using an Atical® accelerometer (d 43–47). A vastus lateralis muscle biopsy was obtained prior to the morning meal (d 49) and 4 h after consumption of their meal (d 56) to determine the protein content and phosphorylation of 5' adenosine monophosphate-activated protein kinase (AMPK). Diet did not affect body weight, resting EE or skeletal muscle AMPK phosphorylation. Dogs fed MH had significantly lower post-prandial RQ (p = 0.02) and ratio of fat to lean body mass (p = 0.02). Physical activity during light time periods (but not dark) was lower in dogs fed MH (p < 0.05) during weekends, but not on weekdays. These results suggest that MH affects energy balance of adult dogs, but that these effects are not dose dependent and not due to physical activity. PMID:26656105

  2. Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults

    PubMed Central

    Titlow, Joshua S.; Davis, Ilan; Barker, Amy R.; Dawe, Helen R.

    2016-01-01

    ABSTRACT Cilia are conserved organelles that have important motility, sensory and signalling roles. The transition zone (TZ) at the base of the cilium is crucial for cilia function, and defects in several TZ proteins are associated with human congenital ciliopathies such as nephronophthisis (NPHP) and Meckel–Gruber syndrome (MKS). In several species, MKS and NPHP proteins form separate complexes that cooperate with Cep290 to assemble the TZ, but flies seem to lack core components of the NPHP module. We show that MKS proteins in flies are spatially separated from Cep290 at the TZ, and that flies mutant for individual MKS genes fail to recruit other MKS proteins to the TZ, whereas Cep290 seems to be recruited normally. Although there are abnormalities in microtubule and membrane organisation in developing MKS mutant cilia, these defects are less apparent in adults, where sensory cilia and sperm flagella seem to function quite normally. Thus, localising MKS proteins to the cilium or flagellum is not essential for viability or fertility in flies. PMID:27577095

  3. Preschool-age children and adults flexibly shift their preferences for auditory versus visual modalities but do not exhibit auditory dominance.

    PubMed

    Noles, Nicholaus S; Gelman, Susan A

    2012-07-01

    The goal of this study was to evaluate the claim that young children display preferences for auditory stimuli over visual stimuli. This study was motivated by concerns that the visual stimuli employed in prior studies were considerably more complex and less distinctive than the competing auditory stimuli, resulting in an illusory preference for auditory cues. Across three experiments, preschool-age children and adults were trained to use paired audio-visual cues to predict the location of a target. At test, the cues were switched so that auditory cues indicated one location and visual cues indicated the opposite location. In contrast to prior studies, preschool-age children did not exhibit auditory dominance. Instead, children and adults flexibly shifted their preferences as a function of the degree of contrast within each modality, with high contrast leading to greater use.

  4. Women as Learners: The Significance of Gender in Adult Learning. The Jossey-Bass Higher and Adult Education Series.

    ERIC Educational Resources Information Center

    Hayes, Elisabeth; Flannery, Daniele D.

    This book is intended to address the need for information and understanding about adult women's learning and education. It gathers knowledge about women and their learning and places women's learning experiences in the contexts of where women live. The book also promotes an understanding of women's diversity and makes recommendations for future…

  5. Appendicular Fractures: A Significant Problem among Institutionalized Adults with Developmental Disabilities.

    ERIC Educational Resources Information Center

    Ryder, K. M.; Williams, J.; Womack, C.; Nayak, N. G.; Nasef, S.; Bush, A.; Tylavsky, F. A.; Carbone, L.

    2003-01-01

    This study found a high incidence of nontraumatic fractures in adults with developmental disabilities living in a state-run facility, a 7.3% incidence among 391 adults. Factors associated with fractures included use of antiepileptic medication. Although bone mineral density (BMD) by heel ultrasound did not predict fracture, values were much lower…

  6. Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

    PubMed Central

    2013-01-01

    Background Activating mutations [internal tandem duplication (ITD)] or overexpression of the FMS-like tyrosine kinase receptor-3 (FLT3) gene are associated with poor outcome in acute myeloid leukemia (AML) patients, underscoring the need for novel therapeutic approaches. The natural product silvestrol has potent antitumor activity in several malignancies, but its therapeutic impact on distinct molecular high-risk AML subsets remains to be fully investigated. We examined here the preclinical activity of silvestrol in FLT3-ITD and FLT3 wild-type (wt) AML. Methods Silvestrol in vitro anti-leukemic activity was examined by colorimetric cell viability assay, colony-forming and flow cytometry assays assessing growth inhibition and apoptosis, respectively. Pharmacological activity of silvestrol on FLT3 mRNA translation, mRNA and protein expression was determined by RNA-immunoprecipitation, qRT-PCR and immunoblot analyses, respectively. Silvestrol in vivo efficacy was investigated using MV4-11 leukemia-engrafted mice. Results Silvestrol shows antileukemia activity at nanomolar concentrations both in FLT3-wt overexpressing (THP-1) and FLT3-ITD (MV4-11) expressing AML cell lines (IC50 = 3.8 and 2.7 nM, respectively) and patients’ primary blasts [IC50 = ~12 nM (FLT3-wt) and ~5 nM (FLT3-ITD)]. Silvestrol increased apoptosis (~4fold, P = 0.0001), and inhibited colony-formation (100%, P < 0.0001) in primary blasts. Silvestrol efficiently inhibited FLT3 translation reducing FLT3 protein expression by 80–90% and decreased miR-155 levels (~60%), a frequently co-regulated onco-miR in FLT3-ITD-positive AML. The median survival of silvestrol-treated vs vehicle-treated mice was 63 vs 29 days post-engraftment, respectively (P < 0.0001). Conclusions Silvestrol exhibits significant in vivo and in vitro antileukemic activities in AML through a novel mechanism resulting in inhibition of FLT3 and miR-155 expression. These encouraging results warrant a rapid

  7. Children's Drawings of Significant Figures for a Peer or an Adult Audience

    ERIC Educational Resources Information Center

    Burkitt, Esther; Watling, Dawn; Murray, Lucy

    2011-01-01

    The present study assessed if children would present different information in their drawings of emotion eliciting stimuli when they believed that an adult or a child audience would view their drawings. Seventy-five 6-year-olds (44 boys and 31 girls) were allocated to three groups: the reference group, the child audience group and the adult…

  8. Adult skin-derived precursor Schwann cells exhibit superior myelination and regeneration supportive properties compared to chronically denervated nerve-derived Schwann cells.

    PubMed

    Kumar, Ranjan; Sinha, Sarthak; Hagner, Andrew; Stykel, Morgan; Raharjo, Eko; Singh, Karun K; Midha, Rajiv; Biernaskie, Jeff

    2016-04-01

    Functional outcomes following delayed peripheral nerve repair are poor. Schwann cells (SCs) play key roles in supporting axonal regeneration and remyelination following nerve injury, thus understanding the impact of chronic denervation on SC function is critical toward developing therapies to enhance regeneration. To improve our understanding of SC function following acute versus chronic-denervation, we performed functional assays of SCs from adult rodent sciatic nerve with acute- (Day 5 post) or chronic-denervation (Day 56 post), versus embryonic nerves. We also compared Schwann cells derived from adult skin-derived precursors (aSKP-SCs) as an accessible, autologous alternative to supplement the distal (denervated) nerve. We found that acutely-injured SCs and aSKP-SCs exhibited superior proliferative capacity, promotion of neurite outgrowth and myelination of axons, both in vitro and following transplant into a sciatic nerve crush injury model, while chronically-denervated SCs were severely impaired. Acute injury caused re-activation of transcription factors associated with an immature and pro-myelinating SC state (Oct-6, cJun, Sox2, AP2α, cadherin-19), but was diminished with prolonged denervation in vivo and could not be rescued following expansion in vitro suggesting that this is a permanent deficiency. Interestingly, aSKP-SCs closely resembled acutely injured and embryonic SCs, exhibiting elevated expression of these same transcription factors. In summary, prolonged denervation resulted in SC deficiency in several functional parameters that may contribute to impaired regeneration. In contrast, aSKP-SCs closely resemble the regenerative attributes ascribed to acutely-denervated or embryonic SCs emphasizing their potential as an accessible and autologous source of glia cells to enhance nerve regeneration, particularly following delays to surgical repair.

  9. Disease screening of three breeding populations of adult exhibition budgerigars (Melopsittacus undulatus) in New Zealand reveals a high prevalence of a novel polyomavirus and avian malaria infection.

    PubMed

    Baron, Hamish R; Howe, Laryssa; Varsani, Arvind; Doneley, Robert J T

    2014-03-01

    Disease surveillance is vital to the management of New Zealand's endemic and threatened avian species. Three infectious agents that are potential threats to New Zealand's endemic birds include avian polyomavirus (APV), beak and feather disease virus (BFDV), and avian malaria. All three agents have been reported in New Zealand; however, possible reservoir populations have not been identified. In this communication, we report the first study of APV, BFDV, and avian malaria in introduced adult exhibition budgerigars (Melopsittacus undulatus) in New Zealand. Blood samples were collected from 90 living adult budgerigars from three breeding locations in the North Island of New Zealand. An overall APV prevalence of 22% was determined using a broad-spectrum nested PCR that amplified the major capsid protein VP1 gene of polyomavirus. Phylogenetic analysis of the VP1 gene revealed a unique isolate of APV, which had a sequence divergence of 32% to previously reported budgerigar fledgling disease strains and 33% to the recently reported New Zealand finch isolate. All of the budgerigars sampled were found to be PCR negative for BFDV, and an overall prevalence of 30% was detected by PCR for avian malaria. Sequencing revealed the presence of ubiquitous malarial strains and also the potentially destructive Plasmodium relictum strain. The results of this study suggest that both APV and avian malaria are present in New Zealand adult budgerigars, and our study highlights the need for further studies to determine whether these pathogens in captive bird populations may be a threat or spill over into New Zealand's endemic and threatened avifauna and whether prevention and control methods need to be implemented.

  10. MIO-M1 cells and similar muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics.

    PubMed

    Lawrence, Jean M; Singhal, Shweta; Bhatia, Bhairavi; Keegan, David J; Reh, Thomas A; Luthert, Philip J; Khaw, Peng T; Limb, Gloria Astrid

    2007-08-01

    Growing evidence suggests that glial cells may have a role as neural precursors in the adult central nervous system. Although it has been shown that Müller cells exhibit progenitor characteristics in the postnatal chick and rat retinae, their progenitor-like role in developed human retina is unknown. We first reported the Müller glial characteristics of the spontaneously immortalized human cell line MIO-M1, but recently we have derived similar cell lines from the neural retina of several adult eye donors. Since immortalization is one of the main properties of stem cells, we investigated whether these cells expressed stem cell markers. Cells were grown as adherent monolayers, responded to epidermal growth factor, and could be expanded indefinitely without growth factors under normal culture conditions. They could be frozen and thawed without losing their characteristics. In the presence of extracellular matrix and fibroblast growth factor-2 or retinoic acid, they acquired neural morphology, formed neurospheres, and expressed neural stem cell markers including betaIII tubulin, Sox2, Pax6, Chx10, and Notch 1. They also expressed markers of postmitotic retinal neurons, including peripherin, recoverin, calretinin, S-opsin, and Brn3. When grafted into the subretinal space of dystrophic Royal College of Surgeons rats or neonatal Lister hooded rats, immortalized cells migrated into the retina, where they expressed various markers of retinal neurons. These observations indicate that adult human neural retina harbors a population of cells that express both Müller glial and stem cell markers and suggest that these cells may have potential use for cell-based therapies to restore retinal function. Disclosure of potential conflicts of interest is found at the end of this article.

  11. Wnt5a Exhibits Layer-Specific Expression in Adult Skin, Is Upregulated in Psoriasis, and Synergizes with Type 1 Interferon

    PubMed Central

    Romanowska, Malgorzata; Evans, Alan; Kellock, David; Bray, Susan E.; McLean, Kathleen; Donandt, Susanne; Foerster, John

    2009-01-01

    Background Wnt5a is a member of the wingless-type patterning regulators important in pre-natal development. The expression and distribution of Wnt5a and its receptors frizzled (fzd) 3 and fzd 5 in adult human skin have not been comprehensively studied to date. Methodology/Principal Findings We here show that Wnt5a, fzd3, fzd5, as well as fzd6 are restricted to specific layers in normal epidermis, analogous to their zonal distribution in hair follicles, suggesting a role in adult skin differentiation. In line, Wnt5a and fzd5 are both overexpressed and re-distributed in the epidermis of psoriasis which involves disturbed keratinocyte differentiation. Functionally, Wnt5a lowers the concentration of IFN required to induce target genes, and increases the magnitude of IFN target gene induction, suggesting a molecular mechanism underlying IFN hypersensitivity in psoriasis. Finally, we identify nedd8 and the amyloid precursor APP, previously shown to be upregulated in psoriasis, as targets of synergistic IFNα/Wnt5a induction. Conclusions/Significance The present data (i) suggest that Wnt5a regulates epidermal differentiation even in adult skin and (ii) identify synergistic induction of type 1 IFN target genes as a novel mode of Wnt5a action. Targeting Wnt5a in the skin may reduce IFN hypersensitivity and be of therapeutical value. PMID:19399181

  12. Moderate drinking? Alcohol consumption significantly decreases neurogenesis in the adult hippocampus.

    PubMed

    Anderson, M L; Nokia, M S; Govindaraju, K P; Shors, T J

    2012-11-08

    Drinking alcohol in moderation is often considered a health-conscious behavior, associated with improved cardiovascular and brain health. However, "moderate" amounts of alcohol include drinking 3-4 alcohol beverages in a day, which is closer to binge drinking and may do more harm than good. Here we examined how daily drinking of moderate-high alcohol alters the production of new neurons in the adult hippocampus. Male and female adult Sprague-Dawley rats were provided free access to a liquid replacement diet that was supplemented with either 4% ethanol or Maltodextrin for a period of 2 weeks. Proliferating cells were labeled with 5-bromo-2-deoxyuridine (BrdU) and the number of BrdU-positive cells in the hippocampus was assessed after the final day of drinking. A subset of rats was also exposed to a motor skill or associative learning task to examine the functional effects of alcohol consumption. The drinking regime resulted in an average blood alcohol concentration of approximately 0.08%, which is comparable to the human legal driving limit in many countries. This level of intoxication did not impair motor skill learning or function in either sex, nor did the alcohol consumption disrupt associative learning 2 days after drinking. Therefore, moderate alcohol consumption did not disrupt basic sensory, motor or learning processes. However, the number of cells produced in the dentate gyrus of the hippocampus was reduced by nearly 40%. Thus, even moderate consumption of alcohol for a relatively short period of time can have profound effects on structural plasticity in the adult brain.

  13. Moderate drinking? Alcohol consumption significantly decreases neurogenesis in the adult hippocampus

    PubMed Central

    Anderson, Megan L.; Nokia, Miriam S.; Govindaraju, Krishna P.; Shors, Tracey J.

    2015-01-01

    Drinking alcohol in moderation is often considered a health-conscious behavior, associated with improved cardiovascular and brain health. However, “moderate” amounts of alcohol include drinking 3-4 alcohol beverages in a day, which is closer to binge drinking and may do more harm than good. Here we examined how daily drinking of moderate-high alcohol alters the production of new neurons in the adult hippocampus. Male and female adult Sprague-Dawley rats were provided free access to a liquid replacement diet that was supplemented with either 4 % ethanol or Maltodextrin for a period of two weeks. Proliferating cells were labeled with 5-bromo-2-deoxyuridine (BrdU) and the number of BrdU-positive cells in the hippocampus was assessed after the final day of drinking. A subset of rats was also exposed to a motor skill or associative learning task to examine the functional effects of alcohol consumption. The drinking regime resulted in an average blood alcohol concentration of approximately 0.08 %, which is comparable to the human legal driving limit in many countries. This level of intoxication did not impair motor skill learning or function in either sex, nor did the alcohol consumption disrupt associative learning two days after drinking. Therefore, moderate alcohol consumption did not disrupt basic sensory, motor or learning processes. However, the number of cells produced in the dentate gyrus of the hippocampus was reduced by nearly 40 %. Thus, even moderate consumption of alcohol for a relatively short period of time can have profound effects on structural plasticity in the adult brain. PMID:22906480

  14. Concise Review: Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration.

    PubMed

    Rumman, Mohammad; Dhawan, Jyotsna; Kassem, Moustapha

    2015-10-01

    Adult stem cells (ASCs) are tissue resident stem cells responsible for tissue homeostasis and regeneration following injury. In uninjured tissues, ASCs exist in a nonproliferating, reversibly cell cycle-arrested state known as quiescence or G0. A key function of the quiescent state is to preserve stemness in ASCs by preventing precocious differentiation, and thus maintaining a pool of undifferentiated ASCs. Recent evidences suggest that quiescence is an actively maintained state and that excessive or defective quiescence may lead to compromised tissue regeneration or tumorigenesis. The aim of this review is to provide an update regarding the biological mechanisms of ASC quiescence and their role in tissue regeneration.

  15. Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance.

    PubMed

    Michelena, Hector I; Della Corte, Alessandro; Prakash, Siddharth K; Milewicz, Dianna M; Evangelista, Artur; Enriquez-Sarano, Maurice

    2015-12-15

    Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

  16. Exhibiting Lives

    ERIC Educational Resources Information Center

    Golden, Deborah; Elbaz-Luwisch, Freema

    2007-01-01

    This paper examines some of the dilemmas that accompany the emergence of the personal voice in scholarly work, by taking a close, grounded look at the way in which these unfolded in a specific academic course. As part of the course, entitled "A cultural approach to the life cycle", students were asked to participate in a group exhibition in which…

  17. Malignant progressive tumor cell clone exhibits significant up-regulation of cofilin-2 and 27-kDa modified form of cofilin-1 compared to regressive clone.

    PubMed

    Kuramitsu, Yasuhiro; Wang, Yufeng; Okada, Futoshi; Baron, Byron; Tokuda, Kazuhiro; Kitagawa, Takao; Akada, Junko; Nakamura, Kazuyuki

    2013-09-01

    QR-32 is a regressive murine fibrosarcoma cell clone which cannot grow when they are transplanted in mice; QRsP-11 is a progressive malignant tumor cell clone derived from QR-32 which shows strong tumorigenicity. A recent study showed there to be differentially expressed up-regulated and down-regulated proteins in these cells, which were identified by proteomic differential display analyses by using two-dimensional gel electrophoresis and mass spectrometry. Cofilins are small proteins of less than 20 kDa. Their function is the regulation of actin assembly. Cofilin-1 is a small ubiquitous protein, and regulates actin dynamics by means of binding to actin filaments. Cofilin-1 plays roles in cell migration, proliferation and phagocytosis. Cofilin-2 is also a small protein, but it is mainly expressed in skeletal and cardiac muscles. There are many reports showing the positive correlation between the level of cofilin-1 and cancer progression. We have also reported an increased expression of cofilin-1 in pancreatic cancer tissues compared to adjacent paired normal tissues. On the other hand, cofilin-2 was significantly less expressed in pancreatic cancer tissues. Therefore, the present study investigated the comparison of the levels of cofilin-1 and cofilin-2 in regressive QR-32 and progressive QRsP-11cells by western blotting. Cofilin-2 was significantly up-regulated in QRsP-11 compared to QR-32 cells (p<0.001). On the other hand, the difference of the intensities of the bands of cofilin-1 (18 kDa) in QR-32 and QRsP-11 was not significant. However, bands of 27 kDa showed a quite different intensity between QR-32 and QRsP-11, with much higher intensities in QRsP-11 compared to QR-32 (p<0.001). These results suggested that the 27-kDa protein recognized by the antibody against cofilin-1 is a possible biomarker for progressive tumor cells.

  18. Etiologic significance of enlargement of the left atrial appendage in adults

    SciTech Connect

    Green, C.E.; Kelley, M.J.; Higgins, C.B.

    1982-01-01

    Fifty-one patients were divided into two groups: 20 patients with proven rheumatic mitral valve disease (RMVD) and 31 patients with left atrial enlargement (LAE) of a nonrheumatic etiology. The latter group included patients with ischemic papillary muscle dysfunction, mitral valve prolapse, and congestive cardiomyopathy. Radiographic studies showed that enlargement of the left atrial appendage (LAAE) was present in 18 of 20 rheumatics but in only one of 31 nonrheumatics. There was no direct relationship between enlargement of the LAA and radiographic or echocardiographic left atrial size, degree of pulmonary venous hypertension (PVH), or presence of atrial fibrillation. It is postulated that rheumatic influammation of the LAA allows it to dilate out of proportion to the body of the left atrium. In the adult patient with radiographic findings of PVH, LAAE is a valuable and specific radiographic sign of rheumatic mitral valve disease.

  19. Museum Exhibit

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A TSP from NASA Tech Briefs provided the solution to an electrical problem at a Florida museum. When a model train would not start without a jerk, a Marshall Space Flight Center development called pulse width control was adapted. The new circuit enables the train to start smoothly and reduces construction and maintenance costs. The same technology is also used in another hands-on exhibit. Applications of other TSPs are anticipated.

