Science.gov

Sample records for adv atmos sci

  1. Advanced Multimission Operations System (ATMO)

    NASA Technical Reports Server (NTRS)

    Mandrake, Lucas; Thompson, David R.

    2013-01-01

    The HiiHat toolbox developed for CAT/ENVI provides principal investigators direct, immediate, flexible, and seamless interaction with their instruments and data from any location. Offering segmentation and neutral region division, it facilitates the discovery of key endmembers and regions of interest larger than a single pixel. Crucial to the analysis of hyperspectral data from Mars or Earth is the removal of unwanted atmospheric signatures. For Mars and the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM), residual atmospheric CO2 absorption is both directly problematic and indicative of processing errors with implications to the scientific utility of any particular image region. Estimating this residual error becomes key both in selecting regions of low distortion, and also to select mitigating methods, such as neutral region division. This innovation, the ATMO estimator, provides a simple, 0-1 normalized scalar that estimates this distortion (see figure). The metric is defined as the coefficient of determination of a quadratic fit in the region of distorting atmospheric absorption (approx 2 micron). This mimics the behavior of existing CRISM team mineralogical indices to estimate the presence of known, interesting mineral signatures. This facilitates the ATMO metric's assimilation into existing planetary geology workflows.

  2. 75 FR 49233 - Amendments to Form ADV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... From the Federal Register Online via the Government Publishing Office ] Part III Securities and... / Vol. 75 , No. 155 / Thursday, August 12, 2010 / Rules and Regulations#0;#0; ] SECURITIES AND EXCHANGE COMMISSION 17 CFR Parts 275 and 279 RIN 3235-AI17 Amendments to Form ADV AGENCY: Securities and...

  3. Atmospheric Trace Molecule Spectroscopy (ATMOS) Experiment Version 3 data retrievals.

    PubMed

    Irion, Fredrick W; Gunson, Michael R; Toon, Geoff C; Chang, Albert Y; Eldering, Annmarie; Mahieu, Emmanuel; Manney, Gloria L; Michelsen, Hope A; Moyer, Elizabeth J; Newchurch, Michael J; Osterman, Gregory B; Rinsland, Curtis P; Salawitch, Ross J; Sen, Bhaswar; Yung, Yuk L; Zander, Rodolphe

    2002-11-20

    Version 3 of the Atmospheric Trace Molecule Spectroscopy (ATMOS) experiment data set for some 30 trace and minor gas profiles is available. From the IR solar-absorption spectra measured during four Space Shuttle missions (in 1985, 1992, 1993, and 1994), profiles from more than 350 occultations were retrieved from the upper troposphere to the lower mesosphere. Previous results were unreliable for tropospheric retrievals, but with a new global-fitting algorithm profiles are reliably returned down to altitudes as low as 6.5 km (clouds permitting) and include notably improved retrievals of H2O, CO, and other species. Results for stratospheric water are more consistent across the ATMOS spectral filters and do not indicate a net consumption of H2 in the upper stratosphere. A new sulfuric-acid aerosol product is described. An overview of ATMOS Version 3 processing is presented with a discussion of estimated uncertainties. Differences between these Version 3 and previously reported Version 2 ATMOS results are discussed. Retrievals are available at http://atmos.jpl.nasa.gov/atmos.

  4. Science support for the atmospheric trace molecule spectroscopy (ATMOS) experiment

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.

    1982-01-01

    The experiment is a satellite solar occultation interferometer spectrometer experiment under development for flight on Spacelab 3. Launch is expected in March 1985. ATMOS will provide high spectral resolution (0.02/cm) and high spatial resolution (2 km from Shuttle altitude) data over the spectral range from 2 micrometers to 16 micrometers. This region of the spectrum is rich in absorption features of major and minor trace gases which are critical to the understanding of the chemistry and physics of the Earth's upper atmosphere. The broad objectives of the ATMOS experiment are to: identify and measure, on a global scale, the volume mixing ratios of known and newly discovered molecular species; determine vertical profiles for these species; and provide spectral data on the atmosphere for use in optimizing the design of future instruments to monitor specific gases.

  5. ATMOS: Long term atmospheric measurements for mission to planet Earth

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A long-term, space-based measurement program, together with continued balloon and aircraft-borne investigations, is essential to monitor the predicted effects in the atmosphere, to determine to what extent the concentration measurements agree with current models of stratospheric chemistry, and to determine the condition of the ozone layer. The Atmospheric Trace Molecule Spectroscopy (ATMOS) Experiment is currently making comprehensive, global measurements of Earth's atmosphere as part of the Atmospheric Laboratory for Applications and Science (ATLAS) program on the Space Shuttle. Part of NASA's Mission to Planet Earth, ATLAS is a continuing series of missions to study Earth and the Sun and provide a more fundamental understanding of the solar influences on Earth's atmosphere. The ATMOS program, instruments, and science results are presented.

  6. Heavy Ozone Enrichments from ATMOS Infrared Solar Spectra

    NASA Technical Reports Server (NTRS)

    Irion, F. W.; Gunson, M. R.; Rinsland, C. P.; Yung, Y. L.; Abrams, M. C.; Chang, A. Y.; Goldman, A.

    1996-01-01

    Vertical enrichment profiles of stratospheric O-16O-16O-18 and O-16O-18O-16 (hereafter referred to as (668)O3 and (686)O3 respectively) have been derived from space-based solar occultation spectra recorded at 0.01 cm(exp-1) resolution by the ATMOS (Atmospheric Trace MOlecule Spectroscopy) Fourier transform infrared (FTIR) spectrometer. The observations, made during the Spacelab 3 and ATLAS-1, -2, and -3 shuttle missions, cover polar, mid-latitude and tropical regions between 26 to 2.6 mb inclusive (approximately 25 to 41 km). Average enrichments, weighted by molecular (48)O3 density, of (15 +/- 6)% were found for (668)O3 and (10 +/- 7)% for (686)O3. Defining the mixing ratio of (50)O3 as the sum of those for (668)O3 and (686)O3, an enrichment of (13 plus or minus 5)% was found for (50)O3 (1 sigma standard deviation). No latitudinal or vertical gradients were found outside this standard deviation. From a series of ground-based measurements by the ATMOS instrument at Table Mountain, California (34.4 deg N), an average total column (668)O3 enrichment of (17 +/- 4)% (1 sigma standard deviation) was determined, with no significant seasonal variation discernable. Possible biases in the spectral intensities that affect the determination of absolute enrichments are discussed.

  7. Floc Growth and Changes in ADV Acoustic Backscatter Signal

    NASA Astrophysics Data System (ADS)

    Rouhnia, M.; Keyvani, A.; Strom, K.

    2013-12-01

    A series of experiments were conducted to examine the effect of mud floc growth on the acoustic back-scatter signal recorded by a Nortek Vector acoustic Doppler velocimeter (ADV). Several studies have shown that calibration equations can be developed to link the backscatter strength with average suspended sediment concentration (SSC) when the sediment particle size distribution remains constant. However, when mud is present, the process of flocculation can alter the suspended particle size distribution. Past studies have shown that it is still unclear as to the degree of dependence of the calibration equation on changes in floc size. Part of the ambiguity lies in the fact that flocs can be porous and rather loosely packed and therefore might not scatter to the same extent as a grain of sand. In addition, direct, detailed measurements of floc size have not accompanied experiments examining the dependence of ADV backscatter and suspended sediment concentration. In this research, a set of laboratory experiments is used to test how floc growth affects the backscatter strength. The laboratory data is examined in light of an analytic model that was developed based on scatter theory to account for changes in both SSC and the floc properties of size and density. For the experiments, a turbulent suspension was created in a tank with a rotating paddle. Fixed concentrations of a mixture of kaolinite and montmorillonite were added to the tank in a step-wise manner. For each step, the flocs were allowed to grow to their equilibrium size before breaking the flocs with high turbulent mixing, adding more sediment, and then returning the mixing rate to a range suitable for the re-growth of flocs. During each floc growth phase, data was simultaneously collected at the same elevation in the tank using a floc camera to capture the changes in floc size, a Nortek Vector ADV for the acoustic backscatter, and a Campbell Scientific OBS 3+ for optical backscatter. Physical samples of the

  8. 75 FR 31429 - Atmos Pipeline-Texas; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Atmos Pipeline--Texas; Notice of Baseline Filing May 27, 2010. Take notice that on May 27, 2010, Atmos Pipeline--Texas submitted a baseline filing of its Statement of...

  9. Stratospheric infrared continuum absorptions observed by the ATMOS instrument

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Zander, R.; Namkung, J. S.; Farmer, C. B.; Norton, R. H.

    1989-01-01

    A quantitative analysis of infrared continuum absorption features observed in ATMOS/Spacelab 3 (1985) spectra of the lower stratosphere is reported. Continuous absorption produced primarily by the collision-induced fundamental vibration-rotation band of O2 and to a lesser extent by the superposition of H2O far line wings has been observed in the 1400 to 1800/cm interval below tangent heights of about 25 km. Continuum optical depths measured in microwindows nearly free of atmospheric line absorption are 0.78 + or - 0.06 times those calculated with the O2 absorption coefficients of Timofeyev and Tonkov (1978). Transmittance measurements in microwindows between 2395 and 2535/cm have been used to study continuous absorption from the collision induced fundamental vibration-rotation band of N2 and the far wings of strong CO2 lines. The measured transmittances have been analyzed to derive best fit absorption coefficients for the N2 pressure-induced band at lower stratospheric temperatures (about 210 K).

  10. Remote sensing of the earth's atmosphere by infrared absorption spectroscopy - An update of the ATMOS program

    NASA Technical Reports Server (NTRS)

    Zander, R.; Gunson, M. R.; Farmer, C. B.

    1989-01-01

    The NASA's Atmospheric Trace Molecule Spectroscopy (ATMOS) experiment was designed to address the requirements of the remote sensing of atmospheric composition on a four-dimensional basis (latitude, longitude, altitude, and time), necessary for understanding and predicting the effect of changes on the chemical balance of the atmosphere. This paper describes the ATMOS program, overviews the ATMOS instrument and its performance, and presents the results obtained during its first flight as part of the Spacelab 3 Space Shuttle mission (April 29 through May 6, 1985). Also discussed are prospects for further missions.

  11. A Comparison of Measurements from ATMOS and Instruments Aboard the ER-2 Aircraft: Halogenated Gases

    NASA Technical Reports Server (NTRS)

    Chang, A. Y.; Salawitch, R. J.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Zander, R.; Rinsland, C. P.; Elkins, J. W.; Dutton, G. S.; Volk, C. M.; Webster, C. R.; May, R. D.; Fahey, D. W.; Gao, R.-S.; Loewenstein, M.

    1996-01-01

    We compare volume mixing ratio profiles of N2O, CFC-11, CFC-12, CCl4, SF6, and HCl in the mid-latitude lower stratosphere measured by the ATMOS Fourier transform spectrometer on the ATLAS-3 Space Shuttle Mission with in situ measurements acquired from the NASA ER-2 aircraft during Nov. 1994. Good agreement is found between ATMOS and in situ correlations of [CFC-11], [CFC-12], and [SF6] with [N2O]. ATMOS measurements of [CCl4] are 15% high compared to ER-2 data, but agree within the systematic uncertainties. ATMOS observations of [HCl] vs [N2O] are within approximately 10% of ER-2 data for [HCl] > 1 ppbv, but exceed in situ measurements by larger fractional amounts for smaller [HCl]. ATMOS measurements of [ClONO2] agree well with values inferred from in situ observations of [ClO], [NO], and [O3]. The sum of [HCl] and [ClONO2] observed by ATMOS, supplemented by a minor contribution from [ClO] estimated with a photochemical model, is consistent with the levels of inorganic chlorine inferred from in situ measurements of chlorine source gases.

  12. Automated CO2 extraction from air for clumped isotope analysis in the atmo- and biosphere

    NASA Astrophysics Data System (ADS)

    Hofmann, Magdalena; Ziegler, Martin; Pons, Thijs; Lourens, Lucas; Röckmann, Thomas

    2015-04-01

    The conventional stable isotope ratios 13C/12C and 18O/16O in atmospheric CO2 are a powerful tool for unraveling the global carbon cycle. In recent years, it has been suggested that the abundance of the very rare isotopologue 13C18O16O on m/z 47 might be a promising tracer to complement conventional stable isotope analysis of atmospheric CO2 [Affek and Eiler, 2006; Affek et al. 2007; Eiler and Schauble, 2004; Yeung et al., 2009]. Here we present an automated analytical system that is designed for clumped isotope analysis of atmo- and biospheric CO2. The carbon dioxide gas is quantitatively extracted from about 1.5L of air (ATP). The automated stainless steel extraction and purification line consists of three main components: (i) a drying unit (a magnesium perchlorate unit and a cryogenic water trap), (ii) two CO2 traps cooled with liquid nitrogen [Werner et al., 2001] and (iii) a GC column packed with Porapak Q that can be cooled with liquid nitrogen to -30°C during purification and heated up to 230°C in-between two extraction runs. After CO2 extraction and purification, the CO2 is automatically transferred to the mass spectrometer. Mass spectrometric analysis of the 13C18O16O abundance is carried out in dual inlet mode on a MAT 253 mass spectrometer. Each analysis generally consists of 80 change-over-cycles. Three additional Faraday cups were added to the mass spectrometer for simultaneous analysis of the mass-to-charge ratios 44, 45, 46, 47, 48 and 49. The reproducibility for δ13C, δ18O and Δ47 for repeated CO2 extractions from air is in the range of 0.11o (SD), 0.18o (SD) and 0.02 (SD)o respectively. This automated CO2 extraction and purification system will be used to analyse the clumped isotopic signature in atmospheric CO2 (tall tower, Cabauw, Netherlands) and to study the clumped isotopic fractionation during photosynthesis (leaf chamber experiments) and soil respiration. References Affek, H. P., Xu, X. & Eiler, J. M., Geochim. Cosmochim. Acta 71, 5033

  13. Research Gaps and Technology Needs in Development of PHM for Passive AdvSMR Components

    SciTech Connect

    Meyer, Ryan M.; Ramuhalli, Pradeep; Coble, Jamie B.; Hirt, Evelyn H.; Mitchell, Mark R.; Wootan, David W.; Berglin, Eric J.; Bond, Leonard J.; Henager, Charles H.

    2014-01-01

    Advanced small modular reactors (AdvSMRs), which are based on modularization of advanced reactor concepts, may provide a longer-term alternative to traditional light-water reactors and near term small modular reactors (SMRs), which are based on integral pressurized water reactor (iPWR) concepts. SMRs are challenged economically due to losses in economy of scale, thus, there is increased motivation to reduce the controllable operations and maintenance (O&M) costs through automation technologies including prognostics health management (PHM) systems. In this regard, PHM systems have the potential to play a vital role in supporting the deployment of AdvSMRs and face several unique challenges with respect to implementation for passive AdvSMR components. This paper presents a summary of a research gaps and technical needs assessment performed for implementation of PHM for passive AdvSMR components. state-of-the-art in PHM.

  14. Research gaps and technology needs in development of PHM for passive AdvSMR components

    SciTech Connect

    Meyer, Ryan M.; Ramuhalli, Pradeep; Hirt, Evelyn H.; Mitchell, Mark R.; Wootan, David W.; Berglin, Eric J.; Henagar, Chuck H. Jr.; Coble, Jamie B.; Bond, Leonard J.

    2014-02-18

    Advanced small modular reactors (AdvSMRs), which are based on modularization of advanced reactor concepts, may provide a longer-term alternative to traditional light-water reactors and near-term small modular reactors (SMRs), which are based on integral pressurized water reactor (iPWR) concepts. SMRs are challenged economically because of losses in economy of scale; thus, there is increased motivation to reduce the controllable operations and maintenance costs through automation technologies including prognostics health management (PHM) systems. In this regard, PHM systems have the potential to play a vital role in supporting the deployment of AdvSMRs and face several unique challenges with respect to implementation for passive AdvSMR components. This paper presents a summary of a research gaps and technical needs assessment performed for implementation of PHM for passive AdvSMR components.

  15. The Atmospheric Trace Molecule Spectroscopy (ATMOS) Experiment: Deployment on the ATLAS Space Shuttle Missions

    NASA Technical Reports Server (NTRS)

    Gunson, M. R.; Abbas, M. M.; Abrams, M. C.; Allen, M.; Brown, L. R.; Brown, T. L.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Lowes, L. L..; Mahieu, E.; Manney, G. L.; Michelsen, H. A.; Newchurch, M. J.; Rinsland, C. P.; Salawitch, R. J.; Stiller, G. P.; Toon, G. C.; Yung, Y. L.; Zander, R.

    1996-01-01

    The ATMOS Fourier transform spectrometer was flown for a fourth time on the Space Shuttle as part of the ATLAS-3 instrument payload in November 1994. More than 190 sunrise and sunset occultation events provided measurements of more than 30 atmospheric trace gases at latitudes 3 - 49 deg N and 65 - 72 deg S, including observations both inside and outside the Antarctic polar vortex. The instrument configuration, data retrieval methodology, and mission background are described to place in context analyses of ATMOS data presented in this issue.

  16. Profiles of Stratospheric Chlorine Nitrate from ATMOS/ATLAS 1 Infrared Solar Occultation Spectra

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Abrams, M. C.; Zander, R.; Mahieu, E.; Goldman, A.; Ko, M. K. W.; Rodriguez, J. M.; Sze, N. D.

    1994-01-01

    Stratospheric volume mixing ration profiles of chlorine nitrate have been retrieved from 0.01-cm(sub -1) resolution infrared solar occutation spectra recorded at latitudes between 14 degrees N and 54 degrees S by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS 1 shuttle mission (March 24 to April 2, 1992).

  17. 78 FR 39720 - Atmos Pipeline and Storage, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... Commission an application under section 7(b) of the Natural Gas Act (NGA) to abandon: (1) Its certificate of... gas storage caverns, 7.4 miles of interconnecting pipeline and other appurtenant facilities located in... Energy Regulatory Commission Atmos Pipeline and Storage, LLC; Notice of Application Take notice that...

  18. Local-Level Prognostics Health Management Systems Framework for Passive AdvSMR Components. Interim Report

    SciTech Connect

    Ramuhalli, Pradeep; Roy, Surajit; Hirt, Evelyn H.; Pardini, Allan F.; Jones, Anthony M.; Deibler, John E.

    2014-09-12

    This report describes research results to date in support of the integration and demonstration of diagnostics technologies for prototypical AdvSMR passive components (to establish condition indices for monitoring) with model-based prognostics methods. The focus of the PHM methodology and algorithm development in this study is at the localized scale. Multiple localized measurements of material condition (using advanced nondestructive measurement methods), along with available measurements of the stressor environment, enhance the performance of localized diagnostics and prognostics of passive AdvSMR components and systems.

  19. Preface: SciDAC 2009

    NASA Astrophysics Data System (ADS)

    Simon, Horst

    2009-07-01

    By almost any measure, the SciDAC community has come a long way since DOE launched the SciDAC program back in 2001. At the time, we were grappling with how to efficiently run applications on terascale systems (the November 2001 TOP500 list was led by DOE's ASCI White IBM system at Lawrence Livermore achieving 7.2 teraflop/s). And the results stemming from the first round of SciDAC projects were summed up in two-page reports. The scientific results were presented at annual meetings, which were by invitation only and typically were attended by about 75 researchers. Fast forward to 2009 and we now have SciDAC Review, a quarterly magazine showcasing the scientific computing contributions of SciDAC projects and related programs, all focused on presenting a comprehensive look at Scientific Discovery through Advanced Computing. That is also the motivation behind the annual SciDAC conference that in 2009 was held from June 14-18 in San Diego. The annual conference, which can also be described as a celebration of all things SciDAC, grew out those meetings organized in the early days of the program. In 2005, the meeting was held in San Francisco and attendance was opened up to all members of the SciDAC community. The schedule was also expanded to include a keynote address, plenary speakers and other features found in a conference format. This year marks the fifth such SciDAC conference, which now comprises four days of computational science presentations, multiple poster sessions and, since last year, an evening event showcasing simulations and modeling runs resulting from SciDAC projects. The fifth annual SciDAC conference was remarkable on several levels. The primary purpose, of course, is to showcase the research accomplishments resulting from SciDAC programs in particular and computational science in general. It is these accomplishments, represented in 38 papers and 52 posters, that comprise this set of conference proceedings. These proceedings can stand alone as

  20. 76 FR 255 - Amendments To Form ADV; Extension of Compliance Date

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... Commission is extending the compliance date generally for four months to provide certain investment advisers... of Investment Adviser Regulation, Division of Investment Management, U.S. Securities and Exchange... Commission adopted amendments to Part 2 of Form ADV , and related rules under the Investment Advisers Act...

  1. Preface: SciDAC 2007

    NASA Astrophysics Data System (ADS)

    Keyes, David E.

    2007-09-01

    It takes a village to perform a petascale computation—domain scientists, applied mathematicians, computer scientists, computer system vendors, program managers, and support staff—and the village was assembled during 24-28 June 2007 in Boston's Westin Copley Place for the third annual Scientific Discovery through Advanced Computing (SciDAC) 2007 Conference. Over 300 registered participants networked around 76 posters, focused on achievements and challenges in 36 plenary talks, and brainstormed in two panels. In addition, with an eye to spreading the vision for simulation at the petascale and to growing the workforce, 115 participants—mostly doctoral students and post-docs complementary to the conferees—were gathered on 29 June 2007 in classrooms of the Massachusetts Institute of Technology for a full day of tutorials on the use of SciDAC software. Eleven SciDAC-sponsored research groups presented their software at an introductory level, in both lecture and hands-on formats that included live runs on a local BlueGene/L. Computation has always been about garnering insight into the behavior of systems too complex to explore satisfactorily by theoretical means alone. Today, however, computation is about much more: scientists and decision makers expect quantitatively reliable predictions from simulations ranging in scale from that of the Earth's climate, down to quarks, and out to colliding black holes. Predictive simulation lies at the heart of policy choices in energy and environment affecting billions of lives and expenditures of trillions of dollars. It is also at the heart of scientific debates on the nature of matter and the origin of the universe. The petascale is barely adequate for such demands and we are barely established at the levels of resolution and throughput that this new scale of computation affords. However, no scientific agenda worldwide is pushing the petascale frontier on all its fronts as vigorously as SciDAC. The breadth of this conference

  2. Measurement of atmospheric composition by the ATMOS instrument from Table Mountain Observatory

    NASA Technical Reports Server (NTRS)

    Gunson, Michael R.; Irion, Fredrick W.

    1991-01-01

    Following its first flight on board the Space Shuttle 'Challenger' as part of the Spacelab 3 payload, the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument has been operated at the Jet Propulsion Laboratory's Table Mountain Observatory (TMO; 34.4 deg N, 117.7 deg W, 2.23 km altitude) in the San Gabriel Mountains of Southern California. With the delay in the resumption of regular Shuttle flights, ATMOS has acquired a large number of high-quality, high-resolution infrared solar absorption spectra, spanning a period between late-1985 and mid-1990. These spectra are being analyzed to derive the column abundances of several atmospheric species including O3, HCl, HF, and HNO3. Although limited in temporal coverage, the preliminary results for these gases are discussed here in the context of the requirement and contribution to be made by similar instruments in detecting long term changes in stratospheric composition.

  3. Increase of Stratospheric Carbon Tetrafluoride (CF4) Based on ATMOS Observations from Space

    NASA Technical Reports Server (NTRS)

    Zander, R.; Solomon, S.; Mahieu, E.; Goldman, A.; Rinsland, C. P.; Gunson, M. R.; Abrams, M. C.; Chang, A. Y.; Michelsen, H. A.; Newchurch, M. J.; Stiller, G. P.

    1996-01-01

    Stratospheric volume mixing ratio profiles of carbon tetrafluoride, CF4, obtained with the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument during the ATLAS (Atmospheric Laboratory for Applications and Science) -3 mission of 1994 are reported. Overall the profiles are nearly constant over the altitude range 20 to 50 km, indicative of the very long lifetime of CF4 in the atmosphere. In comparison to the stratospheric values of CF4 inferred from the ATMOS/Spacelab 3 mission of 1985, the 1994 concentrations are consistent with an exponential increase of (1.6 +/- 0.6)% yr(exp -1). This increase is discussed with regard to previous results and likely sources of CF4 at the ground. Further, it is shown that simultaneous measurements of N2O and CF4 provide a means of constraining the lower limit of the atmospheric lifetime of CF4 at least 2,300 years, two sigma.

  4. Trace Gas Transport in the Arctic Vortex Inferred from ATMOS ATLAS-2 Observations During April 1993

    NASA Technical Reports Server (NTRS)

    Abrams, M. C.; Manney, G. L.; Gunson, M. R.; Abbas, M. M.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Michelsen, H. A.; Newchurch, M. J.; Rinsland, C, P,; Salawitch, R. J.; Stiller, G. P.; Zander, R.

    1996-01-01

    Measurements of the long-lived tracers CH4, N2O, and HF from the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument during the Atmospheric Laboratory for Science and Applications-2 (ATLAS-2) Space Shuttle mission in April 1993 are used to infer average winter descent rates ranging from 0.8 km/month at 20 km to 3.2 km/month at 40 km in the Arctic polar vortex during the 1992-93 winter. Descent rates in the mid-stratosphere are similar to those deduced for the Antarctic vortex using ATMOS/ATLAS-3 measurements in November 1994, but the shorter time period of descent in the Arctic leads to smaller total distances of descent. Strong horizontal gradients observed along the vortex edge indicate that the Arctic vortex remains a significant barrier to transport at least until mid-April in the lower to middle stratosphere.

  5. Stratospheric sulfuric acid aerosols: composition and temperature discrimination with the ATMOS data set

    NASA Technical Reports Server (NTRS)

    Eldering, A.; Irion, F. W.; Mills, F. P.; Steele, H. M.; Kahn, B. H.; Gunson, M. R.

    2000-01-01

    The ATMOS Fourier transform spectrometer was flown for a fourth time on the Space Shuttle as part of the ATLAS-3 instrument payload in November 1994. More than 190 sunrise and sunset occultation events provided measurements of more than 30 atmospheric trace gases at latitudes 3-49(deg)N and 65-72(deg)S, including observations both inside and outside the Antarctic polar vortex.

  6. Preface: SciDAC 2006

    NASA Astrophysics Data System (ADS)

    Tang, William M., Dr.

    2006-01-01

    The second annual Scientific Discovery through Advanced Computing (SciDAC) Conference was held from June 25-29, 2006 at the new Hyatt Regency Hotel in Denver, Colorado. This conference showcased outstanding SciDAC-sponsored computational science results achieved during the past year across many scientific domains, with an emphasis on science at scale. Exciting computational science that has been accomplished outside of the SciDAC program both nationally and internationally was also featured to help foster communication between SciDAC computational scientists and those funded by other agencies. This was illustrated by many compelling examples of how domain scientists collaborated productively with applied mathematicians and computer scientists to effectively take advantage of terascale computers (capable of performing trillions of calculations per second) not only to accelerate progress in scientific discovery in a variety of fields but also to show great promise for being able to utilize the exciting petascale capabilities in the near future. The SciDAC program was originally conceived as an interdisciplinary computational science program based on the guiding principle that strong collaborative alliances between domain scientists, applied mathematicians, and computer scientists are vital to accelerated progress and associated discovery on the world's most challenging scientific problems. Associated verification and validation are essential in this successful program, which was funded by the US Department of Energy Office of Science (DOE OS) five years ago. As is made clear in many of the papers in these proceedings, SciDAC has fundamentally changed the way that computational science is now carried out in response to the exciting challenge of making the best use of the rapid progress in the emergence of more and more powerful computational platforms. In this regard, Dr. Raymond Orbach, Energy Undersecretary for Science at the DOE and Director of the OS has stated

  7. A first-order simulator to control dioxin emissions: NMCRC-ATMOS.

    PubMed

    Schwartz, Jeremy R; Mark, Shlomo; Wolfson, Adi

    2010-05-01

    Dioxins are highly toxic halogenated organic compounds formed as an unintentional by-product of many industrial processes involving chlorine and combustion. At the Negev Monte Carlo Research Center (NMCRC) and the Green Processes Center at the Shamoon College of Engineering (SCE), Israel, we have developed a code for the first-order estimation of dioxin emissions from waste incinerators and the subsequent atmospheric dispersion. The NMCRC-ATMOS (Atmospheric Evaluator) program will allow public planners and facility operators to estimate and predict the effect of current and potential waste incineration facilities on nearby population centres. This information can also be used by plant operators to decide whether to run the facilities at maximum capacity based on weather conditions. With the NMCRC-ATMOS tool, the user has the ability to easily establish location-based fallout from the average conditions (both facility and atmospheric) surrounding the waste incineration plant. This program currently focuses on dioxin emissions from waste incinerators, but can eventually be expanded to include other emission sources and atmospheric effects, as well as internet connectivity for real-time data acquisition. NMCRC-ATMOS is a Windows program that has been tested on Windows XP Service Pack 2 with the .NET Framework 2.0 installed.

  8. FAQs about Spinal Cord Injury (SCI)

    MedlinePlus

    ... spinal cord injury? Where is the nearest SCI Model System of Care? Emergency Medical Services Hospital (Acute) Care Rehabilitation More ... spinal cord injury? Where is the nearest SCI Model System of Care? Follow Us! Get Email Updates Questions & Comments Suggest ...

  9. Preface: SciDAC 2005

    NASA Astrophysics Data System (ADS)

    Mezzacappa, Anthony

    2005-01-01

    On 26-30 June 2005 at the Grand Hyatt on Union Square in San Francisco several hundred computational scientists from around the world came together for what can certainly be described as a celebration of computational science. Scientists from the SciDAC Program and scientists from other agencies and nations were joined by applied mathematicians and computer scientists to highlight the many successes in the past year where computation has led to scientific discovery in a variety of fields: lattice quantum chromodynamics, accelerator modeling, chemistry, biology, materials science, Earth and climate science, astrophysics, and combustion and fusion energy science. Also highlighted were the advances in numerical methods and computer science, and the multidisciplinary collaboration cutting across science, mathematics, and computer science that enabled these discoveries. The SciDAC Program was conceived and funded by the US Department of Energy Office of Science. It is the Office of Science's premier computational science program founded on what is arguably the perfect formula: the priority and focus is science and scientific discovery, with the understanding that the full arsenal of `enabling technologies' in applied mathematics and computer science must be brought to bear if we are to have any hope of attacking and ultimately solving today's computational Grand Challenge problems. The SciDAC Program has been in existence for four years, and many of the computational scientists funded by this program will tell you that the program has given them the hope of addressing their scientific problems in full realism for the very first time. Many of these scientists will also tell you that SciDAC has also fundamentally changed the way they do computational science. We begin this volume with one of DOE's great traditions, and core missions: energy research. As we will see, computation has been seminal to the critical advances that have been made in this arena. Of course, to

  10. ATMOS/ATLAS 3 Infrared Profile Measurements of Clouds in the Tropical and Subtropical Upper Troposphere

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Wang, P.-H.; Arduini, R. F.; Baum, B. A.; Minnis, P.; Goldman, A.; Abrams, M. C.; Zander, R.; Mahieu, E.; Salawitch, R. J.; Michelsen, H. A.; Irion, F. W.; Newchurch, M. J.

    1998-01-01

    Vertical profiles of infrared cirrus extinction have been derived from tropical and subtropical upper tropospheric solar occultation spectra. The measurements were recorded by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the Atmospheric Laboratory for Applications and Sciences (ATLAS) 3 shuttle flight in November 1994. The presence of large numbers of small ice crystals is inferred from the appearance of broad extinction features in the 8-12 micron region. These features were observed near the tropopause and at lower altitudes. Vertical profiles of the ice extinction (/km) in microwindows at 831, 957, and 1204/cm have been retrieved from the spectra and analyzed with a model for randomly oriented spheroidal ice crystals. An area-equivalent spherical radius of 6 microns is estimated from the smallest ice crystals observed in the 8-12 gm region. Direct penetration of clouds into the lower stratosphere is inferred from observations of cloud extinction extending from the upper troposphere to 50 mbar (20 km altitude). Cloud extinction between 3 and 5 microns shows very little wavelength dependence, at least for the cases observed by the ATMOS instrument in the tropics and subtropics during ATLAS 3.

  11. Atmos/Atlas 3 Infrared Profile Measurements of Clouds in the Tropical and Subtropical Upper Troposphere

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Wang, P.-H.; Arduini, R. F.; Baum, B. A.; Minnis, P.; Goldman, A.; Abrams, M. C.; Zander, R.; Mahieu, E.; Salawitch, R. J.; Michelsen, H. A.; Irions, F. W.; Newchurch, M. J.

    1998-01-01

    Vertical profiles of infrared cirrus extinction have been derived from tropical and subtropical upper tropospheric solar occultation spectra. The measurements were recorded by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the Atmospheric Laboratory for Applications and Sciences (ATLAS) 3 shuttle flight in November 1994. The presence of large numbers of small ice crystals is inferred from the appearance of broad extinction features in the 8-12 micron region. These features were observed near the tropopause and at lower altitudes. Vertical profiles of the ice extinction (/km) in microwindows at 831, 957, and 1204/cm have been retrieved from the spectra and analyzed with a model for randomly oriented spheroidal ice crystals. An area-equivalent spherical radius of 6 gm is estimated from the smallest ice crystals observed in the 8-12 micron region. Direct penetration of clouds into the lower stratosphere is inferred from observations of cloud extinction extending from the upper troposphere to 50 mbar (20 km altitude). Cloud extinction between 3 and 5 micron shows very little wavelength dependence, at least for the cases observed by the ATMOS instrument in the tropics and subtropics during ATLAS 3.

  12. Stratospheric NO and NO2 Abundances from ATMOS Solar-Occultation Measurements

    NASA Technical Reports Server (NTRS)

    Newchurch, M. J.; Allen, M.; Gunson, M. R.; Salawitch, R. J.; Collins, G. B.; Huston, K. H.; Abbas, M. M.; Abrams, M. C.; Chang, A. Y.; Fahey, D. W.; Gao, R. S.; Irion, F. W.; Lowenstein, M.; Manney, G. L.; Michelsen, H. A.; Podolske, J. R.; Rinsland, C. P.; Zander, R.

    1996-01-01

    Using results from a time-dependent photochemical model to calculate the diurnal variation of NO and NO2, we have corrected Atmospheric Trace MOlecule Spectroscopy (ATMOS) solar-occultation retrievals of the NO and NO2 abundances at 90' solar zenith angle. Neglecting to adjust for the rapid variation of these gases across the terminator results in potential errors in retrieved profiles of approximately 20% for NO2 and greater than 100% for NC at altitudes below 25 km. Sensitivity analysis indicates that knowledge of the local 03 and temperature profiles, rather than zonal mean or climatological conditions of these quantities, is required to obtain reliable retrievals of NO and NO2 in the lower stratosphere. Extremely inaccurate 03 or temperature values at 20 km can result in 50% errors in retrieved NO or NO2. Mixing ratios of NO in the mid-latitude, lower stratosphere measured by ATMOS during the November 1994 ATLAS-3 mission compare favorably with in situ ER-2 observations, providing strong corroboration of the reliability of the adjusted space-borne measurements.

  13. Preface: SciDAC 2008

    NASA Astrophysics Data System (ADS)

    Stevens, Rick

    2008-07-01

    The fourth annual Scientific Discovery through Advanced Computing (SciDAC) Conference was held June 13-18, 2008, in Seattle, Washington. The SciDAC conference series is the premier communitywide venue for presentation of results from the DOE Office of Science's interdisciplinary computational science program. Started in 2001 and renewed in 2006, the DOE SciDAC program is the country's - and arguably the world's - most significant interdisciplinary research program supporting the development of advanced scientific computing methods and their application to fundamental and applied areas of science. SciDAC supports computational science across many disciplines, including astrophysics, biology, chemistry, fusion sciences, and nuclear physics. Moreover, the program actively encourages the creation of long-term partnerships among scientists focused on challenging problems and computer scientists and applied mathematicians developing the technology and tools needed to address those problems. The SciDAC program has played an increasingly important role in scientific research by allowing scientists to create more accurate models of complex processes, simulate problems once thought to be impossible, and analyze the growing amount of data generated by experiments. To help further the research community's ability to tap into the capabilities of current and future supercomputers, Under Secretary for Science, Raymond Orbach, launched the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program in 2003. The INCITE program was conceived specifically to seek out computationally intensive, large-scale research projects with the potential to significantly advance key areas in science and engineering. The program encourages proposals from universities, other research institutions, and industry. During the first two years of the INCITE program, 10 percent of the resources at NERSC were allocated to INCITE awardees. However, demand for supercomputing resources

  14. A Comparison of Measurements from ATMOS and Instruments Aboard the ER-2 Aircraft: Tracers of Atmospheric Transport and Halogenated Gases

    NASA Technical Reports Server (NTRS)

    Chang, A. Y.; Salawitch, R. J.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Zander, R.; Rinsland, C. P.; Loewenstein, M.; Podolske, J. R.; Proffitt, M. H.; Margitan, J. J.; Fahey, D. W.; Gao, R.-S.; Kelly, K. K.; Elkins, J. W.; Webster, C. R.; May, R. D.; Chan, K. R.; Abbas, M. M.; Goldman, A.

    1996-01-01

    We compare volume mixing ratio profiles of N2O, O3, NO(y), H2O, CH4, and CO in the mid-latitude lower stratosphere measured by the ATMOS Fourier transform spectrometer on the ATLAS-3 Space Shuttle Mission with in situ measurements acquired from the NASA ER-2 aircraft during Nov 1994. ATMOS and ER-2 observations of (N2O) show good agreement, as do measured correlations of (O3), (NO(y)), (H2O), and (CH4) with (N2O). Thus a consistent measure of the hydrogen (H2O, CH4) content of the lower stratosphere is provided by the two platforms. The similarity of (NO(y)) determined by detection of individual species by ATMOS and the total (NOy) measurement on the ER-2 provides strong corroboration for the accuracy of both techniques. A 25% discrepancy in lower stratospheric (CO) observed by ATMOS and the ER-2 remains unexplained. Otherwise, the agreement for measurements of long-lived tracers demonstrates the ability to combine ATMOS data with in situ observations for quantifying atmospheric transport.

  15. A Comparison of Measurements from ATMOS and Instruments Aboard the ER-2 Aircraft: Tracers of Atmospheric Transport

    NASA Technical Reports Server (NTRS)

    Chang, A. Y.; Salawitch, R. J.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Zander, R.; Rinsland, C. P.; Loewenstein, M.; Podolske, J. R.; Proffitt, M. H.; Margitan, J. J.; Fahey, D. W.; Gao, R.-S.; Kelly, K. K.; Elkins, J. W.; Webster, C. R.; May, R. D.; Chan, K. R.; Abbas, M. M.; Goldman, A.

    1996-01-01

    We compare volume mixing ratio profiles of N2O, O3, NO(y) H2O, CH4, and CO in the mid-latitude lower stratosphere measured by the ATMOS Fourier transform spectrometer on the ATLAS-3 Space Shuttle Mission with in situ measurements acquired from the NASA ER-2 aircraft during Nov 1994. ATMOS and ER-2 observations of [N2O] show good agreement, as do measured correlations of [O3], [NO(y)], [H2O], and [CH4] with [N2O]. Thus a consistent measure of the hydrogen (H2O, CH4) content of the lower stratosphere is provided by the two platforms. The similarity of [NO(y)] determined by detection of individual species by ATMOS and the total [NO(y)] measurement on the ER-2 provides strong corroboration for the accuracy of both techniques. A 25% discrepancy in lower stratospheric [CO] observed by ATMOS and the ER-2 remains unexplained. Otherwise, the agreement for measurements of long-lived tracers demonstrates the ability to combine ATMOS data with in situ observations for quantifying atmospheric transport.

  16. SACR ADVance 3-D Cartesian Cloud Cover (SACR-ADV-3D3C) product

    DOE Data Explorer

    Meng Wang, Tami Toto, Eugene Clothiaux, Katia Lamer, Mariko Oue

    2017-03-08

    SACR-ADV-3D3C remaps the outputs of SACRCORR for cross-wind range-height indicator (CW-RHI) scans to a Cartesian grid and reports reflectivity CFAD and best estimate domain averaged cloud fraction. The final output is a single NetCDF file containing all aforementioned corrected radar moments remapped on a 3-D Cartesian grid, the SACR reflectivity CFAD, a profile of best estimate cloud fraction, a profile of maximum observable x-domain size (xmax), a profile time to horizontal distance estimate and a profile of minimum observable reflectivity (dBZmin).

  17. Complementary and alternative therapies and SCI nursing.

    PubMed

    Oliver, N R

    2001-01-01

    Increasing numbers of individuals are experimenting with different complementary and alternative techniques and practices in their quest to improve their health status or change symptom experiences. Consumer utilization patterns are described, activities to ensure the safety and efficacy of alternative practices are reviewed, and relationships to nursing interventions and nursing responsibilities are presented. The relationship between complementary/alternative therapies and spinal cord injury (SCI) nursing practice, education, and research are described, as well as strategies for integrating these therapies into SCI nursing. The potential roles for SCI nurses and benefits to individuals with SCI are unlimited.

  18. Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xenografted in mice.

    PubMed

    Dai, M; Liu, J; Chen, D-E; Rao, Y; Tang, Z-J; Ho, W-Z; Dong, C-Y

    2012-02-01

    Clinical efficacy of current therapies for hepatocellular carcinoma (HCC) treatment is limited. Indole-3-acetic acid (IAA) is non-toxic for mammalian cells. Oxidative decarboxylation of IAA by horseradish peroxidase (HRP) leads to toxic effects of IAA. The purpose of this study was to investigate the effects of a novel gene-targeted enzyme prodrug therapy with IAA on hepatoma growth in vitro and in vivo mouse hepatoma models. We generated a plasmid using adenovirus to express HRP isoenzyme C (HRPC) with the HCC marker, alpha-fetoprotein (AFP), as the promoter (pAdv-AFP-HRPC). Hepatocellular cells were infected with pAdv-AFP-HRPC and treated with IAA. Cell death was detected using MTT assay. Hepatoma xenografts were developed in mice by injection of mouse hepatoma cells. The size and weight of tumors and organs were evaluated. Cell death in tumors was assessed using hematoxylin and eosin-stained tissue sections. HRPC expression in tissues was detected using Reverse Transcriptase-Polymerase Chain Reaction. IAA stimulated death of hepatocellular cells infected with pAdv-AFP-HRPC, in a dose- and time-dependent manner, but not in control cells. Growth of hepatoma xenografts, including the size and weight, was inhibited in mice treated with pAdv-AFP-HRPC and IAA, compared with that in control group. pAdv-AFP-HRPC/IAA treatment induced cell death in hepatoma xenografts in mice. HRPC gene expressed only in hepatoma, but not in other normal organs of mice. pAdv-AFP-HRPC/IAA treatment did not cause any side effects on normal organs. These findings suggest that pAdv-AFP-HRPC/IAA enzyme/prodrug system may serve as a strategy for HCC therapy.

  19. The 1994 northern midlatitude budget of stratospheric chlorine derived from ATMOS/ATLAS-3 observations

    NASA Astrophysics Data System (ADS)

    Zander, R.; Mahieu, E.; Gunson, M. R.; Abrams, M. C.; Chang, A. Y.; Abbas, M.; Aellig, C.; Engel, A.; Goldman, A.; Irion, F. W.; Kämpfer, N.; Michelson, H. A.; Newchurch, M. J.; Rinsland, C. P.; Salawitch, R. J.; Stiller, G. P.; Toon, G. C.

    Volume mixing ratio (VMR) profiles of the chlorine-bearing gases HCl, ClONO2, CCl3F, CCl2F2, CHClF2, CCl4, and CH3Cl have been measured between 3 and 49° northern- and 65 to 72° southern latitudes with the Atmospheric Trace MOlecule Spectroscopy (ATMOS) instrument during the ATmospheric Laboratory for Applications and Science (ATLAS)-3 shuttle mission of 3 to 12 November 1994. A subset of these profiles obtained between 20 and 49°N at sunset, combined with ClO profiles measured by the Millimeter-wave Atmospheric Sounder (MAS) also from aboard ATLAS-3, measurements by balloon for HOCl, CH3CCl3 and C2Cl3F3, and model calculations for COClF indicates that the mean burden of chlorine, ClTOT, was equal to (3.53±0.10) ppbv (parts per billion by volume), 1-sigma, throughout the stratosphere at the time of the ATLAS 3 mission. This is some 37% larger than the mean 2.58 ppbv value measured by ATMOS within the same latitude zone during the Spacelab 3 flight of 29 April to 6 May 1985, consitent with an exponential growth rate of the chlorine loading in the stratosphere equal to 3.3%/yr or a linear increase of 0.10 ppbv/yr over the Spring-1985 to Fall-1994 time period. These findings are in agreement with both the burden and increase of the main anthropogenic Cl-bearing source gases at the surface during the 1980s, confirming that the stratospheric chlorine loading is primarily of anthropogenic origin.

  20. EVALUATION OF RANGE ESTIMATES FOR TOYOTA FCHV-ADV UNDER OPEN ROAD DRIVING CONDITIONS

    SciTech Connect

    Anton, D.; Wipke, K.; Sprik, S.

    2009-07-10

    The objective of this evaluation was to independently and objectively verify driving ranges of >400 miles announced by Toyota for its new advanced Fuel Cell Hybrid Vehicle (FCHV-adv) utilizing 70 MPa compressed hydrogen. To accomplish this, participants from both Savannah River National Laboratory (SRNL) and the National Renewable Energy Laboratory (NREL) witnessed and participated in a 2-vehicle evaluation with Toyota Motor Engineering & Manufacturing North America, Inc. (TEMA) over a typical open road route for over 11 hours in one day with all relevant data recorded. SRNL and TEMA first entered into discussions of verifying the range of the advanced Toyota Fuel Cell Hybrid Vehicle (FCHV-adv) in August 2008 resulting from reported 400+ mile range by Toyota. After extended negotiations, a CRADA agreement, SRNS CRADA No. CR-04-003, was signed on May 6, 2009. Subsequently, on June 30, 2009 SRNL and NREL participated in an all-day evaluation of the FCHV-adv with TEMA to determine the real-world driving range of this vehicle through on-road driving on an extended round-trip drive between Torrance and San Diego, California. SRNL and NREL observed the vehicles being refueled at Toyota's headquarters the day before the evaluation in Torrance, CA on June 29. At 8:00 AM on June 30, the vehicles departed Torrance north toward downtown Los Angeles, then west to the Pacific Coast Highway, and down to San Diego. After lunch the vehicles retraced their route back to Torrance. The traffic encountered was much heavier than anticipated, causing the vehicles to not return to Torrance until 9 PM. Each vehicle was driven by the same Toyota driver all day, with one SRNL/NREL observer in each vehicle the entire route. Data was logged by Toyota and analyzed by NREL. The maximum range of the FCHV-adv vehicles was calculated to be 431 miles under these driving conditions. This distance was calculated from the actual range of 331.5 miles during over 11 hours driving, plus 99.5 miles of

  1. [SciELO: method for electronic publishing].

    PubMed

    Laerte Packer, A; Rocha Biojone, M; Antonio, I; Mayumi Takemaka, R; Pedroso García, A; Costa da Silva, A; Toshiyuki Murasaki, R; Mylek, C; Carvalho Reisl, O; Rocha F Delbucio, H C

    2001-01-01

    It describes the SciELO Methodology Scientific Electronic Library Online for electronic publishing of scientific periodicals, examining issues such as the transition from traditional printed publication to electronic publishing, the scientific communication process, the principles which founded the methodology development, its application in the building of the SciELO site, its modules and components, the tools use for its construction etc. The article also discusses the potentialities and trends for the area in Brazil and Latin America, pointing out questions and proposals which should be investigated and solved by the methodology. It concludes that the SciELO Methodology is an efficient, flexible and wide solution for the scientific electronic publishing.

  2. Infrared spectroscopic measurements of halogenated source gases in the stratosphere with the ATMOS instrument

    NASA Technical Reports Server (NTRS)

    Zander, R.; Rinsland, C. P.; Farmer, C. B.; Norton, R. H.

    1987-01-01

    The volume mixing ratios of the six most important halogenated source species (CH3Cl, CF2Cl2, CFCl3, CHF2Cl, CCl4, and CF4) have been retrieved over the 10- to 30-km altitude range from the analysis of 0.01/cm resolution infrared solar occultation spectra recorded near 30 deg N and 47 deg S latitudes with the ATMOS (Atmospheric Trace Molecule Spectroscopy) instrument, operating from on board Spacelab 3 (April-May 1985). The results reported here, although in satisfactory agreement with recent in situ values obtained from air sampling techniques, are limited in accuracy by the limited absorption representative of most of the species and by uncertainties in the spectroscopic parameters currently available for these gases. They demonstrate, however, the power of the IR remote sensing approach for evaluating on a global scale the total chlorine budget of the atmosphere, and they provide an independent set of simultaneous data acquired for the important source and reservoir halogenated molecular species in the upper atmosphere.

  3. A Comparison of Ozone Measurements Made by the ATMOS, MAS, and SSBUV Instruments During ATLAS 1,2, and 3

    NASA Technical Reports Server (NTRS)

    Kriebel, D. L.; Bevilacqua, R. M.; Hilsenrath, E.; Gunson, M.; Hartmann, G. K.; Abrams, M.; Daehler, M.; Pauls, T. A.; Newchurch, M.; Aellig, C. P.; Bories, M. C.

    1996-01-01

    Ozone profile measurements were made by three instruments, ATMOS, MAS, and SSBUV, using distinctly different observing techniques, as part of the ATLAS Space Shuttle missions in March 1992, April 1993, and November 1994. ATMOS makes solar-occultation observations of infrared spectra using a Fourier transform interferometer. MAS uses a limb-scanning antenna to measure emission spectra at millimeter wavelengths. SSBUV is a nadir-viewing instrument measuring the transmission of scattered solar ultraviolet radiation modified by ozone absorption. A sample of zonal-mean mixing ratio profiles indicates that these three ATLAS instruments generally agree to within 10%, although a few potential biases have been noted. There are significant differences in the character of the agreement between ATLAS 1 and ATLAS 2 which will require further study.

  4. Plasma interferon-gamma, interleukin-10 and soluble markers of immune activation in infants with primary adenovirus (ADV) and respiratory syncytial virus (RSV) infection.

    PubMed

    Fernández, J Alonso; Tapia, Lorena; Palomino, M Angélica; Larrañaga, Carmen; Peña, Mónica; Jaramillo, Héctor

    2005-01-01

    Adenovirus (ADV) and respiratory syncytial virus (RSV) are etiological agents of acute respiratory tract infection in infants. Long-term prognosis of ADV infection includes severe lung damage, bronchiectasis and hyperlucent lung, while RSV infection is associated with development of recurrent wheezing and subsequent asthma. These differences may be related to differences in the primary immune responses elicited by these viruses. In this paper, we investigated the type of cytokine responses and the magnitude of immune activation in ADV and RSV infections in infants. We examined plasma concentrations of interferon-gamma (IFN-gamma), interleukin-10 (IL-10), soluble interleukin-2 receptor (sCD25) and soluble tumor necrosis factor receptor II (sTNFR-II) in previously healthy infants during the acute phase of primary ADV infection (n = 21) and RSV infection (n = 68), and in uninfected controls (n = 44). In ADV-infected infants, IFN-gamma plasma levels were significantly higher than those observed in RSV cases and the control group (p < 0.05). RSV cases did not show any differences in IFN-gamma plasma levels compared to the other groups. sCD25 levels were significantly higher in ADV- and RSV-infected infants than in controls (p < 0.0001), and higher in ADV than in RSV cases (p < 0.05). sTNFR-II levels were significantly higher in RSV- and ADV-infected infants than in controls (p < 0.0001, p < 0.05, respectively), and higher in RSV than in ADV infection (p < 0.05). No significant differences were observed in IL-10 plasma concentrations between the three groups. These results indicate that ADV and RSV infections in infants differ significantly with regard to the magnitude of production of interferon-gamma and soluble immune activation markers sCD25 and sTNFR-II. These immunological differences may be involved in the different clinical outcomes associated with these viral infections.

  5. Astronomy Popularization via Sci-fi Movies

    NASA Astrophysics Data System (ADS)

    Li, Qingkang

    2015-08-01

    It is astronomers’ duty to let more and more young people know a bit astronomy and be interested in astronomy and appreciate the beauty and great achievements in astronomy. One of the most effective methods to popularize astronomy to young people nowadays might be via enjoying some brilliant sci-fi movies related to astronomy with some guidance from astronomers. Firstly, we will introduce the basic information of our selective course “Appreciation of Sci-fi Movies in Astronomy” for the non-major astronomy students in our University, which is surely unique in China, then we will show its effect on astronomy popularization based on several rounds of teaching.

  6. Learning by Creating and Exchanging Objects: The SCY Experience

    ERIC Educational Resources Information Center

    De Jong, Ton; Van Joolingen, Wouter R.; Giemza, Adam; Girault, Isabelle; Hoppe, Ulrich; Kindermann, Jorg; Kluge, Anders; Lazonder, Ard W.; Vold, Vibeke; Weinberger, Armin; Weinbrenner, Stefan; Wichmann, Astrid; Anjewierden, Anjo; Bodin, Marjolaine; Bollen, Lars; D'Ham, Cedric; Dolonen, Jan; Engler, Jan; Geraedts, Caspar; Grosskreutz, Henrik; Hovardas, Tasos; Julien, Rachel; Lechner, Judith; Ludvigsen, Sten; Matteman, Yuri; Meistadt, Oyvind; Naess, Bjorge; Ney, Muriel; Pedaste, Margus; Perritano, Anthony; Rinket, Marieke; Von Schlanbusch, Henrik; Sarapuu, Tago; Schulz, Florian; Sikken, Jakob; Slotta, Jim; Toussaint, Jeremy; Verkade, Alex; Wajeman, Claire; Wasson, Barbara; Zacharia, Zacharias C.; Van Der Zanden, Martine

    2010-01-01

    Science Created by You (SCY) is a project on learning in science and technology domains. SCY uses a pedagogical approach that centres around products, called "emerging learning objects" (ELOs) that are created by students. Students work individually and collaboratively in SCY-Lab (the general SCY learning environment) on "missions" that are guided…

  7. Pressure Sounding of the Middle Atmosphere from ATMOS Solar Occultation Measurements of Atmospheric CO(sub 2) Absorption Lines

    NASA Technical Reports Server (NTRS)

    Abrams, M.; Gunson, M.; Lowes, L.; Rinsland, C.; Zander, R.

    1994-01-01

    A method for retrieving the atmospheric pressure corresponding to the tangent point of an infrared spectrum recorded in the solar occultation mode is described and applied to measurements made by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer. Tangent pressure values are inferred from measurements of isolated CO(sub 2) lines with temperature-insensitive intensities. Tangent pressures are determined with a spectroscopic precision of 1-3%, corresponding to a tangent point height precision, depending on the scale height, of 70-210 meters.

  8. High Excitation Rydberg Levels of Fe I from the ATMOS Solar Spectrum at 2.5 and 7 microns

    NASA Technical Reports Server (NTRS)

    Schoenfeld, W. G.; Chang, E. S.; Geller, M.; Johansson, S.; Nave, G.; Sauval, A. J.; Grevesse, N.

    1995-01-01

    The quadrupole-polarization theory has been applied to the 3d(sup 6)4S(D-6)4f and 5g subconfigurations of Fe I by a parametric fit, and the fitted parameters are used to predict levels in the 6g and 6h subconfigurations. Using the predicted values, we have computed the 4f-6g and 5g-6h transition arrays and made identifications in the ATMOS infrared solar spectrum. The newly identified 6g and 6h levels, based on ATMOS wavenumbers, are combined with the 5g levels and found to agree with the theoretical values with a root mean-squared-deviation of 0.042/ cm. Our approach yields a polarizability of 28.07 a(sub o, sup 2) and a quadrupole moment of 0.4360 +/- 0.0010 ea(sup 2, sub o) for Fe II, as well as an improved ionization potential of 63737.700 +/- 0.010/ cm for Fe I.

  9. ATMOS/ATLAS-3 Observations of Long-Lived Tracers and Descent in the Antarctic Vortex in November 1994

    NASA Technical Reports Server (NTRS)

    Abrams, M. C.; Manney, G. L.; Gunson, M. R.; Abbas, M. M.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Michelsen, H. A.; Newchurch, M. J.; Rinsland, C. P.; Salawitch, R. J.; Stiller, G. P.; Zander, R.

    1996-01-01

    Observations of the long-lived tracers N2O, CH4 and HF obtained by the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument in early November 1994 are used to estimate average descent rates during winter in the Antarctic polar vortex of 0.5 to 1.5 km/month in the lower stratosphere, and 2.5 to 3.5 km/month in the middle and upper stratosphere. Descent rates inferred from ATMOS tracer observations agree well with theoretical estimates obtained using radiative heating calculations. Air of mesospheric origin (N2O less than 5 ppbV) was observed at altitudes above about 25 km within the vortex. Strong horizontal gradients of tracer mixing ratios, the presence of mesospheric air in the vortex in early spring, and the variation with altitude of inferred descent rates indicate that the Antarctic vortex is highly isolated from midlatitudes throughout the winter from approximately 20 km to the stratopause. The 1994 Antarctic vortex remained well isolated between 20 and 30 km through at least mid-November.

  10. ATMOS/ATLAS 1 measurements of sulfur hexafluoride (SF6) in the lower stratosphere and upper troposphere

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Abrams, M. C.; Lowes, L. L.; Zander, R.; Mahieu, E.

    1993-01-01

    Vertical profiles of sulfur hexafluoride (SF6) in the lower stratosphere and upper troposphere have been retrieved from 0.01/cm resolution infrared solar occultation spectra recorded by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS (Atmospheric Laboratory for Applications and Science) 1 shuttle mission of March 24 to April 2, 1992. Based on measurements of the unresolved absorption by the SF6 mu(sub 3) band Q branch at 947.9/cm, average SF6 volume mixing ratios and 1-sigma uncertainties of 3.20 +/- 0.54 parts per trillion by volume (pptv; 10(exp -12) ppv) at 200 mbar (approximately 11.8 km) declining to 2.86 +/- 0.29 pptv at 100 mbar (approximately 16.2 km) and 1.95 +/- 0.50 pptv at 30 mbar (approximately 23.9 km) have been retrieved. The profiles show no obvious dependence with latitude over the range of the measurements (eight occultations spanning 28 deg S to 54 deg S). Assuming an exponential growth model and applying a correction for the interhemispheric concentration difference, an average SF6 rate of increase of 8.7 +/- 2.2% per year, 2 sigma, between 12 and 18 km has been derived by fitting the present measurements, ATMOS measurements from the April-May 1985 Spacelab 3 mission, and balloon-borne IR measurements obtained in March 1981 and June 1988.

  11. The Neurospora Transcription Factor ADV-1 Transduces Light Signals and Temporal Information to Control Rhythmic Expression of Genes Involved in Cell Fusion

    PubMed Central

    Dekhang, Rigzin; Wu, Cheng; Smith, Kristina M.; Lamb, Teresa M.; Peterson, Matthew; Bredeweg, Erin L.; Ibarra, Oneida; Emerson, Jillian M.; Karunarathna, Nirmala; Lyubetskaya, Anna; Azizi, Elham; Hurley, Jennifer M.; Dunlap, Jay C.; Galagan, James E.; Freitag, Michael; Sachs, Matthew S.; Bell-Pedersen, Deborah

    2016-01-01

    Light and the circadian clock have a profound effect on the biology of organisms through the regulation of large sets of genes. Toward understanding how light and the circadian clock regulate gene expression, we used genome-wide approaches to identify the direct and indirect targets of the light-responsive and clock-controlled transcription factor ADV-1 in Neurospora crassa. A large proportion of ADV-1 targets were found to be light- and/or clock-controlled, and enriched for genes involved in development, metabolism, cell growth, and cell fusion. We show that ADV-1 is necessary for transducing light and/or temporal information to its immediate downstream targets, including controlling rhythms in genes critical to somatic cell fusion. However, while ADV-1 targets are altered in predictable ways in Δadv-1 cells in response to light, this is not always the case for rhythmic target gene expression. These data suggest that a complex regulatory network downstream of ADV-1 functions to generate distinct temporal dynamics of target gene expression relative to the central clock mechanism. PMID:27856696

  12. Opening Comments: SciDAC 2008

    NASA Astrophysics Data System (ADS)

    Strayer, Michael

    2008-07-01

    Welcome to Seattle and the 2008 SciDAC Conference. This conference, the fourth in the series, is a continuation of the PI meetings we first began under SciDAC-1. I would like to start by thanking the organizing committee, and Rick Stevens in particular, for organizing this year's meeting. This morning I would like to look briefly at SciDAC, to give you a brief history of SciDAC and also look ahead to see where we plan to go over the next few years. I think the best description of SciDAC, at least the simulation part, comes from a quote from Dr Ray Orbach, DOE's Under Secretary for Science and Director of the Office of Science. In an interview that appeared in the SciDAC Review magazine, Dr Orbach said, `SciDAC is unique in the world. There isn't any other program like it anywhere else, and it has the remarkable ability to do science by bringing together physical scientists, mathematicians, applied mathematicians, and computer scientists who recognize that computation is not something you do at the end, but rather it needs to be built into the solution of the very problem that one is addressing'. Of course, that is extended not just to physical scientists, but also to biological scientists. This is a theme of computational science, this partnership among disciplines, which goes all the way back to the early 1980s and Ken Wilson. It's a unique thread within the Department of Energy. SciDAC-1, launched around the turn of the millennium, created a new generation of scientific simulation codes. It advocated building out mathematical and computing system software in support of science and a new collaboratory software environment for data. The original concept for SciDAC-1 had topical centers for the execution of the various science codes, but several corrections and adjustments were needed. The ASCR scientific computing infrastructure was also upgraded, providing the hardware facilities for the program. The computing facility that we had at that time was the big 3

  13. Concentrations of carbonyl sulfide and hydrogen cyanide in the free upper troposphere and lower stratosphere deduced from ATMOS/Spacelab 3 infrared solar occultation spectra

    NASA Technical Reports Server (NTRS)

    Zander, R.; Rinsland, C. P.; Russell, J. M., III; Farmer, C. B.; Norton, R. H.

    1988-01-01

    This paper presents the results on the volume mixing ratio profiles of carbonyl sulfide and hydrogen cyanide, deduced from the spectroscopic analysis of IR solar absorption spectra obtained in the occultation mode with the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument during its mission aboard Spacelab 3. A comparison of the ATMOS measurements for both northern and southern latitudes with previous field investigations at low midlatitudes shows a relatively good agreement. Southern Hemisphere volume mixing ratio profiles for both molecules were obtained for the first time, as were the profiles for the Northern Hemisphere covering the upper troposphere and the lower stratosphere simultaneously.

  14. Web life: Planet SciCast

    NASA Astrophysics Data System (ADS)

    2009-08-01

    So what is the site about? Planet SciCast is an online repository for short films about science - a bit like a science-specific, moderated version of YouTube. As of July 2009, the site hosts over 150 films on topics ranging from CERN's Large Hadron Collider to fun things to do with treacle. New content appears on the site every few weeks, and some films include links to information about related experiments, demos and activities. The site also runs an annual competition aimed at getting more people involved in making science films, with prizes in categories like "best original score" and "best presenter".