  20. Clinical spectrum associated with MOG autoimmunity in adults: significance of sharing rodent MOG epitopes.

    PubMed

    Sepúlveda, Maria; Armangue, Thaís; Martinez-Hernandez, Eugenia; Arrambide, Georgina; Sola-Valls, Nuria; Sabater, Lidia; Téllez, Nieves; Midaglia, Luciana; Ariño, Helena; Peschl, Patrick; Reindl, Markus; Rovira, Alex; Montalban, Xavier; Blanco, Yolanda; Dalmau, Josep; Graus, Francesc; Saiz, Albert

    2016-07-01

    The aim of this study was to report the clinical spectrum associated with antibodies to myelin oligodendrocyte glycoprotein (MOG) in adult patients, and to assess whether phenotypic variants are dependent on recognition of rodent MOG epitopes. We retrospectively analyzed the features, course and outcome of 56 patients whose samples were investigated by brain tissue immunohistochemistry and cell-based assays using human and rodent MOG. The median age at symptom onset was 37 years (range 18-70); 35 patients (63 %) were female. After a median follow-up of 43 months (range 4-554), only 14 patients (25 %) developed a neuromyelitis optica spectrum disorder (NMOSD), 27 patients (47 %) retained the initial diagnosis of isolated optic neuritis, 7 (12 %) of longitudinally extensive transverse myelitis, and 2 (4 %) of acute disseminated encephalomyelitis; 6 patients (11 %) developed atypical demyelinating syndromes (4 had relapsing episodes of short myelitis lesions which in one occurred with optic neuritis; 1 had relapsing brainstem symptoms, and 1 relapsing demyelinating encephalomyelitis). The course was frequently associated with relapses (71 %) and good outcome. Twenty-seven patients (49 %) had antibodies that recognized rodent MOG epitopes, and 9 of them (16 %) showed a myelin staining pattern in rodent tissue. Only the myelin staining pattern was linked to NMOSD (p = 0.005). In conclusion, MOG autoimmunity in adult patients associates with a clinical spectrum wider than the one expected for patients with suspected NMOSD and overall good outcome. Antibodies to rodent MOG epitopes do not associate with any phenotypic variant.

  1. Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

    PubMed Central

    2014-01-01

    Background Children with Idiopathic Short Stature do not attain a normal adult height. The improvement of adult height with treatment with recombinant human growth hormone (rhGH), at doses of 0.16 to 0.28 mg/kg/week is modest, usually less that 4 cm, and they remain short as adults. The benefit obtained seems dose dependent and benefits of 7.0 to 8.0 cm have been reported with higher doses of 0.32 to 0.4 mg/kg/week, but the number of studies is limited. The topic has remained controversial. Objective The objective was to conduct a retrospective analysis of our experience with 123 children with ISS treated with 0.32 ± 0.03 mg/kg/week of rhGH, with the aim of comparing the different subgroups of non-familial short stature, familial short stature, normal puberty, and delayed puberty and to assess the benefit by comparison with 305 untreated historical controls, from nine different randomized and nonrandomized controlled studies. Results Eighty eight of our children (68 males and 20 females) attained an adult height or near adult height of -0.71 SDS (0.74 SD) (95% CI, -0.87 to -0.55) with a benefit over untreated controls of 9.5 cm (7.4 to 11.6 cm) for males and 8.6 cm (6.7 to 10.5 cm) for females. In the analysis of the subgroups, the adult height and adult height gain of children with non-familial short stature were significantly higher than of familial short stature. No difference was found in the cohorts with normal or delayed puberty in any of the subgroups, except between the non-familial short stature and familial short stature puberty cohorts. This has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known. The treatment was safe. There were no significant adverse events. The IGF-1 values were essentially within the levels expected for the stages of puberty. Conclusion Our experience was quite positive with normalization of

  2. Inactivation of fibroblast growth factor receptor signaling in myelinating glial cells results in significant loss of adult spiral ganglion neurons accompanied by age-related hearing impairment.

    PubMed

    Wang, S J; Furusho, M; D'Sa, C; Kuwada, S; Conti, L; Morest, D K; Bansal, R

    2009-11-15

    Hearing loss has been attributed to many factors, including degeneration of sensory neurons in the auditory pathway and demyelination along the cochlear nerve. Fibroblast growth factors (FGFs), which signal through four receptors (Fgfrs), are produced by auditory neurons and play a key role in embryonic development of the cochlea and in neuroprotection against sound-induced injury. However, the role of FGF signaling in the maintenance of normal auditory function in adult and aging mice remains to be elucidated. Furthermore, the contribution of glial cells, which myelinate the cochlear nerves, is poorly understood. To address these questions, we generated transgenic mice in which Fgfr1 and Fgfr2 were specifically inactivated in Schwann cells and oligodendrocytes but not in neurons. Adult mutant mice exhibited late onset of hearing impairment, which progressed markedly with age. The hearing impairment was accompanied by significant loss of myelinated spiral ganglion neurons. The pathology extended into the cochlear nucleus, without apparent loss of myelin or of the deletion-bearing glial cells themselves. This suggests that perturbation of FGF receptor-mediated glial function leads to the attenuation of glial support of neurons, leading to their loss and impairment of auditory functions. Thus, FGF/FGF receptor signaling provides a potentially novel mechanism of maintaining reciprocal interactions between neurons and glia in adult and aging animals. Dysfunction of glial cells and FGF receptor signaling may therefore be implicated in neurodegenerative hearing loss associated with normal aging.

  3. Outdoor Exhibits

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The National Data Buoy Center (NDBC) at the John C. Stennis Space Center has exhibits located in front of the Visitors Center. These boat-shaped buoys are moored in areas of the ocean that experience hostile environmental conditions. The instruments installed gather information and relay it to the National Weather Service by satellite. Nomad buoys are 20 feet long and weigh 13,900 pounds. They provide information on wind speed and direction, humidity levels, air and sea surface temperature and air pressure. U.S. Coast Guard ships transport buoys to their mooring sites.

  4. Analysis of the Distribution of Mucins in Adult Human Gastric Mucosa and Its Functional Significance

    PubMed Central

    2016-01-01

    Introduction Mucins are complex composition of carbohydrates seen in the epithelial cells lining the gastrointestinal tract (GIT). Normal distribution of such mucins in different part of the GIT and its alteration in various inflammatory, benign and malignant lesions of GIT has aroused interest in the field of histochemistry. Aim By applying variety of histochemical techniques an attempt has been made to draw a map of mucin secretion by the different epithelial cell types in different parts of the stomach. Materials and Methods Fifty samples were taken each from different parts of the stomach like fundus, body and pylorus, from dissected fresh specimens (total of 150 specimens). Tissue samples were subjected for routine process and studied for histological and different histochemical staining. Results Mucin pattern in adult predominantly secretes neutral mucosubstances. Surface epithelium shows predominant neutral mucin while cardiac and gastric glands with foveolar cells show moderate amount. Sialomucin is present in a few cells of the surface epithelium, foveolar cells and in most of the mucous neck cells. Small amount of sialomucin and sulphomucin are found in surface epithelial foveolar cells while traces of sulphomucin are found in deep foveolar cells. Mucous neck cells secrete both sulphomucin and sialomucin. Conclusion Normal gastric mucosa adjacent to gastric ulcers and malignant tumours of stomach secretes mucins which differ histochemically and biochemically from that of normal. Early recognition of such changes could be useful in recognizing the different type of carcinomas and their prognosis. PMID:27042436

  5. Night eating syndrome in young adults: delineation from other eating disorders and clinical significance.

    PubMed

    Fischer, Sophia; Meyer, Andrea H; Hermann, Ernst; Tuch, Alex; Munsch, Simone

    2012-12-30

    The Night Eating Syndrome (NES) is a recently described disordered eating style whose status in current diagnostic systems needs to be further clarified. The aim of this study was to increase knowledge about the clinical features of NES in a sample of 1514 young adults aged 18-26 years from the general population who participated in an anonymous Internet survey. We first examined characteristics of NES and tried to delineate it from healthy controls as well as from other eating disorders in terms of socio-demography, eating disorder pathology and general psychopathology. Second, we attempted to further clarify the clinical utility of the NES by assessing the degree of distress as well as impairment. Twenty (1.3%) participants with NES were identified and there was only modest overlap between NES and both Binge Eating Disorder (BED) and Bulimia nervosa (BN) according to questionnaire-based DSM-IV criteria. Compared to healthy controls, NES individuals reported more pronounced eating disorder pathology as well as general psychopathology (depressive symptoms, chronic social stress). NES seems to be associated with considerable distress and impairment. Implications for the validity and classification of NES are discussed.

  6. Adolescents in Institutional Care: Significant Adults, Resilience and Well-Being

    ERIC Educational Resources Information Center

    Mota, Catarina Pinheiro; Matos, Paula Mena

    2015-01-01

    Background: Attachment theory states the importance of secure relationships with significant figures for the development of resilience and well-being. The institutional care context represents a particular environment where relationships beyond the family should be attended for. Objective: The purpose of this study was to analyse the relationship…

  7. The Significance of Prolonged and Saddleback Fever in Hospitalised Adult Dengue

    PubMed Central

    Thein, Tun-Linn; Leo, Yee-Sin; Lye, David C.

    2016-01-01

    Dengue fever is gaining importance in Singapore with an increase in the number of cases and mortality in recent years. Although prolonged and saddleback fever have been reported in dengue fever, there are no specific studies on their significance in dengue. This study aims to examine the prevalence of prolonged and saddleback fever in dengue as well as their associations with dengue severity. A total of 2843 polymerase-chain reaction (PCR) confirmed dengue patients admitted to Tan Tock Seng Hospital from 2004 to 2008 were included in the study. Sixty-nine percent of them were male with a median age of 34 years. Prolonged fever (fever > 7 days duration) was present in 572 (20.1%) of patients. Dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS) and severe dengue (SD) were significantly more likely to occur in patients with prolonged fever. Mucosal bleeding, anorexia, diarrhea, abdominal pain, nausea or vomiting, lethargy, rash, clinical fluid accumulation, hepatomegaly, nosocomial infection, leukopenia, higher neutrophil count, higher hematocrit, higher alanine transaminase (ALT) and aspartate transaminase (AST), higher creatinine, lower protein and prolonged activated partial thromboplastin time (APTT) were significantly associated with prolonged fever but not platelet count or prothrombin time (PT). Saddleback fever was present in 165 (5.8%). Although DHF and SD were more likely to occur in patients in those with saddleback fever, DSS was not. Compared with prolonged fever, saddleback fever did not show many significant associations except for diarrhea, abdominal pain, clinical fluid accumulation, hematocrit and platelet change, and lower systolic blood pressure. This study demonstrates that prolonged fever may be associated with various warning signs and more severe forms of dengue (SD, DSS, DHF), while saddleback fever showed associations with DHF and SD but not DSS. The presence of prolonged or saddleback fever in dengue patients should therefore prompt

  8. Pharmacology of Ultrasonic Vocalizations in adult Rats: Significance, Call Classification and Neural Substrate.

    PubMed

    Brudzynski, Stefan M

    2015-01-01

    Pharmacological studies of emotional arousal and initiation of emotional states in rats measured by their ultrasonic vocalizations are reviewed. It is postulated that emission of vocalizations is an inseparable feature of emotional states and it evolved from mother-infant interaction. Positive emotional states are associated with emission of 50 kHz vocalizations that could be induced by rewarding situations and dopaminergic activation of the nucleus accumbens and are mediated by D1, D2, and partially D3 dopamine receptors. Three biologically significant subtypes of 50 kHz vocalizations have been identified, all expressing positive emotional states: (1) flat calls without frequency modulation that serve as contact calls during social interactions; (2) frequencymodulated calls without trills that signal rewarding and significantly motivated situation; and (3) frequency-modulated calls with trills or trills themselves that are emitted in highly emotional situations associated with intensive affective state. Negative emotional states are associated with emission of 22 kHz vocalizations that could be induced by aversive situations, muscarinic cholinergic activation of limbic areas of medial diencephalon and forebrain, and are mediated by M2 muscarinic receptors. Two biologically significant subtypes of 22 kHz vocalizations have been identified, both expressing negative emotional sates: (1) long calls that serve as alarm calls and signal external danger; and (2) short calls that express a state of discomfort without external danger. The positive and negative states with emission of vocalizations are initiated by two ascending reticular activating subsystems: the mesolimbic dopaminergic subsystem as a specific positive arousal system, and the mesolimbic cholinergic subsystem as a specific negative arousal system.

  9. Clinical Significance and Characterization of Streptococcus tigurinus Isolates in an Adult Population.

    PubMed

    Bourassa, Lori; Clarridge, J E

    2015-11-01

    Streptococcus tigurinus is a newly described member of the Streptococcus mitis group. Due to the difficulty in distinguishing viridans group streptococci (VGS) by phenotype, analysis of 16S rRNA sequences is necessary for the accurate identification of most species. Through a laboratory policy of analyzing all clinically significant isolates from the VGS group by16S rRNA gene sequencing, we identified 14 S. tigurinus isolates from 11 patients. The Vitek 2 system most commonly gave an excellent rating to an incorrect identification (e.g., Streptococcus mitis), as did matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) (e.g., Streptococcus oralis). S. tigurinus strains were recovered from numerous body sites, including the blood, peritoneal fluid, bone, synovial fluid, a perianal abscess, and an arm wound. Retrospective chart review indicated that most isolates were clinically significant, with bacteremia (n = 5), soft tissue infections (n = 3) osteomyelitis (n = 2), infected joint prosthesis (n = 2), and peritonitis (n = 2) being the most common, thus expanding the spectrum of disease associated with S. tigurinus.

  10. Significant Improvements in the Practice Patterns of Adult Related Donor Care in US Transplantation Centers.

    PubMed

    Anthias, Chloe; Shaw, Bronwen E; Kiefer, Deidre M; Liesveld, Jane L; Yared, Jean; Kamble, Rammurti T; D'Souza, Anita; Hematti, Peiman; Seftel, Matthew D; Norkin, Maxim; DeFilipp, Zachariah; Kasow, Kimberly A; Abidi, Muneer H; Savani, Bipin N; Shah, Nirali N; Anderlini, Paolo; Diaz, Miguel A; Malone, Adriana K; Halter, Joerg P; Lazarus, Hillard M; Logan, Brent R; Switzer, Galen E; Pulsipher, Michael A; Confer, Dennis L; O'Donnell, Paul V

    2016-03-01

    Recent investigations have found a higher incidence of adverse events associated with hematopoietic cell donation in related donors (RDs) who have morbidities that if present in an unrelated donor (UD) would preclude donation. In the UD setting, regulatory standards ensure independent assessment of donors, one of several crucial measures to safeguard donor health and safety. A survey conducted by the Center for International Blood and Marrow Transplant Research (CIBMTR) Donor Health and Safety Working Committee in 2007 reported a potential conflict of interest in >70% of US centers, where physicians had simultaneous responsibility for RDs and their recipients. Consequently, several international organizations have endeavored to improve practice through regulations and consensus recommendations. We hypothesized that the changes in the 2012 Foundation for the Accreditation of Cellular Therapy and the Joint Accreditation Committee-International Society for Cellular Therapy and European Society for Blood and Marrow Transplantation standards resulting from the CIBMTR study would have significantly impacted practice. Accordingly, we conducted a follow-up survey of US transplantation centers to assess practice changes since 2007, and to investigate additional areas where RD care was predicted to differ from UD care. A total of 73 centers (53%), performing 79% of RD transplantations in the United States, responded. Significant improvements were observed since the earlier survey; 62% centers now ensure separation of RD and recipient care (P < .0001). This study identifies several areas where RD management does not meet international donor care standards, however. Particular concerns include counseling and assessment of donors before HLA typing, with 61% centers first disclosing donor HLA results to an individual other than the donor, the use of unlicensed mobilization agents, and the absence of long-term donor follow-up. Recommendations for improvement are made.

  11. Significant improvements in the practice patterns of adult related donor care in US transplant centers

    PubMed Central

    MBChB, Chloe Anthias; Shaw, Bronwen E; Kiefer, Deidre M; Liesveld, Jane L; Yared, Jean; Kambl, Rammurti T; D'Souza, Anita; Hematti, Peiman; Seftel, Matthew D; Norkin, Maxim; DeFilipp, Zachariah M; Kasow, Kimberly A; Abidi, Muneer H; Savani, Bipin N; Shah, Nirali N; Anderlini, Paolo; Diaz, Miguel A; Malone, Adriana K; Halter, Joerg P; Lazarus, Hillard M; Logan, Brent R; Switzer, Galen E; Pulsipher, Michael A; Confer, Dennis L; O'Donnell, Paul V

    2016-01-01

    Recent investigations have found a higher incidence of adverse events associated with hematopoietic cell donation in related donors (RDs) who have morbidities that if present in an unrelated donor (UD) would preclude donation. In the UD setting, regulatory standards ensure independent assessment of donors, one of several crucial measures to safeguard donor health and safety. A survey conducted by the Center for International Blood and Marrow Transplant Research (CIBMTR) Donor Health and Safety Working Committee in 2007 reported a potential conflict of interest in >70% US centers, where physicians had simultaneous responsibility for RDs and their recipients. Consequently, several international organizations have endeavored to improve practice through regulations and consensus recommendations. We hypothesized that the changes in the 2012 FACT-JACIE Standards, resulting from the CIBMTR study, will have significantly impacted practice. Accordingly, a follow-up survey of US transplant centers was conducted to assess practice changes since 2007, and investigate additional areas where RD care was predicted to differ from UD care. 73 centers (53%), performing 79% of US RD transplants responded. Significant improvements were observed since the earlier survey; 62% centers now ensure separation of RD and recipient care (P<0.0001). However, this study identifies several areas where RD management does not meet international donor care standards. Particular concerns include counseling and assessment of donors before HLA typing, with 61% centers first disclosing donor HLA results to an individual other than the donor, the use of unlicensed mobilization agents, and the absence of long-term donor follow-up. Recommendations for improvement are described. PMID:26597080

  12. Adult acclimation to combined temperature and pH stressors significantly enhances reproductive outcomes compared to short-term exposures.

    PubMed

    Suckling, Coleen C; Clark, Melody S; Richard, Joelle; Morley, Simon A; Thorne, Michael A S; Harper, Elizabeth M; Peck, Lloyd S

    2015-05-01

    This study examined the effects of long-term culture under altered conditions on the Antarctic sea urchin, Sterechinus neumayeri. Sterechinus neumayeri was cultured under the combined environmental stressors of lowered pH (-0.3 and -0.5 pH units) and increased temperature (+2 °C) for 2 years. This time-scale covered two full reproductive cycles in this species and analyses included studies on both adult metabolism and larval development. Adults took at least 6-8 months to acclimate to the altered conditions, but beyond this, there was no detectable effect of temperature or pH. Animals were spawned after 6 and 17 months exposure to altered conditions, with markedly different outcomes. At 6 months, the percentage hatching and larval survival rates were greatest in the animals kept at 0 °C under current pH conditions, whilst those under lowered pH and +2 °C performed significantly less well. After 17 months, performance was not significantly different across treatments, including controls. However, under the altered conditions urchins produced larger eggs compared with control animals. These data show that under long-term culture adult S. neumayeri appear to acclimate their metabolic and reproductive physiology to the combined stressors of altered pH and increased temperature, with relatively little measureable effect. They also emphasize the importance of long-term studies in evaluating effects of altered pH, particularly in slow developing marine species with long gonad maturation times, as the effects of altered conditions cannot be accurately evaluated unless gonads have fully matured under the new conditions.

  13. Older Adults with Mild Cognitive Impairments Show Less Driving Errors after a Multiple Sessions Simulator Training Program but Do Not Exhibit Long Term Retention

    PubMed Central

    Teasdale, Normand; Simoneau, Martin; Hudon, Lisa; Germain Robitaille, Mathieu; Moszkowicz, Thierry; Laurendeau, Denis; Bherer, Louis; Duchesne, Simon; Hudon, Carol

    2016-01-01

    The driving performance of individuals with mild cognitive impairment (MCI) is suboptimal when compared to healthy older adults. It is expected that the driving will worsen with the progression of the cognitive decline and thus, whether or not these individuals should continue to drive is a matter of debate. The aim of the study was to provide support to the claim that individuals with MCI can benefit from a training program and improve their overall driving performance in a driving simulator. Fifteen older drivers with MCI participated in five training sessions in a simulator (over a 21-day period) and in a 6-month recall session. During training, they received automated auditory feedback on their performance when an error was noted about various maneuvers known to be suboptimal in MCI individuals (for instance, weaving, omitting to indicate a lane change, to verify a blind spot, or to engage in a visual search before crossing an intersection). The number of errors was compiled for eight different maneuvers for all sessions. For the initial five sessions, a gradual and significant decrease in the number of errors was observed, indicating learning and safer driving. The level of performance, however, was not maintained at the 6-month recall session. Nevertheless, the initial learning observed opens up possibilities to undertake more regular interventions to maintain driving skills and safe driving in MCI individuals. PMID:28082883

  14. Older Adults with Mild Cognitive Impairments Show Less Driving Errors after a Multiple Sessions Simulator Training Program but Do Not Exhibit Long Term Retention.