  15. Opening Remarks: SciDAC 2007

    NASA Astrophysics Data System (ADS)

    Strayer, Michael

    2007-09-01

    Good morning. Welcome to Boston, the home of the Red Sox, Celtics and Bruins, baked beans, tea parties, Robert Parker, and SciDAC 2007. A year ago I stood before you to share the legacy of the first SciDAC program and identify the challenges that we must address on the road to petascale computing—a road E E Cummins described as `. . . never traveled, gladly beyond any experience.' Today, I want to explore the preparations for the rapidly approaching extreme scale (X-scale) generation. These preparations are the first step propelling us along the road of burgeoning scientific discovery enabled by the application of X- scale computing. We look to petascale computing and beyond to open up a world of discovery that cuts across scientific fields and leads us to a greater understanding of not only our world, but our universe. As part of the President's America Competitiveness Initiative, the ASCR Office has been preparing a ten year vision for computing. As part of this planning the LBNL together with ORNL and ANL hosted three town hall meetings on Simulation and Modeling at the Exascale for Energy, Ecological Sustainability and Global Security (E3). The proposed E3 initiative is organized around four programmatic themes: Engaging our top scientists, engineers, computer scientists and applied mathematicians; investing in pioneering large-scale science; developing scalable analysis algorithms, and storage architectures to accelerate discovery; and accelerating the build-out and future development of the DOE open computing facilities. It is clear that we have only just started down the path to extreme scale computing. Plan to attend Thursday's session on the out-briefing and discussion of these meetings. The road to the petascale has been at best rocky. In FY07, the continuing resolution provided 12% less money for Advanced Scientific Computing than either the President, the Senate, or the House. As a consequence, many of you had to absorb a no cost extension for your

  16. Using SciDB to Support Photon Science Data Analysis

    SciTech Connect

    Becla, Jack; Wang, Daniel; lim, Kian-Tat; /SLAC

    2012-02-15

    Array data analytic systems like SciDB hold great potential to accelerate processing data from SLAC's Linac Coherent Light Source and other experiments. SciDB is unique in its ability to integrate storage and processing of array data efficiently, providing both space-efficient storage and out-of-memory efficient parallel array processing. We describe a recent effort to leverage SciDB to store and process LCLS data. The work includes development of software to import data into SciDB, subsequent benchmarks, and interactive manipulation of data in SciDB.

  17. First flight of the ATMOS instrument during the Spacelab 3 Mission, April 29 through May 6, 1985

    NASA Technical Reports Server (NTRS)

    Farmer, Crofton B.; Raper, Odell F.; Ocallaghan, Fred G.

    1987-01-01

    The underlying rationale and the implementation of the Atmospheric Trace Molecule Spectroscopy (ATMOS) investigation are discussed, a description of the sensor is given, and the ground tests and integration procedures leading to the Spacelab 3 flight are described. The data reduction and analysis procedures used after the flight are discussed, a number of examples of the spectra obtained are shown, and the concentration profiles as a function of altitude for the minor and trace gases measured during the mission are presented. On the basis of the instrument's ability to survive both the launch and the reentry of the shuttle and its flawless performance while on orbit, the concepts involved in the investigation have been proved by the Spacelab 3 flight, and an extended series of reflights is currently being planned as a part of the Atmospheric Laboratory for Applications and Science (ATLAS) Missions. The goals for the investigation during these missions are also discussed.

  18. SciDAC Institute for Ultrascale Visualization

    SciTech Connect

    Humphreys, Grigori R.

    2008-09-30

    The Institute for Ultrascale Visualization aims to address visualization needs of SciDAC science domains, including research topics in advanced scientific visualization architectures, algorithms, and interfaces for understanding large, complex datasets. During the current project period, the focus of the team at the University of Virginia has been interactive remote rendering for scientific visualization. With high-performance computing resources enabling increasingly complex simulations, scientists may desire to interactively visualize huge 3D datasets. Traditional large-scale 3D visualization systems are often located very close to the processing clusters, and are linked to them with specialized connections for high-speed rendering. However, this tight coupling of processing and display limits possibilities for remote collaboration, and prohibits scientists from using their desktop workstations for data exploration. In this project, we are developing a client/server system for interactive remote 3D visualization on desktop computers.

  19. Opening Comments: SciDAC 2009

    NASA Astrophysics Data System (ADS)

    Strayer, Michael

    2009-07-01

    Welcome to San Diego and the 2009 SciDAC conference. Over the next four days, I would like to present an assessment of the SciDAC program. We will look at where we've been, how we got to where we are and where we are going in the future. Our vision is to be first in computational science, to be best in class in modeling and simulation. When Ray Orbach asked me what I would do, in my job interview for the SciDAC Director position, I said we would achieve that vision. And with our collective dedicated efforts, we have managed to achieve this vision. In the last year, we have now the most powerful supercomputer for open science, Jaguar, the Cray XT system at the Oak Ridge Leadership Computing Facility (OLCF). We also have NERSC, probably the best-in-the-world program for productivity in science that the Office of Science so depends on. And the Argonne Leadership Computing Facility offers architectural diversity with its IBM Blue Gene/P system as a counterbalance to Oak Ridge. There is also ESnet, which is often understated—the 40 gigabit per second dual backbone ring that connects all the labs and many DOE sites. In the President's Recovery Act funding, there is exciting news that ESnet is going to build out to a 100 gigabit per second network using new optical technologies. This is very exciting news for simulations and large-scale scientific facilities. But as one noted SciDAC luminary said, it's not all about the computers—it's also about the science—and we are also achieving our vision in this area. Together with having the fastest supercomputer for science, at the SC08 conference, SciDAC researchers won two ACM Gordon Bell Prizes for the outstanding performance of their applications. The DCA++ code, which solves some very interesting problems in materials, achieved a sustained performance of 1.3 petaflops, an astounding result and a mark I suspect will last for some time. The LS3DF application for studying nanomaterials also required the development of a

  20. A test of the ADV-based Reynolds flux method for in situ estimation of sediment settling velocity in a muddy estuary

    NASA Astrophysics Data System (ADS)

    Cartwright, Grace M.; Friedrichs, Carl T.; Smith, S. Jarrell

    2013-12-01

    Under conditions common in muddy coastal and estuarine environments, acoustic Doppler velocimeters (ADVs) can serve to estimate sediment settling velocity ( w s) by assuming a balance between upward turbulent Reynolds flux and downward gravitational settling. Advantages of this method include simple instrument deployment, lack of flow disturbance, and relative insensitivity to biofouling and water column stratification. Although this method is being used with increasing frequency in coastal and estuarine environments, to date it has received little direct ground truthing. This study compared in situ estimates of w s inferred by a 5-MHz ADV to independent in situ observations from a high-definition video settling column over the course of a flood tide in the bottom boundary layer of the York River estuary, Virginia, USA. The ADV-based measurements were found to agree with those of the settling column when the current speed at about 40 cm above the bed was greater than about 20 cm/s. This corresponded to periods when the estimated magnitude of the settling term in the suspended sediment continuity equation was four or more times larger than the time rate of change of concentration. For ADV observations restricted to these conditions, ADV-based estimates of w s (mean 0.48±0.04 mm/s) were highly consistent with those observed by the settling column (mean 0.45±0.02 mm/s). However, the ADV-based method for estimating w s was sensitive to the prescribed concentration of the non-settling washload, C wash. In an objective operational definition, C wash can be set equal to the lowest suspended solids concentration observed around slack water.

  1. A millenium approach to Data Acquisition: SCI and PCI

    NASA Astrophysics Data System (ADS)

    Müller, Hans; Bogaerts, A.; Lindenstruth, V.

    The international SCI standard IEEE/ANSI 1596a [Ref. 1.] is on its way to become the computer interconnect of the year 2000 since for a first time, low latency desktop multiprocessing and cluster computing can be implemented at low cost. The PCI bus is todays's dominating local bus extension for all major computer platforms as well as for buses like VMEbus. PCI is a self configuring memory and I/O system for peripheral components with a hierarchical architecture. SCI is a scalable, bus-like interconnect for distributed processors and memories. It allows for optionally coherent data caching and assures errorfree data delivery. First measurement with commercial SCI products (SBUS-SCI) confirm simulations that SCI can handle even the highest data rates of LHC experiments. The eventbuilder layer for a millenium very high rate DAQ system can therefore be viewed as a SCI network ( bridges, cables & switches) interfaced between PCI buses on the frontend (VMEb ) side and on the processor farm ( Multi-CPU) side. Such a combination of SCI and PCI enables PCI-PCI memory access, transparently across SCI. It also allows for a novel, low level trigger technique: the trigger algorithm can access VME data buffers with bus-like latencies like local memory, i.e. full data transfers become redundent. The first prototype of a PCI-SCI bridge for DAQ is presented as starting point for a test system with built-in scalability.

  2. Pressure sounding of the middle atmosphere from ATMOS solar occultation measurements of atmospheric CO(2) absorption lines.

    PubMed

    Abrams, M C; Gunson, M R; Lowes, L L; Rinsland, C P; Zander, R

    1996-06-01

    A method for retrieving the atmospheric pressure corresponding to the tangent point of an infrared spectrum recorded in the solar occultation mode is described and applied to measurements made by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier-transform spectrometer. Tangent pressure values are inferred from measurements of isolated CO(2) lines with temperature-insensitive strengths by measuring the slant-column CO(2) amount and by adjusting the viewing geometry until the calculated column matches the observed column. Tangent pressures are determined with a spectroscopic precision of l%-3%, corresponding to a tangent-point height precision of 70-210 m. The total uncertainty is limited primarily by the quality of the spectra and ranges between 4% and 6% (280-420 m) for spectra with signal-to-noise ratios of 300:1 and between 4% and 10% for spectra with signal-to-noise ratios of 100:1. The retrieval of atmospheric pressure increases the accuracy of the retrieved-gas concentrations by minimizing the effect of systematic errors introduced by climatological pressure data, ephemeris parameters, and the uncertainties in instrumental pointing.

  3. Atmos/Atlas 3 Infrared Profile Measurements of Trace Gases in The November 1994 Tropical and Subtropical Upper Troposphere

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Wang, P.-H.; Arduini, R. F.; Baum, B. A.; Minnis, P.; Minnis, P.; Goldman, A.; Abrams, M. C.; Zander, R.; Mahieu, E.; Mahieu, E.; Salawitch, R. J.; Michelsen, H. A.; Irion, F. W.; Newchurch, M. J.

    1998-01-01

    Vertical mixing ratio profiles of four relatively long-lives gases, HCN, C2H2, CO, and C2H6, have been retrieved from 0.01/cm resolution infrared solar occultation spectra recorded between latitudes of 5.3degN and 31.4degN. The observations were obtained by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the Atmospheric Laboratory for Applications and Science (ATLAS) 3 shuttle flight, 3-12 November 1994. Elevated mixing ratios below the tropopause were measured for these gases during several of the occultations. The positive correlations obtained between the simultaneously measured mixing ratios suggest that the enhancements are likely the result of surface emissions, most likely biomass burning and/or urban industrial activities, followed by common injection via deep convective transport of the gases to the upper troposphere. The elevated levels of HCN may account for at least part of the "missing NO," in the upper troposphere. Comparisons of the observations with values measured during a recent aircraft campaign are presented.

  4. ATMOS/ATLAS-3 Measurements of Stratospheric Chlorine and Reactive Nitrogen Partitioning Inside and Outside the November 1994 Antarctic Vortex

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Salawitch, R. J.; Michelsen, H. A.; Zander, R.; Newchurch, M. J.; Abbas, M. M.; Abrams, M. C.; Manney, G. L.; Chang, A. Y.; Irion, F. W.; Goldman, A.; Mahieu, E.

    1996-01-01

    Partitioning between HCl and ClONO2 and among the main components of the reactive nitrogen family (NO, NO2, HNO3, ClONO2, N2O5, and HO2NO2) has been studied inside and outside the Antarctic stratospheric vortex based on ATMOS profiles measured at sunrise during the 3-12 November 1994 ATLAS-3 Shuttle mission. Elevated mixing ratios of HCl in the lower stratosphere with a peak of approximately 2.9 ppbv (10(exp -9) parts per volume) were measured inside the vortex near 500 K potential temperature (approximately 19 km). Maximum ClONO2 mixing ratios of approximately 1.2, approximately 1.4, and approximately 0.9 ppbv near 700 K (approximately 25 km) were measured inside, at the edge, and outside the vortex, respectively. Model calculations reproduce the higher levels of HCl and NO(x) (NO + NO2) inside the lower stratospheric vortex both driven by photochemical processes initiated by low O3. The high HCl at low O3 results from chemical production of HC1 via the reaction of enhanced Cl with CH4, limited production of ClONO2, and the descent of inorganic chlorine from higher altitudes.

  5. Atmospheric Chemistry Experiment (ACE) Lower Stratospheric Trend Measurements: Approach and Preliminary Results based on Comparisons with ATMOS Midlatitude Observations

    NASA Astrophysics Data System (ADS)

    Rinsland, C. P.; Bernath, P. F.; McLeod, S.; Boone, C.; McHugh, M.; Walker, K.

    2003-12-01

    The Atmospheric Chemistry Experiment (ACE) was successfully launched on August 12, 2003, into a 73.9 degree inclined orbit at an altitude of 650 km onboard a U.S.-supplied Pegasus XL vehicle. The primary goal of the ACE mission is to measure solar occultation spectra from the UV to mid-infrared for a minimum of two years to determine whether or not the stratospheric ozone layer will begin to recover now that chlorofluorocarbon emissions have been banned. Among the instruments carried by the small Canadian-built satellite is a compact Fourier transform spectrometer designed to measure in the 750-4100 cm-1 region at 0.02 cm-1 spectral resolution. The measurements will provide an opportunity to determine lower stratospheric trends at midlatitudes by comparison of ACE measurements with measurements recorded by the Atmospheric Trace MOlecule Spectroscopy (ATMOS) Fourier transform spectometer at 0.01-cm-1 resolution during its first shuttle flight in 1985. We describe the approach to be used for trend determination, the status of the investigation, and the other data relevant for comparisons.

  6. SciDB and Geoinformatics Analysis

    NASA Astrophysics Data System (ADS)

    Brown, Paul

    2015-04-01

    The SciDB project took as its design goals a list of features identified as being critical to scientific data management in a survey of working scientists (Stonebraker et al 2009). Earth scientists working with remote sensing data were well represented among those polled so it should come as no surprise that the platform has been embraced by that community. In this talk we focus on work done by researchers at NASA and INPE, and on applications created by commercial data providers in Korea and the United States. For each use-case, we will review the project team's objectives, the nature and quantity of the data involved, the their workload queries. As we discuss each use-case we will describe what is emerging as "best practice" for data management and analysis in this space. M. Stonebraker, J. Becla, D. J. DeWitt, K. T. Lim, D. Maier, O. Ratzesberger, and S. B. Zdonik. Requirements for science data bases and scidb. In CIDR 2009, Fourth Biennial Conference on Innovative Data Systems Research, Asilomar, CA, USA, January 4-7, 2009, Online Proceedings, 2009.

  7. Experiences using SciPy for computer vision research

    SciTech Connect

    Eads, Damian R; Rosten, Edward J

    2008-01-01

    SciPy is an effective tool suite for prototyping new algorithms. We share some of our experiences using it for the first time to support our research in object detection. SciPy makes it easy to integrate C code, which is essential when algorithms operating on large data sets cannot be vectorized. The universality of Python, the language in which SciPy was written, gives the researcher access to a broader set of non-numerical libraries to support GUI development, interface with databases, manipulate graph structures. render 3D graphics, unpack binary files, etc. Python's extensive support for operator overloading makes SciPy's syntax as succinct as its competitors, MATLAB, Octave, and R. More profoundly, we found it easy to rework research code written with SciPy into a production application, deployable on numerous platforms.

  8. Work Domain Analysis of a Predecessor Sodium-cooled Reactor as Baseline for AdvSMR Operational Concepts

    SciTech Connect

    Ronald Farris; David Gertman; Jacques Hugo

    2014-03-01

    This report presents the results of the Work Domain Analysis for the Experimental Breeder Reactor (EBR-II). This is part of the phase of the research designed to incorporate Cognitive Work Analysis in the development of a framework for the formalization of an Operational Concept (OpsCon) for Advanced Small Modular Reactors (AdvSMRs). For a new AdvSMR design, information obtained through Cognitive Work Analysis, combined with human performance criteria, can and should be used in during the operational phase of a plant to assess the crew performance aspects associated with identified AdvSMR operational concepts. The main objective of this phase was to develop an analytical and descriptive framework that will help systems and human factors engineers to understand the design and operational requirements of the emerging generation of small, advanced, multi-modular reactors. Using EBR-II as a predecessor to emerging sodium-cooled reactor designs required the application of a method suitable to the structured and systematic analysis of the plant to assist in identifying key features of the work associated with it and to clarify the operational and other constraints. The analysis included the identification and description of operating scenarios that were considered characteristic of this type of nuclear power plant. This is an invaluable aspect of Operational Concept development since it typically reveals aspects of future plant configurations that will have an impact on operations. These include, for example, the effect of core design, different coolants, reactor-to-power conversion unit ratios, modular plant layout, modular versus central control rooms, plant siting, and many more. Multi-modular plants in particular are expected to have a significant impact on overall OpsCon in general, and human performance in particular. To support unconventional modes of operation, the modern control room of a multi-module plant would typically require advanced HSIs that would

  9. Middle and upper atmosphere pressure-temperature profiles and the abundances of CO2 and CO in the upper atmosphere from ATMOS/Spacelab 3 observations

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Zander, R.; Lopez-Puertas, M.

    1992-01-01

    An improved method for retrieving pressure-temperature profiles is described and is used to retrieve profiles of the kinetic-temperature and atmospheric-pressure profiles between 20 and 116 km altitudes and the CO2 and CO volume-mixing ratios between 70 and 116 km, using the IR occultation spectra recorded by the Spacelab 3 atmospheric trace molecular spectroscopy (ATMOS) Fourier transform spectrometer between April 29 and May 6, 1985. Profiles are derived for six ATMOS occultations. The CO2 and CO volume-mixing profiles are compared with previous observations and model predictions. Evidence is found for vibrational non-LTE by analyzing the lines of the (nu-2 + nu-3 - nu-2) (C-12)(O-16) band. Results are used for deriving (C-12)(O-16) (010) vibrational temperatures, which are compared with the retrieved kinetic temperatures and the predictions of non-LTE effects by recent models.

  10. Seasonal Variations of Water Vapor in the Lower Stratosphere Inferred from ATMOS/ATLAS-3 Measurements of H(sub 2)O and CH(sub 4)

    NASA Technical Reports Server (NTRS)

    Abbas, M. M.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Newchurch, M. J.; Salawitch, R. J.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Manney, G. L.; Moyer, E. J.; Nagaraju, R.; Rinsland, C. P.; Stiller, G. P.; Zander, R.

    1996-01-01

    Stratospheric measurements of H(sub 2)O and CH(sub 4) by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer on the ATLAS-3 Shuttle flight in November 1994 have been used to investigate the altitude and geographic variability of H(sub 2)O and the quantity H(Eta?) = (H(sub 2)O + CH(sub 4)) in the tropics and at mid-latitudes (8-49in the northern hemisphere.

  11. 75 FR 24747 - SCI, LLC/Zener-Rectifier Operations Division A Wholly Owned Subsidiary of SCI, LLC/ON...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Phoenix, AZ; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In... of SCI, LLC/ON Semiconductor, Phoenix, Arizona. The notice was published in the Federal Register on... at the Phoenix Arizona location of SCI LLC/Zener-Rectifier, Operations Division, a wholly...

  12. Status of FNAL SciBooNE experiment

    SciTech Connect

    Nakajima, Yasuhiro; /Kyoto U.

    2007-12-01

    SciBooNE is a new experiment at FNAL which will make precision neutrino-nucleus cross section measurements in the one GeV region. These measurements are essential for the future neutrino oscillation experiments. We started data taking in the antineutrino mode on June 8, 2007, and collected 5.19 x 10{sup 19} protons on target (POT) before the accelerator shutdown in August. The first data from SciBooNE are reported in this article.

  13. Introduction to Searching with SciFinder Scholar

    NASA Astrophysics Data System (ADS)

    Ridley, Damon D.

    2001-04-01

    With SciFinder Scholar now one of the preferred access routes to information in the sciences, many college information retrieval courses that dealt with online networks need to be redesigned. Although one of the basic assumptions within the design of SciFinder Scholar is that staff and students may retrieve valuable answers with little training, nevertheless, with a little instruction improved search results may be obtained. We present here our basic teaching program for senior undergraduate and postgraduate classes.

  14. A Method of Successive Corrections of the Control Subspace in the Reduced-Order Variational Data Assimilation

    DTIC Science & Technology

    2009-02-01

    and M. Kamachi, 2002: The improvement made by a modified TLM in 4DVar with a geophysical boundary layer model . Adv. Atmos. Sci., 19 (4), 563–582...into numerical models is proposed. In contrast to the conventional 4DVAR schemes, the method does not require development of the tangent linear and... model utilized as a strong constraint. When the adjoint code is stable, R4DVAR’s convergence rate is comparable to that of the standard 4DVAR

  15. MODFLOW-2000 : the U.S. Geological Survey modular ground-water model--documentation of the Advective-Transport Observation (ADV2) Package

    USGS Publications Warehouse

    Anderman, Evan R.; Hill, Mary Catherine

    2001-01-01

    Observations of the advective component of contaminant transport in steady-state flow fields can provide important information for the calibration of ground-water flow models. This report documents the Advective-Transport Observation (ADV2) Package, version 2, which allows advective-transport observations to be used in the three-dimensional ground-water flow parameter-estimation model MODFLOW-2000. The ADV2 Package is compatible with some of the features in the Layer-Property Flow and Hydrogeologic-Unit Flow Packages, but is not compatible with the Block-Centered Flow or Generalized Finite-Difference Packages. The particle-tracking routine used in the ADV2 Package duplicates the semi-analytical method of MODPATH, as shown in a sample problem. Particles can be tracked in a forward or backward direction, and effects such as retardation can be simulated through manipulation of the effective-porosity value used to calculate velocity. Particles can be discharged at cells that are considered to be weak sinks, in which the sink applied does not capture all the water flowing into the cell, using one of two criteria: (1) if there is any outflow to a boundary condition such as a well or surface-water feature, or (2) if the outflow exceeds a user specified fraction of the cell budget. Although effective porosity could be included as a parameter in the regression, this capability is not included in this package. The weighted sum-of-squares objective function, which is minimized in the Parameter-Estimation Process, was augmented to include the square of the weighted x-, y-, and z-components of the differences between the simulated and observed advective-front locations at defined times, thereby including the direction of travel as well as the overall travel distance in the calibration process. The sensitivities of the particle movement to the parameters needed to minimize the objective function are calculated for any particle location using the exact sensitivity

  16. On the Assessment and Uncertainty of Atmospheric Trace Gas Burden Measurements with High Resolution Infrared Solar Occultation Spectra from Space by the ATMOS Experiment

    NASA Technical Reports Server (NTRS)

    Abrams, M. C.; Chang, A. Y.; Gunson, M. R.; Abbas, M. M.; Goldman, A.; Irion, F. W.; Michelsen, H. A.; Newchurch, M. J.; Rinsland, C. P.; Stiller, G. P.; Zander, R.

    1996-01-01

    The Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument is a high resolution Fourier transform spectrometer that measures atmospheric composition from low Earth orbit with infrared solar occultation sounding in the limb geometry. Following an initial flight in 1985, ATMOS participated in the Atmospheric Laboratory for Applications and Science (ATLAS) 1, 2, and 3 Space Shuttle missions in 1992, 1993, and 1994 yielding a total of 440 occultation measurements over a nine year period. The suite of more than thirty atmospheric trace gases profiled includes CO2, O3, N2O, CH4, H2O, NO, NO2, HNO3, HCl, HF, ClONO2, CCl3F, CCl2F2, CHF2Cl, and N2O5. The analysis method has been revised throughout the mission years culminating in the 'version 2' data set. The spectroscopic error analysis is described in the context of supporting the precision estimates reported with the profiles; in addition, systematic uncertainties assessed from the quality of the spectroscopic database are described and tabulated for comparisons with other experiments.

  17. Seasonal Variations of Water Vapor in the Lower Stratosphere Inferred from ATMOS/ATLAS-3 Measurements of H2O and CH4

    NASA Technical Reports Server (NTRS)

    Abbas, M. M.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Newchurch, M. J.; Salawitch, R. J.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Manney, G. L.; Moyer, E. J.; Nagaraju, R.; Rinsland, C. P.; Stiller, G. P.; Zander, R.

    1996-01-01

    Stratospheric measurements of H2O and CH4 by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer on the ATLAS-3 shuttle flight in November 1994 have been examined to investigate the altitude and geographic variability of H2O and the quantity H = (H2O + 2CH4) in the tropics and at mid-latitudes (8 to 49 deg N) in the northern hemisphere. The measurements indicate an average value of 7.24 +/- 0.44 ppmv for H between altitudes of about 18 to 35 km, corresponding to an annual average water vapor mixing ratio of 3.85 +/- 0.29 ppmv entering the stratosphere. The H2O vertical distribution in the tropics exhibits a wave-like structure in the 16- to 25-km altitude range, suggestive of seasonal variations in the water vapor transported from the troposphere to the stratosphere. The hygropause appears to be nearly coincident with the tropopause at the time of observations. This is consistent with the phase of the seasonal cycle of H2O in the lower stratosphere, since the ATMOS observations were made in November when the H2O content of air injected into the stratosphere from the troposphere is decreasing from its seasonal peak in July-August.

  18. ATMOS Measurements of H2O + 2CH4 and Total Reactive Nitrogen in the November 1994 Antarctic Stratosphere: Dehydration and Denitrification in the Vortex

    NASA Technical Reports Server (NTRS)

    Rinsland, C. P.; Gunson, M. R.; Salawitch, R. J.; Newchurch, M. J.; Zander, R.; Abbas, M. M.; Abrams, M. C.; Manney, G. L.; Michelsen, H. A.; Chang, A. Y.; Goldman, A.

    1996-01-01

    Simultaneous stratospheric volume mixing ratios (VMR's) measured inside and outside the Antarctic vortex by the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument in November 1994 reveal previously unobserved features in the distributions of total reactive nitrogen (NO(y)) and total hydrogen (H2O + 2CH4). Maximum removal of NO(y) due to sedimentation of polar stratospheric clouds (PSC's) inside the vortex occurred at a potential temperature (Theta) of 500-525 K (approximately 20 km), where values were 5 times smaller than measurements outside. Maximum loss of H2O + 2CH4 due to PSC's occurred in the vortex at 425-450 K, approximately 3 km lower than the peak NO(y) loss. At that level, H2O + 2CH4 VMR's inside the vortex were approximately 70% of corresponding values outside. The Antarctic and April 1993 Arctic measurements by ATMOS show no significant differences in H2O + 2CH4 VMR's outside the vortices in the two hemispheres. Elevated NO(y) VMRs were measured inside the vortex near 700 K. Recent model calculations indicate that this feature results from downward transport of elevated NO(y) produced in the thermosphere and mesosphere.

  19. Seasonal Variations of Water Vapor in the Lower Stratosphere Inferred from ATMOS/ATLAS-3 Measurements of H2O and CH4

    NASA Technical Reports Server (NTRS)

    Abbas, M. M.; Michelsen, H. A.; Gunson, M. R.; Abrams, M. C.; Newchurch, M. J.; Salawitch, R. J.; Chang, A. Y.; Goldman, A.; Irion, F. W.; Manney, G. L.; Moyer, E. J.; Nagaraju, R.; Rinsland, C. P.; Stiller, G. P.; Zander, R.

    1996-01-01

    Stratospheric measurements of H2O and CH4 by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer on the ATLAS-3 shuttle flight in November 1994 have been examined to investigate the altitude and geographic variability of H2O and the quantity H = (H2O + 2CH4) in the tropics and at mid-latitudes (8 to 49 deg N) in the northern hemisphere. The measurements indicate an average value of 7.24 plus or minus 0.44 ppmv for H between altitudes of about 18 to 35 km, corresponding to an annual average water vapor mixing ratio of 3.85 plus or minus 0.29 ppmv entering the stratosphere. The H2O vertical distribution in the tropics exhibits a wave-like structure in the 16- to 25-km altitude range, suggestive of seasonal variations in the water vapor transported from the troposphere to the stratosphere. The hygropause appears to be nearly coincident with the tropopause at the time of observations. This is consistent with the phase of the seasonal cycle of H2O in the lower stratosphere, since the ATMOS observations were made in November when the H2O content of air injected into the stratosphere from the troposphere is decreasing from its seasonal peak in July - August.

  20. Solving Large-scale Eigenvalue Problems in SciDACApplications

    SciTech Connect

    Yang, Chao

    2005-06-29

    Large-scale eigenvalue problems arise in a number of DOE applications. This paper provides an overview of the recent development of eigenvalue computation in the context of two SciDAC applications. We emphasize the importance of Krylov subspace methods, and point out its limitations. We discuss the value of alternative approaches that are more amenable to the use of preconditioners, and report the progression using the multi-level algebraic sub-structuring techniques to speed up eigenvalue calculation. In addition to methods for linear eigenvalue problems, we also examine new approaches to solving two types of non-linear eigenvalue problems arising from SciDAC applications.

  1. SciTech Clubs for Girls. [Annual] technical report

    SciTech Connect

    Nogal, A.M.

    1993-02-01

    Since January 1992, 9 exhibits have been constructed by the SciTech Clubs for Girls, which involved 63 girls, ages 10 to 14. These exhibits are: Bubble Shapes by the St. Charles Cadette Girl Scout Troop No. 109. Density Games by the South Elgin Cadette Girl Scout Troop No. 132. Electric Fleas by the Warrenville Junior Girl Scout Troop No. 305. Energy vs. Power by the Aurora Junior Girl Scout Troop No. 242. The Organ Pipe by the Bartlett Junior Girl Scout Troop No. 107. Ohm`s Law by the Geneva Junior Girl Scout Troop No. 401. What is Gravity by the Pilsen YMCA girls. Insulation at Work by the Algonquin Junior Girl Scout Troop No. 303. Series vs. Parallel by the Leland Junior Girl Scout Troop No. 50. The report is a description of each exhibit and the group that built the exhibit. Each group had a minimum of 10 hours of contact time at SciTech with the SciTech Clubs for Girls Program Coordinator. All mentors are female. Each exhibit building experience includes a trip to the hardware store to purchase supplies. After the exhibit is complete, the girls receive certificates of achievement and a SciTech Club Patch.

  2. Combined SCI and TBI: recovery of forelimb function after unilateral cervical spinal cord injury (SCI) is retarded by contralateral traumatic brain injury (TBI), and ipsilateral TBI balances the effects of SCI on paw placement.

    PubMed

    Inoue, Tomoo; Lin, Amity; Ma, Xiaokui; McKenna, Stephen L; Creasey, Graham H; Manley, Geoffrey T; Ferguson, Adam R; Bresnahan, Jacqueline C; Beattie, Michael S

    2013-10-01

    A significant proportion (estimates range from 16 to 74%) of patients with spinal cord injury (SCI) have concomitant traumatic brain injury (TBI), and the combination often produces difficulties in planning and implementing rehabilitation strategies and drug therapies. For example, many of the drugs used to treat SCI may interfere with cognitive rehabilitation, and conversely drugs that are used to control seizures in TBI patients may undermine locomotor recovery after SCI. The current paper presents an experimental animal model for combined SCI and TBI to help drive mechanistic studies of dual diagnosis. Rats received a unilateral SCI (75 kdyn) at C5 vertebral level, a unilateral TBI (2.0 mm depth, 4.0 m/s velocity impact on the forelimb sensori-motor cortex), or both SCI+TBI. TBI was placed either contralateral or ipsilateral to the SCI. Behavioral recovery was examined using paw placement in a cylinder, grooming, open field locomotion, and the IBB cereal eating test. Over 6weeks, in the paw placement test, SCI+contralateral TBI produced a profound deficit that failed to recover, but SCI+ipsilateral TBI increased the relative use of the paw on the SCI side. In the grooming test, SCI+contralateral TBI produced worse recovery than either lesion alone even though contralateral TBI alone produced no observable deficit. In the IBB forelimb test, SCI+contralateral TBI revealed a severe deficit that recovered in 3 weeks. For open field locomotion, SCI alone or in combination with TBI resulted in an initial deficit that recovered in 2 weeks. Thus, TBI and SCI affected forelimb function differently depending upon the test, reflecting different neural substrates underlying, for example, exploratory paw placement and stereotyped grooming. Concurrent SCI and TBI had significantly different effects on outcomes and recovery, depending upon laterality of the two lesions. Recovery of function after cervical SCI was retarded by the addition of a moderate TBI in the contralateral

  3. Combined SCI and TBI: Recovery of forelimb function after unilateral cervical spinal cord injury (SCI) is retarded by contralateral traumatic brain injury (TBI), and ipsilateral TBI balances the effects of SCI on paw placement

    PubMed Central

    Inoue, Tomoo; Lin, Amity; Ma, Xiaokui; McKenna, Stephen L.; Creasey, Graham H.; Manley, Geoffrey T.; Ferguson, Adam R.; Bresnahan, Jacqueline C.; Beattie, Michael S.

    2015-01-01

    A significant proportion (estimates range from 16–74%) of patients with spinal cord injury (SCI) have concomitant traumatic brain injury (TBI), and the combination often produces difficulties in planning and implementing rehabilitation strategies and drug therapies. For example, many of the drugs used to treat SCI may interfere with cognitive rehabilitation, and conversely drugs that are used to control seizures in TBI patients may undermine locomotor recovery after SCI. The current paper presents an experimental animal model for combined SCI and TBI to help drive mechanistic studies of dual diagnosis. Rats received a unilateral SCI (75 kdyn) at C5 vertebral level, a unilateral TBI (2.0 mm depth, 4.0 m/s velocity impact on the forelimb sensori-motor cortex), or both SCI + TBI. TBI was placed either contralateral or ipsilateral to the SCI. Behavioral recovery was examined using paw placement in a cylinder, grooming, open field locomotion, and the IBB cereal eating test. Over 6 weeks, in the paw placement test, SCI + contralateral TBI produced a profound deficit that failed to recover, but SCI + ipsilateral TBI increased the relative use of the paw on the SCI side. In the grooming test, SCI + contralateral TBI produced worse recovery than either lesion alone even though contralateral TBI alone produced no observable deficit. In the IBB forelimb test, SCI + contralateral TBI revealed a severe deficit that recovered in 3 weeks. For open field locomotion, SCI alone or in combination with TBI resulted in an initial deficit that recovered in 2 weeks. Thus, TBI and SCI affected forelimb function differently depending upon the test, reflecting different neural substrates underlying, for example, exploratory paw placement and stereotyped grooming. Concurrent SCI and TBI had significantly different effects on outcomes and recovery, depending upon laterality of the two lesions. Recovery of function after cervical SCI was retarded by the addition of a moderate TBI in the

  4. Overview of the Scalable Coherent Interface, IEEE STD 1596 (SCI)

    SciTech Connect

    Gustavson, D.B.; James, D.V.; Wiggers, H.A.

    1992-10-01

    The Scalable Coherent Interface standard defines a new generation of interconnection that spans the full range from supercomputer memory `bus` to campus-wide network. SCI provides bus-like services and a shared-memory software model while using an underlying, packet protocol on many independent communication links. Initially these links are 1 GByte/s (wires) and 1 GBit/s (fiber), but the protocol scales well to future faster or lower-cost technologies. The interconnect may use switches, meshes, and rings. The SCI distributed-shared-memory model is simple and versatile, enabling for the first time a smooth integration of highly parallel multiprocessors, workstations, personal computers, I/O, networking and data acquisition.

  5. Distributed job scheduling in SCI Local Area MultiProcessors

    SciTech Connect

    Agasaveeran, S.; Li, Qiang

    1996-12-31

    Local Area MultiProcessors (LAMP) is a network of personal workstations with distributed shared physical memory provided by high performance technologies such as SCI. LAMP is more tightly coupled than the traditional local area networks (LAN) but is more loosely coupled than the bus based multiprocessors. This paper presents a distributed scheduling algorithm which exploits the distributed shared memory in SCI-LAMP to schedule the idle remote processors among the requesting workstations. It considers fairness by allocating remote processing capacity to the requesting workstations based on their priorities according to the decay-usage scheduling approach. The performance of the algorithm in scheduling both sequential and parallel jobs is evaluated by simulation. It is found that the higher priority nodes achieve faster job response times and higher speedups than that of the lower priority nodes. Lower scheduling overhead allows finer granularity of remote processors sharing than in LAN.

  6. Molecular Determinants Fundamental to Axon Regeneration after SCI

    DTIC Science & Technology

    2013-10-01

    adult zebrafish (Specific Aim 1). We also will examine in vivo the role of PTP σ in inhibition of axon regeneration (Specific Aim 2). In addition, we...AWARD NUMBER: W81XWH-11-1-0645 TITLE: Molecular Determinants Fundamental to Axon Regeneration ... Regeneration after SCI 5b. GRANT NUMBER W81XWH-11-1-0645 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Jeffrey Alan Plunkett, Ph.D

  7. Utilization of SciFinder Scholar at an Undergraduate Institution

    NASA Astrophysics Data System (ADS)

    O'Reilly, Stacy A.; Wilson, Anne M.; Howes, Barbara

    2002-04-01

    The use of tools to search chemical information databases continues to be important to science educators. The ability to perform online searches of Chemical Abstracts Service can have a significant impact on teaching and research. The implementation of SciFinder Scholar at Butler University has resulted in significant changes in teaching, student-based research, and faculty development in the Chemistry Department. Details of these changes in courses, student research projects and proposals, and the professional growth of the faculty are discussed.

  8. Online Registries for Researchers: Using ORCID and SciENcv.

    PubMed

    Vrabel, Mark

    2016-12-01

    The Open Researcher and Contributor ID (ORCID) registry helps resolve name ambiguity by assigning persistent unique identifiers that automatically link to a researcher's publications, grants, and other activities. This article provides an overview of ORCID and its benefits, citing several examples of its use in cancer and nursing journals. The article also briefly describes My NCBI and the Science Experts Network Curriculum Vitae (SciENcv) and its connection to ORCID.

  9. An Implantable Neuroprosthetic Device to Normalize Bladder Function after SCI

    DTIC Science & Technology

    2014-12-01

    experiments using cats . These results have laid the foundation for us to further design and develop an implantable stimulator for human application in...experiments using cats . These results have laid the foundation for us to further design and develop this implantable stimulator into human application in...stimulator system Our previous studies [1-4] in anesthetized chronic SCI cats showed that blocking pudendal nerves using high-frequency (6-10 kHz

  10. 75 FR 19626 - Notice of Intent To Grant Exclusive Patent License: SciTech Medical Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... Exclusive Patent License: SciTech Medical Inc. AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY... SciTech Medical Inc. The proposed license is a revocable, nonassignable, partially exclusive...

  11. OPENING REMARKS: SciDAC: Scientific Discovery through Advanced Computing

    NASA Astrophysics Data System (ADS)

    Strayer, Michael

    2005-01-01

    Good morning. Welcome to SciDAC 2005 and San Francisco. SciDAC is all about computational science and scientific discovery. In a large sense, computational science characterizes SciDAC and its intent is change. It transforms both our approach and our understanding of science. It opens new doors and crosses traditional boundaries while seeking discovery. In terms of twentieth century methodologies, computational science may be said to be transformational. There are a number of examples to this point. First are the sciences that encompass climate modeling. The application of computational science has in essence created the field of climate modeling. This community is now international in scope and has provided precision results that are challenging our understanding of our environment. A second example is that of lattice quantum chromodynamics. Lattice QCD, while adding precision and insight to our fundamental understanding of strong interaction dynamics, has transformed our approach to particle and nuclear science. The individual investigator approach has evolved to teams of scientists from different disciplines working side-by-side towards a common goal. SciDAC is also undergoing a transformation. This meeting is a prime example. Last year it was a small programmatic meeting tracking progress in SciDAC. This year, we have a major computational science meeting with a variety of disciplines and enabling technologies represented. SciDAC 2005 should position itself as a new corner stone for Computational Science and its impact on science. As we look to the immediate future, FY2006 will bring a new cycle to SciDAC. Most of the program elements of SciDAC will be re-competed in FY2006. The re-competition will involve new instruments for computational science, new approaches for collaboration, as well as new disciplines. There will be new opportunities for virtual experiments in carbon sequestration, fusion, and nuclear power and nuclear waste, as well as collaborations

  12. Orthostatic Responses to Anticholinesterase Inhibition in Persons with SCI

    PubMed Central

    Wecht, Jill M.; Cirnigliaro, Christopher M.; Azarelo, Frank; Bauman, William A.; Kirshblum, Steven C.

    2015-01-01

    Acetylcholine (Ach) is the pre-synaptic neurotransmitter of the sympathetic nervous system. Increased pre-synaptic Ach may augment post-synaptic release of norepinephrine thereby increasing systemic blood pressure (BP). The primary objective of this investigation was to determine the hemodynamic effect of pyridostigmine bromide (PYRIDO: 60 mg), an Ach inhibitor (AchI), compared to no-drug (NO-D) during head-up tilt (HUT) in individuals with spinal cord injury (SCI). Secondarily we aimed to determine the effects of PYRIDO compared to NO-D on symptoms of orthostatic intolerance (OI) and adverse event reporting (AE). Ten individuals with SCI (C4–C7) were studied on 2 occasions: visit 1) NO-D and visit 2) PYRIDO. On each visit subjects underwent a progressive HUT maneuver to 15°, 25°, 35° for 5 minutes at each angle and 45 minutes at 45°. Supine and orthostatic heart rate (HR), systolic and diastolic BP (SBP & DBP) were monitored and symptoms of OI and AE recorded. Supine hemodynamics did not differ between the trials. The significant fall in SBP during the NO-D trial was diminished with PYRIDO and five subjects had an increased DBP during HUT with PYRIDO compared to the NO-D trial. Individuals that responded to PYRIDO with an increase in orthostatic BP had significantly lower resting HR than non-responders (p<0.01), which suggests increased levels of pre-synaptic Ach. Subjective symptoms of OI and AE reporting did not differ between the two trials. These preliminary data suggest that PYRIDO is safe and may be effective at ameliorating the orthostatic fall in BP in select individuals with SCI. PMID:25916633

  13. Nuclear Physics in the SciDAC Era

    SciTech Connect

    Robert Edwards

    2009-08-01

    Lattice QCD currently provides our only means of solving QCD (Quantum Chromo Dynamics) -- the theory of the strong nuclear force -- in the low-energy regime, and thus of crucial importance for theoretical and experimental research programs in High Energy and Nuclear Physics. Under the SciDAC program, a software infrastructure has been developed for lattice QCD that effectively utilize the capabilities of the INCITE facilities. These developments have enabled a new generation of Nuclear Physics calculations investigating the spectrum and structure of matter, such as the origin of mass and spin. This software infrastructure is described and recent results are reviewed.

  14. Strategies for chemical reaction searching in SciFinder

    PubMed

    Ridley

    2000-09-01

    The bibliographic, chemical structure, and chemical reaction databases produced by Chemical Abstracts Service allow a number of possibilities for chemical reaction searching. While these same databases may be searched through the STN network, many end-users find the intuitive software interface SciFinder simpler, but there still are issues to address. Searching may be performed through keywords, chemical structures, or chemical reactions, and the answers may vary with respect to precision and comprehension. Often combinations of search options may be needed to best solve the problem. Retrosynthetic analyses are easily performed in the chemical reaction database and can give unique insights into synthetic alternatives.

  15. Introduction to Structure Searching with SciFinder Scholar

    NASA Astrophysics Data System (ADS)

    Ridley, Damon D.

    2001-04-01

    CAS Registry Numbers provide a key to searching for chemical substances in CAS databases, and the challenge is to obtain the Registry Numbers for all the substances required. When the substances can be represented by structures, then one option is to find the Registry Numbers through structure searches. With SciFinder Scholar, the process of drawing and searching structures is intuitive; however, there are underlying issues and opportunities that need some explanation in courses on chemical information retrieval.We describe here our introductory course, which addresses the major ones.

  16. Psychometric evaluation of the Spanish version of the MPI-SCI

    PubMed Central

    Soler, MD; Cruz-Almeida, Y; Saurí, J; Widerström-Noga, EG

    2013-01-01

    Study design Postal surveys. Objectives To confirm the factor structure of the Spanish version of the MPI-SCI (MPI-SCI-S, Multidimensional Pain Inventory in the SCI population) and to test its internal consistency and construct validity in a Spanish population. Setting Guttmann Institute, Barcelona, Spain. Methods The MPI-SCI-S along with Spanish measures of pain intensity (Numerical Rating Scale), pain interference (Brief Pain Inventory), functional independence (Functional Independence Measure), depression (Beck Depression Inventory), locus of control (Multidimensional health Locus of Control), support (Functional Social Support Questionnaire (Duke-UNC)), psychological well-being (Psychological Global Well-Being Index) and demographic/injury characteristics were assessed in persons with spinal cord injury (SCI) and chronic pain (n = 126). Results Confirmatory factor analysis suggested an adequate factor structure for the MPI-SCI-S. The internal consistency of the MPI-SCI-S subscales ranged from acceptable (r = 0.66, Life Control) to excellent (r = 0.94, Life Interference). All MPI-SCI-S subscales showed adequate construct validity, with the exception of the Negative and Solicitous Responses subscales. Conclusions The Spanish version of the MPI-SCI is adequate for evaluating chronic pain impact following SCI in a Spanish-speaking population. Future studies should include additional measures of pain-related support in the Spanish-speaking SCI population. PMID:23608807

  17. SciFi - A large scintillating fibre tracker for LHCb

    NASA Astrophysics Data System (ADS)

    Kirn, Thomas

    2017-02-01

    The LHCb detector will be upgraded during the Long Shutdown 2 (LS2) of the LHC in order to cope with higher instantaneous luminosities and to read out the data at 40 MHz using a trigger-less read-out system. All front-end electronics will be replaced and several sub-detectors must be redesigned to cope with higher occupancy. The current tracking detectors downstream of the LHCb dipole magnet will be replaced by the Scintillating Fibre (SciFi) Tracker. Concept, design and operational parameters are driven by the challenging LHC environment including significant ionising and neutron radiation levels. Over a total active surface of 360 m2 the SciFi Tracker will use scintillating fibres (∅ = 0.25 mm) read out by state-of-the-art multi-channel Silicon Photomultipliers (SiPMs) arrays. A custom ASIC will be used to digitise the signals from the SiPMs. The project is now at the transition from R&D to series production. We will present the evolution of the design and the latest lab and test beam results.

  18. Measurements of CH4, N2O, CO, H2O and O3 in the middle atmosphere by the ATMOS experiment on Spacelab 3

    NASA Technical Reports Server (NTRS)

    Gunson, M. R.; Farmer, C. B.; Norton, R. H.; Zander, R.; Rinsland, C. P.; Shaw, J. H.; Gao, Bo-Cai

    1989-01-01

    The volume mixing ratios of five minor gases (CH4, N2O, CO, H2O, and O3) were retrieved through the middle atmosphere from the analysis of 0.01/cm resolution infrared solar occultation spectra recorded near 28 N and 48 S latitudes with the ATMOS (Atmospheric Trace Molecule Spectroscopy) instrument, flown on board Spacelab 3. The results, which constitute the first simultaneous observations of continuous profiles through the middle atmosphere for these gases, are in general agreement with reported measurements from ground, balloon and satellite-based instruments for the same seasons. In detail, the vertical profiles of these gases show the effects of the upper and middle atmospheric transport patterns dominant during the season of these observations. The profiles inferred at different longitudes around 28 N suggest a near-uniform zonal distribution of these gases. Although based on fewer observations, the sunrise occultation measurements point to a larger variability in the vertical distribution of these gases at 48 S.

  19. Continuous and discontinuous precipitation in Fe-1 at.%Cr-1 at.%Mo alloy upon nitriding; crystal structure and composition of ternary nitrides

    NASA Astrophysics Data System (ADS)

    Steiner, Tobias; Ramudu Meka, Sai; Rheingans, Bastian; Bischoff, Ewald; Waldenmaier, Thomas; Yeli, Guma; Martin, Tomas L.; Bagot, Paul A. J.; Moody, Michael P.; Mittemeijer, Eric J.

    2016-05-01

    The internal nitriding response of a ternary Fe-1 at.%Cr-1 at.%Mo alloy, which serves as a model alloy for many CrMo-based steels, was investigated. The nitrides developing upon nitriding were characterised by X-ray diffraction, scanning electron microscopy, electron probe microanalysis, transmission electron microscopy and atom probe tomography. The developed nitrides were shown to be (metastable) ternary mixed nitrides, which exhibit complex morphological, compositional and structural transformations as a function of nitriding time. Analogous to nitrided binary Fe-Cr and Fe-Mo alloys, in ternary Fe-Cr-Mo alloys initially continuous precipitation of fine, coherent, cubic, NaCl-type nitride platelets, here with the composition (Cr½,Mo½)N¾, occurs, with the broad faces of the platelets parallel to the {1 0 0}α-Fe lattice planes. These nitrides undergo a discontinuous precipitation reaction upon prolonged nitriding leading to the development of lamellae of a novel, hexagonal CrMoN2 nitride along {1 1 0}α-Fe lattice planes, and of spherical cubic, NaCl-type (Cr,Mo)Nx nitride particles within the ferrite lamellae. The observed structural and compositional changes of the ternary nitrides have been attributed to the thermodynamic and kinetic constraints for the internal precipitation of (misfitting) nitrides in the ferrite matrix.

  20. High resolution infrared spectroscopy from space: A preliminary report on the results of the Atmospheric Trace Molecule Spectroscopy (ATMOS) experiment on Spacelab 3

    NASA Technical Reports Server (NTRS)

    Farmer, Crofton B.; Raper, Odell F.

    1987-01-01

    The ATMOS (Atmospheric Trace Molecule Spectroscopy) experiment has the broad purpose of investigating the physical structure, chemistry, and dynamics of the upper atmosphere through the study of the distributions of the neutral minor and trace constituents and their seasonal and long-term variations. The technique used is high-resolution infrared absorption spectroscopy using the Sun as the radiation source, observing the changes in the transmission of the atmosphere as the line-of-sight from the Sun to the spacecraft penetrates the atmosphere close to the Earth's limb at sunrise and sunset. During these periods, interferograms are generated at the rate of one each second which yield, when transformed, high resolution spectra covering the 2.2 to 16 micron region of the infrared. Twenty such occultations were recorded during the Spacelab 3 flight, which have produced concentration profiles for a large number of minor and trace upper atmospheric species in both the Northern and Southern Hemispheres. Several of these species have not previously been observed in spectroscopic data. The data reduction and analysis procedures used following the flight are discussed; a number of examples of the spectra obtained are shown, and a bar graph of the species detected thus far in the analysis is given which shows the altitude ranges for which concentration profiles were retrieved.

  1. A Design Method for FES Bone Health Therapy in SCI

    PubMed Central

    Andrews, Brian; Shippen, James; Armengol, Monica; Gibbons, Robin; Holderbaum, William; Harwin, William

    2016-01-01

    FES assisted activities such as standing, walking, cycling and rowing induce forces within the leg bones and have been proposed to reduce osteoporosis in spinal cord injury (SCI). However, details of the applied mechanical stimulus for osteogenesis is often not reported. Typically, comparisons of bone density results are made after costly and time consuming clinical trials. These studies have produced inconsistent results and are subject to sample size variations. Here we propose a design process that may be used to predict the clinical outcome based on biomechanical simulation and mechano-biology. This method may allow candidate therapies to be optimized and quantitatively compared. To illustrate the approach we have used data obtained from a rower with complete paraplegia using the RowStim (III) system. PMID:28078075

  2. eSciMart: Web Platform for Scientific Software Marketplace

    NASA Astrophysics Data System (ADS)

    Kryukov, A. P.; Demichev, A. P.

    2016-10-01

    In this paper we suggest a design of a web marketplace where users of scientific application software and databases, presented in the form of web services, as well as their providers will have presence simultaneously. The model, which will be the basis for the web marketplace is close to the customer-to-customer (C2C) model, which has been successfully used, for example, on the auction sites such as eBay (ebay.com). Unlike the classical model of C2C the suggested marketplace focuses on application software in the form of web services, and standardization of API through which application software will be integrated into the web marketplace. A prototype of such a platform, entitled eSciMart, is currently being developed at SINP MSU.

  3. Stratospheric Observations of CH3D and HDO from ATMOS Infrared Solar Spectra: Enrichments of Deuterium in Methane and Implications for HD

    NASA Technical Reports Server (NTRS)

    Irion, F. W.; Moyer, E. J.; Gunson, M. R.; Rinsland, C. P.; Yung, Y. L.; Michelsen, H. A.; Salawitch, R. J.; Chang, A. Y.; Newchurch, M. J.; Abbas, M. M.; Abrams, M. C.; Zander, R.

    1996-01-01

    Stratospheric mixing ratios of CH3D from 100 mb to 17mb (approximately equals 15 to 28 km)and HDO from 100 mb to 10 mb (approximately equals 15 to 32 km) have been inferred from high resolution solar occultation infrared spectra from the Atmospheric Trace MOlecule Spectroscopy (ATMOS) Fourier-transform interferometer. The spectra, taken on board the Space Shuttle during the Spacelab 3 and ATLAS-1, -2, and -3 missions, extend in latitude from 70 deg S to 65 deg N. We find CH3D entering the stratosphere at an average mixing ratio of (9.9 +/- 0.8) x 10(exp -10) with a D/H ratio in methane (7.1 +/- 7.4)% less than that in Standard Mean Ocean Water (SMOW) (1 sigma combined precision and systematic error). In the mid to lower stratosphere, the average lifetime of CH3D is found to be (1.19 +/- 0.02) times that of CH4, resulting in an increasing D/H ratio in methane as air 'ages' and the methane mixing ratio decreases. We find an average of (1.0 +/- 0.1) molecules of stratospheric HDO are produced for each CH3D destroyed (1 sigma combined precision and systematic error), indicating that the rate of HDO production is approximately equal to the rate of CH3D destruction. Assuming negligible amounts of deuterium in species other than HDO, CH3D and HD, this limits the possible change in the stratospheric HD mixing ratio below about 10 mb to be +/- 0.1 molecules HD created per molecule CH3D destroyed.

  4. ScienceDirect through SciVerse: a new way to approach Elsevier.

    PubMed

    Bengtson, Jason

    2011-01-01

    SciVerse is the new combined portal from Elsevier that services their ScienceDirect collection, SciTopics, and their Scopus database. Using SciVerse to access ScienceDirect is the specific focus of this review. Along with advanced keyword searching and citation searching options, SciVerse also incorporates a very useful image search feature. The aim seems to be not only to create an interface that provides broad functionality on par with other database search tools that many searchers use regularly but also to create an open platform that could be changed to respond effectively to the needs of customers.

  5. Methodology for the development and calibration of the SCI-QOL item banks

    PubMed Central

    Tulsky, David S.; Kisala, Pamela A.; Victorson, David; Choi, Seung W.; Gershon, Richard; Heinemann, Allen W.; Cella, David

    2015-01-01

    Objective To develop a comprehensive, psychometrically sound, and conceptually grounded patient reported outcomes (PRO) measurement system for individuals with spinal cord injury (SCI). Methods Individual interviews (n = 44) and focus groups (n = 65 individuals with SCI and n = 42 SCI clinicians) were used to select key domains for inclusion and to develop PRO items. Verbatim items from other cutting-edge measurement systems (i.e. PROMIS, Neuro-QOL) were included to facilitate linkage and cross-population comparison. Items were field tested in a large sample of individuals with traumatic SCI (n = 877). Dimensionality was assessed with confirmatory factor analysis. Local item dependence and differential item functioning were assessed, and items were calibrated using the item response theory (IRT) graded response model. Finally, computer adaptive tests (CATs) and short forms were administered in a new sample (n = 245) to assess test-retest reliability and stability. Participants and Procedures A calibration sample of 877 individuals with traumatic SCI across five SCI Model Systems sites and one Department of Veterans Affairs medical center completed SCI-QOL items in interview format. Results We developed 14 unidimensional calibrated item banks and 3 calibrated scales across physical, emotional, and social health domains. When combined with the five Spinal Cord Injury – Functional Index physical function banks, the final SCI-QOL system consists of 22 IRT-calibrated item banks/scales. Item banks may be administered as CATs or short forms. Scales may be administered in a fixed-length format only. Conclusions The SCI-QOL measurement system provides SCI researchers and clinicians with a comprehensive, relevant and psychometrically robust system for measurement of physical-medical, physical-functional, emotional, and social outcomes. All SCI-QOL instruments are freely available on Assessment CenterSM. PMID:26010963

  6. "Sci-Tech - Couldn't be without it !"

    NASA Astrophysics Data System (ADS)

    2002-03-01

    Launch of a Major European Outreach Programme Seven of Europe's leading Research Organizations [1] launch joint outreach programme for the European Science and Technology Week at the Technopolis Museum in Brussels on 22 March. Their aim is to show Europeans how today's society couldn't be without fundamental research . Could you imagine life without mobile phones, cars, CD players, TV, refrigerators, computers, the internet and the World Wide Web, antibiotics, vitamins, anaesthetics, vaccination, heating, pampers, nylon stockings, glue, bar codes, metal detectors, contact lenses, modems, laser printers, digital cameras, gameboys, play stations...? Technology is everywhere and used by everyone in today's society, but how many Europeans suspect that without studies on the structure of the atom, lasers would not exist, and neither would CD players? Most do not realise that most things they couldn't be without have required years of fundamental research . To fill this knowledge gap, the leading Research Organizations in Europe [1], with the support of the research directorate of the European Commission, have joined forces to inform Europeans how technology couldn't be without science, and how science can no longer progress without technology. The project is called...... Sci-Tech - Couldn't be without it! Sci-Tech - Couldn't be without it! invites Europeans to vote online in a survey to identify the top ten technologies they can't live without. It will show them through a dynamic and entertaining Web space where these top technologies really come from, and it will reveal their intimate links with research. Teaching kits will be developed to explain to students how their favourite gadgets actually work, and how a career in science can contribute to inventions that future generations couldn't be without. The results of the survey will be presented as a series of quiz shows live on the Internet during the Science Week, from 4 to 10 November. Sci-tech - Couldn't be without

  7. rOpenSci - open tools for open science

    NASA Astrophysics Data System (ADS)

    Ram, K.

    2013-12-01

    Solving many of the basic and applied challenges in ecology and evolution requires access to large amounts of data, often spanning long spatial and temporal scales. The long-established model where researchers collect and analyze their own data will soon be replaced by one where disparate datasets are brought to bear on both basic and applied problems. As science becomes more data-driven, it faces a whole new set of challenges. Researchers will not only have to maintain expertise in their domains but also learn new skills to curate, retrieve, and analyze these newly available data. In order to fully realize the potential of data-driven science and allow researchers to draw insights from these vast data stores, we need to address challenges associated with all aspects of the research life cycle. To foster and support a new generation of data-driven science, my colleagues and I founded a project called rOpenSci (http://ropensci.org). The project is an integrated effort to build tools and training using Ecology and Evolution as a model community. In this talk I will outline several of the barriers that need to be overcome including better incentive mechanisms for data, training gaps, and lowering technical barriers.

  8. SciDAC-Center for Plasma Edge Simulation

    SciTech Connect

    Chang, Choong Seock

    2012-06-04

    The SciDAC ProtoFSP Center for Plasma Edge Simulation (CPES) [http://www.cims.nyu.edu/cpes/] was awarded to New York University, Courant Institute of Mathematical Sciences in FY 2006. C.S. Chang was the institutional and national project PI. It's mission was 1) to build kinetic simulation code applicable to tokamak edge region including magnetic divertor geometry, 2) to build a computer science framework which can integrate the kinetic code with MHD/fluid codes in multiscale, 3) to conduct scientific research using the developed tools. CPES has built two such edge kinetic codes XGC0 and XGC1, which are still the only working kinetic edge plasma codes capable of including the diverted magnetic field geometry. CPES has also built the code coupling framework EFFIS (End-to-end Framework for Fusion Integrated Simulation), which incubated and used the Adios (www.olcf.ornl.gov/center-projects/adios/) and eSiMon (http://www.olcf.ornl.gov/center-projects/esimmon/) technologies, together with the Kepler technology.

  9. STARtorialist: Astronomy Outreach via Fashion, Sci-Fi, & Pop Culture

    NASA Astrophysics Data System (ADS)

    Rice, Emily L.; Ash, Summer

    2015-01-01

    Astronomical images in the public domain have increasingly been used as inspiration and patterns for clothing, accessories, and home decor. These 'AstroFashion' items are as diverse as DIY projects, handmade and boutique products, mass-produced commercial items, and haute couture. STARtorialist is a Tumblr-based blog that curates the proliferation of these products with the goal of celebrating the beauty of the universe and highlighting the science behind the images. The blog also includes sci-fi, space, and science-related aspects of popular culture. Each post features images and descriptions of the products, and often where/how we found them and/or the people wearing them, with links to the original astronomical images or other relevant science content. The popularity of each post is evident in the number of 'notes', including 'faves' (personal bookmarks) and 'reblogs' (shares with other users). Since launching the blog in December 2013, with an average of one post per day, we've attracted hundreds of followers on Tumblr and Twitter and thousands of notes on Tumblr. We will present our most popular posts and recommend how education, outreach, and press offices can add Tumblr to their social media repertoire.

  10. Particles in Action. Study Guide. Unit C2. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide is a four-part unit…

  11. Close Encounters of the Best Kind: The Latest Sci-Fi

    ERIC Educational Resources Information Center

    Kunzel, Bonnie

    2008-01-01

    Not only is science fiction alive and well--it's flourishing. From the big screen (howdy, Wall-E) to the big books (like Suzanne Collins's The Hunger Games, which has attracted loads of prepublication praise), 2008 has been a great year for sci-fi. Publishers have released truckloads of new sci-fi titles this year, but what's particularly…

  12. The Adequacy of the Science Citation Index (SCI) as an Indicator of International Scientific Activity.

    ERIC Educational Resources Information Center

    Carpenter, Mark P.; Narin, Francis

    1981-01-01

    Presents the results of a study of Science Citation Index (SCI) as a source for developing indicators of international scientific activity. Journal counts based on SCI and British Library Lending Division (BLLD) cataloging records are compared and reference patterns in key journals are described. Eleven references are listed. (JL)

  13. What is Matter? Study Guide. Unit C1. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide is a two-part unit…

  14. Detection of Abnormal Muscle Activations during Walking Following Spinal Cord Injury (SCI)

    ERIC Educational Resources Information Center

    Wang, Ping; Low, K. H.; McGregor, Alison H.; Tow, Adela

    2013-01-01

    In order to identify optimal rehabilitation strategies for spinal cord injury (SCI) participants, assessment of impaired walking is required to detect, monitor and quantify movement disorders. In the proposed assessment, ten healthy and seven SCI participants were recruited to perform an over-ground walking test at slow walking speeds. SCI…

  15. What Makes Things Happen? Study Guide. Unit B. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Dube, Peter

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  16. Membrane Targeting and Insertion of the C-Tail Protein SciP.