    PubMed

    Teasdale, Normand; Simoneau, Martin; Hudon, Lisa; Germain Robitaille, Mathieu; Moszkowicz, Thierry; Laurendeau, Denis; Bherer, Louis; Duchesne, Simon; Hudon, Carol

    2016-01-01

    The driving performance of individuals with mild cognitive impairment (MCI) is suboptimal when compared to healthy older adults. It is expected that the driving will worsen with the progression of the cognitive decline and thus, whether or not these individuals should continue to drive is a matter of debate. The aim of the study was to provide support to the claim that individuals with MCI can benefit from a training program and improve their overall driving performance in a driving simulator. Fifteen older drivers with MCI participated in five training sessions in a simulator (over a 21-day period) and in a 6-month recall session. During training, they received automated auditory feedback on their performance when an error was noted about various maneuvers known to be suboptimal in MCI individuals (for instance, weaving, omitting to indicate a lane change, to verify a blind spot, or to engage in a visual search before crossing an intersection). The number of errors was compiled for eight different maneuvers for all sessions. For the initial five sessions, a gradual and significant decrease in the number of errors was observed, indicating learning and safer driving. The level of performance, however, was not maintained at the 6-month recall session. Nevertheless, the initial learning observed opens up possibilities to undertake more regular interventions to maintain driving skills and safe driving in MCI individuals.

  15. Adults with dyslexia exhibit large effects of crowding, increased dependence on cues, and detrimental effects of distractors in visual search tasks.

    PubMed

    Moores, Elisabeth; Cassim, Rizan; Talcott, Joel B

    2011-12-01

    Difficulties in visual attention are increasingly being linked to dyslexia. To date, the majority of studies have inferred functionality of attention from response times to stimuli presented for an indefinite duration. However, in paradigms that use reaction times to investigate the ability to orient attention, a delayed reaction time could also indicate difficulties in signal enhancement or noise exclusion once oriented. Thus, in order to investigate attention modulation and visual crowding effects in dyslexia, this study measured stimulus discrimination accuracy to rapidly presented displays. Adults with dyslexia (AwD) and controls discriminated the orientation of a target in an array of different numbers of - and differently spaced - vertically orientated distractors. Results showed that AwD: were disproportionately impacted by (i) close spacing and (ii) increased numbers of stimuli, (iii) did use pre-cues to modulate attention, but (iv) used cues less successfully to counter effects of increasing numbers of distractors. A greater dependence on pre-cues, larger effects of crowding and the impact of increased numbers of distractors all correlated significantly with measures of literacy. These findings extend previous studies of visual crowding of letters in dyslexia to non-complex stimuli. Overall, AwD do not use cues less, but they do use cues less successfully. We conclude that visual attention is an important factor to consider in the aetiology of dyslexia. The results challenge existing theoretical accounts of visual attention deficits, which alone are unable to comprehensively explain the pattern of findings demonstrated here.

  16. Methylphenidate significantly improves driving performance of adults with attention-deficit hyperactivity disorder: a randomized crossover trial.

    PubMed

    Verster, Joris C; Bekker, Evelijne M; de Roos, Marlise; Minova, Anita; Eijken, Erik J E; Kooij, J J Sandra; Buitelaar, Jan K; Kenemans, J Leon; Verbaten, Marinus N; Olivier, Berend; Volkerts, Edmund R

    2008-05-01

    Although patients with attention-deficit hyperactivity disorder (ADHD) have reported improved driving performance on methylphenidate, limited evidence exists to support an effect of treatment on driving performance and some regions prohibit driving on methylphenidate. A randomized, crossover trial examining the effects of methylphenidate versus placebo on highway driving in 18 adults with ADHD was carried out. After three days of no treatment, patients received either their usual methylphenidate dose (mean: 14.7 mg; range: 10-30 mg) or placebo and then the opposite treatment after a six to seven days washout period. Patients performed a 100 km driving test during normal traffic, 1.5 h after treatment administration. Standard deviation of lateral position (SDLP), the weaving of the car, was the primary outcome measure. Secondary outcome measurements included the standard deviation of speed and patient reports of driving performance. Driving performance was significantly better in the methylphenidate than in the placebo condition, as reflected by the SDLP difference (2.3 cm, 95% CI = 0.8-3.8, P = 0.004). Variation in speed was similar on treatment and on placebo (-0.05 km/h, 95% CI = -0.4 to 0.2, P = 0.70). Among adults with ADHD, with a history of a positive clinical response to methylphenidate, methylphenidate significantly improves driving performance.

  17. Ferrous Sulfate Supplementation Causes Significant Gastrointestinal Side-Effects in Adults: A Systematic Review and Meta-Analysis

    PubMed Central

    Tolkien, Zoe; Stecher, Lynne; Mander, Adrian P.; Pereira, Dora I. A.; Powell, Jonathan J.

    2015-01-01

    Background The tolerability of oral iron supplementation for the treatment of iron deficiency anemia is disputed. Objective Our aim was to quantify the odds of GI side-effects in adults related to current gold standard oral iron therapy, namely ferrous sulfate. Methods Systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating GI side-effects that included ferrous sulfate and a comparator that was either placebo or intravenous (IV) iron. Random effects meta-analysis modelling was undertaken and study heterogeneity was summarised using I2 statistics. Results Forty three trials comprising 6831 adult participants were included. Twenty trials (n = 3168) had a placebo arm and twenty three trials (n = 3663) had an active comparator arm of IV iron. Ferrous sulfate supplementation significantly increased risk of GI side-effects versus placebo with an odds ratio (OR) of 2.32 [95% CI 1.74–3.08, p<0.0001, I2 = 53.6%] and versus IV iron with an OR of 3.05 [95% CI 2.07-4.48, p<0.0001, I2 = 41.6%]. Subgroup analysis in IBD patients showed a similar effect versus IV iron (OR = 3.14, 95% CI 1.34-7.36, p = 0.008, I2 = 0%). Likewise, subgroup analysis of pooled data from 7 RCTs in pregnant women (n = 1028) showed a statistically significant increased risk of GI side-effects for ferrous sulfate although there was marked heterogeneity in the data (OR = 3.33, 95% CI 1.19-9.28, p = 0.02, I2 = 66.1%). Meta-regression did not provide significant evidence of an association between the study OR and the iron dose. Conclusions Our meta-analysis confirms that ferrous sulfate is associated with a significant increase in gastrointestinal-specific side-effects but does not find a relationship with dose. PMID:25700159

  18. Serum Vitamin D Is Significantly Inversely Associated with Disease Severity in Caucasian Adults with Obstructive Sleep Apnea Syndrome

    PubMed Central

    Kerley, Conor P.; Hutchinson, Katrina; Bolger, Kenneth; McGowan, Aisling; Faul, John; Cormican, Liam

    2016-01-01

    Study Objectives: To evaluate vitamin D (25(OH)D) levels in obstructive sleep apnea syndrome (OSAS) and possible relationships to OSAS severity, sleepiness, lung function, nocturnal heart rate (HR), and body composition. We also aimed to compare the 25(OH)D status of a subset of OSAS patients compared to controls matched for important determinants of both OSAS and vitamin D deficiency (VDD). Methods: This was a cross-sectional study conducted at an urban, clinical sleep medicine outpatient center. We recruited newly diagnosed, Caucasian adults who had recently undergone nocturnal polysomnography. We compared body mass index (BMI), body composition (bioelectrical impedance analysis), neck circumference, sleepiness (Epworth Sleepiness Scale), lung function, and vitamin D status (serum 25-hydrpoxyvitamin D (25(OH)D) across OSAS severity categories and non-OSAS subjects. Next, using a case-control design, we compared measures of serum 25(OH)D from OSAS cases to non-OSAS controls who were matched for age, gender, skin pigmentation, sleepiness, season, and BMI. Results: 106 adults (77 male; median age = 54.5; median BMI = 34.3 kg/m2) resident in Dublin, Ireland (latitude 53°N) were recruited and categorized as non-OSAS or mild/moderate/severe OSAS. 98% of OSAS cases had insufficient 25(OH)D (< 75 nmol/L), including 72% with VDD (< 50 nmol/L). 25(OH)D levels decreased with OSAS severity (P = 0.003). 25(OH)D was inversely correlated with BMI, percent body fat, AHI, and nocturnal HR. Subsequent multivariate regression analysis revealed that 25(OH)D was independently associated with both AHI (P = 0.016) and nocturnal HR (P = 0.0419). Our separate case-control study revealed that 25(OH)D was significantly lower in OSAS cases than matched, non-OSAS subjects (P = 0.001). Conclusions: We observed widespread vitamin D deficiency and insufficiency in a Caucasian, OSAS population. There were significant, independent, inverse relationships between 25(OH)D and AHI as well as

  19. Face-to-Face Sharing with Strangers and Altruistic Punishment of Acquaintances for Strangers: Young Adolescents Exhibit Greater Altruism than Adults

    PubMed Central

    Hao, Jian; Yang, Yue; Wang, Zhiwen

    2016-01-01

    Young adolescents are generally considered to be self-absorbed. Studies indicate that they lack relevant general cognitive abilities, such as impulse control, that mature in early adulthood. However, their idealism may cause them to be more intolerant of unfair treatment to others and thus result in their engaging in more altruistic behavior. The present study aimed to clarify whether young adolescents are more altruistic than adults and thus indicate whether altruistic competence is domain-specific. One hundred 22 young adolescents and adults participated in a face-to-face, two-round, third-party punishment experiment. In each interaction group, a participant served as an allocator who could share money units with a stranger; another participant who knew the allocator could punish the acquaintance for the stranger. Participants reported their emotions after the first round, and at the end of the experiment, the participants justified their behavior in each round. The results indicated that the young adolescents both shared more and punished more than did the adults. Sharing was associated with a reference to fairness in the justifications, but altruistic punishment was associated with subsequent positive emotion. In sum, greater altruism in young adolescents compared to adults with mature cognitive abilities provides evidence of domain-specificity of altruistic competence. Moreover, sharing and altruistic punishment are related to specific cognitive and emotional mechanisms, respectively. PMID:27752246

  20. Face-to-Face Sharing with Strangers and Altruistic Punishment of Acquaintances for Strangers: Young Adolescents Exhibit Greater Altruism than Adults.

    PubMed

    Hao, Jian; Yang, Yue; Wang, Zhiwen

    2016-01-01

    Young adolescents are generally considered to be self-absorbed. Studies indicate that they lack relevant general cognitive abilities, such as impulse control, that mature in early adulthood. However, their idealism may cause them to be more intolerant of unfair treatment to others and thus result in their engaging in more altruistic behavior. The present study aimed to clarify whether young adolescents are more altruistic than adults and thus indicate whether altruistic competence is domain-specific. One hundred 22 young adolescents and adults participated in a face-to-face, two-round, third-party punishment experiment. In each interaction group, a participant served as an allocator who could share money units with a stranger; another participant who knew the allocator could punish the acquaintance for the stranger. Participants reported their emotions after the first round, and at the end of the experiment, the participants justified their behavior in each round. The results indicated that the young adolescents both shared more and punished more than did the adults. Sharing was associated with a reference to fairness in the justifications, but altruistic punishment was associated with subsequent positive emotion. In sum, greater altruism in young adolescents compared to adults with mature cognitive abilities provides evidence of domain-specificity of altruistic competence. Moreover, sharing and altruistic punishment are related to specific cognitive and emotional mechanisms, respectively.

  1. Associations between hurtful weight-related comments by family and significant other and the development of disordered eating behaviors in young adults.

    PubMed

    Eisenberg, Marla E; Berge, Jerica M; Fulkerson, Jayne A; Neumark-Sztainer, Dianne

    2012-10-01

    Research has found that weight-teasing is associated with disordered eating in adolescents. This study expands on the existing research by examining associations between hurtful weight comments by family and a significant other and disordered eating in young adults. Data come from 1,902 young adults (mean age 25) who completed surveys in 1998, 2003 and 2009. Correlations were examined between receiving hurtful comments from family and significant others, and four disordered eating behaviors in young adulthood, adjusting for prior disordered eating and prior teasing. Disordered eating behaviors were common in young adulthood, and were associated with hearing hurtful weight-related comments from family members and a significant other, for both females and males. Disordered eating prevention activities, which include messages about the potential harm associated with hurtful weight-related comments, should be expanded to address young adults, and programs may want to target relationship partners.

  2. Maurice Gee's Brilliant Borrowings of Maurice Gee and Significant Others: Realism and Postmodernism in Gee's Books for Children and Adults

    ERIC Educational Resources Information Center

    van Rij, Vivien

    2013-01-01

    This paper examines the work of one of New Zealand's most acclaimed writers, Maurice Gee, and the use of his children's fiction as an experimental ground for postmodernist techniques further developed in his writing for adults. In particular, it considers Gee's borrowings of his own and others' non-fictional and fictional material, to produce…

  3. Adult Trade Apprentices: Exploring the Significance of Recognition of Prior Learning and Skill Sets for Earlier Completion. Research Report

    ERIC Educational Resources Information Center

    Hargreaves, Jo; Blomberg, Davinia

    2015-01-01

    The nature of apprenticeships is changing. Increasing proportions of adult apprentices are prompting demand for various alternative pathways to completion. One option for an alternative pathway to accelerate completion is the use of recognition of prior learning (RPL) to identify existing skills and knowledge in combination with gap training. This…

  4. Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Anti-Tumor Activity in Cancer Cells that Display Resistance to Proapoptotic Stimuli: an Investigation of Structure-Activity Relationship and Mechanistic Insight

    PubMed Central

    Lamoral-Theys, Delphine; Andolfi, Anna; Van Goietsenoven, Gwendoline; Cimmino, Alessio; Le Calvé, Benjamin; Wauthoz, Nathalie; Mégalizzi, Véronique; Gras, Thierry; Bruyère, Céline; Dubois, Jacques; Mathieu, Véronique; Kornienko, Alexander; Kiss, Robert; Evidente, Antonio

    2011-01-01

    Twenty-two lycorine-related compounds were investigated for in vitro anti-tumor activity using four cancer cell lines displaying different levels of resistance to pro-apoptotic stimuli and two cancer cell lines sensitive to pro-apoptotic stimuli. Lycorine and six of its congeners exhibited potency in the single-digit micromolar range, while no compound appeared more active than lycorine. Lycorine also displayed the highest potential (in vitro) therapeutic ratio, being at least 15 times more active against cancer than normal cells. Our studies also showed that lycorine exerts its in vitro anti-tumor activity through cytostatic rather than cytotoxic effects. Furthermore, lycorine provided significant therapeutic benefit in mice bearing brain grafts of the B16F10 melanoma model at non-toxic doses. Thus, the results of the current study make lycorine an excellent lead for the generation of compounds able to combat cancers, which are naturally resistant to pro-apoptotic stimuli, such as glioblastoma, melanoma, non-small-cell-lung cancers, metastatic cancers, among others. PMID:19788245

  5. Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.

    PubMed

    Lamoral-Theys, Delphine; Andolfi, Anna; Van Goietsenoven, Gwendoline; Cimmino, Alessio; Le Calvé, Benjamin; Wauthoz, Nathalie; Mégalizzi, Véronique; Gras, Thierry; Bruyère, Céline; Dubois, Jacques; Mathieu, Véronique; Kornienko, Alexander; Kiss, Robert; Evidente, Antonio

    2009-10-22

    Twenty-two lycorine-related compounds were investigated for in vitro antitumor activity using four cancer cell lines displaying different levels of resistance to proapoptotic stimuli and two cancer cell lines sensitive to proapoptotic stimuli. Lycorine and six of its congeners exhibited potency in the single-digit micromolar range, while no compound appeared more active than lycorine. Lycorine also displayed the highest potential (in vitro) therapeutic ratio, being at least 15 times more active against cancer than normal cells. Our studies also showed that lycorine exerts its in vitro antitumor activity through cytostatic rather than cytotoxic effects. Furthermore, lycorine provided significant therapeutic benefit in mice bearing brain grafts of the B16F10 melanoma model at nontoxic doses. Thus, the results of the current study make lycorine an excellent lead for the generation of compounds able to combat cancers, which are naturally resistant to proapoptotic stimuli, such as glioblastoma, melanoma, non-small-cell-lung cancers, and metastatic cancers, among others.

  6. Cognitive behavior therapy-based psychoeducational groups for adults with ADHD and their significant others (PEGASUS): an open clinical feasibility trial.

    PubMed

    Hirvikoski, T; Waaler, E; Lindström, T; Bölte, S; Jokinen, J

    2015-03-01

    The aim of this pilot study was to investigate the feasibility and effectiveness of a new psychoeducative intervention program (PEGASUS) for adults with ADHD and their significant others in a psychiatric outpatient context. At three outpatient psychiatric clinics, adults with ADHD and their significant others took part in PEGASUS, a psychoeducational program based on theories from cognitive behavioral therapy, neuropsychology, and cross-disciplinary evidence regarding ADHD. In total, 108 adults were allocated to treatment (51 with ADHD and their 57 significant others). Feasibility was evaluated regarding suitability of the intervention at a psychiatric outpatient clinic and treatment completion. Preliminary efficacy was evaluated per protocol from baseline to post-intervention (n = 41 adults with ADHD and 40 significant others). In a feasibility analysis, the intervention was judged to be a suitable treatment option for 94.5 % of all individuals with a primary diagnosis of ADHD at an outpatient psychiatric clinic. In total, 43 out of 51 allocated individuals with ADHD (84.3 %) completed the intervention. The corresponding figures for their significant others were 42 out of 57 (73.7 %). Knowledge about ADHD increased, and both the quality of relationships and psychological well-being improved from baseline to post-intervention in all participants. The significant others reported a reduction in the subjective burden of care, such as worry and guilt. The objective burden of care (such as financial problems) did not change. The findings support the potential value of psychoeducation for adults with ADHD and their significant others. An ongoing randomized controlled trial will generate further evidence concerning the PEGASUS program.

  7. Crossing the Finish Line: Helping Adults with Significant College Credit Get Back on Track to a College Degree. Complete to Compete Briefing Paper

    ERIC Educational Resources Information Center

    Michelau, Demaree K.

    2011-01-01

    Nearly all states are grappling with the question of how to boost college attainment to meet workforce needs with the resources available. For many states, that task is complicated by the fact that the young adult population is projected neither to grow nor decline over the next several years. There is a significant opportunity, however, for…

  8. Varying protein source and quantity does not significantly improve weight loss, fat loss, or satiety in reduced energy diets among midlife adults

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This pilot study tested whether varying protein source and quantity in a reduced energy diet would result in significant differences in weight, body composition, and renin angiotensin aldosterone system activity in midlife adults. Eighteen subjects enrolled in a 5 month weight reduction study, invol...

  9. GC-MS metabolomic analysis reveals significant alterations in cerebellar metabolic physiology in a mouse model of adult onset hypothyroidism.

    PubMed

    Constantinou, Caterina; Chrysanthopoulos, Panagiotis K; Margarity, Marigoula; Klapa, Maria I

    2011-02-04

    Although adult-onset hypothyroidism (AOH) has been connected to neural activity alterations, including movement, behavioral, and mental dysfunctions, the underlying changes in brain metabolic physiology have not been investigated in a systemic and systematic way. The current knowledge remains fragmented, referring to different experimental setups and recovered from various brain regions. In this study, we developed and applied a gas chromatography-mass spectrometry (GC-MS) metabolomics protocol to obtain a holistic view of the cerebellar metabolic physiology in a Balb/cJ mouse model of prolonged adult-onset hypothyroidism induced by a 64-day treatment with 1% potassium perchlorate in the drinking water of the animals. The high-throughput analysis enabled the correlation between multiple parallel-occurring metabolic phenomena; some have been previously related to AOH, while others implicated new pathways, designating new directions for further research. Specifically, an overall decline in the metabolic activity of the hypothyroid compared to the euthyroid cerebellum was observed, characteristically manifested in energy metabolism, glutamate/glutamine metabolism, osmolytic/antioxidant capacity, and protein/lipid synthesis. These alterations provide strong evidence that the mammalian cerebellum is metabolically responsive to AOH. In light of the cerebellum core functions and its increasingly recognized role in neurocognition, these findings further support the known phenotypic manifestations of AOH into movement and cognitive dysfunctions.

  10. Reference values of total serum IgE and their significance in the diagnosis of allergy in young European adults.

    PubMed

    Carosso, Aurelia; Bugiani, Massimiliano; Migliore, Enrica; Antò, Josep Maria; DeMarco, Roberto

    2007-01-01

    Allergic sensitization mediated by immunoglobulin E (IgE) is the basis of allergic diseases, and elevated total IgE, in spite of some well-known limitations, is frequently included as a diagnostic criterion for allergic diseases. The reference value of total IgE (IgE-t) in the literature (1.5-144 kU/l) was established almost 2 decades ago. The aim of this study was to establish IgE-t reference values, establishing an updated cutoff value able to identify atopic subjects, defined as a positive CAP-radioallergosorbent test to at least one of a panel of common allergens, among young European adults. The study included 6,670 subjects from 10 Western European countries within the framework of the European Community Respiratory Health Survey II. IgE-t and specific IgE (IgE-s) were measured for the main inhalant allergens; IgE-s in class 0 for all allergens (66.2%) characterized non-atopy. The reference values were estimated by means of linear regression using a 50% random subsample of non-atopic subjects. Two non-atopic subsamples were examined so that one subsample could be used to establish reference IgE-t values, and these values were compared to those in the second non-atopic subsample to validate the findings. Sensitivity and specificity for atopy were assessed on the other 50% of non-atopic and on all atopic subjects. The 95th percentile of IgE-t reference values in non-smokers was 148 kU/l in women and 169 kU/l in men, while it was 194 and 220 kU/l in female and male smokers, respectively: serum IgE-t above the 95th percentile identifies <32% and above the 99th percentile <20% of atopic adults (low sensitivity), but a serum IgE-t below the 95th percentile identifies >90% and below the 99th percentile identifies >95% of non-atopic adults (good specificity). Due to the adequate specificity, IgE-t values exceeding the normal limits confirm a suspected atopic status; however, because of the low sensitivity, values below the cutoff seem not to exclude an atopic status

  11. The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.

    PubMed

    Kerr, Niall C H; Gao, Zhan; Holmes, Fiona E; Hobson, Sally-Ann; Hancox, Jules C; Wynick, David; James, Andrew F

    2007-06-01

    Nav1.5 is the principal voltage-gated sodium channel expressed in heart, and is also expressed at lower abundance in embryonic dorsal root ganglia (DRG) with little or no expression reported postnatally. We report here the expression of Nav1.5 mRNA isoforms in adult mouse and rat DRG. The major isoform of mouse DRG is Nav1.5a, which encodes a protein with an IDII/III cytoplasmic loop reduced by 53 amino acids. Western blot analysis of adult mouse DRG membrane proteins confirmed the expression of Nav1.5 protein. The Na+ current produced by the Nav1.5a isoform has a voltage-dependent inactivation significantly shifted to more negative potentials (by approximately 5 mV) compared to the full-length Nav1.5 when expressed in the DRG neuroblastoma cell line ND7/23. These results imply that the alternatively spliced exon 18 of Nav1.5 plays a role in channel inactivation and that Nav1.5a is likely to make a significant contribution to adult DRG neuronal function.

  12. Electrogastrography in Adults and Children: The Strength, Pitfalls, and Clinical Significance of the Cutaneous Recording of the Gastric Electrical Activity

    PubMed Central

    Indrio, Flavia

    2013-01-01

    Cutaneous electrogastrography (EGG) is a non-invasive technique to record gastric myoelectrical activity from the abdominal surface. Although the recent rapid increase in the development of electrocardiography, EGG still suffers from several limitations. Currently, computer analysis of EGG provides few reliable parameters, such as frequency and the percentage of normal and altered slow wave activity (bradygastria and tachygastria). New EGG hardware and software, along with an appropriate arrangement of abdominal electrodes, could detect the coupling of the gastric slow wave from the EGG. At present, EGG does not diagnose a specific disease, but it puts in evidence stomach motor dysfunctions in different pathological conditions as gastroparesis and functional dyspepsia. Despite the current pitfalls of EGG, a multitasking diagnostic protocol could involve the EGG and the 13C-breath testing for the evaluation of the gastric emptying time—along with validated gastrointestinal questionnaires and biochemical evaluations of the main gastrointestinal peptides—to identify dyspeptic subgroups. The present review tries to report the state of the art about the pathophysiological background of the gastric electrical activity, the recording and processing methodology of the EGG with particular attention to multichannel recording, and the possible clinical application of the EGG in adult and children. PMID:23762836

  13. Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia.

    PubMed

    Ge, Zheng; Guo, Xing; Li, Jianyong; Hartman, Melanie; Kawasawa, Yuka Imamura; Dovat, Sinisa; Song, Chunhua

    2015-12-08

    Increased expression of c-MYC is observed in both Acute Myeloid Leukemia (AML) and T-cell Acute Lymphoblastic Leukemia (T-ALL). MYC binding protein 2 (MYCBP2) is a probable E3 ubiquitin ligase and its function in leukemia is unknown. IKZF1 deletion is associated with the development and poor outcome of ALL. Here, we observed significant high c-MYC expression and low MYCBP2 expression in adult ALL patients. Patients with high c-MYC expression and/or low MYCBP2 expression had higher WBC counts and a higher percentage of CD34+ or CD33+ cells, as well as splenomegaly, liver infiltration, higher BM blasts, and lower CR rate. Ikaros bound to the regulatory regions of c-MYC and MYCBP2, suppressed c-MYC and increased MYCBP2 expression in ALL cells. Expression of c-MYC mRNA was significantly higher in patients with IKZF1 deletion; conversely MYCBP2 mRNA expression was significantly lower in those patients. A CK2 inhibitor, which acts as an Ikaros activator, also suppressed c-MYC and increased MYCBP2 expression in an Ikaros (IKZF1) dependent manner in the ALL cells. In summary, our data indicated the correlation of high c-MYC expression, low MYCBP2 expression and high c-MYC plus low MYCBP2 expression with high-risk factors and proliferation markers in adult ALL patients. Our data also revealed an oncogenic role for an Ikaros/MYCBP2/c-MYC axis in adult ALL, providing a mechanism of target therapies that activate Ikaros in adult ALL.

  14. An association, in adult Japanese, between the occurrence of rogue cells among cultured lymphocytes (JC virus activity) and the frequency of "simple" chromosomal damage among the lymphocytes of persons exhibiting these rogue cells.

    PubMed Central

    Neel, J V

    1998-01-01

    Data from a previous study of the cytogenetic effects, in cultured lymphocytes, of exposure to the atomic bomb in Hiroshima have been reanalyzed to determine the relationship between the occurrence of "rogue" cells in an individual and the frequency of "simple" chromosomal damage in the nonrogue cells of the same individual. Rogue cells are cells with complex chromosomal damage, currently believed to be a manifestation of the activity of a human polyoma virus termed "JC." Among a total of 1,835 persons examined, there were 45 exhibiting rogue cells. A total of 179,599 cells were scored for simple chromosomal damage. In both the exposed and the control populations, there was an absolute increase of approximately 1.5% in the frequency of simple chromosomal damage in the nonrogue cells of those exhibiting rogue cells, when compared with the frequencies observed in those not exhibiting rogue cells, which is a statistically significant difference. It is argued that this phenomenon, occurring not only in lymphocytes but possibly also in other cells/tissues, may play a contributory role in the origin of malignancies characterized by clonal chromosome abnormalities. Unexpectedly, among those exhibiting rogue cells, there was a disproportionately greater representation of persons who had received relatively high radiation exposures from the bomb. The reason for this is unclear, but it is tempting to relate the finding to some lingering effect of the exposure (or the circumstances surrounding the exposure) on immunocompetence. PMID:9683586

  15. Small non-polar complexes exhibiting significant piezoelectric properties: Solvothermal synthesis and crystal structures of MO5V(tren)·H2O (M=Mo and W; tren=tris(2-aminoethyl)amine)

    NASA Astrophysics Data System (ADS)

    Rasmussen, M.; Näther, C.; Bismayer, U.; Bensch, W.

    2012-11-01

    The two isostructural complexes MO5V(tren)·H2O (M=Mo (1) and W (2)) were synthesized under solvothermal conditions at pH≈12 crystallizing in the non-centrosymmetric space group P212121. The structures are constructed by a distorted tetrahedral [MO4]2- anion bound via one shared oxygen atom to a severely distorted [VIVN4O]2+ complex completing the octahedral coordination around the V centre. The two O atoms in the VN4O2 octahedron are in cis position. The two compounds represent rare examples where the [MO4]2- anion is acting as a ligand. Both compounds exhibit a piezoelectric effect which is more pronounced for M=Mo. The samples are further characterized with IR and UV/Vis spectroscopy and thermal analysis.

  16. Ethics on Exhibit

    ERIC Educational Resources Information Center

    Vick, Randy M.

    2011-01-01

    This article discusses ethical questions raised by an exhibition of work by an artist with a history of mental illness and the exhibition's relevance to art therapy and “outsider art” discourse on the subject. Considerations for how such an exhibit could be handled had the circumstances included an art therapist and art therapy client are…

  17. Community perceptions on the significant extension of life: an exploratory study among urban adults in Brisbane, Australia.

    PubMed

    Underwood, Mair; Bartlett, Helen P; Partridge, Brad; Lucke, Jayne; Hall, Wayne D

    2009-02-01

    Some researchers in the field of ageing claim that significant extension of the human lifespan will be possible in the near future. While many of these researchers have assumed that the community will welcome this technology, there has been very little research on community attitudes to life extension. This paper presents the results of an in-depth qualitative study of community attitudes to life extension across age groups and religious boundaries. There were 57 individual interviews, and 8 focus groups (totalling 72 focus group participants) conducted with community members in Brisbane, Australia. Community attitudes to life extension were more varied and complex than have been assumed by some biogerontologists and bioethicists. While some participants would welcome the opportunity to extend their lives others would not even entertain the possibility. This paper details these differences of opinion and reveals contrasting positions that reflect individualism or social concern among community members. The findings also highlight the relationship between Christianity, in particular belief in an afterlife, and attitudes to life extension technology. Overall, the study raises questions about the relationship between interest in life extension, the medicalisation of ageing and the increasing acceptability of enhancement technologies that need to be addressed in more representative samples of the community.

  18. The significance of the host inflammatory response on the therapeutic efficacy of cell therapies utilising human adult stem cells

    SciTech Connect

    Navarro, Melba; Pu, Fanrong; Hunt, John A.

    2012-02-15

    Controlling the fate of implanted hMSCs is one of the major drawbacks to be overcome to realize tissue engineering strategies. In particular, the effect of the inflammatory environment on hMSCs behaviour is poorly understood. Studying and mimicking the inflammatory process in vitro is a very complex and challenging task that involves multiple variables. This research addressed the questions using in vitro co-cultures of primary derived hMSCs together with human peripheral blood mononucleated cells (PBMCs); the latter are key agents in the inflammatory process. This work explored the in vitro phenotypic changes of hMSCs in co-culture direct contact with monocytes and lymphocytes isolated from blood using both basal and osteogenic medium. Our findings indicated that hMSCs maintained their undifferentiated phenotype and pluripotency despite the contact with PBMCs. Moreover, hMSCs demonstrated increased proliferation and were able to differentiate specifically down the osteogenic lineage pathway. Providing significant crucial evidence to support the hypothesis that inflammation and host defence mechanisms could be utilised rather than avoided and combated to provide for the successful therapeutic application of stem cell therapies.

  19. An Exhibit for Touching.

    ERIC Educational Resources Information Center

    Hunt, Susan

    1979-01-01

    An exhibit designed for visually handicapped persons presented by the Kalamazoo (Michigan) Institute of Art included bronze sculptures and oil paintings from the institute's permanent collection. (CL)

  20. A Teaching Aids Exhibition.

    ERIC Educational Resources Information Center

    Mahanja, Salah

    1985-01-01

    Describes an exhibition for the benefit of teachers of English in Arab Primary Schools, which was prepared by third-year students at the Teachers College for Arab Teachers. The exhibition included games, songs, audiovisual aids, crossword puzzles, vocabulary, spelling booklets, preposition aids, and worksheet and lesson planning aids. (SED)

  1. Communicating Science through Exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, P.; Harold, J.; Morrow, C.

    It is critically important for the public to better understand the scientific process. Museum exhibitions are an important part of informal science education that can effectively reach public audiences as well as school groups. They provide an important gateway for the public to learn about compelling scientific endeavors. There are many ways for scientists to help develop science exhibitions. The Space Science Institute (SSI) is a national leader in producing traveling science exhibitions and their associated educational programming (i.e. interactive websites, educator workshops, public talks, instructional materials). Two of its exhibitions, Space Weather Center and MarsQuest, are currently on tour. Another exhibition, Alien Earths, is in development. The Space Weather Center was developed in partnership with various research missions at NASA's Goddard Space Flight Center. MarsQuest is a 5000 square-foot traveling exhibition. The exhibit's second 3-year tour began this January at the Detroit Science Center. It is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and to learn more about their own planet in the process. The 3,000 square-foot traveling exhibition, called Alien Earths, will bring origins-related research and discoveries to students and the American public. Alien Earths has four interrelated exhibit areas: Our Place in Space, Star Birth, PlanetQuest, and Search for Life. Exhibit visitors will explore the awesome events surrounding the birth of stars and planets; they will join scientists in the hunt for planets outside our solar system including those that may be in ``habitable zones'' around other stars; and finally they will be able to learn about how scientists are looking for signs of life beyond Earth. Besides the exhibits, SSI is also developing interactive web sites based on exhibit themes. New technologies are transforming the Web from a static medium to an interactive environment with tremendous

  2. Healthy sheep that differ in scrapie associated PRNP genotypes exhibit significant differences of expression pattern associated with immune response and cell-to-cell signalling in retropharyngeal lymph nodes.

    PubMed

    Komolka, Katrin; Ponsuksili, Siriluck; Schwerin, Manfred

    2013-04-15

    The present study was conducted to test the hypothesis whether prion protein gene (PRNP) associated scrapie susceptibility is connected with physiological changes in tissue involved in pathogen uptake, migration and propagation. Jejunum, ileal Peyer's patches, retropharyngeal lymph nodes, brain stem and liver of healthy and non scrapie-infected sheep with PRNP genotypes representing the scrapie risk class R1 (scrapie-resistant) and R5 (scrapie-susceptible), respectively, were comparatively analysed by microarray technology and quantitative reverse transcriptase polymerase chain reaction (RT qPCR). Significantly higher expression levels of genes involved in immune response and cell communication pathways in retropharyngeal lymph nodes of R1 sheep in comparison with R5 animals strongly suggest PRNP associated physiological processes with impact as an early barrier in pathogen defence. Equal expression patterns in brain stem suggest no physiological differences in brain of healthy R1 and R5 animals. In addition, similar expression pattern in liver indicates that there are no transcriptional differences in genes of the hepatic energy metabolism between animals of scrapie classes R1 and R5.

  3. New Hurricane Exhibit

    NASA Technical Reports Server (NTRS)

    2007-01-01

    A new exhibit in StenniSphere depicting NASA's role in hurricane prediction and research and SSC's role in helping the region recover from Hurricane Katrina. The cyclone-shaped exhibit focuses on the effects of the Aug. 29, 2005 storm and outlines how NASA is working to improve weather forecasting. Through photos, 3-D models and digital animations, the exhibit tells the story of what happened inside the storm and how NASA's scientific research can increase the accuracy of hurricane tracking and modeling.

  4. Test Control Center exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.

  5. Communicating Science through Exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, Paul

    2005-04-01

    It is critically important for the public to better understand the scientific process. Museum exhibitions are an important part of informal science education that can effectively reach public audiences as well as school groups. They provide an important gateway for the public to learn about compelling scientific endeavors. Science exhibitions also provide a marvelous opportunity for scientists to become engaged in the exhibit development process. The Space Science Institute (SSI) is a national leader in producing traveling science exhibitions and their associated educational programming (i.e. interactive websites, educator workshops, public talks, instructional materials). The focus of this presentation will be on two of its exhibit projects: MarsQuest (on tour for four years) and Alien Earths (its tour began early in 2005). MarsQuest is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and to learn more about their own planet in the process. Alien Earths will bring origins-related research and discoveries to students and the American public. It has four interrelated exhibit areas: Our Place in Space, Star Birth, Planet Quest, and Search for Life. Exhibit visitors will explore the awesome events surrounding the birth of stars and planets; they will join scientists in the hunt for planets outside our solar system including those that may be in ``habitable zones'' around other stars; and finally they will be able to learn about how scientists are looking for signs of life beyond Earth. SSI is also developing interactive web sites based on exhibit themes. New technologies are transforming the Web from a static medium to an interactive environment with tremendous potential for informal education and inquiry-based investigations. This talk will focus on the role informal science projects play in effectively communicating science to a broad, public audience.

  6. The International Classification of Functioning, Disability and Health as a Framework for Providing Patient- and Family-Centered Audiological Care for Older Adults and Their Significant Others.

    PubMed

    Grenness, Caitlin; Meyer, Carly; Scarinci, Nerina; Ekberg, Katie; Hickson, Louise

    2016-08-01

    Hearing impairment is highly prevalent in the older population, and it impacts communication and quality of life for both the people with the hearing difficulties and their significant others. In this article, typical audiological assessment and management of an older adult is contrasted with a best practice approach wherein the World Health Organization's International Classification of Functioning, Disability and Health (ICF) framework is applied. The aim of the comparison is to demonstrate how the ICF expands our focus: rather than merely focusing on impairment, we also consider the activities, participation, and contextual factors for both the person with the hearing impairment and his or her family. A case example of an older patient and her spouse is provided, and their shared experience of the patient's hearing impairment is mapped onto the ICF framework. Family-centered hearing care is recommended for individualizing care and improving outcomes for older patients and their families.

  7. The dimensions and role of commensality: A theoretical model drawn from the significance of communal eating among adults in Santiago, Chile.

    PubMed

    Giacoman, Claudia

    2016-12-01

    This article examines the significance of communal eating among adults from Santiago, Chile, by elaborating on a theoretical model for commensality that is based on empirical material. Based on this objective, 24 group interviews were conducted in Santiago with family members, coworkers, and friends who shared meals with one another. The results showed that the practice of commensality strengthens the cohesion among the members of a group, providing an interactive space in which communal belonging is symbolized and shared norms are respected. However, eating together also is assigned an ambiguous value: On the one hand, commensality is viewed as positive in enabling connections with others. On the other hand, participating in commensality can be viewed as negative, causing tensions depending on the characteristics of the commensal group and the context.

  8. An Evidence-Based Education Program for Adults about Child Sexual Abuse (“Prevent It!”) That Significantly Improves Attitudes, Knowledge, and Behavior

    PubMed Central

    Martin, Erin K.; Silverstone, Peter H.

    2016-01-01

    Here we describe the development of an evidence-based education program for adults about childhood sexual abuse (CSA), called Prevent It! Uniquely, the primary goal of this program was to change the behavior of participants, as well as to increase knowledge about CSA and positive attitudes toward it. A comprehensive review shows no previous similar approach. The program includes a detailed manual to allow standardized administration by trained facilitators, as well as multiple video segments from CSA survivors and professionals. A total of 23 program workshops were run, with 366 adults participating. Of these, 312 (85%) agreed to take part in the study. All completed baseline ratings prior to the program and 195 (63% of study sample) completed follow-up assessments at 3-months. There were no significant differences between the demographic make-up of the baseline group and the follow-up group. Assessments included demographic data, knowledge, attitudes, and several measures of behavior (our primary outcome variable). Behavioral questions asked individuals to select behaviors used in the previous 3-months from a list of options. Questions also included asking “how many times in the previous 3-months” have you “talked about healthy sexual development or Child sexual abuse (CSA) with a child you know”; “suspected a child was sexually abused”; “taken steps to protect a child”; or “reported suspected sexual abuse to police or child welfare”? The majority of attendees were women, with the commonest age group being between 30 and 39 years old. Approximately 33% had experienced CSA themselves. At 3-month follow-up there were highly statistically significant improvements in several aspects of behavior and knowledge, and attitudes regarding CSA. For example, the number of subjects actively looking for evidence of CSA increased from 46% at baseline to 81% at follow-up, while the number of subjects who actively took steps to protect children increased from

  9. 76 FR 52378 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Featuring Selections From the National Museum of History, Taiwan and the Arthur M. Sackler Gallery... Jade Featuring Selections from the National Museum of History, Taiwan and the Arthur M. Sackler Gallery... Art, San Antonio, TX, from on or about October 1, 2011, until on or about February 19, 2012, and...

  10. 78 FR 25337 - Culturally Significant Object Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: April 15,...

  11. 77 FR 31909 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ....; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of...: 202- 632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  12. 78 FR 7849 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    .... 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and.... Department of State (telephone: 202- 632-6473). The mailing address is U.S. Department of State, SA-5,...