    PubMed

    Pross, Eva; Soussoula, Lavinia; Seitl, Ines; Lupo, Domenico; Kuhn, Andreas

    2016-10-09

    C-tailed membrane proteins insert into the bilayer post-translationally because the hydrophobic anchor segment leaves the ribosome at the end of translation. Nevertheless, we find here evidence that the targeting of SciP to the membrane of Escherichia coli occurs co-translationally since signal elements in the N-terminal part of the SciP protein sequence are present. Two short hydrophobic sequences were identified that targeted a green fluorescent protein-SciP fusion protein to the membrane involving the signal recognition particle. After targeting, the membrane insertion of SciP is catalyzed by YidC independent of the SecYEG translocase. However, when the C-terminal tail of SciP was extended to 21 aa residues, we found that SecYEG becomes involved and makes its membrane insertion more efficient.

  17. First time experiences using SciPy for computer vision research

    SciTech Connect

    Eads, Damian R; Rosten, Edward J

    2008-01-01

    SciPy is an effective tool suite for prototyping new algorithms. We share some of our experiences using it for the first time to support our research in object detection. SciPy makes it easy to integrate C code, which is essential when algorithms operating on large data sets cannot be vectorized. Python's extensive support for operator overloading makes SciPy's syntax as succinct as its competitors, MATLAB. Octave. and R. The universality of Python. the language in which SciPy was written, gives the researcher access to a broader set of non-numerical libraries to support GUI development. interface with databases, manipulate graph structures, render 3D graphics, unpack binary files, etc. More profoundly, we found it easy to rework research code written with SciPy into a production application, deployable on numerous platforms.

  18. Data Sharing and Publication Using the SciDrive Service

    NASA Astrophysics Data System (ADS)

    Mishin, D.; Medvedev, D.; Szalay, A. S.; Plante, R.; Graham, M.

    2014-05-01

    Despite all the progress made during the last years in the field of cloud data storage, the problem of fast and reliable data storage for the scientific community still remains open. The SciDrive project meets the need for a free open-source scientific data publishing platform. Having the primary target audience of astronomers as the largest data producers, the platform however is not bound to any scientific domain and can be used by different communities. Our current installation provides a free and safe storage platform for scientists to publish their data and share it with the community with the simplicity of Dropbox. The system allows service providers to harvest from the files and derive their broader context in a fairly automated fashion. Collecting various scientific data files in a single location or multiple connected sites allows building an intelligent system of metadata extractors. Our system is aimed at simplifying the cataloging and processing of large file collections for the long tail of scientific data. We propose an extensible plugin architecture for automatic metadata extraction and storage. The current implementation targets some of the data formats commonly used by the astronomy communities, including FITS, ASCII and Excel tables, TIFF images, and YT simulations data archives. Along with generic metadata, format-specific metadata is also processed. For example, basic information about celestial objects is extracted from FITS files and TIFF images, if present. This approach makes the simple BLOB storage a smart system providing access to various data in its own representation, such as a database for files containing tables, or providing additional search and access features such as full-text search, image pyramids or thumbnails creation, simulation dataset id extractor for fast search. A 100TB implementation has just been put into production at Johns Hopkins University.

  19. Data publication and sharing using the SciDrive service

    NASA Astrophysics Data System (ADS)

    Mishin, Dmitry; Medvedev, D.; Szalay, A. S.; Plante, R. L.

    2014-01-01

    Despite the last years progress in scientific data storage, still remains the problem of public data storage and sharing system for relatively small scientific datasets. These are collections forming the “long tail” of power log datasets distribution. The aggregated size of the long tail data is comparable to the size of all data collections from large archives, and the value of data is significant. The SciDrive project's main goal is providing the scientific community with a place to reliably and freely store such data and provide access to it to broad scientific community. The primary target audience of the project is astoromy community, and it will be extended to other fields. We're aiming to create a simple way of publishing a dataset, which can be then shared with other people. Data owner controls the permissions to modify and access the data and can assign a group of users or open the access to everyone. The data contained in the dataset will be automaticaly recognized by a background process. Known data formats will be extracted according to the user's settings. Currently tabular data can be automatically extracted to the user's MyDB table where user can make SQL queries to the dataset and merge it with other public CasJobs resources. Other data formats can be processed using a set of plugins that upload the data or metadata to user-defined side services. The current implementation targets some of the data formats commonly used by the astronomy communities, including FITS, ASCII and Excel tables, TIFF images, and YT simulations data archives. Along with generic metadata, format-specific metadata is also processed. For example, basic information about celestial objects is extracted from FITS files and TIFF images, if present. A 100TB implementation has just been put into production at Johns Hopkins University. The system features public data storage REST service supporting VOSpace 2.0 and Dropbox protocols, HTML5 web portal, command-line client and Java

  20. Effects of Early Acute Care on Autonomic Outcomes in SCI: Bedside to Bench and Back

    DTIC Science & Technology

    2014-10-30

    spinal cord injury (SCI), but evidence-based protocols are needed. Optimal early treatment and management of SCI has not been established in clinical...and electronic medical records of SCI patients We have held meetings with the SFGH spinal cord injury clinicians and have established methods for...of  blood  pressure  in  the  rats  after   spinal  cord   injury  at  the  high  thoracic  level  using  the

  1. Sci-Hub: What Librarians Should Know and Do about Article Piracy.

    PubMed

    Hoy, Matthew B

    2017-01-01

    The high cost of journal articles has driven many researchers to turn to a new way of getting access: "pirate" article sites. Sci-Hub, the largest and best known of these sites, currently offers instant access to more than 58 million journal articles. Users attracted by the ease of use and breadth of the collection may not realize that these articles are often obtained using stolen credentials and downloading them may be illegal. This article will briefly describe Sci-Hub and how it works, the legal and ethical issues it raises, and the problems it may cause for librarians. Librarians should be aware of Sci-Hub and the ways it may change their patrons' expectations. They should also understand the risks Sci-Hub can pose to their patrons and their institutions.

  2. 76 FR 10395 - BreconRidge Manufacturing Solutions, Now Known as Sanmina-SCI Corporation, Division...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... Corporation, Division Optoelectronic and Microelectronic Design and Manufacturing, a Subsidiary of Sanmina-SCI Corporation, Including On- Site Leased Workers From Kelly Services, Penski, Inc., and Whitney Enterprises... Corporation, Division Optoelectronic and Microelectronic Design and Manufacturing, a subsidiary of...

  3. Complementary use of the SciSearch database for improved biomedical information searching.

    PubMed Central

    Brown, C M

    1998-01-01

    The use of at least two complementary online biomedical databases is generally considered critical for biomedical scientists seeking to keep fully abreast of recent research developments as well as to retrieve the highest number of relevant citations possible. Although the National Library of Medicine's MEDLINE is usually the database of choice, this paper illustrates the benefits of using another database, the Institute for Scientific Information's SciSearch, when conducting a biomedical information search. When a simple query about red wine consumption and coronary artery disease was posed simultaneously in both MEDLINE and SciSearch, a greater number of relevant citations were retrieved through SciSearch. This paper also provides suggestions for carrying out a comprehensive biomedical literature search in a rapid and efficient manner by using SciSearch in conjunction with MEDLINE. PMID:9549014

  4. SciServer Compute brings Analysis to Big Data in the Cloud

    NASA Astrophysics Data System (ADS)

    Raddick, Jordan; Medvedev, Dmitry; Lemson, Gerard; Souter, Barbara

    2016-06-01

    SciServer Compute uses Jupyter Notebooks running within server-side Docker containers attached to big data collections to bring advanced analysis to big data "in the cloud." SciServer Compute is a component in the SciServer Big-Data ecosystem under development at JHU, which will provide a stable, reproducible, sharable virtual research environment.SciServer builds on the popular CasJobs and SkyServer systems that made the Sloan Digital Sky Survey (SDSS) archive one of the most-used astronomical instruments. SciServer extends those systems with server-side computational capabilities and very large scratch storage space, and further extends their functions to a range of other scientific disciplines.Although big datasets like SDSS have revolutionized astronomy research, for further analysis, users are still restricted to downloading the selected data sets locally - but increasing data sizes make this local approach impractical. Instead, researchers need online tools that are co-located with data in a virtual research environment, enabling them to bring their analysis to the data.SciServer supports this using the popular Jupyter notebooks, which allow users to write their own Python and R scripts and execute them on the server with the data (extensions to Matlab and other languages are planned). We have written special-purpose libraries that enable querying the databases and other persistent datasets. Intermediate results can be stored in large scratch space (hundreds of TBs) and analyzed directly from within Python or R with state-of-the-art visualization and machine learning libraries. Users can store science-ready results in their permanent allocation on SciDrive, a Dropbox-like system for sharing and publishing files. Communication between the various components of the SciServer system is managed through SciServer‘s new Single Sign-on Portal.We have created a number of demos to illustrate the capabilities of SciServer Compute, including Python and R scripts

  5. Novel Target for Ameliorating Pain and Other Problems after SCI: Spontaneous Activity in Nociceptors

    DTIC Science & Technology

    2014-10-01

    Pain gests that interventions preferentially targeting nociceptive pri- mary afferent neurons, such as antagonists of Nav1.8 (Jarvis et al., 2007) or... pain afflicts a majority of SCI patients (Dijkers et al., 2009). This pain is typically divided into two major classes, nociceptive and neuropathic...Bryce et al., 2012). The largest prospective pain study of patients with traumatic SCI found that moderate-to-severe nociceptive and neuro- pathic pain

  6. SCI Survey to Determine Pressure Ulcer Vulnerability in the Outpatient Population

    DTIC Science & Technology

    2011-10-01

    include an analysis of osteomyelitis diagnosis and treatment with plans to submit a proposed algorithm to the SCI-QUERI‘ (SCI-Quality Enhancement...34, is there independent ability to % SERVICE CONNECTED BOWEL PRGM LOC # HRS PER TREATMENT BLADDER CONTINENT BLADDER MANAGEMENT INDEWELLING CATHETER...ANEMIA AUTONOMIC DYSREFLEXIA DIABETES1 DIABETES2 HETEROTOPIC OSSIFICATION HYPERTHYROID HYPOTHYROID OSTEOMYELITIS PAIN LEVEL 1-10 TOBACCO USE PAST

  7. FES-Rowing versus Zoledronic Acid to Improve Bone Health in SCI

    DTIC Science & Technology

    2013-10-01

    SCI, although the risk is high in this population of osteoporosis -related bone fracture. This study aims to learn if the severe osteoporosis in lower... Osteoporosis , FES-rowing, zoledronic acid, exercise, bone health 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a...Introduction Serious spinal cord injury (SCI) causes osteoporosis in the lower extremities, significantly increasing the risk of bone fracture in

  8. Mid-year Status of MESSENGER SciBox Science Planning and Commanding

    NASA Astrophysics Data System (ADS)

    Nguyen, L.; Choo, T. H.; Steele, R. J.; Lucks, M.; Nair, H.; Perry, M. E.; Anderson, B. J.; Berman, A. F.; Solomon, S. C.

    2011-12-01

    More than halfway into its primary orbital mission, MESSENGER has successfully exploited the SciBox planning and commanding system to automate science observation scheduling and command generation for its full instrument suite, as well as its radio-frequency communication and guidance and control systems. MESSENGER's SciBox software coordinates instrument observations to determine the optimal conflict-free science schedule for the entire orbital mission and generates weekly command sequences for submission to mission operations. SciBox maximizes science return by filling all available observing opportunities and fully utilizing onboard storage and downlink bandwidth. As of four months into its one-year orbital mission, MESSENGER SciBox had scheduled the acquisition and downlink of nearly 40,000 images and comparable data sets from the spacecraft's six other instruments. The flexibility of MESSENGER SciBox allows for rapid re-optimization of schedules in the event of unforeseen circumstances. It has also allowed the science and planning teams to analyze rapidly the effects of modifying operational parameters and adding new observations. Within two hours, the entire mission can be re-optimized, schedules and command sequences generated, and a full set of plots and reports produced. The effects on resource usage, observational coverage, and compliance with operational constraints may be quickly assessed. This rapid turnaround ensures that optimal schedules are produced regardless of circumstances. We present an overview of the MESSENGER SciBox design and its operation.

  9. Targeting Translational Successes through CANSORT-SCI: Using Pet Dogs To Identify Effective Treatments for Spinal Cord Injury.

    PubMed

    Moore, Sarah A; Granger, Nicolas; Olby, Natasha J; Spitzbarth, Ingo; Jeffery, Nick D; Tipold, Andrea; Nout-Lomas, Yvette S; da Costa, Ronaldo C; Stein, Veronika M; Noble-Haeusslein, Linda J; Blight, Andrew R; Grossman, Robert G; Basso, D Michele; Levine, Jonathan M

    2017-03-22

    Translation of therapeutic interventions for spinal cord injury (SCI) from laboratory to clinic has been historically challenging, highlighting the need for robust models of injury that more closely mirror the human condition. The high prevalence of acute, naturally occurring SCI in pet dogs provides a unique opportunity to evaluate expeditiously promising interventions in a population of animals that receive diagnoses and treatment clinically in a manner similar to persons with SCI, while adhering to National Institutes of Health guidelines for scientific rigor and transparent reporting. In addition, pet dogs with chronic paralysis are often maintained long-term by their owners, offering a similarly unique population for study of chronic SCI. Despite this, only a small number of studies have used the clinical dog model of SCI. The Canine Spinal Cord Injury Consortium (CANSORT-SCI) was recently established by a group of veterinarians and basic science researchers to promote the value of the canine clinical model of SCI. The CANSORT-SCI group held an inaugural meeting November 20 and 21, 2015 to evaluate opportunities and challenges to the use of pet dogs in SCI research. Key challenges identified included lack of familiarity with the model among nonveterinary scientists and questions about how and where in the translational process the canine clinical model would be most valuable. In light of these, we review the natural history, outcome, and available assessment tools associated with canine clinical SCI with emphasis on their relevance to human SCI and the translational process.

  10. Impact of Health Behaviors and Health Management on Employment After SCI: Psychological Health and Health Management

    PubMed Central

    Meade, Michelle A.; Krause, James S.

    2016-01-01

    Objective: The purpose of this study was to examine the relationship between employment and psychological health and health management as described by individuals with spinal cord injury (SCI) who were employed at least once following injury. Methods: A qualitative approach used 6 focus groups at 2 sites with 44 participants who were at least 10 years post SCI. All had been employed at some point since injury. Heterogeneous and homogeneous groups were delineated based on specific characteristics, such as education, gender, or race. Group sessions followed a semi-structured interview format with questions about personal, environmental, and policy related factors influencing employment following SCI. All group sessions were recorded, transcribed, and coded into conceptual categories to identify topics, themes, and patterns. Inferences were drawn about their meaning. NVivo 10 software using the constant comparative method was used for data analysis. Results: Narratives discussed the relationship between employment and psychological and emotional health and health management. Four themes were identified: (1) adjustment and dealing with emotional reactions, (2) gaining self-confidence, (3) preventing burnout, and (4) attitudes and perspectives. Most themes reflected issues that varied based on severity of injury as well as stage of employment. Conclusions: Individuals with SCI who are successful in working following injury must determine how to perform the behaviors necessary to manage their health and prevent emotional or physical complications. The emotional consequences of SCI must be recognized and addressed and specific behaviors enacted in order to optimize employment outcomes.

  11. Biomaterial scaffolds used for the regeneration of spinal cord injury (SCI).

    PubMed

    Kim, Moonhang; Park, So Ra; Choi, Byung Hyune

    2014-11-01

    This review presents a summary of various types of scaffold biomaterials used alone or together with therapeutic drugs and cells to regenerate spinal cord injury (SCI). The inhibitory environment and loss of axonal connections after SCI give rise to critical obstacles to regeneration of lost tissues and neuronal functions. Biomaterial scaffolds can provide a bridge to connect lost tissues, an adhesion site for implanted or host cells, and sustained release of therapeutic drugs in the injured spinal cord. In addition, they not only provide a structural platform, but can play active roles by inhibiting apoptosis of cells, inflammation and scar formation, and inducing neurogenesis, axonal growth and angiogenesis. Many synthetic and natural biomaterial scaffolds have been extensively investigated and tested in vitro and in animal SCI models for these purposes. We summarized the literature on the biomaterials commonly used for spinal cord regeneration in terms of historical backgrounds and current approaches.

  12. Charged-Current Neutral Pion production at SciBooNE

    SciTech Connect

    Catala-Perez, J.; /Valencia U., IFIC

    2009-10-01

    SciBooNE, located in the Booster Neutrino Beam at Fermilab, collected data from June 2007 to August 2008 to accurately measure muon neutrino and anti-neutrino cross sections on carbon below 1 GeV neutrino energy. SciBooNE is studying charged current interactions. Among them, neutral pion production interactions will be the focus of this poster. The experimental signature of neutrino-induced neutral pion production is constituted by two electromagnetic cascades initiated by the conversion of the {pi}{sup 0} decay photons, with an additional muon in the final state for CC processes. In this poster, I will present how we reconstruct and select charged-current muon neutrino interactions producing {pi}{sup 0}'s in SciBooNE.

  13. Implementing Connected Component Labeling as a User Defined Operator for SciDB

    NASA Technical Reports Server (NTRS)

    Oloso, Amidu; Kuo, Kwo-Sen; Clune, Thomas; Brown, Paul; Poliakov, Alex; Yu, Hongfeng

    2016-01-01

    We have implemented a flexible User Defined Operator (UDO) for labeling connected components of a binary mask expressed as an array in SciDB, a parallel distributed database management system based on the array data model. This UDO is able to process very large multidimensional arrays by exploiting SciDB's memory management mechanism that efficiently manipulates arrays whose memory requirements far exceed available physical memory. The UDO takes as primary inputs a binary mask array and a binary stencil array that specifies the connectivity of a given cell to its neighbors. The UDO returns an array of the same shape as the input mask array with each foreground cell containing the label of the component it belongs to. By default, dimensions are treated as non-periodic, but the UDO also accepts optional input parameters to specify periodicity in any of the array dimensions. The UDO requires four stages to completely label connected components. In the first stage, labels are computed for each subarray or chunk of the mask array in parallel across SciDB instances using the weighted quick union (WQU) with half-path compression algorithm. In the second stage, labels around chunk boundaries from the first stage are stored in a temporary SciDB array that is then replicated across all SciDB instances. Equivalences are resolved by again applying the WQU algorithm to these boundary labels. In the third stage, relabeling is done for each chunk using the resolved equivalences. In the fourth stage, the resolved labels, which so far are "flattened" coordinates of the original binary mask array, are renamed with sequential integers for legibility. The UDO is demonstrated on a 3-D mask of O(1011) elements, with O(108) foreground cells and O(106) connected components. The operator completes in 19 minutes using 84 SciDB instances.

  14. Bringing the SciBar detector to the booster neutrino beam

    SciTech Connect

    Aguilar-Arevalo, A.A.; Alcaraz, J.; Andringa, S.; Brice, S.J.; Brown, B.C.; Bugel, L.; Catala, J.; Cervera, A.; Conrad, J.M.; Couce, E.; Dore, U.; Espinal, X.; Finley, D.A.; Gomez-Cadenas, J.J.; Hayato, Y.; Hiraide, K.; Ishii, T.; Jover, G.; Kobilarcik, T.; Kurimoto, Y.; Kurosawa, Y.; /Columbia U. /Fermilab /KEK, Tsukuba /Barcelona, IFAE /Tokyo U., ICRR /Valencia U., IFIC /Kyoto U. /Los Alamos /Louisiana State U. /Stratton Mountain Sch. /Rome U. /INFN, Rome /Colorado U.

    2006-01-01

    This document presents the physics case for bringing SciBar, the fully active, finely segmented tracking detector at KEK, to the FNAL Booster Neutrino Beam (BNB) line. This unique opportunity arose with the termination of K2K beam operations in 2005. At that time, the SciBar detector became available for use in other neutrino beam lines, including the BNB, which has been providing neutrinos to the MiniBooNE experiment since late 2002. The physics that can be done with SciBar/BNB can be put into three categories, each involving several measurements. First are neutrino cross section measurements which are interesting in their own right, including analyses of multi-particle final states, with unprecedented statistics. Second are measurements of processes that represent the signal and primary background channels for the upcoming T2K experiment. Third are measurements which improve existing or planned MiniBooNE analyses and the understanding of the BNB, both in neutrino and antineutrino mode. For each of these proposed measurements, the SciBar/BNB combination presents a unique opportunity or will significantly improve upon current or near-future experiments for several reasons. First, the fine granularity of SciBar allows detailed reconstruction of final states not possible with the MiniBooNE detector. Additionally, the BNB neutrino energy spectrum is a close match to the expected T2K energy spectrum in a region where cross sections are expected to vary dramatically with energy. As a result, the SciBar/BNB combination will provide cross-section measurements in an energy range complementary to MINERvA and complete the knowledge of neutrino cross sections over the entire energy range of interest to the upcoming off-axis experiments.

  15. CitSci.org: A New Model for Managing, Documenting, and Sharing Citizen Science Data.

    PubMed

    Wang, Yiwei; Kaplan, Nicole; Newman, Greg; Scarpino, Russell

    2015-10-01

    Citizen science projects have the potential to advance science by increasing the volume and variety of data, as well as innovation. Yet this potential has not been fully realized, in part because citizen science data are typically not widely shared and reused. To address this and related challenges, we built CitSci.org (see www.citsci.org), a customizable platform that allows users to collect and generate diverse datasets. We hope that CitSci.org will ultimately increase discoverability and confidence in citizen science observations, encouraging scientists to use such data in their own scientific research.

  16. Final Report for DOE Project: Portal Web Services: Support of DOE SciDAC Collaboratories

    SciTech Connect

    Mary Thomas, PI; Geoffrey Fox, Co-PI; Gannon, D; Pierce, M; Moore, R; Schissel, D; Boisseau, J

    2007-10-01

    Grid portals provide the scientific community with familiar and simplified interfaces to the Grid and Grid services, and it is important to deploy grid portals onto the SciDAC grids and collaboratories. The goal of this project is the research, development and deployment of interoperable portal and web services that can be used on SciDAC National Collaboratory grids. This project has four primary task areas: development of portal systems; management of data collections; DOE science application integration; and development of web and grid services in support of the above activities.

  17. SciServer: An Online Collaborative Environment for Big Data in Research and Education

    NASA Astrophysics Data System (ADS)

    Raddick, Jordan; Souter, Barbara; Lemson, Gerard; Taghizadeh-Popp, Manuchehr

    2017-01-01

    For the past year, SciServer Compute (http://compute.sciserver.org) has offered access to big data resources running within server-side Docker containers. Compute has allowed thousands of researchers to bring advanced analysis to big datasets like the Sloan Digital Sky Survey and others, while keeping the analysis close to the data for better performance and easier read/write access. SciServer Compute is just one part of the SciServer system being developed at Johns Hopkins University, which provides an easy-to-use collaborative research environment for astronomy and many other sciences.SciServer enables these collaborative research strategies using Jupyter notebooks, in which users can write their own Python and R scripts and execute them on the same server as the data. We have written special-purpose libraries for querying, reading, and writing data. Intermediate results can be stored in large scratch space (hundreds of TBs) and analyzed directly from within Python or R with state-of-the-art visualization and machine learning libraries. Users can store science-ready results in their permanent allocation on SciDrive, a Dropbox-like system for sharing and publishing files.SciServer Compute’s virtual research environment has grown with the addition of task management and access control functions, allowing collaborators to share both data and analysis scripts securely across the world. These features also open up new possibilities for education, allowing instructors to share datasets with students and students to write analysis scripts to share with their instructors. We are leveraging these features into a new system called “SciServer Courseware,” which will allow instructors to share assignments with their students, allowing students to engage with big data in new ways.SciServer has also expanded to include more datasets beyond the Sloan Digital Sky Survey. A part of that growth has been the addition of the SkyQuery component, which allows for simple, fast

  18. GeoSciML version 3: A GML application for geologic information

    NASA Astrophysics Data System (ADS)

    International Union of Geological Sciences., I. C.; Richard, S. M.

    2011-12-01

    After 2 years of testing and development, XML schema for GeoSciML version 3 are now ready for application deployment. GeoSciML draws from many geoscience data modelling efforts to establish a common suite of feature types to represent information associated with geologic maps (materials, structures, and geologic units) and observations including structure data, samples, and chemical analyses. After extensive testing and use case analysis, in December 2008 the CGI Interoperability Working Group (IWG) released GeoSciML 2.0 as an application schema for basic geological information. GeoSciML 2.0 is in use to deliver geologic data by the OneGeology Europe portal, the Geological Survey of Canada Groundwater Information Network (wet GIN), and the Auscope Mineral Resources portal. GeoSciML to version 3.0 is updated to OGC Geography Markup Language v3.2, re-engineered patterns for association of element values with controlled vocabulary concepts, incorporation of ISO19156 Observation and Measurement constructs for representing numeric and categorical values and for representing analytical data, incorporation of EarthResourceML to represent mineral occurrences and mines, incorporation of the GeoTime model to represent GSSP and stratigraphic time scale, and refactoring of the GeoSciML namespace to follow emerging ISO practices for decoupling of dependencies between standardized namespaces. These changes will make it easier for data providers to link to standard vocabulary and registry services. The depth and breadth of GeoSciML remains largely unchanged, covering the representation of geologic units, earth materials and geologic structures. ISO19156 elements and patterns are used to represent sampling features such as boreholes and rock samples, as well as geochemical and geochronologic measurements. Geologic structures include shear displacement structures (brittle faults and ductile shears), contacts, folds, foliations, lineations and structures with no preferred

  19. Sleep-Disordered Breathing in Chronic SCI: A Randomized Controlled Trial of Treatment Impact on Cognition, Quality of Life, and Cardiovascular Disease

    DTIC Science & Technology

    2014-10-01

    AWARD NUMBER: W81XWH-13-1-0479 TITLE: Sleep-Disordered Breathing in Chronic SCI: A...5a. CONTRACT NUMBER Sleep-Disordered Breathing in Chronic SCI: A Randomized Controlled Trial of Treatment Impact on Cognition...SCI. In this prospective randomized controlled trial, we will objectively measure sleep disordered breathing (SDB) in chronic SCI patients using

  20. Scalable Earth-observation Analytics for Geoscientists: Spacetime Extensions to the Array Database SciDB

    NASA Astrophysics Data System (ADS)

    Appel, Marius; Lahn, Florian; Pebesma, Edzer; Buytaert, Wouter; Moulds, Simon

    2016-04-01

    Today's amount of freely available data requires scientists to spend large parts of their work on data management. This is especially true in environmental sciences when working with large remote sensing datasets, such as obtained from earth-observation satellites like the Sentinel fleet. Many frameworks like SpatialHadoop or Apache Spark address the scalability but target programmers rather than data analysts, and are not dedicated to imagery or array data. In this work, we use the open-source data management and analytics system SciDB to bring large earth-observation datasets closer to analysts. Its underlying data representation as multidimensional arrays fits naturally to earth-observation datasets, distributes storage and computational load over multiple instances by multidimensional chunking, and also enables efficient time-series based analyses, which is usually difficult using file- or tile-based approaches. Existing interfaces to R and Python furthermore allow for scalable analytics with relatively little learning effort. However, interfacing SciDB and file-based earth-observation datasets that come as tiled temporal snapshots requires a lot of manual bookkeeping during ingestion, and SciDB natively only supports loading data from CSV-like and custom binary formatted files, which currently limits its practical use in earth-observation analytics. To make it easier to work with large multi-temporal datasets in SciDB, we developed software tools that enrich SciDB with earth observation metadata and allow working with commonly used file formats: (i) the SciDB extension library scidb4geo simplifies working with spatiotemporal arrays by adding relevant metadata to the database and (ii) the Geospatial Data Abstraction Library (GDAL) driver implementation scidb4gdal allows to ingest and export remote sensing imagery from and to a large number of file formats. Using added metadata on temporal resolution and coverage, the GDAL driver supports time-based ingestion of

  1. [Analysis of the citation of the articles published in National Journal of Andrology by SCI periodicals from 2002 to 2008].

    PubMed

    Huang, Hai

    2009-03-01

    Science Citation Index (SCI) is one of the world's most important and influential information retrieval systems. Today Web of Science covers over 9000 international and regional journals and book series in every field of natural sciences, social sciences, and arts and humanities. More and more Chinese periodicals have been cited by SCI. This paper briefly introduces the SCI database and its selection process and analyzes the citation of the articles published in National Journal of Andrology (NJA) by SCI journals from 2002 to 2008, aiming to provide some information for the internationalization of NJA.

  2. What Makes Things Happen? Teacher's Guide. Unit B. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Dube, Peter

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  3. Particles in Action. Teacher's Guide. Unit C2. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  4. Purification and biochemical characterisation of human and murine stem cell inhibitors (SCI).

    PubMed

    Graham, G J; Freshney, M G; Donaldson, D; Pragnell, I B

    1992-01-01

    We have recently characterised an inhibitor of haemopoietic stem cell proliferation (SCI/MIP-1 alpha) and report here on its purification and initial biological and biochemical characterisation. The activity can be detected by direct addition to the CFU-A stem cell assay and this simple test for inhibitory activity has greatly facilitated the purification of the molecule. The purification involves a combination of Mono Q ion exchange chromatography, heparin-sepharose affinity chromatography and Blue Sepharose affinity chromatography. The purified stem cell inhibitor is an 8 kD peptide which is identical to the previously described peptide macrophage inflammatory protein 1 alpha. The peptide has a natural tendency to form large self-aggregates and appears, in physiological buffers, to have a native molecular weight of around 90 kD. SCI is a heat stable, protease sensitive protein which is half maximally active at between 10 and 25 pM in the CFU-A assay. The self-aggregates can be disrupted by dilute solutions of acetic acid and it appears that disruption increases the specific activity of SCI preparations. We also report the characterisation of the human homologue of the stem cell inhibitor (human SCI/MIP-1 alpha) which is 74% identical to murine MIP-1 alpha and which shares all the above features of the murine inhibitor.

  5. National Computational Infrastructure for Lattice Gauge Theory SciDAC-2 Closeout Report Indiana University Component

    SciTech Connect

    Gottlieb, Steven Arthur; DeTar, Carleton; Tousaint, Doug

    2014-07-24

    This is the closeout report for the Indiana University portion of the National Computational Infrastructure for Lattice Gauge Theory project supported by the United States Department of Energy under the SciDAC program. It includes information about activities at Indian University, the University of Arizona, and the University of Utah, as those three universities coordinated their activities.

  6. Novel Target for Ameliorating Pain and Other Problems after SCI: Spontaneous Activityin Nociceptors

    DTIC Science & Technology

    2015-10-01

    the function of a sodium ion channel, Nav1.8, that is selectively expressed in primary afferent neurons (especially nociceptors) ameliorate reflex...potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A, 104:8520–8525

  7. Cross section analyses in MiniBooNE and SciBooNE experiments

    SciTech Connect

    Katori, Teppei

    2015-05-15

    The MiniBooNE experiment (2002-2012) and the SciBooNE experiment (2007-2008) are modern high statistics neutrino experiments, and they developed many new ideas in neutrino cross section analyses. In this note, I discuss selected topics of these analyses.

  8. SciJourn is magic: construction of a science journalism community of practice

    NASA Astrophysics Data System (ADS)

    Nicholas, Celeste R.

    2016-01-01

    This article is the first to describe the discoursal construction of an adolescent community of practice (CoP) in a non-school setting. CoPs can provide optimal learning environments. The adolescent community centered around science journalism and positioned itself dichotomously in relationship to school literacy practices. The analysis focuses on recordings from a panel-style research interview from an early implementation of the Science Literacy Through Science Journalism (SciJourn) project. Researchers trained high school students participating in a youth development program to write science news articles. Students engaged in the authentic practices of professional science journalists, received feedback from a professional editor, and submitted articles for publication. I used a fine-grained critical discourse analysis of genre, discourse, and style to analyze student responses about differences between writing in SciJourn and in school. Students described themselves as agentic in SciJourn and passive in school, using an academic writing discourse of deficit to describe schooling experiences. They affiliated with and defined a SciJourn CoP, constructing positive journalistic identities therein. Educators are encouraged to develop similar CoPs. The discursive features presented may be used to monitor the development of communities of practice in a variety of settings.

  9. SCI Survey to Determine Pressure Ulcer Vulnerability in the Outpatient Population

    DTIC Science & Technology

    2012-10-01

    2009. Patients with or without pressure ulcers were included. Patients with SCI due to terminal disease, multiple sclerosis of amyotrophic lateral ... sclerosis were excluded. A data extraction tool was used to compile information known to impact the development of pressure ulcers in persons with

  10. SciEthics Interactive: Science and Ethics Learning in a Virtual Environment

    ERIC Educational Resources Information Center

    Nadolny, Larysa; Woolfrey, Joan; Pierlott, Matthew; Kahn, Seth

    2013-01-01

    Learning in immersive 3D environments allows students to collaborate, build, and interact with difficult course concepts. This case study examines the design and development of the TransGen Island within the SciEthics Interactive project, a National Science Foundation-funded, 3D virtual world emphasizing learning science content in the context of…

  11. Performance Engineering Research Institute SciDAC-2 Enabling Technologies Institute Final Report

    SciTech Connect

    Lucas, Robert

    2013-04-20

    Enhancing the performance of SciDAC applications on petascale systems had high priority within DOE SC at the start of the second phase of the SciDAC program, SciDAC-2, as it continues to do so today. Achieving expected levels of performance on high-end computing (HEC) systems is growing ever more challenging due to enormous scale, increasing architectural complexity, and increasing application complexity. To address these challenges, the University of Southern California?s Information Sciences Institute organized the Performance Engineering Research Institute (PERI). PERI implemented a unified, tripartite research plan encompassing: (1) performance modeling and prediction; (2) automatic performance tuning; and (3) performance engineering of high profile applications. Within PERI, USC?s primary research activity was automatic tuning (autotuning) of scientific software. This activity was spurred by the strong user preference for automatic tools and was based on previous successful activities such as ATLAS, which automatically tuned components of the LAPACK linear algebra library, and other recent work on autotuning domain-specific libraries. Our other major component was application engagement, to which we devoted approximately 30% of our effort to work directly with SciDAC-2 applications. This report is a summary of the overall results of the USC PERI effort.

  12. Evaluating soil organic C sequestration in the Cotton Belt with the soil conditioning index (SCI)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Simulation models that are sensitive to management, edaphic factors, and climate could provide insightful probes of how land owners and producers might be able to sequester soil organic C and engage in emerging carbon markets. We used the soil conditioning index (SCI) embedded in the RUSLE2 model t...

  13. SciTech Clubs for Girls. [Final report], September 1, 1991--April 30, 1994

    SciTech Connect

    Malamud, E.; Diaz, O.; Cox, J.

    1994-12-31

    The program of SciTech Clubs for Girls and its progress are described. This is a program that promotes the learning of science and mathematics by girls in the age range of 9 to 13 years through the process of building exhibits and learning from local professionals. A list of exhibits and a critique of the program are given.

  14. Microlithography and resist technology information at your fingertips via SciFinder

    NASA Astrophysics Data System (ADS)

    Konuk, Rengin; Macko, John R.; Staggenborg, Lisa

    1997-07-01

    Finding and retrieving the information you need about microlithography and resist technology in a timely fashion can make or break your competitive edge in today's business environment. Chemical Abstracts Service (CAS) provides the most complete and comprehensive database of the chemical literature in the CAplus, REGISTRY, and CASREACT files including 13 million document references, 15 million substance records and over 1.2 million reactions. This includes comprehensive coverage of positive and negative resist formulations and processing, photoacid generation, silylation, single and multilayer resist systems, photomasks, dry and wet etching, photolithography, electron-beam, ion-beam and x-ray lithography technologies and process control, optical tools, exposure systems, radiation sources and steppers. Journal articles, conference proceedings and patents related to microlithography and resist technology are analyzed and indexed by scientific information analysts with strong technical background in these areas. The full CAS database, which is updated weekly with new information, is now available at your desktop, via a convenient, user-friendly tool called 'SciFinder.' Author, subject and chemical substance searching is simplified by SciFinder's smart search features. Chemical substances can be searched by chemical structure, chemical name, CAS registry number or molecular formula. Drawing chemical structures in SciFinder is easy and does not require compliance with CA conventions. Built-in intelligence of SciFinder enables users to retrieve substances with multiple components, tautomeric forms and salts.

  15. The SciELO Open Access: A Gold Way from the South

    ERIC Educational Resources Information Center

    Packer, Abel L.

    2009-01-01

    Open access has long emphasized access to scholarly materials. However, open access can also mean access to the means of producing visible and recognized journals. This issue is particularly important in developing and emergent countries. The SciELO (Scientific Electronic Library On-line) project, first started in Brazil and, shortly afterward, in…

  16. SciSpark's SRDD : A Scientific Resilient Distributed Dataset for Multidimensional Data

    NASA Astrophysics Data System (ADS)

    Palamuttam, R. S.; Wilson, B. D.; Mogrovejo, R. M.; Whitehall, K. D.; Mattmann, C. A.; McGibbney, L. J.; Ramirez, P.

    2015-12-01

    Remote sensing data and climate model output are multi-dimensional arrays of massive sizes locked away in heterogeneous file formats (HDF5/4, NetCDF 3/4) and metadata models (HDF-EOS, CF) making it difficult to perform multi-stage, iterative science processing since each stage requires writing and reading data to and from disk. We have developed SciSpark, a robust Big Data framework, that extends ApacheTM Spark for scaling scientific computations. Apache Spark improves the map-reduce implementation in ApacheTM Hadoop for parallel computing on a cluster, by emphasizing in-memory computation, "spilling" to disk only as needed, and relying on lazy evaluation. Central to Spark is the Resilient Distributed Dataset (RDD), an in-memory distributed data structure that extends the functional paradigm provided by the Scala programming language. However, RDDs are ideal for tabular or unstructured data, and not for highly dimensional data. The SciSpark project introduces the Scientific Resilient Distributed Dataset (sRDD), a distributed-computing array structure which supports iterative scientific algorithms for multidimensional data. SciSpark processes data stored in NetCDF and HDF files by partitioning them across time or space and distributing the partitions among a cluster of compute nodes. We show usability and extensibility of SciSpark by implementing distributed algorithms for geospatial operations on large collections of multi-dimensional grids. In particular we address the problem of scaling an automated method for finding Mesoscale Convective Complexes. SciSpark provides a tensor interface to support the pluggability of different matrix libraries. We evaluate performance of the various matrix libraries in distributed pipelines, such as Nd4jTM and BreezeTM. We detail the architecture and design of SciSpark, our efforts to integrate climate science algorithms, parallel ingest and partitioning (sharding) of A-Train satellite observations from model grids. These

  17. SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies

    PubMed Central

    Scorneaux, Bernard; Angulo, David; Borroto-Esoda, Katyna; Ghannoum, Mahmoud; Peel, Michael

    2017-01-01

    ABSTRACT SCY-078 is an orally bioavailable ß-1,3-glucan synthesis inhibitor (GSI) and the first-in-class of structurally novel triterpene antifungals in clinical development for treating candidemia and invasive candidiasis. In vitro susceptibilities by broth microdilution, antifungal carryover, and time-kill dynamics were determined for three reference (ATCC) strains (Candida albicans 90028, Candida parapsilosis 90018, and Candida tropicalis 750), a quality-control (QC) strain (Candida krusei 6258), and four other strains (C. albicans MYA-2732, 64124, and 76485 and Candida glabrata 90030). Caspofungin (CASP), fluconazole (FLC), and voriconazole (VRC) were comparators. For time-kill experiments, SCY-078 and CASP were evaluated at 0.25, 1, 2, 4, 8, and 16 times the MIC80, and FLU and VRC were evaluated at 4× MIC80. The time to reach 50%, 90%, and 99.9% reduction in the number of CFUs from the starting inoculum was determined. Net change in the number of CFU per milliliter was used to determine 50% and 90% effective concentrations and maximum effect (EC50, EC90, and Emax, respectively). The SCY-078 MIC range was between 0.0625 and 1 μg/ml and generally similar to that of CASP. Antifungal carryover was not observed for SCY-078. SCY-078 was fungicidal against seven isolates at ≥4× MIC (kill of ≥3 log10) and achieved a 1.7-log10 reduction in CFU count/milliliter against C. albicans 90028. CASP behaved similarly against each isolate and achieved a 1.5-log10 reduction in the number of CFU/milliliter against C. albicans 90028. Reductions of 50% in CFU count/milliliter were achieved rapidly (1 to 2.8 h); fungicidal endpoints were reached at 12.1 to 21.8 h at ≥4× MIC. EC90 was reached at ∼5× MIC at each time point to 24 h. The EC50 and EC90 values were generally similar (8 to 24 h). Time-kill behavior of CASP was similar to that of SCY-078. FLC and VRC were fungistatic. Overall, SCY-078 has primarily fungicidal activity against Candida spp. and behaved

  18. SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies.

    PubMed

    Scorneaux, Bernard; Angulo, David; Borroto-Esoda, Katyna; Ghannoum, Mahmoud; Peel, Michael; Wring, Stephen

    2017-03-01

    SCY-078 is an orally bioavailable ß-1,3-glucan synthesis inhibitor (GSI) and the first-in-class of structurally novel triterpene antifungals in clinical development for treating candidemia and invasive candidiasis. In vitro susceptibilities by broth microdilution, antifungal carryover, and time-kill dynamics were determined for three reference (ATCC) strains (Candida albicans 90028, Candida parapsilosis 90018, and Candida tropicalis 750), a quality-control (QC) strain (Candida krusei 6258), and four other strains (C. albicans MYA-2732, 64124, and 76485 and Candida glabrata 90030). Caspofungin (CASP), fluconazole (FLC), and voriconazole (VRC) were comparators. For time-kill experiments, SCY-078 and CASP were evaluated at 0.25, 1, 2, 4, 8, and 16 times the MIC80, and FLU and VRC were evaluated at 4× MIC80 The time to reach 50%, 90%, and 99.9% reduction in the number of CFUs from the starting inoculum was determined. Net change in the number of CFU per milliliter was used to determine 50% and 90% effective concentrations and maximum effect (EC50, EC90, and Emax, respectively). The SCY-078 MIC range was between 0.0625 and 1 μg/ml and generally similar to that of CASP. Antifungal carryover was not observed for SCY-078. SCY-078 was fungicidal against seven isolates at ≥4× MIC (kill of ≥3 log10) and achieved a 1.7-log10 reduction in CFU count/milliliter against C. albicans 90028. CASP behaved similarly against each isolate and achieved a 1.5-log10 reduction in the number of CFU/milliliter against C. albicans 90028. Reductions of 50% in CFU count/milliliter were achieved rapidly (1 to 2.8 h); fungicidal endpoints were reached at 12.1 to 21.8 h at ≥4× MIC. EC90 was reached at ∼5× MIC at each time point to 24 h. The EC50 and EC90 values were generally similar (8 to 24 h). Time-kill behavior of CASP was similar to that of SCY-078. FLC and VRC were fungistatic. Overall, SCY-078 has primarily fungicidal activity against Candida spp. and behaved comparably to CASP.

  19. Understanding Quality of Life in Adults with Spinal Cord Injury Via SCI-Related Needs and Secondary Complications

    PubMed Central

    Noreau, Luc; Leblond, Jean; Dumont, Frédéric S.

    2014-01-01

    Background: Understanding the factors that can predict greater quality of life (QoL) is important for adults with spinal cord injury (SCI), given that they report lower levels of QoL than the general population. Objectives: To build a conceptual model linking SCI-related needs, secondary complications, and QoL in adults with SCI. Prior to testing the conceptual model, we aimed to develop and evaluate the factor structure for both SCI-related needs and secondary complications. Methods: Individuals with a traumatic SCI (N = 1,137) responded to an online survey measuring 13 SCI-related needs, 13 secondary complications, and the Life Satisfaction Questionnaire to assess QoL. The SCI-related needs and secondary complications were conceptualized into factors, tested with a confirmatory factor analysis, and subsequently evaluated in a structural equation model to predict QoL. Results: The confirmatory factor analysis supported a 2-factor model for SCI related needs, χ2(61, N = 1,137) = 250.40, P <.001, comparative fit index (CFI) = .93, root mean square error of approximation (RMSEA) = .05, standardized root mean square residual (SRMR) = .04, and for 11 of the 13 secondary complications, χ2(44, N = 1,137) = 305.67, P < .001, CFI = .91, RMSEA = .060, SRMR = .033. The final 2 secondary complications were kept as observed constructs. In the structural model, both vital and personal development unmet SCI-related needs (β = -.22 and -.20, P < .05, respectively) and the neuro-physiological systems factor (β = -.45, P < .05) were negatively related with QoL. Conclusions: Identifying unmet SCI-related needs of individuals with SCI and preventing or managing secondary complications are essential to their QoL. PMID:25477745

  20. Science Classroom Inquiry (SCI) Simulations: A Novel Method to Scaffold Science Learning

    PubMed Central

    Peffer, Melanie E.; Beckler, Matthew L.; Schunn, Christian; Renken, Maggie; Revak, Amanda

    2015-01-01

    Science education is progressively more focused on employing inquiry-based learning methods in the classroom and increasing scientific literacy among students. However, due to time and resource constraints, many classroom science activities and laboratory experiments focus on simple inquiry, with a step-by-step approach to reach predetermined outcomes. The science classroom inquiry (SCI) simulations were designed to give students real life, authentic science experiences within the confines of a typical classroom. The SCI simulations allow students to engage with a science problem in a meaningful, inquiry-based manner. Three discrete SCI simulations were created as website applications for use with middle school and high school students. For each simulation, students were tasked with solving a scientific problem through investigation and hypothesis testing. After completion of the simulation, 67% of students reported a change in how they perceived authentic science practices, specifically related to the complex and dynamic nature of scientific research and how scientists approach problems. Moreover, 80% of the students who did not report a change in how they viewed the practice of science indicated that the simulation confirmed or strengthened their prior understanding. Additionally, we found a statistically significant positive correlation between students’ self-reported changes in understanding of authentic science practices and the degree to which each simulation benefitted learning. Since SCI simulations were effective in promoting both student learning and student understanding of authentic science practices with both middle and high school students, we propose that SCI simulations are a valuable and versatile technology that can be used to educate and inspire a wide range of science students on the real-world complexities inherent in scientific study. PMID:25786245

  1. Science classroom inquiry (SCI) simulations: a novel method to scaffold science learning.

    PubMed

    Peffer, Melanie E; Beckler, Matthew L; Schunn, Christian; Renken, Maggie; Revak, Amanda

    2015-01-01

    Science education is progressively more focused on employing inquiry-based learning methods in the classroom and increasing scientific literacy among students. However, due to time and resource constraints, many classroom science activities and laboratory experiments focus on simple inquiry, with a step-by-step approach to reach predetermined outcomes. The science classroom inquiry (SCI) simulations were designed to give students real life, authentic science experiences within the confines of a typical classroom. The SCI simulations allow students to engage with a science problem in a meaningful, inquiry-based manner. Three discrete SCI simulations were created as website applications for use with middle school and high school students. For each simulation, students were tasked with solving a scientific problem through investigation and hypothesis testing. After completion of the simulation, 67% of students reported a change in how they perceived authentic science practices, specifically related to the complex and dynamic nature of scientific research and how scientists approach problems. Moreover, 80% of the students who did not report a change in how they viewed the practice of science indicated that the simulation confirmed or strengthened their prior understanding. Additionally, we found a statistically significant positive correlation between students' self-reported changes in understanding of authentic science practices and the degree to which each simulation benefitted learning. Since SCI simulations were effective in promoting both student learning and student understanding of authentic science practices with both middle and high school students, we propose that SCI simulations are a valuable and versatile technology that can be used to educate and inspire a wide range of science students on the real-world complexities inherent in scientific study.

  2. Atoms and Molecules. Study Guide. Unit 2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 3.

    ERIC Educational Resources Information Center

    Mandizha, George

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the third year of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide is a four-part unit…

  3. Using Electricity. Study Guide. Unit I2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Chidume, Kwashira

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  4. Understanding Electricity. Study Guide. Unit I1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Chidume, Kwashira

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  5. Ranking Business and Economics Journals in South America Using the Scientific Electronic Library Online (SciELO)

    ERIC Educational Resources Information Center

    Alexander, Jennifer K.; Pradenas, Lorena; Parada, Victor; Scherer, Robert F.

    2012-01-01

    Access to published research for knowledge creation and education in the administrative science disciplines in South America has been enhanced since the introduction of the Scientific Electronic Library Online (SciELO). Although SciELO has been available as an online journal indexing and publication service since 1998, there have been no…

  6. 32 CFR 147.32 - Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for âQâ access authorization: For someone who is not the... Guidelines for Temporary Access § 147.32 Temporary eligibility for access at the top secret and SCI...

  7. 32 CFR 147.32 - Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for âQâ access authorization: For someone who is not the... Guidelines for Temporary Access § 147.32 Temporary eligibility for access at the top secret and SCI...

  8. What Do You Know about Water? Study Guide. Unit D. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Dube, Peter

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide is a three-part unit…

  9. Life, Beginning and Growing. Study Guide. Unit E1. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide is a three-part unit…

  10. 32 CFR 147.32 - Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for âQâ access authorization: For someone who is not the... Guidelines for Temporary Access § 147.32 Temporary eligibility for access at the top secret and SCI...

  11. Our Planet Earth. Teacher's Guide. Unit F1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities,…

  12. Reproducing by Flowers and Seeds. Study Guide. Unit E2. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Zesaguli, Josie

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and environmental laboratories. This ZIM-SCI study guide consists of…

  13. Sense from Senses. Study Guide. Unit J. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Simango, Sam

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  14. Forces in Living Things. Study Guide. Unit H2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Hosking, Bunty; Zesaguli, Josie

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  15. Learning to be a Scientist. Study Guide. Unit A1. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide introduces students to…

  16. Living Things and Their Food. Study Guide. Unit G2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  17. Energy for Living. Study Guide. Unit G1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide includes activities and…

  18. Forces in Action. Study Guide. Unit H1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Dube, Peter

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This ZIM-SCI study guide presents activities…

  19. Interaction of polyethylene glycol (PEG) with the membrane-binding domains following spinal cord injury (SCI): introduction of a mechanism for SCI repair.

    PubMed

    Rad, Iman; Khodayari, Kaveh; Hadi Alijanvand, Saeid; Mobasheri, Hamid

    2015-01-01

    Lipid-binding domains regulate positioning of the membrane proteins via specific interactions with phospholipid's head groups. Spinal cord injury (SCI) diminishes the integrity of neural fiber membranes at nanoscopic level. In cases that the ruptured zone size is beyond the natural resealing ability, there is a need for reinforcing factors such as polymers (e.g. Polyethylene glycol) to patch the dismantled axoplasm. Certain conserved sequential and structural patterns of interacting residues specifically bind to PEGs. It is also found that PEG600, PEG400 and PEG200 share the strongest interaction with the lipid-binding domains even more successful than phospholipid head groups. The alpha helix structure composed of hydrophobic, neutral and acidic residues prepares an opportunity for PEG400 to play an amphipathic role in the interaction with injured membrane. This in-silico study introduces a mechanism for PEG restorative ability at the molecular level. It is believed that PEG400 interrelates the injured membrane to their underneath axoplasm while retaining the integrity of ruptured membrane via interaction with ENTH domains of membrane proteins. This privilege of PEG400 in treating injured membrane must be considered in designing of polymeric biomaterials that are introduced for SCI repair.

  20. GENESIS SciFlo: Enabling Multi-Instrument Atmospheric Science Using Grid Workflows

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Tang, B.; Manipon, G.; Yunck, T.; Fetzer, E.; Braverman, A.; Dobinson, E.

    2004-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of web services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations will include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-strato-sphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we are developing a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo is a system for Scientific Knowledge Creation on the Grid using a Semantically-Enabled Dataflow Execution Environment. SciFlo leverages Simple Object Access Protocol (SOAP) Web Services and the Grid Computing standards (Globus Alliance toolkits), and enables scientists to do multi-instrument Earth Science by assembling reusable web services and executable operators into a distributed computing flow (operator tree). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. The scientist injects a distributed computation into the Grid by simply filling out

  1. GeoSciGraph: An Ontological Framework for EarthCube Semantic Infrastructure

    NASA Astrophysics Data System (ADS)

    Gupta, A.; Schachne, A.; Condit, C.; Valentine, D.; Richard, S.; Zaslavsky, I.

    2015-12-01

    The CINERGI (Community Inventory of EarthCube Resources for Geosciences Interoperability) project compiles an inventory of a wide variety of earth science resources including documents, catalogs, vocabularies, data models, data services, process models, information repositories, domain-specific ontologies etc. developed by research groups and data practitioners. We have developed a multidisciplinary semantic framework called GeoSciGraph semantic ingration of earth science resources. An integrated ontology is constructed with Basic Formal Ontology (BFO) as its upper ontology and currently ingests multiple component ontologies including the SWEET ontology, GeoSciML's lithology ontology, Tematres controlled vocabulary server, GeoNames, GCMD vocabularies on equipment, platforms and institutions, software ontology, CUAHSI hydrology vocabulary, the environmental ontology (ENVO) and several more. These ontologies are connected through bridging axioms; GeoSciGraph identifies lexically close terms and creates equivalence class or subclass relationships between them after human verification. GeoSciGraph allows a community to create community-specific customizations of the integrated ontology. GeoSciGraph uses the Neo4J,a graph database that can hold several billion concepts and relationships. GeoSciGraph provides a number of REST services that can be called by other software modules like the CINERGI information augmentation pipeline. 1) Vocabulary services are used to find exact and approximate terms, term categories (community-provided clusters of terms e.g., measurement-related terms or environmental material related terms), synonyms, term definitions and annotations. 2) Lexical services are used for text parsing to find entities, which can then be included into the ontology by a domain expert. 3) Graph services provide the ability to perform traversal centric operations e.g., finding paths and neighborhoods which can be used to perform ontological operations like

  2. SCiP at 35: an idiosyncratic history of the society for computers in psychology.

    PubMed

    Wolfe, Christopher R

    2006-05-01

    SCiP history may be divided into three eras: the Paleozoic (1971-1982), the Mesozoic (1982-1994), and the Cenozoic (1994-present). Following a list of Secretary-Treasurers, a list of all SCiP Presidents is provided in Table 1. Next I present personal highlights, including the first symposium on psychology and the World-Wide Web; David Rumelhart's mathematical explanation of connectionism; and Stevan Hamad's discussion of "freeing" the journal literature. I observe that a small conference is becoming more intimate and that much of our mission involves figuring out how to conduct high-quality scientific research with consumer-grade electronics. I argue that we are an increasingly international organization, that graduate students are welcome, and that we should become more inclusive in the areas of gender and ethnicity and should make membership more meaningful I conclude by looking ahead and attempting to predict the future.

  3. Simulations with SCI as a data carrier in data acquisition systems

    SciTech Connect

    Kristiansen, E.H. Univ. of Oslo . Dept. of Physics); Bothner, J.W.; Hulaas, T.I.; Skaali, T.B. ); Rongved, E. )

    1994-02-01

    Detailed simulations of processor networks based on the Scalable Coherent Interface (SCI) show that SCI is suitable as data carrier in data acquisition systems where the total bandwidth need is in the multi GBytes/s range and a low latency is required. The objective of these simulations was to find topologies with low latency and high bandwidth, but also with the cost of implementation in mind. A ring-to-ring bridge has been used as the building element for the networks. The simulations have been performed on regular k-ary n-cubes type topologies from a few tens of nodes and up to about 500 nodes under different load conditions. Among the parameters which has been manipulated in the simulations are the number of nodes, topology structure, number of outstanding requests and load in the system.

  4. Assembling Large, Multi-Sensor Climate Datasets Using the SciFlo Grid Workflow System

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Manipon, G.; Xing, Z.; Fetzer, E.

    2008-12-01

    NASA's Earth Observing System (EOS) is the world's most ambitious facility for studying global climate change. The mandate now is to combine measurements from the instruments on the A-Train platforms (AIRS, AMSR-E, MODIS, MISR, MLS, and CloudSat) and other Earth probes to enable large-scale studies of climate change over periods of years to decades. However, moving from predominantly single-instrument studies to a multi-sensor, measurement-based model for long-duration analysis of important climate variables presents serious challenges for large-scale data mining and data fusion. For example, one might want to compare temperature and water vapor retrievals from one instrument (AIRS) to another instrument (MODIS), and to a model (ECMWF), stratify the comparisons using a classification of the cloud scenes from CloudSat, and repeat the entire analysis over years of AIRS data. To perform such an analysis, one must discover & access multiple datasets from remote sites, find the space/time matchups between instruments swaths and model grids, understand the quality flags and uncertainties for retrieved physical variables, and assemble merged datasets for further scientific and statistical analysis. To meet these large-scale challenges, we are utilizing a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data query, access, subsetting, co-registration, mining, fusion, and advanced statistical analysis. SciFlo is a semantically-enabled ("smart") Grid Workflow system that ties together a peer-to-peer network of computers into an efficient engine for distributed computation. The SciFlo workflow engine enables scientists to do multi-instrument Earth Science by assembling remotely-invokable Web Services (SOAP or http GET URLs), native executables, command-line scripts, and Python codes into a distributed computing flow. A scientist visually authors the graph of operation in the VizFlow GUI, or uses a

  5. Assembling Large, Multi-Sensor Climate Datasets Using the SciFlo Grid Workflow System

    NASA Astrophysics Data System (ADS)

    Wilson, B.; Manipon, G.; Xing, Z.; Fetzer, E.

    2009-04-01

    NASA's Earth Observing System (EOS) is an ambitious facility for studying global climate change. The mandate now is to combine measurements from the instruments on the "A-Train" platforms (AIRS, AMSR-E, MODIS, MISR, MLS, and CloudSat) and other Earth probes to enable large-scale studies of climate change over periods of years to decades. However, moving from predominantly single-instrument studies to a multi-sensor, measurement-based model for long-duration analysis of important climate variables presents serious challenges for large-scale data mining and data fusion. For example, one might want to compare temperature and water vapor retrievals from one instrument (AIRS) to another instrument (MODIS), and to a model (ECMWF), stratify the comparisons using a classification of the "cloud scenes" from CloudSat, and repeat the entire analysis over years of AIRS data. To perform such an analysis, one must discover & access multiple datasets from remote sites, find the space/time "matchups" between instruments swaths and model grids, understand the quality flags and uncertainties for retrieved physical variables, assemble merged datasets, and compute fused products for further scientific and statistical analysis. To meet these large-scale challenges, we are utilizing a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data query, access, subsetting, co-registration, mining, fusion, and advanced statistical analysis. SciFlo is a semantically-enabled ("smart") Grid Workflow system that ties together a peer-to-peer network of computers into an efficient engine for distributed computation. The SciFlo workflow engine enables scientists to do multi-instrument Earth Science by assembling remotely-invokable Web Services (SOAP or http GET URLs), native executables, command-line scripts, and Python codes into a distributed computing flow. A scientist visually authors the graph of operation in the Viz

  6. Psychosocial and Behavioral Factors Associated with Bowel and Bladder Management after SCI

    DTIC Science & Technology

    2013-10-01

    family in the Jersey Shore and we stopped in Hershey, Pennsylvania. We stopped there for the night and we were thinking we’d go tour the chocolate ... mood , going out into the community and taking care of bowel and bladder dysfunction. The study is asking persons with SCI (civilians and veterans) and...You will also complete a series of questionnaires about your mood , the quality of care you get, and you bowel and bladder program and any specific

  7. FES-Rowing versus Zoledronic Acid to Improve Bone Health in SCI

    DTIC Science & Technology

    2012-10-01

    loss or to induce new bone formation following SCI, although the risk is high in this population of osteoporosis -related bone fracture. This study...aims to learn if the severe osteoporosis in lower extremities caused by spinal cord injuries can be slowed or reversed with a combination of an... exercise that simulates weight-bearing and a bisphosphonate medication. 70 Individuals with T3-12 spinal cord injuries will be enrolled in a 12-month

  8. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  9. SciDAC Visualization and Analytics Center for EnablingTechnology

    SciTech Connect

    Bethel, E. Wes; Johnson, Chris; Joy, Ken; Ahern, Sean; Pascucci,Valerio; Childs, Hank; Cohen, Jonathan; Duchaineau, Mark; Hamann, Bernd; Hansen, Charles; Laney, Dan; Lindstrom, Peter; Meredith, Jeremy; Ostrouchov, George; Parker, Steven; Silva, Claudio; Sanderson, Allen; Tricoche, Xavier

    2006-11-28

    The SciDAC2 Visualization and Analytics Center for EnablingTechnologies (VACET) began operation on 10/1/2006. This document, dated11/27/2006, is the first version of the VACET project management plan. Itwas requested by and delivered to ASCR/DOE. It outlines the Center'saccomplishments in the first six weeks of operation along with broadobjectives for the upcoming future (12-24 months).

  10. Developing a Meaningful Life: Social Reintegration of Service-Members and Veterans with SCI

    DTIC Science & Technology

    2014-10-01

    military veteran who suffered a service-related traumatic SCI. Methods: An in-depth anthropological interview was used with Jake, a 28-year old marine...spinal cord injury. 9 Participants Seth Messinger, Principal Investigator Associate Professor of Anthropology Seth Messinger is responsible...Networks for Veterans with Spinal Cord Injury in Obtaining Employment. Annals of Anthropological Practice. 37,2:40-56 Fritz, H., Lysack, C

  11. Improvement in student science proficiency through InSciEd out.

    PubMed

    Pierret, Chris; Sonju, James D; Leicester, Jean E; Hoody, Maggie; LaBounty, Thomas J; Frimannsdottir, Katrin R; Ekker, Stephen C

    2012-12-01

    Integrated Science Education Outreach (InSciEd Out) is a collaboration formed between Mayo Clinic, Winona State University, and Rochester Public Schools (MN) with the shared vision of achieving excellence in science education. InSciEd Out employs an equitable partnership model between scientists, teachers, education researchers, and the community. Teams of teachers from all disciplines within a single school experience cutting-edge science using the zebrafish model system, as well as current pedagogical methods, during a summer internship at the Mayo Clinic. Within the internship, the teachers produce new curriculum that directly addresses opportunities for science education improvement at their own school. Zebrafish are introduced within the new curriculum to support a living model of the practice of science. Following partnership with the InSciEd Out program and 2 years of implementation in the classroom, teacher-interns from a K-8 public school reported access to local scientific technology and expertise they had not previously recognized. Teachers also reported improved integration of other disciplines into the scientific curriculum and a flow of concepts vertically from K through 8. Students more than doubled selection of an Honors science track in high school to nearly 90%. 98% of students who took the Minnesota Comprehensive Assessments in their 5(th) and 8(th) grade year (a span that includes 2 years of InSciEd Out) showed medium or high growth in science proficiency. These metrics indicate that cooperation between educators and scientists can result in positive change in student science proficiency and demonstrate that a higher expectation in science education can be achieved in US public schools.

  12. Improvement in Student Science Proficiency Through InSciEd Out

    PubMed Central

    Sonju, James D.; Leicester, Jean E.; Hoody, Maggie; LaBounty, Thomas J.; Frimannsdottir, Katrin R.; Ekker, Stephen C.

    2012-01-01

    Abstract Integrated Science Education Outreach (InSciEd Out) is a collaboration formed between Mayo Clinic, Winona State University, and Rochester Public Schools (MN) with the shared vision of achieving excellence in science education. InSciEd Out employs an equitable partnership model between scientists, teachers, education researchers, and the community. Teams of teachers from all disciplines within a single school experience cutting-edge science using the zebrafish model system, as well as current pedagogical methods, during a summer internship at the Mayo Clinic. Within the internship, the teachers produce new curriculum that directly addresses opportunities for science education improvement at their own school. Zebrafish are introduced within the new curriculum to support a living model of the practice of science. Following partnership with the InSciEd Out program and 2 years of implementation in the classroom, teacher-interns from a K–8 public school reported access to local scientific technology and expertise they had not previously recognized. Teachers also reported improved integration of other disciplines into the scientific curriculum and a flow of concepts vertically from K through 8. Students more than doubled selection of an Honors science track in high school to nearly 90%. 98% of students who took the Minnesota Comprehensive Assessments in their 5th and 8th grade year (a span that includes 2 years of InSciEd Out) showed medium or high growth in science proficiency. These metrics indicate that cooperation between educators and scientists can result in positive change in student science proficiency and demonstrate that a higher expectation in science education can be achieved in US public schools. PMID:23244687

  13. The Small Carry-on Impactor (SCI) and the Hayabusa2 Impact Experiment

    NASA Astrophysics Data System (ADS)

    Saiki, T.; Imamura, H.; Arakawa, M.; Wada, K.; Takagi, Y.; Hayakawa, M.; Shirai, K.; Yano, H.; Okamoto, C.

    2016-10-01

    Hayabusa2 is a sample return mission of JAXA launched on 3 December 2014. Hayabusa2 is the successor of Hayabusa, which returned samples from the asteroid Itokawa to the Earth. Although the design of Hayabusa2 follows that of Hayabusa, the former is equipped with some new components. The small carry-on impactor (SCI) is one of those components. The SCI is a compact kinetic impactor designed to remove the asteroid surface regolith locally and create an artificial crater. One of the most important scientific objectives of Hayabusa2 is to investigate the chemical and physical properties of the internal materials and structures of the target body, asteroid Ryugu. Hayabusa2 will attempt to observe the resultant crater with some scientific instruments and to get samples from around the crater. High kinetic energy is required to create a meaningful crater, however, the impact system design needs to fit within strict constraints. Complicated functions, such as a guidance and control system, are not permitted. A special type of shaped charge is used for the acceleration of the impactor of the SCI in order to make system simpler. Using this explosion technique makes it possible to accelerate the impactor very quickly and to hit the asteroid without a guidance system. However, the impact operation will be complicated because the explosive is very powerful and it scatters high-speed debris at the detonation. This paper describes an overview of the SCI system, the results of the development testing and an outline of the impact experiment of the Hayabusa2 mission.

  14. Obesity/Overweight in Persons With Early and Chronic SCI: A Randomized, Multicenter, Controlled Lifestyle Intervention

    DTIC Science & Technology

    2014-10-01

    modeled after the landmark Diabetes Prevention Program (DPP) on obesity and component disease risks. The TLI consists of a 6-month clinical program...clinical trial (RCT) conducted at 2 SCI rehabilitation research centers and a Veterans Affairs Medical Centers. The study is modeled after the Diabetes ...Prevention Program (DPP), an NIH-sponsored 27-center RCT that reported a sustained 7% body weight reduction in pre- diabetic individuals accompanied by

  15. Pressure Relief Behaviors and Weight Shifting Activities to Prevent Pressure Ulcers in Persons with SCI

    DTIC Science & Technology

    2015-10-01

    PRINCIPAL INVESTIGATOR: Stephen Sprigle, PhD, PT CONTRACTING ORGANIZATION: Georgia Tech Research Corporation Atlanta GA 30332-0001 REPORT DATE...AND ADDRESS(ES) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Georgia Tech Research Corporation 505 10th St NW Atlanta GA 30332-0001 9...activities in persons with SCI Submitted to and Approved by: - Georgia Tech , Shepherd Center, Kessler have each approved the protocol - HRPO

  16. SciDAC Center for Gyrokinetic Particle Simulation of Turbulent Transport in Burning Plasmas

    SciTech Connect

    Lin, Zhihong

    2013-12-18

    During the first year of the SciDAC gyrokinetic particle simulation (GPS) project, the GPS team (Zhihong Lin, Liu Chen, Yasutaro Nishimura, and Igor Holod) at the University of California, Irvine (UCI) studied the tokamak electron transport driven by electron temperature gradient (ETG) turbulence, and by trapped electron mode (TEM) turbulence and ion temperature gradient (ITG) turbulence with kinetic electron effects, extended our studies of ITG turbulence spreading to core-edge coupling. We have developed and optimized an elliptic solver using finite element method (FEM), which enables the implementation of advanced kinetic electron models (split-weight scheme and hybrid model) in the SciDAC GPS production code GTC. The GTC code has been ported and optimized on both scalar and vector parallel computer architectures, and is being transformed into objected-oriented style to facilitate collaborative code development. During this period, the UCI team members presented 11 invited talks at major national and international conferences, published 22 papers in peer-reviewed journals and 10 papers in conference proceedings. The UCI hosted the annual SciDAC Workshop on Plasma Turbulence sponsored by the GPS Center, 2005-2007. The workshop was attended by about fifties US and foreign researchers and financially sponsored several gradual students from MIT, Princeton University, Germany, Switzerland, and Finland. A new SciDAC postdoc, Igor Holod, has arrived at UCI to initiate global particle simulation of magnetohydrodynamics turbulence driven by energetic particle modes. The PI, Z. Lin, has been promoted to the Associate Professor with tenure at UCI.

  17. Supporting Research using Satellite Data: A Framework for Spatiotemporal Queries in SciDB

    NASA Astrophysics Data System (ADS)

    Ho, S. S.; Krcal, L.

    2015-12-01

    Natural phenomena such as haze, hurricane, and blizzard that evolve over time usually do not have well-defined boundaries. Their features may be captured by multiple satellites. To process and extract information from the large-scale satellite data, one needs a data-intensive architecture for distributed storage and computation resources. Such architecture allows end users such as scientists to effectively run their computation tasks with sharing computational resources and intermediate results, but without data replication. The satellite data is most conveniently represented using arrays, exploiting its multidimensional nature. For our investigation, we use the open-source distributed, array-based SciDB as a platform for our spatiotemporal framework. SciDB conforms with the data-intensive architecture, providing a highly effectively computational and data storage platform. Moreover, it provides standard extension points, i.e., user defined data types, operators and functions. Our current work focuses on more sophisticated indices including cartesian-coordinate indices, hierarchical triangular mesh and hybrid indices with data statistics and indexing. Furthermore, we introduce a spatiotemporal framework that allows us to generate and maintain indices according to given criteria and perform spatial and temporal operators and predicates. This framework overcomes weaknesses in SciDB where standard underlying array operations are less effective. We will demonstrate some examples (e.g., hurricane research using satellite data) of the functionalities in the proposed spatiotemporal framework.

  18. Comparing NetCDF and SciDB on managing and querying 5D hydrologic dataset

    NASA Astrophysics Data System (ADS)

    Liu, Haicheng; Xiao, Xiao

    2016-11-01

    Efficiently extracting information from high dimensional hydro-meteorological modelling datasets requires smart solutions. Traditional methods are mostly based on files, which can be edited and accessed handily. But they have problems of efficiency due to contiguous storage structure. Others propose databases as an alternative for advantages such as native functionalities for manipulating multidimensional (MD) arrays, smart caching strategy and scalability. In this research, NetCDF file based solutions and the multidimensional array database management system (DBMS) SciDB applying chunked storage structure are benchmarked to determine the best solution for storing and querying 5D large hydrologic modelling dataset. The effect of data storage configurations including chunk size, dimension order and compression on query performance is explored. Results indicate that dimension order to organize storage of 5D data has significant influence on query performance if chunk size is very large. But the effect becomes insignificant when chunk size is properly set. Compression of SciDB mostly has negative influence on query performance. Caching is an advantage but may be influenced by execution of different query processes. On the whole, NetCDF solution without compression is in general more efficient than the SciDB DBMS.

  19. [SciELO: A cooperative project for the dissemination of science].

    PubMed

    Bojo Canales, C; Fraga Medín, C; Hernández Villegas, S; Primo Peña, E

    2009-10-01

    The article describes the SciELO (Scientific Electronic Library Online) model for the electronic publication and dissemination of scientific journals, its origin and evolution, methodology, components, services and potential, and its implantation in Spain. It consists of thirteen participant countries with eight certified web portals, with another 5 under development and another two thematic ones. In February 2009 Scielo.org had 611 magazines and 195,789 articles of which 46% were about health sciences. Spain became a project member in 1999 and launched the SciELO web portal in 2001, as well as 4 magazines. It currently has 39 titles in the field of Health Sciences; one of which is the Revista Española de Sanidad Penitenciaria, which joined the project in 2007 and which currently has 6 issues from 2007 and 2008 available. This makes it one of the most important open access initiatives existing. The report concludes by stating that the SciELO model contributes to the development of research and science by offering an effective and efficient method of promoting and increasing the dissemination of scientific publications in Latin America.

  20. An Exploratory Analysis of the Potential Association Between SCI Secondary Health Conditions and Daily Activities

    PubMed Central

    Cobb, John; Dumont, Frédéric S.; Leblond, Jean; Park, So Eyun; Noonan, Vanessa K.

    2014-01-01

    Background: Secondary health conditions (SHCs) are common following traumatic spinal cord injury (tSCI) and are believed to influence a person’s ability to participate in daily activities (DAs). This association should be understood so that health care providers may target interventions with clarity and purpose to manage SHCs and facilitate DAs to maximal effect. Objective: To explore the association between SHCs and DAs expressed as the increased chance of not participating as much as wanted in a DA when an SHC is present. Methods: Community-dwelling persons with tSCI (n = 1,137) responded to the SCI Community Survey. The occurrence and frequency of 21 SHCs were determined. The extent of participation in 26 DAs was measured. The relative risk (RR) of not participating as much as wanted in a DA when a SHC is present was calculated. Results: When some SHC were present, the RR of not participating as much as wanted increased significantly (range, 15%-153%; P < .001). Certain SHCs (light-headedness/dizziness, fatigue, weight problems, constipation, shoulder problems) were associated with a greater chance of not participating in many DAs. No single SHC was associated with every DA and conversely not every DA was associated with an SHC. Conclusions: Maximizing participation in DAs requires minimizing SHCs in every instance. Understanding the association between SHCs and DAs may facilitate targeted care resulting in less severe SHCs, greater participation in DAs, and benefits to both the individual and society. PMID:25477741

  1. [Analysis on acupuncture literature in Science Citation Index (SCI) periodicals in 2007].

    PubMed

    Gao, Liang; Tian, Li-xin; Guo, Yi

    2009-06-01

    To grasp the international developing tendency of acupuncture research and provide some references for promoting acupuncture and moxibustion internationalization process, the articles about acupuncture in Science Citation Index (SCI) periodicals in 2007 were retrieved by adopting the retrieval tactics on line in combination with database searching. Results indicate that 257 articles about acupuncture had been retrived from the SCI Web databases. These articles were published in 125 journals respectively, most of which were Euramerican journals. Among these journals, the impact factor of the Journal of the American Medical Association (JAMA), 25. 547, is the highest one. It is shown that the impact factors of the SCI periodicals, in which acupuncture articles embodied are increased, the quality of these articles are improved obviously and the types of the articles are various in 2007, but there is obvious difference in the results of these studies due to the difference of experimental methods, the subjects of these experiments and acupuncture manipulations. Therefore, standardization of many problems arising from the researches on acupuncture is extremely imminent.

  2. Family dynamics and psychosocial functioning in children with SCI/D from Colombia, South America

    PubMed Central

    Nicolais, Christina J.; Perrin, Paul B.; Panyavin, Ivan; Nicholls, Elizabeth G.; Olivera Plaza, Silvia Leonor; Quintero, Lorena Medina; Arango-Lasprilla, Juan Carlos

    2016-01-01

    Objective The purpose of this study was to examine the connections between family dynamics and the psychosocial functioning of children with spinal cord injuries and disorders (SCI/D). Design Cross-sectional. Setting Participants were recruited from communities in Neiva, Colombia. Participants Thirty children with SCI/D and their primary caregiver participated. Children were between 8 and 17 years of age, and had sustained their injury at least six months prior to data collection. Interventions NA. Outcome measures Participating children completed measures assessing their own psychosocial functioning (Children's Depression Inventory, Revised Children's Manifest Anxiety Scale-2, Pediatric Quality of Life Inventory), and their primary caregiver completed measures of family dynamics (Family Adaptability and Cohesion Evaluation Scale- Fourth Edition, Family Communication Scale, Family Assessment Device- General Functioning, Family Satisfaction Scale, Relationship-Focused Coping Scale). Results A correlation matrix showed a number of significant bivariate correlations between child and family variables, and three multiple regressions showed that family satisfaction, empathy, and flexibility significantly explained 27% of the variance in child worry; family satisfaction and communication explained 18% of the variance in child social anxiety; and family cohesion and communication explained 23% of the variance in child emotional functioning. Conclusions These findings highlight the importance of rehabilitation professionals considering the association between family dynamics and the psychosocial functioning of children with SCI/D when working with this population. PMID:25582185

  3. GeoSciML v3.0 - a significant upgrade of the CGI-IUGS geoscience data model

    NASA Astrophysics Data System (ADS)

    Raymond, O.; Duclaux, G.; Boisvert, E.; Cipolloni, C.; Cox, S.; Laxton, J.; Letourneau, F.; Richard, S.; Ritchie, A.; Sen, M.; Serrano, J.-J.; Simons, B.; Vuollo, J.

    2012-04-01

    GeoSciML version 3.0 (http://www.geosciml.org), released in late 2011, is the latest version of the CGI-IUGS* Interoperability Working Group geoscience data interchange standard. The new version is a significant upgrade and refactoring of GeoSciML v2 which was released in 2008. GeoSciML v3 has already been adopted by several major international interoperability initiatives, including OneGeology, the EU INSPIRE program, and the US Geoscience Information Network, as their standard data exchange format for geoscience data. GeoSciML v3 makes use of recently upgraded versions of several Open Geospatial Consortium (OGC) and ISO data transfer standards, including GML v3.2, SWE Common v2.0, and Observations and Measurements v2 (ISO 19156). The GeoSciML v3 data model has been refactored from a single large application schema with many packages, into a number of smaller, but related, application schema modules with individual namespaces. This refactoring allows the use and future development of modules of GeoSciML (eg; GeologicUnit, GeologicStructure, GeologicAge, Borehole) in smaller, more manageable units. As a result of this refactoring and the integration with new OGC and ISO standards, GeoSciML v3 is not backwardly compatible with previous GeoSciML versions. The scope of GeoSciML has been extended in version 3.0 to include new models for geomorphological data (a Geomorphology application schema), and for geological specimens, geochronological interpretations, and metadata for geochemical and geochronological analyses (a LaboratoryAnalysis-Specimen application schema). In addition, there is better support for borehole data, and the PhysicalProperties model now supports a wider range of petrophysical measurements. The previously used CGI_Value data type has been superseded in favour of externally governed data types provided by OGC's SWE Common v2 and GML v3.2 data standards. The GeoSciML v3 release includes worked examples of best practice in delivering geochemical

  4. SciNews: Incorporating Science Current Events in 21st Century Classrooms

    NASA Astrophysics Data System (ADS)

    DiMaggio, E.

    2011-12-01

    Middle school students are instructed with the aid of textbooks, lectures, and activities to teach topics that satisfy state standards. However, teaching materials created to convey standard-aligned science concepts often leave students asking how the content relates to their lives and why they should be learning it. Conveying relevance is important for student learning and retention, especially in science where abstract concepts can often be incorrectly perceived as irrelevant. One way to create an educational link between classroom content and everyday life is through the use of scientific current events. Students read, hear, and watch media coverage of natural events (such as the 2011 earthquake and tsunami in Japan), but do not necessarily relate the scientific information from media sources to classroom studies. Taking advantage of these brief 'teachable moments'--when student interest is high--provides a valuable opportunity to make classroom-to-everyday life associations and to incorporate inquiry based learning. To address this need, I create pre-packaged current event materials for middle to high school teachers that align to state standards, and which are short, effective, and easy to implement in the classroom. Each lesson takes approximately 15-30 minutes to implement, allowing teachers time to facilitate brief but meaningful discussions. I assemble materials within approximately one week of the regional or global science event, consisting of short slide shows, maps, videos, pictures, and real-time data. I use a listserv to send biweekly emails to subscribed instructors containing the current event topic and a link to download the materials. All materials are hosted on the Arizona State University Education Outreach SciNews website (http://sese.asu.edu/teacher-resources) and are archived. Currently, 285 educators subscribe to the SciNews listserv, representing 36 states and 19 countries. In order to assess the effectiveness and usefulness of Sci

  5. The High-resolution Stereo Color Imager (HiSCI) on ExoMars Trace Gas Orbiter (TGO)

    NASA Astrophysics Data System (ADS)

    McEwen, A. S.; Thomas, N.; Bridges, J.; Byrne, S.; Cremonese, G.; Delamere, W.; Hansen, C.; Hauber, E.; Ivanov, A.; Kestay, L.; Kirk, R.; Mangold, N.; Markiewicz, W.; Massironi, M.; Mattson, S.; Okubo, C.; Wray, J.

    2011-10-01

    HiSCI has been chosen for the payload of the ExoMars Trace Gas Orbiter (TGO), a joint ESA/NASA mission scheduled to arrive at Mars in 2016 [1]. There are 3 major HiSCI partners: (1) the telescope assembly will be built in Switzerland overseen by the University of Bern; (2) the overall design, electronics, and integration will be by Ball Aerospace in Colorado; and (3) operations will be joint with MRO's High Resolution Imaging Science Experiment (HiRISE) [2] at the University of Arizona. HiSCI will acquire the best-ever colour and stereo images over significant areas of Mars.

  6. Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates.

    PubMed

    Lamoth, Frédéric; Alexander, Barbara D

    2015-07-01

    The limited armamentarium of active and oral antifungal drugs against emerging non-Aspergillus molds is of particular concern. Current antifungal agents and the new orally available beta-1,3-d-glucan synthase inhibitor SCY-078 were tested in vitro against 135 clinical non-Aspergillus mold isolates. Akin to echinocandins, SCY-078 showed no or poor activity against Mucoromycotina and Fusarium spp. However, SCY-078 was highly active against Paecilomyces variotii and was the only compound displaying some activity against notoriously panresistant Scedosporium prolificans.

  7. Publishing datasets with eSciDoc and panMetaDocs

    NASA Astrophysics Data System (ADS)

    Ulbricht, D.; Klump, J.; Bertelmann, R.

    2012-04-01

    Currently serveral research institutions worldwide undertake considerable efforts to have their scientific datasets published and to syndicate them to data portals as extensively described objects identified by a persistent identifier. This is done to foster the reuse of data, to make scientific work more transparent, and to create a citable entity that can be referenced unambigously in written publications. GFZ Potsdam established a publishing workflow for file based research datasets. Key software components are an eSciDoc infrastructure [1] and multiple instances of the data curation tool panMetaDocs [2]. The eSciDoc repository holds data objects and their associated metadata in container objects, called eSciDoc items. A key metadata element in this context is the publication status of the referenced data set. PanMetaDocs, which is based on PanMetaWorks [3], is a PHP based web application that allows to describe data with any XML-based metadata schema. The metadata fields can be filled with static or dynamic content to reduce the number of fields that require manual entries to a minimum and make use of contextual information in a project setting. Access rights can be applied to set visibility of datasets to other project members and allow collaboration on and notifying about datasets (RSS) and interaction with the internal messaging system, that was inherited from panMetaWorks. When a dataset is to be published, panMetaDocs allows to change the publication status of the eSciDoc item from status "private" to "submitted" and prepare the dataset for verification by an external reviewer. After quality checks, the item publication status can be changed to "published". This makes the data and metadata available through the internet worldwide. PanMetaDocs is developed as an eSciDoc application. It is an easy to use graphical user interface to eSciDoc items, their data and metadata. It is also an application supporting a DOI publication agent during the process of

  8. A Novel Approach for Effectively Treating SCI Pain, Improving Opioid Efficacy, and Preventing Opioid-Induced Constipation: Key Role of Toll-Like Receptor 4 (TLR4)

    DTIC Science & Technology

    2015-10-01

    pain ; however, morphine for 7 d post-SCI has little effect on chronic thermal nociceptive thresholds in this model. Establishing effects of post-SCI...AWARD NUMBER: W81XWH-13-1-0277 TITLE: A Novel Approach for Effectively Treating SCI Pain , Improving Opioid Efficacy, and Preventing Opioid...SCI Pain , Improving Opioid Efficacy, and Preventing Opioid-Induced Constipation: Key Role of Toll-Like Receptor 4 (TLR4) 5a. CONTRACT NUMBER 5b

  9. Collaborative Science Using Web Services and the SciFlo Grid Dataflow Engine

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Manipon, G.; Xing, Z.; Yunck, T.

    2006-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo leverages remote Web Services, called via Simple Object Access Protocol (SOAP) or REST (one-line) URLs, and the Grid Computing standards (WS-* &Globus Alliance toolkits), and enables scientists to do multi-instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client &server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. In particular, SciFlo exploits the wealth of datasets accessible by OpenGIS Consortium (OGC) Web Mapping Servers & Web Coverage Servers (WMS/WCS), and by Open Data

  10. The Fulldome Curriculum for the Spitz SciDome Digital Planetarium: Volume 2

    NASA Astrophysics Data System (ADS)

    Bradstreet, David H.; Sanders, S. J.; Huggins, S.

    2014-01-01

    The Spitz Fulldome Curriculum (FDC) for the SciDome digital planetarium ushered in a new and innovative way to present astronomical pedagogy via its use of the unique teaching attributes of the digital planetarium. In the case of the FDC, which uses the ubiquitous Starry Night planetarium software as its driving engine, these engaging and novel teaching techniques have also been made usable to desktop computers and flat-screen video projectors for classroom use. Volume 2 of the FDC introduces exciting new classes and mini-lessons to further enlighten and invigorate students as they struggle with often difficult three dimensional astronomical concepts. Additionally, other topics with related astronomical ties have been created to integrate history into planetarium presentations. One of the strongest advantages of the SciDome is its use of Starry Night as its astronomical engine. With it students can create their own astronomical configurations in the computer lab or at home, using the PC or Mac version. They can then simply load their creations onto the SciDome planetarium system and display them for their classmates on the dome. This poster will discuss and illustrate some of the new content that has been developed for Volume 2. Topics covered in Volume 2 include eclipses, plotting planet locations on a curtate orbit chart by observing their positions in the sky, time and timekeeping (including sidereal day, hour angles, sidereal time, LAST, LMST, time zones and the International Date Line), teaching to the Boy Scout Merit Badge requirements, plotting scale analemmas on the surface of planets and interpreting them, precession, astronomical events in revolutionary Boston, the Lincoln Almanac Trial, eclipsing binaries, lunar librations, a trip through the universe, watching the speed of light move in real time, stellar sizes and the Milky Way.

  11. Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI

    PubMed Central

    Dobkin, B; Apple, D.; Barbeau, H.; Basso, M.; Behrman, A.; Deforge, D.; Ditunno, J.; Dudley, G.; Elashoff, R.; Fugate, L.; Harkema, S.; Saulino, M.; Scott, M.

    2014-01-01

    Objective To compare the efficacy of step training with body weight support on a treadmill (BWSTT) with over-ground practice to the efficacy of a defined over-ground mobility therapy (CONT) in patients with incomplete spinal cord injury (SCI) admitted for inpatient rehabilitation. Methods A total of 146 subjects from six regional centers within 8 weeks of SCI were entered in a single-blinded, multicenter, randomized clinical trial (MRCT). Subjects were graded on the American Spinal Injury Association Impairment Scale (ASIA) as B, C, or D with levels from C5 to L3 and had a Functional Independence Measure for locomotion (FIM-L) score <4. They received 12 weeks of equal time of BWSTT or CONT. Primary outcomes were FIM-L for ASIA B and C subjects and walking speed for ASIA C and D subjects 6 months after SCI. Results No significant differences were found at entry between treatment groups or at 6 months for FIM-L (n = 108) or walking speed and distance (n = 72). In the upper motor neuron (UMN) subjects, 35% of ASIA B, 92% of ASIA C, and all ASIA D subjects walked independently. Velocities for UMN ASIA C and D subjects were not significantly different for BWSTT (1.1 ± 0.6 m/s, n = 30) and CONT (1.1 ± 0.7, n = 25) groups. Conclusions The physical therapy strategies of body weight support on a treadmill and defined overground mobility therapy did not produce different outcomes. This finding was partly due to the unexpectedly high percentage of American Spinal Injury Association C subjects who achieved functional walking speeds, irrespective of treatment. The results provide new insight into disability after incomplete spinal cord injury and affirm the importance of the multicenter, randomized clinical trial to test rehabilitation strategies. PMID:16505299

  12. Studying the History of the Intergalactic Medium with the SCI-HI Experiment

    NASA Astrophysics Data System (ADS)

    Voytek, Tabitha Christine

    The Cosmic Dawn (z ˜ 15 -- 35) is the period in the history of our universe when stars first began to form in small Dark Matter minihalos. Light from these first stars is too dim for telescopes to see, which means that the Cosmic Dawn has never been directly measured. However, the first stars impacted the gas, or intergalactic medium (IGM), around them. The impact of the first stars was heating and eventual ionization of the IGM. The process of heating and ionization creates a spectrum that varies over redshift, namely the spatially averaged brightness temperature spectrum of 21-cm light from the IGM. Measurement of this spectrum will give us a first glimpse of the Cosmic Dawn. The "Sonda Cosmologica de las Islas para la Deteccion de Hidrogeno Neutro" (SCIHI) experiment is a collaboration between Carnegie Mellon University (CMU) and Instituto Nacional de Astrofisica, Optica y Electronica (INAOE) in Mexico and was designed to make this measurement. The SCI-HI experiment is a small-scale system which travels with the team to remote locations for deployments. These remote locations are necessary to avoid radio frequency interference and other environmental impacts on the system. This thesis describes the development and deployment of the SCI-HI experiment. It starts with the original design and covers development of the system over time. Deployment location selection is then discussed, including the results of site evaluations. In addition, the thesis outlines the data analysis process used for the system and shows results from data collected during the June 2013 deployment of the experiment. Finally, the thesis describes plans for the future of the SCI-HI experiment, including deployment to South Africa in 2015.

  13. A Characterization Of The GNAT SciTech STAR Class 0.5m Prototype Telescope

    NASA Astrophysics Data System (ADS)

    Barentine, J. C.; Culver, R. B.

    2002-05-01

    In 1995 the Global Network of Automated Telescopes (GNAT) acquired an option to purchase a 0.5m "STAR" class telescope, manufactured by SciTech Corporation of Forresthill, CA, contingent upon its attainment of performance specifications published by SciTech. In spite of a concerted, and protracted effort, the telescope has not yet approached the manufacturer's specifications, and has proven largely unusable for its intended purpose. In light of the difficult history of commercial development of true automated telescopes (see Sinnott 1996 and Henry 1994) it is important to understand the current state of such commercial systems. We present results of a characterization of this telescope and recommendations for how to proceed in light of its failure to attain specifications. Principle failings of the telescope can be summarized as follows: 1) the mechanical structure was inadequately designed and built, yielding large and unacceptable pointing and tracking errors, 2) the autoguider system was never successfully implemented, limiting the system to very short integrations, 3) the autofocus mechanism was never successfully implemented, resulting in periodic, unacceptable focus drifts during automatic operation, 4) the telescope control system as provided with the telescope did not work and ultimately had to be developed by an independent contractor recommended by GNAT and contracted through SciTech, and 5) the telescope optical system design did not adequately accommodate scattered light issues, yielding significant scattered light contributions to the images under certain conditions. Based on analyses of these issues, we present recommendations for improvements in this system. Support of this work has been provided by Colorado State University and GNAT. REFERENCES Sinnott, R.W. Sky And Telescope vol.91, no.6, p.38 (1996) Henry, G.W. IAPPP Communication No.57, Autumn 1994, p.57

  14. MicroRNA-146a Contributes to SCI Recovery via Regulating TRAF6 and IRAK1 Expression

    PubMed Central

    Wei, Jinsong; Zhou, Yulan; Yan, Shouquan

    2016-01-01

    MicroRNA-146a participates in spinal cord injury (SCI) recovery. Until recently, how miRNA-146a participates in SCI remained unclear. In this study, we tried to explore the roles of miRNA-146a in the recovery of SCI using a rat model. The expression of the probable target genes of miRNA-146a (including IRAK1 and TARF6) as well as proinflammation cytokines were measured until 7 days after surgery in the three groups (sham group, SCI group, and miRNA-146a antagomir injection group). Also, the animals' motivations were estimated using Basso Beattie Bresnahan (BBB) during the whole experiment. A luciferase assay was performed to demonstrate that miRNA-146a could directly target the mRNAs of IRAK1 and TRAF6. Our experiments indicate that miRNA-146a inhibits proinflammatory cytokine secretion by suppressing IRAK1 and TRAF6 expression in the SCI model. In contrast, miRNA-146a may be upregulated by inflammatory mediators via the IRAK1/TRAF6 pathway in the spinal cord. As a negative feedback element, miRNA-146a could make sure that the expression of IRAK1- and TRAF6-mediated genes was under tight control. Thus, miRNA-146a may serve as a novel therapeutic target for SCI interventions. PMID:27830143

  15. SciSpark: Highly Interactive and Scalable Model Evaluation and Climate Metrics

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Palamuttam, R. S.; Mogrovejo, R. M.; Whitehall, K. D.; Mattmann, C. A.; Verma, R.; Waliser, D. E.; Lee, H.

    2015-12-01

    Remote sensing data and climate model output are multi-dimensional arrays of massive sizes locked away in heterogeneous file formats (HDF5/4, NetCDF 3/4) and metadata models (HDF-EOS, CF) making it difficult to perform multi-stage, iterative science processing since each stage requires writing and reading data to and from disk. We are developing a lightning fast Big Data technology called SciSpark based on ApacheTM Spark under a NASA AIST grant (PI Mattmann). Spark implements the map-reduce paradigm for parallel computing on a cluster, but emphasizes in-memory computation, "spilling" to disk only as needed, and so outperforms the disk-based ApacheTM Hadoop by 100x in memory and by 10x on disk. SciSpark will enable scalable model evaluation by executing large-scale comparisons of A-Train satellite observations to model grids on a cluster of 10 to 1000 compute nodes. This 2nd generation capability for NASA's Regional Climate Model Evaluation System (RCMES) will compute simple climate metrics at interactive speeds, and extend to quite sophisticated iterative algorithms such as machine-learning based clustering of temperature PDFs, and even graph-based algorithms for searching for Mesocale Convective Complexes. We have implemented a parallel data ingest capability in which the user specifies desired variables (arrays) as several time-sorted lists of URL's (i.e. using OPeNDAP model.nc?varname, or local files). The specified variables are partitioned by time/space and then each Spark node pulls its bundle of arrays into memory to begin a computation pipeline. We also investigated the performance of several N-dim. array libraries (scala breeze, java jblas & netlib-java, and ND4J). We are currently developing science codes using ND4J and studying memory behavior on the JVM. On the pyspark side, many of our science codes already use the numpy and SciPy ecosystems. The talk will cover: the architecture of SciSpark, the design of the scientific RDD (sRDD) data structure, our

  16. SciSpark: Highly Interactive and Scalable Model Evaluation and Climate Metrics

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Mattmann, C. A.; Waliser, D. E.; Kim, J.; Loikith, P.; Lee, H.; McGibbney, L. J.; Whitehall, K. D.

    2014-12-01

    Remote sensing data and climate model output are multi-dimensional arrays of massive sizes locked away in heterogeneous file formats (HDF5/4, NetCDF 3/4) and metadata models (HDF-EOS, CF) making it difficult to perform multi-stage, iterative science processing since each stage requires writing and reading data to and from disk. We are developing a lightning fast Big Data technology called SciSpark based on ApacheTM Spark. Spark implements the map-reduce paradigm for parallel computing on a cluster, but emphasizes in-memory computation, "spilling" to disk only as needed, and so outperforms the disk-based ApacheTM Hadoop by 100x in memory and by 10x on disk, and makes iterative algorithms feasible. SciSpark will enable scalable model evaluation by executing large-scale comparisons of A-Train satellite observations to model grids on a cluster of 100 to 1000 compute nodes. This 2nd generation capability for NASA's Regional Climate Model Evaluation System (RCMES) will compute simple climate metrics at interactive speeds, and extend to quite sophisticated iterative algorithms such as machine-learning (ML) based clustering of temperature PDFs, and even graph-based algorithms for searching for Mesocale Convective Complexes. The goals of SciSpark are to: (1) Decrease the time to compute comparison statistics and plots from minutes to seconds; (2) Allow for interactive exploration of time-series properties over seasons and years; (3) Decrease the time for satellite data ingestion into RCMES to hours; (4) Allow for Level-2 comparisons with higher-order statistics or PDF's in minutes to hours; and (5) Move RCMES into a near real time decision-making platform. We will report on: the architecture and design of SciSpark, our efforts to integrate climate science algorithms in Python and Scala, parallel ingest and partitioning (sharding) of A-Train satellite observations from HDF files and model grids from netCDF files, first parallel runs to compute comparison statistics and PDF

  17. Novel Target for Ameliorating Pain and Other Problems after SCI: Spontaneous Activity in Nociceptors

    DTIC Science & Technology

    2016-06-01

    prediction that interventions that reduce the function of sodium ion channel Nav1.8 (primarily expressed in nociceptive primary afferent neurons) ameliorate...Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A, 104:8520–8525. Shields, SD, Ahn...gated sodium channel expressed by sensory neurons. Nature 379:257– 262. CrossRef Medline Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J

  18. [Analysis of acupuncture literatures published in Science Citation Index (SCI) periodicals in 2010].

    PubMed

    Xiang, Yan; Li, Rui

    2012-08-01

    Acupuncture-related literatures published in foreign medical journal in Science Citation Index (SCI) periodicals in 2010 were retrieved, summarized and analyzed. The result shows that the recognition of acupuncture clinic abroad was still in the initial period. Most of the researches were still remained in the section of clinical efficacy verification. There was comparatively less studies on its working mechanism. Traditional treatments according to differentiation of syndromes were still deficient in clinical researches. There were big differences on research results, however, most of the result equated therapeutic effect of acupuncture with placeboes. And it was lack of unified and standard estimation system on the effect of acupuncture.

  19. Measurement of Neutron and Muon Fluxes 100~m Underground with the SciBath Detector

    SciTech Connect

    Garrison, Lance

    2014-01-01

    The SciBath detector is an 80 liter liquid scintillator detector read out by a three dimensional grid of 768 wavelength-shifting fibers. Initially conceived as a fine-grained charged particle detector for neutrino studies that could image charged particle tracks in all directions, it is also sensitive to fast neutrons (15-200 MeV). In fall of 2011 the apparatus performed a three month run to measure cosmic-induced muons and neutrons 100~meters underground in the FNAL MINOS near-detector area. Data from this run has been analyzed and resulted in measurements of the cosmic muon flux as \

  20. Highlights from day three of the EuroSciCon 2015 Sports Science Summit

    PubMed Central

    Chawla, Amit; McGregor, Alison

    2015-01-01

    This EuroSciCon Sports Science Summit represented a significant gathering of leading professionals in the field of sports science. The conference was held on 13–15 January 2015 at the O2 arena, London, UK. The chairman on the third day was Mr Greg Robertson, a specialist trainee Orthopedic surgeon from Edinburgh. The conference attracted over 80 attendants from all over the world, with 32 presentations from invited speakers and peer-reviewed submissions. This meeting report provides a summary of the best abstracts from the conference. PMID:28031889

  1. Transposon-Assisted Genetic Engineering with Mos1-Mediated Single-Copy Insertion (MosSCI).

    PubMed

    Frøkjær-Jensen, Christian

    2015-01-01

    Transgenesis in model organisms is necessary to determine the function, expression, and subcellular localization of gene products. In Caenorhabditis elegans, injected DNA can be propagated as multicopy extrachromosomal arrays but transgenes in arrays are mosaic, over-expressed in some tissues and silenced in the germline. Here, a method to insert a transgene into a specific genomic location called Mos1-mediated single-copy insertion (MosSCI) is described. Single-copy insertion allows transgene expression at levels that approximate endogenous gene expression as well as expression in the germline.

  2. [Analysis on acupuncture related articles published in periodicals in science citation index (SCI) in 2008].

    PubMed

    Wang, Chao; He, Wen-Ju; Guo, Yi

    2010-09-01

    Acupuncture related articles published in periodicals in Science Citation Index (SCI) in 2008 were summarized and analyzed. About 583 articles were collected using "acupuncture" and "in 2008" as keywords in the Web of Science data base by information retrieval. These papers were summarized and analyzed from various aspects of country, language, subject category, literature type, publication sources, impact factor, research method, acupoints, disease category and needling methods by using Excel software combined with manual sorting of the literature, the aim is to provide a reference for domestic acupuncture research.

  3. SciFinder Scholar 2006: an empirical analysis of research topic query processing.

    PubMed

    Wagner, A Ben

    2006-01-01

    Topical search queries in SciFinder Scholar are processed through an extensive set of natural language processing algorithms that greatly enhance the relevance and comprehensiveness of the search results. Little detailed documentation on these algorithms has been published. However, a careful examination of the highlighted hit terms coupled with a comparison of results from small variations in query language reveal much additional, useful information about these algorithms. An understanding of how these algorithms work can lead to better search results and explain many unexpected results, including differing hit counts for singular versus plural query words and phrases.

  4. What's Manifest in the History of SciTech: Reflections on The History Manifesto.

    PubMed

    Kevles, Daniel J

    2016-06-01

    Making nuts-and-bolts public policy is not--and never has been--the long suit of professional historians, but general historical work, whatever its durée, has done a good deal to shape discourse on public issues. Jo Guldi and David Armitage neglect that fact, as well as the opinion-shaping influence of history conveyed via nonprint media. They also ignore the large body of scholarship produced in all media during recent decades in the history of science, technology, and science-related medicine (SciTech), even though SciTech itself looms enormously large in the modern era as an instrument of national and international security, a driver of the economy, and a transformer of medicine, public health, and the environment. Much of this scholarship, even though of short durée, can illuminate salient contemporary issues, including innovation; patronage and practice; government and policy; imperialism and globalization; intellectual property; science and religion; and human rights, environment, energy, and disasters.

  5. Performance Engineering Research Institute SciDAC-2 Enabling Technologies Institute Final Report

    SciTech Connect

    Hall, Mary

    2014-09-19

    Enhancing the performance of SciDAC applications on petascale systems has high priority within DOE SC. As we look to the future, achieving expected levels of performance on high-end com-puting (HEC) systems is growing ever more challenging due to enormous scale, increasing archi-tectural complexity, and increasing application complexity. To address these challenges, PERI has implemented a unified, tripartite research plan encompassing: (1) performance modeling and prediction; (2) automatic performance tuning; and (3) performance engineering of high profile applications. The PERI performance modeling and prediction activity is developing and refining performance models, significantly reducing the cost of collecting the data upon which the models are based, and increasing model fidelity, speed and generality. Our primary research activity is automatic tuning (autotuning) of scientific software. This activity is spurred by the strong user preference for automatic tools and is based on previous successful activities such as ATLAS, which has automatically tuned components of the LAPACK linear algebra library, and other re-cent work on autotuning domain-specific libraries. Our third major component is application en-gagement, to which we are devoting approximately 30% of our effort to work directly with Sci-DAC-2 applications. This last activity not only helps DOE scientists meet their near-term per-formance goals, but also helps keep PERI research focused on the real challenges facing DOE computational scientists as they enter the Petascale Era.

  6. Building a Universal Nuclear Energy Density Functional (UNEDF). SciDAC-2 Project

    SciTech Connect

    Vary, James P.; Carlson, Joe; Furnstahl, Dick; Horoi, Mihai; Lusk, Rusty; Nazarewicz, Witek; Ng, Esmond; Thompson, Ian

    2012-09-29

    An understanding of the properties of atomic nuclei is crucial for a complete nuclear theory, for element formation, for properties of stars, and for present and future energy and defense applications. During the period of Dec. 1 2006 – Jun. 30, 2012, the UNEDF collaboration carried out a comprehensive study of all nuclei, based on the most accurate knowledge of the strong nuclear interaction, the most reliable theoretical approaches, the most advanced algorithms, and extensive computational resources, with a view towards scaling to the petaflop platforms and beyond. Until recently such an undertaking was hard to imagine, and even at the present time such an ambitious endeavor would be far beyond what a single researcher or a traditional research group could carry out. The UNEDF SciDAC project has developed several key computational codes and algorithms for reaching the goal of solving the nuclear quantum many-body problem throughout the chart of nuclei. Without such developments, scientific progress would not be possible. In addition the UNEDF SciDAC successfully applied these developments to solve many forefront research problems.

  7. Scientific support of SciTech museum exhibits and outreach programs

    SciTech Connect

    Peshkin, M.

    1995-08-01

    SciTech (Science and Technology Interactive Center) is a small hands-on science museum located in Aurora, Illinois, not far from Argonne National Laboratory. Its constituency includes prosperous suburbs and economically disadvantaged minority communities in Aurora and Chicago. Its mission is to contribute to the country`s scientific literacy initiative by offering hands-on experiences on the museum floor and through outreach programs extended to school children, their teachers, and other groups. Argonne`s participation is focused mainly on the development of exhibits to carry the ideas of modern science and technology to the public. This is an area in which traditional museums are weak, but in which SciTech has become a nationally recognized leader with the assistance of Argonne, Fermilab, nearby technological companies, and many volunteer scientists and engineers. We also participate in development and improvement of the museum`s general exhibits and outreach programs. Argonne`s Director, Alan Schriesheim, serves as a member of the museum`s Board of Directors. Murray Peshkin serves part-time as the museum`s Senior Scientist. Dale Henderson serves part-time as an exhibit developer. That work is supported by the Laboratory Director`s discretionary funds. In addition, several members of the Physics Division voluntarily assist with exhibit development and the Division makes facilities available for that effort.

  8. SciDAC - The Scientific Data Management Center (http://sdmcenter.lbl.gov)

    SciTech Connect

    Ling Liu Calton Pu

    2005-06-20

    In SciDAC SDM project, the main assignment to the Georgia Institute of Technology team (according to the proposed work) is to develop advanced information extraction and information integration technologies on top of the XWRAP technology originated from Georgia Tech [LPH01]. We have developed XWRAPComposer technology to enable the XWRAP code generator to generate Java information wrappers that are capable of extraction of data from multiple linked pages. These information wrappers are used as gateways or adaptors for scientific information mediators to access and fuse interesting data and answering complex queries over a large collection of heterogeneous scientific information sources. Our accomplishments over the SciDAC sponsored years (July 2001 to July 2004) can be summarized along two dimensions. Technically, we have produced a number of major software releases and published over 30 research papers in both international conferences and international journals. The planned software releases include 1. Five Java wrappers and five WDSL-enabled wrappers for SDM Pilot scenarios, which were released in early 2003, 2. The XWRAPComposer toolkit (command line version) which was first released in late 2003 and then released in Summer 2004, 3. Five Ptolemy wrapper actors which were released first in Summer 2003, and then released again in Fall 2005. 4. The decomposable XWRAPComposer actor in Ptolemy, which we have made it available as open source in end of 2004 and tested it in early 2005.

  9. Neuroinflammatory contributions to pain after SCI: roles for central glial mechanisms and nociceptor-mediated host defense.

    PubMed

    Walters, Edgar T

    2014-08-01

    Neuropathic pain after spinal cord injury (SCI) is common, often intractable, and can be severely debilitating. A number of mechanisms have been proposed for this pain, which are discussed briefly, along with methods for revealing SCI pain in animal models, such as the recently applied conditioned place preference test. During the last decade, studies of animal models have shown that both central neuroinflammation and behavioral hypersensitivity (indirect reflex measures of pain) persist chronically after SCI. Interventions that reduce neuroinflammation have been found to ameliorate pain-related behavior, such as treatment with agents that inhibit the activation states of microglia and/or astroglia (including IL-10, minocycline, etanercept, propentofylline, ibudilast, licofelone, SP600125, carbenoxolone). Reversal of pain-related behavior has also been shown with disruption by an inhibitor (CR8) and/or genetic deletion of cell cycle-related proteins, deletion of a truncated receptor (trkB.T1) for brain-derived neurotrophic factor (BDNF), or reduction by antisense knockdown or an inhibitor (AMG9810) of the activity of channels (TRPV1 or Nav1.8) important for electrical activity in primary nociceptors. Nociceptor activity is known to drive central neuroinflammation in peripheral injury models, and nociceptors appear to be an integral component of host defense. Thus, emerging results suggest that spinal and systemic effects of SCI can activate nociceptor-mediated host defense responses that interact via neuroinflammatory signaling with complex central consequences of SCI to drive chronic pain. This broader view of SCI-induced neuroinflammation suggests new targets, and additional complications, for efforts to develop effective treatments for neuropathic SCI pain.

  10. Transporter Protein-Coupled DPCPX Nanoconjugates Induce Diaphragmatic Recovery after SCI by Blocking Adenosine A1 Receptors

    PubMed Central

    Minic, Zeljka; Zhang, Yanhua; Mao, Guangzhao

    2016-01-01

    Respiratory complications in patients with spinal cord injury (SCI) are common and have a negative impact on the quality of patients' lives. Systemic administration of drugs that improve respiratory function often cause deleterious side effects. The present study examines the applicability of a novel nanotechnology-based drug delivery system, which induces recovery of diaphragm function after SCI in the adult rat model. We developed a protein-coupled nanoconjugate to selectively deliver by transsynaptic transport small therapeutic amounts of an A1 adenosine receptor antagonist to the respiratory centers. A single administration of the nanoconjugate restored 75% of the respiratory drive at 0.1% of the systemic therapeutic drug dose. The reduction of the systemic dose may obviate the side effects. The recovery lasted for 4 weeks (the longest period studied). These findings have translational implications for patients with respiratory dysfunction after SCI. SIGNIFICANCE STATEMENT The leading causes of death in humans following SCI are respiratory complications secondary to paralysis of respiratory muscles. Systemic administration of methylxantines improves respiratory function but also leads to the development of deleterious side effects due to actions of the drug on nonrespiratory sites. The importance of the present study lies in the novel drug delivery approach that uses nanotechnology to selectively deliver recovery-inducing drugs to the respiratory centers exclusively. This strategy allows for a reduction in the therapeutic drug dose, which may reduce harmful side effects and markedly improve the quality of life for SCI patients. PMID:27013674

  11. Development and psychometric characteristics of the SCI-QOL Bladder Management Difficulties and Bowel Management Difficulties item banks and short forms and the SCI-QOL Bladder Complications scale

    PubMed Central

    Tulsky, David S.; Kisala, Pamela A.; Tate, Denise G.; Spungen, Ann M.; Kirshblum, Steven C.

    2015-01-01

    Objective To describe the development and psychometric properties of the Spinal Cord Injury – Quality of Life (SCI-QOL) Bladder Management Difficulties and Bowel Management Difficulties item banks and Bladder Complications scale. Design Using a mixed-methods design, a pool of items assessing bladder and bowel-related concerns were developed using focus groups with individuals with spinal cord injury (SCI) and SCI clinicians, cognitive interviews, and item response theory (IRT) analytic approaches, including tests of model fit and differential item functioning. Setting Thirty-eight bladder items and 52 bowel items were tested at the University of Michigan, Kessler Foundation Research Center, the Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital, and the James J. Peters VA Medical Center, Bronx, NY. Participants Seven hundred fifty-seven adults with traumatic SCI. Results The final item banks demonstrated unidimensionality (Bladder Management Difficulties CFI = 0.965; RMSEA = 0.093; Bowel Management Difficulties CFI = 0.955; RMSEA = 0.078) and acceptable fit to a graded response IRT model. The final calibrated Bladder Management Difficulties bank includes 15 items, and the final Bowel Management Difficulties item bank consists of 26 items. Additionally, 5 items related to urinary tract infections (UTI) did not fit with the larger Bladder Management Difficulties item bank but performed relatively well independently (CFI = 0.992, RMSEA = 0.050) and were thus retained as a separate scale. Conclusion The SCI-QOL Bladder Management Difficulties and Bowel Management Difficulties item banks are psychometrically robust and are available as computer adaptive tests or short forms. The SCI-QOL Bladder Complications scale is a brief, fixed-length outcomes instrument for individuals with a UTI. PMID:26010964

  12. ScyFlow: An Environment for the Visual Specification and Execution of Scientific Workflows

    NASA Technical Reports Server (NTRS)

    McCann, Karen M.; Yarrow, Maurice; DeVivo, Adrian; Mehrotra, Piyush

    2004-01-01

    With the advent of grid technologies, scientists and engineers are building more and more complex applications to utilize distributed grid resources. The core grid services provide a path for accessing and utilizing these resources in a secure and seamless fashion. However what the scientists need is an environment that will allow them to specify their application runs at a high organizational level, and then support efficient execution across any given set or sets of resources. We have been designing and implementing ScyFlow, a dual-interface architecture (both GUT and APT) that addresses this problem. The scientist/user specifies the application tasks along with the necessary control and data flow, and monitors and manages the execution of the resulting workflow across the distributed resources. In this paper, we utilize two scenarios to provide the details of the two modules of the project, the visual editor and the runtime workflow engine.

  13. SciData: a data model and ontology for semantic representation of scientific data.

    PubMed

    Chalk, Stuart J

    2016-01-01

    With the move toward global, Internet enabled science there is an inherent need to capture, store, aggregate and search scientific data across a large corpus of heterogeneous data silos. As a result, standards development is needed to create an infrastructure capable of representing the diverse nature of scientific data. This paper describes a fundamental data model for scientific data that can be applied to data currently stored in any format, and an associated ontology that affords semantic representation of the structure of scientific data (and its metadata), upon which discipline specific semantics can be applied. Application of this data model to experimental and computational chemistry data are presented, implemented using JavaScript Object Notation for Linked Data. Full examples are available at the project website (Chalk in SciData: a scientific data model. http://stuchalk.github.io/scidata/, 2016).

  14. VACET: Proposed SciDAC2 Visualization and Analytics Center forEnabling Technologies

    SciTech Connect

    Bethel, W.; Johnson, Chris; Hansen, Charles; Parker, Steve; Sanderson, Allen; Silva, Claudio; Tricoche, Xavier; Pascucci, Valerio; Childs, Hank; Cohen, Jonathon; Duchaineau, Mark; Laney, Dan; Lindstrom,Peter; Ahern, Sean; Meredith, Jeremy; Ostrouchov, George; Joy, Ken; Hamann, Bernd

    2006-06-19

    This paper accompanies a poster that is being presented atthe SciDAC 2006 meeting in Denver, CO. This project focuses on leveragingscientific visualization and analytics software technology as an enablingtechnology for increasing scientific productivity and insight. Advancesincomputational technology have resultedin an "information big bang,"which in turn has createda significant data understanding challenge. Thischallenge is widely acknowledged to be one of the primary bottlenecks incontemporary science. The vision for our Center is to respond directly tothat challenge by adapting, extending, creating when necessary anddeploying visualization and data understanding technologies for ourscience stakeholders. Using an organizational model as a Visualizationand Analytics Center for Enabling Technologies (VACET), we are wellpositioned to be responsive to the needs of a diverse set of scientificstakeholders in a coordinated fashion using a range of visualization,mathematics, statistics, computer and computational science and datamanagement technologies.

  15. Open for collaboration: an academic platform for drug discovery and development at SciLifeLab.

    PubMed

    Arvidsson, Per I; Sandberg, Kristian; Forsberg-Nilsson, Karin

    2016-10-01

    The Science for Life Laboratory Drug Discovery and Development (SciLifeLab DDD) platform reaches out to Swedish academia with an industry-standard infrastructure for academic drug discovery, supported by earmarked funds from the Swedish government. In this review, we describe the build-up and operation of the platform, and reflect on our first two years of operation, with the ambition to share learnings and best practice with academic drug discovery centers globally. We also discuss how the Swedish Teacher Exemption Law, an internationally unique aspect of the innovation system, has shaped the operation. Furthermore, we address how this investment in infrastructure and expertise can be utilized to facilitate international collaboration between academia and industry in the best interest of those ultimately benefiting the most from translational pharmaceutical research - the patients.

  16. Recent progress in CdTe solar cell research at SCI

    NASA Astrophysics Data System (ADS)

    Sasala, R. A.; Powell, R. C.; Dorer, G. L.; Reiter, N.

    1997-02-01

    Research at Solar Cells Inc. is focused on developing processes which will lead to high volume and low cost manufacturing of solar cells and to increase the performance of our present technology. The process research has focused on developing vapor transport deposition of the semiconductors, eliminating wet chemistry steps while minimizing the chloride treatment time, forming a low-loss back contact using only dry processing, and an improved interconnection technique. The performance improvement work has focused on the increase of the photocurrent by a combination of more transparent glass substrates and a thinner CdS window layer deposited on an i-SnO2 buffer layer. SCI record 13.0% 1 cm2 devices have been fabricated using these techniques. Stability monitoring continues and shows minimal degradation for over 20,000 hours of continuous light soak at 0.8 sun illumination.

  17. The Virtual Earth-Solar Observatory of the SCiESMEX

    NASA Astrophysics Data System (ADS)

    De la Luz, V.; Gonzalez-Esparza, A.; Cifuentes-Nava, G.

    2015-12-01

    The Mexican Space Weather Service (SCiESMEX, http://www.sciesmex.unam.mx) started operations in October 2014. The project includes the Virtual Earth-Solar Observatory (VESO, http://www.veso.unam.mx). The VESO is a improved project wich objetive is integrate the space weather instrumentation network from the National Autonomous University of Mexico (UNAM). The network includes the Mexican Array Radiotelescope (MEXART), the Callisto receptor (MEXART), a Neutron Telescope, a Cosmic Ray Telescope. the Schumann Antenna, the National Magnetic Service, and the mexican GPS network (TlalocNet). The VESO facility is located at the Geophysics Institute campus Michoacan (UNAM). We offer the service of data store, real-time data, and quasi real-time data. The hardware of VESO includes a High Performance Computer (HPC) dedicated specially to big data storage.

  18. Extraordinary tools for extraordinary science: the impact of SciDAC on accelerator science and technology

    NASA Astrophysics Data System (ADS)

    Ryne, Robert D.

    2006-09-01

    Particle accelerators are among the most complex and versatile instruments of scientific exploration. They have enabled remarkable scientific discoveries and important technological advances that span all programs within the DOE Office of Science (DOE/SC). The importance of accelerators to the DOE/SC mission is evident from an examination of the DOE document, ''Facilities for the Future of Science: A Twenty-Year Outlook.'' Of the 28 facilities listed, 13 involve accelerators. Thanks to SciDAC, a powerful suite of parallel simulation tools has been developed that represent a paradigm shift in computational accelerator science. Simulations that used to take weeks or more now take hours, and simulations that were once thought impossible are now performed routinely. These codes have been applied to many important projects of DOE/SC including existing facilities (the Tevatron complex, the Relativistic Heavy Ion Collider), facilities under construction (the Large Hadron Collider, the Spallation Neutron Source, the Linac Coherent Light Source), and to future facilities (the International Linear Collider, the Rare Isotope Accelerator). The new codes have also been used to explore innovative approaches to charged particle acceleration. These approaches, based on the extremely intense fields that can be present in lasers and plasmas, may one day provide a path to the outermost reaches of the energy frontier. Furthermore, they could lead to compact, high-gradient accelerators that would have huge consequences for US science and technology, industry, and medicine. In this talk I will describe the new accelerator modeling capabilities developed under SciDAC, the essential role of multi-disciplinary collaboration with applied mathematicians, computer scientists, and other IT experts in developing these capabilities, and provide examples of how the codes have been used to support DOE/SC accelerator projects.

  19. PACIFIC: the readout ASIC for the SciFi Tracker of the upgraded LHCb detector

    NASA Astrophysics Data System (ADS)

    Mazorra, J.; Chanal, H.; Comerma, A.; Gascón, D.; Gómez, S.; Han, X.; Pillet, N.; Vandaele, R.

    2016-02-01

    The LHCb detector will be upgraded during the Long Shutdown 2 (LS2) of the LHC in order to cope with higher instantaneous luminosities and will switch to a 40 MHz readout rate using a trigger-less software based system. All front-end electronics will be replaced and several sub-detectors must be redesigned to cope with the higher detector occupancy and radiation damage. The current tracking detectors downstream of the LHCb dipole magnet will be replaced by the Scintillating Fibre (SciFi) Tracker. The SciFi Tracker will use scintillating fibres read out by Silicon Photomultipliers (SiPMs). State-of-the-art multi-channel SiPM arrays are being developed and a custom ASIC, called the low-Power ASIC for the sCIntillating FIbres traCker (PACIFIC), will be used to digitise the signals from the SiPMs. This article presents an overview of the R&D for the PACIFIC. It is a 64-channel ASIC implemented in 130 nm CMOS technology, aiming at a radiation tolerant design with a power consumption below 10 mW per channel. It interfaces directly with the SiPM anode through a current mode input, and provides a configurable non-linear 2-bit per channel digital output. The SiPM signal is acquired by a current conveyor and processed with a fast shaper and a gated integrator. The digitization is performed using a three threshold non-linear flash ADC operating at 40 MHz. Simulation and test results show the PACIFIC chip prototypes functioning well.

  20. Extraordinary Tools for Extraordinary Science: The Impact ofSciDAC on Accelerator Science&Technology

    SciTech Connect

    Ryne, Robert D.

    2006-08-10

    Particle accelerators are among the most complex and versatile instruments of scientific exploration. They have enabled remarkable scientific discoveries and important technological advances that span all programs within the DOE Office of Science (DOE/SC). The importance of accelerators to the DOE/SC mission is evident from an examination of the DOE document, ''Facilities for the Future of Science: A Twenty-Year Outlook''. Of the 28 facilities listed, 13 involve accelerators. Thanks to SciDAC, a powerful suite of parallel simulation tools has been developed that represent a paradigm shift in computational accelerator science. Simulations that used to take weeks or more now take hours, and simulations that were once thought impossible are now performed routinely. These codes have been applied to many important projects of DOE/SC including existing facilities (the Tevatron complex, the Relativistic Heavy Ion Collider), facilities under construction (the Large Hadron Collider, the Spallation Neutron Source, the Linac Coherent Light Source), and to future facilities (the International Linear Collider, the Rare Isotope Accelerator). The new codes have also been used to explore innovative approaches to charged particle acceleration. These approaches, based on the extremely intense fields that can be present in lasers and plasmas, may one day provide a path to the outermost reaches of the energy frontier. Furthermore, they could lead to compact, high-gradient accelerators that would have huge consequences for US science and technology, industry, and medicine. In this talk I will describe the new accelerator modeling capabilities developed under SciDAC, the essential role of multi-disciplinary collaboration with applied mathematicians, computer scientists, and other IT experts in developing these capabilities, and provide examples of how the codes have been used to support DOE/SC accelerator projects.

  1. Measurement of the nu(mu)-CCQE cross-section in the SciBooNE experiment

    SciTech Connect

    Alcaraz-Aunion, Jose Luis; Walding, Joseph; /Imperial Coll., London

    2009-09-01

    SciBooNE is a neutrino and anti-neutrino cross-section experiment at Fermilab, USA. The SciBooNE experiment is summarized and two independent CCQE analyses are described. For one of the analyses, an absolute {nu}{sub {mu}}-CCQE cross section in the neutrino energy region (0.6-1.6) GeV is shown and the technique developed for such a purpose is also explained. The total cross section measured over this energy range agrees well with expectations, based on the NEUT event generator and using a value of 1.21 GeV for the CCQE axial mass.

  2. SciNOvA: A Measurement of Neutrino-Nucleus Scattering in a Narrow-Band Beam

    SciTech Connect

    Paley, J.; Djurcic, Z.; Harris, D.; Tesarek, R.; Feldman, G.; Corwin, L.; Messier, M.D.; Mayer, N.; Musser, J.; Paley, J.; Tayloe, R.; /Indiana U. /Iowa State U. /Minnesota U. /South Carolina U. /Wichita State U. /William-Mary Coll.

    2010-10-15

    We propose to construct and deploy a fine-grained detector in the Fermilab NOvA 2 GeV narrow-band neutrino beam. In this beam, the detector can make unique contributions to the measurement of quasi-elastic scattering, neutral-current elastic scattering, neutral-current {pi}{sup 0} production, and enhance the NOvA measurements of electron neutrino appearance. To minimize cost and risks, the proposed detector is a copy of the SciBar detector originally built for the K2K long baseline experiment and used recently in the SciBooNE experiment.

  3. A Novel Approach for Effectively Treating SCI Pain, Improving Opioid Efficacy, and Preventing Opioid-Induced Constipation: Key Role of Toll-Like Receptor 4 (TLR4)

    DTIC Science & Technology

    2014-10-01

    Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Spinal cord injury (SCI) is a disabling and costly condition... Spinal cord injury (SCI) is a disabling and costly condition affecting wounded military personnel (1). SCI is also one of the leading causes of...of life for service-members, veterans, caretakers, and the general population. Keywords Spinal cord injury, central neuropathic pain, rat

  4. Measuring stigma after spinal cord injury: Development and psychometric characteristics of the SCI-QOL Stigma item bank and short form

    PubMed Central

    Kisala, Pamela A.; Tulsky, David S.; Pace, Natalie; Victorson, David; Choi, Seung W.; Heinemann, Allen W.

    2015-01-01

    Objective To develop a calibrated item bank and computer adaptive test (CAT) to assess the effects of stigma on health-related quality of life in individuals with spinal cord injury (SCI). Design Grounded-theory based qualitative item development methods, large-scale item calibration field testing, confirmatory factor analysis, and item response theory (IRT)-based psychometric analyses. Setting Five SCI Model System centers and one Department of Veterans Affairs medical center in the United States. Participants Adults with traumatic SCI. Main Outcome Measures SCI-QOL Stigma Item Bank Results A sample of 611 individuals with traumatic SCI completed 30 items assessing SCI-related stigma. After 7 items were iteratively removed, factor analyses confirmed a unidimensional pool of items. Graded Response Model IRT analyses were used to estimate slopes and thresholds for the final 23 items. Conclusions The SCI-QOL Stigma item bank is unique not only in the assessment of SCI-related stigma but also in the inclusion of individuals with SCI in all phases of its development. Use of confirmatory factor analytic and IRT methods provide flexibility and precision of measurement. The item bank may be administered as a CAT or as a 10-item fixed-length short form and can be used for research and clinical applications. PMID:26010973

  5. Therapeutic effects of anti-spastic medication on neuromuscular abnormalities in SCI: a system identification approach.