  13. 78 FR 50137 - Culturally Significant Objects Imported for Exhibition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ....; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of...: 202- 632-6469). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  14. Swamp to Space exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The menacing-looking alligator is really harmless. It is one of the realistic props to help convince visitors that the feel of the swamp is real in StenniSphere's Swamp to Space exhibit at John C. Stennis Space Center in Hancock County, Miss. The historical section of the Swamp to Space exhibit tells the story of why and how Stennis Space Center came to be. It also pays tribute to the families who moved their homes to make way for the space age in Mississippi.

  15. Pictures at an Exhibition.

    ERIC Educational Resources Information Center

    Kunz, Walter S., Jr.

    1997-01-01

    Describes the Youth Art Month exhibit in Howard County (Maryland) where students submitted their art focusing on school buildings and their interiors. Their art reveals concerns and desires about overcrowding, space utilization, school building height, outside lighting, solitude needs, and visual stimulation. The artwork is discussed in terms of…

  16. Exhibitions in Sight.

    ERIC Educational Resources Information Center

    Wasserman, Burton

    1978-01-01

    Early in the eighteenth century, Pompeii was discovered, a city that had been hidden for sixteen centuries by volcanic lava. There is a traveling exhibition of the sculptures, friezes, mosaics, and paintings being shown around the United States. Described is the history and contents of "Pompeii--A.D. 79." (RK)

  17. 1989 Architectural Exhibition Winners.

    ERIC Educational Resources Information Center

    School Business Affairs, 1990

    1990-01-01

    Winners of the 1989 Architectural Exhibition sponsored annually by the ASBO International's School Facilities Research Committee include the Brevard Performing Arts Center (Melbourne, Florida), the Capital High School (Santa Fe, New Mexico), Gage Elementary School (Rochester, Minnesota), the Lakewood (Ohio) High School Natatorium, and three other…

  18. Exhibition in Sight

    ERIC Educational Resources Information Center

    Wasserman, Burton

    1978-01-01

    Ludwig Mies van der Rohe is known primarily as an architect. However, he also designed chairs and tables. Discusses an exhibit held in New York City a few months ago which showed how well the famous architect achieved his goals in the area of furniture design. (Author/RK)

  19. The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia.

    PubMed

    Xiang, Lili; Li, Man; Liu, Yan; Cen, Jiangnong; Chen, Zixing; Zhen, Xiao; Xie, Xiaobao; Cao, Xiangshan; Gu, Weiying

    2013-08-01

    This study aimed to determine the clinical characteristics and prognostic significance of the meningioma 1 (MN1) gene and MN1-associated microRNA expression in Chinese adult de novo acute myeloid leukemia (AML) patients. The expression level of MN1, microRNA-20 (miR-20a), and microRNA-181b (miR-181b) in bone marrow mononuclear cells was measured in 158 newly diagnosed AML patients and 20 cases of normal healthy donors by real-time quantitative reverse transcriptase polymerase chain reaction. All AML patients significantly overexpressed MN1 at the level of 0.01983 (P < 0.001) compared with normal controls. High MN1 expression was associated with spleen involvement (P = 0.037), NPM1 wild type (P = 0.001), lower miR-20a expression levels (P = 0.015), and higher miR-181b expression levels (P = 0.035). MiR-20a (P = 0.029) and miR-181b (P = 0.017) overexpressed in the bone marrow cells of patients with certain subtypes of AML compared with healthy donors. High MN1 expressers had lower complete remission (CR) rates and shorter overall survival (OS) within the Southwest Oncology Group classification. In multivariable models, high MN1 expression was associated with worse CR rates (P = 0.01), relapse-free survival (RFS; P = 0.02), and OS (P = 0.02); high miR-20a expression was associated with higher CR rates (P = 0.008) and longer OS (P = 0.04), whereas high miR-181b expression was associated with lower CR rates (P = 0.03), and shorter RFS (P = 0.045) and OS (P = 0.017). High MN1 expression confers worse prognosis in Chinese adult patients with de novo AML. MN1 gene and MN1-associated microRNAs provide clinical prognosis of AML patients and may refine their molecular risk classification.

  20. Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia

    PubMed Central

    Mrózek, Krzysztof; Marcucci, Guido; Nicolet, Deedra; Maharry, Kati S.; Becker, Heiko; Whitman, Susan P.; Metzeler, Klaus H.; Schwind, Sebastian; Wu, Yue-Zhong; Kohlschmidt, Jessica; Pettenati, Mark J.; Heerema, Nyla A.; Block, AnneMarie W.; Patil, Shivanand R.; Baer, Maria R.; Kolitz, Jonathan E.; Moore, Joseph O.; Carroll, Andrew J.; Stone, Richard M.; Larson, Richard A.; Bloomfield, Clara D.

    2012-01-01

    Purpose To evaluate the prognostic significance of the international European LeukemiaNet (ELN) guidelines for reporting genetic alterations in acute myeloid leukemia (AML). Patients and Methods We analyzed 1,550 adults with primary AML, treated on Cancer and Leukemia Group B first-line trials, who had pretreatment cytogenetics and, for cytogenetically normal patients, mutational status of NPM1, CEBPA, and FLT3 available. We compared complete remission (CR) rates, disease-free survival (DFS), and overall survival (OS) among patients classified into the four ELN genetic groups (favorable, intermediate-I, intermediate-II, adverse) separately for 818 younger (age < 60 years) and 732 older (age ≥ 60 years) patients. Results The percentages of younger versus older patients in the favorable (41% v 20%; P < .001), intermediate-II (19% v 30%; P < .001), and adverse (22% v 31%; P < .001) genetic groups differed. The favorable group had the best and the adverse group the worst CR rates, DFS, and OS in both age groups. Both intermediate groups had significantly worse outcomes than the favorable but better than the adverse group. Intermediate-I and intermediate-II groups in older patients had similar outcomes, whereas the intermediate-II group in younger patients had better OS but not better CR rates or DFS than the intermediate-I group. The prognostic significance of ELN classification was confirmed by multivariable analyses. For each ELN group, older patients had worse outcomes than younger patients. Conclusion The ELN classification clearly separates the genetic groups by outcome, supporting its use for risk stratification in clinical trials. Because they have different proportions of genetic alterations and outcomes, younger and older patients should be reported separately when using the ELN classification. PMID:22987078

  1. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This photograph shows the Starship 2040 leaving the Marshall Space Flight Center (MSFC) for the exhibit site. Developed by the Space Transportation Directorate at MSFC, the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit, automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids and emergency and safety systems, are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  2. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows onlookers viewing displays within the Starship 2040 exhibit on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  3. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows Justin Varnadore, son of a Marshall TV employee, at the controls of one of the many displays within the Starship 2040 exhibit on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  4. Online Exhibits & Concept Maps

    NASA Astrophysics Data System (ADS)

    Douma, M.

    2009-12-01

    Presenting the complexity of geosciences to the public via the Internet poses a number of challenges. For example, utilizing various - and sometimes redundant - Web 2.0 tools can quickly devour limited time. Do you tweet? Do you write press releases? Do you create an exhibit or concept map? The presentation will provide participants with a context for utilizing Web 2.0 tools by briefly highlighting methods of online scientific communication across several dimensions. It will address issues of: * breadth and depth (e.g. from narrow topics to well-rounded views), * presentation methods (e.g. from text to multimedia, from momentary to enduring), * sources and audiences (e.g. for experts or for the public, content developed by producers to that developed by users), * content display (e.g. from linear to non-linear, from instructive to entertaining), * barriers to entry (e.g. from an incumbent advantage to neophyte accessible, from amateur to professional), * cost and reach (e.g. from cheap to expensive), and * impact (e.g. the amount learned, from anonymity to brand awareness). Against this backdrop, the presentation will provide an overview of two methods of online information dissemination, exhibits and concept maps, using the WebExhibits online museum (www.webexhibits.org) and SpicyNodes information visualization tool (www.spicynodes.org) as examples, with tips on how geoscientists can use either to communicate their science. Richly interactive online exhibits can serve to engage a large audience, appeal to visitors with multiple learning styles, prompt exploration and discovery, and present a topic’s breadth and depth. WebExhibits, which was among the first online museums, delivers interactive information, virtual experiments, and hands-on activities to the public. While large, multidisciplinary exhibits on topics like “Color Vision and Art” or “Calendars Through the Ages” require teams of scholars, user interface experts, professional writers and editors

  5. HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infection.

    PubMed

    Chijioke-Nwauche, Ifeyinwa; van Wyk, Albert; Nwauche, Chijioke; Beshir, Khalid B; Kaur, Harparkash; Sutherland, Colin J

    2013-09-01

    Management of coinfection with malaria and HIV is a major challenge to public health in developing countries, and yet potential drug-drug interactions between antimalarial and antiviral regimens have not been adequately investigated in people with both infections. Each of the constituent components of artemether-lumefantrine, the first-line regimen for malaria treatment in Nigeria, and nevirapine, a major component of highly active antiretroviral therapy, are drugs metabolized by the cytochrome P450 3A4 isoenzyme system, which is also known to be induced by nevirapine. We examined potential interactions between lumefantrine and nevirapine in 68 HIV-positive adults, all of whom were diagnosed with asymptomatic Plasmodium falciparum infections by microscopy. Post hoc PCR analysis confirmed the presence of P. falciparum in only a minority of participants. Day 7 capillary blood levels of lumefantrine were significantly higher in HIV-positive participants than in 99 HIV-negative controls (P = 0.0011). Associations between day 7 levels of lumefantrine and risk of persistent parasitemia could not be evaluated due to inadequate power. Further investigations of the impact of nevirapine on in vivo malaria treatment outcomes in HIV-infected patients are thus needed.

  6. Consumption of a healthy dietary pattern results in significant reductions in C-reactive protein levels in adults: a meta-analysis.

    PubMed

    Neale, E P; Batterham, M J; Tapsell, L C

    2016-05-01

    Consumption of healthy dietary patterns has been associated with reduced risk of cardiovascular disease and metabolic syndrome. Dietary intervention targets disease prevention, so studies increasingly use biomarkers of underlying inflammation and metabolic syndrome progression to examine the diet-health relationship. The extent to which these biomarkers contribute to the body of evidence on healthy dietary patterns is unknown. The aim of this meta-analysis was to determine the effect of healthy dietary patterns on biomarkers associated with adiposity, insulin resistance, and inflammation in adults. A systematic search of Scopus, PubMed, Web of Science, and Cochrane Central Register of Controlled Trials (all years to April 2015) was conducted. Inclusion criteria were randomized controlled trials; effects of dietary patterns assessed on C-reactive protein (CRP), total adiponectin, high-molecular-weight adiponectin, tumor necrosis factor-α, adiponectin:leptin, resistin, or retinol binding protein 4. Random effects meta-analyses were conducted to assess the weighted mean differences in change or final mean values for each outcome. Seventeen studies were included in the review. These reflected research on dietary patterns associated with the Mediterranean diet, Nordic diet, Tibetan diet, and the Dietary Approaches to Stop Hypertension diet. Consumption of a healthy dietary pattern was associated with significant reductions in CRP (weighted mean difference, -0.75 [-1.16, -0.35]; P = .0003). Non-significant changes were found for all other biomarkers. This analysis found evidence for favorable effects of healthy dietary patterns on CRP, with limited evidence for other biomarkers. Future research should include additional randomized controlled trials incorporating a greater range of dietary patterns and biomarkers.

  7. Space Shuttle Cockpit exhibit

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Want to sit in the cockpit of the Space Shuttle and watch astronauts work in outer space? At StenniSphere, you can do that and much more. StenniSphere, the visitor center at John C. Stennis Space Center in Hancock County, Miss., presents 14,000-square-feet of interactive exhibits that depict America's race for space as well as a glimpse of the future. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  8. Starship 2040 Exhibit

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This photograph shows the Starship 2040 on display at Joe Davis Stadium in Huntsville, Alabama. Developed by the Space Transportation Directorate at Marshall Space Flight Center (MSFC), the Starship 2040 exhibit is housed in a 48-ft (14.6-m) tractor and trailer rig, permitting it to travel around the Nation, demonstrating NASA's vision of what commercial spaceflight might be like 40 years from now. All the irnovations suggested aboard the exhibit (automated vehicle health monitoring systems, high-energy propulsion drive, navigational aids, and emergency and safety systems) are based on concepts and technologies now being studied at NASA Centers and partner institutions around the Nation. NASA is the Nation's premier agency for development of the space transportation system, including future-generation reusable launch vehicles. Such systems, the keys to a 'real' Starship 2040, require revolutionary advances in critical aerospace technologies, from thermal, magnetic, chemical, and propellantless propulsion systems to new energy sources such as space solar power or antimatter propulsion. These and other advances are now being studied, developed, and tested at NASA field centers and partner institutions all over the Nation.

  9. Significant long-term, but not short-term, hippocampal-dependent memory impairment in adult rats exposed to alcohol in early postnatal life.

    PubMed

    Goodfellow, Molly J; Lindquist, Derick H

    2014-09-01

    In rodents, ethanol exposure in early postnatal life is known to induce structural and functional impairments throughout the brain, including the hippocampus. Herein, rat pups were administered one of three ethanol doses over postnatal days (PD) 4-9, a period of brain development comparable to the third trimester of human pregnancy. As adults, control and ethanol rats were trained and tested in a variant of hippocampal-dependent one-trial context fear conditioning. In Experiment 1, subjects were placed into a novel context and presented with an immediate footshock (i.e., within ∼8 sec). When re-exposed to the same context 24 hr later low levels of conditioned freezing were observed. Context pre-exposure 24 hr prior to the immediate shock reversed the deficit in sham-intubated and unintubated control rats, enhancing freezing behavior during the context retention test. Even with context pre-exposure, however, significant dose-dependent reductions in contextual freezing were seen in ethanol rats. In Experiment 2, the interval between context pre-exposure and the immediate shock was shortened to 2 hr, in addition to the standard 24 hr. Ethanol rats trained with the 2 hr, but not 24 hr, interval displayed retention test freezing levels roughly equal to controls. Results suggest the ethanol rats can encode a short-term context memory and associate it with the aversive footshock 2 hr later. In the 24 hr ethanol rats the short-term context memory is poorly transferred or consolidated into long-term memory, we propose, impeding the memory's subsequent retrieval and association with shock.

  10. Sex-comparative study of mouse cerebellum physiology under adult-onset hypothyroidism: The significance of GC-MS metabolomic data normalization in meta-analysis.

    PubMed

    Maga-Nteve, Christoniki; Vasilopoulou, Catherine G; Constantinou, Caterina; Margarity, Marigoula; Klapa, Maria I

    2017-01-15

    A systematic data quality validation and normalization strategy is an important component of the omic profile meta-analysis, ensuring comparability of the profiles and exclusion of experimental biases from the derived biological conclusions. In this study, we present the normalization methodology applied on the sets of cerebellum gas chromatography-mass spectrometry metabolic profiles of 124days old male and female animals in an adult-onset-hypothyroidism (AOH) mouse model before combining them into a sex-comparative analysis. The employed AOH model concerns the monitoring of the brain physiology of Balb/cJ mice after eight-week administration of 1%w/v KClO4 in the drinking water, initiated on the 60th day of their life. While originating from the same animal study, the tissues of the two sexes were processed and their profiles acquired and analyzed at different time periods. Hence, the previously published profile set of male mice was first re-annotated based on the presently available resources. Then, after being validated as acquired under the same analytical conditions, both profiles sets were corrected for derivatization biases and filtered for low-confidence measurements based on the same criteria. The final normalized 73-metabolite profiles contribute to the currently few available omic datasets of the AOH effect on brain molecular physiology, especially with respect to sex differentiation. Multivariate statistical analysis indicated one (unknown) and three (succinate, benzoate, myristate) metabolites with significantly higher and lower, respectively, cerebellum concentration in the hypothyroid compared to the euthyroid female mice. The respective numbers for the males were two and 24. Comparison of the euthyroid cerebellum metabolic profiles between the two sexes indicated 36 metabolites, including glucose, myo- and scyllo-inositol, with significantly lower concentration in the females versus the males. This implies that the female mouse cerebellum has been

  11. Sex differences in science museum exhibit attraction

    NASA Astrophysics Data System (ADS)

    Arámbula Greenfield, Teresa

    This study examines the relative attraction of hands-on, interactive science museum exhibits for females and males. Studies have demonstrated that such exhibits can be effective learning experiences for children, with both academic and affective benefits. Other studies have shown that girls and boys do not always experience the same science-related educational opportunities and that, even when they do, they do not necessarily receive the same benefits from them. These early differences can lead to more serious educational and professional disparities later in life. As interactive museum exhibits represent a science experience that is-readily available to both girls and boys, the question arose as to whether they were being used similarly by the two groups as well as by adult women and men. It was found that both girls and boys used all types of exhibits, but that girls were more likely than boys to use puzzles and exhibits focusing on the human body; boys were more likely than girls to use computers and exhibits illustrating physical science principles. However, this was less true of children accompanied by adults (parents) than it was of unaccompanied children on school field trips who roamed the museum more freely.Received: 16 February 1994; Revised: 3 February 1995;

  12. Prognostic significance of bcl-2 protein expression in aggressive non-Hodgkin's lymphoma. Groupe d'Etude des Lymphomes de l'Adulte (GELA).

    PubMed

    Hermine, O; Haioun, C; Lepage, E; d'Agay, M F; Briere, J; Lavignac, C; Fillet, G; Salles, G; Marolleau, J P; Diebold, J; Reyas, F; Gaulard, P

    1996-01-01

    Little is known about the expression of bcl-2 protein in intermediate and high grade non-Hodgkin's lymphoma (NHL) and its clinical and prognostic significance. We performed immunohistochemical analysis of bcl-2 expression in tumoral tissue sections of 348 patients with high or intermediate grade NHL. These patients were uniformly treated with adriamycin, cyclophosphamide, vindesine, bleomycin, and prednisone (ACVBP) in the induction phase of the LNH87 protocol. Fifty eight cases were excluded due to inadequate staining. Of the 290 remaining patients, 131 (45%) disclosed homogeneous positivity (high bcl-2 expression) in virtually all tumor cells, whereas 65 (23%) were negative and 94 (32%) exhibited intermediate staining. High bcl-2 expression was more frequent in B-cell NHL (109 of 214, 51%) than in T-cell NHL (6 of 35, 17%) (P = .0004), and was heterogeneously distributed among the different histological subtypes. Further analysis was performed on the 151 patients with diffuse large B-cell lymphoma (centroblastic and immunoblastic) to assess the clinical significance and potential prognostic value of bcl-2 expression in the most frequent and homogeneous immunohistological subgroup. High bcl-2 expression, found in 44% of these patients (67 of 151), was more frequently associated with III-IV stage disease (P = .002). Reduced disease-free survival (DFS) (P < .01) and overall survival (P < .05) were demonstrated in the patients with high bcl-2 expression. Indeed, the 3-year estimates of DFS and overall survival were 60% and 61%, respectively (high bcl-2 expression) versus 82% and 78%, respectively (negative/intermediate bcl-2 expression). A multivariate regression analysis confirmed the independent effect of bcl-2 protein expression on DFS. Thus bcl-2 protein expression, as demonstrated in routinely paraffin-embedded tissue, appears to be predictive of poor DFS, in agreement with the role of bcl-2 in chemotherapy-induced apoptosis. It might be considered as a new

  13. Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline.

    PubMed

    Shah, Tejal M; Weinborn, Michael; Verdile, Giuseppe; Sohrabi, Hamid R; Martins, Ralph N

    2017-03-01

    Successfully assisting older adults to maintain or improve cognitive function, particularly when they are dealing with neurodegenerative disorders such as Alzheimer's disease (AD), remains a major challenge. Cognitive training may stimulate neuroplasticity thereby increasing cognitive and brain reserve. Commercial brain training programs are computerized, readily-available, easy-to-administer and adaptive but often lack supportive data and their clinical validation literature has not been previously reviewed. Therefore, in this review, we report the characteristics of commercially available brain training programs, critically assess the number and quality of studies evaluating the empirical evidence of these programs for promoting brain health in healthy older adults, and discuss underlying causal mechanisms. We searched PubMed, Google Scholar and each program's website for relevant studies reporting the effects of computerized cognitive training on cognitively healthy older adults. The evidence for each program was assessed via the number and quality (PEDro score) of studies, including Randomized Control Trials (RCTs). Programs with clinical studies were subsequently classified as possessing Level I, II or III evidence. Out of 18 identified programs, 7 programs were investigated in 26 studies including follow-ups. Two programs were identified as possessing Level I evidence, three programs demonstrated Level II evidence and an additional two programs demonstrated Level III evidence. Overall, studies showed generally high methodological quality (average PEDro score = 7.05). Although caution must be taken regarding any potential bias due to selective reporting, current evidence supports that at least some commercially available computerized brain training products can assist in promoting healthy brain aging.