    PubMed

    Mirbagheri, M M; Kindig, M; Niu, X; Varoqui, D

    2013-01-01

    Previous attempts to investigate the effects of antispastic medications are limited to clinical studies using that use clinical evaluations to assess. Since these measures are neither objective nor quantitative, the therapeutic effects of such medications on neuromuscular properties have not been fully evaluated. In this study, as a first attempt, we examined the effect of tizanidine, an anti-spastic medication, on modification of the neuromuscular properties of patients with chronic incomplete spinal cord injury (SCI). Each patient was administered 2 mg of tizanidine four times per day for four weeks. The spastic ankle of each patient was evaluated at baseline (prior to any medication, and then 1, 2, and 4 weeks after the start of medication. The ankle was perturbed with a small-amplitude Pseudo-Random Binary Sequence (PRBS) perturbation at various positions over the ankle range-of-motion. A parallel-cascade system identification technique, which provides an objective and quantitative measure of neuromuscular properties, was used to calculate the intrinsic and reflex stiffness. The stiffness vs. joint angle trends were then calculated for each evaluation; these curves were compared across the intervention time to determine the recovery pattern (i.e. change over time) due to the tizanidine intervention. All patients exhibited decreases in reflex stiffness (which abnormally increase after SCI) due to the medication; however, patients were observed to exhibit multiple recovery patterns. For some patients, the reflex stiffness continuously reduced over the four-week intervention period, while for other patients, the decrease during the first week (i.e. between the baseline and 1-Week evaluations) was most pronounced. Also, some patients presented a significant decrease with time, while others presented no improvement in the intrinsic stiffness. These findings suggest that tizanidine may be effective in reducing not only reflex stiffness, but also the subject

  6. A preliminary study of intravenous surfactants in paraplegic dogs: polymer therapy in canine clinical SCI.

    PubMed

    Laverty, Peter H; Leskovar, Alenka; Breur, Gert J; Coates, Joan R; Bergman, Robert L; Widmer, William R; Toombs, James P; Shapiro, Scott; Borgens, Richard B

    2004-12-01

    Hydrophilic polymers, both surfactants and triblock polymers, are known to seal defects in cell membranes. In previous experiments using laboratory animals, we have exploited this capability using polyethylene glycol (PEG) to repair spinal axons after severe, standardized spinal cord injury (SCI) in guinea pigs. Similar studies were conducted using a related co-polymer Poloxamer 188 (P 188). Here we carried out initial investigations of an intravenous application of PEG or P 188 (3500 Daltons, 30% w/w in saline; 2 mL/kg I.V. and 2 mL/kg body weight or 300 mL P 188 per kg, respectively) to neurologically complete cases of paraplegia in dogs. Our aim was to first determine if this is a clinically safe procedure in cases of severe naturally occurring SCI in dogs. Secondarily, we wanted to obtain preliminary evidence if this therapy could be of clinical benefit when compared to a larger number of similar, but historical, control cases. Strict entry criteria permitted recruitment of only neurologically complete paraplegic dogs into this study. Animals were treated by a combination of conventional and experimental techniques within approximately 72 h of admission for spinal trauma secondary to acute, explosive disk herniation. Outcome measures consisted of measurements of voluntary ambulation, deep and superficial pain perception, conscious proprioception in hindlimbs, and evoked potentials (somatosensory evoked potentials [SSEP]). We determined that polymer injection is a safe adjunct to the conventional management of severe neurological injury in dogs. We did not observe any unacceptable clinical response to polymer injection; there were no deaths, nor any other problem arising from, or associated with, the procedures. Outcome measures over the 6-8-week trial were improved by polymer injection when compared to historical cases. This recovery was unexpectedly rapid compared to these comparator groups. The results of this pilot trial provides evidence consistent with the

  7. Observing Some Life Cycles. Teacher's Guide. Unit E3. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Chitepo, Thoko; And Others

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide contains instructional…

  8. Atoms and Molecules. 'O' Level. Teacher's Guide. Unit 2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 3.

    ERIC Educational Resources Information Center

    Mandizha, George

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the third year of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be used in…

  9. Using Electricity. Teacher's Guide. Unit I2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Chidume, Kwashira

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be used in…

  10. Understanding Electricity. Teacher's Guide. Unit I1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Chidume, Kwashira

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  11. Reactions of the rat musculoskeletal system to compressive spinal cord injury (SCI) and whole body vibration (WBV) therapy.

    PubMed

    Schwarz, A; Pick, C; Harrach, R; Stein, G; Bendella, H; Ozsoy, O; Ozsoy, U; Schoenau, E; Jaminet, P; Sarikcioglu, L; Dunlop, S; Angelov, D N

    2015-06-01

    Traumatic spinal cord injury (SCI) causes a loss of locomotor function with associated compromise of the musculo-skeletal system. Whole body vibration (WBV) is a potential therapy following SCI, but little is known about its effects on the musculo-skeletal system. Here, we examined locomotor recovery and the musculo-skeletal system after thoracic (T7-9) compression SCI in adult rats. Daily WBV was started at 1, 7, 14 and 28 days after injury (WBV1-WBV28 respectively) and continued over a 12-week post-injury period. Intact rats, rats with SCI but no WBV (sham-treated) and a group that received passive flexion and extension (PFE) of their hind limbs served as controls. Compared to sham-treated rats, neither WBV nor PFE improved motor function. Only WBV14 and PFE improved body support. In line with earlier studies we failed to detect signs of soleus muscle atrophy (weight, cross sectional diameter, total amount of fibers, mean fiber diameter) or bone loss in the femur (length, weight, bone mineral density). One possible explanation is that, despite of injury extent, the preservation of some axons in the white matter, in combination with quadripedal locomotion, may provide sufficient trophic and neuronal support for the musculoskeletal system.

  12. A Comprehensive Evaluation of H2SO4 formation from OH and sCI pathways in high BVOC environments

    NASA Astrophysics Data System (ADS)

    Kim, S.; Seco, R.; Park, J. H.; Guenther, A. B.; Smith, J. N.; Kuang, C.; Bustillos, J. O. V.; Tota, J.; Souza, R. A. F. D.

    2014-12-01

    The recently highlighted importance of stabilized Criegee intermediates (sCI) as an oxidant for atmospheric SO2 triggered a number of studies to assess the atmospheric implications of H2SO4 formation from the sCI reaction pathway. In addition, it has not been clear why new particle formation events are not observed in the Amazon rain forest. The mostly widely speculated reason has been a very low H2SO4 level. We will present quantitative assessments of SO2 oxidation by sCI leading to the H2SO4 production using a comprehensive observational dataset from a tropical rainforest study during the GOAmazon field campaign at the T3 site in Manacapuru, Amazonas, Brazil. To our best knowledge, this is the first observation of H2SO4 and OH in Amazon and is unique for all tropical sites due to the accompanying comprehensive gas and aerosol observations such as CO, NOX, SO2, VOCs, and physical and chemical characteristics of aerosols. We will discuss observed H2SO4 levels during the GOAmazon field campaigns to demonstrate 1) H2SO4 formation potential from OH and sCI oxidation pathways by contrasting extremely clean and relatively polluted air masses and 2) the Implications of the observed H2SO4 levels in new particle formation and particle growth events.

  13. What Do You Know about Water? Teacher's Guide. Unit D. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Dube, Peter

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  14. Reactions of the rat musculoskeletal system to compressive spinal cord injury (SCI) and whole body vibration (WBV) therapy

    PubMed Central

    Schwarz, A.; Pick, C.; Harrach, R.; Stein, G.; Bendella, H.; Ozsoy, O.; Ozsoy, U.; Schoenau, E.; Jaminet, P.; Sarikcioglu, L.; Dunlop, S.; Angelov, D.N.

    2015-01-01

    Traumatic spinal cord injury (SCI) causes a loss of locomotor function with associated compromise of the musculo-skeletal system. Whole body vibration (WBV) is a potential therapy following SCI, but little is known about its effects on the musculo-skeletal system. Here, we examined locomotor recovery and the musculo-skeletal system after thoracic (T7-9) compression SCI in adult rats. Daily WBV was started at 1, 7, 14 and 28 days after injury (WBV1-WBV28 respectively) and continued over a 12-week post-injury period. Intact rats, rats with SCI but no WBV (sham-treated) and a group that received passive flexion and extension (PFE) of their hind limbs served as controls. Compared to sham-treated rats, neither WBV nor PFE improved motor function. Only WBV14 and PFE improved body support. In line with earlier studies we failed to detect signs of soleus muscle atrophy (weight, cross sectional diameter, total amount of fibers, mean fiber diameter) or bone loss in the femur (length, weight, bone mineral density). One possible explanation is that, despite of injury extent, the preservation of some axons in the white matter, in combination with quadripedal locomotion, may provide sufficient trophic and neuronal support for the musculoskeletal system. PMID:26032204

  15. Our Planet Earth. Study Guide. Unit F1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Stocklmayer, Sue

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  16. "Publish SCI Papers or No Degree": Practices of Chinese Doctoral Supervisors in Response to the Publication Pressure on Science Students

    ERIC Educational Resources Information Center

    Li, Yongyan

    2016-01-01

    Publishing English papers in journals listed in Science Citation Index (SCI) has become a requirement for degree conferment for doctoral science students at many universities in China. The publication requirement engenders high pressure for doctoral students and their supervisors and shapes the politics of the relationship between the two parties.…

  17. Life, Beginning and Growing. Teacher's Guide. Unit E1. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  18. Reproducing by Flowers and Seeds. Teacher's Guide. Unit E2. ZIM-SCI, Zimbabwe Secondary School Science Project.

    ERIC Educational Resources Information Center

    Zesaguli, Josie

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  19. Sense from Senses. Teacher's Guide. Unit J. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Simango, Sam

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  20. Living Things and Their Food. Teacher's Guide. Unit G2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  1. Energy for Living. Teacher's Guide. Unit G1. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  2. Forces. Teacher's Guide. Units H1 and H2. ZIM-SCI, Zimbabwe Secondary School Science Project. Year 2.

    ERIC Educational Resources Information Center

    Dock, Alan; Hosking, Bunty

    The Zimbabwe Secondary School Science Project (ZIM-SCI) developed student study guides, corresponding teaching guides, and science kits for a low-cost science course which could be taught during the first 2 years of secondary school without the aid of qualified teachers and conventional laboratories. This teaching guide, designed to be read in…

  3. Measurement of the absolute vμ-CCQE cross section at the SciBooNE experiment

    SciTech Connect

    Aunion, Jose Luis Alcaraz

    2010-07-01

    This thesis presents the measurement of the charged current quasi-elastic (CCQE) neutrino-nucleon cross section at neutrino energies around 1 GeV. This measurement has two main physical motivations. On one hand, the neutrino-nucleon interactions at few GeV is a region where existing old data are sparse and with low statistics. The current measurement populates low energy regions with higher statistics and precision than previous experiments. On the other hand, the CCQE interaction is the most useful interaction in neutrino oscillation experiments. The CCQE channel is used to measure the initial and final neutrino fluxes in order to determine the neutrino fraction that disappeared. The neutrino oscillation experiments work at low neutrino energies, so precise measurement of CCQE interactions are essential for flux measurements. The main goal of this thesis is to measure the CCQE absolute neutrino cross section from the SciBooNE data. The SciBar Booster Neutrino Experiment (SciBooNE) is a neutrino and anti-neutrino scattering off experiment. The neutrino energy spectrum works at energies around 1 GeV. SciBooNE was running from June 8th 2007 to August 18th 2008. In that period, the experiment collected a total of 2.65 x 1020 protons on target (POT). This thesis has used full data collection in neutrino mode 0.99 x 1020 POT. A CCQE selection cut has been performed, achieving around 70% pure CCQE sample. A fit method has been exclusively developed to determine the absolute CCQE cross section, presenting results in a neutrino energy range from 0.2 to 2 GeV. The results are compatible with the NEUT predictions. The SciBooNE measurement has been compared with both Carbon (MiniBoonE) and deuterium (ANL and BNL) target experiments, showing a good agreement in both cases.

  4. Bibliometric analysis of the Korean Journal of Parasitology: measured from SCI, PubMed, Scopus, and Synapse databases.

    PubMed

    Lee, Choon Shil

    2009-10-01

    The Korean Journal of Parasitology (KJP) is the official journal of the Korean Society for Parasitology which is celebrating its 50th anniversary in 2009. To assess the contributions and achievements of the KJP, bibliometric analysis was conducted based on the citation data retrieved from 4 major databases; SCI, PubMed, Synapse, and Scopus. It was found that the KJP articles were constantly cited by the articles published in major international journals represented in these databases. More than 60% of 1,370 articles published in the KJP from 1963 to June 2009 were cited at least once by SCI articles. The overall average times cited by SCI articles are 2.6. The rate is almost 3 times higher for the articles published in the last 10 years compared to 1.0 for the articles of the 1960s. The SCI journal impact factor for 2008 is calculated as 0.871. It is increasing and it is expected to increase further with the introduction of the KJP in the database in 2008. The more realistic h-indices were measured from the study data set covering all the citations to the KJP; 17 for SCI, 6 for PubMed, 19 for Synapse, and 17 for Scopus. Synapse extensively picked up the citations to the earlier papers not retrievable from the other 3 databases. It identified many papers published in the 1960s and in the 1980s which have been cited heavily, proving the central role of the KJP in the dissemination of the important research findings over the last 5 decades.

  5. Sci-Fin: Visual Mining Spatial and Temporal Behavior Features from Social Media

    PubMed Central

    Pu, Jiansu; Teng, Zhiyao; Gong, Rui; Wen, Changjiang; Xu, Yang

    2016-01-01

    Check-in records are usually available in social services, which offer us the opportunity to capture and analyze users’ spatial and temporal behaviors. Mining such behavior features is essential to social analysis and business intelligence. However, the complexity and incompleteness of check-in records bring challenges to achieve such a task. Different from the previous work on social behavior analysis, in this paper, we present a visual analytics system, Social Check-in Fingerprinting (Sci-Fin), to facilitate the analysis and visualization of social check-in data. We focus on three major components of user check-in data: location, activity, and profile. Visual fingerprints for location, activity, and profile are designed to intuitively represent the high-dimensional attributes. To visually mine and demonstrate the behavior features, we integrate WorldMapper and Voronoi Treemap into our glyph-like designs. Such visual fingerprint designs offer us the opportunity to summarize the interesting features and patterns from different check-in locations, activities and users (groups). We demonstrate the effectiveness and usability of our system by conducting extensive case studies on real check-in data collected from a popular microblogging service. Interesting findings are reported and discussed at last. PMID:27999398

  6. Impact of SciDAC on accelerator projects across the office of science through electromagnetic modeling

    NASA Astrophysics Data System (ADS)

    Ko, K.; Folwell, N.; Ge, L.; Guetz, A.; Ivanov, V.; Kabel, A.; Kowalski, M.; Lee, L.; Li, Z.; Ng, C.; Prudencio, E.; Schussman, G.; Uplenchwar, R.; Xiao, L.; Collaborators, ISICs/SAPP

    2005-01-01

    Electromagnetic Modelling led by SLAC is a principal component of the "Advanced Computing for 21st Century Accelerator Science and Technology" SciDAC project funded through the Office of High Energy Physics. This large team effort comprises three other national laboratories (LBNL, LLNL, SNL) and six universities (CMU, Columbia, RPI, Stanford, UC Davis and U of Wisconsin) with the goal to develop a set of parallel electromagnetic codes based on unstructured grids to target challenging problems in accelerators, and solve them to unprecedented realism and accuracy. Essential to the code development are the collaborations with the ISICs/SAPP in eigensolvers, meshing, adaptive refinement, shape optimization and visualization (see "Achievements in ISICs/SAPP Collaborations for Electromagnetic Modelling of Accelerators"). Supported by these advances in computational science, we have successfully performed the large-scale simulations that have impacted important accelerator projects across the Office of Science (SC) including the Positron Electron Project (PEP) -II, Next Linear Collider (NLC) and the International Linear Collider (ILC) in High Energy Physics (HEP), the Rare Isotope Accelerator (RIA) in Nuclear Physics (NP) and the Linac Coherent Light Source (LCLS) in Basic Energy Science (BES).

  7. Measurement of neutrino induced charged current neutral pion production cross section at SciBooNE

    SciTech Connect

    Catala-Perez, Juan

    2014-01-01

    SciBooNE is a neutrino scattering experiment located in the Booster Neutrino Beam at Fermilab. It collected data from June 2007 to August 2008 to accurately measure muon neutrino and anti-neutrino cross sections on carbon around 1 GeV neutrino energy. In this thesis we present the results on the measurement of the muon neutrino cross section resulting in a μ- plus a single π0 final state (CC- π0 channel). The present work will show the steps taken to achieve this result: from the reconstruction improvements to the background extraction. The flux-averaged CC - π0 production cross section measurement obtained in this thesis < σCC- π0 > Φ = (5.6 ± 1.9fit ± 0.7beam ± 0.5int - 0.7det) × 10-40 cm2/N at an average energy of 0.89 GeV is found to agree well both with the expectation from the Monte Ca

  8. Sci-Fin: Visual Mining Spatial and Temporal Behavior Features from Social Media.

    PubMed

    Pu, Jiansu; Teng, Zhiyao; Gong, Rui; Wen, Changjiang; Xu, Yang

    2016-12-20

    Check-in records are usually available in social services, which offer us the opportunity to capture and analyze users' spatial and temporal behaviors. Mining such behavior features is essential to social analysis and business intelligence. However, the complexity and incompleteness of check-in records bring challenges to achieve such a task. Different from the previous work on social behavior analysis, in this paper, we present a visual analytics system, Social Check-in Fingerprinting (Sci-Fin), to facilitate the analysis and visualization of social check-in data. We focus on three major components of user check-in data: location, activity, and profile. Visual fingerprints for location, activity, and profile are designed to intuitively represent the high-dimensional attributes. To visually mine and demonstrate the behavior features, we integrate WorldMapper and Voronoi Treemap into our glyph-like designs. Such visual fingerprint designs offer us the opportunity to summarize the interesting features and patterns from different check-in locations, activities and users (groups). We demonstrate the effectiveness and usability of our system by conducting extensive case studies on real check-in data collected from a popular microblogging service. Interesting findings are reported and discussed at last.

  9. Assessing ComSciCon 2013: A science communication workshop for STEM graduate students (Invited)

    NASA Astrophysics Data System (ADS)

    Kohler, S.; Ranjan, S.; Sanders, N.; Morey, S.

    2013-12-01

    We report on the efficacy of Communicating Science 2013, a science communication workshop for graduate students. Effective science communication is imperative for the sharing of scientific ideas, continued funding and support from policy makers, and education of the public. Science graduate students are a prime group to target for communication training, as they will be our future scientists, educators, and EPO professionals. To this end, Communicating Science 2013 (ComSciCon), a workshop organized by and for STEM graduate students, was held in June of this year. This workshop taught graduate students from around the nation to effectively communicate science to both their peers and the public. To learn about grad students' attitudes toward science communication and establish the workshop's efficacy, we surveyed the participants both before and after the workshop. This assessment probed topics such as communication preparation the participants have already received, how science communication is perceived in their home department, and what participants gained from the workshop. We report the results here.

  10. What Is Required In Uganda? The 2007 Report Of The Japan Sci-edu. Support Project

    NASA Astrophysics Data System (ADS)

    Uchida, Tatsuhiro

    2010-07-01

    The development of ability for technology and invention is required as self-sustaining growth of science and technology in Asian and African developing countries. Science education that connects to the real world is the required education for the self-sustaining growth. But in fact, it is very common to study for the entrance examination. According to C. Camilla, S. and Sjo/berg, [The Re-emergence of Values in the Science Curriculum. Rotterdam, 2007, Sense Publishers], Ugandan students are the most interested ones in science and technology (I would like to be a scientist, I would like to get a job in technology) in the world. Science education should mortgages future of youth. Especially science education of developing countries should be directly connected to the real world. Because they need a lot of engineers as skilled worker, we implemented physics education that was directly connected with manufacturing by the sci-edu. support project in Uganda. The best results were achieved by contrivance in spite of poverty area. Our education method gave one form of New Science Education in Asia and Africa.

  11. Final Technical Report - SciDAC Cooperative Agreement: Center for Wave Interactions with Magnetohydrodynamics

    SciTech Connect

    Schnack, Dalton D.

    2012-07-01

    Final technical report for research performed by Dr. Thomas G. Jenkins in collaboration with Professor Dalton D. Schnack on SciDAC Cooperative Agreement: Center for Wave Interactions with Magnetohydrodyanics, DE-FC02-06ER54899, for the period of 8/15/06 - 8/14/11. This report centers on the Slow MHD physics campaign work performed by Dr. Jenkins while at UW-Madison and then at Tech-X Corporation. To make progress on the problem of RF induced currents affect magnetic island evolution in toroidal plasmas, a set of research approaches are outlined. Three approaches can be addressed in parallel. These are: (1) Analytically prescribed additional term in Ohm's law to model the effect of localized ECCD current drive; (2) Introduce an additional evolution equation for the Ohm's law source term. Establish a RF source 'box' where information from the RF code couples to the fluid evolution; and (3) Carry out a more rigorous analytic calculation treating the additional RF terms in a closure problem. These approaches rely on the necessity of reinvigorating the computation modeling efforts of resistive and neoclassical tearing modes with present day versions of the numerical tools. For the RF community, the relevant action item is - RF ray tracing codes need to be modified so that general three-dimensional spatial information can be obtained. Further, interface efforts between the two codes require work as well as an assessment as to the numerical stability properties of the procedures to be used.

  12. [Systematic review of studies on quality of life indexed on the SciELO database].

    PubMed

    Landeiro, Graziela Macedo Bastos; Pedrozo, Celine Cristina Raimundo; Gomes, Maria José; Oliveira, Elizabete Regina de Araújo

    2011-10-01

    Interest in the quality of life construct has increased in the same proportion as the output of instruments to measure it. In order to analyze the scientific literature on the subject to provide a reflection on this construct in Brazil, a systematic review of the SciELO database covering the period from January 2001 to December 2006 was conducted. It was divided into 3 phases: the first involving 180 publications, the second 124, and the third 10. Of the 180 publications, 77.4% consisted of production in the last three years, with growth of 32.4% from 2001 to 2006. Of these, 124 were selected for methodological analysis in accordance with the category of the study: 79 (63.9%) instrument application articles; 25 (20.1%) translation, validation, adaptation and construction of a QOL instrument; 10 (8%) qualitative studies on QOL; 5 (4%) bibliographical review, 5 (4%) on the quality of life concept. The next stage involved the use of questionnaires and/or interview scripts in order to obtain a broader consensus on perceived quality of life from the interviewees. It was seen that there was significant scientific output in the period under scrutiny, with diversification of approaches and methodologies, highlighting the complexity of the quality of life construct.

  13. Lambda Station: Alternate network path forwarding for production SciDAC applications

    SciTech Connect

    Grigoriev, Maxim; Bobyshev, Andrey; Crawford, Matt; DeMar, Phil; Grigaliunas, Vyto; Moibenko, Alexander; Petravick, Don; Newman, Harvey; Steenberg, Conrad; Thomas, Michael; /Caltech

    2007-09-01

    The LHC era will start very soon, creating immense data volumes capable of demanding allocation of an entire network circuit for task-driven applications. Circuit-based alternate network paths are one solution to meeting the LHC high bandwidth network requirements. The Lambda Station project is aimed at addressing growing requirements for dynamic allocation of alternate network paths. Lambda Station facilitates the rerouting of designated traffic through site LAN infrastructure onto so-called 'high-impact' wide-area networks. The prototype Lambda Station developed with Service Oriented Architecture (SOA) approach in mind will be presented. Lambda Station has been successfully integrated into the production version of the Storage Resource Manager (SRM), and deployed at US CMS Tier1 center at Fermilab, as well as at US-CMS Tier-2 site at Caltech. This paper will discuss experiences using the prototype system with production SciDAC applications for data movement between Fermilab and Caltech. The architecture and design principles of the production version Lambda Station software, currently being implemented as Java based web services, will also be presented in this paper.

  14. Exploration tools for drug discovery and beyond: applying SciFinder to interdisciplinary research.

    PubMed

    Haldeman, Margaret; Vieira, Barbara; Winer, Fred; Knutsen, Lars J S

    2005-06-01

    Chemists have long recognized the value of online databases for surveying the literature of their field. Chemical Abstracts Service (CAS) databases covering almost a century's worth of journal articles and patent documents are among the best known and widely used for searching information on compounds. Today's research presents a new challenge, however, as the boundaries of chemistry and biological sciences overlap increasingly. This trend is especially true in the drug discovery field where published findings relating to both chemical and biological entities and their interactions are examined. CAS has expanded its resources to meet the requirements of the new, interdisciplinary challenges faced by today's researchers. This is evident both in the content of CAS databases, which have been expanded to include more biology-related information, and in the technology of the search tools now available to researchers on their desktop. It is the integration of content and search-and-retrieval technology that enables new insights to be made in the vast body of accumulated information. CAS's SciFinder is a widely used research tool for this purpose.

  15. OptoSci educator kits: an immediate solution to photonics teaching laboratories

    NASA Astrophysics Data System (ADS)

    Walsh, Douglas; Moodie, David; Mauchline, Iain; Johnstone, Walter; Culshaw, Brian

    2003-10-01

    The burgeoning growth of the worldwide photonics and optical communications industry has imposed ever increasing demands on the supply of suitably skilled engineers and scientists who can design, install and operate modern photonics systems. In recognition of this need OptoSci, in collaboration with university academics, has commercially developed a series of hardware based teaching packages in optics, optoelectronics and optical communications. Each educator kit is fully self-contained, including all of the optoelectronic hardware and comprehensive literature support. This saves the academic tutor considerable development time and enables the kits to be immediately installed in the photonics teaching laboratory to support accompanying lecture courses. A fundamental design objective of our educator kits is to provide students with hands-on practical experience of photonics components, instruments and systems and allow them to investigate essential physical principles and key technical issues relevant to their lecture courses. This paper will outline the design philosophy behind the products to meet the desired educational aims, and then examine the specific educational objectives and topics investigated in each educator kit.

  16. Public Data Set: Erratum: "Multi-point, high-speed passive ion velocity distribution diagnostic on the Pegasus Toroidal Experiment" [Rev. Sci. Instrum. 83, 10D516 (2012)

    SciTech Connect

    Burke, Marcus G.; Fonck, Raymond J.; Bongard, Michael W.; Schlossberg, David J.; Winz, Gregory R.

    2016-07-18

    This data set contains openly-documented, machine readable digital research data corresponding to figures published in M.G. Burke et al., 'Erratum: "Multi-point, high-speed passive ion velocity distribution diagnostic on the Pegasus Toroidal Experiment" [Rev. Sci. Instrum. 83, 10D516 (2012)],' Rev. Sci. Instrum. 87, 079902 (2016).

  17. Towards flash flood disaster prevention: the SciNetNat Haz proposal

    NASA Astrophysics Data System (ADS)

    Konstantinos, Papatheodorou; Elena, Tzanou; Carmen, Maftei; Ozgur, Kirca; Hafzullah, Aksoy

    2015-04-01

    Floods occur with a continuously increasing frequency due to climatic changes and cause serious damage in the wider Black Sea area, endangering human life and property. As societies continuously expand, these phenomena are expected to play an increasingly important role, blocking sustainable development unless properly tackled. Flash flood prevention seems at this point, to be the target of effectively mitigating the potential threat. Since in many cases, there is a cross-border character of the problem, collaborative efforts have to be made involving cooperation between countries. To this end, a variety of problems exist, including the "information gap" related to the unavailability of data and the multitude of methodologies used to assess flood hazard; a fact that renders comparison of hazard assessment results and cross border cooperation ineffective. An effort made within the context of the SciNetNatHaz project, suggests a two step approach to produce reliable the results which can lead to decision making regarding designing preventive measures. The first step aims at defining the flood prone areas on a regional scale, using geomorphometric models and readily available topographic data; thus overcoming the problem of data availability for any region of interest. The second step follows a vulnerability and risk assessment of the flood prone areas of interest and focuses on the calculation of flood parameters on a local scale using hydraulic models. Implementation of the full process is based on Open Source software tools so that it can be implemented with minimal costs by anyone interested. Implementation of the proposed procedure in three different cases in Greece and in Romania shows that it can provide accurate and reliable results to support decision making regarding the design of preventive measures. Keywords: Flash floods, hazard assessment, flood disaster prevention, HEC-RAS, SAGA GIS . Acknowledgements: This work is partially funded by the EU through the

  18. Reactivity of stabilized Criegee intermediates (sCI) from isoprene and monoterpene ozonolysis toward SO2 and organic acids

    NASA Astrophysics Data System (ADS)

    Sipilä, M.; Jokinen, T.; Berndt, T.; Richters, S.; Makkonen, R.; Donahue, N. M.; Mauldin, R. L., III; Kurten, T.; Paasonen, P.; Sarnela, N.; Ehn, M.; Junninen, H.; Rissanen, M. P.; Thornton, J.; Stratmann, F.; Herrmann, H.; Worsnop, D. R.; Kulmala, M.; Kerminen, V.-M.; Petäjä, T.

    2014-01-01

    Oxidation processes in Earth's atmosphere are tightly connected to many environmental and human health issues and are essential drivers for biogeochemistry. Until the recent discovery of the atmospheric relevance of stabilized Criegee intermediates (sCI), atmospheric oxidation processes were thought to be dominated by few main oxidants: ozone, hydroxyl radicals (OH), nitrate radicals and, e.g. over oceans, halogen atoms such as chlorine. Here, we report results from laboratory experiments at 293 K and atmospheric pressure focusing on sCI formation from the ozonolysis of isoprene and the most abundant monoterpenes (α-pinene and limonene), and subsequent reactions of the resulting sCIs with SO2 producing sulphuric acid (H2SO4). The measured sCI yields were (0.15 ± 0.07), (0.27 ± 0.12) and (0.58 ± 0.26) for the ozonolysis of α-pinene, limonene and isoprene, respectively. The ratio between the rate coefficient for the sCI loss (including thermal decomposition and the reaction with water vapour) and the rate coefficient for the reaction of sCI with SO2, k(loss) / k(sCI + SO2), was determined at relative humidities of 10% and 50%. Observed values represent the average reactivity of all sCIs produced from the individual alkene used in the ozonolysis. For the monoterpene derived sCIs, the relative rate coefficients k(loss) / k(sCI + SO2) were in the range (2.0-2.4) × 1012 molecule cm-3 and nearly independent on the relative humidity. This fact points to a minor importance of the sCI + H2O reaction in the case of the sCI arising from α-pinene and limonene. For the isoprene sCIs, however, the ratio k(loss) / k(sCI + SO2) was strongly dependent on the relative humidity. To explore whether sCIs could have a more general role in atmospheric oxidation, we investigated as an example the reactivity of acetone oxide (sCI from the ozonolysis of 2,3-dimethyl-2-butene) toward small organic acids, i.e. formic and acetic acid. Acetone oxide was found to react faster with the

  19. Exploring Earth and the Solar System: Educational Outreach Through NASA's Space Place, SciJinks, and Climate Kids Websites

    NASA Technical Reports Server (NTRS)

    Meneses, Joseph Chistopher

    2012-01-01

    NASA's Space Place team publishes engaging content and creates an effective environment to inspire a young audience to dare mighty things. NASA uses the Space Place, Climate Kids, and SciJinks websites to cultivate interest among elementary-school-aged children in both science and technology. During my summer internship at Jet Propulsion Laboratory I used Adobe Flash and ActionScript 3 to develop content for the Space Place, Climate Kids, and SciJinks sites. In addition, I was involved in the development process for ongoing and new projects during my internship. My involvement allowed me to follow a project from concept to design, implementation, and release. I personally worked on three projects this summer, two of which are currently in deployment. The first is a scrambled letter-tile guessing game titled Solar System Scramble. The second, Butterfrog Mix-Up, is a rotating-tile puzzle game. The third project is a unfinished prototype for a maze game.

  20. [Letters to the editor published in Peruvian biomedical journals indexed in SciELO-Peru 2006-2013].

    PubMed

    Montenegro-Idrogo, Juan José; Mejía-Dolores, Jhon William; Chalco-Huamán, Joel L

    2015-01-01

    This bibliometric study describes the characteristics of letters to the editor published between 2006-2013 in biomedical journals indexed in SciELO-Peru.253 letters (10.3% of total publications) were collected. Most letters (139) were in the Peruvian Journal of Experimental Medicine and Public Health, with marked increase throughout those years. 25% of letters submitted included medical student participation. 14% of authors presented with international affiliations and 27% with endogenous affiliation - common in university journals (Anales de la Facultad de Medicina, Revista Médica Herediana).The usual criteria justifying the publication of letters were: opinion of medical fact or public domain (35.6%) and discussion of results, methodological flaws or interpretation (22.9%). In biomedical journals indexed in SciELO Peru the letters to the editor comprise a percentage of publications that has increased in recent years, with low publication of letters of findings or primary data, compared with opinion or criticism.

  1. Clinical Trial of AC105 (Mg/PEG) for Treatment of Acute Spinal Cord Injury (SCI). Phase 2

    DTIC Science & Technology

    2013-10-01

    505-9. Kwon BK, Roy J, Lee JH, Okon E, Zhang H, Marx JC, Kindy MS. (2009) Magnesium chloride in a polyethylene glycol formulation as a...13. SUPPLEMENTARY NOTES 14. ABSTRACT Acorda Therapeutics, Inc. is developing the polymer formulation of magnesium , known as AC-105...15. SUBJECT TERMS AC-105, Magnesium , Mg, Spinal Cord Injury, SCI 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF

  2. Development of a Small Molecule P2X7R Antagonist as a Treatment for Acute SCI

    DTIC Science & Technology

    2013-10-01

    microglia in response to SCI, and of the role of P2X7 receptor activation in that process . Indeed, in parallel work using uninjured human brain tissue...distinct glial fates are instructed, and how that process may be manipulated for therapeutic purposes. Thus, on the basis of the injury-associated...autocrine loop for the self -maintenance of glial progenitors, the perturbation of which might dictate progenitor recruitment as either reactive glia or

  3. Development of a Small Molecule P2X7R Antagonist as a Treatment for Acute SCI

    DTIC Science & Technology

    2011-10-01

    evaluated the impact of deletion of connexins (Cx30/Cx43) in astrocytes on post-traumatic ATP release. In vivo bioluminescence imaging showed a...Introduction The proposed studies were based on the observati on that ATP release and activation of P2X7 receptors drives the innate inf lammatory...tissue swelling. Prior studies have shown that excess ive ATP release from peri-traumatic regions contributes to the inflammatory response to SCI by

  4. Development of a Small Molecule P2X7R Antagonist as a Treatment for Acute SCI

    DTIC Science & Technology

    2011-10-01

    impact of deletion of connexins (Cx30/Cx43) in astrocytes on post-traumatic ATP release. In vivo bioluminescence imaging showed a significant reduction...the observation that ATP release and activation of P2X7 receptors drives the innate inflammatory response initiated by spinal cord injury. P2X7R...swelling. Prior studies have shown that excessive ATP release from peri-traumatic regions contributes to the inflammatory response to SCI by

  5. SCI1, the first member of the tissue-specific inhibitors of CDK (TIC) class, is probably connected to the auxin signaling pathway

    PubMed Central

    DePaoli, Henrique; Goldman, Gustavo; Goldman, Maria-Helena

    2012-01-01

    The recent finding of a tissue-specific cell cycle regulator (SCI1) that inhibits cell proliferation/differentiation in the upper pistil points to an unanticipated way of controlling plant morphogenesis. The similarity between the SCI1 RNAi-silenced plants and some auxin-related phenotypes suggested that SCI1 could be involved in the auxin signaling pathway. To address this hypothesis, we analyzed the expression of three auxin-related genes in transgenic plants in which SCI1 was silenced and overexpressed. The results showed that the expression levels of the auxin-related genes largely correlated with the SCI1 expression level. Additionally, we analyzed the Arabidopsis SCI1 upstream regulatory region and found putative cis-acting elements also present in the AtCYCB1;1 AtYUC1, AtYUC2 and AtYUC4 URRs, suggesting a cell cycle- and auxin-related transcriptional regulation. Based on our previous and the current studies, we propose SCI1 as a signal transducer engaging auxin signaling and cell division/differentiation. PMID:22301969

  6. Hydrogen and the First Stars: First Results from the SCI-HI 21-cm all-sky spectrum experiment

    NASA Astrophysics Data System (ADS)

    Voytek, Tabitha; Peterson, Jeffrey; Lopez-Cruz, Omar; Jauregui-Garcia, Jose-Miguel; SCI-HI Experiment Team

    2015-01-01

    The 'Sonda Cosmologica de las Islas para la Deteccion de Hidrogeno Neutro' (SCI-HI) experiment is an all-sky 21-cm brightness temperature spectrum experiment studying the cosmic dawn (z~15-35). The experiment is a collaboration between Carnegie Mellon University (CMU) and Instituto Nacional de Astrofísica, Óptica y Electrónica (INAOE) in Mexico. Initial deployment of the SCI-HI experiment occurred in June 2013 on Guadalupe; a small island about 250 km off of the Pacific coast of Baja California in Mexico. Preliminary measurements from this deployment have placed the first observational constraints on the 21-cm all-sky spectrum around 70 MHz (z~20), see Voytek et al (2014).Neutral Hydrogen (HI) is found throughout the universe in the cold gas that makes up the intergalactic medium (IGM). HI can be observed through the spectral line at 21 cm (1.4 GHz) due to hyperfine structure. Expansion of the universe causes the wavelength of this spectral line to stretch at a rate defined by the redshift z, leading to a signal which can be followed through time.Now the strength of the 21-cm signal in the IGM is dependent only on a small number of variables; the temperature and density of the IGM, the amount of HI in the IGM, the UV energy density in the IGM, and the redshift. This means that 21-cm measurements teach us about the history and structure of the IGM. The SCI-HI experiment focuses on the spatially averaged 21-cm spectrum, looking at the temporal evolution of the IGM during the cosmic dawn before reionization.Although the SCI-HI experiment placed first constraints with preliminary data, this data was limited to a narrow frequency regime around 60-85 MHz. This limitation was caused by instrumental difficulties and the presence of residual radio frequency interference (RFI) in the FM radio band (~88-108 MHz). The SCI-HI experiment is currently undergoing improvements and we plan to have another deployment soon. This deployment would be to Socorro and Clarion, two

  7. GENESIS SciFlo: Scientific Knowledge Creation on the Grid Using a Semantically-Enabled Dataflow Execution Environment

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Manipon, G.; Tang, B.; Mazzoni, D.; Fetzer, E.; Dobinson, E.; Yunck, T.

    2005-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo is a system for Scientific Knowledge Creation on the Grid using a Semantically-Enabled Dataflow Execution Environment. SciFlo leverages Simple Object Access Protocol (SOAP) Web Services and the Grid Computing standards (WS-* & Globus Alliance toolkits), and enables scientists to do multi-instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. The scientist injects a distributed computation into the Grid by simply filling

  8. GENESIS SciFlo: Choreographing Interoperable Web Services on the Grid using a Semantically-Enabled Dataflow Execution Environment

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Manipon, G.; Xing, Z.

    2007-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo leverages remote Web Services, called via Simple Object Access Protocol (SOAP) or REST (one-line) URLs, and the Grid Computing standards (WS-* & Globus Alliance toolkits), and enables scientists to do multi- instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. In particular, SciFlo exploits the wealth of datasets accessible by OpenGIS Consortium (OGC) Web Mapping Servers & Web Coverage Servers (WMS/WCS), and by Open Data

  9. The Fulldome Curriculum for the Spitz SciDome Digital Planetarium: A New Age for Planetarium Education

    NASA Astrophysics Data System (ADS)

    Bradstreet, David H.; Huggins, S. L.

    2010-01-01

    Astronomy education received a huge boost from the Space Program in the 1960's and early 1970's as evidenced by a large increase in school planetariums built nationwide at that time. But with the waning of manned explorations so also went the push for astronomy in the schools, and many school planetariums are underutilized or not used at all. This poster will discuss and illustrate some of the new Fulldome Curriculum that has been developed specifically for the Spitz SciDome digital planetarium powered by Starry Night. It is now possible to teach astronomical concepts in new and exciting ways and present topics that were extremely difficult to convey to lay audiences in the past. One of the strongest advantages of the SciDome is that, since it uses Starry Night as its astronomical engine, students can create their own astronomical configurations in the computer lab or at home using the PC or Mac version and then simply load them onto the SciDome planetarium system and display them for the class on the dome. Additionally, the instructor can create artificial bodies to pose "What if” scenarios, for example, "What would the Moon look like if it didn't rotate synchronously?", or "What would the analemma look like if the Earth's orbit were circular and not an ellipse?" Topics covered in the series include The Moon, Seasons, Coordinate Systems, Roemer's Method of Measuring the Speed of Light, Analemmas in the Solar System, Precession, Mimas and the Cassini Division, Halley's Comet in 1910, Dog Days, Galactic Distributions of Celestial Bodies, Retrograde Paths of Mars, Mercury's Orbit and the Length of the Mercurian Day, Altitude of the North Celestial Pole, Why Polaris Appears Mostly Stationary, Circumpolar Contellations, Planet Definition, Scale of the Solar System, Stonehenge, The Changing Aspect of Saturn's Appearance and Scorpio's Claws.

  10. Observation of cosmic ray hadrons at the top of the Sierra Negra volcano in Mexico with the SciCRT prototype

    SciTech Connect

    Ortiz, E.; Valdés-Galicia, J. F.; Matsubara, Y.; Nagai, Y.; Hurtado, A.; Musalem, O.; García, R.; Anzorena, M. A.; González, L. X.; Itow, Y.; Sako, T.; Lopez, D.; Sasai, Y.; Munakata, K.; Kato, C.; Kozai, M.; Shibata, S.; Takamaru, H.; Kojima, H.; Watanabe, K.; Tsuchiya, H.; Koi, T.

    2016-02-16

    In this study we report the flux of protons and neutral emission measured at the top of the Sierra Negra volcano at 4600 m.a.s.l. (575 g/cm2), in Eastern Mexico. As an example of the capability of the mini-SciCR as a cosmic ray detector we present the Forbush decrease recorded on March 7, 2012. These data were obtained with a cosmic ray detector prototype called mini-SciCR that was operating from October 2010 to July 2012. Our main aims were to measure the hadronic component flux of the secondary cosmic ray and to show the appropriate performance of all system of the detector. To separate the signals of protons from other charged particles we obtained the energy deposition pattern when they cross the detector using a Monte Carlo simulation, and to separate the signals of neutral emission we used an anticoincidence system between the edge bars and the internal bars of the detector. The mini-SciCR is a prototype of a new cosmic ray detector called SciBar Cosmic Ray Telescope (SciCRT) installed in the same place, which is in the process of calibration. The SciCRT will work mainly as a Solar Neutron and Muon Telescope, it is designed to achieve: (1) larger effective area than the current Solar Neutron Telescope, (2) higher energy resolution to determine the energy spectrum of solar neutrons, (3) lower energy threshold, and (4) higher particle identification ability.

  11. Observation of cosmic ray hadrons at the top of the Sierra Negra volcano in Mexico with the SciCRT prototype

    NASA Astrophysics Data System (ADS)

    Ortiz, E.; Valdés-Galicia, J. F.; Matsubara, Y.; Nagai, Y.; Hurtado, A.; Musalem, O.; García, R.; Anzorena, M. A.; González, L. X.; Itow, Y.; Sako, T.; Lopez, D.; Sasai, Y.; Munakata, K.; Kato, C.; Kozai, M.; Shibata, S.; Takamaru, H.; Kojima, H.; Watanabe, K.; Tsuchiya, H.; Koi, T.

    2016-11-01

    In this work we report the flux of protons and neutral emission measured at the top of the Sierra Negra volcano at 4600 m.a.s.l. (575 g/cm2), in Eastern Mexico. As an example of the capability of the mini-SciCR as a cosmic ray detector we present the Forbush decrease recorded on March 7, 2012. These data were obtained with a cosmic ray detector prototype called mini-SciCR that was operating from October 2010 to July 2012. Our main aims were to measure the hadronic component flux of the secondary cosmic ray and to show the appropriate performance of all system of the detector. To separate the signals of protons from other charged particles we obtained the energy deposition pattern when they cross the detector using a Monte Carlo simulation, and to separate the signals of neutral emission we used an anticoincidence system between the edge bars and the internal bars of the detector. The mini-SciCR is a prototype of a new cosmic ray detector called SciBar Cosmic Ray Telescope (SciCRT) installed in the same place, which is in the process of calibration. The SciCRT will work mainly as a Solar Neutron and Muon Telescope, it is designed to achieve: (1) larger effective area than the current Solar Neutron Telescope, (2) higher energy resolution to determine the energy spectrum of solar neutrons, (3) lower energy threshold, and (4) higher particle identification ability.

  12. DOE's SciDAC Visualization and Analytics Center for EnablingTechnologies -- Strategy for Petascale Visual Data Analysis Success

    SciTech Connect

    Bethel, E Wes; Johnson, Chris; Aragon, Cecilia; Rubel, Oliver; Weber, Gunther; Pascucci, Valerio; Childs, Hank; Bremer, Peer-Timo; Whitlock, Brad; Ahern, Sean; Meredith, Jeremey; Ostrouchov, George; Joy, Ken; Hamann, Bernd; Garth, Christoph; Cole, Martin; Hansen, Charles; Parker, Steven; Sanderson, Allen; Silva, Claudio; Tricoche, Xavier

    2007-10-01

    The focus of this article is on how one group of researchersthe DOE SciDAC Visualization and Analytics Center for EnablingTechnologies (VACET) is tackling the daunting task of enabling knowledgediscovery through visualization and analytics on some of the world slargest and most complex datasets and on some of the world's largestcomputational platforms. As a Center for Enabling Technology, VACET smission is the creation of usable, production-quality visualization andknowledge discovery software infrastructure that runs on large, parallelcomputer systems at DOE's Open Computing facilities and that providessolutions to challenging visual data exploration and knowledge discoveryneeds of modern science, particularly the DOE sciencecommunity.

  13. The effect of complex rehabilitation training for 12 weeks on trunk muscle function and spine deformation of patients with SCI.

    PubMed

    Sung, Dong-Hun; Yoon, Seong-Deok; Park, Gi Duck

    2015-03-01

    [Purpose] It is important for patients with incomplete spinal cord injury (SCI) to strengthen their muscle strength and return to the work force one of the ultimate objectives of rehabilitation. This study reports how a single patient with SCI became stabilized in terms of abdominal muscles and back extension muscles, as well as returning the back to the neutral position from spinal deformation, as result of complex exercises performed for 12 weeks. [Subjects] The degree of damage of the subject was rated as C grade. The subject of this study had unstable posture due to paralysis in the lower extremities of the left side after removal of a malignant tumor by surgical operation, and tilting and torsion in the pelvis increased followed by increase of kyphosis in the thoracolumbar spine. The subject was more than two years since diagnosis of incomplete SCI after surgery. [Methods] Using isokinetic lumbar muscle strength measurement equipment, peak torque/weight, total work and average power in flexion and extension of the lumbar region were measured. A trunk measurement system (Formetric 4D, DIERS, Germany), which is a 3D image processing apparatus with high resolution for vertebrae, was used in order to measure 3D vertebrae and pelvis deformation as well as static balance abilities. As an exercise method, a foam roller was used to conduct fascia relaxation massage for warming-up, and postural kyphosis was changed into postural lordosis by lat pull-down using equipment, performed in 5 sets of 15 times preset at 60% intensity of 1RM 4 set of 10 crunch exercises per set using Togu's were done while sitting at the end of Balance pad, and 4 sets of 15 bridge exercises. [Results] All angular speed tests showed a gradual increase in muscle strength. Flexion and extension showed 10% and 3% improvements, respectively. The spine deformation test showed that isokinetic exercise and lat pull-down exercise for 12 weeks resulted in improved spinal shape. [Conclusion] In this study

  14. Development of a Small Molecule P2X7R Antagonist as a Treatment for Acute SCI

    DTIC Science & Technology

    2012-10-01

    brain edema. Methods Mice. Aqp4−/− mice were generated by GenOway by cloning and sequencing of a targeted region of the murine Aqp4 gene in a 129/Sv... genetic back- ground. The strategy was to design a targeted locus allowing us to delete exons 1–3 to avoid any expression of putative splice variants...was made on the back region and a laminectomy was performed aseptically at the T11-T12 level. Before SCI, a catheter was placed in the left femoral

  15. DOE SciDAC's Earth System Grid Center for Enabling Technologies Final Report

    SciTech Connect

    Williams, Dean N.

    2011-09-27

    report at the end of project funding. To continue to serve the climate-science community, we are currently seeking additional funding. Such funding would allow us to maintain and enhance ESGF production and operation of this vital endeavor of cataloging, serving, and analyzing ultra-scale climate science data. At this time, the entire ESG-CET team would like to take this opportunity to sincerely thank our funding agencies in the DOE Scientific Discovery through Advanced Computing (SciDAC) program and the Office of Biological and Environmental Research (OBER) - as well as our national and international collaborators, stakeholders, and partners - for allowing us to work with you and serve the community these past several years.

  16. Challenges of animal models in SCI research: Effects of pre-injury task-specific training in adult rats before lesion.

    PubMed

    May, Zacnicte; Fouad, Karim; Shum-Siu, Alice; Magnuson, David S K

    2015-09-15

    A rarely explored subject in animal research is the effect of pre-injury variables on behavioral outcome post-SCI. Low reporting of such variables may underlie some discrepancies in findings between laboratories. Particularly, intensive task-specific training before a SCI might be important, considering that sports injuries are one of the leading causes of SCI. Thus, individuals with SCI often underwent rigorous training before their injuries. In the present study, we asked whether training before SCI on a grasping task or a swimming task would influence motor recovery in rats. Swim pre-training impaired recovery of swimming 2 and 4 weeks post-injury. This result fits with the idea of motor learning interference, which posits that learning something new may disrupt learning of a new task; in this case, learning strategies to compensate for functional loss after SCI. In contrast to swimming, grasp pre-training did not influence grasping ability after SCI at any time point. However, grasp pre-trained rats attempted to grasp more times than untrained rats in the first 4 weeks post-injury. Also, lesion volume of grasp pre-trained rats was greater than that of untrained rats, a finding which may be related to stress or activity. The increased participation in rehabilitative training of the pre-trained rats in the early weeks post-injury may have potentiated spontaneous plasticity in the spinal cord and counteracted the deleterious effect of interference and bigger lesions. Thus, our findings suggest that pre-training plays a significant role in recovery after CNS damage and needs to be carefully controlled for.

  17. Midlatitude Aerosol-Cloud-Radiation Feedbacks in Marine Boundary Layer Clouds

    DTIC Science & Technology

    2011-09-30

    frontal Continental Stratus , J. Atmos. Sci. 67, 3368-3383. [referred] Mechem, D. B., Y. L. Kogan, D. Shultz, 2010: Large Eddy Simulations of Post...frontal Continental Stratus . J. Atmos. Sci. 67, pp. 3835-3853. [referred] Melnikov, V. M., D. S. Zrnic, R. J. Doviak, P. B. Chilson, D. B. Mechem, and Y

  18. Observations of the Convective Environment in Developing and Non-developing Tropical Disturbances

    DTIC Science & Technology

    2012-01-01

    1111–1143. Fang J, Zhang F. 2010. Initial development and genesis of hurricane Dolly (2008). J. Atmos. Sci. 67: 655–672. Fierro AO, Zipser EJ, Lemone MA...Bosart LF. 2005. Mesoscale observations of the genesis of hurricane Dolly (1996). J. Atmos. Sci. 62: 3151–3171. Ritchie EA, Holland GJ. 1999. Large

  19. An Observational Study of Tropical-Cyclone Spin-Up in Supertyphoon Jangmi (2008) from 24 - 27 September

    DTIC Science & Technology

    2012-01-01

    multiscale vortices in the development of Hurricane 1 Dolly (2008), J. Atmos. Sci., 68, 103-122, 2011. 2 Franklin, J. L., Black, M. L., and Valde, K...Hurricane Dolly (1996), J. Atmos. Sci., 62, 3151–3171, 2005. 17 Reasor, P. D., Eastin, M. D., and Gamache, J. F.: Rapidly intensifying Hurricane Guillermo 18

  20. Measuring self-esteem after spinal cord injury: Development, validation and psychometric characteristics of the SCI-QOL Self-esteem item bank and short form

    PubMed Central

    Kalpakjian, Claire Z.; Tate, Denise G.; Kisala, Pamela A.; Tulsky, David S.

    2015-01-01

    Objective To describe the development and psychometric properties of the Spinal Cord Injury-Quality of Life (SCI-QOL) Self-esteem item bank. Design Using a mixed-methods design, we developed and tested a self-esteem item bank through the use of focus groups with individuals with SCI and clinicians with expertise in SCI, cognitive interviews, and item-response theory- (IRT) based analytic approaches, including tests of model fit, differential item functioning (DIF) and precision. Setting We tested a pool of 30 items at several medical institutions across the United States, including the University of Michigan, Kessler Foundation, the Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital, and the James J. Peters/Bronx Department of Veterans Affairs hospital. Participants A total of 717 individuals with SCI completed the self-esteem items. Results A unidimensional model was observed (CFI = 0.946; RMSEA = 0.087) and measurement precision was good (theta range between −2.7 and 0.7). Eleven items were flagged for DIF; however, effect sizes were negligible with little practical impact on score estimates. The final calibrated item bank resulted in 23 retained items. Conclusion This study indicates that the SCI-QOL Self-esteem item bank represents a psychometrically robust measurement tool. Short form items are also suggested and computer adaptive tests are available. PMID:26010972

  1. Measuring resilience after spinal cord injury: Development, validation and psychometric characteristics of the SCI-QOL Resilience item bank and short form

    PubMed Central

    Victorson, David; Tulsky, David S.; Kisala, Pamela A.; Kalpakjian, Claire Z.; Weiland, Brian; Choi, Seung W.

    2015-01-01

    Objective To describe the development and psychometric properties of the Spinal Cord Injury - Quality of Life (SCI-QOL) Resilience item bank and short form. Design Using a mixed-methods design, we developed and tested a resilience item bank through the use of focus groups with individuals with SCI and clinicians with expertise in SCI, cognitive interviews, and item-response theory based analytic approaches, including tests of model fit and differential item functioning (DIF). Setting We tested a 32-item pool at several medical institutions across the United States, including the University of Michigan, Kessler Foundation, the Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital and the James J. Peters/Bronx Department of Veterans Affairs medical center. Participants A total of 717 individuals with SCI completed the Resilience items. Results A unidimensional model was observed (CFI = 0.968; RMSEA = 0.074) and measurement precision was good (theta range between −3.1 and 0.9). Ten items were flagged for DIF, however, after examination of effect sizes we found this to be negligible with little practical impact on score estimates. The final calibrated item bank resulted in 21 retained items. Conclusion This study indicates that the SCI-QOL Resilience item bank represents a psychometrically robust measurement tool. Short form items are also suggested and computer adaptive tests are available. PMID:26010971

  2. Measurement of Neutrino-Nucleon Neutral-Current Elastic Scattering Cross-section at SciBooNE

    SciTech Connect

    Takei, Hideyuki

    2009-02-01

    In this thesis, results of neutrino-nucleon neutral current (NC) elastic scattering analysis are presented. Neutrinos interact with other particles only with weak force. Measurement of cross-section for neutrino-nucleon reactions at various neutrino energy are important for the study of nucleon structure. It also provides data to be used for beam flux monitor in neutrino oscillation experiments. The cross-section for neutrino-nucleon NC elastic scattering contains the axial vector form factor GA(Q2) as well as electromagnetic form factors unlike electromagnetic interaction. GA is propotional to strange part of nucleon spin (Δs) in Q2 → 0 limit. Measurement of NC elastic cross-section with smaller Q2 enables us to access Δs. NC elastic cross-sections of neutrino-nucleon and antineutrino-nucleon were measured earlier by E734 experiment at Brookheaven National Laboratory (BNL) in 1987. In this experiment, cross-sections were measured in Q2 > 0.4 GeV2 region. Result from this experiment was the only published data for NC elastic scattering cross-section published before our experiment. SciBooNE is an experiment for the measurement of neutrino-nucleon scattering cross-secitons using Booster Neutrino Beam (BNB) at FNAL. BNB has energy peak at 0.7 GeV. In this energy region, NC elastic scattering, charged current elastic scattering, charged current pion production, and neutral current pion production are the major reaction branches. SciBar, electromagnetic calorimeter, and Muon Range Detector are the detectors for SciBooNE. The SciBar consists of finely segmented scintillators and 14336 channels of PMTs. It has a capability to reconstruct particle track longer than 8 cm and separate proton from muons and pions using energy deposit information. Signal of NC elastic scattering is a single proton track. In vp → vp process, the recoil proton is detected. On the other hand, most of vn → vn is

  3. Toward Sci-φ: A Lightweight Cloud PaaS for Developing Embarrassingly Parallel Applications Based on Jini

    PubMed Central

    2014-01-01

    Embarrassingly parallel problems are characterised by a very small amount of information to be exchanged among the parts they are split in, during their parallel execution. As a consequence they do not require sophisticated, low-latency, high-bandwidth interconnection networks but can be efficiently computed in parallel by exploiting commodity hardware. Basically, this means cheap clusters, networks of workstations and desktops, and Computational Clouds. This computational model can be exploited to compute a quite large range of problems. This paper describes Sci-φ, an almost complete redesign of a previous tool of ours aimed at developing task parallel applications based on Java and Jini that were shown to be an effective and efficient solution in environments like clusters and networks of workstations and desktops. PMID:24701174

  4. System Configuration and Operation Plan of Hayabusa2 DCAM3-D Camera System for Scientific Observation During SCI Impact Experiment

    NASA Astrophysics Data System (ADS)

    Ogawa, Kazunori; Shirai, Kei; Sawada, Hirotaka; Arakawa, Masahiko; Honda, Rie; Wada, Koji; Ishibashi, Ko; Iijima, Yu-ichi; Sakatani, Naoya; Nakazawa, Satoru; Hayakawa, Hajime

    2017-03-01

    An artificial impact experiment is scheduled for 2018-2019 in which an impactor will collide with asteroid 162137 Ryugu (1999 JU3) during the asteroid rendezvous phase of the Hayabusa2 spacecraft. The small carry-on impactor (SCI) will shoot a 2-kg projectile at 2 km/s to create a crater 1-10 m in diameter with an expected subsequent ejecta curtain of a 100-m scale on an ideal sandy surface. A miniaturized deployable camera (DCAM3) unit will separate from the spacecraft at about 1 km from impact, and simultaneously conduct optical observations of the experiment. We designed and developed a camera system (DCAM3-D) in the DCAM3, specialized for scientific observations of impact phenomenon, in order to clarify the subsurface structure, construct theories of impact applicable in a microgravity environment, and identify the impact point on the asteroid. The DCAM3-D system consists of a miniaturized camera with a wide-angle and high-focusing performance, high-speed radio communication devices, and control units with large data storage on both the DCAM3 unit and the spacecraft. These components were successfully developed under severe constraints of size, mass and power, and the whole DCAM3-D system has passed all tests verifying functions, performance, and environmental tolerance. Results indicated sufficient potential to conduct the scientific observations during the SCI impact experiment. An operation plan was carefully considered along with the configuration and a time schedule of the impact experiment, and pre-programed into the control unit before the launch. In this paper, we describe details of the system design concept, specifications, and the operating plan of the DCAM3-D system, focusing on the feasibility of scientific observations.

  5. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 27: Knowledge diffusion and US government technology policy: Issues and opportunities for sci/tech librarians

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Hannah, Stan; Lawrence, Barbara; Kennedy, John M.

    1992-01-01

    Federal involvement in simulating economic growth through the development and application of technology policy is currently the subject of serious debate. A recession and the recognition that an internationally competitive economy is a prerequisite for the attainment of national goals have fostered a number of technology policy initiatives aimed at improving the economic competitiveness of American industry. This paper suggests that the successful implementation of U.S. technology policy will require the adoption of a knowledge diffusion model, the development of user oriented information products and services, and a more 'activist' approach on the part of sci/tech librarians in the provision of scientific and technical information (STI). These changes will have a dramatic impact on the sci/tech library of the future and the preparation of sci/tech librarians.

  6. NASA/DoD Aerospace Knowledge Diffusion Research Project. XXVII - Knowledge diffusion and U.S. government technology policy: Issues and opportunities for sci/tech librarians

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Hannah, Stan; Lawrence, Barbara; Kennedy, John M.

    1992-01-01

    Federal involvement in stimulating economic growth through the development and application of technology policy is currently the subject of serious debate. A recession and the recognition that an internationally competitive economy is a prerequisite for the attainment of national goals have fostered a number of technology policy initiatives aimed at improving the economic competitiveness of American industry. This paper suggests that the successful implementation of U.S. technology policy will require the adoption of a knowledge diffusion model, the development of user oriented information products and services, and a more 'activist' approach on the part of sci/tech librarians in the provision of scientific and technical information (STI). These changes will have a dramatic impact on the sci/tech library of the future and the preparation of sci/tech librarians.

  7. A high-resolution atlas of the infrared spectrum of the sun and the earth atmosphere from space. A compilation of ATMOS spectra of the region from 650 to 4800 cm-1 (2.3 to 16 microns). Volume 2: Stratosphere and mesosphere, 650 to 3350 cm-1

    NASA Technical Reports Server (NTRS)

    Farmer, Crofton B.; Norton, Robert H.

    1989-01-01

    During the period April 29 to May 2, 1985, the Atmospheric Trace Molecule Spectroscopy (ATMOS) experiment was operated for the first time, as part of the Spacelab-3 payload of the shuttle Challenger. The principal purpose of this experiment was to study the distributions of the atmosphere's minor and trace molecular constituents. The instrument, a modified Michelson interferometer covering the frequency range from 600 to 5000/cm-1 at a spectral resolution of 0.01/cm-1, recorded infrared absorption spectra of the sun and of the earth's atmosphere at times close to entry into and exit from occultation by the earth's limb. Spectra were obtained that are free from absorptions due to constituents of the atmosphere (i.e., they are pure solar spectra), as well as spectra of the atmosphere itself, covering line-of-sight tangent altitudes that span the range from the lower thermosphere to the bottom of the troposphere. This atlas presents a compilation of these spectra arranged in a hardcopy format suitable for quick-look reference purposes. Volume 2 covers the stratosphere and mesosphere (i.e., tangent altitudes from 20 to 80 km) for frequencies from 650 to 3350/cm-1.

  8. Observation of cosmic ray hadrons at the top of the Sierra Negra volcano in Mexico with the SciCRT prototype

    DOE PAGES

    Ortiz, E.; Valdés-Galicia, J. F.; Matsubara, Y.; ...