  14. Enhancing the passing moments: An educational criticism of family visits to an early childhood science exhibition

    NASA Astrophysics Data System (ADS)

    Munroe, Elizabeth Ann

    This educational criticism describes and interprets the nature of family visits to an early childhood science exhibition, Working Wonders, at The Science Centre in Calgary, Alberta. The specific exhibits are described and features that contributed to exhibit popularity are examined. Examples of visitors' interactions with each exhibit are given. The visit experiences of four families are described in detail and analyzed. Typical family visitors' reactions, expectations, and experiences are summarized. Because one of the mutual expectations of the granting agency, The Science Centre, and the adult visitors was that a visit to the exhibition would be educational, the family visits are examined for instances of learning and analyzed to determine the factors that influenced the learning. Constructivism forms the basis for understanding the process of learning during family visits. The analysis is supported by reference to research from the fields of museum studies, education, and environmental design. The analysis of the educational significance and potential of family visits to an early childhood exhibition leads to the conclusion that specific features may facilitate learning in such an environment. Those features are represented in a set of guidelines for the development and evaluation of early childhood exhibitions. The guidelines suggest attention must be given to the ambience of the space, the general layout of the space, the exhibits, the copy and graphics, additional programs and information, the subtle influences of the building and the staff, and the learning processes of young children, adults, and intergenerational groups. The guidelines suggest specific issues to consider to develop a space that is stimulating and memorable, responsive to the needs of the two distinct visitor groups (young children and adults), and conducive to learning.

  15. Traveling Exhibitions: translating current science into effective science exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, P.; Morrow, C.; Harold, J.

    The Space Science Institute (SSI) of Boulder, Colorado has recently developed two museum exhibits called the Space Weather Center and MarsQuest. It is currently planning to develop two other exhibitions called Cosmic Origins and InterActive Earth. Museum exhibitions provide research scientists the opportunity to engage in a number of activities that are vital to the success of earth and space outreach programs. The Space Weather Center was developed in partnership with various research missions at NASA's Goddard Space Flight Center. The focus of the presentation will be on the Institute's MarsQuest exhibition. This project is a 5000 square-foot, 2.5M, traveling exhibition that is now touring the country. The exhibit's 3-year tour is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and learn more about their own planet in the process. The associated planetarium show and education program will also be described, with particular emphasis on workshops to orient host museum staff (e.g. museum educators and docents). The workshops make innovative connections between the exhibitions interactive experiences and lesson plans aligned with the National Science Education Standards. SSI is also developing an interactive web site called MarsQuest On-line. The linkage between the web site, education program and exhibit will be discussed. MarsQuest and SSI's other exhibitions are good models for actively involving scientists and their discoveries to help improve informal science education in the museum community and for forging a stronger connection between formal and informal education.

  16. Environmental enrichment for a mixed-species nocturnal mammal exhibit.

    PubMed

    Clark, Fay E; Melfi, Vicky A

    2012-01-01

    Environmental enrichment (EE) is an integral aspect of modern zoo animal management but, empirical evaluation of it is biased toward species housed in single-species groups. Nocturnal houses, where several nocturnal species are housed together, are particularly overlooked. This study investigated whether three species (nine-banded armadillos, Dasypus novemcinctus; Senegal bush babies, Galago senegalensis; two-toed sloths, Choloepus didactylus) in the nocturnal house at Paignton Zoo Environmental Park, UK could be enriched using food-based and sensory EE. Subjects were an adult male and female of each species. EE was deemed effective if it promoted target species-typical behaviors, behavioral diversity, and increased use of enriched exhibit zones. Results from generalized linear mixed models demonstrated that food-based EE elicited the most positive behavioral effects across species. One set of food-based EEs (Kong®, termite mound and hanging food) presented together was associated with a significant increase in species-typical behaviors, increased behavioral diversity, and increased use of enriched exhibit zones in armadillos and bush babies. Although one type of sensory EE (scented pine cones) increased overall exhibit use in all species, the other (rainforest sounds) was linked to a significant decrease in species-typical behavior in bush babies and sloths. There were no intra or interspecies conflicts over EE, and commensalism occurred between armadillos and bush babies. Our data demonstrate that simple food-based and sensory EE can promote positive behavioral changes in a mixed-species nocturnal mammal exhibit. We suggest that both food and sensory EE presented concurrently will maximize opportunities for naturalistic activity in all species.

  17. Dipstick proteinuria level is significantly associated with pre-morbid and in-hospital functional status among hospitalized older adults: a preliminary study

    PubMed Central

    Chao, Chia-Ter; Tsai, Hung-Bin; Chiang, Chih-Kang; Huang, Jenq-Wen; Hung, Kuan-Yu

    2017-01-01

    Although chronic kidney disease (CKD) is associated with functional decline, whether proteinuria alone is associated with functional statuses over the course of acute illnesses independent of CKD is unclear. During 2014, we prospectively enrolled non-dialysis patients aged ≥65 years, and all participants underwent spot dipstick urinalysis on admission, divided into 3 groups according to the results (none, trace to 1 + , and 2 + or higher); functional status was evaluated using the pre-morbid and in-hospital Barthel index (BI) scores. Of 136 community-dwelling elderly patients enrolled (age 80.7 ± 8.2 years, with 19% having CKD), 17%, 57%, and 26% had no, trace to 1 + , or 2 + or higher proteinuria. Overall pre-morbid, on-admission, and on-discharge BI scores were 50.4 ± 41.9, 38.6 ± 31.8, and 38.7 ± 35.3, respectively with significant negative correlations with proteinuric severity on admission. Finally, multivariate linear stepwise regression analysis with backward variable selection found that dipstick proteinuric severity was significantly associated with pre-morbid, on-admission, and on-dischrage BI scores (p = 0.048, <0.01, and <0.01, respectively), independent of diabetes and CKD. This relationship between dipstick proteinuric levels and functional status of hospitalized elderly suggests an under-recognized association. Prospective evaluation of long-term outcome is needed. PMID:28176820

  18. Prognostic significance of Epstein-Barr virus in nodal peripheral T-cell lymphoma, unspecified: A Groupe d'Etude des Lymphomes de l'Adulte (GELA) study.

    PubMed

    Dupuis, Jehan; Emile, Jean-François; Mounier, Nicolas; Gisselbrecht, Christian; Martin-Garcia, Nadine; Petrella, Tony; Bouabdallah, Reda; Berger, Françoise; Delmer, Alain; Coiffier, Bertrand; Reyes, Félix; Gaulard, Philippe

    2006-12-15

    Peripheral T-cell lymphomas (PTCLs) are rare and have a dismal prognosis. The most frequent subtype is PTCL, unspecified. Epstein-Barr virus (EBV) has been detected in around 40% of cases, but its prognostic significance is not fully established. Lymph node samples from 110 patients with PTCL, unspecified included in LNH87 and LNH93 trials were available. EBV status was studied by EBV-encoded small RNA in situ hybridization (EBER-ISH). EBER-ISH showed positive cells in 45 (41%) of 110 patients. Pretreatment characteristics were comparable between positive and negative cases, except for male sex (80% versus 60%, respectively, P = .02). Only 50% of patients achieved complete remission with a 5-year event-free survival (EFS) and overall survival (OS) of 21% and 30%, respectively. EBER-ISH positivity was the sole factor linked with worse EFS, with a 5-year probability of 11% for positive patients. In univariate analysis, factors affecting OS were EBER-ISH positivity, high LDH level, and age older than 60 years. In multivariate analysis, EBER-ISH was associated with a worse OS in the elderly population. Time-dependent analysis showed that the negative impact of EBV was essentially seen in the first 2 years following diagnosis. These results warrant further studies regarding pathogenesis and specific treatment approaches for EBV-associated PTCL patients.

  19. Prognostic significance of T-cell phenotype in aggressive non-Hodgkin's lymphomas. Groupe d'Etudes des Lymphomes de l'Adulte (GELA).

    PubMed

    Gisselbrecht, C; Gaulard, P; Lepage, E; Coiffier, B; Brière, J; Haioun, C; Cazals-Hatem, D; Bosly, A; Xerri, L; Tilly, H; Berger, F; Bouhabdallah, R; Diebold, J

    1998-07-01

    Peripheral T-cell lymphomas (PTCL) have been generally reported to have a worse prognosis than B-cell lymphomas (BCL). Because of their heterogeneity and scarcity, the outcomes of the different histological subtypes have not been compared. From October 1987 to March 1993, 1,883 patients with diffuse aggressive non-Hodgkin's lymphomas (NHL) included in the LNH87 protocol could be assessed for both morphology and immunophenotyping. Among them, 288 (15%) had PTCL and 1,595 (85%) had BCL. According to the Kiel classification, most PTCL were classified as angioimmunoblastic (AIL; 23%), pleomorphic medium and large T-cell (PML; 49%), or anaplastic large cell (ALCL; 20%) lymphomas. Comparing PTCL with BCL patients, the former had more disseminated disease (78% v 58%), B symptoms (57% v 40%), bone marrow involvement (31% v 17%), skin involvement (21% v 4%), and increased beta2-microglobulin (50% v 34%), whereas BCL patients had more bulky disease (41% v 26%). According to the International Prognostic Index (IPI), PTCL and BCL scores were, respectively: 0 factors, 13% and 15%; 1 factor, 17% and 22%; 2 factors, 24% and 25%; >/=3 factors, 45% and 37% (P = .09). For BCL and PTCL, respectively, complete remission rates were 63% and 54% (P = .004); the 5-year overall survival (OS) rates were 53% and 41% (P = .0004) and event-free survival (EFS) rates were 42% and 33% (P < . 0001). Comparison of the different histological subtypes of lymphoma showed that the 5-year OS rate for T-ALCL (64%) was superior to those of other PTCL (35%) as well as diffuse large B-cell (53%) NHL. When multivariate analysis was applied using the IPI score as one factor, nonanaplastic PTCL remained an independent parameter (P = . 0004). Although the poor prognosis of non-ALCL PTCL could be due in part to the presence of adverse prognostic factors at diagnosis, this study shows that the T-cell phenotype is an independent significant factor, which should be incorporated into the definition of prognostic

  20. Helicobacter pylori infection has no impact on manometric and pH-metric findings in adolescents and young adults with gastroesophageal reflux and antral gastritis: eradication results to no significant clinical improvement.

    PubMed

    Xinias, Ioannis; Maris, Theophanis; Mavroudi, Antigoni; Panteliadis, Christos; Vandenplas, Yvan

    2013-02-05

    The relationship between Helicobacter pylori (Hp) gastritis and gastroesophageal reflux disease (GERD) remains controversial. The aim was to investigate the association between Hp infection and gastroesophageal reflux (GER) and the impact of Hp eradication on esophageal acid exposure and motility in adolescents and young adults with Hp gastritis and GERD. Sixty-four patients with symptoms suggestive for GERD, of which 40 Hp-positive (group A) and 24 Hp-negative (group B), underwent endoscopy-biopsy, esophageal manometry and 24-hour pH-metry. All group A patients received eradication treatment and were re-evaluated six months later again with 24-hour pH-metry, esophageal manometry, endoscopy-biopsy and clinical assessment. At inclusion, there were no significant differences between the two groups regarding sex, age, grade of endoscopic esophagitis, manometric and pH-metry findings. All Hp-positive patients had an antral predominant gastritis. Eradication of Hp was successful in all patients, and gastritis and esophagitis were healed in all patients. The mean lower esophageal sphincter pressure (LESP) increased significantly from 11.25 mmHg before to 11.71 mmHg after eradication (P<0.05). A significant decrease in reflux index was observed (mean RI 6.02% before versus 4.96% after eradication (P<0.05). However clinical symptoms of GER improved not significantly after 6 months follow up. Conclusively, in children and young adults with GER symptoms and GERD, the presence or absence of Hp has no impact on manometric and pH-metric findings. Eradication of Hp infection results in increase in LESP with a consequent decrease in esophageal acid exposure but not significant clinical improvement.

  1. Communicating Complex Sciences by Means of Exhibitions

    NASA Astrophysics Data System (ADS)

    Schneider, S.

    2011-12-01

    Earth Sciences will have to take over the leading role in global sustainable policy and in discussions about climate change. Efforts to raise attention within the politically responsible communities as well as in the public are getting more and more support by executive and advisory boards all over the world. But how can you successfully communicate complex sciences? For example, to start communication about climate change, the first step is to encourage people to be concerned about climate change. After that, one has to start thinking about how to present data and how to include the presented data into an unprejudiced context. Therefore, the communication toolbox offers various methods to reach diverse audiences. The R&D programme GEOTECHNOLOGIEN conducts roving exhibitions as one of its most successful communication tools. With roving exhibitions GEOTECHNOLOGIEN is able to get in touch with different audiences at once. The main purpose and theme of these exhibitions is to convey the everyday means of climate change to the visitors. It is within the responsibility of science to communicate the effects of a phenomenon like climate change as well as the impact of research results to the everyday life of people. Currently, a GEOTECHNOLOGIEN roving exhibition on remote sensing with satellites deals with various issues of environmental research, including a chapter on climate change. By following the 3M-concept (Meaning - Memorable - Moving), exhibitions allow to connect the visitors daily environment and personal experiences with the presented issues and objects. Therefore, hands-on exhibits, exciting multimedia effects and high-tech artefacts have to be combined with interpretive text elements to highlight the daily significance of the scientific topics and the exhibition theme respectively. To create such an exhibition, strong conceptual planning has to be conducted. This includes the specification of stern financial as well as time wise milestones. In addition

  2. The clinical characteristics and prognostic significance of AID, miR-181b, and miR-155 expression in adult patients with de novo B-cell acute lymphoblastic leukemia.

    PubMed

    Zhou, Guangquan; Cao, Yang; Dong, Weimin; Lin, Yan; Wang, Qi; Wu, Wei; Hua, Xiaoying; Ling, Yun; Xie, Xiaobao; Hu, Shaoyan; Cen, Jiannong; Gu, Weiying

    2017-01-31

    This study aimed to investigate clinical characteristics and prognostic significance of activation-induced cytidine deaminase (AID) gene, miR-181b and miR-155 expression in de novo adult B-cell acute lymphoblastic leukemia (B-ALL) patients. Results showed that AID and miR-155 expression were higher in B-ALL patients than healthy controls, while miR-181b expression was lower in B-ALL patients. In addition, Ph(+) B-ALLs had higher AID expression than Ph(-) B-ALLs, and its high expression was associated with BCR-ABL. Moreover, B-ALL patients with AID(high) or miR-181b(low) expression had a shorter overall survival (OS). AID(high) with miR-181b(low), AID(high) with miR-155(low), miR-181b(low), miR-155(low), AID(high) with miR-181b(low) and miR-155(low) expression were associated with shorter OS. Combination of the three molecules are more accurate predictors for unfavorable OS compared with univariate group. Therefore, AID, miR-181b and miR-155 provide clinical prognosis of adult de novo B-ALL patients and may refine their molecular risk classification.

  3. Psychological resources of adults with developmental dyslexia.

    PubMed

    Łockiewicz, Marta; Bogdanowicz, Katarzyna M; Bogdanowicz, Marta

    2014-01-01

    The aim of our study was to describe specific psychological resources of adults with developmental dyslexia and compare them with psychological resources of adults without developmental dyslexia. Potential differences were analyzed in visual-spatial, creative, and motivational abilities. No evidence was found for either creative, or visuospatial superiority in adults with developmental dyslexia. The results suggest, however, that visual-spatial processing of nonverbal material by adults with developmental dyslexia allows them to efficiently execute tasks that are based on sequential material. Moreover, the participants with specific difficulties in reading and writing exhibited a significantly higher level of aspirations than their peers without such difficulties with a comparable level of educational achievement. These results suggest that succeeding in different fields by highly functioning adult dyslexics may depend on personality and motivational factors, rather than cognitive factors.

  4. Thermoelectric device exhibiting decreased stress

    SciTech Connect

    Heath, D.L.; Chou, D.J.

    1985-02-05

    A thermoelectric device exhibiting both structural integrity and decreased stress across the device notwithstanding the application of thermally cycled temperature differentials thereacross includes, electrically interconnected thermoelectric elements and a rigidly affixed substrate. Thermal stress is relieved by using flexible conductors to interconnect the thermoelectric elements, and by the use of a flexile joint to attach a second substrate to the remainder of the device. Complete elimination of the second substrate may also be used to eliminate stress. Presence of the rigidly affixed substrate gives the device sufficient structural integrity to enable it to withstand rugged conditions.

  5. Large holograms in traveling exhibitions

    NASA Astrophysics Data System (ADS)

    Christakis, Anne-Marie

    1994-01-01

    The presentation of large holograms in travelling exhibitions has always posed problems, mainly due to lack of space. The Museum of Holography was consequently required to develop, with Jean-Francois Moreau, display consoles which are light, affordable and completely detachable. In a permanent exposition at the Forum des Halles in Paris, the Museum displays a room with 22 holograms, each measuring 1 m X 1 m, in a structure designed by the architect Fabien Vienne. The different systems used by the Museum are presented here.

  6. Collaborative virtual environments art exhibition

    NASA Astrophysics Data System (ADS)

    Dolinsky, Margaret; Anstey, Josephine; Pape, Dave E.; Aguilera, Julieta C.; Kostis, Helen-Nicole; Tsoupikova, Daria

    2005-03-01

    This panel presentation will exhibit artwork developed in CAVEs and discuss how art methodologies enhance the science of VR through collaboration, interaction and aesthetics. Artists and scientists work alongside one another to expand scientific research and artistic expression and are motivated by exhibiting collaborative virtual environments. Looking towards the arts, such as painting and sculpture, computer graphics captures a visual tradition. Virtual reality expands this tradition to not only what we face, but to what surrounds us and even what responds to our body and its gestures. Art making that once was isolated to the static frame and an optimal point of view is now out and about, in fully immersive mode within CAVEs. Art knowledge is a guide to how the aesthetics of 2D and 3D worlds affect, transform, and influence the social, intellectual and physical condition of the human body through attention to psychology, spiritual thinking, education, and cognition. The psychological interacts with the physical in the virtual in such a way that each facilitates, enhances and extends the other, culminating in a "go together" world. Attention to sharing art experience across high-speed networks introduces a dimension of liveliness and aliveness when we "become virtual" in real time with others.

  7. Neural correlates of letter reversal in children and adults.

    PubMed

    Blackburne, Liwei King; Eddy, Marianna D; Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D E

    2014-01-01

    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging) and the electrophysiological correlates (via event-related potentials or ERPs) of this phenomenon in children, ages 5-12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA) in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing.

  8. Children do not exhibit ambiguity aversion despite intact familiarity bias.

    PubMed

    Li, Rosa; Brannon, Elizabeth M; Huettel, Scott A

    2014-01-01

    The phenomenon of ambiguity aversion, in which risky gambles with known probabilities are preferred over ambiguous gambles with unknown probabilities, has been thoroughly documented in adults but never measured in children. Here, we use two distinct tasks to investigate ambiguity preferences of children (8- to 9-year-olds) and a comparison group of adults (19- to 27-year-olds). Across three separate measures, we found evidence for significant ambiguity aversion in adults but not in children and for greater ambiguity aversion in adults compared to children. As ambiguity aversion in adults has been theorized to result from a preference to bet on the known and avoid the unfamiliar, we separately measured familiarity bias and found that children, like adults, are biased towards the familiar. Our findings indicate that ambiguity aversion emerges across the course of development between childhood and adolescence, while a familiarity bias is already present in childhood.

  9. Children do not exhibit ambiguity aversion despite intact familiarity bias

    PubMed Central

    Li, Rosa; Brannon, Elizabeth M.; Huettel, Scott A.

    2015-01-01

    The phenomenon of ambiguity aversion, in which risky gambles with known probabilities are preferred over ambiguous gambles with unknown probabilities, has been thoroughly documented in adults but never measured in children. Here, we use two distinct tasks to investigate ambiguity preferences of children (8- to 9-year-olds) and a comparison group of adults (19- to 27-year-olds). Across three separate measures, we found evidence for significant ambiguity aversion in adults but not in children and for greater ambiguity aversion in adults compared to children. As ambiguity aversion in adults has been theorized to result from a preference to bet on the known and avoid the unfamiliar, we separately measured familiarity bias and found that children, like adults, are biased towards the familiar. Our findings indicate that ambiguity aversion emerges across the course of development between childhood and adolescence, while a familiarity bias is already present in childhood. PMID:25601848

  10. Exhibits Enhanced by Stand-Alone Computers.

    ERIC Educational Resources Information Center

    Van Rennes, Eve C.

    Both the development and evaluation of one of a set of computer programs designed for use by visitors as adjuncts to museum exhibits are described. Museum displays used were (1) a static, behind-glass exhibit on evolution; (2) a hands-on primitive stone age tools exhibit; and (3) a Foucault pendulum. A computer placed next to each exhibit served…

  11. Modelling the Future: Exhibitions and the Materiality of Education

    ERIC Educational Resources Information Center

    Lawn, Martin, Ed.

    2009-01-01

    The role of World Exhibitions in the 19th and early 20th centuries was to confirm a relation between the nation state and modernity. As a display about industries, inventions and identities, the Exhibition, in a sense, put entire nations into an elevated, viewable space. It is a significant element in modernity as comparisons can be made, progress…

  12. A Critical Appraisal of State Level Science Exhibition

    ERIC Educational Resources Information Center

    Nath, Baiju K.

    2007-01-01

    Science exhibitions are really great opportunities to students as well as teachers to disseminate knowledge that they have, and to experience a variety of new inventions and innovations that also need wide dissemination. The great significance of exhibition is that it fosters acquisition of different process skills leading to the development of…

  13. Supercomputing meets seismology in earthquake exhibit

    ScienceCinema

    Blackwell, Matt; Rodger, Arthur; Kennedy, Tom

    2016-07-12

    When the California Academy of Sciences created the "Earthquake: Evidence of a Restless Planet" exhibit, they called on Lawrence Livermore to help combine seismic research with the latest data-driven visualization techniques. The outcome is a series of striking visualizations of earthquakes, tsunamis and tectonic plate evolution. Seismic-wave research is a core competency at Livermore. While most often associated with earthquakes, the research has many other applications of national interest, such as nuclear explosion monitoring, explosion forensics, energy exploration, and seismic acoustics. For the Academy effort, Livermore researchers simulated the San Andreas and Hayward fault events at high resolutions. Such calculations require significant computational resources. To simulate the 1906 earthquake, for instance, visualizing 125 seconds of ground motion required over 1 billion grid points, 10,000 time steps, and 7.5 hours of processor time on 2,048 cores of Livermore's Sierra machine.

  14. Supercomputing meets seismology in earthquake exhibit

    SciTech Connect

    Blackwell, Matt; Rodger, Arthur; Kennedy, Tom

    2013-10-03

    When the California Academy of Sciences created the "Earthquake: Evidence of a Restless Planet" exhibit, they called on Lawrence Livermore to help combine seismic research with the latest data-driven visualization techniques. The outcome is a series of striking visualizations of earthquakes, tsunamis and tectonic plate evolution. Seismic-wave research is a core competency at Livermore. While most often associated with earthquakes, the research has many other applications of national interest, such as nuclear explosion monitoring, explosion forensics, energy exploration, and seismic acoustics. For the Academy effort, Livermore researchers simulated the San Andreas and Hayward fault events at high resolutions. Such calculations require significant computational resources. To simulate the 1906 earthquake, for instance, visualizing 125 seconds of ground motion required over 1 billion grid points, 10,000 time steps, and 7.5 hours of processor time on 2,048 cores of Livermore's Sierra machine.

  15. Learning by Doing, Creating a Museum Exhibit.

    ERIC Educational Resources Information Center

    Main, Sarah; Kallquist, Dierdre

    2000-01-01

    Describes an exhibit called Kid's Kitchen, built within a major exhibit called Biodiversity: Life Supporting Life, in order to discuss environmental prompts hidden within the kitchen designed to surprise students and get them thinking. (ASK)

  16. Science Education Through a Museum Exhibit

    ERIC Educational Resources Information Center

    Chaparian, Azad; And Others

    1973-01-01

    Describes the polywater exhibit at the Worcester Science Center in Massachusetts. Curiosity and interest are stimulated in young people by allowing them to handle the materials in the exhibit and by providing them with instructions for making polywater. (JR)

  17. 29 CFR 2200.70 - Exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... prohibits its convenient transportation and storage. A party may offer into evidence photographs, models or... separate file designated for rejected exhibits. (e) Return of physical exhibits. A party may on motion request the return of a physical exhibit within 30 days after expiration of the time for filing a...

  18. Periadolescent rats (P41-50) exhibit increased susceptibility to D-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21-30 or P31-40) or adult rats (P51-60).

    PubMed

    Vorhees, Charles V; Reed, Tracy M; Morford, LaRonda L; Fukumura, Masao; Wood, Sandra L; Brown, Carrie A; Skelton, Matthew R; McCrea, Anne E; Rock, Stephanie L; Williams, Michael T

    2005-01-01

    We have previously shown that P11-20 treatment with d-methamphetamine (MA) induces impaired spatial navigation in the Morris water maze (MWM), whereas P1-10 treatment does not. Little is known about the long-term behavioral consequences of MA during juvenile, adolescent, and early adult brain development. In dose-response experiments, we tested successive 10-day intervals of exposure to MA in rats (P21-30, P31-40, P41-50, and P51-60; four doses per day). MA dosing prior to P21 produces little or no toxicity; however, we observed an increased toxicity with advancing age. Across-age comparisons revealed no MWM acquisition or Cincinnati water maze (CWM) effects after MA treatment on P21-30 (2.5-10 mg/kg/dose), P31-40 (1.25-7.5 mg/kg/dose), or P51-60 (1.25-5.0 mg/kg/dose); however, significantly impaired MWM acquisition was observed after P41-50 MA treatment at the highest dose (6.25 mg/kg/dose). Learning in the CWM was also impaired in this group. No effects were seen at 1.25, 2.5, or 5 mg/kg/dose following P41-50 MA treatment. MWM reversal learning trials after P41-50 treatment showed a trend towards longer latency in all MA dose groups, but no effect on double-reversal trials. Reversal and double-reversal also showed no effects at the other exposure ages. No differences in straight channel swimming or cued learning in the MWM were seen after MA treatment at any exposure age. P41-50 is the periadolescent stage of brain development in rodents. The effects observed at this age may suggest a previously unrecognized period of susceptibility for MA-induced cognitive deficits.

  19. 75 FR 4439 - Culturally Significant Objects Imported for Exhibition Determinations: “An Uneasy Communion: Jews...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ..., Christians, and the Altarpieces of Medieval Aragon'' SUMMARY: Notice is hereby given of the following... ``An Uneasy Communion: Jews, Christians, and the Altarpieces of Medieval Aragon,'' imported from...

  20. 77 FR 48582 - Culturally Significant Objects Imported for Exhibition Determinations: “Plants of Virtue and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965, Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998, Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000 (and, as appropriate, Delegation of Authority No. 257 of......

  1. 75 FR 1009 - Culturally Significant Objects Imported for Exhibition Determinations: “Habsburg Treasures”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-07

    ... at the Norton Museum of Art, West Palm Beach, Florida, from on or about January 16, 2010, until on or about April 11, 2010; the Columbia Museum of Art, Columbia, South Carolina, from on or about May 21..., Florida, from on or about October 7, 2010, until on or about December 30, 2010, and at possible...

  2. 78 FR 71022 - Culturally Significant Objects Imported for Exhibition Determinations: “Piero della Francesca...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No.......

  3. 78 FR 12134 - Culturally Significant Objects Imported for Exhibition Determinations: “Temple and Tomb...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... World, New York University, New York, NY, from on or about March 20, 2013, until on or about July 7... the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27,...

  4. ABSENCE OF SIGNIFICANT COOL DISKS IN YOUNG STELLAR OBJECTS EXHIBITING REPETITIVE OPTICAL OUTBURSTS

    SciTech Connect

    Liu, Hauyu Baobab; Hirano, Naomi; Takami, Michihiro; Dong, Ruobing; Galván-Madrid, Roberto; Rodríguez, Luis F.; Carrasco-González, Carlos; Vorobyov, Eduard I.; Kóspál, Ágnes; Dunham, Michael M.; Henning, Thomas; Hashimoto, Jun; Hasegawa, Yasuhiro

    2016-01-10

    We report Submillimeter Array 1.3 mm high angular resolution observations toward the four EXor-type outbursting young stellar objects VY Tau, V1118 Ori, V1143 Ori, and NY Ori. The data mostly show low dust masses M{sub dust} in the associated circumstellar disks. Among the sources, NY Ori possesses a relatively massive disk with M{sub dust} ∼ 9 × 10{sup −4}M{sub ⊙}. V1118 Ori has a marginal detection equivalent to M{sub dust} ∼ 6 × 10{sup −5}M{sub ⊙}. V1143 Ori has a non-detection also equivalent to M{sub dust} < 6 × 10{sup −5}M{sub ⊙}. For the nearest source, VY Tau, we get a surprising non-detection that provides a stringent upper limit M{sub dust} < 6 × 10{sup −6}M{sub ⊙}. We interpret our findings as suggesting that the gas and dust reservoirs that feed the short-duration, repetitive optical outbursts seen in some EXors may be limited to the small-scale, innermost region of their circumstellar disks. This hot dust may have escaped our detection limits. Follow-up, more sensitive millimeter observations are needed to improve our understanding of the triggering mechanisms of EXor-type outbursts.

  5. 78 FR 43960 - Culturally Significant Objects Imported for Exhibition Determinations: “Dante Ferretti: Design...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... Construction for Cinema'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... ``Dante Ferretti: Design and Construction for Cinema,'' imported from abroad for temporary...

  6. 77 FR 71472 - Culturally Significant Objects Imported for Exhibition Determinations: A Hellenistic “Herakles...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No.......

  7. 78 FR 77772 - Culturally Significant Objects Imported for Exhibition Determinations: “A Royal Passion: Queen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... Photography'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority... ``A Royal Passion: Queen Victoria and Photography,'' imported from abroad for temporary...

  8. 76 FR 6650 - Culturally Significant Objects Imported for Exhibition Determinations: “Birth of the Modern...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... Identity in Vienna 1900'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the... ``Birth of the Modern: Style and Identity in Vienna 1900,'' imported from abroad for temporary...

  9. 76 FR 44394 - Culturally Significant Objects Imported for Exhibition Determinations: “Pacific Standard Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... in L.A. Painting and Sculpture 1950-1970'' SUMMARY: Notice is hereby given of the following... ``Pacific Standard Time: Crosscurrents in L.A. Painting and Sculpture 1950-1970,'' imported from abroad...

  10. 77 FR 12352 - Culturally Significant Objects Imported for Exhibition Determinations: “Bellini, Titian and Lotto...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... Italian Paintings From the Accademia Carrara, Bergamo'' SUMMARY: Notice is hereby given of the following... ``Bellini, Titian and Lotto: North Italian Paintings from the Accademia Carrara, Bergamo'' imported...

  11. 76 FR 30228 - Culturally Significant Object Imported for Exhibition; Determinations: “Portrait of a Man”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No.......

  12. 75 FR 43225 - Culturally Significant Objects Imported for Exhibition Determinations: “Man, Myth, and Sensual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No.......

  13. 76 FR 77582 - Culturally Significant Objects Imported for Exhibition Determinations: “Beauty and Belief...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No.......

  14. Marigold flower-powder exhibits significant potential to inhibit lipid oxidation in rice bran tea.

    PubMed

    Wanyo, Pitchaporn; Kaewseejan, Niwat; Meeso, Naret; Siriamornpun, Sirithon

    2015-06-01

    We supplemented marigold flower-powder (MFP) in rice bran tea at different proportions as a source of natural antioxidant compounds. Changes of phenolic compounds, antioxidant activity, fatty acid composition and lipid oxidation in the rice bran tea with MFP after 30 days of storage were investigated, comparing results with the initial data. Adding MFP in rice bran tea resulted in an increased content and composition of phenolics and flavonoids along with enhanced antioxidant activities, which were increased in a dose-dependent manner. As a result, MFP supplementation of rice bran tea was able to retard the lipid oxidation as determined by the peroxide value (PV), due to the protection of essential fatty acids during 30 days of storage. The PVs were strongly negatively correlated (p < 0.01) with phenolic compounds, total phenolic content (TPC) and total flavonoid content (TFC), but were positively correlated with tocopherols and γ-oryzanol contents. We also found that the PV was positively correlated with the PUFA (poly unsaturated fatty acid) content but adverse results were found for SFA (saturated fatty acid) and MUFA (mono unsaturated fatty acid) contents. These findings suggest that MFP could be used as a natural antioxidant in foods for preventing lipid oxidation as well as extending the shelf-life of food products.

  15. 78 FR 59750 - Culturally Significant Objects Imported for Exhibition Determinations: “Isa Genzken: Retrospective”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE... Adviser, U.S. Department of State (telephone: 202-632-6467). The mailing address is U.S. Department of... Cultural Affairs, Department of State. BILLING CODE 4710-05-P...

  16. 78 FR 18664 - Culturally Significant Objects Imported for Exhibition Determinations: “Diaghilev and the Ballets...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ..., 1909-1929: When Art Danced With Music'' SUMMARY: Notice is hereby given of the following determinations... the Ballets Russes, 1909- 1929: When Art Danced with Music,'' imported from abroad for...

  17. 78 FR 79057 - Public Notice; Culturally Significant Objects Imported for Exhibition Determinations: “Treasures...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ...: Arts and Culture of the Joseon Dynasty, 1392-1910'' SUMMARY: Notice is hereby given of the following... ``Treasures from Korea: Arts and Culture of the Joseon Dynasty, 1392-1910,'' imported from abroad...

  18. Watershed dissolved organic carbon export patterns exhibit significant transport-limitations

    NASA Astrophysics Data System (ADS)

    Zarnetske, J. P.; Bouda, M.; Saiers, J. E.; Raymond, P. A.

    2013-12-01

    Dissolved organic carbon (DOC) is a master variable in aquatic ecosystems and drinking water quality. However, it is difficult to reveal how DOC travels from terrestrial environments to streams and is eventually exported from watersheds. Fundamentally, we need to reveal when and where DOC export is controlled by the sources of watershed DOC or the ability to hydrologically transport it. Therefore, we evaluate the importance of DOC source versus hydrologic transport limitations on watershed DOC export patterns across the United States. To do this, we analyzed empirical DOC flux (F_DOC) patterns across many watersheds (n= 655), which span a wide range of watershed sizes, flow regimes, climates, and biomes. They also represent 66% of the areal extent of the conterminous United States. We fit a power law model of F_DOC for each watershed, where F_DOC=aQ^b. This power-law model had a robust goodness of fit for the watersheds in this data set (mean NSE=0.88). We used the calibrated b value for each watershed to characterize DOC export as either transport-limited (b>1; concurrent increase in DOC concentration with flow), chemostatic (b=1; constant DOC concentration with increasing flow), or source-limited (b<1; decreasing DOC concentration with increasing flow). This synthesis of watersheds demonstrates that DOC export is limited by transport processes in a large majority (69%) of the watersheds in the data set. Further, we used an ensemble method to fit statistical models (i.e., boosted regression trees) that predict the transport- vs source-limitation behavior of watersheds. The observed limitation behavior is largely associated with two land cover variables (evergreen forest and developed land extent) and climatic variables (annual precipitation and temperature seasonality). This synthesis indicates that the coupling of terrestrial and aquatic systems in terms of DOC is predominantly controlled by hydrologic transport processes. Overall, these DOC export findings suggest that future modeling efforts of basin-scale DOC storage and flux patterns will be improved by incorporating models of hydrologic transport conditions.

  19. 75 FR 22172 - Culturally Significant Objects Imported for Exhibition Determinations: “Vatican Splendors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ... objects at the Missouri History Museum, Saint Louis, Missouri, from on or about May 15, 2010, until on or about September 12, 2010, the Senator John Heinz History Center, Pittsburgh, Pennsylvania, from on or about October 2, 2010, until on or about January 9, 2011, the Museum of Art, Nova...

  20. 78 FR 71021 - Culturally Significant Objects Imported for Exhibition Determinations: “Antonio Canova: The Seven...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ...Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No.......

  1. 78 FR 11264 - Culturally Significant Objects Imported for Exhibition Determinations: “The Cyrus Cylinder in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ..., 2013, until on or about August 4, 2013; The Asian Art Museum, San Francisco, CA, from on or about August 9, 2013, until on or about September 22, 2013; the Getty Villa, The J. Paul Getty Museum,...

  2. 76 FR 28499 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso and Braque: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: May 11, 2011. Ann...

  3. 77 FR 39319 - Culturally Significant Objects Imported for Exhibition Determinations: “Bodies and Shadows...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ....; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of...: 202- 632-6467). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  4. 77 FR 22630 - Culturally Significant Objects Imported for Exhibition Determinations: “The Printed Image in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of...: 202- 632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  5. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Chinese Bronzes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000, I hereby determine that the... (telephone: 202- 632-6469). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor...

  6. 75 FR 7536 - Culturally Significant Objects Imported for Exhibition Determinations: “The Aztec Pantheon and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: February...

  7. 77 FR 2603 - Culturally Significant Objects Imported for Exhibition Determinations: “Princes and Painters in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: January 11,...

  8. 78 FR 53816 - Culturally Significant Objects Imported for Exhibition Determinations: “Van Gogh Repetitions”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... ] seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236-3 of August... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: August 26, 2013....

  9. 77 FR 26814 - Culturally Significant Objects Imported for Exhibition Determinations: “Modern Landscapes”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000... State, SA-5, L/PD, Fifth Floor (Suite 5H03), and Washington, DC 20522-0505. Dated: May 2, 2012. J....

  10. 75 FR 57826 - Culturally Significant Objects Imported for Exhibition Determinations: “On Line: Drawing Through...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ....; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of.... Department of State (telephone: 202- 632-6469). The mailing address is U.S. Department of State, SA-5,...

  11. 76 FR 77299 - Culturally Significant Objects Imported for Exhibition Determinations: “Van Gogh. Up Close”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000.... Department of State (telephone: (202) 632-6473). The mailing address is U.S. Department of State, SA-5,...

  12. 77 FR 34455 - Culturally Significant Objects Imported for Exhibition Determinations: “Century of the Child...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ....; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of...- 632-6467). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  13. 78 FR 62355 - Culturally Significant Objects Imported for Exhibition Determinations: “Ileana Sonnabend...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-18

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of... (telephone: 202- 632-6469). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor...

  14. 77 FR 41473 - Culturally Significant Objects Imported for Exhibition Determinations: “Lion Attacking a Horse”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000.... Department of State (telephone: 202- 632-6473). The mailing address is U.S. Department of State, SA-5,...

  15. 76 FR 35068 - Culturally Significant Objects Imported for Exhibition Determinations; “Monet/Lichtenstein: Rouen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: June 8, 2011. Ann...

  16. 78 FR 33885 - Culturally Significant Object Imported for Exhibition Determinations: “Fauno Rosso”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    .... 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: May 21, 2013....

  17. 77 FR 51103 - Culturally Significant Objects Imported for Exhibition Determinations: “Ferdinand Hodler: View to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236-3 of... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: August 15, 2012. J....

  18. 75 FR 8424 - Culturally Significant Objects Imported for Exhibition Determinations: “Matisse: Radical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236 of... of State, SA- 5, L/PD, Fifth Floor, Washington, DC 20522-0505. ] Dated: February 18, 2010. Maura...

  19. 76 FR 14115 - Culturally Significant Objects Imported for Exhibition Determinations: “Cross References”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: March 10, 2011. Ann...

  20. 77 FR 56251 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso Black and White”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000..., SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: September 5, 2012. J....

  1. 78 FR 19062 - Culturally Significant Objects Imported for Exhibition Determinations: “Hans Richter: Encounters”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000 (and, as... mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC...

  2. 77 FR 38881 - Culturally Significant Objects Imported for Exhibition Determinations: “Regarding Warhol: Sixty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ....S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of...: 202- 632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  3. 77 FR 3320 - Culturally Significant Objects Imported for Exhibition Determinations: “Print/Out”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    .... 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: January 11, 2012..., Department of State. [FR Doc. 2012-1262 Filed 1-20-12; 8:45 am] BILLING CODE 4710-05-P...

  4. 77 FR 26353 - Culturally Significant Objects Imported for Exhibition Determinations: “Lygia Clark”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000... (telephone: (202) 632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor...

  5. 77 FR 28419 - Culturally Significant Objects Imported for Exhibition Determinations: “Gustav Klimt: The Magic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: May 8, 2012....

  6. 78 FR 56766 - Culturally Significant Objects Imported for Exhibition Determinations: “Antonio Berni: Juanito...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236-3 of.... Department of ] State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: September...

  7. 77 FR 41473 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 98: Slavs and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3.... Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: June 29, 2012....

  8. 77 FR 32711 - Culturally Significant Objects Imported for Exhibition Determinations: “Messerschmidt and Modernity”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236...- 632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  9. 76 FR 14115 - Culturally Significant Objects Imported for Exhibition Determinations: “Assorted Greek and Roman...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3... of Art, New York, NY, from on or about April 1, 2011, until on or about April 1, 2013, and at... mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC...

  10. 75 FR 80885 - Culturally Significant Objects Imported for Exhibition Determinations: “The Buddhist Heritage of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3... Society, New York, New York, from on or about March 1, 2011, until on or about May 30, 2011, and at... mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC...

  11. 76 FR 73759 - Culturally Significant Objects Imported for Exhibition Determinations: “In Wonderland: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    .... 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000 (and, as appropriate... mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC...

  12. 76 FR 52044 - Culturally Significant Objects Imported for Exhibition Determinations: “Modern Antiquity: Picasso...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    .... 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000 (and, as appropriate...: 202-632-6473). The mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite...