    2016-02-16

    In this study we report the flux of protons and neutral emission measured at the top of the Sierra Negra volcano at 4600 m.a.s.l. (575 g/cm2), in Eastern Mexico. As an example of the capability of the mini-SciCR as a cosmic ray detector we present the Forbush decrease recorded on March 7, 2012. These data were obtained with a cosmic ray detector prototype called mini-SciCR that was operating from October 2010 to July 2012. Our main aims were to measure the hadronic component flux of the secondary cosmic ray and to show the appropriate performance of all system of themore » detector. To separate the signals of protons from other charged particles we obtained the energy deposition pattern when they cross the detector using a Monte Carlo simulation, and to separate the signals of neutral emission we used an anticoincidence system between the edge bars and the internal bars of the detector. The mini-SciCR is a prototype of a new cosmic ray detector called SciBar Cosmic Ray Telescope (SciCRT) installed in the same place, which is in the process of calibration. The SciCRT will work mainly as a Solar Neutron and Muon Telescope, it is designed to achieve: (1) larger effective area than the current Solar Neutron Telescope, (2) higher energy resolution to determine the energy spectrum of solar neutrons, (3) lower energy threshold, and (4) higher particle identification ability.« less

  9. Leg joint power output during progressive resistance FES-LCE cycling in SCI subjects: developing an index of fatigue

    PubMed Central

    Haapala, Stephenie A; Faghri, Pouran D; Adams, Douglas J

    2008-01-01

    Background The purpose of this study was to investigate the biomechanics of the hip, knee and ankle during a progressive resistance cycling protocol in an effort to detect and measure the presence of muscle fatigue. It was hypothesized that knee power output can be used as an indicator of fatigue in order to assess the cycling performance of SCI subjects. Methods Six spinal cord injured subjects (2 incomplete, 4 complete) between the ages of twenty and fifty years old and possessing either a complete or incomplete spinal cord injury at or below the fourth cervical vertebra participated in this study. Kinematic data and pedal forces were recorded during cycling at increasing levels of resistance. Ankle, knee and hip power outputs and resultant pedal force were calculated. Ergometer cadence and muscle stimulation intensity were also recorded. Results The main findings of this study were: (a) ankle and knee power outputs decreased, whereas hip power output increased with increasing resistance, (b) cadence, stimulation intensity and resultant pedal force in that combined order were significant predictors of knee power output and (c) knowing the value of these combined predictors at 10 rpm, an index of fatigue can be developed, quantitatively expressing the power capacity of the knee joint with respect to a baseline power level defined as fatigue. Conclusion An index of fatigue was successfully developed, proportionalizing knee power capacity during cycling to a predetermined value of fatigue. The fatigue index value at 0/8th kp, measured 90 seconds into active, unassisted pedaling was 1.6. This indicates initial power capacity at the knee to be 1.6 times greater than fatigue. The fatigue index decreased to 1.1 at 2/8th kp, representing approximately a 30% decrease in the knee's power capacity within a 4 minute timespan. These findings suggest that the present cycling protocol is not sufficient for a rider to gain the benefits of FES and thus raises speculation as to

  10. Measurement of K+ production cross section by 8 GeV protons using high-energy neutrino interactions in the SciBooNE detector

    NASA Astrophysics Data System (ADS)

    Cheng, G.; Mariani, C.; Alcaraz-Aunion, J. L.; Brice, S. J.; Bugel, L.; Catala-Perez, J.; Conrad, J. M.; Djurcic, Z.; Dore, U.; Finley, D. A.; Franke, A. J.; Giganti, C.; Gomez-Cadenas, J. J.; Guzowski, P.; Hanson, A.; Hayato, Y.; Hiraide, K.; Jover-Manas, G.; Karagiorgi, G.; Katori, T.; Kobayashi, Y. K.; Kobilarcik, T.; Kubo, H.; Kurimoto, Y.; Louis, W. C.; Loverre, P. F.; Ludovici, L.; Mahn, K. B. M.; Masuike, S.; Matsuoka, K.; McGary, V. T.; Metcalf, W.; Mills, G. B.; Mitsuka, G.; Miyachi, Y.; Mizugashira, S.; Moore, C. D.; Nakajima, Y.; Nakaya, T.; Napora, R.; Nienaber, P.; Orme, D.; Otani, M.; Russell, A. D.; Sanchez, F.; Shaevitz, M. H.; Shibata, T.-A.; Sorel, M.; Stefanski, R. J.; Takei, H.; Tanaka, H.-K.; Tanaka, M.; Tayloe, R.; Taylor, I. J.; Tesarek, R. J.; Uchida, Y.; van de Water, R.; Walding, J. J.; Wascko, M. O.; White, H. B.; Yokoyama, M.; Zeller, G. P.; Zimmerman, E. D.

    2011-07-01

    The SciBooNE Collaboration reports K+ production cross section and rate measurements using high-energy daughter muon neutrino scattering data off the SciBar polystyrene (C8H8) target in the SciBooNE detector. The K+ mesons are produced by 8 GeV protons striking a beryllium target in Fermilab Booster Neutrino Beam line (BNB). Using observed neutrino and antineutrino events in SciBooNE, we measure (d2σ)/(dpdΩ)=(5.34±0.76)mb/(GeV/c×sr) for p+Be→K++X at mean K+ energy of 3.9 GeV and angle (with respect to the proton beam direction) of 3.7 degrees, corresponding to the selected K+ sample. Compared to Monte Carlo predictions using previous higher energy K+ production measurements, this measurement, which uses the NUANCE neutrino interaction generator, is consistent with a normalization factor of 0.85±0.12. This agreement is evidence that the extrapolation of the higher energy K+ measurements to an 8 GeV beam energy using Feynman scaling is valid. This measurement reduces the error on the K+ production cross section from 40% to 14%.

  11. The NASA SCI Files[TM]: The Case of the Shaky Quake. A Lesson Guide with Activities in Mathematics, Science, and Technology.

    ERIC Educational Resources Information Center

    Ricles, Shannon

    The NASA SCI Files is a series of instructional programs consisting of broadcast, print, and online elements emphasizing standards-based instruction, problem-based learning, and science as inquiry. The series seeks to motivate students in grades 3-5 to become critical thinkers and active problem solvers. In this program, the tree house detectives…

  12. The Case of the Physical Fitness Challenge: An Educator Guide with Activities in Mathematics, Science, and Technology. The NASA SCI Files. EG-2005-10-09-LARC

    ERIC Educational Resources Information Center

    Ricles, Shannon; Jaramillo, Becky; Fargo, Michelle

    2005-01-01

    In this companion to the "NASA SCI Files[TM]" episode "The Case of the Physical Fitness Challenge," the tree house detectives learn about anatomy, fitness and nutrition in preparation for the President's Challenge. The guide is divided into four segments aimed at grades 3-5, each of which includes an overview, a set of objectives, vocabulary to be…

  13. The NASA SCI Files[TM]: The Case of the Powerful Pulleys. A Lesson Guide with Activities in Mathematics, Science, and Technology.

    ERIC Educational Resources Information Center

    Ricles, Shannon

    This teacher's guide, with accompanying videotape, presents an episode of the NASA SCI Files. In this episode, one of the tree house detectives has had an accident and cannot get into the tree house. Using problem-based learning, the rest of the gang investigates the world of simple machines and physical science and "pull" together to…

  14. The Case of the Great Space Exploration: An Educator Guide with Activities in Mathematics, Science, and Technology. The NASA SCI Files. EG-2004-09-12-LARC

    ERIC Educational Resources Information Center

    Ricles, Shannon; Jaramillo, Becky; Fargo, Michelle

    2004-01-01

    In this companion to the "NASA SCI Files" episode "The Case of the Great Space Exploration," the tree house detectives learn about NASA's new vision for exploring space. In four segments aimed at grades 3-5, students learn about a variety of aspects of space exploration. Each segment of the guide includes an overview, a set of objectives,…

  15. Measurement of K+ production cross section by 8 GeV protons using high energy neutrino interactions in the SciBooNE detector

    DOE PAGES

    Cheng, G.

    2011-07-28

    The SciBooNE Collaboration reports K+ production cross section and rate measurements using high energy daughter muon neutrino scattering data off the SciBar polystyrene (C8H8) target in the SciBooNE detector. The K+ mesons are produced by 8 GeV protons striking a beryllium target in Fermilab Booster Neutrino Beam line (BNB). Using observed neutrino and antineutrino events in SciBooNE, we measure d2σ/dpdΩ = (5.34 ±0.76) mb/(GeV/c x sr) for p + Be =K+ + X at mean K+ energy of 3.9 GeV and angle (with respect to the proton beam direction) of 3.7 degrees, corresponding to the selected K+ sample. Compared tomore » Monte Carlo predictions using previous higher energy K+ production measurements, this measurement, which uses the NUANCE neutrino interaction generator, is consistent with a normalization factor of 0.85 ± 0.12. This agreement is evidence that the extrapolation of the higher energy K+ measurements to an 8 GeV beam energy using Feynman scaling is valid. This measurement reduces the error on the K+ production cross section from 40% to 14%.« less

  16. Measurement of K+ production cross section by 8 GeV protons using high energy neutrino interactions in the SciBooNE detector

    SciTech Connect

    Cheng, G.

    2011-07-28

    The SciBooNE Collaboration reports K+ production cross section and rate measurements using high energy daughter muon neutrino scattering data off the SciBar polystyrene (C8H8) target in the SciBooNE detector. The K+ mesons are produced by 8 GeV protons striking a beryllium target in Fermilab Booster Neutrino Beam line (BNB). Using observed neutrino and antineutrino events in SciBooNE, we measure d2σ/dpdΩ = (5.34 ±0.76) mb/(GeV/c x sr) for p + Be =K+ + X at mean K+ energy of 3.9 GeV and angle (with respect to the proton beam direction) of 3.7 degrees, corresponding to the selected K+ sample. Compared to Monte Carlo predictions using previous higher energy K+ production measurements, this measurement, which uses the NUANCE neutrino interaction generator, is consistent with a normalization factor of 0.85 ± 0.12. This agreement is evidence that the extrapolation of the higher energy K+ measurements to an 8 GeV beam energy using Feynman scaling is valid. This measurement reduces the error on the K+ production cross section from 40% to 14%.

  17. "A Ton of Faith in Science!" Nature and Role of Assumptions in, and Ideas about, Science and Epistemology Generated upon Watching a Sci-Fi Film

    ERIC Educational Resources Information Center

    Myers, John Y.; Abd-El-Khalick, Fouad

    2016-01-01

    This study (i) explicates the sorts of ideas about science and the nature of knowing that were generated among participant graduate students who viewed the sci-fi film, "Contact," and (ii) examines the interactions between these ideas and ontic stances with which participants approached viewing the film. Eleven doctoral students of…

  18. Erratum: “Multi-point, high-speed passive ion velocity distribution diagnostic on the Pegasus Toroidal Experiment” [Rev. Sci. Instrum. 83, 10D516 (2012)

    SciTech Connect

    Burke, Marcus G.; Fonck, Raymond J.; Bongard, Michael W.; Schlossberg, David J.; Winz, Gregory R.

    2016-07-18

    This article corrects an error in M.G. Burke et al., 'Multi-point, high-speed passive ion velocity distribution diagnostic on the Pegasus Toroidal Experiment,' Rev. Sci. Instrum. 83, 10D516 (2012) pertaining to ion temperature. The conclusions of this paper are not altered by the revised ion temperature measurements.

  19. Effects of Testosterone and Evoked Resistance Exercise after Spinal Cord Injury (TEREX-SCI): study protocol for a randomised controlled trial

    PubMed Central

    Gorgey, Ashraf S; Khalil, Refka E; Gill, Ranjodh; O'Brien, Laura C; Lavis, Timothy; Castillo, Teodoro; Cifu, David X; Savas, Jeannie; Khan, Rehan; Cardozo, Christopher; Lesnefsky, Edward J; Gater, David R; Adler, Robert A

    2017-01-01

    Introduction Individuals with spinal cord injury (SCI) are at a lifelong risk of obesity and chronic metabolic disorders including insulin resistance and dyslipidemia. Within a few weeks of injury, there is a significant decline in whole body fat-free mass, particularly lower extremity skeletal muscle mass, and subsequent increase in fat mass (FM). This is accompanied by a decrease in anabolic hormones including testosterone. Testosterone replacement therapy (TRT) has been shown to increase skeletal muscle mass and improve metabolic profile. Additionally, resistance training (RT) has been shown to increase lean mass and reduce metabolic disturbances in SCI and other clinical populations. Methods and analysis 26 individuals with chronic, motor complete SCI between 18 and 50 years old were randomly assigned to a RT+TRT group (n=13) or a TRT group (n=13). 22 participants completed the initial 16-week training phase of the study and 4 participants withdrew. 12 participants of the 22 completed 16 weeks of detraining. The TRT was provided via transdermal testosterone patches (4–6 mg/day). The RT+TRT group had 16 weeks of supervised unilateral progressive RT using surface neuromuscular electrical stimulation with ankle weights. This study will investigate the effects of evoked RT+TRT or TRT alone on body composition (muscle cross-sectional area, visceral adipose tissue, %FM) and metabolic profile (glucose and lipid metabolism) in individuals with motor complete SCI. Findings from this study may help in designing exercise therapies to alleviate the deterioration in body composition after SCI and decrease the incidence of metabolic disorders in this clinical population. Ethics and dissemination The study is currently approved by the McGuire VA Medical Center and Virginia Commonwealth University. All participants read and signed approved consent forms. Results will be submitted to peer-reviewed journals and presented at national and international conferences. Trial

  20. A multimethod research investigation of consumer involvement in Australian health service accreditation programmes: the ACCREDIT-SCI study protocol

    PubMed Central

    Greenfield, David; Hinchcliff, Reece; Moldovan, Max; Mumford, Virginia; Pawsey, Marjorie; Irene Westbrook, Johanna; Braithwaite, Jeffrey

    2012-01-01

    Introduction Health service accreditation programmes are a regulatory mechanism adopted to drive improvements inpatient safety and quality. Research investigating the benefits or limitations, of consumer involvement in accreditation programmes is negligible. To develop our knowledge in this area the ACCREDIT collaboration (Accreditation Collaborative for the Conduct of Research, Evaluation and Designated Investigations through Teamwork) has developed a research plan, known as the ACCREDIT-SCI (Standards of Consumer Involvement) study protocol. Two complementary studies have been designed: one, to examine the effectiveness of a standard for consumer participation and two, to explore how patient experiences vary across a range of settings with differing accreditation results. Methods and design The research setting is the Australian healthcare system, and the two studies focus on three accreditation programmes in the primary, acute and aged care domains. The studies will use multimethods: document analysis; interviews and surveys. Participants will be stakeholders across the three domains including: policy officers; frontline healthcare professionals; accreditation agency personnel, including surveyors and healthcare consumers. Drawing on previous experience, the research team has developed purpose-designed tools. Data will be analysed using thematic, narrative and statistical (descriptive and inferential) procedures. Ethics and dissemination The University of New South Wales Human Research Ethics Committee has approved the two studies (HREC 10274). Findings will be disseminated through seminars, conference presentations, academic publications and research partner websites. The findings will be formulated to facilitate uptake by policy and accreditation agency professionals, researchers and academics, and consumers, nationally and internationally. PMID:23059848

  1. Astrobites and GeoSciBites: Using Online Research Digests for Outreach to Undergraduates and the Broader Community

    NASA Astrophysics Data System (ADS)

    Ranjan, S.; Kohler, S.; Sanders, N.; Morey, S.

    2011-12-01

    Effective science communication is imperative for the sharing of scientific ideas, continued funding and support from policy makers, and education of the public. As future researchers and educators, it is particularly important to engage graduate students in science communication. Astrobites (http://astrobites.org) is an innovative education initiative developed by graduate students in planetary science, astronomy, and astrophysics. Our goal is to help undergraduates make the transition from the classroom to careers in research by introducing them to the astronomical literature in a pedagogical, approachable, and comprehensible way. Every day we select one new journal article posted to the astrophysics preprint server (arXiv.org/astro-ph) and prepare a brief summary describing methods and results, explain jargon, and provide context. We also write regular blog posts containing career advice, such as tips for applying for fellowships or demystifying the publishing process. The articles are written by 30 graduate students in astrophysics from throughout the US and Europe and are read by 1000 daily readers worldwide, including undergraduates, researchers, and interested non-scientists. We describe lessons learned in starting, sustaining, and expanding science outreach blogs like Astrobites. We survey our readership and present analysis summarizing our reader base and impact. We report on the foundation of other ';bites blogs, focusing on the foundation of GeoSciBites, a geophysical sciences outreach blog. We discuss future opportunities for additional outreach initiatives in new disciplines.

  2. Evaluation of university scientific research ability based on the output of sci-tech papers: A D-AHP approach

    PubMed Central

    Wang, Lifang

    2017-01-01

    University scientific research ability is an important indicator to express the strength of universities. In this paper, the evaluation of university scientific research ability is investigated based on the output of sci-tech papers. Four university alliances from North America, UK, Australia, and China, are selected as the case study of the university scientific research evaluation. Data coming from Thomson Reuters InCites are collected to support the evaluation. The work has contributed new framework to the issue of university scientific research ability evaluation. At first, we have established a hierarchical structure to show the factors that impact the evaluation of university scientific research ability. Then, a new MCDM method called D-AHP model is used to implement the evaluation and ranking of different university alliances, in which a data-driven approach is proposed to automatically generate the D numbers preference relations. Next, a sensitivity analysis has been given to show the impact of weights of factors and sub-factors on the evaluation result. At last, the results obtained by using different methods are compared and discussed to verify the effectiveness and reasonability of this study, and some suggestions are given to promote China’s scientific research ability. PMID:28212446

  3. Astrobites and GeoSciBites: Using Online Research Digests for Outreach to Undergraduates and the Broader Community

    NASA Astrophysics Data System (ADS)

    Ranjan, S.; Kohler, S.; Sanders, N.; Morey, S.

    2013-12-01

    Effective science communication is imperative for the sharing of scientific ideas, continued funding and support from policy makers, and education of the public. As future researchers and educators, it is particularly important to engage graduate students in science communication. Astrobites (http://astrobites.org) is an innovative education initiative developed by graduate students in planetary science, astronomy, and astrophysics. Our goal is to help undergraduates make the transition from the classroom to careers in research by introducing them to the astronomical literature in a pedagogical, approachable, and comprehensible way. Every day we select one new journal article posted to the astrophysics preprint server (arXiv.org/astro-ph) and prepare a brief summary describing methods and results, explain jargon, and provide context. We also write regular blog posts containing career advice, such as tips for applying for fellowships or demystifying the publishing process. The articles are written by 30 graduate students in astrophysics from throughout the US and Europe and are read by 1000 daily readers worldwide, including undergraduates, researchers, and interested non-scientists. We describe lessons learned in starting, sustaining, and expanding science outreach blogs like Astrobites. We survey our readership and present analysis summarizing our reader base and impact. We report on the foundation of other ';bites blogs, focusing on the foundation of GeoSciBites, a geophysical sciences outreach blog. We discuss future opportunities for additional outreach initiatives in new disciplines.

  4. Twenty years of Internet-based research at SCiP: A discussion of surviving concepts and new methodologies.

    PubMed

    Wolfe, Christopher R

    2017-02-07

    This discussion of the symposium 20 Years of Internet-Based Research at SCiP: Surviving Concepts, New Methodologies compares the issues faced by the pioneering Internet-based psychology researchers who presented at the first symposia on the topic, at the 1996 annual meeting of the Society for Computers in Psychology, to the issues facing researchers today. New methodologies unavailable in the early days of Web-based psychological research are discussed, with an emphasis on mobile computing with smartphones that is capitalizing on capabilities such as touch screens and gyro sensors. A persistent issue spanning the decades has been the challenge of conducting scientific research with consumer-grade electronics. In the 1996 symposia on Internet-based research, four advantages were identified: easy access to a geographically unlimited subject population, including subjects from very specific and previously inaccessible target populations; bringing the experiment to the subject; high statistical power through large sample size; and reduced cost. In retrospect, it appears that Internet-based research has largely lived up to this early promise-with the possible exception of sample size, since the public demand for controlled psychology experiments has not always been greater than the supply offered by researchers. There are many reasons for optimism about the future of Internet-based research. However, unless courses and textbooks on psychological research methods begin to give Web-based research the attention it deserves, the future of Internet-based psychological research will remain in doubt.

  5. ReSciPE for Scientific Inquiry: Professional Development for Scientists to Support Their Work With Education

    NASA Astrophysics Data System (ADS)

    Smith, L. K.; Laursen, S.; Schott, C.

    2006-12-01

    Funders and institutions are asking scientists to become more involved in communicating the "broader impacts" of their work with the public. Many scientists also wish to contribute to public science literacy and high-quality science education in schools. The ReSciPE Project--Resources for Scientists in Partnership with Education--is providing professional development workshops and other resources to scientists who are involved in education as volunteers or through professional commitments. As of fall 2006, we have presented 16 workshops on "Scientific Inquiry in the K-12 Classroom" to over 350 scientists and science educators at professional meetings, laboratories, and universities from Massachusetts to Hawaii. We will describe the project goals and our model for helping scientists to become more effective in working with students and teachers. Evaluation results from pre- and post-workshop surveys of over 200 workshop participants demonstrate that we are reaching an audience of working scientists as well as science educators and E/PO specialists, that our audience is diverse in gender, ethnicity, and career stage, and that the workshops are effective in broadening participants' ideas of their potential role in education. However, they also have ongoing needs for both knowledge and support. We argue that working with education or other public audiences is an increasingly important professional skill for scientists and offer this project as one experiment in providing appropriate professional development for this work.

  6. Evaluation of university scientific research ability based on the output of sci-tech papers: A D-AHP approach.

    PubMed

    Zong, Fan; Wang, Lifang

    2017-01-01

    University scientific research ability is an important indicator to express the strength of universities. In this paper, the evaluation of university scientific research ability is investigated based on the output of sci-tech papers. Four university alliances from North America, UK, Australia, and China, are selected as the case study of the university scientific research evaluation. Data coming from Thomson Reuters InCites are collected to support the evaluation. The work has contributed new framework to the issue of university scientific research ability evaluation. At first, we have established a hierarchical structure to show the factors that impact the evaluation of university scientific research ability. Then, a new MCDM method called D-AHP model is used to implement the evaluation and ranking of different university alliances, in which a data-driven approach is proposed to automatically generate the D numbers preference relations. Next, a sensitivity analysis has been given to show the impact of weights of factors and sub-factors on the evaluation result. At last, the results obtained by using different methods are compared and discussed to verify the effectiveness and reasonability of this study, and some suggestions are given to promote China's scientific research ability.

  7. Sci-Fi Science.

    ERIC Educational Resources Information Center

    Freudenrich, Craig C.

    2000-01-01

    Recommends using science fiction television episodes, novels, and films for teaching science and motivating students. Studies Newton's Law of Motion, principles of relativity, journey to Mars, interplanetary trajectories, artificial gravity, and Martian geology. Discusses science fiction's ability to capture student interest and the advantages of…

  8. Sci-Vis Framework

    SciTech Connect

    Arthur Bleeker, PNNL

    2015-03-11

    SVF is a full featured OpenGL 3d framework that allows for rapid creation of complex visualizations. The SVF framework handles much of the lifecycle and complex tasks required for a 3d visualization. Unlike a game framework SVF was designed to use fewer resources, work well in a windowed environment, and only render when necessary. The scene also takes advantage of multiple threads to free up the UI thread as much as possible. Shapes (actors) in the scene are created by adding or removing functionality (through support objects) during runtime. This allows a highly flexible and dynamic means of creating highly complex actors without the code complexity (it also helps overcome the lack of multiple inheritance in Java.) All classes are highly customizable and there are abstract classes which are intended to be subclassed to allow a developer to create more complex and highly performant actors. There are multiple demos included in the framework to help the developer get started and shows off nearly all of the functionality. Some simple shapes (actors) are already created for you such as text, bordered text, radial text, text area, complex paths, NURBS paths, cube, disk, grid, plane, geometric shapes, and volumetric area. It also comes with various camera types for viewing that can be dragged, zoomed, and rotated. Picking or selecting items in the scene can be accomplished in various ways depending on your needs (raycasting or color picking.) The framework currently has functionality for tooltips, animation, actor pools, color gradients, 2d physics, text, 1d/2d/3d textures, children, blending, clipping planes, view frustum culling, custom shaders, and custom actor states

  9. Basics of SCI Rehabilitation

    MedlinePlus Videos and Cool Tools

    ... Question Videos by Family Relationship Videos by Experts Resources The Short List Government Programs Family and Caregiver ... by Family Relationship Videos by Spinal Cord Experts Resources Forums Peer Counseling Blog About Us Contact Donate ...

  10. Preface for Atmos. Env. Special issue on IBBI

    NASA Astrophysics Data System (ADS)

    Kaiser, Johannes W.; Keywood, Melita

    2015-11-01

    The first vegetation fires, or biomass burning, occurred shortly after the emergence of land vegetation around 400 million years ago. Biomass burning is now an integral part of many natural and human-influenced ecosystems with fires being widespread on all continents except Antarctica. They are ignited both naturally (lightning, volcanoes) and by human activities. Their subsequent spread is influenced by various factors including climate, meteorology, and the state of the vegetation as well as human activities including agricultural and suppression practises. Smoke from biomass burning constitutes a major source of trace gases and aerosols that effect atmospheric chemistry, radiative processes and cloud formation, influencing climate, human health and security. Advances in the space-based observation of open vegetation fires have lead to great innovation in quantifying fire emissions over the last 15 years as new sensors and retrieval techniques open new opportunities to derive more accurate information on fire occurrence, behaviour, severity and impacts. In addition a number of satellite-based observation capabilities of the atmospheric composition of smoke plumes have been implemented while fire and atmospheric modelling capabilities have greatly improved and cover scales from chemical reactions to global long-range transport. Operational forecasting systems based on the observation and models now provide real time guidance to emergency, environmental and health services related to fire spread and air quality. Furthermore, climate models include more detailed vegetation models and their interactions with fire regimes. Nevertheless, large uncertainties in the quantification of fire properties and emissions remain.

  11. Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis.

    PubMed

    Wring, Stephen A; Randolph, Ryan; Park, SeongHee; Abruzzo, George; Chen, Qing; Flattery, Amy; Garrett, Graig; Peel, Michael; Outcalt, Russell; Powell, Kendall; Trucksis, Michelle; Angulo, David; Borroto-Esoda, Katyna

    2017-04-01

    SCY-078 (MK-3118) is a novel, semisynthetic derivative of enfumafungin and represents the first compound of the triterpene class of antifungals. SCY-078 exhibits potent inhibition of β-(1,3)-d-glucan synthesis, an essential cell wall component of many pathogenic fungi, including Candida spp. and Aspergillus spp. SCY-078 is currently in phase 2 clinical development for the treatment of invasive fungal diseases. In vitro disposition studies to assess solubility, intestinal permeability, and metabolic stability were predictive of good oral bioavailability. Preclinical pharmacokinetic studies were consistent with once-daily administration to humans. After intravenous delivery, plasma clearance in rodents and dogs was low, representing <15% and <25% of hepatic blood flow, respectively. The terminal elimination-phase half-life was 5.5 to 8.7 h in rodents, and it was ∼9.3 h in dogs. The volume of distribution at steady-state was high (4.7 to 5.3 liters/kg), a finding suggestive of extensive tissue distribution. Exposure of SCY-078 in kidney tissue, a target organ for invasive fungal disease such as candidiasis, exceeded plasma by 20- to 25-fold for the area under the concentration-time curve from 0 h to infinity (AUC0-∞) and Cmax SCY-078 achieved efficacy endpoints following oral delivery across multiple murine models of disseminated candidiasis. The pharmacokinetic/pharmacodynamic indices Cmax/MIC and AUC/MIC correlated with outcome. Target therapeutic exposure, expressed as the plasma AUC0-24, was comparable across models, with an upper value of 11.2 μg·h/ml (15.4 μM·h); the corresponding mean value for free drug AUC/MIC was ∼0.75. Overall, these results demonstrate that SCY-078 has the oral and intravenous (i.v.) pharmacokinetic properties and potency in murine infection models of disseminated candidiasis to support further investigation as a novel i.v. and oral treatment for invasive fungal diseases.

  12. Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis

    PubMed Central

    Randolph, Ryan; Park, SeongHee; Abruzzo, George; Chen, Qing; Flattery, Amy; Garrett, Graig; Peel, Michael; Outcalt, Russell; Powell, Kendall; Trucksis, Michelle; Angulo, David; Borroto-Esoda, Katyna

    2017-01-01

    ABSTRACT SCY-078 (MK-3118) is a novel, semisynthetic derivative of enfumafungin and represents the first compound of the triterpene class of antifungals. SCY-078 exhibits potent inhibition of β-(1,3)-d-glucan synthesis, an essential cell wall component of many pathogenic fungi, including Candida spp. and Aspergillus spp. SCY-078 is currently in phase 2 clinical development for the treatment of invasive fungal diseases. In vitro disposition studies to assess solubility, intestinal permeability, and metabolic stability were predictive of good oral bioavailability. Preclinical pharmacokinetic studies were consistent with once-daily administration to humans. After intravenous delivery, plasma clearance in rodents and dogs was low, representing <15% and <25% of hepatic blood flow, respectively. The terminal elimination-phase half-life was 5.5 to 8.7 h in rodents, and it was ∼9.3 h in dogs. The volume of distribution at steady-state was high (4.7 to 5.3 liters/kg), a finding suggestive of extensive tissue distribution. Exposure of SCY-078 in kidney tissue, a target organ for invasive fungal disease such as candidiasis, exceeded plasma by 20- to 25-fold for the area under the concentration-time curve from 0 h to infinity (AUC0–∞) and Cmax. SCY-078 achieved efficacy endpoints following oral delivery across multiple murine models of disseminated candidiasis. The pharmacokinetic/pharmacodynamic indices Cmax/MIC and AUC/MIC correlated with outcome. Target therapeutic exposure, expressed as the plasma AUC0–24, was comparable across models, with an upper value of 11.2 μg·h/ml (15.4 μM·h); the corresponding mean value for free drug AUC/MIC was ∼0.75. Overall, these results demonstrate that SCY-078 has the oral and intravenous (i.v.) pharmacokinetic properties and potency in murine infection models of disseminated candidiasis to support further investigation as a novel i.v. and oral treatment for invasive fungal diseases. PMID:28137806

  13. Ontological Encoding of GeoSciML and INSPIRE geological standard vocabularies and schemas: application to geological mapping

    NASA Astrophysics Data System (ADS)

    Lombardo, Vincenzo; Piana, Fabrizio; Mimmo, Dario; Fubelli, Giandomenico; Giardino, Marco

    2016-04-01

    Encoding of geologic knowledge in formal languages is an ambitious task, aiming at the interoperability and organic representation of geological data, and semantic characterization of geologic maps. Initiatives such as GeoScience Markup Language (last version is GeoSciML 4, 2015[1]) and INSPIRE "Data Specification on Geology" (an operative simplification of GeoSciML, last version is 3.0 rc3, 2013[2]), as well as the recent terminological shepherding of the Geoscience Terminology Working Group (GTWG[3]) have been promoting information exchange of the geologic knowledge. There have also been limited attempts to encode the knowledge in a machine-readable format, especially in the lithology domain (see e.g. the CGI_Lithology ontology[4]), but a comprehensive ontological model that connect the several knowledge sources is still lacking. This presentation concerns the "OntoGeonous" initiative, which aims at encoding the geologic knowledge, as expressed through the standard vocabularies, schemas and data models mentioned above, through a number of interlinked computational ontologies, based on the languages of the Semantic Web and the paradigm of Linked Open Data. The initiative proceeds in parallel with a concrete case study, concerning the setting up of a synthetic digital geological map of the Piemonte region (NW Italy), named "GEOPiemonteMap" (developed by the CNR Institute of Geosciences and Earth Resources, CNR IGG, Torino), where the description and classification of GeologicUnits has been supported by the modeling and implementation of the ontologies. We have devised a tripartite ontological model called OntoGeonous that consists of: 1) an ontology of the geologic features (in particular, GeologicUnit, GeomorphologicFeature, and GeologicStructure[5], modeled from the definitions and UML schemata of CGI vocabularies[6], GeoScienceML and INSPIRE, and aligned with the Planetary realm of NASA SWEET ontology[7]), 2) an ontology of the Earth materials (as defined by the

  14. SciDAC's Earth System Grid Center for Enabling Technologies Semiannual Progress Report October 1, 2010 through March 31, 2011

    SciTech Connect

    Williams, Dean N.

    2011-04-02

    This report summarizes work carried out by the Earth System Grid Center for Enabling Technologies (ESG-CET) from October 1, 2010 through March 31, 2011. It discusses ESG-CET highlights for the reporting period, overall progress, period goals, and collaborations, and lists papers and presentations. To learn more about our project and to find previous reports, please visit the ESG-CET Web sites: http://esg-pcmdi.llnl.gov/ and/or https://wiki.ucar.edu/display/esgcet/Home. This report will be forwarded to managers in the Department of Energy (DOE) Scientific Discovery through Advanced Computing (SciDAC) program and the Office of Biological and Environmental Research (OBER), as well as national and international collaborators and stakeholders (e.g., those involved in the Coupled Model Intercomparison Project, phase 5 (CMIP5) for the Intergovernmental Panel on Climate Change (IPCC) 5th Assessment Report (AR5); the Community Earth System Model (CESM); the Climate Science Computational End Station (CCES); SciDAC II: A Scalable and Extensible Earth System Model for Climate Change Science; the North American Regional Climate Change Assessment Program (NARCCAP); the Atmospheric Radiation Measurement (ARM) program; the National Aeronautics and Space Administration (NASA), the National Oceanic and Atmospheric Administration (NOAA)), and also to researchers working on a variety of other climate model and observation evaluation activities. The ESG-CET executive committee consists of Dean N. Williams, Lawrence Livermore National Laboratory (LLNL); Ian Foster, Argonne National Laboratory (ANL); and Don Middleton, National Center for Atmospheric Research (NCAR). The ESG-CET team is a group of researchers and scientists with diverse domain knowledge, whose home institutions include eight laboratories and two universities: ANL, Los Alamos National Laboratory (LANL), Lawrence Berkeley National Laboratory (LBNL), LLNL, NASA/Jet Propulsion Laboratory (JPL), NCAR, Oak Ridge National

  15. Results of a Telephone Survey of Television Station Managers Concerning the NASA SCI Files(TM) and NASA CONNECT(TM)

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Perry, Jeannine

    2004-01-01

    A telephone survey of television station managers concerning 2 instructional television programs, the NASA SCI Files(TM) and NASA CONNECT(TM), offered by the NASA Langley Center for Distance Learning (CDL) was conducted. Using a 4-point scale, with 4 being very satisfied, survey participants reported that they were either very satisfied (77.1 percent) or satisfied (19.9 percent) with the overall (educational and technical) quality of the NASA SCI Files(TM). Using a 4-point scale, with 4 being very satisfied, survey participants reported that they were either very satisfied (77.9 percent) or satisfied (19.1 percent) with the overall (educational and technical) quality of NASA CONNECT(TM) .

  16. SciDAC's Earth System Grid Center for Enabling Technologies Semi-Annual Progress Report for the Period October 1, 2009 through March 31, 2010

    SciTech Connect

    Williams, Dean N.; Foster, I. T.; Middleton, D. E.; Ananthakrishnan, R.; Siebenlist, F.; Shoshani, A.; Sim, A.; Bell, G.; Drach, R.; Ahrens, J.; Jones, P.; Brown, D.; Chastang, J.; Cinquini, L.; Fox, P.; Harper, D.; Hook, N.; Nienhouse, E.; Strand, G.; West, P.; Wilcox, H.; Wilhelmi, N.; Zednik, S.; Hankin, S.; Schweitzer, R.; Bernholdt, D.; Chen, M.; Miller, R.; Shipman, G.; Wang, F.; Bharathi, S.; Chervenak, A.; Schuler, R.; Su, M.

    2010-04-21

    This report summarizes work carried out by the ESG-CET during the period October 1, 2009 through March 31, 2009. It includes discussion of highlights, overall progress, period goals, collaborations, papers, and presentations. To learn more about our project, and to find previous reports, please visit the Earth System Grid Center for Enabling Technologies (ESG-CET) website. This report will be forwarded to the DOE SciDAC program management, the Office of Biological and Environmental Research (OBER) program management, national and international collaborators and stakeholders (e.g., the Community Climate System Model (CCSM), the Intergovernmental Panel on Climate Change (IPCC) 5th Assessment Report (AR5), the Climate Science Computational End Station (CCES), the SciDAC II: A Scalable and Extensible Earth System Model for Climate Change Science, the North American Regional Climate Change Assessment Program (NARCCAP), and other wide-ranging climate model evaluation activities).

  17. Measuring grief and loss after spinal cord injury: Development, validation and psychometric characteristics of the SCI-QOL Grief and Loss item bank and short form

    PubMed Central

    Kalpakjian, Claire Z.; Tulsky, David S.; Kisala, Pamela A.; Bombardier, Charles H.

    2015-01-01

    Objective To develop an item response theory (IRT) calibrated Grief and Loss item bank as part of the Spinal Cord Injury – Quality of Life (SCI-QOL) measurement system. Design A literature review guided framework development of grief/loss. New items were created from focus groups. Items were revised based on expert review and patient feedback and were then field tested. Analyses included confirmatory factor analysis (CFA), graded response IRT modeling and evaluation of differential item functioning (DIF). Setting We tested a 20-item pool at several rehabilitation centers across the United States, including the University of Michigan, Kessler Foundation, Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital and the James J. Peters/Bronx Department of Veterans Affairs hospital. Participants A total of 717 individuals with SCI answered the grief and loss questions. Results The final calibrated item bank resulted in 17 retained items. A unidimensional model was observed (CFI = 0.976; RMSEA = 0.078) and measurement precision was good (theta range between −1.48 to 2.48). Ten items were flagged for DIF, however, after examination of effect sizes found this to be negligible with little practical impact on score estimates. Conclusions This study indicates that the SCI-QOL Grief and Loss item bank represents a psychometrically robust measurement tool. Short form items are also suggested and computer adaptive tests are available. PMID:26010969

  18. Measuring psychological trauma after spinal cord injury: Development and psychometric characteristics of the SCI-QOL Psychological Trauma item bank and short form

    PubMed Central

    Kisala, Pamela A.; Victorson, David; Pace, Natalie; Heinemann, Allen W.; Choi, Seung W.; Tulsky, David S.

    2015-01-01

    Objective To describe the development and psychometric properties of the SCI-QOL Psychological Trauma item bank and short form. Design Using a mixed-methods design, we developed and tested a Psychological Trauma item bank with patient and provider focus groups, cognitive interviews, and item response theory based analytic approaches, including tests of model fit, differential item functioning (DIF) and precision. Setting We tested a 31-item pool at several medical institutions across the United States, including the University of Michigan, Kessler Foundation, Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital and the James J. Peters/Bronx Veterans Administration hospital. Participants A total of 716 individuals with SCI completed the trauma items Results The 31 items fit a unidimensional model (CFI=0.952; RMSEA=0.061) and demonstrated good precision (theta range between 0.6 and 2.5). Nine items demonstrated negligible DIF with little impact on score estimates. The final calibrated item bank contains 19 items Conclusion The SCI-QOL Psychological Trauma item bank is a psychometrically robust measurement tool from which a short form and a computer adaptive test (CAT) version are available. PMID:26010967

  19. Product and market study for Los Alamos National Laboratory. Building resources for technology commercialization: The SciBus Analytical, Inc. paradigm

    SciTech Connect

    1996-02-01

    The study project was undertaken to investigate how entrepreneurial small businesses with technology licenses can develop product and market strategies sufficiently persuasive to attract resources and exploit commercialization opportunities. The study attempts to answer two primary questions: (1) What key business development strategies are likely to make technology transfers successful, and (2) How should the plan best be presented in order to attract resources (e.g., personnel, funding, channels of distribution)? In the opinion of the investigator, Calidex Corporation, if the business strategies later prove to be successful, then the plan model has relevance for any technology licensee attempting to accumulate resources and bridge from technology resident in government laboratories to the commercial marketplace. The study utilized SciBus Analytical, Inc. (SciBus), a Los Alamos National Laboratory CRADA participant, as the paradigm small business technology licensee. The investigator concluded that the optimum value of the study lay in the preparation of an actual business development plan for SciBus that might then have, hopefully, broader relevance and merit for other private sector technology transfer licensees working with various Government agencies.

  20. The psychometric properties of Chinese version of SCI Exercise Self-Efficacy Scale in patients with stroke

    PubMed Central

    Dong, Xiaofang; Liu, Yanjin; Wang, Aixia; Wang, Min

    2016-01-01

    Objective To test the Chinese version of the SCI Exercise Self-Efficacy Scale (C-ESES) in stroke patients and evaluate its validity and reliability. Background Physical inactivity is a well established and changeable risk factor for stroke, and regular exercise of 3–7 days per week is essential for stroke survivors and the general population. Though regular exercise is beneficial, it has been proved that duration, frequency, and intensity of exercise are generally low in stroke survivors. Methods The performance of the instrument was assessed in 350 Chinese stroke survivors and repeated in 50 patients to examine test–retest reliability. Questionnaires included a form on demographic and socioeconomic characteristics, C-ESES, and the Chinese version of the General Self-Efficacy Scale. The AMOS 20.0 and SPSS 17.0 were chosen to evaluate their validity and reliability. Results Even though 350 participants answered the questionnaires in the present study, useful data were obtained from 321 participants (response rate: 91.71%). Correlation between item and the total scale score (Item–Total Correlation) ranged from 0.551 to 0.718, indicating that no item needed to be omitted; two factors, with factor loading 0.620 and 0.806, were obtained from an exploratory principal components analysis, assuming 59.745% of the total variance. The two factors were named internal motivation and external motivation. A confirmatory factor analysis supported the results with a suitable model (χ5=291.157; df=185; P<0.001; root mean square error of approximation =0.044; goodness-of-fit index =0.938; adjusted goodness-of-fit index =0.914; comparative fit index =0.858). The C-ESES correlated well with the validated General Self-Efficacy Scale (r=0.827, P<0.01). Good internal consistency (Cronbach’s α=0.757 to 0.879) and test–retest reliability (r=0.750, P<0.01) were obtained. Conclusion The C-ESES is a short, easy to understand, and psychometrically sound measurement to evaluate

  1. Final Report on DOE SciDAC project on Next Generation of Multi-Scale Quantum Simulation Software for Strongly Correlated Materials

    SciTech Connect

    Bai, Zhaojun; Scalettar, Richard; Savrasov, Sergey

    2012-07-01

    This report summarizes the accomplishments of the University of California Davis team which is part of a larger SciDAC collaboration including Mark Jarrell of Louisiana State University, Karen Tomko of the Ohio Supercomputer Center, and Eduardo F. D'Azevedo and Thomas A. Maier of Oak Ridge National Laboratory. In this report, we focus on the major UCD accomplishments. As the paper authorship list emphasizes, much of our work is the result of a tightly integrated effort; hence this compendium of UCD efforts of necessity contains some overlap with the work at our partner institutions.

  2. Building Infrastructure to Accelerate Transfer of Basic Research in Spinal Cord Injury (SCI) to Clinical Practice: North American Clinical Trials Network

    DTIC Science & Technology

    2013-08-01

    Association for Collaborative Spine Research annual meeting in Chicago at the end of July and they will meet separately to decide how best to move forward with...Mild and moderate elevation of ALT and AST in SCI patients, as reported by Shepard and Bracken,23 was confirmed to occur within the first day of...Spine (Suppl.) 17, 119–128. 23. Shepard , M.J., and Bracken, M.B. (1994). The effect of methyl- prednisilone, naloxone, and spinal cord trauma on

  3. Comment on ``Implementing of a precision fast thermoelectric cooler using a personal computer parallel port connection and ADN8830 controller'' [Rev. Sci. Instrum. 74, 3862 (2003)

    NASA Astrophysics Data System (ADS)

    Sloman, A. W.

    2004-03-01

    Eli Flaxer has described a feedback controlled circuit to drive a Peltier junction to control the temperature of a specimen in the range 0 to 50 °C in a room temperature environment [Rev. Sci. Instrum. 74, 3862 (2003)]. The amount of heat transferred per unit current by a Peltier junction varies substantially with the temperature difference across the Peltier junction. Flaxer's circuit does not provide any mechanism to compensate for this variation. This means that if the proportional-integral-differential control loop he uses is optimized at any particular temperature differential, the control loop with be over-damped at lower specimen temperatures, and under-damped at higher specimen temperatures. A circuit using a second thermistor to monitor the temperature of the exhaust side of the Peltier junction, and a digital control loop, can minimize this problem [A. W. Sloman, Paul Buggs, James Molloy, and Douglas Stewart, Meas. Sci. Technol. 7, 1653 (1996)]. This circuit has the incidental advantage of offering ten times better temperature stability.

  4. Final Report for "Tech-X Corporation work for the SciDAC Center for Simulation of RF Wave Interactions with Magnetohydrodynamics (SWIM)"

    SciTech Connect

    Jenkins, Thomas G.; Kruger, Scott E.

    2013-03-25

    Work carried out by Tech-X Corporation for the DoE SciDAC Center for Simulation of RF Wave Interactions with Magnetohydrodynamics (SWIM; U.S. DoE Office of Science Award Number DE-FC02-06ER54899) is summarized and is shown to fulfil the project objectives. The Tech-X portion of the SWIM work focused on the development of analytic and computational approaches to study neoclassical tearing modes and their interaction with injected electron cyclotron current drive. Using formalism developed by Hegna, Callen, and Ramos [Phys. Plasmas 16, 112501 (2009); Phys. Plasmas 17, 082502 (2010); Phys. Plasmas 18, 102506 (2011)], analytic approximations for the RF interaction were derived and the numerical methods needed to implement these interactions in the NIMROD extended MHD code were developed. Using the SWIM IPS framework, NIMROD has successfully coupled to GENRAY, an RF ray tracing code; additionally, a numerical control system to trigger the RF injection, adjustment, and shutdown in response to tearing mode activity has been developed. We discuss these accomplishments, as well as prospects for ongoing future research that this work has enabled (which continue in a limited fashion under the SciDAC Center for Extended Magnetohydrodynamic Modeling (CEMM) project and under a baseline theory grant). Associated conference presentations, published articles, and publications in progress are also listed.

  5. Anti-preS responses influence the anti-HBs response in newborns after vaccination with the third generation Sci-B-Vac vaccine.

    PubMed

    Sylvan, Staffan P E; Madalinski, Kazimierz; Hellström, Ulla B

    2009-12-11

    We analysed the specificity and significance of the antibody response towards the linear preS1 sequence that has been shown to represent the "hepatocyte binding site" comprising amino acids preS1 (21-47) or the specific preS2 (131-140) antibody response to the "polymerised albumin receptor" in relation to the antibody response to hepatitis B surface antigen during immunisation of healthy children with the preS-containing Sci-B-Vac vaccine. Twenty-eight healthy newborns received three doses of the Sci-B-Vac vaccine according to a 0-, 1-, and 6-month scheme. Seventeen (61%) of the 28 newborns had detectable levels of anti-preS1 (21-47) antibodies and 14 (50%) were anti-preS2 (131-140) reactive at 6 and/or 9 months after initiation of the vaccination. The mean levels of anti-HBs were significantly higher in the anti-preS2 (131-140) non-reactive (24580+/-7815IU/l, mean+SEM) compared with the reactive sera (7287+/-2317IU/l, p<0.025). The highest anti-HBs levels were found in newborns who exhibited reactivity towards the aa 21-47 of the preS1 but lacked anti-preS2 (131-140) reactivity.

  6. Sterilization-CO2-Injection (SCI) BaPS: Establishment of a new method to measure rates of soil respiration and gross nitrification in calcareous agricultural soils

    NASA Astrophysics Data System (ADS)

    Conrads, Hannah; Ingwersen, Joachim; Streck, Thilo

    2013-04-01

    Soil respiration and nitrification are key processes in carbon and nitrogen cycling in soil. An exact measurement of these two processes is a prerequisite for understanding the release of trace gases from soils. During the last decades the Barometric Process Separation (BaPS) method has become a widely used method to measure the turnover rates of these two processes. Its application, however, is currently limited to acidic to slightly acidic soils. In calcareous soils huge amounts of CO2 from soil respiration are dissolved in the soil solution, and the application of the BaPS method is hampered by the exact quantification of this flux. Small errors in this flux may result in huge errors in the calculation of the nitrification and respiration rates. In order to overcome this shortcoming and to extend the applicability of the method to a wider range of soils (especially agricultural soils) we developed a new adaptive method, the Sterilization-CO2-Injection (SCI) method, which aims to determine the CO2 dissolution flux (CO2,aq) experimentally. Therefore, an additional measuring step is introduced in which a sterilized soil subsample is incubated in the BaPS apparatus and known amounts of a pure CO2 gas are injected into the system while CO2 partial pressure is monitored. After each injection peak CO2 partial pressure decreases until a new stable equilibrium concentration is reached. This behavior is used to compute the amount of CO2 transferred to the soil solution applying simple mass balance calculation. The paired information about CO2 and CO2,aq is used to derive a regression equation, which gives CO2,aq as a function of the CO2 partial pressure. This relation is further used within the standard BaPS method. Results of the SCI-BaPS method for gross nitrification rates will be presented and compared to data measured by the 15N pool dilution method (Kirkham and Bartholomew, 1954). Results were obtained with calcareous and acidic agricultural soil samples. It turned

  7. [Comparison and thinking on literatures of low back pain treated with acupuncture-moxibustion published in foreign SCI journals and domestic core journals].

    PubMed

    Lin, Xiang-Jun; Li, Rui

    2012-07-01

    The literatures of clinical research on acupuncture treatment of low back pain included in foreign SCI journals as well as the domestic core journals in the recent 10 years were collected in this article to discuss the divergence of views domestically and abroad. The result showed that acute and chronic back pain and low back pain were generally set as the targets of research abroad. While, diseases with western diagnosis such as lumbar disc herniation was often set as the study target by domestic researchers. It indicats that divergence existed in understanding and study methods between Chinese and foreign research fellows. Thus, comparison should be carried out so as to learn from the strong points of each other and close the gap.

  8. panMetaDocs, eSciDoc, and DOIDB - an infrastructure for the curation and publication of file-based datasets for 'GFZ Data Services'

    NASA Astrophysics Data System (ADS)

    Ulbricht, Damian; Elger, Kirsten; Bertelmann, Roland; Klump, Jens

    2016-04-01

    With the foundation of DataCite in 2009 and the technical infrastructure installed in the last six years it has become very easy to create citable dataset DOIs. Nowadays, dataset DOIs are increasingly accepted and required by journals in reference lists of manuscripts. In addition, DataCite provides usage statistics [1] of assigned DOIs and offers a public search API to make research data count. By linking related information to the data, they become more useful for future generations of scientists. For this purpose, several identifier systems, as ISBN for books, ISSN for journals, DOI for articles or related data, Orcid for authors, and IGSN for physical samples can be attached to DOIs using the DataCite metadata schema [2]. While these are good preconditions to publish data, free and open solutions that help with the curation of data, the publication of research data, and the assignment of DOIs in one software seem to be rare. At GFZ Potsdam we built a modular software stack that is made of several free and open software solutions and we established 'GFZ Data Services'. 'GFZ Data Services' provides storage, a metadata editor for publication and a facility to moderate minted DOIs. All software solutions are connected through web APIs, which makes it possible to reuse and integrate established software. Core component of 'GFZ Data Services' is an eSciDoc [3] middleware that is used as central storage, and has been designed along the OAIS reference model for digital preservation. Thus, data are stored in self-contained packages that are made of binary file-based data and XML-based metadata. The eSciDoc infrastructure provides access control to data and it is able to handle half-open datasets, which is useful in embargo situations when a subset of the research data are released after an adequate period. The data exchange platform panMetaDocs [4] makes use of eSciDoc's REST API to upload file-based data into eSciDoc and uses a metadata editor [5] to annotate the files

  9. Comment on Neiser et al. Assessment of Dextran Antigenicity of Intravenous Iron Preparations with Enzyme-Linked Immunosorbent Assay (ELISA). Int. J. Mol. Sci. 2016, 17, 1185.

    PubMed

    Strom, Claes C; Andreasen, Hans B

    2017-01-10

    All IV iron complexes carry a risk of potentially fatal allergic type hypersensitivity reactions. The mechanism(s) behind these reactions is unknown but the limited data available suggests that classic IgE mediated allergy is exceedingly rare, if ever occurring. Iron-carbohydrate molecules are complex nano-particles and trying to reduce the risk of serious hypersensitivity to antibody binding of an artificial antibody seems meaningless. A recently published analysis of safety data from randomized clinical trials confirms the method reported by Neiser to be useless to predict reaction risk. In conclusion, the study by Neiser et al. is biased, contains no new information, and has no clinical relevance. We are concerned that the association of the authors with a commercial entity has caused a conflict of interest that biases not only the results, but the entire experimental setup against competitors. (Comment on Neiser et al. Int. J. Mol. Sci. 2016, 17, 1185, doi:10.3390/ijms17071185).

  10. PROBING THE DARK AGES AT z ∼ 20: THE SCI-HI 21 cm ALL-SKY SPECTRUM EXPERIMENT

    SciTech Connect

    Voytek, Tabitha C.; Natarajan, Aravind; Peterson, Jeffrey B.; Jáuregui García, José Miguel; López-Cruz, Omar

    2014-02-10

    We present first results from the SCI-HI experiment, which we used to measure the all-sky-averaged 21 cm brightness temperature in the redshift range 14.8 < z < 22.7. The instrument consists of a single broadband sub-wavelength size antenna and a sampling system for real-time data processing and recording. Preliminary observations were completed in 2013 June at Isla Guadalupe, a Mexican biosphere reserve located in the Pacific Ocean. The data was cleaned to excise channels contaminated by radio frequency interference, and the system response was calibrated by comparing the measured brightness temperature to the Global Sky Model of the Galaxy and by independent measurement of Johnson noise from a calibration terminator. We present our results, discuss the cosmological implications, and describe plans for future work.

  11. Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal – a case study from health science

    PubMed Central

    Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

    2016-01-01

    Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case with publications from the health sciences. We evaluate the matching process based on information about coverage, precision, and characteristics of publications matched versus not matched with UIDs as the match keys. We analyze this information to detect errors, if any, in the matching process. As an example we also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication.  The objective is addressed in a literature review and a case study. The literature review shows that only a few studies evaluate how well UIDs work as a match key. From the literature we identify four error types: Duplicate digital object identifiers (DOI), incorrect DOIs in reference lists and databases, DOIs not registered by the database where a bibliometric analysis is performed, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character recognition in our publication sets. In particular the duplicate DOIs constitute a problem for the calculation of bibliometric indicators as both keeping the duplicates to improve the reliability of citation counts and deleting them to improve the reliability of publication counts will distort the calculation of average number of citations per publication. The use of UIDs as a match key in citation linking is implemented in many settings, and the availability of UIDs may become

  12. Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal - a case study from health science.

    PubMed

    Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

    2016-01-01

    Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case with publications from the health sciences. We evaluate the matching process based on information about coverage, precision, and characteristics of publications matched versus not matched with UIDs as the match keys. We analyze this information to detect errors, if any, in the matching process. As an example we also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication.  The objective is addressed in a literature review and a case study. The literature review shows that only a few studies evaluate how well UIDs work as a match key. From the literature we identify four error types: Duplicate digital object identifiers (DOI), incorrect DOIs in reference lists and databases, DOIs not registered by the database where a bibliometric analysis is performed, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character recognition in our publication sets. In particular the duplicate DOIs constitute a problem for the calculation of bibliometric indicators as both keeping the duplicates to improve the reliability of citation counts and deleting them to improve the reliability of publication counts will distort the calculation of average number of citations per publication. The use of UIDs as a match key in citation linking is implemented in many settings, and the availability of UIDs may become

  13. Modified spectral count index (mSCI) for estimation of protein abundance by protein relative identification possibility (RIPpro): a new proteomic technological parameter.

    PubMed

    Sun, Aihua; Zhang, Jiyang; Wang, Chunping; Yang, Dong; Wei, Handong; Zhu, Yunping; Jiang, Ying; He, Fuchu

    2009-11-01

    Peptides Count (SC) was widely used for protein abundance estimation in proteomics. On the basis of that, Mann and co-workers corrected the SC by dividing spectrum counts by the number of observable peptides per protein and named it PAI. Here we present modified spectral count index (mSCI) for protein abundance estimation, which was defined as the number of observed peptides divided by protein relative identification possibility (RIPpro). RIPpro was derived from 6788 mRNA and protein expression data (collected from human liver samples) and related to proteins' three physical and chemical properties (MW/pI/Hp). For 46 proteins in mouse neuro2a cells, mSCI shows a linear relationship with the actual protein concentration, similar or better than PAI abundance. Also, multiple linear regressions were performed to quantitative assess several factors' impact on the mRNA/protein abundance correlation. Our results shown that the primary factor affecting protein levels was mRNA abundance (32-37%), followed by variability in protein measurement, MW and protein turnover (7-12%,7-9% and 2-3%, respectively). Interestingly, we found that the concordance between mRNA transcripts and protein expression was not consistent among all protein functional categories. This correlation was lower for signaling proteins as compared to metabolism genes. It was determined that RIPpro was the primary factor affecting signaling protein abundance (23% on average), followed by mRNA abundance (17%). In contrast, only 5% (on average) of the variability of metabolic protein abundance was explained by RIPpro, much lower than mRNA abundance (40%). These results provide the impetus for further investigation of the biological significance of mechanisms regulating the mRNA/protein abundance correlation and provide additional insight into the relative importance of the technological parameter (RIPpro) in mRNA/protein correlation research.

  14. Impact of locomotion training with a neurologic controlled hybrid assistive limb (HAL) exoskeleton on neuropathic pain and health related quality of life (HRQoL) in chronic SCI: a case study (.).

    PubMed

    Cruciger, Oliver; Schildhauer, Thomas A; Meindl, Renate C; Tegenthoff, Martin; Schwenkreis, Peter; Citak, Mustafa; Aach, Mirko

    2016-08-01

    Chronic neuropathic pain (CNP) is a common condition associated with spinal cord injury (SCI) and has been reported to be severe, disabling and often treatment-resistant and therefore remains a clinical challenge for the attending physicians. The treatment usually includes pharmacological and/or nonpharmacological approaches. Body weight supported treadmill training (BWSTT) and locomotion training with driven gait orthosis (DGO) have evolved over the last decades and are now considered to be an established part in the rehabilitation of SCI patients. Conventional locomotion training goes along with improvements of the patients' walking abilities in particular speed and gait pattern. The neurologic controlled hybrid assistive limb (HAL®, Cyberdyne Inc., Ibraki, Japan) exoskeleton, however, is a new tailored approach to support motor functions synchronously to the patient's voluntary drive. This report presents two cases of severe chronic and therapy resistant neuropathic pain due to chronic SCI and demonstrates the beneficial effects of neurologic controlled exoskeletal intervention on pain severity and health-related quality of life (HRQoL). Both of these patients were engaged in a 12 weeks period of daily HAL®-supported locomotion training. In addition to improvements in motor functions and walking abilities, both show significant reduction in pain severity and improvements in all HRQoL domains. Although various causal factors likely contribute to abatement of CNP, the reported results occurred due to a new approach in the rehabilitation of chronic spinal cord injury patients. These findings suggest not only the feasibility of this new approach but in conclusion, demonstrate the effectiveness of neurologic controlled locomotion training in the long-term management of refractory neuropathic pain. Implications for Rehabilitation CNP remains a challenge in the rehabilitation of chronic SCI patients. Locomotion training with the HAL exoskeleton seems to improve CNP

  15. Discussion of “Geomechanical modeling of the nucleation process of Australia's 1989 M5.6 Newcastle earthquake” by C.D. Klose [Earth Planet. Sci. Lett. 256 (2007) 547 553

    NASA Astrophysics Data System (ADS)

    Quinn, C. D.; Glen, R. A.; Diessel, C. F. K.

    2008-05-01

    On the basis of a numerical simulation, Klose [Earth Planet. Sci. Lett. 256: 547-553 (2007)] proposed that the MW = 5.2-5.6 earthquake that nucleated beneath Newcastle (New South Wales, Australia) at 10.30 AM December 28, 1989 (AEST), was the result of 200yr of coal mining in the region. We argue here that Klose's [Earth Planet. Sci. Lett. 256: 547-553 (2007)] ultimate conclusion is not supported by his own model or by available geological and seismic data. In particular, the 1989 Newcastle earthquake was not anomalous with respect to regional seismic activity.

  16. SciDAC's Earth System Grid Center for Enabling Technologies Semi-Annual Progress Report for the Period April 1, 2009 through September 30, 2009

    SciTech Connect

    Williams, Dean N.; Foster, I. T.; Middleton, D. E.

    2009-10-15

    This report summarizes work carried out by the ESG-CET during the period April 1, 2009 through September 30, 2009. It includes discussion of highlights, overall progress, period goals, collaborations, papers, and presentations. To learn more about our project, and to find previous reports, please visit the Earth System Grid Center for Enabling Technologies (ESG-CET) website. This report will be forwarded to the DOE SciDAC program management, the Office of Biological and Environmental Research (OBER) program management, national and international collaborators and stakeholders (e.g., the Community Climate System Model (CCSM), the Intergovernmental Panel on Climate Change (IPCC) 5th Assessment Report (AR5), the Climate Science Computational End Station (CCES), the SciDAC II: A Scalable and Extensible Earth System Model for Climate Change Science, the North American Regional Climate Change Assessment Program (NARCCAP), and other wide-ranging climate model evaluation activities). During this semi-annual reporting period, the ESG-CET team continued its efforts to complete software components needed for the ESG Gateway and Data Node. These components include: Data Versioning, Data Replication, DataMover-Lite (DML) and Bulk Data Mover (BDM), Metrics, Product Services, and Security, all joining together to form ESG-CET's first beta release. The launch of the beta release is scheduled for late October with the installation of ESG Gateways at NCAR and LLNL/PCMDI. Using the developed ESG Data Publisher, the ESG II CMIP3 (IPCC AR4) data holdings - approximately 35 TB - will be among the first datasets to be published into the new ESG enterprise system. In addition, the NCAR's ESG II data holdings will also be published into the new system - approximately 200 TB. This period also saw the testing of the ESG Data Node at various collaboration sites, including: the British Atmospheric Data Center (BADC), the Max-Planck-Institute for Meteorology, the University of Tokyo Center for

  17. Comment on Neiser et al. Assessment of Dextran Antigenicity of Intravenous Iron Preparations with Enzyme-Linked Immunosorbent Assay (ELISA). Int. J. Mol. Sci. 2016, 17, 1185.

    PubMed Central

    Strom, Claes C.; Andreasen, Hans B.

    2017-01-01

    All IV iron complexes carry a risk of potentially fatal allergic type hypersensitivity reactions. The mechanism(s) behind these reactions is unknown but the limited data available suggests that classic IgE mediated allergy is exceedingly rare, if ever occurring. Iron–carbohydrate molecules are complex nano-particles and trying to reduce the risk of serious hypersensitivity to antibody binding of an artificial antibody seems meaningless. A recently published analysis of safety data from randomized clinical trials confirms the method reported by Neiser to be useless to predict reaction risk. In conclusion, the study by Neiser et al. is biased, contains no new information, and has no clinical relevance. We are concerned that the association of the authors with a commercial entity has caused a conflict of interest that biases not only the results, but the entire experimental setup against competitors. (Comment on Neiser et al. Int. J. Mol. Sci. 2016, 17, 1185, doi:10.3390/ijms17071185). PMID:28075402

  18. PMEL contributions to the collaboration: SCALING THE EARTH SYSTEM GRID TO PETASCALE DATA for the DOE SciDACs Earth System Grid Center for Enabling Technologies

    SciTech Connect

    Hankin, Steve

    2012-06-01

    Drawing to a close after five years of funding from DOE's ASCR and BER program offices, the SciDAC-2 project called the Earth System Grid (ESG) Center for Enabling Technologies has successfully established a new capability for serving data from distributed centers. The system enables users to access, analyze, and visualize data using a globally federated collection of networks, computers and software. The ESG software now known as the Earth System Grid Federation (ESGF) has attracted a broad developer base and has been widely adopted so that it is now being utilized in serving the most comprehensive multi-model climate data sets in the world. The system is used to support international climate model intercomparison activities as well as high profile U.S. DOE, NOAA, NASA, and NSF projects. It currently provides more than 25,000 users access to more than half a petabyte of climate data (from models and from observations) and has enabled over a 1,000 scientific publications.

  19. [SciELO Public Health: the performance of Cadernos de Saúde Pública and Revista de Saúde Pública].

    PubMed

    Barata, Rita Barradas

    2007-12-01

    The aim of this paper was to analyze two Brazilian scientific journals included in the SciELO Library of Public Health, using a group of bibliometric indicators and scrutinizing the articles most viewed. Cadernos de Saúde Pública was accessed 3,743.59 times per month, with an average of 30.31 citations per article. The 50 articles most viewed (6.72 to 524.5 views) were mostly published in Portuguese (92%). 42% were theoretical essays, 20% surveys, and 16% descriptive studies. 42% used argumentative techniques, 34% quantitative techniques, 18% qualitative techniques, and 6% mathematical modeling. The most common themes were: health and work (50%), epidemiology (22%), and environmental health (8%). Revista de Saúde Pública was accessed 1,590.97 times per month, with an average of 26.27 citations per article. The 50 articles most viewed (7.33 and 56.50 views) were all published in Portuguese: 46% were surveys, 14% databases analysis, and 12% systematic reviews. Quantitative techniques were adopted in 66% of such articles, while mathematical modeling was the same as observed in Cadernos de Saúde Pública, as were qualitative techniques. The most common themes were health services organization (22%), nutrition (22%), health and work (18%), epidemiology (12%), and environmental health (12%).

  20. Sex and Fertility After SCI

    MedlinePlus

    ... About Blog Facing Disability Jeff Shannon Donate Experts \\ Sex and Fertility After Spinal Cord Injury Topics Adult ... Spasticity, Physical Therapy-Lokomat Spasticity, Physical Therapy-Lokomat Sex and Fertility After Spinal Cord Injury Sex and ...

  1. Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: Association with recovery of forelimb function.

    PubMed

    Pawar, Kiran; Cummings, Brian J; Thomas, Aline; Shea, Lonnie D; Levine, Ariel; Pfaff, Sam; Anderson, Aileen J

    2015-10-01

    Severed axon tracts fail to exhibit robust or spontaneous regeneration after spinal cord injury (SCI). Regeneration failure reflects a combination of factors, including the growth state of neuronal cell bodies and the regeneration-inhibitory environment of the central nervous system. However, while spared circuitry can be retrained, target reinnervation depends on longitudinally directed regeneration of transected axons. This study describes a biodegradable implant using poly(lactide-co-glycolide) (PLG) bridges as a carrier scaffold to support regeneration after injury. In order to detect regeneration of descending neuronal tracts into the bridge, and beyond into intact caudal parenchyma, we developed a mouse cervical implantation model and employed Crym:GFP transgenic mice. Characterization of Crym:GFP mice revealed that descending tracts, including the corticospinal tract, were labeled by green fluorescent protein (GFP), while ascending sensory neurons and fibers were not. Robust co-localization between GFP and neurofilament-200 (NF-200) as well as GFP and GAP-43 was observed at both the rostral and caudal bridge/tissue interface. No evidence of similar regeneration was observed in mice that received gelfoam at the lesion site as controls. Minimal co-localization between GFP reporter labeling and macrophage markers was observed. Taken together, these data suggest that axons originating from descending fiber tracts regenerated, entered into the PLG bridge at the rostral margin, continued through the bridge site, and exited to re-enter host tissue at the caudal edge of the intact bridge. Finally, regeneration through implanted bridges was associated with a reduction in ipsilateral forelimb errors on a horizontal ladder task.

  2. Developing quality of care indicators for patients with traumatic and non-traumatic spinal cord injury (SCI): A feasibility study using administrative health data

    PubMed Central

    Parsons, Daria; Craven, B. Catharine; Jaglal, Susan B.; Verrier, Molly

    2015-01-01

    Objectives (1) to inform the development of health system quality indicators for traumatic and non-traumatic spinal cord injury from acute care admission to community care discharge using administrative data, and (2) to examine characteristics and differences in care among type of care facility, and type of pathology using administrative data. Design Retrospective cohort study using administrative health data. Setting Ontario, Canada. Participants Using administrative health data, we used International Classification codes 10th version Canadian Edition to identify incident cases of SCI from April 1, 2006 to March 31, 2012. Results We identified 7,693 cases in our cohort, of whom 1,537 (20.0%) were categorized as traumatic spinal cord (TSCI) and 6,156 (80.0%) as non-traumatic (NTSCI). Of those identified with NTSCI, more than half (54.0%) were diagnosed with either Guillain Barré syndrome and Multiple Sclerosis (n = 3,326). More individuals admitted to a trauma/spine center were seen by an orthopedic surgeon or a neurosurgeon (20.3% compared to 5.6% for NTSCI; 77.7% compared to 24.9% for TSCI). Only 25.7% (n = 724) of the NTSCI cohort were admitted to a rehabilitation facility from a trauma/spine center, compared to 58.9% (n = 754) of those with TSCI. Conclusions Important challenges in data completeness and utility were identified. Province wide processes to flag incomplete data and provision of incentives for comprehensive data are urgently needed to develop quality indicators across the care continuum. Consensus on the coding for NTSCI for the purposes of developing health system indicators is required. PMID:26111282

  3. Scientific Objectives of Small Carry-on Impactor (SCI) and Deployable Camera 3 Digital (DCAM3-D): Observation of an Ejecta Curtain and a Crater Formed on the Surface of Ryugu by an Artificial High-Velocity Impact

    NASA Astrophysics Data System (ADS)

    Arakawa, M.; Wada, K.; Saiki, T.; Kadono, T.; Takagi, Y.; Shirai, K.; Okamoto, C.; Yano, H.; Hayakawa, M.; Nakazawa, S.; Hirata, N.; Kobayashi, M.; Michel, P.; Jutzi, M.; Imamura, H.; Ogawa, K.; Sakatani, N.; Iijima, Y.; Honda, R.; Ishibashi, K.; Hayakawa, H.; Sawada, H.

    2016-10-01

    The Small Carry-on Impactor (SCI) equipped on Hayabusa2 was developed to produce an artificial impact crater on the primitive Near-Earth Asteroid (NEA) 162173 Ryugu (Ryugu) in order to explore the asteroid subsurface material unaffected by space weathering and thermal alteration by solar radiation. An exposed fresh surface by the impactor and/or the ejecta deposit excavated from the crater will be observed by remote sensing instruments, and a subsurface fresh sample of the asteroid will be collected there. The SCI impact experiment will be observed by a Deployable CAMera 3-D (DCAM3-D) at a distance of ˜1 km from the impact point, and the time evolution of the ejecta curtain will be observed by this camera to confirm the impact point on the asteroid surface. As a result of the observation of the ejecta curtain by DCAM3-D and the crater morphology by onboard cameras, the subsurface structure and the physical properties of the constituting materials will be derived from crater scaling laws. Moreover, the SCI experiment on Ryugu gives us a precious opportunity to clarify effects of microgravity on the cratering process and to validate numerical simulations and models of the cratering process.

  4. Glory on Venus cloud tops and the unknown UV absorber

    NASA Astrophysics Data System (ADS)

    Markiewicz, W. J.; Petrova, E.; Shalygina, O.; Almeida, M.; Titov, D. V.; Limaye, S. S.; Ignatiev, N.; Roatsch, T.; Matz, K. D.

    2014-05-01

    We report on the implications of the observations of the glory phenomenon made recently by Venus Express orbiter. Glory is an optical phenomenon that poses stringent constraints on the cloud properties. These observations thus enable us to constrain two properties of the particles at the cloud tops (about 70 km altitude) which are responsible for a large fraction of the solar energy absorbed by Venus. Firstly we obtain a very accurate estimate of the cloud particles size to be 1.2 μm with a very narrow size distribution. We also find that for the two observations presented here the clouds are homogenous, as far as cloud particles sizes are concerned, on scale of at least 1200 km. This is in contrast to previous estimates that were either local, from entry probes data, or averaged over space and time from polarization data. Secondly we find that the refractive index for the data discussed here is higher than that of sulfuric acid previously proposed for the clouds composition (Hansen, J.E., Hovenier, J.W. [1974]. J. Atmos. Sci. 31, 1137-1160; Ragent, B. et al. [1985]. Adv. Space Res. 5, 85-115). Assuming that the species contributing to the increase of the refractive index is the same as the unknown UV absorber, we are able to constrain the list of candidates. We investigated several possibilities and argue that either small ferric chloride (FeCl3) cores inside sulfuric acid particles or elemental sulfur coating their surface are good explanations of the observation. Both ferric chloride and elemental sulfur have been suggested in the past as candidates for the as yet unknown UV absorber (Krasnopolsky, V.A. [2006]. Planet. Space Sci. 54, 1352-1359; Mills, F.P. et al. [2007]. In: Esposito, L.W., Stofan, E.R., Cravens, T.E. (Eds.), Exploring Venus as a Terrestrial Planet, vol. 176. AGU Monogr. Ser., Washington, DC, pp. 73-100).

  5. Final Report- "An Algorithmic and Software Framework for Applied Partial Differential Equations (APDEC): A DOE SciDAC Integrated Software Infrastructure Center (ISIC)

    SciTech Connect

    Elbridge Gerry Puckett

    2008-05-13

    been a Deputy Section Head at the National Center for Atmospheric Research in Colorado. My understanding is that Chris Algieri is the first person that Bill hired after coming to LBNL. The plan is that Chris Algieri will finish his PhD thesis while employed as a staff scientist in Bill's group. Both Sarah and Chris were supported in part with funds from DE-FC02-01ER25473. In Sarah's case she received support both while at U.C. Davis (UCD) taking classes and writing an MS thesis and during some of the time she was living in Berkeley, working at LBNL and finishing her PhD thesis. In Chris' case he was at U.C. Davis during the entire time he received support from DE-FC02-01ER25473. More specific details of their work are included in the report below. Finally my own research conducted under the auspices of DE-FC02-01ER25473 either involved direct collaboration with researchers at LBNL - Phil Colella and Peter Schwartz who is a member of Phil's Applied Numerical Algorithms Group - or was on problems that are closely related to research that has been and continues to be conducted by researchers at LBNL. Specific details of this work can be found below. Finally, I would like to note that the work conducted by my students and me under the auspices of this contract is closely related to work that I have performed with funding from my DOE MICS contract DE-FC02-03ER25579 'Development of High-Order Accurate Interface Tracking Algorithms and Improved Constitutive Models for Problems in Continuum Mechanics with Applications to Jetting' and with my CoPI on that grant Professor Greg Miller of the Department of Applied Science at UCD. In theory I tried to use funds from the SciDAC grant DE-FC02-01ER25473 to support work that directly involved implementing algorithms developed by my research group at U.C. Davis in software that was developed and is maintained by my SciDAC CoPI's at LBNL.

  6. SciDAC Fusiongrid Project--A National Collaboratory to Advance the Science of High Temperature Plasma Physics for Magnetic Fusion

    SciTech Connect

    SCHISSEL, D.P.; ABLA, G.; BURRUSS, J.R.; FEIBUSH, E.; FREDIAN, T.W.; GOODE, M.M.; GREENWALD, M.J.; KEAHEY, K.; LEGGETT, T.; LI, K.; McCUNE, D.C.; PAPKA, M.E.; RANDERSON, L.; SANDERSON, A.; STILLERMAN, J.; THOMPSON, M.R.; URAM, T.; WALLACE, G.

    2006-08-31

    This report summarizes the work of the National Fusion Collaboratory (NFC) Project funded by the United States Department of Energy (DOE) under the Scientific Discovery through Advanced Computing Program (SciDAC) to develop a persistent infrastructure to enable scientific collaboration for magnetic fusion research. A five year project that was initiated in 2001, it built on the past collaborative work performed within the U.S. fusion community and added the component of computer science research done with the USDOE Office of Science, Office of Advanced Scientific Computer Research. The project was a collaboration itself uniting fusion scientists from General Atomics, MIT, and PPPL and computer scientists from ANL, LBNL, Princeton University, and the University of Utah to form a coordinated team. The group leveraged existing computer science technology where possible and extended or created new capabilities where required. Developing a reliable energy system that is economically and environmentally sustainable is the long-term goal of Fusion Energy Science (FES) research. In the U.S., FES experimental research is centered at three large facilities with a replacement value of over $1B. As these experiments have increased in size and complexity, there has been a concurrent growth in the number and importance of collaborations among large groups at the experimental sites and smaller groups located nationwide. Teaming with the experimental community is a theoretical and simulation community whose efforts range from applied analysis of experimental data to fundamental theory (e.g., realistic nonlinear 3D plasma models) that run on massively parallel computers. Looking toward the future, the large-scale experiments needed for FES research are staffed by correspondingly large, globally dispersed teams. The fusion program will be increasingly oriented toward the International Thermonuclear Experimental Reactor (ITER) where even now, a decade before operation begins, a large

  7. Comment on 'Etch characteristics of CeO{sub 2} thin film in Ar/CF{sub 4}/Cl{sub 2} plasma' [J. Vac. Sci. Technol. A 21, 426 (2003)

    SciTech Connect

    Paparazzo, E.

    2004-09-01

    Comments are made on a recent article by Kim, Chang, and Kim [J. Vac. Sci. Technol. A 21, 426 (2003)], which describes the preparation and the x-ray photoemission spectroscopy study of the etching effects produced by Ar-based plasmas of different composition on the surface chemistry of a CeO{sub 2} film grown on Si. We discuss some chemical interactions taking place between Ce, Si, and the ambient humidity during the early stages of film deposition, and demonstrate that the many-body effects involved in Ce 3d spectra provide a key for better understanding of the etching mechanisms exerted by the plasma treatments.

  8. Performance of Hayabusa2 DCAM3-D Camera for Short-Range Imaging of SCI and Ejecta Curtain Generated from the Artificial Impact Crater Formed on Asteroid 162137 Ryugu (1999 JU3)

    NASA Astrophysics Data System (ADS)

    Ishibashi, K.; Shirai, K.; Ogawa, K.; Wada, K.; Honda, R.; Arakawa, M.; Sakatani, N.; Ikeda, Y.

    2016-11-01

    Deployable Camera 3-D (DCAM3-D) is a small high-resolution camera equipped on Deployable Camera 3 (DCAM3), one of the Hayabusa2 instruments. Hayabusa2 will explore asteroid 162137 Ryugu (1999 JU3) and conduct an impact experiment using a liner shooting device called Small Carry-on Impactor (SCI). DCAM3 will be detached from the Hayabusa2 spacecraft and observe the impact experiment. The purposes of the observation are to know the impact conditions, to estimate the surface structure of asteroid Ryugu, and to understand the physics of impact phenomena on low-gravity bodies. DCAM3-D requires high imaging performance because it has to image and detect multiple targets of different scale and radiance, i.e., the faint SCI before the shot from 1-km distance, the bright ejecta generated by the impact, and the asteroid. In this paper we report the evaluation of the performance of the CMOS imaging sensor and the optical system of DCAM3-D. We also describe the calibration of DCAM3-D. We confirmed that the imaging performance of DCAM3-D satisfies the required values to achieve the purposes of the observation.

  9. Observations of the infrared solar spectrum from space by the ATMOS experiment.

    PubMed

    Abrams, M C; Goldman, A; Gunson, M R; Rinsland, C P; Zander, R

    1996-06-01

    The final flight of the Atmospheric Trace Molecule Spectroscopy experiment as part of the Atmospheric Laboratory for Applications and Science (ATLAS-3) Space Shuttle mission in 1994 provided a new opportunity to measure broadband (625-4800 cm(-1), 2.1-16 µm) infrared solar spectra at anunapodized resolution of 0.01 cm(-1) from space. The majority of the observations were obtained as exoatmospheric, near Sun center, absorption spectra, which were later ratioed to grazing atmospheric measurements to compute the atmospheric transmission of the Earth's atmosphere and analyzed for vertical profiles of minor and trace gases. Relative to the SPACELAB-3 mission that produced 4800 high Sun spectra (which were averaged into four grand average spectra), the ATLAS-3 mission produced some 40,000 high Sun spectra (which have been similarly averaged) with an improvement in signal-to-noise ratio of a factor of 3-4 in the spectral region between 1000 and 4800 cm(-1). A brief description of the spectral calibration and spectral quality is given as well as the location of electronic archives of these spectra.

  10. Observations of the Infrared Solar Spectrum from Space by the ATMOS Experiment

    NASA Technical Reports Server (NTRS)

    Abrams, M. C.; Goldman, A.; Gunson, M. R.; Rinsland, C. P.; Zander, R.

    1999-01-01

    The final flight of the Atmospheric Trace Molecule Spectroscopy experiment as part of the Atmospheric na Laboratory for Applications and Science (ATLAS-3) Space Shuttle mission in 1994 provided a new opportunity to measure broadband 625-4800/ cm, 2.1 - 16 micron infrared solar spectra at an unapodized resolution of 0.0l/ cm from space. The majority of the observations were obtained as exoatmospheric, of near Sun center, absorption spectra, which were later ratioed to grazing atmospheric measurements to compute the atmospheric transmission of the Earth's atmosphere and analyzed for vertical profiles of minor and trace gases. Relative to the SPACELAB-3 mission that produced 4800 high Sun spectra (which were averaged into four grand average spectra), the ATLAS-3 mission produced some 40,000 high Sun spectra (which have been similarly averaged) with an improvement in signal-to-noise ratio of a factor of 3-4 in the spectral region between 1000 and 4800/ cm. A brief description of the spectral calibration and spectral quality is given as well as the location of electronic archives of these spectra.

  11. Fairy-Tale Physics Farewell to Reality Bankrupting Physics: Baggott-Unzicker-Jones Critiques Shame Physics' Shameless Media-Hype P.R. Spin-Doctoring Touting Sci-Fi Veracity-Abandonment ``Show-Biz'' Spectacle: Caveat Emptor!!!

    NASA Astrophysics Data System (ADS)

    Siegel, Edward

    2014-03-01

    Baggott[Farewell to Reality: How Fairy-Tale Physics Betrayed Search For Scientific Truth]-Unzicker [Bankrupting Physics: How Top Scientists Are Gambling Away Credibility] shame physics shameless rock-star media-hype P.R. spin-doctoring veracity-abandoning touting sci-fi show-biz aided by online proliferation of uncritical pop-sci science-writers verbal diarrhea, all spectacle vs little truth, lacking Kant-Popper skepticism/falsification, lemming-like stampedes to truth abandonment, qualified by vague adverbs: might, could, should, may,...vs factual is! Physics, motivated by financial greed, swept up in its very own hype, touts whatever next big thing/cutting-edge bombast ad infinitum/ad nauseum, turning it into mere trendy carney sideshow, full of fury(FOF) but signifying absolutely nothing! Witness: GIGO claims string-theory holographic-universe causes cuprates optical conductivity; failed Anderson RVB cuprates theory vs. Keimer discovery all cuprates ``paramagnons'' bosons aka Overhauser SDWs; Overbye NYT holographic-universe jargonial-obfuscation comments including one from APS journals editor-in-chief re. its unintelligibility, FOF but signifying absolutely nothing INTELLIGIBLE!; Bak/BNL SOC tad late rediscovery of F =ma mere renaming of Siegel acoustic-emission!; 2007 physics Nobel-prize Fert-Gruenberg rediscovery of Siegel[JMMM 7,312(78); https://www.flickr.com/search/?q=GIANT-MAGNETORESISTANCE] GMR. Each trendy latest big thing modulo lack of prior attribution aka out and out bombastic chicanery! Siegel caveat emptor ``Buzzwordism, Bandwagonism, Sloganeering for Fun Profit Survival Ego'' sociological-dysfunctionality thrives!

  12. Fairy-Tale Physics Farewell to Reality Bankrupting Physics: Baggott-Unzicker-Jones Critiques Shame Physics' Shameless Media-Hype P.R. Spin-Doctoring Touting Sci-Fi Veracity-Abandonment ``Show-Biz'' Spectacle: Caveat Emptor!!!

    NASA Astrophysics Data System (ADS)

    Siegel, Edward

    2014-03-01

    Baggott[Farewell to Reality: How Fairy-Tale Physics Betrayed Search For Scientific Truth]-Unzicker [Bankrupting Physics: How Top Scientists Are Gambling Away Credibility] shame physics shameless rock-star media-hype P.R. spin-doctoring veracity-abandoning touting sci-fi show-biz aided by online proliferation of uncritical pop-sci science-writers verbal diarrhea, all spectacle vs little truth, lacking Kant-Popper skepticism/ falsification, lemming-like stampedes to truth abandonment, qualified by vague adverbs: might, could, should, may,...vs factual is! Physics, motivated by financial greed, swept up in its very own hype, touts whatever next big thing/cutting-edge bombast ad infinitum/ad nauseum, turning it into mere trendy carney sideshow, full of fury(FOF) but signifying absolutely nothing! Witness: GIGO claims string-theory holographic-universe causes cuprates optical conductivity; failed Anderson RVB cuprates theory vs. Keimer discovery all cuprates ``paramagnons'' bosons aka Overhauser SDWs; Overbye NYT holographic-universe jargonial-obfuscation comments including one from APS journals editor-in-chief re. its unintelligibility, FOF but signifying absolutely nothing INTELLIGIBLE!; Bak/BNL SOC tad late rediscovery of F =ma mere renaming of Siegel acoustic-emission!; 2007 physics Nobel-prize Fert-Gruenberg rediscovery of Siegel[JMMM 7,312(78); https://www.flickr.com/search/?q = GIANT-MAGNETORESISTANCE] GMR. Each trendy latest big thing modulo lack of prior attribution aka out and out bombastic chicanery! Siegel caveat emptor ``Buzzwordism, Bandwagonism, Sloganeering for Fun Profit Survival Ego'' sociological-dysfunctionality thrives!

  13. Tissue Boundaries: Mimicking Tissue Boundaries by Sharp Multiparameter Matrix Interfaces (Adv. Healthcare Mater. 15/2016).

    PubMed

    Sapudom, Jiranuwat; Rubner, Stefan; Martin, Steve; Pompe, Tilo

    2016-08-01

    Engineering interfaces of extracellular compartments mimicking native tissues is key to study cell behavior in a physiologically relevant context and for a successful translation of these new biomaterials engineering principles in regenerative and therapeutic applications. Tilo Pompe and co-workers demonstrate a strategy to engineer multiparameter matrix interfaces using a sequential reconstitution of two well-defined Collagen I based matrices on page 1861. Such matrix interfaces trigger cell migration directionality normal to the interface plane in dependence on matrix pore size.

  14. Gold Nanocups: Colloidal Gold Nanocups with Orientation-Dependent Plasmonic Properties (Adv. Mater. 30/2016).

    PubMed

    Jiang, Ruibin; Qin, Feng; Liu, Yejing; Ling, Xing Yi; Guo, Jun; Tang, Minghua; Cheng, Si; Wang, Jianfang

    2016-08-01

    On page 6322, J. F. Wang and co-workers report a wet-chemistry method for the preparation of colloidal Au nanocups and their plasmonic properties. The Au nanocups are prepared through single-vertex-initiated Au deposition on PbS nano-octahedrons and subsequent selective dissolution of PbS. Owing to the orientation-dependent coupling strengths, the obtained Au nanocups display orientation-dependent plasmonic properties and Raman enhancements when deposited on substrates.

  15. Artificial Synapses: Organometal Halide Perovskite Artificial Synapses (Adv. Mater. 28/2016).

    PubMed

    Xu, Wentao; Cho, Himchan; Kim, Young-Hoon; Kim, Young-Tae; Wolf, Christoph; Park, Chan-Gyung; Lee, Tae-Woo

    2016-07-01

    A synapse-emulating electronic device based on organometal halide perovskite thin films is described by T.-W. Lee and co-workers on page 5916. The device successfully emulates important characteristics of a biological synapse. This work extends the application of organometal halide perovskites to bioinspired electronic devices, and contributes to the development of neuromorphic electronics.

  16. Carbon Nanotubes: Printed Carbon Nanotube Electronics and Sensor Systems (Adv. Mater. 22/2016).

    PubMed

    Chen, Kevin; Gao, Wei; Emaminejad, Sam; Kiriya, Daisuke; Ota, Hiroki; Nyein, Hnin Yin Yin; Takei, Kuniharu; Javey, Ali

    2016-06-01

    Printed electronics and sensors enable new applications ranging from low-cost disposable analytical devices to large-area sensor networks. Recent progress in printed carbon nanotube electronics in terms of materials, processing, devices, and applications is discussed on page 4397 by A. Javey and co-workers. The research challenges and opportunities regarding the processing and system-level integration are also discussed for enabling of practical applications.

  17. The SciELO Brazilian Scientific Journal Gateway and Open Archives; Usability of Hypermedia Educational e-Books; Building Upon the MyLibrary Concept To Better Meet the Information Needs of College Students; Open Archives and UK Institutions; The Utah Digital Newspapers Project; Examples of Practical Digital Libraries.

    ERIC Educational Resources Information Center

    Marcondes, Carlos Henrique; Sayao, Luis Fernando; Diaz, Paloma; Gibbons, Susan; Pinfield, Stephen; Kenning, Arlitsch; Edge, Karen; Yapp, L.; Witten, Ian H.

    2003-01-01

    Includes six articles that focus on practical uses of technologies developed from digital library research in the areas of education and scholarship reflecting the international impact of digital library research initiatives. Includes the Scientific Electronic Library Online (SciELO) (Brazil); the National Science Foundation (NSF) (US); the Joint…

  18. Discussion on the article "Paleoseismological analysis of an intraplate extensional structure: the Concud fault (Iberian Chain, Eastern Spain)" by P. Lafuente, L. E. Arlegui, C. L. Liesa, and J. L. Simón (Int J Earth Sci)

    NASA Astrophysics Data System (ADS)

    Gutiérrez, Francisco; Lucha, Pedro; Guerrero, Jesús; Gutiérrez, Mateo; Carbonel, Domingo

    2012-03-01

    This discussion is focused on three aspects of the paper published by Lafuente et al. (Int J Earth Sci, doi: 10.1007/s00531-010-0542-1 , 2010) on Concud Fault, constitute the fundamental basis to assess the seismic potential of this capable structure: (1) A slip rate estimated for the Concud Fault based on an erroneous displacement value and a questionable correlation, obviating previously published datings, markedly different to those used by the authors. The wrong displacement value introduces an error of more than 25% in the calculated Quaternary slip rate. (2) A new paleoseismological interpretation of the outcrop of Condud Fault at Los Baños, adding two improperly justified paleoearthquakes to the four events previously inferred. (3) The attribution of faults affecting a young terrace to the most recent recorded earthquake on Concud Fault, ruling out implicitly the likely option of a gravitational origin for them, either landsliding or subsidence due to evaporite dissolution.

  19. Sustaining and Extending the Open Science Grid: Science Innovation on a PetaScale Nationwide Facility (DE-FC02-06ER41436) SciDAC-2 Closeout Report

    SciTech Connect

    Livny, Miron; Shank, James; Ernst, Michael; Blackburn, Kent; Goasguen, Sebastien; Tuts, Michael; Gibbons, Lawrence; Pordes, Ruth; Sliz, Piotr; Deelman, Ewa; Barnett, William; Olson, Doug; McGee, John; Cowles, Robert; Wuerthwein, Frank; Gardner, Robert; Avery, Paul; Wang, Shaowen; Lincoln, David Swanson

    2015-02-11

    Under this SciDAC-2 grant the project’s goal w a s t o stimulate new discoveries by providing scientists with effective and dependable access to an unprecedented national distributed computational facility: the Open Science Grid (OSG). We proposed to achieve this through the work of the Open Science Grid Consortium: a unique hands-on multi-disciplinary collaboration of scientists, software developers and providers of computing resources. Together the stakeholders in this consortium sustain and use a shared distributed computing environment that transforms simulation and experimental science in the US. The OSG consortium is an open collaboration that actively engages new research communities. We operate an open facility that brings together a broad spectrum of compute, storage, and networking resources and interfaces to other cyberinfrastructures, including the US XSEDE (previously TeraGrid), the European Grids for ESciencE (EGEE), as well as campus and regional grids. We leverage middleware provided by computer science groups, facility IT support organizations, and computing programs of application communities for the benefit of consortium members and the US national CI.

  20. SciDAC Computational Astrophysics Consortium

    SciTech Connect

    Burrows, Adam

    2008-06-18

    Supernova explosions are the central events in nuclear astrophysics. The core-collapse variety is a major source for the universe's heavy elements. The neutron stars, pulsars, and stellar-mass black holes of high-energy astrophysics are their products. Given their prodigious explosion energies, they are the major agencies of change in the interstellar medium, driving star formation and the evolution of galaxies. Their gas remnants are the birthplaces of the cosmic rays. Such is their brightness that they can be used as standard candles to measure the size and geometry of the universe. Recently, there is evidence that gamma-ray bursts (GRBs) originate in a small fraction of core collapses, thereby connecting two of the most energetic phenomena in the universe. However, the mechanism by which core-collapse supernovae explode has not yet been unambiguously determined. Arguably, this is one of the great unsolved problems in modern astrophysics and its investigation draws on nuclear physics, particle physics, radiative transfer, kinetic theory, gravitational physics, thermodynamics, and the numerical arts. Hence, supernovae are unrivaled astrophysical laboratories. It is the quest for the mechanism and new insights our team has recently had that motivate this proposal.

  1. Training-Induced Functional Gains following SCI

    PubMed Central

    Ward, P. J.; Herrity, A. N.; Harkema, S. J.; Hubscher, C. H.

    2016-01-01

    We previously demonstrated that daily, hour-long training sessions significantly improved both locomotor (limb kinematics, gait, and hindlimb flexor-extensor bursting patterns) and nonlocomotor (bladder function and at-level mechanical allodynia) functions following a moderate contusive spinal cord injury. The amount of training needed to achieve this recovery is unknown. Furthermore, whether this recovery is induced primarily by neuronal activity below the lesion or other aspects related to general exercise is unclear. Therefore, the current study objectives were to (1) test the efficacy of 30 minutes of step training for recovery following a clinically relevant contusion injury in male Wistar rats and (2) test the efficacy of training without hindlimb engagement. The results indicate that as little as 30 minutes of step training six days per week enhances overground locomotion in male rats with contusive spinal cord injury but does not alter allodynia or bladder function. Thirty minutes of forelimb-only exercise did not alter locomotion, allodynia, or bladder function, and neither training protocol altered the amount of in-cage activity. Taken together, locomotor improvements were facilitated by hindlimb step training for 30 minutes, but longer durations of training are required to affect nonlocomotor systems. PMID:27403345

  2. How Is Spinal Cord Injury (SCI) Diagnosed?

    MedlinePlus

    ... the standard ASIA (American Spinal Injury Association) Impairment Scale for this diagnosis. X-rays, MRIs, or more ... entire length of the spine. The ASIA Impairment Scale has five classification levels, ranging from complete loss ...

  3. Best of 2009 Sci-Tech Books

    ERIC Educational Resources Information Center

    Sapp, Gregg

    2010-01-01

    Science often reflects society's concerns, and a number of the top books of 2009 address two of the biggest headline-grabbing topics--climate change and health-care reform. This article presents a list of 35 titles that address climate change and health-care reform. Some titles cover the entirety of the global-warming threat (James Lovelock's "The…

  4. Best Sci-Tech Books of 2008

    ERIC Educational Resources Information Center

    Sapp, Gregg

    2009-01-01

    In tight economic times, the concerns and issues of science, viewed as not having enough practical value, can get pushed aside. But the top science books of 2008 demonstrate how science more often than not pays for itself. What's more practical than food (Tomorrow's Table), health (Our Daily Meds), the environment (The Hot Topics), or even--sex…

  5. Sci-Tech Archives and Manuscript Collections.

    ERIC Educational Resources Information Center

    Mount, Ellis, Ed.

    1989-01-01

    Selected collections of scientific and technical archives and manuscripts described in eight articles include the Edison Archives; American Museum of Natural History Library; MIT (Massachusetts Institute of Technology) Institute Archives and Special Collections; National Archives; Dard Hunter Paper Museum; American Zoo and Aquarium Archives; and…

  6. Weight Management Following SCI (Spinal Cord Injury)

    MedlinePlus

    ... eat more vegetables than fruits, more fruits than starches, more starches than meat and dairy foods, and more meat ... fats. 5 F OOD G ROUPS Vegetables Fruits Starches & Grains Meats & Dairies Fats & Oils Your body actually ...

  7. Treatment of Post-SCI Hypotension

    ClinicalTrials.gov

    2017-01-13

    Spinal Cord Injury; Autonomic Dysreflexia; Orthostatic Hypotension; Baroreceptor Integrity; Sympathetic Integrity; Vagal Integrity; Hypotension; Cerebral Blood Flow; Blood Pressure; Venous Occlusion Plethysmography

  8. Sensitivity of Typhoon Track Predictions in a Regional Prediction System to Initial and Lateral Boundary Conditions

    DTIC Science & Technology

    2009-09-01

    less forecast skill due to a coarser res- olution. Miguez- Macho and Paegle (2000) suggest that accurate initial and lateral boundary conditions for a...nondeveloping ver- sus developing systems. J. Atmos. Sci., 38, 1132–1151. Miguez- Macho , G., and J. Paegle, 2000: Sensitivity of a global forecast model

  9. Wave Height Characteristics in the North Atlantic Ocean: a New Approach Based on Statistical and Geometrical Techniques

    DTIC Science & Technology

    2011-11-20

    geostatistical simulations for restricted samples. On the other hand, Cai et al. (2002) applied information theoretic analysis on self-clustering of amino...assimilation system. J Atmos Ocean Sci 10(2):61–93 Iguzquiza E, Chica-Olmo M (2008) Geostatistical simulation when the number of experimental data is small: an

  10. Observational and Numerical Studies of the Boundary Layer, Cloud, and Aerosol Variability in the Southeast Pacific Coastal Marine Stratocumulus

    DTIC Science & Technology

    2012-05-01

    computed based on the method of Berger (1978). The - Eddington approximation (Joseph et al. 1976; Coakley et al. 1983) has been adopted to simulate...and J. A. Weinman, 1976: The delta- Eddington approximation for radiative flux transfer, J. Atmos. Sci., 33, 2452-2459. Katzwinkel, J., H. Siebert, and

  11. Lagrangian Coherent Structures in Tropical Cyclone Intensification

    DTIC Science & Technology

    2011-09-21

    Q. J. R. Meteorol. Soc., 120, 1111–1143, 1994. 4 Fang, J. and Zhang, F.: Initial development and genesis of Hurricane Dolly (2008), J. Atmos.5 Sci...163, doi:10.5194/acp-11-147-2011, 2011. 320 Reasor, P. D., Montgomery, M. T., and Bosart, L.: Mesoscale observations of the genesis of Hurricane Dolly

  12. Secretary of The Navy Professor

    DTIC Science & Technology

    1999-09-30

    decreases as wave height increases (for a fixed wind speed) [Willard Pierson, personal communication, 1998]. A 50-year propagating oscillation and 15...of capillary waves and sea state, J. Atmos. Sci., Vol. 56, pp. 1123 - 1139. Bourassa, M. A., L. Zamudio , and J. J. O’Brien, 1999: Non-inertial flow

  13. The Mesoscale Eddies and Kuroshio Transport in the Western North Pacific East of Taiwan from 8-year (2003-2010) Model Reanalysis

    DTIC Science & Technology

    2013-07-25

    in space and time. An oceanographic reanalysis product, on the other hand, is rarely available because global/re- gional ocean operational systems...10.1029/ 2005GL025416 Ko DS, Chao SY, Huang P, Lin SF (2009) Anomalous upwelling in Nan Wan: July 2008. Terr Atmos Ocean Sci 20(6):839–852. doi:10. 3319/TAO

  14. NOGAPS-ALPHA Simulations of the 2002 Southern Hemisphere Stratospheric Major Warming

    DTIC Science & Technology

    2006-01-01

    Northern and Southern Hemispheres (e.g., Quiroz 1986; Mechoso et al. 1988). Niishi and Nakamura (2004, here- inafter NN04) argue that the 2002 SH major...transient quasi-geostrophic eddies and its relationship with the eddy forcing of the time-mean flow. J. Atmos. Sci., 43, 1657–1678. Quiroz , R. S., 1986: The

  15. A bibliography for the conclusions to the special issue of Science of the Total Environment concerning 'The water quality of UK rivers entering the North Sea'. Sci. Tot. Environ., this volume.

    PubMed

    Neal, C; Turner, H

    2000-05-05

    In this document, a bibliography for the conclusions to the special issue of Science of the Total Environment concerning 'The water quality of UK rivers entering the North Sea'. Sci. Tot. Environ., this volume, is presented. It comprises a list of the papers presented in five special issues in learned journals, three in Science of the Total Environment (this volume and volumes 194/195, 1997 and 210/211, 1998) as well as Hydrological Processes (1999, vol 13: Special Issue, River Basin Sediment Dynamics, eds. Anderson, M.G., Peters, N.E. and Walling, D.E.) and Marine Pollution Bulletin [1999, vol 37(3-7) Special Issue: Flux of Materials between Rivers and Coastal Waters, eds. Stebbing, A.R.D., Huntley, D. and Leeks, G.J.L.]. The bibliography comprises six main sections with subsections for specific water quality issues. These are as follows: Section 1 deals with the introduction to LOIS and contained in this section is background material over the nature of the programme, the study area, remit, water quality issues and international context. Section 2 provides the main meat to the bibliography and it splits into Section 2.1 historical and Section 2.2 current water quality issues. Within Section 2.2 there are subsections dealing with specific current aspects of water quality (Section 2.2.1, major ions; Section 2.2.2, pH, dissolved carbon dioxide and dissolved oxygen; Section 2.2.3 nutrients; Section 2.2.4, trace elements; Section 2.2.5 micro-organics; Section 2.2.6 sediments; Section 2.2.7 biology). Section 3 deals with hydrology and climate variability, Section 4, modelling, Section 5 load estimation and Section 6 conclusions. A full listing of the LOIS programme is available from the LOIS programme office, CCMS, Plymouth Laboratory, Prospect Place, West Hoe, Plymouth, PL1 3DH, UK (e-mail lois@ccms.ac.uk).

  16. Novel Interphases: Synthesis, Molecular Orientation and Grafting of Liquid Crystal Polymers on Carbon Fibers

    DTIC Science & Technology

    1990-01-01

    rigid molecules into an anisotropic phase have been reported. Lars Onsager (13) showed that steric interactions between rigid rods can lead to...will eventually undergo an Onsager orientational transition. From a properties point of view the occurrence of a high density surface layer with...Plate’, N. A., Adv. in Polym. Sci., 1984, 173. (12) Flory, P. J., Proc. Royal Soc. London, 1956, A234, 73. (13) Onsager , L., Ann. N. Y. Acad. Sci

  17. Information Processing, Specificity of Practice, and the Transfer of Learning: Considerations for Reconsidering Fidelity

    ERIC Educational Resources Information Center

    Grierson, Lawrence E. M.

    2014-01-01

    Much has been made in the recent medical education literature of the incorrect characterization of simulation along a continuum of low to high fidelity (Cook et al. "JAMA" 306(9): 978-988, 2011; Norman et al. "Med Educ" 46(7): 636-647, 2012; Teteris et al. "Adv Health Sci Educ" 17(1): 137-144, 2012). For the most…

  18. Printed Biopolymer-Based Electro-Optic Device Components

    DTIC Science & Technology

    2013-07-01

    with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1...S. Sariciftci, J. G. Grote, Adv Polym Sci. DOI:10.1007/12 2009 6 [6] J. G. Grote, D. E. Diggs, R. L. Nelson, J. S. Zetts, F. K. Hopkins, N. Ogata

  19. Geomorphology and anthropogenic impact including military constraints in a microtidal wave-dominated embayment in south western Sardinia (Porto Pino beach, SCI ITB040025, Mediterranean Sea). Implications for beach management.

    NASA Astrophysics Data System (ADS)

    De Muro, Sandro; Buosi, Carla; Pusceddu, Nicola; Frongia, Paolo; Passarella, Marinella; Ibba, Angelo

    2016-04-01

    The coastal zones of the Mediterranean have undergone increasing pressure over the last century. The intensifying coastal development and the increasing tourist impact have led to an intense transformation of the coastlines and adjacent marine areas. The beach and the coastal dune play an important role in protecting the coastline. Thus, the study of its geomorphological evolution and of its anthropic modification is fundamental in order to adopt the best management practices. In this regard, the LIFE Project (LIFE13NAT/IT/001013) SOSS DUNES (Safeguard and management Of South-western Sardinian Dunes) aims to safeguard the dune habitats and the beach system in a site belonging to the Natura 2000 network, an EUwide network of nature protection areas established under the 1992 Habitats Directive. This project is focused on a microtidal wave-dominated embayment located in south western Sardinia (Italy, Mediterranean Sea) called Porto Pino beach comprised in the SCI (Site of Community Importance) "Promontory, dunes and wetland of Porto Pino (ITB040025)". This research aims to investigate the geomorphological processes, the evolution and the main human impacts on Porto Pino beach as an useful tool for both conservation and coastal management. The coastal area of Porto Pino is represented by sandy shorelines extending for a total length of 5 km characterized by a wide primary and secondary dune systems, a backshore wetland lagoon and marsh area arranged parallel to the coastline. This littoral area can be ideally divided into three parts: the first, about 600 m long, in the north-west part characterized by the highest human pressure due to touristic activity on the foredunes and deposition of beach wrack; the second part in the south-east, about 1100 m long, characterized by a complex dune system (primary and secondary foredunes); and the third southernmost part included in a military area, about 3300 m long, characterized by transgressive dune system with low human

  20. Efficient Radiative Transfer Computations in the Atmosphere.

    DTIC Science & Technology

    1981-01-01

    absorptance, A = 1 - r , the net flux at level Z is given by equation (5) Net Flux, F (Z) = I - I, = B(Zsfc) -B(Ztop) A (ZtopZ) Zsfc - sft A (Z’,Z)dB(Z’) (5) ztop 11... F . Alyea, N. Phillips and R . Prinn, 1975; A three dimensional dynamical-chemical model of atmos- pheric ozone, J. Atmos. Sci., 32:170-194. 4...AD-ADO? 289 AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH F /0 41/I EFFICIENT RADIATIVE TRANSFER COMPUTATIONS IN THE ATNOSI*ERE.fUI JAN 81 C R POSEY

  1. Educing the emission mechanism of internal gravity waves in the differentially heat rotating annulus

    NASA Astrophysics Data System (ADS)

    Rolland, Joran; Hien, Steffen; Achatz, Ulrich; Borchert, Sebastian; Fruman, Mark

    2016-04-01

    geostrophic balance. For the first stage of this investigation, we separated the flow between a balance and an imbalanced part at first order in Rossby number: the balanced pressure field was computed through an inversion of the potential vorticity equation [3]. The balanced horizontal velocity field and buoyancy were then computed using the geostrophic and hydrostatic balance conditions. We first checked that this decomposition gave on the one hand a large scaled balanced flow, comprising mostly of the baroclinic wave, and on the other hand a small scale flow comprising mostly of the gravity wave signal. We then proceeded with the central stage of the validation: we simulated the tangent linear dynamics of the imbalanced part of the flow [4]. The equations are linearised about the balanced part, and any imbalances forces the modeled imbalanced part. The output of this simulation compares very well with the actual imbalanced part, thus confirming that the observed gravity waves are indeed generated through spontaneous imbalance. To our knowledge, this is the first demonstration of emission by this mechanism in a flow which is not idealised: a flow which can be obtained as a result of a numerical simulation of primitive equations or actually observed in a laboratory experiment. References [1] R. Plougonven, F. Zhang, Internal gravity waves from atmospheric jets and fronts, Rev. Geophys. 52, 33-76 (2014). [2] S. Borchert, U. Achatz, M.D. Fruman, Spontaneous Gravity wave emission in the differentially heated annulus, J. Fluid Mech. 758, 287-311 (2014). [3] F. Zhang, S.E . Koch, C. A. Davis, M. L. Kaplan, A Survey of unbalanced flow diagnostics and their application, Adv. Atmo. Sci. 17, 165-183 (2000). [4] S. Wang, F. Zhang, Source of gravity waves within a vortex dipole jet revealed by a linear model, J. Atmo. Sci. 67, 1438-1455 (2010).

  2. Corrigendum to "Non-exhaust PM emissions from electric vehicles" [Atmos. Environ. 134 (June 2016) 10-17

    NASA Astrophysics Data System (ADS)

    Timmers, Victor R. J. H.; Achten, Peter A. J.

    2016-12-01

    The authors regret that as Victor Timmers did not carry out the research under the auspices of the University of Edinburgh, nor in collaboration or consultation with any personnel at the University of Edinburgh, the affiliation of "University of Edinburgh" has now been removed from this work at the request of the Institution. In addition, subsequent to the publication of the Paper, Victor Timmers has disclosed a potential Conflict of Interest with regard to the work, namely: "non-financial support from Innas B.V, during the conduct of the study".

  3. The results of complex optical measurements of vertical temperature profile of the atmos-phere in the winter in Yakutsk

    NASA Astrophysics Data System (ADS)

    Nikolashkin, Semyen; Ignatyev, V. M.; Ammosov, Petr; Koltovskoy, Igor; Titov, Semen; Reshetnikov, Alexander

    The results of simultaneous measurements of atmospheric temperature from 0 to 100 km by lidar, spectrometric and interferometric methods in winter 2008 in Yakutsk are presented. Temperature measurements for the surface layer from 0 to 20-25 km were obtained from radio-sonde data on upper-air station in Yakutsk. Measuring the temperature of the middle atmosphere from 25 to 55-60 km made using Rayleigh Lidar near Yakutsk, with the following parameters: a transmitter Nd-YAG laser at a wavelength of 532 nm and a pulse energy of 200 mJ receiver - a telescope with a primary mirror diameter of 60 cm and a focal length of 200 cm, with a photon counting system and a spectrum analyzer. The temperature of the upper atmosphere was meas-ured at three altitude levels: by hydroxyl emission layer at the mesopause (6,2 band) , molecular oxygen radiation using an infrared spectrograph with a CCD camera and atomic oxygen emission line 557.7 nm with Fabry-Perot spectrometer (FPS) at the Maimaga optic range. FPS aperture was 15 cm, gap 1.5 cm, plate’s reflectance 0.85 and finess12. Thus, in this work, we covered by the temperature measuring most of the atmosphere ex-cept for a layer of the mesosphere from 60 to 87 km. For comparison, also are used CIRA model and the AURA MLS instrument (MicroLimb Sounder) temperature profiles data. Data analysis showed that there is a wave-like change in the vertical temperature profile, which is the result of vertical transmission features planetary waves during a stratospheric warming. This work is supported by the Integration project of the SB RAS No. 106 and RFBR grant No. 12-05-98547-r-vostok-a.

  4. Erratum to "Predicting sulphur and nitrogen deposition using a simple statistical method" [Atmos. Environ. 140 (2016) 456-468

    NASA Astrophysics Data System (ADS)

    Oulehle, Filip; Kopáček, Jiří; Chuman, Tomáš; Černohous, Vladimír; Hůnová, Iva; Hruška, Jakub; Krám, Pavel; Lachmanová, Zora; Navrátil, Tomáš; Štěpánek, Petr; Tesař, Miroslav; Evans, Christopher D.

    2016-10-01

    The Journal regrets that the author's names were tagged incorrectly resulting in author forenames appearing as surnames. The correct author names are: Filip Oulehle, Jiří Kopáček, Tomáš Chuman, Vladimír Černohous, Iva Hůnová, Jakub Hruška, Pavel Krám, Zora Lachmanová, Tomáš Navrátil, Petr Štěpánek, Miroslav Tesař, Christopher D. Evans. The Journal would like to apologise for any inconvenience caused.

  5. The 1985 chlorine and fluorine inventories in the stratosphere based on ATMOS observations at 30 deg North latitude

    NASA Technical Reports Server (NTRS)

    Zander, R.; Gunson, M. R.; Farmer, C. B.; Rinsland, C. P.; Irion, F. W.; Mahieu, E.

    1992-01-01

    Results are presented of an investigation of the Cl and F inventories derived from the concentrations of eleven Cl- and F-bearing organic and inorganic species throughout the atmosphere, based on observations with the Atmospheric Trace Molecule Spectroscopy instrument aboard the Space Shuttle during the Spacelab 3 mission of April 29 to May 6, 1985. It was found that, in April-May 1985, near 30 deg N, the mean total stratospheric concentrations of Cl and F were 2.58 +/-0.10 ppbv and 1.15 +/-0.12 ppbv, respectively. Partitioning among the source, sink, and reservoir species was consistent with the conservation of the F and Cl budgets throughout the stratosphere. It is shown that the budgets of Cl and F above about 45 km altitude can be determined accurately by measuring only HCl, HF, and CF4 and provide a straightforward timely reference point for future inventories and trends evaluations.

  6. Organosilica: Chemistry of Mesoporous Organosilica in Nanotechnology: Molecularly Organic-Inorganic Hybridization into Frameworks (Adv. Mater. 17/2016).

    PubMed

    Chen, Yu; Shi, Jianlin

    2016-05-01

    Organic-inorganic hybrid materials can combine the advantages of organic and inorganic materials, and overcome their drawbacks accordingly. On page 3235, Y. Chen and J. L. Shi review and discuss research progress on the design, synthesis, structure, and composition control of organic-inorganic hybrid mesoporous organosilica nanoparticles (MONs). Extensive applications of MONs in nanotechnology, mainly in nanomedicine, nanocatalysis and nanofabrication are discussed.

  7. Wearable Strain Sensors: Carbonized Silk Fabric for Ultrastretchable, Highly Sensitive, and Wearable Strain Sensors (Adv. Mater. 31/2016).

    PubMed

    Wang, Chunya; Li, Xiang; Gao, Enlai; Jian, Muqiang; Xia, Kailun; Wang, Qi; Xu, Zhiping; Ren, Tianling; Zhang, Yingying

    2016-08-01

    A novel carbonized plain-weave silk-fabric-based wearable strain sensor is proposed by Y. Y. Zhang and co-workers on page 6640. The sensor can be stretched up to 500% with high sensitivity in a wide strain range and can be assembled into wearable devices for the detection of both large and subtle human activities, showing great potential in human-motion detection and robotics.

  8. Liquid Metals: Stretchable, High-k Dielectric Elastomers through Liquid-Metal Inclusions (Adv. Mater. 19/2016).

    PubMed

    Bartlett, Michael D; Fassler, Andrew; Kazem, Navid; Markvicka, Eric J; Mandal, Pratiti; Majidi, Carmel

    2016-05-01

    An all-soft-matter composite consisting of liquid metal microdroplets embedded in a soft elastomer matrix is presented by C. Majidi and co-workers on page 3726. This composite exhibits a high dielectric constant while maintaining exceptional elasticity and compliance. The image shows the composite's microstructure captured by 3D X-ray imaging using a nano-computed tomographic scanner.

  9. Flexible Batteries: Hierarchical Assemblies of Carbon Nanotubes for Ultraflexible Li-Ion Batteries (Adv. Mater. 31/2016).

    PubMed

    Ahmad, Shahab; Copic, Davor; George, Chandramohan; De Volder, Michael

    2016-08-01

    An advanced battery architecture composed of 3D carbon nanotube (CNT) current collectors is used to mitigate stresses in flexible batteries. On Page 6705, C. George, M. De Volder, and co-workers describe the fabrication process and characteristics of this new generation of ultraflexible batteries, which show high rate and cyclablility. These batteries may find applications in the powering of flexible displays and logics.

  10. Adv. Simulation for Additive Manufacturing: 11/2014 Wkshp. Report for U.S. DOE/EERE/AMO

    SciTech Connect

    Turner, John A.; Babu, Sudarsanam Suresh; Blue, Craig A.

    2015-07-01

    The overarching question for the workshop was as following: How do we best utilize advanced modeling and high-performance computing (HPC) to address key challenges and opportunities in order to realize the full potential of additive manufacturing; and what are the key challenges of additive manufacturing to which modeling and simulation can contribute solutions, and what will it take to meet these challenges?

  11. Batteries: encapsulated monoclinic sulfur for stable cycling of li-s rechargeable batteries (adv. Mater. 45/2013).

    PubMed

    Moon, San; Jung, Young Hwa; Jung, Wook Ki; Jung, Dae Soo; Choi, Jang Wook; Kim, Do Kyung

    2013-12-03

    On page 6547 Do Kyung Kim, Jang Wook Choi and co-workers describe a highly aligned and carbon-encapsulated sulfur cathode synthesized with an AAO template that exhibits a high and long cycle life, and the best rate capability based on the complete encapsulation of sulfur (physical) and implementation of the monoclinic sulfur phase (chemical).

  12. Ferromagnetism: Sulfur Doping Induces Strong Ferromagnetic Ordering in Graphene: Effect of Concentration and Substitution Mechanism (Adv. Mater. 25/2016).

    PubMed

    Tuček, Jiří; Błoński, Piotr; Sofer, Zdeněk; Šimek, Petr; Petr, Martin; Pumera, Martin; Otyepka, Michal; Zbořil, Radek

    2016-07-01

    R. Zbořil and co-workers show that doping a graphene lattice with sulfur induces magnetic centers which display ferromagnetic order below ≈62 K. As described on page 5045, sulfur doping promotes magnetically active configurations resembling the gamma-thiothiapyrone motif. Enhanced magnetic properties of sulfur-doped graphene are attributed to two unpaired electrons from each sulfur atom injected into the graphene conducting band where they are delocalized between the S and C atoms.

  13. Flexible Electronics: High Pressure Chemical Vapor Deposition of Hydrogenated Amorphous Silicon Films and Solar Cells (Adv. Mater. 28/2016).

    PubMed

    He, Rongrui; Day, Todd D; Sparks, Justin R; Sullivan, Nichole F; Badding, John V

    2016-07-01

    On page 5939, J. V. Badding and co-workers describe the unrolling of a flexible hydrogenated amorphous silicon solar cell, deposited by high-pressure chemical vapor deposition. The high-pressure deposition process is represented by the molecules of silane infiltrating the small voids between the rolled up substrate, facilitating plasma-free deposition over a very large area. The high-pressure approach is expected to also find application for 3D nanoarchitectures.

  14. 3D Printing: 3D Printing of Shape Memory Polymers for Flexible Electronic Devices (Adv. Mater. 22/2016).

    PubMed

    Zarek, Matt; Layani, Michael; Cooperstein, Ido; Sachyani, Ela; Cohn, Daniel; Magdassi, Shlomo

    2016-06-01

    On page 4449, D. Cohn, S. Magdassi, and co-workers describe a general and facile method based on 3D printing of methacrylated macromonomers to fabricate shape-memory objects that can be used in flexible and responsive electrical circuits. Such responsive objects can be used in the fabrication of soft robotics, minimal invasive medical devices, sensors, and wearable electronics. The use of 3D printing overcomes the poor processing characteristics of thermosets and enables complex geometries that are not easily accessible by other techniques.

  15. Perovskite Solar Cells: High Efficiency Pb-In Binary Metal Perovskite Solar Cells (Adv. Mater. 31/2016).

    PubMed

    Wang, Zhao-Kui; Li, Meng; Yang, Ying-Guo; Hu, Yun; Ma, Heng; Gao, Xing-Yu; Liao, Liang-Sheng

    2016-08-01

    On page 6695, X. Y. Gao, L.-S. Liao, and co-workers describe the fabrication of mixed Pb-In perovskite solar cells, using indium (III) chloride and lead (II) chloride with methylammonium iodide. A maximum power conversion efficiency as high as 17.55% is achieved owing to the high quality of the perovskites with multiple ordered crystal orientations. This work demonstrates the possibility of substituting the Pb (II) by using In (III), which opens a broad route to fabricating alloy perovskite solar cells with mitigated ecological impact.

  16. Nanoparticle Assemblies: Nanoparticle Clusters: Assembly and Control Over Internal Order, Current Capabilities, and Future Potential (Adv. Mater. 27/2016).

    PubMed

    Stolarczyk, Jacek K; Deak, Andras; Brougham, Dermot F

    2016-07-01

    Clusters or assemblies of nanoparticles exhibit unique features which arise from the enhancement of properties of single nanoparticles or due to new collective properties. On page 5400, D. F. Brougham and co-workers review the role of nanoparticle interactions in controlling cluster formation, and classify the assembly mechanisms. Emerging applications for surface-enhanced Raman scattering (SERS), optical labeling, light harvesting, magnetic resonance imaging (MRI), hyperthermia, photocatalysis, enrichment, and separation are presented. Cover image by Christoph Hohmann, Nanosystems Initiative Munich (NIM).

  17. High-Resolution Electronics: Spontaneous Patterning of High-Resolution Electronics via Parallel Vacuum Ultraviolet (Adv. Mater. 31/2016).

    PubMed

    Liu, Xuying; Kanehara, Masayuki; Liu, Chuan; Sakamoto, Kenji; Yasuda, Takeshi; Takeya, Jun; Minari, Takeo

    2016-08-01

    On page 6568, T. Minari and co-workers describe spontaneous patterning based on the parallel vacuum ultraviolet (PVUV) technique, enabling the homogeneous integration of complex, high-resolution electronic circuits, even on large-scale, flexible, transparent substrates. Irradiation of PVUV to the hydrophobic polymer surface precisely renders the selected surface into highly wettable regions with sharply defined boundaries, which spontaneously guides a metal nanoparticle ink into a series of circuit lines and gaps with the widths down to a resolution of 1 μm.

  18. Preferential and Bidirectional Labeling of the Rubrospinal Tract with Adenovirus-GFP for Monitoring Normal and Injured Axons

    PubMed Central

    Wang, Xiaofei; Smith, George M.

    2011-01-01

    Abstract The rodent rubrospinal tract (RST) has been studied extensively to investigate regeneration and remodeling of central nervous system (CNS) axons. Currently no retrograde tracers can specifically label rubrospinal axons and neurons (RSNs). The RST can be anterogradely labeled by injecting tracers into the red nucleus (RN), but accurately locating the RN is a technical challenge. Here we developed a recombinant adenovirus carrying a green fluorescent protein reporter gene (Adv-GFP) which can preferentially, intensely, and bi-directionally label the RST. When Adv-GFP was injected into the second lumbar spinal cord, the GFP was specifically transported throughout the entire RST, with peak labeling seen at 2 weeks post-injection. When Adv-GFP was injected directly into the RN, GFP was anterogradely transported throughout the RST. Following spinal cord injury (SCI), injection of Adv-GFP resulted in visualization of GFP in transected, spared, or sprouted RST axons bi-directionally. Thus Adv-GFP could be used as a novel tool for monitoring and evaluating strategies designed to maximize RST axonal regeneration and remodeling following SCI. PMID:21299337

  19. Large-scale Rossby Normal Modes during Some Recent Northern Hemisphere Winters

    DTIC Science & Technology

    2011-01-01

    prescribed climatological background winds and temperatures typical of solstice and equinox. Salby (1981a) also showed that inhomogeneities in the...relatively undisturbed and eastward. The amplitude of the normal modes is substantially biased toward the winter hemisphere near solstice when...modes in nonuniform background configurations. Part II: Equinox and solstice conditions. J. Atmos. Sci., 38, 1827-1840. Salby, M.L., 1984. Transient

  20. Models of Weather Environments Adverse to Electro-Optical Systems.

    DTIC Science & Technology

    1981-09-01

    think that Army users could be satisfied witlt only macro- scale data. In turn, the macro- physicist feels threatened when told only extensive...16, (1973). Blanchard, D.C., and Spencer, A.T., " Experiments on the Generation of Raindrop-Size Distributions by Drop Breakup," J. Atmos. Sci., 27...R.G., "Rainfall Attenuation of Centimeter Waves: Comparison of Thoery and Measurement," Tefe Transactions on antennas and Propagation, ed. Falcone, pp

  1. Initialization, Prediction and Diagnosis of the Rapid Intensification of Tropical Cyclones using the Australian Community Climate and Earth System Simulator, ACCESS

    DTIC Science & Technology

    2011-11-23

    diabatic processes act as PV sources and sinks. Furthermore, when the traditional equation is applied to convective systems there can be very large...when friction and diabatic processes are present. The implication of this result is profound, i.e., for most atmospheric systems PV is to a large... diabatic heating and frictional or other forces. J. Atmos. Sci., 44, 828—841. Kepert, J. D. and Y. Wang, 2001: The dynamics of boundary layer jets

  2. A Framework to Evaluate Unified Parameterizations for Seasonal Prediction: An LES/SCM Parameterization Test-Bed

    DTIC Science & Technology

    2012-09-30

    Figure 8: Liquid water path at t = 24 h. 5 Figure 1: Shallow cumulus clouds during BOMEX after 12 hours of...1993: Large-eddy simulation of trade-wind cumulus clouds . J. Atmos. Sci., 50, 3894–3908. Misra, A. and D. I. Pullin, 1997: A vortex-based subgrid...Simulations to study the stratocumulus to shallow- cumulus cloud transition. J. Atmospheric Sciences, in press.  Chung, D. and G. Matheou, 2012: Large-eddy

  3. Modeling Interaction of a Tropical Cyclone with Its Cold Wake

    DTIC Science & Technology

    2014-09-01

    Atmos. Sci., 43, 585-605. Fairall, C., E. Bradley , J. Hare, A. Grachev, and J. Edson, 2003: Bulk Parameterization of Air-Sea Fluxes: Updates and... Carroll , C. Rowley, O. M. Smedstad, P. Chu, B. Lunde, J. Shriver, and R. Helber, 2011: Validation test report for the Navy Coupled Ocean Data...S. Gabersek, D. Wang, S. Carroll , and R. Allard, 2012: Ocean-wave coupled modeling in COAMPS-TC: A study of Hurricane Ivan (2004). Ocean Dynamics

  4. Semidiurnal Hough Mode Extensions in the Thermosphere and Their Application

    DTIC Science & Technology

    1977-02-01

    OF TNIS PAGE (11t~n Veto Rnforod) ..- q4ITY CLASSIFICATION OF THIS PAGE(Whan Dae EFneld) 20. Abstract (Continued) solar cycle. This note gives the...will vary with solar cycle insofar as ion drag (proportional to electron density) and neutral temperature vary with the solar cycle. To present the...Reidel, Dordrecht, Holland, 200 pp. 2. Hong, S., and R. S. Lindzen, 1976, Solar Semidiurnal Tide in the Thermosphere. J. Atmos. Sci., a, in press. 3

  5. Using Enthalpy as a Prognostic Variable in Atmospheric Modelling with Variable Composition

    DTIC Science & Technology

    2016-04-14

    10.1029/2007GL032911. Hauf T, Höller H. 1987. Entropy and potential temperature . J. Atmos. Sci. 44: 2887–2901. Hirschfelder JO, Curtiss CF, Bird RF...moist air. This choice presents a general and flexible alternative to the common formalism of virtual temperature employed in most numerical weather...formulation. Published in 2008 by John Wiley & Sons, Ltd. KEY WORDS entropy; internal energy equation; thermodynamic potentials; virtual temperature Received 6

  6. Front-Boundary Layer Models from STORM-FEST Observations

    DTIC Science & Technology

    1994-05-02

    represents an analysis of deformation fronto- genesis that occurred on 21 February 1992. This case represents almost a text book example of a...Study Rtegion and Data Set iii) 1ewsIults( and Statistical Analysis 1)) Realistic loitsineq Equations Frontogenesis Model -4- William Blumen F49620-93-1...114,1201-1219. Hoskins, B.J. and F.P. Bretherton, 1972: Atmospheric frotogenesis models: matematical formulation and solution. J.Atmos. Sci., 29,11-37

  7. The transition from symmetric to baroclinic instability in the Eady model

    NASA Astrophysics Data System (ADS)

    Stamper, Megan A.; Taylor, John R.