  13. 76 FR 16851 - Culturally Significant Objects Imported for Exhibition Determinations: “Seeing Gertrude Stein...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3.... Department of State (telephone: 202-632-6469). The mailing address is U.S. Department of State, SA-5,...

  14. 76 FR 73760 - Culturally Significant Objects Imported for Exhibition Determinations: “The Holocaust”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ....), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000... mailing address is U.S. Department of State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC...

  15. 76 FR 64423 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 96: Haris...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ..., et seq.), Delegation of Authority No. 234 of October 1, 1999, Delegation of Authority No. 236-3 of... State, SA-5, L/PD, Fifth Floor (Suite 5H03), Washington, DC 20522-0505. Dated: October 12, 2011. J....

  16. Space exhibitions: the science encounters the public

    NASA Astrophysics Data System (ADS)

    Coliolo, F.; Menendez, M.

    The widespread dissemination of science has always been one pillar of the development of human knowledge. There are several methods to structure interaction with the public: media, conferences, various written genres, and exhibitions. But: how to attract the public? How to arouse interest among future generation, insatiable for knowledge? In this paper we focus on space exhibitions, whose content combines mystery, discovery and science. The preparation of an exhibition is based on guidelines discussed between an interdisciplinary team and the exhibition project manager, the purpose of which is to find a coherent "strategy" to select information and to choose a concise, efficient, smart and original way to "visualize" the messages. Exhibition visitors are "privileged" because the interactivity is first emotive, then mental and cultural; the audience is universal. The goal of an exhibition is not to explain the content, but to stimulate the audience's curiosity in an attractive environment. We show some photos of ESA exhibitions, and try to understand if the visual impact is the first step towards a "multi-sensory" approach to communication. "A good exhibition can never be replaced by a book, a film or a lecture. A good exhibition creates a thirst for books, film, lectures. A good exhibition changes the visitors"(J. Wagensberg, Modern scientific museology")

  17. Young Adult Literature for Young Adult Males.

    ERIC Educational Resources Information Center

    Gill, Sam D.

    1999-01-01

    Argues that young adult literature can play a significant role in the emotional and mental health of an adolescent as well as help young males become more literate. Offers a 19-item annotated list of young adult novels with male protagonists, sorted by themes: nature and adventure stories, sports stories, genre stories, historical stories, and…

  18. Superconductive microstrip exhibiting negative differential resistivity

    DOEpatents

    Huebener, R.P.; Gallus, D.E.

    1975-10-28

    A device capable of exhibiting negative differential electrical resistivity over a range of values of current and voltage is formed by vapor- depositing a thin layer of a material capable of exhibiting superconductivity on an insulating substrate, establishing electrical connections at opposite ends of the deposited strip, and cooling the alloy into its superconducting range. The device will exhibit negative differential resistivity when biased in the current- induced resistive state.

  19. Virtual Exhibition and Fruition of Archaeological Finds

    NASA Astrophysics Data System (ADS)

    Manferdini, A. M.; Garagnani, S.

    2011-09-01

    During the last two decades, since digital technologies have become more sophisticated in acquiring real data and building faithful copies of them, their improvements have suggested interesting applications in the field of valorisation of Historical, Cultural and Artistic Heritage, with significant consequences in the share and widespread of knowledge. But although several technologies and methodologies for 3d digitization have recently been developed and improved, the lack of a standard procedure and the costs connected to their use still doesn't encourage the systematic digital acquisition of wide collections and heritage. The aim of this paper is to show the state of the art of a project whose aim is to provide a methodology and a procedure to create digital reproductions of artefacts for Institutions called to preserve, manage and enhance the fruition of archaeological finds inside museums or through digital exhibitions. Our project's aim is to find the most suitable procedure to digitally acquire archaeo logical artefacts that usually have small dimensions and have very complex and detailed surfaces. Within our methodology, particular attention has been paid to the use of widely shared and open-source visualization systems that enhance the involvement of the user by emphasizing three-dimensional characteristics of artefacts through virtual reality.

  20. Marine bacteria exhibit a bipolar distribution.

    PubMed

    Sul, Woo Jun; Oliver, Thomas A; Ducklow, Hugh W; Amaral-Zettler, Linda A; Sogin, Mitchell L

    2013-02-05

    The microbial cosmopolitan dispersion hypothesis often invoked to explain distribution patterns driven by high connectivity of oceanographic water masses and widespread dispersal ability has never been rigorously tested. By using a global marine bacterial dataset and iterative matrix randomization simulation, we show that marine bacteria exhibit a significantly greater dispersal limitation than predicted by our null model using the "everything is everywhere" tenet with no dispersal limitation scenario. Specifically, marine bacteria displayed bipolar distributions (i.e., species occurring exclusively at both poles and nowhere else) significantly less often than in the null model. Furthermore, we observed fewer taxa present in both hemispheres but more taxa present only in a single hemisphere than expected under the null model. Each of these trends diverged further from the null expectation as the compared habitats became more geographically distant but more environmentally similar. Our meta-analysis supported a latitudinal gradient in bacterial diversity with higher richness at lower latitudes, but decreased richness toward the poles. Bacteria in the tropics also demonstrated narrower latitudinal ranges at lower latitudes and relatively larger ranges in higher latitudes, conforming to the controversial macroecological pattern of the "Rapoport rule." Collectively, our findings suggest that bacteria follow biogeographic patterns more typical of macroscopic organisms, and that dispersal limitation, not just environmental selection, likely plays an important role. Distributions of microbes that deliver critical ecosystem services, particularly those in polar regions, may be vulnerable to the same impacts that environmental stressors, climate warming, and degradation in habitat quality are having on biodiversity in animal and plant species.

  1. Encountering Nanotechnology in an Interactive Exhibition

    ERIC Educational Resources Information Center

    Murriello, Sandra E.; Knobel, Marcelo

    2008-01-01

    This article offers findings from a learning sciences-informed evaluation of a nanoscience and nanotechnology exhibition called Nano-Aventura (NanoAdventure), based on four interactive-collaborative games and two narrated videos. This traveling exhibition was developed in Brazil by the Museu Exploratorio de Ciencias for children and teenagers…

  2. Learning4Life on the Exhibit Floor

    ERIC Educational Resources Information Center

    Sullivan, Margaret

    2009-01-01

    The exhibit floor is a wealth of knowledge. One can read, view, and listen to information presented in many formats. Somewhere on the exhibit floor there are experts on every topic, ready and waiting for one's questions. But like any research topic, frequently a structured search is required to find the best answers. This article discusses how to…

  3. Evaluation of Clientele Impact of Science Exhibits.

    ERIC Educational Resources Information Center

    Talisayon, Vivien M.

    1998-01-01

    Explores the use of an impact evaluation model across time and clientele groups that is used to evaluate exhibits from two science centers in Manila. Questionnaire and interview data indicate that students prefer exhibits that produce sound, light, and motion. (DDR)

  4. 49 CFR 250.2 - Required exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... statement, together with supporting evidence, that the probable value of the assets of the railroad in the... carrier's existing railroad. (5) As Exhibit 5, statement showing miles of line owned; miles operated... carried; and identification of the ten most important industries served. (6) As Exhibit 6, statement as...

  5. Science Fiction Exhibits as STEM Gateways

    NASA Astrophysics Data System (ADS)

    Robie, Samantha

    Women continue to hold less than a quarter of all STEM jobs in the United States, prompting many museums to develop programs and exhibits with the express goal of interesting young girls in scientific fields. At the same time, a number of recent museum exhibits have harnessed the popularity of pop culture and science fiction in order to interest general audiences in STEM subject matter, as well as using the exhibits as springboards to expand or shift mission goals and focus. Because science fiction appears to be successful at raising interest in STEM fields, it may be an effective way to garner the interest of young girls in STEM in particular. This research seeks to describe the ways in which museums are currently using science fiction exhibits to interest young girls in STEM fields and careers. Research focused on four institutions across the country hosting three separate exhibits, and included staff interviews and content analysis of exhibit descriptions, promotional materials, a summative evaluation and supplementary exhibit productions. In some ways, science fiction exhibits do serve young girls, primarily through the inclusion of female role models, staff awareness, and prototype testing to ensure interactives are attractive to girls as well as to boys. However, STEM appears to be underutilized, which may be partly due to a concern within the field that the outcome of targeting a specific gender could be construed as "stereotyping".

  6. Strategies for Determining Exhibit Effectiveness. Final Report.

    ERIC Educational Resources Information Center

    Shettel, Harris H.; And Others

    This project was designed to develop research strategies and hypotheses for evaluating the effectiveness of exhibits. An exhibit on the role of the Federal Government in science and technology was used as the subject matter. Two basic groups of viewers were used, casual viewers and paid experimental viewers. Both were tested on knowledge gained…

  7. 7 CFR Exhibit G to Subpart E of... - Exhibit G to Subpart E of Part 1980

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exhibit G to Subpart E of Part 1980 G Exhibit G to Subpart E of Part 1980 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING... Program Pt. 1980, Subpt. E, Exh. G Exhibit G to Subpart E of Part 1980 Note: The Exhibit is not...

  8. Exhibition of Stochastic Resonance in Vestibular Perception

    NASA Technical Reports Server (NTRS)

    Galvan-Garza, R. C.; Clark, T. K.; Merfeld, D. M.; Bloomberg, J. J.; Oman, C. M.; Mulavara, A. P.

    2016-01-01

    (OTO) with SVS up to 700 µA. A sinusoidal galvanic vestibular stimulation (GVS) perceptual threshold was also measured on each test day and used to normalize the SVS levels across subjects. In roll-tilt thresholds with SVS, the characteristic SR curve was qualitatively exhibited in 10 of 12 subjects, and the improvement in motion threshold was significant in 6 subjects, indicating that optimal SVS improved passive body motion perception in a way that is consistent with classical SR theory. A probabilistic comparison to numeric simulations further validated these experimental results. On the second test session, 4 out of the 10 SR exhibitors showed repeated improvement with SVS compared to the no SVS condition. Data collection is ongoing for the last two test sessions in which SCC and OTO only perceptual motion recognition thresholds are being measured with SVS. The final results of these test sessions will give insight into whether vestibular perceptual SR can occur when only one type of vestibular sensor is sensing motion or if it is more evident when sensory integration between the SCC and OTO is occurring during the motion. The overall purpose of this research is to further quantify the effects of SVS on various sensorimotor tasks and to gain a more fundamental understanding of how SVS causes SR in the vestibular system. In the context of human space flight, results from this research will help in understanding how SVS may be practically implemented in the future as a component of a comprehensive countermeasure plan for G-transition adaptation.

  9. Science, providence, and progress at the Great Exhibition.

    PubMed

    Cantor, Geoffrey

    2012-09-01

    The Great Exhibition of 1851 is generally interpreted as a thoroughly secular event that celebrated progress in science, technology, and industry. In contrast to this perception, however, the exhibition was viewed by many contemporaries as a religious event of considerable importance. Although some religious commentators were highly critical of the exhibition and condemned the display of artifacts in the Crystal Palace as giving succor to materialism, others incorporated science and technology into their religious frameworks. Drawing on sermons, tracts, and the religious periodical press, this essay pays close attention to the ways in which science and technology were endowed with providentialist significance and particularly examines the notion of human progress used by a number of Christian writers, especially Congregationalists, who set scientific and technological progress within a teleological religious perspective. This discussion sheds fresh light not only on the Great Exhibition itself but also on the deployment of natural theology in mid-nineteenth-century Britain.

  10. Waves in geomaterials exhibiting negative stiffness behaviour

    NASA Astrophysics Data System (ADS)

    Esin, Maxim; Dyskin, Arcady; Pasternak, Elena

    2016-04-01

    Negative stiffness denotes the type of material behaviour when the force applied to the body decreases the body's deformation increases. Some geomaterials, for instance, rocks, demonstrate behaviour of this type at certain loads: during the compression tests the loading curves exhibit descending branch (post-peak softening). One of the possible mechanisms of the negative stiffness appearance in geomaterials is rotation of non-spherical grains. It is important to emphasize that in this case the descending branch may be reversible given that the testing machine is stiff enough (in general case it means an importance of boundary conditions). Existence of geomaterials with a negative modulus associated with rotations may have significant importance. In particular, important is understanding of the wave propagation in such materials. We study the stability of geomaterials with negative stiffness inclusions and wave propagation in it using two approaches: Cosserat continuum and discrete mass-spring models. In both cases we consider the rotational degrees of freedom in addition to the conventional translational ones. We show that despite non positiveness of the energy the materials with negative stiffness elements can be stable if certain conditions are met. In the case of Cosserat continuum the Cosserat shear modulus (the modulus relating the non-symmetrical part of shear stress and internal rotations) is allowed to assume negative values as long as its value does not exceed the value of the standard (positive) shear modulus. In the case of discrete mass-spring systems (with translational and rotational springs) the concentration of negative stiffness springs and the absolute values of negative spring stiffness are limited. The critical concentration when the system loses stability and the amplitude of the oscillations tends to infinity is equal to 1/2 and 3/5 for two- and three-dimensional cases respectively.

  11. 43 CFR 4.824 - Exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Procedural Rules Applicable to Practice and Procedure for Hearings, Decisions, and Administrative Review... Interior-Effectuation of Title VI of the Civil Rights Act of 1964 Procedures § 4.824 Exhibits....

  12. 18 CFR 32.2 - Required exhibits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of operating such facilities. Exhibit B. A general or key map on a scale not greater than 20 miles to... facilities used for the generation and transmission of electric energy, indicating on said map the...

  13. The Making of a Museum Exhibition.

    ERIC Educational Resources Information Center

    Bleecker, Samuel E.

    1979-01-01

    Discusses the preparation of the Reptile and Amphibian exhibition at the American Museum of Natural History. Various steps involved in developing the ten showcases in a six-year period are presented. (SA)

  14. 18 CFR 153.8 - Required exhibits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Exhibit D. If the proposal is for a pipeline interconnection to import or export natural gas, a copy of... authority, that will issue each required authorization; the date each request for authorization...

  15. When Do Children Exhibit a "Yes" Bias?

    ERIC Educational Resources Information Center

    Okanda, Mako; Itakura, Shoji

    2010-01-01

    This study investigated whether one hundred and thirty-five 3- to 6-year-old children exhibit a yes bias to various yes-no questions and whether their knowledge status affects the production of a yes bias. Three-year-olds exhibited a yes bias to all yes-no questions such as "preference-object" and "knowledge-object" questions pertaining to…

  16. Reaching the Public through Traveling Exhibitions

    NASA Astrophysics Data System (ADS)

    Dusenbery, P. B.; Harold, J. B.; Morrow, C. A.

    2004-11-01

    The Space Science Institute (SSI) of Boulder, Colorado has recently developed two museum exhibits called Alien Earths and MarsQuest. It has just started to develop another exhibit called Giant Planets. These exhibitions provide research scientists the opportunity to engage in a number of activities that are vital to the success of these major outreach programs. Alien Earths was developed in partnership with various research missions. The focus of the presentation will be on MarsQuest and Giant Planets. MarsQuest is a 5000 square-foot, \\$3M, traveling exhibition that is now touring the country. The exhibit's second 3-year tour will enable millions of Americans to share in the excitement of the scientific exploration of Mars and learn more about their own planet in the process. The associated planetarium show and education program will also be described, with particular emphasis on workshops to orient museum staff (e.g. museum educators and docents) and workshops for master educators near host museums and science centers. The workshops make innovative connections between the exhibition's interactive experiences and lesson plans aligned with the National Science Education Standards. These exhibit programs are good models for actively involving scientists and their discoveries to help improve informal science education in the museum community and for forging a stronger connection between formal and informal education. The presentation will also discuss how Giant Planets, a proposed 3500 square-foot traveling exhibition on the mysteries and discoveries of the outer planets, will be able to take advantage of the connections and resources that have been developed by the MarsQuest project.

  17. An Astrobiology Microbes Exhibit and Education Module

    NASA Technical Reports Server (NTRS)

    Lindstrom, Marilyn M.; Allen, Jaclyn S.; Stocco, Karen; Tobola, Kay; Olendzenski, Lorraine

    2001-01-01

    Telling the story of NASA-sponsored scientific research to the public in exhibits is best done by partnerships of scientists and museum professionals. Likewise, preparing classroom activities and training teachers to use them should be done by teams of teachers and scientists. Here we describe how we used such partnerships to develop a new astrobiology augmentation to the Microbes! traveling exhibit and a companion education module. "Additional information is contained in the original extended abstract."

  18. One exhibition, many goals. Combining scientific research and risk communication

    NASA Astrophysics Data System (ADS)

    Charrière, Marie; Bogaard, Thom; Junier, Sandra; Malet, Jean-Philippe; Mostert, Erik

    2015-04-01

    How effective is visual communication to increase awareness of natural hazards and risks? To answer this research question, we developed a research design that was at the same time an experimental setting and an actual communication effort. Throughout the full length of the 2-years project held in the Ubaye valley (southeastern France), we collaborated with local and regional stakeholders (politicians and technicians). During a consultation phase, the communication context was determined, the audience of the project was defined and finally the testing activity-communication effort was determined. We were offered the opportunity to design an exhibition for the local public library. In a consultation phase that corresponded to the design of the exhibition, the stakeholders contributed to its content as well as helping with the funding of the exhibition. Finally, during the experimentation phase, the stakeholders participated in advertising the activity, gathering of participants and designing the scientific survey. In order to assess the effects of the exhibition on risk awareness, several groups of children, teenagers and adults were submitted to a research design, consisting of 1) a pre-test, 2) the visit of the exhibition and 3) a post-test similar to the pre-test. In addition, the children answered a second post-test 3 months after the visit. Close ended questions addressed the awareness indicators mentioned in the literature, i.e. worry level, previous experiences with natural hazards events, exposure to awareness raising, ability to mitigate/respond/prepare, attitude to risk, and demographics. In addition, the post-test included several satisfaction questions concerning the visual tools displayed in the exhibition. A statistical analysis of the changes between the pre- and post- tests (paired t-test, Wilcoxon signed-rank test and bootstrapping) allowed to verify whether the exhibition had an impact on risk awareness or not. In order to deduce which variable

  19. Using Comparative Planetology in Exhibit Development

    NASA Astrophysics Data System (ADS)

    Dusenbery, P. B.; Harold, J. B.; Morrow, C. A.

    2004-12-01

    It is critically important for the public to better understand the scientific process. Museum exhibitions are an important part of informal science education that can effectively reach public audiences as well as school groups. They provide an important gateway for the public to learn about compelling scientific endeavors. The Space Science Institute (SSI) is a national leader in producing traveling science exhibitions and their associated educational programming (i.e. interactive websites, educator workshops, public talks, instructional materials). The focus of this presentation will be on three of its exhibit projects: MarsQuest (currently on tour), Alien Earths (in fabrication), and Giant Planets (in development). MarsQuest is enabling millions of Americans to share in the excitement of the scientific exploration of Mars and to learn more about their own planet in the process. Alien Earths will bring origins-related research and discoveries to students and the American public. It has four interrelated exhibit areas: Our Place in Space, Star Birth, PlanetQuest, and Search for Life. Exhibit visitors will explore the awesome events surrounding the birth of stars and planets; they will join scientists in the hunt for planets outside our solar system including those that may be in "habitable zones" around other stars; and finally they will be able to learn about how scientists are looking for signs of life beyond Earth. Giant Planets: Exploring the Outer Solar System will take advantage of the excitement generated by the Cassini mission and bring planetary and origins research and discoveries to students and the public. It will be organized around four thematic areas: Our Solar System; Colossal Worlds; Moons, Rings, and Fields; and Make Space for Kids. Giant Planets will open in 2007. This talk will focus on the importance of making Earth comparisons in the conceptual design of each exhibit and will show several examples of how these comparisons were manifested in

  20. Thiamine status in adult salmonines in the Great Lakes

    USGS Publications Warehouse

    Brown, S.B.; Honeyfield, D.C.; Hnath, J.G.; Wolgamood, M.; Marcquenski, S.V.; Fitzsimons, J.D.; Tillitt, D.E.

    2005-01-01

    In 1996 and again in 1999, hatchery personnel noted that some Lake Michigan coho salmon Oncorhynchus kisutch from fall spawning runs on the Platte River weir exhibited abnormal wiggling behavior that was similar to the behavior exhibited by thiamine-deficient Atlantic salmon Salmo salar, from the Baltic Sea. Samples of eggs or gonads, muscle, and liver from salmon and lake trout Salvelinus namaycush exhibiting abnormal behaviors were collected to determine the extent to which the behaviors were related to a thiamine deficiency. We compared these values with those found in normally behaving fish that produced offspring with high embryonic survival. In all adult fish exhibiting abnormal behavior, tissue residues of thiamine were among the lowest observed in the Great Lakes. Where embryonic survival was assessed, abnormal adult behavior was also associated with very high levels of offspring mortality due to early mortality syndrome. While the overall ecological significance remains to be determined, it appears that adult fish also exhibit neurological dysfunction and mortality associated with thiamine deficiency.