    2017-01-01

    Here, we explore the transition from symmetric instability to ageostrophic baroclinic instability in the Eady model; an idealised representation of a submesoscale mixed layer front. We revisit the linear stability problem considered by Stone (J Atmos Sci, 23, 390-400, (Stone 1966)), Stone (J Atmos Sci, 27, 721-726, (Stone 1970)), Stone (J Atmos Sci, 29, 419-426, (Stone 1972)) with a particular focus on three-dimensional `mixed modes' (which are neither purely symmetric or baroclinic) and find that these modes can have growth rates within just a few percent of the corresponding two-dimensional growth rate maximum. In addition, we perform very high resolution numerical simulations allowing an exploration of the transition from symmetric to baroclinic instability. Three-dimensional mixed modes represent the largest contribution to the turbulent kinetic energy during the transition period between symmetric and baroclinic instability. In each simulation, we see the development of sharp fronts with associated high rms vertical velocities of up to 30 mm s-1. Furthermore, we see significant transfer of energy to small scales, demonstrated by time-integrated mixing and energy dissipation by small-scale three-dimensional turbulence totalling about 30 % of the initial kinetic energy in all cases.

  8. Sci-Tech Feature: Plutonium. Fuel for Controversy.

    ERIC Educational Resources Information Center

    Iikubo, Ryuko

    1993-01-01

    Despite opposition by environmental organizations, Japan plans to import plutonium from France and Great Britain. Interviews Toichi Sakata, director of the nuclear fuel division of the Science and Technology Agency, who explains why Japan needs the radioactive substance. (MDH)

  9. Final report for Utah State's SciDAC CEMM contribution

    SciTech Connect

    Dr. Eric Held

    2008-05-13

    This document represents a summary of work carried out at Utah State University in conjunction with the Center for Extended Magnetohyrodynamic Modeling (CEMM). The principal investigator, Dr. Eric Held, was aided in this work by two former graduate students, Drs. John James and Michael Addae-Kagyah, who completed their PhD's while being partially funded by CEMM monies. In addtion, Dr. Jeong-Young Ji, a postdoctoral researcher and Mukta Sharma, a graduate student were supported. The work associated with this grant focused on developing an efficient, hybrid fluid/kinetic model for fusion plasmas. Specifically, expressions for the parallel heat fluxes and stresses in magnetized plasmas were implemented and exercised in the NIMROD plasma fluid code.

  10. Falling for sport: a case report of skydiving and SCI.

    PubMed

    Esser, Stephan M; Baima, Jennifer; Hirschberg, Ronald

    2013-01-01

    Participation in extreme sports has increased over the last 25 years. Although spinal cord injury may be sustained during extreme and traditional sports alike, the associated risk, location, and severity of injury varies by sport. We describe the case of a 31-year-old man who sustained an L1 burst fracture while landing his inaugural skydiving jump. He developed a mixed pattern of neurologic injury with relative preservation of lower extremity strength and impaired bowel and bladder function. Sports medicine providers should be aware of the risks associated with air sports/extreme sports participation. Such awareness may help prevent injury and enhance the management of associated complications.

  11. What Are the Treatments for Spinal Cord Injury (SCI)?

    MedlinePlus

    ... transport the patient to the hospital In the Emergency Room Once the patient is at the hospital, ... for communication Occupational therapy focused on fine motor skills Techniques for self-grooming and bladder and bowel ...

  12. An Implantable Neuroprosthetic Device to Normalize Bladder Function after SCI

    DTIC Science & Technology

    2012-10-01

    alternating Page 26 19 current on axonal conduction through the vagus nerve ,” J. Neural Eng., vol.8, 056031, 2011. [3] C. Tai, J.R. Roppolo, W.C. de...Wattaja, J.J., Tweden, K.S., Honda, C.N. (2011). Effects of high frequency alternating current on axonal conduction through the vagus nerve . Journal of...design the novel neuroprosthetic device. Based on our previous studies, we propose in this project to use pudendal nerve stimulation and blockade to

  13. An Implantable Neuroprosthetic Device to Normalize Bladder Function after SCI

    DTIC Science & Technology

    2013-10-01

    high frequency blocking stimulation has also been verified by recent clinical studies to block the vagus nerve for diabetes treatment. 12,13 The...alternating current on axonal conduction through the vagus nerve . J Neural Eng 2011; 8:056013. FIGURE CAPTIONS Fig.1. The implantable stimulator (A...on our previous studies, we propose in this project to use pudendal nerve stimulation and blockade to restore both continence and micturition after

  14. Molecular Determinants Fundamental to Axon Regeneration After SCI

    DTIC Science & Technology

    2011-01-01

    Months 1-18) Introduction: The zebrafish spinal cord model system is unique because of the co-existence of brainstem neurons that do ( regenerators ) and...3: To identify genes involved in axon regeneration from brainstem neurons in the injured adult zebrafish spinal cord. Experiments will be...performed to label brainstem neurons with fast blue that do or do not, regenerate an axon across an injury in the adult zebrafish spinal cord. Non

  15. Molecular Determinants Fundamental to Axon Regeneration After SCI

    DTIC Science & Technology

    2010-07-01

    1-12) Introduction: The zebrafish spinal cord model system is unique because of the co-existence of brainstem neurons that do ( regenerators ) and...11 SOW: Specifc Aim 3: To identify genes involved in axon regeneration from brainstem neurons in the injured adult zebrafish spinal cord...Experiments will be performed to label brainstem neurons with fast blue that do or do not, regenerate an axon across an injury in the adult zebrafish

  16. Molecular Determinants Fundamental to Axon Regeneration after SCI

    DTIC Science & Technology

    2012-06-01

    will determine the relationship between L1.1 and neurocan and its role in axon regeneration from adult zebrafish brainstem neurons in vitro. The...determine the relationship between L1.1 and neurocan and its role in axon regeneration from adult zebrafish brainstem neurons in vitro. Increased...concerning the potential interactions between neurocan and L1 and the role they play in axonal regeneration seen in the zebrafish . 18 Figure

  17. CitSci.org: Multi-Scale Citizen Science Support

    NASA Astrophysics Data System (ADS)

    Newman, G. J.; Crall, A.; Graham, J.; Laituri, M.

    2011-12-01

    Citizen science and community-based monitoring programs are increasing in number and breadth, generating volumes of scientific data. Many programs are ill-equipped to effectively manage these data. We examined the art and science of multi-scale citizen science support, focusing on issues of integration and flexibility that arise when programs span multiple spatial, temporal, and social scales across many domains. Our objectives were to: (1) review existing citizen science approaches and data management needs; (2) develop a cyber-infrastructure to support citizen science program needs; and (3) describe lessons learned. We find that approaches differ in scope, scale, and activities and that citizen science programs need best practices for data collection, standardization, integration and analysis. We built a multi-scale cyber-infrastructure support system for citizen science programs (www.citsci.org) and show that carefully designed systems can support individual program requirements while promoting interoperability necessary for cross-program meta-analyses. The system allows users with different levels of permission to themselves easily customize features and attributes they wish to collect, while adhering to a growing user-contributed, yet vetted, set of attributes necessary for cross-discipline comparisons and meta-analyses. Program evaluation integrated into the cyber-infrastructure will improve our ability to track effectiveness. We discuss the importance of standards for interoperability and the challenges associated with system maintenance and long-term support and conclude by offering a vision of the future of citizen science data management and cyber-infrastructure support.

  18. Try Sci Fi for Reading That's Out of This World!

    ERIC Educational Resources Information Center

    Bell, Robert; Zjawin, Dorothy

    1983-01-01

    Teachers can capitalize on children's interest in recent science fiction movies by using books based on the films in their classrooms. Books taken from "E. T.,""Star Wars,""The Empire Strikes Back," and "The Wrath of Khan" are summarized, and learning activities to be used in conjunction with the books are suggested. (PP)

  19. Q&A: The sci-fi optimist

    NASA Astrophysics Data System (ADS)

    Merali, Zeeya

    2014-09-01

    Best-selling science-fiction writer Neal Stephenson's works cover everything from cryptography to Sumerian mythology. Ahead of next year's novel Seveneves, he talks about his influences, the stagnation in material technologies, and Hieroglyph, the forthcoming science-fiction anthology that he kick-started to stimulate the next generation of engineers.

  20. NASA SCI Files - The Case of The Zany Animal Antics

    NASA Video Gallery

    This video covers the animal kingdom, how animals are classified, their basic needs, the food chain, reproduction and why animals migrate. Also learn about animal populations and habitats, endanger...

  1. SciDAC - Center for Plasma Edge Simulation - Project Summary

    SciTech Connect

    Parker, Scott

    2014-11-03

    Final Technical Report: Center for Plasma Edge Simulation (CPES) Principal Investigator: Scott Parker, University of Colorado, Boulder Description/Abstract First-principle simulations of edge pedestal micro-turbulence are performed with the global gyrokinetic turbulence code GEM for both low and high confinement tokamak plasmas. The high confinement plasmas show a larger growth rate, but nonlinearly a lower particle and heat flux. Numerical profiles are obtained from the XGC0 neoclassical code. XGC0/GEM code coupling is implemented under the EFFIS (“End-to-end Framework for Fusion Integrated Simulation”) framework. Investigations are underway to clearly identify the micro-instabilities in the edge pedestal using global and flux-tube gyrokinetic simulation with realistic experimental high confinement profiles. We use both experimental profiles and those obtained using the EFFIS XGC0/GEM coupled code framework. We find there are three types of instabilities at the edge: a low-n, high frequency electron mode, a high-n, low frequency ion mode, and possibly an ion mode like kinetic ballooning mode (KBM). Investigations are under way for the effects of the radial electric field. Finally, we have been investigating how plasmas dominated by ion-temperature gradient (ITG) driven turbulence, how cold Deuterium and Tritium ions near the edge will naturally pinch radially inward towards the core. We call this mechanism “natural fueling.” It is due to the quasi-neutral heat flux dominated nature of the turbulence and still applies when trapped and passing kinetic electron effects are included. To understand this mechanism, examine the situation where the electrons are adiabatic, and there is an ion heat flux. In such a case, lower energy particles move inward and higher energy particles move outward. If a trace amount of cold particles are added, they will move inward.

  2. SciDAC Visualization and Analytics Center for Enabling Technologies

    SciTech Connect

    Joy, Kenneth I.

    2014-09-14

    This project focuses on leveraging scientific visualization and analytics software technology as an enabling technology for increasing scientific productivity and insight. Advances in computational technology have resulted in an "information big bang," which in turn has created a significant data understanding challenge. This challenge is widely acknowledged to be one of the primary bottlenecks in contemporary science. The vision for our Center is to respond directly to that challenge by adapting, extending, creating when necessary and deploying visualization and data understanding technologies for our science stakeholders. Using an organizational model as a Visualization and Analytics Center for Enabling Technologies (VACET), we are well positioned to be responsive to the needs of a diverse set of scientific stakeholders in a coordinated fashion using a range of visualization, mathematics, statistics, computer and computational science and data management technologies.

  3. Sci-Fi, Storytelling, and New-Media Literacy

    ERIC Educational Resources Information Center

    Subramaniam, Mega; Ahn, June; Waugh, Amanda; Druin, Allison

    2012-01-01

    Understanding how to better engage young students in science, technology, engineering, and math (STEM) is essential. The constraints of U.S. K-12 schools (e.g. insufficient institutional supports, lack of technology access, testing pressures, etc.) often make it difficult to create truly engaging STEM curricula with which students can deeply…

  4. Restoring Bladder Function by Spinal Cord Neuromodulation in SCI

    DTIC Science & Technology

    2015-10-01

    Doc/0/6AJR79U394LKPCNU2NDHOP0LE4/fromString.html 17/47 Social  Security Number Medical Record Number Health Plan Numbers Account Numbers License...4.1 If  social  security numbers will be collected explain why they are necessary, how they will be used, how they will be protected and how long they...will be retained. Social  Security Numbers are used for reimbursement. They will be protected by being kept in a locked file cabinet in a lockedroom

  5. Treatment of Neuropathic Pain after SCI with a Catalytic Oxidoreductant

    DTIC Science & Technology

    2015-10-01

    chronic morphine tolerance in a mouse model under conditions previously reported for earlier analogs MnTE(or nHex)-2-PyP5+ ([21] [Warner et al...Batinic‐Haberle, I. Pharmacokinetics, Brain  Hippocampus  and Cortex, and  Mitochondrial Accumulation of a New Generation of Lipophilic Redox‐Active...parameter that dominates the efficacy of metalloporphyrins in blocking the  development of  morphine  antinociceptive tolerance through peroxynitrite‐mediated

  6. Treatment of Neuropathic Pain after SCI with a Catalytic Oxidoreductant

    DTIC Science & Technology

    2014-10-01

    shown the potency of MnTnBuoE-2-PyP5+ in suppressing chronic morphine tolerance in a mouse model under conditions previously reported for earlier...Rajic, Z.; Warner, D. S.;  Clair, D. K.; Huang, T. T.; Batinic‐Haberle, I. Pharmacokinetics, Brain  Hippocampus  and Cortex, and  Mitochondrial...Salvemini, D.  Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the  development of  morphine

  7. Molecular Determinants Fundamental to Axon Regeneration after SCI

    DTIC Science & Technology

    2014-09-01

    Figure 10. Zebrafish Spinal cord transection. Isolated spinal column of transected zebrafish spinal cord (rostral to left), panel A. Arrows...mammalian spinal cord, axon regeneration is frustrated by inhibitors such as chondroitin sulfate proteoglycans (CSPGs) expressed by reactive astrocytes...present at the injury site. In adult zebrafish, Danio rerio, some brainstem neuronsare able to grow their axon beyond a spinal cord injury, even

  8. SciDAC Center for Plasma Edge Simulation

    SciTech Connect

    Lin, Zhihong

    2013-12-17

    This project with a total funding of $592,998 for six years has partially supported four postdoctoral researchers at the University of California, Irvine (UCI). The UCI team has formulated electrostatic and electromagnetic global gyrokinetic particle simulation models with kinetic electrons, implemented these models in the edge code XGC1, performed benchmark between GTC and XGC1, developed computational tools for gyrokinetic particle simulation in tokamak edge geometry, and initiated preparatory study of edge turbulence using GTC code. The research results has been published in 12 papers and presented at many international and national conferences.

  9. Molecular Determinants Fundamental to Axon Regeneration after SCI

    DTIC Science & Technology

    2012-10-01

    swimming ) recovery will be assessed through analysis of a number of parameters related to swimming behavior. Functional recovery will be correlated...small piece of Gelfoam containing either PTPσ morpholino or control morpholino will be placed in the transection site. Functional ( swimming ... swimming ) recovery analysis will be performed. We have established a low-cost video tracking system that utilizes a video camera and computer monitor to

  10. SciDAC-Center for Plasma Edge Simulation Report

    SciTech Connect

    Parker, Steven

    2013-12-24

    The Common Component Architecture (CCA) effort is the embodiment of a long-range program of research and development into the formulation, roles, and use of component technologies in high-performance scientific computing. CCA components can interoperate with other components in a variety of frameworks, including SCIRun2 from the University of Utah. The SCIRun2 framework is also developing the ability to connect components from a variety of different models through a mechanism called meta-components. The meta component model operates by providing a plugin architecture for component models. Abstract components are manipulated and managed by the SCIRun2 framework, while concrete component models perform the actual work and communicate with each other directly. We will leverage the SCIRun2 framework and the Kepler system to orchestrate components in the Fusion Simulation Project (FSP) and to provide a CCA-based interface with Kepler. The groundwork for this functionality is being performed with the Scientific Data Management center. The SDM center is developing CCA-compliant interfaces for expressing and executing workflows and create workflow components based on SCIRun and Ptolemy (Kepler) execution engines, including development of uniform interfaces for selecting, starting, and monitoring scientific workflows. Accomplishments include Introduction to CCA and Simulation Software Systems, Introduction into SCIRun2 and Bridging within SCIRun2, CCALoop: A scalable design for a distributed component framework, and Combining Workflow methodologies with Component Architectures.

  11. End-User Training for Sci-Tech Databases.

    ERIC Educational Resources Information Center

    Mount, Ellis, Ed.

    1989-01-01

    Issues related to end-user training for scientific and technical online databases are discussed in five articles. Topics covered include instruction in the use of controlled and natural language vocabularies; a planning assessment for end-user searching; the role of the information center in industrial research; training for health care…

  12. Fitness and Independence after SCI: Defining Meaningful Change and Thresholds

    DTIC Science & Technology

    2015-10-01

    PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE October 2015 2. REPORT TYPE Annual 3. DATES COVERED 29 Sep 2014 - 28 Sep...Coordinate with Sites for annual IRB** report for continuing review Key Outcomes:  Local IRB approval at UM, NRH, GMU achieved  HRPO approval for...possible? 7. If we could provide a report that described how your fitness level is affecting your ability to perform daily activities in a manner that

  13. A Nonlinear Transfer Operator Theorem

    NASA Astrophysics Data System (ADS)

    Pollicott, Mark

    2017-02-01

    In recent papers, Kenyon et al. (Ergod Theory Dyn Syst 32:1567-1584 2012), and Fan et al. (C R Math Acad Sci Paris 349:961-964 2011, Adv Math 295:271-333 2016) introduced a form of non-linear thermodynamic formalism based on solutions to a non-linear equation using matrices. In this note we consider the more general setting of Hölder continuous functions.

  14. Increasing Breast Cancer Surveillance among African American Breast Cancer Survivors

    DTIC Science & Technology

    2007-07-01

    predictors of surveillance and follow-up care is Baldwin’s Afrocentric model for describing AA women’s participation in breast and cervical cancer screening...African American women’s participation in breast and cervical cancer early detection and screening. Adv Nurs Sci. 1996;19(2):27Y42. 28. Marin G. Subjective...AD_________________ Award Number: DAMD17-03-1-0454 TITLE: Increasing Breast Cancer Surveillance

  15. Studies of Ionospheric Irregularities: Origins and Effects

    DTIC Science & Technology

    2007-09-30

    and Ionospheric Scintillations that can be found at: GPS and ionospheric scintillations, P.M. Kintner, B.M. Ledvina , and E.R. de Paula, Space... Ledvina , and P.M. Kintner, Measurements of equatorial scintillations on the WAAS satellite signal, Radio Sci., submitted, 2005. [refereed] 7...Adv. Space Res., 31(3), 741-747, 2003. [refereed] Humphreys, T.E., B.M. Ledvina , M.L. Psiaki, A.P. Cerruti, and P.M. Kintner, Analysis of

  16. Corrigendum to "Vertical and horizontal concentration profiles from a tracer experiment in an heterogeneous urban area" [Atmos. Res. 154C (2015) 126-137

    NASA Astrophysics Data System (ADS)

    Connan, O.; Laguionie, P.; Maro, D.; Hébert, D.; Mestayer, P. G.; Rodriguez, F.; Rodrigues, V.; Rosant, J. M.

    2016-03-01

    The authors regret that a co-author was missed in the original article. They would like to add Dr. M. Francis as a co-author of this article. His affiliation is IRSN/PRP-ENV/SERIS, Laboratoire de Radioécologie, Cherbourg-Octeville, France.

  17. Corrigendum to "Measuring the 3-D wind vector with a weight-shiftmicrolight aircraft" published in Atmos. Meas. Tech., 4, 1421-1444, 2011

    NASA Astrophysics Data System (ADS)

    Metzger, S.; Junkermann, W.; Butterbach-Bahl, K.; Schmid, H. P.; Foken, T.

    2011-07-01

    This study investigates whether the 3-D wind vector can be measured reliably from a highly transportable and low-cost weight-shift microlight aircraft. We draw up a transferable procedure to accommodate flow distortion originating from the aircraft body and -wing. This procedure consists of the analysis of aircraft dynamics and seven successive calibration steps. For our aircraft the horizontal wind components receive their greatest single amendment (14 %, relative to the initial uncertainty) from the correction of flow distortion magnitude in the dynamic pressure computation. Conversely the vertical wind component is most of all improved (31 %) by subsequent steps considering the 3-D flow distortion distribution in the flow angle computations. Therein the influences of the aircraft's trim (53 %), as well as changes in the aircraft lift (16 %) are considered by using the measured lift coefficient as explanatory variable. Three independent lines of analysis are used to evaluate the quality of the wind measurement: (a) A wind tunnel study in combination with the propagation of sensor uncertainties defines the systems input uncertainty to ≈0.6 m s-1 at the extremes of a 95 % confidence interval. (b) During severe vertical flight manoeuvres the deviation range of the vertical wind component does not exceed 0.3 m s-1. (c) The comparison with ground based wind measurements yields an overall operational uncertainty (root mean square error) of ≈0.4 m s-1 for the horizontal and ≈0.3 m s-1 for the vertical wind components. No conclusive dependence of the uncertainty on the wind magnitude (<8 m s-1) or true airspeed (ranging from 23-30 m s-1) is found. Hence our analysis provides the necessary basis to study the wind measurement precision and spectral quality, which is prerequisite for reliable Eddy-Covariance flux measurements.

  18. Corrigendum to "Staggering reductions in atmospheric nitrogen dioxide across Canada in response to legislated transportation emissions reductions" [Atmos. Environ. 146 (December 2016) 252-260

    NASA Astrophysics Data System (ADS)

    Reid, Holly; Aherne, Julian

    2017-02-01

    The authors regret that Fig. 2 was inadvertantly replicated under Fig. 3, resulting in the omission of Fig. 3. As such Fig. 3 is provided here. The authors would like to apologise for any inconvenience caused.

  19. Corrigendum to "Chemical apportionment of southern African aerosol mass and optical depth" published in Atmos. Chem. Phys., 9, 7643-7655, 2009

    NASA Astrophysics Data System (ADS)

    Magi, B. I.

    2011-05-01

    A correction to results by Magi (2009) is presented here. By combining the in situ measurements of speciated aerosol mass concentrations with concurrent measurements of total aerosol optical properties at a wavelength of 550 nm, it is shown that ~66 % of scattering is due to carbonaceous aerosol, where derived mass scattering cross sections (MSC) for OC and BC are 3.8 ± 0.5 m2 g-1 and 2.9 ± 0.8 m2 g-1, respectively. Derived values of mass absorption cross sections (MAC) for OC and BC are 0.7 ± 0.2 m2 g-1 and 12.1 ± 0.8 m2 g-1, respectively. The values of MAC imply that ~21 % of the mid-visible aerosol absorption in southern Africa is due to OC, with the remainder due to BC. SSA for BC and OC are about the same as Magi (2009). The results here are determined using an approach that accounts for the fact that OC and BC are partially scattering and absorbing.

  20. From channel-forming ionic liquid crystals exhibiting humidity-induced phase transitions to nanostructured ion-conducting polymer membranes (adv. Mater. 26/2013).

    PubMed

    Zhang, Heng; Li, Lei; Möller, Martin; Zhu, Xiaomin; Rueda, Jaime J Hernandez; Rosenthal, Martin; Ivanov, Dimitri A

    2013-07-12

    A novel wedge-shaped amphiphilic molecule bearing a sulfonate group at the tip displays humidity-induced phase transitions from a hexagonal columnar structure to a bicontinuous cubic phase. The mesophases can be frozen by photopolymerization of acrylic end-groups resulting in free-standing membranes with different topology of ionic nanochannels. The obtained membranes with a well-ordered ionic channel structure hold promise for applications in separation and catalysis.

  1. Photoacoustic Imaging: Semiconducting Oligomer Nanoparticles as an Activatable Photoacoustic Probe with Amplified Brightness for In Vivo Imaging of pH (Adv. Mater. 19/2016).

    PubMed

    Miao, Qingqing; Lyu, Yan; Ding, Dan; Pu, Kanyi

    2016-05-01

    Despite the great potential of photoacoustic imaging in the life sciences, the development of smart activatable photoacoustic probes remains elusive. On page 3662, K. Pu and co-workers report a facile nanoengineering approach based on semiconducting oligomer nano-particles to develop ratiometric photoacoustic probes with amplified brightness and enhanced sensing capability for accurate photoacoustic mapping of pH in the tumors of living mice.

  2. Solar Cells: Homo-Tandem Polymer Solar Cells with VOC >1.8 V for Efficient PV-Driven Water Splitting (Adv. Mater. 17/2016).

    PubMed

    Gao, Yangqin; Le Corre, Vincent M; Gaïtis, Alexandre; Neophytou, Marios; Hamid, Mahmoud Abdul; Takanabe, Kazuhiro; Beaujuge, Pierre M

    2016-05-01

    On page 3366, P. M. Beaujuge and co-workers describe homo-tandem solar cells constructed by stacking identical subcells solution-processed from blends of the wide-bandgap polymer donor PBDTTPD and the fullerene acceptor PCBM, which achieve power conversion efficiencies >8% and open-circuit voltages >1.8 V. The homo-tandem devices provide sufficient voltage to induce the dissociation of water in an electrochemical cell. The authors acknowledge Hyun Ho Hwang (Heno) for developing the artwork.

  3. Sensors: A Highly Sensitive Diketopyrrolopyrrole-Based Ambipolar Transistor for Selective Detection and Discrimination of Xylene Isomers (Adv. Mater. 21/2016).

    PubMed

    Wang, Bin; Huynh, Tan-Phat; Wu, Weiwei; Hayek, Naseem; Do, Thu Trang; Cancilla, John C; Torrecilla, Jose S; Nahid, Masrur Morshed; Colwell, John M; Gazit, Oz M; Puniredd, Sreenivasa Reddy; McNeill, Christopher R; Sonar, Prashant; Haick, Hossam

    2016-06-01

    An ambipolar organic field-effect transistor (OFET) based on poly(diketopyrrolopyrrole-terthiophene) (PDPPHD-T3) is shown by P. Sonar, H. Haick, and co-workers on page 4012 to sensitively detect xylene isomers at low to 40 ppm level in multiple sensing features. Combined with pattern-recognition algorithms, a sole ambipolar FET sensor, rather than arrays of sensors, is able to discriminate highly similar xylene structural isomers from each other.

  4. Field-Effect Transistors: Ultrathin MXene-Micropattern-Based Field-Effect Transistor for Probing Neural Activity (Adv. Mater. 17/2016).

    PubMed

    Xu, Bingzhe; Zhu, Minshen; Zhang, Wencong; Zhen, Xu; Pei, Zengxia; Xue, Qi; Zhi, Chunyi; Shi, Peng

    2016-05-01

    A field-effect transistor (FET) based on ultrathin Ti3 C2 -MXene micropatterns is developed by C. Zhi, P. Shi, and co-workers, as described on page 3333. The FET can be utilized for label-free probing of small molecules in typical biological environments, e.g., for fast detection of action potentials in primary neurons. This device is produced with a microcontact printing technique, harnessing the unique advantages for easy fabrication.

  5. Microfluidics-Based Biosensors: A Microfluidic Paper-Based Origami Nanobiosensor for Label-Free, Ultrasensitive Immunoassays (Adv. Healthcare Mater. 11/2016).

    PubMed

    Li, Xiao; Liu, Xinyu

    2016-06-01

    The first microfluidic paper-based origami nano-biosensor featuring zinc oxide nanowires and an electrochemical impedance spectroscopy biosensing mechanism, for label-free, ultrasensitive immunoassays is reported by X. Li and X. Liu on page 1326. The sensor consists of cellulose paper, a carbon ink electrode, and zinc oxide nanowires directly grown on the top. Possible parallelization of assays and high storage stability render the sensor promising for clinical diagnostics applications.

  6. Cellular Microcultures: Programming Mechanical and Physicochemical Properties of 3D Hydrogel Cellular Microcultures via Direct Ink Writing (Adv. Healthcare Mater. 9/2016).

    PubMed

    McCracken, Joselle M; Badea, Adina; Kandel, Mikhail E; Gladman, A Sydney; Wetzel, David J; Popescu, Gabriel; Lewis, Jennifer A; Nuzzo, Ralph G

    2016-05-01

    R. Nuzzo and co-workers show on page 1025 how compositional differences in hydrogels are used to tune their cellular compliance by controlling their polymer mesh properties and subsequent uptake of the protein poly-l-lysine (green spheres in circled inset). The cover image shows pyramid micro-scaffolds prepared using direct ink writing (DIW) that differentially direct fibroblast and preosteoblast growth in 3D, depending on cell motility and surface treatment.

  7. Photothermal Gene Delivery: Stimuli-Regulated Enzymatically Degradable Smart Graphene-Oxide-Polymer Nanocarrier Facilitating Photothermal Gene Delivery (Adv. Healthcare Mater. 15/2016).

    PubMed

    Kim, Hyunwoo; Kim, Jinhwan; Lee, Minkyung; Choi, Hee Cheul; Kim, Won Jong

    2016-08-01

    On page 1918, Won Jong Kim and co-workers use disulfide bonding for the rational design of graphene oxide (GO) based nanocarriers. In the lower left side, photothermally triggered gene release is illustrated in cancer cell. Polymer-detached GOis exocytosed, and subsequently gets into the macrophage (middle right). In the macrophage, peroxidase binds to GO, thus degrades it to small fragments which are fluorescent.

  8. Dye-Sensitized Solar Cells: The Future of Using Earth-Abundant Elements in Counter Electrodes for Dye-Sensitized Solar Cells (Adv. Mater. 20/2016).

    PubMed

    Briscoe, Joe; Dunn, Steve

    2016-05-01

    Sustainability is an important concept generating traction in the research community. To be really sustainable the full life cycle of a product needs to be carefully considered. A key aspect of this is using elements that are either readily recycled or accessible in the Earth's biosphere. Jigsawing these materials together in compounds to address our future energy needs represents a great opportunity for the current generation of researchers. On page 3802, S. Dunn and J. Briscoe summarize the performance of a selection of alternative materials to replace platinum in the counter electrodes of dye-sensitized solar cells.

  9. Electrospun Scaffolds: Enhanced Lineage-Specific Differentiation Efficiency of Human Induced Pluripotent Stem Cells by Engineering Colony Dimensionality Using Electrospun Scaffolds (Adv. Healthcare Mater. 12/2016).

    PubMed

    Maldonado, Maricela; Ico, Gerardo; Low, Karen; Luu, Rebeccah J; Nam, Jin

    2016-06-01

    Electrospun scaffolds provide soft nanofibrous networks pliable by human induced pluripotent stem cells. J. Nam and co-workers show on page 1408 that such compliant scaffolding leads to the formation of stem cell colonies with a distinctive three-dimensional morphology. The morphological modulation resulted in the lineage-specific differentiation, suggesting a potential means to enhance translational applications of the stem cells.

  10. Generation of Small-Mode Particles via Nucleation of Meteoric Dust in the Upper Haze of Venus

    NASA Astrophysics Data System (ADS)

    Yung, Yuk; Gao, P.; Zhang, X.; Crisp, D.; Bardeen, C. G.

    2012-10-01

    Observations by the SPICAV/SOIR instruments aboard Venus Express has revealed that the Upper Haze of Venus is populated by two particle modes, as reported by Wilquet et al. (J. Geophys. Res., 114, E00B42, 13pp, 2009). In this work we posit that the large mode is due to the upwelling of cloud particles, while the smaller mode is generated by the nucleation of meteoric dust. We test this hypothesis by using version 3.0 of the Community Aerosol and Radiation Model for Atmospheres, first developed by Turco et al. (J. Atmos. Sci., 36, 699-717, 1979) and upgraded by Bardeen et al. (The CARMA 3.0 microphysics package in CESM, Whole Atmosphere Working Group Meeting, 2011). Using the meteoric dust production profile of Kalashnikova et al. (Geophys. Res. Lett., 27, 3293-3296, 2000), the sulfur/sulfate condensation nuclei production profile of Imamura and Hashimoto (J. Atmos. Sci., 58, 3597-3612, 2001), and sulfuric acid vapour production profile of Zhang et al. (Icarus, 217, 714-739, 2012), we numerically simulate a column of the Venus atmosphere from 40 to 100 km above the surface. Our aerosol number density results agree well with Pioneer Venus data from Knollenberg and Hunten (J. Geophys. Res., 85, 8039-8058, 1980), while our gas distribution results match that of Kolodner and Steffes (Icarus, 132, 151-169, 1998). There is a mediocre agreement between our cloud deck size distribution and Pioneer Venus data. The Upper Haze size distribution shows two lognormal distributions overlapping each other, possibly indicating the presence of two modes, though more analysis is required at this time. Finally, we treat the simulated aerosol particles as Mie scatterers and compute their optical parameters. The results show a minimum in the optical depth at a wavelength of 300 nm, comparable to the results of Lacis (J. Atmos. Sci., 32, 1107-1124, 1975).

  11. Climatology and dynamics of nocturnal low-level stratus over the southern West African monsoon region

    NASA Astrophysics Data System (ADS)

    Fink, A. H.; Schuster, R.; Knippertz, P.; van der Linden, R.

    2013-12-01

    the windward side of orography, and radiative cooling on one hand, and 'stratolytic' dry advection and latent heating on the other hand. Future work will focus on the influence of the stratus on the energy and moisture budget and on the West African monsoon system as a whole. Schematic illustration of the cloud formation process for (a) conditions close to the coast and (b) farther inland. Abbreviations are ADV: advection, E: latent heat flux, H: sensible heat flux, EV: evaporation, and NLLJ: nighttime low-level jet. Typical values for the contribution from each process are given. The effect of lifting was estimated by the difference in height and the assumption of a vertical temperature gradient of 0.65K/100 m (Fig. 12 in Schuster et al. 2013, J. Atmos. Sci, 70 (8), 2337-2355.

  12. Changes in the temperature annual cycle in China and their implications for studying climate variability and change

    NASA Astrophysics Data System (ADS)

    Qian, C.; Fu, C.; Wu, Z.

    2011-12-01

    , which is somehow independent of change in the annual mean, explains 40-60% of the spring onset trend in the eastern part of northern China and is attributable to a weakening Asian winter monsoon. Citation: Qian, C., C. Fu, and Z. Wu, 2011: Changes in the amplitude of the temperature annual cycle in China and its implication for climate change research. J. Climate, doi: 10.1175/JCLI-D-11-00006.1 (In press) & Qian, C., C. Fu, Z. Wu, and Z. Yan, 2011: The role of changes in the annual cycle in earlier onset of climatic spring in northern China. Adv. Atmos. Sci., 28(2), 284-296

  13. Aerosol Characteristics on the Alboran Sea, 9-18 October 1982

    DTIC Science & Technology

    1983-12-01

    8217FALO NY AerosDi Characteristics on tne Aiboran Sea, 9—13 Q c t o d e r 19 S 2» (u) tractor rspc, 1/ bep ti’Z—/ cisp S-::-, u...Boundary Layer in the Gulf of Mexico ," Calspan Report, 64 pp. 11. Mack, E.J., R.J. Anderson, C.K. Akers, and T.A. Niziol, 1978: "Aerosol...COMMANDER & DIRECTOR ATTN: DELAS-AS-P U.S. ARMY ATMOS. SCI. LAB WHITE SANDS MISSILE RANGE, NEW MEXICO 88002 USAFETAC/TS SCOTT AFB, IL 62225

  14. Fast time-series prediction using high-dimensional data: evaluating confidence interval credibility.

    PubMed

    Hirata, Yoshito

    2014-05-01

    I propose an index for evaluating the credibility of confidence intervals for future observables predicted from high-dimensional time-series data. The index evaluates the distance from the current state to the data manifold. I demonstrate the index with artificial datasets generated from the Lorenz'96 II model [Lorenz, in Proceedings of the Seminar on Predictability, Vol. 1 (ECMWF, Reading, UK, 1996), p. 1], the Lorenz'96 I model [Hansen and Smith, 2859:TROOCI>2.0.CO;2">J. Atmos. Sci. 57, 2859 (2000).

  15. Sensitivity of Tropical Cyclone Models to the Surface Drag Coefficient in Different Boundary-Layer Schemes

    DTIC Science & Technology

    2011-10-20

    No. N0001411Wx20095 from the U.S. Office of Naval Research and NSF AGS- 0733380 and NSF AGS-0851077, NOAAs Hurricane Research Division and NASA...Black PG D’Asoro EA Drennan WM French JR Niller PP Sanford TB Terril EJ Walsh EJ Zhang JA 2007 Air- sea exchange in hurricanes. Synthesis of...mechanism for tropical cyclone intensification. J. Atmos. Sci., 53, 3528-3540. Drennan WM Zhang JA French JR McCormick C Black PB. 2007 Turbulent

  16. Polarization-Diversity Radar and Lidar Technology in Meteorological Research. A Review of Theory and Measurements,

    DTIC Science & Technology

    1977-07-31

    1952: Cross—Polarization of the Radar Melting Band . Nature, UQ~ 1078—1079. ~ 40 ~Austin, P.M., and Bernie, A. C ., 1950: A Quantitative Study of The...Post , E. A., 1954: Evaluation of C — Band (5.5 cm) Air— borne Weather Radar . United Air Lines, Inc., Denver , Cob . ~ 43 ~At1as, D., and Wexier , R., 1963...Hydrometeors in a Thunderstorm. J. Atmos. Sci., 27, 974—977. Hendry , A. , and McCormick , C . C . , 1968 : A Polarization Diversity Ku— Band Radar for the

  17. Huygens/HASI 2002 balloon test campaign: Probe trajectory and atmospheric vertical profiles reconstruction

    NASA Astrophysics Data System (ADS)

    Gaborit, V.; Fulchignoni, M.; Colombatti, G.; Ferri, F.; Bettanini, C.

    2004-08-01

    In the framework of the activities going on in preparation for the mission of the Huygens probe in Titan's atmosphere (January 2005), the Huygens Atmospheric Structure Instrument (HASI) team scheduled and performed several balloon campaigns to test the HASI sensors' performance in flight conditions in the Earth's atmosphere. In particular, pressure conditions reached during each test are similar to those expected in Titan's lower atmosphere. A 1:1 scaled mock-up of the Huygens probe was launched with a stratospheric balloon in 2001 (Br. Assoc. Adv. Sci. 33 (2001) 1109) and in 2002 (Br. Assoc. Adv. Sci. 34 (2002) 911; Adv. Space. Sci. (2003)) from the G. Broglio base of the Italian Space Agency, located in Trapani Milo (Sicily). In both cases the mock-up was dropped from an altitude higher than 27 and 32 km, respectively, and recovered on the ground after a parachuted descent. In this paper, we describe the results obtained in reconstructing (i) the probe descent trajectory and (ii) the profiles of the physical quantities characterizing the Earth's atmosphere, on the basis of a complete analysis of the data obtained during the HASI 2002 balloon flight experiment. Using temperature and pressure measurements, we are able to reach an accuracy of the order of 0.5% on the altitude reconstruction during the descent. We validate both the models used for trajectory reconstruction and to check the sensors' performance. We describe the problems faced in determining the Huygens probe descent trajectory in Titan's atmosphere focusing our discussion on the critical aspects of the descent reconstruction (such as the uncertainties due to measurement errors, limited knowledge of the atmospheric composition, etc.) and the validity of the adopted assumptions.

  18. Effects of Azaprophen, Scopolamine and Trihexyphenidyl on Schedule-Controlled Behavior, Before and After Chronic Physostigmine

    DTIC Science & Technology

    1990-01-01

    clinically in the treatment of dystonia , such fects on behavior when administered alone (Mc- as the extra-pyramidal effects produced by the Master and... dystonia . Can. J. Neurol. Sci. 13, 42. Loullis, C.C.. R.L. Dean, D.I. Benson, L.R. Meverson and The author thanks Timothy F. Elsmore for helpful com- R.T...Fahq, 1983, Double-blind evaluation of Behav. 12, 409. trihexyphenidyl in dystonia , in: Adv. Neurol., Vol. 37, eds. McMaster. S.B. and J.M. Carney, 1986

  19. Analytical Applications of Scanning Tunneling Microscopy

    DTIC Science & Technology

    1993-10-10

    Univ. Press, Oxford, 1991). 7. E. Betzig and J . K. Trautman. Science 257, 189 (1992). 8. H. Kumar Wickramasinghe, Scient . Am. 261, 74 (1989). 9. H...Academic Press, Boston, 1993. 13. Y. Kuk and P. J . Silverman, Rev. Sci. Instrum . 60, 165 (1989). -9- P. S. Weiss 14. R. J . Hamers, Adv. Phys. Chem...OFFICE OF NAVAL RESEARCH Grant #N00014-91- J -1630 R&T Code 313s002 --- 05 AD-A276 066 Technical Report #9 I IN III 111M11 oi11111111I Analytical

  20. Total OH Reactivity Measurements in the Boreal Forest

    NASA Astrophysics Data System (ADS)

    Praplan, A. P.; Hellén, H.; Hakola, H.; Hatakka, J.

    2015-12-01

    INTRODUCTION Atmospheric total OH reactivity (Rtotal) can be measured (Kovacs and Brune, 2001; Sinha et al., 2008) or it can be calculated according to Rtotal = ∑i kOH+X_i [Xi] where kOH+X_i corresponds to the reaction rate coefficient for the reaction of OH with a given compound Xi and [Xi] its concentration. Studies suggest that in some environments a large fraction of missing reactivity, comparing calculated Rtotal with ambient total OH reactivity measurements (Di Carlo et al., 2004; Hofzumahaus et al., 2009). In this study Rtotal has been measured using the Comparative Reactivity Method (Sinha et al., 2008). Levels of the reference compound (pyrrole, C4H5N) are monitored by gas chromatography every 2 minutes and Rtotal is derived from the difference of reactivity between zero and ambient air. RESULTS Around 36 hours of preliminary total OH reactivity data (30 May until 2 June 2015) are presented in Fig. 1. Its range matches previous studies for this site (Nölscher et al., 2012; Sinha et al., 2010) and is similar to values in another pine forest (Nakashima et al., 2014). The setup used during the period presented here has been updated and more recent data will be presented, as well as a comparison with calculated OH reactivity from measured individual species. ACKNOWLEDGEMENTS This work was supported by Academy of Finland (Academy Research Fellowship No. 275608). The authors acknowledge Juuso Raine for technical support. REFERENCES Di Carlo et al. (2004). Science 304, 722-725.Hofzumahaus et al. (2009). Science 324, 1702-1704.Kovacs and Brune (2001). J. Atmos. Chem. 39, 105-122.Nakashima et al. (2014). Atmos. Env. 85, 1-8.Nölscher et al. (2012). Atmos. Chem. Phys. 12, 8257-8270.Sinha et al. (2008). Atmos. Chem. Phys. 8, 2213-2227.Sinha et al. (2010). Environ. Sci. Technol. 44, 6614-6620.

  1. Teaching Astronomy Really Dynamically Involving Sci-Fi, or the Other TARDISTeaching Astronomy Really Dynamically Involving Sci-Fi, or the Other TARDIS

    NASA Astrophysics Data System (ADS)

    Larsen, K.

    2014-07-01

    Teaching science through science fiction films, series, and novels is not a new phenomenon; however, how many of us are still stuck using the original Star Trek (or even The Next Generation), Contact, and Deep Impact? These works often predate our current students' births by many years. Faculty members may still find them exciting and relevant, but we should periodically re-evaluate their relevance and effectiveness. In addition, there are works of popular culture in other genres, such as comedy and cartoons, that feature references to astronomical topics. A new generation of students should be taught through a new generation of media. This hands-on workshop introduced timely examples of popular culture that can be utilized to make astronomical concepts come alive in the introductory classroom, as well as methods for fishing for future examples as new media continues to be released.

  2. Response to V. A. Marichev's reply [Surf. Sci. 605(2011)2097] to the comments written by E. M. Gutman [Surf. Sci. 605(2011)1923

    NASA Astrophysics Data System (ADS)

    Gutman, Emmanuel M.

    2012-04-01

    For the first time, it is shown that the first and second Gokhshtein equations were originally derived by him from false fundamental equations violating criteria for applications of Maxwell relations and Legendre transforms. These equations are erroneous. For example, the direct connection between the electrode potential and charge density is actually independent of the tangential elastic strain of flat ideally polarizable electrode. The sequence of equations of Shuttleworth-Herring-Eriksson-Couchman-Jesser-Everet-Davidson-Rusanov has a common mathematical defect which consists of illegally equating the total differential to the partial differential.

  3. Numerical solution of the stochastic collection equation—comparison of the Linear Discrete Method with other methods

    NASA Astrophysics Data System (ADS)

    Simmel, Martin; Trautmann, Thomas; Tetzlaff, Gerd

    The Linear Discrete Method is used to solve the Stochastic Collection Equation (SCE) numerically. Comparisons are made with the Method of Moments, the Berry-Reinhardt model and the Linear Flux Method. Simulations for all numerical methods are shown for the kernel after Golovin [Bull. Acad. Sci. USSR, Geophys. Ser. 5 (1963) 783] and are compared with the analytical solution for two different initial distributions. BRM seems to give the best results and LDM gives good results, too. LFM overestimates the drop growth for the right tail of the distribution and MOM does the same but over the entire drop spectrum. For the hydrodynamic kernel after Long [J. Atmos. Sci. 31 (1974) 1040], simulations are presented using the four numerical methods (LDM, MOM, BRM, LFM). Especially for high resolutions, the solutions of LDM and LFM approach each other very closely. In addition, LDM simulations using the hydrodynamic kernel after Böhm [Atmos. Res. 52 (1999) 167] are presented, which show good correspondence between low- and high-resolution results. Computation efficiency is especially important when numerical schemes are to be included in larger models. Therefore, the computation times of the four methods were compared for the cases with the Golovin kernel. The result is that LDM is the fastest method by far, needing less time than other methods by a factor of 2-7, depending on the case and the bin resolution. For high resolutions, MOM is the slowest. For the lowest resolution, this holds for LFM.

  4. Aerosol Optical Depth over Europe: Evaluation of the CALIOPE air quality modelling system with direct-sun AERONET observations

    NASA Astrophysics Data System (ADS)

    Basart, Sara; Pay, María. Teresa; Pérez, Carlos; Cuevas, Emilio; Jorba, Oriol; Piot, Matthias; María Baldasano, Jose

    2010-05-01

    probability of detection) of AOD when using CMAQ+DREAM8b compared to CMAQ-alone simulations. An accurate analysis of the relative contributions of anthropogenic aerosols and desert dust to AOD over Europe and their seasonality will be also presented. References: Baldasano J.M, P. Jiménez-Guerrero, O. Jorba, C. Pérez, E. López, P. Güereca, F. Martin, M. García-Vivanco, I. Palomino, X. Querol, M. Pandolfi, M.J. Sanz and J.J. Diéguez: "CALIOPE: An operational air quality forecasting system for the Iberian Peninsula, Balearic Islands and Canary Islands- First annual evaluation and ongoing developments", Adv. Sci. and Res., 2: 89-98, 2008. Baldasano J.M., L. P. Güereca, E. López, S. Gassó, P. Jimenez-Guerrero. "Development of a high resolution (1 km x 1 km, 1 h) emission model for Spain: the High-Elective Resolution Modelling Emission System (HERMES)". Atmospheric Environment, 42: 7215-7233 doi: 10.1016/j.atmosenv.2008.07.026, 2008. Basart, S., Pérez, C., Cuevas, E., Baldasano, J. M. and Gobbi, G. P. "Aerosol characterization in Northern Africa, Northeastern Atlantic, Mediterranean Basin and Middle East from direct-sun AERONET observations", Atmos. Chem. Phys.., 9, 7707-7745, 2009. Jiménez-Guerrero, P., Pérez, C., Jorba, O. and Baldasano, J. M. "Contribution of Saharan dust in an integrated air quality system and its on-line assessment", Geophys. Res. Lett., 35(3), 2008. O'Neill, N. T., Dubovik, O., and Eck, T. F.: A modified Angstrom coefficient for the characterization of sub-micron aerosols, App. Opt., 40(14), 2368-2375, 2001. Pérez, C., Nickovic, S., Pejanovic, G., Baldasano, J. M. and Ozsoy, E. "Interactive dust-radiation modeling: A step to improve weather forecasts", Geophys. Res., 11(D16206),doi:10.1029/2005JD006717, 2006. Rodríguez, S., Querol, X., Alastuey, A., Kallos, G. and Kakaliagou, O. "Saharan dust contributions to PM10 and TSP levels in Southern and Eastern Spain", Atmos. Environ., 35, 2433-2447, 2001.

  5. How melt stretching affect the brittle-ductile transition temperature of polymer glasses

    NASA Astrophysics Data System (ADS)

    Cheng, Shiwang; Wang, Shi-Qing

    2013-03-01

    Upon increasing temperature a brittle polymer glass can turn ductile. PMMA is a good example. For a while this brittle-ductile transition (BDT) was thought to be determined by the emergence of a secondary relaxation....1-3 On the other hand, it has been known for a long time...4-6 that predeformation in the melt state (e.g., melt stretching) can also make brittle glasses behave in a ductile manner. This transformation has recently received a satisfactory explanation based on a picture of structural hybrid for polymer glasses....7 It appears that BDT is dictated by the relative mechanical characteristics of the primary structure (due to the van der Waals bonds) and the chain network. The present work, based on conventional Instron tensile extension tests and DMA tests, shows that melt stretching does not alter the secondary relaxation behavior of PMMA and PC yet can turn them the brittle PMMA ductile and the ductile PC brittle. Moreover, sufficient melt stretching makes the brittle PS ductile although it does not produce any secondary relaxation process..1. Monnerie, L.; Laupretre, F.; Halary, J. L. Adv. Polym. Sci2005, 187, 35-213. 2. Monnerie, L.; Halary, J. L.; Kausch, H. Adv. Polym. Sci2005, 187, 215-364. 3. Wu, S. J. Appl. Polym. Sci.1992, 46, (4), 619-624. 4. Vincent, P. I. Polymer1960, 1, (0), 425-444. 5. Harris, J. S.; Ward, I. M. J. Mater. Sci.1970, 5, (7), 573-579. 6. Ender, D. H.; Andrews, R. D. J. Appl. Phys.1965, 36, (10), 3057-3062. 7. Zartman, G. D.; Cheng, S.; Li, X.; Lin, F.; Becker, M. L.; Wang, S.-Q. Macromolecules2012, 45, (16), 6719-6732.

  6. Neural and Biological Soldier Enhancement: From SciFi to Deployment

    DTIC Science & Technology

    2009-10-01

    and force, extra- and ultra-sensory perception , side-effect free 72-hours unbowed alertness, or brain-based Report Documentation Page Form...Deployment 33 - 2 RTO-MP-HFM-181 augmented reality perception , become conceivable and increasingly within reach. A lot of these extraordinary...visionary or exotic, might severely impact NATO forces´ future performance. In addition, a shift in society´s perception of the parting rule between human

  7. SciCADE 95: International conference on scientific computation and differential equations

    SciTech Connect

    1995-12-31

    This report consists of abstracts from the conference. Topics include algorithms, computer codes, and numerical solutions for differential equations. Linear and nonlinear as well as boundary-value and initial-value problems are covered. Various applications of these problems are also included.

  8. Implanted functional electrical stimulation: case report of a paraplegic patient with complete SCI after 9 years

    PubMed Central

    2014-01-01

    Backgrounds Experience of an implanted functional electrical stimulation neuroprosthesis (FES) associating 8-channel epimysial and 4-channel neural stimulations. The primary objective consisted in presenting clinical and technological experiences based on a 9-year follow-up of one patient implanted with this FES device. The secondary objective consisted in assessing resulting functional benefits. Methods One patient recruited in 1996 within the European Stand Up and Walk Project benefited from a 9-year follow-up with clinical and technological evaluations. Results The patient was still using the system nine years later making this a unique case, even when compared to other similar studies. The analysis of muscular response to FES underlined the great variability of stimulation thresholds evolution (−26% to +360%, mean +110%) and quality of the induced contraction. Three muscles out of five scored at least 4/5 on the Medical Research Council scale, all stimulated via neural pathways. The patient used the system once a week for 6 years, up to 2006, due to lack of use, the FES-induced muscular response worsened even though the implant was properly functioning, leading to significant decline in gait performances (best 3.45 m/s on 2.9 m), due to muscle fatigue and loss of muscle mass. Conclusion Two major issues arise: first the importance of muscle fatigue, underlining the relevance of muscle strength training, and second technological hurdles raising up the question of neural vs. epimysial FES. This advanced technology proves the concept of restoring lower limb motor functions in patients with spinal cord injury. The main features of the stimulation device remain stable even after long periods of inactivity, yet there is a real need for close clinical and technological monitoring. PMID:24564879

  9. SCI with Brain Injury: Bedside to Bench Modeling for Developing Treatment and Rehabilitation Strategies

    DTIC Science & Technology

    2013-10-01

    DOCUSATE 10 ACETAMINOPHEN 9 ACETAMINOPHEN 7 SENNA 9 SENNA 4 BISACODYL 7 BISACODYL 5 OMEPRAZOLE 7 OMEPRAZOLE 1 ALBUTEROL 6 ALBUTEROL 2 LIDOCAINE 5... LIDOCAINE 1 ASCORBIC ACID 4 ASCORBIC ACID 2 HYDROCODONE/ACETAMINOPHEN 4 HYDROCODONE/ACETAMINOPHEN 2 ONDANSETRON 4 ONDASENTRON 1 ENOXAPARIN 3 ENOXAPARIN 3...7 SENNA 4 LIDOCAINE 5 LIDOCAINE 1 ONDANSETRON 5 ONDASETRON 1 GABAPENTIN 4 GABAPENTIN 2 ASCORBIC ACID 4 ASCORBIC ACID 1 BISACODYL 4 BISACODYL 1

  10. SCI with Brain Injury: Bedside to Bench Modeling for Developing Treatment and Rehabilitation Strategies

    DTIC Science & Technology

    2013-10-01

    BISACODYL 5 OMEPRAZOLE 7 OMEPRAZOLE 1 ALBUTEROL 6 ALBUTEROL 2 LIDOCAINE 5 LIDOCAINE 1 ASCORBIC  ACID 4 ASCORBIC  ACID 2 HYDROCODONE/ACETAMINOPHEN 4...Frequency ACETAMINOPHEN 10 ACETAMINOPHEN 7 DOCUSATE 8 DOCUSATE 8 OMEPRAZOLE 8 OMEPRAZOLE 1 SENNA 7 SENNA 4 LIDOCAINE 5 LIDOCAINE 1 ONDANSETRON 5 ONDASETRON 1

  11. SCI with Brain Injury: Bedside-to-Bench Modeling for Developing Treatment and Rehabilitation Strategies

    DTIC Science & Technology

    2012-10-01

    12 VA Frequency SCVMC Frequency ACETAMINOPHEN 10 ACETAMINOPHEN 7 DOCUSATE 8 DOCUSATE 8 OMEPRAZOLE 8 OMEPRAZOLE 1 SENNA 7 SENNA 4 LIDOCAINE 5... LIDOCAINE 1 ONDANSETRON 5 ONDASETRON 1 GABAPENTIN 4 GABAPENTIN 2 ASCORBIC  ACID 4 ASCORBIC ACID 1 BISACODYL 4 BISACODYL 1 TRAZODONE 3 TRAZADONE 5...DOCUSATE 9 DOCUSATE 10 ACETAMINOPHEN 9 ACETAMINOPHEN 7 SENNA 9 SENNA 4 BISACODYL 7 BISACODYL 5 OMEPRAZOLE 7 OMEPRAZOLE 1 ALBUTEROL 6 ALBUTEROL 2 LIDOCAINE 5

  12. SCI with Brain Injury: Bedside-to-Bench Modeling for Developing Treatment and Rehabilitation Strategies

    DTIC Science & Technology

    2012-10-01

    LIDOCAINE 5 LIDOCAINE 1 ONDANSETRON 5 ONDASETRON 1 GABAPENTIN 4 GABAPENTIN 2 ASCORBIC  ACID 4 ASCORBIC ACID 1 BISACODYL 4 BISACODYL 1 TRAZODONE 3... LIDOCAINE 5 LIDOCAINE 1 ASCORBIC  ACID 4 ASCORBIC  ACID 2 HYDROCODONE/ACETAMINOPHEN 4 HYDROCODONE/ACETAMINOPHEN 2 ONDANSETRON 4 ONDASENTRON 1

  13. A Journey into the Future: Using Sci-Fi Stories with EFL Learners.

    ERIC Educational Resources Information Center

    Yang, Anson

    2001-01-01

    Discusses using science fiction stories in the English-as-a-Foreign-Language (EFL) classroom. Presents experiences in a science fiction course with some successful methods in eliciting EFL students' discussion. Concludes that using both film and text versions of science fiction stories can be useful devices in helping EFL students participate…

  14. A character network study of two Sci-Fi TV series

    NASA Astrophysics Data System (ADS)

    Tan, M. S. A.; Ujum, E. A.; Ratnavelu, K.

    2014-03-01

    This work is an analysis of the character networks in two science fiction television series: Stargate and Star Trek. These networks are constructed on the basis of scene co-occurrence between characters to indicate the presence of a connection. Global network structure measures such as the average path length, graph density, network diameter, average degree, median degree, maximum degree, and average clustering coefficient are computed as well as individual node centrality scores. The two fictional networks constructed are found to be quite similar in structure which is astonishing given that Stargate only ran for 18 years in comparison to the 48 years for Star Trek.

  15. Sci-Tech Books of 1977: One Hundred Outstanding Titles for General Library Collections

    ERIC Educational Resources Information Center

    Mount, Ellis; Crockett, Edith S.

    1978-01-01

    This annotated bibliography is intended for public library collections, although many selections are worthy of inclusion in college or special libraries. Subdivisions listed are: animal life, anthropology, biology, earth sciences, energy, environmental sciences, health, natural history, plants, psychology, and transportation. (JAB)

  16. SCI-U: E-learning for patient education in spinal cord injury rehabilitation

    PubMed Central

    Shepherd, John D.; Badger-Brown, Karla M.; Legassic, Matthew S.; Walia, Saagar; Wolfe, Dalton L.

    2012-01-01

    Background/objectives To develop an online patient education resource for use in spinal cord injury rehabilitation. Participants The development process involved more than 100 subject-matter experts (SMEs) (rehabilitation professionals and consumers) from across Canada. Preliminary evaluation was conducted with 25 end-users. Methods An iterative development process was coordinated by a project team; SMEs (including patients) developed the content in working groups using wiki-based tools. Multiple rounds of feedback based on early prototypes helped improve the courses during development. Results Five courses were created, each featuring more than 45 minutes of video content and hundreds of media assets. Preliminary evaluation results indicate that users were satisfied by the courses and perceived them to be effective. Conclusions This is an effective process for developing multimedia patient education resources; the involvement of patients in all parts of the process was particularly helpful. Future work will focus on implementation, integration into clinical practice and other delivery formats (smart phones, tablets). PMID:23031169

  17. Report to the National Park Service for Permit LAKE-2014-SCI-002

    SciTech Connect

    Burnley, Pamela C.

    2015-06-01

    The overall purpose of the study is to determine how to use existing geologic data to predict gamma-ray background levels as measured during aerial radiological surveys. Aerial radiological surveys have typically been for resource exploration purposes but are now also used for homeland security purposes and nuclear disaster assessment as well as determining the depth of snowpack. Foreknowledge of the background measured during aerial radiological survey will be valuable for all the above applications. The gamma-ray background comes from the rocks and soil within the first 30 cm of the earth’s surface in the area where the survey is being made. The background should therefore be predictable based on an understanding of the distribution and geochemistry of the rocks on the surface. We are using a combination of geologic maps, remote sensing imagery and geochemical data from existing databases and the scientific literature to develop a method for predicting gamma-ray backgrounds. As part of this project we have an opportunity to ground truth our technique along a survey calibration line near Lake Mojave that is used by the Remote Sensing Lab (RSL) of National Security Technologies, LLC (NSTec). RSL makes aerial measurements along this line on a regular basis, so the aerial background in the area is well known. By making ground-based measurements of the gamma-ray background and detailed observations of the geology of the ground surface as well as local topography we will have the data we need to make corrections to the models we build based on the remote sensing and geologic data. Our project involves collaborators from the Airborne Geophysics Section of the Geological Survey of Canada as well as from NSTec’s RSL. Findings

  18. National Computational Infrastructure for Lattice Gauge Theory SciDAC-2 Closeout Report

    SciTech Connect

    Sun, Xian-He

    2013-08-01

    As part of this project work, researchers from Vanderbilt University, Fermi National Laboratory and Illinois Institute of technology developed a real-time cluster fault-tolerant cluster monitoring framework. This framework is open source and is available for download upon request. This work has also been used at Fermi Laboratory, Vanderbilt University and Mississippi State University across projects other than LQCD. The goal for the scientific workflow project is to investigate and develop domain-specific workflow tools for LQCD to help effectively orchestrate, in parallel, computational campaigns consisting of many loosely-coupled batch processing jobs. Major requirements for an LQCD workflow system include: a system to manage input metadata, e.g. physics parameters such as masses, a system to manage and permit the reuse of templates describing workflows, a system to capture data provenance information, a systems to manage produced data, a means of monitoring workflow progress and status, a means of resuming or extending a stopped workflow, fault tolerance features to enhance the reliability of running workflows. Requirements for an LQCD workflow system are available in documentation.

  19. From Sci-Fi to Reality--Mobile Robots Get the Job Done

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2006-01-01

    Robots are simply computers that can interact with their environment. Some are fixed in place in industrial assembly plants for cars, appliances, micro electronic circuitry, and pharmaceuticals. Another important category of robots is the mobiles, machines that can be driven to the workplace, often designed for hazardous duty operation or…

  20. Development of Practical and Rapid Field-Based Therapies for SCI

    DTIC Science & Technology

    2014-02-01

    cells secreting growth factors. We have identified allogeneic bone marrow stromal cells (BMSC) as a potential source for cell transplantation for the...following reasons: 1) BMSCs obtained from unrelated bone marrow donors can be obtained, expanded, genetically modified and banked to serve as a...Allogeneic Bone Marrow Stromal Cells. Specific Aim 2: Examine Anatomical and Behavioral Outcomes of Battlefield-Relevant Treatments After Acute Contusive